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TARA_ERS490610_N000080_74 / Result of BLASTP

browse BLASTP result of all genes from this scaffold

subject	subject definition	idt	len	mis	gap	q.start	q.end	s.start	s.end	evalue	bit.score
subject	subject definition	idt	len	mis	gap	q.start	q.end	s.start	s.end	evalue	bit.score
rs:WP_018126711	hypothetical protein [Balneola vulgaris].	89.23	297	32	0	1	297	1	297	0.0	561
rs:WP_020402276	hypothetical protein [Gracilimonas tropica].	89.83	295	30	0	1	295	1	295	0.0	560
rs:WP_038132876	methenyltetrahydrofolate cyclohydrolase [Verrucomicrobia bacterium SCGC AAA168-F10].	82.03	295	53	0	1	295	1	295	3e-179	509
rs:WP_022185830	folD protein [Bacteroides dorei CAG:222].	53.95	291	134	0	4	294	2	292	5e-109	330
rs:WP_007845553	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides dorei].	53.95	291	134	0	4	294	2	292	7e-109	330
rs:WP_007844733	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides].	53.95	291	134	0	4	294	2	292	8e-109	330
rs:WP_007836928	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides dorei].	53.95	291	134	0	4	294	2	292	2e-108	328
rs:WP_005839102	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides vulgatus].	53.61	291	135	0	4	294	2	292	3e-108	328
rs:WP_007213340	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides cellulosilyticus].	53.79	290	134	0	5	294	3	292	7e-108	327
rs:WP_022053585	bifunctional protein FolD [Bacteroides plebeius CAG:211].	53.79	290	134	0	5	294	3	292	8e-108	327
tr:A0A015PAU4_BACFG	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein {ECO:0000313|EMBL:EXY31924.1}; Flags: Fragment;	53.45	290	135	0	5	294	2	291	8e-108	327
sp:FOLD_BACV8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	53.61	291	135	0	4	294	2	292	9e-108	327
rs:WP_044132656	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides fragilis].	53.45	290	135	0	5	294	1	290	1e-107	327
rs:WP_004312924	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides].	53.45	290	135	0	5	294	3	292	2e-107	326
rs:WP_008999879	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides sp. D2].	53.10	290	136	0	5	294	3	292	2e-107	326
rs:WP_032843786	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides].	53.10	290	136	0	5	294	3	292	3e-107	326
rs:WP_007765672	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides finegoldii].	53.10	290	136	0	5	294	3	292	3e-107	326
tr:D6D587_9BACE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	53.45	290	135	0	5	294	3	292	3e-107	325
tr:J9H784_9ZZZZ	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EJX10055.1};	53.26	291	136	0	4	294	2	292	4e-107	325
rs:WP_007216115	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides].	53.45	290	135	0	5	294	3	292	5e-107	325
rs:WP_025075509	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides faecichinchillae].	53.45	290	135	0	5	294	3	292	5e-107	325
rs:WP_022039908	bifunctional protein FolD [Bacteroides sp. CAG:702].	53.10	290	136	0	5	294	3	292	5e-107	325
tr:J9GSA4_9ZZZZ	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EJX05498.1};	53.61	291	135	0	4	294	2	292	6e-107	325
rs:WP_017141419	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides].	53.45	290	135	0	5	294	3	292	8e-107	325
rs:WP_022209387	folD protein [Bacteroides cellulosilyticus CAG:158].	53.45	290	135	0	5	294	3	292	9e-107	325
rs:WP_009121550	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides].	53.45	290	135	0	5	294	3	292	9e-107	324
rs:WP_014560666	5,10-methylene-tetrahydrofolate dehydrogenase [Ignavibacterium album].	52.26	287	137	0	4	290	2	288	9e-107	324
rs:WP_022136766	folD protein [Bacteroides acidifaciens].	53.10	290	136	0	5	294	3	292	1e-106	324
rs:WP_013617032	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides salanitronis].	52.76	290	137	0	5	294	3	292	1e-106	324
rs:WP_007561124	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides plebeius].	53.10	290	136	0	5	294	3	292	1e-106	324
rs:WP_005681584	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides].	53.10	290	136	0	5	294	3	292	1e-106	324
tr:A5ZIX8_9BACE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	53.10	290	136	0	5	294	13	302	1e-106	324
rs:WP_004304330	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides].	52.76	290	137	0	5	294	3	292	2e-106	323
rs:WP_009131008	FolD protein [Bacteroides oleiciplenus].	53.45	290	135	0	5	294	3	292	2e-106	323
rs:WP_005940729	FolD protein [Bacteroides massiliensis].	52.92	291	137	0	4	294	2	292	2e-106	323
rs:WP_004289917	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides eggerthii].	53.45	290	135	0	5	294	3	292	2e-106	323
sp:FOLD_BACTN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.76	290	137	0	5	294	3	292	2e-106	323
rs:WP_016274276	FolD protein [Bacteroides uniformis].	53.10	290	136	0	5	294	3	292	2e-106	323
rs:WP_016662180	FolD protein [Bacteroides stercoris].	53.10	290	136	0	5	294	3	292	2e-106	323
rs:WP_005831560	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides].	53.10	290	136	0	5	294	3	292	2e-106	323
rs:WP_022104536	bifunctional protein FolD [Bacteroides stercoris CAG:120].	52.76	290	137	0	5	294	3	292	3e-106	323
rs:WP_025834459	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides stercorirosoris].	53.45	290	135	0	5	294	3	292	3e-106	323
rs:WP_007755761	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides finegoldii].	52.76	290	137	0	5	294	3	292	3e-106	323
rs:WP_005807539	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides fragilis].	53.10	290	136	0	5	294	3	292	4e-106	323
rs:WP_022275480	bifunctional protein FolD [Bacteroides finegoldii CAG:203].	52.76	290	137	0	5	294	3	292	4e-106	323
tr:J9F8B6_9ZZZZ	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EJW90698.1};	52.76	290	137	0	5	294	3	292	4e-106	323
rs:WP_022507891	folD protein [Bacteroides sp. CAG:98].	52.92	291	137	0	4	294	30	320	5e-106	323
rs:WP_005798817	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides fragilis].	53.10	290	136	0	5	294	3	292	5e-106	322
rs:WP_044161723	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides reticulotermitis].	52.41	290	138	0	5	294	3	292	6e-106	322
rs:WP_021970768	MULTISPECIES: bifunctional protein FolD [environmental samples].	53.45	290	135	0	5	294	3	292	6e-106	322
sp:FOLD_BACFN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	53.10	290	136	0	5	294	3	292	6e-106	322
rs:WP_008648793	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides sp. 3_1_23].	52.41	290	138	0	5	294	3	292	6e-106	322
rs:WP_022164263	bifunctional protein FolD [Bacteroides sp. CAG:633].	52.41	290	138	0	5	294	3	292	7e-106	322
rs:WP_010538856	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides].	52.41	290	138	0	5	294	3	292	8e-106	322
rs:WP_004321461	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides ovatus].	52.41	290	138	0	5	294	3	292	9e-106	322
rs:WP_009038180	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides sp. D20].	52.76	290	137	0	5	294	3	292	1e-105	322
rs:WP_005652736	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides stercoris].	52.76	290	137	0	5	294	3	292	1e-105	322
rs:WP_007665232	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides].	53.10	290	136	0	5	294	3	292	1e-105	322
rs:WP_032535743	MULTISPECIES: bifunctional protein FolD [Bacteroides].	53.10	290	136	0	5	294	3	292	1e-105	322
tr:A7M2K8_BACO1	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	52.41	290	138	0	5	294	3	292	1e-105	322
rs:WP_005832477	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides uniformis].	52.76	290	137	0	5	294	3	292	1e-105	322
rs:WP_046147955	5,10-methylene-tetrahydrofolate cyclohydrolase [Parabacteroides goldsteinii].	51.55	291	141	0	4	294	7	297	2e-105	322
rs:WP_016276956	FolD protein [Bacteroides massiliensis].	52.58	291	138	0	4	294	2	292	2e-105	321
rs:WP_025017501	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides sartorii].	52.58	291	138	0	4	294	2	292	2e-105	321
rs:WP_022391648	bifunctional protein FolD [Bacteroides intestinalis CAG:315].	52.76	290	137	0	5	294	3	292	2e-105	321
rs:WP_005815032	bifunctional protein FolD [Bacteroides fragilis].	52.76	290	137	0	5	294	3	292	2e-105	321
rs:WP_007566899	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides].	52.76	290	137	0	5	294	3	292	2e-105	321
rs:WP_009292815	MULTISPECIES: bifunctional protein FolD [Bacteroides].	52.76	290	137	0	5	294	3	292	3e-105	321
rs:WP_013547396	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides helcogenes].	52.41	290	138	0	5	294	3	292	3e-105	321
rs:WP_021847517	bifunctional protein FolD [Bacteroides sp. CAG:598].	52.41	290	138	0	5	294	3	292	3e-105	321
rs:WP_022130949	bifunctional protein FolD [Bacteroides sp. CAG:530].	52.41	290	138	0	5	294	3	292	3e-105	321
rs:WP_022384171	tetrahydrofolate dehydrogenase [Bacteroides sp. CAG:462].	52.76	290	137	0	5	294	3	292	4e-105	320
rs:WP_039161847	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides uniformis].	52.41	290	138	0	5	294	3	292	4e-105	320
rs:WP_027326339	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides pyogenes].	52.07	290	139	0	5	294	3	292	4e-105	320
rs:WP_044227374	5,10-methylene-tetrahydrofolate cyclohydrolase [Coprobacter sp. 177].	49.83	291	146	0	4	294	2	292	5e-105	320
rs:WP_018709577	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides].	52.41	290	138	0	5	294	3	292	5e-105	320
rs:WP_022019505	bifunctional protein FolD [Bacteroides sp. CAG:661].	52.41	290	138	0	5	294	3	292	6e-105	320
rs:WP_022470839	bifunctional protein FolD [Bacteroides thetaiotaomicron CAG:40].	52.41	290	138	0	5	294	3	292	6e-105	320
rs:WP_039162807	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides uniformis].	52.41	290	138	0	5	294	3	292	6e-105	320
rs:WP_005930201	FolD protein [Bacteroides salyersiae].	52.41	290	138	0	5	294	3	292	1e-104	319
rs:WP_021930790	bifunctional protein FolD [Tannerella sp. CAG:118].	49.83	291	146	0	4	294	2	292	1e-104	319
rs:WP_008145419	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides].	52.76	290	137	0	5	294	3	292	1e-104	319
rs:WP_008762123	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides sp. 1_1_14].	52.41	290	138	0	5	294	3	292	1e-104	319
rs:WP_018675488	5,10-methylene-tetrahydrofolate dehydrogenase [Riemerella columbina].	52.74	292	137	1	3	294	2	292	1e-104	319
rs:WP_032596058	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides fragilis].	52.76	290	137	0	5	294	3	292	1e-104	319
rs:WP_035448874	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides uniformis].	52.41	290	138	0	5	294	3	292	1e-104	319
rs:WP_018110036	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides propionicifaciens].	50.00	290	145	0	5	294	3	292	2e-104	319
rs:WP_025605865	5,10-methylene-tetrahydrofolate cyclohydrolase [Pontibacter actiniarum].	52.41	290	138	0	5	294	3	292	2e-104	318
rs:WP_007654087	5,10-methylene-tetrahydrofolate dehydrogenase [Parabacteroides goldsteinii].	50.86	291	143	0	4	294	7	297	2e-104	318
rs:WP_021936662	folD protein [Bacteroides sp. CAG:189].	52.07	290	139	0	5	294	3	292	2e-104	318
rs:WP_012843458	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodothermus marinus].	53.98	289	131	1	3	291	2	288	3e-104	318
rs:WP_042373084	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroidaceae bacterium MS4].	52.07	290	139	0	5	294	3	292	3e-104	318
rs:WP_021644386	tetrahydrofolate dehydrogenase [Bacteroides pyogenes].	51.72	290	140	0	5	294	3	292	3e-104	318
rs:WP_025666477	5,10-methylene-tetrahydrofolate cyclohydrolase [Aquimarina megaterium].	52.08	288	138	0	4	291	2	289	4e-104	318
rs:WP_007481664	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides salyersiae].	52.07	290	139	0	5	294	3	292	4e-104	318
rs:WP_024770844	5,10-methylene-tetrahydrofolate cyclohydrolase [Aquimarina macrocephali].	51.74	288	139	0	4	291	2	289	5e-104	317
rs:WP_010800447	MULTISPECIES: FolD protein [Parabacteroides].	51.20	291	142	0	4	294	7	297	5e-104	318
rs:WP_038260910	5,10-methylene-tetrahydrofolate cyclohydrolase [Zhouia amylolytica].	52.08	288	138	0	4	291	2	289	9e-104	317
rs:WP_007486456	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides nordii].	52.41	290	138	0	5	294	3	292	1e-103	316
rs:WP_024997169	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides graminisolvens].	51.38	290	141	0	5	294	6	295	1e-103	317
rs:WP_034243895	5,10-methylene-tetrahydrofolate cyclohydrolase [Aquimarina sp. 22II-S11-z7].	51.39	288	140	0	4	291	2	289	1e-103	316
rs:WP_002561162	FolD protein [Bacteroides sp. HPS0048].	52.41	290	138	0	5	294	3	292	3e-103	315
rs:WP_009316656	5,10-methylene-tetrahydrofolate dehydrogenase [Tannerella sp. 6_1_58FAA_CT1].	50.17	291	145	0	4	294	2	292	3e-103	316
rs:WP_046151351	5,10-methylene-tetrahydrofolate cyclohydrolase [Parabacteroides sp. HGS0025].	50.52	291	144	0	4	294	7	297	3e-103	315
rs:WP_037980964	5,10-methylene-tetrahydrofolate cyclohydrolase [Tannerella sp. oral taxon BU063].	48.81	293	150	0	2	294	5	297	5e-103	315
rs:WP_009125238	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides fluxus].	53.10	290	136	0	5	294	3	292	5e-103	315
rs:WP_024995102	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides paurosaccharolyticus].	51.20	291	142	0	4	294	2	292	6e-103	315
rs:WP_028727002	5,10-methylene-tetrahydrofolate cyclohydrolase [Parabacteroides gordonii].	50.52	291	144	0	4	294	7	297	8e-103	315
rs:WP_027471241	5,10-methylene-tetrahydrofolate cyclohydrolase [Saccharicrinis fermentans].	52.23	291	139	0	4	294	2	292	9e-103	314
rs:WP_046312434	5,10-methylene-tetrahydrofolate cyclohydrolase [Pontibacter korlensis].	50.34	290	144	0	5	294	3	292	9e-103	314
rs:WP_014067468	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodothermus marinus].	53.06	294	135	2	3	295	2	293	1e-102	314
rs:WP_044229255	methenyltetrahydrofolate cyclohydrolase [Phaeodactylibacter xiamenensis].	50.86	291	143	0	4	294	2	292	1e-102	314
rs:WP_022390962	MULTISPECIES: bifunctional protein FolD [Porphyromonadaceae].	50.17	291	145	0	4	294	2	292	2e-102	313
rs:WP_014226159	5,10-methylene-tetrahydrofolate dehydrogenase [Tannerella forsythia].	49.48	291	147	0	4	294	7	297	3e-102	313
rs:WP_045439019	5,10-methylene-tetrahydrofolate dehydrogenase [bacterium UASB270].	50.85	293	144	0	1	293	1	293	4e-102	313
rs:WP_027885366	5,10-methylene-tetrahydrofolate cyclohydrolase [Mesonia mobilis].	50.87	287	141	0	5	291	3	289	4e-102	313
rs:WP_037998846	5,10-methylene-tetrahydrofolate cyclohydrolase [Tannerella sp. oral taxon BU063].	48.46	293	151	0	2	294	5	297	5e-102	313
rs:WP_026711438	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium filum].	51.39	288	140	0	4	291	2	289	5e-102	312
rs:WP_018667311	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides gallinarum].	52.41	290	138	0	5	294	3	292	6e-102	312
rs:WP_021891423	bifunctional protein FolD [Bacteroides sp. CAG:20].	51.71	292	141	0	4	295	2	293	6e-102	312
rs:WP_041993331	5,10-methylene-tetrahydrofolate cyclohydrolase [Capnocytophaga cynodegmi].	52.61	287	136	0	4	290	2	288	6e-102	312
gpu:AP013045_2582	tetrahydrofolate dehydrogenase/cyclohydrolase,NAD(P)-binding domain protein [Tannerella forsythia KS16]	49.48	291	147	0	4	294	7	297	7e-102	312
rs:WP_022192893	MULTISPECIES: bifunctional protein FolD [Parabacteroides].	49.83	291	146	0	4	294	7	297	1e-101	312
rs:WP_046826005	5,10-methylene-tetrahydrofolate cyclohydrolase [Tannerella forsythia].	49.14	291	148	0	4	294	7	297	1e-101	312
rs:WP_029596651	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium sp. ACAM 123].	51.38	290	141	0	4	293	2	291	1e-101	311
rs:WP_035072500	5,10-methylene-tetrahydrofolate cyclohydrolase [Anditalea andensis].	53.10	290	136	0	5	294	2	291	1e-101	311
rs:WP_029904919	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella sp. 10(H)].	49.48	291	147	0	4	294	2	292	1e-101	311
rs:WP_045972533	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium sp. 316].	51.22	287	140	0	5	291	3	289	2e-101	311
rs:WP_038000911	5,10-methylene-tetrahydrofolate cyclohydrolase [Tannerella sp. oral taxon BU063].	48.12	293	152	0	2	294	5	297	2e-101	311
rs:WP_046416452	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides sp. UNK.MGS-13].	51.37	292	142	0	4	295	2	293	2e-101	311
rs:WP_014856573	5,10-methylene-tetrahydrofolate dehydrogenase [Melioribacter roseus].	51.56	289	140	0	3	291	2	290	2e-101	311
rs:WP_014389106	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacterium indicum].	51.03	290	142	0	4	293	2	291	2e-101	311
rs:WP_009193871	hypothetical protein [Cesiribacter andamanensis].	51.38	290	141	0	5	294	9	298	3e-101	311
rs:WP_037985704	5,10-methylene-tetrahydrofolate cyclohydrolase [Tannerella sp. oral taxon BU063].	48.46	293	151	0	2	294	5	297	3e-101	311
rs:WP_005636475	5,10-methylene-tetrahydrofolate dehydrogenase [Parabacteroides merdae].	49.83	291	146	0	4	294	7	297	4e-101	310
rs:WP_005865864	MULTISPECIES: bifunctional protein FolD [Parabacteroides].	49.48	291	147	0	4	294	7	297	5e-101	310
rs:WP_036616904	5,10-methylene-tetrahydrofolate cyclohydrolase [Parabacteroides distasonis].	49.48	291	147	0	4	294	7	297	5e-101	310
rs:WP_008774102	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides sp. 2_1_33B].	49.48	291	147	0	4	294	7	297	5e-101	310
rs:WP_008861749	5,10-methylene-tetrahydrofolate dehydrogenase [Barnesiella intestinihominis].	51.03	292	143	0	4	295	2	293	6e-101	310
sp:FOLD_PARD8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.48	291	147	0	4	294	7	297	6e-101	310
rs:WP_035125902	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium aquatile].	50.69	288	142	0	4	291	2	289	7e-101	310
rs:WP_027389786	methenyltetrahydrofolate cyclohydrolase [Chrysiogenes arsenatis].	53.77	292	129	3	3	290	2	291	7e-101	310
rs:WP_022437568	bifunctional protein FolD [Prevotella sp. CAG:279].	49.14	291	148	0	4	294	2	292	8e-101	309
rs:WP_038336522	5,10-methylene-tetrahydrofolate cyclohydrolase [Empedobacter falsenii].	52.28	285	136	0	4	288	2	286	8e-101	309
rs:WP_024268146	methylenetetrahydrofolate dehydrogenase [Salinispira pacifica].	50.17	293	145	1	1	293	1	292	8e-101	309
rs:WP_005861634	MULTISPECIES: bifunctional protein FolD [Bacteroidales].	49.48	291	147	0	4	294	7	297	9e-101	309
rs:WP_019975599	5,10-methylene-tetrahydrofolate dehydrogenase [Empedobacter brevis].	51.93	285	137	0	4	288	2	286	9e-101	309
rs:WP_022321846	bifunctional protein FolD [Parabacteroides merdae CAG:48].	49.83	291	146	0	4	294	7	297	9e-101	309
tr:A0A069RWX9_9PORP	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.66	290	146	0	5	294	1	290	9e-101	309
rs:WP_027311336	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroidetes bacterium SCGC AAA027-N21].	51.39	288	140	0	4	291	2	289	1e-100	309
tr:A0A078T847_9PORP	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.66	290	146	0	5	294	1	290	1e-100	309
sp:FOLD_FLAPJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.92	287	138	0	5	291	3	289	1e-100	309
rs:WP_046410879	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides sp. N54.MGS-20].	51.03	292	143	0	4	295	2	293	1e-100	309
rs:WP_026981256	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium suncheonense].	51.93	285	137	0	4	288	2	286	1e-100	309
tr:A0A069S243_9PORP	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.66	290	146	0	5	294	1	290	1e-100	309
rs:WP_005646594	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Parabacteroides].	49.83	291	146	0	4	294	7	297	1e-100	309
rs:WP_022452978	bifunctional protein FolD [Prevotella sp. CAG:873].	51.37	292	142	0	4	295	2	293	1e-100	309
rs:WP_027392511	5,10-methylene-tetrahydrofolate cyclohydrolase [Aquimarina latercula].	51.04	288	141	0	4	291	2	289	1e-100	308
rs:WP_028981007	5,10-methylene-tetrahydrofolate cyclohydrolase [Sporocytophaga myxococcoides].	50.68	294	145	0	1	294	6	299	2e-100	309
rs:WP_019209079	5,10-methylene-tetrahydrofolate dehydrogenase [Phocaeicola abscessus].	50.68	292	144	0	4	295	2	293	2e-100	308
rs:WP_021311849	tetrahydrofolate dehydrogenase [Bacteroidetes bacterium oral taxon 272].	50.34	292	145	0	4	295	2	293	2e-100	308
rs:WP_020395402	hypothetical protein [Thiothrix disciformis].	53.74	294	126	2	1	294	1	284	3e-100	307
gpu:CP010904_1784	Bifunctional protein FolD protein [Verrucomicrobia bacterium L21-Fru-AB]	50.17	293	145	1	1	293	1	292	3e-100	308
rs:WP_022826927	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacterium antarcticum].	50.34	290	144	0	5	294	3	292	4e-100	308
rs:WP_018278908	5,10-methylene-tetrahydrofolate dehydrogenase [Capnocytophaga cynodegmi].	51.92	287	138	0	4	290	2	288	4e-100	307
rs:WP_013997583	5,10-methylene-tetrahydrofolate dehydrogenase [Capnocytophaga canimorsus].	50.87	287	141	0	4	290	2	288	4e-100	307
rs:WP_040248687	5,10-methylene-tetrahydrofolate cyclohydrolase [Psychroserpens mesophilus].	51.21	289	141	0	5	293	3	291	5e-100	307
rs:WP_006745584	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroides coprosuis].	50.00	290	145	0	5	294	3	292	5e-100	307
rs:WP_008154925	5,10-methylene-tetrahydrofolate dehydrogenase [Parabacteroides johnsonii].	49.48	291	147	0	4	294	7	297	5e-100	307
rs:WP_026977582	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium tegetincola].	50.17	287	143	0	5	291	3	289	6e-100	307
rs:WP_035130087	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium beibuense].	50.69	288	142	0	4	291	2	289	6e-100	307
rs:WP_038238292	5,10-methylene-tetrahydrofolate cyclohydrolase [Zobellia uliginosa].	50.35	288	143	0	5	292	3	290	7e-100	307
rs:WP_022160518	bifunctional protein FolD [Odoribacter splanchnicus CAG:14].	50.87	287	141	0	4	290	2	288	7e-100	307
rs:WP_008867542	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacteria bacterium MS024-3C].	51.74	288	139	0	4	291	2	289	8e-100	307
rs:WP_026464703	5,10-methylene-tetrahydrofolate cyclohydrolase [Adhaeribacter aquaticus].	49.14	291	148	0	4	294	2	292	8e-100	306
rs:WP_020213624	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacterium rivuli].	51.93	285	136	1	4	288	2	285	9e-100	306
rs:WP_022456252	bifunctional protein FolD [Parabacteroides sp. CAG:409].	49.66	294	148	0	1	294	1	294	9e-100	306
rs:WP_046403292	5,10-methylene-tetrahydrofolate cyclohydrolase [Odoribacter sp. UNK.MGS-12].	50.87	287	141	0	4	290	5	291	1e-99	306
rs:WP_015782831	5,10-methylene-tetrahydrofolate dehydrogenase [Capnocytophaga ochracea].	51.40	286	139	0	5	290	3	288	1e-99	306
rs:WP_009419904	tetrahydrofolate dehydrogenase [Capnocytophaga sp. oral taxon 380].	51.40	286	139	0	5	290	3	288	1e-99	306
rs:WP_041986694	5,10-methylene-tetrahydrofolate cyclohydrolase [Capnocytophaga canimorsus].	50.52	287	142	0	4	290	2	288	1e-99	306
rs:WP_002671629	5,10-methylene-tetrahydrofolate dehydrogenase [Capnocytophaga ochracea].	51.40	286	139	0	5	290	3	288	1e-99	306
rs:WP_009411394	tetrahydrofolate dehydrogenase [Capnocytophaga sp. oral taxon 324].	51.40	286	139	0	5	290	3	288	2e-99	306
rs:WP_006801397	5,10-methylene-tetrahydrofolate dehydrogenase [Dysgonomonas gadei].	48.80	291	149	0	4	294	2	292	2e-99	306
rs:WP_016478742	FolD protein [Capnocytophaga sp. oral taxon 336].	51.40	286	139	0	5	290	3	288	2e-99	306
rs:WP_025741848	5,10-methylene-tetrahydrofolate cyclohydrolase [Aquimarina sp. SW150].	50.69	288	142	0	4	291	2	289	2e-99	306
rs:WP_010523321	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacteriaceae bacterium HQM9].	50.87	289	140	2	4	291	2	289	2e-99	306
rs:WP_009418347	5,10-methylene-tetrahydrofolate dehydrogenase [Capnocytophaga sp. oral taxon 335].	51.40	286	139	0	5	290	3	288	2e-99	305
rs:WP_009412250	tetrahydrofolate dehydrogenase [Capnocytophaga sp. oral taxon 326].	51.40	286	139	0	5	290	3	288	2e-99	305
tr:F9ZAM0_ODOSD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.87	287	141	0	4	290	2	288	2e-99	305
rs:WP_029968525	methenyltetrahydrofolate cyclohydrolase [Desulfonauticus sp. A7A].	53.29	289	124	3	5	293	3	280	3e-99	305
rs:WP_033960724	5,10-methylene-tetrahydrofolate cyclohydrolase [Psychroserpens sp. PAMC 27130].	50.17	289	144	0	5	293	3	291	3e-99	305
rs:WP_026727747	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium denitrificans].	50.52	287	142	0	4	290	2	288	3e-99	305
rs:WP_026211457	methenyltetrahydrofolate cyclohydrolase [Lewinella cohaerens].	50.52	291	144	0	4	294	2	292	3e-99	305
rs:WP_045469118	5,10-methylene-tetrahydrofolate cyclohydrolase [Sporocytophaga myxococcoides].	50.68	294	145	0	1	294	1	294	3e-99	305
rs:WP_041557033	5,10-methylene-tetrahydrofolate cyclohydrolase [Odoribacter splanchnicus].	50.87	287	141	0	4	290	5	291	3e-99	305
rs:WP_019537737	5,10-methylene-tetrahydrofolate dehydrogenase [Proteiniphilum acetatigenes].	49.83	291	146	0	4	294	2	292	3e-99	305
rs:WP_042000016	5,10-methylene-tetrahydrofolate cyclohydrolase [Capnocytophaga canimorsus].	50.52	287	142	0	4	290	2	288	4e-99	305
rs:WP_022836715	5,10-methylene-tetrahydrofolate dehydrogenase [Salisaeta longa].	50.87	289	140	1	3	291	2	288	4e-99	305
rs:WP_018478177	5,10-methylene-tetrahydrofolate dehydrogenase [Pontibacter roseus].	49.66	290	146	0	5	294	3	292	4e-99	305
rs:WP_026839601	5,10-methylene-tetrahydrofolate cyclohydrolase [Gillisia sp. JM1].	50.70	284	140	0	5	288	3	286	4e-99	305
rs:WP_006843813	5,10-methylene-tetrahydrofolate dehydrogenase [Dysgonomonas mossii].	49.14	291	148	0	4	294	2	292	4e-99	305
rs:XP_002115412	hypothetical protein TRIADDRAFT_50697 [Trichoplax adhaerens].	53.56	295	131	4	2	294	14	304	4e-99	305
rs:WP_046403957	5,10-methylene-tetrahydrofolate cyclohydrolase [Odoribacter sp. N15.MGS-14].	50.52	287	142	0	4	290	5	291	4e-99	305
rs:WP_015753995	5,10-methylene-tetrahydrofolate dehydrogenase [Robiginitalea biformata].	49.48	287	145	0	5	291	3	289	4e-99	305
rs:WP_027064785	5,10-methylene-tetrahydrofolate cyclohydrolase [Maribacter sp. Hel_I_7].	49.31	288	146	0	4	291	2	289	5e-99	305
rs:WP_036152216	5,10-methylene-tetrahydrofolate cyclohydrolase [Maribacter forsetii].	49.65	288	145	0	4	291	2	289	5e-99	305
rs:WP_031445072	5,10-methylene-tetrahydrofolate cyclohydrolase [Arenibacter algicola].	50.35	288	143	0	4	291	2	289	6e-99	305
rs:WP_045081089	5,10-methylene-tetrahydrofolate cyclohydrolase [Vitellibacter vladivostokensis].	51.57	287	139	0	5	291	3	289	6e-99	304
rs:WP_045754397	5,10-methylene-tetrahydrofolate cyclohydrolase [Sphingobacterium sp. PM2-P1-29].	49.49	293	146	2	4	295	2	293	7e-99	305
sp:FOLD_FLAJ1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	287	143	0	4	290	2	288	7e-99	304
rs:WP_026944673	5,10-methylene-tetrahydrofolate cyclohydrolase [Algoriphagus marincola].	50.34	290	144	0	5	294	4	293	7e-99	304
rs:WP_025279491	5,10-methylene-tetrahydrofolate cyclohydrolase [Barnesiella viscericola].	50.17	291	145	0	4	294	2	292	7e-99	304
rs:WP_026861823	methenyltetrahydrofolate cyclohydrolase [Idiomarina sediminum].	53.12	288	125	2	1	288	1	278	8e-99	304
rs:WP_045090052	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonadaceae bacterium ING2-E5B].	49.32	292	148	0	4	295	2	293	8e-99	304
rs:WP_042007929	5,10-methylene-tetrahydrofolate cyclohydrolase [Capnocytophaga canimorsus].	50.17	287	143	0	4	290	2	288	8e-99	304
rs:WP_035337588	5,10-methylene-tetrahydrofolate cyclohydrolase [Dokdonia sp. PRO95].	51.22	287	140	0	5	291	3	289	9e-99	304
rs:WP_026450447	5,10-methylene-tetrahydrofolate cyclohydrolase [Aequorivita capsosiphonis].	50.87	287	141	0	5	291	3	289	9e-99	304
rs:WP_026755477	5,10-methylene-tetrahydrofolate cyclohydrolase [Sediminibacter sp. Hel_I_10].	49.83	289	145	0	5	293	3	291	1e-98	304
rs:WP_013768123	5,10-methylene-tetrahydrofolate dehydrogenase [Haliscomenobacter hydrossis].	49.66	290	146	0	5	294	3	292	1e-98	304
rs:WP_015432433	bifunctional protein FolD [Bibersteinia trehalosi].	51.55	291	130	2	1	291	1	280	1e-98	303
rs:WP_039081187	methenyltetrahydrofolate cyclohydrolase [Gallibacterium anatis].	51.52	297	134	2	1	297	1	287	1e-98	303
rs:WP_018106831	hypothetical protein [Porphyromonas bennonis].	49.65	288	145	0	5	292	7	294	1e-98	304
rs:WP_039083484	methenyltetrahydrofolate cyclohydrolase [Gallibacterium anatis].	51.52	297	134	2	1	297	1	287	1e-98	303
rs:WP_021615566	tetrahydrofolate dehydrogenase [Aggregatibacter sp. oral taxon 458].	52.05	292	129	2	1	292	1	281	2e-98	303
rs:WP_042346091	5,10-methylene-tetrahydrofolate cyclohydrolase [Capnocytophaga canimorsus].	50.17	287	143	0	4	290	2	288	2e-98	303
rs:WP_026706908	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium frigidarium].	50.88	285	140	0	4	288	2	286	2e-98	303
tr:A0A0D3LKI9_9BACT	SubName: Full=5,10-methylenetetrahydrofolate dehydrogenase (Nadp+) methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:AHM62434.1};	50.00	292	146	0	3	294	7	298	2e-98	303
rs:WP_014163851	5,10-methylene-tetrahydrofolate dehydrogenase [Thermovirga lienii].	54.20	286	120	3	1	286	1	275	2e-98	303
rs:WP_013745259	methenyltetrahydrofolate cyclohydrolase [Gallibacterium anatis].	51.52	297	134	2	1	297	1	287	2e-98	303
rs:WP_035657642	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium sp. EM1321].	49.13	287	146	0	4	290	2	288	2e-98	303
rs:WP_034061824	5,10-methylene-tetrahydrofolate cyclohydrolase [Lacinutrix sp. PAMC 27137].	50.52	287	142	0	5	291	3	289	2e-98	303
rs:WP_039169513	methenyltetrahydrofolate cyclohydrolase [Gallibacterium anatis].	51.88	293	131	2	1	293	1	283	2e-98	303
rs:WP_034889354	5,10-methylene-tetrahydrofolate cyclohydrolase [Gillisia sp. Hel_I_29].	51.22	287	139	1	5	291	3	288	2e-98	303
rs:WP_038696965	5,10-methylene-tetrahydrofolate cyclohydrolase [Sphingobacterium sp. ML3W].	50.17	293	144	2	4	295	2	293	2e-98	303
rs:WP_007094922	5,10-methylene-tetrahydrofolate dehydrogenase [Kordia algicida].	49.83	287	144	0	5	291	3	289	2e-98	303
rs:WP_010179592	5,10-methylene-tetrahydrofolate dehydrogenase [Aquimarina agarilytica].	50.52	291	142	2	4	293	2	291	2e-98	303
tr:H7FM16_9FLAO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.97	290	148	0	4	293	5	294	2e-98	303
rs:WP_039146717	methenyltetrahydrofolate cyclohydrolase [Gallibacterium anatis].	51.52	297	134	2	1	297	1	287	2e-98	303
rs:WP_040473573	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium frigoris].	48.97	290	148	0	4	293	2	291	3e-98	303
rs:WP_010853949	methylenetetrahydrofolate dehydrogenase [Cyclobacteriaceae bacterium AK24].	51.37	292	142	0	3	294	2	293	3e-98	303
rs:WP_026812232	5,10-methylene-tetrahydrofolate cyclohydrolase [Arenibacter certesii].	50.35	288	143	0	4	291	2	289	3e-98	303
rs:WP_009135372	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Odoribacter].	47.74	287	150	0	4	290	5	291	3e-98	303
rs:WP_039086780	methenyltetrahydrofolate cyclohydrolase [Gallibacterium anatis].	51.52	297	134	2	1	297	1	287	3e-98	302
rs:WP_021462406	methenyltetrahydrofolate cyclohydrolase [Gallibacterium anatis].	51.18	297	135	2	1	297	1	287	3e-98	302
rs:WP_044399361	5,10-methylene-tetrahydrofolate cyclohydrolase [Lacinutrix sp. Hel_I_90].	50.52	287	142	0	5	291	3	289	3e-98	303
rs:WP_008464511	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacterium sp. F52].	49.83	287	144	0	4	290	2	288	3e-98	303
rs:WP_039617947	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter lari].	53.10	290	123	4	5	293	3	280	4e-98	302
rs:WP_027414015	5,10-methylene-tetrahydrofolate cyclohydrolase [Aquimarina muelleri].	50.35	288	143	0	4	291	2	289	4e-98	303
rs:WP_009421102	5,10-methylene-tetrahydrofolate dehydrogenase [Capnocytophaga sp. oral taxon 412].	51.05	286	140	0	5	290	3	288	4e-98	302
rs:WP_047208121	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter lari].	53.10	290	123	4	5	293	3	280	4e-98	302
rs:WP_027126078	5,10-methylene-tetrahydrofolate cyclohydrolase [Gelidibacter mesophilus].	49.48	289	146	0	5	293	3	291	4e-98	302
rs:WP_013869008	5,10-methylene-tetrahydrofolate dehydrogenase [Lacinutrix sp. 5H-3-7-4].	50.17	287	143	0	5	291	3	289	5e-98	302
rs:WP_039136316	methenyltetrahydrofolate cyclohydrolase [Gallibacterium genomosp. 2].	51.85	297	133	2	1	297	1	287	5e-98	302
rs:WP_041570273	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter lari].	52.76	290	124	4	5	293	3	280	5e-98	301
rs:WP_035650704	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium sp. Fl].	50.17	287	143	0	4	290	2	288	5e-98	302
rs:WP_012674098	5,10-methylene-tetrahydrofolate dehydrogenase [Sulfurihydrogenibium azorense].	50.69	290	132	3	5	293	3	282	5e-98	301
rs:WP_034871748	5,10-methylene-tetrahydrofolate cyclohydrolase [Elizabethkingia miricola].	50.68	292	143	1	3	294	2	292	6e-98	302
rs:WP_024981285	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium succinicans].	49.13	287	146	0	4	290	2	288	6e-98	302
rs:WP_046672391	5,10-methylene-tetrahydrofolate cyclohydrolase [Sphingobacterium sp. Ag1].	48.11	291	151	0	5	295	3	293	6e-98	302
rs:WP_013993916	5,10-methylene-tetrahydrofolate dehydrogenase [Zobellia galactanivorans].	49.65	288	145	0	4	291	2	289	7e-98	302
rs:WP_026810420	5,10-methylene-tetrahydrofolate cyclohydrolase [Arenibacter latericius].	50.35	288	143	0	4	291	2	289	7e-98	302
tr:B9KFT0_CAMLR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	52.76	290	124	4	5	293	19	296	7e-98	302
rs:WP_019668244	5,10-methylene-tetrahydrofolate dehydrogenase [Eudoraea adriatica].	49.13	287	146	0	5	291	3	289	7e-98	302
rs:WP_028950237	5,10-methylene-tetrahydrofolate cyclohydrolase [Sulfurihydrogenibium subterraneum].	51.03	290	131	3	5	293	3	282	8e-98	301
rs:WP_007646539	methylenetetrahydrofolate dehydrogenase [Formosa sp. AK20].	51.41	284	138	0	5	288	3	286	8e-98	301
rs:WP_034924367	5,10-methylene-tetrahydrofolate cyclohydrolase [Gillisia sp. CAL575].	50.70	284	140	0	5	288	3	286	8e-98	301
rs:WP_028072408	5,10-methylene-tetrahydrofolate cyclohydrolase [Sphingobacterium thalpophilum].	48.80	291	149	0	5	295	3	293	9e-98	301
rs:WP_026704210	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium soli].	51.04	288	140	1	4	291	2	288	9e-98	301
rs:WP_036786767	5,10-methylene-tetrahydrofolate cyclohydrolase [Polaribacter sp. Hel1_33_49].	50.52	287	142	0	5	291	3	289	9e-98	301
rs:WP_039154751	methenyltetrahydrofolate cyclohydrolase [Gallibacterium anatis].	51.88	293	131	2	1	293	1	283	1e-97	301
rs:WP_038527446	5,10-methylene-tetrahydrofolate cyclohydrolase [Formosa agariphila].	50.52	287	142	0	5	291	3	289	1e-97	301
rs:WP_016169971	5,10-methylene-tetrahydrofolate dehydrogenase [Elizabethkingia meningoseptica].	51.03	292	142	1	3	294	2	292	1e-97	301
sp:FOLD_VIBF1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	54.30	291	123	3	1	291	1	281	1e-97	301
rs:WP_018355459	methenyltetrahydrofolate cyclohydrolase [Pasteurella pneumotropica].	51.54	293	131	2	1	293	1	282	1e-97	301
rs:WP_014938066	5,10-methylene-tetrahydrofolate dehydrogenase [Riemerella anatipestifer].	49.32	292	147	1	3	294	2	292	1e-97	301
rs:WP_004331097	5,10-methylene-tetrahydrofolate dehydrogenase [Porphyromonas asaccharolytica].	50.18	285	142	0	6	290	9	293	1e-97	301
rs:WP_013073225	5,10-methylene-tetrahydrofolate dehydrogenase [Zunongwangia profunda].	49.48	287	145	0	5	291	3	289	1e-97	301
rs:WP_044211159	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas asaccharolytica].	50.18	285	142	0	6	290	9	293	1e-97	301
rs:WP_005702174	methenyltetrahydrofolate cyclohydrolase [Aggregatibacter aphrophilus].	51.55	291	130	2	1	291	1	280	2e-97	300
rs:WP_007658144	5,10-methylene-tetrahydrofolate dehydrogenase [Pontibacter sp. BAB1700].	48.62	290	149	0	5	294	3	292	2e-97	301
rs:WP_009086773	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Elizabethkingia].	50.34	292	144	1	3	294	2	292	2e-97	301
rs:WP_013749544	5,10-methylene-tetrahydrofolate dehydrogenase [Dokdonia sp. 4H-3-7-5].	50.52	287	142	0	5	291	3	289	2e-97	301
rs:WP_015268333	5,10-methylene-tetrahydrofolate dehydrogenase [Echinicola vietnamensis].	50.17	291	145	0	5	295	4	294	2e-97	301
rs:WP_039625694	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter lari].	52.76	290	124	4	5	293	3	280	2e-97	300
rs:WP_009600620	methenyltetrahydrofolate cyclohydrolase [Vibrio caribbeanicus].	52.58	291	128	3	1	291	1	281	2e-97	300
rs:WP_013446910	5,10-methylene-tetrahydrofolate dehydrogenase [Riemerella anatipestifer].	49.32	292	147	1	3	294	2	292	2e-97	301
rs:WP_021778757	MULTISPECIES: bifunctional protein folD [Dokdonia].	50.52	287	142	0	5	291	3	289	2e-97	301
rs:WP_046745060	5,10-methylene-tetrahydrofolate cyclohydrolase [Kordia sp. MCCC 1A00726].	50.17	287	143	0	5	291	3	289	2e-97	301
rs:WP_026982844	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium sp. URHB0058].	49.83	287	144	0	4	290	2	288	2e-97	301
rs:WP_039641172	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter lari].	52.76	290	124	4	5	293	3	280	2e-97	300
rs:WP_032131797	5,10-methylene-tetrahydrofolate cyclohydrolase [Weeksella sp. FF8].	50.17	289	144	0	4	292	2	290	2e-97	300
rs:WP_007364955	5,10-methylene-tetrahydrofolate dehydrogenase [Porphyromonas uenonis].	49.82	285	143	0	6	290	9	293	2e-97	301
rs:WP_024567861	5,10-methylene-tetrahydrofolate cyclohydrolase [Elizabethkingia anophelis].	50.34	292	144	1	3	294	2	292	2e-97	300
rs:WP_046758326	5,10-methylene-tetrahydrofolate cyclohydrolase [Kordia jejudonensis].	49.13	287	146	0	5	291	3	289	3e-97	300
rs:WP_024283259	5,10-methylene-tetrahydrofolate cyclohydrolase [Algoriphagus marincola].	49.66	290	146	0	5	294	4	293	3e-97	300
rs:WP_041494916	5,10-methylene-tetrahydrofolate cyclohydrolase [Nonlabens marinus].	50.17	287	143	0	5	291	3	289	3e-97	300
rs:WP_009186113	5,10-methylene-tetrahydrofolate dehydrogenase [Cecembia lonarensis].	50.69	290	143	0	5	294	4	293	3e-97	300
rs:WP_045182929	5,10-methylene-tetrahydrofolate cyclohydrolase [Elizabethkingia sp. BM10].	50.34	292	144	1	3	294	2	292	3e-97	300
rs:WP_039165388	methenyltetrahydrofolate cyclohydrolase [Gallibacterium anatis].	51.18	297	135	2	1	297	1	287	4e-97	300
rs:WP_039158432	methenyltetrahydrofolate cyclohydrolase [Gallibacterium anatis].	51.54	293	132	2	1	293	1	283	4e-97	300
rs:WP_017731382	hypothetical protein [Nafulsella turpanensis].	49.32	294	149	0	1	294	1	294	4e-97	300
rs:WP_025883217	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas uenonis].	49.82	285	143	0	6	290	9	293	4e-97	300
rs:WP_013549413	5,10-methylene-tetrahydrofolate dehydrogenase [Cellulophaga algicola].	50.00	288	144	0	4	291	2	289	4e-97	300
tr:A6ERM7_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.17	287	143	0	5	291	3	289	4e-97	300
rs:WP_007548047	5,10-methylene-tetrahydrofolate dehydrogenase [Sulfurihydrogenibium yellowstonense].	51.74	288	128	3	5	291	3	280	4e-97	300
rs:WP_002535569	methylenetetrahydrofolate dehydrogenase [Grimontia indica].	52.92	291	127	2	1	291	1	281	4e-97	299
rs:WP_026933582	5,10-methylene-tetrahydrofolate cyclohydrolase [Gramella echinicola].	49.48	287	145	0	5	291	3	289	5e-97	300
rs:WP_004918265	5,10-methylene-tetrahydrofolate dehydrogenase [Riemerella anatipestifer].	48.97	292	148	1	3	294	2	292	5e-97	300
rs:WP_013666707	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobacterium sp. 21].	48.45	291	150	0	4	294	2	292	5e-97	300
rs:WP_013290817	5,10-methylene-tetrahydrofolate dehydrogenase [Caldicellulosiruptor obsidiansis].	54.98	291	118	5	1	288	1	281	5e-97	299
rs:WP_014216482	5,10-methylene-tetrahydrofolate dehydrogenase [Niastella koreensis].	51.05	286	140	0	4	289	2	287	5e-97	299
rs:WP_014084813	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacterium branchiophilum].	49.82	285	143	0	4	288	2	286	5e-97	300
rs:WP_028283907	5,10-methylene-tetrahydrofolate cyclohydrolase [Olleya marilimosa].	50.17	287	143	0	5	291	3	289	6e-97	300
rs:WP_007017035	methenyltetrahydrofolate cyclohydrolase [Bermanella marisrubri].	52.58	291	128	3	1	291	1	281	6e-97	299
rs:WP_035640873	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium sp. EM1308].	49.82	285	143	0	4	288	2	286	6e-97	299
rs:WP_031455923	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium chungangense].	49.83	287	144	0	4	290	2	288	6e-97	299
rs:WP_008627038	methenyltetrahydrofolate cyclohydrolase [Mariniradius saccharolyticus].	50.17	293	146	0	3	295	2	294	6e-97	299
rs:WP_010371140	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas].	53.95	291	124	3	1	291	1	281	6e-97	299
rs:WP_024821677	5,10-methylene-tetrahydrofolate cyclohydrolase [Aminobacterium mobile].	53.77	292	124	3	1	292	1	281	7e-97	299
rs:WP_026954688	5,10-methylene-tetrahydrofolate cyclohydrolase [Algoriphagus vanfongensis].	50.00	292	146	0	3	294	2	293	7e-97	299
rs:WP_035586973	5,10-methylene-tetrahydrofolate cyclohydrolase [Hippea jasoniae].	51.05	286	128	3	5	290	3	276	7e-97	299
rs:WP_008635038	5,10-methylene-tetrahydrofolate dehydrogenase [Bizionia argentinensis].	50.35	284	141	0	5	288	3	286	7e-97	299
rs:WP_013908775	5,10-methylene-tetrahydrofolate dehydrogenase [Thermodesulfatator indicus].	50.52	291	142	2	1	290	1	290	7e-97	300
rs:WP_018476091	5,10-methylene-tetrahydrofolate dehydrogenase [Echinicola pacifica].	50.69	290	143	0	5	294	4	293	7e-97	299
sp:FOLD_HAEPS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	295	136	2	1	295	1	284	7e-97	299
rs:WP_027176586	methenyltetrahydrofolate cyclohydrolase [Desulfovibrio aminophilus].	52.84	282	126	1	5	286	3	277	7e-97	299
rs:WP_035682262	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium reichenbachii].	49.13	287	146	0	4	290	2	288	7e-97	299
rs:WP_022405280	bifunctional protein FolD [Prevotella sp. CAG:485].	50.00	288	144	0	5	292	3	290	8e-97	299
rs:WP_013062265	5,10-methylene-tetrahydrofolate dehydrogenase [Salinibacter ruber].	51.74	288	136	2	3	290	7	291	8e-97	299
rs:WP_039668228	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter lari].	52.07	290	126	4	5	293	3	280	8e-97	298
rs:WP_024563950	5,10-methylene-tetrahydrofolate cyclohydrolase [Elizabethkingia anophelis].	50.00	292	145	1	3	294	2	292	9e-97	299
rs:WP_014165301	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacterium columnare].	50.00	290	145	0	4	293	2	291	9e-97	299
rs:WP_042722558	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium sp. B17].	50.00	292	145	1	3	294	2	292	9e-97	299
rs:WP_039663288	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter subantarcticus].	52.41	290	125	4	5	293	3	280	9e-97	298
tr:A0A086FAE8_9FLAO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.34	292	144	1	3	294	2	292	1e-96	299
rs:WP_029296321	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium hispalense].	50.34	292	144	1	3	294	2	292	1e-96	299
rs:WP_045174477	5,10-methylene-tetrahydrofolate cyclohydrolase [Caldicellulosiruptor sp. Wai35.B1].	54.30	291	120	5	1	288	1	281	1e-96	298
rs:WP_039628195	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter lari].	52.41	290	125	4	5	293	3	280	1e-96	298
sp:FOLD_SALRD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.74	288	136	2	3	290	7	291	1e-96	299
rs:WP_018338397	5,10-methylene-tetrahydrofolate dehydrogenase [Butyricimonas synergistica].	49.83	287	144	0	4	290	2	288	1e-96	298
rs:WP_017494881	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacterium sp. WG21].	48.78	287	147	0	4	290	2	288	1e-96	298
rs:WP_038439490	methenyltetrahydrofolate cyclohydrolase [Haemophilus influenzae].	52.08	288	127	2	1	288	1	277	1e-96	298
rs:WP_028289276	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Olleya].	49.83	287	144	0	5	291	3	289	1e-96	298
rs:WP_026713150	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium daejeonense].	49.13	287	146	0	4	290	2	288	1e-96	298
rs:WP_039173599	methenyltetrahydrofolate cyclohydrolase [Gallibacterium genomosp. 1].	51.19	293	133	2	1	293	1	283	1e-96	298
rs:WP_037319310	5,10-methylene-tetrahydrofolate cyclohydrolase [Salegentibacter sp. Hel_I_6].	49.48	287	145	0	5	291	3	289	1e-96	299
rs:WP_039370126	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium taiwanense].	50.34	292	144	1	3	294	2	292	1e-96	298
rs:WP_027880178	5,10-methylene-tetrahydrofolate cyclohydrolase [Mesoflavibacter zeaxanthinifaciens].	49.83	287	144	0	5	291	3	289	1e-96	298
rs:WP_028990393	methenyltetrahydrofolate cyclohydrolase [Thermithiobacillus tepidarius].	51.54	293	132	2	1	293	1	283	1e-96	298
rs:WP_022932000	5,10-methylene-tetrahydrofolate dehydrogenase [Treponema bryantii].	51.54	293	139	2	1	293	1	290	1e-96	298
rs:WP_045501463	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium sp. StRB126].	50.34	292	144	1	3	294	2	292	2e-96	298
rs:WP_042600580	methenyltetrahydrofolate cyclohydrolase [Haemophilus influenzae].	51.74	288	128	2	1	288	1	277	2e-96	298
rs:WP_006988509	5,10-methylene-tetrahydrofolate dehydrogenase [Gillisia limnaea].	50.35	284	141	0	5	288	3	286	2e-96	298
rs:WP_046303567	methenyltetrahydrofolate cyclohydrolase [Grimontia sp. AD028].	52.58	291	128	2	1	291	1	281	2e-96	298
rs:WP_034677661	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium formosense].	50.34	292	144	1	3	294	2	292	2e-96	298
rs:WP_045164914	5,10-methylene-tetrahydrofolate cyclohydrolase [Thermoanaerobacter cellulolyticus].	54.98	291	118	5	1	288	1	281	2e-96	298
rs:WP_007803943	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacterium sp. CF136].	49.13	287	146	0	4	290	2	288	2e-96	298
rs:WP_014781363	5,10-methylene-tetrahydrofolate dehydrogenase [Aequorivita sublithincola].	50.17	287	143	0	5	291	3	289	2e-96	298
rs:WP_008503960	5,10-methylene-tetrahydrofolate dehydrogenase [Mucilaginibacter paludis].	49.83	291	146	0	4	294	2	292	2e-96	298
rs:WP_014790004	5,10-methylene-tetrahydrofolate dehydrogenase [Ornithobacterium rhinotracheale].	50.00	286	142	1	6	291	4	288	2e-96	298
rs:WP_043622221	methenyltetrahydrofolate cyclohydrolase [Chromobacterium piscinae].	52.94	289	126	3	1	289	1	279	2e-96	298
rs:WP_013305149	5,10-methylene-tetrahydrofolate dehydrogenase [Maribacter sp. HTCC2170].	49.48	287	145	0	5	291	3	289	2e-96	298
rs:WP_005702916	methenyltetrahydrofolate cyclohydrolase [Aggregatibacter aphrophilus].	51.20	291	131	2	1	291	1	280	2e-96	298
rs:WP_040097596	methenyltetrahydrofolate cyclohydrolase [Aeromonas australiensis].	51.55	291	131	2	1	291	1	281	2e-96	298
rs:WP_013909203	5,10-methylene-tetrahydrofolate dehydrogenase [Thermodesulfobacterium geofontis].	50.86	291	141	2	1	290	1	290	2e-96	298
rs:WP_047097196	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium indologenes].	50.34	292	144	1	3	294	2	292	2e-96	298
rs:WP_014031966	5,10-methylene-tetrahydrofolate dehydrogenase [Muricauda ruestringensis].	48.61	288	148	0	4	291	2	289	2e-96	298
rs:WP_007419057	methenyltetrahydrofolate cyclohydrolase [Idiomarina sp. A28L].	52.43	288	127	2	3	290	7	284	2e-96	298
rs:WP_019597958	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodonellum psychrophilum].	51.03	290	142	0	5	294	4	293	3e-96	298
rs:WP_009033584	5,10-methylene-tetrahydrofolate dehydrogenase [Indibacter alkaliphilus].	49.66	290	146	0	5	294	4	293	3e-96	298
rs:WP_009415859	tetrahydrofolate dehydrogenase [Capnocytophaga sp. oral taxon 332].	50.70	284	140	0	5	288	3	286	3e-96	298
rs:WP_021987549	bifunctional protein FolD [Odoribacter sp. CAG:788].	48.78	287	147	0	4	290	2	288	3e-96	298
rs:WP_026778109	5,10-methylene-tetrahydrofolate cyclohydrolase [Polaribacter sp. Hel_I_88].	49.83	287	144	0	5	291	3	289	3e-96	298
rs:WP_031426069	5,10-methylene-tetrahydrofolate cyclohydrolase [Leeuwenhoekiella sp. MAR_2009_132].	48.08	287	149	0	5	291	3	289	3e-96	298
rs:WP_047246239	5,10-methylene-tetrahydrofolate cyclohydrolase [Maribacter thermophilus].	49.31	288	146	0	4	291	2	289	3e-96	298
rs:WP_005351199	methenyltetrahydrofolate cyclohydrolase [Aeromonas veronii].	51.55	291	131	2	1	291	1	281	3e-96	297
rs:WP_046218765	methenyltetrahydrofolate cyclohydrolase [Photobacterium halotolerans].	52.92	291	127	2	1	291	1	281	3e-96	297
rs:WP_039112389	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium sp. KMS].	49.13	287	146	0	4	290	2	288	3e-96	298
rs:WP_017014154	methenyltetrahydrofolate cyclohydrolase [Enterovibrio calviensis].	52.92	291	127	2	1	291	1	281	3e-96	297
rs:WP_005337113	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Aeromonas].	51.55	291	131	2	1	291	1	281	3e-96	297
rs:WP_039665314	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter volucris].	53.45	290	122	4	5	293	3	280	3e-96	297
rs:WP_012771785	methenyltetrahydrofolate cyclohydrolase [Aggregatibacter aphrophilus].	50.52	291	133	2	1	291	1	280	4e-96	297
rs:WP_010606722	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas flavipulchra].	53.61	291	125	3	1	291	1	281	4e-96	297
rs:WP_039764483	5,10-methylene-tetrahydrofolate cyclohydrolase [Caldicellulosiruptor sp. F32].	53.95	291	121	5	1	288	1	281	4e-96	297
rs:WP_039119855	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium sp. JRM].	49.13	287	146	0	4	290	2	288	4e-96	297
tr:F1KCJ1_HAEIF	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.39	288	129	2	1	288	1	277	4e-96	297
sp:FOLD_TOLAT	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	53.26	291	126	2	1	291	1	281	4e-96	297
rs:WP_029272192	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium sp. KJJ].	49.13	287	146	0	4	290	2	288	4e-96	297
rs:WP_013411732	5,10-methylene-tetrahydrofolate dehydrogenase [Caldicellulosiruptor owensensis].	53.95	291	121	5	1	288	1	281	5e-96	297
rs:WP_032844896	methenyltetrahydrofolate cyclohydrolase [Mannheimia haemolytica].	50.85	293	134	2	1	293	1	283	5e-96	297
rs:WP_017951815	hypothetical protein [Nitrospina sp. SCGC AAA288-L16].	52.60	289	126	2	5	293	3	280	5e-96	296
rs:WP_038206778	methenyltetrahydrofolate cyclohydrolase [Vibrio tubiashii].	52.92	291	127	3	1	291	1	281	5e-96	297
rs:WP_022846217	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfurobacterium sp. TC5-1].	51.38	290	128	3	3	290	2	280	5e-96	296
tr:F1KCH5_HAEIF	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.39	288	129	2	1	288	1	277	5e-96	296
rs:WP_024479390	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Cellulophaga].	50.18	285	142	0	4	288	2	286	5e-96	297
rs:WP_041722587	5,10-methylene-tetrahydrofolate cyclohydrolase [Caldicellulosiruptor saccharolyticus].	54.30	291	120	5	1	288	1	281	5e-96	297
rs:WP_041904356	hypothetical protein [Latescibacteria bacterium SCGC AAA252-B13].	49.15	293	148	1	1	293	1	292	5e-96	297
rs:WP_016562762	bifunctional protein FolD [Bacteroides sp. CAG:927].	48.11	291	151	0	5	295	2	292	5e-96	297
rs:WP_041519903	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium hibernum].	49.13	287	146	0	4	290	2	288	5e-96	297
rs:WP_041885053	5,10-methylene-tetrahydrofolate cyclohydrolase [Pedobacter sp. NL19].	48.63	292	150	0	4	295	2	293	5e-96	297
rs:WP_027078391	5,10-methylene-tetrahydrofolate cyclohydrolase [Maribacter antarcticus].	48.96	288	147	0	4	291	2	289	6e-96	297
rs:WP_005346435	methenyltetrahydrofolate cyclohydrolase [Aeromonas veronii].	51.55	291	131	2	1	291	1	281	6e-96	296
sp:FOLD_SULSY	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.03	290	131	3	5	293	3	282	6e-96	296
rs:WP_022480817	tetrahydrofolate dehydrogenase [Prevotella sp. CAG:891].	49.32	292	147	1	4	295	2	292	6e-96	297
rs:WP_044618015	methenyltetrahydrofolate cyclohydrolase [Gynuella sunshinyii].	51.85	297	133	2	1	297	1	287	6e-96	296
tr:F4KMF0_PORAD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.18	285	142	0	6	290	75	359	6e-96	299
rs:WP_021714998	MULTISPECIES: bifunctional protein FolD [Vibrio].	52.05	292	130	3	1	292	1	282	6e-96	296
rs:WP_038019462	methenyltetrahydrofolate cyclohydrolase [Tatumella morbirosei].	52.23	291	129	2	1	291	1	281	6e-96	296
rs:WP_027378825	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium daeguense].	50.00	292	145	1	3	294	2	292	6e-96	297
rs:WP_017008455	methenyltetrahydrofolate cyclohydrolase [Enterovibrio calviensis].	52.92	291	127	2	1	291	1	281	6e-96	296
rs:WP_027386938	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium gregarium].	50.34	292	144	1	3	294	2	292	7e-96	296
rs:WP_034773812	methenyltetrahydrofolate cyclohydrolase [Idiomarina salinarum].	52.25	289	128	2	1	289	1	279	7e-96	296
tr:D0EMB9_HAEIF	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.39	288	129	2	1	288	1	277	7e-96	296
rs:WP_034692667	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium sp. CF365].	50.00	292	145	1	3	294	2	292	7e-96	296
rs:WP_013621751	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Cellulophaga].	48.96	288	147	0	4	291	2	289	8e-96	296
rs:WP_002678646	5,10-methylene-tetrahydrofolate dehydrogenase [Capnocytophaga sputigena].	50.00	286	143	0	5	290	3	288	8e-96	296
rs:WP_041504291	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [unclassified Porphyromonadaceae].	50.52	287	142	0	4	290	2	288	8e-96	296
rs:WP_028866107	methenyltetrahydrofolate cyclohydrolase [Psychromonas aquimarina].	53.26	291	126	3	1	291	1	281	8e-96	296
rs:WP_033138640	methenyltetrahydrofolate cyclohydrolase [Aeromonas sp. 4287D].	51.74	288	129	2	1	288	1	278	8e-96	296
rs:WP_025235725	methenyltetrahydrofolate cyclohydrolase [Mannheimia varigena].	50.00	296	138	2	1	296	1	286	8e-96	296
sp:FOLD_PHOPR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.23	291	129	3	1	291	1	281	8e-96	296
tr:E2PAE9_PASHA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.85	293	134	2	1	293	12	294	1e-95	296
rs:WP_026724555	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium sasangense].	50.35	288	143	0	4	291	2	289	1e-95	296
rs:WP_036793689	methenyltetrahydrofolate cyclohydrolase [Photobacterium phosphoreum].	52.58	291	128	3	1	291	1	281	1e-95	296
rs:WP_040080950	methenyltetrahydrofolate cyclohydrolase [Mannheimia haemolytica].	51.75	286	128	2	1	286	1	276	1e-95	296
rs:WP_042062215	methenyltetrahydrofolate cyclohydrolase [Aeromonas allosaccharophila].	51.55	291	131	2	1	291	1	281	1e-95	296
rs:WP_005636623	methenyltetrahydrofolate cyclohydrolase [Haemophilus haemolyticus].	52.43	288	126	2	1	288	1	277	1e-95	296
rs:WP_022090585	bifunctional protein FolD [Clostridium sp. CAG:492].	53.12	288	124	3	3	290	2	278	1e-95	296
rs:WP_046943076	methenyltetrahydrofolate cyclohydrolase [Haemophilus haemolyticus].	52.08	288	127	2	1	288	1	277	1e-95	296
tr:A4MX29_HAEIF	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.39	288	129	2	1	288	1	277	1e-95	296
rs:WP_045169294	5,10-methylene-tetrahydrofolate cyclohydrolase [Caldicellulosiruptor sp. Rt8.B8].	55.33	291	117	5	1	288	1	281	1e-95	296
rs:WP_027252855	methenyltetrahydrofolate cyclohydrolase [Photobacterium halotolerans].	52.58	291	128	2	1	291	1	281	1e-95	296
sp:FOLD2_COLP3	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.74	292	128	2	1	292	1	282	1e-95	296
rs:WP_027202732	5,10-methylene-tetrahydrofolate cyclohydrolase [Butyricimonas virosa].	49.83	287	144	0	4	290	2	288	1e-95	296
rs:WP_014064768	methenyltetrahydrofolate cyclohydrolase [Haemophilus parainfluenzae].	51.74	288	128	2	1	288	1	277	1e-95	296
rs:WP_014680190	5,10-methylene-tetrahydrofolate dehydrogenase [Solitalea canadensis].	48.45	291	150	0	4	294	2	292	1e-95	296
rs:WP_045102556	methenyltetrahydrofolate cyclohydrolase [Aliivibrio wodanis].	53.26	291	126	3	1	291	1	281	1e-95	296
rs:WP_013403622	5,10-methylene-tetrahydrofolate dehydrogenase [Caldicellulosiruptor hydrothermalis].	54.64	291	119	5	1	288	1	281	1e-95	296
rs:WP_026475579	5,10-methylene-tetrahydrofolate cyclohydrolase [Alkaliflexus imshenetskii].	48.45	291	150	0	4	294	2	292	1e-95	296
rs:WP_015360924	5,10-methylene-tetrahydrofolate dehydrogenase [Nonlabens dokdonensis].	49.48	287	145	0	5	291	3	289	1e-95	296
rs:WP_004395657	methenyltetrahydrofolate cyclohydrolase [Vibrio metschnikovii].	52.23	291	129	2	1	291	1	281	1e-95	296
rs:WP_027350721	methenyltetrahydrofolate cyclohydrolase [Halotalea alkalilenta].	49.66	290	136	2	1	290	1	280	1e-95	295
rs:WP_016411998	tetrahydrofolate dehydrogenase [Prevotella sp. CAG:1031].	49.31	290	147	0	4	293	2	291	1e-95	296
rs:WP_015907501	5,10-methylene-tetrahydrofolate dehydrogenase [Caldicellulosiruptor bescii].	54.64	291	119	5	1	288	1	281	2e-95	296
rs:WP_039979242	methenyltetrahydrofolate cyclohydrolase [Vibrio sagamiensis].	51.89	291	130	2	1	291	1	281	2e-95	295
rs:WP_040987911	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Vibrio].	51.20	291	132	2	1	291	1	281	2e-95	295
rs:WP_005715706	methenyltetrahydrofolate cyclohydrolase [Aggregatibacter segnis].	51.55	291	130	2	1	291	1	280	2e-95	295
tr:F1KCI3_HAEIF	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.39	288	129	2	1	288	1	277	2e-95	295
rs:WP_043019561	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter subantarcticus].	52.07	290	126	4	5	293	3	280	2e-95	295
rs:WP_047248268	methenyltetrahydrofolate cyclohydrolase [Chromobacterium subtsugae].	52.58	291	128	3	1	291	1	281	2e-95	295
rs:WP_047133505	methenyltetrahydrofolate cyclohydrolase [bacterium JGI-5].	50.17	289	144	0	1	289	1	289	2e-95	296
rs:WP_013538011	5,10-methylene-tetrahydrofolate dehydrogenase [Thermovibrio ammonificans].	51.19	293	130	3	3	293	2	283	2e-95	295
rs:WP_022408317	bifunctional protein FolD [Clostridium sp. CAG:354].	51.22	287	129	4	4	290	3	278	2e-95	295
rs:WP_023377889	methylenetetrahydrofolate dehydrogenase [Smithella sp. ME-1].	53.31	287	124	3	3	289	2	278	2e-95	295
tr:F1KCJ3_HAEIF	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.39	288	129	2	1	288	1	277	2e-95	295
rs:WP_009103111	5,10-methylene-tetrahydrofolate dehydrogenase [Treponema sp. JC4].	51.88	293	138	2	1	293	1	290	2e-95	295
rs:WP_045035704	methenyltetrahydrofolate cyclohydrolase [Photobacterium iliopiscarium].	52.92	291	127	3	1	291	1	281	2e-95	295
rs:WP_042080411	methenyltetrahydrofolate cyclohydrolase [Aeromonas veronii].	51.20	291	132	2	1	291	1	281	2e-95	295
rs:WP_008254159	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacteria bacterium BAL38].	50.00	288	144	0	4	291	2	289	2e-95	295
rs:WP_034686813	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium piperi].	49.66	292	146	1	3	294	2	292	2e-95	295
rs:WP_028293498	methenyltetrahydrofolate cyclohydrolase [Oceanobacter kriegii].	52.92	291	127	2	1	291	1	281	2e-95	295
rs:WP_029285592	5,10-methylene-tetrahydrofolate cyclohydrolase [Pedobacter sp. R20-19].	48.11	291	151	0	4	294	2	292	2e-95	295
rs:WP_021072332	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobacterium paucimobilis].	50.00	292	144	2	4	294	2	292	2e-95	295
rs:WP_009346842	5,10-methylene-tetrahydrofolate dehydrogenase [Alloprevotella rava].	49.48	291	146	1	4	294	2	291	2e-95	295
sp:FOLD_PHOPO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; AltName: Full=PPDC; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.58	291	128	3	1	291	1	281	2e-95	295
rs:WP_005668619	methenyltetrahydrofolate cyclohydrolase [Haemophilus influenzae].	51.39	288	129	2	1	288	1	277	2e-95	295
sp:FOLD_GRAFK	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.13	287	146	0	5	291	3	289	2e-95	295
rs:WP_008613514	5,10-methylene-tetrahydrofolate dehydrogenase [Joostella marina].	50.69	288	142	0	4	291	2	289	2e-95	295
rs:XP_008588221	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Galeopterus variegatus].	52.51	299	135	3	3	295	37	334	3e-95	297
rs:WP_039052967	5,10-methylene-tetrahydrofolate cyclohydrolase [Sphingobacterium sp. T2].	48.11	291	151	0	4	294	2	292	3e-95	295
rs:WP_018060339	5,10-methylene-tetrahydrofolate dehydrogenase [Sulfurovum sp. SCGC AAA036-F05].	52.43	288	127	2	4	291	2	279	3e-95	295
rs:XP_001943654	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Acyrthosiphon pisum].	51.17	299	139	3	1	293	23	320	3e-95	297
rs:WP_007525971	methenyltetrahydrofolate cyclohydrolase [Haemophilus sputorum].	51.19	293	133	2	1	293	1	283	3e-95	295
rs:WP_034755019	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium sp. OV259].	49.66	292	146	1	3	294	2	292	3e-95	295
rs:WP_010129377	methenyltetrahydrofolate cyclohydrolase [Haemophilus sputorum].	51.19	293	133	2	1	293	1	283	3e-95	295
rs:WP_045027675	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Photobacterium].	52.92	291	127	3	1	291	1	281	3e-95	295
rs:WP_043703524	methenyltetrahydrofolate cyclohydrolase [Tepidimonas taiwanensis].	52.05	292	129	3	1	292	1	281	3e-95	295
rs:WP_035619401	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium hydatis].	48.78	287	147	0	4	290	2	288	3e-95	295
rs:WP_034709303	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium soli].	50.00	292	145	1	3	294	2	292	3e-95	295
rs:WP_027728610	methenyltetrahydrofolate cyclohydrolase [Treponema sp. C6A8].	52.92	291	134	2	1	291	1	288	3e-95	295
rs:WP_036122203	5,10-methylene-tetrahydrofolate cyclohydrolase [Mangrovimonas yunxiaonensis].	49.13	289	147	0	5	293	3	291	3e-95	295
rs:WP_042565988	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium sp. MEB061].	49.13	287	146	0	4	290	2	288	3e-95	295
rs:WP_004748512	methenyltetrahydrofolate cyclohydrolase [Vibrio tubiashii].	52.58	291	128	3	1	291	1	281	3e-95	295
rs:WP_026904974	5,10-methylene-tetrahydrofolate cyclohydrolase [Pedobacter glucosidilyticus].	47.93	290	151	0	5	294	3	292	3e-95	295
rs:WP_031414330	5,10-methylene-tetrahydrofolate cyclohydrolase [Brevibacillus laterosporus].	50.51	293	133	3	1	293	1	281	3e-95	295
rs:WP_042657876	methenyltetrahydrofolate cyclohydrolase [Aeromonas allosaccharophila].	51.20	291	132	2	1	291	1	281	3e-95	295
rs:WP_007145949	methenyltetrahydrofolate cyclohydrolase [Methylophaga aminisulfidivorans].	51.03	290	132	3	1	290	1	280	3e-95	295
rs:WP_033564383	5,10-methylene-tetrahydrofolate cyclohydrolase [Sphingobacteriaceae bacterium DW12].	47.08	291	154	0	4	294	2	292	3e-95	295
rs:WP_013554064	5,10-methylene-tetrahydrofolate dehydrogenase [Nitratifractor salsuginis].	51.72	290	130	2	4	293	2	281	4e-95	295
rs:WP_008619545	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Paraprevotella].	48.45	291	149	1	4	294	2	291	4e-95	295
rs:WP_013598159	5,10-methylene-tetrahydrofolate dehydrogenase [Weeksella virosa].	49.13	289	147	0	4	292	2	290	4e-95	295
rs:WP_026915183	5,10-methylene-tetrahydrofolate cyclohydrolase [Gramella portivictoriae].	48.78	287	147	0	5	291	3	289	4e-95	295
rs:WP_013430642	5,10-methylene-tetrahydrofolate dehydrogenase [Caldicellulosiruptor kronotskyensis].	53.95	291	121	5	1	288	1	281	4e-95	295
rs:WP_005547874	methenyltetrahydrofolate cyclohydrolase [Aggregatibacter actinomycetemcomitans].	49.83	291	135	2	1	291	1	280	4e-95	295
rs:WP_005658581	bifunctional protein FolD [Haemophilus influenzae].	51.39	288	129	2	1	288	1	277	4e-95	294
rs:WP_007470108	methylenetetrahydrofolate dehydrogenase [Photobacterium sp. AK15].	52.58	291	128	3	1	291	1	281	4e-95	295
rs:WP_027382854	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium caeni].	49.32	292	147	1	3	294	2	292	4e-95	295
rs:WP_032125417	methenyltetrahydrofolate cyclohydrolase [Chlamydia sp. 'Diamant'].	48.98	294	145	3	5	297	2	291	4e-95	295
rs:WP_044513541	5,10-methylene-tetrahydrofolate cyclohydrolase [Hymenobacter sp. DG25B].	48.97	290	148	0	5	294	12	301	4e-95	295
rs:WP_034718404	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium antarcticum].	50.00	292	145	1	3	294	2	292	4e-95	295
rs:WP_037389846	5,10-methylene-tetrahydrofolate cyclohydrolase [Smithella sp. SCADC].	53.26	291	126	3	3	293	2	282	4e-95	295
rs:WP_021035577	bifunctional protein FolD [Haemophilus influenzae].	51.04	288	130	2	1	288	1	277	5e-95	294
tr:J9GNM5_9ZZZZ	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EJX09244.1};	47.26	292	153	1	4	295	2	292	5e-95	295
sp:FOLD_HAEI8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.39	288	129	2	1	288	1	277	5e-95	294
rs:WP_045953863	methenyltetrahydrofolate cyclohydrolase [Vibrio sp. S2757].	52.23	291	129	3	1	291	1	281	5e-95	294
rs:WP_021709671	bifunctional protein FolD [Vibrio azureus].	51.55	291	131	2	1	291	1	281	5e-95	294
rs:WP_036462904	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Myroides].	48.61	288	148	0	4	291	2	289	5e-95	295
rs:WP_042024001	methenyltetrahydrofolate cyclohydrolase [Aeromonas sobria].	51.20	291	132	2	1	291	1	281	5e-95	294
rs:WP_015701765	methenyltetrahydrofolate cyclohydrolase [Haemophilus influenzae].	51.39	288	129	2	1	288	1	277	5e-95	294
rs:WP_038987096	5,10-methylene-tetrahydrofolate cyclohydrolase [Myroides odoratimimus].	49.31	288	146	0	4	291	2	289	5e-95	295
rs:WP_020896639	methylenetetrahydrofolate dehydrogenase [Winogradskyella psychrotolerans].	49.48	287	144	1	5	291	3	288	5e-95	295
rs:WP_005643942	methenyltetrahydrofolate cyclohydrolase [Haemophilus haemolyticus].	51.74	288	128	2	1	288	1	277	5e-95	294
rs:WP_008199555	5,10-methylene-tetrahydrofolate dehydrogenase [Algoriphagus machipongonensis].	49.66	290	146	0	5	294	3	292	5e-95	294
rs:WP_008626073	5,10-methylene-tetrahydrofolate dehydrogenase [Paraprevotella xylaniphila].	48.62	290	148	1	5	294	3	291	5e-95	294
rs:WP_041994102	methenyltetrahydrofolate cyclohydrolase [Aeromonas bivalvium].	51.03	290	132	2	1	290	1	280	6e-95	294
rs:WP_027366372	methenyltetrahydrofolate cyclohydrolase [Desulfovibrio africanus].	51.03	290	133	3	4	293	2	282	6e-95	294
sp:FOLD_VIBVU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.58	291	128	3	1	291	1	281	6e-95	294
rs:WP_043577500	methenyltetrahydrofolate cyclohydrolase [Chromobacterium subtsugae].	52.58	291	128	3	1	291	1	281	6e-95	294
rs:WP_010446897	methenyltetrahydrofolate cyclohydrolase [Vibrio rotiferianus].	52.92	291	127	3	1	291	1	281	6e-95	294
rs:WP_006995375	bifunctional protein FolD [Haemophilus aegyptius].	51.04	288	130	2	1	288	1	277	6e-95	294
rs:WP_045468878	5,10-methylene-tetrahydrofolate cyclohydrolase [Winogradskyella sp. PG-2].	49.83	287	143	1	5	291	3	288	6e-95	294
rs:WP_014258672	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio africanus].	51.03	290	133	3	4	293	2	282	6e-95	294
rs:WP_008991110	5,10-methylene-tetrahydrofolate dehydrogenase [Galbibacter marinus].	51.39	288	140	0	4	291	2	289	6e-95	294
rs:WP_005633078	methenyltetrahydrofolate cyclohydrolase [Haemophilus haemolyticus].	51.74	288	128	2	1	288	1	277	6e-95	294
rs:WP_039110096	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium sp. AED].	47.93	290	151	0	4	293	2	291	6e-95	294
rs:WP_013186944	5,10-methylene-tetrahydrofolate dehydrogenase [Croceibacter atlanticus].	49.13	287	146	0	5	291	3	289	6e-95	294
rs:WP_010252610	5,10-methylene-tetrahydrofolate dehydrogenase [Myroides injenensis].	48.96	288	147	0	4	291	2	289	6e-95	294
rs:WP_018708515	hypothetical protein [Bacillus fordii].	51.54	293	131	4	1	293	1	282	6e-95	294
rs:WP_003343908	5,10-methylene-tetrahydrofolate dehydrogenase [Brevibacillus laterosporus].	50.17	293	134	3	1	293	1	281	7e-95	294
sp:FOLD_CHRVO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.80	286	125	3	1	286	1	276	7e-95	294
rs:WP_008078013	methenyltetrahydrofolate cyclohydrolase [Vibrio sinaloensis].	52.92	291	127	3	1	291	1	281	7e-95	294
rs:WP_017371544	methenyltetrahydrofolate cyclohydrolase [Enterobacteriaceae bacterium LSJC7].	52.58	291	128	3	1	291	1	281	7e-95	294
rs:WP_006880973	methenyltetrahydrofolate cyclohydrolase [Vibrio brasiliensis].	52.58	291	128	3	1	291	1	281	7e-95	294
rs:WP_036579514	5,10-methylene-tetrahydrofolate cyclohydrolase [Nonlabens ulvanivorans].	49.13	287	146	0	5	291	3	289	7e-95	294
rs:WP_010136654	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacteriaceae bacterium S85].	48.78	287	147	0	5	291	3	289	8e-95	294
rs:WP_040034227	bifunctional protein FolD [Haemophilus influenzae].	51.04	288	130	2	1	288	1	277	8e-95	293
rs:WP_005506453	methenyltetrahydrofolate cyclohydrolase [Grimontia hollisae].	52.23	291	129	2	1	291	1	281	8e-95	293
rs:WP_002983915	5,10-methylene-tetrahydrofolate dehydrogenase [Chryseobacterium gleum].	49.32	292	147	1	3	294	2	292	8e-95	294
rs:WP_017029469	methenyltetrahydrofolate cyclohydrolase [Vibrio breoganii].	50.17	291	135	2	1	291	1	281	8e-95	293
rs:WP_006795713	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacteria bacterium BBFL7].	49.48	287	145	0	5	291	3	289	9e-95	294
rs:WP_027372994	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium].	49.66	292	146	1	3	294	2	292	9e-95	294
rs:WP_042803941	methenyltetrahydrofolate cyclohydrolase [Mannheimia haemolytica].	49.32	296	140	2	1	296	1	286	9e-95	293
rs:WP_009388923	5,10-methylene-tetrahydrofolate dehydrogenase [Capnocytophaga sp. oral taxon 329].	49.30	286	145	0	5	290	3	288	9e-95	294
rs:WP_004403453	methenyltetrahydrofolate cyclohydrolase [Vibrio nigripulchritudo].	52.92	291	127	3	1	291	1	281	9e-95	293
tr:F1KCI1_HAEIF	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.04	288	130	2	1	288	1	277	9e-95	293
tr:F1KCI9_HAEIF	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.04	288	130	2	1	288	1	277	9e-95	293
rs:WP_027074871	methenyltetrahydrofolate cyclohydrolase [Mannheimia granulomatis].	49.66	296	139	2	1	296	1	286	9e-95	293
tr:K1HWB9_9FLAO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.61	288	148	0	4	291	21	308	1e-94	295
rs:WP_022851406	tetrahydrofolate dehydrogenase [Geovibrio sp. L21-Ace-BES].	51.70	294	130	4	1	293	1	283	1e-94	293
rs:WP_003337886	5,10-methylene-tetrahydrofolate dehydrogenase [Brevibacillus laterosporus].	50.17	293	134	3	1	293	1	281	1e-94	293
rs:WP_016961004	methenyltetrahydrofolate cyclohydrolase [Enterovibrio norvegicus].	52.58	291	128	2	1	291	1	281	1e-94	293
rs:WP_037384283	5,10-methylene-tetrahydrofolate cyclohydrolase [Smithella sp. SCADC].	53.79	290	124	3	3	292	2	281	1e-94	293
rs:WP_017017784	methenyltetrahydrofolate cyclohydrolase [Enterovibrio calviensis].	52.58	291	128	2	1	291	1	281	1e-94	293
rs:NP_001085223	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Xenopus laevis].	52.16	301	137	3	3	297	30	329	1e-94	295
rs:WP_025209766	5,10-methylene-tetrahydrofolate cyclohydrolase [Hippea sp. KM1].	51.75	286	126	3	5	290	3	276	1e-94	293
rs:WP_021627859	tetrahydrofolate dehydrogenase [Capnocytophaga sp. oral taxon 863].	49.83	289	143	1	4	292	2	288	1e-94	293
rs:WP_019613941	methenyltetrahydrofolate cyclohydrolase [Psychromonas ossibalaenae].	52.58	291	128	2	1	291	1	281	1e-94	293
rs:WP_006930869	5,10-methylene-tetrahydrofolate dehydrogenase [Caldithrix abyssi].	53.22	295	135	3	4	297	5	297	1e-94	294
rs:WP_040008922	5,10-methylene-tetrahydrofolate cyclohydrolase [Francisella sp. FSC1006].	50.69	288	130	3	5	291	3	279	1e-94	293
rs:WP_037355920	5,10-methylene-tetrahydrofolate cyclohydrolase [Schleiferia thermophila].	49.30	286	145	0	5	290	3	288	1e-94	293
tr:Q6IP36_XENLA	SubName: Full=MGC78982 protein {ECO:0000313|EMBL:AAH72082.1};	52.16	301	137	3	3	297	30	329	1e-94	295
rs:WP_022512007	bifunctional protein FolD [Prevotella sp. CAG:617].	47.77	291	151	1	4	294	2	291	1e-94	293
rs:WP_028024899	methenyltetrahydrofolate cyclohydrolase [Enterovibrio calviensis].	52.58	291	128	3	1	291	1	281	1e-94	293
rs:WP_022669735	5,10-methylene-tetrahydrofolate dehydrogenase [Hippea alviniae].	51.75	286	126	3	5	290	3	276	1e-94	293
rs:WP_018672586	5,10-methylene-tetrahydrofolate dehydrogenase [Brevibacillus laterosporus].	50.85	293	132	3	1	293	1	281	1e-94	293
rs:WP_042293952	5,10-methylene-tetrahydrofolate cyclohydrolase [Nonlabens ulvanivorans].	48.78	287	147	0	5	291	3	289	1e-94	293
rs:WP_035667846	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium sp. 83].	48.08	287	149	0	4	290	2	288	1e-94	293
rs:WP_018234029	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio thiocyanodenitrificans].	51.54	293	132	2	1	293	1	283	1e-94	293
rs:WP_042029223	methenyltetrahydrofolate cyclohydrolase [Aeromonas enteropelogenes].	51.72	290	130	2	1	290	1	280	1e-94	293
rs:WP_005712159	methenyltetrahydrofolate cyclohydrolase [Haemophilus parasuis].	49.15	295	139	2	1	295	1	284	1e-94	293
rs:WP_029275150	5,10-methylene-tetrahydrofolate cyclohydrolase [Pedobacter borealis].	47.59	290	152	0	5	294	16	305	1e-94	294
sp:FOLD_HISS2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.74	288	128	2	1	288	1	277	1e-94	293
rs:WP_037336296	methenyltetrahydrofolate cyclohydrolase [Salinisphaera hydrothermalis].	52.45	286	126	3	1	286	1	276	2e-94	293
rs:WP_005661537	bifunctional protein FolD [Haemophilus influenzae].	51.04	288	130	2	1	288	1	277	2e-94	293
rs:WP_013505691	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfurispirillum indicum].	51.72	290	134	3	5	290	4	291	2e-94	293
rs:WP_025280819	methenyltetrahydrofolate cyclohydrolase [Ectothiorhodospira haloalkaliphila].	51.37	292	132	2	1	292	1	282	2e-94	293
rs:WP_006249216	methenyltetrahydrofolate cyclohydrolase [Mannheimia haemolytica].	51.40	286	129	2	1	286	1	276	2e-94	293
tr:A0A061HZ57_CRIGR	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:ERE66276.1}; EC=3.5.4.9 {ECO:0000313|EMBL:ERE66276.1};	51.17	299	139	3	3	295	15	312	2e-94	294
rs:WP_035579197	methenyltetrahydrofolate cyclohydrolase [Halomonas sp. TG39a].	50.52	291	134	2	1	291	1	281	2e-94	293
rs:WP_039985725	methenyltetrahydrofolate cyclohydrolase [Vibrio owensii].	52.58	291	128	3	1	291	1	281	2e-94	293
rs:WP_005765179	methenyltetrahydrofolate cyclohydrolase [Pasteurella dagmatis].	50.17	293	135	2	1	293	1	282	2e-94	293
rs:WP_031383766	methenyltetrahydrofolate cyclohydrolase [Halomonas zincidurans].	50.86	291	133	2	1	291	1	281	2e-94	293
rs:WP_042011542	methenyltetrahydrofolate cyclohydrolase [Aeromonas fluvialis].	51.56	289	130	2	1	289	1	279	2e-94	293
rs:WP_037030348	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. HPB0071].	49.83	291	136	2	1	291	1	281	2e-94	293
rs:WP_005988490	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio africanus].	50.34	290	135	3	4	293	2	282	2e-94	293
rs:XP_005599956	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Equus caballus].	51.17	299	139	3	3	295	23	320	2e-94	294
rs:WP_025635762	bifunctional protein FolD [Vibrio parahaemolyticus].	52.23	291	129	3	1	291	1	281	2e-94	293
rs:WP_017188386	methenyltetrahydrofolate cyclohydrolase [Vibrio harveyi].	52.58	291	128	3	1	291	1	281	2e-94	293
tr:K2E2T9_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.20	291	127	4	3	292	2	278	2e-94	292
rs:WP_010634217	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Aeromonas].	51.72	290	130	2	1	290	1	280	2e-94	293
tr:F6QW38_HORSE	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000015200}; Flags: Fragment;	51.17	299	139	3	3	295	5	302	2e-94	294
rs:WP_020530736	hypothetical protein [Flexithrix dorotheae].	48.96	288	147	0	4	291	2	289	2e-94	293
rs:WP_006232981	methenyltetrahydrofolate cyclohydrolase [Photobacterium profundum].	52.23	291	129	3	1	291	1	281	2e-94	293
sp:FOLD_AERS4	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.72	290	130	2	1	290	1	280	2e-94	293
rs:WP_033093525	methenyltetrahydrofolate cyclohydrolase [Colwellia psychrerythraea].	52.05	292	130	2	1	292	1	282	2e-94	292
rs:WP_004340560	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella buccae].	48.28	290	149	1	5	294	3	291	2e-94	293
rs:WP_046939653	methenyltetrahydrofolate cyclohydrolase [Haemophilus haemolyticus].	51.39	288	129	2	1	288	1	277	2e-94	292
rs:WP_034963541	5,10-methylene-tetrahydrofolate cyclohydrolase [Epilithonimonas sp. FH1].	49.32	292	147	1	3	294	2	292	2e-94	293
rs:WP_046950298	methenyltetrahydrofolate cyclohydrolase [Haemophilus haemolyticus].	51.74	288	128	2	1	288	1	277	2e-94	292
rs:WP_005665105	methenyltetrahydrofolate cyclohydrolase [Haemophilus influenzae].	51.04	288	130	2	1	288	1	277	2e-94	292
rs:WP_034732668	methenyltetrahydrofolate cyclohydrolase [Idiomarina sp. MCCC 1A10513].	51.03	290	132	2	1	290	1	280	3e-94	292
rs:WP_005298253	methenyltetrahydrofolate cyclohydrolase [Photobacterium damselae].	52.23	291	129	3	1	291	1	281	3e-94	292
rs:WP_034726908	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium sp. JM1].	49.66	292	146	1	3	294	2	292	3e-94	293
rs:WP_039465466	methenyltetrahydrofolate cyclohydrolase [Vibrio navarrensis].	52.23	291	129	3	1	291	1	281	3e-94	292
rs:XP_001500773	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Equus caballus].	51.17	299	139	3	3	295	37	334	3e-94	295
rs:WP_026003862	methenyltetrahydrofolate cyclohydrolase [Pseudomonas luteola].	49.83	291	136	2	1	291	1	281	3e-94	292
rs:WP_042050951	bifunctional protein FolD [Aeromonas dhakensis].	51.72	290	130	2	1	290	1	280	3e-94	292
rs:WP_005300012	MULTISPECIES: bifunctional protein FolD [Aeromonas].	51.72	290	130	2	1	290	1	280	3e-94	292
sp:FOLD_PASMU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	293	135	3	1	293	1	282	3e-94	292
rs:WP_038512907	methenyltetrahydrofolate cyclohydrolase [Vibrio coralliilyticus].	52.23	291	129	3	1	291	1	281	3e-94	292
rs:WP_042032316	methenyltetrahydrofolate cyclohydrolase [Aeromonas jandaei].	51.55	291	131	2	1	291	1	281	3e-94	292
rs:WP_007412045	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella sp. MSX73].	48.28	290	149	1	5	294	3	291	3e-94	292
rs:WP_015030800	5,10-methylene-tetrahydrofolate dehydrogenase [Emticicia oligotrophica].	49.48	291	145	2	5	294	3	292	3e-94	292
rs:WP_046075252	methenyltetrahydrofolate cyclohydrolase [Salinivibrio sp. KP-1].	50.17	291	135	3	1	291	1	281	3e-94	292
rs:WP_006959385	methenyltetrahydrofolate cyclohydrolase [Vibrio coralliilyticus].	52.23	291	129	3	1	291	1	281	3e-94	292
rs:WP_044623907	methenyltetrahydrofolate cyclohydrolase [Photobacterium gaetbulicola].	52.58	291	128	3	1	291	1	281	3e-94	292
rs:WP_025146269	5,10-methylene-tetrahydrofolate cyclohydrolase [Sphingobacterium sp. H1ai].	47.42	291	153	0	4	294	2	292	3e-94	292
rs:WP_045790040	methenyltetrahydrofolate cyclohydrolase [Aeromonas hydrophila].	51.72	290	130	2	1	290	1	280	4e-94	292
rs:WP_029303256	methenyltetrahydrofolate cyclohydrolase [Aeromonas hydrophila].	52.07	290	129	2	1	290	1	280	4e-94	292
tr:A0A061Q9C0_9VIBR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	52.58	291	128	3	1	291	1	281	4e-94	292
rs:WP_021280042	methenyltetrahydrofolate cyclohydrolase [Mannheimia haemolytica].	51.40	286	129	2	1	286	1	276	4e-94	292
rs:WP_025247498	methenyltetrahydrofolate cyclohydrolase [Mannheimia varigena].	49.66	296	139	2	1	296	1	286	4e-94	292
rs:WP_046167971	methenyltetrahydrofolate cyclohydrolase [Chromobacterium vaccinii].	52.45	286	126	3	1	286	1	276	4e-94	292
rs:WP_028122015	5,10-methylene-tetrahydrofolate cyclohydrolase [Epilithonimonas tenax].	48.97	292	148	1	3	294	2	292	4e-94	292
rs:WP_034973579	5,10-methylene-tetrahydrofolate cyclohydrolase [Epilithonimonas lactis].	48.97	292	148	1	3	294	2	292	4e-94	292
rs:XP_009485603	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Pelecanus crispus].	51.84	299	137	3	3	295	3	300	4e-94	293
rs:WP_006256929	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Myroides].	49.65	288	145	0	4	291	2	289	4e-94	292
rs:WP_042076496	methenyltetrahydrofolate cyclohydrolase [Aeromonas sanarellii].	51.03	290	132	2	1	290	1	280	4e-94	292
rs:WP_042280318	5,10-methylene-tetrahydrofolate cyclohydrolase [Nonlabens sediminis].	49.13	287	146	0	5	291	3	289	4e-94	292
rs:WP_014797587	5,10-methylene-tetrahydrofolate dehydrogenase [Flexibacter litoralis].	48.26	288	149	0	4	291	2	289	4e-94	292
rs:WP_043760043	methenyltetrahydrofolate cyclohydrolase [Aeromonas taiwanensis].	50.69	290	133	2	1	290	1	280	4e-94	292
rs:WP_041154228	methenyltetrahydrofolate cyclohydrolase [Vibrio mytili].	52.58	291	128	3	1	291	1	281	4e-94	292
rs:WP_005473355	methenyltetrahydrofolate cyclohydrolase [Vibrio sp. 16].	52.23	291	129	3	1	291	1	281	4e-94	292
rs:WP_005630820	methenyltetrahydrofolate cyclohydrolase [Haemophilus haemolyticus].	51.74	288	128	3	1	288	1	277	4e-94	291
rs:WP_016646728	FolD protein [Campylobacter ureolyticus].	52.61	287	125	3	5	291	3	278	4e-94	292
rs:WP_009707194	bifunctional protein FolD [Vibrio sp. HENC-03].	52.58	291	128	3	1	291	1	281	4e-94	292
rs:WP_005549347	methenyltetrahydrofolate cyclohydrolase [Aggregatibacter actinomycetemcomitans].	49.48	291	136	2	1	291	1	280	4e-94	292
sp:FOLD_HAEIG	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.69	288	131	2	1	288	1	277	4e-94	291
rs:WP_027191667	methenyltetrahydrofolate cyclohydrolase [Desulfovibrio putealis].	53.33	285	126	2	4	288	2	279	4e-94	292
rs:WP_033115163	methenyltetrahydrofolate cyclohydrolase [Aeromonas sp. AE122].	51.20	291	132	2	1	291	1	281	4e-94	291
rs:WP_046155900	methenyltetrahydrofolate cyclohydrolase [Chromobacterium vaccinii].	52.45	286	126	3	1	286	1	276	4e-94	291
rs:WP_026990981	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium subsaxonicum].	51.93	285	137	0	4	288	2	286	5e-94	292
tr:N2JF14_9PSED	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.83	291	136	2	1	291	19	299	5e-94	292
sp:FOLD_HISS1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.04	288	130	2	1	288	1	277	5e-94	291
rs:XP_008062567	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Tarsius syrichta].	52.86	297	133	3	3	293	37	332	5e-94	294
rs:WP_025342782	methenyltetrahydrofolate cyclohydrolase [Mannheimia varigena].	49.66	296	139	2	1	296	1	286	5e-94	291
rs:WP_033081295	methenyltetrahydrofolate cyclohydrolase [Colwellia psychrerythraea].	52.05	292	130	2	1	292	1	282	5e-94	291
rs:WP_044799817	methenyltetrahydrofolate cyclohydrolase [Aeromonas hydrophila].	51.72	290	130	2	1	290	1	280	5e-94	291
rs:WP_018964907	5,10-methylene-tetrahydrofolate dehydrogenase [Porphyromonas gulae].	48.10	289	150	0	2	290	4	292	5e-94	292
rs:WP_004345784	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella buccae].	47.59	290	151	1	5	294	3	291	5e-94	292
sp:FOLD2_THICR	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.03	290	131	3	1	290	1	279	5e-94	291
rs:WP_016419602	hypothetical protein [Capnocytophaga granulosa].	50.52	289	141	1	4	292	2	288	5e-94	292
rs:WP_042069621	methenyltetrahydrofolate cyclohydrolase [Aeromonas enteropelogenes].	51.38	290	131	2	1	290	1	280	5e-94	291
rs:WP_043168397	methenyltetrahydrofolate cyclohydrolase [Aeromonas hydrophila].	51.72	290	130	2	1	290	1	280	5e-94	291
rs:WP_005578168	methenyltetrahydrofolate cyclohydrolase [Aggregatibacter actinomycetemcomitans].	49.83	291	135	2	1	291	1	280	5e-94	291
rs:WP_017032557	methenyltetrahydrofolate cyclohydrolase [Vibrio breoganii].	49.83	291	136	2	1	291	1	281	5e-94	291
rs:WP_017411050	bifunctional protein FolD [Aeromonas hydrophila].	51.72	290	130	2	1	290	1	280	5e-94	291
rs:WP_046333499	methenyltetrahydrofolate cyclohydrolase [Pasteurella multocida].	49.83	293	136	3	1	293	1	282	5e-94	291
rs:WP_016415258	methenyltetrahydrofolate cyclohydrolase [Halomonas anticariensis].	50.34	290	134	2	1	290	1	280	5e-94	291
rs:WP_038161037	methenyltetrahydrofolate cyclohydrolase [Vibrio sp. B183].	52.23	291	129	3	1	291	1	281	5e-94	291
rs:WP_005496041	bifunctional protein FolD [Vibrio parahaemolyticus].	51.89	291	130	3	1	291	1	281	5e-94	291
rs:WP_013432297	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Caldicellulosiruptor].	53.26	291	123	5	1	288	1	281	6e-94	291
sp:FOLD_VIBCB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.58	291	128	3	1	291	1	281	6e-94	291
rs:XP_003510079	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Cricetulus griseus].	51.17	299	139	3	3	295	37	334	6e-94	294
rs:WP_028841618	methenyltetrahydrofolate cyclohydrolase [Thermodesulfobacterium hveragerdense].	51.19	293	141	2	1	292	1	292	6e-94	292
rs:WP_018712714	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter ureolyticus].	52.96	287	124	3	5	291	3	278	6e-94	291
rs:XP_008539148	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Equus przewalskii].	50.84	299	140	3	3	295	37	334	6e-94	294
rs:WP_038964825	methenyltetrahydrofolate cyclohydrolase [Vibrio vulnificus].	52.23	291	129	3	1	291	1	281	6e-94	291
rs:XP_006905253	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Pteropus alecto].	52.20	295	134	3	3	291	37	330	6e-94	294
rs:WP_039430037	methenyltetrahydrofolate cyclohydrolase [Vibrio navarrensis].	52.23	291	129	3	1	291	1	281	6e-94	291
rs:WP_015025304	5,10-methylene-tetrahydrofolate dehydrogenase [Psychroflexus torquis].	50.35	284	141	0	5	288	3	286	6e-94	291
rs:WP_020196048	methenyltetrahydrofolate cyclohydrolase [Vibrio owensii].	52.23	291	129	3	1	291	1	281	6e-94	291
rs:WP_022157712	bifunctional protein FolD [Prevotella sp. CAG:520].	50.17	287	142	1	4	290	2	287	6e-94	291
sp:FOLD_CROS8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	54.17	288	122	3	1	288	1	278	6e-94	291
rs:WP_005382297	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Vibrio].	51.89	291	130	2	1	291	1	281	6e-94	291
rs:WP_021817653	methenyltetrahydrofolate cyclohydrolase [Halomonas sp. BJGMM-B45].	50.34	290	134	2	1	290	1	280	6e-94	291
rs:WP_005446463	bifunctional protein FolD [Vibrio harveyi].	52.58	291	128	3	1	291	1	281	6e-94	291
rs:WP_022311038	bifunctional protein FolD [Prevotella sp. CAG:474].	48.45	291	149	1	4	294	5	294	7e-94	291
rs:WP_014706285	methenyltetrahydrofolate cyclohydrolase [Methylophaga nitratireducenticrescens].	49.83	291	136	3	1	291	1	281	7e-94	291
rs:WP_029037162	5,10-methylene-tetrahydrofolate cyclohydrolase [Salinimicrobium xinjiangense].	47.72	285	149	0	4	288	2	286	7e-94	292
rs:WP_019277867	methenyltetrahydrofolate cyclohydrolase [Vibrio coralliilyticus].	51.89	291	130	3	1	291	1	281	7e-94	291
rs:WP_028486045	methenyltetrahydrofolate cyclohydrolase [Thiomicrospira chilensis].	50.69	290	132	3	1	290	1	279	7e-94	291
rs:WP_043851082	methenyltetrahydrofolate cyclohydrolase [Aeromonas sp. L_1B5_3].	51.20	291	132	2	1	291	1	281	7e-94	291
rs:WP_014269077	5,10-methylene-tetrahydrofolate dehydrogenase [Sphaerochaeta pleomorpha].	51.75	286	136	1	4	289	2	285	7e-94	291
rs:XP_009098214	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Serinus canaria].	50.84	299	140	3	3	295	32	329	7e-94	293
rs:WP_039467637	methenyltetrahydrofolate cyclohydrolase [Photobacterium gaetbulicola].	52.58	291	128	3	1	291	1	281	7e-94	291
rs:WP_042602204	methenyltetrahydrofolate cyclohydrolase [Vibrio harveyi].	52.58	291	128	3	1	291	1	281	8e-94	291
rs:WP_043612316	methenyltetrahydrofolate cyclohydrolase [Chromobacterium violaceum].	52.45	286	126	3	1	286	1	276	8e-94	291
sp:FOLD_AERHH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.38	290	131	2	1	290	1	280	8e-94	291
rs:WP_025733922	methenyltetrahydrofolate cyclohydrolase [Carnimonas nigrificans].	49.83	289	135	2	1	289	1	279	8e-94	291
rs:WP_035467561	5,10-methylene-tetrahydrofolate cyclohydrolase [Algoriphagus mannitolivorans].	48.62	290	149	0	5	294	3	292	8e-94	291
rs:WP_042869836	methenyltetrahydrofolate cyclohydrolase [Aeromonas piscicola].	51.38	290	131	2	1	290	1	280	8e-94	291
rs:WP_043135939	methenyltetrahydrofolate cyclohydrolase [Aeromonas salmonicida].	51.38	290	131	2	1	290	1	280	8e-94	291
rs:WP_010649249	methenyltetrahydrofolate cyclohydrolase [Vibrio campbellii].	52.23	291	129	3	1	291	1	281	8e-94	291
rs:WP_045524985	methenyltetrahydrofolate cyclohydrolase [Aeromonas hydrophila].	51.72	290	130	2	1	290	1	280	9e-94	291
rs:WP_023574182	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacterium enshiense].	50.69	290	143	0	4	293	2	291	9e-94	291
rs:WP_005529961	bifunctional protein FolD [Vibrio campbellii].	52.23	291	129	3	1	291	1	281	9e-94	291
rs:WP_040999522	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium oranimense].	49.32	292	147	1	3	294	2	292	9e-94	291
rs:WP_005752391	bifunctional protein FolD [Pasteurella multocida].	49.83	293	136	3	1	293	1	282	9e-94	291
rs:WP_014391440	methenyltetrahydrofolate cyclohydrolase [Pasteurella multocida].	49.83	293	136	3	1	293	1	282	9e-94	291
rs:WP_034701320	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium].	49.32	292	147	1	3	294	2	292	9e-94	291
rs:WP_007865396	methylenetetrahydrofolate dehydrogenase [Cronobacter sakazakii].	54.17	288	122	3	1	288	1	278	9e-94	291
rs:WP_016350451	5,10-methylene-tetrahydrofolate dehydrogenase [Aeromonas hydrophila].	51.72	290	130	2	1	290	1	280	9e-94	291
rs:WP_029035500	5,10-methylene-tetrahydrofolate cyclohydrolase [Salinimicrobium terrae].	48.24	284	147	0	5	288	3	286	9e-94	291
rs:WP_009696037	methenyltetrahydrofolate cyclohydrolase [Vibrio sp. HENC-01].	52.58	291	128	3	1	291	1	281	9e-94	291
rs:WP_002668134	5,10-methylene-tetrahydrofolate dehydrogenase [Capnocytophaga gingivalis].	49.48	289	144	1	4	292	2	288	9e-94	291
rs:WP_032989249	methenyltetrahydrofolate cyclohydrolase [Cronobacter sakazakii].	54.17	288	122	3	1	288	1	278	9e-94	291
rs:WP_039214576	bifunctional protein FolD [Aeromonas hydrophila].	51.72	290	130	2	1	290	1	280	9e-94	291
rs:WP_005396027	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Vibrio].	51.55	291	131	2	1	291	1	281	1e-93	291
rs:WP_005326697	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Aeromonas].	51.03	290	132	2	1	290	1	280	1e-93	291
rs:WP_019950105	hypothetical protein [Kushneria aurantia].	50.34	290	134	2	1	290	1	280	1e-93	291
rs:WP_032803398	methenyltetrahydrofolate cyclohydrolase [Haemophilus sp. oral taxon 851].	51.39	288	129	2	1	288	1	277	1e-93	291
tr:G3W395_SARHA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSHAP00000009900}; Flags: Fragment;	52.84	299	134	3	3	295	38	335	1e-93	293
rs:WP_036895780	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella sp. S7 MS 2].	48.80	291	148	1	4	294	2	291	1e-93	291
rs:WP_043556841	methenyltetrahydrofolate cyclohydrolase [Aeromonas bestiarum].	51.38	290	131	2	1	290	1	280	1e-93	291
rs:WP_026027655	methenyltetrahydrofolate cyclohydrolase [Vibrio ordalii].	51.89	291	130	3	1	291	1	281	1e-93	291
rs:WP_043133109	methenyltetrahydrofolate cyclohydrolase [Aeromonas media].	51.03	290	132	2	1	290	1	280	1e-93	291
rs:WP_042042858	methenyltetrahydrofolate cyclohydrolase [Aeromonas rivuli].	50.34	290	134	2	1	290	1	280	1e-93	291
rs:WP_031501277	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium haifense].	49.66	292	146	1	3	294	2	292	1e-93	291
rs:WP_009286677	MULTISPECIES: tetrahydrofolate dehydrogenase [Halomonas].	50.52	291	134	2	1	291	1	281	1e-93	291
rs:WP_039452485	5,10-methylene-tetrahydrofolate cyclohydrolase [Pedobacter glucosidilyticus].	47.24	290	153	0	5	294	3	292	1e-93	291
rs:WP_027959406	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Halomonas].	50.52	291	134	2	1	291	1	281	1e-93	291
rs:WP_038864234	methenyltetrahydrofolate cyclohydrolase [Cronobacter muytjensii].	54.17	288	122	3	1	288	1	278	1e-93	291
rs:WP_027697038	methenyltetrahydrofolate cyclohydrolase [Vibrio litoralis].	51.55	291	131	3	1	291	1	281	1e-93	291
rs:WP_039975596	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Vibrio].	52.23	291	129	3	1	291	1	281	1e-93	291
rs:XP_012396026	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Sarcophilus harrisii].	52.84	299	134	3	3	295	39	336	1e-93	293
rs:WP_034456755	methenyltetrahydrofolate cyclohydrolase [Buttiauxella agrestis].	53.61	291	125	3	1	291	1	281	1e-93	291
rs:WP_008238373	5,10-methylene-tetrahydrofolate dehydrogenase [Pedobacter sp. BAL39].	47.42	291	153	0	4	294	2	292	1e-93	291
tr:A0A090R6T3_9VIBR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.55	291	131	3	1	291	1	281	1e-93	291
rs:WP_018920060	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella oris].	49.48	291	146	1	4	294	2	291	1e-93	291
rs:WP_034493929	methenyltetrahydrofolate cyclohydrolase [Buttiauxella agrestis].	53.26	291	126	3	1	291	1	281	1e-93	291
rs:WP_036848731	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas sp. COT-108 OH1349].	47.57	288	151	0	4	291	12	299	1e-93	291
rs:XP_005533038	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Pseudopodoces humilis].	51.17	299	139	3	3	295	32	329	1e-93	292
rs:WP_043122379	methenyltetrahydrofolate cyclohydrolase [Aeromonas hydrophila].	51.38	290	131	2	1	290	1	280	1e-93	290
rs:WP_029388183	methenyltetrahydrofolate cyclohydrolase [Vibrio anguillarum].	51.89	291	130	3	1	291	1	281	1e-93	290
sp:FOLD_VIBTL	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.89	291	130	3	1	291	1	281	1e-93	290
rs:WP_042035387	methenyltetrahydrofolate cyclohydrolase [Aeromonas popoffii].	51.38	290	131	2	1	290	1	280	1e-93	290
rs:WP_021475695	methenyltetrahydrofolate cyclohydrolase [Pseudogulbenkiania ferrooxidans].	52.10	286	127	3	1	286	1	276	1e-93	290
tr:H1LNN3_9PAST	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.39	288	129	2	1	288	19	295	1e-93	291
rs:WP_010317168	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Vibrio].	51.89	291	130	3	1	291	1	281	1e-93	290
rs:WP_008269120	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacteriales bacterium ALC-1].	49.48	287	144	1	5	291	3	288	1e-93	291
rs:WP_014323080	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio desulfuricans].	52.60	289	129	3	5	293	3	283	1e-93	290
rs:WP_021699595	bifunctional protein FolD [Pseudomonas alcaligenes].	51.38	290	131	2	1	290	1	280	1e-93	290
rs:WP_018046879	hypothetical protein [Nitrospina sp. AB-629-B06].	52.10	286	126	2	5	290	3	277	1e-93	290
rs:WP_010628476	methenyltetrahydrofolate cyclohydrolase [Halomonas sp. KM-1].	49.83	291	136	2	1	291	1	281	1e-93	291
rs:WP_002439049	methenyltetrahydrofolate cyclohydrolase [Shimwellia blattae].	52.92	291	127	3	1	291	1	281	1e-93	290
rs:WP_009436327	tetrahydrofolate dehydrogenase [Prevotella sp. oral taxon 473].	49.15	295	147	2	1	294	1	293	1e-93	291
rs:WP_038879305	bifunctional protein FolD [Vibrio jasicida].	52.23	291	129	3	1	291	1	281	2e-93	290
rs:WP_025902194	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Tatumella].	51.89	291	130	2	1	291	1	281	2e-93	290
rs:WP_022793583	5,10-methylene-tetrahydrofolate dehydrogenase [Marinococcus halotolerans].	49.48	291	136	3	1	291	1	280	2e-93	290
rs:WP_038060483	methenyltetrahydrofolate cyclohydrolase [Thermodesulfobacterium commune].	51.19	293	141	2	1	292	1	292	2e-93	291
rs:WP_009641089	5,10-methylene-tetrahydrofolate dehydrogenase [Capnocytophaga sp. CM59].	51.21	289	139	1	4	292	2	288	2e-93	291
rs:WP_038191544	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Vibrio].	51.89	291	130	3	1	291	1	281	2e-93	290
rs:WP_007114197	methenyltetrahydrofolate cyclohydrolase [Halomonas boliviensis].	49.49	297	140	2	1	297	1	287	2e-93	290
rs:WP_039440104	methenyltetrahydrofolate cyclohydrolase [Vibrio navarrensis].	52.23	291	129	3	1	291	1	281	2e-93	290
rs:WP_036969836	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas lipolytica].	52.23	291	129	3	1	291	1	281	2e-93	290
rs:XP_011439166	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Crassostrea gigas].	51.52	297	137	3	1	291	30	325	2e-93	292
rs:WP_007842066	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Chryseobacterium].	49.32	292	147	1	3	294	2	292	2e-93	291
rs:WP_040241504	methenyltetrahydrofolate cyclohydrolase [Chromohalobacter japonicus].	52.41	290	128	2	1	290	1	280	2e-93	290
rs:WP_023004955	methenyltetrahydrofolate cyclohydrolase [Halomonas sp. PBN3].	51.56	289	130	2	1	289	1	279	2e-93	290
rs:WP_045975264	methenyltetrahydrofolate cyclohydrolase [Vibrio neptunius].	51.89	291	130	3	1	291	1	281	2e-93	290
rs:WP_003441205	methylenetetrahydrofolate dehydrogenase [Psychroflexus gondwanensis].	50.00	284	142	0	5	288	3	286	2e-93	290
rs:WP_021678405	tetrahydrofolate dehydrogenase [Porphyromonas gingivalis].	47.75	289	151	0	2	290	4	292	2e-93	291
rs:WP_031524438	methenyltetrahydrofolate cyclohydrolase [Cronobacter sp. 1383].	52.58	291	128	3	1	291	1	281	2e-93	290
rs:WP_025216969	methenyltetrahydrofolate cyclohydrolase [Mannheimia varigena].	49.32	296	140	2	1	296	1	286	2e-93	290
rs:WP_039446179	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas gulae].	47.75	289	151	0	2	290	4	292	2e-93	290
rs:WP_036952132	methenyltetrahydrofolate cyclohydrolase [Providencia alcalifaciens].	51.20	291	132	3	1	291	1	281	2e-93	290
tr:D0EMC2_HAEIF	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.69	288	131	2	1	288	1	277	2e-93	290
rs:WP_027001061	5,10-methylene-tetrahydrofolate cyclohydrolase [Flexibacter elegans].	49.48	287	143	2	5	290	3	288	2e-93	290
rs:WP_042497037	5,10-methylene-tetrahydrofolate cyclohydrolase [Algibacter lectus].	48.79	289	148	0	5	293	3	291	2e-93	290
rs:WP_030072896	methenyltetrahydrofolate cyclohydrolase [Halomonas alkaliantarctica].	49.83	291	136	2	1	291	1	281	2e-93	290
rs:WP_038178486	methenyltetrahydrofolate cyclohydrolase [Vibrio rhizosphaerae].	52.23	291	129	2	1	291	1	281	2e-93	290
rs:WP_017033981	methenyltetrahydrofolate cyclohydrolase [Vibrio genomosp. F10].	51.55	291	131	3	1	291	1	281	2e-93	290
rs:WP_009133950	5,10-methylene-tetrahydrofolate dehydrogenase [Alistipes indistinctus].	51.38	290	139	1	5	294	3	290	2e-93	290
rs:WP_022430924	bifunctional protein FolD [Prevotella stercorea CAG:629].	49.48	287	144	1	4	290	2	287	2e-93	290
rs:WP_036876517	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella oryzae].	49.48	291	146	1	4	294	2	291	2e-93	290
rs:WP_024951904	methenyltetrahydrofolate cyclohydrolase [Cobetia crustatorum].	51.38	290	131	3	1	290	1	280	2e-93	290
rs:WP_019176192	hypothetical protein [Methanomassiliicoccus luminyensis].	48.63	292	149	1	1	292	1	291	2e-93	290
rs:WP_045400858	methenyltetrahydrofolate cyclohydrolase [Vibrio sp. 090810a].	51.89	291	130	3	1	291	1	281	2e-93	290
tr:A0A0A5L9U5_AERHY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.72	290	130	2	1	290	1	280	2e-93	290
rs:NP_001086806	methylenetetrahydrofolate dehydrogenase 2 [Xenopus laevis].	52.16	301	137	3	3	297	30	329	2e-93	291
rs:WP_004586893	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pseudoalteromonas].	52.92	291	127	3	1	291	1	281	2e-93	290
rs:NP_001123716	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase precursor [Xenopus (Silurana) tropicalis].	51.83	301	138	3	3	297	30	329	2e-93	291
rs:WP_041216302	methenyltetrahydrofolate cyclohydrolase [Aeromonas hydrophila].	51.38	290	131	2	1	290	1	280	2e-93	290
rs:WP_045370504	methenyltetrahydrofolate cyclohydrolase [Vibrio campbellii].	52.23	291	129	3	1	291	1	281	2e-93	290
rs:WP_013885218	tetrahydrofolate dehydrogenase [Flexistipes sinusarabici].	50.35	288	132	2	3	290	2	278	2e-93	290
rs:XP_002734253	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Saccoglossus kowalevskii].	54.52	299	126	5	3	293	47	343	2e-93	292
rs:WP_017629535	methenyltetrahydrofolate cyclohydrolase [Vibrio splendidus].	51.89	291	130	3	1	291	1	281	3e-93	290
rs:WP_025876031	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella corporis].	46.26	294	157	1	1	294	1	293	3e-93	290
rs:WP_039417805	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas].	47.75	289	151	0	2	290	4	292	3e-93	290
rs:WP_035409935	methenyltetrahydrofolate cyclohydrolase [Chromohalobacter israelensis].	51.72	290	130	2	1	290	1	280	3e-93	290
rs:WP_016767505	methenyltetrahydrofolate cyclohydrolase [Vibrio cyclitrophicus].	51.55	291	131	3	1	291	1	281	3e-93	290
rs:WP_008239471	5,10-methylene-tetrahydrofolate dehydrogenase [Imtechella halotolerans].	49.82	285	143	0	4	288	2	286	3e-93	290
rs:WP_036982531	methenyltetrahydrofolate cyclohydrolase [Providencia alcalifaciens].	51.20	291	132	3	1	291	1	281	3e-93	290
rs:WP_013074790	5,10-methylene-tetrahydrofolate dehydrogenase [Kyrpidia tusciae].	51.20	291	131	2	1	291	1	280	3e-93	290
rs:XP_003413735	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Loxodonta africana].	52.54	295	133	3	3	291	37	330	3e-93	292
sp:FOLD_MOOTA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	53.61	291	124	3	1	291	1	280	3e-93	290
rs:WP_028298344	5,10-methylene-tetrahydrofolate cyclohydrolase [Olivibacter sitiensis].	45.89	292	158	0	4	295	2	293	3e-93	290
rs:WP_028908816	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella sp. AGR2160].	48.62	290	148	1	5	294	4	292	3e-93	290
rs:WP_045801154	5,10-methylene-tetrahydrofolate cyclohydrolase [Muricauda lutaonensis].	47.74	287	150	0	5	291	3	289	3e-93	290
rs:WP_041620295	5,10-methylene-tetrahydrofolate cyclohydrolase [Paludibacter propionicigenes].	48.28	290	150	0	5	294	8	297	3e-93	290
tr:E4T3T1_PALPW	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.28	290	150	0	5	294	4	293	3e-93	290
rs:XP_006505760	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Mus musculus].	51.17	299	139	3	3	295	18	315	3e-93	291
rs:WP_036961668	methenyltetrahydrofolate cyclohydrolase [Providencia alcalifaciens].	51.20	291	132	3	1	291	1	281	3e-93	290
rs:WP_029301173	methenyltetrahydrofolate cyclohydrolase [Aeromonas hydrophila].	51.38	290	131	2	1	290	1	280	3e-93	290
tr:K7FDN0_PELSI	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPSIP00000006140}; Flags: Fragment;	51.84	299	137	3	3	295	23	320	3e-93	291
rs:WP_021590240	tetrahydrofolate dehydrogenase [Prevotella baroniae].	47.59	290	151	1	5	294	3	291	3e-93	290
rs:WP_029938804	methenyltetrahydrofolate cyclohydrolase [Thiomicrospira sp. MA2-6].	50.52	291	133	3	1	291	1	280	3e-93	290
rs:WP_010674955	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Aeromonas].	50.34	290	134	2	1	290	1	280	3e-93	290
sp:FOLD_LARHH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.41	290	128	2	1	290	1	280	3e-93	290
rs:WP_004372164	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella oris].	49.14	291	147	1	4	294	2	291	3e-93	290
rs:WP_047009507	methenyltetrahydrofolate cyclohydrolase [Vibrio alginolyticus].	51.55	291	131	2	1	291	1	281	3e-93	290
rs:WP_016533474	5,10-methylene-tetrahydrofolate dehydrogenase [Pasteurella multocida].	49.83	293	136	3	1	293	1	282	3e-93	290
rs:WP_014028821	methenyltetrahydrofolate cyclohydrolase [Acidithiobacillus ferrivorans].	49.49	293	138	2	1	293	1	283	3e-93	290
rs:WP_002694605	5,10-methylene-tetrahydrofolate dehydrogenase [Microscilla marina].	47.40	289	152	0	6	294	4	292	3e-93	290
rs:WP_004378767	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella oris].	49.14	291	147	1	4	294	2	291	3e-93	290
rs:WP_017843111	hypothetical protein [Flavobacterium sp. MS220-5C].	50.35	288	143	0	4	291	2	289	3e-93	290
rs:WP_038133949	methenyltetrahydrofolate cyclohydrolase [Vibrio caribbeanicus].	51.55	291	131	3	1	291	1	281	3e-93	290
rs:WP_005559336	methenyltetrahydrofolate cyclohydrolase [Aggregatibacter actinomycetemcomitans].	49.83	291	135	2	1	291	1	280	3e-93	290
rs:WP_041207477	methenyltetrahydrofolate cyclohydrolase [Aeromonas jandaei].	51.20	291	132	2	1	291	1	281	3e-93	290
rs:WP_028788430	5,10-methylene-tetrahydrofolate cyclohydrolase [Terrimonas ferruginea].	51.05	286	140	0	4	289	2	287	4e-93	290
rs:XP_009683506	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Struthio camelus australis].	51.84	299	137	3	3	295	8	305	4e-93	290
rs:WP_019025748	methenyltetrahydrofolate cyclohydrolase [Colwellia piezophila].	51.03	292	133	2	1	292	1	282	4e-93	289
rs:WP_039842082	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Pedobacter agri].	46.55	290	155	0	5	294	1	290	4e-93	290
rs:WP_008483364	methenyltetrahydrofolate cyclohydrolase [Gallaecimonas xiamenensis].	53.26	291	126	3	1	291	1	281	4e-93	289
rs:WP_042652335	methenyltetrahydrofolate cyclohydrolase [Aeromonas encheleia].	51.03	290	132	2	1	290	1	280	4e-93	289
rs:WP_041150828	5,10-methylene-tetrahydrofolate cyclohydrolase [Sulfurovum sp. FS08-3].	49.83	287	134	2	4	290	2	278	4e-93	289
rs:WP_042845338	methenyltetrahydrofolate cyclohydrolase [Providencia rettgeri].	51.20	291	132	3	1	291	1	281	4e-93	289
rs:WP_026028637	methenyltetrahydrofolate cyclohydrolase [Vibrio ordalii].	51.55	291	131	3	1	291	1	281	4e-93	289
rs:WP_042066530	methenyltetrahydrofolate cyclohydrolase [Aeromonas hydrophila].	51.38	290	131	2	1	290	1	280	4e-93	289
rs:WP_005594575	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Vibrio].	50.86	291	133	3	1	291	1	281	4e-93	289
rs:WP_036862616	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas sp. COT-108 OH2963].	47.22	288	152	0	4	291	12	299	4e-93	290
rs:WP_038213501	methenyltetrahydrofolate cyclohydrolase [Vibrio variabilis].	51.55	291	131	3	1	291	1	281	4e-93	289
rs:WP_027962889	methenyltetrahydrofolate cyclohydrolase [Halomonas halodenitrificans].	51.21	289	131	2	1	289	1	279	4e-93	289
rs:WP_008221243	methenyltetrahydrofolate cyclohydrolase [Vibrionales bacterium SWAT-3].	51.89	291	130	3	1	291	1	281	4e-93	289
rs:WP_009606284	5,10-methylene-tetrahydrofolate dehydrogenase [Turicibacter sp. HGF1].	53.47	288	124	3	3	290	2	279	4e-93	289
rs:WP_028783167	5,10-methylene-tetrahydrofolate cyclohydrolase [Thalassobacillus devorans].	53.26	291	124	3	1	291	1	279	4e-93	289
rs:WP_009725360	methylenetetrahydrofolate dehydrogenase [Methylophaga lonarensis].	49.48	289	136	2	1	289	1	279	4e-93	289
sp:MTDC_MOUSE	RecName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; Includes: RecName: Full=NAD-dependent methylenetetrahydrofolate dehydrogenase; EC=1.5.1.15; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Flags: Precursor;	51.17	299	139	3	3	295	37	334	4e-93	291
rs:WP_009582115	methylenetetrahydrofolate dehydrogenase [Fulvivirga imtechensis].	51.03	290	139	1	2	291	4	290	4e-93	290
rs:WP_006660671	methenyltetrahydrofolate cyclohydrolase [Providencia alcalifaciens].	51.20	291	132	3	1	291	1	281	4e-93	289
rs:XP_005078376	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Mesocricetus auratus].	50.84	299	140	3	3	295	37	334	5e-93	291
rs:WP_032551891	methenyltetrahydrofolate cyclohydrolase [Vibrio fortis].	51.89	291	130	3	1	291	1	281	5e-93	289
rs:WP_014254669	5,10-methylene-tetrahydrofolate dehydrogenase [[Clostridium] clariflavum].	50.87	289	131	3	1	289	1	278	5e-93	289
rs:WP_017056435	methenyltetrahydrofolate cyclohydrolase [Vibrio kanaloae].	51.55	291	131	3	1	291	1	281	5e-93	289
rs:WP_005356048	5,10-methylene-tetrahydrofolate dehydrogenase [Aeromonas diversa].	50.86	291	133	2	1	291	1	281	5e-93	289
rs:WP_045993754	methenyltetrahydrofolate cyclohydrolase [Halomonas sp. S2151].	51.56	289	130	2	1	289	1	279	5e-93	289
rs:WP_018954196	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio sp. ALJ17].	50.17	293	136	2	1	293	1	283	5e-93	289
rs:WP_000126774	methenyltetrahydrofolate cyclohydrolase [Vibrio cholerae].	50.86	291	133	3	1	291	1	281	5e-93	289
rs:WP_010436868	methenyltetrahydrofolate cyclohydrolase [Vibrio cyclitrophicus].	51.55	291	131	3	1	291	1	281	5e-93	289
rs:WP_044002015	5,10-methylene-tetrahydrofolate cyclohydrolase [Hymenobacter swuensis].	48.11	291	151	0	5	295	12	302	5e-93	290
rs:WP_016798161	methenyltetrahydrofolate cyclohydrolase [Vibrio cyclitrophicus].	51.55	291	131	3	1	291	1	281	5e-93	289
rs:WP_035400688	methenyltetrahydrofolate cyclohydrolase [Chlorobium sp. GBChlB].	50.86	291	141	1	5	293	3	293	5e-93	289
rs:WP_045596746	methenyltetrahydrofolate cyclohydrolase [Vibrio vulnificus].	52.45	286	126	3	6	291	1	276	5e-93	289
rs:WP_014168945	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Enterobacter cloacae complex].	52.92	291	127	3	1	291	1	281	5e-93	289
rs:WP_004169059	tetrahydrofolate dehydrogenase [Erwinia amylovora].	51.37	292	132	3	1	292	1	282	5e-93	289
rs:WP_028855642	hypothetical protein [Psychrilyobacter atlanticus].	50.35	284	131	2	3	286	2	275	5e-93	289
rs:WP_012458103	5,10-methylene-tetrahydrofolate dehydrogenase [Porphyromonas gingivalis].	47.75	289	151	0	2	290	4	292	5e-93	290
rs:WP_026994954	5,10-methylene-tetrahydrofolate cyclohydrolase [Flectobacillus major].	47.42	291	153	0	4	294	2	292	5e-93	289
rs:WP_006815090	methenyltetrahydrofolate cyclohydrolase [Providencia rustigianii].	51.20	291	132	3	1	291	1	281	5e-93	289
rs:WP_038267052	5,10-methylene-tetrahydrofolate cyclohydrolase [[Clostridium] litorale].	52.08	288	127	2	4	291	2	278	5e-93	289
rs:WP_047046804	methenyltetrahydrofolate cyclohydrolase [Vibrio sp. CAIM 1540].	51.89	291	130	3	1	291	1	281	5e-93	289
rs:WP_026718050	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacterium gelidilacus].	50.17	287	143	0	5	291	3	289	5e-93	289
tr:U1DTK7_ENTGA	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:ERE64364.1}; Flags: Fragment;	51.39	288	130	2	3	290	1	278	5e-93	289
rs:WP_041141473	5,10-methylene-tetrahydrofolate cyclohydrolase [Sulfurovum sp. PC08-66].	49.83	287	134	2	4	290	2	278	5e-93	289
rs:WP_015476885	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas denitrificans].	50.34	290	134	2	1	290	1	280	5e-93	289
tr:F7YLU6_VIBA7	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.89	291	130	3	1	291	26	306	5e-93	290
rs:WP_024742178	5,10-methylene-tetrahydrofolate cyclohydrolase [Tenacibaculum maritimum].	50.17	289	144	0	5	293	3	291	5e-93	289
rs:WP_017095018	methenyltetrahydrofolate cyclohydrolase [Vibrio splendidus].	51.89	291	130	3	1	291	1	281	5e-93	289
rs:WP_021661750	tetrahydrofolate dehydrogenase [Porphyromonas gingivalis].	47.75	289	151	0	2	290	4	292	5e-93	289
rs:WP_022316205	MULTISPECIES: bifunctional protein FolD [Prevotella].	47.77	291	151	1	4	294	2	291	6e-93	289
rs:WP_044626612	5,10-methylene-tetrahydrofolate cyclohydrolase [Tamlana nanhaiensis].	49.13	287	146	0	5	291	3	289	6e-93	289
rs:WP_025577501	bifunctional protein FolD [Vibrio parahaemolyticus].	52.58	291	128	3	1	291	1	281	6e-93	289
rs:WP_016913793	methenyltetrahydrofolate cyclohydrolase [Halomonas stevensii].	50.52	291	134	2	1	291	1	281	6e-93	289
rs:WP_028497746	methenyltetrahydrofolate cyclohydrolase [Microvirgula aerodenitrificans].	51.71	292	131	2	1	292	1	282	6e-93	289
sp:FOLD_CHRSD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.72	290	130	2	1	290	1	280	6e-93	289
rs:WP_017062367	methenyltetrahydrofolate cyclohydrolase [Vibrio crassostreae].	51.89	291	130	3	1	291	1	281	6e-93	289
rs:WP_005007111	5,10-methylene-tetrahydrofolate dehydrogenase [Nitrospina gracilis].	52.80	286	124	2	5	290	3	277	6e-93	289
rs:WP_016899272	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas].	51.89	291	130	2	1	291	1	281	6e-93	289
rs:WP_032707567	methenyltetrahydrofolate cyclohydrolase [Enterobacter aerogenes].	52.92	291	127	3	1	291	1	281	6e-93	289
rs:WP_032638613	methenyltetrahydrofolate cyclohydrolase [Enterobacter cloacae].	53.26	291	126	3	1	291	1	281	6e-93	289
rs:WP_025880648	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella baroniae].	47.59	290	151	1	5	294	3	291	6e-93	289
rs:WP_040725503	methenyltetrahydrofolate cyclohydrolase [Thiomicrospira sp. Kp2].	49.83	291	135	3	1	291	1	280	6e-93	289
sp:FOLD_SHEON	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.52	291	134	2	1	291	1	281	6e-93	289
rs:XP_004620044	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Sorex araneus].	51.86	295	135	3	3	291	37	330	6e-93	291
rs:WP_037494708	5,10-methylene-tetrahydrofolate cyclohydrolase [Sphingobacterium sp. ACCC 05744].	48.11	291	149	2	5	294	3	292	6e-93	289
rs:WP_010428257	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Enterobacter].	52.92	291	127	3	1	291	1	281	7e-93	289
rs:WP_045546188	methenyltetrahydrofolate cyclohydrolase [Vibrio sp. S512-13].	52.23	291	129	3	1	291	1	281	7e-93	289
rs:WP_031821841	methenyltetrahydrofolate cyclohydrolase [Vibrio parahaemolyticus].	52.23	291	129	3	1	291	1	281	7e-93	289
rs:WP_020080838	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacterium sp. SCGC AAA160-P02].	49.48	287	143	2	5	290	3	288	7e-93	289
rs:WP_007897671	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella stercorea].	49.13	287	145	1	4	290	2	287	7e-93	289
rs:WP_039342027	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium solincola].	48.97	292	148	1	3	294	2	292	7e-93	289
rs:WP_022121927	bifunctional protein FolD [Prevotella copri CAG:164].	47.59	290	151	1	5	294	3	291	7e-93	289
rs:WP_012794495	5,10-methylene-tetrahydrofolate dehydrogenase [Chitinophaga pinensis].	47.93	290	151	0	4	293	2	291	7e-93	289
rs:WP_040556851	methenyltetrahydrofolate cyclohydrolase [Reinekea blandensis].	51.20	291	132	2	1	291	1	281	7e-93	289
rs:WP_000126773	bifunctional protein FolD [Vibrio cholerae].	50.86	291	133	3	1	291	1	281	7e-93	289
rs:WP_036817217	methenyltetrahydrofolate cyclohydrolase [Photobacterium sanctipauli].	51.89	291	130	3	1	291	1	281	7e-93	289
rs:XP_012380678	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Dasypus novemcinctus].	52.54	295	133	3	3	291	37	330	7e-93	291
rs:WP_000126779	bifunctional protein FolD [Vibrio cholerae].	50.86	291	133	3	1	291	1	281	7e-93	288
rs:XP_004369243	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Trichechus manatus latirostris].	52.20	295	134	3	3	291	37	330	8e-93	291
rs:WP_014810206	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfomonile tiedjei].	49.83	293	144	2	1	293	1	290	8e-93	289
rs:WP_020429941	methylenetetrahydrofolate dehydrogenase [Vibrio fluvialis].	51.20	291	132	3	1	291	1	281	8e-93	288
rs:WP_040975487	methenyltetrahydrofolate cyclohydrolase [Pasteurella sp. FF6].	49.48	291	136	2	1	291	1	280	8e-93	289
rs:WP_021020040	methenyltetrahydrofolate cyclohydrolase [Vibrio gazogenes].	51.89	291	130	2	1	291	1	281	8e-93	288
rs:WP_022855948	5,10-methylene-tetrahydrofolate dehydrogenase [Thermodesulfobacterium thermophilum].	50.85	293	142	2	1	292	1	292	8e-93	289
rs:WP_016535263	tetrahydrofolate dehydrogenase [Cedecea davisae].	52.58	291	128	3	1	291	1	281	8e-93	288
rs:WP_005696878	methenyltetrahydrofolate cyclohydrolase [Haemophilus parainfluenzae].	50.69	288	131	2	1	288	1	277	8e-93	288
rs:WP_017093162	methenyltetrahydrofolate cyclohydrolase [Vibrio splendidus].	51.55	291	131	3	1	291	1	281	8e-93	288
rs:WP_045381204	methenyltetrahydrofolate cyclohydrolase [Enterobacter aerogenes].	52.92	291	127	3	1	291	1	281	9e-93	288
rs:WP_013261728	methenyltetrahydrofolate cyclohydrolase [gamma proteobacterium HdN1].	50.17	289	134	2	1	289	1	279	9e-93	288
rs:WP_043992945	bifunctional protein FolD [Vibrio cholerae].	50.86	291	133	3	1	291	1	281	9e-93	288
rs:WP_014231181	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Vibrio].	51.55	291	131	3	1	291	1	281	9e-93	288
rs:WP_021677445	tetrahydrofolate dehydrogenase [Porphyromonas gingivalis].	47.40	289	152	0	2	290	4	292	9e-93	289
rs:WP_015367875	methenyltetrahydrofolate cyclohydrolase [Enterobacter aerogenes].	52.92	291	127	3	1	291	1	281	9e-93	288
rs:WP_004734180	methenyltetrahydrofolate cyclohydrolase [Vibrio splendidus].	51.55	291	131	3	1	291	1	281	9e-93	288
rs:WP_033132582	methenyltetrahydrofolate cyclohydrolase [Aeromonas sp. AE235].	50.69	290	133	2	1	290	1	280	9e-93	288
rs:WP_020449463	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Methanomassiliicoccus intestinalis].	48.97	292	148	1	1	292	1	291	9e-93	289
rs:WP_013815893	bifunctional protein FolD [Porphyromonas gingivalis].	47.75	289	151	0	2	290	4	292	9e-93	289
rs:WP_042504290	5,10-methylene-tetrahydrofolate cyclohydrolase [Algibacter lectus].	48.44	289	149	0	5	293	3	291	9e-93	288
rs:WP_037378898	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Smithella].	52.58	291	128	3	3	293	2	282	1e-92	288
rs:XP_010170510	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Caprimulgus carolinensis].	51.51	299	138	3	3	295	3	300	1e-92	289
rs:WP_004858880	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Enterobacteriaceae].	52.58	291	128	3	1	291	1	281	1e-92	288
rs:XP_004468044	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Dasypus novemcinctus].	52.54	295	133	3	3	291	37	330	1e-92	291
tr:C3J8F6_9PORP	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.39	291	156	0	4	294	3	293	1e-92	289
rs:WP_000126777	bifunctional protein FolD [Vibrio cholerae].	50.86	291	133	3	1	291	1	281	1e-92	288
rs:XP_005364719	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Microtus ochrogaster].	51.17	299	139	3	3	295	37	334	1e-92	291
rs:WP_006176986	methenyltetrahydrofolate cyclohydrolase [Enterobacter cancerogenus].	53.26	291	126	3	1	291	1	281	1e-92	288
rs:WP_017086785	methenyltetrahydrofolate cyclohydrolase [Vibrio splendidus].	51.55	291	131	3	1	291	1	281	1e-92	288
rs:WP_000126771	methenyltetrahydrofolate cyclohydrolase [Vibrio cholerae].	50.86	291	133	3	1	291	1	281	1e-92	288
rs:WP_037440727	methenyltetrahydrofolate cyclohydrolase [Shewanella sp. YQH10].	49.83	291	136	2	1	291	1	281	1e-92	288
rs:WP_008822691	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella histicola].	47.28	294	154	1	1	294	1	293	1e-92	288
rs:WP_008910226	5,10-methylene-tetrahydrofolate dehydrogenase [Providencia burhodogranariea].	51.89	291	130	3	1	291	1	281	1e-92	288
sp:FOLD_ALISL	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	53.95	291	124	3	1	291	1	281	1e-92	288
rs:WP_003083178	tetrahydrofolate dehydrogenase [Streptococcus porcinus].	50.87	289	132	2	5	293	4	282	1e-92	288
rs:WP_045371795	methenyltetrahydrofolate cyclohydrolase [Enterobacter asburiae].	52.92	291	127	3	1	291	1	281	1e-92	288
sp:FOLD_VIBC3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.86	291	133	3	1	291	1	281	1e-92	288
rs:WP_040369739	methenyltetrahydrofolate cyclohydrolase [Desulfovibrio piger].	51.41	284	131	1	5	288	3	279	1e-92	288
rs:WP_004922311	methenyltetrahydrofolate cyclohydrolase [Providencia stuartii].	51.55	291	131	3	1	291	1	281	1e-92	288
rs:WP_010694488	FolD protein [Treponema denticola].	50.68	292	141	2	1	292	1	289	1e-92	288
rs:WP_025789484	methenyltetrahydrofolate cyclohydrolase [Vibrio parahaemolyticus].	52.23	291	129	3	1	291	1	281	1e-92	288
tr:M7BK09_CHEMY	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:EMP28547.1}; Flags: Fragment;	52.54	295	133	3	3	291	8	301	1e-92	289
rs:XP_006994410	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Peromyscus maniculatus bairdii].	50.84	299	140	3	3	295	37	334	1e-92	290
rs:WP_020327859	methylenetetrahydrofolate dehydrogenase [Vibrio fluvialis].	51.20	291	132	3	1	291	1	281	1e-92	288
rs:WP_039420765	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas gulae].	47.75	289	151	0	2	290	4	292	1e-92	288
rs:XP_007067517	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Chelonia mydas].	52.54	295	133	3	3	291	35	328	1e-92	290
rs:WP_044066247	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella sp. P5-125].	47.77	291	151	1	4	294	2	291	1e-92	288
rs:WP_033369902	5,10-methylene-tetrahydrofolate cyclohydrolase [Hymenobacter norwichensis].	48.29	292	151	0	4	295	9	300	1e-92	289
rs:WP_040579951	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas endodontalis].	46.39	291	156	0	4	294	6	296	1e-92	288
rs:WP_020409389	methenyltetrahydrofolate cyclohydrolase [Hahella ganghwensis].	53.47	288	124	3	2	289	3	280	1e-92	288
rs:WP_009844246	methenyltetrahydrofolate cyclohydrolase [Vibrio sp. AND4].	51.55	291	131	3	1	291	1	281	1e-92	288
sp:FOLD_VIBPA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.23	291	129	3	1	291	1	281	1e-92	288
sp:FOLD_DESDA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.57	287	132	1	5	291	3	282	1e-92	288
tr:A0A084W180_9DIPT	SubName: Full=Bifunctional protein folD {ECO:0000313|EMBL:KFB43974.1};	52.20	295	134	3	3	291	2	295	1e-92	289
tr:A0A093I5T7_STRCA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFV86557.1}; Flags: Fragment;	52.20	295	134	3	3	291	4	297	1e-92	288
sp:FOLD_PORGI	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.75	289	151	0	2	290	4	292	1e-92	288
rs:WP_043085477	methenyltetrahydrofolate cyclohydrolase [Pluralibacter gergoviae].	52.92	291	127	3	1	291	1	281	1e-92	288
rs:WP_025838467	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas cangingivalis].	46.90	290	154	0	2	291	7	296	1e-92	289
rs:WP_034937475	methenyltetrahydrofolate cyclohydrolase [Erwinia mallotivora].	50.86	291	133	2	1	291	1	281	1e-92	288
rs:WP_027439211	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium AC2031].	53.31	287	125	3	3	289	2	279	1e-92	288
rs:WP_037439912	5,10-methylene-tetrahydrofolate cyclohydrolase [Sphingobacterium antarcticum].	46.05	291	157	0	4	294	2	292	1e-92	288
rs:WP_028780275	methenyltetrahydrofolate cyclohydrolase [Shewanella sp. 38A_GOM-205m].	51.20	291	132	3	1	291	1	281	1e-92	288
rs:WP_022578258	methenyltetrahydrofolate cyclohydrolase [Vibrio mimicus].	50.86	291	133	3	1	291	1	281	1e-92	288
rs:WP_042486060	methenyltetrahydrofolate cyclohydrolase [Vibrio diazotrophicus].	52.23	291	129	3	1	291	1	281	1e-92	288
rs:WP_021286507	5,10-methylene-tetrahydrofolate dehydrogenase [Sulfurimonas sp. AST-10].	51.57	287	129	3	4	290	2	278	1e-92	288
rs:WP_015491734	5,10-methylene-tetrahydrofolate dehydrogenase [Thermoplasmatales archaeon BRNA1].	49.83	291	145	1	1	291	1	290	1e-92	288
sp:FOLD_SULNB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.08	288	128	2	4	291	2	279	1e-92	288
rs:WP_004337714	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella bivia].	46.94	294	155	1	1	294	1	293	1e-92	288
rs:WP_000126769	methenyltetrahydrofolate cyclohydrolase [Vibrio cholerae].	50.52	291	134	3	1	291	1	281	1e-92	288
rs:WP_025842487	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas gingivicanis].	45.58	294	160	0	1	294	1	294	1e-92	288
rs:WP_027375894	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium palustre].	49.32	292	147	1	3	294	2	292	1e-92	288
rs:WP_031533542	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides].	46.74	291	154	1	4	294	2	291	1e-92	288
rs:WP_004156475	methenyltetrahydrofolate cyclohydrolase [Erwinia amylovora].	51.37	292	132	3	1	292	1	282	1e-92	288
rs:NP_001102868	bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Rattus norvegicus].	50.84	299	140	3	3	295	36	333	1e-92	290
rs:XP_010308426	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Balearica regulorum gibbericeps].	51.51	299	138	3	3	295	3	300	1e-92	289
rs:WP_028871162	5,10-methylene-tetrahydrofolate cyclohydrolase [Psychroserpens burtonensis].	50.52	289	143	0	5	293	3	291	2e-92	288
rs:WP_039178025	methenyltetrahydrofolate cyclohydrolase [Halomonas hydrothermalis].	50.17	291	135	2	1	291	1	281	2e-92	288
rs:WP_000126768	methenyltetrahydrofolate cyclohydrolase [Vibrio mimicus].	50.86	291	133	3	1	291	1	281	2e-92	288
rs:WP_040558374	methenyltetrahydrofolate cyclohydrolase [Kingella oralis].	50.34	290	134	2	1	290	1	280	2e-92	288
rs:WP_044598513	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter peloridis].	50.69	290	130	4	5	293	3	280	2e-92	288
rs:XP_010377532	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Rhinopithecus roxellana].	51.53	295	136	3	3	291	37	330	2e-92	290
rs:WP_007678458	methylenetetrahydrofolate dehydrogenase [Cronobacter condimenti].	53.47	288	124	3	1	288	1	278	2e-92	288
rs:WP_036866191	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella bivia].	46.94	294	155	1	1	294	1	293	2e-92	288
rs:WP_028012225	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Enterobacter].	52.92	291	127	3	1	291	1	281	2e-92	288
rs:WP_028470918	methenyltetrahydrofolate cyclohydrolase [Neptunomonas japonica].	50.00	292	136	2	1	292	1	282	2e-92	288
rs:XP_007623752	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Cricetulus griseus].	50.84	299	140	3	3	295	37	334	2e-92	290
rs:XP_011239547	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Mus musculus].	51.17	299	139	3	3	295	40	337	2e-92	290
rs:WP_038181618	methenyltetrahydrofolate cyclohydrolase [Xenorhabdus bovienii].	50.52	291	134	3	1	291	1	281	2e-92	288
rs:WP_045328445	methenyltetrahydrofolate cyclohydrolase [Enterobacter asburiae].	52.92	291	127	3	1	291	1	281	2e-92	288
rs:WP_007755817	MULTISPECIES: methylenetetrahydrofolate dehydrogenase [Cronobacter].	53.47	288	124	3	1	288	1	278	2e-92	288
rs:WP_032480958	methenyltetrahydrofolate cyclohydrolase [Vibrio cholerae].	50.86	291	133	3	1	291	1	281	2e-92	288
rs:XP_002424280	methylenetetrahydrofolate dehydrogenase, putative [Pediculus humanus corporis].	51.69	296	136	3	1	290	1	295	2e-92	288
rs:WP_008499332	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Enterobacter].	52.92	291	127	3	1	291	1	281	2e-92	288
rs:WP_013638046	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfurobacterium thermolithotrophum].	52.41	290	125	3	3	290	2	280	2e-92	288
rs:WP_026079132	methenyltetrahydrofolate cyclohydrolase [Pseudomonas nitroreducens].	50.00	290	135	2	1	290	1	280	2e-92	288
rs:WP_002673393	bifunctional protein FolD [Treponema denticola].	50.68	292	141	2	1	292	1	289	2e-92	288
rs:WP_017074532	methenyltetrahydrofolate cyclohydrolase [Vibrio splendidus].	51.55	291	131	3	1	291	1	281	2e-92	288
rs:WP_007241753	methenyltetrahydrofolate cyclohydrolase [Haemophilus pittmaniae].	50.00	288	133	2	1	288	1	277	2e-92	288
rs:WP_044126371	methenyltetrahydrofolate cyclohydrolase [Vibrio cholerae].	50.86	291	133	3	1	291	1	281	2e-92	288
rs:WP_042047519	methenyltetrahydrofolate cyclohydrolase [Aeromonas simiae].	50.86	291	133	2	1	291	1	281	2e-92	288
rs:WP_008111045	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas].	51.55	291	131	2	1	291	1	281	2e-92	288
tr:U3JBY6_FICAL	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFALP00000000290}; Flags: Fragment;	50.84	299	140	3	3	295	68	365	2e-92	291
rs:WP_041454471	methenyltetrahydrofolate cyclohydrolase [Anaerolinea thermophila].	50.00	294	141	2	1	292	1	290	2e-92	288
rs:XP_006129185	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Pelodiscus sinensis].	51.84	299	137	3	3	295	89	386	2e-92	291
rs:WP_024552727	methenyltetrahydrofolate cyclohydrolase [Cronobacter helveticus].	52.58	291	128	3	1	291	1	281	2e-92	288
rs:XP_009946275	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Leptosomus discolor].	51.17	299	139	3	3	295	3	300	2e-92	288
rs:WP_003007656	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobacterium spiritivorum].	49.66	292	145	2	4	294	2	292	2e-92	288
tr:Q3U8E7_MOUSE	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:BAE31071.1};	51.17	299	139	3	3	295	37	334	2e-92	290
tr:C4GFK5_9NEIS	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.34	290	134	2	1	290	13	292	2e-92	288
rs:WP_032973232	methenyltetrahydrofolate cyclohydrolase [Cronobacter malonaticus].	53.47	288	124	3	1	288	1	278	2e-92	288
rs:WP_014292004	methenyltetrahydrofolate cyclohydrolase [Oceanimonas sp. GK1].	50.52	291	134	2	1	291	1	281	2e-92	287
rs:WP_036866774	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas canoris].	46.53	288	154	0	4	291	12	299	2e-92	288
rs:WP_012987705	methenyltetrahydrofolate cyclohydrolase [Xenorhabdus bovienii].	50.52	291	134	3	1	291	1	281	2e-92	288
rs:WP_047042357	methenyltetrahydrofolate cyclohydrolase [Enterobacter aerogenes].	52.92	291	127	3	1	291	1	281	2e-92	288
rs:WP_045969054	methenyltetrahydrofolate cyclohydrolase [Xenorhabdus doucetiae].	50.52	291	134	3	1	291	1	281	2e-92	288
rs:WP_039196414	methenyltetrahydrofolate cyclohydrolase [Actinobacillus equuli].	51.39	288	129	2	1	288	1	277	2e-92	287
rs:WP_036851414	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas cangingivalis].	47.22	288	152	0	4	291	9	296	2e-92	288
rs:WP_039483144	5,10-methylene-tetrahydrofolate cyclohydrolase [Pedobacter kyungheensis].	46.74	291	155	0	4	294	2	292	2e-92	288
rs:WP_024989849	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella albensis].	48.11	291	150	1	4	294	2	291	2e-92	288
rs:WP_037428154	methenyltetrahydrofolate cyclohydrolase [Shewanella sp. POL2].	50.52	291	134	2	1	291	1	281	2e-92	287
rs:WP_002858768	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter jejuni].	51.72	290	128	5	5	293	3	281	2e-92	287
rs:XP_009641709	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Egretta garzetta].	51.51	299	138	3	3	295	7	304	2e-92	288
rs:WP_002684557	bifunctional protein FolD [Treponema denticola].	50.68	292	141	2	1	292	1	289	2e-92	288
rs:WP_045095296	methenyltetrahydrofolate cyclohydrolase [Legionella fallonii].	48.98	294	140	2	1	294	1	284	2e-92	287
rs:WP_008243294	5,10-methylene-tetrahydrofolate dehydrogenase [Sulfurovum sp. AR].	51.57	287	129	2	4	290	2	278	2e-92	287
rs:WP_045509811	hypothetical protein [bacterium UASB14].	47.44	293	154	0	1	293	1	293	2e-92	288
rs:WP_044978398	methenyltetrahydrofolate cyclohydrolase [Treponema putidum].	51.37	292	139	2	1	292	1	289	2e-92	288
rs:WP_015780974	methenyltetrahydrofolate cyclohydrolase [Kangiella koreensis].	52.41	290	128	3	1	290	1	280	2e-92	287
rs:XP_005505302	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Columba livia].	51.17	299	139	3	3	295	30	327	2e-92	289
rs:WP_006847373	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella copri].	47.59	290	151	1	5	294	3	291	2e-92	288
rs:WP_013367259	methenyltetrahydrofolate cyclohydrolase [Enterobacter lignolyticus].	52.58	291	128	3	1	291	1	281	2e-92	287
rs:WP_004414778	methenyltetrahydrofolate cyclohydrolase [Vibrio orientalis].	52.23	291	129	3	1	291	1	281	2e-92	287
rs:WP_004737959	methenyltetrahydrofolate cyclohydrolase [Vibrio splendidus].	51.55	291	131	3	1	291	1	281	2e-92	287
tr:A0A0B8P535_9VIBR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.55	291	131	3	1	291	1	281	2e-92	287
rs:WP_004387140	methenyltetrahydrofolate cyclohydrolase [Cronobacter sakazakii].	53.47	288	124	3	1	288	1	278	2e-92	287
rs:WP_018361030	5,10-methylene-tetrahydrofolate dehydrogenase [Porphyromonas macacae].	46.69	287	153	0	4	290	9	295	3e-92	288
rs:WP_038032760	5,10-methylene-tetrahydrofolate cyclohydrolase [Thermonema rossianum].	47.93	290	151	0	5	294	3	292	3e-92	288
rs:XP_009807808	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Gavia stellata].	51.17	299	139	3	3	295	3	300	3e-92	288
rs:WP_023479064	bifunctional protein FolD [Enterobacter cloacae].	52.58	291	128	3	1	291	1	281	3e-92	287
rs:WP_016192214	5,10-methylene-tetrahydrofolate dehydrogenase [Erwinia tracheiphila].	51.20	291	132	2	1	291	1	281	3e-92	287
tr:D7HA01_VIBCL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.86	291	133	3	1	291	26	306	3e-92	288
sp:FOLD_NITSB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.74	288	128	2	4	291	2	278	3e-92	287
rs:WP_044017773	5,10-methylene-tetrahydrofolate cyclohydrolase [Hymenobacter sp. APR13].	48.11	291	151	0	5	295	12	302	3e-92	288
rs:WP_005629614	methenyltetrahydrofolate cyclohydrolase [Haemophilus haemolyticus].	50.35	288	132	2	1	288	1	277	3e-92	287
rs:WP_003001915	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobacterium spiritivorum].	49.66	292	145	2	4	294	2	292	3e-92	287
rs:WP_026627993	5,10-methylene-tetrahydrofolate cyclohydrolase [Dysgonomonas capnocytophagoides].	48.28	290	150	0	5	294	3	292	3e-92	287
rs:XP_005058053	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Ficedula albicollis].	50.84	299	140	3	3	295	80	377	3e-92	291
rs:WP_036894550	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella sp. S7-1-8].	47.28	294	154	1	1	294	1	293	3e-92	287
rs:WP_038238285	methenyltetrahydrofolate cyclohydrolase [Xenorhabdus szentirmaii].	50.52	291	134	3	1	291	1	281	3e-92	287
rs:WP_032457332	methenyltetrahydrofolate cyclohydrolase [Klebsiella pneumoniae].	52.58	291	128	3	1	291	1	281	3e-92	287
tr:C2HTD3_VIBAB	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.86	291	133	3	1	291	24	304	3e-92	288
rs:WP_002661703	5,10-methylene-tetrahydrofolate dehydrogenase [Bergeyella zoohelcum].	48.60	286	146	1	3	288	2	286	3e-92	287
rs:WP_040076827	methenyltetrahydrofolate cyclohydrolase [Enterobacteriaceae bacterium ATCC 29904].	52.58	291	128	3	1	291	1	281	3e-92	287
rs:WP_035192447	methenyltetrahydrofolate cyclohydrolase [Acidithiobacillus ferrivorans].	49.15	293	139	2	1	293	1	283	3e-92	287
rs:WP_018916090	methenyltetrahydrofolate cyclohydrolase [Halomonas zhanjiangensis].	49.14	291	138	2	1	291	1	281	3e-92	287
tr:A0A0B8Q0Z5_9VIBR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.55	291	131	3	1	291	1	281	3e-92	287
rs:WP_020561363	methenyltetrahydrofolate cyclohydrolase [Thiothrix flexilis].	51.86	295	131	4	1	294	1	285	3e-92	287
rs:XP_009073516	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Acanthisitta chloris].	50.84	299	140	3	3	295	3	300	3e-92	288
rs:WP_047365361	methenyltetrahydrofolate cyclohydrolase [Enterobacter sp. GN02457].	52.92	291	127	3	1	291	1	281	3e-92	287
rs:XP_005286565	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Chrysemys picta bellii].	52.19	297	135	3	3	293	43	338	3e-92	289
rs:WP_006253899	5,10-methylene-tetrahydrofolate dehydrogenase [Alloprevotella tannerae].	51.32	265	128	1	30	294	28	291	3e-92	287
rs:WP_043306862	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. ML96].	50.00	290	135	2	1	290	1	280	3e-92	287
sp:FOLD_TREDE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.68	292	141	2	1	292	1	289	3e-92	287
rs:WP_001881685	methenyltetrahydrofolate cyclohydrolase [Vibrio cholerae].	50.86	291	133	3	1	291	26	306	3e-92	288
rs:WP_007713031	methylenetetrahydrofolate dehydrogenase [Cronobacter dublinensis].	53.47	288	124	3	1	288	1	278	3e-92	287
rs:XP_003758776	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Sarcophilus harrisii].	52.84	299	134	3	3	295	140	437	3e-92	293
rs:WP_023397166	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudoalteromonas luteoviolacea].	51.55	291	131	3	1	291	1	281	3e-92	287
rs:WP_037544633	hypothetical protein [Spirochaeta sp. JC230].	49.15	293	148	1	1	293	1	292	3e-92	287
rs:WP_006951843	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella micans].	45.58	294	159	1	1	294	1	293	3e-92	287
rs:WP_017939195	methenyltetrahydrofolate cyclohydrolase [Pseudomonas thermotolerans].	49.83	291	136	2	1	291	1	281	3e-92	287
rs:WP_025756118	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Enterobacter].	52.58	291	128	3	1	291	1	281	3e-92	287
tr:A0A091JGL8_9AVES	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFP19732.1}; Flags: Fragment;	51.86	295	135	3	3	291	3	296	3e-92	287
tr:H5SBN9_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.52	290	157	1	5	294	3	291	3e-92	287
rs:WP_047061269	methenyltetrahydrofolate cyclohydrolase [Enterobacter asburiae].	52.92	291	127	3	1	291	1	281	3e-92	287
tr:A0A067BIY0_9VIBR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.17	291	135	3	1	291	1	281	3e-92	287
rs:WP_004726573	methenyltetrahydrofolate cyclohydrolase [Vibrio furnissii].	50.52	291	134	3	1	291	1	281	3e-92	287
tr:E8MZT7_ANATU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.00	294	141	2	1	292	23	312	3e-92	288
rs:WP_010847199	methenyltetrahydrofolate cyclohydrolase [Xenorhabdus nematophila].	50.17	291	135	3	1	291	1	281	4e-92	287
rs:WP_006809817	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Enterobacter].	52.92	291	127	3	1	291	1	281	4e-92	287
rs:WP_041144398	methenyltetrahydrofolate cyclohydrolase [Raoultella ornithinolytica].	52.58	291	128	3	1	291	1	281	4e-92	287
rs:WP_000126776	methenyltetrahydrofolate cyclohydrolase [Vibrio sp. RC586].	50.17	291	135	3	1	291	1	281	4e-92	287
tr:H9GB21_ANOCA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSACAP00000006043}; Flags: Fragment;	51.85	297	136	3	3	293	37	332	4e-92	289
rs:WP_000126775	methenyltetrahydrofolate cyclohydrolase [Vibrio sp. RC341].	50.17	291	135	3	1	291	1	281	4e-92	287
rs:WP_038225364	methenyltetrahydrofolate cyclohydrolase [Vibrio sp. ER1A].	50.86	291	133	2	1	291	1	281	4e-92	287
rs:WP_042637963	methenyltetrahydrofolate cyclohydrolase [Aeromonas eucrenophila].	50.69	290	133	2	1	290	1	280	4e-92	287
rs:WP_005699820	methenyltetrahydrofolate cyclohydrolase [Haemophilus parainfluenzae].	50.35	288	132	2	1	288	1	277	4e-92	287
sp:FOLD_CAMJE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.72	290	128	5	5	293	3	281	4e-92	286
rs:WP_006117852	methenyltetrahydrofolate cyclohydrolase [Pantoea stewartii].	51.38	290	131	3	1	290	1	280	4e-92	287
rs:WP_024913950	methenyltetrahydrofolate cyclohydrolase [Serratia fonticola].	51.89	291	130	3	1	291	1	281	4e-92	287
rs:WP_023334768	MULTISPECIES: FolD protein [Enterobacter].	52.92	291	127	3	1	291	1	281	4e-92	287
rs:XP_009693997	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Cariama cristata].	51.17	299	139	3	3	295	3	300	4e-92	288
rs:WP_025563575	methenyltetrahydrofolate cyclohydrolase [Psychromonas sp. SP041].	51.89	291	130	3	1	291	1	281	4e-92	287
rs:WP_046550913	5,10-methylene-tetrahydrofolate cyclohydrolase [Sulfurovum lithotrophicum].	52.08	288	128	2	4	291	2	279	4e-92	286
tr:C3NP77_VIBCJ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.86	291	133	3	1	291	24	304	4e-92	288
rs:WP_025886751	methenyltetrahydrofolate cyclohydrolase [Shewanella haliotis].	50.86	291	133	3	1	291	1	281	4e-92	286
rs:WP_012991384	5,10-methylene-tetrahydrofolate dehydrogenase [Thermocrinis albus].	52.58	291	126	3	4	293	8	287	4e-92	287
rs:WP_010228642	5,10-methylene-tetrahydrofolate dehydrogenase [Gillisia marina].	50.00	284	142	0	5	288	3	286	4e-92	287
rs:WP_046356565	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas luteoviolacea].	52.23	291	129	3	1	291	1	281	4e-92	286
sp:FOLD_SHEHH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	291	135	2	1	291	1	281	4e-92	286
rs:WP_044532285	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Bacteroides intestinalis].	56.02	241	106	0	54	294	1	241	4e-92	285
rs:WP_021928300	methenyltetrahydrofolate cyclohydrolase [Alistipes sp. CAG:831].	48.59	284	145	1	5	288	3	285	4e-92	287
rs:WP_014205437	methenyltetrahydrofolate cyclohydrolase [Vibrio furnissii].	50.17	291	135	3	1	291	1	281	4e-92	286
rs:WP_045208481	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. 21].	50.00	290	135	2	1	290	1	280	4e-92	286
rs:WP_036863001	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella bivia].	46.94	294	155	1	1	294	1	293	4e-92	287
rs:WP_015465452	methenyltetrahydrofolate cyclohydrolase [Psychromonas sp. CNPT3].	50.17	291	135	3	1	291	1	281	4e-92	286
tr:A0A0C7N732_9THEO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	52.23	291	128	3	1	291	1	280	4e-92	286
rs:WP_015221624	5,10-methylene-tetrahydrofolate dehydrogenase [Cyanobacterium stanieri].	50.35	288	137	2	1	288	1	282	4e-92	287
rs:WP_020447360	5,10-methylene-tetrahydrofolate dehydrogenase [Salinarchaeum sp. Harcht-Bsk1].	52.61	287	134	2	3	289	2	286	4e-92	287
rs:WP_027335705	methenyltetrahydrofolate cyclohydrolase [Halomonas sp. HL-48].	50.52	291	134	2	1	291	1	281	4e-92	286
rs:XP_009571290	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Fulmarus glacialis].	50.84	299	140	3	3	295	3	300	4e-92	287
rs:WP_044199784	methenyltetrahydrofolate cyclohydrolase [Hyalangium minutum].	49.66	290	142	3	3	291	2	288	5e-92	287
rs:WP_043516976	methenyltetrahydrofolate cyclohydrolase [Halomonas sp. BC04].	50.69	290	133	2	1	290	1	280	5e-92	287
rs:WP_029685689	methenyltetrahydrofolate cyclohydrolase [Tatumella saanichensis].	51.20	291	132	2	1	291	1	281	5e-92	286
rs:WP_040210634	bifunctional protein FolD [Klebsiella pneumoniae].	52.92	291	127	3	1	291	1	281	5e-92	286
rs:XP_010014970	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Nestor notabilis].	51.17	299	139	3	3	295	3	300	5e-92	287
rs:WP_021909678	bifunctional protein FolD [Prevotella sp. CAG:755].	48.11	291	150	1	4	294	2	291	5e-92	287
rs:XP_010291931	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Phaethon lepturus].	51.17	299	139	3	3	295	3	300	5e-92	287
rs:WP_002031707	methylenetetrahydrofolate dehydrogenase [Vibrio cholerae].	50.52	291	134	3	1	291	1	281	5e-92	286
rs:WP_027290231	5,10-methylene-tetrahydrofolate cyclohydrolase [Rikenella microfusus].	50.17	291	139	2	4	294	2	286	5e-92	286
rs:WP_015415097	bifunctional protein FolD [Desulfovibrio piezophilus].	51.75	286	130	3	5	290	3	280	5e-92	286
sp:FOLD_AZOPC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.52	290	158	0	5	294	3	292	5e-92	286
rs:WP_046973899	methenyltetrahydrofolate cyclohydrolase [Photorhabdus temperata].	50.17	291	135	2	1	291	1	281	5e-92	286
rs:WP_022854024	5,10-methylene-tetrahydrofolate dehydrogenase [Thermodesulfatator atlanticus].	50.52	291	142	2	1	290	1	290	5e-92	287
rs:XP_010154489	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Eurypyga helias].	50.50	299	141	3	3	295	3	300	5e-92	287
rs:WP_035891784	methenyltetrahydrofolate cyclohydrolase [Kluyvera ascorbata].	52.58	291	128	3	1	291	1	281	5e-92	286
rs:WP_032411679	methenyltetrahydrofolate cyclohydrolase [Klebsiella pneumoniae].	52.58	291	128	3	1	291	1	281	6e-92	286
rs:WP_022945640	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas ruthenica].	50.17	291	135	2	1	291	1	281	6e-92	286
rs:WP_028114648	methenyltetrahydrofolate cyclohydrolase [Ferrimonas kyonanensis].	50.52	291	134	2	1	291	1	281	6e-92	286
rs:WP_036845777	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas cangingivalis].	46.90	290	154	0	2	291	7	296	6e-92	287
rs:XP_009863488	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Apaloderma vittatum].	51.17	299	139	3	3	295	7	304	6e-92	287
rs:WP_026744112	methenyltetrahydrofolate cyclohydrolase [Lonsdalea quercina].	50.86	291	133	2	1	291	1	281	6e-92	286
rs:WP_028527049	5,10-methylene-tetrahydrofolate cyclohydrolase [Runella limosa].	47.77	291	152	0	4	294	2	292	6e-92	286
rs:WP_038484389	methenyltetrahydrofolate cyclohydrolase [Halomonas campaniensis].	49.83	291	136	2	1	291	1	281	6e-92	286
rs:WP_037417187	methenyltetrahydrofolate cyclohydrolase [Shewanella xiamenensis].	50.17	291	135	2	1	291	1	281	6e-92	286
rs:WP_005819130	methenyltetrahydrofolate cyclohydrolase [Actinobacillus minor].	49.66	294	138	2	1	294	1	284	6e-92	286
rs:WP_017026011	methenyltetrahydrofolate cyclohydrolase [Vibrio rumoiensis].	50.52	291	134	2	1	291	1	281	6e-92	286
rs:WP_002685074	methenyltetrahydrofolate cyclohydrolase [Beggiatoa alba].	50.68	292	134	2	1	292	1	282	6e-92	286
rs:WP_021137677	bifunctional protein FolD [Campylobacter jejuni].	51.72	290	128	5	5	293	3	281	6e-92	286
rs:WP_036865094	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella melaninogenica].	46.60	294	156	1	1	294	1	293	6e-92	286
rs:WP_039486390	methenyltetrahydrofolate cyclohydrolase [Pectobacterium carotovorum].	50.86	291	133	3	1	291	1	281	6e-92	286
sp:FOLD_SHESH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	291	135	2	1	291	1	281	6e-92	286
rs:WP_028244313	methenyltetrahydrofolate cyclohydrolase [Pseudomonas caeni].	50.00	292	136	2	1	292	1	282	7e-92	286
rs:WP_016775590	5,10-methylene-tetrahydrofolate dehydrogenase [Anaerophaga thermohalophila].	49.48	287	145	0	4	290	2	288	7e-92	286
rs:WP_021703967	bifunctional protein FolD [Vibrio proteolyticus].	51.20	291	132	3	1	291	1	281	7e-92	286
rs:WP_016946532	bifunctional protein FolD [Klebsiella pneumoniae].	52.58	291	128	3	1	291	1	281	7e-92	286
rs:WP_044734238	methenyltetrahydrofolate cyclohydrolase [Shewanella algae].	51.20	291	132	3	1	291	1	281	7e-92	286
rs:WP_006785885	5,10-methylene-tetrahydrofolate dehydrogenase [Turicibacter sanguinis].	53.12	288	125	3	3	290	2	279	7e-92	286
rs:XP_003229576	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Anolis carolinensis].	51.85	297	136	3	3	293	55	350	7e-92	289
rs:XP_003206319	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Meleagris gallopavo].	51.17	299	139	3	3	295	9	306	7e-92	287
rs:WP_000126767	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Vibrio].	50.52	291	134	3	1	291	1	281	7e-92	286
rs:WP_017106149	methenyltetrahydrofolate cyclohydrolase [Vibrio tasmaniensis].	50.86	291	133	3	1	291	1	281	7e-92	286
sp:FOLD_KLEP3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.58	291	128	3	1	291	1	281	7e-92	286
rs:WP_014069199	methenyltetrahydrofolate cyclohydrolase [Enterobacter asburiae].	53.47	288	124	3	1	288	1	278	7e-92	286
rs:WP_004137856	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Klebsiella].	52.23	291	129	3	1	291	1	281	7e-92	286
rs:WP_039033886	methenyltetrahydrofolate cyclohydrolase [Shewanella sp. ECSMB14102].	50.86	291	133	3	1	291	1	281	7e-92	286
rs:WP_045897904	methenyltetrahydrofolate cyclohydrolase [Enterobacter cloacae].	52.92	291	127	3	1	291	1	281	7e-92	286
rs:WP_020885625	hypothetical protein [Desulfovibrio alkalitolerans].	51.40	286	132	2	5	290	3	281	7e-92	286
rs:WP_013454996	5,10-methylene-tetrahydrofolate dehydrogenase [Marivirga tractuosa].	47.24	290	153	0	5	294	4	293	7e-92	286
rs:WP_035611944	methenyltetrahydrofolate cyclohydrolase [Haloferula sp. BvORR071].	51.38	290	137	3	3	291	2	288	8e-92	286
sp:FOLD_NAUPA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.70	286	130	3	5	290	3	277	8e-92	286
rs:WP_024358987	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Klebsiella].	52.23	291	129	3	1	291	1	281	8e-92	286
rs:WP_041163185	methenyltetrahydrofolate cyclohydrolase, partial [Vibrio cholerae].	51.22	287	130	3	1	287	1	277	8e-92	286
rs:WP_015451801	methenyltetrahydrofolate cyclohydrolase [Azoarcus sp. KH32C].	50.85	293	133	3	1	293	1	282	8e-92	286
rs:XP_009878123	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Charadrius vociferus].	51.17	299	139	3	3	295	27	324	8e-92	288
rs:WP_031592132	methenyltetrahydrofolate cyclohydrolase [Pantoea agglomerans].	51.55	291	131	3	1	291	1	281	8e-92	286
rs:WP_000126778	methenyltetrahydrofolate cyclohydrolase [Vibrio cholerae].	50.52	291	134	3	1	291	1	281	8e-92	286
rs:WP_040229420	bifunctional protein FolD [Klebsiella pneumoniae].	52.58	291	128	3	1	291	1	281	8e-92	286
rs:WP_019902443	hypothetical protein [Chloroflexi bacterium SCGC AB-629-P13].	50.85	293	144	0	1	293	1	293	8e-92	286
rs:WP_020825565	methenyltetrahydrofolate cyclohydrolase [Serratia liquefaciens].	51.55	291	131	3	1	291	1	281	8e-92	286
rs:WP_010422909	5,10-methylene-tetrahydrofolate dehydrogenase [Anaerophaga thermohalophila].	49.13	289	147	0	4	292	2	290	8e-92	286
rs:WP_046897478	methenyltetrahydrofolate cyclohydrolase [Serratia marcescens].	51.20	291	132	3	1	291	1	281	8e-92	286
rs:WP_030381268	MULTISPECIES: hypothetical protein [Streptomyces].	49.83	295	139	2	1	295	1	286	8e-92	286
rs:WP_022149466	bifunctional protein FolD [Prevotella sp. CAG:1320].	47.77	291	151	1	4	294	2	291	8e-92	286
rs:XP_009283241	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Aptenodytes forsteri].	51.17	299	139	3	3	295	24	321	8e-92	287
rs:WP_045111098	methenyltetrahydrofolate cyclohydrolase [Moritella viscosa].	51.38	290	131	3	1	290	1	280	8e-92	286
tr:A4BHG8_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.86	291	133	2	1	291	17	297	8e-92	286
sp:FOLD_SHESA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	291	135	2	1	291	1	281	8e-92	286
rs:WP_023580443	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacterium limnosediminis].	50.00	290	145	0	4	293	2	291	9e-92	286
rs:XP_003793435	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Otolemur garnettii].	51.51	299	138	3	3	295	37	334	9e-92	288
rs:WP_042717786	methenyltetrahydrofolate cyclohydrolase [Klebsiella cf. planticola B43].	52.58	291	128	3	1	291	1	281	9e-92	286
rs:WP_023338131	FolD protein [Enterobacter sp. MGH 22].	52.58	291	128	3	1	291	1	281	9e-92	286
rs:WP_004940177	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Serratia].	51.20	291	132	3	1	291	1	281	9e-92	286
rs:XP_005145679	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Melopsittacus undulatus].	51.17	299	139	3	3	295	30	327	9e-92	288
rs:WP_024873390	methenyltetrahydrofolate cyclohydrolase [Tolumonas sp. BRL6-1].	51.55	291	131	2	1	291	1	281	9e-92	286
rs:WP_008938690	5,10-methylene-tetrahydrofolate dehydrogenase [Marinobacter santoriniensis].	51.21	289	131	2	1	289	1	279	9e-92	286
rs:XP_007910754	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Callorhinchus milii].	51.86	295	135	3	3	291	27	320	9e-92	287
rs:WP_017110310	methenyltetrahydrofolate cyclohydrolase [Vibrio tasmaniensis].	50.86	291	133	3	1	291	1	281	9e-92	286
rs:WP_022376861	bifunctional protein FolD [Clostridium sp. CAG:62].	54.55	286	116	3	3	288	2	273	9e-92	286
rs:WP_022111271	bifunctional protein FolD [Prevotella sp. CAG:604].	47.77	291	151	1	4	294	2	291	9e-92	286
rs:WP_028664619	5,10-methylene-tetrahydrofolate cyclohydrolase [Runella zeae].	46.39	291	156	0	4	294	2	292	9e-92	286
rs:WP_014882841	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Enterobacter].	52.58	291	128	3	1	291	1	281	9e-92	286
tr:A0A087VPY5_BALRE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFO14677.1}; Flags: Fragment;	51.86	295	135	3	3	291	3	296	9e-92	286
rs:WP_013671407	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella denticola].	47.28	294	154	1	1	294	1	293	1e-91	286
rs:WP_044630551	methenyltetrahydrofolate cyclohydrolase [Halomonas meridiana].	49.83	291	136	2	1	291	1	281	1e-91	286
rs:WP_044525668	bifunctional protein FolD [Francisella philomiragia].	49.31	288	134	3	5	291	3	279	1e-91	286
rs:WP_036788771	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas canoris].	46.53	288	154	0	4	291	12	299	1e-91	286
rs:WP_025078640	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella fusca].	46.94	294	155	1	1	294	1	293	1e-91	286
rs:WP_039316385	methenyltetrahydrofolate cyclohydrolase [Pectobacterium carotovorum].	50.52	291	134	3	1	291	1	281	1e-91	286
gp:CP002555_1568	Methylenetetrahydrofolate dehydrogenase (NADP+) [Vibrio cholerae LMA3984-4]	51.04	288	131	3	1	288	1	278	1e-91	286
rs:WP_024301809	methenyltetrahydrofolate cyclohydrolase [Pseudogulbenkiania sp. MAI-1].	51.56	289	130	3	1	289	1	279	1e-91	286
tr:H9L082_CHICK	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|Ensembl:ENSGALP00000022034};	51.17	299	139	3	3	295	32	329	1e-91	288
rs:WP_033637396	methenyltetrahydrofolate cyclohydrolase [Serratia marcescens].	51.20	291	132	3	1	291	1	281	1e-91	286
rs:WP_013095929	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Enterobacter].	52.58	291	128	3	1	291	1	281	1e-91	286
tr:C0AX22_9ENTR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.83	291	136	3	1	291	1	281	1e-91	286
rs:WP_007706347	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Cronobacter].	53.12	288	125	3	1	288	1	278	1e-91	286
rs:WP_036379755	5,10-methylene-tetrahydrofolate cyclohydrolase [Muricauda sp. MAR_2010_75].	47.22	288	152	0	4	291	2	289	1e-91	286
rs:XP_009322553	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Pygoscelis adeliae].	51.17	299	139	3	3	295	22	319	1e-91	287
rs:WP_020837044	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter jejuni].	51.72	290	128	5	5	293	3	281	1e-91	286
rs:XP_008822996	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Nannospalax galili].	50.85	295	138	3	3	291	37	330	1e-91	288
rs:WP_034259233	5,10-methylene-tetrahydrofolate cyclohydrolase [Altibacter lentus].	50.52	291	142	1	5	293	3	293	1e-91	286
sp:MTDC_CHICK	RecName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; Includes: RecName: Full=NAD-dependent methylenetetrahydrofolate dehydrogenase; EC=1.5.1.15; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Flags: Precursor;	51.17	299	139	3	3	295	32	329	1e-91	287
rs:WP_025865325	5,10-methylene-tetrahydrofolate cyclohydrolase [Prolixibacter bellariivorans].	48.28	290	148	1	5	294	3	290	1e-91	286
rs:WP_016493558	methylenetetrahydrofolate dehydrogenase [Pseudomonas resinovorans].	50.00	290	135	2	1	290	1	280	1e-91	286
tr:A0A091G8C0_9AVES	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFO70427.1}; Flags: Fragment;	51.19	295	137	3	3	291	3	296	1e-91	286
rs:WP_015405376	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfocapsa sulfexigens].	48.28	290	149	1	1	290	1	289	1e-91	286
rs:WP_023582607	5,10-methylene-tetrahydrofolate dehydrogenase [Proteus hauseri].	49.48	291	137	3	1	291	1	281	1e-91	286
rs:WP_010307420	methenyltetrahydrofolate cyclohydrolase [Pectobacterium carotovorum].	50.52	291	134	3	1	291	1	281	1e-91	286
tr:A0A087QJM2_APTFO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFM01426.1}; Flags: Fragment;	51.53	295	136	3	3	291	4	297	1e-91	286
sp:FOLD_CAMJR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.38	290	129	5	5	293	3	281	1e-91	285
tr:A0A093FC40_GAVST	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFV51826.1}; Flags: Fragment;	51.53	295	136	3	3	291	3	296	1e-91	286
rs:WP_039492302	methenyltetrahydrofolate cyclohydrolase [Pectobacterium carotovorum].	50.86	291	133	3	1	291	1	281	1e-91	286
rs:WP_039360514	methenyltetrahydrofolate cyclohydrolase [Pectobacterium carotovorum].	50.86	291	133	3	1	291	1	281	1e-91	286
rs:WP_039284658	methenyltetrahydrofolate cyclohydrolase [Pectobacterium carotovorum].	50.52	291	134	3	1	291	1	281	1e-91	286
rs:WP_023654297	tetrahydrofolate dehydrogenase [Erwinia piriflorinigrans].	51.03	292	133	3	1	292	1	282	1e-91	286
rs:WP_044874567	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. LFM046].	50.34	290	134	2	1	290	1	280	1e-91	285
rs:XP_010950742	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Camelus bactrianus].	51.53	295	136	3	3	291	41	334	1e-91	288
rs:XP_005234329	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Falco peregrinus].	51.17	299	139	3	3	295	22	319	1e-91	287
rs:WP_038806837	bifunctional protein FolD [Klebsiella pneumoniae].	52.23	291	129	3	1	291	1	281	1e-91	286
rs:WP_024548967	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Cronobacter].	52.58	291	128	3	1	291	1	281	1e-91	286
rs:WP_039545382	methenyltetrahydrofolate cyclohydrolase [Pectobacterium carotovorum].	50.52	291	134	3	1	291	1	281	1e-91	285
rs:WP_039608488	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas luteoviolacea].	51.89	291	130	3	1	291	1	281	1e-91	285
rs:WP_013465452	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Alteromonadales].	51.55	291	131	2	1	291	1	281	1e-91	285
rs:WP_027137073	5,10-methylene-tetrahydrofolate cyclohydrolase [Gaetbulibacter saemankumensis].	49.13	287	146	0	5	291	3	289	1e-91	286
rs:WP_036109930	methenyltetrahydrofolate cyclohydrolase [Mangrovibacter sp. MFB070].	52.58	291	128	3	1	291	1	281	1e-91	285
rs:WP_018200259	hypothetical protein [Hydrogenedentes bacterium JGI 0000077-D07].	46.21	290	155	1	4	293	8	296	1e-91	286
rs:XP_012644103	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Microcebus murinus].	51.86	295	135	3	3	291	37	330	1e-91	288
tr:G2ITJ7_9SPHN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	52.07	290	129	2	3	292	14	293	1e-91	286
rs:WP_042501001	methenyltetrahydrofolate cyclohydrolase [Vibrio maritimus].	50.52	291	134	2	1	291	1	281	1e-91	285
rs:WP_030005798	5,10-methylene-tetrahydrofolate dehydrogenase [Francisella noatunensis].	49.31	288	134	3	5	291	3	279	1e-91	285
rs:WP_021022246	methenyltetrahydrofolate cyclohydrolase [Salinivibrio costicola].	48.80	291	139	2	1	291	1	281	1e-91	285
rs:WP_036981898	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas sp. SCSIO_11900].	51.55	291	131	3	1	291	1	281	1e-91	285
rs:WP_038216735	methenyltetrahydrofolate cyclohydrolase [Xenorhabdus bovienii].	50.17	291	135	3	1	291	1	281	1e-91	286
sp:FOLD_SERP5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.72	290	130	3	1	290	1	280	1e-91	285
rs:WP_005608053	methenyltetrahydrofolate cyclohydrolase [Actinobacillus pleuropneumoniae].	50.69	288	131	2	1	288	1	277	1e-91	285
rs:XP_006176200	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Camelus ferus].	51.53	295	136	3	3	291	41	334	1e-91	288
rs:WP_013922208	5,10-methylene-tetrahydrofolate dehydrogenase [Francisella sp. TX077308].	49.31	288	134	3	5	291	3	279	1e-91	285
rs:WP_019440994	methenyltetrahydrofolate cyclohydrolase [Moritella marina].	51.03	290	132	3	1	290	1	280	1e-91	285
rs:WP_028376311	5,10-methylene-tetrahydrofolate cyclohydrolase [Leeuwenhoekiella sp. Hel_I_48].	48.59	284	146	0	5	288	3	286	1e-91	286
rs:WP_042285739	methenyltetrahydrofolate cyclohydrolase [Citrobacter sedlakii].	51.85	297	133	3	1	297	1	287	1e-91	285
rs:WP_038172954	methenyltetrahydrofolate cyclohydrolase [Vibrio pacinii].	51.55	291	131	3	1	291	1	281	1e-91	285
rs:WP_002871817	bifunctional protein FolD [Campylobacter jejuni].	51.38	290	129	5	5	293	3	281	1e-91	285
rs:WP_002676282	bifunctional protein FolD [Treponema denticola].	50.34	292	142	2	1	292	1	289	1e-91	286
tr:A0A091MMN9_CARIC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFP62820.1}; Flags: Fragment;	51.53	295	136	3	3	291	3	296	1e-91	286
rs:XP_010987236	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Camelus dromedarius].	51.53	295	136	3	3	291	41	334	1e-91	288
rs:WP_038258365	methenyltetrahydrofolate cyclohydrolase [Xenorhabdus bovienii].	49.83	291	136	3	1	291	1	281	2e-91	285
rs:WP_017104022	methenyltetrahydrofolate cyclohydrolase [Vibrio tasmaniensis].	51.20	291	132	3	1	291	1	281	2e-91	285
rs:WP_013409871	5,10-methylene-tetrahydrofolate dehydrogenase [Leadbetterella byssophila].	47.93	290	151	0	5	294	3	292	2e-91	285
rs:WP_013460418	5,10-methylene-tetrahydrofolate dehydrogenase [Sulfuricurvum kujiense].	50.52	287	132	2	4	290	2	278	2e-91	285
rs:WP_019934148	methenyltetrahydrofolate cyclohydrolase [Oceanimonas smirnovii].	49.83	291	136	2	1	291	1	281	2e-91	285
rs:WP_004099791	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Klebsiella].	52.23	291	129	3	1	291	1	281	2e-91	285
rs:WP_021964480	bifunctional protein FolD [Prevotella sp. CAG:1185].	47.08	291	153	1	4	294	2	291	2e-91	285
sp:FOLD_CYTH3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.30	286	145	0	4	289	2	287	2e-91	285
rs:WP_042552573	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fulva].	51.03	290	132	2	1	290	1	280	2e-91	285
rs:WP_026107623	methenyltetrahydrofolate cyclohydrolase [beta proteobacterium L13].	50.69	290	133	3	1	290	1	280	2e-91	285
rs:WP_008955297	methenyltetrahydrofolate cyclohydrolase [Pseudogulbenkiania ferrooxidans].	51.90	289	129	3	1	289	1	279	2e-91	285
rs:WP_039350913	5,10-methylene-tetrahydrofolate cyclohydrolase [Chryseobacterium jeonii].	48.63	292	149	1	3	294	2	292	2e-91	285
rs:WP_029840007	methenyltetrahydrofolate cyclohydrolase [Vibrio parahaemolyticus].	51.89	291	130	3	1	291	1	281	2e-91	285
rs:WP_040056771	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. REN51N].	50.85	293	132	3	1	293	1	281	2e-91	285
rs:WP_004130086	methenyltetrahydrofolate cyclohydrolase [Klebsiella oxytoca].	52.23	291	129	3	1	291	1	281	2e-91	285
rs:WP_038803695	methenyltetrahydrofolate cyclohydrolase [Pseudomonas nitroreducens].	50.00	290	135	2	1	290	1	280	2e-91	285
rs:WP_008358610	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus xiamenensis].	48.81	293	139	4	1	293	1	282	2e-91	285
rs:WP_007725707	5,10-methylene-tetrahydrofolate dehydrogenase [Brevibacillus sp. BC25].	50.17	293	135	4	1	293	1	282	2e-91	285
rs:XP_006760083	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Myotis davidii].	52.54	295	133	3	3	291	37	330	2e-91	287
rs:WP_002896140	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter jejuni].	51.38	290	129	5	5	293	3	281	2e-91	285
tr:A0A093F1Q4_TYTAL	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFV48176.1}; Flags: Fragment;	51.19	295	137	3	3	291	3	296	2e-91	285
rs:WP_004354821	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella denticola].	46.94	294	155	1	1	294	1	293	2e-91	285
rs:WP_037394426	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Serratia].	51.55	291	131	3	1	291	1	281	2e-91	285
rs:WP_041393079	methenyltetrahydrofolate cyclohydrolase [Sphingobium sp. SYK-6].	52.07	290	129	2	3	292	11	290	2e-91	286
sp:FOLD_MARHV	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.03	290	132	2	1	290	1	280	2e-91	285
rs:WP_028897782	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella sp. HUN102].	46.26	294	157	1	1	294	1	293	2e-91	285
rs:WP_039301034	methenyltetrahydrofolate cyclohydrolase [Cedecea neteri].	52.58	291	128	3	1	291	1	281	2e-91	285
rs:WP_016808736	methenyltetrahydrofolate cyclohydrolase [Klebsiella oxytoca].	51.89	291	130	3	1	291	1	281	2e-91	285
tr:A0A091MT03_9PASS	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFP80496.1}; Flags: Fragment;	51.19	295	137	3	3	291	3	296	2e-91	285
rs:WP_013607093	5,10-methylene-tetrahydrofolate dehydrogenase [Sphaerochaeta globosa].	50.70	286	139	1	4	289	2	285	2e-91	285
rs:WP_016928798	methenyltetrahydrofolate cyclohydrolase [Serratia marcescens].	51.20	291	132	3	1	291	1	281	2e-91	285
rs:XP_006031205	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Alligator sinensis].	51.17	299	139	3	3	295	39	336	2e-91	287
rs:WP_008865487	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacteria bacterium MS024-2A].	47.54	284	149	0	5	288	3	286	2e-91	285
rs:XP_009566214	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Cuculus canorus].	50.84	299	140	3	3	295	47	344	2e-91	287
rs:WP_008987665	methenyltetrahydrofolate cyclohydrolase [Photobacterium leiognathi].	53.26	291	126	2	1	291	1	281	2e-91	285
rs:WP_021897498	bifunctional protein FolD [Prevotella sp. CAG:924].	49.14	291	147	1	4	294	2	291	2e-91	285
rs:XP_010002237	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Chaetura pelagica].	50.84	299	140	3	3	295	18	315	2e-91	286
sp:FOLD_PECAS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.52	291	134	3	1	291	1	281	2e-91	285
rs:WP_007368507	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella multiformis].	46.26	294	157	1	1	294	1	293	2e-91	285
tr:B6WVJ1_9DELT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.41	284	131	1	5	288	73	349	2e-91	287
rs:WP_023009946	bifunctional protein FolD [Marinobacter sp. EVN1].	51.21	289	131	2	1	289	1	279	2e-91	285
rs:WP_027910718	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. URMO17WK12:I4].	50.69	290	133	2	1	290	1	280	2e-91	285
rs:WP_002892547	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter jejuni].	51.38	290	129	5	5	293	3	281	2e-91	285
sp:FOLD_PARUW	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	289	140	2	5	292	2	287	2e-91	285
rs:WP_038474912	methenyltetrahydrofolate cyclohydrolase [Cedecea neteri].	52.23	291	129	3	1	291	1	281	2e-91	285
rs:WP_039388351	methenyltetrahydrofolate cyclohydrolase [Pantoea agglomerans].	51.55	291	131	3	1	291	1	281	2e-91	285
rs:WP_022143426	bifunctional protein FolD [Ruminococcus sp. CAG:563].	50.87	287	130	4	4	290	3	278	2e-91	285
rs:WP_027063874	methenyltetrahydrofolate cyclohydrolase [Lonsdalea quercina].	50.86	291	133	2	1	291	1	281	2e-91	285
rs:WP_027021643	methenyltetrahydrofolate cyclohydrolase [Conchiformibius steedae].	48.62	290	139	2	1	290	1	280	2e-91	285
rs:WP_024790155	5,10-methylene-tetrahydrofolate cyclohydrolase [Lebetimonas sp. JH292].	50.70	286	130	3	5	290	3	277	2e-91	285
rs:WP_044206707	methenyltetrahydrofolate cyclohydrolase [Pectobacterium carotovorum].	50.86	291	133	3	1	291	1	281	2e-91	285
rs:WP_023297149	FolD protein [Klebsiella pneumoniae].	52.23	291	129	3	1	291	1	281	2e-91	285
rs:WP_027417567	5,10-methylene-tetrahydrofolate cyclohydrolase [Aneurinibacillus terranovensis].	50.17	291	134	3	1	291	1	280	2e-91	285
rs:WP_029729665	methenyltetrahydrofolate cyclohydrolase [Dickeya dianthicola].	51.55	291	131	3	1	291	1	281	2e-91	285
rs:WP_019391542	hypothetical protein [Bacillus endophyticus].	50.85	293	132	3	1	293	1	281	2e-91	285
rs:WP_005970043	methenyltetrahydrofolate cyclohydrolase [Pectobacterium wasabiae].	50.52	291	134	3	1	291	1	281	3e-91	285
rs:WP_039709134	methenyltetrahydrofolate cyclohydrolase [Actinobacillus pleuropneumoniae].	50.00	288	133	2	1	288	1	277	3e-91	285
rs:WP_002702952	5,10-methylene-tetrahydrofolate dehydrogenase [Treponema saccharophilum].	51.20	291	139	2	1	291	1	288	3e-91	285
rs:WP_023554554	5,10-methylene-tetrahydrofolate dehydrogenase [Brevibacillus panacihumi].	51.19	293	130	6	1	292	1	281	3e-91	285
rs:WP_022647304	MULTISPECIES: FolD protein [Enterobacteriaceae].	52.58	291	128	3	1	291	1	281	3e-91	285
rs:WP_022654944	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio sp. Dsv1].	51.77	282	129	1	5	286	3	277	3e-91	285
sp:FOLD_CAMJ8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.38	290	129	5	5	293	3	281	3e-91	285
rs:WP_044260893	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter jejuni].	51.38	290	129	5	5	293	3	281	3e-91	285
rs:WP_039134439	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavihumibacter sp. ZG627].	50.00	286	143	0	4	289	2	287	3e-91	285
rs:WP_032108509	methenyltetrahydrofolate cyclohydrolase [Haemophilus sp. FF7].	48.29	292	140	2	1	292	1	281	3e-91	285
rs:WP_044184880	methenyltetrahydrofolate cyclohydrolase [Enterobacter massiliensis].	51.20	291	132	3	1	291	1	281	3e-91	285
rs:WP_003355293	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus smithii].	51.54	293	131	4	1	293	1	282	3e-91	285
rs:WP_033756824	methenyltetrahydrofolate cyclohydrolase [Pantoea agglomerans].	51.55	291	131	3	1	291	1	281	3e-91	285
rs:WP_007162183	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	49.83	291	136	2	1	291	1	281	3e-91	285
rs:WP_013173195	5,10-methylene-tetrahydrofolate dehydrogenase [[Bacillus] selenitireducens].	50.34	290	133	3	1	290	1	279	3e-91	285
rs:WP_009181358	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio sp. FW1012B].	51.75	286	132	1	5	290	3	282	3e-91	285
rs:WP_010362227	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas citrea].	51.55	291	131	3	1	291	1	281	3e-91	285
rs:WP_035685545	methenyltetrahydrofolate cyclohydrolase [Avibacterium paragallinarum].	48.97	292	138	2	1	292	1	281	3e-91	285
rs:WP_039306386	methenyltetrahydrofolate cyclohydrolase [Pectobacterium betavasculorum].	50.86	291	133	3	1	291	1	281	3e-91	285
rs:WP_016710231	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas haloplanktis].	51.20	291	132	3	1	291	1	281	3e-91	285
rs:WP_004949430	methenyltetrahydrofolate cyclohydrolase [Serratia plymuthica].	51.20	291	132	3	1	291	1	281	3e-91	285
rs:WP_009623464	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. M1].	49.14	291	138	2	1	291	1	281	3e-91	285
rs:WP_036851427	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas macacae].	46.34	287	154	0	4	290	9	295	3e-91	285
rs:WP_044243157	methenyltetrahydrofolate cyclohydrolase [Klebsiella pneumoniae].	52.23	291	129	3	1	291	1	281	3e-91	285
rs:XP_005018464	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Anas platyrhynchos].	51.17	299	139	3	3	295	18	315	3e-91	286
rs:XP_006881058	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Elephantulus edwardii].	50.84	299	140	3	3	295	37	334	3e-91	287
tr:A0A093JEN9_EURHL	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFW09449.1}; Flags: Fragment;	50.85	295	138	3	3	291	3	296	3e-91	285
rs:WP_042320909	methenyltetrahydrofolate cyclohydrolase [Citrobacter farmeri].	51.85	297	133	3	1	297	1	287	3e-91	285
rs:WP_013006765	5,10-methylene-tetrahydrofolate dehydrogenase [Deferribacter desulfuricans].	48.45	291	139	2	3	293	2	281	3e-91	285
rs:WP_019454113	methenyltetrahydrofolate cyclohydrolase [Serratia marcescens].	51.20	291	132	3	1	291	1	281	3e-91	285
gp:CP000514_1816	methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+) [Marinobacter hydrocarbonoclasticus VT8]	51.03	290	132	2	1	290	19	298	3e-91	285
rs:WP_032587024	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter jejuni].	51.38	290	129	5	5	293	3	281	3e-91	284
rs:WP_009779221	5,10-methylene-tetrahydrofolate dehydrogenase [Leeuwenhoekiella blandensis].	48.94	284	145	0	5	288	3	286	3e-91	285
rs:WP_009303106	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio sp. 6_1_46AFAA].	51.42	282	130	1	5	286	3	277	3e-91	284
rs:WP_022489673	bifunctional protein FolD [Clostridium sp. CAG:567].	49.65	288	134	4	5	292	4	280	3e-91	284
rs:WP_042137780	methenyltetrahydrofolate cyclohydrolase [Pseudomonas oryzihabitans].	49.83	291	136	2	1	291	1	281	3e-91	284
sp:FOLD_SHESR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.83	291	136	2	1	291	1	281	3e-91	284
rs:WP_005369108	methenyltetrahydrofolate cyclohydrolase [Photobacterium angustum].	53.26	291	126	2	1	291	1	281	3e-91	284
rs:WP_005623248	methenyltetrahydrofolate cyclohydrolase [Actinobacillus ureae].	51.04	288	130	2	1	288	1	277	3e-91	284
rs:WP_018624296	methenyltetrahydrofolate cyclohydrolase [Kangiella aquimarina].	52.41	290	128	3	1	290	1	280	3e-91	284
rs:WP_026740023	methenyltetrahydrofolate cyclohydrolase [Lonsdalea quercina].	50.86	291	133	2	1	291	1	281	3e-91	285
rs:WP_022467577	bifunctional protein FolD [Acidaminococcus sp. CAG:917].	51.20	291	130	4	3	293	2	280	4e-91	284
rs:WP_007133325	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella salivae].	47.77	291	151	1	4	294	2	291	4e-91	285
sp:FOLD_CLOTH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.31	290	136	3	1	290	1	279	4e-91	284
tr:K1T5I2_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKC61530.1}; Flags: Fragment;	47.55	286	149	1	5	290	3	287	4e-91	284
rs:WP_005827289	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillales].	50.34	292	134	4	1	292	1	281	4e-91	284
rs:WP_034661254	bifunctional protein FolD [Bacillus pumilus].	48.12	293	141	3	1	293	1	282	4e-91	284
rs:WP_041979537	methenyltetrahydrofolate cyclohydrolase [Pseudomonas mendocina].	51.03	290	132	2	1	290	1	280	4e-91	284
rs:WP_010519261	5,10-methylene-tetrahydrofolate dehydrogenase [Mesoflavibacter zeaxanthinifaciens].	47.92	288	149	1	4	291	2	288	4e-91	285
rs:WP_045046122	methenyltetrahydrofolate cyclohydrolase [Rouxiella chamberiensis].	51.20	291	132	3	1	291	1	281	4e-91	284
tr:A0A0A0A6D3_CHAVO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGL88988.1}; Flags: Fragment;	51.53	295	136	3	3	291	3	296	4e-91	285
rs:WP_010662627	5,10-methylene-tetrahydrofolate dehydrogenase [Marinilabilia salmonicolor].	48.62	290	149	0	4	293	2	291	4e-91	285
rs:WP_006322343	methenyltetrahydrofolate cyclohydrolase [Serratia plymuthica].	51.20	291	132	3	1	291	1	281	4e-91	284
rs:WP_019386308	5,10-methylene-tetrahydrofolate dehydrogenase [Arenitalea lutea].	48.08	287	149	0	5	291	3	289	4e-91	285
rs:WP_043251232	methenyltetrahydrofolate cyclohydrolase [Pseudomonas knackmussii].	49.48	291	137	2	1	291	1	281	4e-91	284
tr:A0A073KQP5_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.17	291	135	2	1	291	53	333	4e-91	286
rs:WP_024559486	methenyltetrahydrofolate cyclohydrolase [Cronobacter pulveris].	52.78	288	126	3	1	288	1	278	4e-91	284
rs:WP_007576066	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella multisaccharivorax].	46.94	294	155	1	1	294	1	293	4e-91	285
rs:WP_023570196	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacterium cauense].	49.31	288	146	0	4	291	2	289	4e-91	285
sp:FOLD_CHLPD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.32	292	142	4	4	291	2	291	4e-91	285
rs:WP_017805372	methenyltetrahydrofolate cyclohydrolase [Avibacterium paragallinarum].	48.97	292	138	2	1	292	1	281	4e-91	284
rs:WP_007292158	methenyltetrahydrofolate cyclohydrolase [delta proteobacterium MLMS-1].	49.48	289	136	2	1	289	1	279	4e-91	284
rs:WP_002894941	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter jejuni].	51.38	290	129	5	5	293	3	281	4e-91	284
rs:WP_027939087	methenyltetrahydrofolate cyclohydrolase [Anaerobiospirillum succiniciproducens].	51.54	293	132	2	1	293	1	283	4e-91	284
rs:WP_046520621	methenyltetrahydrofolate cyclohydrolase [Rheinheimera sp. IITR-13].	50.86	291	133	3	1	291	1	281	4e-91	284
tr:H0VM10_CAVPO	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCPOP00000011427}; Flags: Fragment;	51.51	299	138	3	3	295	8	305	4e-91	285
rs:WP_043770998	methenyltetrahydrofolate cyclohydrolase [Desulfobulbus propionicus].	48.29	292	150	1	1	292	1	291	4e-91	285
rs:WP_039649570	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter insulaenigrae].	53.45	290	122	4	5	293	3	280	4e-91	284
rs:WP_022056508	bifunctional protein FolD [Clostridium sp. CAG:167].	52.45	286	122	3	3	288	2	273	4e-91	284
rs:WP_004360121	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella melaninogenica].	45.92	294	158	1	1	294	1	293	4e-91	284
rs:WP_002436289	methenyltetrahydrofolate cyclohydrolase [Escherichia hermannii].	51.20	291	132	3	1	291	1	281	5e-91	284
rs:XP_004398768	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Odobenus rosmarus divergens].	51.19	295	137	3	3	291	37	330	5e-91	286
rs:WP_038914378	methenyltetrahydrofolate cyclohydrolase [Dickeya zeae].	51.55	291	131	3	1	291	1	281	5e-91	284
rs:WP_022081402	bifunctional protein FolD [Ruminococcus sp. CAG:488].	50.17	287	132	3	4	290	3	278	5e-91	284
rs:WP_029827087	methenyltetrahydrofolate cyclohydrolase [Vibrio parahaemolyticus].	51.89	291	130	3	1	291	1	281	5e-91	284
rs:WP_017248009	5,10-methylene-tetrahydrofolate dehydrogenase [Brevibacillus brevis].	50.00	292	135	4	1	292	1	281	5e-91	284
rs:WP_026965864	5,10-methylene-tetrahydrofolate cyclohydrolase [Algoriphagus terrigena].	48.28	290	150	0	5	294	3	292	5e-91	284
rs:WP_002859530	bifunctional protein FolD [Campylobacter jejuni].	51.03	290	130	5	5	293	3	281	5e-91	284
rs:WP_044632754	5,10-methylene-tetrahydrofolate cyclohydrolase [Tamlana sedimentorum].	48.78	287	147	0	5	291	3	289	5e-91	284
tr:R0LNT2_ANAPL	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:EOB02113.1}; Flags: Fragment;	51.17	299	139	3	3	295	9	306	5e-91	285
rs:WP_040278676	5,10-methylene-tetrahydrofolate cyclohydrolase [Psychroserpens damuponensis].	49.48	289	146	0	5	293	3	291	5e-91	284
rs:WP_019844921	methenyltetrahydrofolate cyclohydrolase [Dickeya zeae].	51.55	291	131	3	1	291	1	281	5e-91	284
rs:WP_015712240	5,10-methylene-tetrahydrofolate dehydrogenase [Treponema azotonutricium].	51.21	289	138	2	3	291	2	287	5e-91	284
rs:WP_028579117	methenyltetrahydrofolate cyclohydrolase [Desulfobulbus japonicus].	47.26	292	153	1	1	292	1	291	5e-91	284
rs:WP_025674367	methenyltetrahydrofolate cyclohydrolase [Salinivibrio socompensis].	48.11	291	141	2	1	291	1	281	5e-91	284
tr:V1DBR5_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.17	291	135	2	1	291	53	333	5e-91	286
rs:WP_021445157	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. EGD-AK9].	50.69	290	133	2	1	290	1	280	5e-91	284
sp:FOLD_FRAP2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.96	288	135	3	5	291	3	279	5e-91	284
rs:WP_038268334	methenyltetrahydrofolate cyclohydrolase [Xenorhabdus cabanillasii].	50.17	291	135	3	1	291	1	281	5e-91	284
rs:WP_046406271	5,10-methylene-tetrahydrofolate cyclohydrolase [Clostridium sp. A254.MGS-251].	53.82	288	122	4	3	290	2	278	5e-91	284
rs:WP_015807887	5,10-methylene-tetrahydrofolate dehydrogenase [Pedobacter heparinus].	46.05	291	157	0	4	294	2	292	5e-91	284
gp:CP000492_967	5,10-methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [Chlorobium phaeobacteroides DSM 266]	48.80	291	145	3	4	291	15	304	5e-91	285
rs:WP_024788038	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Lebetimonas].	50.70	286	130	3	5	290	3	277	6e-91	284
sp:FOLD_IDILO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.04	288	131	2	1	288	1	278	6e-91	284
rs:WP_028892077	5,10-methylene-tetrahydrofolate cyclohydrolase [Tenacibaculum sp. 47A_GOM-205m].	50.17	287	143	0	5	291	3	289	6e-91	284
rs:WP_028830879	5,10-methylene-tetrahydrofolate cyclohydrolase [Proteobacteria bacterium JGI 0000113-E04].	47.55	286	150	0	5	290	3	288	6e-91	284
sp:FOLD_METFK	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.65	288	135	2	1	288	1	278	6e-91	284
rs:WP_039292925	bifunctional protein FolD [Pectobacterium atrosepticum].	50.17	291	135	3	1	291	1	281	6e-91	284
rs:WP_019967340	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella maculosa].	47.77	291	151	1	4	294	2	291	6e-91	284
rs:XP_002709778	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Oryctolagus cuniculus].	52.88	295	132	3	3	291	37	330	6e-91	286
rs:WP_009091578	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. Sc1].	51.20	291	132	3	1	291	1	281	6e-91	284
rs:XP_005430856	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Geospiza fortis].	51.03	292	136	3	10	295	23	313	6e-91	285
rs:WP_037417918	bifunctional protein FolD [Serratia grimesii].	51.38	290	131	3	1	290	1	280	6e-91	284
rs:WP_013968590	5,10-methylene-tetrahydrofolate dehydrogenase [Treponema caldarium].	50.17	293	143	2	1	293	1	290	6e-91	284
rs:WP_022234722	bifunctional protein FolD [Eubacterium sp. CAG:202].	52.96	287	125	3	4	290	2	278	6e-91	284
rs:WP_014201287	5,10-methylene-tetrahydrofolate dehydrogenase [Owenweeksia hongkongensis].	48.60	286	147	0	5	290	3	288	6e-91	284
sp:FOLD_SALEP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.78	288	126	3	1	288	1	278	6e-91	284
rs:WP_041703339	methenyltetrahydrofolate cyclohydrolase [Pseudogulbenkiania sp. NH8B].	51.56	289	130	3	1	289	1	279	6e-91	284
rs:WP_041149321	5,10-methylene-tetrahydrofolate cyclohydrolase [Sulfuricurvum sp. PC08-66].	49.65	288	135	2	4	291	2	279	6e-91	283
rs:WP_027711389	methenyltetrahydrofolate cyclohydrolase [Dickeya chrysanthemi].	50.85	293	134	3	1	293	1	283	6e-91	284
rs:WP_009230218	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella sp. oral taxon 317].	46.05	291	156	1	4	294	2	291	6e-91	284
rs:WP_021805409	methylenetetrahydrofolate dehydrogenase [Serratia fonticola].	50.86	291	133	3	1	291	1	281	6e-91	284
rs:WP_022545896	hypothetical protein [Bacteroidales bacterium CF].	48.25	286	145	2	5	289	3	286	6e-91	284
rs:XP_004634162	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Octodon degus].	51.51	299	138	3	3	295	37	334	7e-91	286
rs:WP_024106733	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Dickeya].	51.20	291	132	3	1	291	1	281	7e-91	284
rs:WP_001523379	methenyltetrahydrofolate cyclohydrolase [Salmonella enterica].	52.78	288	126	3	1	288	1	278	7e-91	284
rs:WP_021180058	methylenetetrahydrofolate dehydrogenase [Serratia fonticola].	50.86	291	133	3	1	291	1	281	7e-91	284
rs:WP_002927045	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter jejuni].	51.03	290	130	5	5	293	3	281	7e-91	283
rs:WP_025107124	methenyltetrahydrofolate cyclohydrolase [Klebsiella oxytoca].	51.89	291	130	3	1	291	1	281	7e-91	284
sp:FOLD_PECCP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	291	135	3	1	291	1	281	7e-91	284
rs:WP_022634345	bifunctional protein FolD [Dickeya solani].	51.55	291	131	3	1	291	1	281	7e-91	284
rs:WP_027905319	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. URMO17WK12:I3].	50.69	290	133	2	1	290	1	280	7e-91	283
tr:G2J0I8_PSEUL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.56	289	130	3	1	289	13	291	7e-91	284
rs:WP_034820064	methenyltetrahydrofolate cyclohydrolase [Idiomarina sp. 28-8].	50.69	288	132	2	1	288	1	278	7e-91	283
rs:WP_035558312	methenyltetrahydrofolate cyclohydrolase [Halomonas sp. KO116].	49.83	291	136	2	1	291	1	281	7e-91	284
rs:WP_009724467	methenyltetrahydrofolate cyclohydrolase [Halomonas sp. TD01].	49.83	291	136	2	1	291	1	281	7e-91	284
rs:WP_010671240	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pantoea].	51.20	291	132	3	1	291	1	281	7e-91	284
rs:WP_014991216	methenyltetrahydrofolate cyclohydrolase [Actinobacillus suis].	50.00	296	137	2	1	296	1	285	7e-91	283
rs:WP_012904909	methenyltetrahydrofolate cyclohydrolase [Citrobacter rodentium].	51.52	297	134	3	1	297	1	287	7e-91	284
rs:WP_014543676	methenyltetrahydrofolate cyclohydrolase [Erwinia sp. Ejp617].	50.34	292	135	3	1	292	1	282	7e-91	284
rs:WP_012668813	methenyltetrahydrofolate cyclohydrolase [Erwinia pyrifoliae].	50.68	292	134	3	1	292	1	282	7e-91	284
rs:WP_038924767	methenyltetrahydrofolate cyclohydrolase [Dickeya dadantii].	51.55	291	131	3	1	291	1	281	7e-91	284
rs:XP_003469034	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Cavia porcellus].	51.51	299	138	3	3	295	37	334	7e-91	286
tr:U3IG02_ANAPL	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAPLP00000006174};	51.17	299	139	3	3	295	38	335	7e-91	285
rs:WP_018651748	methenyltetrahydrofolate cyclohydrolase [Actinobacillus capsulatus].	50.00	288	133	2	1	288	1	277	7e-91	283
rs:WP_039273588	methenyltetrahydrofolate cyclohydrolase [Pectobacterium carotovorum].	50.52	291	134	3	1	291	1	281	8e-91	283
rs:WP_002710468	methenyltetrahydrofolate cyclohydrolase [Thiothrix nivea].	50.51	295	135	4	1	294	1	285	8e-91	283
rs:XP_008145652	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Eptesicus fuscus].	52.88	295	132	3	3	291	37	330	8e-91	286
rs:WP_022659055	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio desulfuricans].	49.83	287	137	1	5	291	3	282	8e-91	283
rs:WP_015480006	5,10-methylene-tetrahydrofolate dehydrogenase [Polaribacter sp. MED152].	49.13	287	146	0	5	291	3	289	8e-91	284
rs:WP_038424369	methenyltetrahydrofolate cyclohydrolase [Salmonella enterica].	52.78	288	126	3	1	288	1	278	8e-91	283
rs:WP_024991929	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella pleuritidis].	47.42	291	152	1	4	294	2	291	8e-91	284
rs:WP_038254436	methenyltetrahydrofolate cyclohydrolase [Yokenella regensburgei].	51.89	291	130	3	1	291	1	281	8e-91	283
tr:A0A093BPV3_CHAPE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFU94382.1}; Flags: Fragment;	51.19	295	137	3	3	291	3	296	8e-91	284
rs:WP_040266905	methenyltetrahydrofolate cyclohydrolase [Serratia symbiotica].	51.03	290	132	3	1	290	1	280	8e-91	283
rs:XP_005869491	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Myotis brandtii].	52.20	295	134	3	3	291	37	330	8e-91	286
rs:WP_023577158	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacterium saliperosum].	49.82	285	143	0	4	288	2	286	8e-91	284
rs:WP_018463363	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella paludivivens].	49.14	291	147	1	4	294	2	291	8e-91	284
rs:WP_038669398	methenyltetrahydrofolate cyclohydrolase [Cedecea neteri].	51.55	291	131	3	1	291	1	281	8e-91	283
rs:WP_046006717	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas rubra].	51.55	291	131	3	1	291	1	281	8e-91	283
rs:WP_028723943	methenyltetrahydrofolate cyclohydrolase [Pantoea ananatis].	50.52	291	134	3	1	291	1	281	8e-91	283
sp:FOLD_SALA4	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.78	288	126	3	1	288	1	278	8e-91	283
tr:S7MYN4_MYOBR	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:EPQ09694.1};	52.20	295	134	3	3	291	44	337	8e-91	286
rs:WP_045062578	methenyltetrahydrofolate cyclohydrolase [Photobacterium leiognathi].	53.26	291	126	2	1	291	1	281	8e-91	283
rs:WP_034903943	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter sp. MIT 97-5078].	52.41	290	125	4	5	293	3	280	8e-91	283
rs:XP_008943551	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Merops nubicus].	50.50	299	141	3	3	295	3	300	8e-91	284
rs:WP_005612228	methenyltetrahydrofolate cyclohydrolase [Actinobacillus pleuropneumoniae].	50.00	288	133	2	1	288	1	277	9e-91	283
rs:WP_042242463	5,10-methylene-tetrahydrofolate cyclohydrolase [Jejuia pallidilutea].	49.48	287	145	0	5	291	3	289	9e-91	283
rs:WP_038424172	methenyltetrahydrofolate cyclohydrolase [Klebsiella oxytoca].	52.23	291	129	3	1	291	1	281	9e-91	283
rs:WP_044259781	5,10-methylene-tetrahydrofolate cyclohydrolase [Candidatus Prevotella conceptionensis].	46.05	291	156	1	4	294	2	291	9e-91	283
rs:WP_025070799	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella oulorum].	47.08	291	153	1	4	294	2	291	9e-91	283
rs:XP_004882737	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Heterocephalus glaber].	51.51	299	138	3	3	295	37	334	9e-91	285
rs:WP_039358646	bifunctional protein FolD [Candidatus Protochlamydia amoebophila].	49.83	289	141	2	5	292	2	287	9e-91	283
rs:XP_005438204	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Falco cherrug].	51.17	299	139	3	3	295	74	371	9e-91	286
rs:WP_008566643	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella maculosa].	47.77	291	151	1	4	294	2	291	9e-91	283
rs:WP_008455989	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Enterobacteriaceae].	52.23	291	129	3	1	291	1	281	9e-91	283
rs:WP_024159552	methenyltetrahydrofolate cyclohydrolase [Salmonella enterica].	52.78	288	126	3	1	288	1	278	9e-91	283
rs:XP_006219064	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Vicugna pacos].	50.85	295	138	3	3	291	41	334	9e-91	286
rs:WP_012885608	methenyltetrahydrofolate cyclohydrolase [Dickeya dadantii].	51.55	291	131	3	1	291	1	281	9e-91	283
rs:WP_000729158	methenyltetrahydrofolate cyclohydrolase [Escherichia albertii].	52.60	289	127	3	1	289	1	279	9e-91	283
rs:WP_036128464	methenyltetrahydrofolate cyclohydrolase [Marinobacter sp. AK21].	51.56	289	130	2	1	289	1	279	9e-91	283
rs:WP_047183860	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacilli bacterium VT-13-104].	52.07	290	128	4	1	290	1	279	9e-91	283
rs:WP_040000287	methenyltetrahydrofolate cyclohydrolase [Dickeya chrysanthemi].	51.20	291	132	3	1	291	1	281	9e-91	283
rs:WP_012768991	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Dickeya].	51.20	291	132	3	1	291	1	281	1e-90	283
rs:WP_014593113	methenyltetrahydrofolate cyclohydrolase [Pantoea ananatis].	50.52	291	134	3	1	291	1	281	1e-90	283
rs:WP_021853320	bifunctional protein FolD [Prevotella sp. CAG:255].	46.74	291	154	1	4	294	2	291	1e-90	283
rs:WP_000729167	bifunctional protein FolD [Salmonella enterica].	52.78	288	126	3	1	288	1	278	1e-90	283
rs:WP_008812683	methenyltetrahydrofolate cyclohydrolase [Enterobacteriaceae bacterium 9_2_54FAA].	50.52	291	134	3	1	291	1	281	1e-90	283
sp:FOLD_THISH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.40	286	129	2	1	286	1	276	1e-90	283
rs:WP_003831112	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Citrobacter].	52.78	288	126	3	1	288	1	278	1e-90	283
rs:WP_028109515	methenyltetrahydrofolate cyclohydrolase [Ferrimonas futtsuensis].	50.52	291	134	2	1	291	1	281	1e-90	283
rs:WP_028584405	methenyltetrahydrofolate cyclohydrolase [Desulfobulbus mediterraneus].	48.97	292	148	1	1	292	1	291	1e-90	283
rs:WP_043267154	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. AAC].	48.80	291	139	2	1	291	1	281	1e-90	283
rs:WP_004286429	bifunctional protein FolD [Francisella philomiragia].	48.61	288	136	3	5	291	3	279	1e-90	283
rs:WP_013318869	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Dickeya].	51.55	291	131	3	1	291	1	281	1e-90	283
rs:WP_041852424	methenyltetrahydrofolate cyclohydrolase [Enterobacter sp. Bisph2].	51.20	291	132	3	1	291	1	281	1e-90	283
rs:WP_014699039	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pectobacterium].	50.17	291	135	3	1	291	1	281	1e-90	283
rs:WP_010280312	methenyltetrahydrofolate cyclohydrolase [Pectobacterium carotovorum].	50.17	291	135	3	1	291	1	281	1e-90	283
rs:WP_028627766	methenyltetrahydrofolate cyclohydrolase [Pseudomonas resinovorans].	50.34	290	134	2	1	290	1	280	1e-90	283
rs:WP_044305996	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter jejuni].	51.03	290	130	5	5	293	3	281	1e-90	283
rs:WP_002860513	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter jejuni].	51.03	290	130	5	5	293	3	281	1e-90	283
tr:T1DGQ4_9DIPT	SubName: Full=Putative nad-dependent methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:JAA93281.1}; Flags: Fragment;	50.17	295	140	3	3	291	5	298	1e-90	284
rs:WP_008682445	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio sp. 3_1_syn3].	51.06	282	131	1	5	286	3	277	1e-90	283
rs:WP_028452348	methenyltetrahydrofolate cyclohydrolase [Chitinilyticum aquatile].	51.89	291	130	3	1	291	1	281	1e-90	283
rs:WP_045269140	methenyltetrahydrofolate cyclohydrolase [Enterobacter sp. 35730].	52.23	291	129	3	1	291	1	281	1e-90	283
rs:WP_025121632	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Serratia].	50.17	291	135	3	1	291	1	281	1e-90	283
rs:WP_020879677	hypothetical protein [Desulfovibrio sp. X2].	49.83	289	138	2	5	293	3	284	1e-90	283
rs:WP_036934683	methenyltetrahydrofolate cyclohydrolase [Proteus vulgaris].	49.14	291	138	3	1	291	1	281	1e-90	283
rs:WP_045152051	methenyltetrahydrofolate cyclohydrolase [Photobacterium angustum].	52.92	291	127	2	1	291	1	281	1e-90	283
rs:WP_007501171	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus].	48.46	293	140	4	1	293	1	282	1e-90	283
rs:WP_045261866	methenyltetrahydrofolate cyclohydrolase [Enterobacter sp. 35014].	52.23	291	129	3	1	291	1	281	1e-90	283
rs:WP_044902999	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium P6B14].	54.23	284	116	5	3	286	2	271	1e-90	283
rs:WP_038921072	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Dickeya].	51.20	291	132	3	1	291	1	281	1e-90	283
rs:XP_314619	AGAP004677-PB [Anopheles gambiae str. PEST].	48.64	294	144	3	3	290	2	294	1e-90	284
rs:WP_010581819	5,10-methylene-tetrahydrofolate dehydrogenase [Schlesneria paludicola].	49.66	290	139	1	1	290	1	283	1e-90	283
sp:FOLD_NATTJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.49	293	136	3	1	293	1	281	1e-90	283
rs:WP_008958006	methenyltetrahydrofolate cyclohydrolase [Halomonas sp. HAL1].	49.83	291	136	2	1	291	1	281	1e-90	283
rs:WP_042391742	methenyltetrahydrofolate cyclohydrolase [Escherichia vulneris].	51.89	291	130	3	1	291	1	281	1e-90	283
sp:FOLD_PSEHT	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.55	291	131	3	1	291	1	281	1e-90	283
rs:WP_018941336	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio sp. AKL11].	52.08	288	128	2	1	288	1	278	1e-90	283
rs:WP_029946724	methenyltetrahydrofolate cyclohydrolase [Vibrio parahaemolyticus].	51.75	286	128	2	6	291	1	276	1e-90	283
rs:WP_009111981	methenyltetrahydrofolate cyclohydrolase [Brenneria sp. EniD312].	50.17	291	135	3	1	291	1	281	1e-90	283
rs:WP_006788359	methenyltetrahydrofolate cyclohydrolase [Thiorhodospira sibirica].	47.93	290	141	2	1	290	1	280	1e-90	283
rs:WP_009012058	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella].	45.92	294	158	1	1	294	1	293	1e-90	283
rs:WP_000729152	methenyltetrahydrofolate cyclohydrolase [Salmonella enterica].	52.78	288	126	3	1	288	1	278	1e-90	283
rs:WP_010862101	5,10-methylene-tetrahydrofolate dehydrogenase [Plesiomonas shigelloides].	50.52	291	134	2	1	291	1	281	1e-90	283
tr:A0A0C1JKB8_9CHLA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.83	289	141	2	5	292	21	306	1e-90	284
rs:WP_005823341	methenyltetrahydrofolate cyclohydrolase [Actinobacillus minor].	48.64	294	141	2	1	294	1	284	1e-90	283
rs:WP_015965477	5,10-methylene-tetrahydrofolate dehydrogenase [Enterobacteriaceae bacterium strain FGI 57].	51.89	291	130	3	1	291	1	281	1e-90	283
rs:WP_024307999	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. P818].	50.69	290	133	2	1	290	1	280	1e-90	283
rs:WP_010259049	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. SL1_M5].	51.20	291	132	3	1	291	1	281	1e-90	283
rs:WP_007351817	methenyltetrahydrofolate cyclohydrolase [Marinobacter sp. ELB17].	51.72	290	130	2	1	290	1	280	1e-90	283
rs:WP_027313650	methenyltetrahydrofolate cyclohydrolase [Balneatrix alpica].	49.48	289	136	2	1	289	1	279	1e-90	283
tr:G9Z4S8_9ENTR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.89	291	130	3	1	291	9	289	1e-90	283
rs:WP_014108056	methenyltetrahydrofolate cyclohydrolase [Glaciecola nitratireducens].	51.20	291	132	3	1	291	1	281	1e-90	283
rs:WP_046477124	methenyltetrahydrofolate cyclohydrolase [Citrobacter amalonaticus].	51.52	297	134	3	1	297	1	287	1e-90	283
rs:WP_044334070	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus safensis].	48.12	293	141	3	1	293	1	282	1e-90	283
rs:WP_013632522	5,10-methylene-tetrahydrofolate dehydrogenase [Pedobacter saltans].	45.02	291	160	0	4	294	2	292	1e-90	283
rs:XP_012513659	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Propithecus coquereli].	51.53	295	136	3	3	291	37	330	1e-90	285
rs:WP_008350517	5,10-methylene-tetrahydrofolate dehydrogenase [Thiovulum sp. ES].	50.00	286	129	3	5	290	3	274	1e-90	283
sp:FOLD_BACP2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.46	293	140	4	1	293	1	282	1e-90	283
rs:WP_005158281	methenyltetrahydrofolate cyclohydrolase [Yersinia enterocolitica].	51.20	291	132	3	1	291	1	281	1e-90	283
rs:XP_002124013	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Ciona intestinalis].	52.86	297	133	3	3	293	42	337	1e-90	285
rs:WP_045148290	methenyltetrahydrofolate cyclohydrolase [Photobacterium angustum].	52.92	291	127	2	1	291	1	281	1e-90	283
tr:A8SPI3_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.94	283	125	4	4	286	10	281	1e-90	283
rs:WP_046339031	methenyltetrahydrofolate cyclohydrolase [Pasteurella multocida].	48.61	288	137	2	1	288	1	277	1e-90	283
rs:WP_032265112	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	52.43	288	127	3	1	288	1	278	2e-90	283
rs:WP_000729162	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	52.43	288	127	3	1	288	1	278	2e-90	283
rs:WP_028669971	methenyltetrahydrofolate cyclohydrolase [Saccharospirillum impatiens].	49.83	291	136	2	1	291	1	281	2e-90	283
rs:WP_014661379	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter cetorum].	46.88	288	143	2	5	292	8	285	2e-90	283
sp:FOLD_ENT38	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.89	291	130	3	1	291	1	281	2e-90	283
rs:WP_038080850	methenyltetrahydrofolate cyclohydrolase [Treponema socranskii].	49.83	291	143	2	1	291	1	288	2e-90	283
rs:WP_008585439	5,10-methylene-tetrahydrofolate dehydrogenase [Niabella soli].	48.96	288	144	3	4	289	2	288	2e-90	283
tr:E8RDX2_DESPD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.29	292	150	1	1	292	22	312	2e-90	284
rs:XP_001846734	bifunctional protein folD [Culex quinquefasciatus].	50.17	295	140	3	3	291	2	295	2e-90	283
rs:WP_046515895	5,10-methylene-tetrahydrofolate cyclohydrolase [Cryomorphaceae bacterium ASP10-05a].	50.88	285	140	0	6	290	5	289	2e-90	283
rs:WP_029895344	methenyltetrahydrofolate cyclohydrolase [Desulfovibrio sp. L21-Syr-AB].	47.75	289	144	1	5	293	3	284	2e-90	283
tr:A7BU12_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.66	292	137	2	1	292	1	282	2e-90	283
rs:WP_017676717	methenyltetrahydrofolate cyclohydrolase [Pseudomonas alcaliphila].	51.03	290	132	2	1	290	1	280	2e-90	283
rs:WP_026898420	5,10-methylene-tetrahydrofolate cyclohydrolase [Pedobacter oryzae].	45.02	291	160	0	4	294	2	292	2e-90	283
tr:G5L5S0_SALET	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	52.78	288	126	3	1	288	1	278	2e-90	283
rs:WP_038627492	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. PSNIH2].	51.55	291	131	3	1	291	1	281	2e-90	283
rs:WP_033576222	methenyltetrahydrofolate cyclohydrolase [Dickeya chrysanthemi].	51.20	291	132	3	1	291	1	281	2e-90	283
rs:WP_020477073	methenyltetrahydrofolate cyclohydrolase [Dickeya zeae].	51.20	291	132	3	1	291	1	281	2e-90	283
rs:WP_009838719	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas tunicata].	50.86	291	133	2	1	291	1	281	2e-90	283
rs:WP_006324012	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Serratia].	51.20	291	132	3	1	291	1	281	2e-90	283
rs:WP_024422943	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus].	48.46	293	140	4	1	293	1	282	2e-90	282
rs:WP_042281336	methenyltetrahydrofolate cyclohydrolase [Candidatus Protochlamydia sp. R18].	49.83	289	141	2	5	292	2	287	2e-90	283
rs:WP_047068853	5,10-methylene-tetrahydrofolate cyclohydrolase [Brevibacillus formosus].	49.66	292	136	4	1	292	1	281	2e-90	282
sp:FOLD_SHEFN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	291	135	3	1	291	1	281	2e-90	282
rs:WP_016520555	hypothetical protein [Treponema socranskii].	49.83	291	143	2	1	291	1	288	2e-90	283
rs:WP_022059044	MULTISPECIES: bifunctional protein FolD [Coprococcus].	51.94	283	125	4	4	286	3	274	2e-90	282
rs:WP_013488314	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cellulosilyticus].	49.15	293	138	4	1	293	1	282	2e-90	282
rs:WP_027306055	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter cuniculorum].	50.00	290	132	4	5	293	3	280	2e-90	282
sp:FOLD_COXB2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.59	290	142	2	1	290	1	280	2e-90	282
rs:WP_009110387	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio sp. U5L].	51.05	286	134	1	5	290	3	282	2e-90	283
rs:WP_043037947	methenyltetrahydrofolate cyclohydrolase [Vibrio parahaemolyticus].	51.35	296	129	4	1	291	1	286	2e-90	283
rs:WP_027708974	methenyltetrahydrofolate cyclohydrolase [Zooshikella ganghwensis].	49.48	291	137	2	1	291	1	281	2e-90	282
rs:WP_035056252	methenyltetrahydrofolate cyclohydrolase [Andreprevotia chitinilytica].	50.52	291	134	3	1	291	1	281	2e-90	282
rs:WP_026487558	5,10-methylene-tetrahydrofolate cyclohydrolase [Caldanaerobius polysaccharolyticus].	49.66	290	135	2	4	293	2	280	2e-90	282
rs:WP_005706163	methenyltetrahydrofolate cyclohydrolase [Haemophilus parahaemolyticus].	50.17	293	136	2	1	293	1	283	2e-90	282
tr:U1FN63_TRESO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.83	291	143	2	1	291	13	300	2e-90	283
rs:WP_038839433	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter coli].	51.72	290	128	5	5	293	3	281	2e-90	282
rs:WP_025092987	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus pumilus].	48.46	293	140	4	1	293	1	282	2e-90	282
sp:FOLD_WOLSU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.52	287	132	2	4	290	2	278	2e-90	282
rs:WP_021939106	bifunctional protein FolD [Coprococcus sp. CAG:782].	53.87	284	120	3	3	286	2	274	2e-90	282
rs:WP_016507009	5,10-methylene-tetrahydrofolate cyclohydrolase [Salmonella enterica].	52.78	288	126	3	1	288	1	278	2e-90	282
sp:FOLD_SHESW	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.48	291	137	2	1	291	1	281	2e-90	282
rs:WP_023640335	methenyltetrahydrofolate cyclohydrolase [Dickeya zeae].	51.20	291	132	3	1	291	1	281	2e-90	282
tr:T1E8H6_ANOAQ	SubName: Full=Putative c1-tetrahydrofolate synthase {ECO:0000313|EMBL:JAA99418.1};	50.51	293	138	3	3	289	2	293	2e-90	283
sp:FOLD_SHEB9	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	291	135	2	1	291	1	281	2e-90	282
sp:FOLD_DESMR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	293	140	1	5	297	3	289	2e-90	283
rs:WP_017492640	methenyltetrahydrofolate cyclohydrolase [gamma proteobacterium WG36].	50.86	291	133	3	1	291	1	281	2e-90	282
rs:WP_047371511	methenyltetrahydrofolate cyclohydrolase [Kluyvera intermedia].	51.20	291	132	3	1	291	1	281	2e-90	282
rs:WP_024823216	methenyltetrahydrofolate cyclohydrolase [Desulfovibrio magneticus].	51.40	286	133	1	5	290	3	282	2e-90	283
rs:WP_037458430	methenyltetrahydrofolate cyclohydrolase [Shewanella sp. HN-41].	49.48	291	137	2	1	291	1	281	2e-90	282
rs:WP_004390633	methenyltetrahydrofolate cyclohydrolase [Yersinia kristensenii].	51.55	291	131	3	1	291	1	281	2e-90	282
rs:WP_000729151	methenyltetrahydrofolate cyclohydrolase [Shigella flexneri].	52.25	289	128	3	1	289	1	279	2e-90	282
gp:CP006730_587	methylenetetrahydrofolate dehydrogenase (NADP+) [Dehalococcoides mccartyi GY50]	48.63	292	149	1	1	292	1	291	2e-90	283
rs:WP_008342219	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus].	48.46	293	140	4	1	293	1	282	2e-90	282
rs:WP_014020864	5,10-methylene-tetrahydrofolate dehydrogenase [Cyclobacterium marinum].	49.13	289	147	0	6	294	10	298	2e-90	283
rs:WP_020893874	methylenetetrahydrofolate dehydrogenase [Cyclobacterium qasimii].	49.13	289	147	0	6	294	10	298	2e-90	283
sp:FOLD_ALKEH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.03	290	132	3	1	290	1	280	3e-90	282
rs:WP_013791342	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fulva].	50.34	290	134	2	1	290	1	280	3e-90	282
rs:WP_006009987	methylenetetrahydrofolate dehydrogenase [Glaciecola pallidula].	51.55	291	131	3	1	291	1	281	3e-90	282
rs:WP_043315049	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. PI1].	48.80	291	139	2	1	291	1	281	3e-90	282
rs:WP_036930134	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella timonensis].	47.40	289	151	1	6	294	4	291	3e-90	282
rs:XP_006096849	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Myotis lucifugus].	51.86	295	135	3	3	291	37	330	3e-90	284
rs:XP_006151296	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Tupaia chinensis].	52.54	295	133	3	3	291	37	330	3e-90	284
rs:WP_033850810	MULTISPECIES: bifunctional protein FolD [Yersinia].	51.20	291	132	3	1	291	1	281	3e-90	282
rs:WP_017357655	methenyltetrahydrofolate cyclohydrolase [Actinobacillus pleuropneumoniae].	50.35	288	132	2	1	288	1	277	3e-90	282
rs:WP_001393855	bifunctional protein FolD [Escherichia coli].	51.52	297	134	3	1	297	1	287	3e-90	282
rs:WP_028456064	methenyltetrahydrofolate cyclohydrolase [Chitinilyticum litopenaei].	51.55	291	131	3	1	291	1	281	3e-90	282
rs:WP_037000804	methenyltetrahydrofolate cyclohydrolase [Pseudomonas pseudoalcaligenes].	50.69	290	133	2	1	290	1	280	3e-90	282
sp:FOLD_CAMJD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.03	290	130	5	5	293	3	281	3e-90	282
rs:WP_036189503	methenyltetrahydrofolate cyclohydrolase [Marinobacterium sp. AK27].	53.68	285	122	3	6	290	9	283	3e-90	282
sp:FOLD_SHEWM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.45	291	140	2	1	291	1	281	3e-90	282
rs:WP_033731804	methenyltetrahydrofolate cyclohydrolase [Pantoea vagans].	50.86	291	133	3	1	291	1	281	3e-90	282
rs:WP_002958348	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas].	51.55	291	131	3	1	291	1	281	3e-90	282
rs:WP_002934585	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter jejuni].	51.03	290	130	5	5	293	3	281	3e-90	282
rs:WP_023238706	bifunctional protein FolD [Salmonella enterica].	52.43	288	127	3	1	288	1	278	3e-90	282
sp:FOLD_ECO24	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.52	297	134	3	1	297	1	287	3e-90	282
rs:WP_013739107	5,10-methylene-tetrahydrofolate dehydrogenase [Sphaerochaeta coccoides].	49.65	288	143	1	4	291	2	287	3e-90	282
sp:FOLD_ACIF2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.93	290	141	2	1	290	1	280	3e-90	282
rs:WP_036314372	methenyltetrahydrofolate cyclohydrolase [Methylophaga thiooxydans].	48.97	290	138	2	1	290	1	280	3e-90	282
sp:FOLD_PSEA7	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.00	290	135	2	1	290	1	280	3e-90	282
tr:A0A091LQR5_9GRUI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFP45106.1}; Flags: Fragment;	50.52	291	141	2	3	291	3	292	3e-90	282
rs:WP_041613420	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. JDR-2].	49.66	292	136	3	1	292	1	281	3e-90	282
rs:WP_013513468	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio aespoeensis].	51.40	286	131	3	5	290	3	280	3e-90	282
rs:WP_013947887	5,10-methylene-tetrahydrofolate dehydrogenase [Hyphomicrobium sp. MC1].	50.85	293	134	2	1	293	1	283	3e-90	282
rs:WP_031388113	methenyltetrahydrofolate cyclohydrolase [Desulfonatronum thiodismutans].	48.24	284	140	2	5	288	2	278	3e-90	282
tr:W8UB07_YEREN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.86	291	133	3	1	291	1	281	3e-90	282
rs:WP_008127813	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas].	51.55	291	131	3	1	291	1	281	3e-90	282
rs:WP_029653904	methenyltetrahydrofolate cyclohydrolase [Marinobacter daepoensis].	50.87	289	132	3	1	289	1	279	3e-90	282
rs:WP_036811634	methenyltetrahydrofolate cyclohydrolase [Photorhabdus luminescens].	49.83	291	136	2	1	291	1	281	3e-90	282
rs:WP_034169283	bifunctional protein FolD [Escherichia coli].	51.52	297	134	3	1	297	1	287	3e-90	282
rs:WP_033810555	bifunctional protein FolD [Escherichia coli].	51.52	297	134	3	1	297	1	287	3e-90	282
rs:WP_029701633	bifunctional protein FolD [Escherichia coli].	51.52	297	134	3	1	297	1	287	3e-90	282
rs:WP_024238856	bifunctional protein FolD [Escherichia coli].	51.52	297	134	3	1	297	1	287	3e-90	282
sp:FOLD_ECO7I	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.25	289	128	3	1	289	1	279	3e-90	282
sp:FOLD_SHEB2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	291	135	2	1	291	1	281	3e-90	282
rs:WP_020456848	methenyltetrahydrofolate cyclohydrolase [Enterobacter sp. R4-368].	52.23	291	129	3	1	291	1	281	3e-90	282
tr:C6CU27_PAESJ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.66	292	136	3	1	292	2	282	3e-90	282
rs:WP_046217848	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus endophyticus].	50.51	293	133	3	1	293	1	281	3e-90	282
rs:WP_000729166	bifunctional protein FolD [Salmonella enterica].	52.43	288	127	3	1	288	1	278	3e-90	282
rs:WP_001506987	bifunctional protein FolD [Escherichia coli].	51.52	297	134	3	1	297	1	287	3e-90	282
rs:WP_038287982	5,10-methylene-tetrahydrofolate cyclohydrolase [[Clostridium] straminisolvens].	49.66	290	135	3	1	290	1	279	3e-90	282
rs:WP_039179869	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus].	48.46	293	140	4	1	293	1	282	3e-90	282
gp:ECOFOLD_1	5,10-methylene-tetrahydrofolate dehydrogenase/5, 10-methenyl-dtetrahydrofolate cyclo-hydrolase [Escherichia coli str. K-12 substr. W3110]	51.52	297	134	3	1	297	1	287	3e-90	282
sp:FOLD_SALTI	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.78	288	126	3	1	288	1	278	3e-90	282
sp:FOLD_SHEAM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	291	135	2	1	291	1	281	3e-90	282
rs:WP_009638471	methenyltetrahydrofolate cyclohydrolase [Serratia sp. M24T3].	50.86	291	133	3	1	291	1	281	3e-90	282
rs:WP_003849457	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pantoea].	50.86	291	133	3	1	291	1	281	3e-90	282
tr:K9IJ01_DESRO	SubName: Full=Putative c1-tetrahydrofolate synthase {ECO:0000313|EMBL:JAA46728.1};	51.86	295	135	3	3	291	37	330	3e-90	284
rs:WP_045084035	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Photobacterium].	52.58	291	128	2	1	291	1	281	3e-90	282
rs:WP_026584290	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. J33].	50.00	292	135	4	1	292	1	281	3e-90	282
rs:WP_000729159	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	52.25	289	128	3	1	289	1	279	4e-90	282
sp:FOLD_ECO8A	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.52	297	134	3	1	297	1	287	4e-90	282
rs:XP_009918616	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Haliaeetus albicilla].	51.71	292	134	3	3	288	8	298	4e-90	283
rs:WP_039187210	methenyltetrahydrofolate cyclohydrolase [Hafnia paralvei].	50.17	291	135	3	1	291	1	281	4e-90	282
rs:WP_004847085	methenyltetrahydrofolate cyclohydrolase [Hafnia alvei].	50.17	291	135	3	1	291	1	281	4e-90	282
sp:FOLD1_PSEMY	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.69	290	133	2	1	290	1	280	4e-90	281
rs:WP_014871723	methenyltetrahydrofolate cyclohydrolase [Marinobacter sp. BSs20148].	51.72	290	130	2	1	290	1	280	4e-90	282
rs:WP_019250448	methenyltetrahydrofolate cyclohydrolase, partial [Yersinia pestis].	51.20	291	132	3	1	291	1	281	4e-90	281
rs:WP_021978247	bifunctional protein FolD [Clostridium sp. CAG:793].	50.35	288	129	4	3	290	2	275	4e-90	281
rs:WP_042676647	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. B40].	50.17	291	135	3	1	291	1	281	4e-90	282
rs:WP_038163120	methenyltetrahydrofolate cyclohydrolase [Trabulsiella guamensis].	51.89	291	130	3	1	291	1	281	4e-90	282
sp:FOLD_ECO27	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.43	288	127	3	1	288	1	278	4e-90	282
tr:K2CK70_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.95	292	141	2	1	292	1	281	4e-90	282
rs:WP_038844962	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter coli].	51.72	290	128	5	5	293	3	281	4e-90	282
rs:WP_032251159	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	51.52	297	134	3	1	297	1	287	4e-90	282
rs:NP_001002181	bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Danio rerio].	50.67	298	140	3	3	294	30	326	4e-90	283
rs:WP_044837644	methenyltetrahydrofolate cyclohydrolase [Thalassomonas viridans].	48.80	291	139	2	1	291	1	281	4e-90	281
rs:XP_010561159	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Haliaeetus leucocephalus].	51.71	292	134	3	3	288	32	322	4e-90	283
sp:FOLD_BACLD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.49	293	137	3	1	293	1	282	4e-90	281
sp:FOLD_CHLPB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.65	284	141	1	5	286	3	286	4e-90	282
rs:WP_004704975	methenyltetrahydrofolate cyclohydrolase [Yersinia aldovae].	51.20	291	132	3	1	291	1	281	4e-90	282
rs:WP_000729171	bifunctional protein FolD [Escherichia fergusonii].	52.25	289	128	3	1	289	1	279	4e-90	282
sp:FOLD_CITK8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.43	288	127	3	1	288	1	278	4e-90	282
rs:WP_010386467	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas rubra].	51.20	291	132	3	1	291	1	281	4e-90	281
rs:WP_021560763	FolD protein [Escherichia coli].	52.43	288	127	3	1	288	1	278	4e-90	282
rs:WP_042093372	bifunctional protein FolD [Escherichia coli].	52.43	288	127	3	1	288	1	278	4e-90	282
rs:WP_024237464	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	51.52	297	134	3	1	297	1	287	4e-90	282
rs:WP_005615198	methenyltetrahydrofolate cyclohydrolase [Actinobacillus pleuropneumoniae].	50.00	288	133	2	1	288	1	277	4e-90	281
rs:WP_024791497	5,10-methylene-tetrahydrofolate cyclohydrolase [Lebetimonas sp. JS032].	50.35	286	130	3	5	290	3	276	4e-90	281
rs:WP_020452135	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus].	49.83	293	136	3	1	293	1	282	4e-90	281
rs:WP_018002402	methenyltetrahydrofolate cyclohydrolase [zeta proteobacterium SCGC AB-604-O16].	47.80	295	142	3	1	293	1	285	4e-90	282
rs:WP_038394166	methenyltetrahydrofolate cyclohydrolase [Salmonella enterica].	52.78	288	126	3	1	288	1	278	4e-90	281
rs:WP_038814633	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter jejuni].	51.03	290	130	5	5	293	3	281	4e-90	281
rs:WP_038631653	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Yersinia].	51.20	291	132	3	1	291	1	281	4e-90	282
rs:WP_000729173	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Escherichia].	52.43	288	127	3	1	288	1	278	4e-90	281
rs:WP_012828323	methenyltetrahydrofolate cyclohydrolase [Haliangium ochraceum].	50.17	291	135	2	1	291	1	281	4e-90	281
rs:WP_046051424	methenyltetrahydrofolate cyclohydrolase [Yersinia enterocolitica].	51.55	291	131	3	1	291	1	281	4e-90	282
rs:WP_009745656	5,10-methylene-tetrahydrofolate dehydrogenase [Capnocytophaga sp. oral taxon 338].	48.43	287	146	1	5	291	3	287	4e-90	282
rs:WP_035343442	methenyltetrahydrofolate cyclohydrolase [Dickeya sp. DW 0440].	51.20	291	132	3	1	291	1	281	4e-90	281
rs:WP_038835990	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter coli].	51.72	290	128	5	5	293	3	281	4e-90	281
tr:C9Q0P0_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.70	291	157	1	4	294	3	292	4e-90	282
gp:CP006573_529	methenyltetrahydrofolate cyclohydrolase [Mannheimia haemolytica D171]	52.01	273	121	2	21	293	3	265	4e-90	281
tr:W1X0K2_ECOLX	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:ETJ23721.1}; Flags: Fragment;	52.43	288	127	3	1	288	19	296	4e-90	282
rs:WP_015671268	5,10-methylene-tetrahydrofolate dehydrogenase [Serratia marcescens].	50.17	291	135	3	1	291	1	281	4e-90	281
rs:WP_001637565	bifunctional protein FolD [Escherichia coli].	51.52	297	134	3	1	297	1	287	4e-90	281
rs:WP_025790075	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella].	45.70	291	157	1	4	294	2	291	4e-90	282
rs:WP_033868456	bifunctional protein FolD [Escherichia coli].	51.90	289	129	3	1	289	1	279	5e-90	281
rs:WP_000729168	bifunctional protein FolD [Salmonella enterica].	52.43	288	127	3	1	288	1	278	5e-90	281
tr:W5U914_ICTPU	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:AHH38064.1};	51.36	294	136	3	3	290	30	322	5e-90	283
rs:WP_009708365	5,10-methylene-tetrahydrofolate dehydrogenase [Desmospora sp. 8437].	49.31	288	136	2	3	290	4	281	5e-90	281
rs:WP_027226822	methenyltetrahydrofolate cyclohydrolase [Legionella pneumophila].	48.80	291	139	2	1	291	1	281	5e-90	281
rs:WP_045957477	methenyltetrahydrofolate cyclohydrolase [Xenorhabdus poinarii].	49.48	291	137	3	1	291	1	281	5e-90	281
rs:WP_046081736	methenyltetrahydrofolate cyclohydrolase [Escherichia fergusonii].	52.25	289	128	3	1	289	1	279	5e-90	281
rs:WP_009144005	methenyltetrahydrofolate cyclohydrolase [Succinatimonas hippei].	51.04	288	131	2	1	288	1	278	5e-90	281
rs:WP_023182863	5,10-methylene-tetrahydrofolate dehydrogenase [Salmonella enterica].	52.43	288	127	3	1	288	1	278	5e-90	281
rs:WP_002861493	bifunctional protein FolD [Campylobacter jejuni].	50.34	290	132	5	5	293	3	281	5e-90	281
sp:FOLD_YERP3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.20	291	132	3	1	291	1	281	5e-90	281
rs:WP_033567905	methenyltetrahydrofolate cyclohydrolase [Dickeya sp. 2B12].	50.86	291	133	3	1	291	1	281	5e-90	281
sp:FOLD_ESCF3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.52	297	134	3	1	297	1	287	5e-90	281
rs:WP_017221209	methenyltetrahydrofolate cyclohydrolase [Moritella dasanensis].	50.00	290	135	3	1	290	1	280	5e-90	281
rs:WP_004581870	5,10-methylene-tetrahydrofolate dehydrogenase [Marinobacter nanhaiticus].	50.17	291	135	3	1	291	1	281	5e-90	281
rs:WP_000729172	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Escherichia].	52.43	288	127	3	1	288	1	278	5e-90	281
rs:WP_013024950	methenyltetrahydrofolate cyclohydrolase [Pantoea ananatis].	50.17	291	135	3	1	291	1	281	5e-90	281
rs:WP_046009183	methenyltetrahydrofolate cyclohydrolase [Oleispira antarctica].	50.52	291	134	3	1	291	1	281	5e-90	281
rs:WP_017872396	hypothetical protein [Candidatus Caldatribacterium saccharofermentans].	50.35	288	135	2	4	291	5	284	5e-90	281
rs:WP_005182439	methenyltetrahydrofolate cyclohydrolase [Yersinia intermedia].	51.20	291	132	3	1	291	1	281	5e-90	281
rs:WP_032186924	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	51.52	297	134	3	1	297	1	287	5e-90	281
rs:WP_018617055	hypothetical protein [Segetibacter koreensis].	48.94	282	144	0	5	286	3	284	6e-90	281
sp:FOLD_PHOLL	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.48	291	137	2	1	291	1	281	6e-90	281
rs:WP_008292331	methenyltetrahydrofolate cyclohydrolase [Methylophaga thiooxydans].	48.97	290	138	2	1	290	1	280	6e-90	281
tr:A0A0A0FZ84_ECOLX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	52.43	288	127	3	1	288	33	310	6e-90	283
rs:WP_027832430	methenyltetrahydrofolate cyclohydrolase [Marinobacter sp. HL-58].	49.83	291	136	2	1	291	1	281	6e-90	281
rs:WP_028913327	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella sp. MA2016].	49.48	291	146	1	4	294	2	291	6e-90	281
rs:WP_027855173	methenyltetrahydrofolate cyclohydrolase [Marinobacterium litorale].	51.56	289	130	3	2	290	3	281	6e-90	281
rs:WP_012982016	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio sp. K90mix].	52.08	288	128	2	1	288	1	278	6e-90	281
rs:WP_007291785	5,10-methylene-tetrahydrofolate dehydrogenase [delta proteobacterium MLMS-1].	46.92	292	154	1	1	292	1	291	6e-90	281
tr:A0A034TGE7_9VIBR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.37	292	131	4	1	291	1	282	6e-90	281
sp:FOLD_HALOH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.69	290	129	4	3	290	2	279	6e-90	281
tr:A0A0A0H1B8_ECOLX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	52.43	288	127	3	1	288	33	310	6e-90	282
rs:WP_016739914	5,10-methylene-tetrahydrofolate dehydrogenase [Brevibacillus brevis].	50.00	292	135	4	1	292	1	281	6e-90	281
rs:WP_032223939	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	52.25	289	128	3	1	289	1	279	6e-90	281
rs:WP_013701704	5,10-methylene-tetrahydrofolate dehydrogenase [Treponema succinifaciens].	48.97	290	145	2	1	290	1	287	6e-90	281
rs:WP_039383072	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. PSNIH1].	50.69	290	133	3	1	290	1	280	6e-90	281
rs:WP_034164266	methenyltetrahydrofolate cyclohydrolase [Edwardsiella tarda].	50.69	290	133	3	1	290	1	280	6e-90	281
rs:WP_012683359	5,10-methylene-tetrahydrofolate dehydrogenase [Gemmatimonas aurantiaca].	50.00	294	145	2	1	293	1	293	6e-90	281
rs:WP_001545434	bifunctional protein FolD [Escherichia coli].	51.90	289	129	3	1	289	1	279	6e-90	281
rs:WP_036771927	methenyltetrahydrofolate cyclohydrolase [Photorhabdus asymbiotica].	49.14	291	138	2	1	291	1	281	6e-90	281
rs:WP_028006988	methenyltetrahydrofolate cyclohydrolase [Solimonas flava].	51.74	288	129	3	1	288	1	278	6e-90	281
rs:WP_013264555	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella melaninogenica].	45.58	294	159	1	1	294	1	293	6e-90	281
rs:WP_032248416	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	52.43	288	127	3	1	288	1	278	6e-90	281
rs:WP_028768222	methenyltetrahydrofolate cyclohydrolase [Shewanella fidelis].	49.83	291	136	3	1	291	1	281	6e-90	281
rs:WP_027221493	methenyltetrahydrofolate cyclohydrolase [Legionella pneumophila].	48.80	291	139	2	1	291	1	281	7e-90	281
tr:F7RME8_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.48	291	137	2	1	291	53	333	7e-90	283
rs:WP_018983022	methenyltetrahydrofolate cyclohydrolase [Salinimonas chungwhensis].	51.20	291	132	2	1	291	1	281	7e-90	281
rs:WP_029551797	5,10-methylene-tetrahydrofolate cyclohydrolase [Thermocrinis sp. GBS].	51.70	294	128	4	2	293	4	285	7e-90	281
rs:WP_008170527	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas sp. BSi20652].	51.55	291	131	3	1	291	1	281	7e-90	281
rs:WP_021990416	bifunctional protein FolD [Prevotella sp. CAG:1092].	47.74	287	149	1	4	290	2	287	7e-90	281
rs:XP_001649874	AAEL014871-PA [Aedes aegypti].	51.19	295	136	4	3	290	33	326	7e-90	283
sp:FOLD_DEHM1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.63	292	149	1	1	292	1	291	7e-90	281
rs:WP_032342519	bifunctional protein FolD [Escherichia coli].	51.18	297	135	3	1	297	1	287	7e-90	281
rs:WP_000729157	methenyltetrahydrofolate cyclohydrolase [Escherichia albertii].	52.43	288	127	3	1	288	1	278	7e-90	281
sp:FOLD_MANSM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.32	292	138	2	1	292	1	282	7e-90	281
rs:WP_004315502	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter jejuni].	51.03	290	130	5	5	293	3	281	7e-90	281
rs:XP_010226224	PREDICTED: LOW QUALITY PROTEIN: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Tinamus guttatus].	50.34	298	142	3	3	295	62	358	7e-90	284
rs:WP_017455716	methenyltetrahydrofolate cyclohydrolase [Kosakonia sacchari].	52.23	291	129	3	1	291	1	281	7e-90	281
rs:WP_015259924	methylenetetrahydrofolate dehydrogenase [Thioalkalivibrio nitratireducens].	51.39	288	130	2	1	288	1	278	7e-90	281
rs:WP_004712716	methenyltetrahydrofolate cyclohydrolase [Yersinia frederiksenii].	51.20	291	132	3	1	291	1	281	7e-90	281
rs:WP_022941602	methenyltetrahydrofolate cyclohydrolase [Psychromonas hadalis].	50.52	291	134	3	1	291	1	281	7e-90	281
tr:A0A087FBV0_9PSED	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.69	290	133	2	1	290	1	280	7e-90	281
rs:WP_027669695	methenyltetrahydrofolate cyclohydrolase [Rheinheimera baltica].	51.38	290	131	3	1	290	1	280	7e-90	281
rs:WP_022264200	bifunctional protein FolD [Clostridium sp. CAG:352].	53.82	288	122	4	3	290	2	278	7e-90	281
rs:WP_022282955	tetrahydrofolate dehydrogenase [Clostridium sp. CAG:448].	52.26	287	127	2	6	292	5	281	7e-90	281
tr:A0A0A7LDK4_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.66	290	145	1	3	292	2	290	7e-90	281
rs:WP_017925872	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio].	52.08	288	128	2	1	288	1	278	8e-90	281
rs:WP_045846097	methenyltetrahydrofolate cyclohydrolase [Aquitalea magnusonii].	51.05	286	130	3	1	286	1	276	8e-90	281
sp:FOLD_COXB1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.59	290	142	2	1	290	1	280	8e-90	281
rs:WP_039346184	methenyltetrahydrofolate cyclohydrolase [Pectobacterium carotovorum].	49.83	291	136	3	1	291	1	281	8e-90	281
rs:WP_042963895	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter coli].	51.72	290	128	5	5	293	3	281	8e-90	281
rs:WP_021488920	methenyltetrahydrofolate cyclohydrolase [Pseudomonas mendocina].	50.69	290	133	2	1	290	1	280	8e-90	281
rs:WP_004873348	methenyltetrahydrofolate cyclohydrolase [Yersinia mollaretii].	51.20	291	132	3	1	291	1	281	8e-90	281
rs:WP_006637499	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus sonorensis].	50.51	293	134	4	1	293	1	282	8e-90	281
rs:WP_003215670	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus pumilus].	47.78	293	142	3	1	293	1	282	8e-90	281
rs:WP_040725568	methenyltetrahydrofolate cyclohydrolase [Thiomicrospira sp. Kp2].	48.79	289	138	2	1	289	1	279	8e-90	281
rs:WP_040217823	methenyltetrahydrofolate cyclohydrolase [Haemophilus parahaemolyticus].	49.83	293	137	2	1	293	1	283	8e-90	281
rs:XP_005329412	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Ictidomys tridecemlineatus].	50.84	299	140	3	3	295	37	334	8e-90	283
rs:XP_010125252	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Chlamydotis macqueenii].	49.51	305	141	3	3	295	3	306	8e-90	282
rs:WP_032286039	bifunctional protein FolD [Escherichia coli].	51.18	297	135	3	1	297	1	287	8e-90	281
rs:WP_004090848	bifunctional protein FolD [Escherichia coli].	51.18	297	135	3	1	297	1	287	8e-90	281
rs:WP_025765580	methenyltetrahydrofolate cyclohydrolase [Shigella flexneri].	52.43	288	127	3	1	288	1	278	8e-90	281
rs:WP_045440822	methenyltetrahydrofolate cyclohydrolase [Citrobacter sp. S-77].	52.43	288	127	3	1	288	1	278	8e-90	281
rs:WP_043001513	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Citrobacter].	51.18	297	135	3	1	297	1	287	8e-90	281
rs:WP_021508629	methenyltetrahydrofolate cyclohydrolase [Pantoea dispersa].	50.86	291	133	3	1	291	1	281	8e-90	281
rs:WP_037476142	methenyltetrahydrofolate cyclohydrolase [Snodgrassella alvi].	50.69	290	133	3	1	290	1	280	8e-90	281
rs:WP_046131879	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. TH008].	49.49	293	137	4	1	293	1	282	8e-90	281
rs:WP_012823535	methenyltetrahydrofolate cyclohydrolase [Halothiobacillus neapolitanus].	48.81	293	140	2	1	293	1	283	8e-90	281
rs:WP_044638397	5,10-methylene-tetrahydrofolate cyclohydrolase [Siansivirga zeaxanthinifaciens].	48.43	287	148	0	5	291	3	289	9e-90	281
sp:FOLD_ACTP2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.35	288	132	2	1	288	1	277	9e-90	281
rs:WP_008126137	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella timonensis].	47.40	289	151	1	6	294	4	291	9e-90	281
rs:XP_006789747	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Neolamprologus brichardi].	52.04	294	134	4	3	290	30	322	9e-90	283
rs:WP_012881917	5,10-methylene-tetrahydrofolate dehydrogenase [Dehalococcoides mccartyi].	48.63	292	149	1	1	292	1	291	9e-90	281
rs:WP_036842559	methenyltetrahydrofolate cyclohydrolase [Photorhabdus temperata].	49.48	291	137	2	1	291	1	281	9e-90	281
rs:WP_032091831	methenyltetrahydrofolate cyclohydrolase [Necropsobacter rosorum].	48.29	292	140	2	1	292	1	281	9e-90	281
rs:WP_045735969	methenyltetrahydrofolate cyclohydrolase [Pseudomonas pseudoalcaligenes].	50.69	290	133	2	1	290	1	280	9e-90	281
rs:WP_021583356	tetrahydrofolate dehydrogenase [Prevotella pleuritidis].	47.08	291	153	1	4	294	2	291	9e-90	281
rs:WP_013681726	5,10-methylene-tetrahydrofolate dehydrogenase [Hippea maritima].	50.00	286	131	3	5	290	3	276	9e-90	280
rs:WP_032221124	bifunctional protein FolD [Escherichia coli].	52.08	288	128	3	1	288	1	278	9e-90	281
rs:WP_004714650	methenyltetrahydrofolate cyclohydrolase [Yersinia rohdei].	51.20	291	132	3	1	291	1	281	9e-90	281
rs:WP_020570566	hypothetical protein [Lewinella persica].	46.37	289	155	0	4	292	2	290	9e-90	281
rs:WP_028973151	hypothetical protein [Spirochaeta cellobiosiphila].	51.38	290	140	1	1	290	1	289	9e-90	281
rs:XP_005385581	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Chinchilla lanigera].	51.86	295	135	3	3	291	37	330	1e-89	283
rs:WP_027093763	5,10-methylene-tetrahydrofolate cyclohydrolase [Cohnella thermotolerans].	52.05	292	129	4	1	292	1	281	1e-89	281
rs:WP_035471679	methenyltetrahydrofolate cyclohydrolase [Gammaproteobacteria bacterium MFB021].	48.62	290	139	2	1	290	1	280	1e-89	281
rs:WP_022260243	bifunctional protein FolD [Eubacterium sp. CAG:251].	53.47	288	123	4	3	290	2	278	1e-89	281
rs:WP_020843554	methylenetetrahydrofolate dehydrogenase [Salmonella bongori].	52.43	288	127	3	1	288	1	278	1e-89	281
rs:WP_000729170	methenyltetrahydrofolate cyclohydrolase [Salmonella enterica].	52.43	288	127	3	1	288	1	278	1e-89	281
rs:WP_013715273	methenyltetrahydrofolate cyclohydrolase [Pseudomonas mendocina].	50.34	290	134	2	1	290	1	280	1e-89	280
rs:WP_028867617	methenyltetrahydrofolate cyclohydrolase [Psychromonas arctica].	49.48	291	137	3	1	291	1	281	1e-89	280
rs:WP_026850704	methenyltetrahydrofolate cyclohydrolase [Gemmatimonas sp. AP64].	50.00	294	145	2	1	293	1	293	1e-89	281
rs:WP_042964888	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter coli].	52.07	290	127	5	5	293	3	281	1e-89	280
rs:WP_025398915	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter coli].	51.72	290	128	5	5	293	3	281	1e-89	280
rs:WP_013357051	methenyltetrahydrofolate cyclohydrolase [Pantoea vagans].	50.52	291	134	3	1	291	1	281	1e-89	281
rs:WP_021579058	FolD protein [Escherichia coli].	52.08	288	128	3	1	288	1	278	1e-89	281
rs:WP_024523762	methenyltetrahydrofolate cyclohydrolase [Edwardsiella hoshinae].	50.69	290	133	3	1	290	1	280	1e-89	280
rs:WP_018625788	5,10-methylene-tetrahydrofolate dehydrogenase [Niabella aurantiaca].	47.74	287	149	1	4	289	2	288	1e-89	281
rs:WP_010559668	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas spongiae].	50.69	290	133	3	1	290	1	280	1e-89	280
sp:FOLD_ACTP7	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.00	288	133	2	1	288	1	277	1e-89	280
rs:WP_039142489	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavihumibacter solisilvae].	48.43	287	148	0	4	290	2	288	1e-89	281
tr:A0A091DI40_FUKDA	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:KFO30163.1};	51.17	299	139	3	3	295	37	334	1e-89	283
rs:WP_022238041	bifunctional protein FolD [Clostridium sp. CAG:343].	48.28	290	139	3	3	292	2	280	1e-89	280
rs:WP_040095082	5,10-methylene-tetrahydrofolate cyclohydrolase [Geoalkalibacter ferrihydriticus].	50.34	290	131	4	3	291	2	279	1e-89	280
rs:WP_034614885	methenyltetrahydrofolate cyclohydrolase [Chelonobacter oris].	50.17	293	135	3	1	293	1	282	1e-89	280
sp:FOLD_COXBN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.24	290	143	2	1	290	1	280	1e-89	280
rs:WP_044169287	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas catoniae].	45.30	287	157	0	5	291	8	294	1e-89	281
rs:WP_031376076	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. 3.5.1].	50.52	291	134	3	1	291	1	281	1e-89	280
rs:XP_011573589	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Aquila chrysaetos canadensis].	51.37	292	135	3	3	288	32	322	1e-89	282
rs:WP_001539033	bifunctional protein FolD [Escherichia coli].	51.18	297	135	3	1	297	1	287	1e-89	280
rs:WP_025800582	methenyltetrahydrofolate cyclohydrolase [Hafnia alvei].	49.48	291	137	2	1	291	1	281	1e-89	280
sp:FOLD1_MYXXD	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.45	291	146	3	3	292	2	289	1e-89	281
sp:FOLD_SHIDS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.52	297	134	3	1	297	1	287	1e-89	280
rs:WP_001605536	FolD protein [Escherichia coli].	52.25	289	128	3	1	289	1	279	1e-89	280
rs:WP_023489232	bifunctional protein FolD [Serratia sp. DD3].	50.52	291	134	3	1	291	1	281	1e-89	280
rs:WP_025382911	methenyltetrahydrofolate cyclohydrolase [Yersinia similis].	51.20	291	132	3	1	291	1	281	1e-89	280
tr:A0A094NT30_9AVES	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFZ69536.1}; Flags: Fragment;	50.85	295	138	3	3	291	3	296	1e-89	281
rs:WP_021851425	bifunctional protein FolD [Prevotella sp. CAG:1058].	45.92	294	158	1	1	294	1	293	1e-89	281
rs:WP_000729175	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Escherichia].	52.08	288	128	3	1	288	1	278	1e-89	280
sp:FOLD_EDWI9	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.69	290	133	3	1	290	1	280	1e-89	280
rs:WP_038642299	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas sp. OCN003].	50.69	290	133	3	1	290	1	280	1e-89	280
rs:WP_014610292	methenyltetrahydrofolate cyclohydrolase [Shewanella putrefaciens].	49.48	291	137	2	1	291	1	281	1e-89	280
rs:WP_013925964	5,10-methylene-tetrahydrofolate dehydrogenase [Runella slithyformis].	45.36	291	159	0	4	294	2	292	1e-89	281
rs:WP_016855023	methenyltetrahydrofolate cyclohydrolase [Halomonas smyrnensis].	50.52	291	132	4	1	290	1	280	1e-89	280
rs:WP_026696666	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus chagannorensis].	48.65	296	141	3	1	296	1	285	1e-89	280
rs:WP_003459914	methenyltetrahydrofolate cyclohydrolase [Pseudomonas pseudoalcaligenes].	50.69	290	133	2	1	290	1	280	1e-89	280
rs:WP_013048925	5,10-methylene-tetrahydrofolate dehydrogenase [Aminobacterium colombiense].	50.17	291	134	2	1	291	1	280	1e-89	280
tr:Q4F8H3_DANRE	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:AAZ15231.1};	50.51	297	140	3	3	293	30	325	1e-89	282
rs:WP_041122834	5,10-methylene-tetrahydrofolate cyclohydrolase [Jeotgalibacillus alimentarius].	49.14	291	135	3	1	291	1	278	1e-89	280
sp:FOLD_GEOTN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.20	291	131	4	1	291	1	280	1e-89	280
rs:WP_021759273	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio gigas].	49.13	289	140	2	5	293	3	284	1e-89	281
sp:FOLD_DESAG	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.52	287	135	2	5	291	3	282	1e-89	280
rs:WP_021671022	tetrahydrofolate dehydrogenase [Prevotella sp. F0091].	45.24	294	160	1	1	294	1	293	1e-89	280
rs:WP_021016795	hypothetical protein [Serratia sp. ATCC 39006].	50.52	291	134	3	1	291	1	281	1e-89	280
rs:WP_035607525	methenyltetrahydrofolate cyclohydrolase [Edwardsiella tarda].	50.34	290	134	3	1	290	1	280	1e-89	280
rs:WP_006081122	methenyltetrahydrofolate cyclohydrolase [Shewanella baltica].	49.83	291	136	2	1	291	1	281	1e-89	280
rs:WP_007173908	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella bergensis].	47.28	294	154	1	1	294	1	293	1e-89	280
tr:A0A067RE48_ZOONE	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:KDR21308.1};	49.50	299	144	3	1	293	36	333	1e-89	283
rs:WP_000225829	methenyltetrahydrofolate cyclohydrolase [Salmonella bongori].	52.08	288	128	3	1	288	1	278	1e-89	280
rs:WP_014703365	methenyltetrahydrofolate cyclohydrolase [Methylophaga frappieri].	50.00	290	135	2	1	290	1	280	2e-89	280
sp:FOLD_SHEPC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.14	291	138	2	1	291	1	281	2e-89	280
sp:FOLD_CALS8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	53.02	281	119	5	11	288	1	271	2e-89	280
sp:FOLD_CYAP7	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.28	290	144	2	2	291	5	288	2e-89	281
rs:WP_010151122	5,10-methylene-tetrahydrofolate dehydrogenase [SAR324 cluster bacterium JCVI-SC AAA005].	49.82	285	141	1	5	289	4	286	2e-89	281
rs:WP_017642802	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. 313].	48.80	291	139	2	1	291	1	281	2e-89	280
sp:FOLD_PROA2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.59	290	150	1	5	292	3	292	2e-89	280
sp:FOLD_YERE8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.20	291	132	3	1	291	1	281	2e-89	280
rs:WP_015504095	methylenetetrahydrofolate dehydrogenase [Candidatus Methanomethylophilus alvus].	48.11	291	150	1	1	291	1	290	2e-89	280
rs:WP_032295034	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	52.08	288	128	3	1	288	1	278	2e-89	280
rs:WP_028449904	methenyltetrahydrofolate cyclohydrolase [Chitinibacter tainanensis].	50.88	285	130	3	1	285	1	275	2e-89	280
rs:WP_040670662	5,10-methylene-tetrahydrofolate cyclohydrolase [Nitritalea halalkaliphila].	47.96	294	153	0	1	294	1	294	2e-89	280
rs:WP_004379852	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella oulorum].	47.42	291	152	1	4	294	2	291	2e-89	280
rs:WP_018860488	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio].	52.08	288	128	2	1	288	1	278	2e-89	280
rs:WP_027405189	methenyltetrahydrofolate cyclohydrolase [Aquaspirillum serpens].	50.34	290	134	2	1	290	1	280	2e-89	280
rs:XP_007572178	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Poecilia formosa].	51.36	294	136	3	3	290	30	322	2e-89	282
rs:XP_006006556	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Latimeria chalumnae].	52.20	295	134	4	3	291	33	326	2e-89	282
rs:WP_024850764	methenyltetrahydrofolate cyclohydrolase [Thiomicrospira kuenenii].	49.13	289	137	2	1	289	1	279	2e-89	280
rs:WP_006921571	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio magneticus].	49.83	293	141	1	5	297	3	289	2e-89	280
rs:XP_002757646	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Callithrix jacchus].	51.53	295	136	3	3	291	37	330	2e-89	282
sp:FOLD_ERWT9	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.00	292	136	3	1	292	1	282	2e-89	280
rs:WP_036621769	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus macerans].	51.55	291	130	3	1	291	1	280	2e-89	280
rs:WP_013012110	tetrahydrofolate dehydrogenase [Denitrovibrio acetiphilus].	50.34	292	134	2	2	293	3	283	2e-89	280
rs:WP_004571021	5,10-methylene-tetrahydrofolate dehydrogenase [Polaribacter irgensii].	49.83	287	144	0	5	291	3	289	2e-89	280
rs:WP_014678152	tetrahydrofolate dehydrogenase [Streptococcus mutans].	50.69	290	133	3	4	293	3	282	2e-89	280
rs:WP_010194874	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus sp. m3-13].	50.69	290	133	3	1	290	1	280	2e-89	280
rs:WP_019007247	5,10-methylene-tetrahydrofolate dehydrogenase [Cohnella laeviribosi].	50.87	289	131	3	1	289	1	278	2e-89	280
rs:WP_005502209	methenyltetrahydrofolate cyclohydrolase [Shewanella benthica].	48.97	290	138	2	1	290	1	280	2e-89	280
rs:XP_012719036	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Fundulus heteroclitus].	51.36	294	136	3	3	290	30	322	2e-89	282
sp:FOLD_BREBN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.00	292	135	4	1	292	1	281	2e-89	280
rs:WP_039025899	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	52.08	288	128	3	1	288	1	278	2e-89	280
rs:WP_021581339	FolD protein [Escherichia coli].	52.43	288	127	3	1	288	1	278	2e-89	280
rs:WP_043710625	methenyltetrahydrofolate cyclohydrolase [Myxococcus fulvus].	48.45	291	146	3	3	292	2	289	2e-89	280
rs:XP_004544704	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Maylandia zebra].	52.04	294	134	4	3	290	30	322	2e-89	282
rs:WP_021545107	FolD protein [Escherichia coli].	51.90	289	129	3	1	289	1	279	2e-89	280
rs:WP_034132332	5,10-methylene-tetrahydrofolate cyclohydrolase [Peptococcaceae bacterium BICA1-8].	49.31	290	136	3	1	290	1	279	2e-89	280
rs:XP_001687783	AGAP004677-PA [Anopheles gambiae str. PEST].	48.64	294	144	3	3	290	107	399	2e-89	284
rs:WP_005494870	methylenetetrahydrofolate dehydrogenase [Pseudoalteromonas luteoviolacea].	50.52	291	134	3	1	291	1	281	2e-89	280
tr:A0A090X3D9_9FLAO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.38	266	132	0	26	291	1	266	2e-89	280
rs:WP_035348116	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus ginsengihumi].	51.54	293	131	4	1	293	1	282	2e-89	280
rs:WP_035262304	methenyltetrahydrofolate cyclohydrolase [Desulfonatronum lacustre].	48.23	282	139	2	5	286	2	276	2e-89	280
rs:WP_014774122	5,10-methylene-tetrahydrofolate dehydrogenase [Belliella baltica].	49.31	290	147	0	5	294	3	292	2e-89	280
rs:WP_008899252	methenyltetrahydrofolate cyclohydrolase [Rheinheimera sp. A13L].	50.17	291	135	3	1	291	1	281	2e-89	280
rs:WP_008930707	methenyltetrahydrofolate cyclohydrolase [Ectothiorhodospira sp. PHS-1].	50.34	292	135	2	1	292	1	282	2e-89	280
rs:WP_022988052	methenyltetrahydrofolate cyclohydrolase [Marinobacter sp. ES-1].	51.21	289	131	2	1	289	1	279	2e-89	280
rs:WP_043545859	methenyltetrahydrofolate cyclohydrolase [Achromobacter sp. RTa].	50.34	292	134	3	1	292	1	281	2e-89	280
sp:MTDC_BOVIN	RecName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; Includes: RecName: Full=NAD-dependent methylenetetrahydrofolate dehydrogenase; EC=1.5.1.15; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Flags: Precursor;	52.20	295	134	3	3	291	37	330	2e-89	282
tr:A0A068RAP5_9ENTR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.34	290	134	3	1	290	1	280	2e-89	280
sp:FOLD_PELPB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.93	290	147	3	5	291	3	291	2e-89	280
rs:WP_006365859	5,10-methylene-tetrahydrofolate dehydrogenase [Chlorobium ferrooxidans].	48.62	290	145	3	5	291	3	291	2e-89	280
rs:XP_007890160	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Callorhinchus milii].	51.01	298	139	3	2	293	40	336	2e-89	281
rs:WP_021561209	FolD protein [Escherichia coli].	52.08	288	128	3	1	288	1	278	2e-89	280
rs:WP_046961015	methenyltetrahydrofolate cyclohydrolase [Dehalococcoides sp. UCH007].	48.63	292	149	1	1	292	1	291	2e-89	280
rs:WP_036970015	bifunctional protein FolD [Proteus mirabilis].	49.48	291	137	3	1	291	1	281	2e-89	280
rs:WP_043954535	methenyltetrahydrofolate cyclohydrolase [Enterobacter sp. YD4].	51.89	291	130	3	1	291	1	281	2e-89	280
rs:WP_026258415	methenyltetrahydrofolate cyclohydrolase [Endozoicomonas elysicola].	50.52	289	133	2	1	289	1	279	2e-89	280
rs:WP_029715869	hypothetical protein [Atribacteria bacterium JGI 0000079-L04].	50.17	291	138	1	1	291	1	284	2e-89	280
rs:WP_005277034	methenyltetrahydrofolate cyclohydrolase [Yersinia bercovieri].	50.52	291	134	3	1	291	1	281	2e-89	280
rs:WP_035593433	methenyltetrahydrofolate cyclohydrolase [Halomonas salina].	49.66	290	136	2	1	290	1	280	2e-89	280
rs:XP_007950817	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Orycteropus afer afer].	51.84	299	137	3	3	295	37	334	3e-89	282
rs:WP_024967336	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. IMH].	50.34	290	134	3	1	290	1	280	3e-89	280
rs:WP_010249696	5,10-methylene-tetrahydrofolate dehydrogenase [Acetivibrio cellulolyticus].	49.48	289	135	3	1	289	1	278	3e-89	280
tr:M4ATI2_XIPMA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSXMAP00000017777};	51.02	294	137	3	3	290	37	329	3e-89	281
rs:WP_018345006	5,10-methylene-tetrahydrofolate dehydrogenase [Cytophaga aurantiaca].	47.90	286	149	0	4	289	2	287	3e-89	280
rs:WP_033788854	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. FF5].	51.38	290	131	3	1	290	1	280	3e-89	280
rs:WP_026676258	5,10-methylene-tetrahydrofolate cyclohydrolase [Fictibacillus gelatini].	48.97	292	138	3	1	292	1	281	3e-89	280
rs:WP_046458612	methenyltetrahydrofolate cyclohydrolase [Hafnia alvei].	49.48	291	137	2	1	291	1	281	3e-89	280
rs:WP_002776802	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter].	51.72	290	128	5	5	293	3	281	3e-89	280
rs:WP_010490217	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. S9].	49.31	290	137	2	1	290	1	280	3e-89	280
rs:WP_029890430	methenyltetrahydrofolate cyclohydrolase [Polycyclovorans algicola].	49.48	291	136	3	1	291	1	280	3e-89	280
rs:WP_006893282	methylenetetrahydrofolate dehydrogenase [Salmonella enterica].	52.43	288	127	3	1	288	1	278	3e-89	280
rs:WP_009119248	methenyltetrahydrofolate cyclohydrolase [Neisseria shayeganii].	51.40	286	129	2	1	286	1	276	3e-89	280
rs:WP_018174676	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio].	51.74	288	129	2	1	288	1	278	3e-89	280
rs:WP_013327027	5,10-methylene-tetrahydrofolate dehydrogenase [Sulfurimonas autotrophica].	50.52	287	132	3	4	290	2	278	3e-89	280
rs:WP_013346108	methenyltetrahydrofolate cyclohydrolase [Ferrimonas balearica].	49.14	291	138	2	1	291	1	281	3e-89	280
rs:XP_006031206	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Alligator sinensis].	50.16	305	139	4	3	295	39	342	3e-89	282
rs:WP_010618498	methenyltetrahydrofolate cyclohydrolase [Plautia stali symbiont].	50.86	291	133	3	1	291	1	281	3e-89	280
rs:WP_028486841	methenyltetrahydrofolate cyclohydrolase [Thiomicrospira chilensis].	49.13	289	137	2	1	289	1	279	3e-89	280
rs:XP_010828037	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Bison bison bison].	52.54	295	133	3	3	291	37	330	3e-89	282
rs:XP_006625422	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Lepisosteus oculatus].	50.85	295	138	3	3	291	30	323	3e-89	281
rs:WP_001415800	bifunctional protein FolD [Escherichia coli].	51.18	297	135	3	1	297	1	287	3e-89	280
rs:WP_037392197	methenyltetrahydrofolate cyclohydrolase [Snodgrassella alvi].	50.34	290	134	3	1	290	1	280	3e-89	280
rs:WP_015407018	methylenetetrahydrofolate dehydrogenase [Dehalococcoides mccartyi].	48.63	292	149	1	1	292	1	291	3e-89	280
gp:ECU82664_126	methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase [Escherichia coli]	51.18	297	135	3	1	297	1	287	3e-89	280
rs:WP_024612305	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas haloplanktis].	51.20	291	132	3	1	291	1	281	3e-89	280
rs:WP_015009912	5,10-methylene-tetrahydrofolate dehydrogenase [Amphibacillus xylanus].	48.79	289	137	3	1	289	1	278	3e-89	280
rs:XP_008639821	PREDICTED: LOW QUALITY PROTEIN: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Corvus brachyrhynchos].	50.50	299	141	3	3	295	60	357	3e-89	282
rs:XP_012586899	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Condylura cristata].	51.86	295	135	3	3	291	23	316	3e-89	281
rs:WP_035666256	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus akibai].	51.38	290	129	3	1	290	1	278	3e-89	279
rs:WP_023246737	bifunctional protein FolD [Salmonella enterica].	51.74	288	129	3	1	288	1	278	3e-89	280
sp:FOLD_SULDN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.87	287	131	3	4	290	2	278	3e-89	279
rs:WP_025748871	methenyltetrahydrofolate cyclohydrolase [Shigella flexneri].	52.08	288	128	3	1	288	1	278	3e-89	280
rs:WP_023485509	methylenetetrahydrofolate dehydrogenase [Paenibacillus larvae].	48.81	295	140	3	1	295	1	284	3e-89	280
sp:FOLD_DEHMC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.12	293	151	1	1	293	1	292	3e-89	280
rs:WP_042546584	methenyltetrahydrofolate cyclohydrolase [Yersinia aldovae].	50.86	291	133	3	1	291	1	281	3e-89	280
rs:WP_043526213	methenyltetrahydrofolate cyclohydrolase [Halomonas xinjiangensis].	48.62	290	139	2	1	290	1	280	3e-89	280
rs:WP_039056142	methenyltetrahydrofolate cyclohydrolase [Enterobacter sp. Bisph1].	51.89	291	130	3	1	291	1	281	3e-89	280
rs:WP_026681112	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus megaterium].	49.31	290	136	3	1	290	1	279	3e-89	279
rs:WP_041330800	methenyltetrahydrofolate cyclohydrolase [Dehalococcoides mccartyi].	48.63	292	149	1	1	292	1	291	3e-89	280
rs:XP_006045485	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Bubalus bubalis].	52.54	295	133	3	3	291	65	358	3e-89	283
tr:I5C1I5_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.96	294	153	0	1	294	15	308	3e-89	280
rs:WP_004382633	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella veroralis].	45.92	294	158	1	1	294	1	293	3e-89	280
rs:WP_035608031	methenyltetrahydrofolate cyclohydrolase [Hylemonella gracilis].	51.37	292	131	4	1	292	1	281	3e-89	279
rs:WP_044780761	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter jejuni].	50.69	290	131	5	5	293	3	281	3e-89	279
rs:WP_032258796	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	51.18	297	135	3	1	297	1	287	3e-89	279
rs:XP_005795027	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Xiphophorus maculatus].	51.02	294	137	3	3	290	30	322	3e-89	281
rs:WP_045152971	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	51.18	297	135	3	1	297	1	287	3e-89	279
rs:WP_034004132	bifunctional protein FolD [Pseudomonas aeruginosa].	49.66	290	136	2	1	290	1	280	3e-89	279
rs:XP_005722182	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Pundamilia nyererei].	52.04	294	134	4	3	290	30	322	3e-89	281
rs:WP_035720940	5,10-methylene-tetrahydrofolate cyclohydrolase [Gracilibacillus boraciitolerans].	48.63	292	138	4	1	291	1	281	3e-89	279
rs:WP_010636806	methenyltetrahydrofolate cyclohydrolase [Acidithiobacillus thiooxidans].	48.81	293	140	2	1	293	1	283	3e-89	279
rs:WP_044140995	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus pumilus].	48.12	293	141	4	1	293	1	282	3e-89	279
rs:WP_038137071	methenyltetrahydrofolate cyclohydrolase [Thiomicrospira sp. Milos-T1].	50.17	289	134	2	1	289	1	279	3e-89	279
rs:WP_022077919	bifunctional protein FolD [Clostridium sp. CAG:571].	49.66	290	135	4	3	292	2	280	3e-89	279
rs:WP_019943302	5,10-methylene-tetrahydrofolate dehydrogenase [Dyadobacter beijingensis].	46.05	291	157	0	4	294	2	292	3e-89	280
rs:WP_045640711	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacteriales bacterium BRH_c54].	49.30	286	145	0	5	290	4	289	3e-89	280
rs:WP_003021887	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Enterobacteriaceae].	52.08	288	128	3	1	288	1	278	3e-89	279
tr:D7Y5Q3_ECOLX	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EFJ97030.1}; Flags: Fragment;	51.52	297	134	3	1	297	67	353	4e-89	281
rs:XP_010629845	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Fukomys damarensis].	51.17	299	139	3	3	295	68	365	4e-89	283
rs:WP_008174575	methenyltetrahydrofolate cyclohydrolase [Marinobacter manganoxydans].	49.31	290	137	2	1	290	1	280	4e-89	279
rs:WP_006646407	methenyltetrahydrofolate cyclohydrolase [Photobacterium sp. SKA34].	52.58	291	128	2	1	291	1	281	4e-89	279
rs:WP_003847497	5,10-methylene-tetrahydrofolate dehydrogenase [Citrobacter freundii].	52.08	288	128	3	1	288	1	278	4e-89	279
rs:WP_002642135	methenyltetrahydrofolate cyclohydrolase [Simonsiella muelleri].	53.77	292	125	3	1	292	1	282	4e-89	279
rs:WP_000729156	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	52.08	288	128	3	1	288	1	278	4e-89	279
rs:WP_042525579	methenyltetrahydrofolate cyclohydrolase [Coxiella burnetii].	47.24	290	143	2	1	290	1	280	4e-89	279
rs:WP_001692323	bifunctional protein FolD [Escherichia coli].	51.18	297	135	3	1	297	1	287	4e-89	279
rs:WP_043331302	methenyltetrahydrofolate cyclohydrolase [Cobetia marina].	49.66	290	136	2	1	290	1	280	4e-89	279
tr:M3ZBK0_NOMLE	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSNLEP00000024087};	51.53	295	136	3	3	291	37	330	4e-89	281
rs:WP_003089324	tetrahydrofolate dehydrogenase [Streptococcus ratti].	51.03	290	132	3	4	293	3	282	4e-89	279
rs:WP_019212809	methenyltetrahydrofolate cyclohydrolase [Yersinia massiliensis].	50.86	291	133	3	1	291	1	281	4e-89	279
rs:WP_008879806	5,10-methylene-tetrahydrofolate dehydrogenase [Geobacillus sp. G11MC16].	51.20	291	131	4	1	291	1	280	4e-89	279
rs:WP_036874452	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella buccalis].	47.77	291	151	1	4	294	2	291	4e-89	279
rs:WP_028117512	methenyltetrahydrofolate cyclohydrolase [Ferrimonas senticii].	48.45	291	140	3	1	291	1	281	4e-89	279
rs:WP_043927842	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus licheniformis].	49.83	293	136	3	1	293	1	282	4e-89	279
rs:WP_043756172	methenyltetrahydrofolate cyclohydrolase [Thiorhodococcus sp. AK35].	50.34	290	134	3	1	290	1	280	4e-89	279
rs:WP_005295193	bifunctional protein FolD [Edwardsiella tarda].	50.34	290	134	3	1	290	1	280	4e-89	279
rs:WP_025367244	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio thiocyanoxidans].	51.04	288	131	2	1	288	1	278	4e-89	279
rs:WP_043015477	methenyltetrahydrofolate cyclohydrolase [Citrobacter freundii].	52.08	288	128	3	1	288	1	278	4e-89	279
rs:WP_027182497	bifunctional protein FolD [Desulfovibrio alaskensis].	50.17	287	136	2	5	291	3	282	4e-89	279
rs:WP_007373630	methenyltetrahydrofolate cyclohydrolase [Kosakonia radicincitans].	51.89	291	130	3	1	291	1	281	4e-89	279
rs:WP_047256390	methenyltetrahydrofolate cyclohydrolase [Moellerella wisconsensis].	49.83	291	136	3	1	291	1	281	4e-89	279
rs:WP_018692810	methenyltetrahydrofolate cyclohydrolase [Algicola sagamiensis].	51.20	291	132	3	1	291	1	281	4e-89	279
rs:WP_004348373	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella buccalis].	47.77	291	151	1	4	294	2	291	4e-89	279
sp:FOLD_DESAD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.97	290	141	2	4	293	2	284	4e-89	279
rs:WP_001736952	bifunctional protein FolD [Escherichia coli].	52.08	288	128	3	1	288	1	278	4e-89	279
rs:WP_031571740	methenyltetrahydrofolate cyclohydrolase [Rheinheimera texasensis].	49.48	291	137	3	1	291	1	281	4e-89	279
rs:WP_043765516	methenyltetrahydrofolate cyclohydrolase [Algiphilus aromaticivorans].	50.00	290	135	2	1	290	1	280	4e-89	279
sp:FOLD_SALAR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.55	291	131	3	1	291	1	281	5e-89	279
rs:XP_004691600	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Condylura cristata].	51.86	295	135	3	3	291	37	330	5e-89	281
rs:XP_005916357	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Haplochromis burtoni].	52.04	294	134	4	3	290	30	322	5e-89	281
rs:WP_031578343	methenyltetrahydrofolate cyclohydrolase [Ruminobacter sp. RM87].	50.00	290	135	2	1	290	1	280	5e-89	279
tr:H9F7V7_MACMU	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:AFE70716.1}; Flags: Fragment;	51.53	295	136	3	3	291	15	308	5e-89	280
rs:WP_042569308	methenyltetrahydrofolate cyclohydrolase [Yersinia intermedia].	50.86	291	133	3	1	291	1	281	5e-89	279
rs:WP_047152939	5,10-methylene-tetrahydrofolate cyclohydrolase [Aneurinibacillus tyrosinisolvens].	48.99	296	133	5	1	293	1	281	5e-89	279
rs:WP_034292161	methenyltetrahydrofolate cyclohydrolase [Alysiella crassa].	50.69	290	133	2	1	290	1	280	5e-89	279
rs:WP_002647659	5,10-methylene-tetrahydrofolate dehydrogenase [Planctomyces maris].	49.31	290	140	1	1	290	1	283	5e-89	279
sp:FOLD_HAEDU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.66	296	140	3	1	296	1	287	5e-89	279
rs:WP_038390666	methenyltetrahydrofolate cyclohydrolase [Salmonella bongori].	52.08	288	128	3	1	288	1	278	5e-89	279
rs:WP_034862843	methenyltetrahydrofolate cyclohydrolase [Enterobacteriaceae bacterium B14].	51.20	291	132	3	1	291	1	281	5e-89	279
tr:W9VCW9_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.34	290	134	3	1	290	11	290	5e-89	279
rs:XP_003451675	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Oreochromis niloticus].	51.70	294	135	4	3	290	30	322	5e-89	281
rs:WP_047060756	methenyltetrahydrofolate cyclohydrolase [Edwardsiella tarda].	50.34	290	134	3	1	290	1	280	5e-89	279
rs:XP_003268734	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Nomascus leucogenys].	51.53	295	136	3	3	291	37	330	5e-89	281
rs:WP_006915468	methenyltetrahydrofolate cyclohydrolase [Salinisphaera shabanensis].	50.00	290	135	3	1	290	1	280	5e-89	279
rs:WP_003451995	methylenetetrahydrofolate dh [Pseudomonas pseudoalcaligenes].	49.66	290	136	2	1	290	1	280	5e-89	279
tr:K2ART0_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.79	289	138	2	1	289	1	279	5e-89	279
rs:XP_004590736	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Ochotona princeps].	51.53	295	136	3	3	291	37	330	5e-89	281
rs:WP_013163062	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfurivibrio alkaliphilus].	47.26	292	153	1	1	292	1	291	5e-89	279
rs:WP_013332100	methenyltetrahydrofolate cyclohydrolase [Halomonas elongata].	49.66	290	136	2	1	290	1	280	5e-89	279
rs:WP_043208414	methenyltetrahydrofolate cyclohydrolase [Bordetella hinzii].	50.51	293	134	3	1	293	1	282	5e-89	279
rs:WP_022532908	bifunctional protein FolD [Methanoculleus sp. CAG:1088].	47.77	291	151	1	1	291	1	290	5e-89	279
rs:WP_039122880	5,10-methylene-tetrahydrofolate cyclohydrolase [Francisella guangzhouensis].	48.10	289	138	3	5	292	3	280	5e-89	279
rs:WP_042874034	methenyltetrahydrofolate cyclohydrolase [Dickeya sp. NCPPB 569].	50.52	291	134	3	1	291	1	281	5e-89	279
rs:WP_033782248	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. 9140].	50.17	291	135	3	1	291	1	281	5e-89	279
rs:WP_032289515	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	52.08	288	128	3	1	288	1	278	5e-89	279
rs:WP_046500637	methenyltetrahydrofolate cyclohydrolase [Filomicrobium sp. Y].	49.15	293	139	2	1	293	1	283	6e-89	279
rs:WP_034319697	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. DW5-4].	47.78	293	142	4	1	293	1	282	6e-89	279
rs:WP_042162675	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. G1].	50.34	292	134	3	1	292	1	281	6e-89	279
rs:WP_015487000	methylenetetrahydrofolate dehydrogenase [Thalassolituus oleivorans].	50.34	290	134	2	1	290	1	280	6e-89	279
rs:WP_020676027	5,10-methylene-tetrahydrofolate dehydrogenase [Geopsychrobacter electrodiphilus].	50.52	291	133	3	1	291	1	280	6e-89	278
rs:XP_005630608	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Canis lupus familiaris].	52.20	295	134	3	3	291	37	330	6e-89	281
rs:WP_028391732	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. FJAT-14515].	49.49	293	137	4	1	293	1	282	6e-89	279
rs:WP_044832572	methenyltetrahydrofolate cyclohydrolase [Thalassomonas actiniarum].	48.80	291	139	2	1	291	1	281	6e-89	278
rs:WP_007473306	5,10-methylene-tetrahydrofolate dehydrogenase [Caminibacter mediatlanticus].	49.30	286	133	3	5	290	3	276	6e-89	278
tr:F9H5C8_HAEHA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	52.99	268	115	2	21	288	3	259	6e-89	278
rs:WP_027987391	hypothetical protein [delta proteobacterium JGI 0002000-E07].	49.67	304	131	3	1	290	1	296	6e-89	279
rs:XP_005897710	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Bos mutus].	52.20	295	134	3	3	291	37	330	6e-89	281
rs:WP_009436113	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella sp. oral taxon 306].	45.92	294	158	1	1	294	1	293	6e-89	279
rs:WP_038184949	5,10-methylene-tetrahydrofolate cyclohydrolase [Viridibacillus arenosi].	50.17	293	135	4	1	293	1	282	6e-89	279
rs:WP_038842885	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter coli].	52.07	290	127	5	5	293	3	281	6e-89	278
gpu:CP011509_4126	Methylenetetrahydrofolate dehydrogenase [Archangium gephyra]	48.77	285	142	3	3	286	2	283	6e-89	279
rs:WP_032955787	methenyltetrahydrofolate cyclohydrolase [Bordetella hinzii].	50.51	293	134	3	1	293	1	282	6e-89	278
rs:XP_003922644	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Saimiri boliviensis boliviensis].	51.53	295	136	3	3	291	37	330	6e-89	281
rs:WP_040044504	methenyltetrahydrofolate cyclohydrolase [Hafnia alvei].	49.14	291	138	2	1	291	1	281	6e-89	278
rs:XP_003908881	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Papio anubis].	51.53	295	136	3	3	291	37	330	6e-89	281
sp:FOLD_DESVH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.78	287	140	2	4	290	2	281	6e-89	278
rs:WP_013450141	tetrahydrofolate dehydrogenase [Calditerrivibrio nitroreducens].	49.14	291	137	2	3	293	2	281	6e-89	278
rs:WP_034873230	methenyltetrahydrofolate cyclohydrolase [Endozoicomonas montiporae].	50.00	290	135	2	1	290	1	280	6e-89	278
rs:WP_046552871	methenyltetrahydrofolate cyclohydrolase [Arsukibacterium sp. MJ3].	50.34	290	134	2	1	290	1	280	7e-89	278
rs:WP_002620436	5,10-methylene-tetrahydrofolate dehydrogenase [Stigmatella aurantiaca].	49.83	291	135	3	3	293	2	281	7e-89	278
rs:WP_005167791	bifunctional protein FolD [Yersinia enterocolitica].	50.86	291	133	3	1	291	1	281	7e-89	279
rs:WP_038854905	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter coli].	52.07	290	127	5	5	293	3	281	7e-89	278
tr:D4F8T8_EDWTA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.34	290	134	3	1	290	6	285	7e-89	279
sp:FOLD_EUBR3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.52	289	132	3	3	291	2	279	7e-89	278
rs:WP_034898441	methenyltetrahydrofolate cyclohydrolase [Erwinia typographi].	50.17	291	135	3	1	291	1	281	7e-89	278
rs:WP_044713333	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	51.90	289	129	3	1	289	1	279	7e-89	278
tr:B1Y6X2_LEPCP	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.85	297	132	3	1	297	1	286	7e-89	279
rs:WP_005709315	methenyltetrahydrofolate cyclohydrolase [Haemophilus paraphrohaemolyticus].	50.51	293	135	2	1	293	1	283	7e-89	278
rs:WP_046478302	methenyltetrahydrofolate cyclohydrolase [Filomicrobium sp. W].	49.15	293	139	2	1	293	1	283	7e-89	279
rs:WP_008105961	methenyltetrahydrofolate cyclohydrolase [Methylophilales bacterium HTCC2181].	49.31	290	136	2	1	290	1	279	7e-89	278
tr:D2HH67_AILME	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EFB18651.1}; Flags: Fragment;	50.85	295	138	3	3	291	8	301	7e-89	280
rs:WP_040814980	methenyltetrahydrofolate cyclohydrolase [gamma proteobacterium HTCC5015].	51.55	291	131	2	1	291	1	281	7e-89	278
rs:WP_039062479	methenyltetrahydrofolate cyclohydrolase [Shigella flexneri].	52.08	288	128	3	1	288	1	278	7e-89	278
rs:WP_013201156	methenyltetrahydrofolate cyclohydrolase [Erwinia billingiae].	50.69	290	133	3	1	290	1	280	7e-89	278
rs:WP_020974843	methylenetetrahydrofolate dehydrogenase [Campylobacter coli].	51.72	290	128	5	5	293	3	281	7e-89	278
rs:WP_014547700	5,10-methylene-tetrahydrofolate dehydrogenase [Francisella tularensis].	47.62	294	142	3	5	297	3	285	8e-89	278
rs:WP_010322978	methenyltetrahydrofolate cyclohydrolase [Marinobacterium stanieri].	51.72	290	130	2	1	290	1	280	8e-89	278
sp:FOLD_BORA1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	295	136	3	1	295	1	284	8e-89	278
sp:FOLD_CHLCH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.28	290	146	3	5	291	3	291	8e-89	279
gp:CP007344_425	methenyltetrahydrofolate cyclohydrolase [Salmonella enterica subsp. enterica serovar Enteritidis str.]	52.08	288	128	3	1	288	1	278	8e-89	278
rs:WP_034039052	methenyltetrahydrofolate cyclohydrolase [Pseudomonas aeruginosa].	49.31	290	137	2	1	290	1	280	8e-89	278
rs:WP_027955440	5,10-methylene-tetrahydrofolate cyclohydrolase [Halobacillus kuroshimensis].	50.52	291	132	3	1	291	1	279	8e-89	278
rs:WP_019018382	methenyltetrahydrofolate cyclohydrolase [Halomonas lutea].	50.00	290	135	2	1	290	1	280	8e-89	278
rs:WP_017827221	methenyltetrahydrofolate cyclohydrolase [Proteus mirabilis].	49.48	291	137	3	1	291	1	281	8e-89	278
rs:WP_010456255	methenyltetrahydrofolate cyclohydrolase [Succinivibrionaceae bacterium WG-1].	48.96	288	137	2	1	288	1	278	8e-89	278
rs:XP_007083512	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Panthera tigris altaica].	50.85	295	138	3	3	291	38	331	9e-89	280
rs:WP_028772351	methenyltetrahydrofolate cyclohydrolase [Shewanella waksmanii].	49.14	291	138	2	1	291	1	281	9e-89	278
rs:WP_018403667	methenyltetrahydrofolate cyclohydrolase [Marinobacter lipolyticus].	51.03	290	132	2	1	290	1	280	9e-89	278
tr:B5JWZ1_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.55	291	131	2	1	291	31	311	9e-89	279
rs:WP_021997075	bifunctional protein FolD [Clostridium sp. CAG:780].	49.83	289	134	4	4	292	3	280	9e-89	278
rs:WP_027270323	methenyltetrahydrofolate cyclohydrolase [Legionella sainthelensi].	50.87	289	132	2	1	289	1	279	9e-89	278
rs:WP_034792241	methenyltetrahydrofolate cyclohydrolase [Ewingella americana].	50.17	291	135	2	1	291	1	281	9e-89	278
rs:WP_026765106	5,10-methylene-tetrahydrofolate cyclohydrolase [Sediminibacterium salmoneum].	48.94	284	145	0	5	288	3	286	9e-89	278
rs:WP_005122057	methenyltetrahydrofolate cyclohydrolase [Citrobacter sp. CIP 55.13].	52.08	288	128	3	1	288	1	278	9e-89	278
rs:WP_033752629	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. NGS-ED-1003].	51.03	290	132	3	1	290	1	280	9e-89	278
rs:WP_018909607	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella veroralis].	45.58	294	159	1	1	294	1	293	9e-89	278
rs:WP_015462158	MULTISPECIES: methylenetetrahydrofolate dehydrogenase [Edwardsiella].	50.34	290	134	3	1	290	1	280	9e-89	278
rs:WP_045472262	methenyltetrahydrofolate cyclohydrolase [Thioploca ingrica].	48.62	290	139	2	1	290	1	280	9e-89	278
rs:WP_008951449	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Alishewanella].	51.72	290	130	3	1	290	1	280	9e-89	278
tr:A0A023EN06_AEDAL	SubName: Full=Putative c1-tetrahydrofolate synthase {ECO:0000313|EMBL:JAC10768.1};	50.17	295	139	4	3	290	2	295	1e-88	279
rs:XP_009896132	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Picoides pubescens].	49.50	299	144	3	3	295	5	302	1e-88	279
rs:XP_006872468	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Chrysochloris asiatica].	51.17	299	139	3	3	295	37	334	1e-88	280
rs:WP_036882063	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas sp. COT-239 OH1446].	47.22	288	152	0	4	291	7	294	1e-88	278
tr:D0ZCJ1_EDWTE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.34	290	134	3	1	290	6	285	1e-88	278
rs:WP_021182321	methylenetetrahydrofolate dehydrogenase [Pantoea sp. AS-PWVM4].	50.86	291	133	3	1	291	1	281	1e-88	278
rs:WP_019246117	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Alistipes marseilloanorexicus].	48.80	291	147	1	4	294	2	290	1e-88	278
rs:XP_007432674	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Python bivittatus].	49.83	299	143	3	3	295	59	356	1e-88	281
rs:WP_039330566	methenyltetrahydrofolate cyclohydrolase [Pantoea rodasii].	50.17	291	135	3	1	291	1	281	1e-88	278
rs:WP_032979606	methenyltetrahydrofolate cyclohydrolase [Bordetella hinzii].	50.17	293	135	3	1	293	1	282	1e-88	278
rs:WP_016390713	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Cycloclasticus].	49.31	290	137	3	1	290	1	280	1e-88	278
rs:WP_025329872	methenyltetrahydrofolate cyclohydrolase [Snodgrassella alvi].	50.69	290	133	3	1	290	1	280	1e-88	278
rs:WP_046489841	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavobacteriaceae bacterium ASP10-09a].	48.08	287	149	0	5	291	3	289	1e-88	278
rs:WP_038831474	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter coli].	52.07	290	127	5	5	293	3	281	1e-88	278
rs:XP_009820376	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Gavia stellata].	51.34	298	138	3	3	294	3	299	1e-88	278
tr:W5PS05_SHEEP	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOARP00000013234};	52.88	295	132	3	3	291	37	330	1e-88	280
rs:WP_044900266	5,10-methylene-tetrahydrofolate cyclohydrolase [Aeribacillus pallidus].	49.32	292	137	4	1	292	1	281	1e-88	278
rs:WP_031572360	methenyltetrahydrofolate cyclohydrolase [Acidithiobacillus thiooxidans].	48.81	293	140	2	1	293	1	283	1e-88	278
rs:WP_012777177	methenyltetrahydrofolate cyclohydrolase [Photorhabdus asymbiotica].	48.80	291	139	2	1	291	1	281	1e-88	278
sp:FOLD_PROMH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.14	291	138	3	1	291	1	281	1e-88	278
rs:WP_018077605	methenyltetrahydrofolate cyclohydrolase [Thiobacillus denitrificans].	49.83	289	135	2	1	289	1	279	1e-88	278
rs:WP_021884036	bifunctional protein FolD [Ruminococcus sp. CAG:108].	52.61	287	126	3	4	290	2	278	1e-88	278
rs:WP_018249968	hypothetical protein [Orenia marismortui].	52.08	288	126	4	4	291	7	282	1e-88	278
rs:WP_018749248	hypothetical protein [Chitiniphilus shinanonensis].	51.05	286	128	4	1	285	1	275	1e-88	278
rs:WP_015254840	5,10-methylene-tetrahydrofolate dehydrogenase [Thermobacillus composti].	50.86	291	132	3	1	291	1	280	1e-88	278
rs:WP_037950168	5,10-methylene-tetrahydrofolate cyclohydrolase [Sulfuricurvum sp. MLSB].	49.13	287	136	2	4	290	2	278	1e-88	278
rs:WP_023131164	FolD protein [Pseudomonas aeruginosa].	49.31	290	137	2	1	290	1	280	1e-88	278
rs:WP_032616914	methenyltetrahydrofolate cyclohydrolase [Leclercia adecarboxylata].	52.58	291	128	3	1	291	1	281	1e-88	278
rs:XP_003984183	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Felis catus].	50.85	295	138	3	3	291	37	330	1e-88	280
rs:WP_022026299	bifunctional protein FolD [Clostridium sp. CAG:75].	51.90	289	128	4	3	291	2	279	1e-88	278
rs:WP_015516564	bifunctional protein FolD [Eubacterium rectale CAG:36].	50.52	289	132	3	3	291	2	279	1e-88	278
rs:WP_043219839	methenyltetrahydrofolate cyclohydrolase [Pseudomonas balearica].	49.48	291	137	2	1	291	1	281	1e-88	278
rs:WP_028576434	methenyltetrahydrofolate cyclohydrolase [Desulfomicrobium escambiense].	51.58	285	127	3	4	288	2	275	1e-88	278
tr:A0A093EY16_GAVST	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFV46759.1}; Flags: Fragment;	51.34	298	138	3	3	294	4	300	1e-88	278
rs:WP_021688094	tetrahydrofolate dehydrogenase [Treponema lecithinolyticum].	47.60	292	150	2	1	292	1	289	1e-88	278
rs:WP_023056793	MULTISPECIES: tetrahydrofolate dehydrogenase [Prevotella].	47.42	291	152	1	4	294	2	291	1e-88	278
rs:WP_027720298	methenyltetrahydrofolate cyclohydrolase [Desulfovibrio zosterae].	48.28	290	143	2	4	293	2	284	1e-88	278
rs:WP_005844389	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Prevotellaceae].	45.86	290	156	1	5	294	4	292	1e-88	278
tr:A0A087T9I1_9ARAC	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:KFM61770.1}; Flags: Fragment;	51.54	293	135	3	3	289	54	345	1e-88	281
rs:WP_007154042	methenyltetrahydrofolate cyclohydrolase [Marinobacter algicola].	49.14	291	138	2	1	291	1	281	1e-88	278
rs:WP_044600585	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter coli].	51.38	290	129	5	5	293	3	281	1e-88	278
rs:WP_002800030	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter coli].	51.38	290	129	5	5	293	3	281	1e-88	278
sp:FOLD_FRATN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.92	288	138	3	5	291	3	279	1e-88	278
rs:WP_042359095	5,10-methylene-tetrahydrofolate cyclohydrolase [Geomicrobium sp. JCM 19055].	48.45	291	138	3	1	291	1	279	1e-88	278
rs:WP_021885487	bifunctional protein FolD [Clostridium sp. CAG:590].	50.52	287	131	3	3	289	2	277	1e-88	278
rs:WP_013508199	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. At-9b].	50.86	291	133	3	1	291	1	281	1e-88	278
rs:WP_003450083	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas].	49.31	290	137	2	1	290	1	280	1e-88	278
rs:WP_018931664	hypothetical protein [Gracilibacillus lacisalsi].	47.95	292	141	3	1	292	1	281	1e-88	278
rs:WP_027853916	methenyltetrahydrofolate cyclohydrolase [Marinobacterium litorale].	53.68	285	122	3	6	290	12	286	1e-88	278
rs:XP_008416810	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Poecilia reticulata].	51.70	294	135	4	3	290	30	322	1e-88	280
rs:WP_022504995	bifunctional protein FolD [Eubacterium sp. CAG:581].	53.82	288	122	4	3	290	2	278	1e-88	278
rs:WP_042109603	methenyltetrahydrofolate cyclohydrolase [Escherichia coli].	51.52	297	132	4	1	297	1	285	2e-88	278
rs:WP_041419969	methenyltetrahydrofolate cyclohydrolase [Shewanella violacea].	48.97	290	138	2	1	290	1	280	2e-88	278
rs:WP_003387260	methylenetetrahydrofolate dehydrogenase [Brevibacillus borstelensis].	50.17	291	134	4	1	291	1	280	2e-88	278
tr:A0A074VFW7_9NEIS	SubName: Full=5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:KEQ01350.1}; Flags: Fragment;	50.34	290	134	3	1	290	31	310	2e-88	279
rs:XP_007189078	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Balaenoptera acutorostrata scammoni].	51.19	295	137	3	3	291	37	330	2e-88	280
gp:AY659410_1	PA1796 [synthetic construct]	49.31	290	137	2	1	290	1	280	2e-88	278
rs:XP_012307620	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Aotus nancymaae].	51.53	295	136	3	3	291	37	330	2e-88	280
rs:WP_003098026	methenyltetrahydrofolate cyclohydrolase [Pseudomonas aeruginosa].	49.31	290	137	2	1	290	1	280	2e-88	277
rs:WP_026099358	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorothrix hollandica].	51.41	284	132	2	3	286	10	287	2e-88	278
sp:FOLD_PSEA8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.31	290	137	2	1	290	1	280	2e-88	277
rs:WP_012135999	methylenetetrahydrofolate dehydrogenase [Marinobacter lipolyticus].	48.97	290	138	2	1	290	1	280	2e-88	277
sp:FOLD_DEHMB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.29	292	150	1	1	292	1	291	2e-88	278
rs:WP_013134718	5,10-methylene-tetrahydrofolate dehydrogenase [Arcobacter nitrofigilis].	50.35	286	132	3	5	290	3	278	2e-88	277
tr:G3P055_GASAC	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGACP00000010978};	50.33	300	141	4	3	295	30	328	2e-88	279
rs:XP_002811942	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Pongo abelii].	51.19	295	137	3	3	291	37	330	2e-88	280
tr:A0A0C7BAV9_9FUNG	SubName: Full=RMATCC62417_04247 protein {ECO:0000313|EMBL:CEG67893.1};	48.30	294	145	3	1	291	25	314	2e-88	279
rs:WP_028900772	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella timonensis].	47.40	289	151	1	6	294	4	291	2e-88	278
rs:XP_002921529	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Ailuropoda melanoleuca].	50.85	295	138	3	3	291	37	330	2e-88	280
rs:WP_041047197	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. VKM B-2647].	50.00	286	132	3	1	286	1	275	2e-88	278
rs:WP_038833952	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter coli].	51.72	290	128	5	5	293	3	281	2e-88	277
rs:WP_004248636	bifunctional protein FolD [Proteus mirabilis].	49.14	291	138	3	1	291	1	281	2e-88	278
rs:WP_041645301	methenyltetrahydrofolate cyclohydrolase [Marinobacter adhaerens].	49.83	289	135	2	1	289	1	279	2e-88	277
rs:WP_031567289	methenyltetrahydrofolate cyclohydrolase [Legionella wadsworthii].	48.79	289	138	2	1	289	1	279	2e-88	277
rs:WP_003041689	bifunctional protein FolD [Francisella tularensis].	47.92	288	138	3	5	291	3	279	2e-88	277
rs:WP_027001518	5,10-methylene-tetrahydrofolate cyclohydrolase [Flexibacter roseolus].	47.02	285	151	0	4	288	2	286	2e-88	278
rs:WP_026499844	5,10-methylene-tetrahydrofolate cyclohydrolase [Caldibacillus debilis].	50.86	291	132	4	1	291	1	280	2e-88	277
rs:WP_037993853	5,10-methylene-tetrahydrofolate cyclohydrolase [Thermoactinomyces sp. Gus2-1].	48.45	291	139	4	1	291	1	280	2e-88	277
rs:WP_032137740	methenyltetrahydrofolate cyclohydrolase [Kingella sp. Sch538].	50.00	290	135	2	1	290	1	280	2e-88	277
rs:WP_041124514	5,10-methylene-tetrahydrofolate cyclohydrolase [Sulfurovum sp. FS06-10].	49.66	290	136	2	4	293	2	281	2e-88	277
rs:WP_016523773	hypothetical protein [Treponema medium].	47.22	288	147	2	3	290	2	284	2e-88	278
rs:WP_040202456	5,10-methylene-tetrahydrofolate cyclohydrolase [Geoalkalibacter subterraneus].	49.83	289	134	3	3	291	2	279	2e-88	277
rs:WP_034025464	methenyltetrahydrofolate cyclohydrolase [Pseudomonas aeruginosa].	49.31	290	137	2	1	290	1	280	2e-88	277
rs:WP_037053043	methenyltetrahydrofolate cyclohydrolase [Pseudomonas oleovorans].	50.00	290	135	2	1	290	1	280	2e-88	277
rs:WP_009876250	bifunctional protein FolD [Pseudomonas aeruginosa].	49.31	290	137	2	1	290	1	280	2e-88	277
rs:WP_036682821	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus].	49.14	291	137	3	1	291	1	280	2e-88	277
tr:J1YE11_9ALTE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.72	290	130	3	1	290	22	301	2e-88	278
sp:FOLD_CAMHC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.97	290	137	3	4	293	2	280	2e-88	277
rs:WP_015854341	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Dickeya].	51.20	291	132	3	1	291	1	281	2e-88	277
gp:CP007292_332	methenyltetrahydrofolate cyclohydrolase [Salmonella enterica subsp. enterica serovar Enteritidis str.]	51.74	288	129	3	1	288	1	278	2e-88	277
rs:WP_044640382	5,10-methylene-tetrahydrofolate cyclohydrolase [Thermoactinomycetaceae bacterium GD1].	49.66	294	137	3	3	296	2	284	2e-88	277
rs:WP_002651070	5,10-methylene-tetrahydrofolate dehydrogenase [Blastopirellula marina].	49.49	295	137	2	1	290	1	288	2e-88	277
rs:XP_004277138	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Orcinus orca].	51.19	295	137	3	3	291	37	330	2e-88	279
gp:AY871996_1	hypothetical protein [synthetic construct]	47.80	295	141	4	5	297	29	312	2e-88	278
rs:WP_014658834	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter cetorum].	46.18	288	145	2	5	292	8	285	2e-88	277
rs:WP_045162129	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	50.69	290	133	2	1	290	1	280	2e-88	277
rs:WP_017627899	bifunctional protein FolD [Proteus mirabilis].	49.14	291	138	3	1	291	1	281	2e-88	277
rs:WP_007894634	tetrahydrofolate dehydrogenase [Streptococcus pseudoporcinus].	49.48	289	136	2	5	293	4	282	2e-88	277
rs:WP_024893789	methenyltetrahydrofolate cyclohydrolase [Acidithiobacillus thiooxidans].	48.46	293	141	2	1	293	1	283	2e-88	277
rs:XP_004006137	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Ovis aries].	52.88	295	132	3	3	291	65	358	2e-88	280
sp:FOLD_FRAT1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.92	288	138	3	5	291	3	279	2e-88	277
tr:K1Y2B1_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.18	285	139	2	5	288	3	285	3e-88	277
rs:WP_034828233	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Enterobacteriaceae].	50.52	291	134	3	1	291	1	281	3e-88	277
rs:WP_029197147	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus alginolyticus].	49.32	292	137	3	1	292	1	281	3e-88	277
rs:WP_034912914	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Erwinia].	49.83	291	136	3	1	291	1	281	3e-88	277
rs:WP_043066139	5,10-methylene-tetrahydrofolate cyclohydrolase [Aneurinibacillus migulanus].	51.37	292	131	4	1	292	1	281	3e-88	277
rs:WP_028387651	methenyltetrahydrofolate cyclohydrolase [Legionella fairfieldensis].	48.11	291	141	2	1	291	1	281	3e-88	277
rs:WP_008249910	5,10-methylene-tetrahydrofolate dehydrogenase [Limnobacter sp. MED105].	48.12	293	141	3	1	293	1	282	3e-88	277
rs:WP_004260235	methenyltetrahydrofolate cyclohydrolase [Providencia rettgeri].	49.83	291	136	3	1	291	1	281	3e-88	277
rs:WP_009174862	methenyltetrahydrofolate cyclohydrolase [Neisseria sp. oral taxon 014].	49.66	290	136	2	1	290	1	280	3e-88	277
rs:WP_005468871	tetrahydrofolate dehydrogenase [Porphyromonas catoniae].	44.60	287	159	0	5	291	8	294	3e-88	277
rs:WP_002826972	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter coli].	51.38	290	129	5	5	293	3	281	3e-88	277
rs:WP_029579489	methenyltetrahydrofolate cyclohydrolase [Bordetella hinzii].	50.17	293	135	3	1	293	1	282	3e-88	277
rs:WP_043704661	methenyltetrahydrofolate cyclohydrolase, partial [Leptothrix cholodnii].	52.23	291	128	3	1	291	1	280	3e-88	277
tr:E4PF71_MARAH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.83	289	135	2	1	289	16	294	3e-88	277
rs:WP_041105433	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	49.14	291	138	2	1	291	1	281	3e-88	277
rs:XP_793717	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Strongylocentrotus purpuratus].	50.00	300	142	4	1	293	27	325	3e-88	279
rs:WP_041362481	methenyltetrahydrofolate cyclohydrolase [Methylovorus sp. MP688].	50.35	288	133	2	1	288	1	278	3e-88	277
rs:WP_015279610	5,10-methylene-tetrahydrofolate dehydrogenase [Thioflavicoccus mobilis].	50.00	288	134	2	1	288	1	278	3e-88	277
rs:WP_045836247	methenyltetrahydrofolate cyclohydrolase [Hyphomicrobium sp. 99].	50.51	293	135	2	1	293	1	283	3e-88	278
tr:A0A060WGH1_ONCMY	SubName: Full=Oncorhynchus mykiss genomic scaffold, scaffold_266 {ECO:0000313|EMBL:CDQ66217.1};	51.19	295	137	3	3	291	30	323	3e-88	279
rs:XP_001418654	predicted protein [Ostreococcus lucimarinus CCE9901].	47.47	297	150	2	1	295	1	293	3e-88	277
rs:WP_008984201	methenyltetrahydrofolate cyclohydrolase [Alishewanella agri].	51.38	290	131	3	1	290	1	280	3e-88	277
rs:WP_033953586	bifunctional protein FolD [Pseudomonas aeruginosa].	48.97	290	138	2	1	290	1	280	3e-88	277
rs:WP_014549389	bifunctional protein FolD [Francisella tularensis].	47.57	288	139	3	5	291	3	279	3e-88	277
rs:WP_028300066	methenyltetrahydrofolate cyclohydrolase [Oceanospirillum beijerinckii].	48.45	291	140	2	1	291	1	281	3e-88	277
rs:WP_046371597	5,10-methylene-tetrahydrofolate cyclohydrolase [Flavihumibacter petaseus].	48.08	287	149	0	4	290	2	288	3e-88	277
rs:XP_010730831	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Larimichthys crocea].	50.67	300	140	4	3	295	30	328	3e-88	279
tr:T1E6F1_CROHD	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like protein {ECO:0000313|EMBL:JAA97663.1};	50.17	297	141	3	3	293	44	339	3e-88	279
rs:WP_022663296	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio longus].	52.10	286	130	2	5	290	4	282	3e-88	277
rs:WP_021622931	tetrahydrofolate dehydrogenase [Aneurinibacillus aneurinilyticus].	51.37	292	131	4	1	292	1	281	3e-88	277
rs:WP_022580302	methenyltetrahydrofolate cyclohydrolase [Pseudomonas aeruginosa].	49.31	290	137	2	1	290	1	280	3e-88	277
rs:WP_002225712	methenyltetrahydrofolate cyclohydrolase [Neisseria meningitidis].	50.87	289	132	2	1	289	1	279	3e-88	277
tr:F6X034_CIOIN	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCINP00000005743}; Flags: Fragment;	52.94	289	129	3	11	293	1	288	3e-88	277
rs:WP_033537662	methenyltetrahydrofolate cyclohydrolase [Shewanella sp. ECSMB14101].	49.83	291	136	3	1	291	1	281	3e-88	277
rs:XP_009012999	hypothetical protein HELRODRAFT_109971 [Helobdella robusta].	50.51	293	139	3	3	293	34	322	3e-88	279
rs:WP_014473493	5,10-methylene-tetrahydrofolate dehydrogenase [Arcobacter sp. L].	48.60	286	137	3	5	290	3	278	3e-88	277
rs:WP_044408347	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. FeS53a].	49.31	290	137	2	1	290	1	280	3e-88	277
rs:WP_033989683	methenyltetrahydrofolate cyclohydrolase [Pseudomonas aeruginosa].	49.31	290	137	2	1	290	1	280	3e-88	277
rs:WP_036855708	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella amnii].	46.60	294	156	1	1	294	1	293	3e-88	277
sp:FOLD_SHELP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.52	291	134	3	1	291	1	281	3e-88	276
rs:WP_004913518	5,10-methylene-tetrahydrofolate dehydrogenase [Providencia rettgeri].	49.83	291	136	3	1	291	1	281	3e-88	277
rs:WP_025820074	methenyltetrahydrofolate cyclohydrolase [Shewanella marina].	49.14	291	138	2	1	291	1	281	3e-88	277
rs:WP_010527815	5,10-methylene-tetrahydrofolate dehydrogenase [Thermophagus xiamenensis].	47.57	288	151	0	4	291	2	289	3e-88	277
rs:WP_017346791	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. A4].	49.83	291	136	3	1	291	1	281	3e-88	277
rs:WP_012781748	5,10-methylene-tetrahydrofolate dehydrogenase [Flavobacteriaceae bacterium 3519-10].	46.58	292	155	1	3	294	2	292	3e-88	277
tr:K7T472_9NEIS	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.69	290	133	3	1	290	17	296	4e-88	277
rs:WP_040373421	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus psychrosaccharolyticus].	49.32	292	137	4	1	292	1	281	4e-88	276
rs:WP_043072718	5,10-methylene-tetrahydrofolate cyclohydrolase [Aneurinibacillus migulanus].	51.37	292	131	4	1	292	1	281	4e-88	277
rs:XP_007518997	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Erinaceus europaeus].	52.20	295	134	3	3	291	37	330	4e-88	279
rs:WP_015698191	methenyltetrahydrofolate cyclohydrolase [Rahnella aquatilis].	49.83	291	136	3	1	291	1	281	4e-88	277
rs:WP_035297945	5,10-methylene-tetrahydrofolate cyclohydrolase [Brevibacillus thermoruber].	49.32	292	137	4	1	292	1	281	4e-88	276
rs:WP_026587808	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. NSP9.1].	48.81	293	139	3	1	293	1	282	4e-88	276
rs:WP_016194632	methylenetetrahydrofolate dehydrogenase [Arcticibacter svalbardensis].	45.89	292	158	0	4	295	2	293	4e-88	277
rs:WP_020681374	methenyltetrahydrofolate cyclohydrolase [Marinobacterium rhizophilum].	49.48	291	137	2	1	291	1	281	4e-88	276
tr:D4ZAC5_SHEVD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.97	290	138	2	1	290	26	305	4e-88	277
rs:WP_045467141	methenyltetrahydrofolate cyclohydrolase [Burkholderiales bacterium GJ-E10].	49.15	293	138	3	1	293	1	282	4e-88	276
rs:WP_028319185	methenyltetrahydrofolate cyclohydrolase [Desulfobulbus elongatus].	47.60	292	152	1	1	292	1	291	4e-88	277
rs:WP_035545238	5,10-methylene-tetrahydrofolate cyclohydrolase [Halobacillus sp. BBL2006].	49.83	291	134	3	1	291	1	279	4e-88	276
rs:WP_006394400	5,10-methylene-tetrahydrofolate dehydrogenase [Achromobacter insuavis].	49.66	292	136	3	1	292	1	281	4e-88	276
tr:A0A093G814_PICPB	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFV65273.1}; Flags: Fragment;	49.83	295	141	3	3	291	3	296	4e-88	277
rs:WP_027590377	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonadaceae].	49.14	291	138	2	1	291	1	281	4e-88	276
rs:WP_022101241	tetrahydrofolate dehydrogenase [Prevotella sp. CAG:5226].	47.93	290	150	1	1	290	1	289	4e-88	276
rs:WP_040186935	methenyltetrahydrofolate cyclohydrolase [Halomonas salina].	49.83	289	135	2	1	289	1	279	4e-88	276
rs:WP_032726131	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus subtilis].	48.46	293	140	4	1	293	1	282	4e-88	276
rs:WP_004954407	methenyltetrahydrofolate cyclohydrolase [Serratia odorifera].	49.14	291	138	3	1	291	1	281	4e-88	276
rs:WP_020927317	methylenetetrahydrofolate dehydrogenase [Achromobacter xylosoxidans].	49.66	292	136	3	1	292	1	281	4e-88	276
rs:WP_022117268	bifunctional protein FolD [Clostridium sp. CAG:169].	48.44	289	138	4	3	291	2	279	4e-88	276
rs:WP_006387483	5,10-methylene-tetrahydrofolate dehydrogenase [Achromobacter xylosoxidans].	49.32	292	137	3	1	292	1	281	4e-88	276
rs:WP_037289373	5,10-methylene-tetrahydrofolate cyclohydrolase [Saccharibacillus sacchari].	50.17	291	134	4	2	292	3	282	4e-88	276
rs:WP_007042479	methenyltetrahydrofolate cyclohydrolase [Thiorhodococcus drewsii].	50.00	290	135	2	1	290	1	280	4e-88	276
rs:WP_008232423	methylenetetrahydrofolate dehydrogenase [Richelia intracellularis].	48.42	285	141	2	2	286	5	283	4e-88	276
tr:G7PMI7_MACFA	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EHH55682.1};	51.19	295	137	3	3	291	37	330	4e-88	279
rs:WP_028384426	methenyltetrahydrofolate cyclohydrolase [Legionella moravica].	47.60	292	143	2	1	292	1	282	4e-88	276
rs:WP_018285248	methenyltetrahydrofolate cyclohydrolase [zeta proteobacterium SCGC AB-133-C04].	47.95	292	142	2	2	293	6	287	4e-88	276
rs:WP_021943083	bifunctional protein FolD [Clostridium sp. CAG:632].	51.04	288	130	4	3	290	2	278	5e-88	276
rs:WP_021889915	bifunctional protein FolD [Succinatimonas sp. CAG:777].	50.51	297	132	5	1	293	1	286	5e-88	276
rs:WP_002218206	methenyltetrahydrofolate cyclohydrolase [Neisseria meningitidis].	50.87	289	132	2	1	289	1	279	5e-88	276
rs:WP_006872709	methenyltetrahydrofolate cyclohydrolase [Legionella drancourtii].	48.79	289	138	2	1	289	1	279	5e-88	276
tr:K2ESX6_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.10	289	140	2	1	289	1	279	5e-88	276
rs:WP_006045214	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella pallens].	47.28	294	154	1	1	294	1	293	5e-88	276
rs:WP_026835708	methenyltetrahydrofolate cyclohydrolase [Eubacterium xylanophilum].	52.45	286	122	3	3	288	2	273	5e-88	276
rs:WP_004437724	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus methanolicus].	49.66	290	135	4	1	290	1	279	5e-88	276
rs:WP_003033095	5,10-methylene-tetrahydrofolate dehydrogenase [Francisella tularensis].	47.92	288	138	3	5	291	3	279	5e-88	276
sp:FOLD_SHEPW	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.45	291	140	3	1	291	1	281	5e-88	276
rs:WP_035525490	methenyltetrahydrofolate cyclohydrolase [Burkholderia sacchari].	52.92	291	126	3	1	291	1	280	5e-88	277
rs:WP_019339162	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	50.34	290	134	2	1	290	1	280	5e-88	276
rs:WP_015810715	5,10-methylene-tetrahydrofolate dehydrogenase [Dyadobacter fermentans].	45.70	291	158	0	4	294	2	292	5e-88	276
rs:WP_027131209	methenyltetrahydrofolate cyclohydrolase [Gemmatimonadetes bacterium SCGC AAA240-J22].	48.29	292	150	1	1	291	1	292	5e-88	276
rs:WP_044896387	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus alveayuensis].	50.51	293	134	4	1	293	1	282	5e-88	276
rs:WP_012926175	5,10-methylene-tetrahydrofolate dehydrogenase [Spirosoma linguale].	45.21	292	160	0	4	295	2	293	5e-88	276
rs:WP_015238581	methylenetetrahydrofolate dehydrogenase [Candidatus Kinetoplastibacterium crithidii].	49.15	293	138	3	1	293	1	282	5e-88	276
gp:CP002252_76	Methylenetetrahydrofolate dehydrogenase (NADP(+)) [Methylovorus sp. MP688]	50.35	288	133	2	1	288	18	295	5e-88	277
rs:WP_046526388	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. SA2-6].	50.51	293	134	3	1	293	1	282	5e-88	276
rs:WP_028081522	methenyltetrahydrofolate cyclohydrolase [Solimonas soli].	51.39	288	130	3	1	288	1	278	5e-88	276
tr:A0A093J660_EURHL	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFW10450.1}; Flags: Fragment;	51.01	298	139	3	3	294	4	300	5e-88	277
rs:WP_017444479	methenyltetrahydrofolate cyclohydrolase [Gayadomonas joobiniege].	50.17	291	135	2	1	291	1	281	5e-88	276
rs:WP_002611730	methenyltetrahydrofolate cyclohydrolase [Stigmatella aurantiaca].	49.31	290	137	2	1	290	1	280	5e-88	276
rs:WP_015829111	methenyltetrahydrofolate cyclohydrolase [Methylovorus glucosotrophus].	50.35	288	133	2	1	288	1	278	5e-88	276
rs:WP_006209374	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus vortex].	51.38	290	130	4	2	291	3	281	5e-88	276
rs:WP_042910218	methenyltetrahydrofolate cyclohydrolase [Pseudomonas aeruginosa].	49.31	290	137	2	1	290	1	280	5e-88	276
rs:WP_035404048	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. SJS].	50.51	293	134	4	1	293	1	282	5e-88	276
sp:FOLD_NEIMB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.87	289	132	2	1	289	1	279	5e-88	276
rs:WP_020966081	methylenetetrahydrofolate dehydrogenase [Treponema pedis].	48.29	292	148	2	1	292	1	289	5e-88	276
tr:D4L7T3_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	52.26	287	127	3	4	290	2	278	6e-88	276
tr:G2HI94_PANTR	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:BAK63452.1};	51.19	295	137	3	3	291	31	324	6e-88	278
tr:A0A023ERE2_AEDAL	SubName: Full=Putative c1-tetrahydrofolate synthase {ECO:0000313|EMBL:JAC11221.1};	50.17	295	139	4	3	290	40	333	6e-88	278
sp:FOLD1_THICR	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.79	289	138	2	1	289	1	279	6e-88	276
rs:WP_022975176	methenyltetrahydrofolate cyclohydrolase [Nevskia ramosa].	51.03	290	132	2	2	291	9	288	6e-88	276
rs:WP_044232217	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas sp. COT-290 OH3588].	46.53	288	154	0	4	291	7	294	6e-88	276
rs:WP_031652941	methenyltetrahydrofolate cyclohydrolase [Pseudomonas aeruginosa].	49.31	290	137	2	1	290	1	280	6e-88	276
rs:WP_041509381	methenyltetrahydrofolate cyclohydrolase [Shewanella sp. cp20].	50.52	291	134	3	1	291	1	281	6e-88	276
rs:WP_013576534	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Rahnella].	49.48	291	137	3	1	291	1	281	6e-88	276
rs:XP_008698234	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Ursus maritimus].	50.85	295	138	3	3	291	37	330	6e-88	278
rs:XP_010127056	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Chlamydotis macqueenii].	51.01	298	139	3	3	294	3	299	6e-88	276
rs:WP_014455660	5,10-methylene-tetrahydrofolate dehydrogenase [Spirochaeta africana].	47.40	289	148	2	1	289	1	285	6e-88	276
rs:WP_029099473	5,10-methylene-tetrahydrofolate cyclohydrolase [Brevibacillus thermoruber].	49.32	292	137	4	1	292	1	281	6e-88	276
rs:WP_045659426	5,10-methylene-tetrahydrofolate cyclohydrolase [Clostridiaceae bacterium BRH_c20a].	48.62	290	138	3	1	290	1	279	6e-88	276
rs:WP_044186688	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas sp. COT-290 OH860].	46.18	288	155	0	4	291	7	294	6e-88	276
rs:WP_006298599	5,10-methylene-tetrahydrofolate dehydrogenase [Hylemonella gracilis].	50.17	293	135	4	1	293	1	282	6e-88	276
rs:WP_022736169	5,10-methylene-tetrahydrofolate dehydrogenase [Laceyella sacchari].	51.20	291	130	4	1	291	1	279	6e-88	276
rs:XP_005686510	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Capra hircus].	53.22	295	131	3	3	291	91	384	7e-88	280
rs:WP_019036183	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella amnii].	46.26	294	157	1	1	294	1	293	7e-88	276
rs:XP_005965260	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Pantholops hodgsonii].	52.54	295	133	3	3	291	37	330	7e-88	278
rs:WP_039032577	methenyltetrahydrofolate cyclohydrolase [Leclercia adecarboxylata].	52.94	289	126	3	1	289	1	279	7e-88	276
rs:WP_042129810	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus].	48.80	291	138	3	1	291	1	280	7e-88	276
sp:FOLD_NITMU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.68	292	133	3	1	292	1	281	7e-88	276
rs:WP_042103920	hypothetical protein [Parachlamydiaceae bacterium HS-T3].	45.83	288	152	2	5	291	2	286	7e-88	276
rs:WP_028489440	methenyltetrahydrofolate cyclohydrolase [Thiothrix lacustris].	50.85	295	134	3	1	294	1	285	7e-88	276
tr:A0A091L0W0_9GRUI	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFP45922.1}; Flags: Fragment;	51.01	298	139	3	3	294	4	300	7e-88	276
rs:WP_013255006	5,10-methylene-tetrahydrofolate dehydrogenase [Spirochaeta smaragdinae].	48.48	297	152	1	1	297	1	296	7e-88	276
rs:WP_022050615	bifunctional protein FolD [Ruminococcus sp. CAG:254].	50.00	288	134	2	3	290	2	279	8e-88	276
sp:FOLD_NEIMA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.87	289	132	2	1	289	1	279	8e-88	276
rs:XP_001654868	AAEL010751-PA, partial [Aedes aegypti].	50.85	295	136	5	3	290	4	296	8e-88	276
rs:WP_006884030	5,10-methylene-tetrahydrofolate dehydrogenase [Halosimplex carlsbadense].	50.35	286	140	2	4	289	3	286	8e-88	276
rs:WP_004364444	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella nigrescens].	46.94	294	155	1	1	294	1	293	8e-88	276
tr:K2ADZ5_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.13	289	137	2	1	289	1	279	8e-88	276
rs:WP_042427395	5,10-methylene-tetrahydrofolate cyclohydrolase [Geomicrobium sp. JCM 19039].	49.31	290	136	3	1	290	1	279	8e-88	276
rs:WP_002243677	methenyltetrahydrofolate cyclohydrolase [Neisseria meningitidis].	50.52	289	133	2	1	289	1	279	8e-88	276
rs:XP_003810401	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Pan paniscus].	51.19	295	137	3	3	291	37	330	9e-88	278
sp:FOLD_SHEPA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.14	291	138	3	1	291	1	281	9e-88	276
rs:WP_015359138	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Ruminiclostridium].	48.29	292	140	3	1	292	1	281	9e-88	276
tr:R7TMV7_CAPTE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELT95208.1, ECO:0000313|EnsemblMetazoa:CapteP197433};	50.17	297	141	3	3	293	15	310	9e-88	276
rs:WP_003153164	MULTISPECIES: bifunctional protein FolD [Bacillus subtilis group].	47.78	293	142	4	1	293	1	282	9e-88	275
rs:WP_038503343	methenyltetrahydrofolate cyclohydrolase [Achromobacter xylosoxidans].	49.32	292	137	3	1	292	1	281	9e-88	275
rs:WP_034234446	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium AC2029].	51.22	287	129	3	3	289	2	277	9e-88	275
rs:WP_026752551	5,10-methylene-tetrahydrofolate cyclohydrolase [Sediminibacterium sp. C3].	49.30	284	144	0	5	288	3	286	9e-88	276
rs:WP_022351720	bifunctional protein FolD [Firmicutes bacterium CAG:534].	48.96	288	136	3	4	291	3	279	9e-88	275
rs:WP_020613412	5,10-methylene-tetrahydrofolate dehydrogenase [Spirochaeta bajacaliforniensis].	48.80	291	148	1	1	291	1	290	9e-88	276
rs:WP_046330261	methenyltetrahydrofolate cyclohydrolase [Polynucleobacter necessarius].	49.15	295	139	3	1	295	1	284	9e-88	276
rs:WP_003680350	methenyltetrahydrofolate cyclohydrolase [Neisseria flavescens].	50.86	291	129	3	1	289	1	279	9e-88	275
rs:WP_027981467	methenyltetrahydrofolate cyclohydrolase [gamma proteobacterium L18].	48.97	290	138	2	1	290	1	280	1e-87	275
rs:WP_002233241	methenyltetrahydrofolate cyclohydrolase [Neisseria meningitidis].	50.87	289	132	2	1	289	1	279	1e-87	275
rs:WP_021208888	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	49.31	290	137	2	1	290	1	280	1e-87	275
rs:XP_007459458	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Lipotes vexillifer].	50.85	295	138	3	3	291	37	330	1e-87	278
rs:WP_046161234	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. 10B238].	50.00	290	135	2	1	290	1	280	1e-87	275
rs:WP_039027358	methenyltetrahydrofolate cyclohydrolase [Pseudomonas aeruginosa].	49.31	290	137	2	1	290	1	280	1e-87	275
rs:WP_025761521	5,10-methylene-tetrahydrofolate cyclohydrolase [Dyadobacter tibetensis].	44.67	291	161	0	4	294	2	292	1e-87	276
rs:WP_045833122	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. BL1].	50.17	291	135	3	1	291	1	281	1e-87	275
rs:WP_036649877	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus pini].	50.34	292	134	4	1	292	1	281	1e-87	275
rs:WP_015653876	5,10-methylene-tetrahydrofolate dehydrogenase [uncultured Sulfuricurvum sp. RIFRC-1].	49.13	287	136	2	4	290	2	278	1e-87	275
rs:WP_017755724	hypothetical protein [Bacillus sp. ZYK].	50.00	292	135	3	1	292	1	281	1e-87	275
tr:A0A0D6HBX0_ALCXX	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:CKH28966.1};	49.32	292	137	3	1	292	1	281	1e-87	275
rs:WP_003683785	methenyltetrahydrofolate cyclohydrolase [Neisseria flavescens].	50.86	291	129	3	1	289	1	279	1e-87	275
sp:FOLD_FRATM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.92	288	138	3	5	291	3	279	1e-87	275
rs:WP_036492600	methenyltetrahydrofolate cyclohydrolase [Neisseria mucosa].	51.20	291	128	3	1	289	1	279	1e-87	275
tr:I2AXP2_FRANT	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:AFJ42939.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AFJ42939.1};	49.31	288	134	3	5	291	289	565	1e-87	284
rs:WP_031389718	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. KNHs209].	51.59	283	126	4	4	286	3	274	1e-87	275
rs:XP_007968376	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Chlorocebus sabaeus].	51.53	295	136	3	3	291	154	447	1e-87	281
tr:G9KBN6_MUSPF	SubName: Full=Methylenetetrahydrofolate dehydrogenase 2, methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:AES02311.1}; Flags: Fragment;	50.51	295	139	3	3	291	3	296	1e-87	276
tr:A0A0D1AFY9_9SPHN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.00	288	134	2	3	290	7	284	1e-87	276
sp:FOLD_MAGSM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.03	290	132	2	3	292	2	281	1e-87	275
rs:WP_027725828	5,10-methylene-tetrahydrofolate cyclohydrolase [Tuberibacillus calidus].	49.31	290	136	3	1	290	1	279	1e-87	275
tr:B2R7W0_HUMAN	SubName: Full=cDNA, FLJ93628, Homo sapiens methylene tetrahydrofolate dehydrogenase (NAD+dependent), methenyltetrahydrofolate cyclohydrolase (MTHFD2),nuclear gene encoding mitochondrial protein, mRNA {ECO:0000313|EMBL:BAG35957.1};	51.19	295	137	3	3	291	31	324	1e-87	277
rs:WP_042527868	methenyltetrahydrofolate cyclohydrolase [Yersinia ruckeri].	50.17	291	135	3	1	291	1	281	1e-87	275
tr:K1ZU40_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.08	291	144	2	3	293	2	282	1e-87	275
rs:WP_045750452	methenyltetrahydrofolate cyclohydrolase [Methylophilaceae bacterium MMS-10A-171].	49.31	288	136	2	1	288	1	278	1e-87	275
tr:A0A069DHN1_9BACL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.00	292	135	4	1	292	1	281	1e-87	275
rs:WP_028900509	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella sp. HJM029].	47.08	291	153	1	4	294	2	291	1e-87	275
rs:WP_003079501	tetrahydrofolate dehydrogenase [Streptococcus macacae].	48.97	290	138	2	4	293	3	282	1e-87	275
rs:WP_036716331	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus darwinianus].	50.17	291	134	3	1	291	1	280	1e-87	275
rs:WP_043905425	5,10-methylene-tetrahydrofolate cyclohydrolase [Geobacillus stearothermophilus].	50.00	294	136	4	1	294	1	283	1e-87	275
rs:WP_024962166	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter ureolyticus].	52.26	287	126	3	5	291	3	278	1e-87	275
sp:FOLD_THIDA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.44	289	139	2	1	289	1	279	1e-87	275
rs:WP_015775387	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfomicrobium baculatum].	50.70	284	129	2	5	288	3	275	1e-87	275
rs:WP_036205063	methenyltetrahydrofolate cyclohydrolase [Marinobacter sp. MCTG268].	49.14	291	138	2	1	291	1	281	1e-87	275
rs:WP_008320642	5,10-methylene-tetrahydrofolate dehydrogenase [Haloferax mucosum].	50.00	288	142	2	5	292	4	289	1e-87	275
rs:WP_041053509	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus subtilis].	48.12	293	141	4	1	293	1	282	1e-87	275
rs:WP_022182345	bifunctional protein FolD [Clostridium sp. CAG:575].	48.28	290	139	3	3	292	2	280	1e-87	275
sp:FOLD_METMA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.14	291	137	2	3	293	8	287	2e-87	275
rs:WP_039074439	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. MSP13].	48.12	293	141	4	1	293	1	282	2e-87	275
rs:WP_045816357	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. SM3].	50.17	291	135	3	1	291	1	281	2e-87	275
rs:WP_024328729	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio sp. ALR17-21].	50.69	288	132	2	1	288	1	278	2e-87	275
tr:U6DIR7_NEOVI	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:CCP82007.1}; Flags: Fragment;	50.85	295	138	3	3	291	22	315	2e-87	276
rs:WP_022427786	bifunctional protein FolD [Ruminococcus sp. CAG:403].	49.48	289	136	2	3	291	2	280	2e-87	275
rs:WP_028554190	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. URHA0014].	48.97	292	138	3	1	292	1	281	2e-87	275
rs:WP_019640974	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio sp. ALSr1].	50.35	288	133	2	1	288	1	278	2e-87	275
rs:WP_014114365	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus subtilis group].	48.12	293	141	4	1	293	1	282	2e-87	275
rs:WP_033986637	methenyltetrahydrofolate cyclohydrolase [Pseudomonas aeruginosa].	48.97	290	138	2	1	290	1	280	2e-87	275
rs:WP_029270045	5,10-methylene-tetrahydrofolate cyclohydrolase [Virgibacillus alimentarius].	48.28	290	139	3	1	290	1	279	2e-87	275
tr:W4QKL0_9BACI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.45	291	138	3	1	291	2	280	2e-87	275
sp:MTDC_HUMAN	RecName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; Includes: RecName: Full=NAD-dependent methylenetetrahydrofolate dehydrogenase; EC=1.5.1.15; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Flags: Precursor;	51.19	295	137	3	3	291	37	330	2e-87	277
gp:CP000109_724	Methenyltetrahydrofolate cyclohydrolase [Thiomicrospira crunogena XCL-2]	48.79	289	138	2	1	289	26	304	2e-87	276
rs:WP_003677188	methenyltetrahydrofolate cyclohydrolase [Neisseria cinerea].	51.21	289	131	2	1	289	1	279	2e-87	275
rs:WP_022325457	bifunctional protein FolD [Clostridium sp. CAG:798].	49.48	289	135	4	3	291	2	279	2e-87	275
rs:WP_046351386	methenyltetrahydrofolate cyclohydrolase [Janthinobacterium sp. B9-8].	51.92	287	126	5	1	286	1	276	2e-87	275
rs:WP_035346109	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus hemicellulosilyticus].	48.45	291	138	3	1	291	1	279	2e-87	275
rs:WP_045427489	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. MT-1].	50.00	290	135	2	1	290	1	280	2e-87	275
rs:WP_010334889	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus mojavensis].	48.12	293	141	4	1	293	1	282	2e-87	275
rs:WP_005601101	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Butyrivibrio].	51.23	285	131	4	3	286	2	279	2e-87	275
rs:WP_033166433	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. KNHs205].	51.72	290	129	3	4	293	3	281	2e-87	275
rs:WP_039698443	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus equinus].	50.17	291	135	3	3	293	2	282	2e-87	275
rs:WP_032874053	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus amyloliquefaciens].	47.78	293	142	4	1	293	1	282	2e-87	275
rs:WP_021953333	bifunctional protein FolD [Eubacterium sp. CAG:161].	51.06	284	128	4	3	286	2	274	2e-87	275
rs:WP_037491005	methenyltetrahydrofolate cyclohydrolase [Snodgrassella alvi].	49.31	290	137	3	1	290	1	280	2e-87	275
sp:FOLD_PELLD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.24	290	151	1	5	292	3	292	2e-87	275
rs:WP_013247403	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Nitrospira defluvii].	48.80	291	139	2	1	291	1	281	2e-87	275
rs:WP_036836901	methenyltetrahydrofolate cyclohydrolase [Photorhabdus temperata].	50.52	291	134	2	1	291	1	281	2e-87	275
rs:WP_003226403	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus].	48.12	293	141	4	1	293	1	282	2e-87	275
rs:WP_029460328	methenyltetrahydrofolate cyclohydrolase [Desulfovibrio alcoholivorans].	50.51	297	137	2	5	297	3	293	2e-87	275
sp:FOLD_TRIEI	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.82	281	135	2	6	286	5	279	2e-87	275
rs:WP_028694427	methenyltetrahydrofolate cyclohydrolase [Pseudomonas cremoricolorata].	48.45	291	140	2	1	291	1	281	2e-87	275
sp:FOLD_BACA2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.78	293	142	4	1	293	1	282	2e-87	275
rs:WP_036636766	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. FSL R5-808].	51.38	290	130	4	2	291	3	281	2e-87	275
rs:WP_004230774	tetrahydrofolate dehydrogenase [Streptococcus equinus].	50.17	291	135	3	3	293	2	282	2e-87	275
rs:WP_034421471	hypothetical protein [Clostridiales bacterium DRI-13].	49.65	288	134	3	1	288	1	277	2e-87	275
gp:CP000096_897	5,10-methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [Chlorobium luteolum DSM 273]	47.24	290	151	1	5	292	15	304	2e-87	275
sp:FOLD_BACSU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.12	293	141	4	1	293	1	282	2e-87	275
rs:WP_025241931	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	49.66	290	136	2	1	290	1	280	2e-87	275
rs:WP_014305398	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus amyloliquefaciens].	47.78	293	142	4	1	293	1	282	2e-87	275
rs:WP_008371865	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. M47T1].	49.31	290	137	2	1	290	1	280	2e-87	275
rs:WP_022780210	5,10-methylene-tetrahydrofolate dehydrogenase [Lachnospiraceae bacterium NK4A136].	51.41	284	127	3	3	286	2	274	2e-87	275
rs:WP_041067617	methenyltetrahydrofolate cyclohydrolase [Thiolapillus brandeum].	49.15	295	140	2	1	295	1	285	2e-87	275
rs:WP_046680205	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. DMB20].	48.80	291	138	3	1	291	1	280	2e-87	275
rs:WP_014480234	methenyltetrahydrofolate cyclohydrolase [Bacillus subtilis].	48.12	293	141	4	1	293	1	282	2e-87	275
rs:WP_006527852	5,10-methylene-tetrahydrofolate dehydrogenase [Gloeocapsa sp. PCC 73106].	48.59	284	140	2	3	286	6	283	2e-87	275
rs:WP_003035598	5,10-methylene-tetrahydrofolate dehydrogenase [Francisella tularensis].	47.57	288	139	3	5	291	3	279	2e-87	275
rs:WP_019790276	tetrahydrofolate dehydrogenase [Streptococcus sobrinus].	49.15	293	140	2	1	293	1	284	2e-87	275
rs:WP_021220497	methenyltetrahydrofolate cyclohydrolase [Pseudomonas alcaligenes].	48.97	290	138	2	1	290	1	280	2e-87	275
rs:WP_009095514	methenyltetrahydrofolate cyclohydrolase [Halomonas sp. GFAJ-1].	47.77	291	142	2	1	291	1	281	2e-87	275
rs:WP_016952906	methenyltetrahydrofolate cyclohydrolase [Anabaena sp. PCC 7108].	49.47	285	138	2	2	286	5	283	2e-87	275
rs:XP_012454446	PREDICTED: bifunctional protein FolD 4, chloroplastic-like isoform X1 [Gossypium raimondii].	48.46	293	145	2	2	292	70	358	2e-87	277
rs:WP_002223192	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Neisseria].	50.52	289	133	2	1	289	1	279	2e-87	275
sp:FOLD_POLNS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.32	292	137	3	1	292	1	281	2e-87	275
rs:WP_033945117	methenyltetrahydrofolate cyclohydrolase [Pseudomonas aeruginosa].	48.97	290	138	2	1	290	1	280	2e-87	275
rs:WP_027109604	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium NC2008].	51.41	284	127	3	3	286	2	274	2e-87	274
rs:WP_037406853	methenyltetrahydrofolate cyclohydrolase [Snodgrassella alvi].	49.31	290	137	3	1	290	1	280	2e-87	275
rs:WP_026377260	methenyltetrahydrofolate cyclohydrolase [Aestuariibacter salexigens].	49.83	291	136	3	1	291	1	281	2e-87	275
rs:WP_004718865	methenyltetrahydrofolate cyclohydrolase [Yersinia ruckeri].	50.17	291	135	3	1	291	1	281	2e-87	275
tr:J0TQ33_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.83	288	146	2	5	292	8	285	2e-87	275
rs:WP_019674809	methenyltetrahydrofolate cyclohydrolase [Rheinheimera perlucida].	50.34	290	134	3	1	290	1	280	2e-87	275
rs:XP_004742279	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Mustela putorius furo].	50.51	295	139	3	3	291	37	330	2e-87	277
rs:WP_021985625	bifunctional protein FolD [Clostridium sp. CAG:127].	49.83	289	134	3	3	291	2	279	2e-87	274
rs:WP_013352834	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus subtilis group].	47.78	293	142	4	1	293	1	282	2e-87	275
tr:A0A091R4M5_MERNU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFQ34431.1}; Flags: Fragment;	50.51	295	138	4	3	291	2	294	2e-87	275
rs:WP_045168029	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella intermedia].	46.94	294	155	1	1	294	1	293	2e-87	275
rs:WP_018660625	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus acidiproducens].	50.17	291	134	4	1	291	1	280	2e-87	275
tr:A0A091SSP4_9AVES	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFQ61742.1}; Flags: Fragment;	50.67	298	140	3	3	294	4	300	2e-87	275
rs:XP_009482121	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Pelecanus crispus].	50.67	298	140	3	3	294	3	299	2e-87	275
tr:Q2KTB0_9PSED	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.66	290	136	2	1	290	1	280	2e-87	275
rs:WP_000525738	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.83	288	146	2	5	292	10	287	3e-87	275
rs:WP_027117373	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium YSB2008].	51.22	287	130	3	3	289	2	278	3e-87	275
rs:WP_017472278	hypothetical protein [Amphibacillus jilinensis].	47.40	289	141	3	1	289	1	278	3e-87	274
rs:WP_008327011	5,10-methylene-tetrahydrofolate dehydrogenase [Herbaspirillum sp. GW103].	49.32	292	137	3	1	292	1	281	3e-87	274
tr:A0A091QPN5_9GRUI	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFQ28591.1}; Flags: Fragment;	51.34	298	138	3	3	294	4	300	3e-87	275
rs:WP_013065317	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella ruminicola].	50.17	291	144	1	4	294	2	291	3e-87	275
rs:WP_021141875	methylenetetrahydrofolate dehydrogenase [Streptococcus equinus].	50.17	291	135	3	3	293	2	282	3e-87	274
rs:WP_027436429	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium AB2028].	50.00	284	131	3	3	286	2	274	3e-87	274
rs:WP_009850110	methenyltetrahydrofolate cyclohydrolase [Mariprofundus ferrooxydans].	47.60	292	143	2	2	293	5	286	3e-87	275
rs:XP_009988029	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Tauraco erythrolophus].	50.00	302	141	4	3	295	3	303	3e-87	275
rs:WP_028605228	methenyltetrahydrofolate cyclohydrolase [Ottowia thiooxydans].	49.49	293	137	4	1	293	1	282	3e-87	274
rs:WP_024998885	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella falsenii].	46.60	294	156	1	1	294	1	293	3e-87	275
rs:WP_014779875	methenyltetrahydrofolate cyclohydrolase [Thiocystis violascens].	49.66	290	136	2	1	290	1	280	3e-87	275
rs:XP_006735367	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Leptonychotes weddellii].	51.19	295	137	3	3	291	37	330	3e-87	276
rs:WP_018294190	methenyltetrahydrofolate cyclohydrolase [Mariprofundus ferrooxydans].	47.26	292	144	2	2	293	5	286	3e-87	275
rs:XP_010192092	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Mesitornis unicolor].	51.34	298	138	3	3	294	3	299	3e-87	275
rs:WP_035509040	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Halobacillus].	49.14	291	136	3	1	291	1	279	3e-87	274
rs:WP_010328289	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus vallismortis].	48.12	293	141	4	1	293	1	282	3e-87	274
rs:WP_018450993	5,10-methylene-tetrahydrofolate dehydrogenase [Leptotrichia shahii].	48.28	290	138	3	5	293	3	281	3e-87	274
rs:WP_044200523	5,10-methylene-tetrahydrofolate cyclohydrolase [Flammeovirga sp. OC4].	45.49	288	157	0	4	291	2	289	3e-87	275
rs:WP_006738844	tetrahydrofolate dehydrogenase [Streptococcus urinalis].	49.31	290	137	2	4	293	3	282	3e-87	274
rs:WP_015246442	5,10-methylene-tetrahydrofolate dehydrogenase [Singulisphaera acidiphila].	48.46	293	145	1	1	293	1	287	3e-87	275
rs:WP_038243793	methenyltetrahydrofolate cyclohydrolase [Yersinia ruckeri].	50.17	291	135	3	1	291	1	281	3e-87	274
rs:WP_023536010	tetrahydrofolate dehydrogenase [Pseudomonas putida].	48.62	290	139	2	1	290	1	280	3e-87	274
rs:WP_035506479	methenyltetrahydrofolate cyclohydrolase [Burkholderia sp. MP-1].	49.32	292	137	4	1	292	1	281	3e-87	274
rs:WP_002936826	5,10-methylene-tetrahydrofolate dehydrogenase [Thauera sp. 27].	49.66	292	140	3	1	292	1	285	3e-87	274
rs:WP_026700252	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus aidingensis].	48.80	291	137	3	1	291	1	279	3e-87	274
rs:WP_008449920	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella amnii].	46.26	294	157	1	1	294	1	293	3e-87	275
rs:XP_009620377	PREDICTED: bifunctional protein FolD 4, chloroplastic [Nicotiana tomentosiformis].	49.15	293	143	2	2	292	77	365	3e-87	277
rs:WP_015133394	5,10-methylene-tetrahydrofolate dehydrogenase [Leptolyngbya sp. PCC 7376].	48.59	284	141	2	3	286	2	280	3e-87	274
sp:FOLD_AMOA5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.58	294	156	2	3	294	2	293	3e-87	275
rs:WP_024999997	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella aurantiaca].	45.92	294	158	1	1	294	1	293	3e-87	275
rs:WP_007543640	5,10-methylene-tetrahydrofolate dehydrogenase [Haloferax larsenii].	50.69	288	140	2	5	292	4	289	3e-87	275
rs:WP_017661986	hypothetical protein [Geitlerinema sp. PCC 7105].	48.63	292	144	2	2	293	3	288	3e-87	274
rs:WP_018935777	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio sp. ALJ24].	50.35	288	133	2	1	288	1	278	3e-87	274
rs:WP_024122012	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillaceae].	48.12	293	141	4	1	293	1	282	3e-87	274
tr:A0A0B7IS03_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.31	288	136	2	1	288	20	297	3e-87	275
rs:WP_021323812	5,10-methylene-tetrahydrofolate dehydrogenase [Photorhabdus temperata].	50.17	291	135	2	1	291	1	281	3e-87	275
tr:A0A091I8H3_CALAN	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFP03695.1}; Flags: Fragment;	51.01	298	139	3	3	294	4	300	3e-87	275
rs:WP_028560015	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus pinihumi].	50.52	291	133	4	1	291	1	280	3e-87	274
rs:WP_018525287	hypothetical protein [Spirochaeta alkalica].	47.24	290	152	1	1	290	1	289	3e-87	275
rs:WP_015384072	bifunctional protein FolD [Bacillus subtilis].	48.12	293	141	4	1	293	1	282	3e-87	274
rs:WP_038171506	methenyltetrahydrofolate cyclohydrolase [Verrucomicrobium sp. BvORR106].	50.68	292	140	4	4	293	2	291	3e-87	275
rs:WP_045798140	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus equinus].	50.17	291	135	3	3	293	2	282	4e-87	274
rs:WP_014334429	tetrahydrofolate dehydrogenase [Streptococcus infantarius].	49.83	291	136	3	3	293	2	282	4e-87	274
rs:WP_038057844	methenyltetrahydrofolate cyclohydrolase [Thermodesulfobacterium hydrogeniphilum].	49.48	291	145	2	1	290	1	290	4e-87	275
rs:WP_003632130	methenyltetrahydrofolate cyclohydrolase [Legionella longbeachae].	50.70	286	131	2	1	286	1	276	4e-87	274
tr:H2ZVQ9_LATCH	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLACP00000001480}; Flags: Fragment;	50.34	294	139	3	3	290	27	319	4e-87	275
rs:WP_008868921	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfonatronospira thiodismutans].	49.14	291	136	4	1	291	1	279	4e-87	274
tr:A0A093QN91_9PASS	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFW85447.1}; Flags: Fragment;	51.01	298	139	3	3	294	4	300	4e-87	275
rs:WP_044976196	5,10-methylene-tetrahydrofolate cyclohydrolase [Ruminococcus sp. HUN007].	51.22	287	129	4	3	289	2	277	4e-87	274
rs:XP_004072405	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Oryzias latipes].	50.00	300	142	4	3	295	30	328	4e-87	276
rs:WP_023938592	MULTISPECIES: methylenetetrahydrofolate dehydrogenase [Porphyromonas].	46.71	289	154	0	5	293	11	299	4e-87	275
rs:WP_018140294	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio].	50.35	288	133	2	1	288	1	278	4e-87	274
rs:WP_019786387	tetrahydrofolate dehydrogenase [Streptococcus sobrinus].	48.81	293	140	2	1	293	1	283	4e-87	274
rs:WP_027177704	methenyltetrahydrofolate cyclohydrolase [Desulfovibrio bastinii].	50.00	286	136	2	5	290	3	281	4e-87	274
sp:FOLD_NEIM0	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.52	289	133	2	1	289	1	279	4e-87	274
rs:WP_039697272	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus equinus].	49.83	291	136	3	3	293	2	282	4e-87	274
tr:B1SD49_9STRE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.83	291	136	3	3	293	19	299	4e-87	275
rs:XP_010895662	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Esox lucius].	51.53	295	136	4	3	291	30	323	4e-87	276
tr:H8H4W6_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.49	288	147	2	5	292	8	285	4e-87	274
rs:WP_010789179	bifunctional 5,10-methylene-tetrahydrofolate [Bacillus atrophaeus].	48.12	293	141	4	1	293	1	282	4e-87	274
rs:WP_010445786	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fuscovaginae].	48.97	290	138	2	1	290	1	280	4e-87	274
rs:WP_017848149	methenyltetrahydrofolate cyclohydrolase [Pseudomonas veronii].	48.97	290	138	2	1	290	1	280	4e-87	274
rs:WP_036946314	hypothetical protein [Pseudobacteroides cellulosolvens].	50.34	290	133	3	1	290	1	279	4e-87	274
rs:WP_025457474	methenyltetrahydrofolate cyclohydrolase [Neisseria polysaccharea].	50.17	289	134	2	1	289	1	279	4e-87	274
rs:WP_036185580	methenyltetrahydrofolate cyclohydrolase [Marinobacterium sp. AK27].	51.21	289	131	3	2	290	3	281	4e-87	274
rs:WP_022312814	bifunctional protein FolD [Clostridium sp. CAG:91].	51.76	284	126	3	3	286	2	274	4e-87	274
rs:WP_025391372	5,10-methylene-tetrahydrofolate cyclohydrolase [Desulfurella acetivorans].	48.96	288	135	3	5	292	3	278	4e-87	274
rs:WP_029407264	methenyltetrahydrofolate cyclohydrolase [Thiomicrospira sp. Milos-T2].	47.40	289	142	2	1	289	1	279	4e-87	274
rs:WP_035890466	methenyltetrahydrofolate cyclohydrolase [Legionella norrlandica].	47.42	291	143	2	1	291	1	281	4e-87	274
rs:WP_043185889	methenyltetrahydrofolate cyclohydrolase [Pseudomonas rhizosphaerae].	49.31	290	137	2	1	290	1	280	4e-87	274
rs:WP_029522459	5,10-methylene-tetrahydrofolate cyclohydrolase [Persephonella sp. KM09-Lau-8].	47.96	294	143	3	1	293	1	285	4e-87	274
rs:WP_013321825	methenyltetrahydrofolate cyclohydrolase [Cyanothece sp. PCC 7822].	47.60	292	147	2	2	293	5	290	4e-87	274
rs:XP_008288062	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Stegastes partitus].	50.67	300	140	5	3	295	30	328	4e-87	276
rs:WP_009433597	5,10-methylene-tetrahydrofolate dehydrogenase [Porphyromonas sp. oral taxon 279].	45.33	289	158	0	4	292	7	295	4e-87	274
rs:WP_045159016	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	48.62	290	139	2	1	290	1	280	4e-87	274
sp:FOLD_GEOUR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.13	289	136	3	3	291	2	279	4e-87	274
rs:WP_015226615	5,10-methylene-tetrahydrofolate dehydrogenase [Halothece sp. PCC 7418].	48.64	294	143	3	3	294	6	293	4e-87	274
gp:AK223041_1	methylene tetrahydrofolate dehydrogenase 2 precursor variant [Homo sapiens]	50.85	295	138	3	3	291	31	324	4e-87	276
gp:AK222826_1	methylene tetrahydrofolate dehydrogenase 2 precursor variant [Homo sapiens]	50.85	295	138	3	3	291	31	324	4e-87	276
rs:WP_008158220	5,10-methylene-tetrahydrofolate dehydrogenase [Achromobacter arsenitoxydans].	49.66	292	136	3	1	292	1	281	4e-87	274
rs:WP_035559720	5,10-methylene-tetrahydrofolate cyclohydrolase [Hymenobacter sp. IS2118].	46.26	294	158	0	2	295	6	299	4e-87	275
rs:WP_019787301	tetrahydrofolate dehydrogenase [Streptococcus sobrinus].	48.81	293	140	2	1	293	1	283	5e-87	274
rs:WP_029922861	methenyltetrahydrofolate cyclohydrolase [Nevskia soli].	49.31	290	137	2	1	290	1	280	5e-87	274
rs:WP_019880977	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Methylophilus].	48.96	288	137	2	1	288	1	278	5e-87	274
rs:WP_018977547	5,10-methylene-tetrahydrofolate dehydrogenase [Saccharibacillus kuerlensis].	49.83	291	135	4	2	292	3	282	5e-87	274
rs:XP_008438073	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X2 [Cucumis melo].	48.81	293	144	2	2	292	34	322	5e-87	275
rs:WP_038660353	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	48.97	290	138	2	1	290	1	280	5e-87	274
rs:WP_025003234	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella dentasini].	45.58	294	159	1	1	294	1	293	5e-87	274
tr:X0ZUM8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_C01772 {ECO:0000313|EMBL:GAG73129.1};	48.68	304	139	2	1	291	1	300	5e-87	275
rs:WP_036648219	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. YR343].	49.83	291	136	3	1	291	1	281	5e-87	274
rs:WP_046214946	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus wulumuqiensis].	48.97	292	138	3	1	292	1	281	5e-87	274
rs:WP_014574295	methenyltetrahydrofolate cyclohydrolase [Neisseria meningitidis].	50.17	289	134	2	1	289	1	279	5e-87	274
rs:WP_019784989	tetrahydrofolate dehydrogenase [Streptococcus sobrinus].	49.15	293	139	2	1	293	1	283	5e-87	274
rs:WP_000525741	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.49	288	147	2	5	292	10	287	5e-87	274
rs:WP_046231949	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus algorifonticola].	48.97	292	138	3	1	292	1	281	5e-87	274
rs:WP_027452907	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella bryantii].	48.11	291	150	1	4	294	2	291	5e-87	274
rs:WP_003749140	methenyltetrahydrofolate cyclohydrolase [Neisseria mucosa].	50.86	291	129	3	1	289	1	279	5e-87	274
rs:WP_019639056	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus fonticola].	50.17	291	134	3	1	291	1	280	5e-87	274
rs:WP_034336775	methenyltetrahydrofolate cyclohydrolase [Herbaspirillum sp. B39].	49.32	292	137	3	1	292	1	281	5e-87	273
rs:WP_006283380	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella bryantii].	48.11	291	150	1	4	294	2	291	5e-87	274
rs:WP_022688385	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas-like bacterium B12].	50.86	291	137	2	1	291	1	285	5e-87	274
rs:WP_038412800	methenyltetrahydrofolate cyclohydrolase [Pseudomonas cremoricolorata].	48.45	291	140	2	1	291	1	281	5e-87	274
rs:WP_012676915	5,10-methylene-tetrahydrofolate dehydrogenase [Persephonella marina].	49.65	288	135	3	5	291	4	282	5e-87	274
rs:WP_016939002	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus siamensis].	47.78	293	142	4	1	293	1	282	5e-87	273
rs:WP_028303744	methenyltetrahydrofolate cyclohydrolase [Oceanospirillum maris].	48.97	290	138	3	1	290	1	280	5e-87	274
rs:WP_046850854	methenyltetrahydrofolate cyclohydrolase [Nitrosomonas communis].	49.32	292	137	3	1	292	1	281	5e-87	274
rs:WP_028223248	methenyltetrahydrofolate cyclohydrolase [Burkholderia oxyphila].	52.92	291	126	3	1	291	1	280	5e-87	274
rs:WP_024630992	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus].	50.00	292	135	3	1	292	1	281	5e-87	274
rs:WP_042126242	methenyltetrahydrofolate cyclohydrolase [Pseudomonas japonica].	48.45	291	140	2	1	291	1	281	5e-87	273
rs:XP_002613716	hypothetical protein BRAFLDRAFT_62006 [Branchiostoma floridae].	52.80	286	128	3	11	290	1	285	5e-87	274
rs:WP_022451095	bifunctional protein FolD [Clostridium sp. CAG:269].	48.60	286	136	4	5	290	2	276	5e-87	274
rs:WP_034741876	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus wakoensis].	50.17	291	133	3	1	291	1	279	5e-87	273
rs:WP_015192915	5,10-methylene-tetrahydrofolate dehydrogenase [Stanieria cyanosphaera].	47.26	292	148	2	2	293	5	290	5e-87	274
rs:XP_008438072	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X1 [Cucumis melo].	48.81	293	144	2	2	292	71	359	5e-87	276
rs:XP_005495934	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Zonotrichia albicollis].	50.67	298	140	3	3	294	51	347	5e-87	276
rs:WP_038536054	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. X1(2014)].	48.81	293	139	4	1	293	1	282	5e-87	273
rs:WP_023043791	methenyltetrahydrofolate cyclohydrolase [Photorhabdus temperata].	49.83	291	136	2	1	291	1	281	5e-87	274
rs:WP_020167067	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Methylotenera].	48.63	292	140	2	1	292	1	282	5e-87	274
tr:A0A091M7M5_CARIC	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFP67793.1}; Flags: Fragment;	50.67	298	140	3	3	294	4	300	5e-87	274
rs:WP_024344248	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus equinus].	50.86	291	133	3	3	293	2	282	5e-87	273
rs:WP_012971225	methenyltetrahydrofolate cyclohydrolase [Allochromatium vinosum].	49.31	290	137	2	1	290	1	280	6e-87	274
rs:WP_002260804	tetrahydrofolate dehydrogenase [Neisseria meningitidis].	50.52	289	133	2	1	289	1	279	6e-87	273
rs:XP_009795120	PREDICTED: bifunctional protein FolD 4, chloroplastic-like [Nicotiana sylvestris].	49.32	292	142	2	2	291	77	364	6e-87	276
rs:WP_018124377	hypothetical protein [Desulfovibrio oxyclinae].	49.83	289	134	3	5	293	3	280	6e-87	273
rs:WP_007890770	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. GM01].	49.48	291	137	3	1	291	1	281	6e-87	274
rs:WP_001133663	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	46.88	288	143	2	5	292	8	285	6e-87	274
rs:XP_006009408	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Latimeria chalumnae].	50.34	294	139	3	3	290	45	337	6e-87	275
rs:XP_005429314	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Geospiza fortis].	50.67	298	140	3	3	294	50	346	6e-87	276
rs:WP_022295741	bifunctional protein FolD [Firmicutes bacterium CAG:272].	51.03	290	128	4	3	292	2	277	6e-87	273
tr:B5X281_SALSA	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:ACI33412.1};	52.38	294	133	4	3	290	30	322	6e-87	275
rs:WP_038338832	5,10-methylene-tetrahydrofolate cyclohydrolase [endosymbiont of Bathymodiolus sp.].	50.35	286	128	3	5	290	4	275	6e-87	273
sp:FOLD_CHLT3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.42	284	153	1	5	286	3	286	6e-87	274
rs:WP_005996295	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio fructosivorans].	49.49	297	140	2	5	297	3	293	6e-87	274
rs:WP_022423508	bifunctional protein FolD [Clostridium sp. CAG:440].	48.26	288	138	3	3	290	2	278	6e-87	273
rs:XP_004437203	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Ceratotherium simum simum].	50.84	299	140	3	3	295	37	334	6e-87	276
rs:WP_006473972	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [sulfur-oxidizing symbionts].	48.97	290	138	3	1	290	1	280	7e-87	273
rs:WP_028844497	5,10-methylene-tetrahydrofolate cyclohydrolase [Thermodesulfovibrio thiophilus].	49.13	287	135	4	4	290	3	278	7e-87	273
rs:WP_028521038	5,10-methylene-tetrahydrofolate cyclohydrolase [Ruminococcus flavefaciens].	48.97	290	138	2	3	292	2	281	7e-87	273
rs:WP_042142284	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas sp. '520P1 No. 412'].	49.48	291	137	3	1	291	1	281	7e-87	273
rs:XP_007062923	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Chelonia mydas].	50.34	298	141	3	3	294	3	299	7e-87	274
rs:WP_042413642	5,10-methylene-tetrahydrofolate cyclohydrolase [Geomicrobium sp. JCM 19038].	47.77	291	140	3	1	291	1	279	7e-87	273
tr:D8LW74_BLAHO	SubName: Full=Singapore isolate B (sub-type 7) whole genome shotgun sequence assembly, scaffold_0 {ECO:0000313|EMBL:CBK20063.2};	47.16	299	152	2	1	297	1	295	7e-87	274
rs:WP_027966768	methenyltetrahydrofolate cyclohydrolase [Halomonas halocynthiae].	48.28	290	140	2	1	290	1	280	7e-87	273
rs:WP_018751505	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus sanguinis].	49.83	291	135	3	1	291	1	280	7e-87	273
rs:WP_029908219	methenyltetrahydrofolate cyclohydrolase [Hydrogenovibrio marinus].	49.48	289	136	2	1	289	1	279	7e-87	273
rs:WP_023275624	hypothetical protein [Mucispirillum schaedleri].	47.92	288	139	2	3	290	2	278	7e-87	273
sp:FOLD_CAMC1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	52.41	290	127	4	4	293	2	280	7e-87	273
rs:WP_019909674	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus sp. HW567].	49.83	291	135	3	1	291	1	280	7e-87	273
rs:WP_018576924	methenyltetrahydrofolate cyclohydrolase [Legionella shakespearei].	48.11	291	141	2	1	291	1	281	7e-87	273
rs:WP_013688017	5,10-methylene-tetrahydrofolate dehydrogenase [Fluviicola taffensis].	46.32	285	153	0	4	288	2	286	7e-87	273
tr:G2DH03_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.97	290	138	3	1	290	6	285	7e-87	273
rs:WP_027849659	methenyltetrahydrofolate cyclohydrolase [Marinospirillum minutulum].	47.44	293	144	2	1	293	1	283	7e-87	273
rs:WP_000137496	tetrahydrofolate dehydrogenase [Streptococcus agalactiae].	48.97	290	138	3	4	293	3	282	7e-87	273
rs:WP_037022587	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. 20_BN].	48.62	290	139	2	1	290	1	280	7e-87	273
rs:XP_004134331	PREDICTED: bifunctional protein FolD 4, chloroplastic [Cucumis sativus].	48.81	293	144	2	2	292	71	359	7e-87	276
rs:WP_028904303	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella sp. P6B4].	50.17	291	144	1	4	294	2	291	7e-87	273
rs:WP_026685985	methenyltetrahydrofolate cyclohydrolase [Azovibrio restrictus].	48.29	292	143	3	1	292	1	284	7e-87	273
rs:WP_006192929	5,10-methylene-tetrahydrofolate dehydrogenase [Selenomonas sputigena].	49.49	295	137	3	1	293	1	285	7e-87	273
rs:WP_003708842	methenyltetrahydrofolate cyclohydrolase [Neisseria lactamica].	50.52	289	133	2	1	289	1	279	8e-87	273
tr:J0J9A8_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.49	288	147	2	5	292	8	285	8e-87	273
rs:WP_019768917	tetrahydrofolate dehydrogenase [Streptococcus sobrinus].	48.81	293	140	2	1	293	1	283	8e-87	273
rs:WP_009984245	5,10-methylene-tetrahydrofolate dehydrogenase [Ruminococcus flavefaciens].	49.31	290	137	3	3	292	2	281	8e-87	273
rs:WP_042399551	5,10-methylene-tetrahydrofolate cyclohydrolase [Geomicrobium sp. JCM 19037].	49.31	290	136	3	1	290	1	279	8e-87	273
tr:A0A091E9E9_CORBR	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFO54673.1}; Flags: Fragment;	50.34	298	141	3	3	294	4	300	8e-87	274
rs:WP_044415736	5,10-methylene-tetrahydrofolate cyclohydrolase [Arcobacter anaerophilus].	49.30	286	135	2	5	290	3	278	8e-87	273
rs:WP_000137497	tetrahydrofolate dehydrogenase [Streptococcus agalactiae].	48.97	290	138	3	4	293	3	282	8e-87	273
rs:WP_035719750	5,10-methylene-tetrahydrofolate cyclohydrolase [Francisella sp. W12-1067].	47.92	288	138	3	5	291	3	279	8e-87	273
rs:WP_044221918	5,10-methylene-tetrahydrofolate cyclohydrolase [Flammeovirga pacifica].	46.53	288	154	0	4	291	2	289	8e-87	273
rs:WP_035647803	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium NK4A179].	50.34	290	133	3	1	290	1	279	8e-87	273
rs:WP_000525735	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.49	288	147	2	5	292	10	287	8e-87	273
rs:WP_019556648	methenyltetrahydrofolate cyclohydrolase [Thiomicrospira arctica].	47.75	289	141	2	1	289	1	279	8e-87	273
rs:WP_028610443	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus harenae].	48.97	292	138	3	1	292	1	281	8e-87	273
rs:WP_019776699	tetrahydrofolate dehydrogenase [Streptococcus sobrinus].	48.81	293	140	2	1	293	1	283	8e-87	273
rs:WP_022299355	bifunctional protein FolD [Clostridium sp. CAG:964].	51.21	289	129	4	3	290	2	279	8e-87	273
rs:WP_022410620	bifunctional protein FolD [Ruminococcus sp. CAG:330].	50.00	288	134	3	3	290	2	279	8e-87	273
rs:XP_011957515	PREDICTED: LOW QUALITY PROTEIN: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like isoform X1 [Ovis aries].	52.20	295	134	3	3	291	37	330	8e-87	275
rs:WP_020599752	5,10-methylene-tetrahydrofolate dehydrogenase [Spirosoma panaciterrae].	44.67	291	161	0	4	294	2	292	8e-87	273
rs:WP_014888309	methenyltetrahydrofolate cyclohydrolase [secondary endosymbiont of Ctenarytaina eucalypti].	50.34	290	134	3	1	290	1	280	8e-87	273
tr:A0A091WCL0_OPIHO	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFR12860.1}; Flags: Fragment;	51.01	298	139	3	3	294	4	300	8e-87	274
rs:WP_022723124	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodopseudomonas sp. B29].	48.97	290	143	2	1	290	1	285	8e-87	273
rs:WP_006836876	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus sp. SG-1].	47.78	293	142	4	1	293	1	282	8e-87	273
rs:WP_024862046	5,10-methylene-tetrahydrofolate cyclohydrolase [Ruminococcus flavefaciens].	48.28	290	140	2	3	292	2	281	8e-87	273
rs:WP_019679498	5,10-methylene-tetrahydrofolate dehydrogenase [Ruminococcus flavefaciens].	48.62	290	139	2	3	292	2	281	9e-87	273
rs:WP_036887656	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas crevioricanis].	46.71	289	154	0	5	293	11	299	9e-87	273
sp:FOLD_SHEDO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.62	290	139	3	1	290	1	280	9e-87	273
tr:A0A091PB02_LEPDC	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFQ04556.1}; Flags: Fragment;	51.01	298	139	3	3	294	4	300	9e-87	273
rs:XP_009980735	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Tauraco erythrolophus].	51.34	298	138	3	3	294	3	299	9e-87	273
rs:WP_018925421	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	48.28	290	140	2	1	290	1	280	9e-87	273
rs:WP_008048844	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. GM74].	47.93	290	141	2	1	290	1	280	9e-87	273
rs:WP_027267006	methenyltetrahydrofolate cyclohydrolase [Legionella pneumophila].	46.74	291	145	2	1	291	1	281	9e-87	273
sp:FOLD_LEGPC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.74	291	145	2	1	291	1	281	9e-87	273
tr:A0A0C4WMR6_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.42	291	143	2	1	291	1	281	9e-87	273
rs:WP_038472189	methenyltetrahydrofolate cyclohydrolase [Acidithiobacillus caldus].	48.45	291	140	2	1	291	1	281	9e-87	273
rs:WP_010564903	methenyltetrahydrofolate cyclohydrolase [Pseudomonas extremaustralis].	48.97	290	138	2	1	290	1	280	1e-86	273
tr:A0A087R264_APTFO	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFM07568.1}; Flags: Fragment;	50.67	298	140	3	3	294	4	300	1e-86	273
rs:WP_014397810	5,10-methylene-tetrahydrofolate dehydrogenase [Corallococcus coralloides].	48.81	293	139	3	1	293	1	282	1e-86	273
rs:WP_018259245	5,10-methylene-tetrahydrofolate dehydrogenase [Halomicrobium katesii].	48.79	289	146	2	4	292	3	289	1e-86	273
rs:WP_019714928	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus subtilis].	47.78	293	142	4	1	293	1	282	1e-86	273
rs:WP_015421211	methenyltetrahydrofolate cyclohydrolase [beta proteobacterium CB].	48.47	295	141	3	1	295	1	284	1e-86	273
rs:WP_002224177	methenyltetrahydrofolate cyclohydrolase [Neisseria meningitidis].	50.52	289	133	2	1	289	1	279	1e-86	273
rs:WP_018051914	hypothetical protein [SAR324 cluster bacterium SCGC AB-629-O05].	49.31	288	143	2	3	290	2	286	1e-86	273
rs:WP_028573888	methenyltetrahydrofolate cyclohydrolase [Desulfonatronovibrio hydrogenovorans].	49.13	287	135	2	5	291	3	278	1e-86	273
rs:WP_008220350	methenyltetrahydrofolate cyclohydrolase [Rheinheimera nanhaiensis].	50.34	290	134	3	1	290	1	280	1e-86	273
rs:WP_004277769	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter upsaliensis].	50.69	290	130	4	5	293	3	280	1e-86	273
rs:WP_004368194	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella oralis].	48.11	291	150	1	4	294	2	291	1e-86	273
rs:WP_017129552	methenyltetrahydrofolate cyclohydrolase [Pseudomonas gingeri].	48.28	290	140	2	1	290	1	280	1e-86	273
rs:WP_018052168	hypothetical protein [Marinimicrobia bacterium SCGC AB-629-J13].	46.53	288	152	2	4	291	3	288	1e-86	273
sp:FOLD_AZOVD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.77	291	142	2	1	291	1	281	1e-86	273
rs:WP_028381914	methenyltetrahydrofolate cyclohydrolase [Legionella cherrii].	50.87	289	132	2	1	289	1	279	1e-86	273
tr:F9ZR57_ACICS	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.45	291	140	2	1	291	12	292	1e-86	273
tr:A0A060XIB1_ONCMY	SubName: Full=Oncorhynchus mykiss genomic scaffold, scaffold_928 {ECO:0000313|EMBL:CDQ77054.1};	51.86	295	135	4	3	291	30	323	1e-86	275
rs:WP_015744396	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Methylomirabilis oxyfera].	48.97	292	137	4	1	291	1	281	1e-86	273
tr:A0A093CMK2_TAUER	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFV14179.1}; Flags: Fragment;	51.34	298	138	3	3	294	4	300	1e-86	273
rs:WP_016670874	tetrahydrofolate dehydrogenase [Neisseria meningitidis].	50.52	289	133	2	1	289	1	279	1e-86	273
tr:X0ZNH7_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_C00365 {ECO:0000313|EMBL:GAG71315.1};	45.51	301	147	2	3	290	5	301	1e-86	273
rs:WP_036614369	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. FSL H7-689].	50.68	292	133	4	1	292	1	281	1e-86	273
rs:WP_017906647	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fuscovaginae].	48.62	290	139	2	1	290	1	280	1e-86	273
rs:WP_017435213	5,10-methylene-tetrahydrofolate dehydrogenase [Geobacillus caldoxylosilyticus].	49.66	294	137	4	1	294	1	283	1e-86	273
rs:WP_015335977	methylenetetrahydrofolate dehydrogenase [Desulfovibrio hydrothermalis].	47.59	290	145	2	4	293	2	284	1e-86	273
rs:WP_041961648	methenyltetrahydrofolate cyclohydrolase [Neisseria elongata].	49.32	292	134	3	1	290	1	280	1e-86	273
rs:WP_040197736	5,10-methylene-tetrahydrofolate cyclohydrolase [Candidatus Soleaferrea massiliensis].	51.89	291	130	2	1	291	1	281	1e-86	273
gpu:CP009503_656	Methylenetetrahydrofolate dehydrogenase (NADP+) [Methanosarcina sp. WWM596]	48.45	291	139	3	3	293	8	287	1e-86	273
rs:WP_018870331	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio sp. ALgr3].	50.00	288	134	2	1	288	1	278	1e-86	273
rs:WP_027492524	methenyltetrahydrofolate cyclohydrolase [Rhodanobacter sp. OR444].	51.38	290	131	2	1	290	1	280	1e-86	273
rs:WP_014950149	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Alteromonas].	49.48	291	137	2	1	291	1	281	1e-86	273
rs:WP_014709892	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella intermedia].	46.60	294	156	1	1	294	1	293	1e-86	273
tr:J2VKY9_9ENTR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.83	291	136	3	1	291	31	311	1e-86	274
rs:XP_008495631	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Calypte anna].	51.01	298	139	3	3	294	49	345	1e-86	275
rs:XP_010013712	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Nestor notabilis].	50.67	298	140	3	3	294	3	299	1e-86	273
rs:WP_003332485	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus azotoformans].	48.81	293	139	4	1	293	1	282	1e-86	273
rs:WP_036657544	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus wynnii].	48.80	291	138	3	1	291	1	280	1e-86	273
rs:WP_022473584	bifunctional protein FolD [Sutterella sp. CAG:521].	50.86	291	129	4	1	291	1	277	1e-86	273
rs:WP_026788492	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Planktothrix].	47.52	282	142	2	5	286	4	279	1e-86	273
rs:WP_015719659	5,10-methylene-tetrahydrofolate dehydrogenase [Geobacter sp. M18].	48.45	291	139	3	3	293	2	281	1e-86	273
rs:WP_038246991	methenyltetrahydrofolate cyclohydrolase [Zetaproteobacteria bacterium TAG-1].	48.11	291	141	2	3	293	2	282	1e-86	273
rs:WP_044932728	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. AC2005].	50.35	286	133	2	4	289	2	278	1e-86	273
rs:WP_009403826	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas putida].	48.45	291	140	2	1	291	1	281	1e-86	273
rs:WP_009294633	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter sp. 10_1_50].	52.41	290	127	4	4	293	2	280	1e-86	273
rs:WP_027220713	bifunctional protein FolD [Legionella pneumophila].	46.74	291	145	2	1	291	1	281	1e-86	273
rs:WP_015447649	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Rhodanobacter].	50.51	295	136	2	1	295	1	285	1e-86	273
rs:WP_022474222	bifunctional protein FolD [Ruminococcus sp. CAG:353].	51.90	289	128	4	3	291	2	279	1e-86	273
rs:WP_036113013	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Luteibacter].	49.66	290	136	2	1	290	1	280	1e-86	273
rs:WP_039785892	methenyltetrahydrofolate cyclohydrolase [Herbaspirillum huttiense].	48.97	292	138	3	1	292	1	281	1e-86	272
rs:WP_006955112	methenyltetrahydrofolate cyclohydrolase [Idiomarina baltica].	48.61	288	138	2	1	288	1	278	1e-86	273
rs:WP_022088504	bifunctional protein FolD [Eubacterium sp. CAG:156].	52.26	287	126	3	4	290	2	277	1e-86	272
rs:WP_014841472	bifunctional protein FolD [Legionella pneumophila].	46.74	291	145	2	1	291	1	281	1e-86	273
rs:WP_034840690	methenyltetrahydrofolate cyclohydrolase [Endozoicomonas numazuensis].	49.66	290	136	2	1	290	1	280	1e-86	273
rs:WP_015094300	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. UW4].	47.93	290	141	2	1	290	1	280	1e-86	273
rs:XP_011836151	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Mandrillus leucophaeus].	51.53	295	136	3	3	291	219	512	1e-86	280
rs:WP_014843759	bifunctional protein FolD [Legionella pneumophila].	46.74	291	145	2	1	291	1	281	1e-86	273
rs:WP_009049852	methenyltetrahydrofolate cyclohydrolase [Pseudomonas chlororaphis].	48.62	290	139	2	1	290	1	280	1e-86	273
rs:WP_021973122	bifunctional protein FolD [Eubacterium sp. CAG:180].	50.69	290	132	3	3	292	2	280	1e-86	273
sp:FOLD_STRA1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.97	290	138	3	4	293	3	282	1e-86	273
rs:WP_015644259	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.49	288	147	2	5	292	8	285	1e-86	273
rs:WP_007508359	methenyltetrahydrofolate cyclohydrolase [Rhodanobacter denitrificans].	50.51	295	136	2	1	295	1	285	1e-86	273
rs:WP_025657391	methenyltetrahydrofolate cyclohydrolase [Clostridiales bacterium VE202-21].	51.04	288	130	4	3	290	2	278	1e-86	272
tr:A0A093P0G3_PYGAD	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFW67680.1}; Flags: Fragment;	50.67	298	140	3	3	294	4	300	1e-86	273
rs:XP_010155566	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Eurypyga helias].	51.01	298	139	3	3	294	50	346	1e-86	275
rs:WP_045489729	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. StFLB209].	47.93	290	141	2	1	290	1	280	1e-86	273
rs:WP_019987299	5,10-methylene-tetrahydrofolate dehydrogenase [Rudanella lutea].	43.64	291	164	0	4	294	2	292	1e-86	273
tr:G3A4D5_9RALS	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.51	295	133	5	2	294	3	286	1e-86	273
rs:WP_000137501	bifunctional protein FolD [Streptococcus agalactiae].	48.97	290	138	3	4	293	3	282	1e-86	273
rs:WP_015350519	methylenetetrahydrofolate dehydrogenase [Myxococcus stipitatus].	47.60	292	149	3	3	293	2	290	1e-86	273
rs:WP_024955596	5,10-methylene-tetrahydrofolate cyclohydrolase [Sulfurospirillum arcachonense].	49.31	288	135	4	4	291	2	278	2e-86	272
tr:A0A091S4T2_NESNO	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFQ50370.1}; Flags: Fragment;	50.67	298	140	3	3	294	4	300	2e-86	273
tr:F8C7R5_MYXFH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.46	279	137	3	15	292	1	276	2e-86	272
rs:WP_045212179	methenyltetrahydrofolate cyclohydrolase [Desulfobulbus alkaliphilus].	47.90	286	138	2	5	290	3	277	2e-86	272
rs:WP_007129727	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus lactis].	51.38	290	130	4	2	291	3	281	2e-86	273
rs:XP_010080480	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Pterocles gutturalis].	50.34	298	141	3	3	294	3	299	2e-86	273
rs:XP_009959246	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Leptosomus discolor].	51.01	298	139	3	3	294	10	306	2e-86	273
rs:WP_037013646	methenyltetrahydrofolate cyclohydrolase [Pseudomonas lutea].	48.62	290	139	2	1	290	1	280	2e-86	272
rs:WP_018873415	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio sp. ALJ16].	50.35	288	133	2	1	288	1	278	2e-86	272
rs:WP_037591785	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus hongkongensis].	47.93	290	141	2	4	293	3	282	2e-86	272
rs:WP_036141554	methenyltetrahydrofolate cyclohydrolase [Luteibacter sp. 9135].	50.35	286	132	2	1	286	1	276	2e-86	273
rs:WP_026489828	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. XBB1001].	51.71	292	127	4	1	289	1	281	2e-86	272
rs:WP_008001570	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. GM49].	47.93	290	141	2	1	290	1	280	2e-86	272
rs:WP_027919617	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. URMO17WK12:I8].	47.77	291	142	2	1	291	1	281	2e-86	272
rs:WP_022365909	bifunctional protein FolD [Firmicutes bacterium CAG:341].	52.08	288	127	4	3	290	9	285	2e-86	273
rs:WP_041875485	methenyltetrahydrofolate cyclohydrolase [Marinimicrobia bacterium SCGC AAA257-N23].	46.39	291	155	1	3	293	4	293	2e-86	273
rs:WP_028403686	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. J13].	51.03	290	131	4	2	291	3	281	2e-86	272
tr:A0A0C9PQ37_LEGPN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.74	291	145	2	1	291	1	281	2e-86	272
rs:WP_036782056	5,10-methylene-tetrahydrofolate cyclohydrolase [Pontibacillus chungwhensis].	48.45	291	139	3	1	291	1	280	2e-86	272
tr:A0A093EI54_9AVES	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFV14216.1}; Flags: Fragment;	50.34	298	141	3	3	294	4	300	2e-86	273
tr:A0A091G8Y9_9AVES	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFO70662.1}; Flags: Fragment;	51.01	298	139	3	3	294	4	300	2e-86	273
rs:WP_028212660	methenyltetrahydrofolate cyclohydrolase [Burkholderia mimosarum].	52.58	291	127	3	1	291	1	280	2e-86	273
rs:WP_026509376	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. LC3010].	49.47	285	135	2	5	289	3	278	2e-86	272
tr:R0K936_ANAPL	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:EOB06322.1}; Flags: Fragment;	50.00	298	142	3	3	294	4	300	2e-86	273
rs:WP_018283625	methenyltetrahydrofolate cyclohydrolase [zeta proteobacterium SCGC AB-137-C09].	46.58	292	146	2	1	292	1	282	2e-86	272
rs:WP_018946862	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio].	50.00	288	134	2	1	288	1	278	2e-86	272
rs:WP_028237820	methenyltetrahydrofolate cyclohydrolase [Pseudomonas azotifigens].	48.97	290	138	2	1	290	1	280	2e-86	272
rs:XP_009277608	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Aptenodytes forsteri].	50.67	298	140	3	3	294	17	313	2e-86	273
rs:XP_009935551	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Opisthocomus hoazin].	51.01	298	139	3	3	294	13	309	2e-86	273
rs:WP_025515820	methenyltetrahydrofolate cyclohydrolase [Bordetella trematum].	49.49	293	137	4	1	293	1	282	2e-86	272
gpu:CP009516_3064	Methylenetetrahydrofolate dehydrogenase (NADP+) [Methanosarcina horonobensis HB-1]	48.11	291	140	2	3	293	8	287	2e-86	272
rs:WP_039809609	5,10-methylene-tetrahydrofolate cyclohydrolase [Jeotgalibacillus sp. D5].	48.11	291	138	3	1	291	1	278	2e-86	272
tr:A0A0D6JP21_9EURY	SubName: Full=Bifunctional protein FolD protein {ECO:0000313|EMBL:CQR49677.1};	49.65	288	143	2	5	292	4	289	2e-86	273
rs:WP_003750502	methenyltetrahydrofolate cyclohydrolase [Neisseria polysaccharea].	50.17	289	134	2	1	289	1	279	2e-86	272
rs:WP_023612782	tetrahydrofolate dehydrogenase [Streptococcus pyogenes].	47.77	291	142	2	4	294	3	283	2e-86	272
rs:WP_013916399	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus mucilaginosus].	49.32	292	137	4	1	292	1	281	2e-86	272
rs:WP_027970634	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus castoreus].	49.66	290	136	3	4	293	3	282	2e-86	272
rs:WP_026569991	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillaceae].	49.83	291	135	4	1	291	1	280	2e-86	272
rs:WP_025423101	methenyltetrahydrofolate cyclohydrolase [Sodalis praecaptivus].	50.34	290	134	3	1	290	1	280	2e-86	272
rs:WP_046559251	methenyltetrahydrofolate cyclohydrolase [Arsukibacterium ikkense].	50.00	290	135	3	1	290	1	280	2e-86	272
rs:WP_033699110	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. WCS358].	48.45	291	140	2	1	291	1	281	2e-86	272
rs:WP_047211589	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus agalactiae].	48.97	290	138	3	4	293	3	282	2e-86	272
rs:WP_020960528	5,10-methylene-tetrahydrofolate dehydrogenase [Geobacillus sp. JF8].	50.17	291	134	4	1	291	1	280	2e-86	272
rs:WP_021951414	bifunctional protein FolD [Clostridium sp. CAG:678].	51.22	287	129	4	4	290	2	277	2e-86	272
rs:XP_008333548	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Cynoglossus semilaevis].	50.00	304	144	5	1	297	28	330	2e-86	274
rs:WP_043746784	methenyltetrahydrofolate cyclohydrolase [Thauera sp. SWB20].	48.97	292	142	3	1	292	1	285	2e-86	272
rs:WP_014369997	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus mucilaginosus].	48.98	294	139	4	1	294	1	283	2e-86	272
rs:WP_022189371	bifunctional protein FolD [Ruminococcus sp. CAG:177].	50.87	287	130	4	3	289	2	277	2e-86	272
rs:XP_006627281	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2-like [Lepisosteus oculatus].	49.83	295	141	4	2	290	66	359	2e-86	275
rs:XP_009504143	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Phalacrocorax carbo].	50.34	298	141	3	3	294	3	299	2e-86	273
rs:WP_008062465	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. GM78].	48.28	290	140	2	1	290	1	280	2e-86	272
rs:WP_046391931	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus uberis].	47.93	290	141	2	4	293	3	282	2e-86	272
rs:WP_019273566	methenyltetrahydrofolate cyclohydrolase [Neisseria lactamica].	50.17	289	134	2	1	289	1	279	2e-86	272
rs:WP_016400678	methylenetetrahydrofolate dehydrogenase [Agarivorans albus].	48.45	291	140	2	1	291	1	281	2e-86	272
rs:WP_006058508	5,10-methylene-tetrahydrofolate dehydrogenase [Holdemania filiformis].	50.17	289	134	2	3	291	2	280	2e-86	272
rs:WP_015763169	5,10-methylene-tetrahydrofolate dehydrogenase [Halomicrobium mukohataei].	48.44	289	147	2	4	292	3	289	2e-86	273
sp:FOLD_BORPD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	291	134	3	2	292	13	292	2e-86	272
rs:XP_005538450	methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase [Cyanidioschyzon merolae strain 10D].	47.28	294	147	2	2	291	116	405	2e-86	276
rs:WP_019467285	methenyltetrahydrofolate cyclohydrolase [Dyella japonica].	50.69	290	133	2	1	290	1	280	2e-86	272
rs:WP_019569626	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio sp. ALE11].	49.65	288	135	2	1	288	1	278	2e-86	272
rs:WP_019021786	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio sp. ALE23].	49.65	288	135	2	1	288	1	278	2e-86	272
rs:WP_010181338	methenyltetrahydrofolate cyclohydrolase [Glaciecola sp. HTCC2999].	49.32	292	138	2	1	292	1	282	2e-86	272
rs:WP_004612533	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Clostridiales].	49.13	289	136	3	3	291	2	279	2e-86	272
tr:W5N2G4_LEPOC	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLOCP00000014823};	49.83	295	141	4	2	290	47	340	2e-86	274
rs:WP_033762366	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	45.49	288	147	2	5	292	8	285	2e-86	272
rs:WP_014596658	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	48.28	290	140	2	1	290	1	280	2e-86	272
tr:A0A0A0AJM7_CHAVO	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KGL94709.1}; Flags: Fragment;	50.34	298	141	3	3	294	4	300	2e-86	273
rs:WP_041097153	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus badius].	47.95	292	141	4	1	292	1	281	2e-86	272
rs:WP_028077542	hypothetical protein [Solobacterium moorei].	48.96	288	136	3	4	291	3	279	2e-86	272
tr:A0A093QT07_PHACA	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFW91651.1}; Flags: Fragment;	50.34	298	141	3	3	294	4	300	2e-86	273
tr:U3K0C1_FICAL	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFALP00000008475};	51.01	298	139	3	3	294	49	345	2e-86	274
rs:WP_037296514	5,10-methylene-tetrahydrofolate cyclohydrolase [Ruminococcus flavefaciens].	49.14	291	136	4	3	292	2	281	2e-86	272
sp:FOLD_NEIMF	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.83	289	135	2	1	289	1	279	2e-86	272
rs:XP_009704072	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Cariama cristata].	50.67	298	140	3	3	294	28	324	2e-86	273
rs:WP_036301714	methenyltetrahydrofolate cyclohydrolase [Methylotenera sp. L2L1].	47.60	292	143	2	1	292	1	282	2e-86	272
rs:WP_027914581	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	48.28	290	140	2	1	290	1	280	2e-86	272
rs:WP_026063622	methenyltetrahydrofolate cyclohydrolase [Piscirickettsia salmonis].	48.81	293	137	4	1	291	1	282	2e-86	272
rs:WP_034838753	5,10-methylene-tetrahydrofolate cyclohydrolase [[Clostridium] cellulosi].	52.08	288	127	3	3	290	2	278	2e-86	272
rs:WP_027304849	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter upsaliensis].	50.69	290	130	4	5	293	3	280	2e-86	272
rs:WP_019958270	methenyltetrahydrofolate cyclohydrolase [Vitreoscilla stercoraria].	50.00	292	132	4	1	290	1	280	3e-86	272
rs:XP_008642543	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Corvus brachyrhynchos].	50.34	298	141	3	3	294	36	332	3e-86	273
rs:WP_045688598	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Hymenobacter sp. AT01-02].	47.87	282	147	0	4	285	12	293	3e-86	272
rs:XP_010107613	Bifunctional protein FolD [Morus notabilis].	47.78	293	147	2	2	292	77	365	3e-86	275
rs:WP_007977124	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. GM33].	47.93	290	141	2	1	290	1	280	3e-86	272
rs:WP_029884961	methenyltetrahydrofolate cyclohydrolase [Pseudomonas putida].	47.77	291	142	2	1	291	1	281	3e-86	272
rs:WP_003294500	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas stutzeri].	48.62	290	139	2	1	290	1	280	3e-86	272
rs:WP_004435562	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus methanolicus].	49.83	291	135	4	1	291	1	280	3e-86	272
rs:WP_044115380	5,10-methylene-tetrahydrofolate cyclohydrolase [Porphyromonas sp. KLE 1280].	45.67	289	157	0	4	292	7	295	3e-86	272
rs:WP_009682641	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. TJI-51].	47.77	291	142	2	1	291	1	281	3e-86	272
rs:XP_009885055	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Charadrius vociferus].	50.34	298	141	3	3	294	15	311	3e-86	273
rs:WP_009645658	5,10-methylene-tetrahydrofolate dehydrogenase [Selenomonas sp. CM52].	49.15	295	138	3	1	293	1	285	3e-86	272
sp:FOLD_STRU0	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.93	290	141	2	4	293	3	282	3e-86	272
sp:FOLD_LEGPH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.74	291	145	2	1	291	1	281	3e-86	272
rs:WP_043297083	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. HMP271].	48.97	290	138	2	1	290	1	280	3e-86	272
rs:WP_006001233	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfuromonas acetoxidans].	49.48	289	135	3	3	291	2	279	3e-86	272
rs:WP_046969059	methenyltetrahydrofolate cyclohydrolase [Luteibacter rhizovicinus].	50.34	290	134	2	1	290	1	280	3e-86	272
rs:WP_026639697	methenyltetrahydrofolate cyclohydrolase [Bordetella petrii].	49.65	288	134	3	5	292	1	277	3e-86	271
rs:WP_013982749	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	48.28	290	140	2	1	290	1	280	3e-86	272
rs:WP_021090044	methylenetetrahydrofolate dehydrogenase [Campylobacter concisus].	52.07	290	128	4	4	293	2	280	3e-86	272
rs:WP_021090792	methylenetetrahydrofolate dehydrogenase [Campylobacter concisus].	51.72	290	129	4	4	293	2	280	3e-86	272
rs:WP_028904993	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella intermedia].	46.60	294	156	1	1	294	1	293	3e-86	272
rs:WP_042155354	5,10-methylene-tetrahydrofolate cyclohydrolase [Planktothrix agardhii].	47.52	282	142	2	5	286	4	279	3e-86	272
tr:T2SDX8_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	3e-86	272
rs:WP_014536899	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.49	288	147	2	5	292	8	285	3e-86	272
rs:WP_018986914	methenyltetrahydrofolate cyclohydrolase [Methylophilus methylotrophus].	49.31	288	136	2	1	288	1	278	3e-86	272
rs:WP_028447631	methenyltetrahydrofolate cyclohydrolase [Chitinimonas koreensis].	48.79	289	138	2	1	289	1	279	3e-86	272
rs:WP_027469966	methenyltetrahydrofolate cyclohydrolase [Deefgea rivuli].	50.35	286	132	2	1	286	1	276	3e-86	272
rs:WP_020183410	methenyltetrahydrofolate cyclohydrolase [Methylotenera sp. 1P/1].	48.26	288	139	2	1	288	1	278	3e-86	272
rs:WP_023928865	hypothetical protein [Helicobacter canis].	49.13	289	130	5	5	290	3	277	3e-86	272
rs:WP_000137499	bifunctional protein FolD [Streptococcus agalactiae].	48.62	290	139	3	4	293	3	282	3e-86	272
rs:WP_008337386	5,10-methylene-tetrahydrofolate dehydrogenase [Sulfurimonas gotlandica].	47.39	287	141	2	4	290	2	278	3e-86	272
rs:WP_046970796	methenyltetrahydrofolate cyclohydrolase [Dyella japonica].	51.40	286	129	2	1	286	1	276	3e-86	272
rs:WP_046054152	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.28	290	140	2	1	290	1	280	3e-86	272
rs:WP_038654267	5,10-methylene-tetrahydrofolate cyclohydrolase [Mucinivorans hirudinis].	47.39	287	145	2	5	291	3	283	3e-86	272
rs:WP_033147971	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella sp. P6B1].	49.83	291	145	1	4	294	2	291	3e-86	272
rs:WP_015143769	5,10-methylene-tetrahydrofolate dehydrogenase [Pleurocapsa minor].	48.42	285	141	2	2	286	5	283	3e-86	272
rs:WP_021087707	methylenetetrahydrofolate dehydrogenase [Campylobacter concisus].	52.26	287	126	4	4	290	2	277	3e-86	271
rs:WP_005225051	methenyltetrahydrofolate cyclohydrolase [Marichromatium purpuratum].	50.00	290	135	3	1	290	1	280	3e-86	272
rs:WP_017687597	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus sp. PAMC 26794].	50.34	292	134	4	1	292	1	281	3e-86	272
rs:WP_028397945	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. FJAT-14578].	49.66	290	135	4	1	290	1	279	3e-86	271
rs:WP_004974400	5,10-methylene-tetrahydrofolate dehydrogenase [Haloferax gibbonsii].	49.65	288	143	2	5	292	4	289	3e-86	272
gp:CP002221_615	Methylenetetrahydrofolate dehydrogenase (NADP(+)) [Hydrogenobacter thermophilus TK-6]	50.52	291	130	4	5	293	7	285	3e-86	272
rs:WP_028634546	methenyltetrahydrofolate cyclohydrolase [Pseudomonas parafulva].	47.42	291	143	2	1	291	1	281	3e-86	271
rs:WP_028373503	methenyltetrahydrofolate cyclohydrolase [Legionella lansingensis].	46.92	292	145	2	1	292	1	282	3e-86	271
rs:WP_027249765	5,10-methylene-tetrahydrofolate cyclohydrolase [Planktothrix agardhii].	47.52	282	142	2	5	286	4	279	3e-86	272
rs:WP_022413301	bifunctional protein FolD [Clostridium sp. CAG:470].	47.46	295	144	3	3	297	2	285	3e-86	271
sp:FOLD_STRP3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.77	291	142	2	4	294	3	283	3e-86	271
rs:WP_021982989	bifunctional protein FolD [Eubacterium sp. CAG:603].	51.39	288	129	4	3	290	2	278	3e-86	271
gp:CP000003_1254	Methylenetetrahydrofolate dehydrogenase (NADP+) [Streptococcus pyogenes MGAS10394]	47.77	291	142	2	4	294	5	285	3e-86	271
rs:WP_042727840	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	47.93	290	141	2	1	290	1	280	3e-86	271
rs:WP_009205515	methenyltetrahydrofolate cyclohydrolase [Sulfuricella denitrificans].	46.39	291	146	2	1	291	1	281	3e-86	271
rs:WP_018507539	methenyltetrahydrofolate cyclohydrolase [Thiobacillus thioparus].	48.79	289	138	2	1	289	1	279	3e-86	271
rs:WP_003289608	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	48.62	290	139	2	1	290	1	280	3e-86	271
rs:WP_028684414	methenyltetrahydrofolate cyclohydrolase [Phaseolibacter flectens].	48.97	292	139	2	1	292	1	282	3e-86	271
rs:WP_042964434	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	3e-86	272
rs:WP_019506257	methenyltetrahydrofolate cyclohydrolase [Pleurocapsa sp. PCC 7319].	48.79	289	139	3	1	286	1	283	3e-86	272
rs:WP_025746504	5,10-methylene-tetrahydrofolate cyclohydrolase [Caldicoprobacter oshimai].	48.80	291	137	3	1	291	1	279	3e-86	271
rs:WP_022127365	bifunctional protein FolD [Ruminococcus sp. CAG:579].	51.39	288	129	4	3	290	2	278	3e-86	271
rs:WP_021767636	tetrahydrofolate dehydrogenase [Leptotrichia sp. oral taxon 215].	49.13	289	135	3	6	293	4	281	3e-86	271
rs:WP_013043064	5,10-methylene-tetrahydrofolate dehydrogenase [Coraliomargarita akajimensis].	47.24	290	149	2	4	292	2	288	3e-86	272
rs:XP_011581582	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Aquila chrysaetos canadensis].	50.34	298	141	3	3	294	53	349	3e-86	274
rs:WP_000137500	tetrahydrofolate dehydrogenase [Streptococcus agalactiae].	48.97	290	138	3	4	293	3	282	3e-86	271
rs:WP_026494743	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. WCD3002].	50.87	289	133	3	1	289	1	280	3e-86	271
rs:WP_046388738	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus uberis].	47.93	290	141	2	4	293	3	282	3e-86	271
rs:WP_029937550	methenyltetrahydrofolate cyclohydrolase [Thiomicrospira sp. MA2-6].	48.44	289	139	2	1	289	1	279	3e-86	271
rs:WP_018029393	tetrahydrofolate dehydrogenase [Streptococcus ferus].	48.62	290	139	2	4	293	3	282	3e-86	271
rs:XP_010281479	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Phaethon lepturus].	50.34	298	141	3	3	294	3	299	4e-86	272
rs:WP_015120451	5,10-methylene-tetrahydrofolate dehydrogenase [Rivularia sp. PCC 7116].	47.37	285	144	2	2	286	5	283	4e-86	272
rs:WP_027846000	5,10-methylene-tetrahydrofolate cyclohydrolase [Mastigocoleus testarum].	50.18	285	136	2	2	286	5	283	4e-86	272
gpu:CP011509_6624	Methylenetetrahydrofolate dehydrogenase [Archangium gephyra]	48.97	290	137	3	3	292	2	280	4e-86	271
tr:A0A091T5X6_PHALP	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFQ69245.1}; Flags: Fragment;	50.34	298	141	3	3	294	4	300	4e-86	272
rs:WP_012963272	5,10-methylene-tetrahydrofolate dehydrogenase [Hydrogenobacter thermophilus].	50.52	291	130	4	5	293	4	282	4e-86	271
rs:WP_004044681	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Haloferax].	49.65	288	143	2	5	292	4	289	4e-86	272
rs:WP_014282224	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus terrae].	50.34	292	134	4	1	292	1	281	4e-86	271
rs:XP_002302571	hypothetical protein POPTR_0002s15850g [Populus trichocarpa].	49.15	293	143	2	2	292	75	363	4e-86	274
rs:WP_021086429	methylenetetrahydrofolate dehydrogenase [Campylobacter concisus].	52.07	290	128	4	4	293	2	280	4e-86	271
rs:WP_027421766	methenyltetrahydrofolate cyclohydrolase [Lachnobacterium bovis].	48.96	288	136	3	3	290	2	278	4e-86	271
rs:WP_028907132	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella ruminicola].	49.83	291	145	1	4	294	2	291	4e-86	271
sp:FOLD_GEODF	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.10	289	139	3	3	291	2	279	4e-86	271
rs:WP_036513723	methenyltetrahydrofolate cyclohydrolase [Nitrincola sp. AK23].	48.79	289	138	2	1	289	1	279	4e-86	271
rs:WP_022091717	bifunctional protein FolD [Lachnospiraceae bacterium CAG:25].	49.48	287	134	3	4	290	2	277	4e-86	271
rs:WP_024112509	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.83	288	146	2	5	292	8	285	4e-86	271
rs:WP_018136746	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter curvus].	51.39	288	129	4	4	291	2	278	4e-86	271
rs:WP_017649474	tetrahydrofolate dehydrogenase [Streptococcus agalactiae].	48.97	290	138	3	4	293	3	282	4e-86	271
rs:WP_006441310	5,10-methylene-tetrahydrofolate dehydrogenase [[Clostridium] hylemonae].	49.48	289	135	3	3	291	2	279	4e-86	271
rs:WP_036546181	methenyltetrahydrofolate cyclohydrolase [Nitrincola lacisaponensis].	48.44	289	139	2	1	289	1	279	4e-86	271
sp:FOLD_PSEU5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.28	290	140	2	1	290	1	280	4e-86	271
rs:WP_004367528	5,10-methylene-tetrahydrofolate dehydrogenase [Thauera phenylacetica].	49.32	292	141	3	1	292	1	285	4e-86	272
rs:WP_033151137	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella sp. RM4].	49.83	291	145	1	4	294	2	291	4e-86	271
rs:WP_046043051	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	47.93	290	141	2	1	290	1	280	4e-86	271
rs:WP_017757538	hypothetical protein [Pseudacidovorax intermedius].	50.17	291	134	4	1	291	1	280	4e-86	271
rs:WP_034098858	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens group].	48.62	290	139	2	1	290	1	280	4e-86	271
rs:WP_023051866	tetrahydrofolate dehydrogenase [Cetobacterium somerae].	49.65	288	134	4	4	290	2	279	4e-86	271
rs:WP_045004903	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	45.49	288	147	2	5	292	8	285	4e-86	271
rs:WP_001133664	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.83	288	146	2	5	292	8	285	4e-86	271
rs:WP_018144036	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio].	50.00	288	134	2	1	288	1	278	4e-86	271
rs:WP_028518336	5,10-methylene-tetrahydrofolate cyclohydrolase [Ruminococcus flavefaciens].	48.28	290	140	2	3	292	2	281	4e-86	271
sp:FOLD_LEGPA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.39	291	146	2	1	291	1	281	4e-86	271
rs:WP_019593686	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio].	50.00	288	134	2	1	288	1	278	4e-86	271
rs:WP_007273286	5,10-methylene-tetrahydrofolate dehydrogenase [Haloferax sulfurifontis].	49.65	288	143	2	5	292	4	289	4e-86	272
rs:WP_039691054	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus equinus].	50.17	291	135	3	3	293	2	282	4e-86	271
rs:WP_014235218	5,10-methylene-tetrahydrofolate dehydrogenase [Azospira oryzae].	48.45	291	139	3	1	291	1	280	4e-86	271
rs:XP_010197861	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Colius striatus].	50.67	298	140	3	3	294	36	332	4e-86	273
tr:A0A093J3W0_FULGA	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFW06552.1}; Flags: Fragment;	50.67	298	140	3	3	294	4	300	4e-86	272
rs:WP_044919115	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium MA2020].	50.52	289	134	3	4	292	2	281	4e-86	271
rs:WP_043107460	methenyltetrahydrofolate cyclohydrolase [endosymbiont of unidentified scaly snail isolate Monju].	48.62	290	139	2	1	290	1	280	4e-86	271
rs:WP_021673703	tetrahydrofolate dehydrogenase [Streptococcus sobrinus].	48.46	293	141	2	1	293	1	283	4e-86	271
rs:XP_009568525	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Cuculus canorus].	51.01	298	139	3	3	294	37	333	5e-86	273
rs:WP_008148421	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. GM41(2012)].	48.28	290	140	2	1	290	1	280	5e-86	271
rs:WP_028765550	methenyltetrahydrofolate cyclohydrolase [Shewanella colwelliana].	49.14	291	138	2	1	291	1	281	5e-86	271
tr:C1BL25_OSMMO	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:ACO09728.1};	49.83	295	141	3	3	291	30	323	5e-86	273
rs:WP_003325474	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus subtilis group].	47.78	293	142	4	1	293	1	282	5e-86	271
rs:WP_019946611	hypothetical protein [Hymenobacter aerophilus].	47.42	291	153	0	4	294	11	301	5e-86	272
rs:WP_008425901	5,10-methylene-tetrahydrofolate dehydrogenase [Natronococcus jeotgali].	48.60	286	145	2	4	289	3	286	5e-86	271
rs:WP_019621761	methenyltetrahydrofolate cyclohydrolase [Amphritea japonica].	51.03	292	133	2	1	292	1	282	5e-86	271
rs:WP_031528033	5,10-methylene-tetrahydrofolate cyclohydrolase [Dyadobacter crusticola].	44.52	292	162	0	4	295	2	293	5e-86	271
rs:WP_003799710	5,10-methylene-tetrahydrofolate dehydrogenase [Alcaligenes faecalis].	50.34	292	135	2	1	292	1	282	5e-86	271
rs:WP_047200556	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus agalactiae].	48.28	290	140	2	4	293	3	282	5e-86	271
rs:WP_029505966	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [unclassified Lachnospiraceae].	51.75	286	127	4	3	288	2	276	5e-86	271
rs:WP_002926688	5,10-methylene-tetrahydrofolate dehydrogenase [Thauera sp. 28].	49.32	292	141	3	1	292	1	285	5e-86	271
tr:I9XAD3_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.14	288	148	2	5	292	8	285	5e-86	271
rs:WP_013387133	5,10-methylene-tetrahydrofolate dehydrogenase [Ilyobacter polytropus].	48.62	290	138	4	5	293	3	282	5e-86	271
rs:WP_019899899	methenyltetrahydrofolate cyclohydrolase [Methylotenera mobilis].	47.95	292	142	2	1	292	1	282	5e-86	271
rs:WP_003183181	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	47.93	290	141	2	1	290	1	280	5e-86	271
rs:WP_033844159	5,10-methylene-tetrahydrofolate cyclohydrolase [Geobacillus subterraneus].	50.86	291	132	4	1	291	1	280	5e-86	271
rs:WP_033057296	methenyltetrahydrofolate cyclohydrolase [Pseudomonas mandelii].	48.28	290	140	2	1	290	1	280	5e-86	271
rs:WP_001133636	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.49	288	147	2	5	292	8	285	5e-86	271
rs:WP_017799359	methenyltetrahydrofolate cyclohydrolase [Erwinia toletana].	50.86	291	133	3	1	291	1	281	5e-86	271
rs:WP_016352965	5,10-methylene-tetrahydrofolate dehydrogenase [Spiribacter salinus].	50.00	290	135	2	1	290	1	280	5e-86	271
rs:WP_015331883	methenyltetrahydrofolate cyclohydrolase [Fibrella aestuarina].	44.48	290	161	0	5	294	3	292	5e-86	271
rs:WP_034044306	5,10-methylene-tetrahydrofolate cyclohydrolase [Flaviramulus ichthyoenteri].	46.69	287	153	0	5	291	3	289	5e-86	271
rs:WP_013780414	5,10-methylene-tetrahydrofolate dehydrogenase [Mahella australiensis].	47.75	289	140	2	1	289	1	278	5e-86	271
rs:WP_027432956	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium MD2004].	51.75	286	127	4	3	288	2	276	5e-86	271
rs:WP_016518325	hypothetical protein [Treponema vincentii].	46.53	288	149	2	3	290	2	284	5e-86	272
rs:WP_019648405	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. 45MFCol3.1].	47.93	290	141	2	1	290	1	280	5e-86	271
rs:XP_006018842	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Alligator sinensis].	50.84	297	139	3	3	293	7	302	5e-86	272
rs:WP_008034109	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	48.28	290	140	2	1	290	1	280	5e-86	271
rs:WP_044236613	methenyltetrahydrofolate cyclohydrolase [Chondromyces apiculatus].	48.46	293	141	2	1	293	1	283	5e-86	271
rs:WP_032630155	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	48.97	290	138	2	1	290	1	280	5e-86	271
rs:WP_028355483	methenyltetrahydrofolate cyclohydrolase [Bordetella petrii].	49.83	291	135	3	2	292	11	290	5e-86	271
rs:WP_035461995	hypothetical protein [Alicyclobacillus macrosporangiidus].	53.17	284	120	3	3	286	4	274	5e-86	271
rs:WP_046389532	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus uberis].	47.93	290	141	2	4	293	3	282	5e-86	271
rs:WP_017647831	tetrahydrofolate dehydrogenase [Streptococcus agalactiae].	48.62	290	139	3	4	293	3	282	5e-86	271
rs:WP_014537091	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.49	288	147	2	5	292	8	285	5e-86	271
rs:WP_026807485	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Arcobacter].	48.42	285	137	3	5	289	3	277	5e-86	271
rs:XP_002948919	hypothetical protein VOLCADRAFT_109691 [Volvox carteri f. nagariensis].	48.81	295	145	2	1	293	38	328	5e-86	274
rs:WP_027967925	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus equinus].	50.17	291	135	3	3	293	2	282	5e-86	271
rs:WP_022514469	bifunctional protein FolD [Roseburia sp. CAG:182].	50.17	291	134	4	3	293	2	281	5e-86	271
rs:WP_006685635	methenyltetrahydrofolate cyclohydrolase [Citrobacter youngae].	51.56	289	130	3	1	289	1	279	5e-86	271
rs:XP_005243291	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Falco peregrinus].	51.01	298	139	3	3	294	22	318	6e-86	272
rs:WP_040156430	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	6e-86	271
rs:WP_001871862	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	6e-86	271
rs:XP_010057539	PREDICTED: bifunctional protein FolD 4, chloroplastic-like isoform X1 [Eucalyptus grandis].	49.83	293	141	2	2	292	70	358	6e-86	273
rs:WP_000525734	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	6e-86	271
rs:WP_029623920	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Sphingomonas sp. JGI 0001003-C6].	49.09	275	140	0	5	279	3	277	6e-86	271
rs:WP_018361507	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella nanceiensis].	48.97	292	146	2	4	294	2	291	6e-86	271
rs:WP_036813798	methenyltetrahydrofolate cyclohydrolase [Polaromonas sp. CG9_12].	49.14	291	142	3	1	291	1	285	6e-86	271
tr:A0A0B2NVY7_GLYSO	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:KHM99402.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KHM99402.1}; EC=3.5.4.9 {ECO:0000313|EMBL:KHM99402.1};	47.95	292	146	2	2	291	4	291	6e-86	271
rs:WP_014853041	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	49.31	290	137	2	1	290	1	280	6e-86	271
rs:WP_033788073	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	6e-86	271
rs:WP_032126160	methenyltetrahydrofolate cyclohydrolase [Piscirickettsia salmonis].	48.46	293	138	4	1	291	1	282	6e-86	271
rs:WP_024852472	methenyltetrahydrofolate cyclohydrolase [[Ruminococcus] gnavus].	50.00	288	133	3	3	290	2	278	6e-86	271
rs:WP_018969083	5,10-methylene-tetrahydrofolate dehydrogenase [Rubritalea marina].	49.65	286	140	3	6	290	4	286	6e-86	271
rs:WP_015219080	5,10-methylene-tetrahydrofolate dehydrogenase [Cyanobacterium aponinum].	49.47	285	138	3	1	285	1	279	6e-86	271
rs:WP_028893422	methenyltetrahydrofolate cyclohydrolase [Syntrophorhabdus aromaticivorans].	47.93	290	150	1	1	290	1	289	6e-86	271
rs:WP_019233169	methenyltetrahydrofolate cyclohydrolase [Legionella anisa].	48.79	289	138	2	1	289	1	279	6e-86	271
rs:WP_035634941	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium ND2006].	51.40	286	130	4	4	289	2	278	6e-86	271
rs:WP_008392953	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Clostridiales].	49.48	287	134	3	4	290	2	277	6e-86	271
tr:T5D629_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.18	288	145	2	5	292	8	285	6e-86	271
tr:I9PW44_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.14	288	148	2	5	292	8	285	6e-86	271
rs:WP_017815278	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus sp. A9].	49.32	292	137	4	1	292	1	281	6e-86	271
sp:FOLD_PSEE4	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.77	291	142	2	1	291	1	281	6e-86	271
rs:WP_003199858	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	47.93	290	141	2	1	290	1	280	6e-86	271
rs:WP_021785508	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas putida group].	47.77	291	142	2	1	291	1	281	6e-86	271
sp:FOLD_BACCN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.32	294	138	4	1	294	1	283	7e-86	271
rs:WP_023413491	methenyltetrahydrofolate cyclohydrolase [uncultured Thiohalocapsa sp. PB-PSB1].	49.31	288	136	3	1	288	1	278	7e-86	271
rs:WP_046718185	methenyltetrahydrofolate cyclohydrolase [Myxococcus fulvus].	47.08	291	150	3	3	292	2	289	7e-86	271
rs:WP_001133635	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	7e-86	271
rs:WP_044747876	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus alveayuensis].	49.32	292	137	4	1	292	1	281	7e-86	271
rs:XP_010246848	PREDICTED: bifunctional protein FolD 4, chloroplastic [Nelumbo nucifera].	48.81	293	144	2	2	292	70	358	7e-86	273
tr:K8D425_CROSK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	54.79	261	108	3	28	288	10	260	7e-86	270
rs:WP_017051318	methenyltetrahydrofolate cyclohydrolase, partial [Vibrio genomosp. F6].	53.05	262	113	3	30	291	1	252	7e-86	270
gpu:CP006003_5341	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase [Myxococcus fulvus 124B02]	47.08	291	150	3	3	292	6	293	7e-86	271
rs:XP_009577990	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Fulmarus glacialis].	50.67	298	140	3	3	294	10	306	7e-86	271
rs:WP_012961632	MULTISPECIES: tetrahydrofolate dehydrogenase [Streptococcus].	49.83	291	136	2	3	293	2	282	7e-86	271
rs:WP_029636149	5,10-methylene-tetrahydrofolate cyclohydrolase [[Scytonema hofmanni] UTEX B 1581].	47.72	285	143	2	2	286	5	283	7e-86	271
rs:XP_005284051	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Chrysemys picta bellii].	51.01	298	139	3	3	294	41	337	7e-86	273
rs:WP_022374610	bifunctional protein FolD [Firmicutes bacterium CAG:270].	49.48	287	134	3	4	290	2	277	7e-86	271
tr:D3TPH5_GLOMM	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:ADD19603.1};	49.83	295	141	4	3	291	8	301	7e-86	271
rs:WP_000525729	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	7e-86	271
rs:WP_033075933	methenyltetrahydrofolate cyclohydrolase [Thalassotalea sp. ND16A].	48.80	291	139	2	1	291	1	281	7e-86	271
rs:WP_015058419	tetrahydrofolate dehydrogenase [Streptococcus agalactiae].	48.62	290	139	3	4	293	3	282	7e-86	271
rs:WP_027618774	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. URHB0015].	48.28	290	140	2	1	290	1	280	7e-86	271
rs:WP_021092894	methylenetetrahydrofolate dehydrogenase [Campylobacter concisus].	52.07	290	128	4	4	293	2	280	7e-86	271
rs:WP_014999034	methenyltetrahydrofolate cyclohydrolase [Alteromonas macleodii].	49.14	291	138	2	1	291	1	281	7e-86	271
gpu:CP011020_4998	methenyltetrahydrofolate cyclohydrolase [Pseudomonas chlororaphis]	47.59	290	142	2	1	290	1	280	7e-86	271
sp:FOLD2_PSEPK	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.77	291	142	2	1	291	1	281	7e-86	271
rs:WP_010166832	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. PAMC 25886].	48.62	290	139	2	1	290	1	280	7e-86	271
rs:WP_017840290	5,10-methylene-tetrahydrofolate dehydrogenase [Methylomicrobium buryatense].	50.68	292	133	3	1	292	1	281	7e-86	271
rs:WP_004226716	tetrahydrofolate dehydrogenase [Streptococcus criceti].	48.46	293	141	2	1	293	1	283	7e-86	271
rs:WP_036524039	methenyltetrahydrofolate cyclohydrolase [Nitrincola sp. A-D6].	49.14	291	138	2	1	291	1	281	7e-86	271
rs:WP_003238271	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas fluorescens].	48.97	290	138	2	1	290	1	280	7e-86	271
rs:WP_023605176	bifunctional protein FolD [Streptococcus pyogenes].	47.42	291	143	2	4	294	3	283	8e-86	271
sp:FOLD_PSEPW	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.77	291	142	2	1	291	1	281	8e-86	271
rs:WP_017460766	methenyltetrahydrofolate cyclohydrolase [Dyella ginsengisoli].	51.40	286	129	2	1	286	1	276	8e-86	271
rs:WP_029190290	methenyltetrahydrofolate cyclohydrolase [Verrucomicrobium spinosum].	51.03	292	139	4	4	293	2	291	8e-86	271
rs:WP_042301077	methenyltetrahydrofolate cyclohydrolase [Burkholderia kururiensis].	48.63	292	139	3	1	292	1	281	8e-86	271
rs:WP_022576732	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	8e-86	271
rs:XP_010057540	PREDICTED: bifunctional protein FolD 4, chloroplastic-like isoform X2 [Eucalyptus grandis].	49.83	293	141	2	2	292	68	356	8e-86	273
rs:WP_001133644	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	8e-86	271
tr:A0A068YTI2_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.14	291	142	3	1	291	6	290	8e-86	271
rs:WP_001916612	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	8e-86	271
tr:A0A093HWC7_STRCA	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFV85931.1}; Flags: Fragment;	50.34	298	141	3	3	294	4	300	8e-86	271
rs:WP_008436268	methenyltetrahydrofolate cyclohydrolase [Rhodanobacter thiooxydans].	51.03	290	132	2	1	290	1	280	8e-86	271
rs:WP_005789300	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	48.62	290	139	2	1	290	1	280	8e-86	271
rs:WP_000525721	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	46.18	288	145	2	5	292	10	287	8e-86	271
rs:XP_001954761	GF18431 [Drosophila ananassae].	47.16	299	145	4	3	292	2	296	8e-86	271
rs:WP_046500801	methenyltetrahydrofolate cyclohydrolase [Filomicrobium sp. Y].	48.12	293	142	2	1	293	1	283	8e-86	271
rs:WP_008016222	bifunctional protein FolD [Pseudomonas sp. GM55].	47.93	290	141	2	1	290	1	280	8e-86	271
rs:WP_017245070	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	47.93	290	141	2	1	290	1	280	8e-86	271
rs:WP_046242406	5,10-methylene-tetrahydrofolate cyclohydrolase [Hymenobacter sp. MIMtkLc17].	46.26	294	158	0	1	294	5	298	8e-86	271
rs:WP_047228500	methenyltetrahydrofolate cyclohydrolase [Pseudomonas brassicacearum].	47.93	290	141	2	1	290	1	280	8e-86	270
rs:WP_017454040	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Herbaspirillum].	48.63	292	139	3	1	292	1	281	8e-86	270
rs:WP_042237848	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. FSL R5-0912].	48.80	291	138	4	1	291	1	280	8e-86	271
rs:WP_027898465	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	48.62	290	139	2	1	290	1	280	8e-86	270
rs:WP_021943806	bifunctional protein FolD [Clostridium sp. CAG:264].	51.41	284	127	4	3	286	2	274	8e-86	270
rs:WP_039295513	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. IHB B 3415].	48.80	291	138	4	1	291	1	280	8e-86	271
rs:WP_008570175	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. Chol1].	48.62	290	139	2	1	290	1	280	8e-86	270
rs:WP_015534883	5,10-methylene-tetrahydrofolate dehydrogenase [Coprococcus sp. CAG:131].	51.59	283	126	4	4	286	3	274	9e-86	270
rs:WP_001133990	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.49	288	147	2	5	292	8	285	9e-86	271
rs:WP_019772352	tetrahydrofolate dehydrogenase [Streptococcus sobrinus].	48.46	293	141	2	1	293	1	283	9e-86	270
rs:WP_007965366	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. GM30].	47.93	290	141	2	1	290	1	280	9e-86	270
rs:WP_003207853	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	48.62	290	139	2	1	290	1	280	9e-86	270
rs:WP_020149475	hypothetical protein [Verrucomicrobia bacterium SCGC AAA164-E04].	45.21	292	158	2	4	294	5	295	9e-86	271
rs:WP_047342197	5,10-methylene-tetrahydrofolate cyclohydrolase [Enterococcus cecorum].	50.17	287	132	4	5	291	3	278	9e-86	270
rs:WP_002851045	5,10-methylene-tetrahydrofolate dehydrogenase [Ruminococcus albus].	51.90	289	128	4	3	291	2	279	9e-86	270
rs:WP_033750144	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	9e-86	271
rs:WP_038617592	methenyltetrahydrofolate cyclohydrolase [Dyella jiangningensis].	50.34	290	134	2	1	290	1	280	9e-86	271
rs:WP_019692760	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	47.93	290	141	2	1	290	1	280	9e-86	270
tr:A0A023EP26_AEDAL	SubName: Full=Putative c1-tetrahydrofolate synthase {ECO:0000313|EMBL:JAC10715.1}; Flags: Fragment;	49.66	290	138	4	8	290	3	291	9e-86	271
rs:WP_025690978	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus zanthoxyli].	50.17	291	134	3	1	291	1	280	9e-86	270
rs:WP_019795743	tetrahydrofolate dehydrogenase [Streptococcus sobrinus].	48.46	293	141	2	1	293	1	283	9e-86	270
rs:WP_000226718	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus].	50.68	292	133	4	1	292	1	281	9e-86	270
rs:WP_008576228	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Haloferax].	49.65	288	143	2	5	292	4	289	9e-86	271
rs:WP_033019350	5,10-methylene-tetrahydrofolate cyclohydrolase [Geobacillus sp. G1w1].	50.86	291	132	4	1	291	1	280	9e-86	270
tr:A0A091WH86_NIPNI	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFR00921.1}; Flags: Fragment;	50.34	298	141	3	3	294	4	300	9e-86	271
rs:WP_045666297	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. BRH_c35].	48.28	290	140	2	1	290	1	280	9e-86	270
tr:Q6JWS5_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.14	291	137	4	1	291	1	280	9e-86	270
rs:XP_010210019	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Tinamus guttatus].	50.00	298	142	3	3	294	26	322	1e-85	272
rs:WP_042145866	5,10-methylene-tetrahydrofolate cyclohydrolase [Paucisalibacillus sp. EB02].	46.08	293	147	3	1	293	1	282	1e-85	270
rs:WP_025255890	methenyltetrahydrofolate cyclohydrolase [Alteromonas sp. ALT199].	48.80	291	139	2	1	291	1	281	1e-85	270
rs:WP_044912718	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. WCE2006].	49.12	285	136	2	5	289	3	278	1e-85	270
rs:WP_026483301	methenyltetrahydrofolate cyclohydrolase [Alcaligenes faecalis].	50.00	292	136	2	1	292	1	282	1e-85	270
rs:WP_016500563	MULTISPECIES: methylenetetrahydrofolate dehydrogenase [Pseudomonas].	48.45	291	140	2	1	291	1	281	1e-85	270
rs:WP_002939540	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter concisus].	51.72	290	129	4	4	293	2	280	1e-85	270
rs:WP_001133659	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.83	288	146	2	5	292	8	285	1e-85	270
tr:A0A0C1JT40_9CHLA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.60	294	153	2	1	293	1	291	1e-85	271
rs:WP_034414483	methenyltetrahydrofolate cyclohydrolase [Candidatus Photodesmus blepharus].	49.13	289	137	3	1	289	1	279	1e-85	270
rs:WP_018949875	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio sp. ALMg11].	50.00	288	134	2	1	288	1	278	1e-85	270
rs:WP_009457053	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Alcaligenes].	50.00	292	136	2	1	292	1	282	1e-85	270
rs:WP_021666634	tetrahydrofolate dehydrogenase [Porphyromonas sp. oral taxon 278].	45.64	287	156	0	4	290	7	293	1e-85	271
tr:U7A2W5_9PSED	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.62	290	139	2	1	290	1	280	1e-85	270
rs:WP_046226754	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus dauci].	48.97	292	138	4	1	292	1	281	1e-85	270
rs:WP_024544633	5,10-methylene-tetrahydrofolate cyclohydrolase [Synechococcus sp. NKBG15041c].	47.54	284	144	2	3	286	2	280	1e-85	270
rs:WP_028998008	methenyltetrahydrofolate cyclohydrolase [Azohydromonas australica].	49.47	285	133	4	1	285	1	274	1e-85	270
rs:WP_016714772	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	48.11	291	141	2	1	291	1	281	1e-85	270
rs:WP_010653411	methenyltetrahydrofolate cyclohydrolase [Fluoribacter dumoffii].	48.44	289	139	2	1	289	1	279	1e-85	270
rs:WP_036675001	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. FSL R5-192].	49.66	292	136	3	1	292	1	281	1e-85	270
rs:WP_044500917	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. 12M76_air].	47.42	291	143	2	1	291	1	281	1e-85	270
rs:WP_010762845	FolD protein [Enterococcus haemoperoxidus].	49.31	290	136	4	3	292	2	280	1e-85	270
tr:W9UY10_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.79	289	138	2	1	289	41	319	1e-85	271
rs:WP_001133655	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.83	288	146	2	5	292	8	285	1e-85	270
rs:WP_015086809	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	1e-85	270
sp:FOLD1_PSEPG	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.77	291	142	2	1	291	7	287	1e-85	270
gp:CP007354_450	methenyltetrahydrofolate cyclohydrolase [Salmonella enterica subsp. enterica serovar Enteritidis str.]	50.69	288	132	3	1	288	1	278	1e-85	270
rs:WP_019422915	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus sp. OSY-SE].	47.77	291	141	4	1	291	1	280	1e-85	270
rs:WP_039589132	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	47.93	290	141	2	1	290	1	280	1e-85	270
rs:WP_015277091	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas stutzeri].	48.62	290	139	2	1	290	1	280	1e-85	270
rs:WP_046817994	methenyltetrahydrofolate cyclohydrolase [Pseudomonas putida].	47.93	290	141	2	1	290	1	280	1e-85	270
rs:WP_033764237	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	1e-85	270
tr:A6XGU7_9CHLO	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:ABH11015.1}; Flags: Fragment;	46.26	294	152	2	2	293	25	314	1e-85	271
rs:WP_006018384	methylenetetrahydrofolate dehydrogenase [Helicobacter bizzozeronii].	48.10	289	134	5	5	291	3	277	1e-85	270
rs:WP_013499776	5,10-methylene-tetrahydrofolate dehydrogenase [Ruminococcus albus].	52.25	289	127	4	3	291	2	279	1e-85	270
rs:WP_010209410	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	48.97	290	138	2	1	290	1	280	1e-85	270
rs:WP_024778303	methenyltetrahydrofolate cyclohydrolase [Pseudomonas corrugata].	47.93	290	141	2	1	290	1	280	1e-85	270
sp:FOLD_CHLL2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.90	290	152	1	5	292	3	292	1e-85	271
sp:FOLD_AQUAE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.63	292	138	3	3	293	2	282	1e-85	270
rs:WP_041269707	5,10-methylene-tetrahydrofolate cyclohydrolase [Geobacillus sp. WCH70].	49.32	294	138	4	1	294	1	283	1e-85	270
rs:WP_008077717	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. GM80].	48.62	290	139	2	1	290	1	280	1e-85	270
rs:WP_032461879	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus pyogenes].	47.77	291	142	2	4	294	3	283	1e-85	270
rs:XP_007139900	hypothetical protein PHAVU_008G068000g [Phaseolus vulgaris].	48.63	292	144	2	2	291	55	342	1e-85	272
rs:WP_003756027	5,10-methylene-tetrahydrofolate dehydrogenase [Listeria grayi].	50.52	289	132	4	3	291	2	279	1e-85	270
rs:WP_035384257	methenyltetrahydrofolate cyclohydrolase [Ferriphaselus sp. R-1].	48.97	292	138	3	1	292	1	281	1e-85	270
tr:J8UVH9_PSEPU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.42	291	143	2	1	291	1	281	1e-85	270
rs:WP_003063732	MULTISPECIES: tetrahydrofolate dehydrogenase [Streptococcus].	49.83	291	136	2	3	293	2	282	1e-85	270
rs:WP_017650189	tetrahydrofolate dehydrogenase [Streptococcus agalactiae].	48.62	290	139	3	4	293	3	282	1e-85	270
rs:WP_009227749	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella sp. oral taxon 299].	48.97	292	146	2	4	294	2	291	1e-85	270
rs:WP_016315231	methylenetetrahydrofolate dehydrogenase [Anaerotruncus sp. G3(2012)].	50.52	291	133	4	1	291	1	280	1e-85	270
rs:WP_017767042	tetrahydrofolate dehydrogenase, partial [Streptococcus agalactiae].	49.30	286	135	3	4	289	3	278	1e-85	270
rs:WP_022962305	methenyltetrahydrofolate cyclohydrolase [Pseudomonas pelagia].	48.62	290	139	2	1	290	1	280	1e-85	270
rs:WP_001133646	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.49	288	147	2	5	292	8	285	1e-85	270
rs:WP_027593957	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. LAIL14HWK12:I7].	47.77	291	142	2	1	291	1	281	1e-85	270
rs:WP_008980146	5,10-methylene-tetrahydrofolate dehydrogenase [Ruminococcaceae bacterium D16].	49.83	291	132	4	1	291	1	277	1e-85	270
rs:WP_041201275	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	1e-85	270
rs:WP_001133653	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	1e-85	270
rs:WP_018132468	hypothetical protein [Effusibacillus pohliae].	48.80	291	137	3	1	291	1	279	1e-85	270
tr:K2K2F7_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.49	288	147	2	5	292	8	285	1e-85	270
rs:WP_033735829	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	46.18	288	145	2	5	292	8	285	1e-85	270
rs:WP_020603381	5,10-methylene-tetrahydrofolate dehydrogenase [Spirosoma spitsbergense].	44.33	291	162	0	4	294	2	292	1e-85	270
rs:WP_044479113	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. GD11].	50.17	291	134	4	1	291	1	280	1e-85	270
rs:WP_043213476	methenyltetrahydrofolate cyclohydrolase [Pseudomonas putida].	47.77	291	142	2	1	291	1	281	1e-85	270
rs:WP_013971879	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	47.42	291	143	2	1	291	1	281	1e-85	270
tr:I6R477_PSESX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.77	291	142	2	1	291	19	299	1e-85	271
rs:WP_001133660	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	1e-85	270
rs:WP_035004684	hypothetical protein, partial [Betaproteobacteria bacterium MOLA814].	49.66	294	133	5	1	290	1	283	1e-85	270
rs:WP_042925161	methenyltetrahydrofolate cyclohydrolase [Kingella kingae].	49.31	290	137	2	1	290	1	280	1e-85	270
rs:WP_027851178	methenyltetrahydrofolate cyclohydrolase [Marinospirillum insulare].	47.78	293	143	2	1	293	1	283	1e-85	270
rs:WP_014147901	5,10-methylene-tetrahydrofolate dehydrogenase [Methylomicrobium alcaliphilum].	50.68	292	133	3	1	292	1	281	1e-85	270
tr:T2SBU8_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	1e-85	270
rs:WP_016485882	methenyltetrahydrofolate cyclohydrolase [Pseudomonas putida].	48.45	291	140	2	1	291	1	281	1e-85	270
rs:WP_012301265	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Desulforudis audaxviator].	47.77	291	141	2	1	291	1	280	1e-85	270
tr:A0A091P9I1_HALAL	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFQ03888.1}; Flags: Fragment;	49.66	298	143	3	3	294	4	300	1e-85	271
tr:E6S267_HELPF	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.14	288	148	2	5	292	15	292	1e-85	270
rs:WP_007986489	bifunctional protein FolD [Pseudomonas sp. GM48].	47.93	290	141	2	1	290	1	280	1e-85	270
rs:XP_009323174	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Pygoscelis adeliae].	50.67	298	140	3	3	294	51	347	1e-85	272
rs:XP_008376030	PREDICTED: bifunctional protein FolD 4, chloroplastic [Malus domestica].	49.32	292	142	2	2	291	71	358	1e-85	273
rs:XP_010311593	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Balearica regulorum gibbericeps].	50.34	298	141	3	3	294	44	340	1e-85	272
tr:V4YG60_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.32	296	135	5	1	292	1	285	1e-85	271
tr:C5D472_GEOSW	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.32	294	138	4	1	294	4	286	1e-85	270
gp:CP000712_3421	5,10-methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [Pseudomonas putida F1]	47.77	291	142	2	1	291	16	296	1e-85	271
rs:WP_001133648	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.49	288	147	2	5	292	8	285	1e-85	270
rs:WP_006465307	5,10-methylene-tetrahydrofolate dehydrogenase [Herbaspirillum frisingense].	49.14	291	137	3	1	291	1	280	1e-85	270
sp:FOLD_HELPY	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	1e-85	270
rs:WP_034107275	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.62	290	139	2	1	290	1	280	1e-85	270
rs:WP_042215934	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus borealis].	48.45	291	139	4	1	291	1	280	1e-85	270
rs:WP_014339305	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	47.59	290	142	2	1	290	1	280	1e-85	270
rs:WP_017136461	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.62	290	139	2	1	290	1	280	1e-85	270
rs:WP_025338415	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. FGI182].	47.42	291	143	2	1	291	1	281	1e-85	270
tr:A0A0B8V5X0_PISSA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.80	291	136	4	3	291	2	281	1e-85	270
rs:WP_004595324	5,10-methylene-tetrahydrofolate dehydrogenase [Halorubrum distributum].	51.22	287	136	4	4	289	3	286	1e-85	270
rs:WP_045060163	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. ES3-33].	47.59	290	142	2	1	290	1	280	1e-85	270
rs:WP_037563054	hypothetical protein [Spirochaeta sp. JC202].	47.77	291	151	1	1	291	1	290	1e-85	270
rs:WP_004357607	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella disiens].	46.26	294	157	1	1	294	1	293	1e-85	270
rs:WP_000525726	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.49	288	147	2	5	292	10	287	1e-85	270
rs:WP_021830763	methylenetetrahydrofolate dehydrogenase [Crocosphaera watsonii].	47.93	290	145	2	2	291	5	288	1e-85	270
rs:WP_022484309	bifunctional protein FolD [Clostridium sp. CAG:389].	47.46	295	144	3	3	297	2	285	1e-85	270
rs:WP_030140019	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	47.93	290	141	2	1	290	1	280	1e-85	270
rs:WP_028533989	methenyltetrahydrofolate cyclohydrolase [Paludibacterium yongneupense].	51.40	286	129	2	1	286	1	276	1e-85	270
rs:WP_022258699	bifunctional protein FolD [Clostridium sp. CAG:508].	51.04	288	130	4	3	290	2	278	1e-85	270
rs:WP_010458702	methenyltetrahydrofolate cyclohydrolase [Pseudomonas mandelii].	47.93	290	141	2	1	290	1	280	1e-85	270
rs:WP_015269692	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas putida].	47.42	291	143	2	1	291	1	281	1e-85	270
rs:WP_000525678	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	1e-85	270
rs:WP_015079164	methenyltetrahydrofolate cyclohydrolase [Anabaena sp. 90].	48.77	285	140	2	2	286	4	282	1e-85	270
rs:WP_014533477	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.49	288	147	2	5	292	8	285	1e-85	270
sp:FOLD_SODGM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.66	290	136	3	1	290	1	280	1e-85	270
rs:WP_036992345	methenyltetrahydrofolate cyclohydrolase [Pseudomonas bauzanensis].	47.08	291	144	2	1	291	1	281	1e-85	270
rs:WP_012529930	5,10-methylene-tetrahydrofolate dehydrogenase [Geobacter bemidjiensis].	48.11	291	140	3	3	293	2	281	1e-85	270
rs:XP_009682144	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Struthio camelus australis].	50.34	298	141	3	3	294	19	315	1e-85	271
rs:WP_007304347	methenyltetrahydrofolate cyclohydrolase [Crocosphaera watsonii].	47.93	290	145	2	2	291	8	291	1e-85	270
rs:WP_046281818	5,10-methylene-tetrahydrofolate cyclohydrolase [Limnoraphis robusta].	48.11	291	145	2	3	293	2	286	1e-85	270
rs:WP_014534227	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	1e-85	270
tr:J7MAN6_STRP1	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.42	291	143	2	4	294	5	285	1e-85	270
rs:WP_035766160	hypothetical protein [Butyrivibrio sp. NC2002].	49.12	285	136	2	1	285	1	276	1e-85	270
tr:I9Z3F6_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	1e-85	270
rs:WP_017941133	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio].	49.65	288	135	2	1	288	1	278	1e-85	270
sp:FOLD_STRP1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.42	291	143	2	4	294	3	283	1e-85	270
rs:WP_039746064	5,10-methylene-tetrahydrofolate cyclohydrolase [Hassallia byssoidea].	48.25	286	145	1	5	290	9	291	1e-85	270
rs:WP_003223627	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	47.93	290	141	2	1	290	1	280	2e-85	270
rs:WP_025138924	methenyltetrahydrofolate cyclohydrolase [Achromobacter sp. DH1f].	49.32	292	137	3	1	292	1	281	2e-85	270
rs:WP_000525732	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	2e-85	270
rs:WP_036477606	5,10-methylene-tetrahydrofolate cyclohydrolase [Myxosarcina sp. GI1].	47.40	289	143	3	1	286	1	283	2e-85	270
rs:WP_016086326	FolD protein [Bacillus cereus].	50.34	292	134	4	1	292	1	281	2e-85	270
rs:WP_007951561	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. GM25].	47.93	290	141	2	1	290	1	280	2e-85	270
rs:WP_034120381	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.62	290	139	2	1	290	1	280	2e-85	270
rs:WP_028692666	methenyltetrahydrofolate cyclohydrolase [Pseudomonas mosselii].	47.77	291	142	2	1	291	1	281	2e-85	270
rs:WP_038304066	methenyltetrahydrofolate cyclohydrolase [Kingella kingae].	48.97	290	138	2	1	290	1	280	2e-85	270
rs:WP_013742088	5,10-methylene-tetrahydrofolate dehydrogenase [Pusillimonas sp. T7-7].	48.97	292	138	4	1	292	1	281	2e-85	270
rs:WP_006219002	5,10-methylene-tetrahydrofolate dehydrogenase [Achromobacter piechaudii].	49.66	292	136	4	1	292	1	281	2e-85	270
rs:WP_039670573	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus macedonicus].	49.83	291	136	2	3	293	2	282	2e-85	270
rs:WP_017736928	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. CBZ-4].	48.62	290	139	2	1	290	1	280	2e-85	270
rs:WP_028515806	5,10-methylene-tetrahydrofolate cyclohydrolase [Ruminococcus flavefaciens].	48.28	290	140	2	3	292	2	281	2e-85	270
rs:WP_024969530	5,10-methylene-tetrahydrofolate cyclohydrolase [Microcystis aeruginosa].	47.95	292	141	2	2	293	5	285	2e-85	270
rs:WP_025855994	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. CHM02].	48.62	290	139	2	1	290	1	280	2e-85	270
rs:WP_023444354	methenyltetrahydrofolate cyclohydrolase [Pseudomonas chloritidismutans].	48.28	290	140	2	1	290	1	280	2e-85	270
rs:WP_039666828	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter sp. RM16704].	51.03	290	129	4	5	293	3	280	2e-85	270
rs:WP_014820299	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	48.28	290	140	2	1	290	1	280	2e-85	270
rs:WP_027814957	methenyltetrahydrofolate cyclohydrolase [Burkholderia bannensis].	48.97	292	138	3	1	292	1	281	2e-85	270
rs:XP_010573885	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Haliaeetus leucocephalus].	50.00	298	142	3	3	294	54	350	2e-85	272
rs:WP_007944755	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. GM21].	48.28	290	140	2	1	290	1	280	2e-85	270
rs:WP_034146815	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	47.93	290	141	2	1	290	1	280	2e-85	270
rs:WP_016965270	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	47.93	290	141	2	1	290	1	280	2e-85	270
rs:WP_009591257	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus sp. HGF5].	51.21	289	130	4	3	291	4	281	2e-85	270
rs:WP_045929912	methenyltetrahydrofolate cyclohydrolase [Alcaligenes faecalis].	50.00	292	136	2	1	292	1	282	2e-85	270
rs:WP_037596025	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus phocae].	47.93	290	141	2	4	293	3	282	2e-85	270
rs:WP_038416825	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	2e-85	270
rs:WP_029504532	methenyltetrahydrofolate cyclohydrolase [Lachnoclostridium phytofermentans].	52.25	289	127	4	3	291	2	279	2e-85	270
rs:XP_009917117	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Haliaeetus albicilla].	49.66	298	143	3	3	294	19	315	2e-85	271
sp:FOLD_HALHL	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.11	291	141	2	1	291	1	281	2e-85	270
rs:WP_007940405	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. GM18].	47.93	290	141	2	1	290	1	280	2e-85	270
tr:A0A063ZJU7_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.52	287	138	4	4	289	3	286	2e-85	270
rs:WP_040103449	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus polymyxa].	49.66	292	136	4	1	292	1	281	2e-85	270
rs:WP_003300180	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas stutzeri].	48.28	290	140	2	1	290	1	280	2e-85	270
rs:WP_033828453	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. KW-12].	50.00	290	134	4	1	290	1	279	2e-85	270
rs:WP_022465438	bifunctional protein FolD [Clostridium sp. CAG:277].	50.00	284	131	3	3	286	2	274	2e-85	270
rs:WP_018867251	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio].	49.65	288	135	2	1	288	1	278	2e-85	270
rs:WP_041074114	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. W15Feb9B].	47.93	290	141	2	1	290	1	280	2e-85	270
tr:L7Y0L2_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.32	292	137	4	1	292	1	281	2e-85	270
rs:WP_043391255	methenyltetrahydrofolate cyclohydrolase [Cystobacter violaceus].	48.80	291	138	3	3	293	2	281	2e-85	270
tr:A0A087GL83_ARAAL	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFK30635.1};	47.77	291	146	2	3	291	72	358	2e-85	272
sp:FOLD_PSEPF	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.93	290	141	2	1	290	1	280	2e-85	270
sp:FOLD_BACAA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.00	292	135	4	1	292	1	281	2e-85	270
rs:WP_028824442	5,10-methylene-tetrahydrofolate cyclohydrolase [Proteobacteria bacterium JGI 0000113-P07].	47.55	286	150	0	5	290	3	288	2e-85	270
rs:WP_001133643	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.49	288	147	2	5	292	8	285	2e-85	270
rs:WP_042480821	methenyltetrahydrofolate cyclohydrolase [Alcaligenes faecalis].	49.66	292	137	2	1	292	1	282	2e-85	270
rs:WP_026803422	5,10-methylene-tetrahydrofolate cyclohydrolase [Arcobacter sp. AF1581].	48.77	285	136	3	5	289	3	277	2e-85	270
rs:WP_039603436	bifunctional protein FolD [Pseudomonas putida].	47.77	291	142	2	1	291	1	281	2e-85	270
rs:WP_034770921	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus thermoamylovorans].	50.52	291	133	4	1	291	1	280	2e-85	270
rs:WP_017476932	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. PAMC 26793].	48.62	290	139	2	1	290	1	280	2e-85	270
rs:WP_038554468	5,10-methylene-tetrahydrofolate cyclohydrolase [Draconibacterium orientale].	49.66	290	144	1	5	294	3	290	2e-85	270
rs:WP_019580007	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	47.59	290	142	2	1	290	1	280	2e-85	270
rs:WP_009853711	tetrahydrofolate dehydrogenase [Streptococcus gallolyticus].	49.83	291	136	2	3	293	2	282	2e-85	270
rs:WP_035330004	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus firmus].	47.78	293	142	3	1	293	1	282	2e-85	270
rs:WP_045030987	5,10-methylene-tetrahydrofolate cyclohydrolase [Draconibacterium sp. JN14CK-3].	49.66	290	144	1	5	294	3	290	2e-85	270
rs:WP_027975736	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus devriesei].	49.31	290	137	2	4	293	3	282	2e-85	270
rs:WP_044876340	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. IHBB 10380].	49.14	291	137	3	1	291	1	280	2e-85	270
rs:WP_029521565	5,10-methylene-tetrahydrofolate cyclohydrolase [Persephonella sp. IF05-L8].	47.62	294	144	3	1	293	1	285	2e-85	270
rs:WP_015325642	5,10-methylene-tetrahydrofolate dehydrogenase [Methanomethylovorans hollandica].	48.79	289	137	3	2	290	25	302	2e-85	270
rs:WP_044386164	methenyltetrahydrofolate cyclohydrolase [Marinobacter excellens].	51.21	289	131	2	1	289	1	279	2e-85	270
rs:WP_006656124	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter canadensis].	47.04	287	141	4	4	290	2	277	2e-85	270
rs:WP_013218261	5,10-methylene-tetrahydrofolate dehydrogenase [Dehalogenimonas lykanthroporepellens].	45.55	292	158	1	1	292	1	291	2e-85	270
rs:WP_022760054	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Butyrivibrio].	49.82	285	134	3	5	289	3	278	2e-85	270
tr:T2SJR2_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	2e-85	270
rs:WP_030130868	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. QTF5].	47.93	290	141	2	1	290	1	280	2e-85	270
rs:WP_027606241	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. LAMO17WK12:I2].	48.28	290	140	2	1	290	1	280	2e-85	270
rs:WP_046806423	methenyltetrahydrofolate cyclohydrolase [Achromobacter sp. LC458].	49.32	292	137	4	1	292	1	281	2e-85	270
rs:WP_041972567	5,10-methylene-tetrahydrofolate cyclohydrolase [Geobacter sp. OR-1].	48.62	290	138	3	3	292	2	280	2e-85	270
rs:WP_034630427	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus okhensis].	50.17	291	133	3	1	291	1	279	2e-85	269
rs:WP_043864505	methenyltetrahydrofolate cyclohydrolase [Pseudomonas putida].	48.11	291	141	2	1	291	1	281	2e-85	270
sp:FOLD_ALTMD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.14	291	138	2	1	291	1	281	2e-85	270
rs:WP_024773383	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	2e-85	270
rs:WP_027859076	methenyltetrahydrofolate cyclohydrolase [Marinobacterium jannaschii].	48.97	292	139	2	1	292	1	282	2e-85	270
rs:WP_038418646	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	2e-85	270
rs:WP_016686514	methenyltetrahydrofolate cyclohydrolase [Neisseria sicca].	49.48	289	136	2	1	289	1	279	2e-85	269
rs:WP_035187994	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus coagulans].	48.80	291	138	4	1	291	1	280	2e-85	269
rs:WP_041864021	methenyltetrahydrofolate cyclohydrolase [Bordetella petrii].	50.00	288	133	3	5	292	1	277	2e-85	269
rs:WP_018440238	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia sp. JPY347].	50.86	291	132	4	1	291	1	280	2e-85	270
rs:XP_009070635	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Acanthisitta chloris].	49.33	298	144	3	3	294	3	299	2e-85	270
rs:XP_005144203	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Melopsittacus undulatus].	50.34	298	141	3	3	294	51	347	2e-85	271
rs:WP_013371775	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus polymyxa].	49.66	292	136	4	1	292	1	281	2e-85	270
rs:WP_009649970	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter sp. FOBRC14].	51.39	288	129	4	4	291	2	278	2e-85	270
rs:WP_017827990	tetrahydrofolate dehydrogenase [Streptococcus agalactiae].	48.62	290	139	3	4	293	3	282	2e-85	269
rs:WP_042226610	methenyltetrahydrofolate cyclohydrolase [Kingella kingae].	48.97	290	138	2	1	290	1	280	2e-85	269
rs:WP_001133989	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	2e-85	270
rs:WP_003101063	tetrahydrofolate dehydrogenase [Streptococcus iniae].	49.48	291	137	2	3	293	2	282	2e-85	270
rs:WP_026767932	5,10-methylene-tetrahydrofolate cyclohydrolase [Sediminibacterium sp. OR53].	47.89	284	148	0	5	288	3	286	2e-85	270
rs:WP_044409218	methenyltetrahydrofolate cyclohydrolase [Thioalkalimicrobium microaerophilum].	48.97	290	138	2	1	290	1	280	2e-85	269
rs:WP_022343212	bifunctional protein FolD [Clostridium sp. CAG:356].	47.39	287	140	3	4	290	2	277	2e-85	269
rs:WP_000137495	tetrahydrofolate dehydrogenase [Streptococcus agalactiae].	48.62	290	139	3	4	293	3	282	3e-85	269
rs:WP_003280799	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	48.62	290	139	2	1	290	1	280	3e-85	269
rs:WP_033601434	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	3e-85	270
rs:WP_008214609	methenyltetrahydrofolate cyclohydrolase [Rhodanobacter sp. 115].	50.00	292	136	2	1	292	1	282	3e-85	269
rs:WP_028616937	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. 2-92(2010)].	48.62	290	139	2	1	290	1	280	3e-85	269
rs:WP_025246846	methenyltetrahydrofolate cyclohydrolase [Candidatus Sodalis pierantonius].	50.34	290	134	3	1	290	1	280	3e-85	270
rs:WP_017527088	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.62	290	139	2	1	290	1	280	3e-85	269
rs:WP_023629744	methenyltetrahydrofolate cyclohydrolase [Pseudomonas mosselii].	47.77	291	142	2	1	291	1	281	3e-85	269
rs:WP_047276671	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.62	290	139	2	1	290	1	280	3e-85	269
rs:WP_009149775	methenyltetrahydrofolate cyclohydrolase [Thiorhodovibrio sp. 970].	48.97	290	138	3	1	290	1	280	3e-85	269
rs:WP_022438440	bifunctional protein FolD [Clostridium sp. CAG:411].	49.65	288	134	3	3	290	2	278	3e-85	269
rs:WP_008400760	5,10-methylene-tetrahydrofolate dehydrogenase [Clostridium sp. L2-50].	51.59	283	126	4	4	286	3	274	3e-85	269
rs:WP_047151493	5,10-methylene-tetrahydrofolate cyclohydrolase [Aneurinibacillus tyrosinisolvens].	49.14	291	137	3	1	291	1	280	3e-85	269
rs:XP_008232785	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X1 [Prunus mume].	48.11	291	145	2	3	291	69	355	3e-85	272
rs:WP_006227406	5,10-methylene-tetrahydrofolate dehydrogenase [Achromobacter piechaudii].	48.97	292	138	3	1	292	1	281	3e-85	269
rs:WP_001860488	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	3e-85	270
rs:WP_019625596	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio sp. ALJT].	50.35	288	133	2	1	288	1	278	3e-85	269
rs:WP_016782310	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fragi].	48.11	291	141	2	1	291	1	281	3e-85	269
rs:WP_046068717	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.28	290	140	2	1	290	1	280	3e-85	269
rs:WP_015187538	bifunctional protein FolD [Gloeocapsa sp. PCC 7428].	48.07	285	141	3	2	286	5	282	3e-85	270
rs:WP_016956264	methenyltetrahydrofolate cyclohydrolase [Catenovulum agarivorans].	50.00	286	133	2	1	286	1	276	3e-85	269
rs:WP_038697281	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus stellifer].	49.14	291	137	3	1	291	1	280	3e-85	269
rs:WP_015085698	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.52	292	152	2	1	292	4	285	3e-85	270
tr:R4I0Y5_9ENTR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.90	290	144	2	1	290	1	280	3e-85	269
rs:WP_007927213	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	47.93	290	141	2	1	290	1	280	3e-85	269
rs:WP_007186387	methenyltetrahydrofolate cyclohydrolase [Hydrocarboniphaga effusa].	47.42	291	143	2	1	291	1	281	3e-85	269
rs:WP_025214688	methenyltetrahydrofolate cyclohydrolase [Pseudomonas brassicacearum].	47.59	290	142	2	1	290	1	280	3e-85	269
rs:WP_039669983	methenyltetrahydrofolate cyclohydrolase [Coxiella endosymbiont of Amblyomma americanum].	46.58	292	146	2	1	292	1	282	3e-85	269
rs:WP_003441360	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	48.62	290	139	2	1	290	1	280	3e-85	269
rs:WP_004840739	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Clostridiales].	49.65	288	134	3	3	290	2	278	3e-85	269
rs:WP_040951338	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillaceae bacterium G5].	48.29	292	140	4	1	292	1	281	3e-85	269
rs:WP_033739168	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	3e-85	270
rs:XP_009237839	PREDICTED: LOW QUALITY PROTEIN: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Pongo abelii].	48.81	295	144	3	3	291	31	324	3e-85	271
rs:WP_022934409	5,10-methylene-tetrahydrofolate dehydrogenase [Synergistetes bacterium JGI 0000079-D21].	49.83	291	132	5	3	292	2	279	3e-85	269
rs:WP_022073116	bifunctional protein FolD [Anaerotruncus sp. CAG:528].	52.10	286	126	4	5	290	3	277	3e-85	269
rs:WP_022086578	bifunctional protein FolD [Roseburia sp. CAG:197].	50.35	288	132	4	3	290	2	278	3e-85	269
rs:WP_014662099	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	3e-85	269
rs:WP_025694705	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus durus].	50.17	291	134	3	1	291	1	280	3e-85	269
rs:WP_044845864	methenyltetrahydrofolate cyclohydrolase [Burkholderia sp. USM B20].	51.03	290	131	4	3	292	4	282	3e-85	269
rs:XP_003623888	Bifunctional protein folD [Medicago truncatula].	49.31	290	141	2	4	291	61	346	3e-85	271
tr:S5QW95_9STRE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.14	291	138	3	3	293	19	299	3e-85	270
rs:WP_044530870	methenyltetrahydrofolate cyclohydrolase [Herbaspirillum sp. B65].	48.29	292	140	3	1	292	1	281	3e-85	269
rs:WP_043100949	methenyltetrahydrofolate cyclohydrolase [Xanthomonadaceae bacterium 3.5X].	51.38	290	131	2	1	290	1	280	3e-85	269
rs:WP_043117260	methenyltetrahydrofolate cyclohydrolase [Solemya velum gill symbiont].	48.26	288	139	2	1	288	1	278	3e-85	269
rs:XP_002053181	GJ23482 [Drosophila virilis].	46.00	300	148	4	3	293	2	296	3e-85	270
tr:A0A0B8V8S4_PISSA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.45	291	137	4	3	291	2	281	3e-85	269
rs:WP_001133642	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	3e-85	269
rs:WP_031560017	5,10-methylene-tetrahydrofolate cyclohydrolase [Ruminococcus flavefaciens].	48.97	290	138	3	3	292	2	281	3e-85	269
rs:WP_032889913	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. RIT357].	48.62	290	139	2	1	290	1	280	3e-85	269
rs:XP_005498588	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Columba livia].	50.34	298	141	3	3	294	49	345	3e-85	271
rs:WP_033123747	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	3e-85	269
rs:WP_025683327	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. 1-49].	50.00	292	135	4	1	292	1	281	3e-85	269
rs:WP_038577705	methenyltetrahydrofolate cyclohydrolase [Pseudomonas chlororaphis].	47.93	290	141	2	1	290	1	280	3e-85	269
rs:WP_024076274	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. TKP].	47.93	290	141	2	1	290	1	280	3e-85	269
rs:WP_038848417	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.45	291	140	2	1	291	1	281	3e-85	269
rs:WP_044197763	methenyltetrahydrofolate cyclohydrolase [Hyalangium minutum].	49.14	291	137	3	3	293	2	281	3e-85	269
rs:WP_026674916	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus bogoriensis].	47.08	291	143	4	1	291	1	280	3e-85	269
rs:WP_019373223	5,10-methylene-tetrahydrofolate dehydrogenase [Alicycliphilus sp. CRZ1].	50.34	294	130	5	1	291	1	281	3e-85	269
tr:A0A093G6G1_PICPB	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFV64718.1}; Flags: Fragment;	50.00	298	142	3	3	294	4	300	3e-85	270
tr:E8QGB4_HELP7	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	3e-85	269
sp:FOLD_PROVI	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.86	290	155	1	5	292	3	292	3e-85	269
rs:WP_000525736	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	3e-85	269
rs:WP_022306270	bifunctional protein FolD [Roseburia sp. CAG:380].	50.00	284	131	3	3	286	2	274	3e-85	269
rs:WP_028623744	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. Ant30-3].	48.28	290	140	2	1	290	1	280	4e-85	269
rs:WP_026719543	5,10-methylene-tetrahydrofolate cyclohydrolase [Fischerella sp. PCC 9431].	46.67	285	146	2	2	286	5	283	4e-85	269
rs:WP_020649838	hypothetical protein [Solimonas variicoloris].	51.68	298	133	4	1	297	1	288	4e-85	269
rs:WP_029147789	methenyltetrahydrofolate cyclohydrolase [Methylophilus sp. 5].	48.26	288	139	2	1	288	1	278	4e-85	269
rs:WP_015326251	5,10-methylene-tetrahydrofolate dehydrogenase [Halobacteroides halobius].	48.78	287	135	3	5	291	8	282	4e-85	269
rs:WP_020800923	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas].	47.59	290	142	2	1	290	1	280	4e-85	269
rs:WP_024858081	5,10-methylene-tetrahydrofolate cyclohydrolase [Ruminococcus albus].	51.90	289	128	4	3	291	2	279	4e-85	269
rs:WP_040936670	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochloron didemni].	48.78	287	140	3	1	286	1	281	4e-85	269
rs:WP_025386003	methenyltetrahydrofolate cyclohydrolase [Legionella oakridgensis].	47.06	289	143	2	1	289	1	279	4e-85	269
rs:WP_016287261	FolD protein [Lachnospiraceae bacterium 3-1].	48.62	290	138	3	3	292	2	280	4e-85	269
rs:WP_043894985	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus lutetiensis].	49.14	291	138	3	3	293	2	282	4e-85	269
rs:WP_035772335	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. VCD2006].	49.65	286	135	2	4	289	2	278	4e-85	269
rs:WP_018621047	5,10-methylene-tetrahydrofolate dehydrogenase [Spirosoma luteum].	43.64	291	164	0	4	294	2	292	4e-85	269
rs:WP_026805296	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Arcobacter].	48.25	286	138	3	5	290	3	278	4e-85	269
rs:WP_015053734	5,10-methylene-tetrahydrofolate dehydrogenase [Methanolobus psychrophilus].	48.94	284	134	3	6	289	11	283	4e-85	269
rs:WP_044464005	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. MRSN12121].	47.93	290	141	2	1	290	1	280	4e-85	269
rs:WP_014718989	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	48.28	290	140	2	1	290	1	280	4e-85	269
tr:R2S2F9_9ENTE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.97	292	138	4	1	292	1	281	4e-85	269
rs:WP_033756381	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	45.49	288	147	2	5	292	8	285	4e-85	269
rs:WP_033903271	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. FH1].	48.62	290	139	2	1	290	1	280	4e-85	269
rs:WP_041319878	methenyltetrahydrofolate cyclohydrolase [Hyphomicrobium denitrificans].	50.68	292	134	2	1	292	1	282	4e-85	269
rs:WP_001133657	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.49	288	147	2	5	292	8	285	4e-85	269
rs:WP_012468592	5,10-methylene-tetrahydrofolate dehydrogenase [Geobacter lovleyi].	50.51	293	132	4	1	292	1	281	4e-85	269
rs:WP_034554197	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter apodemus].	47.74	287	139	4	4	290	2	277	4e-85	269
rs:XP_009874673	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Apaloderma vittatum].	49.66	298	143	3	3	294	3	299	4e-85	269
rs:WP_019783586	tetrahydrofolate dehydrogenase [Streptococcus sobrinus].	48.81	293	140	2	1	293	1	283	4e-85	269
rs:WP_004160794	5,10-methylene-tetrahydrofolate dehydrogenase [Microcystis aeruginosa].	47.95	292	141	2	2	293	5	285	4e-85	269
rs:XP_011023375	PREDICTED: bifunctional protein FolD 4, chloroplastic [Populus euphratica].	48.81	293	144	2	2	292	75	363	4e-85	271
rs:WP_020296823	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. CF161].	47.59	290	142	2	1	290	1	280	4e-85	269
rs:WP_040163898	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	4e-85	269
rs:XP_010411812	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Corvus cornix cornix].	50.34	298	141	3	3	294	84	380	4e-85	272
rs:XP_006288019	hypothetical protein CARUB_v10001252mg [Capsella rubella].	48.97	292	143	2	2	291	67	354	4e-85	271
tr:H0YTI1_TAEGU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTGUP00000001594}; Flags: Fragment;	50.34	298	141	3	3	294	4	300	4e-85	269
tr:A0A091L3G5_CATAU	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFP49843.1}; Flags: Fragment;	50.34	298	141	3	3	294	4	300	4e-85	269
sp:FOLD_SYMTH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.71	292	128	4	1	290	1	281	4e-85	269
rs:WP_015389491	methylenetetrahydrofolate dehydrogenase [Candidatus Kinetoplastibacterium galatii].	48.12	293	141	3	1	293	1	282	4e-85	269
rs:WP_013485539	5,10-methylene-tetrahydrofolate dehydrogenase [Ethanoligenens harbinense].	52.60	289	126	4	1	289	1	278	4e-85	269
rs:WP_022236545	bifunctional protein FolD [Clostridium leptum CAG:27].	52.08	288	127	4	3	290	2	278	4e-85	269
rs:WP_027449499	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella brevis].	49.14	291	147	1	4	294	2	291	4e-85	269
tr:A0A091NT28_APAVI	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFP92247.1}; Flags: Fragment;	49.66	298	143	3	3	294	4	300	4e-85	269
rs:WP_019823166	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. CF149].	48.28	290	140	2	1	290	1	280	4e-85	269
rs:WP_006568916	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Anaerostipes].	48.78	287	136	3	4	290	3	278	4e-85	269
rs:WP_001933829	tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.49	288	147	2	5	292	10	287	4e-85	269
rs:WP_015215279	5,10-methylene-tetrahydrofolate dehydrogenase [Anabaena cylindrica].	49.47	285	138	2	2	286	5	283	4e-85	269
tr:A0A0D6AKF6_9CHRO	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:BAQ62989.1};	48.07	285	142	2	1	285	1	279	4e-85	269
tr:A0A072U119_MEDTR	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:KEH23347.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:KEH23347};	49.31	290	141	2	4	291	57	342	4e-85	271
rs:WP_015734456	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus].	50.87	289	131	4	3	291	4	281	4e-85	269
rs:WP_036104231	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria grayi].	50.52	289	132	4	3	291	2	279	4e-85	269
rs:WP_017294854	hypothetical protein [Geminocystis herdmanii].	48.77	285	140	2	1	285	1	279	4e-85	269
gp:FB505881_1	Sequence 1 from Patent WO2008095972. [Glycine max]	47.95	292	146	2	2	291	50	337	4e-85	271
rs:WP_044274627	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.28	290	140	2	1	290	1	280	4e-85	269
rs:WP_000525704	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	4e-85	269
rs:WP_038982403	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	47.59	290	142	2	1	290	1	280	4e-85	269
rs:WP_000525723	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	4e-85	269
rs:WP_017150887	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus sp. FJAT-13831].	50.00	292	135	4	1	292	1	281	4e-85	269
rs:WP_045202143	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. 2(2015)].	48.28	290	140	2	1	290	1	280	4e-85	269
rs:WP_033122848	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	4e-85	269
rs:WP_017337583	bifunctional protein FolD [Pseudomonas fluorescens].	47.93	290	141	2	1	290	1	280	4e-85	269
rs:WP_045188700	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. 5].	48.45	291	140	2	1	291	1	281	4e-85	269
tr:I9T5B3_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	5e-85	269
rs:WP_019408037	methenyltetrahydrofolate cyclohydrolase [Pseudomonas psychrophila].	48.28	290	140	2	1	290	1	280	5e-85	269
rs:WP_034308293	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus simplex].	47.44	293	143	4	1	293	1	282	5e-85	269
sp:FOLD_HELPH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.14	288	148	2	5	292	8	285	5e-85	269
rs:WP_033009410	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillaceae].	49.83	291	135	4	1	291	1	280	5e-85	269
rs:WP_003192259	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	48.28	290	140	2	1	290	1	280	5e-85	269
rs:WP_018299470	hypothetical protein [Fangia hongkongensis].	47.92	288	140	2	3	290	2	279	5e-85	269
rs:WP_001133654	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	5e-85	269
rs:XP_004492706	PREDICTED: bifunctional protein FolD 4, chloroplastic [Cicer arietinum].	47.95	292	146	2	2	291	59	346	5e-85	271
rs:WP_044057592	methenyltetrahydrofolate cyclohydrolase [Alteromonas australica].	48.80	291	139	2	1	291	1	281	5e-85	268
rs:WP_019271656	methenyltetrahydrofolate cyclohydrolase [Neisseria sicca].	49.13	289	137	2	1	289	1	279	5e-85	268
rs:WP_015372462	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas poae].	48.62	290	139	2	1	290	1	280	5e-85	268
rs:WP_026906649	5,10-methylene-tetrahydrofolate cyclohydrolase [Paucisalibacillus globulus].	46.74	291	144	4	1	291	1	280	5e-85	268
rs:WP_041051187	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	5e-85	269
rs:WP_009004168	5,10-methylene-tetrahydrofolate dehydrogenase [Clostridium sp. D5].	50.52	289	132	4	3	291	2	279	5e-85	268
tr:T5D390_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.83	288	146	2	5	292	8	285	5e-85	269
rs:WP_027340055	5,10-methylene-tetrahydrofolate cyclohydrolase [Halonatronum saccharophilum].	48.26	288	137	3	4	291	7	282	5e-85	269
rs:WP_028874739	methenyltetrahydrofolate cyclohydrolase [Tepidiphilus margaritifer].	50.52	291	132	4	1	291	1	279	5e-85	269
tr:A0A031GAD0_9PSED	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.93	290	141	2	1	290	1	280	5e-85	268
rs:WP_043048708	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.28	290	140	2	1	290	1	280	5e-85	268
rs:WP_016978014	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.62	290	139	2	1	290	1	280	5e-85	268
rs:WP_017777976	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia kururiensis].	48.97	292	138	3	1	292	1	281	5e-85	268
rs:WP_022113392	bifunctional protein FolD [Clostridium sp. CAG:245].	48.10	289	139	4	4	292	3	280	5e-85	268
rs:WP_008681482	tetrahydrofolate dehydrogenase [Rhodopirellula sallentina].	47.84	301	139	3	1	290	1	294	5e-85	269
rs:WP_002122426	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus].	49.66	292	136	4	1	292	1	281	5e-85	269
rs:WP_025335723	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sabinae].	49.83	291	135	3	1	291	1	280	5e-85	268
rs:WP_026839933	5,10-methylene-tetrahydrofolate cyclohydrolase [Geobacter bremensis].	48.11	291	140	3	3	293	2	281	5e-85	268
rs:WP_044647652	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus terrae].	49.66	292	136	4	1	292	1	281	5e-85	268
rs:WP_029517261	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus polymyxa].	49.66	292	136	4	1	292	1	281	5e-85	268
sp:FOLD_POLNA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.97	292	138	4	1	292	1	281	5e-85	268
rs:WP_033619033	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	5e-85	269
rs:WP_043682459	methenyltetrahydrofolate cyclohydrolase [Castellaniella defragrans].	49.83	293	136	4	1	293	1	282	5e-85	268
rs:WP_015429071	methylenetetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	5e-85	269
tr:E6QQJ1_9ZZZZ	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase and 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:CBI09512.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CBI09512.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CBI09512.1};	51.03	292	133	2	1	292	1	282	5e-85	269
rs:WP_024327111	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio sp. AKL19].	49.31	288	136	2	1	288	1	278	5e-85	269
rs:WP_044910438	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium MC2017].	51.04	288	132	3	3	290	2	280	5e-85	268
rs:WP_000525737	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	5e-85	269
rs:WP_000525731	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	5e-85	269
rs:WP_000062601	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.83	288	146	2	5	292	10	287	5e-85	269
tr:J0C581_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.14	288	148	2	5	292	8	285	5e-85	269
rs:WP_001133662	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.49	288	147	2	5	292	8	285	5e-85	269
rs:WP_004883900	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas viridiflava].	48.28	290	140	2	1	290	1	280	5e-85	268
rs:WP_039856158	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Neisseria].	49.13	289	137	2	1	289	1	279	5e-85	268
tr:J0JAU0_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	5e-85	269
rs:WP_046560738	methenyltetrahydrofolate cyclohydrolase [Kangiella geojedonensis].	49.31	290	137	3	1	290	1	280	5e-85	268
rs:WP_000071059	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	5e-85	269
rs:XP_008927548	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Manacus vitellinus].	51.01	298	139	3	3	294	130	426	5e-85	273
rs:XP_011091895	PREDICTED: bifunctional protein FolD 4, chloroplastic [Sesamum indicum].	48.81	295	143	3	2	292	74	364	5e-85	271
sp:FOLD_PSEF5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.93	290	141	2	1	290	1	280	5e-85	268
rs:WP_044158030	5,10-methylene-tetrahydrofolate cyclohydrolase [Salinibacillus aidingensis].	48.11	291	140	3	1	291	1	280	5e-85	268
tr:A0A072U2F8_MEDTR	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:KEH23348.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:KEH23348};	49.31	290	141	2	4	291	78	363	5e-85	271
sp:FOLD_HELAH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	10	287	5e-85	269
rs:WP_046737224	methenyltetrahydrofolate cyclohydrolase [Dehalogenimonas sp. WBC-2].	45.86	290	156	1	1	290	1	289	5e-85	269
rs:WP_017255137	methenyltetrahydrofolate cyclohydrolase [Pseudomonas tolaasii].	48.28	290	140	2	1	290	1	280	5e-85	268
rs:WP_009517576	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Hydrogenophaga].	48.97	292	138	3	1	292	1	281	5e-85	268
rs:WP_023845092	5,10-methylene-tetrahydrofolate dehydrogenase [Methanolobus tindarius].	48.59	284	135	2	6	289	11	283	5e-85	268
rs:WP_044785230	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus polymyxa].	49.66	292	136	4	1	292	1	281	5e-85	268
rs:XP_007218182	hypothetical protein PRUPE_ppa007647mg [Prunus persica].	48.11	291	145	2	3	291	69	355	6e-85	271
rs:WP_046542804	5,10-methylene-tetrahydrofolate cyclohydrolase [Trichodesmium thiebautii].	48.04	281	140	2	6	286	5	279	6e-85	268
rs:WP_001133665	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	6e-85	268
rs:WP_028639591	methenyltetrahydrofolate cyclohydrolase [Novosphingobium acidiphilum].	49.83	293	136	3	1	293	1	282	6e-85	268
rs:XP_010427264	PREDICTED: bifunctional protein FolD 4, chloroplastic-like isoform X1 [Camelina sativa].	48.29	292	145	2	2	291	67	354	6e-85	271
rs:WP_041908521	5,10-methylene-tetrahydrofolate cyclohydrolase [Candidatus Iainarchaeum andersonii].	48.45	291	139	3	1	291	1	280	6e-85	268
rs:WP_003174824	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	47.93	290	141	2	1	290	1	280	6e-85	268
rs:WP_022443835	bifunctional protein FolD 2 [Sutterella sp. CAG:351].	50.52	289	133	3	1	289	1	279	6e-85	268
rs:WP_033601987	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	6e-85	269
rs:WP_001133666	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	46.18	288	145	2	5	292	8	285	6e-85	268
tr:Q2PES9_TRIPR	SubName: Full=Putative tetrahydrofolate synthase {ECO:0000313|EMBL:BAE71273.1};	49.14	291	142	2	3	291	59	345	6e-85	271
rs:XP_009096768	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Serinus canaria].	50.34	298	141	3	3	294	51	347	6e-85	270
rs:WP_040208161	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus].	48.81	293	139	4	1	293	1	282	6e-85	268
rs:WP_023079898	tetrahydrofolate dehydrogenase [Streptococcus pyogenes].	47.42	291	143	2	4	294	3	283	6e-85	268
rs:WP_043996279	5,10-methylene-tetrahydrofolate cyclohydrolase [Microcystis aeruginosa].	47.95	292	141	2	2	293	5	285	6e-85	268
rs:WP_034134302	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.28	290	140	2	1	290	1	280	6e-85	268
rs:WP_021083622	methylenetetrahydrofolate dehydrogenase [Campylobacter concisus].	51.72	290	129	4	4	293	2	280	6e-85	268
rs:WP_047334214	5,10-methylene-tetrahydrofolate cyclohydrolase [Enterococcus cecorum].	49.83	287	133	4	5	291	3	278	6e-85	268
rs:WP_001133637	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	8	285	6e-85	268
rs:WP_017134092	methenyltetrahydrofolate cyclohydrolase [Pseudomonas agarici].	47.59	290	142	2	1	290	1	280	6e-85	268
rs:WP_022261880	bifunctional protein FolD [Butyrivibrio sp. CAG:318].	50.88	285	132	4	3	286	2	279	7e-85	268
rs:WP_008089453	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	47.42	291	143	2	1	291	1	281	7e-85	268
rs:WP_015041559	methylenetetrahydrofolate dehydrogenase [Bordetella bronchiseptica].	48.29	292	140	3	1	292	1	281	7e-85	268
sp:FOLD_CAMC5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.57	287	128	4	4	290	2	277	7e-85	268
rs:WP_002173408	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus].	49.66	292	136	4	1	292	1	281	7e-85	268
rs:WP_015884725	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.28	290	140	2	1	290	1	280	7e-85	268
rs:WP_016822287	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus].	49.66	292	136	4	1	292	1	281	7e-85	268
rs:WP_028204188	methenyltetrahydrofolate cyclohydrolase [Burkholderia nodosa].	48.97	292	138	3	1	292	1	281	7e-85	268
rs:WP_000525733	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	7e-85	268
rs:WP_024113918	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.83	288	146	2	5	292	8	285	7e-85	268
rs:WP_015644999	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	7e-85	268
rs:WP_044744473	5,10-methylene-tetrahydrofolate cyclohydrolase [Anoxybacillus sp. ATCC BAA-2555].	48.45	291	139	4	1	291	1	280	7e-85	268
rs:XP_005531799	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Pseudopodoces humilis].	50.34	298	141	3	3	294	50	346	7e-85	270
rs:WP_002199388	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus].	49.32	292	137	4	1	292	1	281	7e-85	268
tr:A0A0B2R716_GLYSO	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:KHN29380.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KHN29380.1}; EC=3.5.4.9 {ECO:0000313|EMBL:KHN29380.1};	47.60	292	147	2	2	291	17	304	7e-85	269
rs:WP_015837980	5,10-methylene-tetrahydrofolate dehydrogenase [Geobacter sp. M21].	48.11	291	140	3	3	293	2	281	7e-85	268
rs:WP_033615945	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	7e-85	268
rs:XP_010419615	PREDICTED: bifunctional protein FolD 4, chloroplastic-like isoform X2 [Camelina sativa].	48.29	292	145	2	2	291	68	355	7e-85	271
rs:WP_038362797	bifunctional protein FolD [Pseudomonas chlororaphis].	48.28	290	140	2	1	290	1	280	7e-85	268
rs:WP_038314700	methenyltetrahydrofolate cyclohydrolase [Kingella kingae].	48.97	290	138	2	1	290	1	280	7e-85	268
rs:WP_024116260	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	7e-85	268
rs:WP_025871414	methenyltetrahydrofolate cyclohydrolase [Methylobacillus glycogenes].	46.88	288	143	2	1	288	1	278	7e-85	268
rs:WP_002748060	methenyltetrahydrofolate cyclohydrolase [Microcystis aeruginosa].	47.95	292	141	2	2	293	5	285	7e-85	268
rs:WP_025165699	methenyltetrahydrofolate cyclohydrolase [Pseudomonas taeanensis].	50.00	290	135	2	1	290	1	280	7e-85	268
rs:WP_036006071	5,10-methylene-tetrahydrofolate cyclohydrolase [Leptolyngbya sp. JSC-1].	48.43	287	143	2	5	291	4	285	7e-85	268
rs:WP_021857937	bifunctional protein FolD [Firmicutes bacterium CAG:83].	49.83	291	132	4	1	291	1	277	7e-85	268
rs:WP_033782411	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	7e-85	268
rs:XP_010789042	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Notothenia coriiceps].	50.34	294	139	3	3	290	30	322	7e-85	270
rs:WP_046032567	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	47.59	290	142	2	1	290	1	280	7e-85	268
sp:FOLD_BACAH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.66	292	136	4	1	292	1	281	7e-85	268
rs:XP_012757529	hypothetical protein SAMD00019534_014840 [Acytostelium subglobosum LB1].	48.97	292	136	3	2	291	15	295	7e-85	269
rs:WP_000226719	bifunctional protein FolD [Bacillus cereus].	49.66	292	136	4	1	292	1	281	7e-85	268
rs:WP_004298184	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Thauera].	48.63	292	143	3	1	292	1	285	7e-85	268
tr:K1ZN46_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.79	289	138	2	5	293	4	282	7e-85	268
rs:WP_025108912	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. H1h].	47.93	290	141	2	1	290	1	280	7e-85	268
rs:WP_009853129	methenyltetrahydrofolate cyclohydrolase [beta proteobacterium KB13].	47.78	293	142	2	1	293	1	282	7e-85	268
tr:N0B8F9_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.68	292	134	2	1	292	14	295	7e-85	269
rs:WP_001938019	tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	7e-85	268
rs:XP_001846733	bifunctional protein folD [Culex quinquefasciatus].	47.08	291	150	3	3	290	2	291	7e-85	269
rs:WP_024422033	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	8e-85	268
rs:WP_014294173	tetrahydrofolate dehydrogenase [Streptococcus macedonicus].	49.48	291	137	2	3	293	2	282	8e-85	268
rs:WP_007917331	MULTISPECIES: bifunctional protein FolD [Pseudomonas].	48.28	290	140	2	1	290	1	280	8e-85	268
rs:WP_029321494	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. AE3004].	48.44	289	140	3	5	293	3	282	8e-85	268
rs:WP_027906791	methenyltetrahydrofolate cyclohydrolase [Pseudomonas taiwanensis].	47.42	291	143	2	1	291	1	281	8e-85	268
rs:WP_008844206	methenyltetrahydrofolate cyclohydrolase [Aliiglaciecola lipolytica].	49.14	291	138	2	1	291	1	281	8e-85	268
rs:WP_013032004	methenyltetrahydrofolate cyclohydrolase [Nitrosococcus halophilus].	48.80	291	139	2	1	291	1	281	8e-85	268
rs:WP_038613050	methenyltetrahydrofolate cyclohydrolase [Pseudomonas alkylphenolia].	48.11	291	141	2	1	291	1	281	8e-85	268
rs:WP_022837048	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Marinimicrobia].	47.78	293	152	1	1	293	1	292	8e-85	268
rs:WP_001133634	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	8e-85	268
tr:A0A0A4GG17_9PSED	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.24	290	143	2	1	290	1	280	8e-85	268
rs:WP_032896515	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. Eur1 9.41].	48.28	290	140	2	1	290	1	280	8e-85	268
rs:WP_037285540	5,10-methylene-tetrahydrofolate cyclohydrolase [Ruminococcus albus].	51.90	289	128	4	3	291	2	279	8e-85	268
tr:J0NAJ1_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	8e-85	268
rs:WP_038417497	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	8e-85	268
rs:WP_040063128	methenyltetrahydrofolate cyclohydrolase [Pseudomonas batumici].	47.24	290	143	2	1	290	1	280	8e-85	268
rs:WP_039086232	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	8e-85	268
rs:XP_008141902	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Eptesicus fuscus].	49.66	298	143	3	3	294	40	336	8e-85	270
tr:A0A098FIQ9_9BACI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.60	292	142	4	1	292	1	281	8e-85	268
rs:WP_002111753	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus].	49.32	292	137	4	1	292	1	281	8e-85	268
sp:FOLD_POLSQ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.81	295	140	3	1	295	1	284	8e-85	268
rs:WP_036911186	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella sp. FD3004].	49.14	291	147	1	4	294	2	291	8e-85	268
rs:XP_005874876	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Myotis brandtii].	49.66	298	143	3	3	294	34	330	8e-85	270
rs:WP_041013952	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri group].	47.93	290	141	2	1	290	1	280	8e-85	268
rs:WP_002160530	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus].	49.32	292	137	4	1	292	1	281	8e-85	268
rs:WP_042138732	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. FSL P4-0081].	48.80	291	138	4	1	291	1	280	8e-85	268
rs:WP_033465057	methenyltetrahydrofolate cyclohydrolase [Bordetella bronchiseptica].	48.29	292	140	3	1	292	1	281	8e-85	268
rs:WP_001879865	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	8e-85	268
sp:FOLD_MICAN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.95	292	141	2	2	293	5	285	8e-85	268
rs:WP_017727017	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus ligniniphilus].	50.86	291	131	3	1	291	1	279	8e-85	268
rs:WP_025222724	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	8e-85	268
rs:WP_008367812	5,10-methylene-tetrahydrofolate dehydrogenase [Halorubrum litoreum].	51.22	287	136	4	4	289	3	286	8e-85	268
rs:WP_044882109	methenyltetrahydrofolate cyclohydrolase [Neochlamydia sp. EPS4].	46.55	290	151	2	5	293	2	288	8e-85	268
rs:WP_036698383	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus].	48.11	291	140	4	1	291	1	280	8e-85	268
rs:WP_016859660	methenyltetrahydrofolate cyclohydrolase [Fischerella muscicola].	47.02	285	145	2	2	286	5	283	9e-85	268
rs:WP_017282568	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	9e-85	268
rs:WP_043633000	methenyltetrahydrofolate cyclohydrolase [Desulfovibrio sp. TomC].	51.40	286	133	1	5	290	3	282	9e-85	268
tr:A0A061INB2_CRIGR	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:ERE90859.1}; EC=3.5.4.9 {ECO:0000313|EMBL:ERE90859.1};	50.00	298	142	3	3	294	42	338	9e-85	270
rs:WP_029054562	5,10-methylene-tetrahydrofolate cyclohydrolase [Sporosarcina ureae].	46.76	293	145	4	1	293	1	282	9e-85	268
sp:FOLD_SORC5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.60	294	146	3	1	293	1	284	9e-85	268
rs:WP_016986882	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.28	290	140	2	1	290	1	280	9e-85	268
rs:WP_000226730	bifunctional protein FolD [Bacillus cereus].	50.00	292	135	4	1	292	1	281	9e-85	268
sp:FOLD_LISIN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.83	289	134	4	3	291	2	279	9e-85	268
rs:WP_040498830	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter winghamensis].	47.59	290	141	3	4	293	2	280	9e-85	268
tr:J0UE24_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.14	288	148	2	5	292	8	285	9e-85	268
rs:WP_036073336	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria aquatica].	50.17	291	134	4	3	293	2	281	9e-85	268
tr:G3ADR2_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.08	291	144	2	1	291	1	281	9e-85	268
rs:WP_016974099	methenyltetrahydrofolate cyclohydrolase [Pseudomonas tolaasii].	48.62	290	139	2	1	290	1	280	9e-85	268
rs:WP_003766782	5,10-methylene-tetrahydrofolate dehydrogenase [Listeria innocua].	49.83	289	134	4	3	291	2	279	9e-85	268
rs:WP_046619372	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	47.93	290	141	2	1	290	1	280	9e-85	268
rs:XP_002872936	hypothetical protein ARALYDRAFT_490506 [Arabidopsis lyrata subsp. lyrata].	48.45	291	144	2	3	291	70	356	9e-85	270
tr:C3XNW8_9HELI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.59	290	141	3	4	293	3	281	9e-85	268
rs:WP_027925381	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. URMO17WK12:I12].	47.59	290	142	2	1	290	1	280	9e-85	268
tr:M3RXU2_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.14	288	148	2	5	292	10	287	9e-85	268
rs:WP_027185937	methenyltetrahydrofolate cyclohydrolase [Desulfovibrio inopinatus].	48.44	289	142	2	5	293	3	284	9e-85	268
rs:WP_009332895	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus].	47.97	296	143	3	1	296	1	285	9e-85	268
rs:WP_008385326	5,10-methylene-tetrahydrofolate dehydrogenase [Halogeometricum pallidum].	48.96	288	139	3	5	289	4	286	9e-85	268
rs:WP_000226735	MULTISPECIES: bifunctional protein FolD [Bacillus cereus group].	50.00	292	135	4	1	292	1	281	9e-85	268
rs:WP_037579081	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus equi].	47.93	290	141	2	4	293	3	282	9e-85	268
rs:XP_010456258	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X1 [Camelina sativa].	48.45	291	144	2	3	291	68	354	9e-85	270
sp:FOLD1_BORPA	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.29	292	140	3	1	292	1	281	9e-85	268
rs:WP_000525724	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	9e-85	268
rs:WP_046574351	5,10-methylene-tetrahydrofolate cyclohydrolase [Spirosoma radiotolerans].	44.33	291	162	0	4	294	2	292	1e-84	268
rs:WP_039576569	methenyltetrahydrofolate cyclohydrolase [Pseudomonas parafulva].	47.42	291	143	2	1	291	1	281	1e-84	268
rs:WP_031492375	methenyltetrahydrofolate cyclohydrolase [Succinivibrio dextrinosolvens].	50.34	290	129	5	1	286	1	279	1e-84	268
rs:WP_013310816	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus polymyxa].	49.66	292	136	4	1	292	1	281	1e-84	268
rs:WP_029241486	methenyltetrahydrofolate cyclohydrolase [Pseudomonas viridiflava].	48.28	290	140	2	1	290	1	280	1e-84	268
rs:WP_023379632	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. VLB120].	47.42	291	143	2	1	291	1	281	1e-84	268
rs:WP_022165803	bifunctional protein FolD [Eubacterium sp. CAG:192].	50.35	284	130	4	3	286	2	274	1e-84	268
tr:A0A061NH23_9BACL	RecName: Full=N utilization substance protein B homolog {ECO:0000256|SAAS:SAAS00057003};	49.31	290	136	3	1	290	137	415	1e-84	272
rs:WP_000226736	bifunctional protein FolD [Bacillus cereus].	50.00	292	135	4	1	292	1	281	1e-84	268
rs:WP_004275244	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter upsaliensis].	50.00	290	132	4	5	293	3	280	1e-84	268
tr:E8QVS2_HELPW	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	1e-84	268
rs:WP_001919756	bifunctional protein FolD [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	1e-84	268
rs:WP_018973252	hypothetical protein [Rudaea cellulosilytica].	48.97	292	139	2	1	292	1	282	1e-84	268
rs:WP_026938370	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	1e-84	268
sp:FOLD_STREM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.93	290	141	2	4	293	3	282	1e-84	268
rs:WP_039753056	5,10-methylene-tetrahydrofolate cyclohydrolase [Hassallia byssoidea].	48.07	285	142	2	2	286	5	283	1e-84	268
rs:WP_039385223	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Neochlamydia].	46.55	290	151	2	5	293	2	288	1e-84	268
rs:WP_027099974	methenyltetrahydrofolate cyclohydrolase [Comamonadaceae bacterium URHA0028].	48.63	292	139	3	1	292	1	281	1e-84	268
rs:WP_038318978	methenyltetrahydrofolate cyclohydrolase [Kingella kingae].	48.97	290	138	2	1	290	1	280	1e-84	268
rs:WP_000525728	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	1e-84	268
rs:WP_025722628	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus polymyxa].	49.66	292	136	4	1	292	1	281	1e-84	268
rs:WP_038441822	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.28	290	140	2	1	290	1	280	1e-84	268
rs:WP_042355095	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. MT2].	49.32	294	138	4	1	294	1	283	1e-84	268
rs:WP_025846926	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus ehimensis].	48.97	292	138	4	1	292	1	281	1e-84	268
rs:WP_037625927	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus uberis].	47.93	290	141	2	4	293	3	282	1e-84	268
rs:XP_005681999	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Capra hircus].	50.00	298	142	3	3	294	105	401	1e-84	271
rs:WP_025150069	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. H1a].	49.66	292	136	4	1	292	1	281	1e-84	268
rs:WP_025996883	methenyltetrahydrofolate cyclohydrolase [Pseudomonas viridiflava].	48.28	290	140	2	1	290	1	280	1e-84	268
rs:WP_003103748	tetrahydrofolate dehydrogenase [Streptococcus parauberis].	48.97	290	138	2	4	293	3	282	1e-84	268
rs:WP_028883679	methenyltetrahydrofolate cyclohydrolase [Taylorella asinigenitalis].	49.13	289	136	3	3	291	2	279	1e-84	268
rs:XP_010134692	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Buceros rhinoceros silvestris].	49.66	298	143	3	3	294	3	299	1e-84	268
rs:WP_043932826	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. EB01].	47.26	292	143	4	1	292	1	281	1e-84	268
rs:WP_000525740	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	1e-84	268
rs:WP_017283825	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	1e-84	268
rs:WP_042207466	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus durus].	49.48	291	136	3	1	291	1	280	1e-84	268
rs:WP_033603215	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	1e-84	268
rs:WP_017715636	hypothetical protein [Oscillatoria sp. PCC 10802].	47.72	285	143	2	2	286	5	283	1e-84	268
rs:WP_033588159	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	1e-84	268
rs:WP_001133988	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	1e-84	268
rs:WP_007047070	5,10-methylene-tetrahydrofolate dehydrogenase [Subdoligranulum variabile].	47.10	293	144	3	1	293	1	282	1e-84	268
rs:WP_006002647	methenyltetrahydrofolate cyclohydrolase [Glaciecola punicea].	47.92	288	140	2	1	288	1	278	1e-84	268
tr:A0A091H216_BUCRH	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFO89876.1}; Flags: Fragment;	49.66	298	143	3	3	294	4	300	1e-84	268
rs:WP_041059175	5,10-methylene-tetrahydrofolate cyclohydrolase [Jeotgalibacillus campisalis].	48.81	293	139	4	1	293	1	282	1e-84	268
rs:WP_038996170	methenyltetrahydrofolate cyclohydrolase [Pseudomonas putida].	48.11	291	141	2	1	291	1	281	1e-84	268
rs:WP_023592131	methenyltetrahydrofolate cyclohydrolase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	1e-84	268
rs:WP_031248067	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	1e-84	268
rs:WP_039763375	bifunctional protein FolD [Pseudomonas fluorescens].	47.93	290	141	2	1	290	1	280	1e-84	268
rs:WP_007901791	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	47.59	290	142	2	1	290	1	280	1e-84	268
rs:WP_018715645	5,10-methylene-tetrahydrofolate dehydrogenase [Brachymonas chironomi].	48.97	292	138	4	1	292	1	281	1e-84	268
rs:WP_031484712	methenyltetrahydrofolate cyclohydrolase [Desulfovibrio frigidus].	47.75	289	144	2	5	293	3	284	1e-84	268
rs:XP_012454448	PREDICTED: bifunctional protein FolD 4, chloroplastic-like isoform X3 [Gossypium raimondii].	48.12	293	146	2	2	292	70	358	1e-84	270
sp:FOLD_NEIG1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.13	289	137	2	1	289	1	279	1e-84	268
rs:WP_000525725	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	1e-84	268
tr:E1PZ35_HELPM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.14	288	148	2	5	292	8	285	1e-84	268
tr:X2IJC7_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	15	292	1e-84	268
rs:WP_002996854	tetrahydrofolate dehydrogenase [Streptococcus downei].	48.46	293	141	2	1	293	1	283	1e-84	268
rs:WP_014098063	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus coagulans].	48.11	291	140	3	1	291	1	280	1e-84	268
rs:WP_002735754	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Microcystis].	47.95	292	141	2	2	293	5	285	1e-84	268
rs:XP_002000379	GI10194 [Drosophila mojavensis].	46.96	296	149	3	3	292	2	295	1e-84	268
rs:WP_026939706	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	1e-84	268
rs:WP_023526046	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	1e-84	268
rs:WP_029132151	methenyltetrahydrofolate cyclohydrolase [Sedimenticola selenatireducens].	48.26	288	139	2	1	288	1	278	1e-84	268
rs:WP_007585776	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia terrae].	51.55	291	130	3	1	291	1	280	1e-84	268
rs:WP_008010063	5,10-methylene-tetrahydrofolate dehydrogenase [Haloterrigena limicola].	48.25	286	146	2	4	289	3	286	1e-84	268
rs:WP_032860284	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. FH4].	48.62	290	139	2	1	290	1	280	1e-84	268
rs:WP_007277089	5,10-methylene-tetrahydrofolate dehydrogenase [Lentisphaera araneosa].	47.95	292	149	2	1	291	1	290	1e-84	268
rs:WP_017430319	methenyltetrahydrofolate cyclohydrolase [Halomonas jeotgali].	48.62	290	139	2	1	290	1	280	1e-84	268
rs:WP_042979794	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus mycoides].	49.66	292	136	4	1	292	1	281	1e-84	268
rs:WP_039082551	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	1e-84	268
rs:WP_033603874	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	1e-84	268
rs:WP_041090231	5,10-methylene-tetrahydrofolate cyclohydrolase [Jeotgalibacillus soli Cunha et al. 2012].	48.12	293	141	4	1	293	1	282	1e-84	268
rs:WP_039838519	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sonchi].	48.45	291	139	3	1	291	1	280	1e-84	268
rs:WP_034810599	5,10-methylene-tetrahydrofolate cyclohydrolase [Enterococcus asini].	48.97	290	137	4	3	292	2	280	1e-84	267
rs:WP_000226740	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus].	49.32	292	137	4	1	292	1	281	1e-84	268
rs:WP_047235757	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus pyogenes].	47.08	291	144	2	4	294	3	283	1e-84	267
tr:T1U999_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	1e-84	268
rs:WP_000226721	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus group].	49.83	291	135	4	1	291	1	280	1e-84	268
rs:WP_033448683	methenyltetrahydrofolate cyclohydrolase [Bordetella bronchiseptica].	48.29	292	140	3	1	292	1	281	1e-84	267
tr:C7C044_HELPB	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	8	285	1e-84	268
rs:WP_039739971	5,10-methylene-tetrahydrofolate cyclohydrolase [Geobacter pickeringii].	48.29	292	143	3	4	293	2	287	1e-84	268
rs:WP_035161156	5,10-methylene-tetrahydrofolate cyclohydrolase [Caloranaerobacter azorensis].	47.42	291	142	2	1	291	1	280	1e-84	268
rs:WP_016183308	tetrahydrofolate dehydrogenase [Enterococcus columbae].	48.61	288	137	3	4	291	3	279	1e-84	267
rs:WP_002067081	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus group].	49.66	292	136	4	1	292	1	281	1e-84	268
tr:A0A099VRJ8_9HELI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.04	287	141	3	4	290	2	277	1e-84	267
rs:WP_033741714	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	1e-84	268
rs:XP_002192217	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Taeniopygia guttata].	50.34	298	141	3	3	294	50	346	1e-84	270
rs:WP_044314724	methenyltetrahydrofolate cyclohydrolase [Pseudomonas stutzeri].	47.93	290	141	2	1	290	1	280	1e-84	267
sp:FOLD_BACC4	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.66	292	136	4	1	292	1	281	1e-84	267
rs:XP_007051872	Amino acid dehydrogenase family protein [Theobroma cacao].	47.78	293	147	2	2	292	70	358	1e-84	270
rs:XP_012454447	PREDICTED: bifunctional protein FolD 4, chloroplastic-like isoform X2 [Gossypium raimondii].	48.12	293	146	2	2	292	70	358	1e-84	270
rs:WP_016322163	hypothetical protein [Oscillibacter sp. 1-3].	50.70	284	126	3	6	289	5	274	1e-84	267
rs:WP_001133661	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	1e-84	268
rs:WP_008073092	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. GM79].	47.24	290	143	2	1	290	1	280	1e-84	267
rs:WP_000525727	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	1e-84	268
rs:WP_014535198	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	1e-84	268
rs:WP_047338695	5,10-methylene-tetrahydrofolate cyclohydrolase [Enterococcus cecorum].	49.83	287	133	4	5	291	3	278	1e-84	267
tr:U4RAY5_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	15	292	1e-84	268
rs:WP_020426562	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus riograndensis].	48.45	291	139	3	1	291	1	280	1e-84	267
rs:WP_002138286	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus].	49.66	292	136	4	1	292	1	281	1e-84	267
rs:WP_034962636	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter hyointestinalis].	49.65	288	134	4	4	291	2	278	1e-84	267
rs:WP_026631519	5,10-methylene-tetrahydrofolate cyclohydrolase [Dyadobacter alkalitolerans].	44.33	291	162	0	4	294	2	292	1e-84	268
rs:WP_038087533	methenyltetrahydrofolate cyclohydrolase [Thiobacillus prosperus].	48.26	288	139	2	1	288	1	278	2e-84	267
rs:XP_002533811	methylenetetrahydrofolate dehydrogenase, putative [Ricinus communis].	48.11	291	145	2	3	291	75	361	2e-84	270
rs:WP_016775338	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	47.93	290	141	2	1	290	1	280	2e-84	267
rs:WP_047242355	5,10-methylene-tetrahydrofolate cyclohydrolase [Enterococcus cecorum].	49.83	287	133	4	5	291	3	278	2e-84	267
rs:WP_000226737	bifunctional protein FolD [Bacillus cereus].	50.00	292	135	4	1	292	1	281	2e-84	267
rs:XP_003290521	methenyl tetrahydrofolate cyclohydrolase [Dictyostelium purpureum].	47.96	294	141	4	3	294	9	292	2e-84	268
rs:WP_039043839	5,10-methylene-tetrahydrofolate cyclohydrolase [Sporosarcina sp. ZBG7A].	49.31	290	136	4	1	290	1	279	2e-84	267
rs:WP_026683280	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus coagulans].	48.11	291	140	3	1	291	1	280	2e-84	267
tr:I4G2F6_MICAE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.95	292	141	2	2	293	18	298	2e-84	268
rs:WP_021746246	tetrahydrofolate dehydrogenase [Leptotrichia wadei].	48.28	290	138	3	5	293	3	281	2e-84	267
rs:WP_028945313	methenyltetrahydrofolate cyclohydrolase [Pseudomonas vranovensis].	48.45	291	140	2	1	291	1	281	2e-84	267
rs:WP_041200567	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	2e-84	268
rs:WP_036690259	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. MSt1].	48.63	292	139	4	1	292	1	281	2e-84	267
rs:WP_046489133	methenyltetrahydrofolate cyclohydrolase [Methylophilaceae bacterium MMS-2-53].	48.29	292	141	3	1	292	1	282	2e-84	267
rs:WP_023079370	tetrahydrofolate dehydrogenase [Streptococcus pyogenes].	47.08	291	144	2	4	294	3	283	2e-84	267
tr:W0RKL2_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.39	287	147	3	1	286	1	284	2e-84	268
rs:WP_022494265	bifunctional protein FolD [Ruminococcus sp. CAG:624].	46.90	290	144	3	3	292	2	281	2e-84	267
tr:A8YM66_MICAE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.95	292	141	2	2	293	18	298	2e-84	268
rs:WP_045359588	5,10-methylene-tetrahydrofolate cyclohydrolase [Microcystis aeruginosa].	47.95	292	141	2	2	293	5	285	2e-84	267
rs:WP_045106235	methenyltetrahydrofolate cyclohydrolase [Legionella hackeliae].	46.55	290	145	2	1	290	1	280	2e-84	267
rs:WP_026779923	methenyltetrahydrofolate cyclohydrolase [Polaromonas sp. EUR3 1.2.1].	48.45	291	139	4	1	291	1	280	2e-84	267
rs:XP_006993589	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Peromyscus maniculatus bairdii].	49.66	298	143	3	3	294	9	305	2e-84	268
rs:WP_027407745	5,10-methylene-tetrahydrofolate cyclohydrolase [Anoxybacillus tepidamans].	47.77	291	141	4	1	291	1	280	2e-84	267
sp:FOLD2_GEOMG	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.26	288	138	3	5	292	4	280	2e-84	267
tr:N4TTU5_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	2e-84	267
rs:WP_001133656	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.83	288	146	2	5	292	8	285	2e-84	267
rs:WP_024117121	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	2e-84	267
rs:WP_009225787	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus sp. oral taxon 786].	49.48	291	136	3	1	291	1	280	2e-84	267
rs:WP_027401935	5,10-methylene-tetrahydrofolate cyclohydrolase [Aphanizomenon flos-aquae].	47.72	285	143	2	2	286	4	282	2e-84	267
rs:WP_033586822	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	2e-84	267
rs:WP_006511453	5,10-methylene-tetrahydrofolate dehydrogenase [Xenococcus sp. PCC 7305].	48.25	286	141	2	3	288	6	284	2e-84	267
rs:WP_041975283	hypothetical protein [Pyrinomonas methylaliphatogenes].	46.08	306	144	2	3	291	9	310	2e-84	268
rs:WP_013233470	5,10-methylene-tetrahydrofolate dehydrogenase [Herbaspirillum seropedicae].	48.45	291	139	3	1	291	1	280	2e-84	267
rs:XP_009355330	PREDICTED: LOW QUALITY PROTEIN: bifunctional protein FolD 4, chloroplastic-like [Pyrus x bretschneideri].	48.45	291	144	2	3	291	72	358	2e-84	270
rs:WP_021310369	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	2e-84	267
rs:WP_024775970	5,10-methylene-tetrahydrofolate cyclohydrolase [Arcobacter cibarius].	47.20	286	141	3	5	290	3	278	2e-84	267
rs:WP_024117703	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	2e-84	267
rs:WP_027265714	methenyltetrahydrofolate cyclohydrolase [Legionella pneumophila].	46.39	291	146	2	1	291	1	281	2e-84	267
rs:WP_013783302	methenyltetrahydrofolate cyclohydrolase [Alteromonas sp. SN2].	48.80	291	139	2	1	291	1	281	2e-84	267
rs:WP_015427740	methylenetetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	2e-84	267
rs:WP_025707026	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus graminis].	48.45	291	139	3	1	291	1	280	2e-84	267
rs:WP_042559951	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	47.59	290	142	2	1	290	1	280	2e-84	267
rs:WP_041021203	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. SHC52].	47.59	290	142	2	1	290	1	280	2e-84	267
rs:WP_033615108	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	2e-84	267
rs:NP_001239795	uncharacterized protein LOC100819231 [Glycine max].	47.60	292	147	2	2	291	53	340	2e-84	269
rs:WP_005870570	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter gracilis].	49.31	290	135	4	5	293	3	281	2e-84	267
tr:I9VQ39_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.14	288	148	2	5	292	8	285	2e-84	267
rs:WP_029298425	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.62	290	139	2	1	290	1	280	2e-84	267
rs:WP_016251179	tetrahydrofolate dehydrogenase [Enterococcus cecorum].	49.83	287	133	4	5	291	3	278	2e-84	267
rs:WP_000525702	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	2e-84	267
rs:WP_001867947	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	2e-84	267
rs:WP_003200229	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus].	49.66	292	136	4	1	292	1	281	2e-84	267
rs:WP_007996909	5,10-methylene-tetrahydrofolate dehydrogenase [Halorubrum arcis].	50.87	287	137	4	4	289	3	286	2e-84	267
rs:WP_015349066	methylenetetrahydrofolate dehydrogenase [Myxococcus stipitatus].	48.81	293	139	3	3	295	2	283	2e-84	267
rs:WP_010093190	5,10-methylene-tetrahydrofolate dehydrogenase [Ornithinibacillus scapharcae].	46.90	290	143	3	1	290	1	279	2e-84	267
rs:WP_008094863	5,10-methylene-tetrahydrofolate dehydrogenase [Haloferax prahovense].	48.96	288	145	2	5	292	4	289	2e-84	267
rs:WP_046997178	5,10-methylene-tetrahydrofolate cyclohydrolase [Arcobacter butzleri].	47.90	286	139	3	5	290	3	278	2e-84	267
rs:WP_033623471	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	2e-84	267
rs:WP_008383223	5,10-methylene-tetrahydrofolate dehydrogenase [Halogeometricum pallidum].	49.30	286	143	2	4	289	3	286	2e-84	267
rs:WP_044016465	methenyltetrahydrofolate cyclohydrolase [Treponema sp. OMZ 838].	47.57	288	146	2	3	290	2	284	2e-84	268
rs:WP_002787454	methenyltetrahydrofolate cyclohydrolase [Microcystis aeruginosa].	47.60	292	142	2	2	293	5	285	2e-84	267
rs:NP_001193024	probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Bos taurus].	49.66	298	143	3	3	294	51	347	2e-84	269
rs:WP_007341185	methenyltetrahydrofolate cyclohydrolase [Neisseria bacilliformis].	48.29	292	137	3	1	290	1	280	2e-84	267
rs:WP_021072757	5,10-methylene-tetrahydrofolate dehydrogenase [haloarchaeon 3A1_DGR].	49.13	287	144	2	4	290	3	287	2e-84	267
rs:WP_013859608	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus coagulans].	48.11	291	140	4	1	291	1	280	2e-84	267
rs:WP_000525712	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	2e-84	267
tr:J0JEJ3_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	2e-84	267
rs:WP_013280695	5,10-methylene-tetrahydrofolate dehydrogenase [Butyrivibrio proteoclasticus].	50.34	292	131	4	1	289	1	281	2e-84	267
rs:WP_026773531	5,10-methylene-tetrahydrofolate cyclohydrolase [Sediminibacterium sp. OR43].	47.54	284	149	0	5	288	3	286	2e-84	267
rs:WP_001133652	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	2e-84	267
rs:WP_013757787	5,10-methylene-tetrahydrofolate dehydrogenase [Treponema brennaborense].	46.92	292	152	2	1	292	1	289	2e-84	267
rs:WP_028588986	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus panacisoli].	48.29	292	140	3	1	292	1	281	2e-84	267
tr:A9QPI2_METI4	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.52	292	160	2	3	293	4	294	2e-84	267
rs:WP_026525700	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. MB2005].	50.17	289	135	3	1	289	1	280	2e-84	267
rs:WP_010345647	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus peoriae].	49.66	292	136	4	1	292	1	281	2e-84	267
rs:WP_034394197	methenyltetrahydrofolate cyclohydrolase [Delftia acidovorans].	50.17	295	131	6	1	292	1	282	2e-84	267
rs:WP_029691823	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus hyovaginalis].	49.65	288	135	2	6	293	5	282	2e-84	267
rs:WP_013029480	5,10-methylene-tetrahydrofolate dehydrogenase [Sideroxydans lithotrophicus].	48.63	292	139	4	1	292	1	281	2e-84	267
rs:WP_000525730	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	2e-84	267
tr:I9XKD6_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	2e-84	267
rs:WP_025709791	MULTISPECIES: bifunctional protein FolD [Bacillus].	49.32	292	137	4	1	292	1	281	2e-84	267
rs:WP_035627086	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium C6A11].	51.57	287	128	3	3	289	2	277	2e-84	267
rs:WP_002015067	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus].	49.66	292	136	4	1	292	1	281	2e-84	267
rs:WP_028460519	methenyltetrahydrofolate cyclohydrolase [Nitrosomonas cryotolerans].	48.97	292	138	3	1	292	1	281	2e-84	267
sp:FOLD_ARCB4	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.90	286	139	3	5	290	3	278	2e-84	267
sp:FOLD_BACC7	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.66	292	136	4	1	292	1	281	2e-84	267
rs:WP_041042424	5,10-methylene-tetrahydrofolate cyclohydrolase [Tolypothrix campylonemoides].	47.72	285	143	2	2	286	5	283	2e-84	267
rs:WP_015169274	5,10-methylene-tetrahydrofolate dehydrogenase [Synechococcus sp. PCC 7502].	50.35	284	135	2	3	286	2	279	2e-84	267
rs:WP_043036591	bifunctional protein FolD [Streptococcus equi].	48.28	290	140	2	4	293	3	282	2e-84	267
rs:WP_013393356	5,10-methylene-tetrahydrofolate dehydrogenase [Achromobacter xylosoxidans].	49.32	292	137	3	1	292	1	281	2e-84	267
rs:WP_023989247	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus].	49.66	292	136	4	1	292	1	281	2e-84	267
tr:D0E8K7_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.28	290	140	2	1	290	1	280	2e-84	267
rs:WP_009860813	5,10-methylene-tetrahydrofolate dehydrogenase [Roseburia inulinivorans].	50.00	284	131	4	3	286	2	274	2e-84	266
rs:WP_018886378	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus massiliensis].	48.29	292	140	3	1	292	1	281	2e-84	267
rs:WP_000525720	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	2e-84	267
sp:FOLD_BACC2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.32	292	137	4	1	292	1	281	2e-84	267
rs:WP_025715890	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. 1-18].	48.97	292	138	4	1	292	1	281	2e-84	267
rs:WP_043998379	5,10-methylene-tetrahydrofolate cyclohydrolase [Microcystis aeruginosa].	48.28	290	139	2	2	291	5	283	2e-84	267
rs:WP_013835082	methenyltetrahydrofolate cyclohydrolase [Thioalkalimicrobium cyclicum].	47.95	292	142	2	1	292	1	282	2e-84	267
rs:WP_033589404	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	2e-84	267
tr:T0DNS0_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	15	292	2e-84	267
rs:WP_007430923	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus sp. Aloe-11].	49.66	292	136	4	1	292	1	281	2e-84	267
tr:I9RWA1_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	2e-84	267
rs:WP_021303489	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	8	285	2e-84	267
rs:WP_034354542	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter sp. MIT 09-6949].	47.02	285	140	4	5	289	3	276	2e-84	267
rs:WP_033582949	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	2e-84	267
rs:XP_009466941	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Nipponia nippon].	50.34	298	141	3	3	294	62	358	2e-84	269
sp:FOLD_HAMD5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.37	289	145	2	1	289	1	279	2e-84	267
rs:WP_001133658	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	3e-84	267
rs:WP_007742741	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia].	51.55	291	130	3	1	291	1	280	3e-84	267
sp:FOLD_DELAS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	295	131	6	1	292	1	282	3e-84	267
rs:WP_001133645	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	3e-84	267
rs:WP_026634317	methenyltetrahydrofolate cyclohydrolase [Dyella japonica].	49.31	290	137	2	1	290	1	280	3e-84	267
rs:WP_026943305	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter rodentium].	47.04	287	141	3	4	290	2	277	3e-84	266
tr:J0PFB3_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	3e-84	267
rs:WP_013111680	5,10-methylene-tetrahydrofolate dehydrogenase [Planctomyces limnophilus].	48.62	290	142	1	1	290	1	283	3e-84	267
tr:J0J2F1_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.14	288	148	2	5	292	8	285	3e-84	267
rs:WP_029567980	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	3e-84	267
rs:WP_026670060	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. AE3006].	50.17	289	135	3	1	289	1	280	3e-84	267
rs:WP_039089434	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	3e-84	267
rs:WP_000525722	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	3e-84	267
gp:CP002571_579	Bifunctional 5,10-methylene tetrahydrofolate dehydrogenase/ 5,10 methylene tetrahydrofolate cyclohydrolase [Helicobacter pylori 2017]	45.14	288	148	2	5	292	8	285	3e-84	267
rs:WP_039270949	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus polymyxa].	49.66	292	136	4	1	292	1	281	3e-84	267
rs:WP_007474305	5,10-methylene-tetrahydrofolate dehydrogenase [Listeria fleischmannii].	50.17	289	133	4	3	291	2	279	3e-84	266
rs:WP_000525710	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	3e-84	267
rs:WP_021907737	bifunctional protein FolD [Eubacterium sp. CAG:146].	49.30	284	133	3	6	289	5	277	3e-84	266
rs:WP_033745673	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	3e-84	267
rs:WP_042875514	bifunctional protein FolD [Bacillus cereus].	49.66	292	136	4	1	292	1	281	3e-84	267
rs:WP_046956367	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus cereus].	50.00	292	135	4	1	292	1	281	3e-84	267
rs:WP_033452567	methenyltetrahydrofolate cyclohydrolase [Bordetella bronchiseptica].	48.29	292	140	3	1	292	1	281	3e-84	266
rs:WP_026515731	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. MC2021].	48.45	291	137	5	1	289	1	280	3e-84	267
rs:WP_025041276	methenyltetrahydrofolate cyclohydrolase [Nitrosospira briensis].	48.63	292	127	4	1	286	1	275	3e-84	266
rs:WP_013965967	5,10-methylene-tetrahydrofolate dehydrogenase [Nitrosomonas sp. Is79A3].	49.32	292	137	3	1	292	1	281	3e-84	267
rs:XP_003080249	Methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase (ISS) [Ostreococcus tauri].	46.94	294	150	2	1	292	1	290	3e-84	268
rs:WP_040758111	5,10-methylene-tetrahydrofolate cyclohydrolase [Sporosarcina newyorkensis].	46.76	293	145	4	1	293	1	282	3e-84	267
rs:WP_027995076	methenyltetrahydrofolate cyclohydrolase [Simplicispira psychrophila].	48.97	292	138	4	1	292	1	281	3e-84	267
rs:WP_000525705	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	3e-84	267
rs:WP_000226742	bifunctional protein FolD [Bacillus cereus].	49.32	292	137	4	1	292	1	281	3e-84	266
rs:WP_019938787	5,10-methylene-tetrahydrofolate dehydrogenase [Bordetella sp. FB-8].	49.66	292	136	3	1	292	1	281	3e-84	266
rs:XP_010001937	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Chaetura pelagica].	50.67	298	140	3	3	294	192	488	3e-84	273
rs:WP_029439886	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus thuringiensis].	49.66	292	136	4	1	292	1	281	3e-84	266
rs:WP_004268898	methenyltetrahydrofolate cyclohydrolase [Microcystis aeruginosa].	47.60	292	142	2	2	293	5	285	3e-84	266
tr:G1M6Y9_AILME	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAMEP00000015109}; Flags: Fragment;	49.33	298	144	3	3	294	14	310	3e-84	267
rs:WP_028548775	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. UNC451MF].	48.29	292	140	4	1	292	1	281	3e-84	266
rs:WP_027085054	5,10-methylene-tetrahydrofolate cyclohydrolase [Cohnella panacarvi].	50.00	292	135	3	1	292	1	281	3e-84	266
rs:WP_016344928	bifunctional protein FolD [Burkholderia sp. RPE64].	48.63	292	139	4	1	292	1	281	3e-84	266
rs:WP_006306747	methylenetetrahydrofolate dehydrogenase [Caldisalinibacter kiritimatiensis].	48.80	291	138	2	1	291	1	280	3e-84	266
rs:WP_025365157	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus polymyxa].	49.32	292	137	4	1	292	1	281	3e-84	266
rs:WP_016526234	hypothetical protein [Treponema maltophilum].	47.28	294	152	2	1	294	1	291	3e-84	267
sp:FOLD_BACCZ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.32	292	137	4	1	292	1	281	3e-84	266
rs:WP_013802221	5,10-methylene-tetrahydrofolate dehydrogenase [Delftia sp. Cs1-4].	50.17	295	131	6	1	292	1	282	3e-84	266
rs:WP_046993033	5,10-methylene-tetrahydrofolate cyclohydrolase [Arcobacter butzleri].	47.90	286	139	3	5	290	3	278	3e-84	266
rs:WP_042793255	methenyltetrahydrofolate cyclohydrolase [Achromobacter xylosoxidans].	49.32	292	137	3	1	292	1	281	3e-84	266
rs:WP_014535379	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	3e-84	266
rs:WP_045672679	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus beijingensis].	49.66	292	136	4	1	292	1	281	3e-84	266
rs:WP_038317699	methenyltetrahydrofolate cyclohydrolase [Kingella kingae].	48.97	290	138	2	1	290	1	280	3e-84	266
rs:WP_005021662	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pullorum].	46.34	287	143	3	4	290	2	277	3e-84	266
rs:WP_017313373	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Stigonematales].	46.67	285	146	2	2	286	5	283	3e-84	267
rs:WP_006526696	5,10-methylene-tetrahydrofolate dehydrogenase [Solobacterium moorei].	48.26	288	138	3	4	291	3	279	3e-84	266
rs:WP_043935926	MULTISPECIES: bifunctional protein FolD [Bacillus].	49.32	292	137	4	1	292	1	281	3e-84	266
rs:WP_003821025	5,10-methylene-tetrahydrofolate dehydrogenase [Bordetella bronchiseptica].	47.42	291	142	3	1	291	1	280	4e-84	266
rs:WP_042636413	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	4e-84	266
rs:WP_015039205	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bordetella].	48.29	292	140	3	1	292	9	289	4e-84	266
tr:W0JPX1_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.52	287	138	4	4	289	3	286	4e-84	267
rs:WP_022249686	bifunctional protein FolD [Eubacterium sp. CAG:274].	49.66	290	135	4	3	292	2	280	4e-84	266
rs:WP_021743966	tetrahydrofolate dehydrogenase [Leptotrichia sp. oral taxon 879].	48.41	283	134	3	5	286	3	274	4e-84	266
tr:I4HWX1_MICAE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.95	292	141	2	2	293	18	298	4e-84	267
rs:WP_005436241	5,10-methylene-tetrahydrofolate dehydrogenase [Sutterella wadsworthensis].	50.51	293	134	4	1	293	1	282	4e-84	266
tr:J0SA31_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.14	288	148	2	5	292	8	285	4e-84	266
rs:XP_011223187	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Ailuropoda melanoleuca].	49.33	298	144	3	3	294	34	330	4e-84	268
rs:WP_027319267	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroidetes bacterium SCGC AAA027-G08].	47.20	286	149	1	5	288	3	288	4e-84	266
tr:L8ISQ3_9CETA	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:ELR59605.1}; Flags: Fragment;	49.33	298	144	3	3	294	4	300	4e-84	267
rs:WP_013707211	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfobacca acetoxidans].	49.66	292	144	3	1	290	1	291	4e-84	267
rs:WP_000226741	bifunctional protein FolD [Bacillus cereus].	49.32	292	137	4	1	292	1	281	4e-84	266
rs:WP_000226717	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus].	49.32	292	137	4	1	292	1	281	4e-84	266
rs:WP_021682959	tetrahydrofolate dehydrogenase [Ruminococcus callidus].	48.26	288	139	3	3	290	2	279	4e-84	266
rs:WP_021638964	tetrahydrofolate dehydrogenase [Clostridium sp. KLE 1755].	48.26	288	138	4	3	290	2	278	4e-84	266
rs:WP_000525709	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	4e-84	266
rs:WP_014533682	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	4e-84	266
rs:WP_006620001	methenyltetrahydrofolate cyclohydrolase [Arthrospira platensis].	47.42	291	147	2	3	293	2	286	4e-84	266
rs:WP_010547116	5,10-methylene-tetrahydrofolate dehydrogenase [gamma proteobacterium HIMB30].	51.19	293	137	2	1	293	1	287	4e-84	266
rs:WP_004060361	5,10-methylene-tetrahydrofolate dehydrogenase [Haloferax mediterranei].	49.65	288	143	2	5	292	4	289	4e-84	267
rs:WP_042346037	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. G2(2012b)].	48.62	290	138	4	1	290	1	279	4e-84	266
rs:WP_010224606	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	48.28	290	140	2	1	290	1	280	4e-84	266
rs:XP_002501973	predicted protein [Micromonas sp. RCC299].	45.58	294	154	2	2	293	10	299	4e-84	267
rs:XP_010836478	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Bison bison bison].	49.66	298	143	3	3	294	51	347	4e-84	268
rs:WP_025447947	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	4e-84	266
rs:WP_035429521	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. UNC322MFChir4.1].	49.66	292	136	4	1	292	1	281	4e-84	266
rs:WP_019895735	methenyltetrahydrofolate cyclohydrolase [Thiomicrospira halophila].	45.67	289	147	2	1	289	1	279	4e-84	266
rs:WP_002486581	tetrahydrofolate dehydrogenase [Staphylococcus epidermidis].	47.24	290	142	3	1	290	1	279	4e-84	266
sp:FOLD_BACCR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.32	292	137	4	1	292	1	281	4e-84	266
rs:WP_045554144	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria innocua].	49.83	289	134	4	3	291	2	279	4e-84	266
rs:WP_018292420	5,10-methylene-tetrahydrofolate dehydrogenase [Gallionella sp. SCGC AAA018-N21].	49.66	292	136	3	1	292	1	281	4e-84	266
tr:I9WQS7_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.14	288	148	2	5	292	8	285	4e-84	266
rs:WP_001133650	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	4e-84	266
rs:WP_000226739	bifunctional protein FolD [Bacillus cereus].	49.66	292	136	4	1	292	1	281	4e-84	266
rs:WP_042475298	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. FF3].	49.83	293	136	4	1	293	1	282	4e-84	266
rs:WP_033750834	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	4e-84	266
rs:WP_000525701	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	4e-84	266
tr:F9DN58_9BACL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.76	293	145	4	1	293	7	288	4e-84	266
rs:WP_001133641	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	4e-84	266
rs:WP_014643710	5,10-methylene-tetrahydrofolate dehydrogenase [Halobacillus halophilus].	49.14	291	136	3	1	291	1	279	4e-84	266
sp:FOLD_METPP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.46	293	140	3	1	293	1	282	4e-84	266
tr:A0A090M335_OSTTA	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase,conserved site {ECO:0000313|EMBL:CEF98650.1};	46.94	294	150	2	1	292	87	376	4e-84	269
rs:WP_006676759	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus dendritiformis].	47.42	291	142	4	1	291	1	280	4e-84	266
tr:A0A0D9L3R8_9NEIS	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:KJJ09950.1};	49.13	289	137	2	1	289	32	310	4e-84	267
rs:WP_026823493	methenyltetrahydrofolate cyclohydrolase [Arsenophonus nasoniae].	47.42	291	143	3	1	291	1	281	4e-84	266
sp:FOLD_BACC1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.66	292	136	4	1	292	1	281	4e-84	266
rs:WP_015237980	methylenetetrahydrofolate dehydrogenase [Kinetoplastibacterium blastocrithidii].	46.08	293	147	3	1	293	1	282	4e-84	266
rs:WP_016116259	FolD protein [Bacillus cereus].	49.66	292	136	4	1	292	1	281	4e-84	266
rs:WP_046439758	5,10-methylene-tetrahydrofolate cyclohydrolase [Ruminococcus sp. N15.MGS-57].	50.35	288	132	4	3	290	2	278	4e-84	266
rs:XP_006212594	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Vicugna pacos].	51.03	290	135	3	11	294	1	289	4e-84	266
rs:XP_010055184	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X2 [Eucalyptus grandis].	48.97	292	143	2	3	292	71	358	4e-84	269
rs:WP_000226728	bifunctional protein FolD [Bacillus thuringiensis].	49.66	292	136	4	1	292	1	281	4e-84	266
rs:WP_042670305	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus equi].	48.28	290	140	2	4	293	3	282	4e-84	266
rs:XP_007430724	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2-like [Python bivittatus].	50.34	298	141	4	3	294	51	347	5e-84	268
sp:FOLD_ANAVT	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.07	285	142	2	2	286	5	283	5e-84	266
sp:FOLD_BACHD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.14	291	136	3	1	291	1	279	5e-84	266
tr:D2ZYL9_NEIMU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.13	289	137	2	1	289	32	310	5e-84	267
rs:WP_038532170	5,10-methylene-tetrahydrofolate cyclohydrolase [Thermocrinis ruber].	50.68	294	131	4	2	293	4	285	5e-84	266
rs:XP_010055182	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X1 [Eucalyptus grandis].	48.97	292	143	2	3	292	73	360	5e-84	269
sp:FOLD_STRE4	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.28	290	140	2	4	293	3	282	5e-84	266
tr:K2K0B3_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.14	288	148	2	5	292	8	285	5e-84	266
rs:WP_033475561	methenyltetrahydrofolate cyclohydrolase [Bordetella bronchiseptica].	47.42	291	142	3	1	291	1	280	5e-84	266
rs:WP_039086553	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	5e-84	266
sp:FOLD_STRS7	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.93	290	141	2	4	293	3	282	5e-84	266
rs:XP_003974934	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Takifugu rubripes].	52.00	300	136	4	3	295	30	328	5e-84	268
rs:WP_000525719	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	5e-84	266
rs:WP_029525107	methenyltetrahydrofolate cyclohydrolase [Polaromonas glacialis].	48.63	292	144	3	1	292	1	286	5e-84	266
rs:XP_009111472	PREDICTED: bifunctional protein FolD 4, chloroplastic [Brassica rapa].	48.96	288	141	2	6	291	62	345	5e-84	268
rs:XP_011563827	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Plutella xylostella].	48.31	296	144	4	3	291	2	295	5e-84	266
rs:WP_038313436	methenyltetrahydrofolate cyclohydrolase [Kingella kingae].	48.62	290	139	2	1	290	1	280	5e-84	266
rs:WP_038309427	methenyltetrahydrofolate cyclohydrolase [Kingella kingae].	48.62	290	139	2	1	290	1	280	5e-84	266
rs:WP_008824847	5,10-methylene-tetrahydrofolate dehydrogenase [Haloplasma contractile].	46.21	290	146	2	1	290	1	280	5e-84	266
rs:WP_033590706	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	5e-84	266
rs:WP_013889810	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter bizzozeronii].	46.71	289	138	4	5	291	3	277	5e-84	266
rs:WP_041169139	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	5e-84	266
rs:WP_016184588	FolD protein [Enterococcus sulfureus].	49.31	288	134	4	5	292	4	279	5e-84	266
rs:WP_038324210	5,10-methylene-tetrahydrofolate cyclohydrolase [bacterium MS4].	51.03	290	131	4	3	292	2	280	5e-84	266
rs:WP_007977754	5,10-methylene-tetrahydrofolate dehydrogenase [Haladaptatus paucihalophilus].	47.40	289	150	2	4	292	3	289	5e-84	266
rs:WP_007988721	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Glaciecola].	49.48	291	137	2	1	291	1	281	5e-84	266
rs:WP_022334536	bifunctional protein FolD [Clostridium sp. CAG:452].	50.00	288	133	4	3	290	2	278	5e-84	266
rs:XP_006339533	PREDICTED: bifunctional protein FolD 4, chloroplastic-like [Solanum tuberosum].	47.95	292	146	2	2	291	75	362	5e-84	269
rs:WP_028888963	5,10-methylene-tetrahydrofolate cyclohydrolase [Tenacibaculum ovolyticum].	47.22	288	152	0	5	292	3	290	5e-84	266
rs:WP_043980026	methenyltetrahydrofolate cyclohydrolase [Novosphingobium sp. P6W].	50.00	276	128	2	15	290	1	266	5e-84	266
rs:WP_005032695	5,10-methylene-tetrahydrofolate dehydrogenase [Holophaga foetida].	48.97	290	138	2	1	290	1	280	6e-84	266
rs:WP_020259350	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Aminicenans sakinawicola].	46.96	296	151	3	1	290	1	296	6e-84	266
rs:WP_029443281	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus thuringiensis].	49.32	292	137	4	1	292	1	281	6e-84	266
rs:WP_008514972	5,10-methylene-tetrahydrofolate dehydrogenase [Dethiobacter alkaliphilus].	47.08	291	143	2	1	291	1	280	6e-84	266
rs:XP_001782212	predicted protein [Physcomitrella patens].	48.29	292	145	2	3	292	14	301	6e-84	266
rs:WP_001133651	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	6e-84	266
tr:S9UVG5_9TRYP	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EPY32888.1}; SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:EPY33912.1};	46.08	293	147	3	1	293	13	294	6e-84	266
rs:WP_007345100	5,10-methylene-tetrahydrofolate dehydrogenase [Halorubrum terrestre].	50.52	287	138	4	4	289	3	286	6e-84	266
rs:XP_001233663	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Gallus gallus].	49.66	298	143	3	3	294	46	342	6e-84	268
rs:XP_010661739	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X2 [Vitis vinifera].	47.95	292	146	2	2	291	70	357	6e-84	268
rs:WP_018368308	tetrahydrofolate dehydrogenase [Streptococcus entericus].	49.14	291	138	2	3	293	2	282	6e-84	266
rs:WP_004052867	FolD protein [Eubacterium plexicaudatum].	48.10	289	139	3	3	291	2	279	6e-84	266
rs:WP_001133640	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	6e-84	266
rs:WP_045517533	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus niacini].	49.15	293	138	4	1	293	1	282	6e-84	266
rs:WP_004292452	5,10-methylene-tetrahydrofolate dehydrogenase [Thauera sp. 63].	48.29	292	144	3	1	292	1	285	6e-84	266
rs:WP_001976861	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	6e-84	266
rs:WP_038130028	methenyltetrahydrofolate cyclohydrolase [Verrucomicrobia bacterium SCGC AAA168-F10].	49.13	289	143	3	3	290	2	287	6e-84	266
sp:FOLD_BACWK	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.32	292	137	4	1	292	1	281	6e-84	266
rs:WP_010499087	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus elgii].	48.63	292	139	4	1	292	1	281	6e-84	266
tr:I2DG82_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	15	292	6e-84	266
rs:WP_036599418	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sophorae].	48.80	291	138	3	1	291	1	280	6e-84	266
rs:WP_016311710	methylenetetrahydrofolate dehydrogenase [Paenibacillus barengoltzii].	49.14	291	137	3	1	291	1	280	6e-84	266
rs:WP_035994936	methenyltetrahydrofolate cyclohydrolase [Burkholderia caribensis].	51.20	291	131	3	1	291	1	280	6e-84	266
sp:FOLD_PSEA6	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.14	291	138	2	1	291	1	281	6e-84	266
rs:WP_012405146	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia phymatum].	51.20	291	131	3	1	291	1	280	7e-84	266
rs:XP_011563826	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Plutella xylostella].	48.31	296	144	4	3	291	34	327	7e-84	268
rs:WP_038812507	methenyltetrahydrofolate cyclohydrolase [Staphylococcus epidermidis].	47.24	290	142	3	1	290	1	279	7e-84	266
rs:WP_010437123	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.59	290	142	2	1	290	1	280	7e-84	266
tr:A0A083YG99_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	8	285	7e-84	266
rs:WP_013647499	5,10-methylene-tetrahydrofolate dehydrogenase [Nitrosomonas sp. AL212].	47.99	298	132	4	1	292	1	281	7e-84	266
rs:XP_011204521	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Bactrocera dorsalis].	49.66	294	141	4	3	290	10	302	7e-84	267
rs:WP_003056938	tetrahydrofolate dehydrogenase [Streptococcus dysgalactiae].	47.93	290	141	2	4	293	3	282	7e-84	266
tr:K2KWN1_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	7e-84	266
rs:WP_007543548	5,10-methylene-tetrahydrofolate dehydrogenase [Listeria fleischmannii].	50.52	289	132	4	3	291	2	279	7e-84	266
rs:WP_001133647	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	7e-84	266
rs:WP_010284563	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus timonensis].	48.45	291	140	3	1	291	1	281	7e-84	266
rs:WP_002033943	MULTISPECIES: bifunctional protein FolD [Bacillus cereus group].	49.32	292	137	4	1	292	1	281	7e-84	266
rs:WP_025784721	5,10-methylene-tetrahydrofolate cyclohydrolase [Sporosarcina sp. D27].	48.97	290	137	4	1	290	1	279	7e-84	266
rs:WP_045491623	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. StFLB209].	51.39	288	133	2	2	289	14	294	7e-84	266
rs:WP_033583778	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	7e-84	266
rs:WP_029712014	hypothetical protein [BRC1 bacterium SCGC AAA257-C11].	47.24	290	146	2	1	290	1	283	7e-84	266
rs:WP_008275774	methenyltetrahydrofolate cyclohydrolase [Cyanothece sp. CCY0110].	46.42	293	151	2	2	294	5	291	7e-84	266
rs:WP_015435084	bifunctional protein FolD [Azoarcus sp. KH32C].	48.81	293	143	4	1	293	1	286	7e-84	266
rs:WP_022778478	5,10-methylene-tetrahydrofolate dehydrogenase [Butyrivibrio sp. AE3009].	48.80	291	136	5	1	289	1	280	7e-84	266
tr:A0A099T465_METMT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.40	289	141	3	4	292	8	285	7e-84	266
rs:WP_006949938	5,10-methylene-tetrahydrofolate dehydrogenase [Prevotella marshii].	46.94	294	155	1	1	294	1	293	7e-84	266
rs:WP_015017218	tetrahydrofolate dehydrogenase [Streptococcus dysgalactiae].	47.93	290	141	2	4	293	3	282	7e-84	266
rs:XP_011204522	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X3 [Bactrocera dorsalis].	49.66	294	141	4	3	290	9	301	7e-84	266
rs:WP_018766174	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus sp. 105MF].	49.32	292	137	4	1	292	1	281	8e-84	266
rs:WP_028538376	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. J14].	49.48	291	136	3	1	291	1	280	8e-84	266
rs:WP_001949548	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	8e-84	266
tr:I4FJ54_MICAE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.28	290	139	2	2	291	18	296	8e-84	266
tr:A0A0D6AL49_9CHRO	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:BAQ63532.1};	47.44	293	148	3	1	293	1	287	8e-84	266
rs:WP_033597883	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	8e-84	266
rs:WP_001952064	tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	8e-84	266
rs:WP_031214677	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	8e-84	266
rs:WP_018364071	tetrahydrofolate dehydrogenase [Streptococcus caballi].	47.46	295	145	2	3	297	2	286	8e-84	266
rs:WP_024647974	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.59	290	142	2	1	290	1	280	8e-84	265
rs:WP_022476618	bifunctional protein FolD [Clostridium sp. CAG:273].	49.65	288	134	4	3	290	2	278	8e-84	265
rs:WP_028818114	methenyltetrahydrofolate cyclohydrolase [beta proteobacterium SCGC AAA028-K02].	48.29	292	141	3	1	292	1	282	8e-84	265
rs:WP_025908880	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus flexus].	48.62	290	137	4	1	290	1	278	8e-84	265
rs:WP_000525714	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	8e-84	266
rs:XP_006188761	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Camelus ferus].	50.69	290	136	3	11	294	1	289	8e-84	266
tr:T5D043_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	15	292	8e-84	266
rs:WP_002502084	tetrahydrofolate dehydrogenase [Staphylococcus epidermidis].	47.24	290	142	3	1	290	1	279	8e-84	265
rs:WP_025259221	methenyltetrahydrofolate cyclohydrolase [Pseudomonas cichorii].	47.59	290	142	2	1	290	1	280	8e-84	265
tr:S7PWY0_MYOBR	RecName: Full=C-X-C motif chemokine {ECO:0000256|RuleBase:RU361149};	49.66	298	143	3	3	294	114	410	8e-84	270
rs:WP_018151670	hypothetical protein [Leeia oryzae].	46.02	289	146	2	1	289	1	279	9e-84	265
rs:WP_039675201	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Sulfurospirillum].	48.25	286	137	3	4	289	2	276	9e-84	265
rs:WP_000226734	MULTISPECIES: bifunctional protein FolD [Bacillus cereus group].	49.32	292	137	4	1	292	1	281	9e-84	265
rs:WP_036062182	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria fleischmannii].	50.52	289	132	4	3	291	2	279	9e-84	265
rs:WP_027359016	methenyltetrahydrofolate cyclohydrolase [Desulforegula conservatrix].	46.15	299	156	2	1	294	1	299	9e-84	266
rs:WP_046236526	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae pv. coryli].	47.59	290	142	2	1	290	1	280	9e-84	265
rs:WP_001133649	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	9e-84	266
rs:WP_016857666	methenyltetrahydrofolate cyclohydrolase [Candidatus Hamiltonella defensa].	46.02	289	146	2	1	289	1	279	9e-84	265
rs:WP_039091990	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	9e-84	266
rs:WP_039200965	5,10-methylene-tetrahydrofolate cyclohydrolase [Aphanizomenon flos-aquae].	47.72	285	143	2	2	286	4	282	9e-84	266
rs:WP_022554958	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus dysgalactiae].	47.93	290	141	2	4	293	3	282	9e-84	265
tr:H5SJA1_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.80	297	143	3	3	294	2	288	9e-84	265
rs:WP_015041817	methylenetetrahydrofolate dehydrogenase [Bordetella bronchiseptica].	47.42	291	142	3	1	291	1	280	9e-84	265
tr:A0A034TW93_9VIBR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	53.33	255	108	4	38	291	1	245	9e-84	264
rs:WP_001958628	tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	9e-84	266
rs:WP_043820508	methenyltetrahydrofolate cyclohydrolase [Delftia sp. RIT313].	50.17	295	131	6	1	292	1	282	9e-84	265
tr:T2SIZ5_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	9e-84	265
rs:WP_000226729	MULTISPECIES: bifunctional protein FolD [Bacillus cereus group].	49.32	292	137	4	1	292	1	281	9e-84	265
rs:WP_026589989	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. UNC437CL72CviS29].	49.66	292	136	4	1	292	1	281	9e-84	265
tr:A0A098EMC1_9BACL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.83	293	136	4	1	293	1	282	9e-84	265
rs:WP_021307088	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	9e-84	265
rs:XP_011990914	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Ovis aries musimon].	49.33	298	144	3	3	294	51	347	1e-83	267
rs:WP_041137601	5,10-methylene-tetrahydrofolate cyclohydrolase [Sulfurovum sp. AS07-7].	49.31	288	136	2	4	291	2	279	1e-83	265
rs:WP_003415751	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.59	290	142	2	1	290	1	280	1e-83	265
rs:WP_022337522	bifunctional protein FolD [Firmicutes bacterium CAG:94].	50.88	285	129	4	6	290	7	280	1e-83	265
rs:WP_019428963	5,10-methylene-tetrahydrofolate dehydrogenase [Limnohabitans sp. Rim47].	50.00	292	135	4	1	292	1	281	1e-83	265
tr:A0A0D3DZN5_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo9g002430.1};	48.61	288	142	2	6	291	62	345	1e-83	268
rs:XP_007628808	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Cricetulus griseus].	50.00	298	142	3	3	294	113	409	1e-83	269
rs:WP_033790147	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.10	288	151	2	5	292	8	285	1e-83	265
rs:WP_010530945	5,10-methylene-tetrahydrofolate dehydrogenase [Lentibacillus jeotgali].	47.59	290	141	3	1	290	1	279	1e-83	265
rs:WP_042962168	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	1e-83	265
rs:WP_019532748	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus ginsengihumi].	48.95	286	135	3	1	286	1	275	1e-83	265
rs:WP_026086058	5,10-methylene-tetrahydrofolate cyclohydrolase [Fischerella muscicola].	46.67	285	146	2	2	286	5	283	1e-83	265
rs:WP_031244418	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	1e-83	265
rs:WP_040934088	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochloron didemni].	48.43	287	141	3	1	286	1	281	1e-83	265
rs:WP_033621404	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	1e-83	265
rs:XP_007087037	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2-like [Panthera tigris altaica].	49.33	298	144	3	3	294	38	334	1e-83	267
tr:E3YPZ9_9LIST	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.48	289	135	4	3	291	2	279	1e-83	265
rs:WP_033595556	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	1e-83	265
rs:WP_001868905	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	8	285	1e-83	265
rs:WP_042383520	5,10-methylene-tetrahydrofolate cyclohydrolase [Geobacillus thermoglucosidasius].	49.48	291	136	4	1	291	1	280	1e-83	265
tr:T2T0W2_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	1e-83	265
rs:WP_022225390	bifunctional protein FolD [Clostridium sp. CAG:253].	51.56	289	129	4	3	291	2	279	1e-83	265
tr:T0DMK5_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	15	292	1e-83	266
rs:WP_046176947	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus dysgalactiae].	47.93	290	141	2	4	293	3	282	1e-83	265
rs:WP_000525685	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	1e-83	265
rs:WP_008309025	5,10-methylene-tetrahydrofolate dehydrogenase [Haloarcula amylolytica].	49.12	285	143	2	4	288	3	285	1e-83	266
rs:WP_001960475	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	1e-83	265
tr:I9Q2U9_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	8	285	1e-83	265
sp:FOLD_SYNE7	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.99	296	140	3	1	295	1	286	1e-83	265
tr:T0DU86_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	15	292	1e-83	265
rs:WP_008583530	5,10-methylene-tetrahydrofolate dehydrogenase [Halorubrum hochstenium].	50.52	287	138	4	4	289	3	286	1e-83	265
rs:WP_009674917	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus].	47.60	292	142	3	1	292	1	281	1e-83	265
rs:XP_002987769	hypothetical protein SELMODRAFT_126842, partial [Selaginella moellendorffii].	46.08	293	152	2	2	292	8	296	1e-83	266
rs:WP_046493167	methenyltetrahydrofolate cyclohydrolase [Candidatus Hamiltonella defensa].	46.02	289	146	2	1	289	1	279	1e-83	265
rs:WP_003466369	methylenetetrahydrofolate dehydrogenase [Gracilibacillus halophilus].	46.05	291	146	3	1	291	1	280	1e-83	265
sp:FOLD_ACIET	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.00	294	131	6	1	291	1	281	1e-83	265
tr:E8QLP1_HELP4	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	1e-83	265
rs:WP_003531868	5,10-methylene-tetrahydrofolate dehydrogenase [[Clostridium] leptum].	51.74	288	128	4	3	290	2	278	1e-83	265
rs:XP_002269224	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X1 [Vitis vinifera].	47.95	292	146	2	2	291	97	384	1e-83	268
rs:WP_000226724	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus group].	49.66	292	136	4	1	292	1	281	1e-83	265
rs:WP_033760006	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	1e-83	265
rs:WP_000525691	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	1e-83	265
tr:H0WLD7_OTOGA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOGAP00000002452}; Flags: Fragment;	48.66	298	146	3	3	294	4	300	1e-83	266
rs:XP_008691554	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Ursus maritimus].	49.33	298	144	3	3	294	42	338	1e-83	267
rs:WP_001926138	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	1e-83	265
rs:WP_035014485	methenyltetrahydrofolate cyclohydrolase [Catenovulum agarivorans].	49.30	286	135	2	1	286	1	276	1e-83	265
rs:WP_005886407	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium mortiferum].	46.53	288	142	4	6	292	4	280	1e-83	265
rs:XP_011972592	PREDICTED: LOW QUALITY PROTEIN: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like isoform X2 [Ovis aries musimon].	51.19	295	137	3	3	291	37	330	1e-83	267
rs:WP_028058152	hypothetical protein [Solirubrobacter sp. URHD0082].	47.26	292	143	3	1	292	1	281	1e-83	265
rs:XP_012068784	PREDICTED: bifunctional protein FolD 4, chloroplastic-like [Jatropha curcas].	48.12	293	146	2	1	291	71	359	1e-83	268
tr:F6I6I4_VITVI	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CCB62377.1};	47.95	292	146	2	2	291	93	380	1e-83	268
rs:WP_024495625	methenyltetrahydrofolate cyclohydrolase [Candidatus Schmidhempelia bombi].	48.45	291	139	3	1	291	1	280	1e-83	265
rs:WP_024694811	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.93	290	141	2	1	290	1	280	1e-83	265
rs:XP_006288063	hypothetical protein CARUB_v10001296mg [Capsella rubella].	47.08	291	148	2	3	291	60	346	1e-83	267
rs:WP_013519052	5,10-methylene-tetrahydrofolate dehydrogenase [Alicycliphilus denitrificans].	50.68	294	129	6	1	291	1	281	1e-83	265
rs:WP_035157796	5,10-methylene-tetrahydrofolate cyclohydrolase [Calothrix sp. 336/3].	48.29	292	143	4	2	292	5	289	1e-83	265
rs:WP_001930594	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	1e-83	265
rs:WP_004035679	hypothetical protein [Clostridium sp. ASF356].	49.66	292	136	4	1	292	1	281	1e-83	265
rs:WP_022340918	bifunctional protein FolD [Roseburia sp. CAG:309].	51.59	283	123	3	6	288	5	273	1e-83	265
rs:WP_033916432	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter sputorum].	49.31	290	136	3	4	293	2	280	1e-83	265
rs:WP_000525703	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	1e-83	265
rs:XP_002993744	hypothetical protein SELMODRAFT_236807 [Selaginella moellendorffii].	46.37	289	149	2	6	292	5	289	1e-83	265
rs:WP_024644950	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.93	290	141	2	1	290	1	280	1e-83	265
sp:FOLD2_BORPE	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.95	292	141	3	1	292	1	281	1e-83	265
rs:WP_007876219	5,10-methylene-tetrahydrofolate dehydrogenase [Herbaspirillum sp. CF444].	48.29	292	140	3	1	292	1	281	1e-83	265
rs:XP_009446011	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Pan troglodytes].	49.33	298	144	3	3	294	51	347	1e-83	267
rs:WP_039408437	methenyltetrahydrofolate cyclohydrolase [Morococcus cerebrosus].	48.79	289	138	2	1	289	1	279	1e-83	265
tr:F8CUK1_GEOTC	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.14	291	137	4	1	291	4	283	1e-83	265
rs:WP_018755133	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus terrigena].	48.29	292	140	3	1	292	1	281	1e-83	265
sp:FOLD_NOSS1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.07	285	142	2	2	286	5	283	1e-83	265
rs:XP_011801527	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Colobus angolensis palliatus].	50.52	287	135	3	3	283	37	322	1e-83	266
tr:H2QPP1_PANTR	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000027781}; Flags: Fragment;	49.33	298	144	3	3	294	41	337	1e-83	266
rs:WP_025699037	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus forsythiae].	49.48	291	136	3	1	291	1	280	1e-83	265
rs:WP_046159318	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus dysgalactiae].	47.93	290	141	2	4	293	3	282	1e-83	265
sp:FOLD4_ARATH	RecName: Full=Bifunctional protein FolD 4, chloroplastic; AltName: Full=Protein EMBRYO DEFECTIVE 3127; AltName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase 4; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Flags: Precursor;	48.11	291	145	2	3	291	69	355	1e-83	267
rs:XP_001990439	GH18238 [Drosophila grimshawi].	46.60	294	149	3	3	290	2	293	1e-83	265
rs:WP_004418524	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	47.24	290	143	2	1	290	1	280	1e-83	265
rs:WP_021320506	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus equi].	47.93	290	141	2	4	293	3	282	1e-83	265
rs:WP_008179967	methenyltetrahydrofolate cyclohydrolase [Moorea producens].	46.53	288	148	2	4	291	3	284	1e-83	265
rs:WP_001948259	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	1e-83	265
rs:WP_002849828	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter fetus].	50.69	288	131	4	4	291	2	278	1e-83	265
tr:A0A087H8Y6_ARAAL	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFK38588.1};	46.26	294	152	2	2	293	8	297	1e-83	265
rs:WP_001967799	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	1e-83	265
rs:WP_028399142	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus panaciterrae].	48.62	290	138	4	1	290	1	279	2e-83	265
tr:I9VVT5_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	2e-83	265
rs:WP_007866457	5,10-methylene-tetrahydrofolate dehydrogenase [Polaromonas sp. CF318].	49.66	292	136	4	1	292	1	281	2e-83	265
rs:WP_001869970	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	8	285	2e-83	265
gpu:CP011805_2401	Bifunctional protein FolD [Altererythrobacter marensis]	48.97	292	145	1	1	292	1	288	2e-83	265
tr:A0A0C2M0R2_9CYAN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.67	285	146	2	2	286	5	283	2e-83	265
rs:WP_000525682	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	2e-83	265
rs:WP_013146831	methenyltetrahydrofolate cyclohydrolase [Methylotenera versatilis].	46.18	288	145	2	1	288	1	278	2e-83	265
rs:WP_016172529	tetrahydrofolate dehydrogenase [Enterococcus dispar].	49.30	286	135	2	3	288	2	277	2e-83	265
rs:WP_046239222	methenyltetrahydrofolate cyclohydrolase [Delftia acidovorans].	49.83	295	132	6	1	292	1	282	2e-83	265
rs:WP_003321371	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus alcalophilus].	47.08	291	142	3	1	291	1	279	2e-83	265
rs:WP_001944528	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	2e-83	265
rs:WP_042178589	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. FSL R7-0331].	49.14	291	137	4	1	291	1	280	2e-83	265
tr:R7UT61_CAPTE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELU06551.1, ECO:0000313|EnsemblMetazoa:CapteP148292};	49.48	289	139	3	11	293	1	288	2e-83	265
rs:WP_014040444	5,10-methylene-tetrahydrofolate dehydrogenase [Haloarcula hispanica].	49.12	285	143	2	4	288	3	285	2e-83	265
rs:WP_016175686	FolD protein [Enterococcus saccharolyticus].	49.31	288	135	4	5	292	4	280	2e-83	265
rs:WP_016447109	MULTISPECIES: FolD protein [Delftia].	49.83	295	132	6	1	292	1	282	2e-83	265
rs:WP_002953468	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter showae].	50.00	286	132	3	5	290	3	277	2e-83	265
rs:WP_042633544	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	2e-83	265
rs:WP_026655048	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Butyrivibrio].	50.00	292	132	5	1	289	1	281	2e-83	265
rs:WP_000226731	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus].	48.97	292	138	4	1	292	1	281	2e-83	265
rs:WP_008090516	tetrahydrofolate dehydrogenase [Streptococcus ictaluri].	48.28	290	140	3	4	293	3	282	2e-83	265
rs:WP_003787562	methenyltetrahydrofolate cyclohydrolase [Kingella kingae].	48.62	290	139	2	1	290	1	280	2e-83	265
rs:WP_033599037	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	2e-83	265
tr:A0A059ZVM3_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.29	292	139	4	1	291	1	281	2e-83	265
rs:WP_001956520	tetrahydrofolate dehydrogenase [Helicobacter pylori].	45.14	288	148	2	5	292	10	287	2e-83	265
rs:WP_038243809	5,10-methylene-tetrahydrofolate cyclohydrolase [Virgibacillus sp. Vm-5].	47.59	290	141	3	1	290	1	279	2e-83	265
rs:WP_022564768	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Pantoea carbekii].	50.00	290	134	3	1	290	1	279	2e-83	265
rs:WP_044012591	methenyltetrahydrofolate cyclohydrolase [Legionella massiliensis].	45.17	290	149	2	1	290	1	280	2e-83	265
rs:WP_033593170	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	2e-83	265
rs:WP_019141661	5,10-methylene-tetrahydrofolate dehydrogenase [Herbaspirillum massiliense].	48.29	292	140	3	1	292	1	281	2e-83	265
rs:WP_043029483	bifunctional protein FolD [Streptococcus equi].	47.93	290	141	2	4	293	3	282	2e-83	265
rs:XP_006445097	hypothetical protein CICLE_v10020642mg [Citrus clementina].	48.63	292	144	2	2	291	83	370	2e-83	268
rs:WP_003755680	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Neisseria].	50.17	289	134	2	1	289	1	279	2e-83	265
sp:FOLD_CYAP8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.44	289	139	3	2	288	5	285	2e-83	265
gp:CP000266_464	5,10-methylene-tetrahydrofolate dehydrogenase [Shigella flexneri 5 str. 8401]	51.64	275	123	3	15	289	1	265	2e-83	264
rs:WP_034114223	methenyltetrahydrofolate cyclohydrolase [Comamonadaceae bacterium BICA1-1].	47.20	286	140	3	1	286	1	275	2e-83	265
rs:WP_009373882	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Anoxybacillus].	47.42	291	142	4	1	291	1	280	2e-83	265
tr:J0HG44_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	2e-83	265
rs:XP_006445096	hypothetical protein CICLE_v10020642mg [Citrus clementina].	48.63	292	144	2	2	291	79	366	2e-83	267
sp:FOLD_LISMC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.48	289	135	4	3	291	2	279	2e-83	265
rs:WP_022286741	bifunctional protein FolD [Ruminococcus sp. CAG:57].	50.00	288	133	4	3	290	2	278	2e-83	265
sp:FOLD_AKKM8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.28	290	146	3	4	292	2	288	2e-83	265
rs:WP_045054221	5,10-methylene-tetrahydrofolate cyclohydrolase [Chroococcales cyanobacterium CENA595].	48.06	283	141	2	4	286	7	283	2e-83	265
sp:FOLD_HAHCH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.65	288	135	2	3	290	12	289	2e-83	265
tr:G1N5H5_MELGA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMGAP00000007206};	49.83	297	142	3	3	293	31	326	2e-83	266
rs:WP_023886976	FolD protein [Eikenella corrodens].	48.10	289	140	2	1	289	1	279	2e-83	265
rs:WP_033455341	methenyltetrahydrofolate cyclohydrolase [Bordetella bronchiseptica].	47.42	291	142	3	1	291	1	280	2e-83	265
rs:XP_005874877	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Myotis brandtii].	49.66	290	139	3	11	294	1	289	2e-83	265
rs:WP_003249257	5,10-methylene-tetrahydrofolate dehydrogenase [Geobacillus thermoglucosidasius].	49.14	291	137	4	1	291	1	280	2e-83	265
rs:WP_024029800	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus vireti].	47.78	293	142	3	1	293	1	282	2e-83	265
rs:WP_021042562	5,10-methylene-tetrahydrofolate dehydrogenase [halophilic archaeon J07HX64].	48.79	289	144	2	4	292	3	287	2e-83	265
rs:WP_033533057	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria innocua].	49.48	289	135	4	3	291	2	279	2e-83	265
rs:WP_041599405	methenyltetrahydrofolate cyclohydrolase [Hahella chejuensis].	49.65	288	135	2	3	290	10	287	2e-83	265
rs:WP_001932824	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	2e-83	265
rs:WP_020061572	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus sp. 123MFChir2].	49.66	292	136	4	1	292	1	281	2e-83	265
rs:XP_011821537	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Mandrillus leucophaeus].	48.99	298	145	3	3	294	51	347	2e-83	266
rs:WP_036064955	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria grandensis].	50.52	289	132	4	3	291	2	279	2e-83	265
rs:NP_001241997	uncharacterized protein LOC100797215 [Glycine max].	47.60	292	147	2	2	291	50	337	2e-83	266
rs:WP_046513406	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. SA1-12].	47.42	291	142	4	1	291	1	280	2e-83	265
rs:WP_044195902	5,10-methylene-tetrahydrofolate cyclohydrolase [Oscillatoria acuminata].	48.42	285	141	2	2	286	5	283	2e-83	265
rs:WP_016080321	FolD protein [Bacillus cereus].	48.97	292	138	4	1	292	1	281	2e-83	265
rs:WP_000525689	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	2e-83	265
rs:WP_000525711	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	2e-83	265
tr:J0LPJ0_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	2e-83	265
rs:WP_031249294	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	2e-83	265
tr:T5DI95_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	15	292	2e-83	265
rs:WP_043025467	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus equi].	47.59	290	142	2	4	293	3	282	2e-83	264
rs:WP_022193945	bifunctional protein FolD [Clostridium sp. CAG:217].	50.69	288	131	4	3	290	2	278	2e-83	264
rs:XP_006377670	hypothetical protein POPTR_0011s10100g [Populus trichocarpa].	46.42	293	151	2	3	293	9	297	2e-83	265
rs:WP_015057875	methylenetetrahydrofolate dehydrogenase [Streptococcus dysgalactiae].	47.59	290	142	2	4	293	3	282	2e-83	264
rs:WP_047212991	methenyltetrahydrofolate cyclohydrolase [Pandoraea thiooxydans].	47.95	292	141	4	1	292	1	281	2e-83	264
rs:WP_019217139	hypothetical protein [Legionella tunisiensis].	47.77	291	142	2	1	291	1	281	2e-83	264
rs:WP_014622515	FolD bifunctional protein [Streptococcus equi].	47.59	290	142	2	4	293	3	282	2e-83	264
rs:WP_020151710	hypothetical protein [Verrucomicrobia bacterium SCGC AAA164-M04].	49.13	289	143	3	3	290	2	287	2e-83	265
rs:WP_003304374	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.24	290	143	2	1	290	1	280	2e-83	264
rs:WP_042201584	5,10-methylene-tetrahydrofolate cyclohydrolase [Nodularia spumigena].	47.37	285	144	2	2	286	5	283	2e-83	265
rs:WP_004889600	5,10-methylene-tetrahydrofolate dehydrogenase [Anoxybacillus flavithermus].	48.29	292	140	4	1	292	1	281	2e-83	264
rs:WP_042629781	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	2e-83	265
rs:WP_017344331	5,10-methylene-tetrahydrofolate dehydrogenase [Halorubrum sp. T3].	50.17	287	139	4	4	289	3	286	2e-83	265
gp:CP002293_1128	Methylenetetrahydrofolate dehydrogenase (NADP(+)) [Geobacillus sp. Y4.1MC1]	49.14	291	137	4	1	291	4	283	2e-83	265
gpu:CP011125_3728	Methylenetetrahydrofolate dehydrogenase [Sandaracinus amylolyticus]	47.77	291	142	2	1	291	1	281	2e-83	264
rs:WP_007190309	5,10-methylene-tetrahydrofolate dehydrogenase [Haloarcula californiae].	48.77	285	144	2	4	288	3	285	2e-83	265
rs:XP_002073310	GK14062 [Drosophila willistoni].	46.28	296	152	4	3	292	2	296	2e-83	265
rs:WP_033185978	methenyltetrahydrofolate cyclohydrolase [Pseudoalteromonas sp. PLSV].	48.80	291	139	2	1	291	1	281	2e-83	264
rs:WP_035938212	methenyltetrahydrofolate cyclohydrolase [Burkholderia glathei].	48.97	292	138	4	1	292	1	281	2e-83	264
rs:WP_005013706	5,10-methylene-tetrahydrofolate dehydrogenase [Bordetella holmesii].	48.12	293	141	3	1	293	1	282	2e-83	264
rs:WP_020262783	5,10-methylene-tetrahydrofolate dehydrogenase [Aminicenantes bacterium SCGC AAA252-O11].	46.62	296	152	3	1	290	1	296	2e-83	265
rs:WP_039725763	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Oscillatoriophycideae].	47.02	285	145	2	4	288	3	281	2e-83	265
rs:WP_042228626	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus chitinolyticus].	47.60	292	142	3	1	292	1	281	2e-83	265
rs:WP_013897382	5,10-methylene-tetrahydrofolate dehydrogenase [Methanosalsum zhilinae].	47.42	291	141	4	3	293	7	285	2e-83	264
rs:WP_042458230	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. FF4].	48.12	293	141	4	1	293	1	282	3e-83	264
tr:A0A078L1M1_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.17	290	149	2	1	290	21	300	3e-83	265
tr:W0DGT7_9AQUI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.52	291	130	4	5	293	2	280	3e-83	264
rs:WP_026689320	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus aurantiacus].	48.46	293	140	4	1	293	1	282	3e-83	264
rs:WP_006461058	methenyltetrahydrofolate cyclohydrolase [Thioalkalimicrobium aerophilum].	47.26	292	144	2	1	292	1	282	3e-83	264
rs:WP_022450029	bifunctional protein FolD [Roseburia sp. CAG:303].	48.97	290	137	4	3	292	2	280	3e-83	264
rs:WP_022014585	bifunctional protein FolD [Clostridium sp. CAG:122].	52.11	284	125	4	3	286	2	274	3e-83	264
rs:WP_028367180	methenyltetrahydrofolate cyclohydrolase [Burkholderia sp. UYPR1.413].	51.20	291	131	3	1	291	1	280	3e-83	265
rs:WP_014931411	bifunctional protein FolD [Listeria monocytogenes].	49.13	289	136	4	3	291	2	279	3e-83	264
rs:WP_041269316	5,10-methylene-tetrahydrofolate cyclohydrolase [Geobacillus sp. Y4.1MC1].	49.14	291	137	4	1	291	1	280	3e-83	264
rs:WP_000226725	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus].	48.97	292	138	4	1	292	1	281	3e-83	264
rs:WP_039875215	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. FSL R7-0273].	48.11	291	140	3	1	291	1	280	3e-83	264
rs:WP_035047676	5,10-methylene-tetrahydrofolate cyclohydrolase [Anoxybacillus sp. KU2-6(11)].	47.60	292	142	4	1	292	1	281	3e-83	264
tr:K9TPB7_9CYAN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.42	285	141	2	2	286	4	282	3e-83	264
rs:WP_032134001	methenyltetrahydrofolate cyclohydrolase [Kingella kingae].	48.62	290	139	2	1	290	1	280	3e-83	264
rs:WP_046476673	methenyltetrahydrofolate cyclohydrolase [Filomicrobium sp. W].	47.10	293	145	2	1	293	1	283	3e-83	265
rs:XP_010981178	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Camelus dromedarius].	51.05	286	133	3	15	294	5	289	3e-83	264
tr:D1KC11_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.10	289	136	3	5	293	2	276	3e-83	264
rs:WP_014403006	methenyltetrahydrofolate cyclohydrolase [Frateuria aurantia].	48.29	292	141	2	1	292	1	282	3e-83	264
rs:XP_006758070	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Myotis davidii].	49.66	290	139	3	11	294	1	289	3e-83	264
rs:WP_032096874	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Alteromonas].	47.77	291	142	2	1	291	1	281	3e-83	264
rs:WP_025020268	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus equi].	47.39	287	137	3	5	291	4	276	3e-83	264
rs:WP_009550201	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderiales bacterium JOSHI_001].	47.46	295	144	4	1	295	1	284	3e-83	264
rs:WP_004093948	5,10-methylene-tetrahydrofolate dehydrogenase [Acetonema longum].	46.21	290	145	2	1	290	1	279	3e-83	264
rs:WP_023511037	5,10-methylene-tetrahydrofolate dehydrogenase [Sporolactobacillus laevolacticus].	48.29	292	140	3	1	292	1	281	3e-83	264
rs:WP_018165581	tetrahydrofolate dehydrogenase [Streptococcus henryi].	48.44	289	139	2	5	293	4	282	3e-83	264
rs:WP_026652797	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio proteoclasticus].	49.48	291	134	4	1	289	1	280	3e-83	264
rs:WP_033468400	methenyltetrahydrofolate cyclohydrolase [Bordetella bronchiseptica].	47.42	291	142	3	1	291	1	280	3e-83	264
rs:WP_000525698	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	3e-83	264
rs:WP_013943278	5,10-methylene-tetrahydrofolate dehydrogenase [Simkania negevensis].	46.69	287	142	3	5	290	3	279	3e-83	264
rs:WP_015320795	5,10-methylene-tetrahydrofolate dehydrogenase [Natronococcus occultus].	47.06	289	151	2	4	292	3	289	3e-83	265
rs:XP_011895831	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Cercocebus atys].	48.99	298	145	3	3	294	12	308	3e-83	265
rs:WP_043634333	methenyltetrahydrofolate cyclohydrolase [Chromobacterium haemolyticum].	51.40	286	129	3	1	286	1	276	3e-83	264
rs:WP_033621892	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	3e-83	264
rs:WP_002948575	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter showae].	50.00	286	132	3	5	290	3	277	3e-83	264
rs:XP_011782556	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Colobus angolensis palliatus].	48.99	298	145	3	3	294	51	347	3e-83	266
rs:WP_033777273	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	3e-83	264
tr:I9QSA2_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	3e-83	264
rs:WP_004592624	5,10-methylene-tetrahydrofolate dehydrogenase [Haloarcula japonica].	48.77	285	144	2	4	288	3	285	3e-83	264
rs:XP_005359537	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Microtus ochrogaster].	48.66	298	146	3	3	294	42	338	3e-83	266
tr:J0D4L2_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	8	285	3e-83	264
rs:WP_019404938	hypothetical protein [Chelatococcus sp. GW1].	48.44	289	144	2	2	289	6	290	3e-83	265
rs:XP_011204520	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Bactrocera dorsalis].	49.66	294	141	4	3	290	40	332	3e-83	266
rs:WP_014190968	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia sp. YI23].	49.32	292	137	4	1	292	1	281	3e-83	264
rs:WP_033764182	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.10	288	151	2	5	292	8	285	3e-83	264
rs:WP_009312491	methenyltetrahydrofolate cyclohydrolase [Neisseria sp. GT4A_CT1].	50.17	289	134	2	1	289	1	279	3e-83	264
sp:FOLD2_BORPA	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.95	292	141	3	1	292	1	281	3e-83	264
rs:WP_005982230	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium ulcerans].	47.06	289	141	4	5	292	2	279	3e-83	264
rs:WP_013657166	5,10-methylene-tetrahydrofolate dehydrogenase [Cellulosilyticum lentocellum].	49.31	290	136	4	3	292	2	280	3e-83	264
rs:WP_027420210	5,10-methylene-tetrahydrofolate cyclohydrolase [Crocinitomix catalasitica].	48.95	286	146	0	5	290	3	288	3e-83	264
rs:WP_024687894	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.93	290	141	2	1	290	1	280	3e-83	264
rs:WP_008350485	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia].	49.32	292	137	4	1	292	1	281	3e-83	264
rs:WP_013022986	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter mustelae].	46.85	286	140	4	5	290	3	276	3e-83	264
tr:G0AIF7_COLFT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.11	291	140	3	1	291	10	289	3e-83	264
rs:WP_027448553	5,10-methylene-tetrahydrofolate cyclohydrolase [Pontibacillus marinus].	47.08	291	143	3	1	291	1	280	3e-83	264
rs:WP_021922715	bifunctional protein FolD [Roseburia inulinivorans CAG:15].	49.65	284	132	4	3	286	2	274	4e-83	264
rs:WP_006875313	5,10-methylene-tetrahydrofolate dehydrogenase [Anaerotruncus colihominis].	51.55	291	130	4	1	291	1	280	4e-83	264
rs:WP_021291160	hypothetical protein [Virgibacillus sp. CM-4].	47.59	290	141	3	1	290	1	279	4e-83	264
rs:WP_021095251	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Anoxybacillus].	47.42	291	142	4	1	291	1	280	4e-83	264
rs:WP_033748398	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	4e-83	264
rs:WP_033743546	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	4e-83	264
tr:I0EHA8_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	4e-83	264
rs:WP_004594815	5,10-methylene-tetrahydrofolate dehydrogenase [Haloarcula japonica].	48.42	285	145	2	5	289	4	286	4e-83	264
rs:WP_002627251	methylenetetrahydrofolate dehydrogenase [Cystobacter fuscus].	47.92	288	139	3	3	290	2	278	4e-83	264
rs:XP_011189640	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X3 [Bactrocera cucurbitae].	49.66	294	141	4	3	290	9	301	4e-83	265
rs:WP_027112428	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium NK4A144].	50.35	288	134	3	3	290	2	280	4e-83	264
sp:FOLD_ANOFW	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.29	292	140	4	1	292	1	281	4e-83	264
rs:XP_009895343	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Picoides pubescens].	50.00	298	142	3	3	294	159	455	4e-83	269
rs:WP_012346671	5,10-methylene-tetrahydrofolate dehydrogenase [Leptothrix cholodnii].	50.17	289	128	6	1	286	1	276	4e-83	264
rs:WP_003791096	methenyltetrahydrofolate cyclohydrolase [Kingella kingae].	48.62	290	139	2	1	290	1	280	4e-83	264
sp:FOLD_LISMH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.13	289	136	4	3	291	2	279	4e-83	264
rs:WP_001954927	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	4e-83	264
sp:FOLD_PELPD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.83	291	135	3	3	293	2	281	4e-83	264
rs:WP_045830845	methenyltetrahydrofolate cyclohydrolase [Luteibacter yeojuensis].	49.48	289	136	2	1	289	1	279	4e-83	264
rs:WP_031580893	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium AC2028].	50.35	284	130	3	3	286	2	274	4e-83	263
rs:WP_012942878	5,10-methylene-tetrahydrofolate dehydrogenase [Haloterrigena turkmenica].	47.55	286	148	2	4	289	3	286	4e-83	264
rs:WP_028775634	5,10-methylene-tetrahydrofolate cyclohydrolase [Shimazuella kribbensis].	49.14	291	136	4	1	291	1	279	4e-83	264
tr:T2SR39_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	8	285	4e-83	264
rs:XP_005891322	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Bos mutus].	49.33	298	144	3	3	294	99	395	4e-83	267
rs:XP_011358834	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Pteropus vampyrus].	48.66	298	146	3	3	294	49	345	4e-83	266
tr:D3A885_NEISU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.88	283	125	3	9	289	14	284	4e-83	264
rs:WP_000525692	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	4e-83	264
rs:WP_041741319	methenyltetrahydrofolate cyclohydrolase [Collimonas fungivorans].	48.11	291	140	3	1	291	1	280	4e-83	263
tr:J0E150_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	8	285	4e-83	264
rs:XP_006094437	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Myotis lucifugus].	49.66	290	139	3	11	294	1	289	4e-83	264
rs:XP_005178674	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X3 [Musca domestica].	48.81	295	144	3	3	291	2	295	4e-83	264
tr:G4MG91_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.29	292	140	4	1	292	1	281	4e-83	264
rs:WP_016503541	bifunctional protein FolD [Candidatus Photodesmus katoptron].	46.90	290	143	3	1	289	1	280	4e-83	263
rs:WP_000525706	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	4e-83	264
gpu:CP009530_1383	Methylenetetrahydrofolate dehydrogenase (NADP+) [Methanosarcina barkeri 227]	47.26	292	143	2	2	293	7	287	4e-83	264
rs:WP_003822335	methenyltetrahydrofolate cyclohydrolase [Eikenella corrodens].	48.10	289	140	2	1	289	1	279	4e-83	264
rs:XP_011189639	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Bactrocera cucurbitae].	49.66	294	141	4	3	290	10	302	4e-83	265
rs:WP_002446145	tetrahydrofolate dehydrogenase [Staphylococcus epidermidis].	46.90	290	143	3	1	290	1	279	4e-83	264
rs:WP_034587448	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter magdeburgensis].	49.12	285	134	4	5	289	3	276	4e-83	263
rs:WP_033617032	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	4e-83	264
rs:WP_010930974	5,10-methylene-tetrahydrofolate dehydrogenase [Bordetella pertussis].	47.95	292	141	3	1	292	9	289	4e-83	264
rs:WP_020719737	hypothetical protein [Acidobacteriaceae bacterium KBS 96].	44.66	309	150	3	1	293	1	304	4e-83	264
rs:WP_042631780	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.10	288	151	2	5	292	8	285	4e-83	264
rs:WP_044204093	5,10-methylene-tetrahydrofolate cyclohydrolase [Coleofasciculus chthonoplastes].	45.67	289	151	2	4	292	7	289	4e-83	264
rs:WP_026959505	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Aliagarivorans].	48.97	290	138	3	1	290	1	280	4e-83	263
rs:WP_041201525	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	5e-83	264
rs:XP_004703256	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Echinops telfairi].	47.93	290	144	3	11	294	1	289	5e-83	264
rs:WP_038409546	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria monocytogenes].	49.48	289	135	4	3	291	2	279	5e-83	263
tr:V7HY71_9LACO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.55	286	136	3	6	291	1	272	5e-83	263
rs:WP_003051816	tetrahydrofolate dehydrogenase [Streptococcus dysgalactiae].	47.59	290	142	2	4	293	3	282	5e-83	263
rs:WP_002457465	tetrahydrofolate dehydrogenase [Staphylococcus epidermidis].	46.90	290	143	3	1	290	1	279	5e-83	263
rs:WP_006993122	methylenetetrahydrofolate dehydrogenase [Paraglaciecola mesophila].	48.80	291	139	2	1	291	1	281	5e-83	263
rs:WP_006983460	5,10-methylene-tetrahydrofolate dehydrogenase [Chthoniobacter flavus].	49.48	289	142	4	5	291	3	289	5e-83	264
rs:WP_038671710	5,10-methylene-tetrahydrofolate cyclohydrolase [Ruminococcus bicirculans].	50.00	288	133	4	3	290	2	278	5e-83	263
rs:WP_004318898	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter rectus].	50.00	286	132	3	5	290	3	277	5e-83	263
tr:A9PIC3_POPTR	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:ABK96126.1};	46.42	293	151	2	3	293	9	297	5e-83	264
rs:WP_033117169	5,10-methylene-tetrahydrofolate cyclohydrolase [Intestinimonas butyriciproducens].	49.31	290	133	4	1	290	1	276	5e-83	263
tr:V8NS58_OPHHA	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:ETE64801.1}; Flags: Fragment;	48.32	298	147	3	3	294	39	335	5e-83	265
rs:WP_027272761	methenyltetrahydrofolate cyclohydrolase [Leminorella grimontii].	46.21	290	146	3	1	290	1	280	5e-83	263
rs:WP_018923827	hypothetical protein [Salsuginibacillus kocurii].	47.89	284	136	3	4	286	3	275	5e-83	263
rs:WP_034474083	methenyltetrahydrofolate cyclohydrolase [Burkholderia zhejiangensis].	49.32	292	137	4	1	292	1	281	5e-83	263
sp:FOLD_LISMF	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.48	289	135	4	3	291	2	279	5e-83	263
rs:WP_044169906	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	5e-83	264
rs:WP_008524124	5,10-methylene-tetrahydrofolate dehydrogenase [Halorhabdus tiamatea].	47.37	285	148	2	4	288	3	285	5e-83	264
rs:XP_006729876	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2-like [Leptonychotes weddellii].	49.66	298	143	3	3	294	50	346	5e-83	266
tr:A0A022RP02_ERYGU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYU42212.1};	46.26	294	152	2	2	293	3	292	5e-83	264
rs:WP_038454646	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter iguaniorum].	49.48	287	134	3	4	290	2	277	5e-83	263
rs:WP_020288781	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. CFII64].	47.24	290	143	2	1	290	1	280	5e-83	263
rs:WP_000525680	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	5e-83	264
rs:XP_006840503	PREDICTED: bifunctional protein FolD 2 [Amborella trichopoda].	46.42	293	151	2	3	293	9	297	5e-83	264
rs:WP_016567611	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	47.24	290	143	2	1	290	1	280	5e-83	263
rs:WP_033623613	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	5e-83	264
rs:WP_000525700	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	5e-83	264
rs:WP_021305737	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	8	285	5e-83	263
tr:J0LHM0_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	8	285	5e-83	263
tr:J0MBW2_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	5e-83	263
rs:WP_025451278	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.10	288	151	2	5	292	8	285	5e-83	263
rs:WP_007327401	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodopirellula baltica].	47.51	301	140	3	1	290	1	294	5e-83	264
rs:WP_005794082	5,10-methylene-tetrahydrofolate dehydrogenase [Acidovorax delafieldii].	47.95	292	141	4	1	292	1	281	5e-83	263
rs:WP_022396699	bifunctional protein FolD [Akkermansia sp. CAG:344].	48.28	290	146	3	4	292	2	288	5e-83	263
rs:WP_009460304	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Fischerella].	45.96	285	148	2	2	286	5	283	5e-83	264
rs:WP_000525699	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	5e-83	263
rs:WP_000525683	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	5e-83	263
tr:J0S3I4_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	5e-83	263
rs:WP_034956165	methenyltetrahydrofolate cyclohydrolase [Erythrobacter sp. JL475].	48.63	292	146	1	1	292	1	288	5e-83	264
rs:WP_042264839	methenyltetrahydrofolate cyclohydrolase [Burkholderia heleia].	48.63	292	139	3	1	292	1	281	6e-83	263
sp:MTD2L_MOUSE	RecName: Full=Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2; AltName: Full=NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein; Short=MTHFD2-like; Includes: RecName: Full=NAD-dependent methylenetetrahydrofolate dehydrogenase; EC=1.5.1.15; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9;	49.33	298	144	3	3	294	42	338	6e-83	265
rs:WP_007828211	5,10-methylene-tetrahydrofolate dehydrogenase [Variovorax sp. CF313].	49.32	292	137	3	1	292	1	281	6e-83	263
rs:WP_000525739	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	6e-83	263
rs:WP_024674128	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.93	290	141	2	1	290	1	280	6e-83	263
tr:I9RXQ1_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	6e-83	263
rs:WP_001871076	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	8	285	6e-83	263
rs:XP_005178673	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Musca domestica].	48.81	295	144	3	3	291	8	301	6e-83	264
rs:WP_042577213	methenyltetrahydrofolate cyclohydrolase [Variovorax paradoxus].	48.97	292	138	3	1	292	1	281	6e-83	263
rs:WP_000525688	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	6e-83	263
tr:M7SLK1_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.75	288	152	2	5	292	8	285	6e-83	263
tr:F4D619_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	15	292	6e-83	264
rs:XP_011280120	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Felis catus].	49.33	298	144	3	3	294	91	387	6e-83	267
tr:J0JVT2_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	6e-83	263
rs:XP_008454369	PREDICTED: bifunctional protein FolD 2 isoform X1 [Cucumis melo].	47.44	293	148	2	3	293	9	297	6e-83	264
rs:WP_019500445	hypothetical protein [Pseudanabaena sp. PCC 6802].	47.72	285	143	2	2	286	3	281	6e-83	263
rs:WP_021581700	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	6e-83	263
rs:WP_023172381	5,10-methylene-tetrahydrofolate dehydrogenase [Gloeobacter kilaueensis].	46.94	294	149	3	1	293	1	288	6e-83	263
rs:WP_022290556	bifunctional protein FolD [Oscillibacter sp. CAG:155].	49.30	286	131	3	6	291	5	276	6e-83	263
rs:WP_022198797	MULTISPECIES: bifunctional protein FolD [Akkermansia].	47.93	290	147	3	4	292	2	288	6e-83	263
rs:XP_011895828	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Cercocebus atys].	48.99	298	145	3	3	294	51	347	6e-83	265
rs:WP_002145800	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus cereus].	48.97	292	138	4	1	292	1	281	6e-83	263
sp:FOLD_DESAA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.31	296	147	2	1	290	1	296	6e-83	264
tr:M7S480_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	6e-83	263
tr:A0A0B5GRD3_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.77	285	144	2	4	288	3	285	6e-83	264
rs:WP_001975471	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	6e-83	263
rs:WP_001961116	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	6e-83	263
tr:F3R4Q3_ENTFL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.26	288	139	3	5	292	4	281	6e-83	263
rs:WP_001942088	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	7e-83	263
rs:WP_032949839	bifunctional protein FolD [Lactococcus lactis].	48.79	289	137	3	5	293	3	280	7e-83	263
rs:XP_004465387	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Dasypus novemcinctus].	47.99	298	148	3	3	294	51	347	7e-83	265
rs:WP_033613157	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	7e-83	263
rs:WP_033600934	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	43.75	288	152	2	5	292	10	287	7e-83	263
rs:WP_033792629	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	7e-83	263
sp:FOLD_CAMFF	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.52	287	131	4	4	290	2	277	7e-83	263
rs:WP_006429943	5,10-methylene-tetrahydrofolate dehydrogenase [Natrinema versiforme].	47.55	286	148	2	4	289	3	286	7e-83	263
rs:WP_013144770	bifunctional protein FolD [Geobacillus sp. C56-T3].	48.80	291	138	4	1	291	1	280	7e-83	263
rs:WP_014775931	5,10-methylene-tetrahydrofolate dehydrogenase [Alistipes finegoldii].	50.35	282	131	3	5	286	2	274	7e-83	263
rs:WP_021850795	bifunctional protein FolD [Firmicutes bacterium CAG:791].	49.66	290	135	4	1	290	1	279	7e-83	263
rs:WP_009493797	methylenetetrahydrofolate dehydrogenase [Campylobacter showae].	49.65	286	133	3	5	290	3	277	7e-83	263
rs:WP_042201904	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. G4].	48.80	291	138	4	1	291	1	280	7e-83	263
rs:WP_031674630	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria monocytogenes].	49.13	289	136	4	3	291	2	279	7e-83	263
rs:WP_020936429	5,10-methylene-tetrahydrofolate dehydrogenase [Halorhabdus tiamatea].	47.37	285	148	2	4	288	10	292	7e-83	264
tr:B4VH15_9CYAN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.67	289	151	2	4	292	27	309	7e-83	264
gp:BX640433_279	bifunctional protein [includes: methylenetetrahydrofolate dehydrogenase and methylenetetrahydrofolate cyclohydrolase] [Bordetella parapertussis]	47.95	292	141	3	1	292	9	289	7e-83	263
rs:WP_019122828	hypothetical protein [Brevibacillus massiliensis].	48.47	295	141	4	1	295	1	284	7e-83	263
rs:WP_027107073	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus ceti].	48.10	289	139	3	5	293	4	281	7e-83	263
rs:WP_038486319	methenyltetrahydrofolate cyclohydrolase [Collimonas arenae].	48.11	291	140	3	1	291	1	280	7e-83	263
gpu:CP010423_1198	methenyltetrahydrofolate cyclohydrolase [Pragia fontium]	46.55	290	145	3	1	290	1	280	7e-83	263
rs:WP_028408722	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus].	47.59	290	140	4	1	290	1	278	7e-83	263
rs:WP_003135394	tetrahydrofolate dehydrogenase [Lactococcus garvieae].	48.62	290	138	4	4	293	2	280	7e-83	263
rs:WP_029714058	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus].	47.59	290	140	4	1	290	1	278	7e-83	263
sp:FOLD_LISMO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.13	289	136	4	3	291	2	279	7e-83	263
rs:XP_007953672	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Orycteropus afer afer].	48.62	290	142	3	11	294	1	289	8e-83	263
rs:WP_043964089	5,10-methylene-tetrahydrofolate cyclohydrolase [Anoxybacillus thermarum].	47.42	291	142	4	1	291	1	280	8e-83	263
rs:XP_011014434	PREDICTED: bifunctional protein FolD 2 [Populus euphratica].	46.42	293	151	2	3	293	9	297	8e-83	263
rs:WP_006186663	5,10-methylene-tetrahydrofolate dehydrogenase [Natrinema pallidum].	47.90	286	147	2	4	289	3	286	8e-83	263
rs:WP_006075896	5,10-methylene-tetrahydrofolate dehydrogenase [Halococcus saccharolyticus].	48.79	289	145	2	4	292	3	288	8e-83	263
rs:WP_027370479	methenyltetrahydrofolate cyclohydrolase [Desulfovermiculus halophilus].	46.46	297	152	2	1	290	1	297	8e-83	263
rs:WP_003766494	methenyltetrahydrofolate cyclohydrolase [Neisseria sicca].	49.83	289	135	2	1	289	1	279	8e-83	263
rs:WP_019576849	5,10-methylene-tetrahydrofolate dehydrogenase [Curvibacter lanceolatus].	49.65	286	133	4	1	286	1	275	8e-83	263
rs:WP_010821558	bifunctional protein FolD [Enterococcus faecalis].	48.96	288	136	4	5	292	4	280	8e-83	263
rs:WP_033461127	methenyltetrahydrofolate cyclohydrolase [Bordetella bronchiseptica].	47.95	292	141	3	1	292	1	281	8e-83	263
rs:WP_015783739	methenyltetrahydrofolate cyclohydrolase [Cyanothece sp. PCC 8802].	48.10	289	140	3	2	288	5	285	8e-83	263
rs:WP_001955840	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	8e-83	263
rs:WP_007105336	methylenetetrahydrofolate dehydrogenase [Paraglaciecola polaris].	49.83	291	136	2	1	291	1	281	8e-83	263
tr:T2SVB9_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	8e-83	263
tr:D2HBA7_AILME	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EFB28499.1}; Flags: Fragment;	49.66	290	139	3	11	294	1	289	8e-83	263
rs:WP_033761447	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	8e-83	263
rs:WP_017259363	5,10-methylene-tetrahydrofolate dehydrogenase [Pedobacter arcticus].	47.08	291	154	0	4	294	2	292	8e-83	263
rs:WP_040041956	methenyltetrahydrofolate cyclohydrolase [Herbaspirillum sp. TSA66].	48.97	292	138	3	1	292	1	281	8e-83	263
rs:XP_006288073	hypothetical protein CARUB_v10001306mg [Capsella rubella].	46.92	292	149	2	2	291	56	343	9e-83	265
sp:FOLD_GEOKA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.45	291	139	4	1	291	1	280	9e-83	263
rs:WP_022123297	bifunctional protein FolD [Clostridium sp. CAG:510].	49.65	288	134	3	3	290	2	278	9e-83	263
rs:WP_014624646	5,10-methylene-tetrahydrofolate dehydrogenase [Spirochaeta thermophila].	48.28	290	149	1	1	290	1	289	9e-83	263
rs:WP_028089054	5,10-methylene-tetrahydrofolate cyclohydrolase [Dolichospermum circinale].	47.37	285	144	2	2	286	5	283	9e-83	263
rs:WP_016451699	FolD protein [Delftia acidovorans].	49.49	295	133	6	1	292	1	282	9e-83	263
rs:XP_004383368	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Trichechus manatus latirostris].	48.66	298	146	3	3	294	46	342	9e-83	265
rs:WP_047004293	methenyltetrahydrofolate cyclohydrolase [Erythrobacter sp. KA37].	50.00	288	137	3	3	290	2	282	9e-83	263
sp:FOLD_METBF	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.42	291	142	2	2	292	7	286	9e-83	263
sp:FOLD_OCEIH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.92	288	139	3	3	290	2	278	9e-83	263
rs:WP_041941839	methenyltetrahydrofolate cyclohydrolase [Waddlia chondrophila].	47.16	282	139	3	6	286	3	275	9e-83	263
tr:D4M629_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.44	289	138	4	3	291	2	279	9e-83	263
rs:WP_016875702	methenyltetrahydrofolate cyclohydrolase [Chlorogloeopsis fritschii].	46.32	285	147	2	2	286	5	283	9e-83	263
tr:J0SUU7_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	9e-83	263
rs:WP_033101929	5,10-methylene-tetrahydrofolate cyclohydrolase [Thermoactinomyces daqus].	48.80	291	138	3	1	291	1	280	9e-83	263
sp:FOLD_LACLM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.79	289	137	3	5	293	3	280	9e-83	263
rs:WP_005897307	methenyltetrahydrofolate cyclohydrolase [Pseudomonas coronafaciens].	47.24	290	143	2	1	290	1	280	9e-83	263
rs:WP_000525708	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	9e-83	263
sp:FOLD_METAC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.60	294	143	3	3	293	8	290	9e-83	263
rs:WP_001133638	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	8	285	9e-83	263
rs:WP_026512793	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. LB2008].	49.32	292	134	5	1	289	1	281	9e-83	263
rs:WP_041075068	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. OxB-1].	46.42	293	146	4	1	293	1	282	1e-82	263
rs:WP_016306072	FolD protein [Lachnospiraceae bacterium A2].	49.30	284	133	4	3	286	2	274	1e-82	263
rs:WP_043030592	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus equi].	47.59	290	142	2	4	293	3	282	1e-82	263
rs:WP_033610849	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	1e-82	263
rs:WP_016617624	tetrahydrofolate dehydrogenase [Enterococcus faecalis].	48.61	288	137	4	5	292	4	280	1e-82	263
rs:WP_001924156	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	1e-82	263
rs:WP_006112395	5,10-methylene-tetrahydrofolate dehydrogenase [Halorubrum coriense].	50.00	286	141	2	4	289	3	286	1e-82	263
tr:L9L748_TUPCH	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:ELW70474.1}; Flags: Fragment;	48.32	298	147	3	3	294	4	300	1e-82	263
rs:WP_024668886	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.24	290	143	2	1	290	1	280	1e-82	263
rs:WP_007331358	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodopirellula baltica].	47.51	301	140	3	1	290	1	294	1e-82	263
rs:WP_025344217	5,10-methylene-tetrahydrofolate cyclohydrolase [Sulfurospirillum multivorans].	46.90	290	143	3	4	293	2	280	1e-82	263
rs:WP_028599853	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus pasadenensis].	47.77	291	141	4	1	291	1	280	1e-82	263
rs:WP_041959819	5,10-methylene-tetrahydrofolate cyclohydrolase [Sulfurospirillum arsenophilum].	46.90	290	143	3	4	293	2	280	1e-82	262
tr:A0A098E693_9ZZZZ	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:CEG11417.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CEG11417.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CEG11417.1};	44.76	286	147	2	5	290	4	278	1e-82	263
rs:WP_040286584	5,10-methylene-tetrahydrofolate cyclohydrolase [Sporosarcina koreensis].	48.96	288	136	4	5	292	4	280	1e-82	263
rs:WP_001945497	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	1e-82	263
rs:XP_006125479	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Pelodiscus sinensis].	50.00	298	142	3	3	294	133	429	1e-82	267
rs:WP_005360716	5,10-methylene-tetrahydrofolate dehydrogenase [Eubacterium ventriosum].	50.70	284	129	4	3	286	2	274	1e-82	262
rs:WP_027477098	methenyltetrahydrofolate cyclohydrolase [Curvibacter gracilis].	49.65	286	133	4	1	286	1	275	1e-82	263
tr:G3RH37_GORGO	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000014952}; Flags: Fragment;	48.99	298	145	3	3	294	4	300	1e-82	263
sp:FOLD_ACISJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.66	294	132	6	1	291	1	281	1e-82	263
tr:J0U2U5_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	8	285	1e-82	263
rs:WP_037957929	5,10-methylene-tetrahydrofolate cyclohydrolase [Sulfurospirillum sp. SCADC].	47.24	290	142	3	4	293	2	280	1e-82	262
rs:WP_009628036	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudanabaena biceps].	49.13	289	141	2	3	291	2	284	1e-82	263
rs:WP_001970811	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	1e-82	263
rs:WP_014601977	bifunctional protein FolD [Listeria monocytogenes].	49.13	289	136	4	3	291	2	279	1e-82	263
rs:WP_029047709	methenyltetrahydrofolate cyclohydrolase [Cupriavidus sp. amp6].	46.58	292	145	3	1	292	1	281	1e-82	263
rs:WP_022499159	bifunctional protein FolD [Firmicutes bacterium CAG:95].	50.35	284	130	4	3	286	2	274	1e-82	262
rs:XP_003790185	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Otolemur garnettii].	48.66	298	146	3	3	294	69	365	1e-82	265
rs:WP_023385469	5,10-methylene-tetrahydrofolate dehydrogenase [Campylobacter fetus].	50.17	287	132	4	4	290	2	277	1e-82	263
tr:I9V7A6_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	149	2	5	292	8	285	1e-82	263
tr:T2F4F3_LACLC	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.13	289	136	4	5	293	13	290	1e-82	263
sp:FOLD_ACTSZ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.05	291	147	2	1	291	1	281	1e-82	263
rs:WP_018717247	hypothetical protein [Arhodomonas aquaeolei].	49.48	289	136	3	1	289	1	279	1e-82	263
tr:J0E3S9_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	8	285	1e-82	263
tr:J0TRX2_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	8	285	1e-82	263
rs:WP_013056807	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus].	47.59	290	140	4	1	290	1	278	1e-82	263
rs:WP_019416953	5,10-methylene-tetrahydrofolate dehydrogenase [Anoxybacillus kamchatkensis].	47.08	291	143	4	1	291	1	280	1e-82	262
rs:WP_006318018	5,10-methylene-tetrahydrofolate dehydrogenase [Anoxybacillus flavithermus].	47.95	292	141	4	1	292	1	281	1e-82	262
rs:WP_000525696	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	1e-82	263
tr:Y1QGM0_LACLC	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.13	289	136	4	5	293	13	290	1e-82	263
tr:J0A6R9_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	8	285	1e-82	263
rs:WP_009341564	methenyltetrahydrofolate cyclohydrolase [Raphidiopsis brookii].	48.42	285	141	2	2	286	5	283	1e-82	263
rs:WP_033745628	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	1e-82	263
rs:WP_035034190	methenyltetrahydrofolate cyclohydrolase [Aquabacterium sp. NJ1].	50.00	294	131	6	1	291	1	281	1e-82	263
rs:WP_000525707	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	1e-82	263
tr:I4DRE1_PAPPL	SubName: Full=NAD-dependent methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:BAM20481.1};	49.16	299	137	4	3	291	8	301	1e-82	263
rs:WP_046713275	methenyltetrahydrofolate cyclohydrolase [Myxococcus fulvus].	48.12	293	142	3	3	295	2	284	1e-82	263
rs:XP_004229918	PREDICTED: bifunctional protein FolD 4, chloroplastic [Solanum lycopersicum].	47.59	290	146	2	4	291	78	363	1e-82	265
rs:WP_042625495	methenyltetrahydrofolate cyclohydrolase [Burkholderia glumae].	49.30	286	134	4	1	286	1	275	1e-82	263
rs:WP_000525695	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	1e-82	263
rs:WP_021059330	5,10-methylene-tetrahydrofolate dehydrogenase [Haloquadratum sp. J07HQX50].	48.96	288	143	2	5	292	4	287	1e-82	263
rs:WP_002760599	methenyltetrahydrofolate cyclohydrolase [Microcystis aeruginosa].	47.26	292	143	2	2	293	5	285	1e-82	262
rs:WP_043040287	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus equi].	47.59	290	142	2	4	293	3	282	1e-82	262
rs:WP_000525690	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	1e-82	263
rs:WP_010783958	bifunctional protein FolD [Enterococcus faecalis].	48.61	288	137	4	5	292	4	280	1e-82	262
rs:XP_004617956	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Sorex araneus].	47.65	298	149	3	3	294	19	315	1e-82	263
rs:XP_011358833	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Pteropus vampyrus].	48.66	298	146	3	3	294	78	374	1e-82	265
rs:WP_018499217	5,10-methylene-tetrahydrofolate dehydrogenase [Leptotrichia wadei].	47.59	290	140	3	5	293	3	281	1e-82	262
rs:WP_040260832	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. CB1].	49.83	295	137	3	1	295	1	284	1e-82	262
rs:WP_033775772	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	1e-82	263
rs:WP_010775679	bifunctional protein FolD [Enterococcus faecalis].	48.61	288	137	4	5	292	4	280	1e-82	262
rs:WP_000525713	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	1e-82	263
rs:WP_001133639	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	8	285	1e-82	263
rs:WP_003782479	methenyltetrahydrofolate cyclohydrolase [Kingella denitrificans].	50.00	290	135	2	1	290	1	280	1e-82	262
rs:WP_004339541	5,10-methylene-tetrahydrofolate dehydrogenase [Thauera linaloolentis].	47.95	292	145	4	1	292	1	285	1e-82	263
tr:A0A022QWX8_ERYGU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYU32089.1};	47.78	293	147	2	2	292	77	365	1e-82	265
rs:XP_007463276	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Lipotes vexillifer].	48.99	298	145	3	3	294	51	347	1e-82	265
tr:I9UZJ5_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	1e-82	263
rs:XP_011189638	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Bactrocera cucurbitae].	49.66	294	141	4	3	290	40	332	1e-82	265
rs:WP_028983830	5,10-methylene-tetrahydrofolate cyclohydrolase [Sporolactobacillus terrae].	47.96	294	140	5	1	293	1	282	1e-82	262
rs:WP_013214149	5,10-methylene-tetrahydrofolate dehydrogenase [Hyphomicrobium denitrificans].	50.17	293	134	3	1	292	1	282	1e-82	263
rs:WP_028210081	methenyltetrahydrofolate cyclohydrolase [Burkholderia mimosarum].	48.29	292	140	3	1	292	1	281	1e-82	262
rs:WP_044106511	5,10-methylene-tetrahydrofolate cyclohydrolase [cyanobacterium endosymbiont of Epithemia turgida].	47.44	293	144	3	5	295	8	292	1e-82	263
rs:WP_025026193	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus mannanilyticus].	46.76	293	145	3	1	293	1	282	1e-82	262
rs:WP_002495771	tetrahydrofolate dehydrogenase [Staphylococcus epidermidis].	46.90	290	143	3	1	290	1	279	1e-82	262
rs:WP_018287482	methenyltetrahydrofolate cyclohydrolase [zeta proteobacterium SCGC AB-137-I08].	47.40	289	142	3	2	290	6	284	1e-82	263
rs:WP_041168346	bifunctional protein FolD [Lactococcus lactis].	48.79	289	137	3	5	293	3	280	1e-82	262
rs:WP_028085286	5,10-methylene-tetrahydrofolate cyclohydrolase [Dolichospermum circinale].	47.37	285	144	2	2	286	5	283	1e-82	263
rs:XP_012435936	PREDICTED: bifunctional protein FolD 2 isoform X1 [Gossypium raimondii].	46.42	293	151	2	3	293	9	297	1e-82	263
rs:WP_036078606	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria cornellensis].	50.17	289	133	4	3	291	2	279	1e-82	262
rs:XP_004038880	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Gorilla gorilla gorilla].	48.99	298	145	3	3	294	18	314	1e-82	263
rs:WP_034355854	methenyltetrahydrofolate cyclohydrolase [Comamonas testosteroni].	50.17	295	131	5	1	292	1	282	1e-82	262
rs:WP_001929507	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	1e-82	263
rs:WP_046845752	methenyltetrahydrofolate cyclohydrolase [Hyphomicrobium sp. GJ21].	49.66	292	137	2	1	292	1	282	1e-82	263
rs:WP_001964429	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	1e-82	263
rs:WP_000525681	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	1e-82	263
rs:WP_014769077	5,10-methylene-tetrahydrofolate dehydrogenase [Sulfurospirillum barnesii].	47.20	286	140	3	4	289	2	276	1e-82	262
rs:WP_008295041	5,10-methylene-tetrahydrofolate dehydrogenase [Congregibacter litoralis].	49.32	294	142	4	1	292	1	289	2e-82	263
rs:XP_011990915	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Ovis aries musimon].	49.50	299	143	4	3	294	17	314	2e-82	263
rs:WP_000525715	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	2e-82	262
rs:WP_005672658	5,10-methylene-tetrahydrofolate dehydrogenase [Lautropia mirabilis].	46.26	294	146	4	1	293	1	283	2e-82	262
rs:WP_038594926	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. FSL H7-0357].	47.77	291	141	3	1	291	1	280	2e-82	262
rs:WP_004340837	5,10-methylene-tetrahydrofolate dehydrogenase [Comamonas testosteroni].	50.17	295	131	5	1	292	1	282	2e-82	262
tr:A0A091JJU5_9AVES	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFP20857.1}; Flags: Fragment;	49.66	294	132	3	3	294	4	283	2e-82	262
rs:XP_007519865	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Erinaceus europaeus].	49.33	298	144	3	3	294	42	338	2e-82	264
rs:WP_018399101	hypothetical protein [filamentous cyanobacterium ESFC-1].	46.44	295	152	2	1	295	1	289	2e-82	262
sp:FOLD_SYNAS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.63	292	148	2	1	292	1	290	2e-82	262
rs:WP_001942822	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	2e-82	262
rs:WP_045362114	methenyltetrahydrofolate cyclohydrolase [bacterium endosymbiont of Mortierella elongata FMR23-6].	49.66	292	136	4	1	292	1	281	2e-82	262
rs:WP_015375373	bifunctional protein FolD [Geobacillus sp. GHH01].	48.45	291	139	4	1	291	1	280	2e-82	262
rs:WP_045221160	methenyltetrahydrofolate cyclohydrolase [Desulfonatronum thioautotrophicum].	48.24	284	140	2	5	288	2	278	2e-82	262
tr:W5PZS5_SHEEP	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOARP00000015961};	49.31	290	140	3	11	294	1	289	2e-82	262
tr:J0A0C0_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	2e-82	262
rs:WP_004961165	5,10-methylene-tetrahydrofolate dehydrogenase [Haloarcula sinaiiensis].	48.42	285	145	2	4	288	3	285	2e-82	263
sp:FOLD1_HALMA	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.42	285	145	2	4	288	3	285	2e-82	263
rs:WP_006304887	5,10-methylene-tetrahydrofolate dehydrogenase [Centipeda periodontii].	49.31	290	134	4	3	290	2	280	2e-82	262
tr:F8LD27_9CHLA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.16	282	139	3	6	286	8	280	2e-82	262
sp:FOLD_BURM1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.14	291	137	3	1	291	1	280	2e-82	262
sp:FOLD_ENTFA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.61	288	137	4	5	292	4	280	2e-82	262
rs:XP_009061994	hypothetical protein LOTGIDRAFT_107221, partial [Lottia gigantea].	48.15	297	147	3	3	293	3	298	2e-82	263
rs:WP_016300706	FolD protein [Lachnospiraceae bacterium COE1].	48.76	283	134	4	4	286	3	274	2e-82	262
rs:XP_006143044	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Tupaia chinensis].	48.32	298	147	3	3	294	24	320	2e-82	263
rs:WP_013542142	5,10-methylene-tetrahydrofolate dehydrogenase [Variovorax paradoxus].	48.63	292	139	3	1	292	1	281	2e-82	262
rs:WP_019559638	5,10-methylene-tetrahydrofolate dehydrogenase [Caldimonas manganoxidans].	50.00	292	135	3	1	292	1	281	2e-82	262
rs:WP_019427965	5,10-methylene-tetrahydrofolate dehydrogenase [Limnohabitans sp. Rim28].	48.63	292	139	4	1	292	1	281	2e-82	262
rs:WP_005004529	methenyltetrahydrofolate cyclohydrolase [Nitrococcus mobilis].	48.11	291	141	2	1	291	1	281	2e-82	262
tr:A0A0B8RFK3_LISMN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.14	291	137	4	1	291	30	309	2e-82	263
rs:WP_021897947	bifunctional protein FolD [Faecalibacterium sp. CAG:1138].	50.17	291	133	4	3	293	2	280	2e-82	262
rs:WP_007084620	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus bataviensis].	48.46	293	140	4	1	293	1	282	2e-82	262
rs:WP_005534241	5,10-methylene-tetrahydrofolate dehydrogenase [Haloarcula argentinensis].	48.42	285	145	2	4	288	3	285	2e-82	263
rs:WP_024815048	methenyltetrahydrofolate cyclohydrolase [Acidovorax sp. JHL-3].	47.30	296	141	5	1	292	1	285	2e-82	262
rs:WP_006496801	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia cenocepacia].	48.45	291	139	3	1	291	1	280	2e-82	262
rs:WP_010822632	FolD protein [Enterococcus faecalis].	48.61	288	137	4	5	292	4	280	2e-82	262
rs:WP_008111775	5,10-methylene-tetrahydrofolate dehydrogenase [Herbaspirillum sp. YR522].	48.97	292	138	3	1	292	1	281	2e-82	262
rs:WP_039051043	methenyltetrahydrofolate cyclohydrolase [Comamonas testosteroni].	50.17	295	131	5	1	292	1	282	2e-82	262
sp:FOLD1_PSEU2	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.90	290	144	2	1	290	1	280	2e-82	262
rs:WP_019389594	methenyltetrahydrofolate cyclohydrolase [Kingella kingae].	48.28	290	140	2	1	290	1	280	2e-82	262
rs:XP_003265792	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Nomascus leucogenys].	48.99	298	145	3	3	294	51	347	2e-82	264
rs:WP_025917256	methenyltetrahydrofolate cyclohydrolase [Herminiimonas sp. CN].	50.00	292	135	4	1	292	1	281	2e-82	262
rs:WP_017323614	methenyltetrahydrofolate cyclohydrolase [cyanobacterium PCC 7702].	45.96	285	148	2	2	286	5	283	2e-82	262
rs:WP_013082935	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus megaterium].	47.24	290	141	4	1	290	1	278	2e-82	262
rs:XP_006535239	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Mus musculus].	49.33	298	144	3	3	294	70	366	2e-82	265
tr:A0A075HTG3_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.08	293	156	2	1	293	1	291	2e-82	262
rs:WP_040048792	methenyltetrahydrofolate cyclohydrolase [Burkholderia sp. MR1].	47.95	292	141	3	1	292	1	281	2e-82	262
tr:T0V202_LACLC	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.13	289	136	4	5	293	13	290	2e-82	262
rs:WP_027456609	methenyltetrahydrofolate cyclohydrolase [Dechloromonas agitata].	47.77	291	141	3	1	291	1	280	2e-82	262
sp:FOLD1_PSESM	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.24	290	143	2	1	290	1	280	2e-82	262
rs:XP_011732044	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Macaca nemestrina].	48.32	298	147	3	3	294	11	307	2e-82	263
rs:WP_002417215	tetrahydrofolate dehydrogenase [Enterococcus faecalis].	48.61	288	137	4	5	292	4	280	2e-82	262
rs:XP_005555122	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Macaca fascicularis].	48.32	298	147	3	3	294	12	308	2e-82	263
sp:FOLD_CYAA5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.55	290	149	2	2	291	5	288	2e-82	262
rs:WP_013698750	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia].	50.00	286	132	4	1	286	1	275	2e-82	262
rs:WP_016982407	methenyltetrahydrofolate cyclohydrolase [Pseudomonas amygdali].	47.24	290	143	2	1	290	1	280	2e-82	262
rs:WP_003368557	bifunctional protein FolD [Pseudomonas syringae].	47.24	290	143	2	1	290	1	280	2e-82	262
rs:XP_009643028	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Egretta garzetta].	49.66	294	132	3	3	294	3	282	2e-82	262
rs:WP_001968353	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	2e-82	262
rs:WP_019653147	5,10-methylene-tetrahydrofolate dehydrogenase [Variovorax paradoxus].	49.32	292	137	3	1	292	1	281	2e-82	262
rs:WP_025292702	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sanxanigenens].	48.80	291	138	2	2	292	4	283	2e-82	262
rs:WP_001947639	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.79	288	149	2	5	292	10	287	2e-82	262
rs:WP_040985339	5,10-methylene-tetrahydrofolate cyclohydrolase [Oceanobacillus sp. S5].	46.90	290	143	3	1	290	1	279	2e-82	262
rs:WP_009094239	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodopirellula sp. SWK7].	47.51	301	140	3	1	290	1	294	2e-82	262
rs:WP_010825091	FolD protein [Enterococcus faecalis].	48.61	288	137	4	5	292	4	280	2e-82	262
rs:WP_009425872	tetrahydrofolate dehydrogenase [Neisseria sp. oral taxon 020].	48.63	292	136	3	1	290	1	280	2e-82	262
rs:WP_017464811	tetrahydrofolate dehydrogenase [Staphylococcus epidermidis].	46.90	290	143	3	1	290	1	279	2e-82	262
rs:WP_000525716	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	2e-82	262
rs:WP_020229669	5,10-methylene-tetrahydrofolate dehydrogenase [Acidovorax sp. MR-S7].	50.00	294	131	6	1	291	1	281	2e-82	262
rs:WP_001939703	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	2e-82	262
rs:WP_046580888	methenyltetrahydrofolate cyclohydrolase [Burkholderia gladioli].	50.00	286	132	4	1	286	1	275	2e-82	262
sp:FOLD_HELPJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	8	285	2e-82	262
rs:WP_004517384	5,10-methylene-tetrahydrofolate dehydrogenase [Haloarcula vallismortis].	48.78	287	143	4	5	290	4	287	2e-82	262
rs:WP_002956369	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter cinaedi].	48.77	285	135	4	5	289	3	276	2e-82	262
rs:WP_019100233	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Chromobacterium].	51.40	286	129	3	1	286	1	276	2e-82	262
rs:WP_002403785	bifunctional protein FolD [Enterococcus faecalis].	48.26	288	138	4	5	292	4	280	2e-82	261
sp:FOLD_CYAP4	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.92	288	144	2	4	291	7	288	2e-82	262
rs:WP_022155122	bifunctional protein FolD [Firmicutes bacterium CAG:65].	50.35	284	130	3	3	286	2	274	2e-82	262
rs:WP_006648877	5,10-methylene-tetrahydrofolate dehydrogenase [Haloterrigena thermotolerans].	47.20	286	149	2	4	289	3	286	2e-82	262
tr:G8P5M2_LACLC	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.13	289	136	4	5	293	13	290	2e-82	262
rs:WP_027188646	methenyltetrahydrofolate cyclohydrolase [Desulfovibrio cuneatus].	46.88	288	146	1	5	292	3	283	2e-82	262
rs:WP_025752113	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus flexus].	47.24	290	141	4	1	290	1	278	2e-82	262
rs:WP_033025835	5,10-methylene-tetrahydrofolate cyclohydrolase [Geobacillus sp. CAMR5420].	48.45	291	139	4	1	291	1	280	2e-82	262
tr:J0L377_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	2e-82	262
rs:WP_002636343	5,10-methylene-tetrahydrofolate dehydrogenase [Myxococcus sp. (contaminant ex DSM 436)].	47.16	282	145	3	6	286	5	283	2e-82	262
rs:WP_044396751	methenyltetrahydrofolate cyclohydrolase [Acidovorax temperans].	48.29	292	140	4	1	292	1	281	2e-82	261
tr:H9EX69_MACMU	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:AFE66978.1};	48.66	298	146	3	3	294	51	347	2e-82	264
rs:WP_006455464	methenyltetrahydrofolate cyclohydrolase [Synechococcus sp. PCC 7335].	48.07	285	141	4	3	286	2	280	2e-82	262
rs:WP_038453768	bifunctional protein FolD [Campylobacter fetus].	50.17	287	132	4	4	290	2	277	2e-82	261
rs:WP_015559056	5,10-methylene-tetrahydrofolate dehydrogenase [Ruminococcus champanellensis].	48.97	290	138	2	3	292	2	281	2e-82	262
rs:WP_016763907	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus].	47.24	290	141	4	1	290	1	278	2e-82	261
tr:I9WAK2_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	2e-82	262
rs:WP_006187517	5,10-methylene-tetrahydrofolate dehydrogenase [Treponema vincentii].	46.18	288	150	2	3	290	2	284	2e-82	262
rs:WP_000525718	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	2e-82	262
rs:WP_003079268	5,10-methylene-tetrahydrofolate dehydrogenase [Comamonas testosteroni].	50.17	295	131	5	1	292	1	282	2e-82	261
rs:WP_020278541	5,10-methylene-tetrahydrofolate dehydrogenase [Geobacillus kaustophilus].	48.45	291	139	4	1	291	1	280	3e-82	261
rs:NP_001180836	probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Macaca mulatta].	48.66	298	146	3	3	294	51	347	3e-82	264
rs:XP_011732042	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Macaca nemestrina].	48.32	298	147	3	3	294	12	308	3e-82	262
tr:G1KL48_ANOCA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSACAP00000011168}; Flags: Fragment;	49.83	295	141	4	3	291	5	298	3e-82	262
rs:WP_018990319	5,10-methylene-tetrahydrofolate dehydrogenase [Azoarcus toluclasticus].	47.44	293	147	4	1	293	1	286	3e-82	262
tr:G3T0S3_LOXAF	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLAFP00000006595}; Flags: Fragment;	48.32	298	147	3	3	294	4	300	3e-82	262
rs:WP_014823479	5,10-methylene-tetrahydrofolate dehydrogenase [Solibacillus silvestris].	47.78	293	142	3	1	293	1	282	3e-82	261
rs:WP_028219694	methenyltetrahydrofolate cyclohydrolase [Burkholderia oxyphila].	48.63	292	139	3	3	294	4	284	3e-82	261
rs:WP_022240537	bifunctional protein FolD [Clostridium sp. CAG:413].	48.43	287	137	3	3	289	2	277	3e-82	261
rs:WP_026748039	5,10-methylene-tetrahydrofolate cyclohydrolase [Leptotrichia trevisanii].	46.55	290	143	3	5	293	3	281	3e-82	261
tr:R6NZK5_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.44	289	138	4	3	291	2	279	3e-82	261
rs:WP_035465980	5,10-methylene-tetrahydrofolate cyclohydrolase [Alicyclobacillus pomorum].	50.35	286	130	3	1	286	3	276	3e-82	261
rs:XP_006907721	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Pteropus alecto].	48.32	298	147	3	3	294	78	374	3e-82	265
rs:WP_037224643	5,10-methylene-tetrahydrofolate cyclohydrolase [Richelia intracellularis].	46.67	285	146	2	2	286	5	283	3e-82	262
rs:WP_045675416	methenyltetrahydrofolate cyclohydrolase [Desulfatitalea sp. BRH_c12].	48.31	296	147	2	1	290	1	296	3e-82	262
rs:XP_006059704	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Bubalus bubalis].	48.66	298	146	3	3	294	51	347	3e-82	264
rs:WP_028509900	5,10-methylene-tetrahydrofolate cyclohydrolase [Ruminococcus sp. NK3A76].	49.13	289	136	4	3	291	2	279	3e-82	261
rs:WP_039386708	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria monocytogenes].	48.79	289	137	4	3	291	2	279	3e-82	261
rs:WP_008404240	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus isronensis].	47.78	293	142	3	1	293	1	282	3e-82	261
rs:WP_046782149	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactococcus lactis].	48.79	289	137	3	5	293	3	280	3e-82	261
rs:WP_001950941	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	3e-82	262
tr:X1DDB1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_C02844 {ECO:0000313|EMBL:GAH18786.1}; Flags: Fragment;	47.20	286	144	1	4	289	3	281	3e-82	261
rs:WP_016619088	bifunctional protein FolD [Enterococcus faecalis].	48.61	288	137	4	5	292	4	280	3e-82	261
tr:T1PNE5_MUSDO	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:AFP64224.1};	48.47	295	145	3	3	291	2	295	3e-82	262
rs:WP_035951281	bifunctional protein FolD [Burkholderia multivorans].	48.80	291	138	3	1	291	1	280	3e-82	261
rs:WP_001870966	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	8	285	3e-82	261
rs:WP_005619567	MULTISPECIES: bifunctional protein FolD [Pseudomonas syringae group].	47.24	290	143	2	1	290	1	280	3e-82	261
sp:FOLD_RHOBA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.18	301	141	3	1	290	1	294	3e-82	262
rs:XP_006396261	hypothetical protein EUTSA_v10028771mg [Eutrema salsugineum].	47.42	291	147	2	3	291	60	346	3e-82	264
rs:WP_026920517	methenyltetrahydrofolate cyclohydrolase [Glomeribacter sp. 1016415].	49.66	292	136	4	1	292	1	281	3e-82	261
gpu:CP009506_1098	Methylenetetrahydrofolate dehydrogenase (NADP+) [Methanosarcina siciliae T4/M]	46.26	294	144	3	3	293	8	290	3e-82	261
rs:WP_014535586	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	8	285	3e-82	261
tr:G3WV57_SARHA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSHAP00000019312};	48.66	298	146	3	3	294	41	337	3e-82	263
rs:WP_004518086	5,10-methylene-tetrahydrofolate dehydrogenase [Haloarcula vallismortis].	48.42	285	145	2	4	288	3	285	3e-82	262
rs:WP_008863265	5,10-methylene-tetrahydrofolate dehydrogenase [Parasutterella excrementihominis].	50.00	296	137	3	1	296	1	285	3e-82	261
rs:WP_022767308	5,10-methylene-tetrahydrofolate dehydrogenase [Butyrivibrio sp. NC2007].	49.48	291	134	5	1	289	1	280	3e-82	261
rs:WP_005740067	methenyltetrahydrofolate cyclohydrolase [Pseudomonas amygdali].	47.24	290	143	2	1	290	1	280	3e-82	261
rs:XP_012407409	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Sarcophilus harrisii].	48.66	298	146	3	3	294	18	314	3e-82	262
rs:WP_006671860	5,10-methylene-tetrahydrofolate dehydrogenase [Halobiforma nitratireducens].	47.04	287	150	2	3	289	6	290	3e-82	262
rs:WP_015396987	methylenetetrahydrofolate dehydrogenase [Candidatus Kinetoplastibacterium oncopeltii].	46.76	293	145	3	1	293	1	282	3e-82	261
rs:WP_016835565	5,10-methylene-tetrahydrofolate dehydrogenase [Herbaspirillum lusitanum].	48.29	292	140	3	1	292	1	281	3e-82	261
rs:WP_000525693	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	43.75	288	152	2	5	292	10	287	3e-82	261
rs:XP_011290552	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Musca domestica].	48.98	294	143	3	3	290	43	335	3e-82	263
rs:WP_031408307	methenyltetrahydrofolate cyclohydrolase [Thiomonas sp. FB-Cd].	48.63	292	138	4	1	291	1	281	3e-82	261
tr:J0K936_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	8	285	3e-82	261
rs:WP_012897507	bifunctional protein FolD [Lactococcus lactis].	48.79	289	137	3	5	293	3	280	3e-82	261
rs:WP_021249505	5,10-methylene-tetrahydrofolate dehydrogenase [Thauera terpenica].	48.26	288	142	3	1	288	1	281	3e-82	261
sp:FOLD_DESPS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.08	291	152	1	1	289	1	291	3e-82	262
rs:WP_041235888	5,10-methylene-tetrahydrofolate cyclohydrolase [Dactylococcopsis salina].	48.08	287	141	3	2	286	8	288	3e-82	262
rs:WP_022043518	bifunctional protein FolD [Alistipes finegoldii CAG:68].	50.00	282	132	3	5	286	2	274	3e-82	261
tr:D4JSP8_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.65	286	130	3	5	290	3	274	3e-82	261
rs:WP_028994869	methenyltetrahydrofolate cyclohydrolase [Azonexus hydrophilus].	47.77	291	141	3	1	291	1	280	3e-82	261
rs:WP_037564026	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus agalactiae].	49.31	288	136	2	6	293	5	282	3e-82	261
rs:WP_007336470	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodopirellula baltica].	47.51	301	140	3	1	290	1	294	3e-82	262
tr:I7IK57_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.10	289	139	3	3	291	2	279	3e-82	261
rs:WP_007359624	5,10-methylene-tetrahydrofolate dehydrogenase [Opitutaceae bacterium TAV1].	47.92	288	146	2	4	290	2	286	3e-82	261
rs:XP_012319813	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Aotus nancymaae].	48.99	296	144	3	5	294	11	305	4e-82	262
rs:WP_041513013	methenyltetrahydrofolate cyclohydrolase [Nitrosospira sp. NpAV].	47.32	298	134	4	1	292	1	281	4e-82	261
rs:WP_010274039	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus senegalensis].	48.29	292	140	4	1	292	1	281	4e-82	261
rs:WP_015396265	methylenetetrahydrofolate dehydrogenase [Candidatus Kinetoplastibacterium desouzaii].	46.08	293	147	3	1	293	1	282	4e-82	261
rs:WP_002376153	bifunctional protein FolD [Enterococcus faecalis].	48.26	288	138	4	5	292	4	280	4e-82	261
rs:WP_026435051	methenyltetrahydrofolate cyclohydrolase [Acidovorax sp. JHL-9].	47.30	296	141	5	1	292	1	285	4e-82	261
rs:WP_041744107	methenyltetrahydrofolate cyclohydrolase [Comamonas testosteroni].	49.83	295	132	5	1	292	1	282	4e-82	261
rs:WP_001973147	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	4e-82	261
rs:WP_022534437	5,10-methylene-tetrahydrofolate dehydrogenase [Ralstonia pickettii].	46.58	292	145	3	1	292	1	281	4e-82	261
rs:WP_036572665	5,10-methylene-tetrahydrofolate cyclohydrolase [Oceanobacillus picturae].	48.11	291	138	5	1	290	1	279	4e-82	261
tr:A0A059LRT6_9CHLO	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:KDD76739.1};	46.05	291	151	2	5	293	3	289	4e-82	261
rs:WP_015426154	bifunctional protein FolD [Lactococcus lactis].	48.79	289	137	3	5	293	3	280	4e-82	261
rs:WP_044422524	bifunctional protein FolD [Pseudomonas syringae group genomosp. 3].	47.24	290	143	2	1	290	1	280	4e-82	261
rs:WP_007250317	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae group genomosp. 3].	47.24	290	143	2	1	290	1	280	4e-82	261
rs:XP_001770847	predicted protein [Physcomitrella patens].	46.74	291	149	2	2	290	108	394	4e-82	265
rs:WP_010324846	methenyltetrahydrofolate cyclohydrolase [Marinobacterium stanieri].	49.48	287	135	2	6	292	12	288	4e-82	261
rs:WP_044455398	methenyltetrahydrofolate cyclohydrolase [Pandoraea vervacti].	48.46	293	140	4	1	293	1	282	4e-82	261
rs:WP_006578227	5,10-methylene-tetrahydrofolate dehydrogenase [Cupriavidus sp. HPC(L)].	46.92	292	144	3	1	292	1	281	4e-82	261
rs:WP_022358036	bifunctional protein FolD [Ruminococcus sp. CAG:379].	48.97	290	138	2	3	292	2	281	4e-82	261
rs:WP_015183081	5,10-methylene-tetrahydrofolate dehydrogenase [Microcoleus sp. PCC 7113].	46.55	290	149	2	3	292	6	289	4e-82	261
rs:WP_003036179	tetrahydrofolate dehydrogenase [Streptococcus anginosus].	48.45	291	140	2	3	293	2	282	4e-82	261
rs:WP_017701331	bifunctional protein FolD [Pseudomonas syringae].	47.24	290	143	2	1	290	1	280	4e-82	261
rs:WP_002395763	tetrahydrofolate dehydrogenase [Enterococcus faecalis].	48.26	288	138	4	5	292	4	280	4e-82	261
rs:XP_005555121	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Macaca fascicularis].	48.32	298	147	3	3	294	51	347	4e-82	263
gp:CP000252_1928	methylenetetrahydrofolate dehydrogenase (NADP+) [Syntrophus aciditrophicus SB]	48.63	292	148	2	1	292	32	321	4e-82	262
rs:WP_036099340	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria riparia].	49.83	289	134	4	3	291	2	279	4e-82	261
rs:WP_024902424	methenyltetrahydrofolate cyclohydrolase [Burkholderia andropogonis].	48.45	291	139	3	1	291	1	280	4e-82	261
rs:XP_004152261	PREDICTED: bifunctional protein FolD 2 isoform X1 [Cucumis sativus].	47.10	293	149	2	3	293	9	297	4e-82	261
rs:WP_013293203	5,10-methylene-tetrahydrofolate dehydrogenase [Gallionella capsiferriformans].	48.32	298	129	6	1	291	1	280	4e-82	261
rs:WP_003044302	tetrahydrofolate dehydrogenase [Streptococcus canis].	47.24	290	143	2	4	293	3	282	4e-82	261
tr:A0A098CV28_9LACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.29	292	140	4	2	293	8	288	4e-82	261
rs:WP_027937346	5,10-methylene-tetrahydrofolate cyclohydrolase [Anaeroarcus burkinensis].	47.95	292	140	3	1	290	1	282	4e-82	261
sp:MTD2L_HUMAN	RecName: Full=Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2; AltName: Full=NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein; Short=MTHFD2-like; Includes: RecName: Full=NAD-dependent methylenetetrahydrofolate dehydrogenase; EC=1.5.1.15; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9;	48.99	298	145	3	3	294	51	347	4e-82	263
rs:WP_000525684	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	4e-82	261
rs:XP_004666586	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like, partial [Jaculus jaculus].	48.49	299	147	3	3	295	66	363	4e-82	264
tr:A0A061IPZ9_CRIGR	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:ERE90860.1}; EC=3.5.4.9 {ECO:0000313|EMBL:ERE90860.1};	48.54	309	141	4	3	294	42	349	4e-82	263
rs:WP_039220987	methenyltetrahydrofolate cyclohydrolase [Burkholderia multivorans].	48.63	292	139	3	1	292	1	281	4e-82	261
rs:WP_044321922	bifunctional protein FolD [Pseudomonas amygdali].	47.24	290	143	2	1	290	1	280	4e-82	261
rs:WP_000525694	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	4e-82	261
rs:WP_045850937	5,10-methylene-tetrahydrofolate cyclohydrolase [Domibacillus enclensis].	48.28	290	139	5	1	290	1	279	4e-82	261
rs:WP_028976404	5,10-methylene-tetrahydrofolate cyclohydrolase [Sporolactobacillus terrae].	47.62	294	141	5	1	293	1	282	4e-82	261
rs:WP_039410464	methenyltetrahydrofolate cyclohydrolase [Pandoraea pulmonicola].	48.46	293	140	4	1	293	1	282	4e-82	261
rs:WP_038602888	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactococcus lactis].	48.10	289	139	3	5	293	3	280	4e-82	261
gpu:CP009508_3220	Methylenetetrahydrofolate dehydrogenase (NADP+) [Methanosarcina siciliae C2J]	46.26	294	144	3	3	293	8	290	4e-82	261
rs:WP_009508942	5,10-methylene-tetrahydrofolate dehydrogenase [Opitutaceae bacterium TAV5].	48.25	286	144	2	4	288	2	284	4e-82	261
rs:XP_011990913	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Ovis aries musimon].	49.50	299	143	4	3	294	51	348	4e-82	263
rs:XP_007997076	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Chlorocebus sabaeus].	48.66	298	146	3	3	294	12	308	5e-82	262
sp:FOLD1_PSE14	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.90	290	144	2	1	290	1	280	5e-82	261
rs:WP_019834086	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas sp. PR090111-T3T-6A].	48.66	298	146	3	1	297	1	292	5e-82	261
rs:WP_008488522	methenyltetrahydrofolate cyclohydrolase [Idiomarina xiamenensis].	47.57	288	141	2	1	288	1	278	5e-82	261
rs:WP_015162470	5,10-methylene-tetrahydrofolate dehydrogenase [Chamaesiphon minutus].	48.76	283	140	2	4	286	7	284	5e-82	261
tr:K9YYU6_DACSA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.08	287	141	3	2	286	5	285	5e-82	261
rs:WP_017231574	5,10-methylene-tetrahydrofolate dehydrogenase [Pandoraea sp. B-6].	47.78	293	142	3	1	293	1	282	5e-82	261
rs:WP_026520784	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. VCB2001].	49.48	291	134	5	1	289	1	280	5e-82	261
rs:WP_035961035	methenyltetrahydrofolate cyclohydrolase [Burkholderia grimmiae].	48.95	286	135	3	1	286	1	275	5e-82	261
rs:WP_001966101	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	5e-82	261
rs:WP_047350348	methenyltetrahydrofolate cyclohydrolase [Diaphorobacter sp. J5-51].	49.32	294	133	6	1	291	1	281	5e-82	261
rs:WP_006626247	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Arthrospira].	46.39	291	150	2	3	293	2	286	5e-82	261
rs:XP_002031948	GM26287 [Drosophila sechellia].	46.13	297	153	3	3	293	2	297	5e-82	261
rs:WP_012400869	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia phymatum].	48.97	292	138	3	1	292	1	281	5e-82	261
rs:XP_010652165	PREDICTED: bifunctional protein FolD 2 [Vitis vinifera].	46.76	293	150	2	3	293	9	297	5e-82	261
rs:WP_026801073	5,10-methylene-tetrahydrofolate cyclohydrolase [Pontibacillus halophilus].	45.36	291	148	3	1	291	1	280	5e-82	261
rs:WP_013468684	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter felis].	46.39	291	139	4	5	293	3	278	5e-82	261
tr:J0GHM8_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	8	285	5e-82	261
rs:WP_031765729	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus].	46.21	290	145	3	1	290	1	279	5e-82	261
rs:WP_032100008	5,10-methylene-tetrahydrofolate cyclohydrolase [Anoxybacillus flavithermus].	47.26	292	143	4	1	292	1	281	5e-82	261
rs:WP_035230218	methenyltetrahydrofolate cyclohydrolase [Desulfobulbus sp. Tol-SR].	48.63	292	146	3	1	289	1	291	5e-82	261
rs:WP_039378180	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria monocytogenes].	48.97	292	135	5	3	291	2	282	5e-82	261
rs:WP_033672461	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus gaemokensis].	48.63	292	139	4	1	292	1	281	5e-82	261
rs:WP_010023420	5,10-methylene-tetrahydrofolate dehydrogenase [Sporolactobacillus inulinus].	48.30	294	139	5	1	293	1	282	5e-82	261
rs:XP_001421234	predicted protein [Ostreococcus lucimarinus CCE9901].	47.10	293	149	2	3	293	9	297	5e-82	261
rs:WP_005743880	methenyltetrahydrofolate cyclohydrolase [Pseudomonas amygdali].	46.90	290	144	2	1	290	1	280	5e-82	261
rs:WP_044393743	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus subterraneus].	48.28	290	139	4	1	290	1	279	5e-82	261
tr:H2TLP4_TAKRU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTRUP00000025599};	51.66	302	136	5	3	295	30	330	5e-82	263
rs:WP_016615591	bifunctional protein FolD [Enterococcus faecalis].	48.26	288	138	4	5	292	4	280	5e-82	261
rs:WP_034287926	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter sp. MIT 11-5569].	47.04	287	141	3	4	290	2	277	5e-82	261
tr:I9SN70_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	5e-82	261
rs:WP_010283058	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus timonensis].	48.28	290	139	4	1	290	1	279	5e-82	261
rs:WP_042885035	methenyltetrahydrofolate cyclohydrolase [Cupriavidus necator].	46.58	292	145	3	1	292	1	281	5e-82	261
rs:WP_000525687	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	5e-82	261
rs:WP_031408367	5,10-methylene-tetrahydrofolate cyclohydrolase [Geobacillus vulcani].	48.11	291	140	4	1	291	1	280	5e-82	261
sp:FOLD_DECAR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.14	291	137	3	1	291	1	280	5e-82	261
rs:NP_476930	NAD-dependent methylenetetrahydrofolate dehydrogenase, isoform A [Drosophila melanogaster].	46.46	297	152	3	3	293	2	297	5e-82	261
rs:XP_002104175	GD20823 [Drosophila simulans].	46.13	297	153	3	3	293	2	297	6e-82	261
sp:FOLD_BURCJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.45	291	139	3	1	291	1	280	6e-82	261
rs:WP_006704795	methenyltetrahydrofolate cyclohydrolase [Candidatus Regiella insecticola].	48.11	291	140	2	1	291	1	280	6e-82	261
rs:WP_006039363	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus curdlanolyticus].	47.26	292	143	3	1	292	1	281	6e-82	261
rs:WP_003023701	tetrahydrofolate dehydrogenase [Streptococcus anginosus].	48.80	291	139	3	3	293	2	282	6e-82	261
rs:WP_021052223	5,10-methylene-tetrahydrofolate dehydrogenase [Haloquadratum walsbyi].	49.12	285	141	2	4	288	19	299	6e-82	261
rs:WP_046291614	methenyltetrahydrofolate cyclohydrolase [Pandoraea oxalativorans].	48.12	293	141	4	1	293	1	282	6e-82	261
rs:WP_036062366	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria weihenstephanensis].	49.83	289	134	4	3	291	2	279	6e-82	261
sp:MTDC_DROME	RecName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; Short=DNMDMC; Includes: RecName: Full=NAD-dependent methylenetetrahydrofolate dehydrogenase; EC=1.5.1.15; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Flags: Precursor;	46.46	297	152	3	3	293	8	303	6e-82	261
rs:XP_011732041	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Macaca nemestrina].	48.32	298	147	3	3	294	51	347	6e-82	263
rs:WP_003376260	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.24	290	143	2	1	290	1	280	6e-82	261
rs:WP_002302666	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus mutans].	50.17	291	135	2	3	293	2	282	6e-82	261
rs:WP_034376025	methenyltetrahydrofolate cyclohydrolase [Comamonas testosteroni].	49.83	295	132	5	1	292	1	282	6e-82	261
rs:WP_025948984	5,10-methylene-tetrahydrofolate cyclohydrolase [Geobacillus thermocatenulatus].	48.11	291	140	4	1	291	1	280	6e-82	261
rs:WP_022628390	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus marmarensis].	48.80	291	137	4	1	291	1	279	6e-82	260
tr:D0IVR2_COMT2	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.83	295	132	5	1	292	17	298	6e-82	261
rs:WP_039399049	methenyltetrahydrofolate cyclohydrolase [Pandoraea sputorum].	48.46	293	140	4	1	293	1	282	6e-82	261
rs:WP_014111571	5,10-methylene-tetrahydrofolate dehydrogenase [Taylorella asinigenitalis].	48.10	289	139	3	3	291	2	279	6e-82	261
tr:J0KDA6_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.44	288	150	2	5	292	8	285	6e-82	261
rs:WP_038672090	5,10-methylene-tetrahydrofolate cyclohydrolase [Pelosinus sp. UFO1].	48.45	291	138	3	1	289	1	281	6e-82	261
rs:WP_027320115	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. URHB0009].	46.92	292	144	4	1	292	1	281	6e-82	261
rs:WP_009755026	tetrahydrofolate dehydrogenase [Streptococcus sp. oral taxon 056].	48.10	289	140	3	5	293	3	281	7e-82	260
rs:XP_001758074	predicted protein, partial [Physcomitrella patens].	47.04	287	146	2	6	290	1	283	7e-82	261
rs:WP_033625816	bifunctional protein FolD [Enterococcus faecalis].	48.26	288	138	4	5	292	4	280	7e-82	260
rs:WP_023596508	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pandoraea].	48.46	293	140	4	1	293	1	282	7e-82	261
rs:WP_047206475	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactococcus lactis].	48.44	289	138	3	5	293	3	280	7e-82	261
rs:WP_041639624	5,10-methylene-tetrahydrofolate cyclohydrolase [Trichormus azollae].	47.37	285	144	2	2	286	5	283	7e-82	261
rs:XP_002531873	methylenetetrahydrofolate dehydrogenase, putative [Ricinus communis].	45.73	293	153	2	3	293	9	297	7e-82	261
rs:WP_041967935	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus selenatarsenatis].	47.44	293	143	4	1	293	1	282	7e-82	261
rs:XP_003832373	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Pan paniscus].	49.33	298	144	3	3	294	154	450	7e-82	266
rs:WP_042314646	methenyltetrahydrofolate cyclohydrolase [Burkholderia terrae].	49.32	292	137	4	1	292	1	281	7e-82	261
rs:WP_002552732	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae group genomosp. 2].	47.24	290	143	2	1	290	1	280	7e-82	261
rs:WP_024052840	bifunctional protein FolD [Streptococcus anginosus].	48.80	291	139	3	3	293	2	282	7e-82	261
sp:FOLD_HALWD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.42	285	143	2	4	288	19	299	7e-82	261
rs:WP_008660346	methylenetetrahydrofolate dehydrogenase [Rhodopirellula europaea].	46.84	301	142	3	1	290	1	294	7e-82	261
rs:WP_001927527	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	7e-82	261
rs:WP_018027837	hypothetical protein [Porphyromonas somerae].	47.42	291	153	0	1	291	1	291	7e-82	261
rs:WP_002419352	bifunctional protein FolD [Enterococcus faecalis].	48.26	288	138	4	5	292	4	280	7e-82	260
sp:FOLD_NITEU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.96	296	138	4	1	292	1	281	7e-82	261
tr:A0A060HIF3_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.80	291	135	4	1	289	1	279	7e-82	261
rs:WP_036093982	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria newyorkensis].	49.83	289	134	4	3	291	2	279	7e-82	261
rs:WP_000525686	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.44	288	150	2	5	292	10	287	7e-82	261
rs:WP_007108375	5,10-methylene-tetrahydrofolate dehydrogenase [Natrinema altunense].	46.85	286	150	2	4	289	3	286	7e-82	261
rs:WP_015111576	5,10-methylene-tetrahydrofolate dehydrogenase [Nostoc sp. PCC 7107].	47.02	285	145	2	2	286	5	283	7e-82	261
tr:D7E4F6_NOSA0	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.37	285	144	2	2	286	7	285	7e-82	261
rs:WP_006181699	5,10-methylene-tetrahydrofolate dehydrogenase [Natrinema pellirubrum].	47.20	286	149	2	4	289	3	286	7e-82	261
tr:E4MAR9_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.65	286	135	3	1	286	1	277	7e-82	260
rs:WP_046462449	methenyltetrahydrofolate cyclohydrolase [Comamonas testosteroni].	50.17	295	131	5	1	292	1	282	7e-82	260
rs:WP_002373609	bifunctional protein FolD [Enterococcus faecalis].	48.26	288	138	4	5	292	4	280	8e-82	260
rs:WP_034758030	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus vietnamensis].	46.21	290	145	3	1	290	1	279	8e-82	261
rs:WP_010905592	tetrahydrofolate dehydrogenase [Lactococcus lactis].	48.63	292	139	4	2	293	10	290	8e-82	261
rs:XP_007514818	predicted protein [Bathycoccus prasinos].	46.26	294	151	3	3	293	35	324	8e-82	262
rs:WP_036069605	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria rocourtiae].	49.83	289	134	4	3	291	2	279	8e-82	260
rs:XP_012600241	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Microcebus murinus].	48.32	298	147	3	3	294	20	316	8e-82	261
rs:WP_023365870	hypothetical protein [Spiribacter sp. UAH-SP71].	47.42	291	143	2	1	291	1	281	8e-82	260
rs:WP_027443417	methenyltetrahydrofolate cyclohydrolase [Porphyrobacter cryptus].	48.62	290	145	1	2	291	3	288	8e-82	261
sp:FOLD_METBU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.08	291	143	3	2	292	6	285	8e-82	260
rs:WP_046154526	methenyltetrahydrofolate cyclohydrolase [Burkholderia andropogonis].	48.45	291	139	3	1	291	1	280	8e-82	260
tr:F6HZ29_VITVI	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CCB59944.1};	46.76	293	150	2	3	293	9	297	8e-82	261
rs:WP_014535817	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	8	285	8e-82	261
rs:WP_011121402	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodopirellula baltica].	47.18	301	141	3	1	290	28	321	8e-82	262
rs:WP_008812054	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderiales bacterium 1_1_47].	50.00	296	137	3	1	296	1	285	8e-82	260
rs:WP_022170410	MULTISPECIES: bifunctional protein FolD [Eubacterium].	48.24	284	136	3	6	289	5	277	8e-82	260
rs:WP_016630169	MULTISPECIES: tetrahydrofolate dehydrogenase [Enterococcus].	48.26	288	138	4	5	292	4	280	8e-82	260
rs:WP_009367420	5,10-methylene-tetrahydrofolate dehydrogenase [Halogranum salarium].	49.30	286	141	4	5	289	11	293	8e-82	261
rs:WP_043279841	bifunctional protein FolD [Burkholderia multivorans].	48.80	291	138	3	1	291	1	280	8e-82	260
rs:WP_001918437	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	8e-82	261
rs:WP_017306301	hypothetical protein [Spirulina subsalsa].	46.85	286	147	2	3	288	2	282	8e-82	260
tr:D4MML2_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.65	286	130	3	5	290	3	274	8e-82	260
rs:XP_012383290	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Dasypus novemcinctus].	48.28	290	143	3	11	294	1	289	8e-82	260
sp:FOLD_HYDS0	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.95	292	135	5	4	293	2	278	8e-82	260
rs:WP_010458402	5,10-methylene-tetrahydrofolate dehydrogenase [Acidovorax radicis].	47.60	292	142	3	1	292	1	281	8e-82	260
rs:WP_035770374	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. FCS006].	49.14	291	135	5	1	289	1	280	8e-82	260
rs:WP_046860569	methenyltetrahydrofolate cyclohydrolase [Sedimenticola sp. SIP-G1].	47.92	288	140	2	1	288	1	278	9e-82	260
rs:WP_002409075	tetrahydrofolate dehydrogenase [Enterococcus faecalis].	48.26	288	138	4	5	292	4	280	9e-82	260
tr:V6Z335_STRAG	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.31	288	136	2	6	293	44	321	9e-82	261
rs:XP_010464993	PREDICTED: bifunctional protein FolD 2-like [Camelina sativa].	45.55	292	153	2	2	291	8	295	9e-82	261
rs:XP_006576220	PREDICTED: uncharacterized protein LOC100783652 isoform X1 [Glycine max].	45.73	293	153	2	3	293	2	290	9e-82	261
tr:C0EZ58_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.24	284	136	3	6	289	12	284	9e-82	260
tr:K2AQ13_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.31	290	133	4	5	291	3	281	9e-82	260
rs:WP_045594183	methenyltetrahydrofolate cyclohydrolase [Burkholderia multivorans].	48.80	291	138	3	1	291	1	280	9e-82	260
rs:WP_012306517	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Synechococcus].	45.77	284	149	2	3	286	2	280	9e-82	260
rs:WP_015419487	MULTISPECIES: bifunctional protein FolD [Hydrogenobaculum].	48.29	292	134	5	4	293	2	278	9e-82	260
rs:WP_006830440	5,10-methylene-tetrahydrofolate dehydrogenase [Planococcus antarcticus].	47.10	293	144	3	1	293	1	282	9e-82	260
rs:XP_639248	methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase [Dictyostelium discoideum AX4].	46.60	294	143	4	3	293	8	290	9e-82	260
tr:J9NW23_CANFA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCAFP00000037367};	49.66	290	139	3	11	294	1	289	9e-82	260
rs:WP_021867861	bifunctional protein FolD [Parasutterella excrementihominis CAG:233].	49.66	296	138	3	1	296	1	285	9e-82	260
sp:FOLD_RHOFT	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.93	290	140	4	4	293	8	286	9e-82	260
rs:WP_042733170	methenyltetrahydrofolate cyclohydrolase [Mycoplasma yeatsii].	48.08	287	140	3	5	291	3	280	9e-82	260
rs:WP_037585591	methenyltetrahydrofolate cyclohydrolase [Stenoxybacter acetivorans].	49.66	290	136	2	1	290	1	280	9e-82	260
sp:FOLD_CUPPJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.26	292	143	3	1	292	1	281	9e-82	260
rs:WP_047035440	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus salivarius].	48.46	293	140	3	1	293	1	282	9e-82	260
rs:WP_014568267	tetrahydrofolate dehydrogenase [Lactobacillus salivarius].	48.46	293	140	3	1	293	1	282	1e-81	260
rs:WP_012856640	5,10-methylene-tetrahydrofolate dehydrogenase [Sulfurospirillum deleyianum].	47.55	286	139	3	4	289	2	276	1e-81	260
rs:XP_012579447	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Condylura cristata].	48.97	290	141	3	11	294	1	289	1e-81	260
tr:X0ZQE9_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_C00050 {ECO:0000313|EMBL:GAG62658.1};	47.06	289	146	1	3	291	2	283	1e-81	260
rs:WP_040010070	5,10-methylene-tetrahydrofolate cyclohydrolase [Cylindrospermopsis raciborskii].	47.87	282	141	2	5	286	1	276	1e-81	260
rs:WP_026831057	5,10-methylene-tetrahydrofolate cyclohydrolase [Exiguobacterium antarcticum].	46.90	290	142	3	1	290	1	278	1e-81	260
rs:XP_011939817	PREDICTED: LOW QUALITY PROTEIN: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Cercocebus atys].	50.17	291	138	4	3	291	37	322	1e-81	262
rs:WP_017288401	hypothetical protein [Leptolyngbya boryana].	46.71	289	149	2	3	291	5	288	1e-81	260
rs:XP_007997074	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Chlorocebus sabaeus].	48.66	298	146	3	3	294	51	347	1e-81	262
rs:WP_035790839	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. FC2001].	50.00	286	134	3	4	289	2	278	1e-81	260
rs:XP_008232786	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X2 [Prunus mume].	47.42	291	144	3	3	291	69	352	1e-81	263
rs:XP_006871621	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Chrysochloris asiatica].	48.62	290	142	3	11	294	1	289	1e-81	260
gp:CP000381_98	methylenetetrahydrofolate dehydrogenase/cyclohydrolase [Neisseria meningitidis 053442]	53.12	256	110	2	34	289	2	247	1e-81	259
rs:WP_023082905	FolD 2 [Pseudomonas aeruginosa].	48.80	291	141	3	2	292	3	285	1e-81	261
rs:WP_017302092	hypothetical protein [Nodosilinea nodulosa].	46.71	289	148	2	5	293	4	286	1e-81	260
tr:T1ZWW0_STRAP	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.80	291	139	3	3	293	18	298	1e-81	261
rs:WP_016282935	FolD protein [Lachnospiraceae bacterium A4].	49.82	283	131	3	4	286	3	274	1e-81	260
rs:XP_010242783	PREDICTED: bifunctional protein FolD 2 isoform X1 [Nelumbo nucifera].	45.92	294	153	2	2	293	8	297	1e-81	260
rs:WP_013901187	5,10-methylene-tetrahydrofolate dehydrogenase [Ramlibacter tataouinensis].	48.63	292	139	4	1	292	1	281	1e-81	260
rs:WP_001867411	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	8	285	1e-81	260
rs:WP_038399306	methenyltetrahydrofolate cyclohydrolase [Staphylococcus epidermidis].	46.55	290	144	3	1	290	1	279	1e-81	260
gp:CP003861_1428	methenyltetrahydrofolate cyclohydrolase [Streptococcus anginosus C238]	48.45	291	140	2	3	293	18	298	1e-81	260
rs:WP_036032243	methenyltetrahydrofolate cyclohydrolase [Burkholderia gladioli].	49.65	286	133	4	1	286	1	275	1e-81	260
sp:FOLD_STAES	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.55	290	144	3	1	290	1	279	1e-81	260
rs:WP_001941156	tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	1e-81	260
rs:WP_043734944	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactococcus lactis].	48.44	289	138	3	5	293	3	280	1e-81	260
rs:WP_039940033	5,10-methylene-tetrahydrofolate cyclohydrolase [Alistipes sp. HGB5].	50.00	282	132	3	5	286	2	274	1e-81	260
rs:WP_019291997	tetrahydrofolate dehydrogenase [Lactococcus garvieae].	48.28	290	139	4	4	293	2	280	1e-81	260
rs:WP_017369003	tetrahydrofolate dehydrogenase [Lactococcus garvieae].	48.28	290	139	4	4	293	2	280	1e-81	260
gp:CR522870_1901	probable methylenetetrahydrofolate dehydrogenase [Desulfotalea psychrophila LSv54]	47.08	291	152	1	1	289	18	308	1e-81	261
rs:WP_022099457	bifunctional protein FolD [Proteobacteria bacterium CAG:139].	50.00	296	137	3	1	296	1	285	1e-81	260
rs:XP_010693049	PREDICTED: bifunctional protein FolD 2 [Beta vulgaris subsp. vulgaris].	46.42	293	151	2	3	293	10	298	1e-81	260
rs:WP_010807273	5,10-methylene-tetrahydrofolate dehydrogenase [Pandoraea sp. SD6-2].	47.78	293	142	3	1	293	1	282	1e-81	260
rs:XP_005628393	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Canis lupus familiaris].	49.66	298	143	3	3	294	159	455	1e-81	265
rs:WP_003704074	tetrahydrofolate dehydrogenase [Lactobacillus salivarius].	48.12	293	141	3	1	293	1	282	1e-81	260
gpu:CP009515_750	Methylenetetrahydrofolate dehydrogenase (NADP+) [Methanosarcina lacustris Z-7289]	46.44	295	144	4	2	293	7	290	1e-81	260
rs:WP_041069028	methenyltetrahydrofolate cyclohydrolase [Candidatus Ishikawaella capsulata].	46.55	290	145	3	1	290	1	280	1e-81	260
rs:WP_002456618	bifunctional protein FolD [Staphylococcus epidermidis].	46.55	290	144	3	1	290	1	279	1e-81	260
rs:WP_042534702	5,10-methylene-tetrahydrofolate cyclohydrolase [Oceanobacillus oncorhynchi].	45.86	290	146	3	1	290	1	279	1e-81	260
rs:WP_015128906	5,10-methylene-tetrahydrofolate dehydrogenase [Calothrix sp. PCC 7507].	48.07	285	142	3	2	286	5	283	1e-81	260
rs:WP_006339945	5,10-methylene-tetrahydrofolate dehydrogenase [Parachlamydia acanthamoebae].	47.54	284	143	3	5	286	2	281	1e-81	260
rs:WP_046192033	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. SRS2].	49.48	291	142	2	1	291	1	286	1e-81	260
rs:WP_043586255	methenyltetrahydrofolate cyclohydrolase [Diplosphaera colitermitum].	47.90	286	145	2	4	288	2	284	1e-81	260
rs:XP_008368978	PREDICTED: bifunctional protein FolD 2 [Malus domestica].	45.73	293	153	2	3	293	9	297	1e-81	260
rs:WP_046447530	methenyltetrahydrofolate cyclohydrolase [Acinetobacter sp. N54.MGS-139].	50.00	296	137	3	1	296	1	285	1e-81	260
sp:FOLD_CUPTR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.92	292	144	3	1	292	1	281	1e-81	259
rs:WP_026828909	5,10-methylene-tetrahydrofolate cyclohydrolase [Exiguobacterium sibiricum].	47.24	290	141	3	1	290	1	278	1e-81	259
rs:WP_017796994	5,10-methylene-tetrahydrofolate dehydrogenase [Oceanobacillus kimchii].	47.55	286	139	3	5	290	4	278	1e-81	260
sp:FOLD_LACS1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.81	293	139	3	1	293	1	282	1e-81	260
rs:XP_012319812	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Aotus nancymaae].	48.99	296	144	3	5	294	53	347	1e-81	262
rs:WP_034207764	methenyltetrahydrofolate cyclohydrolase [Burkholderia cepacia].	48.45	291	139	3	1	291	1	280	1e-81	260
rs:WP_027706139	methenyltetrahydrofolate cyclohydrolase [Zymobacter palmae].	49.66	290	136	2	1	290	1	280	1e-81	259
rs:WP_029935305	methenyltetrahydrofolate cyclohydrolase [Thiomicrospira pelophila].	46.55	290	145	2	1	290	1	280	1e-81	259
tr:S6FRV6_LACLL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.63	292	139	4	2	293	10	290	1e-81	260
sp:FOLD_LACLA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.79	289	137	4	5	293	3	280	1e-81	259
rs:WP_000525697	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	44.10	288	151	2	5	292	10	287	1e-81	260
rs:WP_006091530	5,10-methylene-tetrahydrofolate dehydrogenase [Natronorubrum tibetense].	46.15	286	152	2	4	289	3	286	1e-81	260
rs:WP_039006475	methenyltetrahydrofolate cyclohydrolase [Cupriavidus sp. IDO].	46.58	292	145	3	1	292	1	281	1e-81	259
rs:WP_012820583	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Geobacillus].	48.45	291	139	4	1	291	1	280	1e-81	259
rs:XP_003057564	predicted protein [Micromonas pusilla CCMP1545].	44.71	293	156	2	3	293	8	296	1e-81	260
tr:J0B5M9_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.10	288	151	2	5	292	8	285	1e-81	260
rs:WP_008459109	5,10-methylene-tetrahydrofolate dehydrogenase [Natrinema gari].	46.85	286	150	2	4	289	3	286	1e-81	260
rs:WP_014667578	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter cinaedi].	48.42	285	136	4	5	289	3	276	1e-81	259
tr:C2EEM3_9LACO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.81	293	139	3	1	293	8	289	1e-81	260
rs:WP_025799639	5,10-methylene-tetrahydrofolate cyclohydrolase [Prevotella saccharolytica].	46.74	291	154	1	4	294	2	291	1e-81	260
rs:WP_033899233	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactococcus lactis].	48.44	289	138	3	5	293	3	280	1e-81	259
rs:WP_028789983	5,10-methylene-tetrahydrofolate cyclohydrolase [Tetragenococcus muriaticus].	46.58	292	145	4	3	294	2	282	1e-81	259
sp:FOLD_STAEQ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.21	290	145	3	1	290	1	279	2e-81	259
rs:WP_008943847	5,10-methylene-tetrahydrofolate dehydrogenase [Oceanibaculum indicum].	49.82	285	137	2	5	289	7	285	2e-81	260
rs:WP_013313779	5,10-methylene-tetrahydrofolate dehydrogenase [Spirochaeta thermophila].	47.93	290	150	1	1	290	1	289	2e-81	260
rs:XP_005333301	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Ictidomys tridecemlineatus].	48.66	298	146	3	3	294	51	347	2e-81	262
sp:MTD2L_RAT	RecName: Full=Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2; AltName: Full=NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein; Short=MTHFD2-like; Includes: RecName: Full=NAD-dependent methylenetetrahydrofolate dehydrogenase; EC=1.5.1.15; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9;	48.66	298	146	3	3	294	42	338	2e-81	261
rs:WP_012910794	5,10-methylene-tetrahydrofolate dehydrogenase [Pirellula staleyi].	45.97	298	149	2	1	293	1	291	2e-81	260
rs:XP_007050860	Amino acid dehydrogenase family protein [Theobroma cacao].	46.42	293	151	2	3	293	9	297	2e-81	260
tr:A0A0A0MY28_RAT	SubName: Full=Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|Ensembl:ENSRNOP00000044342};	48.66	298	146	3	3	294	42	338	2e-81	261
rs:WP_034982366	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus salivarius].	48.81	293	139	3	1	293	1	282	2e-81	259
rs:WP_009768825	5,10-methylene-tetrahydrofolate dehydrogenase [Oscillatoriales cyanobacterium JSC-12].	47.02	285	145	2	2	286	5	283	2e-81	260
rs:WP_014413364	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodospirillum photometricum].	50.17	293	135	3	1	290	1	285	2e-81	259
rs:WP_008906934	5,10-methylene-tetrahydrofolate dehydrogenase [Acidovorax sp. NO-1].	48.29	292	140	4	1	292	1	281	2e-81	259
rs:WP_015790666	5,10-methylene-tetrahydrofolate dehydrogenase [Halorhabdus utahensis].	47.74	287	148	2	3	289	2	286	2e-81	260
rs:WP_013880628	5,10-methylene-tetrahydrofolate dehydrogenase [Halopiger xanaduensis].	47.55	286	148	2	4	289	3	286	2e-81	260
sp:FOLD_THEYD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.21	290	145	3	1	290	1	279	2e-81	259
rs:WP_002363394	tetrahydrofolate dehydrogenase [Enterococcus faecalis].	48.26	288	138	4	5	292	4	280	2e-81	259
tr:N6TDW5_DENPD	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ENN75943.1, ECO:0000313|EnsemblMetazoa:ENN75943}; Flags: Fragment;	47.18	301	151	3	2	296	16	314	2e-81	261
rs:WP_036202049	5,10-methylene-tetrahydrofolate cyclohydrolase [Lysinibacillus sinduriensis].	47.60	292	142	4	2	293	3	283	2e-81	259
rs:XP_004392972	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Odobenus rosmarus divergens].	48.66	298	146	3	3	294	50	346	2e-81	261
tr:S9YJ87_9CETA	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:EPY87371.1};	48.11	291	116	3	3	291	41	298	2e-81	261
sp:FOLD_LISW6	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	289	133	4	3	291	2	279	2e-81	259
rs:WP_025288055	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori].	43.75	288	152	2	5	292	8	285	2e-81	259
rs:WP_036097292	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria floridensis].	49.65	288	134	4	3	290	2	278	2e-81	259
rs:XP_012660828	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Otolemur garnettii].	48.62	290	142	3	11	294	1	289	2e-81	259
rs:WP_029998491	hypothetical protein [Marinimicrobia bacterium SCGC AAA003-L08].	46.05	291	155	2	1	291	1	289	2e-81	259
rs:WP_046436004	5,10-methylene-tetrahydrofolate cyclohydrolase [Ruminococcus sp. UNK.MGS-30].	47.22	288	142	3	3	290	2	279	2e-81	259
rs:WP_002657953	5,10-methylene-tetrahydrofolate dehydrogenase [Saprospira grandis].	44.60	287	159	0	4	290	2	288	2e-81	260
sp:FOLD_GLOVI	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.30	294	145	3	1	293	1	288	2e-81	259
rs:XP_005608770	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Equus caballus].	47.65	298	149	3	3	294	20	316	2e-81	260
rs:WP_007808867	methenyltetrahydrofolate cyclohydrolase [Rhodanobacter spathiphylli].	50.00	286	133	2	1	286	1	276	2e-81	259
rs:XP_004290770	PREDICTED: bifunctional protein FolD 2 [Fragaria vesca subsp. vesca].	46.76	293	150	2	3	293	9	297	2e-81	260
gp:CP006822_494	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pylori oki128]	43.75	288	152	2	5	292	15	292	2e-81	260
rs:WP_009569158	tetrahydrofolate dehydrogenase [Streptococcus intermedius].	48.28	290	140	2	4	293	3	282	2e-81	259
rs:WP_044730875	5,10-methylene-tetrahydrofolate cyclohydrolase [Geobacillus kaustophilus].	47.77	291	141	4	1	291	1	280	2e-81	259
rs:WP_014556442	5,10-methylene-tetrahydrofolate dehydrogenase [Haloquadratum walsbyi].	48.42	285	143	2	4	288	19	299	2e-81	260
rs:WP_021903284	bifunctional protein FolD [Porphyromonas sp. CAG:1061].	47.08	291	154	0	1	291	1	291	2e-81	260
rs:WP_028358051	methenyltetrahydrofolate cyclohydrolase [Brackiella oedipodis].	47.06	289	142	3	1	289	1	278	2e-81	259
rs:WP_002863158	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Campylobacter jejuni].	54.12	255	106	3	40	293	1	245	2e-81	258
rs:WP_012959651	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus pseudofirmus].	48.80	291	137	4	1	291	1	279	2e-81	259
rs:WP_006355597	5,10-methylene-tetrahydrofolate dehydrogenase [[Clostridium] methylpentosum].	48.61	288	137	4	3	290	2	278	2e-81	259
tr:D4J8Q1_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.26	288	138	3	3	290	2	278	2e-81	259
sp:FOLD_ACIAC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.60	292	142	4	1	292	1	281	2e-81	259
rs:WP_021911411	bifunctional protein FolD [Eubacterium sp. CAG:786].	50.17	291	129	4	1	290	1	276	2e-81	259
rs:XP_010498863	PREDICTED: bifunctional protein FolD 2 [Camelina sativa].	45.21	292	154	2	2	291	8	295	2e-81	259
rs:WP_027008688	methenyltetrahydrofolate cyclohydrolase [Conchiformibius kuhniae].	48.80	291	139	2	1	291	1	281	2e-81	259
rs:WP_004241000	MULTISPECIES: methylenetetrahydrofolate dehydrogenase [Morganella].	48.11	291	141	3	1	291	1	281	2e-81	259
rs:XP_008991429	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Callithrix jacchus].	48.32	298	147	3	3	294	10	306	2e-81	260
rs:WP_006832604	5,10-methylene-tetrahydrofolate dehydrogenase [Erythrobacter sp. SD-21].	48.63	292	146	1	1	292	1	288	2e-81	259
rs:WP_028129245	5,10-methylene-tetrahydrofolate cyclohydrolase [Selenomonas sp. AE3005].	48.29	292	139	3	1	290	1	282	2e-81	259
rs:WP_041901361	hypothetical protein [Marinimicrobia bacterium SCGC AAA160-B08].	47.59	290	147	4	1	290	1	285	2e-81	259
rs:WP_018366875	tetrahydrofolate dehydrogenase [Streptococcus didelphis].	47.77	291	142	3	3	293	2	282	2e-81	259
rs:WP_024005791	5,10-methylene-tetrahydrofolate dehydrogenase [Advenella kashmirensis].	47.26	292	143	4	1	292	1	281	2e-81	259
rs:XP_007179894	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Balaenoptera acutorostrata scammoni].	48.32	298	147	3	3	294	51	347	2e-81	261
tr:B9BDP1_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.80	291	138	3	1	291	46	325	2e-81	261
rs:WP_025873335	5,10-methylene-tetrahydrofolate cyclohydrolase [Enterococcus sp. TR].	47.93	290	140	4	3	292	2	280	2e-81	259
tr:H2V0N0_TAKRU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTRUP00000042760};	47.32	298	150	3	2	293	31	327	2e-81	261
rs:WP_029279789	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus].	47.60	292	142	4	1	292	1	281	2e-81	259
tr:A0A0B8QYA6_LACLL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.63	292	139	4	2	293	10	290	2e-81	259
rs:WP_002396478	tetrahydrofolate dehydrogenase [Enterococcus faecalis].	48.26	288	138	4	5	292	4	280	2e-81	259
rs:WP_010825792	FolD protein [Enterococcus faecalis].	48.26	288	138	4	5	292	4	280	2e-81	259
rs:WP_002450720	MULTISPECIES: tetrahydrofolate dehydrogenase [Staphylococcus].	46.90	290	143	3	1	290	1	279	2e-81	259
rs:XP_011895834	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X6 [Cercocebus atys].	48.97	290	141	3	11	294	1	289	2e-81	259
rs:XP_005707916	bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / 5,10-methenyltetrahydrofolate cyclohydrolase [Galdieria sulphuraria].	44.71	293	156	2	3	293	2	290	3e-81	259
rs:WP_027784875	methenyltetrahydrofolate cyclohydrolase [Burkholderia cepacia].	48.11	291	140	3	1	291	1	280	3e-81	259
rs:WP_009161729	tetrahydrofolate dehydrogenase [Prevotella saccharolytica].	46.74	291	154	1	4	294	2	291	3e-81	259
tr:A0A0C9NMS0_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.48	297	146	2	1	290	1	297	3e-81	259
sp:FOLD_DICNV	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.81	293	138	4	1	290	1	284	3e-81	259
rs:WP_039374705	methenyltetrahydrofolate cyclohydrolase [Pandoraea pnomenusa].	47.78	293	142	3	1	293	1	282	3e-81	259
rs:WP_020587508	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfobacter curvatus].	48.47	295	150	1	1	293	1	295	3e-81	259
rs:XP_004419230	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Ceratotherium simum simum].	47.65	298	149	3	3	294	51	347	3e-81	261
rs:WP_018376521	tetrahydrofolate dehydrogenase [Streptococcus orisratti].	47.57	288	141	2	6	293	5	282	3e-81	259
rs:WP_007313841	5,10-methylene-tetrahydrofolate dehydrogenase [Methanolinea tarda].	47.90	286	134	4	5	290	2	272	3e-81	259
gp:CP002421_90	methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase [Neisseria meningitidis M01-240149]	53.12	256	110	2	34	289	2	247	3e-81	258
tr:J0IW70_HELPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.40	288	153	2	5	292	8	285	3e-81	259
rs:WP_010125642	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas sp. KC8].	49.48	291	142	2	1	291	1	286	3e-81	259
rs:WP_004427905	methylenetetrahydrofolate dehydrogenase [Mycoplasma yeatsii].	47.74	287	141	3	5	291	3	280	3e-81	259
rs:WP_003394139	5,10-methylene-tetrahydrofolate dehydrogenase [Anoxybacillus flavithermus].	47.26	292	143	4	1	292	1	281	3e-81	259
rs:XP_001359830	GA14943 [Drosophila pseudoobscura pseudoobscura].	45.86	290	150	3	3	286	2	290	3e-81	259
rs:WP_026019026	5,10-methylene-tetrahydrofolate cyclohydrolase [Ureibacillus thermosphaericus].	47.10	293	144	3	1	293	1	282	3e-81	259
rs:XP_007495732	PREDICTED: LOW QUALITY PROTEIN: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Monodelphis domestica].	48.32	298	147	3	3	294	41	337	3e-81	261
rs:WP_017864359	tetrahydrofolate dehydrogenase [Lactococcus lactis].	48.44	289	138	3	5	293	3	280	3e-81	259
rs:WP_003077021	tetrahydrofolate dehydrogenase [Streptococcus intermedius].	48.28	290	140	2	4	293	3	282	3e-81	259
rs:WP_003055356	5,10-methylene-tetrahydrofolate dehydrogenase [Comamonas testosteroni].	49.49	295	133	5	1	292	1	282	3e-81	259
rs:WP_007195667	methenyltetrahydrofolate cyclohydrolase [Thiocapsa marina].	50.00	290	135	2	1	290	1	280	3e-81	259
rs:XP_009779718	PREDICTED: bifunctional protein FolD 2-like [Nicotiana sylvestris].	46.42	293	151	2	3	293	9	297	3e-81	259
rs:WP_021040409	5,10-methylene-tetrahydrofolate dehydrogenase [Halonotius sp. J07HN4].	49.30	286	143	2	4	289	3	286	3e-81	259
rs:WP_005532965	5,10-methylene-tetrahydrofolate dehydrogenase [Haloarcula argentinensis].	47.55	286	148	2	5	290	4	287	3e-81	259
rs:WP_028322071	methenyltetrahydrofolate cyclohydrolase [Desulfatiglans anilini].	47.30	296	150	2	1	290	1	296	3e-81	259
rs:WP_019490811	methenyltetrahydrofolate cyclohydrolase [Calothrix sp. PCC 7103].	46.23	292	151	2	2	293	5	290	3e-81	259
rs:WP_019321915	tetrahydrofolate dehydrogenase [Streptococcus mutans].	50.00	290	135	2	4	293	3	282	3e-81	259
tr:W1FW27_ECOLX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	52.67	262	114	3	28	289	10	261	3e-81	258
rs:WP_026563639	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. UNC41MFS5].	49.83	293	136	4	1	293	1	282	3e-81	259
tr:A0A0A0KWH1_CUCSA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGN52787.1};	47.10	293	149	2	3	293	83	371	3e-81	262
rs:XP_010340901	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Saimiri boliviensis boliviensis].	47.99	298	148	3	3	294	23	319	3e-81	260
rs:WP_005355345	5,10-methylene-tetrahydrofolate dehydrogenase [[Eubacterium] siraeum].	49.30	286	131	3	5	290	3	274	3e-81	259
rs:WP_026694683	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus kribbensis].	48.97	290	137	4	1	290	1	279	3e-81	259
tr:A0A0D9QXH6_CHLSB	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAP00000001065};	48.66	298	146	3	3	294	90	386	3e-81	262
rs:WP_008809090	tetrahydrofolate dehydrogenase [Streptococcus sp. 2_1_36FAA].	47.77	291	142	3	3	293	2	282	3e-81	259
rs:WP_035546519	methenyltetrahydrofolate cyclohydrolase [Burkholderia sp. 9120].	50.00	286	132	4	1	286	1	275	3e-81	259
rs:XP_010486927	PREDICTED: bifunctional protein FolD 2-like [Camelina sativa].	45.21	292	154	2	2	291	8	295	3e-81	259
rs:WP_006075678	methylenetetrahydrofolate dehydrogenase, partial [Vibrio shilonii].	50.00	270	125	2	1	270	1	260	3e-81	258
rs:WP_010775183	FolD protein [Enterococcus faecalis].	48.26	288	138	4	5	292	4	280	3e-81	259
rs:WP_003071966	tetrahydrofolate dehydrogenase [Streptococcus intermedius].	48.28	290	140	2	4	293	3	282	3e-81	259
rs:WP_002474580	tetrahydrofolate dehydrogenase [Staphylococcus epidermidis].	46.21	290	145	3	1	290	1	279	4e-81	259
rs:WP_000525717	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter pylori].	43.40	288	153	2	5	292	10	287	4e-81	259
rs:WP_019241324	hypothetical protein [Bacillus massilioanorexius].	48.28	290	139	4	1	290	1	279	4e-81	259
sp:FOLD_CUPNH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.23	292	146	3	1	292	1	281	4e-81	258
rs:WP_020254641	hypothetical protein [Parcubacteria bacterium SCGC AAA036-E14].	47.18	284	135	3	5	288	4	272	4e-81	258
rs:WP_021857312	bifunctional protein FolD [Firmicutes bacterium CAG:555].	48.44	289	136	4	3	291	2	277	4e-81	258
rs:WP_020680803	methenyltetrahydrofolate cyclohydrolase [Marinobacterium rhizophilum].	50.53	285	131	3	6	290	12	286	4e-81	259
tr:A0A0B5GZR0_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.78	287	143	4	5	290	4	287	4e-81	259
rs:XP_008991428	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Callithrix jacchus].	48.32	298	147	3	3	294	23	319	4e-81	260
rs:WP_007012362	5,10-methylene-tetrahydrofolate dehydrogenase [Novosphingobium pentaromativorans].	50.17	291	138	3	3	292	4	288	4e-81	259
rs:WP_022774729	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Symbiobacter mobilis].	46.58	292	145	4	2	293	7	287	4e-81	259
rs:WP_036824251	5,10-methylene-tetrahydrofolate cyclohydrolase [Pontibacillus yanchengensis].	45.36	291	148	3	1	291	1	280	4e-81	258
rs:XP_002439291	hypothetical protein SORBIDRAFT_09g003920 [Sorghum bicolor].	47.10	293	149	2	3	293	2	290	4e-81	259
rs:WP_024732444	methenyltetrahydrofolate cyclohydrolase [Clostridiales bacterium VE202-14].	47.40	289	141	4	3	291	2	279	4e-81	258
rs:WP_021028068	5,10-methylene-tetrahydrofolate dehydrogenase [Comamonas sp. B-9].	49.49	295	133	5	1	292	1	282	4e-81	258
sp:FOLD1_GEOMG	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.60	292	145	3	4	293	2	287	4e-81	259
rs:WP_036621083	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus alvei].	48.45	291	139	4	1	291	1	280	4e-81	259
rs:WP_018703379	hypothetical protein [Anaeromusa acidaminophila].	47.95	292	140	3	1	290	1	282	4e-81	258
tr:K0AB69_EXIAB	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.88	288	141	3	3	290	2	277	4e-81	258
rs:WP_025389469	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	48.98	294	142	3	1	294	1	286	4e-81	259
rs:WP_035785278	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. XPD2002].	49.65	286	135	3	4	289	2	278	4e-81	258
rs:WP_014031212	5,10-methylene-tetrahydrofolate dehydrogenase [Haloarcula hispanica].	48.78	287	143	4	5	290	4	287	4e-81	259
gp:DRONMDMC_1	NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase [Drosophila melanogaster]	46.46	297	152	3	3	293	56	351	4e-81	261
rs:WP_035398707	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Exiguobacterium].	46.90	290	142	3	1	290	1	278	4e-81	258
rs:WP_010631969	5,10-methylene-tetrahydrofolate dehydrogenase [Sporolactobacillus vineae].	47.78	293	142	4	1	293	1	282	4e-81	259
gp:HE774679_2416	methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase [Bacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2]	47.99	273	131	4	21	293	3	264	4e-81	258
rs:WP_014079713	5,10-methylene-tetrahydrofolate dehydrogenase [Roseburia hominis].	50.18	283	130	4	4	286	3	274	4e-81	258
rs:XP_008800846	PREDICTED: bifunctional protein FolD 2 [Phoenix dactylifera].	46.08	293	152	2	3	293	2	290	4e-81	259
tr:D0QWP2_DROMI	SubName: Full=GA14943 {ECO:0000313|EMBL:ACN94741.1};	45.86	290	150	3	3	286	2	290	4e-81	259
rs:WP_045874089	5,10-methylene-tetrahydrofolate cyclohydrolase [Tolypothrix sp. PCC 7601].	48.07	285	142	2	2	286	5	283	4e-81	259
rs:WP_008429971	5,10-methylene-tetrahydrofolate dehydrogenase [Planococcus donghaensis].	48.45	291	139	4	1	291	1	280	4e-81	258
rs:WP_031808464	methenyltetrahydrofolate cyclohydrolase, partial [Staphylococcus aureus].	45.86	290	146	3	1	290	1	279	4e-81	258
rs:WP_015199070	5,10-methylene-tetrahydrofolate dehydrogenase [Calothrix parietina].	46.67	285	146	2	2	286	5	283	4e-81	259
rs:WP_026558854	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. J37].	46.76	293	145	4	1	293	1	282	4e-81	258
rs:WP_019320478	tetrahydrofolate dehydrogenase [Streptococcus mutans].	49.66	290	136	2	4	293	3	282	4e-81	258
tr:U3EL33_CALJA	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:JAB26291.1};	48.32	298	147	3	3	294	51	347	4e-81	261
rs:WP_044470147	methenyltetrahydrofolate cyclohydrolase [Mannheimia sp. MG13].	48.31	296	143	2	1	296	1	286	4e-81	258
rs:WP_038210235	methenyltetrahydrofolate cyclohydrolase [Xenophilus azovorans].	48.29	292	140	3	1	292	1	281	5e-81	258
tr:H2V0M9_TAKRU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTRUP00000042759};	47.32	298	150	3	2	293	28	324	5e-81	260
rs:WP_041261851	5,10-methylene-tetrahydrofolate cyclohydrolase [Exiguobacterium sibiricum].	47.24	290	141	3	1	290	1	278	5e-81	258
rs:XP_011614117	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Takifugu rubripes].	47.16	299	151	3	2	294	50	347	5e-81	261
rs:WP_031887364	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus].	45.86	290	146	3	1	290	1	279	5e-81	258
rs:WP_029055544	methenyltetrahydrofolate cyclohydrolase [Staphylococcus sp. URHA0057].	46.21	290	145	3	1	290	1	279	5e-81	258
rs:WP_020084095	5,10-methylene-tetrahydrofolate dehydrogenase [Hyphomicrobium zavarzinii].	48.62	290	143	2	1	290	1	284	5e-81	258
rs:XP_003554514	PREDICTED: bifunctional protein FolD 2-like [Glycine max].	45.39	293	154	2	3	293	2	290	5e-81	259
rs:WP_028586238	methenyltetrahydrofolate cyclohydrolase [Desulfocurvus vexinensis].	48.60	286	138	3	5	288	3	281	5e-81	258
rs:WP_002278063	tetrahydrofolate dehydrogenase [Streptococcus mutans].	49.66	290	136	2	4	293	3	282	5e-81	258
rs:XP_002941814	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Xenopus (Silurana) tropicalis].	48.66	298	146	4	3	294	57	353	5e-81	261
rs:WP_020071740	5,10-methylene-tetrahydrofolate dehydrogenase [[Clostridium] sporosphaeroides].	48.44	289	139	3	3	291	2	280	5e-81	258
rs:WP_040735927	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus alvei].	48.80	291	138	4	1	291	1	280	5e-81	258
rs:WP_046893234	methenyltetrahydrofolate cyclohydrolase [Morganella morganii].	47.77	291	142	3	1	291	1	281	5e-81	258
tr:G9KBN7_MUSPF	SubName: Full=Methylenetetrahydrofolate dehydrogenase 2-like protein {ECO:0000313|EMBL:AES02312.1}; Flags: Fragment;	48.82	297	145	3	3	293	3	298	5e-81	259
sp:FOLD_PSYIN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.77	291	142	2	1	291	1	281	5e-81	258
tr:U1PAY1_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.60	286	145	2	3	288	2	285	5e-81	259
rs:WP_023189853	methylenetetrahydrofolate dehydrogenase [Lactococcus lactis].	48.44	289	138	3	5	293	3	280	5e-81	258
rs:WP_018358263	hypothetical protein [Porphyromonas levii].	47.08	291	154	0	1	291	1	291	5e-81	259
rs:WP_004258657	tetrahydrofolate dehydrogenase [Lactococcus garvieae].	48.28	290	139	4	4	293	2	280	5e-81	258
sp:FOLD_STAA1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.86	290	146	3	1	290	1	279	5e-81	258
rs:WP_019313873	tetrahydrofolate dehydrogenase [Streptococcus mutans].	49.66	290	136	2	4	293	3	282	5e-81	258
tr:W1H5G6_KLEPN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	52.69	260	113	3	32	291	6	255	5e-81	258
rs:WP_023627380	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus].	46.76	293	145	4	1	293	1	282	5e-81	258
rs:WP_039288195	methenyltetrahydrofolate cyclohydrolase [Novosphingobium malaysiense].	48.28	290	146	1	3	292	4	289	6e-81	259
rs:WP_042115560	methenyltetrahydrofolate cyclohydrolase [Pandoraea apista].	47.78	293	142	4	1	293	1	282	6e-81	258
rs:WP_004074414	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfobacter postgatei].	47.80	295	152	1	1	293	1	295	6e-81	259
rs:WP_031423334	bifunctional protein FolD [Exiguobacterium sp. NG55].	49.13	289	134	4	3	291	2	277	6e-81	258
rs:WP_045535479	methenyltetrahydrofolate cyclohydrolase [Comamonadaceae bacterium B1].	48.25	286	137	3	1	286	1	275	6e-81	258
rs:XP_008286352	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Stegastes partitus].	46.82	299	152	3	2	294	7	304	6e-81	259
rs:XP_008265974	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Oryctolagus cuniculus].	46.64	298	152	3	3	294	42	338	6e-81	260
rs:XP_008235037	PREDICTED: bifunctional protein FolD 2-like [Prunus mume].	45.73	293	153	2	3	293	9	297	6e-81	259
rs:WP_031825996	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus].	45.86	290	146	3	1	290	1	279	6e-81	258
rs:WP_013522533	5,10-methylene-tetrahydrofolate dehydrogenase [Taylorella equigenitalis].	48.26	288	138	3	4	291	3	279	6e-81	258
rs:WP_026766532	5,10-methylene-tetrahydrofolate cyclohydrolase [Selenomonas ruminantium].	47.60	292	141	3	1	290	1	282	6e-81	258
rs:WP_024569442	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Cupriavidus].	47.77	291	141	3	1	291	1	280	6e-81	258
rs:WP_041067234	5,10-methylene-tetrahydrofolate cyclohydrolase [Cohnella sp. VKM B-2846].	48.61	288	137	3	6	293	1	277	6e-81	258
rs:WP_039889034	5,10-methylene-tetrahydrofolate cyclohydrolase [Leptotrichia hofstadii].	46.21	290	144	3	5	293	3	281	6e-81	258
rs:WP_045707843	methenyltetrahydrofolate cyclohydrolase [Desulfobulbaceae bacterium BRH_c16a].	47.46	295	153	1	1	293	1	295	6e-81	258
rs:WP_019978962	hypothetical protein [Verrucomicrobia bacterium SCGC AAA300-O17].	46.05	291	153	2	4	293	2	289	6e-81	258
rs:WP_022763761	5,10-methylene-tetrahydrofolate dehydrogenase [Butyrivibrio sp. XPD2006].	49.48	291	134	4	1	289	1	280	6e-81	258
rs:WP_002275379	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus mutans].	49.66	290	136	2	4	293	3	282	6e-81	258
sp:FOLD_STRMU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.66	290	136	2	4	293	3	282	6e-81	258
rs:WP_026217389	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus ovis].	48.46	293	141	3	1	293	1	283	6e-81	258
rs:XP_009621984	PREDICTED: bifunctional protein FolD 2 isoform X1 [Nicotiana tomentosiformis].	46.42	293	151	2	3	293	9	297	6e-81	259
rs:WP_002907036	bifunctional protein FolD [Streptococcus sanguinis].	47.42	291	143	3	3	293	2	282	6e-81	258
rs:WP_035531068	methenyltetrahydrofolate cyclohydrolase [Burkholderia sacchari].	48.29	292	140	4	1	292	1	281	6e-81	258
rs:WP_016291047	FolD protein [Lachnospiraceae bacterium 28-4].	51.06	284	128	3	3	286	2	274	7e-81	258
rs:WP_036830862	5,10-methylene-tetrahydrofolate cyclohydrolase [Pontibacillus litoralis].	46.39	291	145	3	1	291	1	280	7e-81	258
rs:XP_007163092	hypothetical protein PHAVU_001G205500g [Phaseolus vulgaris].	45.73	293	153	2	3	293	2	290	7e-81	258
rs:WP_026745774	5,10-methylene-tetrahydrofolate cyclohydrolase [Leptotrichia hofstadii].	46.21	290	144	3	5	293	3	281	7e-81	258
rs:WP_012777584	methenyltetrahydrofolate cyclohydrolase [Methylotenera mobilis].	46.23	292	147	2	1	292	1	282	7e-81	258
rs:WP_017922994	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia glumae].	49.30	286	134	4	1	286	1	275	7e-81	258
sp:FOLD_VESOH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.28	290	136	3	4	293	2	277	7e-81	258
rs:WP_022047057	bifunctional protein FolD [Roseburia sp. CAG:18].	49.31	288	135	3	3	290	2	278	7e-81	258
tr:F6Q8U4_MACMU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000020400};	48.62	290	142	3	11	294	1	289	7e-81	258
rs:WP_007584020	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia].	48.97	292	138	4	1	292	1	281	7e-81	258
rs:WP_015409974	methylenetetrahydrofolate dehydrogenase [Natronomonas moolapensis].	49.48	287	141	4	4	289	3	286	7e-81	258
rs:WP_017653227	methenyltetrahydrofolate cyclohydrolase [Microchaete sp. PCC 7126].	46.67	285	146	2	2	286	5	283	7e-81	258
rs:WP_045138023	methenyltetrahydrofolate cyclohydrolase [Morganella morganii].	47.62	294	144	3	1	294	1	284	7e-81	258
rs:WP_003864369	5,10-methylene-tetrahydrofolate dehydrogenase [Holdemanella biformis].	48.97	290	132	4	4	290	2	278	7e-81	258
rs:WP_008588916	5,10-methylene-tetrahydrofolate dehydrogenase [Salimicrobium jeotgali].	45.70	291	146	3	1	291	1	279	7e-81	258
rs:WP_010771226	FolD protein [Enterococcus caccae].	47.24	290	142	4	3	292	2	280	7e-81	258
rs:WP_029095501	methenyltetrahydrofolate cyclohydrolase [Budvicia aquatica].	46.90	290	144	3	1	290	1	280	7e-81	258
rs:WP_036085404	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria booriae].	49.83	289	134	4	3	291	2	279	7e-81	258
rs:XP_007223192	hypothetical protein PRUPE_ppa009263mg [Prunus persica].	45.39	293	154	2	3	293	9	297	7e-81	258
rs:WP_019378272	5,10-methylene-tetrahydrofolate dehydrogenase [Virgibacillus halodenitrificans].	48.62	290	138	3	1	290	1	279	7e-81	258
rs:XP_009621986	PREDICTED: bifunctional protein FolD 2 isoform X2 [Nicotiana tomentosiformis].	46.42	293	151	2	3	293	9	297	7e-81	259
tr:A0A061R604_9CHLO	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:JAC65966.1};	46.05	291	151	2	5	293	20	306	7e-81	259
rs:WP_031871874	bifunctional protein FolD [Staphylococcus aureus].	45.86	290	146	3	1	290	1	279	7e-81	258
rs:WP_002471878	tetrahydrofolate dehydrogenase [Staphylococcus pettenkoferi].	46.90	290	143	3	1	290	1	279	7e-81	258
rs:WP_038960942	hypothetical protein [Atribacteria bacterium SCGC AB-164-A22].	46.08	293	151	1	1	293	1	286	7e-81	258
rs:WP_019336183	tetrahydrofolate dehydrogenase [Lactococcus garvieae].	47.93	290	140	4	4	293	2	280	7e-81	258
rs:WP_013221002	methenyltetrahydrofolate cyclohydrolase [Nitrosococcus watsonii].	47.42	291	143	3	1	291	1	281	7e-81	258
tr:G2ZLR7_9RALS	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.90	286	138	3	1	286	1	275	8e-81	258
rs:WP_028544150	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus taiwanensis].	46.74	291	144	3	1	291	1	280	8e-81	258
rs:WP_000225833	bifunctional protein FolD [Staphylococcus aureus].	45.86	290	146	3	1	290	1	279	8e-81	258
sp:MTD2L_CALJA	RecName: Full=Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2; AltName: Full=NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein; Short=MTHFD2-like; Includes: RecName: Full=NAD-dependent methylenetetrahydrofolate dehydrogenase; EC=1.5.1.15; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9;	48.32	298	147	3	3	294	51	347	8e-81	260
rs:WP_026988401	methenyltetrahydrofolate cyclohydrolase [Fodinicurvata fenggangensis].	47.59	290	146	2	3	292	4	287	8e-81	258
rs:WP_028504573	5,10-methylene-tetrahydrofolate cyclohydrolase [Ruminococcus sp. FC2018].	50.17	289	133	4	3	291	2	279	8e-81	258
rs:WP_023923339	FolD protein [Ruminococcus lactaris].	47.54	284	138	3	3	286	2	274	8e-81	258
rs:WP_018401397	hypothetical protein [gamma proteobacterium SCGC AB-629-P17].	49.48	289	132	3	5	293	3	277	8e-81	258
rs:WP_006054187	5,10-methylene-tetrahydrofolate dehydrogenase [Halogeometricum borinquense].	47.55	286	148	2	4	289	3	286	8e-81	258
rs:WP_022270416	bifunctional protein FolD [Eubacterium siraeum CAG:80].	49.30	286	131	3	5	290	3	274	8e-81	258
rs:WP_013956386	5,10-methylene-tetrahydrofolate dehydrogenase [Cupriavidus necator].	46.23	292	146	3	1	292	1	281	8e-81	258
rs:WP_046741228	methenyltetrahydrofolate cyclohydrolase [Lampropedia sp. CT6].	48.14	295	139	5	1	293	1	283	8e-81	258
rs:WP_035167252	methenyltetrahydrofolate cyclohydrolase [Lactobacillus curieae].	49.31	288	130	5	3	286	2	277	8e-81	258
rs:WP_013939606	5,10-methylene-tetrahydrofolate dehydrogenase [Myxococcus fulvus].	48.82	297	140	4	1	296	1	286	8e-81	258
rs:WP_028224404	methenyltetrahydrofolate cyclohydrolase [Burkholderia ferrariae].	49.30	286	134	3	1	286	1	275	8e-81	258
rs:WP_039388886	methenyltetrahydrofolate cyclohydrolase [Novosphingobium sp. MBES04].	47.95	292	147	2	1	292	1	287	8e-81	258
rs:WP_013628587	5,10-methylene-tetrahydrofolate dehydrogenase [Planctomyces brasiliensis].	47.24	290	144	2	1	290	1	281	8e-81	258
rs:WP_034371735	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter sp. MIT 05-5293].	47.04	287	141	4	5	291	3	278	8e-81	258
rs:WP_019414108	hypothetical protein [Paenisporosarcina sp. TG20].	45.73	293	148	4	1	293	1	282	8e-81	258
rs:WP_022477541	bifunctional protein FolD [Coraliomargarita sp. CAG:312].	46.90	290	150	2	4	293	2	287	9e-81	258
rs:XP_009965861	PREDICTED: LOW QUALITY PROTEIN: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Tyto alba].	49.19	307	138	5	3	294	30	333	9e-81	259
rs:WP_023950067	5,10-methylene-tetrahydrofolate dehydrogenase [Pelistega sp. HM-7].	46.08	293	147	3	1	293	1	282	9e-81	258
rs:WP_035990592	methenyltetrahydrofolate cyclohydrolase [Burkholderia caribensis].	48.97	292	138	4	1	292	1	281	9e-81	258
rs:WP_028253579	methenyltetrahydrofolate cyclohydrolase [Variovorax sp. URHB0020].	48.29	292	140	3	1	292	1	281	9e-81	258
rs:WP_031897920	bifunctional protein FolD [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	9e-81	258
rs:WP_035649063	hypothetical protein [Lachnospiraceae bacterium AD3010].	51.93	285	128	4	4	288	6	281	9e-81	258
rs:WP_002452926	tetrahydrofolate dehydrogenase [Staphylococcus capitis].	45.52	290	147	3	1	290	1	279	9e-81	258
rs:WP_023504644	methenyltetrahydrofolate cyclohydrolase/dehydrogenase [uncultured archaeon A07HR60].	45.73	293	156	3	6	297	5	295	9e-81	258
rs:WP_021919656	bifunctional protein FolD [Firmicutes bacterium CAG:114].	48.79	289	134	3	3	291	2	276	9e-81	257
rs:XP_011990921	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X4 [Ovis aries musimon].	49.48	291	139	4	11	294	1	290	9e-81	258
rs:WP_005612227	5,10-methylene-tetrahydrofolate dehydrogenase [Ruminococcus lactaris].	47.89	284	137	3	3	286	2	274	1e-80	257
rs:WP_000225835	tetrahydrofolate dehydrogenase [Staphylococcus aureus].	45.86	290	146	3	1	290	1	279	1e-80	258
rs:WP_009117124	methenyltetrahydrofolate cyclohydrolase [Neisseria wadsworthii].	48.97	290	138	2	1	290	1	280	1e-80	258
rs:WP_025151667	methenyltetrahydrofolate cyclohydrolase [Morganella morganii].	47.77	291	142	3	1	291	1	281	1e-80	258
rs:WP_005841568	5,10-methylene-tetrahydrofolate dehydrogenase [Mitsuokella multacida].	47.12	295	144	3	1	293	1	285	1e-80	258
rs:WP_006269746	tetrahydrofolate dehydrogenase [Streptococcus constellatus].	47.93	290	141	2	4	293	3	282	1e-80	258
tr:G1NTQ8_MYOLU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMLUP00000000566}; Flags: Fragment;	48.01	302	144	5	3	295	4	301	1e-80	259
rs:WP_035824532	methenyltetrahydrofolate cyclohydrolase [Cupriavidus sp. SK-4].	46.23	292	146	3	1	292	1	281	1e-80	258
sp:FOLD2_HALMA	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.02	285	149	2	5	289	4	286	1e-80	258
rs:WP_022142590	bifunctional protein FolD [Clostridium sp. CAG:230].	49.83	289	134	4	4	292	3	280	1e-80	257
rs:WP_028533130	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus].	48.11	291	140	4	1	291	1	280	1e-80	258
rs:WP_005761829	methenyltetrahydrofolate cyclohydrolase [Pasteurella bettyae].	48.31	296	143	2	1	296	1	286	1e-80	258
rs:WP_006693015	5,10-methylene-tetrahydrofolate dehydrogenase [Selenomonas infelix].	48.97	290	135	4	3	290	2	280	1e-80	258
tr:C9MYI9_9FUSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.21	290	144	3	5	293	17	295	1e-80	258
rs:XP_008111362	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Anolis carolinensis].	49.83	295	141	4	3	291	83	376	1e-80	261
rs:WP_034986793	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus sucicola].	46.76	293	145	3	1	293	1	282	1e-80	258
rs:WP_002269464	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus mutans].	49.66	290	136	2	4	293	3	282	1e-80	257
rs:WP_044355944	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. E194].	48.11	291	140	4	1	291	1	280	1e-80	258
rs:WP_018914440	hypothetical protein [Thiomonas sp. FB-6].	47.60	292	141	4	1	291	1	281	1e-80	257
rs:WP_042322736	methenyltetrahydrofolate cyclohydrolase [Burkholderia ginsengisoli].	49.14	291	137	3	1	291	1	280	1e-80	257
rs:XP_005555125	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X5 [Macaca fascicularis].	48.28	290	143	3	11	294	1	289	1e-80	258
rs:WP_020736401	5,10-methylene-tetrahydrofolate dehydrogenase [Sorangium cellulosum].	44.90	294	151	3	1	293	1	284	1e-80	258
rs:XP_008350085	PREDICTED: bifunctional protein FolD 2-like [Malus domestica].	46.08	293	152	2	3	293	9	297	1e-80	258
rs:WP_018310342	5,10-methylene-tetrahydrofolate dehydrogenase [Cupriavidus sp. UYPR2.512].	46.23	292	146	3	1	292	1	281	1e-80	257
rs:WP_035821601	5,10-methylene-tetrahydrofolate cyclohydrolase [Janthinobacterium sp. RA13].	47.42	291	142	4	1	291	1	280	1e-80	257
rs:WP_002264705	tetrahydrofolate dehydrogenase [Streptococcus mutans].	49.66	290	136	2	4	293	3	282	1e-80	257
rs:WP_027007229	hypothetical protein [Conexibacter woesei].	47.59	290	141	2	1	290	1	279	1e-80	258
rs:WP_010408395	5,10-methylene-tetrahydrofolate dehydrogenase [Citromicrobium sp. JLT1363].	49.83	289	141	1	1	289	1	285	1e-80	258
tr:A0A098F0W5_9BACI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.08	291	142	4	1	291	1	279	1e-80	257
rs:WP_007848532	5,10-methylene-tetrahydrofolate dehydrogenase [Acidovorax sp. CF316].	47.20	286	140	3	1	286	1	275	1e-80	257
sp:FOLD_FRATF	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.57	288	139	3	5	291	3	279	1e-80	257
rs:XP_012366086	PREDICTED: LOW QUALITY PROTEIN: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Nomascus leucogenys].	47.96	294	146	3	3	290	37	329	1e-80	259
gp:CP010941_964	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus]	45.86	290	146	3	1	290	1	279	1e-80	257
rs:WP_046288792	methenyltetrahydrofolate cyclohydrolase [Blochmannia endosymbiont of Polyrhachis (Hedomyrma) turneri].	45.49	288	147	2	1	288	1	278	1e-80	257
tr:I3K9W5_ORENI	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSONIP00000017910}; Flags: Fragment;	47.02	302	153	3	2	297	25	325	1e-80	259
sp:FOLD_NOSP7	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.94	294	146	3	2	291	5	292	1e-80	258
tr:X5EMM2_NEIME	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	53.17	252	108	2	38	289	1	242	1e-80	256
tr:S9U960_9TRYP	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:EPY25319.1};	44.11	297	158	4	1	293	1	293	1e-80	258
rs:WP_021006947	bifunctional protein FolD [Variovorax paradoxus].	48.29	292	140	3	1	292	1	281	1e-80	257
rs:WP_024403951	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	48.61	288	138	2	5	292	3	280	1e-80	257
rs:XP_006339252	PREDICTED: bifunctional protein FolD 2-like [Solanum tuberosum].	46.42	293	151	2	3	293	9	297	1e-80	258
rs:XP_001980871	GG17397 [Drosophila erecta].	46.13	297	153	3	3	293	2	297	1e-80	258
rs:WP_010738206	MULTISPECIES: tetrahydrofolate dehydrogenase [Enterococcus].	48.96	288	136	4	3	290	2	278	1e-80	257
rs:WP_035238385	methenyltetrahydrofolate cyclohydrolase [Desulfobacter vibrioformis].	48.31	296	149	3	1	293	1	295	1e-80	258
rs:WP_013595162	5,10-methylene-tetrahydrofolate dehydrogenase [Acidovorax avenae].	47.26	292	143	4	1	292	1	281	1e-80	257
tr:A0A024RDE0_HUMAN	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like, isoform CRA_a {ECO:0000313|EMBL:EAX05706.1};	48.97	290	141	3	11	294	1	289	1e-80	257
rs:WP_022355637	bifunctional protein FolD [Firmicutes bacterium CAG:308].	48.07	285	133	5	5	286	2	274	1e-80	257
rs:WP_002307728	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus mutans].	49.66	290	136	2	4	293	3	282	1e-80	257
rs:WP_015910348	5,10-methylene-tetrahydrofolate dehydrogenase [Halorubrum lacusprofundi].	50.00	286	139	4	5	289	14	296	1e-80	258
rs:WP_009373148	5,10-methylene-tetrahydrofolate dehydrogenase [alpha proteobacterium HIMB114].	48.43	287	139	4	5	291	2	279	1e-80	257
tr:U6B7D2_9BACL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.88	288	141	3	3	290	2	277	1e-80	257
rs:WP_031559210	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactococcus lactis].	48.10	289	139	3	5	293	3	280	1e-80	257
tr:A0A0B2R2C7_GLYSO	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KHN28206.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KHN28206.1}; EC=3.5.4.9 {ECO:0000313|EMBL:KHN28206.1};	45.39	293	154	2	3	293	2	290	1e-80	258
rs:WP_015555388	methylenetetrahydrofolate dehydrogenase [Taylorella equigenitalis].	48.26	288	138	3	4	291	3	279	1e-80	257
rs:WP_042422709	methenyltetrahydrofolate cyclohydrolase [Comamonas granuli].	46.92	292	144	3	1	292	1	281	1e-80	257
rs:WP_041787370	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus intermedius].	48.28	290	140	2	4	293	3	282	1e-80	257
rs:XP_006298219	hypothetical protein CARUB_v10014277mg [Capsella rubella].	45.21	292	154	2	2	291	8	295	1e-80	258
rs:WP_035947692	methenyltetrahydrofolate cyclohydrolase, partial [Burkholderia multivorans].	49.12	285	134	3	1	285	1	274	1e-80	257
rs:WP_046298380	methenyltetrahydrofolate cyclohydrolase [Verrucomicrobia bacterium IMCC26134].	49.31	288	142	2	4	290	2	286	1e-80	257
rs:XP_011530281	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Homo sapiens].	48.99	298	145	3	3	294	154	450	1e-80	262
rs:XP_002882773	hypothetical protein ARALYDRAFT_478591 [Arabidopsis lyrata subsp. lyrata].	44.52	292	156	2	2	291	8	295	2e-80	258
rs:WP_020616784	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus daejeonensis].	47.77	291	141	4	1	291	1	280	2e-80	257
rs:WP_028769558	methenyltetrahydrofolate cyclohydrolase [Silanimonas lenta].	48.15	297	142	3	1	295	1	287	2e-80	258
tr:T1ZE91_STRIT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.28	290	140	2	4	293	5	284	2e-80	257
rs:WP_040852430	methenyltetrahydrofolate cyclohydrolase [Nitrosospira sp. APG3].	47.65	298	133	4	1	292	1	281	2e-80	257
rs:WP_002465409	tetrahydrofolate dehydrogenase [Staphylococcus warneri].	46.55	290	144	3	1	290	1	279	2e-80	257
rs:WP_029716877	hypothetical protein [Atribacteria bacterium SCGC AAA255-G05].	45.73	293	152	1	1	293	1	286	2e-80	257
rs:WP_031587840	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium P6A3].	50.00	284	131	3	3	286	2	274	2e-80	257
rs:WP_035488310	methenyltetrahydrofolate cyclohydrolase [Burkholderia multivorans].	48.45	291	139	3	1	291	1	280	2e-80	257
rs:XP_008235028	PREDICTED: bifunctional protein FolD 2-like isoform X1 [Prunus mume].	45.73	293	153	2	3	293	9	297	2e-80	258
rs:WP_008977743	5,10-methylene-tetrahydrofolate dehydrogenase [Erysipelotrichaceae bacterium 5_2_54FAA].	47.37	285	139	3	3	286	2	276	2e-80	257
rs:WP_016294088	FolD protein [Lachnospiraceae bacterium M18-1].	48.24	284	136	4	3	286	2	274	2e-80	257
rs:WP_029461399	methenyltetrahydrofolate cyclohydrolase [Comamonadaceae bacterium H1].	47.20	286	140	3	1	286	1	275	2e-80	257
tr:T2MGF6_HYDVU	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase,mitochondrial {ECO:0000313|EMBL:CDG71358.1}; Flags: Fragment;	47.24	290	142	4	2	291	6	284	2e-80	257
rs:WP_008169826	methenyltetrahydrofolate cyclohydrolase [Marinobacter manganoxydans].	48.44	289	139	2	2	290	3	281	2e-80	257
tr:G5AXG4_HETGA	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:EHB01725.1};	48.14	295	118	3	3	295	39	300	2e-80	258
rs:WP_015013996	5,10-methylene-tetrahydrofolate dehydrogenase [Acidovorax sp. KKS102].	46.92	292	144	3	1	292	1	281	2e-80	257
rs:WP_040964668	methenyltetrahydrofolate cyclohydrolase [Erythrobacter vulgaris].	48.29	292	147	1	1	292	1	288	2e-80	257
sp:FOLD_EXISA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.79	289	135	4	3	291	2	277	2e-80	256
tr:A0A096P9X9_OSTTA	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase,conserved site {ECO:0000313|EMBL:CEG01746.1};	45.58	294	154	2	2	293	7	296	2e-80	257
sp:FOLD_DESVM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.95	286	139	2	5	290	3	281	2e-80	257
rs:WP_041823123	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus intermedius].	48.28	290	140	2	4	293	3	282	2e-80	257
rs:WP_007637704	methylenetetrahydrofolate dehydrogenase [Paraglaciecola psychrophila].	47.77	291	142	2	1	291	1	281	2e-80	257
rs:WP_010719794	FolD protein [Enterococcus hirae].	48.96	288	136	4	3	290	2	278	2e-80	257
rs:WP_020201173	5,10-methylene-tetrahydrofolate dehydrogenase [Cupriavidus sp. WS].	45.55	292	148	3	1	292	1	281	2e-80	257
tr:L5MK30_MYODS	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:ELK38736.1};	49.83	295	141	3	3	291	75	368	2e-80	260
gp:CP003858_349	methenyltetrahydrofolate cyclohydrolase [Streptococcus intermedius C270]	48.28	290	140	2	4	293	5	284	2e-80	257
rs:WP_002925550	tetrahydrofolate dehydrogenase [Streptococcus sanguinis].	47.08	291	144	3	3	293	2	282	2e-80	257
rs:WP_034188953	methenyltetrahydrofolate cyclohydrolase [Burkholderia cenocepacia].	48.45	291	139	3	1	291	1	280	2e-80	257
rs:WP_035985453	5,10-methylene-tetrahydrofolate cyclohydrolase [Leptolyngbya sp. KIOST-1].	46.02	289	150	2	5	293	4	286	2e-80	257
rs:WP_002281690	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus mutans].	49.66	290	136	2	4	293	3	282	2e-80	257
tr:G7MT30_MACMU	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EHH25926.1};	48.62	290	142	3	11	294	1	289	2e-80	257
rs:WP_027096049	5,10-methylene-tetrahydrofolate cyclohydrolase [[Clostridium] viride].	47.10	293	141	4	1	293	1	279	2e-80	256
rs:WP_013193567	5,10-methylene-tetrahydrofolate dehydrogenase [Methanohalobium evestigatum].	47.24	290	142	2	4	293	10	288	2e-80	257
rs:WP_006286552	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus popilliae].	46.05	291	146	4	1	291	1	280	2e-80	257
rs:WP_024396909	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	48.61	288	138	2	5	292	3	280	2e-80	257
rs:XP_002096896	GE24801 [Drosophila yakuba].	46.13	297	153	3	3	293	2	297	2e-80	257
rs:XP_010671911	PREDICTED: bifunctional protein FolD 4, chloroplastic-like [Beta vulgaris subsp. vulgaris].	47.08	291	148	2	3	291	73	359	2e-80	259
rs:WP_026833560	5,10-methylene-tetrahydrofolate cyclohydrolase [Exiguobacterium undae].	46.55	290	143	3	1	290	1	278	2e-80	256
rs:WP_005555574	5,10-methylene-tetrahydrofolate dehydrogenase [Natronococcus amylolyticus].	46.67	285	150	2	4	288	3	285	2e-80	257
tr:S9TR55_PAEAL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.11	291	140	4	1	291	2	281	2e-80	257
tr:J4JM20_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.33	263	117	3	29	291	15	266	2e-80	256
rs:WP_029715208	MULTISPECIES: hypothetical protein [unclassified Atribacteria].	46.05	291	150	1	1	291	1	284	2e-80	257
gpu:CP009517_1469	Methylenetetrahydrofolate dehydrogenase (NADP+) [Methanosarcina barkeri 3]	46.23	292	146	2	2	293	7	287	2e-80	257
rs:WP_026308148	hypothetical protein, partial [Atribacteria bacterium SCGC AAA252-M02].	45.73	293	152	1	1	293	1	286	2e-80	257
rs:WP_023163929	tetrahydrofolate dehydrogenase [Lactococcus lactis].	48.10	289	139	3	5	293	3	280	2e-80	257
rs:WP_017327422	hypothetical protein [Synechococcus sp. PCC 7336].	48.77	285	140	3	2	286	4	282	2e-80	257
sp:FOLD_EXIS2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.22	288	140	3	3	290	2	277	2e-80	256
tr:K1YT09_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.46	295	153	1	1	293	1	295	2e-80	257
rs:WP_007080973	methenyltetrahydrofolate cyclohydrolase [Rhodanobacter fulvus].	47.93	290	141	2	1	290	1	280	2e-80	257
rs:WP_015589066	bifunctional protein FolD [Wolbachia endosymbiont of Drosophila simulans].	48.95	286	138	4	5	289	4	282	2e-80	257
rs:WP_019370765	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas sp. ATCC 31555].	46.92	292	144	2	1	292	1	281	2e-80	257
rs:XP_010788831	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Notothenia coriiceps].	48.16	299	148	3	2	294	50	347	2e-80	259
rs:WP_035403337	hypothetical protein [Faecalitalea cylindroides].	48.07	285	133	5	5	286	2	274	2e-80	257
rs:XP_004249325	PREDICTED: bifunctional protein FolD 2 [Solanum lycopersicum].	46.08	293	152	2	3	293	9	297	2e-80	257
rs:WP_006268293	tetrahydrofolate dehydrogenase [Streptococcus constellatus].	47.59	290	142	2	4	293	3	282	2e-80	256
rs:WP_046413975	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacteroides sp. UNK.MGS-13].	47.74	266	137	1	4	269	2	265	2e-80	256
rs:WP_034786559	5,10-methylene-tetrahydrofolate cyclohydrolase [Janthinobacterium lividum].	47.42	291	142	3	1	291	1	280	2e-80	256
rs:WP_016225274	hypothetical protein [Lachnospiraceae bacterium 3-2].	46.71	289	143	3	3	291	2	279	2e-80	256
rs:WP_016426972	FolD protein [Paenisporosarcina sp. HGH0030].	45.39	293	149	4	1	293	1	282	2e-80	256
rs:XP_008808628	PREDICTED: bifunctional protein FolD 4, chloroplastic-like isoform X2 [Phoenix dactylifera].	47.95	292	146	2	2	291	150	437	2e-80	262
rs:WP_015692938	5,10-methylene-tetrahydrofolate dehydrogenase [Saprospira grandis].	43.55	287	162	0	4	290	2	288	2e-80	257
tr:A0A090SWE1_9VIBR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.20	251	115	2	41	291	1	241	2e-80	255
rs:WP_034452415	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. AE2032].	48.80	291	136	4	1	289	1	280	2e-80	256
rs:WP_015876431	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia glumae].	48.95	286	135	4	1	286	1	275	2e-80	256
rs:XP_003625904	Bifunctional protein folD [Medicago truncatula].	46.08	293	152	2	3	293	2	290	2e-80	257
rs:WP_035972093	methenyltetrahydrofolate cyclohydrolase [Burkholderia dolosa].	48.45	291	139	4	1	291	1	280	2e-80	256
tr:G3QIK0_GORGO	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000002211};	48.28	290	142	4	3	286	37	324	2e-80	259
rs:WP_031760544	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	2e-80	256
tr:M3YCK8_MUSPF	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMPUP00000009065};	48.97	290	141	3	11	294	1	289	2e-80	257
tr:K5AAL9_PAEAL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.45	291	139	4	1	291	2	281	2e-80	256
rs:WP_029341095	5,10-methylene-tetrahydrofolate cyclohydrolase [Exiguobacterium acetylicum].	46.55	290	143	3	1	290	1	278	3e-80	256
rs:WP_027016083	methenyltetrahydrofolate cyclohydrolase [Comamonas composti].	48.81	295	135	6	1	292	1	282	3e-80	256
tr:A0A023GIC0_9ACAR	SubName: Full=Putative methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:JAC33702.1};	46.08	293	155	2	3	293	32	323	3e-80	258
rs:WP_025803737	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter sp. CIT045].	49.48	289	135	4	5	293	3	280	3e-80	256
rs:WP_010650816	5,10-methylene-tetrahydrofolate dehydrogenase [Oceanobacillus massiliensis].	48.62	290	138	3	1	290	1	279	3e-80	256
sp:FOLD_SYNY3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.21	292	154	2	2	293	7	292	3e-80	257
rs:WP_000225838	tetrahydrofolate dehydrogenase [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	3e-80	256
rs:WP_045531367	methenyltetrahydrofolate cyclohydrolase [Comamonadaceae bacterium A1].	45.89	292	147	3	1	292	1	281	3e-80	256
sp:FOLD_WOLWR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.60	286	136	3	5	289	4	279	3e-80	256
rs:WP_045099440	methenyltetrahydrofolate cyclohydrolase [Tatlockia micdadei].	44.37	293	153	2	1	293	1	283	3e-80	256
rs:WP_015139950	5,10-methylene-tetrahydrofolate dehydrogenase [Nostoc sp. PCC 7524].	46.39	291	150	2	2	292	5	289	3e-80	257
rs:WP_017877031	hypothetical protein [Janthinobacterium sp. CG3].	47.08	291	143	3	1	291	1	280	3e-80	256
gp:CP003800_1332	methenyltetrahydrofolate cyclohydrolase [Streptococcus constellatus subsp. pharyngis C232]	47.59	290	142	2	4	293	5	284	3e-80	256
rs:WP_002435335	MULTISPECIES: tetrahydrofolate dehydrogenase [Staphylococcus].	45.17	290	148	3	1	290	1	279	3e-80	256
rs:WP_020588829	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfobacter curvatus].	47.46	295	153	1	1	293	1	295	3e-80	257
rs:WP_010751502	FolD protein [Enterococcus villorum].	47.92	288	139	4	3	290	2	278	3e-80	256
rs:WP_038499325	methenyltetrahydrofolate cyclohydrolase [Basilea psittacipulmonis].	46.76	293	145	4	1	293	1	282	3e-80	256
rs:WP_037598708	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus sp. AS20].	47.59	290	142	2	4	293	3	282	3e-80	256
rs:XP_012252890	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Athalia rosae].	48.81	295	143	3	2	290	27	319	3e-80	258
tr:M4A745_XIPMA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSXMAP00000010289};	46.98	298	151	3	2	293	20	316	3e-80	258
tr:A0A077VJ44_STAAU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.86	290	146	3	1	290	1	279	3e-80	256
rs:XP_003772901	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Sarcophilus harrisii].	48.48	297	146	3	3	293	34	329	3e-80	259
rs:WP_034574000	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter sanguini].	47.55	286	139	4	5	290	3	277	3e-80	256
rs:XP_008570690	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Galeopterus variegatus].	48.28	290	143	3	11	294	1	289	3e-80	256
rs:WP_017724115	tetrahydrofolate dehydrogenase [Staphylococcus xylosus].	45.86	290	146	3	1	290	1	279	3e-80	256
rs:WP_038703750	5,10-methylene-tetrahydrofolate cyclohydrolase [Planococcus sp. PAMC 21323].	47.10	293	144	4	1	293	1	282	3e-80	256
rs:WP_034961451	methenyltetrahydrofolate cyclohydrolase [Erythrobacter longus].	48.29	292	147	1	1	292	1	288	3e-80	257
rs:XP_012082722	PREDICTED: bifunctional protein FolD 2 [Jatropha curcas].	45.36	291	153	2	3	291	9	295	3e-80	257
rs:WP_043044594	bifunctional protein FolD [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	3e-80	256
rs:WP_002911972	tetrahydrofolate dehydrogenase [Streptococcus sanguinis].	46.74	291	145	3	3	293	2	282	3e-80	256
rs:WP_003705927	tetrahydrofolate dehydrogenase [Lactobacillus salivarius].	48.12	293	141	3	1	293	1	282	3e-80	256
tr:A0A077UAS1_STAAU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.86	290	146	3	1	290	1	279	3e-80	256
rs:WP_013535081	methenyltetrahydrofolate cyclohydrolase [Pseudoxanthomonas suwonensis].	50.00	288	132	3	1	286	1	278	3e-80	256
rs:WP_024752877	hypothetical protein [Treponema phagedenis].	46.37	289	151	3	1	289	1	285	3e-80	256
tr:A0A078HWF2_BRANA	SubName: Full=BnaC05g40770D protein {ECO:0000313|EMBL:CDY42142.1};	45.24	294	155	2	2	293	7	296	3e-80	256
tr:G3NLJ7_GASAC	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGACP00000006210}; Flags: Fragment;	47.70	304	146	4	2	293	35	337	3e-80	258
rs:WP_046207899	methenyltetrahydrofolate cyclohydrolase [Staphylococcus cohnii].	46.21	290	145	3	1	290	1	279	3e-80	256
rs:XP_007200503	hypothetical protein PRUPE_ppa009269mg [Prunus persica].	45.39	293	154	2	3	293	9	297	3e-80	256
rs:WP_002266428	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus mutans].	49.66	290	136	2	4	293	3	282	3e-80	256
rs:WP_008002893	5,10-methylene-tetrahydrofolate dehydrogenase [Halorubrum lipolyticum].	49.48	289	142	4	2	289	12	297	4e-80	257
rs:WP_032603944	methenyltetrahydrofolate cyclohydrolase [Staphylococcus epidermidis].	46.21	290	145	3	1	290	1	279	4e-80	256
rs:WP_039677317	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus constellatus].	47.59	290	142	2	4	293	3	282	4e-80	256
rs:WP_036373927	5,10-methylene-tetrahydrofolate cyclohydrolase [Mitsuokella jalaludinii].	47.12	295	144	3	1	293	1	285	4e-80	256
tr:A2W8Z6_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.45	291	139	4	1	291	23	302	4e-80	257
rs:WP_029092246	hypothetical protein [Brochothrix thermosphacta].	46.21	290	146	3	3	292	2	281	4e-80	256
rs:WP_024392451	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	48.26	288	139	2	5	292	3	280	4e-80	256
rs:XP_004926753	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Bombyx mori].	47.12	295	147	5	3	290	2	294	4e-80	256
rs:XP_008808627	PREDICTED: bifunctional protein FolD 4, chloroplastic-like isoform X1 [Phoenix dactylifera].	47.95	292	146	2	2	291	150	437	4e-80	261
sp:FOLD_VARPS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.29	292	140	3	1	292	1	281	4e-80	256
rs:WP_008818231	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Firmicutes].	47.40	289	138	4	5	291	4	280	4e-80	256
sp:FOLD_NITEC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.52	290	139	4	1	286	1	275	4e-80	256
rs:WP_010303158	5,10-methylene-tetrahydrofolate dehydrogenase [Kurthia sp. JC8E].	47.44	293	143	4	1	293	1	282	4e-80	256
rs:WP_020683046	hypothetical protein [Marinobacterium rhizophilum].	47.40	289	146	2	2	290	12	294	4e-80	256
rs:XP_010592442	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Loxodonta africana].	48.28	290	143	3	11	294	1	289	4e-80	256
rs:XP_004518006	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X3 [Ceratitis capitata].	47.96	294	146	3	3	290	9	301	4e-80	257
rs:WP_002921925	bifunctional protein FolD [Streptococcus sanguinis].	46.74	291	145	3	3	293	2	282	4e-80	256
rs:WP_002910307	tetrahydrofolate dehydrogenase [Streptococcus sanguinis].	46.74	291	145	3	3	293	2	282	4e-80	256
tr:U1QE61_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.39	293	157	3	6	297	5	295	4e-80	256
rs:WP_018417511	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia sp. WSM4176].	48.63	292	139	3	1	292	1	281	4e-80	256
rs:WP_042223493	5,10-methylene-tetrahydrofolate cyclohydrolase [Oceanobacillus manasiensis].	46.39	291	143	5	1	290	1	279	4e-80	256
rs:WP_008000238	5,10-methylene-tetrahydrofolate dehydrogenase [Halorubrum aidingense].	50.35	286	138	4	5	289	16	298	4e-80	257
sp:FOLD_STAA3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.52	290	147	3	1	290	1	279	4e-80	256
rs:WP_022174716	bifunctional protein FolD [Clostridium sp. CAG:557].	47.74	287	138	4	4	289	3	278	4e-80	256
rs:WP_033170163	5,10-methylene-tetrahydrofolate cyclohydrolase [Selenomonas sp. ND2010].	47.80	295	142	3	1	293	1	285	4e-80	256
rs:WP_009063827	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Clostridium].	47.75	289	141	3	3	291	2	280	4e-80	256
rs:WP_046180424	5,10-methylene-tetrahydrofolate cyclohydrolase [Domibacillus sp. PAMC 80007].	47.59	290	141	3	1	290	1	279	4e-80	256
rs:WP_002919438	bifunctional protein FolD [Streptococcus sanguinis].	46.74	291	145	3	3	293	2	282	4e-80	256
rs:WP_027104757	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium V9D3004].	50.35	288	131	4	3	290	2	277	4e-80	256
rs:WP_023409274	5,10-methylene-tetrahydrofolate dehydrogenase [uncultured Desulfofustis sp. PB-SRB1].	46.80	297	152	3	1	293	1	295	4e-80	256
sp:FOLD_BURCC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.45	291	139	3	1	291	1	280	4e-80	256
rs:WP_002904060	tetrahydrofolate dehydrogenase [Streptococcus sanguinis].	46.74	291	145	3	3	293	2	282	4e-80	256
sp:FOLD_STRSV	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.08	291	144	3	3	293	2	282	4e-80	256
tr:A0A077USW1_STAAU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.52	290	147	3	1	290	1	279	4e-80	256
rs:WP_037356192	5,10-methylene-tetrahydrofolate cyclohydrolase [Selenomonas sp. FC4001].	47.26	292	142	3	1	290	1	282	4e-80	256
rs:XP_009942397	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Opisthocomus hoazin].	46.80	297	151	3	3	295	10	303	4e-80	257
rs:WP_014865183	5,10-methylene-tetrahydrofolate dehydrogenase [Natrinema sp. J7-2].	45.80	286	153	2	4	289	3	286	4e-80	256
rs:WP_035067192	methenyltetrahydrofolate cyclohydrolase [Desulfovibrio termitidis].	48.60	286	140	2	5	290	3	281	4e-80	256
tr:A0A0D6DKR6_STAAU	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:BAR11226.1};	45.52	290	147	3	1	290	9	287	4e-80	256
rs:WP_022517304	bifunctional protein FolD [Roseburia sp. CAG:100].	49.12	283	133	3	4	286	3	274	4e-80	256
rs:WP_026432588	methenyltetrahydrofolate cyclohydrolase [Acidovorax oryzae].	47.26	292	143	4	1	292	1	281	4e-80	256
rs:WP_024534544	5,10-methylene-tetrahydrofolate cyclohydrolase [Sporosarcina sp. EUR3 2.2.2].	45.73	293	148	4	1	293	1	282	4e-80	256
rs:WP_042418503	methenyltetrahydrofolate cyclohydrolase [Comamonas aquatica].	49.83	289	129	5	1	286	1	276	5e-80	256
rs:WP_039715738	5,10-methylene-tetrahydrofolate cyclohydrolase [Scytonema millei].	44.52	292	156	2	2	293	5	290	5e-80	256
rs:WP_002284938	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus mutans].	49.31	290	137	2	4	293	3	282	5e-80	256
rs:WP_008691194	5,10-methylene-tetrahydrofolate dehydrogenase [Eubacterium sp. 3_1_31].	47.37	285	139	3	3	286	2	276	5e-80	256
rs:WP_038249913	methenyltetrahydrofolate cyclohydrolase [Wolbachia endosymbiont of Glossina morsitans morsitans].	48.60	286	136	3	5	289	4	279	5e-80	256
rs:WP_040223360	methenyltetrahydrofolate cyclohydrolase, partial [Klebsiella pneumoniae].	51.30	269	121	3	1	269	1	259	5e-80	255
gpu:CP009524_977	Methylenetetrahydrofolate dehydrogenase (NADP+) [Methanosarcina sp. Kolksee]	45.89	292	147	2	2	293	7	287	5e-80	256
rs:WP_040106901	methenyltetrahydrofolate cyclohydrolase [Salinicoccus roseus].	47.93	290	138	5	1	290	1	277	5e-80	256
rs:XP_010427252	PREDICTED: bifunctional protein FolD 4, chloroplastic-like [Camelina sativa].	45.89	292	152	2	2	291	54	341	5e-80	258
rs:WP_013831669	5,10-methylene-tetrahydrofolate dehydrogenase [Novosphingobium sp. PP1Y].	49.83	291	139	3	3	292	4	288	5e-80	256
tr:C6TL94_SOYBN	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:ACU23686.1};	45.05	293	155	2	3	293	2	290	5e-80	256
rs:WP_034747393	5,10-methylene-tetrahydrofolate cyclohydrolase [Janthinobacterium lividum].	47.08	291	143	4	1	291	1	280	5e-80	256
tr:B9BZ17_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.45	291	139	3	1	291	51	330	5e-80	257
tr:F7QW09_9LACO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.12	293	141	3	1	293	8	289	5e-80	256
rs:WP_002606948	hypothetical protein [[Clostridium] innocuum].	47.40	289	138	4	5	291	4	280	5e-80	256
rs:XP_004952097	PREDICTED: bifunctional protein FolD 4, chloroplastic [Setaria italica].	47.95	292	146	2	2	291	77	364	5e-80	258
rs:XP_009412975	PREDICTED: bifunctional protein FolD 4, chloroplastic-like [Musa acuminata subsp. malaccensis].	47.08	291	148	2	3	291	71	357	5e-80	258
rs:WP_002483707	bifunctional protein FolD [Staphylococcus saprophyticus].	45.86	290	146	3	1	290	1	279	5e-80	256
rs:XP_004518005	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Ceratitis capitata].	47.96	294	146	3	3	290	10	302	5e-80	257
rs:WP_004187841	bifunctional protein FolD [Streptococcus sanguinis].	47.08	291	144	3	3	293	2	282	5e-80	256
rs:WP_023503058	methenyltetrahydrofolate cyclohydrolase/dehydrogenase [uncultured archaeon A07HN63].	47.22	288	150	2	5	292	4	289	5e-80	256
tr:S9UU80_PAEAL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.77	291	141	4	1	291	2	281	5e-80	256
rs:WP_002929708	bifunctional protein FolD [Streptococcus sanguinis].	46.74	291	145	3	3	293	2	282	6e-80	256
rs:XP_010931632	PREDICTED: bifunctional protein FolD 2 [Elaeis guineensis].	46.08	293	152	2	3	293	42	330	6e-80	257
rs:WP_015605554	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus oligofermentans].	47.77	291	142	3	3	293	2	282	6e-80	256
tr:L9KS54_TUPCH	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:ELW64012.1};	49.14	291	113	3	3	291	37	294	6e-80	256
rs:WP_013338749	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia sp. CCGE1003].	50.17	291	134	4	1	291	1	280	6e-80	256
rs:WP_002508035	tetrahydrofolate dehydrogenase [Staphylococcus sp. OJ82].	45.86	290	146	3	1	290	1	279	6e-80	256
tr:A0A0D3CKW3_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo5g133510.1};	45.24	294	155	2	2	293	7	296	6e-80	256
rs:WP_026074877	hypothetical protein [Bacteroidales bacterium ph8].	49.65	284	134	2	3	286	2	276	6e-80	256
rs:WP_016177068	FolD protein [Enterococcus durans].	48.61	288	137	4	3	290	2	278	6e-80	255
rs:WP_015344573	bifunctional protein folD [Candidatus Blochmannia chromaiodes].	45.14	288	148	2	1	288	1	278	6e-80	256
rs:XP_012600244	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Microcebus murinus].	48.28	290	143	3	11	294	1	289	6e-80	256
rs:WP_010597392	methenyltetrahydrofolate cyclohydrolase [Diplorickettsia massiliensis].	44.14	290	152	2	1	290	1	280	6e-80	256
rs:WP_034194560	bifunctional protein FolD [Burkholderia sp. WP42].	48.63	292	139	3	1	292	1	281	6e-80	256
rs:WP_033866060	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas aeruginosa].	51.35	259	116	2	32	290	1	249	6e-80	254
rs:WP_017224950	5,10-methylene-tetrahydrofolate dehydrogenase [Cupriavidus basilensis].	46.23	292	146	3	1	292	1	281	6e-80	255
sp:FOLD_POLSJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.45	291	139	4	1	291	1	280	6e-80	255
rs:WP_002480493	FolD protein [Staphylococcus simulans].	46.55	290	144	3	1	290	1	279	6e-80	256
rs:WP_008312238	5,10-methylene-tetrahydrofolate dehydrogenase [Haloarcula amylolytica].	46.85	286	150	2	5	290	4	287	6e-80	256
rs:WP_034368113	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter sp. MIT 03-1614].	46.67	285	141	3	5	289	3	276	6e-80	256
rs:WP_022015765	bifunctional protein FolD [Bacteroides sp. CAG:545].	48.59	284	137	3	3	286	2	276	6e-80	256
rs:WP_031837893	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	6e-80	256
rs:WP_037082537	methenyltetrahydrofolate cyclohydrolase [Pseudoxanthomonas sp. J35].	50.00	292	134	3	1	290	19	300	6e-80	256
sp:FOLD_BURVG	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.63	292	139	3	1	292	1	281	6e-80	255
rs:WP_000225831	tetrahydrofolate dehydrogenase [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	6e-80	256
rs:WP_003068208	tetrahydrofolate dehydrogenase [Streptococcus intermedius].	47.24	290	143	2	4	293	3	282	6e-80	255
rs:WP_002448150	tetrahydrofolate dehydrogenase [Staphylococcus hominis].	48.45	291	137	5	1	290	1	279	6e-80	255
rs:WP_042899186	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus].	45.21	292	149	3	1	292	1	281	6e-80	255
rs:WP_047132382	methenyltetrahydrofolate cyclohydrolase [Staphylococcus condimenti].	46.55	290	144	3	1	290	1	279	7e-80	255
sp:FOLD_STRGC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.08	291	144	3	3	293	2	282	7e-80	255
rs:WP_015171400	5,10-methylene-tetrahydrofolate dehydrogenase [Geitlerinema sp. PCC 7407].	45.26	285	150	2	2	286	5	283	7e-80	256
rs:WP_004965995	5,10-methylene-tetrahydrofolate dehydrogenase [Haloarcula sinaiiensis].	46.67	285	150	2	5	289	4	286	7e-80	256
rs:WP_002900895	tetrahydrofolate dehydrogenase [Streptococcus sanguinis].	46.74	291	145	3	3	293	2	282	7e-80	255
rs:WP_024785246	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mutans].	49.31	290	137	2	4	293	3	282	7e-80	255
rs:WP_044471225	methenyltetrahydrofolate cyclohydrolase [Wolbachia endosymbiont of Drosophila suzukii].	48.60	286	136	3	5	289	4	279	7e-80	256
rs:WP_007704658	5,10-methylene-tetrahydrofolate dehydrogenase [Halovivax asiaticus].	47.74	287	148	2	3	289	2	286	7e-80	256
rs:WP_018902811	bifunctional protein FolD [Variovorax paradoxus].	48.29	292	140	3	1	292	1	281	7e-80	255
sp:FOLD_TREPA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.52	292	160	1	1	292	1	290	7e-80	256
rs:WP_009022721	5,10-methylene-tetrahydrofolate dehydrogenase [gamma proteobacterium NOR5-3].	48.98	294	143	4	1	292	1	289	7e-80	256
rs:WP_000225832	bifunctional protein FolD [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	7e-80	255
rs:XP_008235030	PREDICTED: bifunctional protein FolD 2-like isoform X2 [Prunus mume].	45.86	290	151	2	3	290	9	294	7e-80	256
rs:XP_003573532	PREDICTED: bifunctional protein FolD 4, chloroplastic [Brachypodium distachyon].	47.26	292	148	2	2	291	83	370	7e-80	258
rs:WP_021974710	bifunctional protein FolD [Firmicutes bacterium CAG:884].	46.37	289	140	4	5	293	2	275	7e-80	255
rs:WP_021749080	MULTISPECIES: tetrahydrofolate dehydrogenase [Oscillibacter].	48.95	286	132	4	6	291	5	276	7e-80	255
rs:WP_027775442	methenyltetrahydrofolate cyclohydrolase [Burkholderia caledonica].	49.48	291	136	4	1	291	1	280	7e-80	255
rs:WP_006280028	bifunctional protein FolD [Wolbachia endosymbiont of Muscidifurax uniraptor].	48.25	286	137	3	5	289	4	279	7e-80	256
rs:WP_002915689	bifunctional protein FolD [Streptococcus sanguinis].	46.74	291	145	3	3	293	2	282	7e-80	255
rs:WP_022773184	5,10-methylene-tetrahydrofolate dehydrogenase [Butyrivibrio sp. AE2015].	48.97	292	135	4	1	289	1	281	8e-80	255
rs:WP_034943338	methenyltetrahydrofolate cyclohydrolase [Gilliamella apicola].	49.66	292	134	4	1	291	1	280	8e-80	255
rs:XP_008808389	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X1 [Phoenix dactylifera].	46.58	292	150	2	2	291	69	356	8e-80	258
rs:WP_029379098	methenyltetrahydrofolate cyclohydrolase [Staphylococcus xylosus].	45.52	290	147	3	1	290	1	279	8e-80	255
rs:WP_002896145	tetrahydrofolate dehydrogenase [Streptococcus sanguinis].	46.74	291	145	3	3	293	2	282	8e-80	255
rs:WP_027424131	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium AC3007].	49.31	288	137	3	3	290	2	280	8e-80	255
rs:WP_026825742	5,10-methylene-tetrahydrofolate cyclohydrolase [Exiguobacterium marinum].	48.79	289	135	4	3	291	2	277	8e-80	255
sp:FOLD_BURCH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.45	291	139	3	1	291	1	280	8e-80	255
rs:WP_028365838	methenyltetrahydrofolate cyclohydrolase [Burkholderia sp. UYPR1.413].	48.95	286	135	4	1	286	1	275	8e-80	255
rs:WP_045240081	methenyltetrahydrofolate cyclohydrolase [Burkholderiaceae bacterium 16].	45.89	292	147	3	1	292	1	281	8e-80	255
rs:WP_000225834	bifunctional protein FolD [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	8e-80	255
rs:WP_023477455	methylenetetrahydrofolate dehydrogenase [Burkholderia cenocepacia].	48.45	291	139	3	1	291	1	280	8e-80	255
rs:XP_005847387	hypothetical protein CHLNCDRAFT_52464 [Chlorella variabilis].	45.42	295	155	2	1	293	1	291	8e-80	256
rs:XP_012156704	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Ceratitis capitata].	47.96	294	146	3	3	290	34	326	8e-80	257
rs:WP_001656190	bifunctional protein FolD [Staphylococcus aureus].	45.17	290	148	3	1	290	1	279	8e-80	255
rs:WP_033848707	bifunctional protein FolD [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	8e-80	255
rs:WP_005881074	5,10-methylene-tetrahydrofolate dehydrogenase [Enterococcus durans].	48.61	288	137	4	3	290	2	278	8e-80	255
tr:I2DNR0_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.63	292	139	3	1	292	21	301	8e-80	256
rs:WP_004046209	5,10-methylene-tetrahydrofolate dehydrogenase [Halorubrum saccharovorum].	49.48	287	141	4	4	289	13	296	9e-80	256
rs:WP_000225842	bifunctional protein FolD [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	9e-80	255
rs:XP_012546309	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Bombyx mori].	47.12	295	147	5	3	290	34	326	9e-80	257
rs:WP_003709866	tetrahydrofolate dehydrogenase [Lactobacillus salivarius].	48.12	293	141	3	1	293	1	282	9e-80	255
rs:WP_025372632	methenyltetrahydrofolate cyclohydrolase [Advenella mimigardefordensis].	45.89	292	147	3	1	292	1	281	9e-80	255
rs:WP_027793485	methenyltetrahydrofolate cyclohydrolase [Burkholderia acidipaludis].	48.95	286	135	3	1	286	1	275	9e-80	255
rs:WP_004798943	5,10-methylene-tetrahydrofolate dehydrogenase [[Eubacterium] dolichum].	48.28	290	139	4	3	291	2	281	9e-80	255
tr:X4B6N7_SALEN	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:AHT06674.1}; Flags: Fragment;	50.93	269	122	3	1	269	1	259	9e-80	254
rs:WP_043242008	methenyltetrahydrofolate cyclohydrolase [Bosea sp. LC85].	49.13	287	136	2	2	288	4	280	9e-80	255
rs:WP_009632209	5,10-methylene-tetrahydrofolate dehydrogenase [Synechocystis sp. PCC 7509].	46.34	287	149	2	2	288	4	285	9e-80	255
rs:XP_007179895	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Balaenoptera acutorostrata scammoni].	48.28	290	143	3	11	294	1	289	9e-80	255
tr:Q1Q648_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.79	297	154	2	1	290	1	297	9e-80	256
tr:C7NDD5_LEPBD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.83	290	148	3	5	293	9	287	9e-80	255
rs:WP_029549734	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	9e-80	255
rs:WP_046568523	methenyltetrahydrofolate cyclohydrolase [Burkholderia fungorum].	49.30	286	134	4	1	286	1	275	9e-80	255
rs:XP_009790045	PREDICTED: bifunctional protein FolD 2-like [Nicotiana sylvestris].	46.08	293	152	2	3	293	9	297	9e-80	256
rs:WP_021338634	tetrahydrofolate dehydrogenase [Staphylococcus equorum].	45.86	290	146	3	1	290	1	279	9e-80	255
gp:CP002422_1890	methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase [Neisseria meningitidis M01-240355]	52.38	252	110	2	38	289	1	242	9e-80	254
rs:WP_041760721	5,10-methylene-tetrahydrofolate cyclohydrolase [Leptotrichia buccalis].	44.83	290	148	3	5	293	3	281	9e-80	255
rs:WP_020006259	hypothetical protein [Salinicoccus albus].	47.24	290	140	4	1	290	1	277	9e-80	255
rs:WP_006168878	5,10-methylene-tetrahydrofolate dehydrogenase [Natrialba chahannaoensis].	46.50	286	151	2	4	289	3	286	1e-79	255
sp:FOLD_STAAR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.52	290	147	3	1	290	1	279	1e-79	255
rs:WP_018004315	5,10-methylene-tetrahydrofolate dehydrogenase [Cupriavidus taiwanensis].	46.23	292	146	3	1	292	1	281	1e-79	255
rs:WP_026761236	5,10-methylene-tetrahydrofolate cyclohydrolase [Selenomonas ruminantium].	46.92	292	143	3	1	290	1	282	1e-79	255
rs:WP_009904650	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia thailandensis].	50.00	286	132	4	1	286	1	275	1e-79	255
sp:FOLD_BURTA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.65	286	133	4	1	286	1	275	1e-79	255
rs:XP_009146620	PREDICTED: bifunctional protein FolD 2-like [Brassica rapa].	45.24	294	155	2	2	293	7	296	1e-79	255
rs:WP_024647890	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.96	294	145	3	1	294	1	286	1e-79	255
tr:G3NLI9_GASAC	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGACP00000006202}; Flags: Fragment;	47.70	304	146	4	2	293	31	333	1e-79	256
rs:WP_013435736	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia rhizoxinica].	47.95	292	141	4	1	292	1	281	1e-79	255
rs:WP_018608340	hypothetical protein [Uliginosibacterium gangwonense].	46.76	293	145	4	1	293	1	282	1e-79	255
sp:FOLD_NATPD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.80	286	153	2	4	289	3	286	1e-79	255
rs:WP_002898021	bifunctional protein FolD [Streptococcus sanguinis].	46.74	291	145	3	3	293	2	282	1e-79	255
gp:AY085538_1	5,10-methylenetetrahydrofolate dehydrogenase:5,10-methenyltetrahydrofolate cyclohydrolase, putative [Arabidopsis thaliana]	44.18	292	157	2	2	291	8	295	1e-79	255
rs:XP_005798527	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2-like [Xiphophorus maculatus].	46.98	298	151	3	2	293	55	351	1e-79	257
sp:FOLD_STAS1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.86	290	146	3	1	290	1	279	1e-79	255
rs:WP_007623343	methylenetetrahydrofolate dehydrogenase [Paraglaciecola arctica].	46.39	291	146	2	1	291	1	281	1e-79	255
sp:FOLD_STAAB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.52	290	147	3	1	290	1	279	1e-79	255
rs:XP_011941660	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC105597730 [Cercocebus atys].	48.46	293	144	3	5	291	304	595	1e-79	266
rs:WP_041062917	methenyltetrahydrofolate cyclohydrolase [symbiont bacterium UwTKB of Urostylis westwoodii].	44.44	288	149	4	1	288	1	277	1e-79	255
rs:WP_031869092	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	1e-79	255
rs:WP_038678259	methenyltetrahydrofolate cyclohydrolase [Staphylococcus xylosus].	45.17	290	148	3	1	290	1	279	1e-79	255
sp:FOLD_HELHP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.67	285	141	3	5	289	3	276	1e-79	255
rs:XP_006407346	hypothetical protein EUTSA_v10021228mg [Eutrema salsugineum].	45.58	294	154	2	2	293	8	297	1e-79	255
rs:WP_009659972	tetrahydrofolate dehydrogenase [Streptococcus sp. AS14].	47.08	291	144	3	3	293	2	282	1e-79	255
rs:WP_028199475	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Burkholderia].	49.30	286	134	4	1	286	1	275	1e-79	255
rs:WP_031586074	5,10-methylene-tetrahydrofolate cyclohydrolase [Selenomonas bovis].	47.08	291	148	2	1	289	1	287	1e-79	255
rs:WP_024647130	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	50.00	286	135	3	1	286	1	278	1e-79	255
tr:A0A077UIG0_STAAU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.52	290	147	3	1	290	1	279	1e-79	255
rs:WP_014896614	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia cepacia].	49.30	286	134	3	1	286	1	275	1e-79	255
rs:WP_045634697	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	47.08	291	144	3	3	293	2	282	1e-79	255
rs:WP_028115210	methenyltetrahydrofolate cyclohydrolase [Ferrimonas senticii].	46.76	293	148	3	1	292	1	286	1e-79	255
rs:WP_002512259	tetrahydrofolate dehydrogenase [Staphylococcus equorum].	45.86	290	146	3	1	290	1	279	1e-79	255
rs:WP_002462683	tetrahydrofolate dehydrogenase [Staphylococcus simiae].	46.55	290	144	3	1	290	1	279	1e-79	255
rs:WP_009350237	5,10-methylene-tetrahydrofolate dehydrogenase [Selenomonas artemidis].	48.62	290	136	4	3	290	2	280	1e-79	255
rs:WP_004284009	methenyltetrahydrofolate cyclohydrolase [Neisseria weaveri].	47.95	292	138	3	1	290	1	280	1e-79	255
sp:FOLD_AZOSB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.10	293	146	5	1	292	1	285	1e-79	255
rs:WP_000225841	tetrahydrofolate dehydrogenase [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	1e-79	255
tr:A0A075MRT8_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.77	291	138	4	1	289	1	279	1e-79	254
rs:WP_008727966	5,10-methylene-tetrahydrofolate dehydrogenase [Erysipelotrichaceae bacterium 2_2_44A].	47.40	289	138	4	5	291	4	280	1e-79	254
rs:XP_008539339	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Equus przewalskii].	47.59	290	145	3	11	294	1	289	1e-79	255
sp:FOLD_ERYLH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.60	292	149	1	1	292	1	288	1e-79	255
rs:XP_005738223	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Pundamilia nyererei].	46.82	299	152	3	2	294	20	317	1e-79	256
rs:WP_027840517	methenyltetrahydrofolate cyclohydrolase [Mastigocoleus testarum].	47.78	293	148	2	1	292	1	289	1e-79	255
rs:WP_031886270	bifunctional protein FolD [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	1e-79	254
rs:WP_022419602	bifunctional protein FolD [Acidiphilium sp. CAG:727].	45.86	290	146	3	5	293	3	282	1e-79	254
rs:WP_000225847	tetrahydrofolate dehydrogenase [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	1e-79	254
rs:WP_017380065	hypothetical protein [Paenisporosarcina sp. TG-14].	44.71	293	151	4	1	293	1	282	1e-79	254
rs:XP_004960265	PREDICTED: bifunctional protein FolD 2 [Setaria italica].	46.42	293	151	2	3	293	2	290	1e-79	255
rs:WP_021689553	bifunctional protein FolD [Novosphingobium tardaugens].	49.32	292	144	1	1	292	1	288	1e-79	255
tr:A0A0E0VMZ3_STAA5	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:AFH69282.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AFH69282.1}; EC=3.5.4.9 {ECO:0000313|EMBL:AFH69282.1};	45.52	290	147	3	1	290	9	287	1e-79	255
rs:WP_045266837	methenyltetrahydrofolate cyclohydrolase [Comamonas aquatica].	49.48	289	130	5	1	286	1	276	1e-79	254
rs:WP_039067601	methenyltetrahydrofolate cyclohydrolase [Staphylococcus xylosus].	45.52	290	147	3	1	290	1	279	1e-79	254
rs:WP_033842209	methenyltetrahydrofolate cyclohydrolase, partial [Staphylococcus aureus].	45.86	290	146	3	1	290	1	279	1e-79	254
tr:A2VX15_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.45	291	139	3	1	291	23	302	1e-79	255
rs:WP_005590867	tetrahydrofolate dehydrogenase [Streptococcus cristatus].	47.77	291	142	3	3	293	2	282	1e-79	254
rs:WP_021067702	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Exiguobacterium].	48.44	289	136	4	3	291	2	277	1e-79	254
rs:WP_028020326	5,10-methylene-tetrahydrofolate cyclohydrolase [Enterococcus raffinosus].	47.08	291	143	4	3	293	2	281	1e-79	254
rs:WP_039646375	methenyltetrahydrofolate cyclohydrolase [Staphylococcus hyicus].	47.42	291	140	5	1	290	1	279	1e-79	254
rs:WP_025404910	methenyltetrahydrofolate cyclohydrolase [Burkholderia thailandensis].	50.00	286	132	4	1	286	1	275	1e-79	254
rs:WP_037478424	methenyltetrahydrofolate cyclohydrolase [Sphaerotilus natans].	49.83	289	129	6	1	286	1	276	1e-79	254
rs:WP_000225850	tetrahydrofolate dehydrogenase [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	2e-79	254
rs:WP_012990888	tetrahydrofolate dehydrogenase [Staphylococcus lugdunensis].	48.11	291	138	5	1	290	1	279	2e-79	254
rs:XP_010340903	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Saimiri boliviensis boliviensis].	47.93	290	144	3	11	294	1	289	2e-79	254
tr:D3B6A7_POLPA	SubName: Full=Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase {ECO:0000313|EMBL:EFA82877.1};	47.08	291	142	3	3	291	8	288	2e-79	255
sp:FOLD_CLOPH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	51.56	289	129	4	3	291	2	279	2e-79	254
rs:WP_000225849	bifunctional protein FolD [Staphylococcus aureus].	45.86	290	146	3	1	290	1	279	2e-79	254
rs:WP_040127771	methenyltetrahydrofolate cyclohydrolase [Burkholderia cenocepacia].	48.45	291	139	3	1	291	1	280	2e-79	254
rs:WP_019399383	methenyltetrahydrofolate cyclohydrolase [Pseudoxanthomonas sp. GW2].	50.00	288	132	3	1	286	1	278	2e-79	254
rs:WP_028596095	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus assamensis].	45.12	297	151	4	1	297	1	285	2e-79	254
rs:WP_000225840	tetrahydrofolate dehydrogenase [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	2e-79	254
rs:WP_034895803	methenyltetrahydrofolate cyclohydrolase [Candidatus Accumulibacter sp. SK-11].	47.77	291	141	3	1	291	1	280	2e-79	254
rs:WP_023957041	3-oxoacyl-ACP reductase [Paenibacillus sp. JCM 10914].	46.55	290	144	3	2	291	3	281	2e-79	254
rs:WP_034937553	methenyltetrahydrofolate cyclohydrolase [Candidatus Accumulibacter sp. SK-12].	47.08	291	143	3	1	291	1	280	2e-79	254
rs:WP_028386383	methenyltetrahydrofolate cyclohydrolase [Legionella geestiana].	48.10	289	140	2	1	289	1	279	2e-79	254
rs:WP_037072891	methenyltetrahydrofolate cyclohydrolase [Pseudoxanthomonas suwonensis].	49.32	292	136	3	1	290	19	300	2e-79	255
rs:WP_023071724	methenyltetrahydrofolate cyclohydrolase [Leptolyngbya sp. Heron Island J].	46.71	289	149	2	3	291	2	285	2e-79	254
rs:WP_015594889	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus sp. 1NLA3E].	45.86	290	146	3	1	290	1	279	2e-79	254
rs:WP_031775755	bifunctional protein FolD [Staphylococcus aureus].	45.17	290	148	3	1	290	1	279	2e-79	254
rs:XP_010456228	PREDICTED: bifunctional protein FolD 4, chloroplastic-like [Camelina sativa].	45.70	291	152	2	3	291	59	345	2e-79	256
rs:WP_035409745	5,10-methylene-tetrahydrofolate cyclohydrolase [Exiguobacterium sp. RIT341].	46.55	290	143	3	1	290	1	278	2e-79	254
rs:WP_045773845	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus sanguinis].	46.74	291	145	3	3	293	2	282	2e-79	254
rs:WP_014424298	5,10-methylene-tetrahydrofolate dehydrogenase [Selenomonas ruminantium].	47.26	292	142	3	1	290	1	282	2e-79	254
rs:WP_019000992	methenyltetrahydrofolate cyclohydrolase [Succinimonas amylolytica].	47.08	291	143	4	1	291	1	280	2e-79	254
rs:XP_003058275	predicted protein [Micromonas pusilla CCMP1545].	45.73	293	152	3	3	292	39	327	2e-79	256
rs:WP_034902144	methenyltetrahydrofolate cyclohydrolase [Erythrobacter litoralis].	47.39	287	147	1	6	292	7	289	2e-79	255
rs:WP_014848444	bifunctional protein FolD [Zymomonas mobilis].	47.78	293	145	3	3	291	4	292	2e-79	254
rs:WP_014500482	bifunctional protein FolD [Zymomonas mobilis].	47.78	293	145	3	3	291	4	292	2e-79	254
rs:XP_007247240	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like isoform X1 [Astyanax mexicanus].	45.64	298	155	3	2	293	42	338	2e-79	256
rs:WP_003030188	MULTISPECIES: tetrahydrofolate dehydrogenase [Streptococcus].	48.11	291	141	3	3	293	2	282	2e-79	254
rs:WP_018369999	tetrahydrofolate dehydrogenase [Streptococcus marimammalium].	46.53	288	144	2	6	293	5	282	2e-79	254
rs:WP_003041430	tetrahydrofolate dehydrogenase [Streptococcus anginosus].	47.77	291	142	3	3	293	2	282	2e-79	254
rs:XP_010528882	PREDICTED: bifunctional protein FolD 4, chloroplastic [Tarenaya hassleriana].	47.60	292	147	2	2	291	73	360	2e-79	257
rs:XP_006898510	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Elephantulus edwardii].	46.90	290	147	3	11	294	1	289	2e-79	254
rs:WP_031880672	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	2e-79	254
rs:WP_028948659	5,10-methylene-tetrahydrofolate cyclohydrolase [Synechocystis sp. PCC 6714].	44.86	292	155	2	2	293	7	292	2e-79	254
tr:A8UW89_9AQUI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.55	290	143	3	5	293	10	288	2e-79	254
rs:XP_004306810	PREDICTED: bifunctional protein FolD 4, chloroplastic [Fragaria vesca subsp. vesca].	46.88	288	147	2	6	291	77	360	2e-79	257
rs:WP_008848529	5,10-methylene-tetrahydrofolate dehydrogenase [Halorubrum kocurii].	49.12	285	143	2	5	289	15	297	2e-79	255
rs:WP_013562978	5,10-methylene-tetrahydrofolate dehydrogenase [Isosphaera pallida].	48.12	293	145	2	1	293	1	286	2e-79	255
rs:WP_013123846	5,10-methylene-tetrahydrofolate dehydrogenase [Thiomonas intermedia].	48.81	295	135	5	1	292	1	282	2e-79	254
rs:WP_017637033	tetrahydrofolate dehydrogenase [Staphylococcus sp. E463].	45.52	290	147	3	1	290	1	279	2e-79	254
rs:WP_000225843	tetrahydrofolate dehydrogenase [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	2e-79	254
tr:A0A068MUZ1_SYNY4	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.86	292	155	2	2	293	9	294	2e-79	254
rs:WP_002478384	tetrahydrofolate dehydrogenase [Staphylococcus lugdunensis].	48.11	291	138	5	1	290	1	279	2e-79	254
sp:FOLD_STAHJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.55	290	144	3	1	290	1	279	2e-79	254
tr:F7A9J3_MONDO	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMODP00000023956};	48.28	290	143	3	11	294	1	289	2e-79	254
tr:A0A0E0KYK4_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC05G03310.1};	46.76	293	150	2	3	293	2	290	2e-79	254
rs:WP_045501917	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus gordonii].	47.08	291	144	3	3	293	2	282	2e-79	254
rs:WP_031548287	methenyltetrahydrofolate cyclohydrolase [Salinicoccus luteus].	47.93	290	138	5	1	290	1	277	2e-79	254
rs:WP_014947106	5,10-methylene-tetrahydrofolate dehydrogenase [Chlamydia psittaci].	46.18	288	149	3	5	291	2	284	2e-79	254
rs:WP_044321951	methenyltetrahydrofolate cyclohydrolase [Pseudomonas amygdali].	48.80	291	141	3	1	291	1	283	2e-79	254
rs:WP_036809262	5,10-methylene-tetrahydrofolate cyclohydrolase [Planomicrobium glaciei].	46.08	293	147	4	1	293	1	282	2e-79	254
rs:WP_007257493	5,10-methylene-tetrahydrofolate dehydrogenase [Natronolimnobius innermongolicus].	47.04	287	148	4	4	289	3	286	2e-79	254
rs:WP_000225844	bifunctional protein FolD [Staphylococcus aureus].	45.52	290	147	3	1	290	1	279	2e-79	254
rs:WP_029333069	5,10-methylene-tetrahydrofolate cyclohydrolase [Exiguobacterium oxidotolerans].	46.90	290	142	3	1	290	1	278	2e-79	254
rs:WP_029937194	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. UNC305MFCol5.2].	48.11	291	140	3	1	291	1	280	2e-79	254
rs:WP_022980092	5,10-methylene-tetrahydrofolate dehydrogenase [Ideonella sp. B508-1].	47.08	291	143	4	1	291	1	280	2e-79	254
rs:WP_047172609	methenyltetrahydrofolate cyclohydrolase [Staphylococcus xylosus].	45.52	290	147	3	1	290	1	279	2e-79	254
rs:WP_007435478	5,10-methylene-tetrahydrofolate dehydrogenase [Acetobacteraceae bacterium AT-5844].	47.75	289	137	3	1	289	1	275	2e-79	254
sp:FOLD_ZYMMO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.78	293	145	3	3	291	4	292	2e-79	254
rs:WP_027805642	methenyltetrahydrofolate cyclohydrolase, partial [Burkholderia cenocepacia].	47.95	292	141	3	1	292	1	281	2e-79	254
rs:WP_029016089	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [unclassified Alphaproteobacteria (miscellaneous)].	46.50	286	149	1	5	290	3	284	2e-79	254
rs:WP_010184166	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas sp. PAMC 26605].	47.77	291	141	2	1	291	1	280	2e-79	254
tr:F3J5W2_PSEAP	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.30	294	144	3	1	294	1	286	2e-79	254
tr:A0A0B7GM88_STRSA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.74	291	145	3	3	293	2	282	2e-79	254
rs:WP_013278687	5,10-methylene-tetrahydrofolate dehydrogenase [Acetohalobium arabaticum].	45.52	290	147	2	2	291	4	282	2e-79	254
rs:WP_046165884	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus gordonii].	46.74	291	145	3	3	293	2	282	2e-79	254
sp:FOLD_BURL3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.65	286	133	3	1	286	1	275	2e-79	254
rs:WP_036070022	5,10-methylene-tetrahydrofolate cyclohydrolase [Leptotrichia sp. oral taxon 225].	45.83	288	144	3	5	291	3	279	2e-79	254
tr:Q9ZTV0_PEA	SubName: Full=5,10-methylenetetrahydrofolate dehydrogenase-5,10-methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:AAD01907.1}; SubName: Full=5,10-methylenetetrahydrofolate dehydrogenase: 5,10-methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:CAB56756.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CAB56756.1};	45.39	293	154	2	3	293	2	290	2e-79	254
rs:WP_037571861	methenyltetrahydrofolate cyclohydrolase [Staphylococcus chromogenes].	46.21	290	145	3	1	290	1	279	2e-79	254
rs:WP_024834716	5,10-methylene-tetrahydrofolate cyclohydrolase [[Clostridium] josui].	48.44	289	138	3	1	289	1	278	2e-79	254
rs:WP_022291345	bifunctional protein FolD [Staphylococcus sp. CAG:324].	45.10	286	146	2	5	290	3	277	2e-79	254
rs:WP_045498974	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus cristatus].	47.42	291	143	3	3	293	2	282	3e-79	254
gpu:CP008874_1361	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase [Halanaeroarchaeum sulfurireducens]	45.92	294	156	3	5	297	4	295	3e-79	254
rs:WP_019703185	5,10-methylene-tetrahydrofolate dehydrogenase [Acidovorax avenae].	47.26	292	143	4	1	292	1	281	3e-79	254
gp:CP006656_3718	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase [Klebsiella pneumoniae JM45]	52.36	254	111	3	38	291	1	244	3e-79	253
rs:WP_021916421	bifunctional protein FolD [Firmicutes bacterium CAG:24].	48.45	291	139	4	3	293	2	281	3e-79	254
rs:WP_027088505	methenyltetrahydrofolate cyclohydrolase [[Clostridium] saccharogumia].	47.39	287	141	3	5	291	2	278	3e-79	254
rs:WP_004215580	5,10-methylene-tetrahydrofolate dehydrogenase [Natrialba magadii].	45.80	286	153	2	4	289	3	286	3e-79	254
rs:WP_040955392	5,10-methylene-tetrahydrofolate cyclohydrolase [Virgibacillus sp. SK37].	48.28	290	139	3	1	290	1	279	3e-79	254
rs:WP_044340047	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus aquimaris].	45.86	290	146	4	1	290	1	279	3e-79	254
rs:WP_046112360	5,10-methylene-tetrahydrofolate cyclohydrolase [Aquincola tertiaricarbonis].	48.25	286	138	3	1	286	1	276	3e-79	254
rs:WP_013106584	bifunctional protein FolD [Thiomonas arsenitoxydans].	48.81	295	135	5	1	292	1	282	3e-79	254
rs:WP_027068909	methenyltetrahydrofolate cyclohydrolase [Lysobacter defluvii].	49.30	286	133	3	3	286	6	281	3e-79	254
rs:XP_008991431	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X5 [Callithrix jacchus].	48.28	290	143	3	11	294	1	289	3e-79	254
sp:FOLD_BURCA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.11	291	140	3	1	291	1	280	3e-79	254
sp:FOLD2_MYXXD	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.15	297	142	4	1	296	1	286	3e-79	254
rs:WP_013588936	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia].	49.48	291	136	4	1	291	1	280	3e-79	254
rs:WP_002459455	tetrahydrofolate dehydrogenase [Staphylococcus lugdunensis].	47.77	291	139	5	1	290	1	279	3e-79	254
tr:U2WE62_9FUSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.83	288	144	3	5	291	17	293	3e-79	254
tr:A0A0A6PQY9_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.12	295	145	3	1	295	1	284	3e-79	254
rs:WP_015301014	5,10-methylene-tetrahydrofolate dehydrogenase [Halovivax ruber].	47.39	287	149	2	3	289	2	286	3e-79	254
rs:WP_023394011	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Halobonum tyrrellensis].	47.55	286	146	2	4	289	3	284	3e-79	254
rs:WP_010727891	FolD protein [Enterococcus faecium].	47.57	288	140	3	3	290	2	278	3e-79	254
rs:WP_005043467	5,10-methylene-tetrahydrofolate dehydrogenase [Halococcus salifodinae].	47.06	289	150	2	4	292	3	288	3e-79	254
rs:WP_006702547	tetrahydrofolate dehydrogenase [Granulicatella elegans].	48.46	293	133	6	5	294	4	281	3e-79	254
sp:FOLD_NITOC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.42	291	143	3	1	291	1	281	3e-79	254
rs:WP_024673616	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.96	294	145	3	1	294	1	286	3e-79	254
tr:G5NQ85_SALET	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.74	272	122	4	1	270	1	262	3e-79	253
sp:FOLD_ANADF	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.17	287	131	4	5	290	2	277	3e-79	254
rs:WP_004076565	5,10-methylene-tetrahydrofolate dehydrogenase [Methanoplanus limicola].	45.45	286	142	3	5	290	2	273	3e-79	253
rs:XP_003898808	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Papio anubis].	47.68	302	147	4	3	294	51	351	3e-79	256
rs:WP_022064379	MULTISPECIES: bifunctional protein FolD [Alistipes].	48.44	289	140	3	5	293	2	281	3e-79	254
sp:FOLD2_ARATH	RecName: Full=Bifunctional protein FolD 2; AltName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase 2; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9;	44.18	292	157	2	2	291	8	295	3e-79	254
rs:XP_011356473	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Pteropus vampyrus].	48.14	295	135	4	3	291	37	319	3e-79	256
rs:WP_019468145	tetrahydrofolate dehydrogenase [Staphylococcus sp. AL1].	45.86	290	146	3	1	290	1	279	3e-79	254
tr:A0A061RQN1_9CHLO	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:JAC75167.1};	46.08	293	152	2	3	293	82	370	3e-79	256
rs:WP_008325138	5,10-methylene-tetrahydrofolate dehydrogenase [Haloferax elongans].	50.00	288	142	2	5	292	4	289	3e-79	254
rs:WP_043570917	methenyltetrahydrofolate cyclohydrolase [Candidatus Accumulibacter sp. BA-93].	49.66	292	134	5	1	291	1	280	3e-79	254
rs:WP_014246340	5,10-methylene-tetrahydrofolate dehydrogenase [Blattabacterium punctulatus].	41.32	288	165	2	3	289	2	286	3e-79	254
tr:W5AB78_WHEAT	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Traes_1BS_C47E474E3.1};	45.73	293	153	2	3	293	2	290	3e-79	254
rs:WP_041226009	5,10-methylene-tetrahydrofolate cyclohydrolase [Crinalium epipsammum].	49.29	282	137	2	5	286	8	283	3e-79	254
rs:WP_025598759	methenyltetrahydrofolate cyclohydrolase [Burkholderia sp. WSM2230].	49.48	291	136	4	1	291	1	280	3e-79	254
rs:WP_046445164	hypothetical protein [Alistipes sp. N15.MGS-157].	48.44	289	140	3	5	293	2	281	3e-79	253
rs:WP_010140544	5,10-methylene-tetrahydrofolate dehydrogenase [Oceanicola sp. S124].	48.46	293	146	2	1	292	1	289	3e-79	254
tr:I3S043_MEDTR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AFK33635.1};	45.73	293	153	2	3	293	2	290	3e-79	254
rs:WP_015153463	5,10-methylene-tetrahydrofolate dehydrogenase [Chroococcidiopsis thermalis].	44.18	292	157	2	2	293	5	290	3e-79	254
rs:WP_024334010	methenyltetrahydrofolate cyclohydrolase [Desulfotignum balticum].	47.12	295	154	1	1	293	1	295	3e-79	254
rs:WP_028075222	hypothetical protein [Solirubrobacterales bacterium URHD0059].	47.59	290	141	3	1	290	1	279	3e-79	254
rs:WP_037061029	methenyltetrahydrofolate cyclohydrolase [Pseudoxanthomonas suwonensis].	49.32	292	136	3	1	290	19	300	3e-79	254
rs:WP_043383411	methenyltetrahydrofolate cyclohydrolase [Comamonas aquatica].	49.48	289	130	5	1	286	1	276	3e-79	254
rs:WP_032496659	5,10-methylene-tetrahydrofolate cyclohydrolase [Hydrogenivirga sp. 128-5-R1-1].	46.55	290	143	3	5	293	6	284	3e-79	254
rs:WP_040144583	methenyltetrahydrofolate cyclohydrolase [Burkholderia cenocepacia].	48.95	286	135	3	1	286	1	275	3e-79	253
rs:WP_016679784	methenyltetrahydrofolate cyclohydrolase, partial [Yersinia pestis].	51.16	258	116	3	34	291	1	248	3e-79	253
rs:WP_028363440	methenyltetrahydrofolate cyclohydrolase [Burkholderia sp. JPY366].	49.14	291	137	4	1	291	1	280	4e-79	254
rs:XP_009418922	PREDICTED: bifunctional protein FolD 2 [Musa acuminata subsp. malaccensis].	45.05	293	155	2	3	293	2	290	4e-79	254
rs:WP_041045480	methenyltetrahydrofolate cyclohydrolase [Wolbachia endosymbiont of Cimex lectularius].	48.97	290	136	4	3	289	2	282	4e-79	254
rs:WP_029918236	5,10-methylene-tetrahydrofolate cyclohydrolase [Pelobacter seleniigenes].	49.14	291	137	3	3	293	2	281	4e-79	253
rs:WP_006156000	5,10-methylene-tetrahydrofolate dehydrogenase [Cupriavidus basilensis].	45.89	292	147	3	1	292	1	281	4e-79	253
rs:WP_000225848	bifunctional protein FolD [Staphylococcus aureus].	45.17	290	148	3	1	290	1	279	4e-79	253
rs:WP_044849112	methenyltetrahydrofolate cyclohydrolase [Burkholderia sp. USM B20].	48.60	286	136	3	1	286	1	275	4e-79	253
rs:XP_011753512	PREDICTED: LOW QUALITY PROTEIN: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Macaca nemestrina].	47.78	293	146	3	5	291	264	555	4e-79	263
rs:WP_041100351	methenyltetrahydrofolate cyclohydrolase [Sulfuritalea hydrogenivorans].	45.39	293	149	3	1	293	1	282	4e-79	253
rs:XP_006479912	PREDICTED: bifunctional protein FolD 2-like [Citrus sinensis].	46.76	293	150	2	3	293	9	297	4e-79	254
tr:A0A078BH50_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.81	295	135	5	1	292	1	282	4e-79	253
rs:WP_008650432	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Cupriavidus].	47.77	291	141	3	1	291	1	280	4e-79	253
tr:A0A068UM70_COFCA	SubName: Full=Coffea canephora DH200=94 genomic scaffold, scaffold_40 {ECO:0000313|EMBL:CDP09630.1};	45.39	304	149	3	3	293	9	308	4e-79	254
rs:WP_029232030	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. VCB2006].	50.00	292	132	4	1	289	1	281	4e-79	254
rs:WP_015766332	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Accumulibacter phosphatis].	47.42	291	142	3	1	291	1	280	4e-79	253
tr:A0A0E0DM46_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI05G03500.1};	46.76	293	150	2	3	293	2	290	4e-79	254
rs:WP_026894099	5,10-methylene-tetrahydrofolate cyclohydrolase [Clostridiisalibacter paucivorans].	46.39	291	145	2	1	291	1	280	4e-79	253
rs:WP_015750679	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfohalobium retbaense].	46.81	282	139	2	5	286	3	273	4e-79	253
rs:WP_038489473	5,10-methylene-tetrahydrofolate cyclohydrolase [Janthinobacterium agaricidamnosum].	46.39	291	145	3	1	291	1	280	4e-79	253
rs:WP_034882952	methenyltetrahydrofolate cyclohydrolase [Gilliamella apicola].	47.77	291	141	3	1	291	1	280	4e-79	253
tr:E6PWA7_9ZZZZ	SubName: Full=Bifunctional protein folD {ECO:0000313|EMBL:CBH99214.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CBH99214.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CBH99214.1};	48.29	292	139	4	1	291	1	281	4e-79	253
rs:WP_013773660	tetrahydrofolate dehydrogenase [Melissococcus plutonius].	46.34	287	143	4	6	292	5	280	4e-79	253
rs:XP_012688511	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Clupea harengus].	46.53	303	148	2	2	291	29	330	4e-79	255
rs:WP_006572619	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudoflavonifractor capillosus].	48.97	290	134	4	1	290	1	276	4e-79	253
rs:WP_038804985	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus dentisani].	47.42	291	143	3	3	293	2	282	4e-79	253
rs:WP_006965922	bifunctional protein FolD [Desulfotignum phosphitoxidans].	47.12	295	154	1	1	293	1	295	4e-79	254
rs:WP_002298006	tetrahydrofolate dehydrogenase [Enterococcus faecium].	47.57	288	140	3	3	290	2	278	4e-79	253
rs:WP_034361007	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter sp. MIT 01-6451].	46.32	285	142	4	5	289	3	276	4e-79	253
rs:XP_012676385	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Clupea harengus].	45.30	298	156	3	2	293	46	342	4e-79	255
rs:WP_008417350	5,10-methylene-tetrahydrofolate dehydrogenase [Halalkalicoccus jeotgali].	46.96	296	154	3	3	297	2	295	4e-79	254
rs:WP_042705079	methenyltetrahydrofolate cyclohydrolase [Methanomicrobium mobile].	49.30	286	131	4	5	290	2	273	4e-79	253
rs:WP_029074873	methenyltetrahydrofolate cyclohydrolase [Kaistia adipata].	47.46	295	147	4	2	292	11	301	4e-79	254
rs:WP_024786201	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mutans].	49.31	290	137	2	4	293	3	282	4e-79	253
rs:WP_015166676	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudanabaena sp. PCC 7367].	46.32	285	147	2	2	286	3	281	4e-79	254
rs:WP_043856710	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus].	45.17	290	148	3	1	290	1	279	4e-79	253
rs:WP_028914969	methenyltetrahydrofolate cyclohydrolase [Pseudoxanthomonas sp. J31].	50.00	288	132	3	1	286	1	278	4e-79	253
rs:WP_038096907	methenyltetrahydrofolate cyclohydrolase [Thioalkalivibrio sp. HK1].	47.04	287	146	2	5	291	1	281	4e-79	254
sp:FOLD_OPITP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.39	287	147	2	5	290	3	286	4e-79	254
rs:WP_039104097	methenyltetrahydrofolate cyclohydrolase [Frischella perrara].	46.21	290	145	4	1	290	1	279	4e-79	253
rs:WP_006758933	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia ambifaria].	48.95	286	135	3	1	286	1	275	4e-79	253
rs:WP_018026600	hypothetical protein [Oligella urethralis].	46.53	288	143	3	1	288	1	277	4e-79	253
rs:WP_020065487	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia bryophila].	50.00	286	132	4	1	286	1	275	5e-79	253
rs:WP_035664671	methenyltetrahydrofolate cyclohydrolase, partial [Bradyrhizobium sp. Ec3.3].	49.83	289	139	2	1	289	1	283	5e-79	253
tr:T1DXA5_9HELI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.83	284	137	4	5	288	2	271	5e-79	253
rs:WP_013945333	5,10-methylene-tetrahydrofolate dehydrogenase [Treponema paraluiscuniculi].	44.18	292	161	1	1	292	1	290	5e-79	254
sp:FOLD_LAWIP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.36	291	157	1	1	289	1	291	5e-79	254
rs:WP_034550512	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter fennelliae].	46.83	284	137	4	5	288	3	272	5e-79	253
tr:A0A091VGK7_OPIHO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFR01895.1}; Flags: Fragment;	47.10	293	147	3	3	291	4	292	5e-79	253
rs:WP_003315528	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	47.96	294	145	3	1	294	1	286	5e-79	254
rs:XP_002453212	hypothetical protein SORBIDRAFT_04g001700 [Sorghum bicolor].	47.42	291	147	2	3	291	77	363	5e-79	256
rs:WP_043345220	methenyltetrahydrofolate cyclohydrolase [Cupriavidus basilensis].	45.89	292	147	3	1	292	1	281	5e-79	253
rs:WP_021955577	bifunctional protein FolD [Eubacterium sp. CAG:115].	49.66	290	132	3	1	290	1	276	5e-79	253
rs:WP_004272655	5,10-methylene-tetrahydrofolate dehydrogenase [Nitrospirillum amazonense].	47.28	294	147	2	3	292	2	291	5e-79	254
sp:FOLD_ACAM1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.83	290	153	2	2	291	5	287	5e-79	253
rs:WP_005746839	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas amygdali].	48.45	291	142	3	1	291	1	283	5e-79	254
rs:WP_007524746	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio sp. A2].	47.90	286	142	2	5	290	3	281	5e-79	253
rs:WP_019449253	5,10-methylene-tetrahydrofolate dehydrogenase [Cupriavidus sp. BIS7].	47.42	291	142	3	1	291	1	280	5e-79	253
rs:WP_022253402	bifunctional protein FolD [Firmicutes bacterium CAG:466].	48.62	290	138	4	1	290	1	279	5e-79	253
rs:WP_009657797	5,10-methylene-tetrahydrofolate dehydrogenase [Selenomonas sp. FOBRC9].	48.28	290	137	4	3	290	2	280	5e-79	253
rs:WP_015284563	5,10-methylene-tetrahydrofolate dehydrogenase [Methanoregula formicica].	48.79	289	133	3	3	291	2	275	5e-79	253
rs:WP_040093667	methenyltetrahydrofolate cyclohydrolase [Spiroplasma poulsonii].	47.18	284	140	2	3	286	4	277	5e-79	253
sp:FOLD_STRT2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.14	291	138	3	3	293	2	282	5e-79	253
rs:WP_034376217	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter suis].	45.55	292	142	5	5	293	3	280	6e-79	253
rs:WP_009438186	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Selenomonas].	48.62	290	136	4	3	290	2	280	6e-79	253
rs:WP_039233731	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus thermotolerans].	49.15	293	138	5	1	293	1	282	6e-79	253
rs:WP_039332990	methenyltetrahydrofolate cyclohydrolase [Novosphingobium subterraneum].	46.58	292	151	2	1	292	1	287	6e-79	253
rs:WP_010470826	methenyltetrahydrofolate cyclohydrolase [Acaryochloris sp. CCMEE 5410].	44.83	290	153	2	2	291	5	287	6e-79	253
sp:FOLD_EHRRW	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.45	291	141	3	1	289	1	284	6e-79	253
tr:K2CIW2_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.92	288	136	4	5	290	3	278	6e-79	253
rs:WP_022243785	bifunctional protein FolD [Roseburia sp. CAG:45].	47.57	288	140	4	3	290	2	278	6e-79	253
tr:G6CXQ5_DANPL	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EHJ73977.1};	46.15	299	152	4	3	294	2	298	6e-79	253
sp:FOLD_BLOPB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.14	288	148	2	1	288	1	278	6e-79	253
rs:WP_040030511	methenyltetrahydrofolate cyclohydrolase [Staphylococcus cohnii].	45.86	290	146	3	1	290	1	279	6e-79	253
rs:WP_012976369	5,10-methylene-tetrahydrofolate dehydrogenase [Azospirillum lipoferum].	48.26	288	139	3	5	290	12	291	6e-79	253
gp:CP003679_682	bifunctional protein FolD [Treponema pallidum subsp. pallidum str. Sea 81-4]	44.48	290	159	1	3	292	29	316	6e-79	255
rs:WP_021684581	tetrahydrofolate dehydrogenase [Selenomonas sp. oral taxon 892].	47.24	290	140	4	3	290	2	280	6e-79	253
tr:X1A2I6_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_L00094 {ECO:0000313|EMBL:GAG54461.1};	46.23	292	151	2	1	286	1	292	6e-79	254
tr:W6TYU4_9SPHI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.12	292	168	1	4	294	2	293	6e-79	253
rs:WP_000225839	bifunctional protein FolD [Staphylococcus aureus].	45.17	290	148	3	1	290	1	279	6e-79	253
rs:WP_041189842	methenyltetrahydrofolate cyclohydrolase [Burkholderia pseudomallei].	49.65	286	133	4	1	286	1	275	6e-79	253
rs:XP_002973598	hypothetical protein SELMODRAFT_99718, partial [Selaginella moellendorffii].	44.03	293	158	2	3	293	2	290	6e-79	253
tr:K9VZK8_9CYAN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.29	282	137	2	5	286	20	295	6e-79	253
rs:WP_000057220	tetrahydrofolate dehydrogenase [Streptococcus oralis].	47.77	291	142	3	3	293	2	282	6e-79	253
rs:WP_015878411	bifunctional protein FolD [Burkholderia pseudomallei].	49.65	286	133	4	1	286	1	275	6e-79	253
rs:WP_038768277	methenyltetrahydrofolate cyclohydrolase [Burkholderia pseudomallei].	49.65	286	133	4	1	286	1	275	6e-79	253
sp:FOLD_BURP1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.65	286	133	4	1	286	1	275	6e-79	253
rs:WP_003031287	MULTISPECIES: tetrahydrofolate dehydrogenase [Streptococcus anginosus group].	47.42	291	143	2	3	293	2	282	6e-79	253
rs:XP_005473634	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Oreochromis niloticus].	46.82	299	152	3	2	294	50	347	7e-79	255
gp:CP001752_675	bifunctional protein FolD [Treponema pallidum subsp. pallidum str. Chicago]	44.48	290	159	1	3	292	29	316	7e-79	255
rs:WP_042612477	methenyltetrahydrofolate cyclohydrolase [Stenotrophomonas maltophilia].	48.64	294	139	4	2	293	10	293	7e-79	253
rs:WP_045181631	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus].	45.17	290	148	3	1	290	1	279	7e-79	253
tr:W5AMU3_WHEAT	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Traes_1DS_BA49B767E.1};	45.73	293	153	2	3	293	2	290	7e-79	253
rs:WP_009217781	5,10-methylene-tetrahydrofolate dehydrogenase [Bacteroidetes oral taxon 274].	47.35	283	140	3	4	286	2	275	7e-79	253
rs:WP_034969817	5,10-methylene-tetrahydrofolate cyclohydrolase [Campylobacter mucosalis].	48.26	288	138	3	4	291	2	278	7e-79	253
rs:WP_043799368	methenyltetrahydrofolate cyclohydrolase [Arenimonas malthae].	50.52	287	130	3	1	285	1	277	7e-79	253
rs:WP_014750590	5,10-methylene-tetrahydrofolate dehydrogenase [Advenella kashmirensis].	45.55	292	148	3	1	292	1	281	7e-79	253
rs:WP_002324430	FolD protein [Enterococcus faecium].	47.57	288	140	3	3	290	2	278	7e-79	253
rs:WP_029708944	methenyltetrahydrofolate cyclohydrolase [Rhodoferax saidenbachensis].	48.81	293	139	5	2	291	6	290	7e-79	253
rs:WP_002333487	FolD protein [Enterococcus faecium].	47.57	288	140	3	3	290	2	278	7e-79	253
rs:WP_037018722	methenyltetrahydrofolate cyclohydrolase [Rhizobiales bacterium YIM 77505].	46.39	291	150	3	1	291	1	285	7e-79	253
rs:WP_036826711	hypothetical protein [Porphyromonadaceae bacterium COT-184 OH4590].	47.70	283	139	2	4	286	2	275	7e-79	253
rs:WP_002286660	MULTISPECIES: tetrahydrofolate dehydrogenase [Enterococcus].	47.57	288	140	3	3	290	2	278	7e-79	253
rs:WP_044195805	methenyltetrahydrofolate cyclohydrolase [Ehrlichia sp. HF].	48.28	290	142	4	5	293	4	286	7e-79	253
rs:WP_021695485	methylenetetrahydrofolate dehydrogenase [Loktanella cinnabarina].	48.63	292	144	2	1	292	1	286	7e-79	253
rs:WP_033933633	methenyltetrahydrofolate cyclohydrolase, partial [Vibrio cholerae].	51.43	245	109	3	47	291	1	235	7e-79	251
rs:WP_033162199	methenyltetrahydrofolate cyclohydrolase [Sharpea azabuensis].	46.55	290	145	3	4	293	2	281	7e-79	253
tr:H3DEU2_TETNG	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTNIP00000019035}; Flags: Fragment;	46.82	299	151	4	2	293	28	325	7e-79	254
rs:WP_022789754	5,10-methylene-tetrahydrofolate dehydrogenase [[Streptococcus] pleomorphus].	45.36	291	144	4	4	291	2	280	7e-79	253
rs:XP_002975620	hypothetical protein SELMODRAFT_415851 [Selaginella moellendorffii].	44.03	293	158	2	3	293	8	296	8e-79	253
tr:A0A088MXJ8_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.05	291	147	3	1	291	3	283	8e-79	253
rs:WP_000057218	tetrahydrofolate dehydrogenase [Streptococcus mitis].	47.77	291	142	3	3	293	2	282	8e-79	253
rs:WP_018121730	hypothetical protein [Wohlfahrtiimonas chitiniclastica].	49.82	285	136	3	5	289	2	279	8e-79	253
tr:A0A031IKV3_9BACL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.53	288	142	3	3	290	2	277	8e-79	252
rs:WP_008534097	MULTISPECIES: tetrahydrofolate dehydrogenase [Streptococcus].	47.57	288	141	3	5	292	4	281	8e-79	253
rs:WP_041460316	5,10-methylene-tetrahydrofolate dehydrogenase [Chlamydia psittaci].	45.83	288	150	3	5	291	2	284	8e-79	253
rs:WP_024636551	5,10-methylene-tetrahydrofolate cyclohydrolase [Enterococcus faecium].	47.57	288	140	3	3	290	2	278	8e-79	253
rs:WP_034211292	methenyltetrahydrofolate cyclohydrolase [Arenimonas metalli].	50.00	294	135	3	1	292	1	284	8e-79	253
rs:WP_004047596	hypothetical protein [Lactobacillus murinus].	46.88	288	142	3	5	292	4	280	8e-79	253
rs:WP_036557053	methenyltetrahydrofolate cyclohydrolase [Oligella urethralis].	45.55	292	148	3	1	292	1	281	8e-79	253
rs:WP_027212049	methenyltetrahydrofolate cyclohydrolase [Burkholderia sp. WSM2232].	49.48	291	136	4	1	291	1	280	8e-79	253
rs:WP_028465380	methenyltetrahydrofolate cyclohydrolase [Nisaea denitrificans].	47.42	291	148	2	2	291	3	289	8e-79	253
rs:WP_034951194	methenyltetrahydrofolate cyclohydrolase [Candidatus Accumulibacter sp. SK-02].	47.42	291	143	2	1	291	1	281	8e-79	253
rs:WP_022352794	bifunctional protein FolD [Bacteroides sp. CAG:875].	59.28	194	79	0	101	294	1	194	8e-79	249
rs:WP_010619909	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus malefermentans].	47.96	294	136	6	3	292	2	282	8e-79	253
rs:XP_009135224	PREDICTED: bifunctional protein FolD 2 [Brassica rapa].	45.24	294	155	2	2	293	9	298	8e-79	253
rs:WP_038499469	methenyltetrahydrofolate cyclohydrolase [Candidatus Baumannia cicadellinicola].	46.05	291	147	3	1	291	1	281	8e-79	253
rs:WP_031921818	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus].	45.17	290	148	3	1	290	1	279	8e-79	253
rs:WP_006051253	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia].	50.35	286	131	4	1	286	1	275	8e-79	253
rs:WP_019167841	tetrahydrofolate dehydrogenase [Staphylococcus intermedius].	44.83	290	149	3	1	290	1	279	8e-79	253
rs:WP_045808920	methenyltetrahydrofolate cyclohydrolase [Candidatus Neoehrlichia lotoris].	49.66	292	139	3	1	291	1	285	8e-79	253
sp:FOLD_BURCM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.95	286	135	3	1	286	1	275	8e-79	253
rs:WP_006329324	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. STM 4661].	49.15	295	134	5	3	289	2	288	9e-79	253
gp:CP000023_587	methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase [Streptococcus thermophilus LMG 18311]	49.14	291	138	3	3	293	6	286	9e-79	253
tr:E7FZU6_9HELI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.55	292	142	5	5	293	8	285	9e-79	253
rs:WP_016931330	MULTISPECIES: bifunctional protein FolD [Staphylococcus].	46.21	290	145	3	1	290	1	279	9e-79	253
rs:WP_002327169	FolD protein [Enterococcus faecium].	47.57	288	140	3	3	290	2	278	9e-79	253
rs:WP_024537655	methenyltetrahydrofolate cyclohydrolase [Comamonas badia].	46.23	292	146	4	1	292	1	281	9e-79	252
tr:D8NT95_RALSL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.90	286	138	3	1	286	1	275	9e-79	253
rs:NP_001140502	uncharacterized protein LOC100272563 [Zea mays].	46.42	293	151	2	3	293	2	290	9e-79	253
rs:WP_038725371	methenyltetrahydrofolate cyclohydrolase [Burkholderia pseudomallei].	49.65	286	133	4	1	286	1	275	9e-79	253
rs:WP_046836076	methenyltetrahydrofolate cyclohydrolase [Staphylococcus succinus].	44.83	290	149	3	1	290	1	279	9e-79	253
rs:WP_037525072	methenyltetrahydrofolate cyclohydrolase [Sphingomonas wittichii].	48.11	291	146	2	1	291	1	286	9e-79	253
rs:WP_006664250	5,10-methylene-tetrahydrofolate dehydrogenase [Natrialba aegyptia].	45.00	300	150	3	4	289	3	301	9e-79	253
rs:WP_012860642	5,10-methylene-tetrahydrofolate dehydrogenase [Sebaldella termitidis].	45.99	287	143	3	5	290	3	278	9e-79	253
rs:WP_027327373	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter pametensis].	45.26	285	145	4	6	290	4	277	9e-79	253
rs:WP_038799293	methenyltetrahydrofolate cyclohydrolase [Burkholderia pseudomallei].	49.65	286	133	4	1	286	1	275	9e-79	253
rs:WP_017980386	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas melonis].	46.74	291	144	3	1	291	1	280	9e-79	253
rs:WP_027799950	methenyltetrahydrofolate cyclohydrolase [Burkholderia dilworthii].	48.80	291	138	4	1	291	1	280	1e-78	253
rs:XP_004337878	tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)binding domain containing protein [Acanthamoeba castellanii str. Neff].	46.39	291	150	2	3	291	2	288	1e-78	253
rs:WP_018037912	hypothetical protein [alpha proteobacterium SCGC AB-629-F11].	44.26	296	156	3	3	293	2	293	1e-78	253
rs:WP_032113050	hypothetical protein [Candidatus Paracaedibacter symbiosus].	44.48	290	155	2	4	293	3	286	1e-78	253
tr:Q5WN02_ORYSJ	SubName: Full=Putative uncharacterized protein P0001A07.7 {ECO:0000313|EMBL:AAV32199.1}; SubName: Full=cDNA clone:J033131D02, full insert sequence {ECO:0000313|EMBL:BAG96118.1};	46.08	293	152	2	3	293	2	290	1e-78	253
rs:XP_009590694	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X1 [Nicotiana tomentosiformis].	46.10	295	153	2	2	294	66	356	1e-78	255
sp:FOLD_BURXL	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.65	286	133	4	1	286	1	275	1e-78	253
rs:XP_008209398	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Nasonia vitripennis].	47.28	294	147	3	3	290	28	319	1e-78	254
rs:WP_009252827	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Clostridiales].	50.00	288	133	4	3	290	2	278	1e-78	252
rs:WP_010287834	5,10-methylene-tetrahydrofolate dehydrogenase [Kurthia massiliensis].	45.55	292	148	4	2	293	8	288	1e-78	253
sp:FOLD_STACT	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.86	290	146	3	1	290	1	279	1e-78	252
rs:XP_004072193	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Oryzias latipes].	46.31	298	153	3	2	293	50	346	1e-78	254
rs:WP_014727381	tetrahydrofolate dehydrogenase [Streptococcus thermophilus].	48.80	291	139	3	3	293	2	282	1e-78	252
rs:WP_002329020	FolD protein [Enterococcus faecium].	47.22	288	141	3	3	290	2	278	1e-78	252
rs:WP_023440277	bifunctional protein FolD [Pediococcus pentosaceus].	47.44	293	141	5	3	293	2	283	1e-78	252
tr:F1Z4C4_9SPHN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.43	287	143	2	3	289	11	292	1e-78	253
tr:F6ZS18_XENTR	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSXETP00000013956}; Flags: Fragment;	48.65	296	144	5	3	291	37	331	1e-78	254
rs:WP_039017256	methenyltetrahydrofolate cyclohydrolase [Halocynthiibacter namhaensis].	48.12	293	147	2	1	292	1	289	1e-78	253
rs:WP_010544922	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas elodea].	47.60	292	142	3	1	292	1	281	1e-78	253
rs:WP_019300127	methenyltetrahydrofolate cyclohydrolase [Xanthomonas oryzae].	48.61	288	136	3	4	289	13	290	1e-78	253
rs:WP_028101775	5,10-methylene-tetrahydrofolate cyclohydrolase [Pseudoduganella violaceinigra].	47.60	292	142	4	1	292	1	281	1e-78	252
tr:A0A0D9ZUB5_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM05G03510.2};	46.42	293	151	2	3	293	2	290	1e-78	253
rs:WP_015207142	5,10-methylene-tetrahydrofolate dehydrogenase [Cylindrospermum stagnale].	47.37	285	144	2	2	286	5	283	1e-78	253
rs:WP_044969079	methenyltetrahydrofolate cyclohydrolase [Clostridiaceae bacterium MS3].	50.00	288	133	4	3	290	2	278	1e-78	252
rs:WP_034292539	methenyltetrahydrofolate cyclohydrolase [Herbaspirillum sp. RV1423].	47.60	292	142	3	1	292	1	281	1e-78	252
rs:WP_006682297	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Glomeribacter gigasporarum].	47.44	293	143	3	1	293	1	282	1e-78	252
rs:WP_045615442	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	47.24	290	143	3	4	293	3	282	1e-78	252
gpu:CP011144_42	methenyltetrahydrofolate cyclohydrolase [Pseudoxanthomonas suwonensis]	48.64	294	139	3	1	292	1	284	1e-78	252
sp:FOLD_XANOM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.61	288	136	3	4	289	13	290	1e-78	253
rs:WP_019542312	hypothetical protein [Selenomonas bovis].	46.05	291	151	2	1	289	1	287	1e-78	253
rs:WP_005951291	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium varium].	47.06	289	141	3	5	292	2	279	1e-78	252
rs:XP_012721111	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Fundulus heteroclitus].	46.64	298	152	3	2	293	50	346	1e-78	254
rs:WP_003093181	tetrahydrofolate dehydrogenase [Streptococcus vestibularis].	49.31	290	137	3	3	292	2	281	1e-78	252
rs:WP_031912485	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus].	45.17	290	148	3	1	290	1	279	1e-78	252
rs:WP_002341236	FolD protein [Enterococcus faecium].	47.22	288	141	3	3	290	2	278	1e-78	252
rs:WP_022526625	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus anginosus].	47.42	291	143	2	3	293	2	282	1e-78	252
rs:WP_041196045	methenyltetrahydrofolate cyclohydrolase [Burkholderia pseudomallei].	49.65	286	133	4	1	286	1	275	1e-78	252
rs:XP_005924534	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Haplochromis burtoni].	46.82	299	152	3	2	294	81	378	1e-78	255
tr:A0A0A1F923_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.38	260	119	2	32	291	7	256	1e-78	251
rs:WP_035447934	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus animalis].	47.57	288	140	3	5	292	4	280	1e-78	252
tr:B6T3G6_MAIZE	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:ACG31649.1};	46.08	293	152	2	3	293	2	290	1e-78	252
rs:XP_009393888	PREDICTED: bifunctional protein FolD 4, chloroplastic-like [Musa acuminata subsp. malaccensis].	45.89	292	152	2	2	291	65	352	1e-78	254
rs:WP_038561189	5,10-methylene-tetrahydrofolate cyclohydrolase [Terribacillus aidingensis].	45.80	286	144	3	1	286	1	275	1e-78	252
rs:WP_015178750	bifunctional protein FolD [Oscillatoria nigro-viridis].	46.69	287	143	3	2	286	5	283	1e-78	252
rs:WP_044105116	methenyltetrahydrofolate cyclohydrolase [secondary endosymbiont of Heteropsylla cubana].	46.39	291	146	2	1	291	1	281	1e-78	252
rs:XP_002776877	methylenetetrahydrofolate dehydrogenase, putative [Perkinsus marinus ATCC 50983].	50.17	291	135	3	1	285	1	287	1e-78	272
rs:WP_007418642	5,10-methylene-tetrahydrofolate dehydrogenase [Pedosphaera parvula].	48.10	289	148	2	3	290	4	291	1e-78	253
rs:WP_018075890	5,10-methylene-tetrahydrofolate dehydrogenase [Novosphingobium nitrogenifigens].	48.61	288	141	3	3	289	10	291	1e-78	253
rs:WP_037535546	bifunctional protein FolD [Staphylococcus haemolyticus].	46.21	290	145	3	1	290	1	279	1e-78	252
rs:WP_037049163	methenyltetrahydrofolate cyclohydrolase [Pseudomonas oleovorans].	48.14	295	145	3	1	295	1	287	1e-78	252
rs:WP_026858537	methenyltetrahydrofolate cyclohydrolase [Jeotgalicoccus psychrophilus].	46.55	290	142	5	1	290	1	277	1e-78	252
rs:WP_006025939	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia thailandensis].	49.65	286	133	4	1	286	1	275	1e-78	252
tr:F2DGN6_HORVD	SubName: Full=Predicted protein {ECO:0000313|EMBL:BAJ94257.1};	47.60	292	147	2	2	291	82	369	1e-78	255
rs:WP_024009803	tetrahydrofolate dehydrogenase [Streptococcus thermophilus].	48.80	291	139	3	3	293	2	282	1e-78	252
tr:A0A0C9QL14_9SPER	SubName: Full=TSA: Wollemia nobilis Ref_Wollemi_Transcript_29060_1230 transcribed RNA sequence {ECO:0000313|EMBL:JAG85300.1};	44.86	292	155	2	3	292	2	289	1e-78	252
rs:WP_009973803	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia pseudomallei].	49.30	286	134	4	1	286	1	275	1e-78	252
rs:XP_010941303	PREDICTED: bifunctional protein FolD 4, chloroplastic-like [Elaeis guineensis].	46.58	292	150	2	2	291	68	355	1e-78	254
sp:FOLD2_GEOSL	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.92	288	139	3	3	290	2	278	1e-78	252
rs:WP_042973627	methenyltetrahydrofolate cyclohydrolase [Burkholderia sp. AU4i].	48.60	286	136	3	1	286	1	275	1e-78	252
tr:V8LWY8_STRTR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.80	291	139	3	3	293	2	282	2e-78	252
rs:WP_014354297	methenyltetrahydrofolate cyclohydrolase [Wigglesworthia glossinidia].	43.71	286	151	2	1	286	1	276	2e-78	252
rs:WP_002968951	5,10-methylene-tetrahydrofolate dehydrogenase [Brucella abortus].	48.98	294	142	4	3	292	2	291	2e-78	252
rs:WP_047230650	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus].	45.17	290	148	3	1	290	1	279	2e-78	252
rs:WP_004088174	hypothetical protein [Helicobacter bilis].	44.95	287	147	4	5	291	8	283	2e-78	252
rs:WP_000057221	tetrahydrofolate dehydrogenase [Streptococcus oralis].	47.42	291	143	3	3	293	2	282	2e-78	252
sp:FOLD_BURA4	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.60	286	136	3	1	286	1	275	2e-78	252
sp:FOLD_AROAE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.77	291	145	4	1	291	1	284	2e-78	252
rs:WP_010688945	tetrahydrofolate dehydrogenase [Lactobacillus animalis].	47.57	288	140	3	5	292	4	280	2e-78	252
tr:W0JU39_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.20	286	149	2	4	289	3	286	2e-78	252
rs:WP_017317434	methenyltetrahydrofolate cyclohydrolase [Mastigocladopsis repens].	45.26	285	150	2	2	286	5	283	2e-78	252
rs:WP_032976153	methenyltetrahydrofolate cyclohydrolase [Stenotrophomonas sp. RIT309].	48.14	295	141	4	1	293	8	292	2e-78	252
tr:A0A0B8QYW2_LISMN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.41	283	135	4	9	291	4	275	2e-78	252
rs:WP_004410707	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	48.30	294	144	3	1	294	1	286	2e-78	252
rs:WP_010733365	FolD protein [Enterococcus faecium].	47.22	288	141	3	3	290	2	278	2e-78	252
rs:WP_025199477	bifunctional protein FolD [Brucella sp. BO2].	48.98	294	142	4	3	292	2	291	2e-78	252
tr:E2PN11_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.98	294	142	4	3	292	17	306	2e-78	253
rs:WP_041190785	methenyltetrahydrofolate cyclohydrolase [Burkholderia pseudomallei].	49.65	286	133	4	1	286	1	275	2e-78	252
rs:WP_036328784	5,10-methylene-tetrahydrofolate cyclohydrolase [Mollicutes bacterium HR2].	47.26	292	142	4	3	293	2	282	2e-78	252
rs:WP_031336365	bifunctional protein FolD [Xylella fastidiosa].	47.95	292	140	3	3	292	8	289	2e-78	252
rs:WP_022320928	bifunctional protein FolD [Clostridium sp. CAG:349].	47.92	288	139	4	4	291	2	278	2e-78	251
rs:WP_024722736	methenyltetrahydrofolate cyclohydrolase [Clostridiales bacterium VE202-01].	47.04	287	142	3	5	291	2	278	2e-78	252
rs:WP_018435406	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia sp. JPY251].	48.95	286	135	3	1	286	1	275	2e-78	252
sp:FOLD_WOLPM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.55	286	139	3	5	289	4	279	2e-78	252
rs:WP_002310266	tetrahydrofolate dehydrogenase [Enterococcus faecium].	47.22	288	141	3	3	290	2	278	2e-78	252
rs:WP_002375276	tetrahydrofolate dehydrogenase [Enterococcus faecium].	47.22	288	141	3	3	290	2	278	2e-78	252
rs:WP_002320037	tetrahydrofolate dehydrogenase [Enterococcus faecium].	47.22	288	141	3	3	290	2	278	2e-78	252
gp:CR555306_67	FolD bifunctional protein [Aromatoleum aromaticum EbN1]	47.77	291	145	4	1	291	23	306	2e-78	253
rs:WP_041018541	methenyltetrahydrofolate cyclohydrolase [Criblamydia sequanensis].	49.61	256	128	1	32	286	26	281	2e-78	252
rs:WP_019165606	tetrahydrofolate dehydrogenase [Staphylococcus delphini].	45.52	290	147	3	1	290	1	279	2e-78	252
rs:WP_039364793	methenyltetrahydrofolate cyclohydrolase [Mumia flava].	49.30	286	134	3	1	286	1	275	2e-78	252
rs:WP_018574924	hypothetical protein [Oligella ureolytica].	46.88	288	142	3	1	288	1	277	2e-78	252
rs:WP_008316501	bifunctional protein FolD [Wohlfahrtiimonas chitiniclastica].	50.18	285	135	3	5	289	2	279	2e-78	252
rs:WP_038731181	bifunctional protein FolD [Burkholderia pseudomallei].	49.30	286	134	4	1	286	1	275	2e-78	252
rs:WP_022664443	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfospira joergensenii].	46.44	295	156	1	1	293	1	295	2e-78	252
rs:XP_006444279	hypothetical protein CICLE_v10021378mg [Citrus clementina].	46.42	293	151	2	3	293	9	297	2e-78	252
rs:WP_042767767	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus].	47.42	291	143	3	3	293	2	282	2e-78	251
sp:FOLD_RALME	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.42	291	142	3	1	291	1	280	2e-78	251
rs:WP_009732408	FolD protein [Streptococcus sp. F0442].	48.10	289	140	3	5	293	4	282	2e-78	251
rs:WP_046428805	methenyltetrahydrofolate cyclohydrolase [Burkholderia vietnamiensis].	48.95	286	135	3	1	286	1	275	2e-78	251
rs:WP_044318769	methenyltetrahydrofolate cyclohydrolase [Pseudomonas amygdali].	48.11	291	143	3	1	291	1	283	2e-78	252
sp:FOLD_HALSA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.71	289	152	2	4	292	3	289	2e-78	252
rs:WP_000057226	tetrahydrofolate dehydrogenase [Streptococcus oralis].	47.42	291	143	3	3	293	2	282	2e-78	251
rs:WP_002965862	5,10-methylene-tetrahydrofolate dehydrogenase [Brucella abortus].	48.98	294	142	4	3	292	2	291	2e-78	252
rs:WP_025874985	methenyltetrahydrofolate cyclohydrolase [Stenotrophomonas maltophilia].	47.80	295	142	4	1	293	8	292	2e-78	252
sp:FOLD_XYLFT	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.95	292	140	3	3	292	8	289	2e-78	252
rs:WP_010728500	FolD protein [Enterococcus faecium].	47.22	288	141	3	3	290	2	278	2e-78	251
rs:WP_044752945	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.92	288	140	3	5	292	3	280	2e-78	251
rs:WP_000192101	tetrahydrofolate dehydrogenase [Streptococcus mitis].	47.24	290	143	3	4	293	3	282	2e-78	251
rs:WP_014614281	tetrahydrofolate dehydrogenase [Staphylococcus pseudintermedius].	45.52	290	147	3	1	290	1	279	2e-78	251
tr:U2FSZ2_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.60	286	136	3	1	286	24	298	2e-78	252
rs:WP_044361350	methenyltetrahydrofolate cyclohydrolase [Staphylococcus microti].	45.17	290	148	3	1	290	1	279	2e-78	251
rs:WP_045171074	methenyltetrahydrofolate cyclohydrolase [Ehrlichia mineirensis].	48.11	291	142	3	1	289	1	284	2e-78	252
rs:WP_020851519	bifunctional protein FolD [Xylella fastidiosa].	47.95	292	140	3	3	292	8	289	2e-78	252
rs:WP_004412563	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	47.96	294	145	3	1	294	1	286	2e-78	252
tr:A0A078C9R5_BRANA	SubName: Full=BnaA03g32210D protein {ECO:0000313|EMBL:CDX73826.1};	45.24	294	155	2	2	293	9	298	2e-78	252
sp:FOLD_BAUCH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.17	290	149	2	1	290	1	280	2e-78	251
rs:WP_034910856	methenyltetrahydrofolate cyclohydrolase [Candidatus Accumulibacter sp. BA-91].	47.28	294	145	2	1	294	1	284	2e-78	251
tr:D2TXF4_9ENTR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.26	281	141	3	11	291	2	272	2e-78	251
rs:WP_044308328	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.96	294	145	3	1	294	1	286	2e-78	252
rs:WP_038228132	bifunctional protein FolD [Xylella fastidiosa].	47.95	292	140	3	3	292	8	289	2e-78	251
rs:WP_012337993	bifunctional protein FolD [Xylella fastidiosa].	47.95	292	140	3	3	292	8	289	2e-78	251
rs:XP_011101984	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X2 [Sesamum indicum].	46.94	294	150	2	2	293	69	358	2e-78	254
rs:NP_001054668	Os05g0150800, partial [Oryza sativa Japonica Group].	46.08	293	152	2	3	293	39	327	2e-78	253
rs:WP_002510869	MULTISPECIES: tetrahydrofolate dehydrogenase [Staphylococcus].	45.17	290	148	3	1	290	1	279	2e-78	251
rs:WP_032614650	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.62	294	146	3	1	294	1	286	2e-78	252
rs:WP_022284830	bifunctional protein FolD [Bacteroides sp. CAG:770].	48.76	283	136	3	4	286	3	276	2e-78	251
rs:WP_039409743	methenyltetrahydrofolate cyclohydrolase [Xanthomonas campestris].	48.61	288	136	3	4	289	13	290	3e-78	252
rs:WP_016483642	5,10-methylene-tetrahydrofolate dehydrogenase [Chthonomonas calidirosea].	44.37	293	153	3	3	295	9	291	3e-78	252
rs:WP_022076089	bifunctional protein FolD [Firmicutes bacterium CAG:212].	47.92	288	139	4	4	291	2	278	3e-78	251
rs:WP_024745060	methenyltetrahydrofolate cyclohydrolase [Xanthomonas oryzae].	48.61	288	136	3	4	289	13	290	3e-78	252
rs:WP_007166044	5,10-methylene-tetrahydrofolate dehydrogenase [Erythrobacter sp. NAP1].	47.26	292	150	1	1	292	1	288	3e-78	252
rs:WP_021054493	5,10-methylene-tetrahydrofolate dehydrogenase [Haloquadratum walsbyi].	47.37	285	146	2	5	289	20	300	3e-78	252
gpu:CP009505_2359	Methylenetetrahydrofolate dehydrogenase (NADP+) [Methanosarcina sp. MTP4]	48.80	291	138	2	3	293	8	287	3e-78	251
rs:WP_042486986	methenyltetrahydrofolate cyclohydrolase [Sphingomonas parapaucimobilis].	47.24	290	142	3	2	291	3	281	3e-78	251
rs:WP_015547964	5,10-methylene-tetrahydrofolate dehydrogenase [Alistipes shahii].	47.54	284	140	3	3	286	2	276	3e-78	251
tr:W7VHP4_STRTR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.80	291	139	3	3	293	2	282	3e-78	251
rs:WP_038770393	methenyltetrahydrofolate cyclohydrolase [Burkholderia pseudomallei].	49.65	286	133	4	1	286	1	275	3e-78	251
sp:FOLD_STRTD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.45	291	140	3	3	293	2	282	3e-78	251
sp:FOLD_XYLFA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.95	292	140	3	3	292	12	293	3e-78	251
rs:WP_022247625	bifunctional protein FolD [Clostridium sp. CAG:306].	46.67	285	137	4	3	286	2	272	3e-78	251
rs:WP_007019977	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Neptuniibacter caesariensis].	49.81	263	122	2	30	292	9	261	3e-78	251
rs:WP_022092347	bifunctional protein FolD [Firmicutes bacterium CAG:536].	50.69	288	127	5	4	288	2	277	3e-78	251
rs:WP_038713522	methenyltetrahydrofolate cyclohydrolase [Burkholderia sp. lig30].	48.95	286	135	4	1	286	1	275	3e-78	251
rs:WP_038789662	methenyltetrahydrofolate cyclohydrolase [Burkholderia pseudomallei].	49.65	286	133	4	1	286	1	275	3e-78	251
rs:WP_009728534	hypothetical protein [Selenomonas sp. F0473].	48.28	290	137	4	3	290	2	280	3e-78	251
rs:WP_002291887	tetrahydrofolate dehydrogenase [Enterococcus faecium].	47.22	288	141	3	3	290	2	278	3e-78	251
rs:WP_043060972	methenyltetrahydrofolate cyclohydrolase [Sphingomonas taxi].	46.74	291	144	3	1	291	1	280	3e-78	251
rs:WP_024072298	5,10-methylene-tetrahydrofolate dehydrogenase [Ehrlichia muris].	47.77	291	144	4	4	293	3	286	3e-78	251
rs:WP_025369109	methenyltetrahydrofolate cyclohydrolase [Buchnera aphidicola].	43.30	291	155	2	1	291	1	281	3e-78	251
rs:WP_046270426	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.62	294	146	3	1	294	1	286	3e-78	252
rs:WP_046235892	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae pv. coryli].	47.62	294	146	3	1	294	1	286	3e-78	252
sp:FOLD_BURPP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.95	286	135	3	1	286	1	275	3e-78	251
gp:CP000124_2712	FolD bifunctional protein [Burkholderia pseudomallei 1710b]	49.65	286	133	4	1	286	41	315	3e-78	253
rs:XP_005401361	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Chinchilla lanigera].	46.98	298	151	3	3	294	46	342	3e-78	253
sp:FOLD_EHRRG	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.11	291	142	3	1	289	1	284	3e-78	252
rs:WP_014160871	methenyltetrahydrofolate cyclohydrolase [Pseudoxanthomonas spadix].	47.95	292	140	3	3	292	7	288	3e-78	251
rs:WP_043293272	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas sp. LAMO17WK12:I2].	48.43	287	141	2	2	288	8	287	3e-78	251
rs:WP_003423864	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	47.62	294	146	3	1	294	1	286	3e-78	251
rs:WP_023786160	5,10-methylene-tetrahydrofolate dehydrogenase [Hyphomicrobium nitrativorans].	47.93	290	145	2	1	290	1	284	3e-78	251
rs:WP_008445985	5,10-methylene-tetrahydrofolate dehydrogenase [Halorubrum californiense].	50.52	287	138	4	4	289	3	286	3e-78	251
rs:XP_007514825	predicted protein [Bathycoccus prasinos].	45.58	294	150	4	4	292	121	409	3e-78	255
rs:WP_043972203	methenyltetrahydrofolate cyclohydrolase [Novosphingobium sp. P6W].	47.95	292	147	2	2	293	3	289	3e-78	251
rs:WP_037565998	methenyltetrahydrofolate cyclohydrolase [Staphylococcus agnetis].	45.86	290	146	3	1	290	1	279	3e-78	251
rs:WP_002345576	FolD protein [Enterococcus faecium].	46.88	288	142	3	3	290	2	278	3e-78	251
rs:WP_000057231	tetrahydrofolate dehydrogenase [Streptococcus sp. oral taxon 058].	47.42	291	143	3	3	293	2	282	3e-78	251
rs:WP_044333760	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. WHSC-8].	46.58	292	145	3	1	292	1	281	3e-78	251
rs:WP_003097586	tetrahydrofolate dehydrogenase [Streptococcus vestibularis].	48.97	290	138	3	3	292	2	281	3e-78	251
rs:WP_043190380	methenyltetrahydrofolate cyclohydrolase [Burkholderia cepacia].	48.95	286	135	3	1	286	1	275	4e-78	251
rs:WP_039646130	5,10-methylene-tetrahydrofolate cyclohydrolase [Geobacter sp. GSS01].	47.57	288	140	3	3	290	2	278	4e-78	251
tr:A0A0D9YLG6_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM02G01450.1};	47.08	291	148	2	3	291	78	364	4e-78	254
rs:WP_026792475	methenyltetrahydrofolate cyclohydrolase [Pleomorphomonas oryzae].	49.15	293	142	3	1	293	1	286	4e-78	251
sp:FOLD_SYNFM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.83	290	159	1	1	290	1	289	4e-78	251
sp:FOLD_BURP0	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.30	286	134	4	1	286	1	275	4e-78	251
rs:XP_005401362	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Chinchilla lanigera].	46.98	298	151	3	3	294	37	333	4e-78	253
rs:WP_007687894	5,10-methylene-tetrahydrofolate dehydrogenase [Novosphingobium sp. AP12].	48.80	291	144	2	3	293	4	289	4e-78	251
rs:WP_017881266	bifunctional protein FolD [Burkholderia pseudomallei].	49.30	286	134	4	1	286	1	275	4e-78	251
rs:WP_027786958	methenyltetrahydrofolate cyclohydrolase [Burkholderia cepacia].	48.60	286	136	3	1	286	1	275	4e-78	251
rs:WP_046546067	methenyltetrahydrofolate cyclohydrolase [Burkholderia contaminans].	48.95	286	135	3	1	286	1	275	4e-78	251
rs:WP_000192086	tetrahydrofolate dehydrogenase [Streptococcus mitis].	47.24	290	143	3	4	293	3	282	4e-78	251
rs:WP_010767145	FolD protein [Enterococcus phoeniculicola].	47.59	290	141	4	3	292	2	280	4e-78	251
rs:WP_045762889	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	47.59	290	142	3	4	293	3	282	4e-78	251
tr:A0A0E0JUT4_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC02G01040.1};	46.74	291	149	2	3	291	24	310	4e-78	252
rs:WP_014313254	5,10-methylene-tetrahydrofolate dehydrogenase [Clostridium sp. BNL1100].	47.75	289	140	3	1	289	1	278	4e-78	251
rs:WP_039420257	methenyltetrahydrofolate cyclohydrolase [Xanthomonas vesicatoria].	48.96	288	135	3	4	289	13	290	4e-78	251
rs:WP_014449211	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospirillum ferrooxidans].	48.79	289	138	3	3	291	2	280	4e-78	251
tr:A0A0B0EGS4_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.18	301	147	4	1	290	1	297	4e-78	251
rs:XP_006854775	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X1 [Amborella trichopoda].	45.36	291	153	2	3	291	80	366	4e-78	254
rs:WP_010484605	methenyltetrahydrofolate cyclohydrolase [Stenotrophomonas maltophilia].	48.63	292	138	4	3	292	10	291	4e-78	251
rs:WP_005660808	5,10-methylene-tetrahydrofolate dehydrogenase [Dethiosulfovibrio peptidovorans].	45.70	291	146	3	1	291	1	279	4e-78	251
tr:B6SJR7_MAIZE	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:ACG25100.1};	46.74	291	149	2	3	291	78	364	4e-78	254
rs:WP_019086347	hypothetical protein [Komagataeibacter europaeus].	47.62	294	146	3	1	293	6	292	4e-78	251
rs:WP_038198894	methenyltetrahydrofolate cyclohydrolase [Wolbachia pipientis].	47.55	286	139	3	5	289	4	279	4e-78	251
rs:WP_034183546	methenyltetrahydrofolate cyclohydrolase [Burkholderia pyrrocinia].	48.25	286	137	3	1	286	1	275	4e-78	251
rs:WP_038806273	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus dentisani].	47.08	291	144	3	3	293	2	282	4e-78	251
tr:A3A2J6_ORYSJ	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EAZ21535.1};	47.08	291	148	2	3	291	80	366	4e-78	254
rs:WP_027361154	methenyltetrahydrofolate cyclohydrolase [Desulfovibrio acrylicus].	45.92	294	157	2	1	293	1	293	4e-78	251
rs:WP_029476500	methenyltetrahydrofolate cyclohydrolase [Dehalococcoidia bacterium SCGC AB-539-J10].	45.36	291	158	1	1	291	1	290	4e-78	251
rs:WP_006654368	5,10-methylene-tetrahydrofolate dehydrogenase [Natrialba hulunbeirensis].	44.95	287	156	2	4	290	3	287	4e-78	251
rs:WP_016214972	FolD protein [Eubacterium sp. 14-2].	49.65	284	132	4	3	286	2	274	4e-78	251
rs:WP_005732971	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas amygdali].	48.11	291	143	3	1	291	1	283	4e-78	251
tr:G3MHQ0_9ACAR	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:AEO33018.1}; Flags: Fragment;	45.70	291	155	2	5	293	37	326	4e-78	252
rs:WP_000192084	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	47.59	290	142	3	4	293	3	282	4e-78	251
sp:FOLD_PEDPA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.10	293	142	5	3	293	2	283	4e-78	251
rs:XP_009793634	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X1 [Nicotiana sylvestris].	45.42	295	155	2	2	294	61	351	4e-78	253
tr:A0A0E0G0A4_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA02G01460.1};	47.08	291	148	2	3	291	80	366	4e-78	254
rs:WP_007222822	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Jettenia caeni].	46.46	297	152	2	1	290	1	297	4e-78	251
rs:XP_010419612	PREDICTED: bifunctional protein FolD 4, chloroplastic-like [Camelina sativa].	45.70	291	152	2	3	291	56	342	4e-78	253
sp:FOLD1_GEOSL	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.74	291	147	4	5	293	3	287	4e-78	251
rs:WP_015458382	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas sp. MM-1].	48.29	292	144	3	1	291	1	286	4e-78	251
rs:WP_043092093	methenyltetrahydrofolate cyclohydrolase [Xanthomonas sacchari].	48.30	294	140	3	1	292	10	293	5e-78	251
rs:WP_032115165	methenyltetrahydrofolate cyclohydrolase [Arsenophonus endosymbiont of Nilaparvata lugens].	45.70	291	148	2	1	291	1	281	5e-78	251
rs:WP_022307441	bifunctional protein FolD [Alistipes sp. CAG:268].	49.29	282	134	3	5	286	2	274	5e-78	251
rs:WP_022728536	5,10-methylene-tetrahydrofolate dehydrogenase [Fodinicurvata sediminis].	47.24	290	147	2	3	292	4	287	5e-78	251
rs:WP_016424730	FolD protein [Staphylococcus sp. HGB0015].	46.39	291	143	5	1	290	1	279	5e-78	251
rs:WP_037512721	methenyltetrahydrofolate cyclohydrolase [Sphingopyxis sp. LC81].	46.21	290	152	1	2	291	3	288	5e-78	251
rs:WP_043301866	methenyltetrahydrofolate cyclohydrolase [Pseudomonas taeanensis].	47.59	290	146	2	2	291	3	286	5e-78	251
rs:WP_034156974	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. ERG5].	49.83	291	135	2	1	291	1	280	5e-78	251
rs:WP_008936550	MULTISPECIES: bifunctional protein FolD [Brucella].	48.64	294	143	4	3	292	2	291	5e-78	251
rs:XP_009793636	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X2 [Nicotiana sylvestris].	45.55	292	153	2	5	294	3	290	5e-78	251
rs:WP_036360893	methenyltetrahydrofolate cyclohydrolase [Microvirga lupini].	47.24	290	147	3	1	289	1	285	5e-78	251
rs:WP_005409307	methenyltetrahydrofolate cyclohydrolase [Stenotrophomonas maltophilia].	48.29	292	139	4	1	290	8	289	5e-78	251
rs:WP_004085960	methenyltetrahydrofolate cyclohydrolase [Xylella fastidiosa].	47.95	292	140	3	3	292	8	289	5e-78	251
rs:WP_003367102	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	47.62	294	146	3	1	294	1	286	5e-78	251
rs:WP_024960111	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.62	294	146	3	1	294	1	286	5e-78	251
rs:WP_013089832	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia sp. CCGE1002].	48.95	286	135	3	1	286	1	275	5e-78	251
rs:WP_014036908	methenyltetrahydrofolate cyclohydrolase [Stenotrophomonas maltophilia].	48.29	292	139	4	1	290	8	289	5e-78	251
tr:M7YLJ3_TRIUA	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:EMS48177.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:TRIUR3_06311-P1};	47.26	292	148	2	2	291	15	302	5e-78	251
tr:I1NWN9_ORYGL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORGLA02G0014500.1};	47.08	291	148	2	3	291	82	368	5e-78	253
tr:I2GLZ2_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.91	271	152	0	4	274	23	293	5e-78	251
rs:WP_024958549	methenyltetrahydrofolate cyclohydrolase [Stenotrophomonas maltophilia].	48.62	290	137	4	3	290	10	289	5e-78	251
rs:WP_017908092	methenyltetrahydrofolate cyclohydrolase [Xanthomonas sp. SHU199].	48.30	294	140	3	1	292	10	293	5e-78	251
rs:NP_001045713	Os02g0120900 [Oryza sativa Japonica Group].	47.08	291	148	2	3	291	80	366	5e-78	253
rs:WP_016407198	bifunctional protein FolD [Firmicutes bacterium CAG:102].	49.66	290	135	4	1	290	1	279	5e-78	251
rs:WP_029866244	methenyltetrahydrofolate cyclohydrolase [Pseudomonas taeanensis].	47.77	291	146	3	1	291	1	285	5e-78	251
rs:WP_002553896	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas savastanoi].	48.45	291	142	3	1	291	1	283	5e-78	251
rs:WP_027973041	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus porci].	46.76	293	146	2	3	295	2	284	5e-78	251
rs:WP_017917283	methenyltetrahydrofolate cyclohydrolase [Xanthomonas sp. SHU308].	48.30	294	140	3	1	292	10	293	5e-78	251
rs:WP_014621350	tetrahydrofolate dehydrogenase [Streptococcus thermophilus].	48.80	291	139	3	3	293	2	282	5e-78	251
rs:WP_009059022	5,10-methylene-tetrahydrofolate dehydrogenase [Methylacidiphilum fumariolicum].	45.73	293	157	2	3	294	4	295	5e-78	251
tr:M0XVL7_HORVD	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:MLOC_63447.1};	47.26	292	148	2	2	291	28	315	5e-78	252
sp:FOLD_BURM7	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.65	286	133	4	1	286	1	275	5e-78	251
rs:WP_017175773	MULTISPECIES: tetrahydrofolate dehydrogenase [Staphylococcus].	47.77	291	139	5	1	290	1	279	5e-78	251
rs:WP_000057234	tetrahydrofolate dehydrogenase [Streptococcus oralis].	47.08	291	144	3	3	293	2	282	5e-78	251
rs:XP_005715254	Methylenetetrahydrofolate dehydrogenase [Chondrus crispus].	46.42	293	148	4	6	293	1	289	5e-78	251
rs:WP_042901162	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	47.24	290	143	3	4	293	3	282	5e-78	251
rs:WP_031399482	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Burkholderia].	49.30	286	134	4	1	286	1	275	5e-78	251
sp:FOLD2_PSE14	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.77	291	144	3	1	291	1	283	5e-78	251
rs:WP_027198131	methenyltetrahydrofolate cyclohydrolase [Burkholderia sprentiae].	48.95	286	135	3	1	286	1	275	5e-78	251
rs:WP_017913744	methenyltetrahydrofolate cyclohydrolase [Xanthomonas sp. SHU166].	48.30	294	140	3	1	292	10	293	5e-78	251
rs:NP_001295406	bifunctional protein FolD 4, chloroplastic [Zea mays].	46.74	291	149	2	3	291	78	364	5e-78	253
tr:M5DJT7_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.10	293	132	4	6	292	1	276	5e-78	250
rs:WP_006361873	5,10-methylene-tetrahydrofolate dehydrogenase [Stenotrophomonas maltophilia].	48.29	292	139	4	1	290	8	289	5e-78	251
rs:WP_045804834	methenyltetrahydrofolate cyclohydrolase [Ehrlichia muris].	47.42	291	145	4	4	293	3	286	5e-78	251
sp:FOLD_VEREI	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.52	292	151	3	1	292	1	281	5e-78	251
tr:A0A0E0CE13_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI02G00920.1};	47.08	291	148	2	3	291	79	365	5e-78	253
tr:A0A099Q1H0_9XANT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.61	288	136	3	4	289	13	290	5e-78	251
rs:WP_037549286	bifunctional protein FolD [Staphylococcus haemolyticus].	45.86	290	146	3	1	290	1	279	6e-78	250
rs:WP_000192087	bifunctional protein FolD [Streptococcus pseudopneumoniae].	47.24	290	143	3	4	293	3	282	6e-78	250
rs:XP_005092550	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like isoform X1 [Aplysia californica].	45.97	298	153	3	2	293	47	342	6e-78	253
rs:WP_000057229	MULTISPECIES: tetrahydrofolate dehydrogenase [Streptococcus].	47.42	291	143	3	3	293	2	282	6e-78	250
rs:WP_034458628	methenyltetrahydrofolate cyclohydrolase [Bartonella koehlerae].	47.28	294	143	5	4	291	3	290	6e-78	251
rs:WP_041500189	methenyltetrahydrofolate cyclohydrolase [Xanthomonas sacchari].	48.30	294	140	3	1	292	10	293	6e-78	251
rs:WP_013797011	5,10-methylene-tetrahydrofolate dehydrogenase [Marinomonas posidonica].	47.75	289	144	2	5	293	4	285	6e-78	251
gpu:CP010999_576	Methenyltetrahydrofolate cyclohydrolase [Streptococcus thermophilus]	48.61	288	138	3	6	293	1	278	6e-78	250
rs:WP_044021072	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus sp. VT 162].	47.42	291	143	3	3	293	2	282	6e-78	250
rs:WP_031363878	methenyltetrahydrofolate cyclohydrolase [Burkholderia sordidicola].	46.42	293	146	4	1	293	1	282	6e-78	251
rs:WP_037521445	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. YL-JM2C].	48.62	290	144	2	2	291	3	287	6e-78	251
rs:WP_008298240	bifunctional protein FolD [Bhargavaea cecembensis].	47.10	293	144	3	1	293	1	282	6e-78	250
rs:WP_034565332	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter bilis].	45.30	287	146	4	5	291	8	283	6e-78	250
rs:WP_009729958	FolD protein [Streptococcus sp. F0441].	47.42	291	143	3	3	293	2	282	6e-78	250
rs:WP_028216863	methenyltetrahydrofolate cyclohydrolase [Burkholderia oxyphila].	47.26	292	143	3	1	292	1	281	6e-78	250
sp:FOLD_STRT1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.45	291	140	3	3	293	2	282	6e-78	250
rs:WP_047125280	methenyltetrahydrofolate cyclohydrolase [Xanthomonas arboricola].	48.44	289	137	3	3	289	12	290	6e-78	251
rs:WP_044679388	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.40	289	142	3	5	293	3	281	6e-78	250
rs:WP_004329856	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Alistipes].	48.79	289	139	3	5	293	2	281	6e-78	250
rs:XP_004629300	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Octodon degus].	46.64	298	152	3	3	294	20	316	7e-78	251
tr:F9HCH2_STRMT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.24	290	143	3	4	293	24	303	7e-78	251
tr:A0A0D9VBG8_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:LPERR02G01350.1};	46.74	291	149	2	3	291	79	365	7e-78	253
tr:W5GQQ2_WHEAT	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Traes_6BS_61205C056.1};	47.26	292	148	2	2	291	15	302	7e-78	251
tr:A0A0D3BAX5_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo3g064870.1};	45.58	294	154	2	2	293	9	298	7e-78	251
rs:WP_032448390	methenyltetrahydrofolate cyclohydrolase, partial [Brucella suis].	48.64	294	143	4	3	292	2	291	7e-78	251
rs:WP_024409758	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	7e-78	250
rs:WP_034926886	methenyltetrahydrofolate cyclohydrolase [Candidatus Accumulibacter sp. SK-01].	46.94	294	146	2	1	294	1	284	7e-78	250
rs:WP_002343033	FolD protein [Enterococcus faecium].	47.22	288	141	3	3	290	2	278	7e-78	250
rs:WP_019183081	methenyltetrahydrofolate cyclohydrolase [Stenotrophomonas maltophilia].	48.80	291	137	4	2	290	11	291	7e-78	251
rs:WP_007405232	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas].	46.90	290	143	3	2	291	3	281	7e-78	250
rs:WP_020815059	5,10-methylene-tetrahydrofolate dehydrogenase [[Clostridium] papyrosolvens].	47.40	289	141	3	1	289	1	278	7e-78	250
rs:XP_004494360	PREDICTED: bifunctional protein FolD 2 [Cicer arietinum].	44.37	293	157	2	3	293	2	290	7e-78	251
rs:WP_000057222	tetrahydrofolate dehydrogenase [Streptococcus mitis].	47.42	291	143	3	3	293	2	282	7e-78	250
rs:WP_000192088	tetrahydrofolate dehydrogenase [Streptococcus mitis].	47.24	290	143	3	4	293	3	282	7e-78	250
rs:WP_004625889	5,10-methylene-tetrahydrofolate dehydrogenase [[Clostridium] termitidis].	48.26	288	138	3	1	288	1	277	7e-78	250
rs:WP_005219016	5,10-methylene-tetrahydrofolate dehydrogenase [Helicobacter bilis].	44.95	287	147	4	5	291	8	283	7e-78	250
tr:A0A0B6YBK5_9EUPU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CEK53539.1};	47.62	294	146	3	6	293	90	381	7e-78	254
rs:WP_041379702	methenyltetrahydrofolate cyclohydrolase [Sphingomonas wittichii].	48.62	290	144	2	2	291	3	287	7e-78	251
rs:WP_000057235	MULTISPECIES: tetrahydrofolate dehydrogenase [Streptococcus].	47.42	291	143	3	3	293	2	282	7e-78	250
rs:WP_005992303	methenyltetrahydrofolate cyclohydrolase [Xanthomonas vesicatoria].	48.96	288	135	3	4	289	13	290	7e-78	250
rs:WP_010105035	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia oklahomensis].	48.95	286	135	4	1	286	1	275	7e-78	250
rs:WP_000057225	tetrahydrofolate dehydrogenase [Streptococcus oralis].	47.42	291	143	3	3	293	2	282	7e-78	250
rs:WP_046418197	methenyltetrahydrofolate cyclohydrolase [Xylella fastidiosa].	47.95	292	140	3	3	292	8	289	7e-78	250
rs:WP_009441366	tetrahydrofolate dehydrogenase [Selenomonas sp. oral taxon 138].	47.54	284	136	4	3	284	2	274	8e-78	250
rs:WP_024405613	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	8e-78	250
rs:WP_000192098	tetrahydrofolate dehydrogenase [Streptococcus sp. SK140].	47.24	290	143	3	4	293	3	282	8e-78	250
rs:WP_013567069	5,10-methylene-tetrahydrofolate dehydrogenase [Terriglobus saanensis].	43.58	296	145	4	5	284	2	291	8e-78	251
rs:WP_014637572	tetrahydrofolate dehydrogenase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	8e-78	250
rs:WP_033686684	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	47.24	290	143	3	4	293	3	282	8e-78	250
rs:WP_007520343	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus tigurinus].	47.08	291	144	3	3	293	2	282	8e-78	250
rs:WP_019661315	methenyltetrahydrofolate cyclohydrolase [Stenotrophomonas maltophilia].	48.29	292	139	3	3	292	10	291	8e-78	250
rs:WP_010436658	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	47.28	294	147	3	1	294	1	286	8e-78	251
rs:WP_000057224	MULTISPECIES: tetrahydrofolate dehydrogenase [Streptococcus].	47.42	291	143	3	3	293	2	282	8e-78	250
rs:WP_016567939	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	47.62	294	146	3	1	294	1	286	8e-78	251
rs:WP_017176610	tetrahydrofolate dehydrogenase [Staphylococcus massiliensis].	46.21	290	145	3	1	290	1	279	8e-78	250
rs:WP_024406969	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	8e-78	250
rs:WP_008267526	methenyltetrahydrofolate cyclohydrolase [Stenotrophomonas sp. SKA14].	47.95	292	140	4	1	290	8	289	8e-78	250
tr:F2HZ57_BRUMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.64	294	143	4	3	292	16	305	8e-78	251
rs:WP_038764810	methenyltetrahydrofolate cyclohydrolase [Burkholderia pseudomallei].	49.30	286	134	4	1	286	1	275	8e-78	250
rs:WP_038723185	methenyltetrahydrofolate cyclohydrolase [Burkholderia pseudomallei].	49.30	286	134	4	1	286	1	275	8e-78	250
tr:A0A077VQ14_STAAU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.83	290	149	3	1	290	1	279	8e-78	250
rs:XP_001765412	predicted protein [Physcomitrella patens].	44.67	291	155	2	5	293	16	302	8e-78	251
rs:XP_010734279	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Larimichthys crocea].	47.16	299	151	3	2	294	212	509	8e-78	257
rs:XP_010734279	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Larimichthys crocea].	40.98	183	102	2	2	182	50	228	5e-32	134
rs:WP_038733041	methenyltetrahydrofolate cyclohydrolase, partial [Burkholderia pseudomallei].	52.12	259	113	4	28	286	7	254	8e-78	249
rs:WP_004533926	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia pseudomallei].	49.30	286	134	4	1	286	1	275	9e-78	250
rs:WP_043950197	methenyltetrahydrofolate cyclohydrolase [Candidatus Phaeomarinobacter ectocarpi].	46.42	293	152	2	1	292	1	289	9e-78	250
rs:XP_001702917	5,10-methylenetetrahydrofolate dehydrogenase [Chlamydomonas reinhardtii].	45.05	293	155	2	2	292	44	332	9e-78	252
tr:M8CRU7_AEGTA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:EMT26406.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:EMT26406};	47.26	292	148	2	2	291	21	308	9e-78	251
gp:CP000024_588	methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase [Streptococcus thermophilus CNRZ1066]	48.45	291	140	3	3	293	6	286	9e-78	250
rs:WP_033475538	methenyltetrahydrofolate cyclohydrolase, partial [Xanthomonas axonopodis].	48.26	288	137	3	4	289	13	290	9e-78	250
rs:WP_016465575	FolD protein [Streptococcus sp. HPH0090].	47.59	290	142	3	4	293	3	282	9e-78	250
rs:WP_002315414	tetrahydrofolate dehydrogenase [Enterococcus faecium].	47.22	288	141	3	3	290	2	278	9e-78	250
tr:A9NV85_PICSI	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:ABK24546.1};	46.23	292	151	2	3	292	102	389	9e-78	253
rs:WP_010723824	FolD protein [Enterococcus faecium].	46.88	288	142	3	3	290	2	278	9e-78	250
rs:WP_023396215	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	46.90	290	144	3	4	293	3	282	9e-78	250
rs:WP_014616908	5,10-methylene-tetrahydrofolate dehydrogenase [Ralstonia solanacearum].	46.85	286	141	3	1	286	1	275	9e-78	250
rs:WP_002639783	5,10-methylene-tetrahydrofolate dehydrogenase [Myxococcus sp. (contaminant ex DSM 436)].	47.08	291	143	3	3	293	2	281	9e-78	250
gp:CP000542_1882	Methenyltetrahydrofolate cyclohydrolase [Verminephrobacter eiseniae EF01-2]	44.52	292	151	3	1	292	15	295	9e-78	250
sp:FOLD1_ARATH	RecName: Full=Bifunctional protein FolD 1, mitochondrial; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Flags: Precursor;	46.02	289	150	2	5	291	65	349	9e-78	252
rs:WP_000057232	tetrahydrofolate dehydrogenase [Streptococcus oralis].	47.08	291	144	3	3	293	2	282	9e-78	250
gpu:CP011503_113	methenyltetrahydrofolate cyclohydrolase [Burkholderia pyrrocinia]	48.25	286	137	3	1	286	1	275	1e-77	250
sp:FOLD3_SPHWW	RecName: Full=Bifunctional protein FolD 3 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.62	290	144	2	2	291	8	292	1e-77	251
sp:FOLD_BRUA1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.64	294	143	4	3	292	2	291	1e-77	250
tr:D0P7A2_BRUSS	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.64	294	143	4	3	292	2	291	1e-77	251
rs:WP_005878108	5,10-methylene-tetrahydrofolate dehydrogenase [Oxalobacter formigenes].	47.78	293	142	4	1	293	1	282	1e-77	250
rs:WP_042822495	methenyltetrahydrofolate cyclohydrolase [Xanthomonas axonopodis].	48.26	288	137	3	4	289	13	290	1e-77	250
gp:HB883459_1	Sequence 16134 from Patent EP2096177. [Arabidopsis thaliana]	46.02	289	150	2	5	291	63	347	1e-77	252
rs:WP_042739870	methenyltetrahydrofolate cyclohydrolase [Staphylococcus gallinarum].	45.17	290	148	3	1	290	1	279	1e-77	250
rs:XP_008334318	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Cynoglossus semilaevis].	47.16	299	151	3	2	294	50	347	1e-77	252
rs:WP_017171176	methenyltetrahydrofolate cyclohydrolase [Xanthomonas axonopodis].	48.26	288	137	3	4	289	13	290	1e-77	250
rs:WP_034346028	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter trogontum].	44.25	287	149	3	5	291	3	278	1e-77	249
rs:WP_000057219	tetrahydrofolate dehydrogenase [Streptococcus sp. C300].	47.08	291	144	3	3	293	2	282	1e-77	250
rs:WP_027875699	methenyltetrahydrofolate cyclohydrolase [Mesoplasma chauliocola].	45.33	289	149	3	5	293	3	282	1e-77	250
rs:WP_009938160	FolD bifunctional protein, partial [Burkholderia pseudomallei].	52.12	259	113	4	28	286	3	250	1e-77	249
rs:WP_005413112	methylenetetrahydrofolate dehydrogenase [Stenotrophomonas maltophilia].	48.62	290	137	4	3	290	10	289	1e-77	250
rs:WP_006827975	5,10-methylene-tetrahydrofolate dehydrogenase [Natrialba taiwanensis].	44.33	300	152	3	4	289	3	301	1e-77	251
rs:WP_031236893	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	46.90	290	144	3	4	293	3	282	1e-77	250
rs:WP_024939210	methenyltetrahydrofolate cyclohydrolase [Xanthomonas arboricola].	48.26	288	137	3	4	289	13	290	1e-77	250
tr:C4IV71_BRUAO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.64	294	143	4	3	292	22	311	1e-77	251
rs:WP_044761897	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.40	289	142	3	5	293	3	281	1e-77	249
sp:FOLD_WOLTR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.50	286	145	3	5	289	4	282	1e-77	250
tr:H3DEH6_TETNG	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTNIP00000018919};	47.67	300	149	4	3	295	30	328	1e-77	251
sp:FOLD_STRPN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.90	290	144	3	4	293	3	282	1e-77	249
rs:WP_006516934	5,10-methylene-tetrahydrofolate dehydrogenase [Leptolyngbya sp. PCC 7375].	46.37	289	150	2	3	291	2	285	1e-77	250
rs:WP_040228702	5,10-methylene-tetrahydrofolate cyclohydrolase [Bhargavaea cecembensis].	45.73	293	148	3	1	293	1	282	1e-77	250
rs:WP_045617432	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	47.42	291	143	3	3	293	2	282	1e-77	249
rs:WP_029766964	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. P818].	48.45	291	142	3	1	291	1	283	1e-77	250
rs:WP_022152506	bifunctional protein FolD [Lachnospiraceae bacterium CAG:215].	49.48	287	134	4	5	291	4	279	1e-77	249
rs:WP_046342929	methenyltetrahydrofolate cyclohydrolase [Xanthomonas campestris].	48.26	288	137	3	4	289	13	290	1e-77	250
tr:W5GFV6_WHEAT	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Traes_6AS_BAB9A28AB.2};	46.92	292	149	2	2	291	21	308	1e-77	251
rs:WP_005416247	5,10-methylene-tetrahydrofolate dehydrogenase [Stenotrophomonas maltophilia].	48.62	290	137	4	3	290	10	289	1e-77	250
rs:WP_017157588	methenyltetrahydrofolate cyclohydrolase [Xanthomonas axonopodis].	48.26	288	137	3	4	289	13	290	1e-77	250
rs:WP_015019725	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Nitrososphaera gargensis].	47.28	294	141	4	1	292	1	282	1e-77	249
rs:WP_020001390	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfovibrio desulfuricans].	45.92	294	157	2	1	293	1	293	1e-77	250
rs:WP_021838252	bifunctional protein FolD [Alistipes sp. CAG:514].	47.81	297	136	5	5	292	2	288	1e-77	249
rs:WP_044775365	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	1e-77	249
rs:WP_000192092	tetrahydrofolate dehydrogenase [Streptococcus sp. oral taxon 071].	47.24	290	143	3	4	293	3	282	1e-77	249
rs:WP_014965465	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Nitrosopumilus].	47.40	289	138	4	6	292	6	282	1e-77	249
rs:WP_009783783	methenyltetrahydrofolate cyclohydrolase [Lyngbya sp. PCC 8106].	47.77	291	146	2	3	293	2	286	1e-77	250
rs:WP_012479956	methenyltetrahydrofolate cyclohydrolase [Stenotrophomonas maltophilia].	48.62	290	137	4	3	290	10	289	1e-77	250
rs:WP_009656400	5,10-methylene-tetrahydrofolate dehydrogenase [Selenomonas sp. FOBRC6].	47.54	284	136	4	3	284	2	274	1e-77	249
rs:WP_045727540	methenyltetrahydrofolate cyclohydrolase [Xanthomonas sp. GPE 39].	46.96	296	145	3	1	294	10	295	1e-77	250
rs:WP_020875229	hypothetical protein [Desulfococcus multivorans].	47.47	297	149	2	1	290	1	297	1e-77	250
rs:XP_005167203	PREDICTED: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like isoform X1 [Danio rerio].	44.59	296	157	3	3	292	51	345	1e-77	251
rs:WP_024532457	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.39	287	141	3	6	292	4	280	1e-77	249
rs:WP_037505997	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. DC-6].	48.62	290	144	2	2	291	3	287	1e-77	250
rs:WP_034912064	methenyltetrahydrofolate cyclohydrolase [Gilliamella apicola].	47.42	291	142	3	1	291	1	280	1e-77	249
rs:WP_004253833	tetrahydrofolate dehydrogenase [Streptococcus mitis].	46.90	290	144	3	4	293	3	282	1e-77	249
rs:WP_033584982	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus sp. SR1].	47.42	291	143	3	3	293	2	282	1e-77	249
rs:WP_029188701	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	1e-77	249
rs:WP_029174040	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	1e-77	249
rs:WP_015646548	methylenetetrahydrofolate dehydrogenase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	1e-77	249
rs:XP_006294495	hypothetical protein CARUB_v10023524mg [Capsella rubella].	46.02	289	150	2	5	291	65	349	1e-77	252
tr:F2D8I9_HORVD	SubName: Full=Predicted protein {ECO:0000313|EMBL:BAJ91410.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:MLOC_14916.1};	45.05	293	155	2	3	293	2	290	1e-77	249
rs:WP_000192080	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	46.90	290	144	3	4	293	3	282	1e-77	249
rs:WP_006153575	tetrahydrofolate dehydrogenase [Streptococcus infantis].	46.55	290	145	3	4	293	3	282	1e-77	249
rs:WP_035969217	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. WSM1417].	47.40	289	146	2	1	289	1	283	1e-77	251
rs:WP_000192091	tetrahydrofolate dehydrogenase [Streptococcus mitis].	47.24	290	143	3	4	293	3	282	1e-77	249
rs:WP_037614694	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus sinensis].	46.37	289	145	3	5	293	4	282	1e-77	249
rs:WP_024380045	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	1e-77	249
rs:WP_006755473	bifunctional protein FolD [Burkholderia ambifaria].	48.25	286	137	3	1	286	1	275	1e-77	249
rs:WP_026216878	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus merionis].	47.89	284	138	2	5	288	3	276	1e-77	249
rs:XP_006654056	PREDICTED: bifunctional protein FolD 2-like [Oryza brachyantha].	46.42	293	151	2	3	293	2	290	1e-77	249
rs:WP_007969695	methenyltetrahydrofolate cyclohydrolase [Xanthomonas fuscans].	47.92	288	138	3	4	289	13	290	1e-77	250
rs:WP_006628116	5,10-methylene-tetrahydrofolate dehydrogenase [Halorubrum tebenquichense].	50.17	287	139	4	4	289	3	286	1e-77	250
tr:A0A093Q1Q9_9PASS	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFW82938.1}; Flags: Fragment;	50.18	277	130	4	22	291	1	276	1e-77	249
rs:WP_000057230	MULTISPECIES: tetrahydrofolate dehydrogenase [Streptococcus].	47.42	291	143	3	3	293	2	282	2e-77	249
rs:WP_044753633	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	2e-77	249
rs:WP_039001496	methenyltetrahydrofolate cyclohydrolase [Halocynthiibacter sp. PAMC 20958].	47.44	293	149	2	1	292	1	289	2e-77	250
rs:WP_000192081	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	46.90	290	144	3	4	293	3	282	2e-77	249
rs:WP_009383681	5,10-methylene-tetrahydrofolate dehydrogenase [Staphylococcus massiliensis].	46.21	290	145	3	1	290	1	279	2e-77	249
rs:WP_029348465	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium ciceri].	48.14	295	137	5	3	289	2	288	2e-77	250
rs:WP_014868843	5,10-methylene-tetrahydrofolate dehydrogenase [Wolbachia endosymbiont of Onchocerca ochengi].	46.32	285	145	3	5	288	4	281	2e-77	250
rs:XP_010038191	PREDICTED: bifunctional protein FolD 2 [Eucalyptus grandis].	45.39	293	154	2	3	293	11	299	2e-77	250
tr:X8HI28_9STRE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.42	291	143	3	3	293	9	289	2e-77	249
rs:WP_032136050	hypothetical protein [Alistipes sp. AL-1].	46.81	282	141	3	5	286	2	274	2e-77	249
rs:WP_004195719	tetrahydrofolate dehydrogenase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	2e-77	249
rs:WP_008877464	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium metallidurans].	48.47	295	136	5	3	289	2	288	2e-77	250
rs:WP_012916083	methenyltetrahydrofolate cyclohydrolase [Xanthomonas albilineans].	47.12	295	144	3	1	293	10	294	2e-77	249
tr:G5BU08_HETGA	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:EHB12766.1}; Flags: Fragment;	47.32	298	150	3	3	294	4	300	2e-77	250
rs:WP_031658786	bifunctional protein FolD [Listeria monocytogenes].	49.48	289	135	4	3	291	2	279	2e-77	249
rs:WP_009271774	5,10-methylene-tetrahydrofolate dehydrogenase [Erysipelotrichaceae bacterium 3_1_53].	46.58	292	142	4	5	294	4	283	2e-77	249
rs:WP_042332249	methenyltetrahydrofolate cyclohydrolase [Candidatus Accumulibacter sp. BA-92].	47.62	294	143	3	1	294	1	283	2e-77	249
rs:WP_025264343	methenyltetrahydrofolate cyclohydrolase [Wolbachia endosymbiont of Onchocerca volvulus].	46.32	285	145	3	5	288	4	281	2e-77	249
rs:WP_043026222	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	2e-77	249
rs:WP_010507043	methenyltetrahydrofolate cyclohydrolase [gamma proteobacterium SCGC AAA001-B15].	46.71	289	140	4	5	293	3	277	2e-77	249
rs:WP_032087758	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus aquimaris].	44.14	290	151	4	1	290	1	279	2e-77	249
rs:WP_039434798	methenyltetrahydrofolate cyclohydrolase [Xanthomonas vasicola].	47.92	288	138	3	4	289	13	290	2e-77	250
rs:WP_005851661	5,10-methylene-tetrahydrofolate dehydrogenase [Sulfitobacter sp. EE-36].	49.49	293	143	2	1	292	1	289	2e-77	249
rs:XP_004900117	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Heterocephalus glaber].	47.32	298	150	3	3	294	22	318	2e-77	250
rs:WP_003267677	5,10-methylene-tetrahydrofolate dehydrogenase [Ralstonia solanacearum].	46.85	286	141	3	1	286	1	275	2e-77	249
rs:XP_010509156	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X1 [Camelina sativa].	46.37	289	149	2	5	291	66	350	2e-77	251
rs:WP_024849130	methenyltetrahydrofolate cyclohydrolase [Aminobacter sp. J41].	49.48	291	138	5	3	289	2	287	2e-77	249
rs:WP_002938697	tetrahydrofolate dehydrogenase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	2e-77	249
rs:WP_035518004	methenyltetrahydrofolate cyclohydrolase [Burkholderia sp. Ch1-1].	48.95	286	135	4	1	286	1	275	2e-77	249
rs:WP_029572448	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.28	294	147	3	1	294	1	286	2e-77	249
rs:WP_024378968	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	2e-77	249
rs:WP_000192102	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	46.90	290	144	3	4	293	3	282	2e-77	249
tr:V8IE99_STRMT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.90	290	144	3	4	293	14	293	2e-77	249
rs:WP_029455868	methenyltetrahydrofolate cyclohydrolase [Candidatus Pelagibacter ubique].	46.18	288	144	3	5	292	3	279	2e-77	249
rs:WP_026387558	methenyltetrahydrofolate cyclohydrolase [Acidobacteria bacterium KBS 146].	43.05	302	150	4	5	290	7	302	2e-77	250
tr:F2QED9_STROU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.42	291	143	3	3	293	9	289	2e-77	249
rs:WP_000057233	tetrahydrofolate dehydrogenase [Streptococcus oralis].	47.42	291	143	3	3	293	2	282	2e-77	249
rs:WP_044774799	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.06	289	143	3	5	293	3	281	2e-77	249
rs:WP_024414782	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	2e-77	249
sp:FOLD_NOVAD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.89	292	153	2	1	292	1	287	2e-77	249
rs:WP_046533230	methenyltetrahydrofolate cyclohydrolase [Candidatus Accumulibacter phosphatis].	48.14	295	140	5	1	294	1	283	2e-77	249
tr:J2QMY4_9PSED	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.79	289	139	3	3	290	15	295	2e-77	250
rs:WP_044764556	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	2e-77	249
rs:WP_037535266	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. RIT328].	46.39	291	145	3	1	291	1	280	2e-77	249
rs:WP_045611387	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	46.90	290	144	3	4	293	3	282	2e-77	249
rs:WP_046100338	methenyltetrahydrofolate cyclohydrolase [Staphylococcus carnosus].	45.17	290	148	3	1	290	1	279	2e-77	249
rs:WP_010764025	FolD protein [Enterococcus moraviensis].	48.28	290	139	4	3	292	2	280	2e-77	249
tr:W7WK28_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.37	270	123	4	23	292	1	259	2e-77	248
rs:WP_007249725	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae group genomosp. 3].	47.28	294	147	3	1	294	1	286	2e-77	249
rs:WP_000192089	bifunctional protein FolD [Streptococcus mitis].	46.90	290	144	3	4	293	3	282	2e-77	249
rs:WP_044753176	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.22	288	142	3	5	292	3	280	2e-77	249
rs:WP_000057227	tetrahydrofolate dehydrogenase [Streptococcus oralis].	47.08	291	144	3	3	293	2	282	2e-77	249
rs:XP_010505509	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X1 [Camelina sativa].	46.37	289	149	2	5	291	65	349	2e-77	251
tr:B2DXP5_STREE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.90	290	144	3	4	293	10	289	2e-77	249
sp:FOLD3_PSEMY	RecName: Full=Bifunctional protein FolD 3 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	50.00	288	134	6	4	290	8	286	2e-77	250
rs:WP_029179913	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	2e-77	249
rs:WP_004418072	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	47.28	294	147	3	1	294	1	286	2e-77	249
rs:WP_000192113	tetrahydrofolate dehydrogenase [Streptococcus sp. SK643].	47.24	290	143	3	4	293	3	282	2e-77	249
rs:WP_028639969	methenyltetrahydrofolate cyclohydrolase [Novosphingobium acidiphilum].	48.29	292	146	2	1	292	1	287	2e-77	249
rs:WP_045606219	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	47.24	290	143	3	4	293	3	282	2e-77	249
rs:WP_003747562	5,10-methylene-tetrahydrofolate dehydrogenase [Listeria seeligeri].	49.83	289	134	4	3	291	2	279	2e-77	249
tr:F9MHE3_STRMT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.24	290	143	3	4	293	24	303	2e-77	249
rs:XP_011082630	PREDICTED: bifunctional protein FolD 2 [Sesamum indicum].	45.73	293	153	2	3	293	159	447	2e-77	254
rs:WP_010317897	methenyltetrahydrofolate cyclohydrolase [Synechococcus sp. CB0205].	47.54	284	144	2	3	286	2	280	2e-77	249
rs:WP_000192111	tetrahydrofolate dehydrogenase [Streptococcus pseudopneumoniae].	46.90	290	144	3	4	293	3	282	2e-77	249
rs:WP_017331824	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia pyrrocinia].	48.25	286	137	3	1	286	1	275	2e-77	249
rs:WP_034876381	5,10-methylene-tetrahydrofolate cyclohydrolase [Enterococcus avium].	45.70	291	147	4	3	293	2	281	2e-77	249
rs:WP_006694802	5,10-methylene-tetrahydrofolate dehydrogenase [Selenomonas noxia].	47.24	290	140	4	3	290	2	280	2e-77	249
rs:WP_024385039	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	2e-77	249
tr:T1C0L2_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EQD75542.1};	47.75	289	140	2	1	289	1	278	2e-77	249
rs:XP_006648247	PREDICTED: bifunctional protein FolD 4, chloroplastic-like [Oryza brachyantha].	46.55	290	149	2	4	291	23	308	2e-77	250
rs:WP_020902241	tetrahydrofolate dehydrogenase [Streptococcus mitis].	46.90	290	144	3	4	293	3	282	2e-77	249
rs:WP_009522502	5,10-methylene-tetrahydrofolate dehydrogenase [Ralstonia sp. PBA].	47.60	292	142	4	1	292	1	281	2e-77	249
rs:WP_039521785	methenyltetrahydrofolate cyclohydrolase [Xanthomonas arboricola].	48.26	288	137	3	4	289	13	290	2e-77	249
rs:WP_034322927	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter trogontum].	43.90	287	150	3	5	291	3	278	2e-77	249
rs:WP_023927307	hypothetical protein [Helicobacter macacae].	44.04	302	137	5	5	288	3	290	2e-77	249
rs:WP_000192108	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	47.24	290	143	3	4	293	3	282	2e-77	249
rs:WP_000057228	tetrahydrofolate dehydrogenase [Streptococcus sp. M143].	46.74	291	145	3	3	293	2	282	2e-77	249
rs:WP_024409162	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	2e-77	249
rs:WP_032653851	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.62	294	146	3	1	294	1	286	2e-77	249
rs:WP_041960977	methenyltetrahydrofolate cyclohydrolase, partial [Bradyrhizobium japonicum].	48.10	289	144	2	1	289	1	283	2e-77	249
rs:WP_033681548	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	46.90	290	144	3	4	293	3	282	2e-77	249
tr:S0SA49_ENTAV	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.70	291	147	4	3	293	4	283	2e-77	249
rs:WP_039577510	methenyltetrahydrofolate cyclohydrolase [Sphingopyxis sp. Kp5.2].	46.21	290	152	1	2	291	3	288	2e-77	249
rs:WP_000192082	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	46.90	290	144	3	4	293	3	282	2e-77	249
sp:FOLD_CLOCE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.37	285	139	3	1	285	1	274	2e-77	249
rs:WP_047190119	methenyltetrahydrofolate cyclohydrolase [Microvirga vignae].	46.21	290	150	3	1	289	1	285	2e-77	249
rs:WP_002442099	tetrahydrofolate dehydrogenase [Staphylococcus caprae].	46.21	290	145	3	1	290	1	279	2e-77	249
rs:WP_034777984	5,10-methylene-tetrahydrofolate cyclohydrolase [Exiguobacterium mexicanum].	47.24	290	140	4	3	292	2	278	2e-77	249
rs:WP_023348495	hypothetical protein [Firmicutes bacterium ASF500].	46.05	291	143	3	1	291	1	277	3e-77	249
rs:WP_031965109	methenyltetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	49.48	289	135	5	4	290	12	291	3e-77	249
rs:WP_022107921	bifunctional protein FolD [Clostridium sp. CAG:138].	46.37	289	143	3	3	291	2	278	3e-77	249
rs:WP_033676807	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	46.90	290	144	3	4	293	3	282	3e-77	249
tr:I0T4W9_STRMT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.90	290	144	3	4	293	10	289	3e-77	249
tr:D6ZLY1_STRP0	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.90	290	144	3	4	293	24	303	3e-77	249
rs:WP_038468312	5,10-methylene-tetrahydrofolate cyclohydrolase [Mollicutes bacterium HR1].	45.42	284	144	2	3	286	2	274	3e-77	249
rs:WP_007963224	methenyltetrahydrofolate cyclohydrolase [Xanthomonas fuscans].	47.92	288	138	3	4	289	13	290	3e-77	249
rs:WP_029220051	methenyltetrahydrofolate cyclohydrolase [Xanthomonas cassavae].	48.26	288	137	3	4	289	13	290	3e-77	249
rs:WP_034805941	5,10-methylene-tetrahydrofolate cyclohydrolase [Exiguobacterium sp. AB2].	47.75	289	138	4	3	291	2	277	3e-77	248
rs:WP_037506009	methenyltetrahydrofolate cyclohydrolase [Sphingomonas wittichii].	48.28	290	145	2	2	291	3	287	3e-77	249
rs:XP_012194852	hypothetical protein SPRG_01237 [Saprolegnia parasitica CBS 223.65].	46.78	295	149	3	3	293	2	292	3e-77	249
rs:WP_000192110	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	46.90	290	144	3	4	293	3	282	3e-77	249
rs:WP_023369567	FolD bifunctional protein [Streptococcus suis].	47.57	288	141	3	5	292	3	280	3e-77	249
rs:WP_024663488	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.28	294	147	3	1	294	1	286	3e-77	249
rs:WP_024588460	methenyltetrahydrofolate cyclohydrolase [Aliihoeflea sp. 2WW].	48.98	294	142	4	3	292	2	291	3e-77	249
rs:WP_009826115	5,10-methylene-tetrahydrofolate dehydrogenase [Sulfitobacter sp. NAS-14.1].	49.49	293	143	2	1	292	1	289	3e-77	249
rs:WP_000057223	tetrahydrofolate dehydrogenase [Streptococcus oralis].	47.08	291	144	3	3	293	2	282	3e-77	249
rs:WP_019149637	5,10-methylene-tetrahydrofolate dehydrogenase [Alistipes senegalensis].	47.18	284	141	3	3	286	2	276	3e-77	249
rs:WP_002950215	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus thermophilus].	48.80	291	139	3	3	293	2	282	3e-77	249
tr:A0A022RT23_ERYGU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYU42065.1};	46.42	293	151	2	3	293	73	361	3e-77	251
rs:WP_000192107	tetrahydrofolate dehydrogenase [Streptococcus mitis].	46.90	290	144	3	4	293	3	282	3e-77	249
rs:WP_042589823	methenyltetrahydrofolate cyclohydrolase [Ralstonia solanacearum].	46.50	286	142	3	1	286	1	275	3e-77	249
rs:WP_022559245	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Xanthomonas].	47.92	288	138	3	4	289	13	290	3e-77	249
rs:WP_022843193	5,10-methylene-tetrahydrofolate dehydrogenase [Acidobacteriaceae bacterium TAA166].	43.23	303	150	4	4	290	6	302	3e-77	249
rs:WP_046444687	5,10-methylene-tetrahydrofolate cyclohydrolase [Catabacter hongkongensis].	44.83	290	149	2	1	290	1	279	3e-77	248
rs:WP_002339617	FolD protein [Enterococcus faecium].	46.88	288	142	3	3	290	2	278	3e-77	248
rs:WP_008510792	bifunctional protein FolD [Brucella inopinata].	48.30	294	144	4	3	292	2	291	3e-77	249
rs:WP_006634145	methenyltetrahydrofolate cyclohydrolase [Microcoleus vaginatus].	45.99	287	145	3	2	286	5	283	3e-77	249
rs:WP_019515525	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas sp. Mn802worker].	49.14	291	136	4	1	291	1	279	3e-77	249
rs:WP_034636194	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus manliponensis].	48.63	292	139	4	1	292	1	281	3e-77	249
rs:WP_008572374	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Xanthomonas].	47.92	288	138	3	4	289	13	290	3e-77	249
rs:WP_013516631	methenyltetrahydrofolate cyclohydrolase [Candidatus Blochmannia vafer].	45.14	288	148	2	1	288	1	278	3e-77	248
rs:WP_042300304	methenyltetrahydrofolate cyclohydrolase [Burkholderia kururiensis].	48.96	288	139	4	2	289	3	282	3e-77	249
rs:WP_039571166	methenyltetrahydrofolate cyclohydrolase [Xanthomonas axonopodis].	47.92	288	138	3	4	289	13	290	3e-77	249
rs:WP_034327189	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter].	46.15	286	143	4	5	290	3	277	3e-77	248
sp:FOLD_SYNJA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.15	286	148	2	1	286	1	280	3e-77	249
rs:WP_036158172	5,10-methylene-tetrahydrofolate cyclohydrolase [Lysinibacillus odysseyi].	46.76	293	145	4	1	293	1	282	3e-77	249
rs:WP_044323513	methenyltetrahydrofolate cyclohydrolase [Pseudomonas amygdali].	47.77	291	144	3	1	291	1	283	3e-77	249
sp:FOLD_XANC5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.92	288	138	3	4	289	13	290	3e-77	249
rs:WP_024665541	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.28	294	147	3	1	294	1	286	3e-77	249
rs:WP_014646864	methenyltetrahydrofolate cyclohydrolase [Stenotrophomonas maltophilia].	48.62	290	137	4	3	290	10	289	3e-77	249
rs:WP_022974273	methenyltetrahydrofolate cyclohydrolase [Xanthomonas sp. M97].	47.10	293	143	3	2	292	11	293	3e-77	249
rs:WP_027080391	methenyltetrahydrofolate cyclohydrolase [Luteimonas mephitis].	48.63	292	138	3	3	292	7	288	3e-77	249
tr:T0J1G7_9SPHN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.42	291	148	2	2	292	6	291	3e-77	249
tr:I1C4I7_RHIO9	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EIE83367.1};	47.64	296	145	4	2	291	4	295	4e-77	264
rs:WP_010263035	5,10-methylene-tetrahydrofolate dehydrogenase [Alistipes timonensis].	47.16	282	140	3	5	286	2	274	4e-77	248
rs:WP_031342059	methenyltetrahydrofolate cyclohydrolase [Novosphingobium lindaniclasticum].	47.42	291	148	2	2	292	3	288	4e-77	249
rs:WP_026637488	5,10-methylene-tetrahydrofolate cyclohydrolase [Duganella zoogloeoides].	46.58	292	145	4	1	292	1	281	4e-77	248
rs:WP_045590825	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	47.08	291	144	3	3	293	2	282	4e-77	248
rs:WP_029187359	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	4e-77	248
rs:WP_039515110	methenyltetrahydrofolate cyclohydrolase [Xanthomonas arboricola].	47.92	288	138	3	4	289	13	290	4e-77	249
rs:WP_015799918	bifunctional protein FolD [Brucella microti].	48.30	294	144	4	3	292	2	291	4e-77	249
rs:WP_006193516	bifunctional protein FolD [Brucella suis].	48.30	294	144	4	3	292	2	291	4e-77	249
rs:WP_027855977	methenyltetrahydrofolate cyclohydrolase [Marinobacterium jannaschii].	47.77	291	145	2	3	293	2	285	4e-77	249
rs:WP_025168721	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus peroris].	46.90	290	144	3	4	293	3	282	4e-77	248
tr:I0SPJ0_STRMT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.24	290	143	3	4	293	24	303	4e-77	249
rs:WP_038271427	methenyltetrahydrofolate cyclohydrolase [Xylella fastidiosa].	47.95	292	140	3	3	292	8	289	4e-77	248
rs:WP_020902948	tetrahydrofolate dehydrogenase [Streptococcus mitis].	46.90	290	144	3	4	293	3	282	4e-77	248
tr:G3A797_9RALS	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.55	286	139	3	1	286	1	275	4e-77	248
tr:R2VDV7_9ENTE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.70	291	147	4	3	293	4	283	4e-77	248
sp:FOLD_SPICI	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.94	283	143	2	4	286	5	277	4e-77	248
rs:WP_034818109	5,10-methylene-tetrahydrofolate cyclohydrolase [Exiguobacterium alkaliphilum].	47.75	289	138	4	3	291	2	277	4e-77	248
tr:L7MM44_9ACAR	SubName: Full=Putative c1-tetrahydrofolate synthase {ECO:0000313|EMBL:JAA64304.1}; Flags: Fragment;	44.56	294	160	2	2	293	63	355	4e-77	251
tr:E4U9L2_OCEP5	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576}; Flags: Precursor;	46.32	285	137	4	6	290	5	273	4e-77	248
rs:WP_044686901	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	4e-77	248
rs:WP_006152537	tetrahydrofolate dehydrogenase [Streptococcus infantis].	46.90	290	144	3	4	293	3	282	4e-77	248
rs:WP_044781490	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.22	288	142	3	5	292	3	280	4e-77	248
rs:WP_014735556	tetrahydrofolate dehydrogenase [Streptococcus suis].	47.22	288	142	3	5	292	3	280	4e-77	248
rs:WP_036050583	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Burkholderia].	47.42	291	142	4	2	292	3	282	4e-77	248
rs:WP_026867466	methenyltetrahydrofolate cyclohydrolase [Jeotgalicoccus marinus].	46.21	290	143	5	1	290	1	277	4e-77	248
rs:WP_044685945	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	4e-77	248
rs:WP_022417523	bifunctional protein FolD [Eubacterium sp. CAG:841].	46.55	290	144	3	3	292	2	280	4e-77	248
rs:WP_006175343	MULTISPECIES: bifunctional protein FolD [Brucella].	48.30	294	144	4	3	292	2	291	4e-77	249
rs:WP_035974743	methenyltetrahydrofolate cyclohydrolase, partial [Bradyrhizobium sp. WSM471].	47.06	289	147	2	1	289	1	283	4e-77	248
rs:WP_024418634	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.22	288	142	3	5	292	3	280	4e-77	248
rs:WP_041554128	methenyltetrahydrofolate cyclohydrolase [Oceanithermus profundus].	46.32	285	137	4	6	290	1	269	4e-77	248
rs:WP_024401972	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.92	288	140	3	5	292	3	280	4e-77	248
rs:XP_008615547	hypothetical protein SDRG_11293 [Saprolegnia diclina VS20].	46.94	294	148	3	3	292	2	291	4e-77	248
rs:WP_044769449	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.22	288	142	3	5	292	3	280	4e-77	248
rs:WP_044926539	5,10-methylene-tetrahydrofolate cyclohydrolase [Enterococcus gilvus].	45.70	291	147	4	3	293	2	281	4e-77	248
sp:FOLD_XANAC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.92	288	138	3	4	289	13	290	4e-77	249
rs:WP_046349662	methenyltetrahydrofolate cyclohydrolase [Sphingomonas changbaiensis].	48.28	290	143	3	3	291	4	287	4e-77	249
rs:WP_024416593	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	4e-77	248
rs:WP_010373037	methenyltetrahydrofolate cyclohydrolase [Xanthomonas vasicola].	47.92	288	138	3	4	289	13	290	4e-77	249
rs:WP_044759565	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.06	289	143	3	5	293	3	281	5e-77	248
rs:WP_008790685	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Coprobacillus].	47.54	284	139	3	5	288	2	275	5e-77	248
rs:WP_016146397	hypothetical protein [Butyricicoccus pullicaecorum].	47.77	291	139	4	1	291	1	278	5e-77	248
rs:WP_046838939	5,10-methylene-tetrahydrofolate cyclohydrolase [Candidatus Synechococcus spongiarum].	46.90	290	149	2	3	291	2	287	5e-77	249
rs:WP_004028213	tetrahydrofolate dehydrogenase [Spiroplasma melliferum].	45.94	283	143	2	4	286	5	277	5e-77	248
rs:WP_000192093	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	46.90	290	144	3	4	293	3	282	5e-77	248
sp:FOLD_DESOH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.13	297	153	2	1	290	1	297	5e-77	249
rs:WP_024389423	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.22	288	142	3	5	292	3	280	5e-77	248
tr:E1Y816_9DELT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.13	308	151	4	1	290	1	308	5e-77	249
rs:WP_006344080	5,10-methylene-tetrahydrofolate dehydrogenase [Chlamydophila abortus].	46.18	288	149	3	5	291	2	284	5e-77	248
rs:WP_000192099	bifunctional protein FolD [Streptococcus pneumoniae].	46.90	290	144	3	4	293	3	282	5e-77	248
rs:WP_017698320	methenyltetrahydrofolate cyclohydrolase [Mycoplasma mycoides].	44.33	282	148	3	5	286	3	275	5e-77	248
rs:WP_021771626	tetrahydrofolate dehydrogenase [Mitsuokella sp. oral taxon 131].	45.76	295	148	3	1	293	1	285	5e-77	248
rs:WP_036168891	methenyltetrahydrofolate cyclohydrolase [Lysobacter dokdonensis].	48.63	292	138	3	3	292	12	293	5e-77	248
rs:WP_026064586	methenyltetrahydrofolate cyclohydrolase [Xanthomonas arboricola].	47.92	288	138	3	4	289	13	290	5e-77	248
rs:WP_045786971	methenyltetrahydrofolate cyclohydrolase [Ralstonia mannitolilytica].	47.26	292	143	4	1	292	1	281	5e-77	248
rs:WP_022969853	methenyltetrahydrofolate cyclohydrolase [Arenimonas oryziterrae].	48.96	288	135	3	1	286	1	278	5e-77	248
tr:Z9JJB6_XYLFS	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.95	292	140	3	3	292	12	293	5e-77	248
rs:WP_035731656	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase, partial [Bradyrhizobium].	47.75	289	145	2	1	289	3	285	5e-77	248
rs:WP_033708014	bifunctional protein FolD [Streptococcus pneumoniae].	46.90	290	144	3	4	293	3	282	5e-77	248
rs:WP_004256551	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus mitis].	46.90	290	144	3	4	293	3	282	5e-77	248
rs:WP_015587992	bifunctional protein FolD [Wolbachia endosymbiont of Drosophila simulans].	45.30	298	149	5	5	297	4	292	5e-77	248
rs:WP_020024218	methenyltetrahydrofolate cyclohydrolase [gamma proteobacterium SCGC AAA076-D02].	45.33	289	144	3	5	293	3	277	5e-77	248
rs:WP_000192085	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	46.90	290	144	3	4	293	3	282	5e-77	248
rs:WP_043945419	methenyltetrahydrofolate cyclohydrolase [Ralstonia solanacearum].	46.50	286	142	3	1	286	1	275	5e-77	248
rs:WP_000192104	tetrahydrofolate dehydrogenase [Streptococcus mitis].	46.90	290	144	3	4	293	3	282	5e-77	248
rs:WP_010382160	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Xanthomonas].	47.92	288	138	3	4	289	13	290	5e-77	248
rs:WP_020900264	tetrahydrofolate dehydrogenase [Streptococcus mitis].	46.90	290	144	3	4	293	3	282	5e-77	248
tr:A0A0E0N900_ORYRU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORUFI02G01560.1};	46.74	291	149	2	3	291	80	366	5e-77	251
rs:WP_000192097	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	46.90	290	144	3	4	293	3	282	5e-77	248
rs:WP_034525597	methenyltetrahydrofolate cyclohydrolase [Lactobacillus oryzae].	46.94	294	139	5	3	292	2	282	6e-77	248
rs:WP_023025508	bifunctional protein FolD [Mesoplasma florum].	46.37	289	146	3	5	293	3	282	6e-77	248
rs:WP_000192094	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	46.90	290	144	3	4	293	3	282	6e-77	248
rs:WP_046173799	5,10-methylene-tetrahydrofolate cyclohydrolase [Domibacillus indicus].	47.59	290	141	5	1	290	1	279	6e-77	248
rs:WP_015370805	methylenetetrahydrofolate dehydrogenase [Blattabacterium sp. (Blatta orientalis)].	42.36	288	162	3	3	289	2	286	6e-77	248
rs:WP_044756550	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.22	288	142	3	5	292	3	280	6e-77	248
sp:FOLD_EHRCR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.26	292	143	4	1	289	1	284	6e-77	248
sp:FOLD2_PSEMY	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.97	290	140	4	1	290	5	286	6e-77	248
rs:WP_004028983	methylenetetrahydrofolate dehydrogenase [Spiroplasma melliferum].	45.94	283	143	2	4	286	5	277	6e-77	248
rs:WP_036175705	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Massilia sp. 9096].	46.05	291	146	4	1	291	1	280	6e-77	248
rs:WP_029997381	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.22	288	142	3	5	292	3	280	6e-77	248
rs:WP_043901704	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus sp. DORA_10].	46.90	290	144	3	4	293	3	282	6e-77	248
tr:K7VHR5_MAIZE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AFW82632.1, ECO:0000313|EnsemblPlants:GRMZM2G150485_P01};	46.50	286	147	2	3	286	2	283	6e-77	249
rs:WP_044667944	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	6e-77	248
rs:WP_008098139	5,10-methylene-tetrahydrofolate dehydrogenase [Verrucomicrobiae bacterium DG1235].	46.15	286	150	2	4	288	2	284	6e-77	248
rs:WP_036237742	5,10-methylene-tetrahydrofolate cyclohydrolase [Massilia sp. JS1662].	46.74	291	144	4	1	291	1	280	6e-77	248
rs:WP_006065599	5,10-methylene-tetrahydrofolate dehydrogenase [Natronorubrum bangense].	46.50	286	151	2	4	289	3	286	6e-77	248
rs:WP_007517514	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus tigurinus].	47.08	291	144	3	3	293	2	282	6e-77	248
rs:WP_033541762	5,10-methylene-tetrahydrofolate cyclohydrolase [Planococcus sp. CAU13].	47.44	293	143	4	1	293	1	282	6e-77	248
tr:A0A0D3C506_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo4g187720.1};	45.55	292	149	4	5	292	65	350	7e-77	250
rs:WP_016959256	hypothetical protein [Enterovibrio norvegicus].	47.26	292	147	3	1	292	1	285	7e-77	248
rs:WP_004620258	5,10-methylene-tetrahydrofolate dehydrogenase [[Clostridium] papyrosolvens].	46.71	289	143	3	1	289	1	278	7e-77	248
rs:WP_000192083	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	46.90	290	144	3	4	293	3	282	7e-77	248
rs:WP_024387125	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.22	288	142	3	5	292	3	280	7e-77	248
tr:E0TQD3_STRZ6	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.90	290	144	3	4	293	10	289	7e-77	248
rs:XP_002879758	methylenetetrahydrofolate dehydrogenase [Arabidopsis lyrata subsp. lyrata].	45.67	289	151	2	5	291	63	347	7e-77	250
rs:WP_029179150	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.22	288	142	3	5	292	3	280	7e-77	248
tr:C1C6G1_STRP7	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.90	290	144	3	4	293	10	289	7e-77	248
rs:WP_006148862	MULTISPECIES: tetrahydrofolate dehydrogenase [Firmicutes].	46.55	290	145	3	4	293	3	282	7e-77	248
rs:WP_003432956	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	47.28	294	147	3	1	294	1	286	7e-77	248
rs:WP_032510585	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	48.04	281	136	3	5	285	3	273	7e-77	248
rs:XP_003566549	PREDICTED: bifunctional protein FolD 2 [Brachypodium distachyon].	45.39	293	154	2	3	293	2	290	7e-77	248
rs:XP_009141750	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X1 [Brassica rapa].	45.55	292	149	4	5	292	65	350	7e-77	250
rs:YP_003445985	FolD bifunctional protein; includes: methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase [Streptococcus mitis B6].	46.90	290	144	3	4	293	24	303	7e-77	248
rs:WP_032090966	methenyltetrahydrofolate cyclohydrolase [bacterium LF-3].	46.48	284	142	3	5	288	2	275	7e-77	248
rs:WP_000192078	bifunctional protein FolD [Streptococcus pneumoniae].	46.90	290	144	3	4	293	3	282	7e-77	248
rs:WP_023462535	5,10-methylene-tetrahydrofolate dehydrogenase [Asticcacaulis sp. YBE204].	48.29	292	139	4	3	289	5	289	7e-77	248
rs:WP_009602248	bifunctional methylenetetrahydrofolatedehydrogena se/ methenyltetrahydrofolate cyclohydrolase [Xanthomonas translucens].	48.11	291	139	3	1	289	10	290	7e-77	248
rs:WP_045738896	methenyltetrahydrofolate cyclohydrolase [Xanthomonas sp. MUS 060].	46.62	296	146	3	1	294	10	295	7e-77	248
rs:WP_024381537	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.22	288	142	3	5	292	3	280	7e-77	248
rs:XP_005823410	hypothetical protein GUITHDRAFT_158677 [Guillardia theta CCMP2712].	44.98	289	149	5	2	285	6	289	7e-77	248
rs:WP_036213958	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Massilia alkalitolerans].	46.39	291	145	3	1	291	1	280	7e-77	248
rs:WP_004265568	tetrahydrofolate dehydrogenase [Lactobacillus curvatus].	44.79	288	148	3	4	291	2	278	8e-77	248
rs:WP_022950956	5,10-methylene-tetrahydrofolate dehydrogenase [Leucothrix mucor].	45.33	289	153	2	3	291	2	285	8e-77	248
rs:WP_037943327	methenyltetrahydrofolate cyclohydrolase [Sulfitobacter sp. CB2047].	49.15	293	144	2	1	292	1	289	8e-77	248
rs:WP_007570413	methenyltetrahydrofolate cyclohydrolase [Patulibacter medicamentivorans].	46.21	290	152	1	1	290	1	286	8e-77	248
rs:XP_010935086	PREDICTED: bifunctional protein FolD 4, chloroplastic-like isoform X2 [Elaeis guineensis].	46.23	292	151	2	2	291	70	357	8e-77	250
rs:WP_044311507	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.28	294	147	3	1	294	1	286	8e-77	248
tr:H5Y928_9BRAD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.06	289	147	2	1	289	1	283	8e-77	249
rs:WP_014124133	tetrahydrofolate dehydrogenase [Tetragenococcus halophilus].	46.18	288	144	4	5	292	4	280	8e-77	248
rs:WP_024652291	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.28	294	147	3	1	294	1	286	8e-77	248
rs:XP_005651939	hypothetical protein COCSUDRAFT_26703 [Coccomyxa subellipsoidea C-169].	41.95	298	167	2	2	293	12	309	8e-77	248
rs:WP_006909781	methenyltetrahydrofolate cyclohydrolase [Cyanobium sp. PCC 7001].	47.70	283	138	3	6	288	5	277	8e-77	248
rs:WP_026784017	methenyltetrahydrofolate cyclohydrolase [Pleomorphomonas koreensis].	49.49	293	141	3	1	293	1	286	8e-77	248
rs:WP_038644621	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium huakuii].	47.46	295	139	5	3	289	2	288	8e-77	248
tr:A0A0C5J8A5_9RHOO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.95	296	148	4	1	295	1	285	8e-77	248
rs:WP_018695112	5,10-methylene-tetrahydrofolate dehydrogenase [Alistipes onderdonkii].	46.45	282	142	3	5	286	2	274	8e-77	248
rs:WP_020651679	hypothetical protein [Massilia niastensis].	45.73	293	148	3	1	293	1	282	8e-77	248
rs:WP_033048211	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas sp. GM33].	48.78	287	138	3	3	288	9	287	9e-77	248
rs:WP_017355614	methenyltetrahydrofolate cyclohydrolase [Stenotrophomonas maltophilia].	48.45	291	138	4	2	290	9	289	9e-77	248
tr:E8KCA3_9STRE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.90	290	144	3	4	293	24	303	9e-77	248
rs:WP_046304899	methenyltetrahydrofolate cyclohydrolase [Blochmannia endosymbiont of Camponotus (Colobopsis) obliquus].	43.49	292	155	2	1	292	1	282	9e-77	247
rs:WP_017664797	5,10-methylene-tetrahydrofolate dehydrogenase [Porphyrobacter sp. AAP82].	47.92	288	146	1	2	289	3	286	9e-77	248
rs:WP_012821355	5,10-methylene-tetrahydrofolate dehydrogenase [Blattabacterium sp. (Periplaneta americana)].	42.36	288	162	3	3	289	2	286	9e-77	248
rs:WP_033074492	methenyltetrahydrofolate cyclohydrolase [Sphingopyxis sp. MWB1].	45.17	290	155	1	2	291	4	289	9e-77	248
rs:WP_020027065	methenyltetrahydrofolate cyclohydrolase [gamma proteobacterium SCGC AAA076-E13].	45.67	289	143	3	5	293	3	277	9e-77	247
rs:WP_037498907	methenyltetrahydrofolate cyclohydrolase [Sphingomonas jaspsi].	47.08	291	148	2	1	291	1	285	9e-77	248
rs:XP_005718793	C-1-tetrahydrofolate synthase, cytoplasmic [Chondrus crispus].	45.33	289	149	3	5	291	13	294	9e-77	248
tr:A6XMY4_TRIMO	SubName: Full=5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methenyl-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:ABJ15726.1};	44.71	293	156	2	3	293	2	290	1e-76	248
rs:WP_027316813	methenyltetrahydrofolate cyclohydrolase [Microvirga flocculans].	45.86	290	151	3	1	289	1	285	1e-76	248
sp:FOLD_STRP2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.90	290	144	3	4	293	3	282	1e-76	247
rs:WP_022036018	bifunctional protein FolD [Roseburia sp. CAG:50].	48.24	284	136	3	3	286	2	274	1e-76	247
rs:WP_003474638	5,10-methylene-tetrahydrofolate dehydrogenase [Xanthomonas translucens].	48.11	291	139	3	1	289	10	290	1e-76	248
sp:FOLD_MESFL	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.37	289	146	3	5	293	3	282	1e-76	247
tr:I0SSZ9_STROR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.08	291	144	3	3	293	23	303	1e-76	248
rs:WP_045650882	methenyltetrahydrofolate cyclohydrolase [Gammaproteobacteria bacterium BRH_c0].	47.24	290	146	2	3	292	2	284	1e-76	247
rs:WP_029176852	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.57	288	141	3	5	292	3	280	1e-76	247
rs:WP_022421891	bifunctional protein FolD [Clostridium sp. CAG:307].	47.20	286	142	2	3	288	2	278	1e-76	247
rs:WP_044963456	methenyltetrahydrofolate cyclohydrolase [Eubacterium ramulus].	48.24	284	136	3	3	286	2	274	1e-76	247
rs:WP_020748393	5,10-methylene-tetrahydrofolate dehydrogenase [Ralstonia solanacearum].	47.20	286	140	3	1	286	1	275	1e-76	247
rs:WP_006149835	tetrahydrofolate dehydrogenase [Streptococcus infantis].	46.90	290	144	3	4	293	3	282	1e-76	247
rs:WP_008544688	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Pelagibacter sp. HTCC7211].	46.53	288	143	3	5	292	3	279	1e-76	247
rs:XP_002499544	predicted protein [Micromonas sp. RCC299].	45.21	292	154	2	3	292	44	331	1e-76	249
sp:FOLD_RALPJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.20	286	140	3	1	286	1	275	1e-76	247
rs:WP_010659146	5,10-methylene-tetrahydrofolate dehydrogenase [Ochrobactrum anthropi].	48.30	294	144	4	3	292	2	291	1e-76	248
rs:WP_000192077	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	46.55	290	145	3	4	293	3	282	1e-76	247
rs:WP_013729807	methenyltetrahydrofolate cyclohydrolase [Mycoplasma mycoides].	43.97	282	149	3	5	286	3	275	1e-76	247
rs:WP_000192112	tetrahydrofolate dehydrogenase [Streptococcus pseudopneumoniae].	46.55	290	145	3	4	293	3	282	1e-76	247
rs:WP_000192095	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	46.55	290	145	3	4	293	3	282	1e-76	247
rs:WP_046136132	methenyltetrahydrofolate cyclohydrolase [Devosia limi].	46.55	290	150	2	1	289	1	286	1e-76	248
rs:WP_024661294	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	46.94	294	148	3	1	294	1	286	1e-76	248
rs:WP_023380546	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. VLB120].	48.99	298	143	5	1	297	1	290	1e-76	248
rs:WP_018402174	methenyltetrahydrofolate cyclohydrolase [gamma proteobacterium SCGC AB-629-P17].	46.37	289	141	4	5	293	3	277	1e-76	247
rs:WP_040775919	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Massilia timonae].	46.39	291	145	3	1	291	1	280	1e-76	247
tr:B1IAZ5_STRPI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.90	290	144	3	4	293	10	289	1e-76	247
rs:WP_000192096	tetrahydrofolate dehydrogenase [Streptococcus mitis].	46.55	290	145	3	4	293	3	282	1e-76	247
tr:W1UHI0_9STRE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.90	290	144	3	4	293	24	303	1e-76	248
rs:WP_009240794	MULTISPECIES: bifunctional protein FolD [Bacteria].	47.20	286	140	3	1	286	1	275	1e-76	247
rs:WP_027681268	methenyltetrahydrofolate cyclohydrolase [Ralstonia sp. UNC404CL21Col].	47.20	286	140	3	1	286	1	275	1e-76	247
rs:WP_025087750	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus apodemi].	46.88	288	142	3	5	292	4	280	1e-76	247
rs:WP_028838261	methenyltetrahydrofolate cyclohydrolase [Thermomonas fusca].	48.29	292	139	3	1	290	15	296	1e-76	248
rs:WP_017532226	5,10-methylene-tetrahydrofolate dehydrogenase [Wolbachia endosymbiont of Diaphorina citri].	45.27	296	152	4	5	297	4	292	1e-76	247
rs:WP_003472502	5,10-methylene-tetrahydrofolate dehydrogenase [Xanthomonas translucens].	48.11	291	139	3	1	289	10	290	1e-76	248
sp:FOLD_WOLPP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.61	296	151	4	5	297	4	292	1e-76	247
rs:WP_039098132	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus curvatus].	45.23	283	144	3	4	286	2	273	1e-76	247
rs:WP_033835652	methenyltetrahydrofolate cyclohydrolase [Stenotrophomonas maltophilia].	48.28	290	138	4	3	290	10	289	1e-76	247
rs:WP_007207121	tetrahydrofolate dehydrogenase [Enterococcus italicus].	46.88	288	141	3	5	292	4	279	1e-76	247
rs:WP_027230275	methenyltetrahydrofolate cyclohydrolase [Phyllobacterium sp. UNC302MFCol5.2].	48.65	296	142	5	3	293	2	292	1e-76	248
rs:WP_013205871	5,10-methylene-tetrahydrofolate dehydrogenase [Ralstonia solanacearum].	46.15	286	143	3	1	286	1	275	1e-76	247
rs:WP_036173394	5,10-methylene-tetrahydrofolate cyclohydrolase [Lysinibacillus massiliensis].	46.37	289	144	4	5	293	3	280	1e-76	247
rs:WP_018461471	5,10-methylene-tetrahydrofolate dehydrogenase [Thermus oshimai].	46.37	289	139	4	1	289	1	273	1e-76	247
tr:I2IIK1_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.95	286	135	4	1	286	51	325	1e-76	249
rs:WP_046169089	methenyltetrahydrofolate cyclohydrolase [Devosia psychrophila].	46.21	290	151	2	1	289	1	286	1e-76	248
rs:WP_004847804	5,10-methylene-tetrahydrofolate dehydrogenase [[Ruminococcus] torques].	48.23	282	135	4	5	286	4	274	1e-76	247
sp:FOLD2_PSEU2	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.28	294	147	3	1	294	1	286	1e-76	247
rs:WP_046035451	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	48.44	289	140	3	3	290	15	295	1e-76	248
tr:A0A078FVA5_BRANA	SubName: Full=BnaA04g22120D protein {ECO:0000313|EMBL:CDY18375.1};	45.55	292	149	4	5	292	65	350	1e-76	249
gpu:LN847353_747	Methylenetetrahydrofolate dehydrogenase (NADP+) [Streptococcus pneumoniae]	46.90	290	144	3	4	293	10	289	1e-76	247
rs:WP_033688627	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	46.90	290	144	3	4	293	3	282	1e-76	247
rs:WP_036579170	methenyltetrahydrofolate cyclohydrolase [Ochrobactrum anthropi].	48.30	294	144	4	3	292	2	291	1e-76	247
tr:J3YT83_9ENTR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.15	286	144	2	6	291	1	276	1e-76	247
rs:WP_045443680	methenyltetrahydrofolate cyclohydrolase [alpha proteobacterium MA2].	47.10	293	150	2	1	292	1	289	1e-76	247
rs:WP_010745904	FolD protein [Enterococcus raffinosus].	46.05	291	146	4	3	293	2	281	2e-76	247
rs:XP_002946721	hypothetical protein VOLCADRAFT_103143 [Volvox carteri f. nagariensis].	44.86	292	155	2	3	292	85	372	2e-76	250
rs:WP_023941471	tetrahydrofolate dehydrogenase [Streptococcus pseudopneumoniae].	46.55	290	145	3	4	293	3	282	2e-76	247
rs:WP_000192109	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	46.90	290	144	3	4	293	3	282	2e-76	247
rs:WP_020028807	methenyltetrahydrofolate cyclohydrolase [gamma proteobacterium SCGC AAA076-F14].	45.67	289	143	3	5	293	3	277	2e-76	246
rs:WP_039597477	methenyltetrahydrofolate cyclohydrolase [Ralstonia sp. A12].	46.39	291	145	3	1	291	1	280	2e-76	247
tr:C6HTS0_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.10	282	142	2	5	286	7	278	2e-76	247
rs:WP_007356261	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Kamptonema].	45.96	285	148	2	2	286	5	283	2e-76	247
rs:WP_017375133	hypothetical protein [Enterobacteriaceae bacterium LSJC7].	47.93	290	137	3	4	293	3	278	2e-76	246
sp:FOLD_BUCBP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.27	291	158	2	1	291	1	281	2e-76	247
rs:WP_006596772	tetrahydrofolate dehydrogenase [Streptococcus australis].	47.06	289	143	3	5	293	4	282	2e-76	247
rs:WP_036587561	methenyltetrahydrofolate cyclohydrolase [Ochrobactrum anthropi].	48.30	294	144	4	3	292	2	291	2e-76	247
tr:A0A075GRM3_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.33	291	148	4	1	289	1	279	2e-76	247
rs:WP_033629455	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus oralis].	46.74	291	145	3	3	293	2	282	2e-76	247
rs:XP_005401364	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X4 [Chinchilla lanigera].	47.24	290	146	3	11	294	1	289	2e-76	247
rs:WP_010091935	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia].	47.90	286	138	3	1	286	1	275	2e-76	247
rs:WP_024638458	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.28	294	147	3	1	294	1	286	2e-76	247
rs:WP_016398093	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus].	47.55	286	140	3	4	289	3	278	2e-76	246
rs:WP_010406409	5,10-methylene-tetrahydrofolate dehydrogenase [Wolbachia endosymbiont of Nasonia vitripennis].	45.80	286	147	3	5	289	4	282	2e-76	247
tr:A0A0B5HDT4_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.58	294	148	3	1	294	4	285	2e-76	247
rs:WP_041431134	5,10-methylene-tetrahydrofolate cyclohydrolase [Synechococcus sp. PCC 6312].	45.10	286	151	2	1	286	4	283	2e-76	247
rs:WP_025314992	methenyltetrahydrofolate cyclohydrolase [Gilliamella apicola].	46.74	291	144	3	1	291	1	280	2e-76	246
rs:WP_037965050	methenyltetrahydrofolate cyclohydrolase [Sulfitobacter pontiacus].	48.81	293	145	2	1	292	1	289	2e-76	247
tr:A0A091D7S5_FUKDA	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFO26295.1};	46.31	298	153	3	3	294	71	367	2e-76	249
tr:E1M448_STRMT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.90	290	144	3	4	293	24	303	2e-76	247
rs:WP_027629072	5,10-methylene-tetrahydrofolate cyclohydrolase [[Clostridium] cellobioparum].	47.92	288	139	3	1	288	1	277	2e-76	246
tr:M5MSH7_STREE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.90	290	144	3	4	293	24	303	2e-76	247
rs:WP_046861880	methenyltetrahydrofolate cyclohydrolase [Microvirga sp. JC119].	46.23	292	151	3	1	291	1	287	2e-76	247
rs:WP_022679919	5,10-methylene-tetrahydrofolate dehydrogenase [Sandarakinorhabdus limnophila].	47.80	295	143	4	1	290	1	289	2e-76	247
rs:WP_043832970	methenyltetrahydrofolate cyclohydrolase, partial [Roseomonas aerilata].	44.98	289	145	3	1	289	1	275	2e-76	246
rs:WP_027890505	5,10-methylene-tetrahydrofolate cyclohydrolase [Megamonas hypermegale].	44.07	295	153	3	1	293	1	285	2e-76	247
rs:WP_029453945	methenyltetrahydrofolate cyclohydrolase [Candidatus Pelagibacter ubique].	45.83	288	145	3	5	292	3	279	2e-76	246
rs:WP_006433194	5,10-methylene-tetrahydrofolate dehydrogenase [Natrinema versiforme].	43.89	303	149	4	4	289	3	301	2e-76	247
rs:WP_019723635	tetrahydrofolate dehydrogenase [Enterococcus mundtii].	47.57	288	140	4	3	290	2	278	2e-76	246
rs:XP_011018910	PREDICTED: bifunctional protein FolD 1, mitochondrial [Populus euphratica].	46.60	294	149	4	2	292	74	362	2e-76	249
tr:A0A081B838_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.10	293	150	2	1	292	6	294	2e-76	247
rs:WP_025662966	methenyltetrahydrofolate cyclohydrolase [alpha proteobacterium SCGC AAA288-G21].	47.04	287	141	3	6	292	4	279	2e-76	246
rs:WP_041485385	methenyltetrahydrofolate cyclohydrolase, partial [alpha proteobacterium HIMB59].	47.26	292	144	3	6	291	5	292	2e-76	247
rs:WP_026624916	methenyltetrahydrofolate cyclohydrolase [Eggerthia catenaformis].	44.18	292	153	3	5	296	2	283	2e-76	246
tr:A0A096AM43_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.55	290	145	3	4	293	24	303	2e-76	247
rs:WP_003276124	5,10-methylene-tetrahydrofolate dehydrogenase [Ralstonia solanacearum].	46.85	286	141	3	1	286	1	275	2e-76	246
rs:WP_025171944	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	46.55	290	145	3	4	293	3	282	2e-76	246
rs:WP_024399536	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.22	288	142	3	5	292	3	280	2e-76	246
sp:FOLD_CHLCV	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.33	289	152	3	5	292	2	285	2e-76	246
rs:XP_011102505	mis1p [Saccharomyces arboricola H-6].	47.60	292	146	3	5	293	37	324	2e-76	262
rs:XP_011101982	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X1 [Sesamum indicum].	46.46	297	150	3	2	293	69	361	2e-76	249
rs:XP_011622743	PREDICTED: bifunctional protein FolD 4, chloroplastic [Amborella trichopoda].	45.02	291	154	2	3	291	23	309	2e-76	247
rs:WP_028860596	methenyltetrahydrofolate cyclohydrolase [Ralstonia solanacearum].	47.20	286	140	3	1	286	1	275	2e-76	246
rs:WP_034286087	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. 72].	47.20	286	140	4	1	286	1	275	2e-76	246
rs:WP_042750844	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	46.55	290	145	3	4	293	3	282	2e-76	246
rs:WP_029774955	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [beta proteobacterium JGI 0001003-N18].	52.81	231	109	0	56	286	2	232	2e-76	245
rs:XP_011396488	Bifunctional protein FolD [Auxenochlorella protothecoides].	46.97	264	134	2	32	293	10	269	2e-76	246
rs:WP_039009838	methenyltetrahydrofolate cyclohydrolase [Xanthomonas translucens].	48.11	291	139	3	1	289	10	290	2e-76	247
rs:WP_006214283	FolD protein [Brucella abortus].	48.30	294	144	4	3	292	2	291	2e-76	247
rs:WP_028628069	methenyltetrahydrofolate cyclohydrolase [Pseudomonas resinovorans].	48.44	289	141	3	2	290	6	286	2e-76	247
tr:B2INU1_STRPS	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.90	290	144	3	4	293	24	303	2e-76	247
rs:WP_001843924	tetrahydrofolate dehydrogenase [Streptococcus pneumoniae].	46.90	290	144	3	4	293	24	303	2e-76	247
rs:WP_024020208	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium sp. C100].	48.25	286	144	1	4	289	5	286	2e-76	247
rs:WP_032660769	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	46.94	294	148	3	1	294	1	286	2e-76	247
rs:WP_046789816	methenyltetrahydrofolate cyclohydrolase [Salinicoccus halodurans].	45.86	290	144	4	1	290	1	277	2e-76	246
tr:A0A098ZSC0_STREE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.55	286	140	3	4	289	24	299	2e-76	247
rs:WP_004056071	5,10-methylene-tetrahydrofolate dehydrogenase [Halococcus morrhuae].	44.74	304	151	2	5	292	4	306	3e-76	247
rs:WP_010300971	methenyltetrahydrofolate cyclohydrolase [Candidatus Odyssella thessalonicensis].	44.98	289	148	2	3	291	2	279	3e-76	246
rs:WP_043605046	methenyltetrahydrofolate cyclohydrolase [Novosphingobium sp. Rr 2-17].	46.76	293	149	3	1	292	2	288	3e-76	247
rs:WP_027906966	methenyltetrahydrofolate cyclohydrolase [Pseudomonas taiwanensis].	48.66	298	144	5	1	297	1	290	3e-76	247
rs:WP_008895430	5,10-methylene-tetrahydrofolate dehydrogenase [Haloterrigena salina].	47.20	286	149	2	4	289	3	286	3e-76	246
rs:WP_027972005	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus plurextorum].	46.74	291	145	2	3	293	2	282	3e-76	246
rs:WP_002332077	FolD protein [Enterococcus faecium].	46.88	288	142	3	3	290	2	278	3e-76	246
rs:XP_002184781	predicted protein [Phaeodactylum tricornutum CCAP 1055/1].	44.33	300	154	3	1	291	1	296	3e-76	247
rs:WP_010233902	5,10-methylene-tetrahydrofolate dehydrogenase [Citromicrobium bathyomarinum].	47.42	291	149	1	1	291	1	287	3e-76	246
rs:WP_033684958	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	46.55	290	145	3	4	293	3	282	3e-76	246
rs:WP_009394919	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas putida].	49.13	287	138	3	4	290	8	286	3e-76	246
rs:WP_010116227	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia oklahomensis].	48.95	286	135	4	1	286	1	275	3e-76	246
sp:FOLD_STRSY	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.22	288	142	3	5	292	3	280	3e-76	246
tr:J9Z065_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.26	292	144	3	6	291	5	292	3e-76	247
rs:WP_019860340	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium loti].	47.12	295	140	5	3	289	2	288	3e-76	246
rs:WP_020053290	hypothetical protein [alpha proteobacterium SCGC AAA015-N04].	44.98	289	152	2	4	289	3	287	3e-76	247
rs:WP_007952710	5,10-methylene-tetrahydrofolate dehydrogenase [Pelosinus fermentans].	46.42	293	143	4	1	290	1	282	3e-76	246
rs:WP_036214755	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Massilia sp. LC238].	46.05	291	146	3	1	291	1	280	3e-76	246
rs:WP_037604019	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus salivarius].	48.62	290	139	3	3	292	2	281	3e-76	246
rs:WP_031370693	methenyltetrahydrofolate cyclohydrolase [Lysobacter antibioticus].	47.95	292	140	3	3	292	11	292	3e-76	246
rs:WP_003773856	methenyltetrahydrofolate cyclohydrolase, partial [Neisseria elongata].	49.80	253	113	3	40	290	1	241	3e-76	244
rs:XP_005703610	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase [Galdieria sulphuraria].	44.33	291	156	2	3	291	59	345	3e-76	248
rs:WP_031499635	methenyltetrahydrofolate cyclohydrolase [Bryobacter aggregatus].	44.14	290	147	3	3	292	2	276	3e-76	246
rs:WP_035079076	methenyltetrahydrofolate cyclohydrolase [Devosia riboflavina].	46.90	290	149	2	1	289	1	286	3e-76	246
sp:FOLD_PELUB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.53	288	143	3	5	292	3	279	3e-76	246
rs:WP_019223404	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella rattaustraliani].	46.33	300	148	6	4	296	3	296	3e-76	246
sp:FOLD_JANMA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.77	291	141	3	1	291	1	280	3e-76	246
rs:WP_027082187	methenyltetrahydrofolate cyclohydrolase [Lysobacter sp. URHA0019].	47.42	291	141	3	2	290	7	287	3e-76	246
rs:WP_013661565	5,10-methylene-tetrahydrofolate dehydrogenase [Marinomonas mediterranea].	48.14	295	143	3	6	297	10	297	3e-76	246
rs:WP_035005700	methenyltetrahydrofolate cyclohydrolase [Bartonella rochalimae].	46.26	294	146	5	5	292	4	291	3e-76	246
rs:WP_028630324	methenyltetrahydrofolate cyclohydrolase [Pseudomonas resinovorans].	48.95	286	138	3	5	290	9	286	3e-76	246
rs:XP_010427271	PREDICTED: bifunctional protein FolD 4, chloroplastic-like isoform X2 [Camelina sativa].	49.61	254	122	2	40	291	62	311	3e-76	247
rs:WP_010405277	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas echinoides].	46.74	291	144	3	1	291	1	280	3e-76	246
rs:WP_029541060	5,10-methylene-tetrahydrofolate cyclohydrolase [Selenomonas ruminantium].	45.76	295	154	2	1	293	1	291	3e-76	246
rs:XP_008924547	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Manacus vitellinus].	49.82	281	133	4	22	295	79	358	3e-76	249
rs:WP_012935057	methenyltetrahydrofolate cyclohydrolase [Conexibacter woesei].	43.79	290	152	2	1	290	1	279	3e-76	246
rs:WP_028969808	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. URHD0057].	45.70	291	153	2	1	291	1	286	3e-76	246
sp:FOLD_RUTMC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.17	290	145	3	4	293	2	277	3e-76	246
rs:WP_046922106	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus ruminis].	45.05	293	150	4	4	296	3	284	3e-76	246
rs:WP_024375752	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.22	288	142	3	5	292	3	280	3e-76	246
rs:WP_008164011	5,10-methylene-tetrahydrofolate dehydrogenase [Natronorubrum sulfidifaciens].	46.15	286	152	2	4	289	3	286	3e-76	246
sp:FOLD_OCHA4	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.30	294	144	4	3	292	2	291	3e-76	246
rs:WP_018370867	tetrahydrofolate dehydrogenase [Streptococcus massiliensis].	47.40	289	142	3	5	293	3	281	3e-76	246
tr:U2Q0Z9_EUBRA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.24	284	136	3	3	286	32	304	3e-76	247
rs:WP_046719552	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	46.94	294	148	3	1	294	1	286	3e-76	246
rs:WP_040725435	5,10-methylene-tetrahydrofolate cyclohydrolase [Oxalobacteraceae bacterium IMCC9480].	46.21	290	145	3	1	290	1	279	4e-76	246
sp:FOLD_SPHAL	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.33	289	154	1	3	291	8	292	4e-76	246
rs:WP_035369909	methenyltetrahydrofolate cyclohydrolase [Acholeplasma hippikon].	47.86	280	131	3	5	284	2	266	4e-76	246
rs:WP_017709136	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	47.28	294	147	3	1	294	1	286	4e-76	246
tr:A0A0C1NFQ2_9CYAN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.15	292	160	2	2	293	5	290	4e-76	246
tr:V8I8E8_STRMT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.55	290	145	3	4	293	24	303	4e-76	246
rs:WP_013447977	methenyltetrahydrofolate cyclohydrolase [Mycoplasma leachii].	43.62	282	150	3	5	286	3	275	4e-76	246
tr:A0A085F2B8_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.05	291	146	3	1	291	1	280	4e-76	246
tr:K9E0U2_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.39	291	145	3	1	291	17	296	4e-76	247
rs:WP_017971351	hypothetical protein [alpha proteobacterium SCGC AAA027-L15].	45.45	286	149	2	5	290	2	280	4e-76	246
rs:WP_027155554	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. WSM2561].	47.46	295	139	5	3	289	2	288	4e-76	246
sp:FOLD_CHLAB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.83	288	150	3	5	291	2	284	4e-76	246
rs:WP_004804393	hypothetical protein [Eggerthia catenaformis].	44.18	292	153	3	5	296	2	283	4e-76	246
rs:WP_026200104	methenyltetrahydrofolate cyclohydrolase [Acetobacter aceti].	46.10	295	151	4	3	296	4	291	4e-76	246
rs:WP_008832921	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonadaceae].	47.24	290	148	2	3	292	2	286	4e-76	246
rs:XP_010456259	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X2 [Camelina sativa].	49.61	254	122	2	40	291	62	311	4e-76	247
tr:K9RRQ8_SYNP3	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.10	286	151	2	1	286	33	312	4e-76	247
tr:A0A0D6MXQ1_ACEAC	SubName: Full=Bifunctional [5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase] {ECO:0000313|EMBL:GAN58113.1};	46.10	295	151	4	3	296	5	292	4e-76	246
rs:WP_000192100	tetrahydrofolate dehydrogenase [Streptococcus sp. M334].	46.21	290	146	2	4	293	3	282	4e-76	246
tr:R2P770_9ENTE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.05	291	146	4	3	293	4	283	4e-76	246
rs:WP_007741157	5,10-methylene-tetrahydrofolate dehydrogenase [Halococcus thailandensis].	45.83	288	154	2	5	292	4	289	4e-76	246
rs:WP_024676511	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.62	294	146	3	1	294	1	286	4e-76	246
rs:WP_004037870	5,10-methylene-tetrahydrofolate dehydrogenase [Methanofollis liminatans].	47.92	288	136	4	5	292	2	275	4e-76	246
rs:WP_036244892	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Massilia sp. BSC265].	46.05	291	146	3	1	291	1	280	4e-76	245
tr:A0A0D6QWP1_ARACU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:JAG95982.1};	45.21	292	154	2	3	292	114	401	4e-76	249
rs:WP_023904139	methylenetetrahydrofolate dehydrogenase [Xanthomonas hortorum].	47.92	288	138	3	4	289	13	290	4e-76	246
rs:WP_046482407	methenyltetrahydrofolate cyclohydrolase [Oceanospirillaceae bacterium ASP10-02a].	46.34	287	148	2	3	289	7	287	4e-76	246
sp:FOLD_METC4	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.21	290	149	2	1	290	1	283	4e-76	246
rs:WP_044765345	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	47.22	288	142	3	5	292	3	280	4e-76	245
rs:WP_018393884	hypothetical protein [Bacillus sp. 37MA].	47.20	286	140	4	1	286	1	275	5e-76	246
sp:FOLD_RHOS5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.95	292	145	2	1	292	1	285	5e-76	246
rs:XP_003678147	hypothetical protein NCAS_0I01350 [Naumovozyma castellii CBS 4309].	46.05	291	150	3	6	293	33	319	5e-76	261
tr:A0A0B7MXV1_9FUNG	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CEP07759.1};	46.26	294	151	3	1	291	1	290	5e-76	261
rs:WP_021779543	methylenetetrahydrofolate dehydrogenase [Halarchaeum acidiphilum].	47.72	285	147	2	5	289	15	297	5e-76	246
rs:WP_028044274	methenyltetrahydrofolate cyclohydrolase [Candidatus Stoquefichus massiliensis].	46.64	283	141	3	6	288	3	275	5e-76	245
rs:WP_009554632	methylenetetrahydrofolate dehydrogenase [Lactobacillus saerimneri].	47.92	288	139	3	5	292	4	280	5e-76	245
rs:WP_020222688	5,10-methylene-tetrahydrofolate dehydrogenase [Halarchaeum acidiphilum].	47.72	285	147	2	5	289	4	286	5e-76	246
rs:WP_003717327	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus vaginalis].	46.15	286	141	4	3	286	2	276	5e-76	246
rs:WP_033680061	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	46.21	290	146	3	4	293	3	282	5e-76	246
rs:WP_027055031	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium loti].	47.46	295	139	5	3	289	2	288	5e-76	246
tr:U1XGD4_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.62	294	146	4	3	292	8	297	5e-76	246
rs:WP_017943366	hypothetical protein [alpha proteobacterium SCGC AAA027-C06].	45.10	286	150	2	5	290	2	280	5e-76	245
rs:WP_017702803	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	47.28	294	147	3	1	294	1	286	5e-76	246
rs:WP_005738869	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae group].	47.62	294	146	3	1	294	1	286	5e-76	246
rs:WP_041008802	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium plurifarium].	47.96	294	137	5	4	289	3	288	5e-76	246
rs:WP_018001196	5,10-methylene-tetrahydrofolate dehydrogenase [Paracoccus sp. N5].	46.58	292	149	2	1	292	1	285	5e-76	246
rs:WP_001719797	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Salmonella enterica].	52.65	245	106	3	45	289	1	235	5e-76	244
rs:WP_034709533	5,10-methylene-tetrahydrofolate cyclohydrolase [Enterococcus malodoratus].	46.05	291	146	4	3	293	2	281	5e-76	246
rs:WP_039758040	methenyltetrahydrofolate cyclohydrolase [Bartonella queenslandensis].	45.58	294	148	5	4	291	3	290	5e-76	246
rs:WP_029351126	methenyltetrahydrofolate cyclohydrolase [Bosea sp. 117].	45.86	290	151	2	4	293	5	288	5e-76	246
rs:WP_025038450	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. DOA9].	48.08	287	141	3	5	291	16	294	5e-76	246
rs:WP_046980894	methenyltetrahydrofolate cyclohydrolase [Xanthomonas hyacinthi].	47.12	295	144	3	1	293	10	294	5e-76	246
rs:WP_017970175	hypothetical protein [alpha proteobacterium SCGC AAA027-J10].	45.45	286	149	2	5	290	2	280	5e-76	245
rs:WP_009834903	5,10-methylene-tetrahydrofolate dehydrogenase [Marinomonas sp. MED121].	48.96	288	140	2	6	293	5	285	5e-76	245
rs:WP_015241053	5,10-methylene-tetrahydrofolate dehydrogenase [Sinorhizobium meliloti].	48.80	291	141	4	5	291	4	290	5e-76	246
tr:A0A0D2TUX2_GOSRA	SubName: Full=Gossypium raimondii chromosome 8, whole genome shotgun sequence {ECO:0000313|EMBL:KJB47090.1};	42.11	323	151	3	3	293	9	327	5e-76	247
tr:I9C6A6_9SPHN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.76	293	149	3	1	292	20	306	6e-76	246
rs:WP_007930584	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pelosinus].	46.42	293	143	4	1	290	1	282	6e-76	246
rs:XP_009134389	PREDICTED: bifunctional protein FolD 4, chloroplastic-like [Brassica rapa].	46.53	288	148	2	6	291	60	343	6e-76	247
tr:D1AX33_STRM9	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.83	290	147	3	1	288	1	279	6e-76	245
rs:WP_022329272	bifunctional protein FolD [Firmicutes bacterium CAG:313].	45.30	287	146	2	5	291	3	278	6e-76	245
rs:WP_029601712	methenyltetrahydrofolate cyclohydrolase [Halobiforma lacisalsi].	46.71	289	152	2	1	289	4	290	6e-76	246
gpu:CP011770_507	methenyltetrahydrofolate cyclohydrolase [Croceicoccus naphthovorans]	48.78	287	140	3	6	291	5	285	6e-76	245
gpu:CP009518_65	Methylenetetrahydrofolate dehydrogenase (NADP+) [Methanococcoides methylutens MM1]	47.06	289	142	2	4	292	8	285	6e-76	245
rs:XP_006381293	hypothetical protein POPTR_0006s11490g [Populus trichocarpa].	46.60	294	149	4	2	292	70	358	6e-76	248
rs:XP_010517170	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X1 [Camelina sativa].	46.02	289	150	2	5	291	65	349	6e-76	248
rs:WP_020862910	bifunctional protein FolD [Mycoplasma mycoides].	43.62	282	150	3	5	286	3	275	6e-76	245
rs:WP_034689878	5,10-methylene-tetrahydrofolate cyclohydrolase [Enterococcus mundtii].	47.57	288	140	4	3	290	2	278	6e-76	245
rs:WP_040941252	methenyltetrahydrofolate cyclohydrolase [Xanthomonas campestris].	48.07	285	136	3	7	289	16	290	6e-76	245
sp:FOLD_XANC8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.07	285	136	3	7	289	16	290	6e-76	245
rs:WP_035903208	hypothetical protein [Fusobacterium necrophorum].	43.42	281	149	3	4	284	2	272	7e-76	245
tr:Q4RSN0_TETNG	SubName: Full=Chromosome 12 SCAF14999, whole genome shotgun sequence {ECO:0000313|EMBL:CAG08602.1}; Flags: Fragment;	43.43	327	150	5	2	294	3	328	7e-76	246
rs:WP_004269799	5,10-methylene-tetrahydrofolate dehydrogenase [Streptococcus mitis].	46.21	290	146	3	4	293	3	282	7e-76	245
rs:WP_021194653	5,10-methylene-tetrahydrofolate dehydrogenase [Ralstonia sp. AU12-08].	46.39	291	145	3	1	291	1	280	7e-76	245
rs:WP_004888309	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas viridiflava].	47.75	289	143	3	3	291	4	284	7e-76	246
rs:WP_006470582	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Ochrobactrum].	47.62	294	146	4	3	292	2	291	7e-76	246
rs:WP_045086327	methenyltetrahydrofolate cyclohydrolase [Candidatus Evansia muelleri].	42.07	290	158	2	1	290	1	280	7e-76	245
rs:WP_020168924	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Pelagibacter ubique].	46.53	288	143	3	5	292	3	279	7e-76	245
rs:WP_006109726	5,10-methylene-tetrahydrofolate dehydrogenase [Natrialba asiatica].	46.85	286	150	2	4	289	3	286	7e-76	246
rs:WP_046017306	methenyltetrahydrofolate cyclohydrolase [Marinomonas sp. S3726].	48.96	288	140	2	6	293	5	285	7e-76	245
rs:WP_025021856	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus hayakitensis].	45.39	293	149	3	1	293	1	282	7e-76	245
rs:WP_016329693	5,10-methylene-tetrahydrofolate dehydrogenase [Thermus oshimai].	46.02	289	140	4	1	289	1	273	7e-76	245
gp:HB883605_1	Sequence 16280 from Patent EP2096177. [Oryza sativa]	46.08	293	151	3	3	293	2	289	7e-76	245
rs:WP_019954770	5,10-methylene-tetrahydrofolate dehydrogenase [Loktanella vestfoldensis].	47.26	292	148	2	1	292	1	286	7e-76	245
sp:FOLD2_RHIME	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.80	291	141	4	5	291	4	290	7e-76	246
rs:WP_018426556	5,10-methylene-tetrahydrofolate dehydrogenase [Hoeflea sp. 108].	48.12	293	143	5	3	291	2	289	8e-76	245
sp:FOLD_RHOS4	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.26	292	147	2	1	292	1	285	8e-76	245
rs:WP_039576736	methenyltetrahydrofolate cyclohydrolase [Xanthomonas axonopodis].	47.57	288	139	3	4	289	13	290	8e-76	246
tr:E9FL33_9STRE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.21	290	146	2	4	293	10	289	8e-76	245
rs:WP_037620396	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus].	48.62	290	139	3	3	292	2	281	8e-76	245
rs:WP_027073256	methenyltetrahydrofolate cyclohydrolase [Luteimonas sp. J29].	47.57	288	139	3	1	286	1	278	8e-76	245
rs:WP_040988145	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium plurifarium].	47.62	294	138	5	4	289	3	288	8e-76	245
rs:WP_019981643	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. Amel2xE9].	43.69	293	155	4	1	293	1	283	8e-76	245
rs:WP_027352552	methenyltetrahydrofolate cyclohydrolase [Desulfosarcina sp. BuS5].	46.80	297	151	2	1	290	1	297	8e-76	246
tr:T1B5T8_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EQD63808.1};	53.60	250	106	2	41	290	1	240	8e-76	243
rs:WP_025091015	methenyltetrahydrofolate cyclohydrolase [Ochrobactrum intermedium].	47.62	294	146	4	3	292	2	291	8e-76	245
rs:WP_008632548	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Thermus].	45.67	289	141	4	1	289	1	273	8e-76	245
rs:XP_011711939	PREDICTED: LOW QUALITY PROTEIN: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Macaca nemestrina].	46.80	297	149	4	3	291	37	332	8e-76	247
rs:WP_019236745	5,10-methylene-tetrahydrofolate dehydrogenase [Wolbachia pipientis].	44.93	296	153	4	5	297	4	292	9e-76	245
rs:WP_013849824	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium chlorophenolicum].	47.57	288	144	3	3	290	2	282	9e-76	245
rs:WP_017523378	5,10-methylene-tetrahydrofolate dehydrogenase [Pusillimonas noertemannii].	46.50	286	142	3	1	286	1	275	9e-76	245
rs:WP_036902634	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. MIT 0601].	44.76	286	153	2	6	291	5	285	9e-76	245
tr:X0YST4_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S38652 {ECO:0000313|EMBL:GAG51433.1}; Flags: Fragment;	53.88	206	95	0	87	292	1	206	9e-76	242
rs:WP_000192106	tetrahydrofolate dehydrogenase [Streptococcus mitis].	46.55	290	145	3	4	293	3	282	9e-76	245
sp:FOLD1_RUBXD	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.64	289	147	4	3	290	2	278	9e-76	245
rs:WP_033683441	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus mitis].	47.55	286	140	3	4	289	3	278	9e-76	245
rs:WP_036133889	methenyltetrahydrofolate cyclohydrolase [Lysobacter daejeonensis].	48.28	290	138	3	3	290	8	287	9e-76	245
rs:WP_035745764	methenyltetrahydrofolate cyclohydrolase [Haematobacter missouriensis].	45.21	292	154	2	1	292	1	286	9e-76	245
rs:WP_005962926	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium necrophorum].	43.42	281	149	3	4	284	2	272	9e-76	245
rs:WP_006997602	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Pelagibacter ubique].	46.18	288	144	3	5	292	3	279	9e-76	244
rs:WP_009856190	5,10-methylene-tetrahydrofolate dehydrogenase [Rubrivivax benzoatilyticus].	45.89	292	144	4	1	292	1	278	9e-76	244
rs:WP_046741742	methenyltetrahydrofolate cyclohydrolase [Lampropedia sp. CT6].	48.43	287	139	4	6	290	13	292	9e-76	245
sp:FOLD_EHRCJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.08	291	145	3	1	289	1	284	1e-75	245
rs:WP_044771069	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	46.53	288	144	3	5	292	3	280	1e-75	244
rs:WP_016491359	methylenetetrahydrofolate dehydrogenase [Pseudomonas resinovorans].	48.43	287	140	3	4	290	8	286	1e-75	245
rs:WP_016624158	tetrahydrofolate dehydrogenase [Enterococcus faecalis].	46.15	286	143	4	5	290	4	278	1e-75	244
rs:WP_022734562	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Pelagibacter ubique].	45.14	288	147	2	5	292	2	278	1e-75	244
rs:WP_002805762	5,10-methylene-tetrahydrofolate dehydrogenase [Xanthomonas fragariae].	47.42	291	141	3	4	292	13	293	1e-75	245
tr:B5VE47_YEAS6	SubName: Full=YBR084Wp-like protein {ECO:0000313|EMBL:EDZ73798.1}; Flags: Fragment;	46.23	292	150	3	5	293	37	324	1e-75	256
rs:WP_036103105	methenyltetrahydrofolate cyclohydrolase [Lysobacter capsici].	48.28	290	138	3	3	290	8	287	1e-75	245
rs:WP_016994733	5,10-methylene-tetrahydrofolate dehydrogenase [Lysinibacillus boronitolerans].	46.42	293	146	3	1	293	1	282	1e-75	244
rs:WP_023800285	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. L48C026A00].	47.80	295	138	5	3	289	2	288	1e-75	245
rs:WP_021062091	5,10-methylene-tetrahydrofolate dehydrogenase [Halonotius sp. J07HN6].	50.80	250	122	1	43	292	3	251	1e-75	244
tr:E6YU16_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.58	294	148	5	5	292	4	291	1e-75	245
rs:WP_004182938	tetrahydrofolate dehydrogenase [Streptococcus salivarius].	48.28	290	140	3	3	292	2	281	1e-75	244
rs:WP_027993872	bifunctional protein FolD [Sinorhizobium meliloti].	48.80	291	141	4	5	291	4	290	1e-75	245
rs:WP_005958256	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium necrophorum].	43.42	281	149	3	4	284	2	272	1e-75	245
sp:FOLD_RALSO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.85	286	141	3	1	286	1	275	1e-75	244
rs:WP_023068350	tetrahydrofolate dehydrogenase [Lyngbya aestuarii].	47.08	291	148	2	3	293	2	286	1e-75	244
rs:WP_020680006	5,10-methylene-tetrahydrofolate dehydrogenase [Marinobacterium rhizophilum].	46.23	292	151	2	1	292	1	286	1e-75	245
rs:WP_022332478	bifunctional protein FolD [Alistipes sp. CAG:29].	48.68	265	127	3	22	286	4	259	1e-75	244
tr:G2SNF0_LACRR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.59	296	153	4	1	296	3	287	1e-75	244
tr:F1W0U7_9BURK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.21	290	145	3	1	290	48	326	1e-75	246
rs:WP_022819926	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium russii].	43.25	289	152	4	5	292	2	279	1e-75	244
rs:WP_024844019	methenyltetrahydrofolate cyclohydrolase [Paracoccus pantotrophus].	46.92	292	148	2	1	292	1	285	1e-75	245
rs:WP_041794250	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptobacillus moniliformis].	45.10	286	144	3	5	288	1	275	1e-75	244
rs:WP_024656283	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.62	294	146	3	1	294	1	286	1e-75	245
rs:WP_007696084	5,10-methylene-tetrahydrofolate dehydrogenase [Halococcus hamelinensis].	46.71	289	152	2	4	292	3	289	1e-75	245
sp:FOLD_RHORT	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.80	295	144	4	1	290	1	290	1e-75	245
rs:WP_040468121	methenyltetrahydrofolate cyclohydrolase [Lactobacillus gastricus].	46.23	292	144	5	4	293	8	288	1e-75	244
rs:WP_009211147	5,10-methylene-tetrahydrofolate dehydrogenase [Aurantimonas manganoxydans].	48.18	303	136	7	3	292	4	298	1e-75	245
rs:WP_008637076	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillaceae].	46.74	291	143	3	1	291	1	279	1e-75	244
rs:WP_024371518	5,10-methylene-tetrahydrofolate cyclohydrolase [Exiguobacterium sp. 8-11-1].	46.55	290	142	4	3	292	2	278	1e-75	244
rs:WP_024640943	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.28	294	147	3	1	294	1	286	1e-75	245
rs:WP_024680693	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.62	294	146	3	1	294	1	286	1e-75	245
rs:WP_041819950	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus ruminis].	45.05	293	150	4	4	296	3	284	1e-75	244
rs:WP_029563810	methenyltetrahydrofolate cyclohydrolase [alpha proteobacterium SCGC AAA240-E13].	47.39	287	140	3	6	292	4	279	1e-75	244
rs:WP_023041658	FolD protein [Fusobacterium nucleatum].	45.99	287	143	4	5	290	2	277	1e-75	244
tr:H4GJD6_9LACO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.23	292	144	5	4	293	17	297	1e-75	245
sp:FOLD_RHOS1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.26	292	147	2	1	292	1	285	1e-75	244
rs:WP_040645436	methenyltetrahydrofolate cyclohydrolase [Rubellimicrobium thermophilum].	47.24	290	146	3	3	292	2	284	1e-75	244
rs:WP_040768188	methenyltetrahydrofolate cyclohydrolase [Rhodopirellula maiorica].	47.51	301	138	5	3	290	2	295	1e-75	245
rs:WP_035386601	5,10-methylene-tetrahydrofolate cyclohydrolase [Exiguobacterium sp. S17].	46.02	289	143	4	3	291	2	277	1e-75	244
rs:WP_036186745	5,10-methylene-tetrahydrofolate cyclohydrolase [Lysinibacillus manganicus].	46.05	291	146	3	3	293	2	281	1e-75	244
rs:WP_029334795	5,10-methylene-tetrahydrofolate cyclohydrolase [Exiguobacterium aurantiacum].	46.55	290	142	4	3	292	2	278	1e-75	244
rs:WP_014507888	bifunctional protein FolD [Xanthomonas campestris].	47.72	285	137	3	7	289	16	290	1e-75	244
rs:WP_024890222	methenyltetrahydrofolate cyclohydrolase [Luteimonas huabeiensis].	47.39	287	139	3	2	286	8	284	1e-75	244
rs:WP_026618279	methenyltetrahydrofolate cyclohydrolase [Ensifer sp. WSM1721].	48.79	289	140	4	5	289	4	288	1e-75	245
tr:A0A0C1ZAK1_9DELT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.98	289	152	3	2	290	3	284	1e-75	244
tr:F3ESY8_PSEA0	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.78	293	139	5	1	291	1	281	2e-75	244
tr:K1YYH5_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.39	293	142	5	4	293	2	279	2e-75	244
rs:WP_037532630	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. Ant20].	48.45	291	139	3	1	291	1	280	2e-75	244
rs:WP_019333040	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	47.28	294	147	3	1	294	1	286	2e-75	245
tr:I1CPJ4_RHIO9	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EIE90374.1};	45.17	290	152	3	5	291	3	288	2e-75	259
rs:XP_010113030	Bifunctional protein FolD [Morus notabilis].	45.05	293	155	2	2	292	78	366	2e-75	247
sp:FOLD_THET2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.67	289	141	4	1	289	1	273	2e-75	244
rs:WP_008922735	5,10-methylene-tetrahydrofolate dehydrogenase [Burkholderia sp. H160].	48.95	286	135	3	1	286	1	275	2e-75	244
rs:WP_039212217	5,10-methylene-tetrahydrofolate cyclohydrolase [Anaerovibrio lipolyticus].	45.42	295	149	3	1	293	1	285	2e-75	244
rs:WP_038680770	methenyltetrahydrofolate cyclohydrolase [Rubrobacter radiotolerans].	47.40	289	141	5	3	290	2	280	2e-75	244
rs:WP_029511893	methenyltetrahydrofolate cyclohydrolase [Mesoplasma grammopterae].	46.37	289	146	3	5	293	3	282	2e-75	244
tr:A0A090FGK8_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.46	295	139	5	3	289	4	290	2e-75	244
rs:WP_014499621	methenyltetrahydrofolate cyclohydrolase [Buchnera aphidicola].	43.45	290	154	2	1	290	1	280	2e-75	244
rs:WP_007246878	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae group genomosp. 3].	47.28	294	147	3	1	294	1	286	2e-75	244
rs:WP_017698562	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	47.28	294	147	3	1	294	1	286	2e-75	244
rs:WP_017684352	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	46.94	294	148	3	1	294	1	286	2e-75	244
rs:WP_022061305	bifunctional protein FolD [Alistipes sp. CAG:53].	48.87	266	127	3	21	286	3	259	2e-75	243
tr:V6AT45_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.67	289	143	4	6	292	6	282	2e-75	244
rs:WP_024393140	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus suis].	46.88	288	143	3	5	292	3	280	2e-75	244
rs:WP_037599235	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus].	47.93	290	141	3	3	292	2	281	2e-75	244
rs:WP_029206074	methenyltetrahydrofolate cyclohydrolase [alpha proteobacterium SCGC AAA487-M09].	45.45	286	149	2	5	290	2	280	2e-75	244
rs:WP_027396244	5,10-methylene-tetrahydrofolate cyclohydrolase [Anaerovibrio lipolyticus].	45.89	292	146	3	1	290	1	282	2e-75	244
rs:WP_008542844	5,10-methylene-tetrahydrofolate dehydrogenase [Sutterella parvirubra].	44.71	293	147	4	1	293	1	278	2e-75	244
tr:S9S6L7_9RHOB	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.24	290	146	3	3	292	12	294	2e-75	245
tr:A0A0A8L0J7_9SACH	SubName: Full=WGS project CCBQ000000000 data, contig 00012 {ECO:0000313|EMBL:CDO92581.1};	45.89	292	151	3	5	293	36	323	2e-75	259
sp:FOLD2_FRAAA	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.52	292	151	3	1	292	1	281	2e-75	244
tr:M5RI69_9PLAN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.51	301	138	5	3	290	6	299	2e-75	244
tr:F7QYA2_9LACO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.59	296	153	4	1	296	3	287	2e-75	244
tr:B3T8P2_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.67	291	147	4	1	289	1	279	2e-75	244
rs:WP_035349623	methenyltetrahydrofolate cyclohydrolase [Edaphobacter aggregans].	43.05	302	150	4	5	290	7	302	2e-75	245
rs:WP_028420676	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. GXT6].	43.34	293	156	4	1	293	1	283	2e-75	244
rs:WP_022496003	MULTISPECIES: methylenetetrahydrofolate dehydrogenase [Streptococcus].	48.28	290	140	3	3	292	2	281	2e-75	244
rs:WP_007879708	5,10-methylene-tetrahydrofolate dehydrogenase [Ochrobactrum sp. CDB2].	47.80	295	146	4	3	293	2	292	2e-75	244
rs:WP_016169514	FolD protein [Lachnospiraceae bacterium 10-1].	50.35	284	130	4	3	286	2	274	2e-75	244
rs:WP_027405743	5,10-methylene-tetrahydrofolate cyclohydrolase [Anaerovibrio sp. RM50].	45.42	295	149	3	1	293	1	285	2e-75	244
rs:WP_037597576	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus salivarius].	48.28	290	140	3	3	292	2	281	2e-75	244
rs:WP_007142870	5,10-methylene-tetrahydrofolate dehydrogenase [Halobiforma lacisalsi].	46.71	289	152	2	1	289	27	313	2e-75	245
tr:A0A090DL68_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.14	297	141	5	1	289	1	289	2e-75	244
tr:B3TCS7_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.53	288	143	3	5	292	2	278	2e-75	244
rs:WP_037003216	methenyltetrahydrofolate cyclohydrolase [Pseudomonas pseudoalcaligenes].	47.42	291	145	4	1	291	1	283	2e-75	244
tr:A0A077WX77_9FUNG	SubName: Full=Putative C-1-tetrahydrofolate synthase,cytoplasmic {ECO:0000313|EMBL:CDS11829.1};	46.60	294	150	3	1	291	1	290	2e-75	259
rs:WP_010736000	FolD protein [Enterococcus mundtii].	47.57	288	140	4	3	290	2	278	2e-75	244
rs:WP_041003220	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. SOD10].	47.46	295	139	5	3	289	2	288	2e-75	244
rs:WP_000192105	tetrahydrofolate dehydrogenase [Streptococcus mitis].	46.55	290	145	3	4	293	3	282	2e-75	244
sp:FOLD_WIGBR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.31	286	155	2	1	286	1	276	2e-75	244
tr:J7TX79_STRSL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.28	290	140	3	3	292	12	291	2e-75	244
rs:WP_003382800	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	47.28	294	147	3	1	294	1	286	2e-75	244
rs:WP_022280314	MULTISPECIES: bifunctional protein FolD [Lactobacillus].	45.05	293	150	4	4	296	3	284	2e-75	244
rs:WP_024119021	5,10-methylene-tetrahydrofolate dehydrogenase [Thermus thermophilus].	45.67	289	141	4	1	289	1	273	2e-75	244
rs:WP_017773489	hypothetical protein [Burkholderia kururiensis].	48.26	288	141	4	2	289	3	282	2e-75	244
rs:WP_015587209	methylenetetrahydrofolate dehydrogenase [Mycoplasma putrefaciens].	46.10	282	143	3	5	286	3	275	2e-75	244
rs:WP_006014640	5,10-methylene-tetrahydrofolate dehydrogenase [Wolbachia pipientis].	44.93	296	153	4	5	297	4	292	2e-75	244
rs:WP_029207090	methenyltetrahydrofolate cyclohydrolase [alpha proteobacterium SCGC AAA280-B11].	45.10	286	150	2	5	290	2	280	2e-75	244
rs:WP_022673292	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingopyxis baekryungensis].	45.86	290	152	2	2	291	3	287	2e-75	244
rs:WP_004078965	FolD protein [Clostridium sp. ASF502].	47.89	284	137	4	3	286	2	274	2e-75	243
rs:WP_025126504	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. PH1b].	47.59	290	142	2	1	290	1	280	2e-75	244
rs:WP_007404995	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas].	44.86	292	152	3	1	291	1	284	2e-75	244
rs:WP_013038351	5,10-methylene-tetrahydrofolate dehydrogenase [Methanohalophilus mahii].	47.74	287	139	3	5	291	9	284	2e-75	244
rs:WP_006589168	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella birtlesii].	45.73	293	151	4	4	292	3	291	2e-75	244
rs:WP_038664268	methenyltetrahydrofolate cyclohydrolase [Sphingomonas taxi].	46.05	291	146	2	1	291	1	280	3e-75	244
rs:WP_014035315	methenyltetrahydrofolate cyclohydrolase [Mycoplasma putrefaciens].	45.74	282	144	3	5	286	3	275	3e-75	244
rs:WP_002720841	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodobacter sphaeroides].	47.26	292	147	2	1	292	1	285	3e-75	244
tr:W1PBB0_AMBTC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERN04315.1};	45.02	291	154	2	3	291	78	364	3e-75	246
sp:FOLD_CHLFF	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.64	289	154	3	5	292	2	285	3e-75	244
rs:WP_036122760	5,10-methylene-tetrahydrofolate cyclohydrolase [Lysinibacillus sphaericus].	46.42	293	146	3	1	293	1	282	3e-75	244
rs:WP_029241150	methenyltetrahydrofolate cyclohydrolase [Pseudomonas viridiflava].	47.40	289	144	3	3	291	4	284	3e-75	244
rs:WP_026912265	methenyltetrahydrofolate cyclohydrolase [Patulibacter minatonensis].	45.17	290	155	1	1	290	1	286	3e-75	244
rs:WP_041351524	methenyltetrahydrofolate cyclohydrolase [Neorickettsia risticii].	46.69	287	140	4	4	288	3	278	3e-75	244
rs:WP_027027360	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. URHA0056].	47.12	295	140	5	3	289	2	288	3e-75	244
rs:WP_026336262	methenyltetrahydrofolate cyclohydrolase [Acidobacteriaceae bacterium KBS 89].	43.23	303	150	5	4	290	5	301	3e-75	244
tr:A0A061M281_9BRAD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.08	287	141	3	5	291	42	320	3e-75	245
tr:T0U3G7_9STRE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.43	287	138	3	6	292	1	277	3e-75	243
gp:AP008231_759	FolD bifunctional protein [Synechococcus elongatus PCC 6301]	50.58	259	117	3	38	295	1	249	3e-75	243
rs:WP_015509505	tetrahydrofolate dehydrogenase [Enterococcus casseliflavus].	46.02	289	145	3	5	293	4	281	3e-75	243
rs:WP_023729060	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. LNJC405B00].	47.46	295	139	5	3	289	2	288	3e-75	244
rs:XP_010875218	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Esox lucius].	46.46	297	152	3	3	293	51	346	3e-75	246
rs:WP_022371341	bifunctional protein FolD [Firmicutes bacterium CAG:475].	46.53	288	143	4	4	290	2	279	3e-75	243
tr:X1NIY9_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S14791 {ECO:0000313|EMBL:GAI43538.1}; Flags: Fragment;	47.84	255	133	0	36	290	2	256	3e-75	243
rs:WP_038688770	methenyltetrahydrofolate cyclohydrolase [Stenotrophomonas rhizophila].	46.78	295	145	4	1	293	10	294	3e-75	244
rs:XP_006481278	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X3 [Citrus sinensis].	45.05	293	155	2	2	292	73	361	3e-75	246
rs:WP_014098818	5,10-methylene-tetrahydrofolate dehydrogenase [Chloracidobacterium thermophilum].	43.18	308	154	3	1	292	1	303	3e-75	244
tr:A0A0C7BNH0_9FUNG	SubName: Full=RMATCC62417_08417 protein {ECO:0000313|EMBL:CEG72944.1};	44.93	296	156	3	1	293	1	292	3e-75	258
rs:WP_006343126	5,10-methylene-tetrahydrofolate dehydrogenase [Chlamydia psittaci].	45.14	288	152	3	5	291	2	284	3e-75	243
rs:WP_010214581	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas sp. PAMC 26621].	47.75	289	140	3	1	289	1	278	3e-75	244
rs:WP_020370064	MULTISPECIES: tetrahydrofolate dehydrogenase [Chlamydia].	43.75	288	156	3	5	291	2	284	3e-75	243
tr:W3XY47_9STRE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.28	290	140	3	3	292	12	291	3e-75	244
rs:WP_007553157	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella sp. DB5-6].	46.76	293	142	7	4	289	3	288	3e-75	244
rs:WP_026896405	5,10-methylene-tetrahydrofolate cyclohydrolase [Clostridiales bacterium NK3B98].	46.78	295	141	5	1	293	1	281	3e-75	243
rs:WP_003041269	methylenetetrahydrofolate dehydrogenase [Sphingopyxis sp. MC1].	45.67	289	153	1	3	291	7	291	3e-75	244
rs:WP_036206115	methenyltetrahydrofolate cyclohydrolase [Lysobacter arseniciresistens].	47.44	293	142	3	2	292	8	290	3e-75	244
sp:FOLD_RHOSK	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.92	292	148	2	1	292	1	285	3e-75	244
rs:XP_006411084	hypothetical protein EUTSA_v10016863mg [Eutrema salsugineum].	44.98	289	153	2	5	291	65	349	3e-75	246
rs:WP_035807850	methenyltetrahydrofolate cyclohydrolase [Jeotgalicoccus sp. 13MG44_air].	44.83	290	147	5	1	290	1	277	3e-75	243
rs:WP_046001379	methenyltetrahydrofolate cyclohydrolase [Paracoccus sp. 361].	45.89	292	146	3	1	292	1	280	3e-75	244
rs:WP_008538653	5,10-methylene-tetrahydrofolate dehydrogenase [Megamonas funiformis].	44.71	293	149	4	1	290	1	283	3e-75	243
tr:A0A090PVB4_9FLAO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.35	222	108	0	70	291	4	225	3e-75	241
tr:C2LUV2_STRSL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.93	290	141	3	3	292	12	291	3e-75	244
rs:WP_022227954	bifunctional protein FolD [Megamonas funiformis CAG:377].	44.71	293	149	4	1	290	1	283	3e-75	243
rs:WP_022446068	bifunctional protein FolD [Faecalibacterium sp. CAG:74].	45.72	304	140	5	1	292	1	291	3e-75	244
rs:WP_043959076	methenyltetrahydrofolate cyclohydrolase [Lysobacter sp. A03].	48.12	293	140	3	2	292	9	291	4e-75	243
rs:WP_014746615	5,10-methylene-tetrahydrofolate dehydrogenase [Tistrella mobilis].	47.06	289	148	2	2	289	3	287	4e-75	244
tr:A0A078L5N4_9CHLA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576}; Flags: Precursor;	44.91	285	151	3	5	288	2	281	4e-75	243
rs:WP_025015875	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus sakei].	43.45	290	153	3	4	293	3	281	4e-75	243
rs:WP_018632463	hypothetical protein [Meganema perideroedes].	47.30	296	145	3	1	289	1	292	4e-75	244
rs:WP_023649252	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Pelagibacter ubique].	45.14	288	147	3	5	292	3	279	4e-75	243
sp:FOLD1_RHILO	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.44	295	142	5	3	289	2	288	4e-75	244
rs:WP_018999077	5,10-methylene-tetrahydrofolate dehydrogenase [Megamonas rupellensis].	44.71	293	149	4	1	290	1	283	4e-75	243
rs:WP_012985569	5,10-methylene-tetrahydrofolate dehydrogenase [Listeria seeligeri].	50.17	289	133	4	3	291	2	279	4e-75	243
rs:WP_046196148	methenyltetrahydrofolate cyclohydrolase [Aquamicrobium sp. SK-2].	47.20	286	143	3	6	291	7	284	4e-75	243
rs:WP_044392999	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae group genomosp. 3].	47.28	294	147	3	1	294	1	286	4e-75	244
rs:WP_026390719	hypothetical protein [Acholeplasma axanthum].	45.26	285	137	4	5	285	2	271	4e-75	243
rs:WP_008519300	5,10-methylene-tetrahydrofolate dehydrogenase [alpha proteobacterium IMCC14465].	46.55	290	150	2	1	289	1	286	4e-75	243
rs:WP_009490082	methylenetetrahydrofolate dehydrogenase [Catellicoccus marimammalium].	44.79	288	146	4	4	291	3	277	4e-75	243
rs:WP_018326277	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium giardinii].	47.62	294	144	5	3	291	2	290	4e-75	244
sp:FOLD_SYNJB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.17	290	153	2	1	290	1	284	4e-75	243
rs:WP_044559035	methenyltetrahydrofolate cyclohydrolase [Azospirillum sp. B4].	46.94	294	148	2	3	292	2	291	4e-75	244
rs:WP_029958603	methenyltetrahydrofolate cyclohydrolase [Ensifer sp. USDA 6670].	48.11	291	143	4	5	291	4	290	4e-75	244
rs:WP_028036059	methenyltetrahydrofolate cyclohydrolase [Candidatus Pelagibacter ubique].	44.79	288	148	3	5	292	3	279	4e-75	243
rs:WP_027826096	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus saerimneri].	47.57	288	140	3	5	292	4	280	4e-75	243
rs:WP_009561858	methylenetetrahydrofolate dehydrogenase [Rhodobacter sp. AKP1].	47.26	292	147	2	1	292	1	285	4e-75	243
rs:WP_002889033	tetrahydrofolate dehydrogenase [Streptococcus salivarius].	48.28	290	140	3	3	292	2	281	4e-75	243
rs:WP_013893719	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium opportunistum].	47.46	295	139	5	3	289	2	288	4e-75	243
rs:WP_013973143	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas putida group].	47.22	288	142	4	2	288	6	284	4e-75	244
rs:WP_028032416	methenyltetrahydrofolate cyclohydrolase [Chelativorans sp. J32].	47.65	298	139	6	3	292	2	290	4e-75	243
tr:F9HMQ3_STRMT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.55	290	145	3	4	293	24	303	4e-75	244
rs:WP_027239348	methenyltetrahydrofolate cyclohydrolase [Pseudophaeobacter arcticus].	46.42	293	152	2	1	292	1	289	4e-75	243
rs:WP_046921492	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus ruminis].	45.39	293	149	4	4	296	3	284	4e-75	243
rs:WP_046119776	methenyltetrahydrofolate cyclohydrolase [Sinorhizobium sp. PC2].	48.44	289	141	4	5	289	4	288	4e-75	243
rs:WP_031476986	5,10-methylene-tetrahydrofolate cyclohydrolase [Eubacterium desmolans].	46.55	290	143	5	1	290	1	278	4e-75	243
rs:WP_020043238	5,10-methylene-tetrahydrofolate dehydrogenase [Salipiger mucosus].	47.10	293	150	2	1	292	1	289	4e-75	243
rs:WP_017667087	hypothetical protein [Sandarakinorhabdus sp. AAP62].	48.81	295	140	4	1	290	1	289	4e-75	243
rs:WP_028717395	methenyltetrahydrofolate cyclohydrolase [Paracoccus sp. J39].	46.23	292	150	2	1	292	1	285	5e-75	243
rs:WP_024349403	methenyltetrahydrofolate cyclohydrolase [Aurantimonas coralicida].	47.52	303	138	7	3	292	4	298	5e-75	244
rs:WP_008329532	5,10-methylene-tetrahydrofolate dehydrogenase [Maritimibacter alkaliphilus].	47.26	292	149	2	1	292	1	287	5e-75	243
rs:XP_007032235	Amino acid dehydrogenase family protein isoform 4 [Theobroma cacao].	43.25	289	158	2	5	291	13	297	5e-75	243
rs:WP_036521057	methenyltetrahydrofolate cyclohydrolase [Nitrincola sp. A-D6].	46.53	288	146	3	6	293	11	290	5e-75	243
rs:WP_003529847	5,10-methylene-tetrahydrofolate dehydrogenase [Sinorhizobium meliloti].	48.45	291	142	4	5	291	4	290	5e-75	243
rs:XP_012310984	PREDICTED: cytoplasmic FMR1-interacting protein 2 [Aotus nancymaae].	49.15	293	142	3	5	291	722	1013	5e-75	261
rs:WP_005225772	tetrahydrofolate dehydrogenase [Enterococcus casseliflavus].	46.02	289	145	3	5	293	4	281	5e-75	243
rs:WP_008663957	methylenetetrahydrofolate dehydrogenase [Rhodopirellula europaea].	46.46	297	141	3	1	286	1	290	5e-75	243
rs:WP_005235351	MULTISPECIES: tetrahydrofolate dehydrogenase [Enterococcus].	46.02	289	145	3	5	293	4	281	5e-75	243
rs:WP_028301358	methenyltetrahydrofolate cyclohydrolase [Oceanospirillum beijerinckii].	47.44	293	144	4	3	293	2	286	5e-75	243
rs:WP_005617524	methylenetetrahydrofolate dehydrogenase [Pseudomonas avellanae].	47.28	294	147	3	1	294	1	286	5e-75	243
tr:S3FCX2_9BACL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.99	287	142	4	5	291	1	274	5e-75	243
rs:WP_026334127	5,10-methylene-tetrahydrofolate cyclohydrolase [Oxalobacteraceae bacterium AB_14].	46.58	292	145	4	1	292	1	281	5e-75	243
rs:WP_022373374	bifunctional protein FolD [Sutterella sp. CAG:397].	47.24	290	142	4	4	293	3	281	5e-75	243
sp:FOLD_LACSS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.45	290	153	3	4	293	2	280	5e-75	243
tr:W7TRX9_9STRA	SubName: Full=C-1-tetrahydrofolate cytoplasmic {ECO:0000313|EMBL:EWM26288.1};	44.22	303	152	2	4	293	11	309	5e-75	244
rs:WP_003152108	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas aeruginosa].	46.74	291	147	3	2	292	6	288	5e-75	243
rs:WP_038675584	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus salivarius].	48.28	290	140	3	3	292	2	281	5e-75	243
rs:WP_028163093	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium elkanii].	46.74	291	148	3	1	290	1	285	6e-75	243
rs:WP_013578792	5,10-methylene-tetrahydrofolate dehydrogenase [Granulicella tundricola].	43.42	304	150	5	2	289	3	300	6e-75	243
rs:WP_040887731	methenyltetrahydrofolate cyclohydrolase [Verrucomicrobium sp. 3C].	41.38	290	168	2	2	290	3	291	6e-75	243
tr:D4TKV7_9NOST	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.61	247	116	2	40	286	1	241	6e-75	241
tr:E3ZYZ6_LISSE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.17	289	133	4	3	291	2	279	6e-75	243
rs:WP_006906145	5,10-methylene-tetrahydrofolate dehydrogenase [Shuttleworthia satelles].	46.88	288	142	3	3	290	2	278	6e-75	243
tr:A0A0B0MNM0_GOSAR	SubName: Full=Bifunctional FolD {ECO:0000313|EMBL:KHG03703.1};	43.99	291	157	2	3	291	72	358	7e-75	245
rs:WP_014944997	5,10-methylene-tetrahydrofolate dehydrogenase [Chlamydia psittaci].	45.14	288	152	3	5	291	2	284	7e-75	243
rs:WP_040065032	methenyltetrahydrofolate cyclohydrolase [Pseudomonas batumici].	47.37	285	142	3	6	290	11	287	7e-75	243
rs:XP_010529466	PREDICTED: bifunctional protein FolD 1, mitochondrial [Tarenaya hassleriana].	44.83	290	154	2	5	292	63	348	7e-75	245
rs:WP_026613190	methenyltetrahydrofolate cyclohydrolase [Ensifer sp. TW10].	48.44	289	141	4	5	289	4	288	7e-75	243
rs:WP_015545610	tetrahydrofolate dehydrogenase [Mycoplasma mycoides].	43.26	282	151	3	5	286	3	275	7e-75	243
rs:WP_023766746	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. LNHC232B00].	47.46	295	139	5	3	289	2	288	7e-75	243
rs:WP_031832614	methenyltetrahydrofolate cyclohydrolase, partial [Staphylococcus aureus].	47.08	257	126	2	34	290	4	250	7e-75	241
rs:WP_012945727	5,10-methylene-tetrahydrofolate dehydrogenase [Haloterrigena turkmenica].	46.88	288	145	3	5	289	4	286	7e-75	243
rs:WP_023022489	MULTISPECIES: tetrahydrofolate dehydrogenase [Streptococcus].	46.71	289	144	3	5	293	4	282	7e-75	243
rs:WP_009379574	5,10-methylene-tetrahydrofolate dehydrogenase [Bilophila sp. 4_1_30].	46.37	289	153	1	3	289	2	290	7e-75	243
rs:WP_038144814	methenyltetrahydrofolate cyclohydrolase [Thioclava sp. 13D2W-2].	47.10	293	150	2	1	292	1	289	7e-75	243
rs:WP_010161483	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas sp. PAMC 26617].	47.08	291	143	3	1	291	1	280	7e-75	243
rs:WP_032928744	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium loti].	46.44	295	142	5	3	289	2	288	7e-75	243
rs:WP_020312726	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae].	46.94	294	148	3	1	294	1	286	8e-75	243
rs:WP_044050203	methenyltetrahydrofolate cyclohydrolase [Planktomarina temperata].	47.46	295	146	3	1	292	1	289	8e-75	243
rs:WP_040970452	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. ORS3324].	47.12	295	140	5	3	289	2	288	8e-75	243
tr:M1BHZ1_SOLTU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:PGSC0003DMT400045639};	44.22	294	158	2	2	293	25	314	8e-75	243
tr:A0A090BP62_KLUMA	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:BAP73607.1};	45.55	292	152	3	5	293	38	325	8e-75	258
rs:WP_010303616	methenyltetrahydrofolate cyclohydrolase [Synechococcus sp. CB0101].	45.91	281	147	2	6	286	5	280	8e-75	243
rs:WP_022324929	bifunctional protein FolD [Alistipes sp. CAG:435].	47.89	284	135	4	6	286	3	276	9e-75	242
rs:WP_012531348	5,10-methylene-tetrahydrofolate dehydrogenase [Geobacter bemidjiensis].	46.23	292	149	4	4	293	2	287	9e-75	243
rs:WP_029453184	methenyltetrahydrofolate cyclohydrolase [Clostridium algidicarnis].	42.81	292	156	2	3	294	2	282	9e-75	242
rs:WP_023177169	tetrahydrofolate dehydrogenase [Carnobacterium sp. WN1359].	45.02	291	149	3	1	291	1	280	9e-75	242
sp:FOLD2_DEIGD	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.52	290	148	4	1	290	1	280	9e-75	242
tr:W0TEY9_KLUMA	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:BAO42207.1};	45.55	292	152	3	5	293	38	325	9e-75	257
sp:FOLD_HERAR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.74	291	144	3	1	291	1	280	9e-75	242
rs:WP_028099662	methenyltetrahydrofolate cyclohydrolase [Dongia sp. URHE0060].	48.25	286	141	3	4	289	6	284	9e-75	243
rs:WP_044886147	5,10-methylene-tetrahydrofolate cyclohydrolase [Frankia sp. CpI1-S].	44.18	292	152	3	1	292	1	281	9e-75	242
rs:WP_023847957	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodobacteraceae bacterium PD-2].	44.67	291	154	2	1	291	1	284	1e-74	243
sp:FOLD_STRS2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.53	288	144	3	5	292	3	280	1e-74	242
rs:WP_001632268	methylenetetrahydrofolate dehydrogenase, partial [Salmonella enterica].	50.00	262	121	3	1	262	1	252	1e-74	241
rs:WP_014529027	5,10-methylene-tetrahydrofolate dehydrogenase [Sinorhizobium meliloti].	48.45	291	142	4	5	291	4	290	1e-74	243
rs:WP_023854573	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Pelagibacter ubique].	45.14	288	147	3	5	292	3	279	1e-74	242
rs:WP_037553150	methenyltetrahydrofolate cyclohydrolase [Sphingopyxis sp. LC363].	44.48	290	157	1	2	291	7	292	1e-74	243
rs:WP_005771251	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas syringae group].	47.28	294	147	3	1	294	1	286	1e-74	243
sp:FOLD_LYSSC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.08	293	147	3	1	293	1	282	1e-74	242
rs:XP_012152844	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Megachile rotundata].	46.62	296	149	4	3	292	28	320	1e-74	244
rs:WP_029386734	methenyltetrahydrofolate cyclohydrolase [Streptomyces cyaneogriseus].	43.00	293	157	4	1	293	1	283	1e-74	242
sp:FOLD_KORVE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.12	306	149	4	1	290	1	300	1e-74	243
rs:WP_023386565	5,10-methylene-tetrahydrofolate dehydrogenase [Anaplasma marginale].	45.52	290	150	4	4	292	3	285	1e-74	243
rs:WP_020024184	hypothetical protein [gamma proteobacterium SCGC AAA076-D02].	48.07	285	134	3	4	288	2	272	1e-74	242
rs:WP_017186567	hypothetical protein [Alkalibacillus haloalkaliphilus].	46.05	291	146	4	1	291	1	280	1e-74	242
rs:WP_016264851	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus sakei].	43.45	290	153	3	4	293	2	280	1e-74	242
rs:WP_018167749	tetrahydrofolate dehydrogenase [Streptococcus minor].	46.53	288	144	3	5	292	3	280	1e-74	242
rs:WP_028879986	methenyltetrahydrofolate cyclohydrolase [Terasakiella pusilla].	47.06	289	145	4	3	289	4	286	1e-74	242
tr:A0A0A1NBY8_9FUNG	SubName: Full=Putative FTHFS-domain-containing protein {ECO:0000313|EMBL:CEI89253.1};	44.93	296	156	3	1	293	1	292	1e-74	257
rs:WP_005029330	5,10-methylene-tetrahydrofolate dehydrogenase [Bilophila wadsworthia].	46.02	289	154	1	3	289	2	290	1e-74	242
rs:WP_043305676	methenyltetrahydrofolate cyclohydrolase [Pseudomonas viridiflava].	47.06	289	145	3	3	291	4	284	1e-74	243
rs:WP_027673828	methenyltetrahydrofolate cyclohydrolase [Agrobacterium larrymoorei].	46.92	292	147	4	5	292	4	291	1e-74	242
sp:FOLD_PROM4	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.39	287	144	2	3	286	2	284	1e-74	243
sp:FOLD_MYCMS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.26	282	151	3	5	286	3	275	1e-74	242
rs:WP_034811708	methenyltetrahydrofolate cyclohydrolase, partial [Hyphomonas sp. L-53-1-40].	48.63	292	138	5	1	289	1	283	1e-74	242
tr:F8LK65_STREH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.08	287	139	3	6	292	1	277	1e-74	242
rs:WP_014092743	5,10-methylene-tetrahydrofolate dehydrogenase [Listeria ivanovii].	50.17	289	133	4	3	291	2	279	1e-74	242
rs:WP_026879348	methenyltetrahydrofolate cyclohydrolase [Ignatzschineria larvae].	46.69	287	145	4	3	288	2	281	1e-74	242
sp:FOLD2_PSESM	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.28	294	147	3	1	294	1	286	1e-74	242
rs:WP_024087352	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas monteilii].	47.22	288	142	4	2	288	6	284	1e-74	243
rs:WP_022565243	bifunctional protein FolD [Blattabacterium sp. (Nauphoeta cinerea)].	41.03	290	163	3	1	289	1	283	1e-74	242
rs:WP_025279919	5,10-methylene-tetrahydrofolate cyclohydrolase [Listeria ivanovii].	50.17	289	133	4	3	291	2	279	1e-74	242
tr:F8HER1_STRE5	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.08	287	139	3	6	292	1	277	1e-74	242
rs:WP_035516273	methenyltetrahydrofolate cyclohydrolase [Pseudohaliea rubra].	44.56	294	155	4	1	292	1	288	1e-74	242
rs:WP_009809340	5,10-methylene-tetrahydrofolate dehydrogenase [Roseobacter sp. MED193].	46.08	293	153	2	1	292	1	289	1e-74	242
sp:FOLD_FUSNN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.64	287	144	4	5	290	2	277	1e-74	242
tr:S0DDE6_9ZZZZ	SubName: Full=Putative methylene-tetrahydrofolate dehydrogenase cyclohydrolase {ECO:0000313|EMBL:CCO21003.1};	45.95	296	148	4	1	296	2	285	1e-74	242
rs:WP_046784197	methenyltetrahydrofolate cyclohydrolase [Mycoplasma capricolum].	44.29	289	152	3	5	293	3	282	1e-74	242
rs:WP_005902337	bifunctional protein FolD [Fusobacterium nucleatum].	45.64	287	144	4	5	290	2	277	1e-74	242
rs:WP_044958833	methenyltetrahydrofolate cyclohydrolase [Shuttleworthia sp. MSX8B].	46.53	288	143	3	3	290	2	278	1e-74	242
rs:WP_006726392	5,10-methylene-tetrahydrofolate dehydrogenase [Agrobacterium albertimagni].	47.08	291	146	4	5	291	4	290	1e-74	242
rs:WP_029597324	bifunctional protein FolD [Fusobacterium nucleatum].	45.64	287	144	4	5	290	2	277	1e-74	242
rs:WP_038409927	methenyltetrahydrofolate cyclohydrolase [Pseudomonas putida].	47.22	288	142	4	2	288	6	284	1e-74	242
rs:WP_037212064	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. YR295].	44.52	292	154	3	1	292	2	285	1e-74	242
rs:WP_016610296	tetrahydrofolate dehydrogenase [Enterococcus casseliflavus].	45.67	289	146	3	5	293	4	281	1e-74	242
rs:WP_035932362	hypothetical protein [Fusobacterium necrophorum].	43.06	281	150	3	4	284	2	272	1e-74	242
rs:WP_014629516	5,10-methylene-tetrahydrofolate dehydrogenase [Thermus thermophilus].	45.67	289	141	4	1	289	1	273	2e-74	241
rs:WP_042685132	5,10-methylene-tetrahydrofolate cyclohydrolase [Methermicoccus shengliensis].	46.34	287	141	4	4	289	14	288	2e-74	242
rs:WP_036358118	methenyltetrahydrofolate cyclohydrolase [Microvirga sp. BSC39].	45.52	290	152	3	1	289	1	285	2e-74	242
rs:WP_009190246	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. e14].	43.34	293	156	4	1	293	1	283	2e-74	241
rs:WP_008451566	5,10-methylene-tetrahydrofolate dehydrogenase [Janthinobacterium sp. HH01].	45.55	292	148	3	1	292	1	281	2e-74	241
rs:WP_021777468	domain containing protein [alpha proteobacterium RS24].	46.55	290	150	2	1	289	1	286	2e-74	242
rs:WP_029031493	methenyltetrahydrofolate cyclohydrolase [Salinarimonas rosea].	47.08	291	148	3	1	290	1	286	2e-74	242
rs:WP_045749895	methenyltetrahydrofolate cyclohydrolase [Acholeplasma oculi].	44.29	280	141	3	5	284	2	266	2e-74	241
rs:WP_025994691	methenyltetrahydrofolate cyclohydrolase [Pseudomonas viridiflava].	47.40	289	144	3	3	291	4	284	2e-74	242
rs:WP_013695010	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Pelagibacter sp. IMCC9063].	45.64	287	148	3	5	291	2	280	2e-74	241
rs:WP_023431405	methylenetetrahydrofolate dehydrogenase [Lutibaculum baratangense].	46.05	291	151	2	1	291	1	285	2e-74	242
rs:WP_019960514	hypothetical protein [Woodsholea maritima].	45.86	290	152	2	3	291	12	297	2e-74	242
rs:WP_029065055	methenyltetrahydrofolate cyclohydrolase [Labrenzia sp. DG1229].	47.12	295	146	5	2	291	3	292	2e-74	242
rs:WP_009572632	5,10-methylene-tetrahydrofolate dehydrogenase [Celeribacter baekdonensis].	45.12	297	155	3	1	296	1	290	2e-74	242
rs:WP_018480578	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium leguminosarum].	47.60	292	143	5	5	291	3	289	2e-74	242
rs:WP_018564921	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	43.00	293	157	4	1	293	1	283	2e-74	241
rs:WP_008184692	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodobacteraceae bacterium HTCC2150].	45.89	292	154	1	1	292	1	288	2e-74	242
rs:WP_010747994	FolD protein [Enterococcus casseliflavus].	46.02	289	145	3	5	293	4	281	2e-74	241
sp:FOLD_THET8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.33	289	142	4	1	289	1	273	2e-74	241
rs:WP_013384886	5,10-methylene-tetrahydrofolate dehydrogenase [Ketogulonicigenium vulgare].	48.61	288	142	3	1	288	1	282	2e-74	242
rs:WP_047007641	methenyltetrahydrofolate cyclohydrolase, partial [Erythrobacter gangjinensis].	47.39	287	144	3	3	289	2	281	2e-74	241
tr:A0A0C5NAR1_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJQ01626.1};	46.23	292	150	3	5	293	37	324	2e-74	256
sp:FOLD_BLOFL	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.44	288	150	2	1	288	1	278	2e-74	242
rs:WP_020495785	hypothetical protein [Sciscionella marina].	44.48	290	150	2	1	290	1	279	2e-74	241
rs:WP_046915465	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces stelliscabiei].	43.43	297	156	3	1	297	1	285	2e-74	241
rs:WP_009823260	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas sp. SKA58].	47.20	286	147	1	4	289	5	286	2e-74	242
rs:WP_008308047	5,10-methylene-tetrahydrofolate dehydrogenase [Leptolyngbya sp. PCC 6406].	45.58	283	148	2	4	286	3	279	2e-74	242
tr:E7Q0P0_YEASB	SubName: Full=Mis1p {ECO:0000313|EMBL:EGA59850.1};	46.23	292	150	3	5	293	37	324	2e-74	256
rs:WP_014338947	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas fluorescens].	47.55	286	142	3	4	289	5	282	2e-74	242
rs:WP_010859746	5,10-methylene-tetrahydrofolate dehydrogenase [Lysinibacillus sphaericus].	46.08	293	147	4	1	293	1	282	2e-74	241
rs:WP_038748803	methenyltetrahydrofolate cyclohydrolase [Burkholderia pseudomallei].	49.65	286	133	4	1	286	1	275	2e-74	241
rs:WP_014428565	5,10-methylene-tetrahydrofolate dehydrogenase [Rubrivivax gelatinosus].	45.55	292	145	4	1	292	1	278	2e-74	241
rs:WP_020021869	hypothetical protein [alpha proteobacterium SCGC AAA536-G10].	46.23	292	150	2	4	292	6	293	2e-74	242
rs:WP_046904332	methenyltetrahydrofolate cyclohydrolase [Altererythrobacter atlanticus].	47.60	292	144	4	3	293	2	285	2e-74	242
rs:WP_027128834	5,10-methylene-tetrahydrofolate cyclohydrolase [Fusobacterium perfoetens].	45.14	288	145	4	5	290	3	279	2e-74	241
rs:WP_017548371	hypothetical protein [Salinicoccus carnicancri].	44.48	290	148	4	1	290	1	277	2e-74	241
rs:WP_013676971	methenyltetrahydrofolate cyclohydrolase [Pseudonocardia dioxanivorans].	45.86	290	142	4	1	290	1	275	2e-74	241
rs:WP_036432227	methenyltetrahydrofolate cyclohydrolase [Mycoplasma capricolum].	44.29	289	152	3	5	293	3	282	2e-74	241
rs:WP_023776556	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. LNHC221B00].	47.12	295	140	5	3	289	2	288	2e-74	242
tr:A0A0C5PSS9_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJQ15378.1};	46.23	292	150	3	5	293	37	324	2e-74	256
rs:WP_024361178	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Lysinibacillus].	46.76	293	145	4	1	293	1	282	2e-74	241
tr:K7IPP6_NASVI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:NV11033-PA};	47.28	294	147	3	3	290	28	319	2e-74	253
tr:E0P1Q9_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.95	292	139	4	1	290	1	281	2e-74	241
rs:WP_017271293	5,10-methylene-tetrahydrofolate dehydrogenase [Sinorhizobium meliloti].	48.45	291	142	4	5	291	4	290	2e-74	242
rs:WP_023497596	methenyltetrahydrofolate cyclohydrolase [uncultured archaeon A07HR67].	48.10	289	148	2	3	291	2	288	2e-74	242
tr:G5PZH4_SALMO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.00	266	123	3	1	266	1	256	2e-74	241
rs:WP_036193729	methenyltetrahydrofolate cyclohydrolase [Lysobacter concretionis].	48.08	287	137	3	2	286	9	285	2e-74	242
rs:WP_006586931	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus jensenii].	45.52	290	146	4	3	292	2	279	2e-74	241
tr:W0K057_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.26	285	154	2	5	289	4	286	2e-74	241
sp:FOLD_SOLUE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.09	304	152	3	4	291	3	301	2e-74	242
rs:WP_033078845	methenyltetrahydrofolate cyclohydrolase [Thalassotalea sp. ND16A].	47.57	288	142	4	6	291	3	283	2e-74	241
tr:A0A0C5PHJ5_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJQ15002.1};	46.23	292	150	3	5	293	37	324	2e-74	256
rs:WP_044152242	methenyltetrahydrofolate cyclohydrolase [Anaplasma phagocytophilum].	46.37	289	147	3	5	292	8	289	2e-74	242
rs:WP_024863505	methenyltetrahydrofolate cyclohydrolase [Entomoplasma somnilux].	45.74	282	144	2	5	286	3	275	2e-74	241
rs:WP_012526625	5,10-methylene-tetrahydrofolate dehydrogenase [Anaeromyxobacter sp. K].	49.13	289	135	4	5	292	3	280	2e-74	241
rs:WP_043358574	methenyltetrahydrofolate cyclohydrolase [Belnapia sp. F-4-1].	47.40	289	138	3	1	289	1	275	2e-74	241
rs:WP_012633817	5,10-methylene-tetrahydrofolate dehydrogenase [Anaeromyxobacter dehalogenans].	48.62	290	137	4	5	293	3	281	2e-74	241
rs:WP_035527593	methenyltetrahydrofolate cyclohydrolase [Hoeflea sp. BAL378].	48.31	296	141	6	3	292	2	291	2e-74	242
rs:WP_006702182	5,10-methylene-tetrahydrofolate dehydrogenase [Facklamia ignava].	47.06	289	142	3	1	289	1	278	2e-74	241
rs:XP_010666362	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X1 [Beta vulgaris subsp. vulgaris].	42.32	293	163	2	1	291	70	358	2e-74	244
rs:XP_005764935	methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase [Emiliania huxleyi CCMP1516].	45.92	294	152	2	3	293	59	348	2e-74	243
rs:WP_029499111	5,10-methylene-tetrahydrofolate cyclohydrolase [Kurthia huakuii].	47.10	293	144	4	1	293	1	282	3e-74	241
rs:WP_015270834	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas putida].	46.88	288	143	4	2	288	6	284	3e-74	242
tr:S2JWD4_MUCC1	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:EPB92747.1};	47.60	292	146	3	3	291	4	291	3e-74	256
tr:X1K914_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C02152 {ECO:0000313|EMBL:GAH90125.1};	46.94	294	148	4	3	292	2	291	3e-74	241
rs:WP_024685136	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.18	284	142	3	3	286	4	279	3e-74	241
rs:WP_009493527	5,10-methylene-tetrahydrofolate dehydrogenase [Microvirga lotononidis].	45.52	290	152	3	1	289	1	285	3e-74	241
rs:WP_024706150	methenyltetrahydrofolate cyclohydrolase [Martelella sp. AD-3].	46.23	292	152	2	1	291	1	288	3e-74	241
rs:WP_026134879	5,10-methylene-tetrahydrofolate cyclohydrolase [Scytonema hofmanni].	43.15	292	160	2	2	293	5	290	3e-74	241
rs:XP_012478246	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X2 [Gossypium raimondii].	44.33	291	156	2	3	291	76	362	3e-74	244
rs:WP_043271773	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. AAC].	48.44	289	141	4	2	290	6	286	3e-74	241
rs:WP_028966668	methenyltetrahydrofolate cyclohydrolase [Sphingomonas phyllosphaerae].	46.74	291	143	3	1	291	1	279	3e-74	241
rs:WP_014961189	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Leptospirillum].	46.71	289	142	4	1	288	1	278	3e-74	241
tr:A0A0C5NX60_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJQ09271.1};	46.23	292	150	3	5	293	37	324	3e-74	256
rs:WP_018185251	hypothetical protein [Kaistia granuli].	47.12	295	146	5	3	292	13	302	3e-74	242
sp:FOLD1_PARDP	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.89	292	151	2	1	292	1	285	3e-74	241
tr:A0A0C5MUB8_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJP99703.1};	46.23	292	150	3	5	293	37	324	3e-74	256
tr:A0A0C5N2L2_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJP98539.1};	46.23	292	150	3	5	293	37	324	3e-74	256
tr:A0A087RNH3_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.02	291	146	5	1	289	1	279	3e-74	241
rs:WP_020915417	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Profftella armatura].	44.86	292	150	3	1	292	1	281	3e-74	241
rs:WP_007530154	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium mesoamericanum].	47.26	292	146	4	5	292	4	291	3e-74	241
rs:WP_008975617	5,10-methylene-tetrahydrofolate dehydrogenase [Lachnospiraceae bacterium 6_1_37FAA].	46.88	288	142	3	4	291	3	279	3e-74	241
gpu:CP011097_634	5,10-methylene-tetrahydrofolate cyclohydrolase [Thaumarchaeota archaeon SAT1]	44.90	294	148	4	1	292	1	282	3e-74	241
rs:XP_008244205	PREDICTED: bifunctional protein FolD 1, mitochondrial [Prunus mume].	44.18	292	157	2	2	291	75	362	3e-74	244
tr:V4NEH9_9CAUL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.15	299	149	5	3	296	13	304	3e-74	242
tr:A0A0C5LS05_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJP85903.1};	46.23	292	150	3	5	293	37	324	3e-74	256
tr:A0A0C5P8K3_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJQ08498.1};	46.23	292	150	3	5	293	37	324	3e-74	256
tr:A0A0C5MAH6_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJP88551.1};	46.23	292	150	3	5	293	37	324	3e-74	256
rs:WP_006035727	methenyltetrahydrofolate cyclohydrolase [Rickettsiella grylli].	42.07	290	158	2	1	290	1	280	3e-74	241
rs:WP_031024587	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL WC-3725].	43.49	292	155	4	1	292	1	282	3e-74	241
tr:A0A0C5PEE9_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJQ15766.1};	46.23	292	150	3	5	293	37	324	3e-74	256
tr:A0A0C5M673_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJP91178.1};	46.23	292	150	3	5	293	37	324	3e-74	256
tr:A0A0C5M269_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJP86280.1};	46.23	292	150	3	5	293	37	324	3e-74	256
rs:WP_008179891	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus sp. B14905].	46.08	293	147	3	1	293	1	282	3e-74	241
rs:WP_027835340	methenyltetrahydrofolate cyclohydrolase [Maritalea myrionectae].	46.18	288	148	4	1	286	1	283	3e-74	241
sp:C1TM_YEAST	RecName: Full=C-1-tetrahydrofolate synthase, mitochondrial; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3; Flags: Precursor;	46.23	292	150	3	5	293	37	324	3e-74	256
tr:S2JSB2_MUCC1	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:EPB85578.1};	46.60	294	150	3	1	291	1	290	3e-74	256
tr:A0A0C5NUA0_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJQ08111.1};	46.23	292	150	3	5	293	37	324	3e-74	256
tr:A0A0C5LSQ0_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJP82449.1};	46.23	292	150	3	5	293	37	324	3e-74	256
tr:A0A0C5P1N2_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJQ10430.1};	46.23	292	150	3	5	293	37	324	3e-74	256
tr:A0A0C5N2P3_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJP98925.1};	46.23	292	150	3	5	293	37	324	3e-74	256
rs:XP_001642347	hypothetical protein Kpol_243p3 [Vanderwaltozyma polyspora DSM 70294].	45.95	296	153	3	2	294	32	323	3e-74	256
tr:A0A0C5M9I1_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJP88171.1};	46.23	292	150	3	5	293	37	324	3e-74	256
rs:WP_007477860	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella melophagi].	47.80	295	140	7	5	292	4	291	3e-74	241
rs:WP_019806339	5,10-methylene-tetrahydrofolate dehydrogenase [Osedax symbiont Rs1].	46.88	288	143	4	6	291	5	284	3e-74	241
tr:A0A068S5R5_9FUNG	SubName: Full=Fthfs-domain-containing protein {ECO:0000313|EMBL:CDH57723.1};	45.92	294	152	3	1	291	1	290	3e-74	255
tr:E7QBW9_YEASZ	SubName: Full=Mis1p {ECO:0000313|EMBL:EGA87859.1};	46.23	292	150	3	5	293	37	324	3e-74	256
tr:A0A0C5PA15_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJQ14241.1};	46.23	292	150	3	5	293	37	324	3e-74	256
rs:WP_025338666	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. FGI182].	46.85	286	142	4	4	288	8	284	3e-74	241
rs:WP_006451188	methenyltetrahydrofolate cyclohydrolase [Xanthomonas gardneri].	47.22	288	140	3	4	289	13	290	3e-74	241
rs:WP_040581008	methenyltetrahydrofolate cyclohydrolase [Methyloferula stellata].	47.49	299	142	5	3	291	8	301	4e-74	241
tr:A0A0C5M159_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJP85146.1};	46.23	292	150	3	5	293	37	324	4e-74	256
rs:WP_038131974	methenyltetrahydrofolate cyclohydrolase [Thioclava sp. DT23-4].	46.08	293	153	2	1	292	1	289	4e-74	241
rs:WP_008228106	5,10-methylene-tetrahydrofolate dehydrogenase [Roseobacter sp. GAI101].	47.78	293	148	2	1	292	1	289	4e-74	241
rs:WP_004860669	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella taylorii].	45.14	288	150	4	5	288	4	287	4e-74	241
rs:WP_020708054	hypothetical protein [Acidobacteriaceae bacterium KBS 83].	41.83	306	156	4	1	290	1	300	4e-74	241
rs:WP_013703621	5,10-methylene-tetrahydrofolate dehydrogenase [Marinithermus hydrothermalis].	45.67	289	141	5	3	291	2	274	4e-74	240
rs:WP_028749882	methenyltetrahydrofolate cyclohydrolase [Rhizobium mesoamericanum].	47.26	292	146	4	5	292	4	291	4e-74	241
tr:M1BHZ0_SOLTU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:PGSC0003DMT400045638};	44.22	294	158	2	2	293	56	345	4e-74	243
rs:WP_024694066	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.18	284	142	3	3	286	4	279	4e-74	241
rs:WP_025116083	5,10-methylene-tetrahydrofolate cyclohydrolase [Lysinibacillus fusiformis].	45.73	293	148	3	1	293	1	282	4e-74	241
rs:XP_012152776	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Megachile rotundata].	46.62	296	149	4	3	292	45	337	4e-74	243
rs:WP_033292476	5,10-methylene-tetrahydrofolate cyclohydrolase [Amycolatopsis jejuensis].	45.67	289	146	2	1	289	1	278	4e-74	241
rs:WP_045982846	methenyltetrahydrofolate cyclohydrolase [Paracoccus sp. S4493].	45.55	292	147	3	1	292	1	280	4e-74	241
rs:WP_023515738	bifunctional protein FolD 2 [Shinella sp. DD12].	46.05	291	149	4	5	291	4	290	4e-74	241
rs:WP_019054018	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium xenophagum].	44.10	288	154	2	4	291	3	283	4e-74	241
rs:WP_021799281	methylenetetrahydrofolate dehydrogenase [Anaplasma phagocytophilum].	46.37	289	147	3	5	292	8	289	4e-74	241
rs:WP_022486180	bifunctional protein FolD [Fusobacterium sp. CAG:815].	46.32	285	137	5	3	286	2	271	4e-74	240
rs:WP_010759633	FolD protein [Enterococcus pallens].	46.53	288	143	4	5	292	4	280	4e-74	240
rs:XP_007032233	Amino acid dehydrogenase family protein isoform 1 [Theobroma cacao].	43.25	289	158	2	5	291	81	365	4e-74	243
rs:XP_008454370	PREDICTED: bifunctional protein FolD 2 isoform X2 [Cucumis melo].	47.35	264	133	2	32	293	15	274	4e-74	240
rs:WP_035547199	methenyltetrahydrofolate cyclohydrolase [Hyphomonas atlantica].	48.97	292	137	5	1	289	1	283	5e-74	241
tr:A0A0D6QNV7_9DELT	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:GAO04502.1};	48.96	288	135	4	5	291	3	279	5e-74	240
rs:WP_029571777	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas syringae].	48.64	257	122	2	34	290	2	248	5e-74	239
rs:WP_003698486	tetrahydrofolate dehydrogenase [Lactobacillus ruminis].	44.71	293	151	4	4	296	3	284	5e-74	240
rs:WP_009827885	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodobacteraceae bacterium HTCC2083].	47.26	292	147	2	1	292	1	285	5e-74	241
rs:WP_036083253	methenyltetrahydrofolate cyclohydrolase [Leptospirillum ferriphilum].	46.37	289	143	4	1	288	1	278	5e-74	241
rs:WP_042640920	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. ORS3359].	47.12	295	140	5	3	289	2	288	5e-74	241
rs:WP_008593696	5,10-methylene-tetrahydrofolate dehydrogenase [Nitratireductor pacificus].	46.60	294	148	5	3	292	2	290	5e-74	241
rs:XP_007557970	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X4 [Poecilia formosa].	47.49	299	150	3	2	294	5	302	5e-74	241
sp:FOLD_MYCCT	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.94	289	153	3	5	293	3	282	5e-74	240
rs:WP_021816315	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus fermentum].	46.23	292	143	4	4	292	3	283	5e-74	240
rs:WP_039652840	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	42.66	293	158	4	1	293	1	283	5e-74	240
rs:WP_035029237	5,10-methylene-tetrahydrofolate cyclohydrolase [Carnobacterium mobile].	43.34	293	155	3	1	293	1	282	5e-74	240
rs:WP_016491374	methylenetetrahydrofolate dehydrogenase [Pseudomonas resinovorans].	48.25	286	140	3	5	290	9	286	5e-74	241
rs:WP_037860979	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-340].	43.00	293	157	5	1	293	1	283	6e-74	240
rs:XP_009590695	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X2 [Nicotiana tomentosiformis].	46.67	270	138	2	27	294	2	267	6e-74	239
rs:WP_012706891	5,10-methylene-tetrahydrofolate dehydrogenase [Sinorhizobium fredii].	48.29	292	141	5	5	291	4	290	6e-74	241
rs:WP_037351933	methenyltetrahydrofolate cyclohydrolase [Anaplasma marginale].	44.83	290	152	4	4	292	3	285	6e-74	241
rs:XP_010935085	PREDICTED: bifunctional protein FolD 4, chloroplastic-like isoform X1 [Elaeis guineensis].	45.00	300	151	3	2	291	70	365	6e-74	243
rs:WP_005584344	methylenetetrahydrofolate dehydrogenase [Clostridium ultunense].	46.37	289	144	4	1	289	1	278	6e-74	240
rs:WP_046052995	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	47.55	286	142	3	4	289	5	282	6e-74	241
tr:A0A085VKN2_PSESX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.67	285	144	3	2	286	3	279	6e-74	241
rs:XP_006356966	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X2 [Solanum tuberosum].	44.22	294	158	2	2	293	74	363	6e-74	243
rs:WP_030389149	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-241].	43.15	292	156	4	1	292	1	282	6e-74	240
rs:WP_009622558	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. M1].	48.44	289	141	4	2	290	6	286	6e-74	240
rs:WP_010700838	methylenetetrahydrofolate dehydrogenase [Bartonella bovis].	48.14	295	139	7	5	292	4	291	6e-74	241
rs:WP_012881001	5,10-methylene-tetrahydrofolate dehydrogenase [Anaplasma centrale].	45.17	290	151	4	4	292	3	285	6e-74	241
rs:WP_007205659	5,10-methylene-tetrahydrofolate dehydrogenase [Loktanella vestfoldensis].	46.76	293	148	3	1	292	1	286	6e-74	240
rs:WP_009261942	5,10-methylene-tetrahydrofolate dehydrogenase [Coprococcus sp. HPP0074].	46.88	288	142	3	4	291	3	279	6e-74	240
rs:XP_003682229	hypothetical protein TDEL_0F02070 [Torulaspora delbrueckii].	44.41	295	157	3	6	297	26	316	6e-74	255
rs:WP_033919393	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. 37zxx].	47.77	291	141	2	1	291	1	280	6e-74	240
sp:FOLD_BUCAP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.92	291	159	2	1	291	1	281	6e-74	240
rs:WP_027045178	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. URHC0008].	46.74	291	147	4	3	289	2	288	6e-74	241
rs:WP_004231154	5,10-methylene-tetrahydrofolate dehydrogenase [Lysinibacillus fusiformis].	46.42	293	146	3	1	293	1	282	6e-74	240
tr:A0A0A7UYU4_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.92	294	145	5	1	292	1	282	6e-74	240
rs:WP_013933656	5,10-methylene-tetrahydrofolate dehydrogenase [Zymomonas mobilis].	45.55	292	151	2	3	290	4	291	7e-74	241
rs:WP_034538452	5,10-methylene-tetrahydrofolate cyclohydrolase [Carnobacterium inhibens].	44.67	291	150	3	1	291	1	280	7e-74	240
tr:A0A0C9MCN2_9FUNG	SubName: Full=DNA, scaffold: scf_mam1_v10001, strain NBRC 6742, whole genome shotgun sequence {ECO:0000313|EMBL:GAN00692.1};	47.60	292	146	3	3	291	4	291	7e-74	254
rs:WP_043870949	methenyltetrahydrofolate cyclohydrolase [Celeribacter indicus].	46.58	292	147	4	1	291	1	284	7e-74	240
rs:WP_014517788	5,10-methylene-tetrahydrofolate dehydrogenase [Chlamydia pneumoniae].	45.04	282	149	3	5	285	2	278	7e-74	240
rs:WP_045998299	methenyltetrahydrofolate cyclohydrolase [Loktanella sp. S4079].	45.89	292	152	2	1	292	1	286	7e-74	240
sp:FOLD_LACF3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.23	292	143	4	4	292	3	283	7e-74	240
tr:A0A0B7BB58_9EUPU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CEK89506.1};	45.97	298	149	6	3	294	2	293	7e-74	241
rs:WP_042857328	methenyltetrahydrofolate cyclohydrolase [Pseudomonas aeruginosa].	46.74	291	147	4	1	291	1	283	7e-74	240
rs:WP_010703383	methylenetetrahydrofolate dehydrogenase [Bartonella schoenbuchensis].	47.80	295	140	7	5	292	4	291	7e-74	240
tr:D3UEH7_YEAS8	SubName: Full=Chromosome II, EC1118_1B15 genomic scaffold, whole genome shotgun sequence {ECO:0000313|EMBL:CBK39157.1};	45.89	292	151	3	5	293	37	324	7e-74	255
tr:A0A0C5LY28_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJP83991.1};	45.89	292	151	3	5	293	37	324	7e-74	255
sp:FOLD_BDEBA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.95	287	149	2	5	291	4	281	8e-74	240
gpu:LN847044_8	Bifunctional protein FolD [Chlamydia pneumoniae]	45.04	282	149	3	5	285	2	278	8e-74	240
sp:FOLD_CHLPN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.04	282	149	3	5	285	2	278	8e-74	240
tr:A0A015LXX9_9GLOM	SubName: Full=Trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase ADE3 {ECO:0000313|EMBL:EXX77561.1};	45.89	292	151	3	3	291	2	289	8e-74	254
rs:WP_019269635	methenyltetrahydrofolate cyclohydrolase [Mycoplasma capricolum].	44.29	289	152	3	5	293	3	282	8e-74	240
tr:E6YZ32_BARSR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.80	295	140	7	5	292	4	291	8e-74	240
rs:WP_026168533	methenyltetrahydrofolate cyclohydrolase [Sinorhizobium meliloti].	48.11	291	143	4	5	291	4	290	8e-74	240
rs:WP_034358188	methenyltetrahydrofolate cyclohydrolase [Deinococcus phoenicis].	48.64	257	126	3	34	290	30	280	8e-74	240
rs:WP_015092308	methylenetetrahydrofolate dehydrogenase [Bdellovibrio bacteriovorus].	44.60	287	150	2	5	291	4	281	8e-74	240
rs:WP_038560043	methenyltetrahydrofolate cyclohydrolase [Neorickettsia helminthoeca].	47.06	289	138	5	4	289	3	279	8e-74	240
rs:XP_006356965	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X1 [Solanum tuberosum].	44.22	294	158	2	2	293	75	364	8e-74	243
tr:A0A0C9MDJ2_9FUNG	SubName: Full=DNA, scaffold: scf_mam1_v10004, strain NBRC 6742, whole genome shotgun sequence {ECO:0000313|EMBL:GAN01047.1};	46.26	294	151	3	1	291	1	290	8e-74	254
rs:WP_040929293	methenyltetrahydrofolate cyclohydrolase [Nosocomiicoccus sp. NP2].	43.99	291	150	5	1	291	1	278	8e-74	239
rs:WP_043868897	methenyltetrahydrofolate cyclohydrolase [Celeribacter indicus].	47.44	293	149	2	1	292	1	289	9e-74	240
rs:WP_046105119	methenyltetrahydrofolate cyclohydrolase [Devosia chinhatensis].	45.17	290	154	2	1	289	1	286	9e-74	240
rs:WP_020028333	hypothetical protein [gamma proteobacterium SCGC AAA076-F14].	48.07	285	134	3	4	288	2	272	9e-74	239
sp:FOLD_ANADE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	49.31	288	134	4	5	291	3	279	9e-74	239
rs:WP_024900014	methenyltetrahydrofolate cyclohydrolase, partial [Ochrobactrum rhizosphaerae].	47.24	290	143	5	5	289	3	287	9e-74	240
rs:WP_026172780	methenyltetrahydrofolate cyclohydrolase [Asticcacaulis benevestitus].	46.13	297	148	5	5	296	1	290	9e-74	240
rs:WP_008889793	5,10-methylene-tetrahydrofolate dehydrogenase [Thalassospira profundimaris].	44.83	290	154	2	3	292	4	287	9e-74	240
rs:WP_026622754	methenyltetrahydrofolate cyclohydrolase [Ensifer sp. WSM1721].	47.10	293	147	4	5	293	4	292	9e-74	240
rs:XP_010638911	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Fukomys damarensis].	46.31	298	153	3	3	294	264	560	9e-74	248
rs:WP_023391157	tetrahydrofolate dehydrogenase [Abiotrophia defectiva].	44.37	284	148	2	6	289	4	277	9e-74	240
sp:FOLD_RUEST	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.76	293	151	2	1	292	1	289	9e-74	240
tr:A0A016QPP6_9DEIO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.64	257	126	3	34	290	32	282	1e-73	240
rs:WP_042128823	methenyltetrahydrofolate cyclohydrolase [Pseudomonas japonica].	45.52	290	150	3	3	292	7	288	1e-73	240
rs:WP_047195375	hypothetical protein [[Polyangium] brachysporum].	46.55	290	144	4	1	290	1	279	1e-73	239
rs:WP_020044204	5,10-methylene-tetrahydrofolate dehydrogenase [alpha proteobacterium SCGC AAA298-K06].	46.58	292	150	2	1	292	1	286	1e-73	240
rs:WP_014327368	5,10-methylene-tetrahydrofolate dehydrogenase [Sinorhizobium fredii].	48.29	292	141	5	5	291	4	290	1e-73	240
rs:WP_020290334	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. CFII64].	46.67	285	144	3	2	286	3	279	1e-73	240
tr:A0A098EDT0_ANAPH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.37	289	147	3	5	292	8	289	1e-73	240
rs:WP_043313391	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. PI1].	48.44	289	141	4	2	290	6	286	1e-73	240
tr:A0A074Y4E7_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KEQ92580.1};	46.92	292	148	3	1	289	1	288	1e-73	254
rs:WP_040958888	methenyltetrahydrofolate cyclohydrolase [Sinorhizobium fredii].	47.95	292	142	5	5	291	4	290	1e-73	240
rs:WP_003719634	bifunctional protein FolD [Listeria ivanovii].	49.83	289	134	4	3	291	2	279	1e-73	239
rs:XP_007247241	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like isoform X2 [Astyanax mexicanus].	45.33	289	151	3	2	284	42	329	1e-73	241
rs:WP_021133602	5,10-methylene-tetrahydrofolate dehydrogenase [Phaeospirillum fulvum].	45.52	290	152	2	3	292	4	287	1e-73	240
tr:H1XCH9_9XANT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.00	264	120	3	28	289	6	259	1e-73	239
rs:WP_022176423	bifunctional protein FolD [Firmicutes bacterium CAG:552].	43.25	289	153	2	1	289	1	278	1e-73	239
tr:H2L8I7_ORYLA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSORLP00000002160};	45.30	298	142	4	2	293	50	332	1e-73	241
rs:WP_014674506	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	43.15	292	156	4	1	292	1	282	1e-73	239
rs:WP_023677432	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. LSJC280B00].	48.14	295	137	5	3	289	2	288	1e-73	240
rs:WP_037626775	methenyltetrahydrofolate cyclohydrolase [Streptomyces aureus].	43.69	293	155	4	1	293	1	283	1e-73	239
rs:WP_008362551	bifunctional protein FolD [Mycoplasma sp. G5847].	43.97	282	149	3	5	286	3	275	1e-73	239
rs:WP_013853874	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus kefiranofaciens].	46.59	279	137	3	5	283	4	270	1e-73	239
rs:WP_026853429	methenyltetrahydrofolate cyclohydrolase [Geothrix fermentans].	47.21	305	141	3	3	291	2	302	1e-73	240
rs:WP_014963587	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Nitrosopumilus].	44.90	294	148	4	1	292	1	282	1e-73	239
rs:WP_036912274	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus].	44.37	284	151	2	6	286	5	284	1e-73	240
rs:WP_039614840	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. C5pp].	46.85	286	142	4	4	288	8	284	1e-73	240
rs:WP_006170815	methenyltetrahydrofolate cyclohydrolase [Synechococcus sp. WH 5701].	46.64	283	140	2	6	288	5	276	1e-73	240
rs:XP_006481276	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X1 [Citrus sinensis].	44.59	296	155	3	2	292	73	364	1e-73	242
rs:WP_043338952	methenyltetrahydrofolate cyclohydrolase [Belnapia moabensis].	46.02	289	142	3	1	289	1	275	1e-73	239
rs:XP_002906736	bifunctional folD protein [Phytophthora infestans T30-4].	41.91	303	162	4	1	293	1	299	1e-73	240
rs:WP_028310360	hypothetical protein [Derxia gummosa].	47.77	291	141	4	1	291	1	280	1e-73	239
rs:WP_030779526	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-920].	44.33	291	152	5	1	291	1	281	1e-73	239
rs:WP_047135863	methenyltetrahydrofolate cyclohydrolase [Luteimonas sp. FCS-9].	47.39	287	139	3	1	285	7	283	1e-73	239
rs:WP_043300996	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. M47T1].	48.43	287	140	3	6	292	11	289	1e-73	239
rs:WP_036126934	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Lysinibacillus].	45.73	293	148	3	1	293	1	282	1e-73	239
rs:WP_046615132	methenyltetrahydrofolate cyclohydrolase [Pseudomonas putida].	46.88	288	143	4	2	288	6	284	1e-73	240
sp:FOLD2_PSEPG	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.99	287	147	3	2	288	6	284	1e-73	240
rs:WP_046761837	methenyltetrahydrofolate cyclohydrolase [Sphingobium chungbukense].	48.78	287	142	2	3	289	4	285	1e-73	239
rs:WP_039981344	5,10-methylene-tetrahydrofolate cyclohydrolase [Selenomonas sp. oral taxon 149].	47.93	290	138	4	3	290	2	280	1e-73	239
rs:WP_023452244	hypothetical protein [Asticcacaulis sp. AC460].	45.67	289	148	3	5	288	8	292	1e-73	240
rs:XP_007557969	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Poecilia formosa].	47.65	298	149	3	2	293	20	316	1e-73	240
rs:WP_044132058	5,10-methylene-tetrahydrofolate cyclohydrolase [Thaumarchaeota archaeon SCGC AAA007-O23].	44.22	294	150	4	1	292	1	282	1e-73	239
rs:WP_009874439	bifunctional protein FolD [Buchnera aphidicola].	43.45	290	154	2	1	290	1	280	1e-73	239
tr:A0A075XAJ8_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.24	290	143	5	5	289	3	287	1e-73	239
rs:WP_022928503	methenyltetrahydrofolate cyclohydrolase [Patulibacter americanus].	44.48	290	157	1	1	290	1	286	1e-73	239
rs:WP_035837812	methenyltetrahydrofolate cyclohydrolase [Defluviimonas sp. 20V17].	45.55	292	154	2	1	291	1	288	1e-73	239
rs:WP_027632910	methenyltetrahydrofolate cyclohydrolase [Clostridium hydrogeniformans].	42.81	292	156	2	3	294	2	282	1e-73	239
rs:WP_036906611	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus marinus].	44.95	287	150	2	4	286	3	285	1e-73	239
rs:WP_018897622	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium sp. 2MFCol3.1].	46.94	294	148	4	3	292	2	291	2e-73	239
rs:WP_009503187	5,10-methylene-tetrahydrofolate dehydrogenase [Citreicella sp. 357].	45.89	292	153	2	1	292	1	287	2e-73	239
rs:XP_010324899	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X5 [Solanum lycopersicum].	43.88	294	159	2	2	293	66	355	2e-73	241
rs:WP_027168376	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. WSM3224].	48.30	294	136	5	4	289	3	288	2e-73	239
rs:WP_046820319	methenyltetrahydrofolate cyclohydrolase [Pseudomonas putida].	46.53	288	146	3	2	289	3	282	2e-73	239
rs:WP_014562538	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus fermentum].	46.23	292	143	4	4	292	3	283	2e-73	239
rs:WP_007255048	5,10-methylene-tetrahydrofolate dehydrogenase [Oceanicola granulosus].	46.55	290	149	2	3	292	2	285	2e-73	239
tr:A0A075GIH2_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.32	285	147	2	5	289	4	282	2e-73	239
rs:WP_006699282	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium lupini].	47.95	292	139	6	1	285	1	286	2e-73	239
rs:WP_028041225	methenyltetrahydrofolate cyclohydrolase [Caulobacter sp. URHA0033].	44.64	289	154	2	3	291	4	286	2e-73	239
rs:XP_004244964	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X6 [Solanum lycopersicum].	43.88	294	159	2	2	293	65	354	2e-73	241
sp:FOLD_ANAMM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.48	290	153	4	4	292	3	285	2e-73	239
rs:WP_023839118	5,10-methylene-tetrahydrofolate dehydrogenase [Blastomonas sp. CACIA14H2].	46.39	291	151	2	1	291	1	286	2e-73	239
rs:WP_030165413	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-813].	42.66	293	158	4	1	293	1	283	2e-73	239
rs:WP_016487665	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas putida].	46.53	288	146	3	1	288	5	284	2e-73	239
rs:WP_023381172	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas].	46.83	284	143	3	2	285	6	281	2e-73	239
rs:XP_004363453	mthfd1 protein [Capsaspora owczarzaki ATCC 30864].	46.62	296	151	3	1	293	1	292	2e-73	253
rs:WP_005274476	5,10-methylene-tetrahydrofolate dehydrogenase [Arthrobacter crystallopoietes].	45.61	296	148	6	3	292	10	298	2e-73	239
rs:WP_038046248	methenyltetrahydrofolate cyclohydrolase [Thermus caliditerrae].	45.30	287	141	4	3	289	4	274	2e-73	239
rs:WP_018927682	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas].	47.02	285	143	3	5	289	6	282	2e-73	239
rs:WP_031352955	methenyltetrahydrofolate cyclohydrolase [Ochrobactrum intermedium].	47.64	296	145	5	3	292	2	293	2e-73	239
rs:WP_027999507	methenyltetrahydrofolate cyclohydrolase [Sinorhizobium arboris].	47.08	291	146	4	5	291	4	290	2e-73	239
rs:WP_003992469	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces viridochromogenes].	43.00	293	157	4	1	293	1	283	2e-73	239
tr:U4V714_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.64	296	145	5	3	292	8	299	2e-73	239
sp:FOLD_ANAPZ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.67	289	149	3	5	292	8	289	2e-73	239
rs:WP_026842053	5,10-methylene-tetrahydrofolate cyclohydrolase [Geobacter bremensis].	45.55	292	151	4	4	293	2	287	2e-73	239
rs:WP_046383911	methenyltetrahydrofolate cyclohydrolase [Pseudomonas veronii].	48.07	285	140	3	6	290	12	288	2e-73	239
rs:WP_023783712	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. LNHC220B00].	47.46	295	139	5	3	289	2	288	2e-73	239
rs:WP_015836617	5,10-methylene-tetrahydrofolate dehydrogenase [Geobacter sp. M21].	45.55	292	151	4	4	293	2	287	2e-73	239
rs:WP_027062478	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium loti].	46.10	295	143	5	3	289	2	288	2e-73	239
rs:WP_028124082	methenyltetrahydrofolate cyclohydrolase [Entomoplasma melaleucae].	43.79	290	154	2	4	293	2	282	2e-73	239
rs:WP_003126206	tetrahydrofolate dehydrogenase [Enterococcus gallinarum].	46.37	289	144	4	5	293	4	281	2e-73	239
rs:WP_027302078	methenyltetrahydrofolate cyclohydrolase [Rhodospirillales bacterium URHD0088].	45.52	290	151	3	2	291	7	289	2e-73	239
tr:A0A0D3EZY3_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART02G01580.1};	48.85	260	127	2	34	291	9	264	2e-73	238
rs:WP_014953980	5,10-methylene-tetrahydrofolate dehydrogenase [alpha proteobacterium HIMB5].	44.44	288	149	3	5	292	3	279	2e-73	239
rs:WP_022707728	5,10-methylene-tetrahydrofolate dehydrogenase [Paracoccus zeaxanthinifaciens].	45.89	292	146	3	1	292	1	280	2e-73	239
rs:WP_043746416	methenyltetrahydrofolate cyclohydrolase [Oceanicola sp. 22II-S11g].	46.76	293	151	2	1	292	1	289	2e-73	239
rs:WP_027236198	methenyltetrahydrofolate cyclohydrolase [Leisingera caerulea].	46.42	293	152	2	1	292	1	289	2e-73	239
rs:WP_027134159	methenyltetrahydrofolate cyclohydrolase [Geminicoccus roseus].	44.22	294	153	3	4	292	3	290	2e-73	239
rs:WP_026364875	5,10-methylene-tetrahydrofolate cyclohydrolase [gamma proteobacterium SCGC AAA076-E13].	47.72	285	135	3	4	288	2	272	2e-73	238
rs:XP_011652923	PREDICTED: bifunctional protein FolD 2 isoform X2 [Cucumis sativus].	47.35	264	133	2	32	293	15	274	2e-73	238
tr:A0A059EDQ4_9RHOB	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.63	292	138	5	1	289	1	283	2e-73	242
sp:FOLD_METTP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.64	289	145	3	5	293	2	275	2e-73	238
rs:WP_035080087	methenyltetrahydrofolate cyclohydrolase [Caulobacter henricii].	44.37	293	155	2	3	291	4	292	2e-73	239
tr:A0A087Y1W8_POEFO	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPFOP00000012021}; Flags: Fragment;	47.65	298	149	3	2	293	26	322	2e-73	240
rs:WP_040488853	methenyltetrahydrofolate cyclohydrolase [Fulvimarina pelagi].	46.67	300	141	6	5	292	6	298	2e-73	239
rs:WP_022687127	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas phyllosphaerae].	47.08	291	142	4	1	291	1	279	2e-73	239
rs:WP_008895798	5,10-methylene-tetrahydrofolate dehydrogenase [Haloterrigena salina].	45.36	302	144	4	5	289	4	301	2e-73	239
sp:FOLD_PROMT	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.30	287	149	3	4	286	3	285	2e-73	239
rs:WP_016473735	MULTISPECIES: hypothetical protein [Sutterella].	48.48	297	138	7	1	293	1	286	2e-73	239
rs:WP_008755947	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodobacteraceae bacterium KLH11].	46.23	292	150	2	1	292	1	285	2e-73	239
tr:L5KYJ6_PTEAL	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:ELK16457.1};	41.38	348	147	4	3	294	49	395	2e-73	242
rs:WP_006562671	methenyltetrahydrofolate cyclohydrolase [Oscillochloris trichoides].	44.90	294	151	3	1	294	1	283	2e-73	239
rs:WP_010036388	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces chartreusis].	43.00	293	157	4	1	293	1	283	2e-73	238
rs:WP_035053913	5,10-methylene-tetrahydrofolate cyclohydrolase [Carnobacterium pleistocenium].	44.33	291	151	3	1	291	1	280	2e-73	239
rs:WP_046476781	methenyltetrahydrofolate cyclohydrolase [Filomicrobium sp. W].	46.67	285	146	2	4	288	5	283	2e-73	239
rs:WP_044992842	5,10-methylene-tetrahydrofolate cyclohydrolase [Clostridium sp. ATCC 29733].	49.22	256	120	2	34	289	24	269	2e-73	238
rs:WP_045387184	methenyltetrahydrofolate cyclohydrolase [Falsirhodobacter sp. alg1].	46.92	292	147	3	1	292	1	284	3e-73	239
tr:U5CNW5_THEYO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.00	293	151	5	1	293	1	277	3e-73	238
rs:WP_024746479	methenyltetrahydrofolate cyclohydrolase [Lactobacillus namurensis].	47.18	284	137	4	5	286	4	276	3e-73	239
rs:WP_013653531	5,10-methylene-tetrahydrofolate dehydrogenase [Polymorphum gilvum].	46.08	293	150	4	5	293	6	294	3e-73	239
rs:WP_003868780	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Thermoanaerobacter].	42.21	289	151	4	5	293	2	274	3e-73	238
rs:WP_030013704	methenyltetrahydrofolate cyclohydrolase [Streptomyces lavendulae].	42.81	292	157	4	1	292	1	282	3e-73	238
rs:XP_010036051	PREDICTED: bifunctional protein FolD 1, mitochondrial [Eucalyptus grandis].	44.56	294	155	4	2	292	74	362	3e-73	241
rs:WP_009573133	5,10-methylene-tetrahydrofolate dehydrogenase [Celeribacter baekdonensis].	47.78	293	148	2	1	292	1	289	3e-73	239
rs:WP_022698900	5,10-methylene-tetrahydrofolate dehydrogenase [Maricaulis sp. JL2009].	46.53	288	149	2	1	287	1	284	3e-73	239
rs:WP_028805509	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. 142MFCol3.1].	42.66	293	158	4	1	293	1	283	3e-73	238
tr:U2DNF9_CLOS4	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:ERI98008.1}; Flags: Fragment;	49.22	256	120	2	34	289	26	271	3e-73	238
rs:WP_023681888	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium].	47.80	295	138	5	3	289	2	288	3e-73	239
rs:WP_013823010	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfotomaculum kuznetsovii].	44.48	290	149	4	1	290	1	278	3e-73	238
rs:WP_039843992	methenyltetrahydrofolate cyclohydrolase [Rhizobium gallicum].	45.89	292	150	4	5	292	4	291	3e-73	239
rs:XP_011340812	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Cerapachys biroi].	47.10	293	147	3	3	289	90	380	3e-73	242
rs:WP_005471160	MULTISPECIES: tetrahydrofolate dehydrogenase [Enterococcus].	46.37	289	144	4	5	293	4	281	3e-73	238
gpu:CP009498_1147	Methylenetetrahydrofolate dehydrogenase [Candidatus Endomicrobium sp. Rsa215]	44.37	293	144	3	4	288	2	283	3e-73	238
sp:FOLD_CHESB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.14	297	140	6	4	292	3	290	3e-73	239
tr:A0A075G227_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.02	291	146	5	1	289	1	279	3e-73	238
rs:WP_026389587	methenyltetrahydrofolate cyclohydrolase [Acholeplasma multilocale].	44.14	290	153	3	4	293	2	282	3e-73	238
rs:WP_014158644	5,10-methylene-tetrahydrofolate dehydrogenase [Blattabacterium sp. (Mastotermes darwiniensis)].	40.97	288	166	2	3	289	2	286	3e-73	239
rs:XP_011502981	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Ceratosolen solmsi marchali].	46.60	294	148	4	3	290	28	318	3e-73	239
tr:B3T423_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.67	291	147	5	1	289	1	279	3e-73	238
rs:WP_016440563	FolD protein [Coprococcus sp. HPP0048].	46.53	288	143	3	4	291	3	279	3e-73	238
tr:R9XG12_ASHAC	SubName: Full=AaceriAER178Wp {ECO:0000313|EMBL:AGO12518.1};	45.55	292	152	3	5	293	30	317	3e-73	253
rs:WP_016999658	tetrahydrofolate dehydrogenase [Staphylococcus lentus].	44.14	290	151	3	1	290	1	279	3e-73	238
tr:A0A0C5NNY1_YEASX	SubName: Full=MIS1 protein {ECO:0000313|EMBL:AJQ01243.1};	45.89	292	151	3	5	293	37	324	3e-73	253
rs:WP_023772816	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium].	47.46	295	139	5	3	289	2	288	3e-73	239
rs:WP_003002422	tetrahydrofolate dehydrogenase [Streptococcus parasanguinis].	48.44	289	139	3	5	293	4	282	3e-73	238
tr:A0A087RRN8_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.56	294	149	4	1	292	1	282	3e-73	238
rs:WP_024864651	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. FCS014].	47.04	287	139	4	5	289	3	278	3e-73	238
rs:WP_020699031	hypothetical protein [Reyranella massiliensis].	45.95	296	145	4	3	291	4	291	3e-73	239
rs:WP_024098259	5,10-methylene-tetrahydrofolate dehydrogenase [Phaeobacter gallaeciensis].	46.08	293	153	2	1	292	1	289	3e-73	239
rs:WP_015599558	5,10-methylene-tetrahydrofolate dehydrogenase [Hyphomicrobium denitrificans].	46.45	282	145	2	3	284	4	279	3e-73	239
rs:WP_013570807	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Thermoanaerobacter].	42.21	289	151	4	5	293	2	274	3e-73	238
rs:WP_038022592	methenyltetrahydrofolate cyclohydrolase [Tatumella morbirosei].	45.14	288	151	3	3	290	7	287	3e-73	238
rs:WP_039225934	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Clostridium].	43.73	279	146	2	6	284	5	272	3e-73	238
rs:WP_026446028	methenyltetrahydrofolate cyclohydrolase [Acidobacteriaceae bacterium URHE0068].	43.89	303	148	5	4	290	3	299	3e-73	239
rs:WP_030983251	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL WC-3744].	42.81	292	157	4	1	292	1	282	3e-73	238
tr:A0A075GKG4_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.02	291	146	5	1	289	1	279	3e-73	238
rs:WP_006140785	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces griseoaurantiacus].	43.00	293	157	4	1	293	1	283	3e-73	238
rs:WP_027963403	5,10-methylene-tetrahydrofolate cyclohydrolase [Halalkalibacillus halophilus].	41.24	291	160	3	1	291	1	280	3e-73	238
rs:XP_007557968	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Poecilia formosa].	47.65	298	149	3	2	293	40	336	4e-73	240
rs:WP_029757756	methenyltetrahydrofolate cyclohydrolase [Fusobacterium nucleatum].	45.64	287	144	4	5	290	2	277	4e-73	238
sp:FOLD_PROMM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.37	284	151	2	6	286	5	284	4e-73	239
rs:XP_011173550	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Solenopsis invicta].	45.95	296	152	3	3	292	28	321	4e-73	240
rs:XP_003668162	hypothetical protein NDAI_0A07650 [Naumovozyma dairenensis CBS 421].	45.70	291	151	3	6	293	38	324	4e-73	253
rs:WP_005431730	5,10-methylene-tetrahydrofolate dehydrogenase [Sutterella wadsworthensis].	47.64	296	142	5	1	293	1	286	4e-73	238
rs:WP_015639225	bifunctional protein FolD [Lactobacillus fermentum].	45.89	292	144	4	4	292	3	283	4e-73	238
rs:WP_025259941	methenyltetrahydrofolate cyclohydrolase [Pseudomonas cichorii].	46.32	285	145	3	2	286	3	279	4e-73	239
rs:WP_035249146	methenyltetrahydrofolate cyclohydrolase [Actibacterium atlanticum].	46.08	293	153	2	1	292	1	289	4e-73	239
rs:WP_022717194	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium mongolense].	45.70	291	150	4	5	291	4	290	4e-73	239
rs:WP_046665726	methenyltetrahydrofolate cyclohydrolase [Neorhizobium galegae].	45.27	296	154	4	1	292	2	293	4e-73	238
tr:A0A0B3ACZ7_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.86	285	146	3	1	285	1	271	4e-73	238
rs:WP_038068988	methenyltetrahydrofolate cyclohydrolase [Thioclava dalianensis].	45.73	293	154	2	1	292	1	289	4e-73	239
rs:WP_019584749	5,10-methylene-tetrahydrofolate dehydrogenase [Deinococcus apachensis].	47.47	257	128	3	34	290	30	279	4e-73	238
rs:WP_046025325	methenyltetrahydrofolate cyclohydrolase [Lactobacillus fermentum].	45.89	292	144	4	4	292	3	283	4e-73	238
rs:WP_024896426	methenyltetrahydrofolate cyclohydrolase [Ochrobactrum rhizosphaerae].	47.28	294	147	4	3	292	2	291	4e-73	238
rs:WP_012754783	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella grahamii].	46.10	295	147	5	4	292	3	291	4e-73	238
rs:WP_046791700	methenyltetrahydrofolate cyclohydrolase [Tatumella morbirosei].	45.14	288	151	3	3	290	11	291	4e-73	238
tr:L1L4Y6_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.34	293	156	4	1	293	1	283	4e-73	238
rs:WP_037187366	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. YR519].	45.89	292	150	4	5	292	4	291	4e-73	238
rs:XP_009515839	hypothetical protein PHYSODRAFT_309389 [Phytophthora sojae].	40.92	303	165	4	1	293	1	299	4e-73	239
tr:I4N457_9PSED	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.43	287	140	3	6	292	32	310	4e-73	239
rs:WP_044142433	methenyltetrahydrofolate cyclohydrolase [Anaplasma phagocytophilum].	46.67	285	144	3	5	288	8	285	4e-73	239
rs:WP_023740460	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. LNJC395A00].	47.80	295	138	5	3	289	2	288	4e-73	238
rs:WP_039538862	methenyltetrahydrofolate cyclohydrolase [Ruegeria sp. ANG-R].	46.23	292	150	2	1	292	1	285	4e-73	238
rs:XP_004302490	PREDICTED: bifunctional protein FolD 1, mitochondrial [Fragaria vesca subsp. vesca].	42.32	293	163	2	2	292	109	397	4e-73	242
rs:WP_006626376	5,10-methylene-tetrahydrofolate dehydrogenase [Bulleidia extructa].	43.49	292	151	3	3	294	2	279	4e-73	238
tr:S0DEM4_9ZZZZ	SubName: Full=Putative tetrahydrofolate dehydrogenase/cyclohydrolase family protein {ECO:0000313|EMBL:CCO21364.1};	46.85	286	141	4	1	286	57	331	4e-73	240
rs:WP_030789408	methenyltetrahydrofolate cyclohydrolase [Streptomyces lavenduligriseus].	43.15	292	156	4	1	292	1	282	4e-73	238
rs:WP_015498662	5,10-methylene-tetrahydrofolate dehydrogenase [Octadecabacter antarcticus].	45.89	292	152	2	1	292	1	286	4e-73	238
rs:WP_036720892	methenyltetrahydrofolate cyclohydrolase [Paracoccus sphaerophysae].	45.70	291	147	3	1	291	1	280	4e-73	238
sp:FOLD_NITMS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.88	294	151	4	1	292	1	282	4e-73	238
rs:XP_454511	hypothetical protein [Kluyveromyces lactis NRRL Y-1140].	45.70	291	151	3	5	292	36	322	4e-73	253
rs:WP_043199080	methenyltetrahydrofolate cyclohydrolase [Pseudomonas putida].	46.69	287	145	3	2	288	6	284	4e-73	238
rs:WP_046516193	methenyltetrahydrofolate cyclohydrolase [Salinicoccus sp. SV-16].	43.45	290	151	4	1	290	1	277	4e-73	238
rs:WP_031314155	5,10-methylene-tetrahydrofolate cyclohydrolase [Caldanaerobacter subterraneus].	43.25	289	148	5	5	293	2	274	4e-73	238
sp:FOLD_BUCAI	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.10	290	155	2	1	290	1	280	4e-73	238
rs:XP_002519982	methylenetetrahydrofolate dehydrogenase, putative [Ricinus communis].	44.71	293	154	4	3	292	67	354	4e-73	240
rs:WP_008388933	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodovulum sp. PH10].	47.60	292	149	1	1	292	1	288	4e-73	238
rs:WP_005628026	5,10-methylene-tetrahydrofolate dehydrogenase [Ruegeria mobilis].	46.76	293	151	2	1	292	1	289	4e-73	238
rs:WP_037423972	methenyltetrahydrofolate cyclohydrolase [Sinorhizobium sp. CCBAU 05631].	47.60	292	143	5	5	291	4	290	4e-73	238
sp:FOLD_PROMA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.61	285	148	2	5	286	4	284	5e-73	238
rs:WP_023049264	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas putida].	46.18	288	147	3	1	288	5	284	5e-73	238
rs:WP_019962676	5,10-methylene-tetrahydrofolate dehydrogenase [Pannonibacter phragmitetus].	46.44	295	150	4	3	293	4	294	5e-73	238
rs:WP_046118895	methenyltetrahydrofolate cyclohydrolase [Sinorhizobium sp. PC2].	46.13	297	149	6	1	292	4	294	5e-73	238
rs:WP_041556130	5,10-methylene-tetrahydrofolate cyclohydrolase [Carnobacterium sp. 17-4].	45.02	291	149	3	1	291	1	280	5e-73	238
rs:WP_037378669	methenyltetrahydrofolate cyclohydrolase [Sinorhizobium americanum].	47.08	291	146	4	5	291	4	290	5e-73	238
rs:WP_023758378	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. LNHC252B00].	47.80	295	138	5	3	289	2	288	5e-73	238
rs:WP_031109204	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-146].	42.66	293	158	4	1	293	1	283	5e-73	238
rs:XP_006963396	predicted protein [Trichoderma reesei QM6a].	46.05	291	150	3	1	288	1	287	5e-73	252
tr:C4V4R8_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.60	292	140	4	1	290	1	281	5e-73	238
tr:B0K9E0_THEP3	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.21	289	151	4	5	293	11	283	5e-73	238
tr:B0K0U7_THEPX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.21	289	151	4	5	293	11	283	5e-73	238
rs:XP_007557967	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Poecilia formosa].	47.65	298	149	3	2	293	50	346	5e-73	240
rs:WP_046110160	methenyltetrahydrofolate cyclohydrolase [Devosia geojensis].	46.39	291	149	4	1	289	1	286	5e-73	238
sp:FOLD_PARL1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.73	293	154	2	1	292	1	289	5e-73	238
rs:WP_006215517	methylenetetrahydrofolate dehydrogenase [Kocuria palustris].	42.95	298	155	7	1	291	1	290	5e-73	238
tr:A0A074VWF5_9PEZI	SubName: Full=FTHFS-domain-containing protein {ECO:0000313|EMBL:KEQ62057.1};	46.58	292	149	3	1	289	1	288	5e-73	252
sp:FOLD_CHLT2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.04	282	149	3	5	285	2	278	5e-73	238
tr:A0A0B8TJX0_LACCA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.89	292	144	4	4	292	3	283	5e-73	238
sp:FOLD2_PARDP	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.83	288	149	2	5	292	9	289	5e-73	238
tr:W9V0X1_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.85	286	144	3	6	291	15	292	5e-73	238
rs:WP_030712694	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-237].	42.81	292	157	4	1	292	1	282	5e-73	238
tr:F1QXT9_DANRE	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSDARP00000070824};	44.26	296	144	4	3	292	51	331	5e-73	239
rs:WP_022801627	5,10-methylene-tetrahydrofolate dehydrogenase [Deinococcus sp. 2009].	48.34	271	130	4	25	292	26	289	5e-73	238
rs:WP_028091790	methenyltetrahydrofolate cyclohydrolase [Donghicola xiamenensis].	47.10	293	150	2	1	292	1	289	5e-73	238
tr:F4BN48_CARS1	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.02	291	149	3	1	291	5	284	5e-73	238
rs:WP_027144793	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. WSM3626].	47.46	295	139	5	3	289	2	288	5e-73	238
rs:WP_037330905	bifunctional protein FolD [Anaplasma marginale].	44.14	290	154	4	4	292	3	285	5e-73	238
rs:WP_007711740	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium sp. AP49].	47.20	286	146	2	4	289	5	285	6e-73	238
rs:WP_014120803	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia japonica].	42.37	295	159	3	4	297	3	287	6e-73	238
rs:WP_006584922	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus jensenii].	44.83	290	148	4	3	292	2	279	6e-73	238
tr:K8EIF5_CARML	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.71	293	151	3	1	293	1	282	6e-73	238
rs:WP_020967689	5,10-methylene-tetrahydrofolate dehydrogenase [Chlamydia trachomatis].	45.04	282	149	3	5	285	2	278	6e-73	238
rs:XP_008197423	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Tribolium castaneum].	45.24	294	153	3	2	289	15	306	6e-73	238
rs:WP_009872364	5,10-methylene-tetrahydrofolate dehydrogenase [Chlamydia trachomatis].	45.04	282	149	3	5	285	2	278	6e-73	238
rs:WP_018389637	5,10-methylene-tetrahydrofolate dehydrogenase [Ancylobacter sp. FA202].	44.48	290	155	2	4	293	5	288	6e-73	238
rs:WP_013165299	5,10-methylene-tetrahydrofolate dehydrogenase [Starkeya novella].	45.17	290	153	2	4	293	5	288	6e-73	238
tr:G4NM49_CHLT4	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.04	282	149	3	5	285	4	280	6e-73	238
rs:WP_009451914	5,10-methylene-tetrahydrofolate dehydrogenase [Nitratireductor indicus].	47.32	298	140	6	3	292	2	290	6e-73	238
rs:WP_021999715	bifunctional protein FolD 1 [Acetobacter sp. CAG:977].	45.42	284	145	2	3	286	2	275	6e-73	238
rs:WP_046872141	hypothetical protein [Pediococcus damnosus].	45.21	292	147	4	3	292	2	282	6e-73	238
rs:WP_023669302	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium].	47.46	295	139	5	3	289	2	288	6e-73	238
rs:XP_009035535	hypothetical protein AURANDRAFT_53178 [Aureococcus anophagefferens].	44.37	293	156	2	4	293	30	318	6e-73	239
tr:A0A0D5C2A9_9ARCH	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:AJW70465.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AJW70465.1}; EC=3.5.4.9 {ECO:0000313|EMBL:AJW70465.1};	44.22	294	150	4	1	292	1	282	6e-73	238
tr:A0A074XMN3_AURPU	SubName: Full=FTHFS-domain-containing protein {ECO:0000313|EMBL:KEQ86785.1};	46.23	292	150	3	1	289	1	288	6e-73	252
sp:FOLD_PROM1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.60	287	151	2	4	286	3	285	6e-73	238
sp:FOLD_METB6	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.85	286	135	5	5	289	4	273	6e-73	237
rs:WP_034492313	methenyltetrahydrofolate cyclohydrolase [Afifella pfennigii].	48.81	295	141	5	3	292	7	296	6e-73	238
rs:WP_007119126	5,10-methylene-tetrahydrofolate dehydrogenase [Oceanibulbus indolifex].	45.89	292	151	3	1	292	1	285	6e-73	238
rs:WP_024067113	5,10-methylene-tetrahydrofolate dehydrogenase [Chlamydia trachomatis].	45.04	282	149	3	5	285	2	278	7e-73	238
rs:WP_036797621	methenyltetrahydrofolate cyclohydrolase [Porphyrobacter sp. HL-46].	47.40	289	147	2	2	289	8	292	7e-73	238
rs:WP_040617520	methenyltetrahydrofolate cyclohydrolase [Roseibium sp. TrichSKD4].	44.93	296	155	4	2	293	3	294	7e-73	238
rs:WP_010442825	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Ruegeria conchae].	46.23	292	150	2	1	292	1	285	7e-73	238
rs:WP_036507335	methenyltetrahydrofolate cyclohydrolase [Nitrincola sp. AK23].	46.85	286	144	3	6	291	8	285	7e-73	238
rs:WP_017927225	5,10-methylene-tetrahydrofolate dehydrogenase [Loktanella hongkongensis].	45.55	292	153	2	1	292	1	286	7e-73	238
rs:WP_027243350	methenyltetrahydrofolate cyclohydrolase [Leisingera daeponensis].	46.98	298	148	4	1	292	1	294	7e-73	238
rs:WP_034823577	methenyltetrahydrofolate cyclohydrolase [Hyphomonas sp. T16B2].	48.11	291	141	4	1	289	1	283	7e-73	238
rs:WP_014131453	5,10-methylene-tetrahydrofolate dehydrogenase [Pelagibacterium halotolerans].	45.79	297	153	4	1	293	1	293	7e-73	238
rs:WP_008034872	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodobacterales bacterium HTCC2255].	45.89	292	154	1	1	292	1	288	7e-73	238
rs:WP_018301854	5,10-methylene-tetrahydrofolate dehydrogenase [Wenxinia marina].	46.92	292	148	3	1	292	1	285	7e-73	238
rs:WP_017904641	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas fuscovaginae].	47.70	283	140	3	6	288	11	285	7e-73	238
rs:WP_035030097	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Proteobacteria].	46.78	295	141	5	3	289	2	288	7e-73	238
rs:WP_030600916	methenyltetrahydrofolate cyclohydrolase [Streptomyces achromogenes].	43.15	292	156	4	1	292	1	282	7e-73	237
rs:XP_003876336	C-1-tetrahydrofolate synthase, cytoplasmic,putative [Leishmania mexicana MHOM/GT/2001/U1103].	43.62	298	159	4	1	293	2	295	7e-73	238
rs:WP_046328702	5,10-methylene-tetrahydrofolate cyclohydrolase [Sneathia sp. Sn35].	45.42	284	142	4	5	286	2	274	7e-73	237
rs:WP_035709439	methenyltetrahydrofolate cyclohydrolase [Haematobacter massiliensis].	44.52	292	156	2	1	292	1	286	7e-73	238
rs:WP_020966797	5,10-methylene-tetrahydrofolate dehydrogenase [Chlamydia trachomatis].	44.68	282	150	3	5	285	2	278	7e-73	238
tr:Q0G098_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.49	299	141	6	6	292	1	292	7e-73	238
sp:FOLD_CHLAD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.98	293	160	2	1	293	1	283	7e-73	237
rs:WP_028482208	methenyltetrahydrofolate cyclohydrolase [Nesiotobacter exalbescens].	45.92	294	151	4	3	292	4	293	7e-73	238
rs:NP_956107	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like [Danio rerio].	44.26	296	144	4	3	292	51	331	7e-73	239
rs:WP_023834058	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. L103C105A0].	47.46	295	139	5	3	289	2	288	7e-73	238
rs:WP_025164562	methenyltetrahydrofolate cyclohydrolase [Pseudomonas taeanensis].	47.44	293	145	4	3	295	4	287	7e-73	238
rs:WP_034851861	methenyltetrahydrofolate cyclohydrolase [Ensifer sojae].	46.74	291	147	4	5	291	4	290	7e-73	238
rs:WP_009756979	5,10-methylene-tetrahydrofolate dehydrogenase [Lachnospiraceae bacterium 2_1_46FAA].	44.79	288	148	3	5	292	4	280	7e-73	237
rs:XP_973311	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X3 [Tribolium castaneum].	45.24	294	153	3	2	289	6	297	7e-73	238
rs:WP_041826248	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus parasanguinis].	48.10	289	140	3	5	293	4	282	7e-73	237
rs:WP_040379549	methenyltetrahydrofolate cyclohydrolase [Deinococcus aquatilis].	48.84	258	125	4	33	290	24	274	7e-73	237
rs:WP_036758022	methenyltetrahydrofolate cyclohydrolase [Paracoccus versutus].	44.67	291	154	2	1	291	1	284	7e-73	238
tr:A0A0D6DX89_9LACT	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:CEN28121.1};	47.06	289	142	4	5	293	3	280	7e-73	237
rs:WP_025046456	methenyltetrahydrofolate cyclohydrolase [Sulfitobacter mediterraneus].	46.76	293	151	2	1	292	1	289	7e-73	238
rs:XP_012169506	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Bombus terrestris].	44.93	296	154	3	3	292	46	338	8e-73	239
rs:WP_010494363	tetrahydrofolate dehydrogenase [Lactobacillus acidipiscis].	44.29	289	150	3	5	293	4	281	8e-73	237
rs:WP_033280120	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-525].	42.66	293	158	4	1	293	1	283	8e-73	237
tr:W1VEJ8_STRPA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.44	289	139	3	5	293	26	304	8e-73	238
rs:WP_045806718	methenyltetrahydrofolate cyclohydrolase [Lactobacillus spicheri].	46.13	284	140	5	5	286	4	276	8e-73	237
rs:WP_027509909	methenyltetrahydrofolate cyclohydrolase [Rhizobium sullae].	45.89	292	150	4	5	292	4	291	8e-73	238
rs:WP_027356047	methenyltetrahydrofolate cyclohydrolase [Desulfotomaculum thermocisternum].	43.79	290	151	4	1	290	1	278	8e-73	237
rs:WP_024926053	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Mesorhizobium].	46.78	295	141	5	3	289	2	288	8e-73	238
rs:WP_020285200	5,10-methylene-tetrahydrofolate dehydrogenase [Osedax symbiont Rs2].	46.18	288	145	4	6	291	5	284	8e-73	237
rs:WP_018381279	hypothetical protein [Streptococcus thoraltensis].	44.64	289	150	3	5	293	4	282	8e-73	237
rs:WP_038359740	methenyltetrahydrofolate cyclohydrolase [Bosea sp. UNC402CLCol].	46.69	287	143	2	2	288	4	280	8e-73	237
rs:WP_046417871	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. MUSC136T].	42.47	292	158	4	1	292	1	282	8e-73	237
rs:WP_039245053	methenyltetrahydrofolate cyclohydrolase [Clostridium novyi].	43.37	279	147	2	6	284	5	272	8e-73	237
rs:WP_014500162	methenyltetrahydrofolate cyclohydrolase [Buchnera aphidicola].	43.79	290	153	2	1	290	1	280	8e-73	237
rs:WP_008556767	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodobacterales bacterium Y4I].	46.33	300	147	3	1	292	1	294	8e-73	238
rs:WP_015468068	methylenetetrahydrofolate dehydrogenase [Micavibrio aeruginosavorus].	44.52	292	150	4	2	292	5	285	8e-73	237
rs:XP_008197422	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Tribolium castaneum].	45.24	294	153	3	2	289	32	323	8e-73	239
rs:WP_022675600	5,10-methylene-tetrahydrofolate dehydrogenase [Novosphingobium sp. B-7].	44.33	291	157	2	1	291	1	286	9e-73	238
rs:WP_013961188	5,10-methylene-tetrahydrofolate dehydrogenase [Roseobacter litoralis].	46.76	293	151	2	1	292	1	289	9e-73	238
tr:S9QH39_9RHOB	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.08	293	153	2	1	292	4	292	9e-73	238
rs:WP_039191430	methenyltetrahydrofolate cyclohydrolase [Aureimonas altamirensis].	45.82	299	154	3	1	295	1	295	9e-73	238
rs:WP_038653557	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. MIT 0801].	44.25	287	152	3	4	286	3	285	9e-73	238
rs:WP_046062873	methenyltetrahydrofolate cyclohydrolase [Pseudomonas kilonensis].	47.20	286	143	3	4	289	5	282	9e-73	238
rs:WP_028613224	methenyltetrahydrofolate cyclohydrolase [Pseudomonas putida].	46.69	287	145	3	2	288	6	284	9e-73	238
rs:WP_047148563	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. LC103].	45.24	294	153	4	3	292	2	291	9e-73	238
rs:WP_039250520	methenyltetrahydrofolate cyclohydrolase [Clostridium novyi].	43.73	279	146	2	6	284	5	272	9e-73	237
rs:WP_037168496	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Rhizobium].	46.23	292	150	2	1	292	1	285	9e-73	238
gp:AX710619_1	Sequence 4 from Patent WO03018813. [Eremothecium gossypii]	45.89	292	151	3	5	293	3	290	1e-72	251
rs:WP_040817438	methenyltetrahydrofolate cyclohydrolase [Litoreibacter arenae].	46.08	293	153	2	1	292	1	289	1e-72	238
rs:WP_035358431	methenyltetrahydrofolate cyclohydrolase, partial [Acholeplasma equifetale].	43.43	274	140	3	5	278	3	261	1e-72	236
rs:WP_025734520	methenyltetrahydrofolate cyclohydrolase [Entomoplasma luminosum].	45.04	282	146	2	4	285	2	274	1e-72	237
rs:WP_025082479	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus fuchuensis].	44.14	290	151	3	4	293	2	280	1e-72	237
rs:WP_043847109	methenyltetrahydrofolate cyclohydrolase [Roseivivax atlanticus].	46.58	292	150	2	1	292	1	286	1e-72	237
rs:WP_023547268	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces roseochromogenus].	42.81	292	157	4	1	292	1	282	1e-72	237
rs:WP_035831791	5,10-methylene-tetrahydrofolate cyclohydrolase [Cyanobium sp. CACIAM 14].	45.80	286	144	2	3	288	2	276	1e-72	237
tr:M3B2H4_SPHMS	SubName: Full=FTHFS-domain-containing protein {ECO:0000313|EMBL:EMF13957.1};	45.55	292	152	3	1	289	1	288	1e-72	251
rs:WP_032524608	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus marinus].	43.60	289	156	3	6	293	5	287	1e-72	237
rs:WP_043677068	methenyltetrahydrofolate cyclohydrolase [Streptomyces xylophagus].	42.66	293	158	4	1	293	1	283	1e-72	237
rs:XP_008416300	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Poecilia reticulata].	47.65	298	149	3	2	293	100	396	1e-72	241
tr:A0A075I005_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.56	294	149	5	1	292	1	282	1e-72	237
rs:XP_003485492	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Bombus impatiens].	44.59	296	155	3	3	292	28	320	1e-72	238
sp:FOLD_CALS4	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.32	293	153	5	1	293	1	277	1e-72	237
rs:WP_013903224	tetrahydrofolate dehydrogenase [Streptococcus parasanguinis].	48.44	289	139	3	5	293	4	282	1e-72	237
rs:WP_034220167	methenyltetrahydrofolate cyclohydrolase [Arenimonas donghaensis].	49.48	287	133	3	1	285	1	277	1e-72	237
rs:WP_046828212	methenyltetrahydrofolate cyclohydrolase [Afipia sp. LC387].	47.06	289	147	2	1	289	1	283	1e-72	237
rs:XP_009038776	hypothetical protein AURANDRAFT_29188, partial [Aureococcus anophagefferens].	44.75	295	155	3	3	293	53	343	1e-72	239
rs:WP_034403124	methenyltetrahydrofolate cyclohydrolase [Deinococcus sp. RL].	49.81	267	126	4	31	296	27	286	1e-72	237
rs:WP_003012104	tetrahydrofolate dehydrogenase [Streptococcus parasanguinis].	48.10	289	140	3	5	293	4	282	1e-72	237
rs:WP_014866454	5,10-methylene-tetrahydrofolate dehydrogenase [Methanoculleus bourgensis].	46.02	289	140	6	5	292	2	275	1e-72	237
rs:WP_046706650	methenyltetrahydrofolate cyclohydrolase [Streptomyces europaeiscabiei].	41.89	296	162	4	1	296	1	286	1e-72	237
rs:WP_028287519	methenyltetrahydrofolate cyclohydrolase [Oceanicola nanhaiensis].	45.73	293	153	3	1	292	1	288	1e-72	237
rs:WP_031132966	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	42.32	293	159	4	1	293	1	283	1e-72	237
rs:WP_027247934	methenyltetrahydrofolate cyclohydrolase [Phaeobacter inhibens].	45.73	293	154	2	1	292	1	289	1e-72	237
rs:WP_019554811	hypothetical protein [Propionispira raffinosivorans].	44.90	294	146	5	1	290	1	282	1e-72	237
rs:WP_035501000	hypothetical protein [Fusobacterium gonidiaformans].	42.35	281	152	2	4	284	2	272	1e-72	237
rs:WP_008214531	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus parafarraginis].	44.71	293	150	4	3	293	2	284	1e-72	237
rs:WP_019173018	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudaminobacter salicylatoxidans].	46.80	297	142	5	4	292	3	291	1e-72	237
rs:WP_029635033	methenyltetrahydrofolate cyclohydrolase [actinobacterium SCGC AAA041-L13].	45.07	284	145	5	1	284	1	273	1e-72	236
sp:FOLD_STRCO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.47	292	158	4	1	292	1	282	1e-72	237
rs:WP_005865952	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella alsatica].	46.60	294	145	5	5	292	4	291	1e-72	237
rs:WP_022571619	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodobacteraceae bacterium HIMB11].	46.05	291	151	2	1	291	1	285	1e-72	237
rs:WP_007195885	5,10-methylene-tetrahydrofolate dehydrogenase [Hoeflea phototrophica].	47.46	295	145	5	3	292	2	291	1e-72	237
rs:WP_023823674	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. L103C565B0].	47.12	295	140	5	3	289	2	288	1e-72	237
rs:WP_004420934	methylenetetrahydrofolate dh [Pseudomonas pseudoalcaligenes].	47.74	287	142	4	4	290	8	286	1e-72	238
rs:WP_043380836	bifunctional protein FolD [Streptomyces mutabilis].	42.12	292	159	4	1	292	1	282	1e-72	237
rs:WP_036711465	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Paracoccus].	46.05	291	146	3	1	291	1	280	1e-72	237
rs:XP_007205395	hypothetical protein PRUPE_ppa007447mg [Prunus persica].	42.81	292	161	2	2	291	75	362	1e-72	239
rs:WP_045699604	methenyltetrahydrofolate cyclohydrolase [Hyphomonas sp. BRH_c22].	48.11	291	141	4	1	289	1	283	1e-72	237
rs:WP_015316295	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium australicum].	47.12	295	140	5	3	289	2	288	1e-72	237
tr:M7YEH9_TRIUA	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:EMS45517.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:TRIUR3_05855-P1};	41.54	325	152	4	3	293	2	322	1e-72	238
rs:XP_008370317	PREDICTED: bifunctional protein FolD 1, mitochondrial [Malus domestica].	42.96	291	160	2	3	291	75	361	1e-72	239
rs:WP_007794332	5,10-methylene-tetrahydrofolate dehydrogenase [Pelagibaca bermudensis].	45.73	293	154	2	1	292	1	289	1e-72	237
rs:WP_037170248	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. CF258].	44.18	292	155	3	1	292	2	285	1e-72	237
rs:WP_038538538	methenyltetrahydrofolate cyclohydrolase [endosymbiont of Acanthamoeba sp. UWC8].	46.71	289	142	3	2	289	3	280	1e-72	237
rs:WP_014879245	5,10-methylene-tetrahydrofolate dehydrogenase [Phaeobacter inhibens].	45.73	293	154	2	1	292	1	289	1e-72	237
rs:WP_044429063	methenyltetrahydrofolate cyclohydrolase [Skermanella aerolata].	45.17	290	154	2	3	292	4	288	1e-72	237
rs:WP_016552793	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium grahamii].	46.58	292	148	4	5	292	4	291	1e-72	237
tr:H3GAT2_PHYRM	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:Phyra72295};	41.53	301	162	4	3	293	2	298	1e-72	237
rs:NP_985035	AER178Wp [Ashbya gossypii ATCC 10895].	45.89	292	151	3	5	293	30	317	1e-72	251
rs:XP_002175274	6,7,8-tetrahydrofolate synthase [Schizosaccharomyces japonicus yFS275].	46.21	290	149	3	3	289	2	287	1e-72	251
rs:WP_018347879	5,10-methylene-tetrahydrofolate dehydrogenase [Longispora albida].	42.27	291	162	4	1	291	1	285	1e-72	237
rs:XP_011644682	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Pogonomyrmex barbatus].	45.61	296	153	3	3	292	28	321	1e-72	238
rs:WP_030053122	methenyltetrahydrofolate cyclohydrolase [Streptomyces peruviensis].	42.32	293	159	4	1	293	1	283	1e-72	236
rs:WP_037698132	methenyltetrahydrofolate cyclohydrolase [Streptomyces scabiei].	42.23	296	161	4	1	296	1	286	1e-72	237
rs:WP_031575963	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus parasanguinis].	48.10	289	140	3	5	293	4	282	1e-72	236
rs:XP_008595128	formate-tetrahydrofolate ligase [Beauveria bassiana ARSEF 2860].	46.74	291	148	3	1	288	1	287	1e-72	251
rs:WP_002713977	FolD protein [Afipia clevelandensis].	46.02	289	150	2	1	289	1	283	1e-72	237
rs:WP_036896855	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus marinus].	42.66	286	159	2	6	291	5	285	1e-72	237
rs:WP_014761134	5,10-methylene-tetrahydrofolate dehydrogenase [Sinorhizobium fredii].	47.26	292	144	5	5	291	4	290	1e-72	237
rs:WP_020025838	hypothetical protein [gamma proteobacterium SCGC AAA076-D13].	47.72	285	135	3	4	288	2	272	1e-72	236
rs:WP_020373291	hypothetical protein [Sulfobacillus thermosulfidooxidans].	42.12	292	158	3	2	293	3	283	1e-72	236
rs:WP_010579697	tetrahydrofolate dehydrogenase [Lactobacillus vini].	45.30	287	146	3	6	292	5	280	1e-72	236
sp:FOLD_PROM0	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.71	288	160	2	6	293	5	287	1e-72	237
rs:WP_035801959	methenyltetrahydrofolate cyclohydrolase [Dasania marina].	47.57	288	143	4	6	291	6	287	1e-72	237
rs:WP_029039911	methenyltetrahydrofolate cyclohydrolase [Cucumibacter marinus].	46.21	290	149	4	1	288	1	285	1e-72	237
rs:WP_039991075	hypothetical protein [Fusobacterium gonidiaformans].	42.35	281	152	2	4	284	2	272	1e-72	236
rs:WP_040572412	5,10-methylene-tetrahydrofolate cyclohydrolase [Selenomonas flueggei].	47.59	290	139	4	3	290	2	280	2e-72	236
rs:WP_039284570	methenyltetrahydrofolate cyclohydrolase [Clostridium botulinum].	43.73	279	146	2	6	284	5	272	2e-72	236
rs:WP_042832961	5,10-methylene-tetrahydrofolate cyclohydrolase [Thermoanaerobacter sp. YS13].	41.87	289	152	4	5	293	2	274	2e-72	236
sp:FOLD_CLONN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.73	279	146	2	6	284	5	272	2e-72	236
rs:WP_034557045	5,10-methylene-tetrahydrofolate cyclohydrolase [Helicobacter muridarum].	46.02	289	145	3	5	293	3	280	2e-72	236
rs:WP_024074673	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. TKP].	46.90	290	145	4	1	289	1	282	2e-72	237
rs:WP_037105713	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. OK665].	46.92	292	145	5	5	291	4	290	2e-72	237
sp:FOLD1_RHIME	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.86	292	153	4	5	292	4	291	2e-72	237
rs:WP_009141609	methenyltetrahydrofolate cyclohydrolase [Collinsella tanakaei].	46.53	288	143	4	3	290	2	278	2e-72	236
rs:WP_009812676	5,10-methylene-tetrahydrofolate dehydrogenase [Roseovarius nubinhibens].	47.26	292	147	3	1	292	1	285	2e-72	237
rs:WP_030609681	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	42.12	292	159	5	1	292	1	282	2e-72	236
tr:I2JRD6_DEKBR	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:EIF45538.1};	43.10	297	160	4	1	292	1	293	2e-72	237
gpu:CP009501_1083	Methylenetetrahydrofolate dehydrogenase (NADP+) [Methanosarcina thermophila TM-1]	47.26	292	143	2	2	293	7	287	2e-72	236
rs:WP_046138682	methenyltetrahydrofolate cyclohydrolase [Devosia insulae].	45.17	290	154	2	1	289	1	286	2e-72	237
tr:E5BEG6_9FUSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.01	288	157	2	5	292	1	278	2e-72	236
tr:E2CPW4_9RHOB	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.93	296	155	4	2	293	40	331	2e-72	238
rs:WP_039532230	methenyltetrahydrofolate cyclohydrolase [Ruegeria sp. ANG-S4].	45.89	292	151	2	1	292	1	285	2e-72	237
rs:WP_014873698	5,10-methylene-tetrahydrofolate dehydrogenase [Phaeobacter gallaeciensis].	45.73	293	154	2	1	292	1	289	2e-72	237
rs:WP_018101118	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	43.30	291	155	5	1	291	1	281	2e-72	236
rs:WP_010702073	methylenetetrahydrofolate dehydrogenase [Bartonella bovis].	47.46	295	141	7	5	292	4	291	2e-72	237
rs:WP_028108397	methenyltetrahydrofolate cyclohydrolase [Ferrimonas futtsuensis].	47.18	284	142	3	6	288	7	283	2e-72	236
rs:WP_037473282	methenyltetrahydrofolate cyclohydrolase [Sphingobium sp. ba1].	47.55	286	145	2	4	289	5	285	2e-72	237
rs:WP_003452237	methylenetetrahydrofolate dehydrogenase [Pseudomonas pseudoalcaligenes].	47.06	289	145	4	4	292	8	288	2e-72	237
rs:WP_009734777	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobiaceae bacterium SG-6C].	46.02	289	150	2	1	289	1	283	2e-72	237
rs:XP_009155938	formate-tetrahydrofolate ligase [Exophiala dermatitidis NIH/UT8656].	46.58	292	149	3	1	289	115	402	2e-72	251
rs:WP_007098243	methenyltetrahydrofolate cyclohydrolase [Synechococcus sp. RS9916].	44.41	286	152	2	6	288	5	286	2e-72	237
rs:WP_008556609	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodobacterales bacterium Y4I].	46.00	300	148	3	1	292	1	294	2e-72	237
rs:WP_004208347	FolD 3 [Sphingobium yanoikuyae].	47.04	287	147	2	3	289	4	285	2e-72	237
rs:WP_028987014	5,10-methylene-tetrahydrofolate cyclohydrolase [Thermicanus aegyptius].	46.02	289	145	4	1	289	1	278	2e-72	236
rs:WP_006202749	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium amorphae].	46.44	295	142	5	3	289	2	288	2e-72	237
tr:A0A075GIN8_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.70	291	144	5	1	289	1	279	2e-72	236
tr:A0A087N8G9_9SPHN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.55	286	145	2	4	289	10	290	2e-72	237
rs:WP_027461852	methenyltetrahydrofolate cyclohydrolase [Deinococcus ficus].	47.97	271	131	4	25	292	26	289	2e-72	236
rs:WP_022706126	5,10-methylene-tetrahydrofolate dehydrogenase [Paracoccus zeaxanthinifaciens].	45.83	288	149	2	1	288	1	281	2e-72	237
rs:WP_008492340	5,10-methylene-tetrahydrofolate dehydrogenase [Acidocella sp. MX-AZ02].	46.71	289	145	3	3	291	2	281	2e-72	236
rs:WP_026442872	methenyltetrahydrofolate cyclohydrolase [Acidobacterium sp. PMMR2].	42.62	305	153	5	2	290	3	301	2e-72	237
rs:WP_027991016	bifunctional protein FolD [Sinorhizobium meliloti].	44.86	292	153	4	5	292	4	291	2e-72	237
rs:WP_025052222	methenyltetrahydrofolate cyclohydrolase [Sulfitobacter sp. NB-68].	46.08	293	153	2	1	292	1	289	2e-72	237
rs:WP_003536320	5,10-methylene-tetrahydrofolate dehydrogenase [Sinorhizobium meliloti].	44.86	292	153	4	5	292	4	291	2e-72	237
rs:WP_042766529	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Streptococcus sp. HSISM1].	48.10	289	140	3	5	293	4	282	2e-72	236
rs:WP_003005994	tetrahydrofolate dehydrogenase [Streptococcus parasanguinis].	48.10	289	140	3	5	293	4	282	2e-72	236
rs:WP_041587154	5,10-methylene-tetrahydrofolate cyclohydrolase [Caldanaerobacter subterraneus].	42.56	289	150	5	5	293	2	274	2e-72	236
rs:WP_017009776	hypothetical protein [Enterovibrio calviensis].	47.57	288	144	3	4	291	8	288	2e-72	236
rs:WP_039458382	methenyltetrahydrofolate cyclohydrolase [endosymbiont of Acanthamoeba sp. UWC36].	46.71	289	142	3	2	289	3	280	2e-72	236
rs:WP_038030181	methenyltetrahydrofolate cyclohydrolase [Thermus sp. NMX2.A1].	45.30	287	141	4	3	289	4	274	2e-72	236
gpu:CP011497_2758	methenyltetrahydrofolate cyclohydrolase [Streptomyces incarnatus]	42.47	292	158	4	1	292	1	282	2e-72	236
rs:WP_017498881	5,10-methylene-tetrahydrofolate dehydrogenase [alpha proteobacterium LLX12A].	47.04	287	147	2	3	289	4	285	2e-72	236
rs:WP_037655986	methenyltetrahydrofolate cyclohydrolase [Streptomyces griseofuscus].	42.12	292	159	4	1	292	1	282	2e-72	236
rs:WP_037509062	methenyltetrahydrofolate cyclohydrolase [Sphingobium yanoikuyae].	47.04	287	147	2	3	289	4	285	2e-72	236
rs:WP_013674254	methenyltetrahydrofolate cyclohydrolase [Pseudonocardia dioxanivorans].	46.21	290	141	4	1	290	1	275	2e-72	236
rs:WP_005773991	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella elizabethae].	46.44	295	144	6	4	291	3	290	2e-72	237
tr:A0A081RM91_9ARCH	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:KEQ56314.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KEQ56314.1}; Flags: Fragment;	44.48	290	147	4	1	288	1	278	2e-72	236
rs:WP_028714627	methenyltetrahydrofolate cyclohydrolase [Paracoccus sp. J55].	45.55	292	152	2	1	292	1	285	2e-72	236
rs:WP_005881879	5,10-methylene-tetrahydrofolate dehydrogenase [Oxalobacter formigenes].	45.73	293	148	4	1	293	1	282	2e-72	236
rs:WP_008838586	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium alhagi].	45.64	298	146	5	3	292	2	291	2e-72	236
rs:WP_019330016	MULTISPECIES: bifunctional protein FolD [Streptomyces].	42.12	292	159	4	1	292	1	282	2e-72	236
rs:WP_029490723	methenyltetrahydrofolate cyclohydrolase [Fusobacterium hwasookii].	45.30	287	145	4	5	290	2	277	2e-72	236
rs:WP_003139069	tetrahydrofolate dehydrogenase [Lactococcus raffinolactis].	46.37	289	144	4	5	293	3	280	2e-72	236
rs:WP_009160331	5,10-methylene-tetrahydrofolate dehydrogenase [Thalassobium sp. R2A62].	46.23	292	150	2	1	292	1	285	2e-72	236
rs:WP_019646865	hypothetical protein [Novispirillum itersonii].	46.58	292	150	2	2	293	10	295	2e-72	236
rs:WP_017442978	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Rickettsia gravesii].	41.36	295	162	3	4	297	3	287	2e-72	236
tr:B1C569_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.95	287	148	3	5	291	3	279	2e-72	236
rs:WP_024289063	methenyltetrahydrofolate cyclohydrolase [Microbacterium sp. KROCY2].	42.95	298	155	7	1	291	1	290	2e-72	236
rs:WP_023820834	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. L2C054A000].	47.46	295	139	5	3	289	2	288	2e-72	236
rs:WP_034573423	5,10-methylene-tetrahydrofolate cyclohydrolase [Carnobacterium divergens].	45.80	286	144	4	6	291	1	275	2e-72	236
rs:WP_031147237	methenyltetrahydrofolate cyclohydrolase [Streptomyces xanthophaeus].	43.64	291	154	5	1	291	1	281	2e-72	236
rs:WP_038074903	methenyltetrahydrofolate cyclohydrolase [Thioclava pacifica].	45.89	292	153	2	1	291	1	288	2e-72	236
rs:WP_003200565	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas].	47.20	286	143	3	4	289	5	282	2e-72	236
sp:FOLD1_ROSDO	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.76	293	151	2	1	292	1	289	2e-72	236
rs:WP_009737685	methenyltetrahydrofolate cyclohydrolase [Frankia sp. QA3].	44.25	287	149	3	1	287	1	276	2e-72	236
tr:G9N966_HYPVG	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHK16487.1};	46.05	291	150	3	1	288	1	287	2e-72	250
rs:WP_009178141	5,10-methylene-tetrahydrofolate dehydrogenase [Silicibacter sp. TrichCH4B].	46.42	293	152	2	1	292	1	289	2e-72	236
rs:WP_014784875	5,10-methylene-tetrahydrofolate dehydrogenase [Terriglobus roseus].	42.76	304	147	7	4	290	5	298	2e-72	237
rs:XP_011064582	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Acromyrmex echinatior].	46.76	293	147	4	3	289	28	317	2e-72	238
rs:WP_030043199	methenyltetrahydrofolate cyclohydrolase [Streptomyces resistomycificus].	42.32	293	159	4	1	293	1	283	2e-72	236
rs:WP_008299233	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Nitrosopumilus salaria].	44.56	294	149	4	1	292	1	282	2e-72	236
rs:WP_020089017	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus parabrevis].	46.85	286	139	5	3	286	2	276	2e-72	236
rs:XP_009370849	PREDICTED: bifunctional protein FolD 1, mitochondrial [Pyrus x bretschneideri].	42.96	291	160	2	3	291	75	361	2e-72	239
rs:WP_036261661	methenyltetrahydrofolate cyclohydrolase [Methylocapsa aurea].	45.82	299	147	5	3	291	8	301	2e-72	237
tr:A0A075G419_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.88	294	151	5	1	292	1	282	2e-72	236
rs:WP_015429817	bifunctional methylenetetrahydrofolate [Blattabacterium sp. (Panesthia angustipennis spadica)].	41.03	290	163	3	1	289	1	283	2e-72	236
rs:WP_029168585	methenyltetrahydrofolate cyclohydrolase [actinobacterium SCGC AAA044-N04].	44.95	287	145	6	1	286	1	275	3e-72	236
rs:WP_042553469	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fulva].	46.18	288	147	3	5	292	4	283	3e-72	236
rs:WP_019066819	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. R1-NS-10].	42.32	293	159	4	1	293	1	283	3e-72	236
rs:WP_036738115	methenyltetrahydrofolate cyclohydrolase [Paracoccus halophilus].	46.05	291	148	3	3	292	10	292	3e-72	237
rs:WP_037133746	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. CF097].	48.44	289	136	7	3	288	9	287	3e-72	236
rs:WP_010338455	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium yanoikuyae].	47.04	287	147	2	3	289	4	285	3e-72	236
rs:WP_027901068	methenyltetrahydrofolate cyclohydrolase [Pseudomonas syringae].	47.24	290	145	4	2	291	3	284	3e-72	236
rs:WP_047168536	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. Y57].	48.97	290	141	3	3	292	2	284	3e-72	236
rs:WP_023508157	bifunctional protein FolD [Rickettsia monacensis].	42.76	290	155	3	4	292	3	282	3e-72	236
rs:WP_035313934	5,10-methylene-tetrahydrofolate cyclohydrolase [Brochothrix campestris].	44.60	287	149	3	5	291	4	280	3e-72	236
tr:A0A068U206_COFCA	SubName: Full=Coffea canephora DH200=94 genomic scaffold, scaffold_7 {ECO:0000313|EMBL:CDP01633.1};	44.48	290	155	2	6	293	80	365	3e-72	238
tr:I1ZKN2_STRPA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.10	289	140	3	5	293	26	304	3e-72	236
rs:WP_042687027	5,10-methylene-tetrahydrofolate cyclohydrolase [Thaumarchaeota archaeon MY2].	46.02	289	142	5	6	292	6	282	3e-72	236
rs:WP_039904854	methenyltetrahydrofolate cyclohydrolase [[Clostridium] spiroforme].	44.95	287	148	3	5	291	2	278	3e-72	236
rs:WP_038068967	methenyltetrahydrofolate cyclohydrolase [Thermus scotoductus].	45.30	287	141	4	3	289	4	274	3e-72	236
rs:XP_004147521	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X2 [Cucumis sativus].	41.64	293	165	2	2	292	65	353	3e-72	238
rs:XP_008550807	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Microplitis demolitor].	45.51	301	150	4	3	294	25	320	3e-72	237
rs:WP_038036357	methenyltetrahydrofolate cyclohydrolase [Thermopetrobacter sp. TC1].	47.39	287	145	2	3	289	4	284	3e-72	236
rs:WP_035093776	methenyltetrahydrofolate cyclohydrolase [Devosia sp. 17-2-E-8].	46.39	291	149	4	1	289	1	286	3e-72	236
rs:WP_030423026	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5065].	42.12	292	159	4	1	292	1	282	3e-72	236
rs:WP_009570442	5,10-methylene-tetrahydrofolate dehydrogenase [Celeribacter baekdonensis].	46.23	292	150	2	1	292	1	285	3e-72	236
rs:WP_003610283	5,10-methylene-tetrahydrofolate dehydrogenase [Weissella confusa].	47.26	292	138	7	4	290	3	283	3e-72	236
rs:XP_012557792	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Hydra vulgaris].	42.43	304	152	5	3	294	10	302	3e-72	236
rs:WP_028011626	methenyltetrahydrofolate cyclohydrolase [Sinorhizobium meliloti].	44.86	292	153	4	5	292	4	291	3e-72	236
rs:XP_454695	hypothetical protein [Kluyveromyces lactis NRRL Y-1140].	46.10	295	149	4	5	293	3	293	3e-72	250
rs:WP_030710500	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-2580].	43.15	292	156	4	1	292	1	282	3e-72	236
rs:WP_031034962	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5650].	42.47	292	158	4	1	292	1	282	3e-72	236
rs:WP_030744569	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-31].	42.47	292	158	4	1	292	1	282	3e-72	236
rs:WP_035029288	methenyltetrahydrofolate cyclohydrolase [Devosia sp. DBB001].	46.39	291	149	4	1	289	1	286	3e-72	236
rs:XP_012221939	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Linepithema humile].	45.82	299	148	4	3	292	28	321	3e-72	238
rs:WP_025063023	methenyltetrahydrofolate cyclohydrolase [Sulfitobacter guttiformis].	46.08	293	153	2	1	292	1	289	3e-72	236
rs:XP_005966204	PREDICTED: c-1-tetrahydrofolate synthase, mitochondrial-like [Pantholops hodgsonii].	47.04	287	147	2	3	289	4	285	3e-72	236
rs:WP_033925495	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. 35-24ZXX].	44.75	295	158	2	1	295	5	294	3e-72	236
rs:WP_045491860	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. StFLB209].	45.70	291	150	3	2	292	3	285	3e-72	236
rs:WP_009724185	5,10-methylene-tetrahydrofolate dehydrogenase [Halomonas sp. TD01].	46.39	291	149	3	3	293	2	285	3e-72	236
sp:FOLD_PROM2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.06	288	159	2	6	293	5	287	3e-72	236
rs:WP_033068063	methenyltetrahydrofolate cyclohydrolase [Thalassospira australica].	44.14	290	156	2	3	292	4	287	3e-72	236
rs:WP_045715187	methenyltetrahydrofolate cyclohydrolase, partial [Salmonella enterica].	50.62	241	115	1	1	241	1	237	3e-72	234
rs:WP_030571541	methenyltetrahydrofolate cyclohydrolase [Streptomyces sclerotialus].	42.66	293	158	4	1	293	1	283	3e-72	236
rs:WP_009807349	5,10-methylene-tetrahydrofolate dehydrogenase [Oceanicola batsensis].	45.21	292	155	2	1	291	1	288	4e-72	236
rs:WP_015716884	5,10-methylene-tetrahydrofolate dehydrogenase [Thermus scotoductus].	45.30	287	141	4	3	289	4	274	4e-72	236
rs:WP_030154841	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-244].	43.15	292	156	5	1	292	1	282	4e-72	236
rs:WP_020470652	hypothetical protein [Zavarzinella formosa].	45.92	294	147	2	1	289	1	287	4e-72	236
rs:WP_031041252	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	42.61	291	157	4	1	291	1	281	4e-72	236
rs:XP_002157732	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Hydra vulgaris].	45.05	293	153	3	3	291	2	290	4e-72	237
rs:WP_020057978	5,10-methylene-tetrahydrofolate dehydrogenase [alpha proteobacterium SCGC AAA076-C03].	45.89	292	154	1	1	292	1	288	4e-72	236
rs:WP_039175077	methenyltetrahydrofolate cyclohydrolase, partial [Leisingera sp. ANG-S5].	46.92	292	148	3	1	292	1	285	4e-72	236
rs:WP_031185310	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5635].	42.47	292	158	4	1	292	1	282	4e-72	236
rs:WP_030864213	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-2747].	43.15	292	156	5	1	292	1	282	4e-72	236
rs:WP_014365824	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia massiliae].	41.69	295	161	3	4	297	3	287	4e-72	236
rs:WP_008886533	5,10-methylene-tetrahydrofolate dehydrogenase [Citreicella sp. SE45].	45.39	293	155	2	1	292	1	289	4e-72	236
sp:FOLD_RHISN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.21	292	152	4	1	289	3	289	4e-72	236
rs:WP_036482692	methenyltetrahydrofolate cyclohydrolase [Nitratireductor basaltis].	46.94	294	147	5	3	292	2	290	4e-72	236
rs:WP_003251154	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas putida].	44.37	293	155	3	2	294	3	287	4e-72	236
rs:WP_004577294	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas putida].	44.37	293	155	3	2	294	3	287	4e-72	236
rs:WP_040184236	methenyltetrahydrofolate cyclohydrolase [Halomonas salina].	45.05	293	154	3	1	293	1	286	4e-72	236
rs:WP_008580446	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia].	42.41	290	156	3	4	292	3	282	4e-72	235
rs:WP_039095043	methenyltetrahydrofolate cyclohydrolase [Kirrobacter mercurialis].	47.90	286	142	3	4	289	2	280	4e-72	236
rs:WP_044827219	methenyltetrahydrofolate cyclohydrolase [Thalassospira sp. HJ].	43.79	290	157	2	3	292	4	287	4e-72	236
rs:WP_028493298	methenyltetrahydrofolate cyclohydrolase [Thermus antranikianii].	44.60	287	143	4	3	289	4	274	4e-72	235
tr:E6Q083_9ZZZZ	SubName: Full=Bifunctional protein folD {ECO:0000313|EMBL:CBI00592.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CBI00592.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CBI00592.1};	41.45	304	156	4	3	290	2	299	4e-72	236
rs:WP_016327088	bifunctional protein FolD [Streptomyces lividans].	42.12	292	159	4	1	292	1	282	4e-72	235
rs:XP_002401635	C1-tetrahydrofolate synthase, putative, partial [Ixodes scapularis].	42.41	290	156	3	4	292	3	282	4e-72	235
rs:WP_044630295	methenyltetrahydrofolate cyclohydrolase [Halomonas meridiana].	45.52	290	152	3	2	290	8	292	4e-72	236
rs:WP_005919076	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium hwasookii].	44.95	287	146	4	5	290	2	277	4e-72	235
rs:WP_008909831	tetrahydrofolate dehydrogenase [Caloramator australicus].	42.91	289	154	2	1	289	1	278	4e-72	235
sp:FOLD1_SINMW	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.08	291	146	4	5	291	4	290	4e-72	236
rs:WP_033525331	methenyltetrahydrofolate cyclohydrolase [Streptomyces galbus].	42.66	293	158	4	1	293	1	283	4e-72	235
rs:XP_011653480	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X1 [Cucumis sativus].	41.64	293	165	2	2	292	73	361	4e-72	238
rs:WP_014408614	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia rhipicephali].	41.69	295	161	3	4	297	3	287	4e-72	235
rs:WP_018206939	hypothetical protein [actinobacterium SCGC AAA024-D14].	44.41	286	148	5	1	286	1	275	4e-72	235
rs:WP_022134078	bifunctional protein FolD [Clostridium sp. CAG:594].	46.69	272	134	2	19	290	14	274	4e-72	235
rs:WP_031477583	methenyltetrahydrofolate cyclohydrolase [Streptomyces bicolor].	41.98	293	160	4	1	293	1	283	4e-72	235
rs:WP_037750156	methenyltetrahydrofolate cyclohydrolase [Streptomyces mirabilis].	42.12	292	159	4	1	292	1	282	4e-72	235
rs:WP_016711160	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas monteilii].	46.18	288	145	4	2	288	6	284	4e-72	236
rs:WP_038275312	methenyltetrahydrofolate cyclohydrolase [actinobacterium acAMD-5].	43.60	289	149	5	1	289	1	275	5e-72	235
tr:W6MED9_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.05	291	151	2	2	292	3	287	5e-72	236
rs:WP_021226660	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium lactosutens].	47.90	286	145	1	4	289	5	286	5e-72	236
rs:WP_009560307	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus pasteurii].	44.64	289	148	3	4	292	3	279	5e-72	235
rs:WP_030787992	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5008].	42.32	293	159	4	1	293	1	283	5e-72	235
rs:WP_006957128	methylenetetrahydrofolate dehydrogenase [Sphingobium japonicum].	46.85	286	147	2	4	289	5	285	5e-72	236
rs:WP_028118257	5,10-methylene-tetrahydrofolate cyclohydrolase [Facklamia sourekii].	43.86	285	149	3	5	289	4	277	5e-72	235
tr:A0A0C5BQZ7_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.22	294	150	4	1	292	1	282	5e-72	235
rs:WP_036144956	5,10-methylene-tetrahydrofolate cyclohydrolase [Lysinibacillus sp. BF-4].	44.67	291	150	4	3	293	2	281	5e-72	235
rs:WP_024278806	methenyltetrahydrofolate cyclohydrolase [Xanthobacter sp. 126].	44.95	287	152	2	6	292	7	287	5e-72	235
rs:WP_009605508	5,10-methylene-tetrahydrofolate dehydrogenase [SAR116 cluster alpha proteobacterium HIMB100].	45.89	292	153	2	1	291	1	288	5e-72	236
rs:WP_007597154	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium sp. PDO1-076].	46.58	292	148	4	5	292	4	291	5e-72	236
rs:WP_005719401	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus crispatus].	45.74	282	139	5	3	283	2	270	5e-72	235
rs:WP_022711166	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudochrobactrum sp. AO18b].	46.60	294	149	4	3	292	8	297	5e-72	236
rs:WP_005888383	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium nucleatum].	44.60	287	147	4	5	290	2	277	5e-72	235
rs:WP_005911655	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium].	44.60	287	147	4	5	290	2	277	5e-72	235
rs:WP_030763170	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	42.47	292	158	4	1	292	1	282	5e-72	235
rs:WP_026440302	methenyltetrahydrofolate cyclohydrolase [Acidocella facilis].	47.24	290	142	5	3	291	2	281	5e-72	235
rs:WP_003017570	tetrahydrofolate dehydrogenase [Streptococcus parasanguinis].	47.75	289	141	3	5	293	4	282	5e-72	235
rs:WP_030930189	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-646].	42.12	292	159	4	1	292	1	282	5e-72	235
rs:WP_033219526	methenyltetrahydrofolate cyclohydrolase [Streptomyces virginiae].	42.47	292	158	4	1	292	1	282	5e-72	235
rs:WP_019099480	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas].	46.18	288	145	4	2	288	6	284	5e-72	236
rs:WP_030290639	methenyltetrahydrofolate cyclohydrolase [Streptomyces katrae].	42.81	292	157	5	1	292	1	282	5e-72	235
rs:WP_041558346	methenyltetrahydrofolate cyclohydrolase [Novosphingobium sp. PP1Y].	47.44	293	146	4	1	293	1	285	5e-72	235
rs:WP_013712820	5,10-methylene-tetrahydrofolate dehydrogenase [Chlamydia pecorum].	42.21	289	161	3	5	292	2	285	5e-72	235
rs:WP_025906613	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus].	42.71	288	160	2	6	293	5	287	5e-72	236
rs:WP_026736904	5,10-methylene-tetrahydrofolate cyclohydrolase [Leptotrichia goodfellowii].	42.91	282	149	3	6	286	4	274	5e-72	235
rs:WP_002729436	5,10-methylene-tetrahydrofolate dehydrogenase [Phaeospirillum molischianum].	45.17	290	153	2	3	292	4	287	6e-72	235
sp:FOLD_RICM5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.69	295	161	3	4	297	3	287	6e-72	235
rs:WP_025924600	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB243_495L20].	43.25	289	157	3	6	293	5	287	6e-72	236
rs:WP_015887744	5,10-methylene-tetrahydrofolate dehydrogenase [Sinorhizobium fredii].	45.21	292	152	4	1	289	15	301	6e-72	236
rs:WP_040172009	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Phaeobacter].	45.05	293	156	2	1	292	1	289	6e-72	236
rs:WP_037108984	methenyltetrahydrofolate cyclohydrolase [Rhizobium alamii].	46.58	292	148	4	5	292	4	291	6e-72	235
rs:WP_046408343	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. Ag1].	46.05	291	145	4	1	291	1	279	6e-72	235
rs:WP_030233466	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	42.32	293	159	4	1	293	1	283	6e-72	235
rs:XP_011692181	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Wasmannia auropunctata].	45.61	296	153	3	3	292	28	321	6e-72	237
rs:WP_016916790	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia honei].	42.03	295	160	3	4	297	3	287	6e-72	235
rs:WP_023719416	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. LSHC420B00].	43.54	333	134	6	3	289	2	326	6e-72	237
rs:WP_014238673	5,10-methylene-tetrahydrofolate dehydrogenase [Azospirillum brasilense].	46.69	287	145	4	3	286	4	285	6e-72	236
rs:WP_018580347	methenyltetrahydrofolate cyclohydrolase [Erysipelothrix tonsillarum].	43.01	286	151	3	5	290	4	277	6e-72	235
rs:WP_017183831	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium xenophagum].	46.85	286	147	2	4	289	5	285	6e-72	235
rs:WP_003365066	tetrahydrofolate dehydrogenase [Clostridium botulinum].	43.37	279	147	2	6	284	5	272	6e-72	235
rs:WP_035669716	methenyltetrahydrofolate cyclohydrolase [Azospirillum brasilense].	46.85	286	146	3	3	286	4	285	6e-72	236
rs:WP_020276454	bifunctional protein FolD [Streptomyces afghaniensis].	41.89	296	162	4	1	296	1	286	6e-72	235
rs:WP_041696219	methenyltetrahydrofolate cyclohydrolase [Agrobacterium vitis].	45.58	294	152	4	3	292	2	291	6e-72	235
rs:WP_007597279	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium sp. PDO1-076].	46.39	291	148	4	5	291	4	290	6e-72	235
rs:WP_014362959	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia rickettsii].	42.37	295	159	3	4	297	3	287	7e-72	235
rs:XP_011629238	PREDICTED: LOW QUALITY PROTEIN: bifunctional protein FolD 4, chloroplastic [Amborella trichopoda].	42.96	291	160	2	2	290	21	307	7e-72	236
rs:WP_046143433	methenyltetrahydrofolate cyclohydrolase [Devosia soli].	46.92	292	147	5	1	289	1	287	7e-72	235
rs:WP_041138050	hypothetical protein [Clostridiaceae bacterium GM1].	45.45	286	146	3	5	290	2	277	7e-72	235
rs:WP_036561844	methenyltetrahydrofolate cyclohydrolase [Oceanicola sp. MCTG156(1a)].	45.39	293	155	2	1	292	1	289	7e-72	235
rs:WP_003594867	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium leguminosarum].	46.76	293	148	4	4	292	3	291	7e-72	235
rs:WP_025969269	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB245a_519G16].	43.25	289	157	3	6	293	5	287	7e-72	235
rs:WP_004165709	5,10-methylene-tetrahydrofolate dehydrogenase [Pediococcus acidilactici].	45.55	292	146	5	4	293	3	283	7e-72	235
rs:WP_037682028	methenyltetrahydrofolate cyclohydrolase [Streptomyces griseus].	41.98	293	160	4	1	293	1	283	7e-72	235
rs:WP_033698888	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. WCS358].	46.32	285	145	4	1	285	5	281	7e-72	235
rs:XP_007725206	C-1-tetrahydrofolate synthase, mitochondrial [Capronia coronata CBS 617.96].	46.23	292	150	3	1	289	1	288	7e-72	249
rs:WP_031164186	methenyltetrahydrofolate cyclohydrolase [Streptomyces durhamensis].	41.78	292	160	4	1	292	1	282	7e-72	235
rs:WP_008195602	5,10-methylene-tetrahydrofolate dehydrogenase [Labrenzia alexandrii].	45.42	295	151	5	2	291	3	292	7e-72	235
gp:CP000683_468	Methylenetetrahydrofolate dehydrogenase [Rickettsia massiliae MTU5]	41.69	295	161	3	4	297	5	289	7e-72	235
rs:WP_025971273	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB245a_521N5].	43.06	288	159	2	6	293	5	287	7e-72	235
rs:WP_019053096	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium xenophagum].	46.85	286	147	2	4	289	5	285	7e-72	235
rs:WP_025861437	methenyltetrahydrofolate cyclohydrolase [Acetobacter papayae].	46.08	293	151	3	1	293	1	286	7e-72	235
rs:WP_046727310	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. MUSC119T].	41.64	293	161	4	1	293	1	283	7e-72	235
rs:WP_004900845	FolD 1 [Acinetobacter brisouii].	46.50	286	145	3	5	290	14	291	7e-72	235
rs:WP_039682583	methenyltetrahydrofolate cyclohydrolase [Deinococcus swuensis].	48.84	258	125	4	33	290	29	279	7e-72	235
rs:WP_008887979	5,10-methylene-tetrahydrofolate dehydrogenase [Citreicella sp. SE45].	45.73	293	154	2	1	292	1	289	7e-72	235
rs:WP_016499087	methylenetetrahydrofolate dehydrogenase [Pseudomonas putida].	46.34	287	146	3	2	288	6	284	8e-72	235
rs:XP_010278896	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X1 [Nelumbo nucifera].	42.52	294	163	2	2	293	69	358	8e-72	237
rs:WP_043872107	methenyltetrahydrofolate cyclohydrolase [Celeribacter indicus].	44.78	297	156	3	1	296	1	290	8e-72	235
rs:WP_025894672	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus].	43.25	289	157	3	6	293	5	287	8e-72	235
rs:WP_035096759	methenyltetrahydrofolate cyclohydrolase [Devosia sp. LC5].	45.17	290	154	2	1	289	1	286	8e-72	235
rs:WP_014364725	bifunctional protein FolD [Rickettsia philipii].	42.37	295	159	3	4	297	3	287	8e-72	235
tr:A0A0B1PB16_UNCNE	SubName: Full=Putative c-1-tetrahydrofolate mitochondrial {ECO:0000313|EMBL:KHJ35877.1};	43.69	293	158	3	1	290	1	289	8e-72	249
rs:WP_024806822	methenyltetrahydrofolate cyclohydrolase [Verrucomicrobia bacterium LP2A].	40.89	291	170	2	2	291	3	292	8e-72	235
rs:WP_033257512	5,10-methylene-tetrahydrofolate cyclohydrolase [Carnobacterium maltaromaticum].	44.44	288	149	3	6	293	1	277	8e-72	234
rs:WP_025972225	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB241_527L22].	43.40	288	158	2	6	293	5	287	8e-72	235
rs:WP_036172840	methenyltetrahydrofolate cyclohydrolase [Maribius sp. MOLA 401].	45.21	292	153	2	1	292	1	285	8e-72	235
rs:WP_045793349	methenyltetrahydrofolate cyclohydrolase [Acinetobacter brisouii].	46.50	286	145	3	5	290	14	291	8e-72	235
rs:WP_007550970	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Nitrosoarchaeum koreensis].	44.90	294	148	4	1	292	1	282	8e-72	234
rs:WP_016434727	FolD 2 [Streptomyces sp. HGB0020].	42.81	292	157	4	1	292	1	282	8e-72	234
rs:WP_014103355	5,10-methylene-tetrahydrofolate dehydrogenase [Micavibrio aeruginosavorus].	43.64	291	152	4	2	291	5	284	8e-72	234
tr:A0A087PPU7_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.33	289	152	2	2	290	12	294	8e-72	235
rs:WP_036740908	methenyltetrahydrofolate cyclohydrolase [Paracoccus halophilus].	45.55	292	152	2	1	292	1	285	8e-72	235
rs:WP_014014326	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia heilongjiangensis].	41.69	295	161	3	4	297	3	287	8e-72	234
rs:WP_029494144	methenyltetrahydrofolate cyclohydrolase [Fusobacterium hwasookii].	44.95	287	146	4	5	290	2	277	8e-72	234
rs:WP_043551419	methenyltetrahydrofolate cyclohydrolase [Acetobacter malorum].	45.33	289	152	2	2	290	14	296	8e-72	235
rs:WP_006935132	5,10-methylene-tetrahydrofolate dehydrogenase [Labrenzia aggregata].	46.26	294	148	5	3	291	4	292	8e-72	235
tr:S6EWI7_ZYGB2	SubName: Full=ZYBA0S12-01904g1_1 {ECO:0000313|EMBL:CDF91567.1};	45.79	297	154	3	4	297	18	310	8e-72	249
rs:WP_026472719	hypothetical protein [Allobaculum stercoricanis].	45.83	288	144	3	5	291	4	280	8e-72	234
tr:B8LP24_PICSI	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:ABR17404.1};	42.66	293	160	4	3	292	2	289	8e-72	235
tr:E6YPJ8_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.86	292	153	4	5	292	4	291	9e-72	235
rs:WP_037115309	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. OV201].	46.23	292	149	4	5	292	4	291	9e-72	235
rs:WP_028717556	methenyltetrahydrofolate cyclohydrolase [Paracoccus sp. J39].	45.21	292	153	2	1	292	1	285	9e-72	235
rs:WP_024090985	5,10-methylene-tetrahydrofolate dehydrogenase [Leisingera methylohalidivorans].	45.89	292	151	2	1	292	1	285	9e-72	235
tr:A0A077X4J8_9FUNG	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CDS14530.1};	45.61	296	154	3	1	293	1	292	9e-72	249
rs:WP_014740872	methenyltetrahydrofolate cyclohydrolase [Modestobacter marinus].	46.02	289	145	2	1	289	1	278	9e-72	234
rs:WP_013479018	5,10-methylene-tetrahydrofolate dehydrogenase [Asticcacaulis excentricus].	45.95	296	146	5	1	289	1	289	9e-72	235
rs:WP_047032686	methenyltetrahydrofolate cyclohydrolase [Hoeflea sp. IMCC20628].	46.60	294	149	4	3	292	2	291	9e-72	235
rs:XP_010278897	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X2 [Nelumbo nucifera].	42.52	294	163	2	2	293	68	357	9e-72	237
rs:WP_005916602	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pediococcus].	45.21	292	147	4	4	293	3	283	9e-72	234
rs:WP_024125520	5,10-methylene-tetrahydrofolate dehydrogenase [Thermosynechococcus sp. NK55a].	48.08	287	143	2	2	288	5	285	9e-72	235
rs:XP_011264309	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Camponotus floridanus].	46.28	296	151	3	3	292	28	321	9e-72	236
rs:WP_037599252	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptococcus parasanguinis].	47.40	289	142	3	5	293	4	282	9e-72	234
rs:XP_007134601	hypothetical protein PHAVU_010G060500g [Phaseolus vulgaris].	44.33	291	156	2	5	293	66	352	9e-72	237
rs:WP_025923340	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB243_495D8].	42.91	289	158	3	6	293	5	287	9e-72	235
rs:WP_032515051	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus marinus].	43.40	288	158	2	6	293	5	287	9e-72	235
tr:A0A068UML2_COFCA	SubName: Full=Coffea canephora DH200=94 genomic scaffold, scaffold_35 {ECO:0000313|EMBL:CDP08853.1};	50.42	238	112	2	56	291	111	344	1e-71	236
rs:WP_027918505	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. URMO17WK12:I8].	45.83	288	146	4	2	288	6	284	1e-71	235
rs:XP_002981055	hypothetical protein SELMODRAFT_114081 [Selaginella moellendorffii].	41.87	289	161	3	6	291	1	285	1e-71	235
rs:WP_043151988	methenyltetrahydrofolate cyclohydrolase [Sphingobium sp. Ant17].	47.55	286	145	2	4	289	5	285	1e-71	235
rs:XP_010324897	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X3 [Solanum lycopersicum].	43.24	296	164	2	2	293	66	361	1e-71	237
rs:WP_041178700	5,10-methylene-tetrahydrofolate cyclohydrolase [Blattabacterium sp. (Panesthia angustipennis spadica)].	40.97	288	162	3	3	289	2	282	1e-71	234
rs:WP_015658352	bifunctional protein FolD [Streptomyces davawensis].	42.32	293	159	4	1	293	1	283	1e-71	234
rs:XP_008907492	hypothetical protein PPTG_13517 [Phytophthora parasitica INRA-310].	40.92	303	165	4	1	293	1	299	1e-71	235
rs:XP_011312193	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Fopius arisanus].	45.67	300	149	4	3	293	27	321	1e-71	236
rs:WP_024312991	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Rhizobium].	45.89	292	150	4	5	292	4	291	1e-71	235
rs:WP_025954705	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB243_498C16].	43.60	289	156	3	6	293	5	287	1e-71	235
rs:WP_008122777	5,10-methylene-tetrahydrofolate dehydrogenase [Phyllobacterium sp. YR531].	46.26	294	150	4	3	292	2	291	1e-71	235
rs:WP_038465568	5,10-methylene-tetrahydrofolate cyclohydrolase [Candidatus Paracaedibacter acanthamoebae].	41.78	292	159	2	3	294	2	282	1e-71	234
rs:WP_033084140	methenyltetrahydrofolate cyclohydrolase [Colwellia psychrerythraea].	48.44	289	139	7	5	290	2	283	1e-71	234
rs:WP_022186267	bifunctional protein FolD [Azospirillum sp. CAG:260].	44.71	293	146	4	1	292	1	278	1e-71	234
rs:WP_018325648	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium giardinii].	46.28	296	151	4	1	292	1	292	1e-71	235
rs:WP_022999442	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Labrenzia].	45.58	294	150	5	3	291	4	292	1e-71	235
rs:WP_023809192	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. L2C084A000].	46.78	295	141	5	3	289	2	288	1e-71	235
rs:WP_013692958	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas].	46.85	286	144	3	4	289	5	282	1e-71	235
rs:WP_006807720	5,10-methylene-tetrahydrofolate dehydrogenase [Leptotrichia goodfellowii].	42.91	282	149	3	6	286	4	274	1e-71	234
tr:U2TJL7_STRPY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.97	246	118	2	49	294	1	236	1e-71	233
rs:WP_045491284	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. StFLB209].	44.52	292	154	3	1	292	5	288	1e-71	235
rs:WP_025044001	methenyltetrahydrofolate cyclohydrolase [Sulfitobacter sp. MM-124].	45.33	300	150	3	1	292	1	294	1e-71	235
rs:WP_025031780	methenyltetrahydrofolate cyclohydrolase [Nitratireductor aquibiodomus].	47.62	294	145	5	3	292	2	290	1e-71	235
rs:WP_028954669	methenyltetrahydrofolate cyclohydrolase [Sulfitobacter sp. 20_GPM-1509m].	46.23	292	151	2	1	292	1	286	1e-71	235
rs:WP_030967253	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5140].	41.78	292	160	4	1	292	1	282	1e-71	234
rs:WP_039152111	methenyltetrahydrofolate cyclohydrolase [Leisingera sp. ANG-DT].	46.58	292	149	3	1	292	1	285	1e-71	234
rs:WP_025935952	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB243_498N4].	42.91	289	158	3	6	293	5	287	1e-71	234
rs:WP_027719267	methenyltetrahydrofolate cyclohydrolase [Desulfovirgula thermocuniculi].	44.48	290	149	3	1	290	1	278	1e-71	234
rs:WP_047093205	methenyltetrahydrofolate cyclohydrolase, partial [Erythrobacter marinus].	45.49	288	150	3	3	290	2	282	1e-71	234
rs:WP_046023058	methenyltetrahydrofolate cyclohydrolase [Magnetospira sp. QH-2].	45.21	292	154	3	3	292	4	291	1e-71	235
rs:WP_023666073	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodobacter sp. CACIA14H1].	46.58	292	149	2	1	292	1	285	1e-71	234
rs:WP_022435682	bifunctional protein FolD [Firmicutes bacterium CAG:321].	44.72	284	143	3	5	288	3	272	1e-71	234
rs:WP_025861082	methenyltetrahydrofolate cyclohydrolase [Acetobacter papayae].	44.98	289	151	4	3	290	5	286	1e-71	234
rs:WP_037098387	methenyltetrahydrofolate cyclohydrolase [Rhizobium alamii].	46.08	293	150	4	4	292	3	291	1e-71	234
tr:F6W7X0_MACMU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000014938}; Flags: Fragment;	45.42	295	147	7	5	293	39	325	1e-71	236
tr:A0A078MFC3_9BACI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.67	291	150	4	3	293	2	281	1e-71	234
rs:WP_026816060	methenyltetrahydrofolate cyclohydrolase [Arenimonas composti].	48.29	292	139	4	1	290	1	282	1e-71	234
rs:WP_038056573	methenyltetrahydrofolate cyclohydrolase [Thermus sp. YIM 77409].	45.30	287	141	4	3	289	4	274	1e-71	234
rs:XP_004498330	PREDICTED: bifunctional protein FolD 1, mitochondrial-like [Cicer arietinum].	44.41	295	156	4	2	293	69	358	1e-71	237
rs:WP_037925464	methenyltetrahydrofolate cyclohydrolase [Sulfitobacter pseudonitzschiae].	46.23	292	151	2	1	292	1	286	1e-71	234
tr:F3EXH8_PSEA0	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.62	253	120	2	38	290	1	243	1e-71	233
tr:H5SAA3_9DEIN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.05	256	121	3	34	289	31	274	1e-71	234
rs:WP_006499579	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus mucosae].	44.52	292	149	5	3	292	2	282	1e-71	234
rs:WP_007006943	5,10-methylene-tetrahydrofolate dehydrogenase [Nitratireductor aquibiodomus].	47.96	294	144	5	3	292	2	290	1e-71	234
rs:WP_034384441	methenyltetrahydrofolate cyclohydrolase [Deinococcus sp. YIM 77859].	49.80	255	121	4	36	290	32	279	1e-71	234
rs:WP_024576866	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Afipia].	47.06	289	147	2	1	289	1	283	1e-71	234
rs:WP_019294977	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Leisingera].	46.58	292	149	3	1	292	1	285	1e-71	234
rs:WP_023488791	bifunctional protein [Lactobacillus crispatus].	45.39	282	140	5	3	283	2	270	1e-71	234
rs:WP_029558718	methenyltetrahydrofolate cyclohydrolase [Xanthobacter sp. 91].	45.14	288	150	4	6	292	7	287	1e-71	234
rs:WP_039255941	methenyltetrahydrofolate cyclohydrolase [Clostridium novyi].	43.01	279	148	2	6	284	5	272	1e-71	234
rs:WP_037139636	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. CF394].	46.58	292	148	4	5	292	4	291	1e-71	234
rs:XP_003747281	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Metaseiulus occidentalis].	43.62	298	159	4	1	293	1	294	1e-71	234
rs:XP_007890161	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Callorhinchus milii].	52.94	238	105	3	62	293	40	276	1e-71	234
rs:WP_044836711	methenyltetrahydrofolate cyclohydrolase [Thalassomonas viridans].	44.64	289	152	4	5	291	2	284	1e-71	234
rs:WP_012840964	5,10-methylene-tetrahydrofolate dehydrogenase [Blattabacterium sp. (Blattella germanica)].	40.34	290	163	4	3	289	2	284	1e-71	234
sp:FOLD_RICRO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.37	295	159	3	4	297	3	287	1e-71	234
rs:WP_014215528	5,10-methylene-tetrahydrofolate dehydrogenase [Pediococcus claussenii].	46.10	295	142	7	3	293	2	283	1e-71	234
rs:WP_029964978	methenyltetrahydrofolate cyclohydrolase [Ensifer sp. USDA 6670].	44.86	292	153	4	5	292	4	291	1e-71	235
rs:WP_027460873	methenyltetrahydrofolate cyclohydrolase [Deinococcus murrayi].	49.06	267	128	4	31	296	27	286	1e-71	234
rs:WP_030382877	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	42.66	293	158	4	1	293	1	283	1e-71	234
rs:WP_014362602	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia rickettsii].	42.37	295	159	3	4	297	3	287	1e-71	234
rs:WP_029058663	methenyltetrahydrofolate cyclohydrolase [Stappia stellulata].	44.71	293	156	3	1	291	1	289	1e-71	234
rs:WP_027256633	methenyltetrahydrofolate cyclohydrolase [Leisingera aquimarina].	45.55	292	152	2	1	292	1	285	1e-71	234
rs:WP_027596183	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. LAIL14HWK12:I7].	46.48	284	144	4	2	285	6	281	1e-71	234
tr:W6KIF1_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.21	292	154	3	3	292	5	292	1e-71	234
rs:WP_042165309	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NBRC 110035].	41.78	292	160	4	1	292	1	282	1e-71	234
rs:WP_025556579	methenyltetrahydrofolate cyclohydrolase [Rhizobiales bacterium JGI 0001002-O7].	46.08	293	150	4	3	291	2	290	1e-71	234
rs:WP_004762801	FolD 1 [Acinetobacter sp. CIP 102529].	47.22	288	141	5	5	290	13	291	1e-71	234
rs:WP_025947382	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus].	43.25	289	157	3	6	293	5	287	2e-71	234
rs:WP_002831456	5,10-methylene-tetrahydrofolate dehydrogenase [Pediococcus acidilactici].	45.24	294	144	5	4	293	3	283	2e-71	234
rs:WP_043919709	methenyltetrahydrofolate cyclohydrolase [Jannaschia aquimarina].	46.39	291	151	2	1	291	1	286	2e-71	234
rs:WP_025975864	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Prochlorococcus sp. scB243_495N3].	43.11	283	156	2	6	288	5	282	2e-71	234
rs:WP_005901138	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium sp. OBRC1].	45.30	287	145	4	5	290	2	277	2e-71	234
tr:W6RQ81_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.89	292	150	4	5	292	26	313	2e-71	235
rs:WP_025056200	methenyltetrahydrofolate cyclohydrolase [Sulfitobacter sp. NB-77].	45.00	300	151	3	1	292	1	294	2e-71	234
rs:WP_025283699	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus helveticus].	45.55	281	141	3	3	283	2	270	2e-71	234
rs:WP_037311967	methenyltetrahydrofolate cyclohydrolase [Ruegeria halocynthiae].	45.21	292	153	2	1	292	1	285	2e-71	234
rs:WP_024010434	5,10-methylene-tetrahydrofolate dehydrogenase [Chlamydia pecorum].	42.21	289	161	3	5	292	2	285	2e-71	234
rs:XP_001470379	putative C-1-tetrahydrofolate synthase, cytoplasmic [Leishmania infantum JPCM5].	44.44	297	156	4	2	293	3	295	2e-71	234
tr:K7UXQ3_MAIZE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AFW82634.1, ECO:0000313|EnsemblPlants:GRMZM2G150485_P06};	41.64	329	150	3	3	293	2	326	2e-71	235
rs:WP_020953178	5,10-methylene-tetrahydrofolate dehydrogenase [Paracoccus aminophilus].	47.08	291	147	2	2	292	8	291	2e-71	234
rs:XP_012660827	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Otolemur garnettii].	45.10	286	122	3	11	294	1	253	2e-71	233
rs:WP_034791899	methenyltetrahydrofolate cyclohydrolase [Hyphomonas beringensis].	47.26	292	142	5	1	289	1	283	2e-71	234
rs:WP_024504809	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium ciceri].	46.78	295	141	5	3	289	2	288	2e-71	234
rs:WP_013530231	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium].	46.44	295	142	5	3	289	2	288	2e-71	234
tr:W0W6J0_ZYGBA	SubName: Full=Probable C-1-tetrahydrofolate synthase,mitochondrial {ECO:0000313|EMBL:CDH17327.1};	45.45	297	155	3	4	297	18	310	2e-71	248
rs:WP_030597569	methenyltetrahydrofolate cyclohydrolase [Streptomyces fulvoviolaceus].	41.98	293	160	4	1	293	1	283	2e-71	234
rs:WP_025387123	methenyltetrahydrofolate cyclohydrolase [Corynebacterium casei].	43.99	291	149	4	1	291	1	277	2e-71	234
rs:WP_019199176	5,10-methylene-tetrahydrofolate dehydrogenase [Afipia birgiae].	47.06	289	147	2	1	289	1	283	2e-71	234
rs:WP_030842053	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-475].	41.98	293	160	4	1	293	1	283	2e-71	234
rs:WP_023448366	hypothetical protein [Asticcacaulis sp. AC402].	45.33	289	149	3	5	288	8	292	2e-71	234
rs:WP_015496202	5,10-methylene-tetrahydrofolate dehydrogenase [Octadecabacter arcticus].	45.89	292	152	2	1	292	1	286	2e-71	234
rs:WP_032087018	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus aquimaris].	44.52	292	147	4	1	292	1	277	2e-71	234
rs:XP_003861620	C-1-tetrahydrofolate synthase, cytoplasmic, putative [Leishmania donovani].	44.44	297	156	4	2	293	3	295	2e-71	234
rs:WP_035538289	methenyltetrahydrofolate cyclohydrolase [Hyphomonas oceanitis].	46.74	291	145	4	1	289	1	283	2e-71	234
rs:WP_028963084	methenyltetrahydrofolate cyclohydrolase [Sulfobacillus thermosulfidooxidans].	41.78	292	159	3	2	293	3	283	2e-71	234
rs:WP_008204075	5,10-methylene-tetrahydrofolate dehydrogenase [Roseobacter sp. SK209-2-6].	45.21	292	153	2	1	292	1	285	2e-71	234
rs:WP_034740577	methenyltetrahydrofolate cyclohydrolase [Hyphomonas chukchiensis].	47.26	292	142	5	1	289	1	283	2e-71	234
tr:A0A075GZ15_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.58	294	153	6	1	292	1	289	2e-71	234
rs:WP_002805447	methenyltetrahydrofolate cyclohydrolase [Prochlorococcus marinus].	42.71	288	160	2	6	293	5	287	2e-71	234
rs:WP_025955865	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus].	42.91	289	158	3	6	293	5	287	2e-71	234
rs:WP_007347959	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella rattimassiliensis].	46.10	295	147	5	4	292	3	291	2e-71	234
rs:WP_022681942	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium sp. YL23].	47.39	287	146	2	3	289	4	285	2e-71	234
sp:FOLD_SYNR3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.79	288	149	3	1	288	1	278	2e-71	234
rs:WP_013068885	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodobacter capsulatus].	47.26	292	147	3	1	292	1	285	2e-71	234
rs:WP_024625580	methenyltetrahydrofolate cyclohydrolase [Lactobacillus fabifermentans].	46.55	290	142	5	5	292	4	282	2e-71	234
rs:WP_005006294	MULTISPECIES: FolD 1 [Acinetobacter].	45.92	294	148	5	2	293	10	294	2e-71	234
rs:WP_025890938	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus].	43.25	289	157	3	6	293	5	287	2e-71	234
sp:FOLD2_STRAW	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.98	293	160	4	1	293	1	283	2e-71	234
rs:XP_011865270	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Vollenhovia emeryi].	45.95	296	152	3	3	292	28	321	2e-71	235
rs:WP_004165209	5,10-methylene-tetrahydrofolate dehydrogenase [Pediococcus acidilactici].	45.24	294	144	5	4	293	3	283	2e-71	234
rs:WP_020248563	hypothetical protein [Marine Group I thaumarchaeote SCGC AB-629-I23].	43.54	294	152	5	1	292	1	282	2e-71	234
rs:WP_019013352	hypothetical protein [Elioraea tepidiphila].	48.25	257	123	2	34	290	30	276	2e-71	233
rs:WP_037241098	methenyltetrahydrofolate cyclohydrolase [Rhodomicrobium udaipurense].	46.50	286	147	2	4	289	12	291	2e-71	234
rs:WP_027881399	methenyltetrahydrofolate cyclohydrolase [Meiothermus rufus].	44.95	287	146	5	6	291	4	279	2e-71	234
rs:XP_012062604	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Atta cephalotes].	45.73	293	151	3	3	289	28	318	2e-71	235
tr:A0A0D6NZF7_9PROT	SubName: Full=Bifunctional [5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase] {ECO:0000313|EMBL:GAN71527.1};	45.89	292	152	2	2	293	12	297	2e-71	234
rs:WP_013001312	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces scabiei].	41.98	293	160	4	1	293	1	283	2e-71	233
rs:XP_004354499	methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase [Dictyostelium fasciculatum].	45.52	290	145	3	4	291	13	291	2e-71	246
rs:WP_042850545	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. MIT 0604].	43.60	289	156	3	6	293	5	287	2e-71	234
rs:WP_009019075	5,10-methylene-tetrahydrofolate dehydrogenase [Luminiphilus syltensis].	48.44	289	139	5	4	290	2	282	2e-71	233
rs:WP_046794257	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. LC145].	46.60	294	149	4	3	292	2	291	2e-71	234
rs:WP_007674754	5,10-methylene-tetrahydrofolate dehydrogenase [alpha proteobacterium BAL199].	46.05	291	152	2	2	291	3	289	2e-71	234
rs:WP_003588504	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium leguminosarum].	46.92	292	147	4	5	292	4	291	2e-71	234
rs:WP_008230979	5,10-methylene-tetrahydrofolate dehydrogenase [Roseobacter sp. CCS2].	44.86	292	155	2	1	292	1	286	2e-71	234
rs:WP_007722252	MULTISPECIES: tetrahydrofolate dehydrogenase [Carnobacterium].	43.99	291	152	4	1	291	1	280	2e-71	233
rs:WP_047004600	methenyltetrahydrofolate cyclohydrolase, partial [Erythrobacter sp. KA37].	47.06	289	144	4	3	290	2	282	3e-71	233
rs:WP_006023415	FolD protein [Afipia broomeae].	46.71	289	148	2	1	289	1	283	3e-71	234
rs:WP_023037495	MULTISPECIES: FolD protein [Fusobacterium].	45.30	287	145	4	5	290	2	277	3e-71	233
rs:WP_005898132	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium nucleatum].	45.30	287	145	4	5	290	2	277	3e-71	233
rs:WP_025094945	methenyltetrahydrofolate cyclohydrolase [Acinetobacter soli].	48.11	291	140	6	2	290	10	291	3e-71	234
sp:FOLD_THEEB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.69	287	147	2	2	288	5	285	3e-71	234
rs:WP_024862413	5,10-methylene-tetrahydrofolate cyclohydrolase [Pediococcus acidilactici].	45.24	294	144	5	4	293	3	283	3e-71	233
tr:G9P543_HYPAI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHK41283.1};	45.36	291	152	3	1	288	1	287	3e-71	248
rs:WP_025905208	methenyltetrahydrofolate cyclohydrolase [Staphylococcus sciuri].	43.10	290	154	3	1	290	1	279	3e-71	233
tr:A0A075GCX9_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.58	294	153	6	1	292	1	289	3e-71	233
sp:FOLD_AZOC5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.60	287	153	2	6	292	7	287	3e-71	233
tr:A0A063ZCI7_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.74	287	134	7	5	290	2	273	3e-71	233
rs:WP_012555033	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium leguminosarum].	46.08	293	150	4	4	292	3	291	3e-71	234
tr:A0A0D6N8D0_9PROT	SubName: Full=Bifunctional [5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase] {ECO:0000313|EMBL:GAN61823.1};	46.53	288	148	2	3	290	13	294	3e-71	234
rs:WP_025959796	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus].	42.71	288	160	2	6	293	5	287	3e-71	234
tr:I7J182_9LACO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.96	291	154	3	1	291	1	279	3e-71	233
rs:WP_012723546	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas fluorescens].	46.29	283	144	3	4	286	5	279	3e-71	234
tr:A0A0D6B567_RHOSU	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolatedehydrogenase/5, 10-methylene-tetrahydrofolatecyclohydrolase {ECO:0000313|EMBL:BAQ70247.1}; EC=1.5.1.5 {ECO:0000313|EMBL:BAQ70247.1};	44.37	293	158	2	1	292	1	289	3e-71	234
rs:WP_029380372	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	44.83	290	152	3	3	292	7	288	3e-71	234
rs:XP_008463322	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X4 [Cucumis melo].	41.30	293	166	2	2	292	47	335	3e-71	235
tr:A0A074WXY2_9PEZI	SubName: Full=FTHFS-domain-containing protein {ECO:0000313|EMBL:KEQ76374.1};	46.23	292	150	3	1	289	1	288	3e-71	247
rs:WP_038042690	methenyltetrahydrofolate cyclohydrolase [Thermus yunnanensis].	45.64	287	140	4	3	289	4	274	3e-71	233
tr:F6IE09_9SPHN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.77	291	141	4	5	293	21	302	3e-71	234
rs:WP_024925714	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Mesorhizobium].	45.39	293	150	5	4	292	3	289	3e-71	233
rs:WP_008062939	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. GM78].	46.18	288	147	3	2	289	3	282	3e-71	234
sp:FOLD_BRASB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.37	289	149	2	1	289	1	283	3e-71	233
sp:FOLD_RICAE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.69	295	161	3	4	297	3	287	3e-71	233
rs:WP_025961267	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB245a_519L21].	43.25	289	157	3	6	293	5	287	3e-71	234
rs:WP_043141911	methenyltetrahydrofolate cyclohydrolase [Ponticoccus sp. UMTAT08].	45.73	293	154	2	1	292	1	289	3e-71	234
sp:FOLD_RICTY	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.47	292	155	4	4	293	3	283	3e-71	233
rs:XP_006576275	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X2 [Glycine max].	43.30	291	159	2	5	293	72	358	3e-71	236
rs:WP_034433824	methenyltetrahydrofolate cyclohydrolase [Candidatus Contendobacter odensis].	43.99	291	157	2	2	292	3	287	3e-71	234
sp:FOLD_NEOSM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.30	287	142	5	4	287	3	277	3e-71	233
rs:WP_025781394	5,10-methylene-tetrahydrofolate cyclohydrolase [Candidatus Synechococcus spongiarum].	44.64	289	156	1	3	291	2	286	3e-71	234
rs:WP_014409178	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia montanensis].	41.36	295	162	3	4	297	3	287	3e-71	233
rs:XP_012534526	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Monomorium pharaonis].	45.61	296	153	3	3	292	28	321	3e-71	235
rs:WP_004751793	FolD 1 [Acinetobacter sp. ANC 3789].	46.15	286	146	3	5	290	14	291	3e-71	234
rs:WP_031119908	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	41.64	293	161	4	1	293	1	283	3e-71	233
rs:WP_003774275	methenyltetrahydrofolate cyclohydrolase [Erysipelothrix rhusiopathiae].	42.66	286	152	3	5	290	4	277	3e-71	233
rs:XP_007755967	formate-tetrahydrofolate ligase [Cladophialophora yegresii CBS 114405].	45.21	292	153	3	1	289	1	288	3e-71	247
rs:WP_030254185	methenyltetrahydrofolate cyclohydrolase [Streptomyces violens].	42.12	292	159	5	1	292	1	282	3e-71	233
sp:FOLD_CHLMU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.70	270	150	2	17	285	10	278	3e-71	233
rs:WP_010453016	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas fuscovaginae].	45.61	285	147	3	2	286	3	279	3e-71	233
sp:FOLD1_RUEPO	RecName: Full=Bifunctional protein FolD 1/3 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.55	292	152	2	1	292	1	285	4e-71	233
rs:WP_014377908	5,10-methylene-tetrahydrofolate dehydrogenase [Blastococcus saxobsidens].	43.05	295	157	4	1	295	1	284	4e-71	233
rs:WP_007796689	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium sp. CF122].	46.39	291	148	4	5	291	4	290	4e-71	233
rs:WP_025900664	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus].	43.25	289	157	3	6	293	5	287	4e-71	233
rs:WP_032138608	5,10-methylene-tetrahydrofolate cyclohydrolase [Rickettsia tamurae].	42.07	290	157	3	4	292	3	282	4e-71	233
sp:FOLD_SPHCR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.31	279	140	3	3	281	2	273	4e-71	234
rs:WP_014074657	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium sp. SYK-6].	49.47	285	138	3	6	289	7	286	4e-71	233
rs:WP_037886957	methenyltetrahydrofolate cyclohydrolase [Streptomyces viridochromogenes].	41.64	293	161	4	1	293	1	283	4e-71	233
sp:FOLD_CAUCN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.56	294	155	2	2	291	3	292	4e-71	233
sp:FOLD_PROM9	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.06	288	159	2	6	293	5	287	4e-71	233
rs:WP_044661414	methenyltetrahydrofolate cyclohydrolase [Sphingobium sp. YBL2].	48.08	287	144	2	3	289	4	285	4e-71	233
rs:WP_025668623	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. JGI 001013-F22].	45.73	293	151	4	4	292	3	291	4e-71	233
tr:A0A0D2AXR6_9EURO	SubName: Full=Strain CBS 89968 unplaced genomic scaffold supercont1.8, whole genome shotgun sequence {ECO:0000313|EMBL:KIW11245.1};	44.59	296	157	3	1	293	1	292	4e-71	247
rs:WP_039228641	methenyltetrahydrofolate cyclohydrolase [Clostridium haemolyticum].	42.65	279	149	2	6	284	5	272	4e-71	233
rs:WP_039616513	methenyltetrahydrofolate cyclohydrolase [Rhodobacteraceae bacterium PD-2].	45.73	293	154	2	1	292	1	289	4e-71	233
tr:V8BG41_STRPA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.40	289	142	3	5	293	26	304	4e-71	234
tr:A0A0D6NVC1_9PROT	SubName: Full=Bifunctional [5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase] {ECO:0000313|EMBL:GAN69613.1};	45.67	289	151	2	2	290	12	294	4e-71	233
sp:FOLD_PROM3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.01	284	152	2	6	286	5	284	4e-71	233
tr:F7F7I6_MONDO	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMODP00000013118}; Flags: Fragment;	48.28	261	128	3	3	257	30	289	4e-71	233
rs:WP_025826325	methenyltetrahydrofolate cyclohydrolase [Acetobacter persici].	45.67	289	151	2	2	290	14	296	4e-71	233
rs:WP_034156861	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. ERG5].	44.78	297	156	3	1	296	6	295	4e-71	233
rs:WP_013950098	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Hyphomicrobium].	45.42	284	149	2	1	284	1	278	4e-71	233
rs:WP_010487982	tetrahydrofolate dehydrogenase [Lactobacillus zeae].	44.98	289	148	3	6	294	5	282	4e-71	233
tr:L8PI49_STRVR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.64	293	161	4	1	293	4	286	4e-71	233
sp:FOLD2_SINMW	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.02	285	142	4	5	288	11	287	4e-71	233
rs:WP_029379558	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fuscovaginae].	47.00	283	142	3	6	288	11	285	4e-71	233
rs:WP_027035727	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium ciceri].	46.10	295	143	5	3	289	2	288	4e-71	233
rs:WP_013079769	5,10-methylene-tetrahydrofolate dehydrogenase [Caulobacter segnis].	45.58	294	152	2	2	291	3	292	4e-71	233
rs:WP_045559546	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. FxanaA7].	41.98	293	160	4	1	293	1	283	4e-71	233
rs:WP_036992694	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas pseudoalcaligenes].	47.52	282	140	4	4	285	8	281	4e-71	233
rs:WP_019055646	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces prunicolor].	42.32	293	159	4	1	293	1	283	4e-71	233
tr:H3CGS3_TETNG	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTNIP00000007451};	44.63	298	152	6	3	293	24	315	4e-71	234
rs:XP_003577993	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X1 [Brachypodium distachyon].	43.99	291	157	2	3	291	88	374	4e-71	236
rs:WP_043503477	methenyltetrahydrofolate cyclohydrolase [Streptomyces glaucescens].	41.30	293	162	4	1	293	1	283	4e-71	233
rs:WP_020280197	bifunctional protein folD [Lactobacillus otakiensis].	44.71	293	150	4	3	293	2	284	4e-71	233
rs:WP_014392256	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Rickettsia amblyommii].	41.69	295	161	3	4	297	3	287	4e-71	233
rs:WP_025059897	methenyltetrahydrofolate cyclohydrolase [Sulfitobacter donghicola].	46.42	293	152	2	1	292	1	289	4e-71	233
tr:X0PRE4_9LACO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.60	289	152	3	3	291	2	279	5e-71	233
rs:WP_020020615	hypothetical protein [alpha proteobacterium SCGC AAA160-J14].	45.52	290	149	4	4	289	6	290	5e-71	233
rs:WP_018544005	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. LaPpAH-108].	42.47	292	158	4	1	292	1	282	5e-71	233
rs:WP_007697318	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium sp. AP16].	45.08	295	154	4	2	292	3	293	5e-71	233
rs:WP_035452438	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus composti].	43.60	289	152	3	3	291	7	284	5e-71	233
rs:WP_007816773	5,10-methylene-tetrahydrofolate dehydrogenase [Roseobacter sp. AzwK-3b].	45.73	293	154	2	1	292	1	289	5e-71	233
rs:WP_037990490	methenyltetrahydrofolate cyclohydrolase [Thalassospira permensis].	44.14	290	156	2	3	292	4	287	5e-71	233
rs:WP_035568921	methenyltetrahydrofolate cyclohydrolase [Halomonas anticariensis].	48.48	297	132	8	4	293	12	294	5e-71	233
rs:WP_025958419	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB241_527L15].	43.25	289	157	3	6	293	5	287	5e-71	233
rs:WP_041577549	methenyltetrahydrofolate cyclohydrolase [Xanthobacter autotrophicus].	44.60	287	153	2	6	292	7	287	5e-71	233
rs:XP_010324898	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X4 [Solanum lycopersicum].	43.14	299	159	3	2	293	66	360	5e-71	235
rs:XP_001703554	5,10-methylenetetrahydrofolate dehydrogenase, partial [Chlamydomonas reinhardtii].	43.77	297	154	4	3	290	1	293	5e-71	233
rs:WP_045805805	5,10-methylene-tetrahydrofolate cyclohydrolase [Rickettsia argasii].	41.69	295	161	3	4	297	3	287	5e-71	233
rs:XP_008463321	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X3 [Cucumis melo].	41.30	293	166	2	2	292	65	353	5e-71	235
rs:WP_033311484	methenyltetrahydrofolate cyclohydrolase [Streptomyces iakyrus].	41.98	293	160	4	1	293	1	283	5e-71	233
rs:WP_022070543	bifunctional protein FolD [Fusobacterium sp. CAG:649].	44.60	287	147	4	5	290	2	277	5e-71	233
rs:WP_003570270	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium leguminosarum].	46.58	292	148	4	5	292	4	291	5e-71	233
rs:WP_027888684	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Meiothermus].	44.95	287	146	5	6	291	4	279	5e-71	233
rs:WP_035021862	5,10-methylene-tetrahydrofolate cyclohydrolase [Carnobacterium sp. WN1374].	44.67	291	150	3	1	291	1	280	5e-71	233
rs:WP_032522621	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus marinus].	42.36	288	161	2	6	293	5	287	5e-71	233
rs:WP_046840684	5,10-methylene-tetrahydrofolate cyclohydrolase [Candidatus Synechococcus spongiarum].	44.79	288	155	1	3	290	2	285	5e-71	233
rs:WP_016926259	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia conorii].	41.69	295	161	3	4	297	3	287	5e-71	233
rs:WP_019361010	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas fuscovaginae].	45.26	285	148	3	2	286	3	279	5e-71	233
tr:A7IMR5_XANP2	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.60	287	153	2	6	292	11	291	5e-71	233
tr:I1C7A6_RHIO9	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EIE84336.1};	49.78	225	107	2	68	290	2	222	5e-71	231
rs:WP_015397614	methylenetetrahydrofolate dehydrogenase [Bartonella australis].	44.93	296	151	5	3	292	2	291	5e-71	233
tr:A0A0C6G0G8_STRPY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.56	246	119	2	49	294	1	236	5e-71	231
tr:K9KES3_HORSE	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like protein {ECO:0000313|EMBL:AEQ01004.1}; Flags: Fragment;	53.71	229	99	3	73	295	10	237	5e-71	231
sp:FOLD_MARMM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.36	291	152	4	1	289	1	286	5e-71	233
rs:XP_007734178	C-1-tetrahydrofolate synthase, mitochondrial [Capronia epimyces CBS 606.96].	45.89	292	151	3	1	289	1	288	5e-71	247
rs:XP_007295962	putative C-1-tetrahydrofolate synthase [Marssonina brunnea f. sp. 'multigermtubi' MB_m1].	44.78	297	153	5	1	292	117	407	5e-71	236
rs:XP_012029055	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Ovis aries].	46.10	295	111	4	3	291	65	317	5e-71	234
rs:XP_008463319	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X2 [Cucumis melo].	41.30	293	166	2	2	292	73	361	5e-71	235
rs:WP_014284529	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudovibrio sp. FO-BEG1].	44.71	293	156	3	2	293	3	290	5e-71	233
rs:WP_042459837	methenyltetrahydrofolate cyclohydrolase [Rhodovulum sulfidophilum].	44.03	293	159	2	1	292	1	289	5e-71	233
rs:WP_030671505	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	41.98	293	160	4	1	293	1	283	5e-71	233
rs:XP_003683892	hypothetical protein TPHA_0A03820 [Tetrapisispora phaffii CBS 4417].	44.83	290	153	3	4	290	30	315	6e-71	247
rs:WP_039183946	methenyltetrahydrofolate cyclohydrolase [Leisingera sp. ANG-M7].	46.23	292	150	3	1	292	1	285	6e-71	233
rs:WP_025952899	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB243_495P20].	43.25	289	157	3	6	293	5	287	6e-71	233
rs:WP_029641339	methenyltetrahydrofolate cyclohydrolase [alpha proteobacterium Mf 1.05b.01].	45.99	287	147	4	6	289	7	288	6e-71	233
rs:WP_021295663	hypothetical protein [Alicyclobacillus acidoterrestris].	45.49	288	145	3	3	290	2	277	6e-71	233
rs:WP_009869571	5,10-methylene-tetrahydrofolate dehydrogenase [Magnetospirillum magnetotacticum].	45.67	289	151	2	3	291	4	286	6e-71	233
rs:WP_038004443	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Thalassobacter].	46.39	291	151	2	3	292	2	288	6e-71	233
rs:WP_037119663	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. CF097].	45.89	292	148	5	5	291	4	290	6e-71	233
rs:WP_022694102	5,10-methylene-tetrahydrofolate dehydrogenase [Ponticaulis koreensis].	46.37	289	147	4	5	290	4	287	6e-71	233
sp:FOLD_MAGSA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.67	289	151	2	3	291	4	286	6e-71	233
rs:WP_010393482	5,10-methylene-tetrahydrofolate dehydrogenase [Paracoccus sp. TRP].	46.96	296	140	6	1	291	1	284	6e-71	233
sp:FOLD_LACH4	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.20	281	142	3	3	283	2	270	6e-71	232
rs:XP_003664487	hypothetical protein MYCTH_2307368 [Myceliophthora thermophila ATCC 42464].	44.93	296	156	3	1	293	1	292	6e-71	246
rs:WP_009423710	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium sp. oral taxon 370].	44.64	289	148	4	5	292	2	279	6e-71	232
rs:WP_006041745	methenyltetrahydrofolate cyclohydrolase [Synechococcus sp. WH 7805].	45.58	283	144	3	6	288	5	277	6e-71	233
rs:WP_025549346	methenyltetrahydrofolate cyclohydrolase [Sphingobium sp. KK22].	47.74	287	145	2	3	289	4	285	6e-71	233
tr:V4NIH6_9CAUL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.92	292	144	4	3	288	12	298	6e-71	233
rs:WP_007503650	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces zinciresistens].	41.64	293	161	4	1	293	1	283	6e-71	232
rs:WP_043225941	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5193].	43.71	286	151	4	1	286	1	276	6e-71	232
rs:WP_028714549	methenyltetrahydrofolate cyclohydrolase [Paracoccus sp. J55].	45.49	288	150	2	5	292	9	289	7e-71	233
tr:A0A0D6P669_9PROT	SubName: Full=Bifunctional [5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase] {ECO:0000313|EMBL:GAN77255.1};	44.79	288	153	2	3	290	15	296	7e-71	233
rs:WP_025928500	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB243_495G23].	42.91	289	158	3	6	293	5	287	7e-71	233
rs:WP_029742838	methenyltetrahydrofolate cyclohydrolase [Ensifer sp. JGI 0001011-A08].	43.79	290	155	3	6	295	9	290	7e-71	233
rs:WP_026242575	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	42.61	291	157	5	1	291	1	281	7e-71	233
rs:WP_018992435	hypothetical protein [Azoarcus toluclasticus].	44.18	292	157	2	1	292	1	286	7e-71	233
rs:XP_006444280	hypothetical protein CICLE_v10021378mg [Citrus clementina].	47.33	262	132	2	34	293	3	260	7e-71	231
rs:WP_007825001	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium sp. CF142].	45.55	292	151	4	5	292	4	291	7e-71	233
rs:WP_028092302	methenyltetrahydrofolate cyclohydrolase [Donghicola xiamenensis].	45.55	292	150	2	1	292	1	283	7e-71	233
rs:WP_003624830	5,10-methylene-tetrahydrofolate dehydrogenase [Acetobacter pasteurianus].	46.02	289	150	2	2	290	14	296	7e-71	233
rs:WP_014410710	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia parkeri].	41.69	295	161	3	4	297	3	287	7e-71	232
rs:WP_025012426	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus].	44.98	289	148	3	6	294	5	282	7e-71	232
tr:A0A075H8E2_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.53	288	134	6	1	288	1	268	7e-71	232
rs:WP_030449339	methenyltetrahydrofolate cyclohydrolase [Actinocatenispora sera].	40.75	292	167	4	2	293	4	289	7e-71	232
rs:WP_027531677	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. WSM3983].	47.06	289	146	3	3	291	2	283	7e-71	233
rs:WP_005481066	folD protein [Streptomyces bottropensis].	42.12	292	159	4	1	292	1	282	7e-71	232
rs:WP_016747191	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas wittichii].	46.90	290	147	3	3	292	2	284	7e-71	233
rs:XP_506064	YALI0F30745p [Yarrowia lipolytica].	45.24	294	154	3	2	292	67	356	8e-71	246
rs:WP_029017401	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [unclassified Actinobacteria (miscellaneous)].	44.33	291	151	5	1	291	1	280	8e-71	232
rs:WP_041848836	methenyltetrahydrofolate cyclohydrolase [Bartonella bacilliformis].	46.44	295	146	5	5	293	4	292	8e-71	233
rs:WP_003584295	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium leguminosarum].	46.58	292	148	4	5	292	4	291	8e-71	233
tr:B6TJF9_MAIZE	SubName: Full=FolD bifunctional protein {ECO:0000313|EMBL:ACG37242.1};	44.52	292	156	2	2	291	98	385	8e-71	236
rs:WP_037161678	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Rhizobium].	45.92	294	151	4	3	292	2	291	8e-71	233
rs:WP_004788958	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira meyeri].	40.48	294	161	3	2	295	3	282	8e-71	232
rs:WP_041789477	methenyltetrahydrofolate cyclohydrolase [Rhodomicrobium vannielii].	49.42	259	125	2	31	289	21	273	8e-71	232
rs:WP_030953030	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5140].	42.32	293	159	4	1	293	1	283	8e-71	232
rs:WP_008003695	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. GM49].	46.18	288	147	3	2	289	3	282	8e-71	233
rs:WP_016945682	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia conorii].	41.69	295	161	3	4	297	3	287	8e-71	232
rs:WP_046383919	methenyltetrahydrofolate cyclohydrolase [Pseudomonas veronii].	45.52	290	149	4	1	289	1	282	8e-71	233
rs:WP_018115112	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium sp. JGI 0001005-K05].	47.10	293	145	6	5	292	4	291	8e-71	233
rs:XP_009470753	PREDICTED: LOW QUALITY PROTEIN: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Nipponia nippon].	44.82	299	117	4	3	295	3	259	8e-71	231
sp:FOLD_RICBR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.56	289	153	4	4	290	3	280	8e-71	232
rs:XP_012435937	PREDICTED: bifunctional protein FolD 2 isoform X2 [Gossypium raimondii].	48.35	242	119	2	54	293	2	239	8e-71	231
rs:XP_005978170	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Pantholops hodgsonii].	45.39	293	150	5	4	292	3	289	8e-71	232
rs:WP_030345602	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-1022].	41.44	292	161	4	1	292	1	282	8e-71	232
rs:WP_012854523	5,10-methylene-tetrahydrofolate dehydrogenase [Thermomonospora curvata].	44.68	282	145	4	1	282	1	271	9e-71	232
rs:WP_006821417	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium casei].	43.64	291	150	4	1	291	1	277	9e-71	232
sp:FOLD_BARBK	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.10	295	147	5	5	293	4	292	9e-71	233
rs:WP_025944742	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB241_529C4].	42.36	288	161	2	6	293	5	287	9e-71	233
rs:WP_025893383	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB241_527N11].	42.91	289	158	3	6	293	5	287	9e-71	233
rs:WP_012812368	5,10-methylene-tetrahydrofolate dehydrogenase [Acetobacter pasteurianus].	46.02	289	150	2	2	290	14	296	9e-71	233
rs:WP_003376964	MULTISPECIES: tetrahydrofolate dehydrogenase [Clostridium].	42.65	279	149	2	6	284	5	272	9e-71	232
rs:WP_025659516	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Rhizobium].	45.55	292	151	4	5	292	4	291	9e-71	233
rs:XP_002554103	KLTH0E14366p [Lachancea thermotolerans].	44.26	296	158	3	1	293	31	322	9e-71	246
rs:WP_018528471	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. HmicA12].	42.12	292	159	5	1	292	1	282	9e-71	232
rs:WP_037407465	methenyltetrahydrofolate cyclohydrolase [Shinella sp. DD12].	47.40	289	142	6	5	291	11	291	9e-71	232
rs:WP_025881681	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB241_527E14].	42.91	289	158	3	6	293	5	287	9e-71	232
rs:WP_023923641	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodobacter capsulatus].	46.92	292	148	3	1	292	1	285	9e-71	232
rs:WP_025942960	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB245a_521O23].	42.91	289	158	3	6	293	5	287	9e-71	232
tr:A0A068S5Z5_9FUNG	SubName: Full=Fthfs-domain-containing protein {ECO:0000313|EMBL:CDH56671.1};	45.21	292	153	3	5	293	2	289	9e-71	246
rs:WP_031516354	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5123].	42.96	284	152	5	1	284	1	274	9e-71	232
tr:A0A081MT80_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.92	294	151	4	3	292	9	298	1e-70	233
rs:WP_033935182	methenyltetrahydrofolate cyclohydrolase [Lactobacillus mucosae].	44.18	292	150	5	3	292	2	282	1e-70	232
rs:WP_015663438	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobium oligotrophicum].	46.37	289	149	2	1	289	1	283	1e-70	232
rs:WP_033325364	methenyltetrahydrofolate cyclohydrolase [Streptomyces yerevanensis].	42.32	293	159	4	1	293	1	283	1e-70	232
tr:J7RNK0_KAZNA	SubName: Full=KNAG0G00770 protein {ECO:0000313|EMBL:CCK71133.1};	45.07	304	155	4	2	297	3	302	1e-70	246
rs:WP_023915561	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodobacter capsulatus].	46.92	292	148	3	1	292	1	285	1e-70	232
rs:WP_016642647	bifunctional protein FolD [Streptomyces aurantiacus].	42.27	291	158	4	1	291	1	281	1e-70	232
rs:WP_037222997	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. YR060].	45.08	295	154	4	2	292	3	293	1e-70	232
rs:XP_010242784	PREDICTED: bifunctional protein FolD 2 isoform X2 [Nelumbo nucifera].	48.35	242	119	2	54	293	2	239	1e-70	230
rs:WP_020131105	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. 303MFCol5.2].	41.30	293	162	4	1	293	1	283	1e-70	232
tr:A0A0A9PJX0_ARUDO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:JAF21615.1};	43.62	298	162	2	2	297	93	386	1e-70	235
rs:WP_025926654	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB241_528J8].	42.71	288	160	2	6	293	5	287	1e-70	232
tr:S9Q6E8_SCHOY	SubName: Full=6,7,8-tetrahydrofolate synthase {ECO:0000313|EMBL:EPX75208.1};	44.48	290	154	3	3	289	2	287	1e-70	246
tr:W0VM95_ZYGBA	SubName: Full=Probable C-1-tetrahydrofolate synthase,mitochondrial {ECO:0000313|EMBL:CDH11070.1};	44.78	297	157	3	4	297	18	310	1e-70	246
tr:A0A021XAL0_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.40	289	142	6	5	291	9	289	1e-70	232
rs:WP_039218547	methenyltetrahydrofolate cyclohydrolase [Clostridium novyi].	43.37	279	147	2	6	284	5	272	1e-70	231
rs:WP_024921115	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Afipia].	46.37	289	149	2	1	289	1	283	1e-70	232
rs:XP_012729729	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Fundulus heteroclitus].	44.41	295	153	5	3	291	24	313	1e-70	233
rs:XP_001780302	predicted protein, partial [Physcomitrella patens].	43.06	288	158	2	6	291	1	284	1e-70	233
rs:WP_005971145	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium periodonticum].	44.60	287	147	4	5	290	2	277	1e-70	232
rs:WP_035025594	methenyltetrahydrofolate cyclohydrolase [Enterovibrio calviensis].	45.14	288	151	2	4	291	12	292	1e-70	232
rs:WP_047167294	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. Y57].	47.40	289	147	2	3	291	6	289	1e-70	232
rs:XP_007477943	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Monodelphis domestica].	48.28	261	128	3	3	257	38	297	1e-70	233
rs:WP_022131991	bifunctional protein FolD [Clostridium sp. CAG:242].	48.10	289	139	4	3	291	2	279	1e-70	232
rs:WP_022084364	5,10-methylene-tetrahydrofolate dehydrogenase [Mycoplasma sp. CAG:611].	43.90	287	146	3	4	290	2	273	1e-70	231
rs:WP_037248662	methenyltetrahydrofolate cyclohydrolase [Roseovarius sp. MCTG156(2b)].	45.58	294	149	3	1	292	1	285	1e-70	232
tr:S2KZ23_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.48	297	132	8	4	293	25	307	1e-70	233
tr:A0A0D5MI46_LACHE	SubName: Full=5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:AJY61273.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AJY61273.1}; EC=3.5.4.9 {ECO:0000313|EMBL:AJY61273.1};	45.20	281	142	3	3	283	2	270	1e-70	231
rs:WP_007089153	5,10-methylene-tetrahydrofolate dehydrogenase [Thalassospira xiamenensis].	43.79	290	157	2	3	292	4	287	1e-70	232
rs:WP_035065915	5,10-methylene-tetrahydrofolate cyclohydrolase [Carnobacterium maltaromaticum].	44.10	288	150	3	6	293	1	277	1e-70	231
rs:WP_020398415	hypothetical protein [Kordiimonas gwangyangensis].	46.90	290	149	2	4	292	8	293	1e-70	232
rs:WP_027263472	methenyltetrahydrofolate cyclohydrolase [Sedimentitalea nanhaiensis].	46.05	291	151	2	1	291	1	285	1e-70	232
tr:A0A061MU49_AGRRH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.75	295	155	4	2	292	6	296	1e-70	232
rs:WP_020055862	hypothetical protein, partial [alpha proteobacterium SCGC AAA015-O19].	46.24	279	144	2	1	279	1	273	1e-70	231
rs:WP_033294679	5,10-methylene-tetrahydrofolate cyclohydrolase [Amycolatopsis jejuensis].	45.21	292	144	5	1	292	1	276	1e-70	231
rs:WP_022731676	5,10-methylene-tetrahydrofolate dehydrogenase [Thalassospira lucentensis].	43.79	290	157	2	3	292	4	287	1e-70	232
rs:WP_037156437	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. CF258].	46.58	292	146	5	5	291	4	290	1e-70	232
sp:FOLD_RICPU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.36	295	162	3	4	297	3	287	1e-70	232
rs:WP_018244838	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium].	45.89	292	150	4	5	292	4	291	1e-70	232
rs:WP_005977877	5,10-methylene-tetrahydrofolate dehydrogenase [Ruegeria lacuscaerulensis].	44.86	292	154	2	1	292	1	285	1e-70	232
rs:WP_007819349	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium sp. CF142].	45.39	293	152	4	4	292	3	291	1e-70	232
sp:FOLD_BRASO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.02	289	150	2	1	289	1	283	1e-70	232
rs:WP_025317521	methenyltetrahydrofolate cyclohydrolase [Spiroplasma mirum].	42.66	286	154	2	1	286	1	276	1e-70	231
tr:N1PVG9_DOTSN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EME46938.1};	44.86	292	154	3	1	289	1	288	1e-70	246
tr:E3I451_RHOVT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.42	259	125	2	31	289	39	291	1e-70	232
rs:WP_035430497	methenyltetrahydrofolate cyclohydrolase [Asticcacaulis sp. AC466].	46.90	290	143	4	5	288	1	285	1e-70	232
rs:WP_006722240	methenyltetrahydrofolate cyclohydrolase [Collinsella intestinalis].	47.93	290	138	5	3	290	2	280	1e-70	232
rs:WP_027263898	methenyltetrahydrofolate cyclohydrolase [Sedimentitalea nanhaiensis].	46.05	291	151	2	1	291	1	285	1e-70	232
tr:A0A093T3Z9_PHACA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFW89409.1}; Flags: Fragment;	52.54	236	105	3	62	291	1	235	1e-70	230
rs:WP_019171097	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudaminobacter salicylatoxidans].	45.58	294	150	5	3	292	2	289	1e-70	232
rs:WP_022381849	bifunctional protein FolD [Dialister sp. CAG:357].	44.71	293	150	3	1	293	1	281	1e-70	231
rs:WP_042473102	methenyltetrahydrofolate cyclohydrolase [Agrobacterium rhizogenes].	44.75	295	155	4	2	292	3	293	1e-70	232
rs:WP_013848697	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium chlorophenolicum].	48.08	287	144	2	3	289	4	285	1e-70	232
rs:WP_008792378	5,10-methylene-tetrahydrofolate dehydrogenase [Coprobacillus sp. 8_2_54BFAA].	48.25	286	134	5	5	288	2	275	1e-70	231
rs:WP_029912449	methenyltetrahydrofolate cyclohydrolase [Caulobacter sp. UNC358MFTsu5.1].	44.71	293	154	2	3	291	4	292	1e-70	232
tr:A0A0E0CE16_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI02G00920.4};	45.02	291	147	3	3	291	79	358	1e-70	234
rs:XP_008463318	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X1 [Cucumis melo].	41.30	293	166	2	2	292	94	382	1e-70	235
rs:WP_040473257	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus gigeriorum].	43.06	288	152	3	4	291	3	278	1e-70	231
rs:WP_026283000	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. 2MFCol3.1].	45.58	294	152	4	3	292	2	291	1e-70	232
rs:WP_030089590	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. DC-6].	46.90	290	147	3	3	292	2	284	1e-70	232
rs:WP_029994387	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. YL-JM2C].	46.90	290	147	3	3	292	2	284	1e-70	232
rs:WP_003869840	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Thermoanaerobacter].	41.18	289	154	5	5	293	2	274	1e-70	231
rs:WP_007124365	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus antri].	45.61	285	140	6	5	286	2	274	1e-70	232
rs:WP_004948580	FolD 1 [Acinetobacter soli].	47.77	291	141	6	2	290	10	291	1e-70	232
tr:D3T8S2_THEIA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.93	293	160	4	1	293	1	277	1e-70	231
rs:XP_004956595	PREDICTED: bifunctional protein FolD 2-like [Setaria italica].	43.84	292	158	2	2	291	95	382	1e-70	235
rs:WP_010038569	5,10-methylene-tetrahydrofolate dehydrogenase [Gemmata obscuriglobus].	44.59	296	151	3	1	291	1	288	1e-70	232
rs:WP_029011685	methenyltetrahydrofolate cyclohydrolase [Niveispirillum irakense].	44.90	294	154	2	3	292	4	293	1e-70	232
rs:WP_019996237	hypothetical protein [Aureimonas ureilytica].	46.80	297	148	5	1	292	1	292	1e-70	232
rs:WP_030688517	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL B-1347].	42.81	292	157	5	1	292	1	282	1e-70	231
rs:WP_020135701	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. 351MFTsu5.1].	41.30	293	162	4	1	293	1	283	1e-70	231
rs:WP_013046743	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Puniceispirillum marinum].	44.86	292	156	2	1	291	1	288	1e-70	232
rs:WP_028215537	methenyltetrahydrofolate cyclohydrolase [Burkholderia mimosarum].	45.89	292	148	5	2	292	3	285	1e-70	232
rs:WP_046817534	methenyltetrahydrofolate cyclohydrolase [Pseudomonas putida].	47.37	285	142	3	6	290	15	291	1e-70	232
rs:WP_020800973	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas].	46.18	288	147	3	2	289	3	282	1e-70	232
rs:WP_043868019	methenyltetrahydrofolate cyclohydrolase [Celeribacter indicus].	44.86	292	154	2	1	292	1	285	1e-70	232
rs:XP_002982530	hypothetical protein SELMODRAFT_116671 [Selaginella moellendorffii].	41.87	289	161	3	6	291	1	285	1e-70	232
rs:WP_019527880	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	41.30	293	162	4	1	293	1	283	1e-70	231
rs:WP_038471496	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Mollicutes bacterium HR1].	42.91	282	150	2	5	286	2	272	1e-70	231
rs:WP_043443187	methenyltetrahydrofolate cyclohydrolase [Streptomyces nodosus].	42.32	293	159	4	1	293	1	283	1e-70	231
rs:WP_003616926	5,10-methylene-tetrahydrofolate dehydrogenase [Komagataeibacter hansenii].	45.36	291	153	2	3	293	17	301	2e-70	232
rs:WP_005605295	tetrahydrofolate dehydrogenase [Granulicatella adiacens].	45.99	287	144	4	4	290	3	278	2e-70	231
tr:A0A077C0C7_9RICK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.27	293	169	2	1	293	1	287	2e-70	231
rs:WP_030003845	bifunctional protein FolD [Acholeplasma palmae].	44.88	283	141	4	5	287	3	270	2e-70	231
rs:WP_007627988	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium sp. CCGE 510].	45.92	294	151	4	3	292	2	291	2e-70	232
rs:WP_027821407	bifunctional protein FolD [Lactobacillus plantarum].	46.74	291	142	5	4	292	3	282	2e-70	231
rs:WP_039683377	methenyltetrahydrofolate cyclohydrolase [Tateyamaria sp. ANG-S1].	44.37	293	158	2	1	292	1	289	2e-70	232
rs:WP_019219812	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella sp. R4(2010)].	44.52	292	154	4	5	292	4	291	2e-70	232
rs:XP_002498549	ZYRO0G12936p [Zygosaccharomyces rouxii].	45.36	291	152	3	6	293	20	306	2e-70	245
rs:WP_014726516	5,10-methylene-tetrahydrofolate dehydrogenase [Blattabacterium sp. (Blaberus giganteus)].	40.34	290	165	3	1	289	1	283	2e-70	231
rs:WP_023915743	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodobacter capsulatus].	46.92	292	148	3	1	292	1	285	2e-70	232
rs:WP_037734036	methenyltetrahydrofolate cyclohydrolase [Streptomyces mirabilis].	40.41	292	164	3	1	292	1	282	2e-70	231
rs:WP_027038925	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium ciceri].	45.21	292	153	2	1	292	1	285	2e-70	232
sp:FOLD_RICAH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.55	296	156	3	4	292	3	288	2e-70	231
rs:WP_028232470	methenyltetrahydrofolate cyclohydrolase [Burkholderia mimosarum].	45.89	292	148	5	2	292	3	285	2e-70	232
rs:XP_005850778	hypothetical protein CHLNCDRAFT_48501 [Chlorella variabilis].	43.69	293	145	4	3	293	2	276	2e-70	231
rs:WP_030317093	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL B-3229].	41.30	293	162	4	1	293	1	283	2e-70	231
rs:WP_045799636	5,10-methylene-tetrahydrofolate cyclohydrolase [Rickettsia bellii].	42.56	289	153	4	4	290	3	280	2e-70	231
rs:WP_032516703	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus marinus].	42.36	288	161	2	6	293	5	287	2e-70	232
sp:FOLD_RICB8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.56	289	153	4	4	290	3	280	2e-70	231
rs:WP_034449503	bifunctional protein FolD [Bartonella quintana].	46.60	294	145	5	4	291	3	290	2e-70	232
rs:WP_035262558	methenyltetrahydrofolate cyclohydrolase [Actibacterium mucosum].	44.18	292	159	1	1	292	1	288	2e-70	232
rs:XP_006564486	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Apis mellifera].	44.78	297	155	4	2	292	27	320	2e-70	233
tr:A0A0D2C1S7_9EURO	SubName: Full=Strain CBS 72588 unplaced genomic scaffold supercont1.4, whole genome shotgun sequence {ECO:0000313|EMBL:KIW43677.1};	45.21	292	153	3	1	289	91	378	2e-70	246
rs:WP_038446613	methenyltetrahydrofolate cyclohydrolase [Bdellovibrio bacteriovorus].	43.42	281	149	2	5	285	3	273	2e-70	231
rs:WP_038708917	methenyltetrahydrofolate cyclohydrolase [Burkholderia sp. lig30].	48.41	283	138	3	3	285	4	278	2e-70	231
rs:WP_028713924	methenyltetrahydrofolate cyclohydrolase [Paracoccus sp. J55].	45.14	288	151	2	5	292	1	281	2e-70	231
rs:WP_013725466	tetrahydrofolate dehydrogenase [Clostridium botulinum].	43.21	280	146	4	6	284	5	272	2e-70	231
rs:WP_027685962	methenyltetrahydrofolate cyclohydrolase [Rhizobium leguminosarum].	45.89	292	150	4	5	292	4	291	2e-70	232
rs:WP_004396359	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Thermoanaerobacter].	41.18	289	154	5	5	293	2	274	2e-70	231
rs:WP_040024399	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. 150FB].	41.98	293	160	5	1	293	1	283	2e-70	231
rs:WP_030961032	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-378].	42.81	292	157	5	1	292	1	282	2e-70	231
tr:A0A088TKU7_9MOLU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.91	282	150	2	5	286	2	272	2e-70	231
rs:WP_043774226	methenyltetrahydrofolate cyclohydrolase [Roseivivax isoporae].	45.21	292	154	2	1	292	1	286	2e-70	231
rs:WP_033272374	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Actinomycetales].	41.30	293	162	4	1	293	1	283	2e-70	231
rs:WP_037694339	methenyltetrahydrofolate cyclohydrolase [Streptomyces scabiei].	41.98	293	160	4	1	293	1	283	2e-70	231
rs:XP_008866173	hypothetical protein H310_03884 [Aphanomyces invadans].	46.58	292	148	3	5	292	4	291	2e-70	231
rs:WP_019479926	methenyltetrahydrofolate cyclohydrolase [Prochlorococcus sp. W11].	42.31	286	160	2	6	291	5	285	2e-70	231
tr:W2Z3D1_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETP41580.1};	40.59	303	166	4	1	293	1	299	2e-70	232
rs:WP_003534969	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Erysipelotrichaceae].	48.25	286	134	5	5	288	2	275	2e-70	231
rs:WP_045776734	methenyltetrahydrofolate cyclohydrolase [Elstera litoralis].	43.86	285	151	3	6	290	14	289	2e-70	231
rs:XP_009500003	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Phalacrocorax carbo].	51.88	239	108	3	63	295	1	238	2e-70	230
rs:WP_030871281	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-37].	40.61	293	164	4	1	293	1	283	2e-70	231
rs:WP_006116793	5,10-methylene-tetrahydrofolate dehydrogenase [Acetobacter pomorum].	46.02	289	150	2	2	290	14	296	2e-70	232
rs:WP_031180786	methenyltetrahydrofolate cyclohydrolase [Streptomyces seoulensis].	42.27	291	158	4	1	291	1	281	2e-70	231
rs:WP_010919099	5,10-methylene-tetrahydrofolate dehydrogenase [Caulobacter vibrioides].	44.56	294	155	2	2	291	50	339	2e-70	233
rs:WP_030750036	methenyltetrahydrofolate cyclohydrolase [Streptomyces griseus].	44.41	286	149	4	1	286	1	276	2e-70	231
rs:WP_029941441	methenyltetrahydrofolate cyclohydrolase [Sphingomonas astaxanthinifaciens].	48.29	292	145	3	1	291	1	287	2e-70	231
rs:WP_003554258	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus brevis].	43.20	294	155	4	3	294	2	285	2e-70	231
rs:WP_019205837	hypothetical protein [Lactobacillus ingluviei].	45.10	286	144	4	3	286	2	276	2e-70	231
rs:WP_009030584	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobium sp. ORS 375].	46.37	289	149	2	1	289	1	283	2e-70	231
tr:A0A0D2FX00_9EURO	SubName: Full=Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.3, whole genome shotgun sequence {ECO:0000313|EMBL:KIX06857.1};	45.73	293	150	4	1	289	1	288	2e-70	245
rs:WP_024311513	methenyltetrahydrofolate cyclohydrolase [Sinorhizobium medicae].	46.67	285	143	4	5	288	11	287	2e-70	231
rs:WP_015338835	bifunctional protein FolD [Rhizobium tropici].	45.21	292	152	4	5	292	4	291	2e-70	231
rs:WP_026845656	5,10-methylene-tetrahydrofolate cyclohydrolase [Geodermatophilaceae bacterium URHA0031].	45.33	289	147	2	1	289	1	278	2e-70	231
tr:S6C8A4_LACCA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.98	289	148	3	6	294	19	296	2e-70	231
rs:WP_025965636	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB243_496M6].	43.55	287	155	3	6	291	5	285	2e-70	231
rs:WP_046585817	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. MUSC149T].	41.30	293	162	4	1	293	1	283	2e-70	231
rs:WP_020941767	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces collinus].	41.10	292	162	4	1	292	1	282	2e-70	231
rs:WP_042995304	methenyltetrahydrofolate cyclohydrolase [Bartonella quintana].	46.60	294	145	5	4	291	3	290	2e-70	231
rs:WP_029964437	methenyltetrahydrofolate cyclohydrolase [Ensifer sp. USDA 6670].	46.10	295	149	6	3	292	2	291	2e-70	231
rs:WP_028295197	methenyltetrahydrofolate cyclohydrolase [Oceanobacter kriegii].	44.71	293	156	2	1	291	1	289	2e-70	231
rs:WP_020953196	methylenetetrahydrofolate dehydrogenase [Paracoccus aminophilus].	46.37	289	147	3	4	292	2	282	2e-70	231
rs:WP_025437169	methenyltetrahydrofolate cyclohydrolase [Komagataeibacter xylinus].	44.33	291	154	3	1	290	6	289	2e-70	231
rs:WP_030360718	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	42.31	286	155	4	1	286	1	276	2e-70	231
rs:WP_033528736	methenyltetrahydrofolate cyclohydrolase [Streptomyces galbus].	41.78	292	160	4	1	292	1	282	2e-70	231
sp:FOLD_METMJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.39	287	135	7	5	290	2	273	2e-70	231
rs:WP_037212725	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. YR295].	46.58	292	146	5	5	291	4	290	2e-70	231
rs:WP_003994756	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces viridochromogenes].	41.44	292	161	3	1	292	1	282	2e-70	231
rs:WP_046914184	methenyltetrahydrofolate cyclohydrolase [Streptomyces stelliscabiei].	41.78	292	160	4	1	292	1	282	2e-70	231
rs:WP_025888609	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB241_526B17].	42.91	289	158	3	6	293	5	287	2e-70	231
sp:FOLD_METPE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	47.04	287	135	5	5	290	2	272	2e-70	231
rs:WP_038655326	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium huakuii].	47.10	293	145	5	4	291	3	290	2e-70	231
rs:WP_022404134	bifunctional protein FolD [Anaerotruncus sp. CAG:390].	46.71	289	144	2	3	291	2	280	2e-70	231
rs:WP_046261552	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. WM6386].	41.78	292	160	4	1	292	1	282	2e-70	231
rs:WP_027836974	methenyltetrahydrofolate cyclohydrolase [Mastigocoleus testarum].	47.95	292	140	5	1	289	1	283	2e-70	231
rs:WP_031803571	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas aeruginosa].	47.64	254	123	2	1	254	1	244	2e-70	229
sp:FOLD1_SPHWW	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.90	290	147	3	3	292	2	284	2e-70	231
rs:WP_024883289	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. CNH189].	40.96	293	163	4	1	293	1	283	2e-70	231
tr:A0A0D3H5B0_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART09G05630.2};	44.33	291	156	2	2	290	17	303	2e-70	232
rs:WP_010468445	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces somaliensis].	41.78	292	160	5	1	292	1	282	2e-70	231
rs:XP_005957141	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Pantholops hodgsonii].	44.37	293	155	2	3	291	4	292	2e-70	234
rs:WP_037587375	methenyltetrahydrofolate cyclohydrolase [Staphylococcus aureus].	42.76	290	155	3	1	290	1	279	2e-70	231
rs:WP_009465123	5,10-methylene-tetrahydrofolate dehydrogenase [Ahrensia sp. R2A130].	45.51	301	144	5	3	292	2	293	2e-70	231
rs:WP_047106294	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus casei].	44.64	289	149	3	6	294	5	282	3e-70	231
rs:WP_037798063	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. Mg1].	42.81	292	157	5	1	292	1	282	3e-70	231
rs:WP_030351530	methenyltetrahydrofolate cyclohydrolase [Streptomyces scopuliridis].	42.32	293	159	4	1	293	1	283	3e-70	231
rs:WP_025946856	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB241_528N20].	42.91	289	158	3	6	293	5	287	3e-70	231
rs:WP_034552920	5,10-methylene-tetrahydrofolate cyclohydrolase [Carnobacterium funditum].	42.71	288	154	3	6	293	1	277	3e-70	231
rs:XP_001769729	predicted protein, partial [Physcomitrella patens].	42.71	288	159	2	6	291	1	284	3e-70	231
rs:XP_010419614	PREDICTED: bifunctional protein FolD 4, chloroplastic-like isoform X1 [Camelina sativa].	44.93	296	154	4	2	292	68	359	3e-70	233
rs:WP_046814346	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus helveticus].	44.84	281	143	3	3	283	2	270	3e-70	231
rs:WP_018324208	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium giardinii].	45.55	292	149	5	5	291	4	290	3e-70	231
rs:WP_029002353	methenyltetrahydrofolate cyclohydrolase [Azorhizobium doebereinerae].	43.90	287	155	2	6	292	7	287	3e-70	231
rs:WP_017669526	5,10-methylene-tetrahydrofolate dehydrogenase [Blastomonas sp. AAP53].	45.70	291	153	2	1	291	1	286	3e-70	231
rs:WP_029129795	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	42.47	292	162	4	1	292	1	286	3e-70	231
rs:WP_028914004	methenyltetrahydrofolate cyclohydrolase [Pseudorhodobacter ferrugineus].	46.26	294	147	3	1	292	1	285	3e-70	231
rs:WP_018010525	5,10-methylene-tetrahydrofolate dehydrogenase [Sinorhizobium medicae].	46.74	291	147	4	5	291	4	290	3e-70	231
rs:WP_027033515	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium loti].	45.42	295	145	5	3	289	2	288	3e-70	231
sp:FOLD1_RHIEC	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.58	294	152	4	3	292	2	291	3e-70	231
rs:WP_028717497	methenyltetrahydrofolate cyclohydrolase [Paracoccus sp. J39].	45.14	288	151	2	5	292	9	289	3e-70	231
rs:WP_028930471	5,10-methylene-tetrahydrofolate cyclohydrolase [Pseudonocardia asaccharolytica].	45.33	289	143	4	1	289	1	274	3e-70	231
tr:A0A0A8L708_9SACH	SubName: Full=WGS project CCBQ000000000 data, contig 00046 {ECO:0000313|EMBL:CDO94816.1};	45.27	296	150	5	5	293	3	293	3e-70	244
rs:XP_001684039	putative C-1-tetrahydrofolate synthase,cytoplasmic [Leishmania major strain Friedlin].	44.11	297	157	4	2	293	3	295	3e-70	231
rs:WP_028439167	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	41.78	292	160	5	1	292	1	282	3e-70	231
rs:WP_008552752	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudovibrio sp. JE062].	45.24	294	151	5	3	291	4	292	3e-70	231
rs:WP_037932951	methenyltetrahydrofolate cyclohydrolase [Streptomyces toyocaensis].	40.96	293	163	4	1	293	1	283	3e-70	231
rs:WP_025080293	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus hamsteri].	45.36	291	145	5	3	292	2	279	3e-70	231
tr:M7BBL9_CHEMY	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:EMP32960.1};	48.31	267	103	3	30	294	4	237	3e-70	229
rs:WP_004984258	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	40.61	293	164	4	1	293	1	283	3e-70	231
tr:W1Q897_OGAPD	SubName: Full=C-1-tetrahydrofolate synthase, mitochondrial {ECO:0000313|EMBL:ESW96196.1}; EC=1.5.1.5 {ECO:0000313|EMBL:ESW96196.1};	41.98	293	161	5	5	292	3	291	3e-70	231
tr:D7ANU4_THEM3	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.27	293	159	4	1	293	1	277	3e-70	230
rs:WP_014563375	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus helveticus].	45.20	281	142	3	3	283	2	270	3e-70	230
sp:FOLD_BARQU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.26	294	146	5	4	291	3	290	3e-70	231
rs:WP_026219905	methenyltetrahydrofolate cyclohydrolase [Streptomyces vitaminophilus].	42.12	292	159	4	1	292	1	282	3e-70	231
rs:WP_022006943	bifunctional protein FolD [Proteobacteria bacterium CAG:495].	44.71	293	146	4	1	292	1	278	3e-70	231
rs:WP_006722021	methenyltetrahydrofolate cyclohydrolase [Collinsella stercoris].	49.03	257	119	4	36	290	34	280	3e-70	231
rs:WP_015343851	bifunctional protein FolD [Rhizobium tropici].	44.90	294	154	4	3	292	4	293	3e-70	231
rs:WP_037989013	5,10-methylene-tetrahydrofolate cyclohydrolase [Synechococcus sp. BL107].	45.23	283	145	3	6	288	5	277	3e-70	231
rs:WP_030413985	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	42.12	292	159	5	1	292	1	282	3e-70	231
rs:WP_018089548	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. FxanaC1].	42.12	292	159	5	1	292	1	282	3e-70	231
tr:A0A067FA90_CITSI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDO64228.1};	46.39	263	135	2	32	292	7	265	3e-70	230
rs:WP_037037741	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. BAY1663].	47.59	290	142	5	4	292	8	288	3e-70	231
rs:WP_045229784	methenyltetrahydrofolate cyclohydrolase [Agrobacterium rubi].	45.08	295	154	4	3	293	2	292	3e-70	231
rs:WP_006133515	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	40.96	293	163	4	1	293	1	283	3e-70	230
rs:WP_006925621	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella washoensis].	44.90	294	150	5	4	291	3	290	3e-70	231
tr:Q065C6_9SYNE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.23	283	145	3	6	288	14	286	3e-70	231
rs:XP_011144575	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Harpegnathos saltator].	46.76	293	148	3	3	289	31	321	3e-70	232
rs:WP_016487090	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas putida].	44.71	293	154	4	2	294	3	287	3e-70	231
tr:W5FTU6_WHEAT	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Traes_5DL_5DF1A8809.1};	43.15	292	160	2	2	291	88	375	3e-70	233
rs:XP_006694970	C-1-tetrahydrofolate synthase-like protein [Chaetomium thermophilum var. thermophilum DSM 1495].	44.83	290	153	3	6	292	140	425	3e-70	245
tr:A0A0D6PL42_9PROT	SubName: Full=Bifunctional [5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase] {ECO:0000313|EMBL:GAN81484.1};	44.98	289	150	3	3	291	9	288	3e-70	231
rs:WP_030030342	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	42.47	292	158	5	1	292	1	282	4e-70	230
rs:XP_006660541	PREDICTED: bifunctional protein FolD 1, mitochondrial-like [Oryza brachyantha].	44.33	291	156	2	2	290	88	374	4e-70	234
rs:WP_005855238	5,10-methylene-tetrahydrofolate dehydrogenase [Sagittula stellata].	45.73	293	154	2	1	292	1	289	4e-70	231
rs:WP_006922968	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella washoensis].	44.90	294	150	5	4	291	3	290	4e-70	231
rs:WP_026007812	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fuscovaginae].	47.00	283	142	3	6	288	11	285	4e-70	231
rs:WP_042085245	methenyltetrahydrofolate cyclohydrolase [alpha proteobacterium Q-1].	44.67	291	156	2	3	292	9	295	4e-70	231
rs:WP_031128713	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL WC-3719].	41.44	292	161	5	1	292	1	282	4e-70	230
rs:WP_027486805	methenyltetrahydrofolate cyclohydrolase [Rhizobium undicola].	45.70	291	150	4	5	291	4	290	4e-70	231
rs:WP_019088833	5,10-methylene-tetrahydrofolate dehydrogenase [Acetobacter pasteurianus].	45.67	289	151	2	2	290	14	296	4e-70	231
rs:WP_003627597	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus helveticus].	44.84	281	143	3	3	283	2	270	4e-70	230
rs:WP_020777454	tetrahydrofolate dehydrogenase [Leptospira meyeri].	40.14	294	162	3	2	295	3	282	4e-70	231
rs:WP_017239671	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. SS].	42.31	286	155	4	1	286	1	276	4e-70	230
rs:XP_005078377	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Mesocricetus auratus].	46.39	263	134	3	3	259	37	298	4e-70	231
rs:WP_018208055	5,10-methylene-tetrahydrofolate dehydrogenase [Sinorhizobium medicae].	46.67	285	143	4	5	288	11	287	4e-70	231
gp:CP003784_269	methylenetetrahydrofolate dehydrogenase [Bartonella quintana RM-11]	46.60	294	145	5	4	291	21	308	4e-70	231
rs:WP_039719666	methenyltetrahydrofolate cyclohydrolase [Candidatus Riesia pediculischaeffi].	43.79	290	153	2	1	290	1	280	4e-70	230
rs:WP_012650951	5,10-methylene-tetrahydrofolate dehydrogenase [Agrobacterium tumefaciens].	44.86	292	153	4	5	292	4	291	4e-70	231
rs:WP_034520298	methenyltetrahydrofolate cyclohydrolase [Agrobacterium rhizogenes].	45.21	292	152	4	5	292	4	291	4e-70	231
rs:WP_036917961	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus].	43.21	287	156	2	3	286	2	284	4e-70	231
rs:WP_025164549	methenyltetrahydrofolate cyclohydrolase [Pseudomonas taeanensis].	45.67	289	149	3	2	290	6	286	4e-70	231
rs:WP_034769497	methenyltetrahydrofolate cyclohydrolase [Hyphomonas sp. CY54-11-8].	47.60	292	141	5	1	289	1	283	4e-70	231
rs:WP_046779185	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. fd2-tb].	42.47	292	158	5	1	292	1	282	4e-70	230
rs:WP_041723709	methenyltetrahydrofolate cyclohydrolase [Agrobacterium tumefaciens].	44.75	295	155	4	2	292	3	293	4e-70	231
tr:B9JJ42_AGRRK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.75	295	155	4	2	292	6	296	4e-70	231
rs:WP_008693223	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium nucleatum].	44.25	287	148	4	5	290	2	277	4e-70	230
rs:XP_011271812	C-1-tetrahydrofolate synthase, mitochondrial [Wickerhamomyces ciferrii].	45.36	291	152	3	6	293	24	310	4e-70	244
rs:WP_010566654	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas extremaustralis].	45.86	290	148	4	1	289	1	282	5e-70	231
rs:WP_004939178	FolD 1 [Acinetobacter soli].	47.77	291	141	6	2	290	10	291	5e-70	231
rs:XP_010185153	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Mesitornis unicolor].	51.46	239	109	3	63	295	1	238	5e-70	229
sp:FOLD_LEPBA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.82	294	160	3	2	295	3	282	5e-70	230
gp:CP000097_731	Methenyltetrahydrofolate cyclohydrolase [Synechococcus sp. CC9902]	45.23	283	145	3	6	288	14	286	5e-70	231
rs:XP_003589595	Bifunctional protein folD [Medicago truncatula].	45.05	293	153	4	2	291	17	304	5e-70	231
rs:WP_013014620	5,10-methylene-tetrahydrofolate dehydrogenase [Meiothermus ruber].	44.95	287	146	5	6	291	4	279	5e-70	230
rs:WP_007125349	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus ultunensis].	44.13	281	145	3	3	283	2	270	5e-70	230
rs:WP_033181604	bifunctional protein FolD [Rhizobium leguminosarum].	45.89	292	150	4	5	292	4	291	5e-70	231
rs:WP_018720568	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora pacifica].	42.12	292	163	4	1	292	1	286	5e-70	230
sp:FOLD_SYNPW	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.29	283	142	3	6	288	5	277	5e-70	230
rs:WP_025014841	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus kitasatonis].	43.77	281	146	3	3	283	2	270	5e-70	230
rs:WP_018222691	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora pacifica].	42.47	292	162	4	1	292	1	286	5e-70	230
sp:FOLD_SYNS9	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.23	283	145	3	6	288	5	277	5e-70	230
rs:WP_008798627	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium nucleatum].	44.25	287	148	4	5	290	2	277	5e-70	230
rs:WP_045650046	methenyltetrahydrofolate cyclohydrolase [Hoeflea sp. BRH_c9].	46.10	295	149	5	3	292	2	291	5e-70	231
rs:WP_005910670	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium].	44.25	287	148	4	5	290	2	277	5e-70	230
rs:WP_031996117	methenyltetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	46.53	288	143	5	5	290	13	291	5e-70	231
rs:WP_033271682	methenyltetrahydrofolate cyclohydrolase [Streptomyces lydicus].	42.12	292	159	5	1	292	1	282	5e-70	230
rs:WP_043624969	methenyltetrahydrofolate cyclohydrolase [Ensifer sp. ZNC0028].	46.74	291	147	4	5	291	4	290	5e-70	231
rs:WP_044018656	5,10-methylene-tetrahydrofolate cyclohydrolase [Thermoanaerobacter italicus].	40.14	289	157	4	5	293	2	274	5e-70	230
rs:WP_037446389	methenyltetrahydrofolate cyclohydrolase, partial [Skermanella stibiiresistens].	44.70	302	151	6	2	292	3	299	5e-70	231
rs:WP_028029064	methenyltetrahydrofolate cyclohydrolase [Gemmobacter nectariphilus].	45.70	291	151	3	1	291	1	284	5e-70	230
rs:WP_029071375	methenyltetrahydrofolate cyclohydrolase [Kandleria vitulina].	44.76	286	148	3	5	290	2	277	5e-70	230
rs:WP_014273488	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia slovaca].	41.02	295	163	3	4	297	3	287	5e-70	230
rs:WP_042147487	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NBRC 110027].	42.12	292	159	5	1	292	1	282	5e-70	230
rs:WP_031589504	methenyltetrahydrofolate cyclohydrolase [Kandleria vitulina].	45.45	286	146	3	5	290	2	277	5e-70	230
rs:WP_037110965	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. MGL06].	45.58	294	152	4	3	292	2	291	5e-70	230
rs:XP_003383119	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Amphimedon queenslandica].	42.24	303	163	4	1	294	38	337	6e-70	232
rs:WP_034565370	5,10-methylene-tetrahydrofolate cyclohydrolase [Carnobacterium gallinarum].	44.44	288	149	4	6	293	1	277	6e-70	229
rs:WP_036704899	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Paracoccus].	45.70	291	147	2	1	291	1	280	6e-70	230
sp:FOLD_BARHE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.24	294	149	5	4	291	3	290	6e-70	230
rs:XP_503399	YALI0E01056p [Yarrowia lipolytica].	44.71	293	155	3	3	292	2	290	6e-70	244
rs:WP_043265722	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. CT34].	41.78	292	160	5	1	292	1	282	6e-70	230
rs:WP_018072596	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium leguminosarum].	45.89	292	150	4	5	292	4	291	6e-70	230
rs:WP_023586931	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces thermolilacinus].	41.44	292	161	5	1	292	1	282	6e-70	230
rs:WP_038525739	methenyltetrahydrofolate cyclohydrolase [Azospirillum brasilense].	46.34	287	146	4	3	286	4	285	6e-70	230
tr:A0A094S8I3_9ZZZZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGA14248.1};	41.92	291	158	5	1	291	1	280	6e-70	230
rs:WP_034547898	5,10-methylene-tetrahydrofolate cyclohydrolase [Carnobacterium alterfunditum].	43.99	291	152	3	1	291	1	280	6e-70	230
rs:WP_026392048	hypothetical protein [Acholeplasma modicum].	47.37	247	119	2	38	284	31	266	6e-70	229
tr:L1L8S3_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.44	292	161	4	1	292	1	282	6e-70	230
rs:WP_028719657	methenyltetrahydrofolate cyclohydrolase [Paracoccus yeei].	45.52	290	150	3	3	292	2	283	6e-70	230
rs:WP_030928484	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-646].	41.44	292	161	4	1	292	1	282	6e-70	230
sp:FOLD_RICFE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.72	290	158	3	4	292	3	282	6e-70	230
gp:CP000053_699	Methylenetetrahydrofolate dehydrogenase [Rickettsia felis URRWXCal2]	41.72	290	158	3	4	292	9	288	6e-70	230
tr:B9JIB8_AGRRK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.08	295	154	4	2	292	6	296	6e-70	230
rs:WP_013544589	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella clarridgeiae].	45.08	295	150	5	4	292	3	291	6e-70	230
rs:WP_008559906	5,10-methylene-tetrahydrofolate dehydrogenase [Ruegeria sp. R11].	45.21	292	153	3	1	292	1	285	6e-70	230
rs:XP_001226602	conserved hypothetical protein [Chaetomium globosum CBS 148.51].	44.93	296	156	3	1	293	1	292	7e-70	244
rs:WP_018726138	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora pacifica].	42.12	292	163	4	1	292	1	286	7e-70	230
rs:WP_004561597	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus hilgardii].	42.86	294	156	4	3	294	2	285	7e-70	230
sp:FOLD_RICPR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.71	295	156	4	1	293	1	284	7e-70	230
rs:WP_015423035	5,10-methylene-tetrahydrofolate dehydrogenase [uncultured Termite group 1 bacterium].	44.03	293	145	4	4	288	2	283	7e-70	230
rs:WP_008821357	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium periodonticum].	44.25	287	148	4	5	290	2	277	7e-70	229
rs:WP_028991929	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Thermoanaerobacter].	40.48	289	156	4	5	293	2	274	7e-70	229
rs:WP_046783211	methenyltetrahydrofolate cyclohydrolase [Lactobacillus plantarum].	46.39	291	143	5	4	292	3	282	7e-70	230
rs:WP_031053189	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	41.30	293	162	4	1	293	1	283	7e-70	229
rs:WP_018468437	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. LaPpAH-202].	42.31	286	155	5	1	286	1	276	7e-70	230
rs:WP_007633251	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium sp. CCGE 510].	45.58	294	152	4	3	292	2	291	7e-70	230
rs:WP_041723700	methenyltetrahydrofolate cyclohydrolase [Agrobacterium tumefaciens].	45.08	295	154	4	2	292	3	293	7e-70	230
gp:CP006899_368	hypothetical protein [Brucella ceti TE28753-12]	49.61	258	122	4	39	292	1	254	7e-70	229
rs:WP_022007635	bifunctional protein FolD [Coprobacillus sp. CAG:183].	47.55	286	136	4	5	288	2	275	7e-70	229
rs:WP_028064198	hypothetical protein [Solirubrobacter soli].	42.71	288	154	2	5	292	3	279	7e-70	229
rs:WP_015508410	carbonic anhydrase [Rickettsia prowazekii].	42.71	295	156	4	1	293	25	308	7e-70	231
rs:WP_046603529	methenyltetrahydrofolate cyclohydrolase [Neorhizobium galegae].	45.58	294	152	4	3	292	2	291	7e-70	230
rs:WP_046845380	methenyltetrahydrofolate cyclohydrolase [Hyphomicrobium sp. GJ21].	46.10	282	146	2	3	284	4	279	7e-70	230
rs:WP_032525705	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus marinus].	43.01	286	158	2	6	291	5	285	7e-70	230
tr:K7KE38_SOYBN	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:GLYMA03G241.3};	43.77	281	152	2	15	293	3	279	7e-70	229
rs:WP_029073047	methenyltetrahydrofolate cyclohydrolase [Kandleria vitulina].	45.10	286	147	3	5	290	2	277	7e-70	229
rs:WP_003948498	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	42.31	286	155	5	1	286	1	276	7e-70	229
tr:S9X9X1_SCHCR	SubName: Full=6,7,8-tetrahydrofolate synthase {ECO:0000313|EMBL:EPY50566.1};	45.17	290	152	3	3	289	2	287	7e-70	243
tr:W9H8G7_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.30	298	147	6	2	288	3	295	7e-70	231
rs:WP_007826200	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. Tu6071].	40.96	293	163	5	1	293	1	283	7e-70	229
rs:WP_046508752	methenyltetrahydrofolate cyclohydrolase [Kiloniella sp. P1-1].	45.08	295	151	4	2	292	3	290	8e-70	230
rs:WP_037457235	methenyltetrahydrofolate cyclohydrolase [Sphingobium chlorophenolicum].	47.22	288	145	3	3	290	2	282	8e-70	230
tr:S9VRB0_SCHCR	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:EPY50483.1};	47.28	294	145	4	2	292	36	322	8e-70	244
rs:WP_006611904	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobium sp. ORS 285].	46.37	289	149	2	1	289	1	283	8e-70	230
sp:FOLD_BART1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.86	292	153	4	4	291	3	290	8e-70	230
tr:B9FHE0_ORYSJ	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EEE62355.1};	46.21	264	136	2	32	293	145	404	8e-70	233
tr:B9FHE0_ORYSJ	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EEE62355.1};	44.06	143	78	1	3	143	2	144	9e-27	118
sp:FOLD_LACPL	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.39	291	143	5	4	292	3	282	8e-70	229
tr:A0A067TEP0_9AGAR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDR81616.1};	45.95	296	150	4	2	291	11	302	8e-70	243
rs:WP_018817082	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora pacifica].	42.12	292	163	4	1	292	1	286	8e-70	229
rs:WP_042786260	methenyltetrahydrofolate cyclohydrolase [Acetobacter aceti].	45.67	289	151	2	2	290	14	296	8e-70	230
rs:WP_027957679	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Halomonas].	44.90	294	152	3	2	290	8	296	8e-70	230
rs:WP_028751235	methenyltetrahydrofolate cyclohydrolase [Rhizobium leucaenae].	45.89	292	150	4	5	292	4	291	8e-70	230
rs:WP_025899942	methenyltetrahydrofolate cyclohydrolase [Sneathiella glossodoripedis].	43.84	292	158	2	1	292	1	286	8e-70	230
rs:WP_007700140	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium sp. AP16].	44.52	292	154	4	5	292	4	291	8e-70	230
rs:WP_025616697	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	42.12	292	163	4	1	292	1	286	8e-70	229
tr:A0A0D2FR45_9EURO	SubName: Full=Unplaced genomic scaffold supercont1.18, whole genome shotgun sequence {ECO:0000313|EMBL:KIW89037.1};	45.55	292	152	3	1	289	1	288	8e-70	243
rs:WP_046035765	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	47.37	285	142	3	6	290	31	307	8e-70	231
tr:A0A081CDB8_CANAR	SubName: Full=FTHFS-domain-containing protein {ECO:0000313|EMBL:GAK64664.1};	45.64	298	151	5	3	293	84	377	9e-70	244
tr:A0A0D8IWG8_9FIRM	SubName: Full=5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:KJF39055.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KJF39055.1}; EC=3.5.4.9 {ECO:0000313|EMBL:KJF39055.1};	49.41	255	119	2	36	290	34	278	9e-70	229
rs:WP_014586756	5,10-methylene-tetrahydrofolate dehydrogenase [Methanosaeta harundinacea].	43.36	286	150	3	5	290	13	286	9e-70	230
rs:WP_004704295	MULTISPECIES: FolD 1 [Acinetobacter].	46.53	288	143	5	5	290	13	291	9e-70	230
rs:WP_003640349	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus plantarum].	46.39	291	143	5	4	292	6	285	9e-70	229
rs:WP_022078734	bifunctional protein FolD [Acetobacter sp. CAG:267].	42.23	296	155	4	1	295	1	281	9e-70	229
tr:A0A0D9XCJ1_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:LPERR09G04040.1};	44.79	288	153	2	5	290	89	372	9e-70	233
rs:WP_031149615	methenyltetrahydrofolate cyclohydrolase [Streptomyces erythrochromogenes].	42.47	292	158	5	1	292	1	282	9e-70	229
rs:WP_006985961	5,10-methylene-tetrahydrofolate dehydrogenase [Cardiobacterium valvarum].	44.83	290	153	2	1	290	1	283	9e-70	229
rs:XP_004199295	Piso0_002728 [Millerozyma farinosa CBS 7064].	45.08	295	153	4	1	290	1	291	9e-70	243
rs:WP_004926834	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces griseoflavus].	40.61	293	164	4	1	293	1	283	9e-70	229
rs:WP_028738223	methenyltetrahydrofolate cyclohydrolase [Rhizobium selenitireducens].	43.15	292	158	4	4	291	3	290	9e-70	230
tr:J8RSM1_PSEPU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.91	281	142	4	4	283	8	279	9e-70	231
rs:WP_030211332	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	43.01	286	153	4	1	286	1	276	9e-70	229
rs:WP_008382467	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodovulum sp. PH10].	45.42	284	149	2	3	286	7	284	9e-70	230
rs:WP_014918575	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus helveticus].	44.84	281	143	3	3	283	2	270	1e-69	229
rs:WP_040276204	methenyltetrahydrofolate cyclohydrolase [Streptomonospora alba].	42.32	293	158	5	1	293	1	282	1e-69	229
rs:WP_044179333	methenyltetrahydrofolate cyclohydrolase [Granulicella mallensis].	42.39	309	153	6	1	290	1	303	1e-69	230
rs:XP_003650869	hypothetical protein THITE_2110770 [Thielavia terrestris NRRL 8126].	44.26	296	158	3	1	293	1	292	1e-69	243
rs:WP_027279158	methenyltetrahydrofolate cyclohydrolase [Rhodopseudomonas palustris].	46.02	289	151	2	1	289	1	284	1e-69	229
tr:A0A0C3S1P0_PHLGI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIP09081.1};	45.12	297	153	4	2	292	3	295	1e-69	243
rs:WP_041931153	methenyltetrahydrofolate cyclohydrolase [Pseudomonas brassicacearum].	46.67	285	144	3	6	290	12	288	1e-69	230
rs:WP_030082875	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	41.78	292	160	5	1	292	1	282	1e-69	229
rs:WP_021238637	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium quisquiliarum].	47.55	286	145	2	4	289	5	285	1e-69	229
rs:WP_030562303	methenyltetrahydrofolate cyclohydrolase [Streptomyces aureocirculatus].	42.27	291	158	5	1	291	1	281	1e-69	229
rs:WP_037222207	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. YR060].	44.86	292	153	4	5	292	1	288	1e-69	229
rs:XP_010557911	PREDICTED: bifunctional protein FolD 2 [Tarenaya hassleriana].	44.71	293	156	2	3	293	9	297	1e-69	229
rs:WP_018486411	bifunctional protein FolD [Rhizobium leguminosarum].	45.89	292	150	4	5	292	4	291	1e-69	229
rs:WP_018011022	5,10-methylene-tetrahydrofolate dehydrogenase [Sinorhizobium medicae].	46.64	283	142	4	5	286	11	285	1e-69	229
tr:G8NTC8_GRAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.39	309	153	6	1	290	6	308	1e-69	230
tr:X0QSE9_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.27	291	157	3	2	292	7	286	1e-69	229
rs:WP_041093454	methenyltetrahydrofolate cyclohydrolase [Lactobacillus hokkaidonensis].	46.10	295	140	8	3	292	2	282	1e-69	229
rs:WP_018234792	5,10-methylene-tetrahydrofolate dehydrogenase [Ensifer sp. BR816].	47.26	292	144	5	5	291	4	290	1e-69	229
rs:WP_004597781	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia prowazekii].	42.71	295	156	4	1	293	25	308	1e-69	230
tr:A0A0D6NH54_9PROT	SubName: Full=Bifunctional [5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase] {ECO:0000313|EMBL:GAN64970.1};	44.64	289	154	2	2	290	12	294	1e-69	230
rs:WP_013217165	5,10-methylene-tetrahydrofolate dehydrogenase [Hyphomicrobium denitrificans].	45.74	282	147	2	3	284	4	279	1e-69	229
rs:WP_034415533	methenyltetrahydrofolate cyclohydrolase, partial [Deinococcus marmoris].	49.03	257	124	3	34	290	30	279	1e-69	229
rs:WP_014284069	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudovibrio sp. FO-BEG1].	44.90	294	152	5	3	291	4	292	1e-69	230
rs:WP_028236568	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	46.67	285	144	3	6	290	12	288	1e-69	230
tr:A0A094Q350_9ZZZZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGA18545.1};	44.72	284	146	5	1	284	1	273	1e-69	229
rs:WP_020920404	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium etli].	45.55	292	151	4	5	292	4	291	1e-69	229
rs:XP_008822997	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Nannospalax galili].	44.41	295	116	4	3	291	37	289	1e-69	230
sp:C1TC_SCHPO	RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3;	43.34	293	153	4	3	289	2	287	1e-69	243
tr:A0A0D6N2A2_9PROT	SubName: Full=Bifunctional [5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase] {ECO:0000313|EMBL:GAN59698.1};	44.29	289	155	2	2	290	12	294	1e-69	229
rs:WP_022692578	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonas-like bacterium B12].	45.94	283	144	4	3	285	2	275	1e-69	229
rs:XP_005779339	hypothetical protein EMIHUDRAFT_315091 [Emiliania huxleyi CCMP1516].	42.18	294	160	3	2	292	27	313	1e-69	230
rs:WP_027912399	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Pseudomonas].	46.67	285	144	3	6	290	12	288	1e-69	229
rs:WP_026155261	methenyltetrahydrofolate cyclohydrolase [Paracoccus sp. N5].	43.84	292	156	3	1	292	1	284	1e-69	229
rs:WP_007384188	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sviceus].	40.96	293	163	4	1	293	1	283	1e-69	229
rs:WP_030851372	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-4474].	42.47	292	158	5	1	292	1	282	1e-69	229
rs:WP_020118645	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces canus].	41.30	293	162	4	1	293	1	283	1e-69	229
tr:A0A0D2ACE6_9EURO	SubName: Full=Strain CBS 40295 unplaced genomic scaffold supercont1.1, whole genome shotgun sequence {ECO:0000313|EMBL:KIV96618.1};	44.18	292	156	3	1	289	130	417	1e-69	243
rs:WP_039391060	methenyltetrahydrofolate cyclohydrolase [Novosphingobium sp. MBES04].	46.39	291	148	4	3	293	2	284	1e-69	229
sp:FOLD2_ROSDO	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.37	293	158	2	1	292	1	289	1e-69	229
rs:WP_018688688	5,10-methylene-tetrahydrofolate dehydrogenase [Ahrensia kielensis].	45.92	294	151	4	3	292	2	291	1e-69	229
tr:A0A0E0HK74_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA06G01780.1};	44.67	291	155	2	2	290	95	381	1e-69	232
rs:WP_035616653	methenyltetrahydrofolate cyclohydrolase [Hyphomonas johnsonii].	47.26	292	142	5	1	289	1	283	1e-69	229
rs:XP_007131273	PREDICTED: LOW QUALITY PROTEIN: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Physeter catodon].	45.79	297	143	5	3	291	37	323	1e-69	231
tr:M9MGC9_PSEA3	SubName: Full=C1-tetrahydrofolate synthase {ECO:0000313|EMBL:GAC75087.1};	45.30	298	152	5	3	293	84	377	1e-69	243
rs:WP_026355963	methenyltetrahydrofolate cyclohydrolase [Pannonibacter phragmitetus].	43.94	289	155	2	3	291	11	292	1e-69	229
rs:WP_031486565	methenyltetrahydrofolate cyclohydrolase [Streptomyces bicolor].	41.78	292	160	4	1	292	1	282	1e-69	229
rs:WP_008795074	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium nucleatum].	44.25	287	148	4	5	290	2	277	1e-69	229
rs:WP_029229323	hypothetical protein [Calescamantes bacterium JGI 0000106-I17].	40.47	299	160	4	1	284	1	296	2e-69	230
rs:WP_025005854	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus gallinarum].	45.00	280	142	3	4	283	3	270	2e-69	229
rs:WP_018729221	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora pacifica].	42.12	292	163	4	1	292	1	286	2e-69	229
rs:XP_002171404	C-1-tetrahydrofolate synthase [Schizosaccharomyces japonicus yFS275].	46.08	293	148	4	1	290	34	319	2e-69	243
rs:WP_034800773	methenyltetrahydrofolate cyclohydrolase [Ensifer adhaerens].	46.74	291	147	4	5	291	4	290	2e-69	229
rs:WP_033608627	bifunctional protein FolD [Lactobacillus plantarum].	46.05	291	144	5	4	292	3	282	2e-69	229
rs:XP_002460058	hypothetical protein SORBIDRAFT_02g022160 [Sorghum bicolor].	43.84	292	158	2	2	291	93	380	2e-69	232
rs:WP_030659440	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	42.47	292	158	5	1	292	1	282	2e-69	229
tr:A0A085VKP1_PSESX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.61	285	147	3	6	290	11	287	2e-69	229
sp:FOLD_MACCJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.49	292	153	4	1	292	1	280	2e-69	229
rs:WP_035405590	5,10-methylene-tetrahydrofolate dehydrogenase [Chlamydia suis].	41.49	282	159	3	5	285	2	278	2e-69	229
rs:WP_026018587	methenyltetrahydrofolate cyclohydrolase [Komagataeibacter europaeus].	45.67	289	151	2	2	290	14	296	2e-69	229
rs:WP_032519095	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus marinus].	42.71	288	160	2	6	293	5	287	2e-69	229
rs:WP_038820411	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas aeruginosa].	48.13	241	121	1	1	241	1	237	2e-69	227
tr:A4GJ70_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.81	292	151	6	1	291	1	277	2e-69	228
rs:WP_024716665	methenyltetrahydrofolate cyclohydrolase [Gluconobacter oxydans].	45.17	290	153	2	3	292	11	294	2e-69	229
rs:WP_007688566	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Sphingomonadaceae].	47.39	287	146	2	3	289	4	285	2e-69	229
tr:X1U2F5_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_S10229 {ECO:0000313|EMBL:GAI93985.1}; Flags: Fragment;	53.05	213	90	3	78	290	1	203	2e-69	226
rs:WP_015680655	tetrahydrofolate dehydrogenase [Leptospira wolbachii].	40.48	294	161	3	2	295	3	282	2e-69	229
rs:WP_007534543	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium mesoamericanum].	44.41	295	156	4	2	292	3	293	2e-69	229
rs:WP_012756088	bifunctional protein FolD [Rhizobium leguminosarum].	45.55	292	151	4	5	292	4	291	2e-69	229
rs:WP_042474230	methenyltetrahydrofolate cyclohydrolase [Agrobacterium rhizogenes].	44.52	292	154	4	5	292	4	291	2e-69	229
rs:WP_030040919	methenyltetrahydrofolate cyclohydrolase [Streptomyces resistomycificus].	41.44	292	161	4	1	292	1	282	2e-69	229
rs:WP_020751582	methylenetetrahydrofolate dehydrogenase [Lactobacillus casei].	45.10	286	146	3	6	291	5	279	2e-69	228
rs:WP_017992953	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium leguminosarum].	45.55	292	151	4	5	292	4	291	2e-69	229
rs:WP_025861542	methenyltetrahydrofolate cyclohydrolase [Acetobacter papayae].	45.21	292	154	2	2	293	13	298	2e-69	229
rs:WP_035858281	methenyltetrahydrofolate cyclohydrolase [Cryptosporangium arvum].	42.27	291	157	5	1	291	1	280	2e-69	228
sp:FOLD_GLUOX	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.17	290	153	2	3	292	13	296	2e-69	229
rs:WP_009066091	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	41.10	292	162	5	1	292	1	282	2e-69	228
rs:WP_042918224	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas aeruginosa].	48.13	241	121	1	1	241	1	237	2e-69	227
rs:WP_002879680	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus delbrueckii].	43.10	290	153	4	3	292	2	279	2e-69	228
rs:XP_003692231	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2-like [Apis florea].	44.78	297	155	4	2	292	57	350	2e-69	231
rs:WP_007266004	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. C].	42.47	292	158	5	1	292	1	282	2e-69	229
sp:FOLD_SYNPX	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.64	283	141	3	6	288	5	277	2e-69	229
rs:WP_017967061	bifunctional protein FolD [Rhizobium leguminosarum].	45.55	292	151	4	5	292	4	291	2e-69	229
rs:WP_004864464	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella vinsonii].	45.42	295	149	5	4	292	3	291	2e-69	229
tr:T0L7J7_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.60	250	130	1	41	290	1	249	2e-69	228
rs:WP_008003706	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. GM49].	46.32	285	145	3	6	290	15	291	2e-69	229
rs:WP_026549971	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. Br18].	42.76	297	157	6	2	292	5	294	2e-69	229
rs:XP_009538757	hypothetical protein PHYSODRAFT_307593 [Phytophthora sojae].	42.44	311	153	6	5	293	13	319	2e-69	229
sp:FOLD_METHJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.91	281	137	3	5	285	2	267	2e-69	228
rs:WP_034001142	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas aeruginosa].	48.13	241	121	1	1	241	1	237	2e-69	227
tr:G7I8G5_MEDTR	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:AES59846.2}; SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AFK44079.1, ECO:0000313|EnsemblPlants:AES59846};	45.05	293	153	4	2	291	69	356	2e-69	231
rs:WP_006970075	5,10-methylene-tetrahydrofolate dehydrogenase [Plesiocystis pacifica].	43.45	290	159	2	2	291	5	289	2e-69	229
rs:WP_018541647	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. MspMP-M5].	42.12	292	159	5	1	292	1	282	2e-69	228
sp:FOLD_RHOCS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.19	301	158	3	3	297	4	300	2e-69	229
rs:WP_039155116	methenyltetrahydrofolate cyclohydrolase, partial [Leisingera sp. ANG-S].	47.16	282	142	3	1	282	1	275	2e-69	228
tr:F9EKG9_FUSNU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.90	287	149	4	5	290	2	277	2e-69	228
tr:K2RQ38_MACPH	SubName: Full=Formate-tetrahydrofolate ligase FTHFS {ECO:0000313|EMBL:EKG12334.1};	44.52	292	155	3	1	289	1	288	2e-69	242
rs:WP_033210563	methenyltetrahydrofolate cyclohydrolase [Streptomyces wedmorensis].	41.96	286	156	4	1	286	1	276	2e-69	228
tr:T0VAC6_9STRE	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+)/ Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EQC78409.1}; EC=1.5.1.5 {ECO:0000313|EMBL:EQC78409.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EQC78409.1};	48.10	289	140	3	5	293	4	282	2e-69	236
rs:WP_035049462	methenyltetrahydrofolate cyclohydrolase [Caulobacter henricii].	45.05	293	153	2	3	291	4	292	2e-69	229
rs:WP_046912477	methenyltetrahydrofolate cyclohydrolase [Streptomyces showdoensis].	41.10	292	162	4	1	292	1	282	2e-69	228
rs:WP_028824641	methenyltetrahydrofolate cyclohydrolase [Proteobacteria bacterium JGI 0000113-P07].	44.29	289	156	2	1	288	1	285	2e-69	229
rs:WP_045683795	methenyltetrahydrofolate cyclohydrolase [Roseovarius sp. BRH_c41].	45.58	294	149	3	1	292	1	285	2e-69	229
rs:WP_027063603	methenyltetrahydrofolate cyclohydrolase [Mesoplasma seiffertii].	43.46	283	151	2	4	286	2	275	2e-69	228
rs:WP_045644467	methenyltetrahydrofolate cyclohydrolase [Peptococcaceae bacterium BRH_c4b].	42.01	288	156	3	3	290	2	278	2e-69	228
rs:WP_018699059	hypothetical protein [Amorphus coralli].	45.39	293	154	3	1	291	1	289	2e-69	229
rs:WP_016385991	bifunctional protein FolD [Lactobacillus paracasei].	45.10	286	146	3	6	291	5	279	2e-69	228
rs:WP_018085088	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfurispora thermophila].	42.41	290	155	4	1	290	1	278	2e-69	228
rs:WP_024315635	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Rhizobium].	44.67	291	153	4	6	292	5	291	2e-69	229
rs:WP_040252911	methenyltetrahydrofolate cyclohydrolase [Streptomyces albus].	41.78	292	160	5	1	292	1	282	2e-69	228
rs:WP_006603724	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces auratus].	41.78	292	160	5	1	292	1	282	2e-69	228
rs:XP_010324896	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X2 [Solanum lycopersicum].	42.52	301	164	3	2	293	65	365	2e-69	231
rs:WP_024759217	methenyltetrahydrofolate cyclohydrolase [Streptomyces exfoliatus].	42.31	286	155	4	1	286	1	276	2e-69	228
sp:FOLD_PROMS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.21	289	160	3	6	293	5	287	3e-69	229
rs:WP_010704815	methylenetetrahydrofolate dehydrogenase [Bartonella vinsonii].	45.42	295	149	5	4	292	3	291	3e-69	229
tr:I4KKX0_PSEFL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.67	285	144	3	6	290	32	308	3e-69	229
rs:WP_003564670	MULTISPECIES: bifunctional protein FolD [Lactobacillus casei group].	45.10	286	146	3	6	291	5	279	3e-69	228
tr:A0A0D6XBK6_THEFI	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:KIX84716.1};	44.64	289	144	4	1	289	1	273	3e-69	228
tr:A0A0D2EIK6_9EURO	SubName: Full=Strain CBS 118157 unplaced genomic scaffold supercont1.4, whole genome shotgun sequence {ECO:0000313|EMBL:KIW54435.1};	43.49	292	158	3	1	289	75	362	3e-69	242
rs:XP_008223146	PREDICTED: bifunctional protein FolD 2-like [Prunus mume].	42.96	284	154	3	15	294	3	282	3e-69	228
rs:XP_003857701	trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase ADE3 [Zymoseptoria tritici IPO323].	43.84	292	157	3	1	289	1	288	3e-69	242
rs:WP_007001578	hypothetical protein [Actinobaculum massiliense].	40.20	296	168	6	1	292	1	291	3e-69	228
rs:WP_028748552	methenyltetrahydrofolate cyclohydrolase [Rhizobium mesoamericanum].	43.92	296	158	4	1	292	2	293	3e-69	229
rs:WP_004865254	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella vinsonii].	45.42	295	149	5	4	292	3	291	3e-69	229
rs:WP_036328336	methenyltetrahydrofolate cyclohydrolase [Microbispora sp. ATCC PTA-5024].	43.00	293	152	6	1	291	1	280	3e-69	228
rs:WP_008794128	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium periodonticum].	44.25	287	148	4	5	290	2	277	3e-69	228
tr:A0A090C4Z5_KLUMA	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:BAP72824.1};	44.75	295	153	4	5	293	3	293	3e-69	242
rs:WP_041112653	methenyltetrahydrofolate cyclohydrolase [Gluconobacter oxydans].	45.17	290	153	2	3	292	11	294	3e-69	229
rs:WP_025914726	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB245a_520K10].	42.01	288	162	2	6	293	5	287	3e-69	229
tr:F2KFA4_PSEBN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.67	285	144	3	6	290	32	308	3e-69	229
rs:WP_027048191	methenyltetrahydrofolate cyclohydrolase [Mesoplasma syrphidae].	43.79	290	154	2	4	293	2	282	3e-69	228
tr:A0A067Z1H4_GLUOY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.17	290	153	2	3	292	13	296	3e-69	229
rs:WP_037481779	methenyltetrahydrofolate cyclohydrolase [Sphingomonas paucimobilis].	47.55	286	145	2	4	289	5	285	3e-69	228
rs:WP_003560669	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus buchneri].	42.52	294	157	4	3	294	2	285	3e-69	228
rs:WP_042618052	methenyltetrahydrofolate cyclohydrolase [Agrobacterium tumefaciens].	44.75	295	155	4	3	293	2	292	3e-69	229
rs:XP_003541358	PREDICTED: bifunctional protein FolD 1, mitochondrial-like [Glycine max].	42.18	294	163	3	2	293	63	351	3e-69	230
rs:WP_045561280	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. FxanaA7].	41.10	292	162	4	1	292	1	282	3e-69	228
tr:C4JC05_MAIZE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ACR38705.1, ECO:0000313|EnsemblPlants:GRMZM2G130790_P01};	43.84	292	158	2	2	291	94	381	3e-69	231
rs:WP_030806420	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-2799].	41.92	291	159	4	1	291	1	281	3e-69	228
rs:XP_003648073	hypothetical protein Ecym_7435 [Eremothecium cymbalariae DBVPG#7215].	45.03	302	147	4	1	293	27	318	3e-69	242
rs:WP_007004324	5,10-methylene-tetrahydrofolate dehydrogenase [Roseomonas cervicalis].	45.67	289	143	3	1	289	1	275	3e-69	228
rs:WP_004139978	5,10-methylene-tetrahydrofolate dehydrogenase [Cardiobacterium hominis].	46.55	290	148	3	1	290	1	283	3e-69	228
tr:S9W2X6_9TRYP	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:EPY33686.1};	41.41	297	166	3	1	293	1	293	3e-69	228
sp:FOLD1_PSEPK	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.88	294	158	3	1	293	1	288	3e-69	228
rs:XP_010324895	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X1 [Solanum lycopersicum].	42.52	301	164	3	2	293	66	366	3e-69	231
rs:WP_016912082	tetrahydrofolate dehydrogenase [Staphylococcus vitulinus].	42.76	290	155	3	1	290	1	279	3e-69	228
rs:WP_029868027	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. JGI 0001002-E20].	45.21	292	152	4	5	292	4	291	3e-69	228
rs:WP_020048498	bifunctional protein FolD [Rhizobium leguminosarum].	45.55	292	151	4	5	292	4	291	3e-69	228
rs:WP_035227675	methenyltetrahydrofolate cyclohydrolase [Agrobacterium tumefaciens].	44.75	295	155	4	3	293	2	292	3e-69	228
rs:WP_035178584	methenyltetrahydrofolate cyclohydrolase [Lactobacillus farraginis].	41.50	294	160	4	3	294	2	285	3e-69	228
rs:WP_027666411	methenyltetrahydrofolate cyclohydrolase [Rhizobium leguminosarum].	45.55	292	151	4	5	292	4	291	3e-69	228
sp:FOLD2_RHIEC	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.05	293	153	4	4	292	3	291	3e-69	228
rs:WP_026857093	methenyltetrahydrofolate cyclohydrolase [Geodermatophilaceae bacterium URHB0062].	44.01	284	148	4	1	284	1	273	3e-69	228
tr:A0A074S2K6_9HOMO	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:KEP53494.1};	45.27	296	150	5	3	290	92	383	3e-69	242
rs:WP_025968697	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB245a_519D13].	42.56	289	159	3	6	293	5	287	3e-69	228
rs:WP_009153662	5,10-methylene-tetrahydrofolate dehydrogenase [Saccharomonospora marina].	41.24	291	156	3	1	291	1	276	3e-69	228
rs:WP_041476004	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	46.67	285	144	3	6	290	12	288	3e-69	229
rs:WP_008259940	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Brevundimonas].	44.70	302	154	4	1	293	1	298	3e-69	229
rs:WP_045948788	methenyltetrahydrofolate cyclohydrolase [Streptomyces katrae].	43.15	292	156	5	1	292	1	282	3e-69	228
rs:WP_003515126	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Agrobacterium].	44.41	295	156	4	3	293	2	292	3e-69	228
rs:WP_005968681	5,10-methylene-tetrahydrofolate dehydrogenase [Fusobacterium periodonticum].	43.90	287	149	4	5	290	2	277	3e-69	228
rs:WP_021731668	MULTISPECIES: methylenetetrahydrofolate dehydrogenase [Lactobacillus].	45.36	291	146	4	4	292	3	282	3e-69	228
rs:WP_009816470	5,10-methylene-tetrahydrofolate dehydrogenase [Roseovarius sp. 217].	45.58	294	149	3	1	292	1	285	3e-69	228
rs:WP_016318385	hypothetical protein [Firmicutes bacterium M10-2].	43.45	290	148	4	5	291	3	279	3e-69	228
rs:WP_003638599	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus].	46.05	291	144	5	4	292	3	282	3e-69	228
rs:WP_002973580	tetrahydrofolate dehydrogenase [Leptospira terpstrae].	39.80	294	163	3	2	295	3	282	4e-69	228
tr:U4Q459_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.21	292	152	4	3	290	2	289	4e-69	228
rs:WP_012998622	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces scabiei].	41.10	292	162	4	1	292	1	282	4e-69	228
rs:WP_038686936	methenyltetrahydrofolate cyclohydrolase [Rhizobium etli].	45.24	294	153	4	3	292	2	291	4e-69	228
tr:U4LA72_PYROM	SubName: Full=Similar to C-1-tetrahydrofolate synthase, mitochondrial acc. no. P09440 {ECO:0000313|EMBL:CCX07059.1};	44.75	295	156	3	1	292	1	291	4e-69	241
rs:XP_009538717	hypothetical protein PHYSODRAFT_307573 [Phytophthora sojae].	41.75	297	156	4	3	290	2	290	4e-69	228
rs:WP_038489842	methenyltetrahydrofolate cyclohydrolase [Agrobacterium tumefaciens].	44.41	295	156	4	3	293	2	292	4e-69	228
rs:WP_018216949	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora pacifica].	41.78	292	164	4	1	292	1	286	4e-69	228
rs:WP_009539281	methylenetetrahydrofolate dehydrogenase [Caenispirillum salinarum].	44.44	288	152	3	3	288	4	285	4e-69	228
rs:WP_041130854	methenyltetrahydrofolate cyclohydrolase [Streptomyces vietnamensis].	41.96	286	156	4	1	286	1	276	4e-69	228
rs:WP_004003538	bifunctional protein FolD 1 [Streptomyces viridochromogenes].	42.47	292	158	4	1	292	1	282	4e-69	228
rs:WP_003545582	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium leguminosarum].	45.70	291	150	4	5	291	4	290	4e-69	228
sp:FOLD2_SPHWW	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	48.10	289	143	3	2	290	13	294	4e-69	228
rs:WP_012693264	5,10-methylene-tetrahydrofolate dehydrogenase [Deinococcus deserti].	43.62	298	152	5	1	293	1	287	4e-69	228
rs:WP_025024028	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus nodensis].	43.75	288	151	4	4	291	2	278	4e-69	228
rs:WP_037176228	methenyltetrahydrofolate cyclohydrolase, partial [Rhizobium sp. Pop5].	45.39	293	152	4	4	292	3	291	4e-69	228
tr:A0A072PRW7_9EURO	SubName: Full=C-1-tetrahydrofolate synthase, mitochondrial {ECO:0000313|EMBL:KEF62512.1};	45.21	292	153	3	1	289	1	288	4e-69	241
rs:WP_022022169	bifunctional protein FolD [Acinetobacter sp. CAG:196].	44.48	281	140	5	5	284	2	267	4e-69	227
rs:XP_001903927	hypothetical protein [Podospora anserina S mat+].	43.88	294	158	3	1	291	130	419	4e-69	242
rs:WP_041078543	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Candidatus Rickettsia asemboensis].	41.67	288	157	3	4	290	3	280	4e-69	228
tr:I1QMY9_ORYGL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORGLA09G0041800.1};	44.33	291	156	2	2	290	96	382	4e-69	231
tr:W2WFT8_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETP08449.1};	43.14	306	156	7	2	293	45	346	4e-69	229
rs:WP_018927684	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas].	47.37	285	142	3	6	290	12	288	4e-69	228
rs:WP_045834809	methenyltetrahydrofolate cyclohydrolase [Hyphomicrobium sp. 99].	45.04	282	149	2	3	284	4	279	4e-69	228
tr:K0VYM7_9RHIZ	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EJZ16579.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EJZ16579.1}; Flags: Fragment;	45.39	293	152	4	4	292	4	292	4e-69	228
rs:NP_001062889	Os09g0327300 [Oryza sativa Japonica Group].	44.33	291	156	2	2	290	97	383	4e-69	231
rs:WP_039334588	methenyltetrahydrofolate cyclohydrolase [Novosphingobium subterraneum].	47.24	290	146	3	3	292	2	284	5e-69	228
rs:WP_028281030	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. H5].	41.55	296	164	5	1	292	1	291	5e-69	228
rs:WP_028940689	methenyltetrahydrofolate cyclohydrolase [Pseudomonas umsongensis].	47.74	287	139	5	6	290	12	289	5e-69	228
rs:WP_017959018	bifunctional protein FolD [Rhizobium leguminosarum].	45.21	292	152	4	5	292	4	291	5e-69	228
rs:WP_039258906	methenyltetrahydrofolate cyclohydrolase [Clostridium botulinum].	42.86	280	147	4	6	284	5	272	5e-69	227
rs:WP_003579490	bifunctional protein FolD [Lactobacillus casei].	45.10	286	146	3	6	291	5	279	5e-69	228
rs:WP_009379273	methylenetetrahydrofolate dehydrogenase [Brevibacterium casei].	42.57	296	161	6	1	292	1	291	5e-69	228
rs:WP_028931821	5,10-methylene-tetrahydrofolate cyclohydrolase [Pseudonocardia asaccharolytica].	42.41	290	156	3	1	290	1	279	5e-69	228
tr:A0A080ZKZ5_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETO67306.1};	43.14	306	156	7	2	293	45	346	5e-69	229
rs:WP_013288500	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Micromonospora].	42.12	292	163	4	1	292	1	286	5e-69	228
tr:W2MQL4_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETM38585.1};	43.14	306	156	7	2	293	45	346	5e-69	229
rs:WP_004945653	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces mobaraensis].	41.72	290	159	4	1	290	1	280	5e-69	228
rs:WP_010508563	5,10-methylene-tetrahydrofolate dehydrogenase [Komagataeibacter europaeus].	45.33	289	152	2	2	290	36	318	5e-69	229
tr:A0A0E0D1J8_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI03G18180.1};	44.33	291	156	2	2	290	96	382	5e-69	231
rs:WP_013039205	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium japonicum].	47.04	287	147	2	3	289	4	285	5e-69	228
rs:WP_021863453	bifunctional protein folD [Clostridium sp. CAG:715].	43.45	290	148	6	3	291	2	276	5e-69	227
rs:WP_045136303	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus paracasei].	44.76	286	147	3	6	291	5	279	5e-69	228
rs:WP_016383058	methylenetetrahydrofolate dehydrogenase [Lactobacillus paracasei].	44.76	286	147	3	6	291	5	279	5e-69	228
rs:WP_044901328	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas sp. CFII64].	45.61	285	147	3	6	290	11	287	5e-69	228
rs:WP_043692002	5,10-methylene-tetrahydrofolate cyclohydrolase [Synechococcus sp. KORDI-49].	46.29	283	142	3	6	288	5	277	5e-69	228
rs:WP_014376351	methenyltetrahydrofolate cyclohydrolase [Blastococcus saxobsidens].	44.14	290	151	2	1	290	1	279	5e-69	228
tr:W2G6U1_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETK78757.1};	43.71	302	152	7	2	289	45	342	5e-69	229
rs:WP_008067572	5,10-methylene-tetrahydrofolate dehydrogenase [Novosphingobium nitrogenifigens].	44.11	297	157	4	1	295	1	290	5e-69	228
rs:WP_004560598	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus delbrueckii].	43.10	290	153	4	3	292	2	279	5e-69	227
tr:W2YN61_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETP36485.1};	43.71	302	152	7	2	289	45	342	5e-69	229
rs:WP_021245798	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium baderi].	48.25	286	143	2	4	289	5	285	5e-69	228
tr:V9EJ37_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETI38533.1};	43.71	302	152	7	2	289	45	342	5e-69	229
rs:WP_023419051	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	41.61	286	157	4	1	286	1	276	5e-69	228
tr:C3K8G7_PSEFS	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.02	285	143	3	6	290	15	291	5e-69	228
tr:A0A0B2QL11_GLYSO	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KHN20417.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KHN20417.1}; EC=3.5.4.9 {ECO:0000313|EMBL:KHN20417.1};	47.52	242	121	2	54	293	2	239	5e-69	226
rs:WP_006313054	5,10-methylene-tetrahydrofolate dehydrogenase [Agrobacterium sp. ATCC 31749].	44.75	295	155	4	3	293	2	292	5e-69	228
rs:WP_026363662	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Agrobacterium].	44.41	295	156	4	3	293	2	292	5e-69	228
rs:WP_039256777	methenyltetrahydrofolate cyclohydrolase [Clostridium botulinum].	42.86	280	147	4	6	284	5	272	6e-69	227
rs:WP_030674640	methenyltetrahydrofolate cyclohydrolase [Streptomyces rimosus].	41.78	292	160	5	1	292	1	282	6e-69	227
rs:WP_029340123	methenyltetrahydrofolate cyclohydrolase [Geodermatophilaceae bacterium URHB0048].	42.31	286	154	4	1	286	1	275	6e-69	228
rs:WP_003602526	methylenetetrahydrofolate dehydrogenase [Lactobacillus casei].	45.10	286	146	3	6	291	5	279	6e-69	227
tr:S6H5K8_9PSED	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.61	285	147	3	6	290	11	287	6e-69	228
rs:WP_046800610	methenyltetrahydrofolate cyclohydrolase [Agrobacterium sp. LC34].	44.75	295	155	4	3	293	2	292	6e-69	228
tr:A0A0B7B862_9EUPU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CEK89504.1};	45.97	298	149	6	3	294	2	293	6e-69	241
tr:W0TE99_KLUMA	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:BAO41378.1};	44.75	295	153	4	5	293	3	293	6e-69	241
tr:H2SIZ8_TAKRU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTRUP00000012380}; Flags: Fragment;	43.92	296	153	6	3	291	3	292	6e-69	228
rs:WP_019220611	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella senegalensis].	44.71	293	150	5	5	291	4	290	6e-69	228
rs:WP_022489569	bifunctional protein FolD [Clostridium sp. CAG:914].	42.96	277	144	4	5	281	7	269	6e-69	227
rs:WP_003173310	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas fluorescens].	45.26	285	148	3	2	286	3	279	6e-69	228
tr:A0A0A1TF78_9HYPO	SubName: Full=Putative C-1-tetrahydrofolate synthase-like protein {ECO:0000313|EMBL:CEJ88534.1};	44.33	291	155	3	1	288	125	411	6e-69	241
rs:WP_022482726	bifunctional protein FolD [Clostridium sp. CAG:729].	44.21	285	143	6	3	286	2	271	6e-69	227
rs:WP_043205171	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	47.02	285	143	3	6	290	12	288	6e-69	228
rs:WP_041499606	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus heilongjiangensis].	42.76	290	155	4	1	290	3	281	6e-69	227
rs:WP_045726347	methenyltetrahydrofolate cyclohydrolase [Clostridium baratii].	42.01	288	156	2	4	291	3	279	6e-69	227
rs:XP_005978015	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Pantholops hodgsonii].	45.08	295	154	4	3	293	2	292	6e-69	228
tr:F2E1L3_HORVD	SubName: Full=Predicted protein {ECO:0000313|EMBL:BAK01235.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:MLOC_65637.1};	42.81	292	161	2	2	291	87	374	6e-69	230
rs:WP_018784672	5,10-methylene-tetrahydrofolate dehydrogenase [Micromonospora sp. CNB394].	42.12	292	163	4	1	292	1	286	6e-69	227
rs:XP_004200154	Piso0_002728 [Millerozyma farinosa CBS 7064].	44.63	298	156	4	1	293	1	294	7e-69	241
tr:V5B9G8_TRYCR	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:ESS69920.1};	41.36	295	165	3	3	293	4	294	7e-69	228
sp:FOLD_CHLAA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.61	293	164	2	1	293	1	283	7e-69	227
rs:WP_036542397	methenyltetrahydrofolate cyclohydrolase [Nitrincola lacisaponensis].	46.05	291	149	3	3	293	12	294	7e-69	228
rs:WP_029874065	bifunctional protein FolD [Rhizobium leguminosarum].	45.21	292	152	4	5	292	4	291	7e-69	228
rs:WP_028112718	methenyltetrahydrofolate cyclohydrolase [Ferrimonas kyonanensis].	44.15	299	156	5	2	297	3	293	7e-69	227
rs:XP_011616922	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Takifugu rubripes].	43.92	296	153	6	3	291	24	313	7e-69	228
rs:WP_026622374	methenyltetrahydrofolate cyclohydrolase [Ensifer sp. WSM1721].	45.42	295	151	6	3	292	2	291	7e-69	228
tr:A0A0C9UN24_9HOMO	SubName: Full=Unplaced genomic scaffold SPHSTscaffold_43, whole genome shotgun sequence {ECO:0000313|EMBL:KIJ44378.1};	45.30	298	153	4	3	294	7	300	7e-69	241
rs:WP_002987049	tetrahydrofolate dehydrogenase [Leptospira vanthielii].	40.14	294	162	3	2	295	3	282	7e-69	227
rs:WP_003961558	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces clavuligerus].	43.66	284	150	5	1	284	1	274	7e-69	227
rs:WP_045798936	5,10-methylene-tetrahydrofolate cyclohydrolase [Rickettsia bellii].	42.21	289	154	4	4	290	3	280	7e-69	227
tr:W5FEA7_WHEAT	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Traes_5BL_8747D4E40.2};	42.81	292	161	2	2	291	87	374	7e-69	230
rs:WP_006383492	tetrahydrofolate dehydrogenase [Streptomyces turgidiscabies].	41.10	292	162	4	1	292	1	282	7e-69	227
tr:M1PV81_9ZZZZ	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:AGF93024.1};	42.41	290	151	5	1	289	3	277	7e-69	227
rs:WP_013495590	5,10-methylene-tetrahydrofolate dehydrogenase [Thermaerobacter marianensis].	45.63	263	132	2	27	289	28	279	7e-69	228
rs:WP_037723398	methenyltetrahydrofolate cyclohydrolase [Streptomyces scabiei].	41.10	292	162	4	1	292	1	282	8e-69	227
tr:W0W1D7_ZYGBA	SubName: Full=Probable C-1-tetrahydrofolate synthase,cytoplasmic {ECO:0000313|EMBL:CDH15466.1};	45.12	297	153	4	1	291	1	293	8e-69	241
rs:WP_030829736	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-2305].	40.61	293	164	4	1	293	1	283	8e-69	227
rs:WP_035184674	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus delbrueckii].	43.10	290	153	4	3	292	2	279	8e-69	227
rs:XP_009846007	hypothetical protein H257_18610 [Aphanomyces astaci].	45.55	292	151	3	5	292	4	291	8e-69	228
rs:WP_031009038	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5727].	42.96	284	152	4	1	284	1	274	8e-69	227
tr:L0NCB9_RHISP	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.08	295	154	4	3	293	2	292	8e-69	228
tr:G8QAP1_PSEFL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.67	285	144	3	6	290	32	308	8e-69	228
rs:WP_010566662	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas extremaustralis].	47.37	285	142	3	6	290	12	288	8e-69	228
tr:A0A0D2K942_9EURO	SubName: Full=Unplaced genomic scaffold supercont1.2, whole genome shotgun sequence {ECO:0000313|EMBL:KIY02598.1};	44.86	292	154	3	1	289	1	288	8e-69	241
rs:WP_013853460	methenyltetrahydrofolate cyclohydrolase [Erysipelothrix rhusiopathiae].	41.61	286	155	3	5	290	4	277	8e-69	227
rs:WP_035209045	methenyltetrahydrofolate cyclohydrolase [Agrobacterium tumefaciens].	44.90	294	154	4	3	292	2	291	8e-69	228
rs:WP_035113756	methenyltetrahydrofolate cyclohydrolase [Corynebacterium auriscanis].	44.56	294	145	7	1	290	1	280	8e-69	227
rs:WP_010669003	5,10-methylene-tetrahydrofolate dehydrogenase [Acetobacter aceti].	45.89	292	152	2	2	293	20	305	8e-69	228
rs:WP_030764291	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-2664].	42.27	291	158	5	1	291	1	281	8e-69	227
rs:WP_026226890	methenyltetrahydrofolate cyclohydrolase [Hoeflea sp. 108].	46.74	291	146	4	5	292	4	288	8e-69	227
rs:XP_818429	C-1-tetrahydrofolate synthase, cytoplasmic [Trypanosoma cruzi strain CL Brener].	41.02	295	166	3	3	293	4	294	8e-69	227
rs:WP_030065598	methenyltetrahydrofolate cyclohydrolase [Streptomyces natalensis].	41.78	292	160	5	1	292	1	282	8e-69	227
rs:XP_011273026	C1-tetrahydrofolate synthase [Wickerhamomyces ciferrii].	42.52	294	162	3	1	291	1	290	8e-69	240
rs:WP_037464905	methenyltetrahydrofolate cyclohydrolase [Sphingobium herbicidovorans].	46.85	286	147	2	4	289	5	285	8e-69	227
rs:WP_004560828	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus delbrueckii].	43.10	290	153	4	3	292	2	279	8e-69	227
sp:FOLD_LACCB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.76	286	147	3	6	291	5	279	8e-69	227
rs:WP_010043835	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces chartreusis].	41.10	292	162	4	1	292	1	282	8e-69	227
rs:WP_024494026	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. AW19M42].	41.36	295	163	5	1	295	1	285	9e-69	227
rs:WP_004432568	5,10-methylene-tetrahydrofolate dehydrogenase [Agrobacterium tumefaciens].	44.75	295	155	4	3	293	2	292	9e-69	227
rs:WP_026544295	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. 35/47].	42.95	298	157	6	1	292	1	291	9e-69	227
sp:FOLD_PROM5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.01	288	162	2	6	293	5	287	9e-69	227
rs:WP_013328674	5,10-methylene-tetrahydrofolate dehydrogenase [Methanolacinia petrolearia].	45.49	288	141	6	5	291	2	274	9e-69	226
rs:WP_030687612	methenyltetrahydrofolate cyclohydrolase [Streptomyces globisporus].	41.61	286	157	4	1	286	1	276	9e-69	227
sp:FOLD_LACDB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.10	290	153	4	3	292	2	279	9e-69	227
rs:WP_013635487	5,10-methylene-tetrahydrofolate dehydrogenase [Agrobacterium sp. H13-3].	44.07	295	157	4	3	293	2	292	9e-69	227
rs:WP_025932041	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB241_528P14].	43.06	288	159	2	6	293	5	287	9e-69	227
rs:WP_021656370	tetrahydrofolate dehydrogenase [Clostridiales bacterium oral taxon 876].	41.87	289	157	2	5	293	4	281	9e-69	227
rs:WP_018493778	bifunctional protein FolD [Rhizobium leguminosarum].	45.21	292	152	4	5	292	4	291	9e-69	227
tr:A0A094Q570_9ZZZZ	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:KGA19310.1};	41.30	293	161	5	1	293	1	282	9e-69	227
tr:J7S2Z0_KAZNA	SubName: Full=KNAG0J02370 protein {ECO:0000313|EMBL:CCK72317.1};	45.70	291	151	3	6	293	25	311	9e-69	240
tr:K0N5K0_LACCA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.76	286	147	3	6	291	8	282	9e-69	227
rs:WP_026155617	methenyltetrahydrofolate cyclohydrolase [Paracoccus sp. N5].	43.79	290	155	3	3	292	2	283	9e-69	227
rs:WP_007671485	5,10-methylene-tetrahydrofolate dehydrogenase [Caulobacter sp. AP07].	43.69	293	157	2	3	291	4	292	9e-69	227
rs:WP_025942432	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus].	42.21	289	160	3	6	293	5	287	9e-69	227
rs:XP_009309488	C-1-tetrahydrofolate synthase, cytoplasmic [Trypanosoma grayi].	40.88	296	166	4	3	293	4	295	9e-69	227
rs:WP_017903947	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas fuscovaginae].	44.37	293	155	3	2	294	3	287	9e-69	227
tr:A0A0C2YHD5_HEBCY	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIM49113.1};	45.45	297	152	4	1	291	7	299	9e-69	240
rs:WP_037688222	methenyltetrahydrofolate cyclohydrolase [Streptomyces atratus].	41.58	291	160	5	1	291	1	281	9e-69	227
rs:WP_045021969	methenyltetrahydrofolate cyclohydrolase [Rhizobium nepotum].	44.41	295	156	4	3	293	2	292	9e-69	227
rs:WP_030174653	methenyltetrahydrofolate cyclohydrolase [Spirillospora albida].	42.81	292	156	4	1	292	1	281	9e-69	227
rs:WP_037261010	methenyltetrahydrofolate cyclohydrolase [Roseivivax halodurans].	44.52	292	156	2	1	292	1	286	1e-68	227
rs:WP_025425958	methenyltetrahydrofolate cyclohydrolase [Ensifer adhaerens].	45.70	291	150	4	5	291	4	290	1e-68	227
rs:XP_008895317	hypothetical protein PPTG_04776 [Phytophthora parasitica INRA-310].	42.81	306	157	7	2	293	45	346	1e-68	229
rs:WP_028061492	hypothetical protein [Solirubrobacter sp. URHD0082].	45.95	259	129	2	31	289	27	274	1e-68	226
rs:WP_039633536	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. 769].	41.44	292	161	5	1	292	1	282	1e-68	227
rs:WP_035241618	methenyltetrahydrofolate cyclohydrolase [Agrobacterium tumefaciens].	44.41	295	156	4	3	293	2	292	1e-68	227
rs:WP_026942417	methenyltetrahydrofolate cyclohydrolase [Hellea balneolensis].	43.60	289	155	2	1	289	1	281	1e-68	227
rs:XP_449418	hypothetical protein [Candida glabrata CBS 138].	43.99	291	157	2	5	293	13	299	1e-68	240
rs:XP_012478238	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X1 [Gossypium raimondii].	40.82	316	156	3	3	291	76	387	1e-68	230
rs:XP_012090958	PREDICTED: bifunctional protein FolD 1, mitochondrial [Jatropha curcas].	42.76	290	160	2	5	292	71	356	1e-68	229
rs:WP_037283523	methenyltetrahydrofolate cyclohydrolase [Rubellimicrobium mesophilum].	46.21	290	150	2	3	292	2	285	1e-68	227
rs:XP_002421614	C-1-tetrahydrofolate synthase, cytoplasmic, putative (EC 6.3.4.3); C1-THF synthase, putative; formyltetrahydrofolate synthetase, putative (EC 6.3.4.3); methenyltetrahydrofolate cyclohydrolase, putative (EC 3.5.4.9); methylenetetrahydrofolate dehydrogenase, putative (EC 1.5.1.5) [Candida dubliniensis CD36].	44.70	302	150	4	1	289	21	318	1e-68	240
rs:WP_027539390	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. URHA0002].	44.64	289	154	2	1	289	1	283	1e-68	227
rs:WP_030368195	methenyltetrahydrofolate cyclohydrolase [Streptomyces roseoverticillatus].	40.75	292	163	4	1	292	1	282	1e-68	227
rs:WP_047138778	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. KE1].	41.96	286	156	5	1	286	1	276	1e-68	227
rs:WP_013269693	5,10-methylene-tetrahydrofolate dehydrogenase [Brevundimonas subvibrioides].	43.88	294	157	2	3	292	8	297	1e-68	227
rs:WP_025973950	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Prochlorococcus sp. scB241_529B19].	43.21	280	152	3	15	293	5	278	1e-68	227
tr:A0A0D1YLV8_9EURO	SubName: Full=Exophiala sideris strain CBS 121828 unplaced genomic scaffold supercont1.2, whole genome shotgun sequence {ECO:0000313|EMBL:KIV82024.1};	44.18	292	156	3	1	289	96	383	1e-68	241
rs:XP_007032236	Amino acid dehydrogenase family protein isoform 5 [Theobroma cacao].	43.89	262	141	2	32	291	7	264	1e-68	226
rs:WP_018550513	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. ATexAB-D23].	42.31	286	155	5	1	286	1	276	1e-68	227
rs:WP_016734764	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium phaseoli].	45.55	292	151	4	5	292	4	291	1e-68	227
rs:XP_012275956	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Orussus abietinus].	43.73	295	157	3	3	291	27	318	1e-68	228
rs:WP_030004080	bifunctional protein FolD [Acholeplasma brassicae].	43.26	282	148	3	5	286	2	271	1e-68	226
gpu:LN483124_88	fthfs-domain-containing protein [Xanthophyllomyces dendrorhous]	44.75	295	153	4	3	291	22	312	1e-68	240
tr:W8I4J4_ENSAD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.70	291	150	4	5	291	15	301	1e-68	227
rs:WP_033177872	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. URHA0041].	43.31	284	151	5	1	284	1	274	1e-68	226
rs:WP_008619643	5,10-methylene-tetrahydrofolate dehydrogenase [Magnetospirillum sp. SO-1].	45.17	290	153	2	3	292	4	287	1e-68	227
rs:WP_002300043	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Streptococcus mutans].	55.29	208	83	3	86	293	1	198	1e-68	224
rs:WP_022427550	bifunctional protein FolD [Ruminococcus sp. CAG:403].	41.81	287	157	2	6	292	5	281	1e-68	226
tr:A0A061B8P4_CYBFA	SubName: Full=CYFA0S22e02168g1_1 {ECO:0000313|EMBL:CDR46289.1};	43.64	291	157	3	6	293	21	307	1e-68	240
rs:WP_039616438	methenyltetrahydrofolate cyclohydrolase [Rhodobacteraceae bacterium PD-2].	45.05	293	156	2	1	292	1	289	1e-68	227
rs:WP_030128794	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. QTF5].	47.04	287	141	5	6	290	15	292	1e-68	227
rs:WP_003503342	5,10-methylene-tetrahydrofolate dehydrogenase [Agrobacterium tumefaciens].	44.56	294	155	4	3	292	2	291	1e-68	227
rs:WP_020813066	5,10-methylene-tetrahydrofolate dehydrogenase [Agrobacterium tumefaciens].	44.56	294	155	4	3	292	2	291	1e-68	227
rs:WP_023016802	MULTISPECIES: FolD protein [Corynebacterium].	41.92	291	158	4	1	291	1	280	1e-68	226
rs:WP_014940011	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus buchneri].	44.37	293	151	4	3	293	2	284	1e-68	226
tr:A0A087ULP0_9ARAC	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFM78279.1}; Flags: Fragment;	43.39	295	158	4	5	294	52	342	1e-68	228
rs:WP_008470857	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus hominis].	44.18	292	151	4	3	294	2	281	1e-68	226
rs:WP_027876130	methenyltetrahydrofolate cyclohydrolase [Meiothermus cerbereus].	43.97	282	148	4	6	287	4	275	1e-68	226
rs:XP_007926092	hypothetical protein MYCFIDRAFT_163981 [Pseudocercospora fijiensis CIRAD86].	44.18	292	156	3	1	289	73	360	1e-68	240
rs:WP_016745422	bifunctional protein FolD [Sphingomonas wittichii].	47.75	289	144	3	2	290	13	294	1e-68	227
rs:WP_036986612	methenyltetrahydrofolate cyclohydrolase [Pseudogulbenkiania sp. MAI-1].	49.62	262	123	4	34	292	37	292	1e-68	227
rs:WP_006557117	5,10-methylene-tetrahydrofolate dehydrogenase [Acetobacter tropicalis].	44.98	289	153	2	2	290	12	294	1e-68	227
rs:WP_019852942	5,10-methylene-tetrahydrofolate dehydrogenase [Actinopolyspora mortivallis].	41.78	292	159	5	1	292	1	281	1e-68	226
rs:WP_040971907	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. ORS3324].	46.23	292	147	5	5	292	4	289	1e-68	227
sp:FOLD_RHOP2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.33	289	153	2	1	289	1	284	1e-68	227
rs:WP_014249070	5,10-methylene-tetrahydrofolate dehydrogenase [Azospirillum lipoferum].	46.34	287	145	5	3	286	4	284	1e-68	227
rs:WP_020801138	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas].	45.21	292	138	4	6	290	12	288	1e-68	227
rs:WP_006521740	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfotomaculum gibsoniae].	41.72	290	158	3	1	290	1	279	1e-68	226
rs:WP_033036472	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. GM102].	47.39	287	140	5	6	290	15	292	1e-68	227
rs:WP_045246013	methenyltetrahydrofolate cyclohydrolase [Thermus filiformis].	44.60	287	143	4	3	289	10	280	1e-68	226
rs:WP_010423077	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia helvetica].	40.89	291	161	3	4	293	3	283	1e-68	226
rs:WP_027603575	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. LAMO17WK12:I2].	45.99	287	146	4	1	286	1	279	1e-68	227
rs:WP_030478421	methenyltetrahydrofolate cyclohydrolase [Lentzea albidocapillata].	42.47	292	154	5	1	292	1	278	1e-68	226
rs:XP_003669784	hypothetical protein NDAI_0D02270 [Naumovozyma dairenensis CBS 421].	42.81	299	161	4	1	293	1	295	2e-68	240
rs:WP_013345570	5,10-methylene-tetrahydrofolate dehydrogenase [Ferrimonas balearica].	44.03	293	153	5	3	292	10	294	2e-68	226
rs:XP_007748454	formate-tetrahydrofolate ligase [Cladophialophora psammophila CBS 110553].	44.86	292	154	3	1	289	1	288	2e-68	240
rs:WP_030318483	methenyltetrahydrofolate cyclohydrolase [Streptomyces flavochromogenes].	41.96	286	156	4	1	286	1	276	2e-68	226
tr:A0A0C7N0Z9_9SACH	SubName: Full=LALA0S09e03180g1_1 {ECO:0000313|EMBL:CEP63817.1};	42.09	297	153	4	6	293	41	327	2e-68	240
rs:WP_032831759	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. GM78].	46.67	285	144	3	6	290	12	288	2e-68	227
rs:WP_018830679	bifunctional protein FolD [Salinispora tropica].	41.78	292	164	4	1	292	1	286	2e-68	226
rs:WP_025963293	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB241_526D20].	41.87	289	161	3	6	293	5	287	2e-68	226
sp:FOLD_SYNS3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.52	283	147	3	6	288	5	277	2e-68	226
tr:A3BXI3_ORYSJ	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EAZ44272.1};	44.33	291	156	2	2	290	132	418	2e-68	231
tr:F0K3D7_LACD2	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.10	290	153	4	3	292	14	291	2e-68	226
sp:FOLD2_FRASC	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.15	292	155	3	1	292	1	281	2e-68	226
rs:WP_022555632	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium sp. H41].	44.56	294	155	4	3	292	2	291	2e-68	226
sp:FOLD2_SALTO	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.78	292	164	4	1	292	1	286	2e-68	226
rs:WP_029026858	methenyltetrahydrofolate cyclohydrolase [Salinispora arenicola].	41.44	292	165	4	1	292	1	286	2e-68	226
rs:WP_030494347	methenyltetrahydrofolate cyclohydrolase [Microtetraspora glauca].	42.31	286	155	4	1	286	1	276	2e-68	226
rs:WP_039104779	methenyltetrahydrofolate cyclohydrolase [Lactobacillus brevis].	45.77	284	141	5	5	286	4	276	2e-68	226
rs:WP_032514187	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus marinus].	42.36	288	161	2	6	293	5	287	2e-68	226
rs:WP_018929003	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas].	47.39	287	140	5	6	290	12	289	2e-68	227
rs:WP_034582891	methenyltetrahydrofolate cyclohydrolase [Acinetobacter sp. HR7].	46.05	291	146	5	2	290	10	291	2e-68	226
rs:WP_035106658	methenyltetrahydrofolate cyclohydrolase [Corynebacterium camporealensis].	43.88	294	148	5	1	291	1	280	2e-68	226
rs:WP_018653601	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomadura flavalba].	41.30	293	161	4	1	293	1	282	2e-68	226
tr:W2IF96_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETL32192.1};	42.81	306	157	7	2	293	45	346	2e-68	228
tr:J3IFP7_9PSED	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576}; Flags: Precursor;	46.67	285	144	3	6	290	27	303	2e-68	227
rs:WP_003714771	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus oris].	44.56	285	143	6	5	286	2	274	2e-68	226
rs:WP_037114491	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Rhizobium].	45.55	292	151	4	5	292	4	291	2e-68	226
tr:A0A024H284_9MICC	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.56	289	155	2	2	290	3	280	2e-68	226
rs:WP_019578751	methenyltetrahydrofolate cyclohydrolase [Pseudomonas mandelii].	47.04	287	141	5	6	290	12	289	2e-68	227
tr:A0A060SKH5_PYCCI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CDO72918.1};	46.10	295	149	4	3	291	8	298	2e-68	239
rs:WP_008013469	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. GM50].	47.39	287	140	5	6	290	15	292	2e-68	227
rs:XP_007709466	hypothetical protein COCCADRAFT_23976 [Bipolaris zeicola 26-R-13].	44.52	292	155	3	1	289	1	288	2e-68	239
rs:WP_008442277	5,10-methylene-tetrahydrofolate dehydrogenase [Thermoplasmatales archaeon SCGC AB-539-N05].	39.79	289	163	2	5	293	4	281	2e-68	226
rs:WP_013727958	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus buchneri].	44.37	293	151	4	3	293	2	284	2e-68	226
rs:WP_028035575	methenyltetrahydrofolate cyclohydrolase [Chelativorans sp. J32].	44.91	285	148	4	5	288	11	287	2e-68	226
tr:A0A0C9R296_AMBAM	SubName: Full=TSA: Amblyomma americanum Aam-35509 mRNA sequence {ECO:0000313|EMBL:JAG91140.1}; Flags: Fragment;	44.26	296	156	4	3	293	1	292	2e-68	226
rs:WP_034993808	methenyltetrahydrofolate cyclohydrolase [Beijerinckia mobilis].	43.38	302	156	6	2	293	7	303	2e-68	226
rs:WP_023025319	MULTISPECIES: FolD protein [Corynebacterium].	43.30	291	154	4	1	291	1	280	2e-68	226
rs:WP_027573075	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. WSM1743].	44.64	289	154	2	1	289	1	283	2e-68	226
tr:F6ISC2_LACPE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.36	291	146	5	4	292	6	285	2e-68	226
rs:WP_018315799	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobium sp. WSM2793].	44.33	291	155	3	1	290	1	285	2e-68	226
rs:WP_028721363	hypothetical protein [Patulibacter americanus].	42.96	284	151	2	6	289	1	273	2e-68	226
rs:XP_007784029	C-1-tetrahydrofolate synthase, cytoplasmic [Coniosporium apollinis CBS 100218].	44.86	292	154	3	1	289	1	288	2e-68	239
rs:WP_003985826	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	41.78	292	160	5	1	292	1	282	2e-68	226
rs:WP_008856851	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus kisonensis].	42.66	293	156	4	3	293	2	284	2e-68	226
rs:WP_018318964	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobium sp. WSM2793].	44.29	289	155	2	1	289	1	283	2e-68	226
rs:WP_028303996	methenyltetrahydrofolate cyclohydrolase [Oceanospirillum maris].	43.21	287	156	2	6	292	5	284	2e-68	226
sp:FOLD_LACDA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.10	290	153	4	3	292	2	279	2e-68	226
tr:A0A024FZM4_9STRA	SubName: Full=Albugo candida WGS project CAIX00000000 data, strain Ac Nc2, contig AcNc2_CONTIG_4_length_286395 {ECO:0000313|EMBL:CCI39852.1};	42.95	298	151	5	5	293	2	289	2e-68	226
tr:F0WDC7_9STRA	SubName: Full=Bifunctional folD protein putative {ECO:0000313|EMBL:CCA19199.1};	44.30	298	147	6	5	293	2	289	2e-68	226
rs:XP_006429682	hypothetical protein CICLE_v10012007mg [Citrus clementina].	45.86	266	135	3	32	292	7	268	2e-68	225
rs:WP_037919092	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. PCS3-D2].	42.12	292	159	5	1	292	1	282	2e-68	226
tr:A0A0A8EKY0_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.44	292	161	5	1	292	26	307	2e-68	226
rs:WP_004854171	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella doshiae].	44.75	295	149	6	4	291	3	290	2e-68	226
rs:WP_012482703	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium etli].	45.55	292	151	4	5	292	4	291	2e-68	226
rs:WP_020490781	5,10-methylene-tetrahydrofolate dehydrogenase [Dehalobacter sp. FTH1].	42.31	286	154	4	1	286	1	275	2e-68	226
rs:WP_025229230	hypothetical protein [Fimbriimonas ginsengisoli].	43.69	293	155	3	1	293	1	283	2e-68	226
rs:XP_005965334	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Pantholops hodgsonii].	43.15	292	158	2	4	291	5	292	2e-68	226
rs:WP_005684395	tetrahydrofolate dehydrogenase [Lactobacillus rhamnosus].	43.60	289	152	3	6	294	5	282	2e-68	226
rs:WP_043293248	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. LAMO17WK12:I2].	46.67	285	144	3	6	290	12	288	2e-68	226
rs:WP_045023444	methenyltetrahydrofolate cyclohydrolase [Agrobacterium sp. KFB 330].	42.56	289	159	2	1	289	1	282	2e-68	226
tr:C2JXV8_LACRH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.60	289	152	3	6	294	8	285	2e-68	226
rs:XP_002905441	bifunctional folD protein [Phytophthora infestans T30-4].	42.47	299	153	6	5	289	9	302	2e-68	226
tr:F7U4Z1_RHIRD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.37	293	155	4	5	293	1	289	2e-68	226
tr:A0A0D6A2V8_9LACO	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:BAQ57024.1};	44.37	293	149	5	1	292	12	291	2e-68	226
rs:WP_030024562	methenyltetrahydrofolate cyclohydrolase [Streptomyces monomycini].	42.12	292	159	5	1	292	1	282	2e-68	226
rs:WP_009322452	5,10-methylene-tetrahydrofolate dehydrogenase [Subdoligranulum sp. 4_3_54A2FAA].	49.02	255	120	2	36	290	34	278	2e-68	226
sp:FOLD_CAUSK	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.34	293	158	2	3	291	4	292	2e-68	226
tr:W4ZX77_WHEAT	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Traes_1AS_8CA404D17.1};	47.52	242	121	2	54	293	2	239	2e-68	224
sp:FOLD_AGRT5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.41	295	156	4	3	293	2	292	2e-68	226
rs:WP_008854787	5,10-methylene-tetrahydrofolate dehydrogenase [Commensalibacter intestini].	43.54	294	159	3	1	293	5	292	2e-68	226
rs:WP_044833271	methenyltetrahydrofolate cyclohydrolase [Thalassomonas actiniarum].	43.75	288	154	4	6	291	3	284	2e-68	226
rs:WP_039996610	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sanxanigenens].	45.30	287	150	3	5	291	4	283	2e-68	226
rs:WP_030695854	methenyltetrahydrofolate cyclohydrolase [Streptomyces griseus].	41.96	286	156	5	1	286	1	276	2e-68	226
rs:WP_005575801	5,10-methylene-tetrahydrofolate dehydrogenase [Natronobacterium gregoryi].	45.45	286	154	2	4	289	3	286	3e-68	226
rs:WP_010351811	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces acidiscabies].	41.10	292	162	4	1	292	1	282	3e-68	226
rs:WP_045022056	methenyltetrahydrofolate cyclohydrolase [Agrobacterium sp. KFB 330].	44.07	295	157	4	3	293	2	292	3e-68	226
tr:A0A0E0B1G9_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM09G06380.1};	44.33	291	156	2	2	290	97	383	3e-68	229
rs:XP_008779697	PREDICTED: bifunctional protein FolD 1, mitochondrial, partial [Phoenix dactylifera].	41.72	290	163	2	5	292	8	293	3e-68	226
rs:WP_030540140	methenyltetrahydrofolate cyclohydrolase [Sphingobium sp. DC-2].	47.20	286	146	2	4	289	5	285	3e-68	226
rs:WP_008031692	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodobacter sp. SW2].	48.11	291	144	2	1	291	1	284	3e-68	226
rs:WP_015758077	methylenetetrahydrofolate dehydrogenase [Desulfotomaculum acetoxidans].	42.66	293	153	4	1	290	1	281	3e-68	226
tr:J3DWZ7_9PSED	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576}; Flags: Precursor;	47.39	287	140	5	6	290	26	303	3e-68	227
tr:S2QZE7_LACPA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.76	286	147	3	6	291	5	279	3e-68	226
rs:WP_021319470	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium ummariense].	47.90	286	144	2	4	289	5	285	3e-68	226
tr:X8JF27_9HOMO	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:EUC62332.1};	44.59	296	152	5	3	290	92	383	3e-68	239
rs:WP_004440039	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium/Agrobacterium group].	44.90	294	154	4	3	292	2	291	3e-68	226
rs:WP_036002869	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium yuanmingense].	44.29	289	155	2	1	289	1	283	3e-68	226
rs:WP_043328369	methenyltetrahydrofolate cyclohydrolase [Micromonospora sp. M42].	41.78	292	164	4	1	292	1	286	3e-68	226
rs:XP_012707750	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Fundulus heteroclitus].	46.31	298	151	4	1	293	1	294	3e-68	239
rs:WP_030221349	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL WC-3626].	40.61	293	164	4	1	293	1	283	3e-68	225
rs:WP_029009525	methenyltetrahydrofolate cyclohydrolase [Azospirillum halopraeferens].	45.55	292	152	4	3	292	4	290	3e-68	226
tr:A0A078MRB7_9MICC	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.75	297	165	5	1	293	36	328	3e-68	227
rs:WP_032523562	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus marinus].	42.36	288	161	2	6	293	5	287	3e-68	226
rs:WP_008076469	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. GM79].	47.39	287	140	5	6	290	15	292	3e-68	226
tr:A0A059AEW9_EUCGR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KCW52294.1};	39.12	294	173	2	2	293	70	359	3e-68	228
rs:WP_043444613	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. L77].	40.88	296	162	6	2	291	4	292	3e-68	226
rs:WP_019651624	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas sp. 45MFCol3.1].	47.04	287	141	5	6	290	12	289	3e-68	226
rs:XP_008712177	hypothetical protein HMPREF1541_09280 [Cyphellophora europaea CBS 101466].	43.49	292	158	3	1	289	1	288	3e-68	239
rs:WP_004505067	tetrahydrofolate dehydrogenase [Leptospira weilii].	39.32	295	165	2	1	295	1	281	3e-68	225
rs:WP_045205864	methenyltetrahydrofolate cyclohydrolase [Burkholderiaceae bacterium 26].	43.64	291	158	2	1	291	1	285	3e-68	226
rs:WP_044585657	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. LTSPM299].	44.56	285	148	3	1	285	1	275	3e-68	226
rs:WP_042443231	methenyltetrahydrofolate cyclohydrolase [Azospirillum lipoferum].	46.53	288	143	6	3	286	4	284	3e-68	226
rs:XP_007586726	putative c1 tetrahydrofolate protein [Neofusicoccum parvum UCRNP2].	43.84	292	157	3	1	289	1	288	3e-68	239
rs:XP_806444	C-1-tetrahydrofolate synthase, cytoplasmic [Trypanosoma cruzi strain CL Brener].	40.68	295	167	3	3	293	4	294	3e-68	226
rs:WP_029021907	methenyltetrahydrofolate cyclohydrolase [Salinispora arenicola].	41.44	292	165	4	1	292	1	286	3e-68	225
rs:WP_035181950	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus farciminis].	42.76	290	155	4	1	290	3	281	3e-68	225
tr:A0A060T747_BLAAD	SubName: Full=ARAD1C25828p {ECO:0000313|EMBL:CDP35021.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CDP35021.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CDP35021.1}; EC=6.3.4.3 {ECO:0000313|EMBL:CDP35021.1};	44.86	292	154	3	2	290	36	323	3e-68	239
rs:WP_033357597	methenyltetrahydrofolate cyclohydrolase [Dactylosporangium aurantiacum].	41.84	294	161	5	1	292	1	286	3e-68	225
rs:WP_016384666	bifunctional protein FolD [Lactobacillus paracasei].	44.41	286	148	3	6	291	5	279	3e-68	225
tr:A0A0A6LUP8_CANAL	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KHC77144.1};	43.92	296	157	4	1	291	1	292	3e-68	239
rs:WP_030051636	methenyltetrahydrofolate cyclohydrolase [Streptomyces peruviensis].	41.64	293	161	4	1	293	1	283	3e-68	225
tr:A0A0D2CY93_9EURO	SubName: Full=Strain CBS 83496 unplaced genomic scaffold supercont1.4, whole genome shotgun sequence {ECO:0000313|EMBL:KIW28534.1};	45.21	292	153	3	1	289	117	404	3e-68	239
tr:K1YNE0_9BACT	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKD38582.1}; Flags: Fragment;	52.23	224	105	1	72	293	5	228	4e-68	223
rs:WP_035197883	methenyltetrahydrofolate cyclohydrolase [Agrobacterium tumefaciens].	44.07	295	157	4	3	293	2	292	4e-68	226
tr:A0A0A6K8E6_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KHC28500.1};	43.92	296	157	4	1	291	1	292	4e-68	239
rs:WP_003690061	tetrahydrofolate dehydrogenase [Lactobacillus mali].	46.53	288	143	3	4	291	3	279	4e-68	225
rs:WP_024809438	methenyltetrahydrofolate cyclohydrolase [Oceanicola sp. HL-35].	44.52	292	156	2	1	292	1	286	4e-68	226
tr:A0A0E0LZW4_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC09G05110.1};	43.99	291	157	2	2	290	94	380	4e-68	229
rs:WP_040408315	methenyltetrahydrofolate cyclohydrolase [Aureimonas ureilytica].	45.08	295	153	5	2	292	9	298	4e-68	226
rs:XP_001483356	conserved hypothetical protein [Meyerozyma guilliermondii ATCC 6260].	43.84	292	155	4	5	291	3	290	4e-68	239
rs:WP_030280926	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	43.64	291	153	5	1	291	1	280	4e-68	225
rs:XP_012757886	hypothetical protein SAMD00019534_018410, partial [Acytostelium subglobosum LB1].	39.18	291	170	3	6	290	198	487	4e-68	231
rs:WP_020812906	5,10-methylene-tetrahydrofolate dehydrogenase [Agrobacterium tumefaciens].	44.56	294	155	4	3	292	2	291	4e-68	226
rs:WP_005715494	methylenetetrahydrofolate dehydrogenase [Lactobacillus rhamnosus].	43.25	289	153	3	6	294	5	282	4e-68	225
tr:D7TKV5_VITVI	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CBI31127.3};	41.98	293	164	2	2	292	66	354	4e-68	228
rs:WP_036645572	methenyltetrahydrofolate cyclohydrolase [Pantoea sp. A4].	46.18	288	148	3	3	290	7	287	4e-68	226
tr:A0A0C1V2U6_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.64	289	154	2	2	290	14	296	4e-68	226
tr:A0A061BKR6_CYBFA	SubName: Full=CYFA0S34e00694g1_1 {ECO:0000313|EMBL:CDR47610.1};	43.54	294	159	3	3	293	66	355	4e-68	239
rs:WP_032963691	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus rhamnosus].	43.60	289	152	3	6	294	5	282	4e-68	225
rs:XP_008723624	hypothetical protein G647_02003 [Cladophialophora carrionii CBS 160.54].	44.52	292	155	3	1	289	1	288	4e-68	238
rs:WP_029329327	methenyltetrahydrofolate cyclohydrolase [Komagataeibacter oboediens].	44.64	289	154	2	2	290	14	296	4e-68	226
tr:B3TA01_9ZZZZ	SubName: Full=Putative Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:ABZ09410.1};	46.23	292	139	7	1	292	1	274	4e-68	225
rs:WP_036381975	methenyltetrahydrofolate cyclohydrolase [Micrococcus luteus].	40.80	299	161	7	1	292	1	290	4e-68	226
rs:WP_036338210	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Bacteria].	40.80	299	161	7	1	292	1	290	4e-68	226
rs:WP_030501498	methenyltetrahydrofolate cyclohydrolase [Micromonospora purpureochromogenes].	41.78	292	164	4	1	292	1	286	4e-68	225
rs:XP_009049161	hypothetical protein LOTGIDRAFT_201055 [Lottia gigantea].	44.41	295	153	5	3	291	2	291	4e-68	238
rs:WP_045388271	methenyltetrahydrofolate cyclohydrolase [Falsirhodobacter sp. alg1].	45.21	292	149	3	1	292	1	281	4e-68	225
rs:WP_017976680	5,10-methylene-tetrahydrofolate dehydrogenase [Actinopolyspora halophila].	41.10	292	161	5	1	292	1	281	4e-68	225
rs:WP_046782989	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus rhamnosus].	43.60	289	152	3	6	294	5	282	4e-68	225
rs:WP_019032986	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora arenicola].	41.44	292	165	4	1	292	1	286	4e-68	225
rs:WP_046263191	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. WM6386].	40.75	292	163	4	1	292	1	282	5e-68	225
rs:WP_007014679	5,10-methylene-tetrahydrofolate dehydrogenase [Novosphingobium pentaromativorans].	46.37	289	148	3	5	293	4	285	5e-68	225
tr:A0A059WZT9_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.91	296	158	4	1	292	1	289	5e-68	225
rs:WP_006852279	methenyltetrahydrofolate cyclohydrolase [Synechococcus sp. WH 8016].	44.17	283	148	3	6	288	5	277	5e-68	225
tr:X0QSR5_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.92	291	158	3	2	292	7	286	5e-68	225
rs:XP_007692857	hypothetical protein COCMIDRAFT_9531 [Bipolaris oryzae ATCC 44560].	44.18	292	156	3	1	289	1	288	5e-68	238
rs:WP_022492311	bifunctional protein FolD [Clostridium sp. CAG:813].	43.99	291	146	7	5	293	4	279	5e-68	225
rs:WP_012732194	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium kroppenstedtii].	43.16	285	149	6	3	286	2	274	5e-68	225
rs:XP_005452569	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like isoform X1 [Oreochromis niloticus].	43.73	295	155	5	3	291	24	313	5e-68	226
rs:WP_042702264	methenyltetrahydrofolate cyclohydrolase [Azospirillum sp. B506].	46.53	288	143	6	3	286	4	284	5e-68	225
sp:FOLD2_SALAI	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.44	292	165	4	1	292	1	286	5e-68	225
rs:WP_013500095	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodopseudomonas palustris].	44.98	289	154	2	1	289	1	284	5e-68	225
sp:FOLD_LACC3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.41	286	148	3	6	291	5	279	5e-68	225
rs:WP_020594502	hypothetical protein [Kiloniella laminariae].	44.86	292	150	4	2	289	3	287	5e-68	225
rs:WP_025933677	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB243_498A3].	43.06	288	159	2	6	293	5	287	5e-68	225
rs:WP_038983716	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fluorescens].	47.04	287	141	5	6	290	15	292	5e-68	226
rs:WP_025930495	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB241_528O2].	42.91	289	158	4	6	293	5	287	5e-68	225
tr:C2FF28_LACPA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.41	286	148	3	6	291	8	282	5e-68	225
tr:D3NY52_AZOS1	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.53	288	143	6	3	286	13	293	5e-68	226
rs:WP_015796527	5,10-methylene-tetrahydrofolate dehydrogenase [Catenulispora acidiphila].	39.93	293	165	5	1	293	1	282	5e-68	225
rs:WP_030059152	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	43.30	291	154	5	1	291	1	280	5e-68	225
rs:XP_007694097	hypothetical protein COCSADRAFT_22292 [Bipolaris sorokiniana ND90Pr].	44.18	292	156	3	1	289	1	288	5e-68	238
rs:WP_016570520	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	41.44	292	161	5	1	292	1	282	5e-68	225
sp:FOLD_SYNSC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.83	284	139	5	6	288	5	277	5e-68	225
rs:WP_038602016	methenyltetrahydrofolate cyclohydrolase [Rickettsiales bacterium Ac37b].	43.99	291	152	3	4	292	3	284	5e-68	225
rs:WP_045301397	methenyltetrahydrofolate cyclohydrolase [Saccharothrix sp. ST-888].	42.27	291	158	4	1	291	1	281	5e-68	225
rs:WP_035377538	hypothetical protein [Fervidicella metallireducens].	42.56	289	155	2	1	289	1	278	5e-68	225
rs:WP_026533164	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. H41].	41.75	297	160	6	2	292	4	293	5e-68	225
rs:XP_005753695	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Pundamilia nyererei].	44.07	295	154	5	3	291	24	313	5e-68	226
rs:WP_010342914	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Xanthomonas sacchari].	49.80	251	114	3	44	292	2	242	6e-68	224
rs:WP_044010723	methenyltetrahydrofolate cyclohydrolase [Lactobacillus sp. WDC04].	43.10	290	152	4	5	292	4	282	6e-68	225
rs:WP_021697805	methylenetetrahydrofolate dehydrogenase [Brevundimonas abyssalis].	44.22	294	156	2	3	292	4	293	6e-68	225
rs:WP_004619656	5,10-methylene-tetrahydrofolate dehydrogenase [Caulobacter vibrioides].	43.15	292	158	2	4	291	5	292	6e-68	225
tr:G3PKR7_GASAC	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGACP00000018197};	43.96	298	154	6	3	293	24	315	6e-68	226
rs:WP_006698179	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium lupini].	44.56	294	155	4	3	292	2	291	6e-68	225
rs:WP_004462773	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira santarosai].	40.00	295	163	2	1	295	1	281	6e-68	224
rs:WP_041870876	methenyltetrahydrofolate cyclohydrolase [Bdellovibrio sp. ArHS].	42.16	287	157	2	5	291	3	280	6e-68	224
rs:WP_025725036	methenyltetrahydrofolate cyclohydrolase [Acholeplasma granularum].	42.86	280	145	3	5	284	2	266	6e-68	224
rs:WP_013557095	5,10-methylene-tetrahydrofolate dehydrogenase [Deinococcus maricopensis].	47.33	262	127	4	36	295	32	284	6e-68	224
tr:W5UF17_ICTPU	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:AHH40164.1};	44.97	298	155	4	1	293	1	294	6e-68	238
rs:WP_015678287	tetrahydrofolate dehydrogenase [Leptospira yanagawae].	40.48	294	161	3	2	295	3	282	6e-68	225
tr:W4Y3C3_STRPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:SPU_010209-tr};	49.17	240	114	4	61	293	1	239	6e-68	223
rs:WP_017131175	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudomonas agarici].	47.02	285	143	4	6	290	11	287	6e-68	225
rs:WP_025645821	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Psychrobacter].	42.81	292	154	5	2	292	16	295	6e-68	225
rs:WP_025886410	methenyltetrahydrofolate cyclohydrolase [Asaia prunellae].	44.11	297	160	2	1	297	7	297	6e-68	225
rs:WP_039734097	methenyltetrahydrofolate cyclohydrolase [Komagataeibacter intermedius].	44.64	289	154	2	2	290	36	318	6e-68	226
rs:WP_025439819	methenyltetrahydrofolate cyclohydrolase [Komagataeibacter xylinus].	45.14	288	152	2	3	290	15	296	6e-68	225
rs:WP_027363448	methenyltetrahydrofolate cyclohydrolase [Desulfotomaculum alcoholivorax].	40.69	290	161	3	1	290	1	279	6e-68	224
sp:FOLD_BUCCC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.75	256	137	2	34	289	34	282	6e-68	224
rs:XP_002264477	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X1 [Vitis vinifera].	41.98	293	164	2	2	292	79	367	6e-68	227
rs:WP_024515064	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. Tv2a-2].	44.29	289	155	2	1	289	1	283	6e-68	225
rs:WP_026479363	methenyltetrahydrofolate cyclohydrolase [Ahrensia sp. 13_GOM-1096m].	45.24	294	153	4	3	292	2	291	6e-68	225
rs:WP_010199000	5,10-methylene-tetrahydrofolate dehydrogenase [Psychrobacter sp. PAMC 21119].	41.92	291	158	2	2	292	10	289	6e-68	225
rs:WP_012993662	methenyltetrahydrofolate cyclohydrolase [Mageeibacillus indolicus].	45.49	288	143	4	1	285	1	277	7e-68	225
rs:WP_010503525	5,10-methylene-tetrahydrofolate dehydrogenase [Gluconobacter frateurii].	44.18	292	157	2	1	292	8	293	7e-68	225
tr:I2K3P9_DEKBR	SubName: Full=C-1-tetrahydrofolate mitochondrial {ECO:0000313|EMBL:EIF49851.1};	43.54	294	159	3	1	291	39	328	7e-68	238
rs:WP_034124074	methenyltetrahydrofolate cyclohydrolase [Peptococcaceae bacterium BICA1-7].	41.38	290	158	4	1	290	1	278	7e-68	224
rs:WP_029583885	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. URHD0069].	43.60	289	157	2	1	289	1	283	7e-68	225
tr:X1JRM8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S21946 {ECO:0000313|EMBL:GAH84070.1}; Flags: Fragment;	44.49	236	131	0	5	240	1	236	7e-68	223
tr:W0VIZ4_ZYGBA	SubName: Full=Probable C-1-tetrahydrofolate synthase,cytoplasmic {ECO:0000313|EMBL:CDH09376.1};	44.44	297	155	4	1	291	1	293	7e-68	238
tr:A0A0D2G1Q8_9EURO	SubName: Full=Unplaced genomic scaffold supercont1.8, whole genome shotgun sequence {ECO:0000313|EMBL:KIW74743.1};	44.18	292	156	3	1	289	1	288	7e-68	238
rs:XP_007863385	FTHFS-domain-containing protein [Gloeophyllum trabeum ATCC 11539].	45.76	295	150	4	3	291	30	320	7e-68	238
tr:M8BKX4_AEGTA	SubName: Full=Bifunctional protein folD 2 {ECO:0000313|EMBL:EMT22458.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:EMT22458};	41.58	303	160	3	2	291	25	323	7e-68	226
tr:K3WR84_PYTUL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:PYU1_T007478};	41.47	299	156	4	3	290	2	292	7e-68	225
rs:WP_028659553	methenyltetrahydrofolate cyclohydrolase [Nocardioides insulae].	40.96	293	162	4	1	293	1	282	7e-68	224
rs:WP_009496087	methenyltetrahydrofolate cyclohydrolase [Weissella ceti].	45.73	293	143	7	3	290	2	283	7e-68	225
rs:WP_027859582	5,10-methylene-tetrahydrofolate cyclohydrolase [Marinobacterium jannaschii].	41.67	288	151	5	1	286	1	273	7e-68	224
sp:FOLD_PELTS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.01	288	156	3	3	290	2	278	7e-68	224
sp:FOLD_PSYA2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.27	291	157	3	2	292	13	292	7e-68	225
tr:A0A059AEM1_EUCGR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KCW52293.1};	39.12	294	173	2	2	293	67	356	7e-68	227
rs:WP_023539221	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces niveus].	42.12	292	159	5	1	292	1	282	7e-68	224
rs:XP_009394801	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X1 [Musa acuminata subsp. malaccensis].	41.98	293	164	2	1	291	84	372	7e-68	227
rs:WP_016373206	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Lactobacillus paracasei].	47.35	264	129	2	28	291	15	268	7e-68	224
tr:A0A067Q3U9_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDQ60820.1};	45.45	297	152	4	2	292	7	299	7e-68	238
tr:A0A0D6Q863_KOMXY	SubName: Full=Bifunctional [5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase] {ECO:0000313|EMBL:GAN99518.1};	44.64	289	154	2	2	290	14	296	7e-68	225
rs:WP_025957245	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB245a_518E10].	41.87	289	161	3	6	293	5	287	7e-68	225
rs:WP_007788176	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium sp. CF122].	44.37	293	155	4	4	292	3	291	8e-68	225
rs:WP_008747579	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. SPB74].	41.55	284	156	5	1	284	1	274	8e-68	224
rs:WP_029607279	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus rhamnosus].	43.60	289	152	3	6	294	5	282	8e-68	224
rs:WP_003586622	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium leguminosarum].	45.49	288	146	6	6	291	12	290	8e-68	225
rs:WP_028739040	methenyltetrahydrofolate cyclohydrolase [Rhizobium selenitireducens].	44.86	292	153	4	5	292	4	291	8e-68	225
rs:WP_036024203	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium yuanmingense].	43.94	289	156	2	1	289	1	283	8e-68	224
rs:WP_038688765	methenyltetrahydrofolate cyclohydrolase [Rhizobium etli].	45.70	291	147	6	3	291	9	290	8e-68	225
rs:WP_046205100	methenyltetrahydrofolate cyclohydrolase [Corynebacterium kroppenstedtii].	43.16	285	149	6	3	286	2	274	9e-68	224
rs:WP_018801002	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora arenicola].	41.44	292	165	4	1	292	1	286	9e-68	224
tr:A0A0A3C6T7_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGQ81304.1};	43.92	296	157	4	1	291	1	292	9e-68	238
tr:A4U339_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.10	290	159	2	2	291	3	286	9e-68	224
rs:WP_030289036	methenyltetrahydrofolate cyclohydrolase [Streptomyces catenulae].	41.44	292	161	5	1	292	1	282	9e-68	224
rs:WP_017946503	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	42.61	284	153	4	1	284	1	274	9e-68	224
rs:WP_021946559	bifunctional protein FolD [Clostridium sp. CAG:967].	43.86	285	144	6	3	286	2	271	9e-68	224
rs:WP_039718370	methenyltetrahydrofolate cyclohydrolase [Scytonema millei].	43.15	292	161	2	1	291	1	288	9e-68	224
rs:WP_024525346	methenyltetrahydrofolate cyclohydrolase [Lactobacillus brevis].	45.42	284	142	5	5	286	4	276	9e-68	224
rs:WP_031073399	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL WC-3742].	42.96	291	155	5	1	291	1	280	9e-68	224
rs:WP_041634587	methenyltetrahydrofolate cyclohydrolase [Magnetospirillum gryphiswaldense].	43.10	290	159	2	2	291	3	286	9e-68	224
rs:XP_012692272	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Clupea harengus].	44.30	298	157	4	1	293	1	294	9e-68	238
tr:E8Z6M3_PFIPI	SubName: Full=Tetrahydrofolate dehydrogenase {ECO:0000313|EMBL:ACU45103.1};	42.96	291	159	2	6	293	9	295	9e-68	225
rs:WP_018797789	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora arenicola].	41.44	292	165	4	1	292	1	286	1e-67	224
rs:WP_040157604	methenyltetrahydrofolate cyclohydrolase [bacterium SIT7].	41.40	285	154	6	1	284	1	273	1e-67	224
sp:FOLD_ACIC1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.15	292	160	4	1	292	1	286	1e-67	224
rs:WP_046432357	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus sp. N54.MGS-719].	44.84	281	143	3	3	283	2	270	1e-67	224
tr:V6F3W9_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.10	290	159	2	2	291	9	292	1e-67	225
tr:J3EE03_9PSED	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.69	287	142	5	6	290	15	292	1e-67	225
rs:WP_031068191	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-118].	40.91	286	159	4	1	286	1	276	1e-67	224
tr:A0A0A4BHX4_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGU21567.1};	43.58	296	158	4	1	291	1	292	1e-67	238
rs:WP_008600338	methylenetetrahydrofolate dehydrogenase [alpha proteobacterium JLT2015].	45.05	293	155	3	1	291	1	289	1e-67	224
rs:WP_047307998	methenyltetrahydrofolate cyclohydrolase [Rhodopseudomonas palustris].	44.98	289	154	2	1	289	1	284	1e-67	224
rs:XP_002153409	C1 tetrahydrofolate synthase, putative [Talaromyces marneffei ATCC 18224].	44.37	293	156	3	1	290	1	289	1e-67	237
tr:R4XAF0_TAPDE	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:CCG82737.1};	44.59	296	157	3	1	293	1	292	1e-67	237
sp:FOLD_RHOP5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.29	289	156	2	1	289	1	284	1e-67	224
rs:WP_043021928	methenyltetrahydrofolate cyclohydrolase [Lactobacillus brevis].	45.42	284	142	5	5	286	4	276	1e-67	224
rs:WP_033308802	methenyltetrahydrofolate cyclohydrolase [Streptomyces iakyrus].	40.41	292	164	4	1	292	1	282	1e-67	224
rs:WP_036743426	methenyltetrahydrofolate cyclohydrolase [Paracoccus halophilus].	43.84	292	157	2	1	292	1	285	1e-67	224
rs:WP_018063475	hypothetical protein [Martelella mediterranea].	45.39	293	152	4	3	291	2	290	1e-67	224
rs:XP_010746877	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Larimichthys crocea].	43.73	295	155	5	3	291	24	313	1e-67	225
rs:WP_015035682	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces venezuelae].	41.61	286	157	4	1	286	1	276	1e-67	224
rs:WP_046664921	methenyltetrahydrofolate cyclohydrolase [Neorhizobium galegae].	45.24	294	153	4	3	292	2	291	1e-67	224
rs:WP_005453450	5,10-methylene-tetrahydrofolate dehydrogenase [Saccharomonospora cyanea].	42.37	295	159	4	1	295	1	284	1e-67	224
rs:XP_009854552	C-1-tetrahydrofolate synthase [Neurospora tetrasperma FGSC 2508].	43.90	287	154	3	3	286	2	284	1e-67	237
rs:WP_027341722	methenyltetrahydrofolate cyclohydrolase [Hamadaea tsunoensis].	41.24	291	165	4	1	291	1	285	1e-67	224
rs:WP_038523156	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus sp. wkB8].	41.38	290	156	4	3	291	2	278	1e-67	224
rs:WP_013709007	methenyltetrahydrofolate cyclohydrolase [Coriobacterium glomerans].	45.74	258	130	3	36	293	34	281	1e-67	224
rs:WP_033064243	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. GM18].	46.69	287	142	5	6	290	12	289	1e-67	224
rs:WP_023030161	MULTISPECIES: FolD protein [Corynebacterium].	42.61	291	156	4	1	291	1	280	1e-67	224
rs:WP_045532730	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. LMB-1].	44.56	294	155	4	3	292	2	291	1e-67	224
tr:W4VVU6_ATTCE	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:ACEP11075-PA};	45.73	293	151	3	3	289	36	326	1e-67	235
rs:WP_009773006	5,10-methylene-tetrahydrofolate dehydrogenase [marine actinobacterium PHSC20C1].	41.41	297	161	6	1	291	1	290	1e-67	224
rs:WP_020082923	5,10-methylene-tetrahydrofolate dehydrogenase [gamma proteobacterium SCGC AAA076-P09].	41.92	291	154	4	1	291	1	276	1e-67	224
rs:WP_007270680	tetrahydrofolate dehydrogenase [Arthrobacter gangotriensis].	40.88	296	165	6	1	292	1	290	1e-67	224
rs:WP_014363927	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia canadensis].	41.03	290	160	3	4	292	3	282	1e-67	224
rs:WP_042934611	methenyltetrahydrofolate cyclohydrolase [Pseudomonas gingeri].	46.29	283	144	3	6	288	11	285	1e-67	224
tr:B2DEU9_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.64	287	147	5	3	288	9	287	1e-67	224
rs:WP_045451733	5,10-methylene-tetrahydrofolate cyclohydrolase [Psychrobacter sp. JCM 18903].	41.92	291	158	3	2	292	7	286	1e-67	224
rs:XP_712674	likely C1-tetrahydrofolate synthase [Candida albicans SC5314].	43.58	296	158	4	1	291	1	292	1e-67	237
rs:WP_038971508	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. CCBAU 15635].	43.64	291	157	3	1	290	1	285	1e-67	224
rs:WP_009338489	5,10-methylene-tetrahydrofolate dehydrogenase [Afipia sp. 1NLS2].	42.91	289	159	2	1	289	1	283	1e-67	224
tr:H5SK41_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.07	271	145	4	15	284	7	266	1e-67	224
rs:WP_027624673	methenyltetrahydrofolate cyclohydrolase [Clostridium lundense].	42.14	280	151	3	6	285	5	273	1e-67	224
rs:XP_002422211	C-1-tetrahydrofolate synthase, mitochondrial precursor, putative [Candida dubliniensis CD36].	42.91	296	160	4	1	291	1	292	1e-67	237
rs:WP_038947858	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. CCBAU 15544].	43.64	291	157	3	1	290	1	285	1e-67	224
rs:WP_030586351	methenyltetrahydrofolate cyclohydrolase [Streptomyces rimosus].	41.44	292	161	5	1	292	1	282	1e-67	224
rs:WP_026534314	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. H14].	42.86	294	159	6	1	290	1	289	1e-67	224
rs:WP_014087719	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudogulbenkiania sp. NH8B].	48.63	292	135	8	5	292	14	294	1e-67	224
rs:WP_032121673	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. LF2].	40.41	292	163	2	3	294	2	282	1e-67	224
rs:WP_012359673	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium urealyticum].	43.45	290	153	4	1	290	4	282	1e-67	224
tr:C4YMB9_CANAW	SubName: Full=C-1-tetrahydrofolate synthase, mitochondrial {ECO:0000313|EMBL:EEQ43750.1};	43.58	296	158	4	1	291	1	292	1e-67	237
rs:WP_036038805	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium yuanmingense].	43.94	289	156	2	1	289	1	283	1e-67	224
tr:V9QW66_9PSED	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.32	285	145	3	6	290	16	292	1e-67	224
rs:WP_016908858	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces xiaopingdaonensis].	41.78	292	160	5	1	292	1	282	1e-67	224
rs:WP_037505317	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. DC-6].	47.75	289	144	3	2	290	13	294	1e-67	224
rs:WP_025362441	5,10-methylene-tetrahydrofolate cyclohydrolase [Synechococcus sp. WH 8109].	45.23	283	145	3	6	288	5	277	1e-67	224
rs:WP_024511182	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. ARR65].	44.29	289	155	2	1	289	1	283	1e-67	224
rs:WP_045581501	methenyltetrahydrofolate cyclohydrolase [Azospirillum thiophilum].	46.53	288	143	6	3	286	4	284	1e-67	225
rs:WP_008393779	MULTISPECIES: tetrahydrofolate dehydrogenase [Leptospira].	39.66	295	164	2	1	295	1	281	1e-67	224
rs:WP_027981969	methenyltetrahydrofolate cyclohydrolase [gamma proteobacterium L18].	44.79	288	148	3	2	289	3	279	1e-67	224
rs:XP_007574778	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Poecilia formosa].	43.39	295	156	6	3	291	24	313	1e-67	225
tr:A0A0C2IP02_9PEZI	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:KIH86807.1};	43.49	292	158	3	1	289	1	288	2e-67	237
rs:WP_028139304	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium].	43.60	289	157	2	1	289	1	283	2e-67	224
rs:WP_013130919	5,10-methylene-tetrahydrofolate dehydrogenase [Thermobispora bispora].	43.34	293	151	6	1	291	1	280	2e-67	224
tr:K2MTX4_TRYCR	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic, putative {ECO:0000313|EMBL:EKF38693.1};	41.36	295	165	3	3	293	98	388	2e-67	227
rs:WP_035112048	methenyltetrahydrofolate cyclohydrolase [Corynebacterium freiburgense].	43.73	295	147	6	1	291	4	283	2e-67	224
tr:K3WQ13_PYTUL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:PYU1_T007055};	39.34	305	168	3	2	293	4	304	2e-67	224
rs:WP_031096562	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-15].	41.61	286	157	5	1	286	1	276	2e-67	224
tr:F5XPG5_MICPN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.33	282	146	5	5	286	16	286	2e-67	224
gp:HB883549_1	Sequence 16224 from Patent EP2096177. [Neurospora crassa]	43.90	287	154	3	3	286	2	284	2e-67	237
sp:FOLD1_ACIAD	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.70	291	147	6	2	290	10	291	2e-67	224
sp:FOLD_KOCRD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.93	298	170	6	1	294	1	293	2e-67	224
rs:WP_007756836	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium sp. CF080].	44.52	292	154	4	5	292	4	291	2e-67	224
rs:WP_008963905	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobium sp. STM 3809].	46.02	289	150	2	1	289	1	283	2e-67	224
tr:C0WIS5_9CORY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.61	291	156	4	1	291	4	283	2e-67	223
tr:A0A0A3BUN3_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGQ83757.1};	44.01	309	152	5	1	292	22	326	2e-67	237
rs:WP_035444000	methenyltetrahydrofolate cyclohydrolase, partial [Asaia platycodi].	43.99	291	157	2	1	291	7	291	2e-67	224
tr:C4YNB3_CANAW	SubName: Full=C-1-tetrahydrofolate synthase, mitochondrial {ECO:0000313|EMBL:EEQ43146.1};	44.37	302	151	4	1	289	65	362	2e-67	237
rs:WP_013438201	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus].	44.84	281	143	3	3	283	2	270	2e-67	223
tr:A0A0A3CWW7_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGR01498.1};	44.01	309	152	5	1	292	22	326	2e-67	237
tr:A0A0A3BT82_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGQ82625.1};	44.37	302	151	4	1	289	65	362	2e-67	237
tr:W2WFQ0_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETP08409.1};	42.09	297	153	4	4	289	3	291	2e-67	224
tr:A0A0A3WYH4_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGT64591.1};	44.01	309	152	5	1	292	66	370	2e-67	237
rs:XP_718690	hypothetical protein CaO19.7534 [Candida albicans SC5314].	44.01	309	152	5	1	292	66	370	2e-67	237
rs:WP_041161150	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. TKP].	46.32	285	145	3	6	290	15	291	2e-67	224
rs:XP_008895352	hypothetical protein PPTG_04804 [Phytophthora parasitica INRA-310].	42.09	297	153	4	4	289	3	291	2e-67	224
rs:WP_010315984	5,10-methylene-tetrahydrofolate dehydrogenase [Saccharopolyspora spinosa].	41.64	293	160	5	1	293	1	282	2e-67	223
rs:WP_044537453	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. LTSP885].	44.21	285	149	3	1	285	1	275	2e-67	223
tr:A0A0A6J5W5_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KHC44787.1};	44.01	309	152	5	1	292	22	326	2e-67	237
rs:WP_046611732	methenyltetrahydrofolate cyclohydrolase [Neorhizobium galegae].	45.58	294	152	4	3	292	2	291	2e-67	224
rs:WP_023768071	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. LNHC232B00].	44.52	292	154	4	2	292	6	290	2e-67	224
tr:A0A0A6MXZ4_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KHC61050.1};	44.01	309	152	5	1	292	22	326	2e-67	237
rs:WP_040760471	methenyltetrahydrofolate cyclohydrolase [Weissella paramesenteroides].	45.05	293	145	6	3	290	2	283	2e-67	224
tr:A0A0A6I4E3_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KHC30943.1};	44.01	309	152	5	1	292	22	326	2e-67	237
rs:WP_037681953	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Streptomyces griseus].	44.48	290	150	3	1	290	1	279	2e-67	223
tr:A0A0A4CNR5_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGU23619.1};	44.01	309	152	5	1	292	22	326	2e-67	237
rs:WP_033571424	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus rhamnosus].	43.60	289	152	3	6	294	5	282	2e-67	223
tr:A0A0A4AZW7_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGU03099.1};	44.37	302	151	4	1	289	65	362	2e-67	237
tr:A0A0A6HWP0_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KHC29397.1};	44.01	309	152	5	1	292	66	370	2e-67	237
rs:WP_021813549	methylenetetrahydrofolate dehydrogenase [Psychrobacter aquaticus].	42.27	291	155	5	3	292	11	289	2e-67	224
tr:A0A0B2QXP6_GLYSO	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:KHN26446.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KHN26446.1}; EC=3.5.4.9 {ECO:0000313|EMBL:KHN26446.1}; Flags: Fragment;	42.11	285	158	3	11	293	1	280	2e-67	223
tr:A0A0A4BCZ7_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGU19897.1};	44.01	309	152	5	1	292	22	326	2e-67	237
rs:WP_033394218	methenyltetrahydrofolate cyclohydrolase [Kibdelosporangium aridum].	41.72	290	158	5	1	290	1	279	2e-67	223
rs:WP_036314580	methenyltetrahydrofolate cyclohydrolase [Micrococcus luteus].	40.80	299	161	7	1	292	1	290	2e-67	224
rs:WP_036750358	methenyltetrahydrofolate cyclohydrolase [Peptococcaceae bacterium SCADC1_2_3].	42.86	287	152	4	4	290	3	277	2e-67	223
rs:WP_028133370	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium japonicum].	43.60	289	157	2	1	289	1	283	2e-67	224
tr:A0A0A3ZV26_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGU01860.1};	44.01	309	152	5	1	292	22	326	2e-67	237
tr:X0ZVE2_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_L00598 {ECO:0000313|EMBL:GAG61907.1};	41.16	294	158	5	3	293	2	283	2e-67	223
rs:WP_037276371	methenyltetrahydrofolate cyclohydrolase [Roseovarius mucosus].	45.58	294	149	3	1	292	1	285	2e-67	224
rs:WP_024899871	methenyltetrahydrofolate cyclohydrolase [Ochrobactrum rhizosphaerae].	42.21	289	160	2	1	289	1	282	2e-67	224
sp:FOLD_PHEZH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.07	295	157	2	1	291	1	291	2e-67	224
tr:C5R8B8_WEIPA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.05	293	145	6	3	290	9	290	2e-67	224
tr:W0GVP0_9SYNE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.23	283	145	3	6	288	14	286	2e-67	224
rs:WP_035863390	methenyltetrahydrofolate cyclohydrolase [Kitasatospora cheerisanensis].	42.61	291	156	5	1	291	1	280	2e-67	223
rs:WP_023943953	methenyltetrahydrofolate cyclohydrolase [Gluconobacter frateurii].	43.84	292	158	2	1	292	8	293	2e-67	224
tr:A0A0A6HXQ0_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KHC29822.1};	44.01	309	152	5	1	292	66	370	2e-67	237
rs:WP_030998247	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5630].	41.20	284	157	5	1	284	1	274	2e-67	223
sp:FOLD_MICLC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.27	298	164	6	1	292	1	290	2e-67	224
rs:WP_011055876	methenyltetrahydrofolate cyclohydrolase [Thermosynechococcus elongatus].	48.67	263	129	2	26	288	4	260	2e-67	223
tr:F0XCY1_GROCL	SubName: Full=C1 tetrahydrofolate ligase {ECO:0000313|EMBL:EFX04398.1};	43.49	292	158	3	1	289	1	288	2e-67	236
rs:XP_005970475	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Pantholops hodgsonii].	44.75	295	122	7	1	292	1	257	2e-67	222
rs:WP_029477870	methenyltetrahydrofolate cyclohydrolase [Deinococcus frigens].	48.08	260	128	4	34	293	30	282	2e-67	223
tr:A0A0A6KZP5_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KHC66992.1};	44.37	302	151	4	1	289	22	319	2e-67	236
rs:WP_041985411	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. AcH 505].	40.96	293	163	5	1	293	1	283	2e-67	223
tr:A0A0A6MC94_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KHC54105.1};	44.01	309	152	5	1	292	66	370	2e-67	237
rs:WP_024706030	methenyltetrahydrofolate cyclohydrolase [Martelella sp. AD-3].	45.08	295	154	4	3	293	2	292	2e-67	224
rs:WP_046316159	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus mellifer].	42.27	291	157	3	1	291	1	280	2e-67	223
rs:WP_030969017	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-1824].	41.61	286	157	5	1	286	1	276	2e-67	223
rs:WP_012557576	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium leguminosarum].	45.49	288	146	6	6	291	12	290	2e-67	224
rs:XP_008841749	PREDICTED: LOW QUALITY PROTEIN: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Nannospalax galili].	44.07	295	158	3	6	294	162	455	2e-67	228
tr:U7Q7I6_SPOS1	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERT02985.1};	43.49	292	158	3	1	289	1	288	2e-67	236
rs:WP_035227830	methenyltetrahydrofolate cyclohydrolase, partial [Acidiphilium angustum].	46.05	291	143	3	1	291	1	277	2e-67	223
tr:J9ISQ0_9SPIT	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:EJY82689.1};	42.86	266	144	3	25	286	9	270	2e-67	223
tr:A0A0A3BPM9_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGQ81360.1};	44.37	302	151	4	1	289	66	363	2e-67	237
rs:WP_045693527	methenyltetrahydrofolate cyclohydrolase [Streptomyces rubellomurinus].	42.61	291	156	5	1	291	1	280	2e-67	223
rs:WP_040922080	methenyltetrahydrofolate cyclohydrolase [Saccharomonospora xinjiangensis].	41.69	295	161	4	1	295	1	284	2e-67	223
rs:XP_011394878	C-1-tetrahydrofolate synthase [Neurospora crassa OR74A].	43.90	287	154	3	3	286	194	476	2e-67	238
tr:M3INV3_CANMX	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:EMG48081.1};	42.57	296	161	4	1	291	1	292	3e-67	236
tr:A0A085E1G5_MICLU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.27	298	164	6	1	292	1	290	3e-67	224
rs:WP_035774613	methenyltetrahydrofolate cyclohydrolase [Asaia astilbis].	43.05	295	162	2	1	295	14	302	3e-67	224
rs:WP_034574306	methenyltetrahydrofolate cyclohydrolase [Mageeibacillus indolicus].	45.14	288	144	4	1	285	1	277	3e-67	223
tr:A0A060QCN8_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.99	291	157	2	1	291	7	291	3e-67	224
rs:WP_021596501	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomadura madurae].	41.78	292	159	4	1	292	1	281	3e-67	223
rs:WP_028142992	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium].	43.64	291	157	3	1	290	1	285	3e-67	224
rs:WP_033253207	methenyltetrahydrofolate cyclohydrolase [Kitasatospora phosalacinea].	42.27	291	157	5	1	291	1	280	3e-67	223
rs:WP_040338482	methenyltetrahydrofolate cyclohydrolase [Candidatus Blastococcus massiliensis].	42.16	287	155	4	1	287	1	276	3e-67	223
rs:WP_023020649	MULTISPECIES: FolD protein [Corynebacterium].	42.61	291	156	4	1	291	1	280	3e-67	223
rs:XP_012358135	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Nomascus leucogenys].	47.19	267	134	3	3	263	37	302	3e-67	224
rs:XP_005095912	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Aplysia californica].	45.61	296	150	5	3	292	2	292	3e-67	236
tr:A0A0D2GC87_9EURO	SubName: Full=Capronia semiimmersa strain CBS 27337 unplaced genomic scaffold supercont1.3, whole genome shotgun sequence {ECO:0000313|EMBL:KIW69714.1};	43.49	292	158	3	1	289	116	403	3e-67	237
rs:WP_045811258	methenyltetrahydrofolate cyclohydrolase [Brevundimonas sp. KM4].	43.69	293	157	2	3	291	8	296	3e-67	224
rs:WP_040930854	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Paenibacillus larvae].	52.56	215	92	2	81	295	2	206	3e-67	220
rs:WP_035579925	methenyltetrahydrofolate cyclohydrolase [Hyphomonas jannaschiana].	45.89	292	146	5	1	289	1	283	3e-67	223
rs:WP_046327277	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus helsingborgensis].	40.48	289	160	3	3	291	2	278	3e-67	223
sp:FOLD_RHOPA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.98	289	154	2	1	289	1	284	3e-67	223
rs:WP_006347125	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces tsukubaensis].	41.10	292	162	5	1	292	1	282	3e-67	223
rs:WP_046631539	methenyltetrahydrofolate cyclohydrolase [Neorhizobium galegae].	45.24	294	153	4	3	292	2	291	3e-67	223
rs:WP_029081695	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. th.b2].	44.06	286	150	3	1	286	1	276	3e-67	223
tr:A0A021VS76_9CELL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.20	294	158	6	3	292	43	331	3e-67	224
rs:WP_038950929	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium].	43.60	289	157	2	1	289	1	283	3e-67	223
rs:WP_029530083	methenyltetrahydrofolate cyclohydrolase [Pseudomonas fuscovaginae].	44.56	285	146	4	2	286	3	275	3e-67	223
rs:WP_020508918	methenyltetrahydrofolate cyclohydrolase [Actinoplanes globisporus].	45.07	284	141	3	6	289	5	273	3e-67	223
rs:WP_026196979	methenyltetrahydrofolate cyclohydrolase [Sciscionella marina].	41.92	291	158	5	1	291	1	280	3e-67	223
rs:WP_022939186	hypothetical protein [Dielma fastidiosa].	41.38	290	160	3	1	290	1	280	3e-67	223
rs:XP_007373715	hypothetical protein SPAPADRAFT_134523 [Spathaspora passalidarum NRRL Y-27907].	41.89	296	163	4	1	291	1	292	3e-67	236
rs:WP_009717125	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces himastatinicus].	42.31	286	155	5	1	286	1	276	3e-67	223
tr:A0A0A6HVK4_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KHC28704.1};	43.58	296	158	4	1	291	1	292	3e-67	236
rs:WP_020624736	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudonocardia sp. P2].	40.80	299	161	7	1	292	1	290	3e-67	223
tr:A0A099P6W0_ISSOR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGK39942.1};	43.24	296	161	3	1	293	34	325	3e-67	236
rs:WP_041630145	methenyltetrahydrofolate cyclohydrolase [Corynebacterium variabile].	42.96	291	155	4	1	291	1	280	3e-67	223
rs:XP_005949676	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Haplochromis burtoni].	43.73	295	155	5	3	291	24	313	3e-67	224
sp:FOLD_RHOPS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.64	289	155	2	1	289	1	284	3e-67	223
rs:WP_020392433	5,10-methylene-tetrahydrofolate dehydrogenase [Kribbella catacumbae].	41.96	286	156	4	1	286	1	276	3e-67	223
rs:WP_045812417	5,10-methylene-tetrahydrofolate cyclohydrolase [Rickettsia hoogstraalii].	38.34	326	155	4	4	293	3	318	3e-67	224
rs:WP_026415531	methenyltetrahydrofolate cyclohydrolase [Actinomadura oligospora].	41.44	292	160	4	1	292	1	281	4e-67	223
rs:WP_038553793	5,10-methylene-tetrahydrofolate cyclohydrolase [Synechococcus sp. KORDI-52].	45.58	283	144	3	6	288	5	277	4e-67	223
rs:XP_002616752	hypothetical protein CLUG_03993 [Clavispora lusitaniae ATCC 42720].	42.12	311	157	4	1	292	64	370	4e-67	236
rs:WP_034337852	methenyltetrahydrofolate cyclohydrolase [Deinococcus misasensis].	43.40	288	145	5	6	292	4	274	4e-67	222
rs:WP_030218217	methenyltetrahydrofolate cyclohydrolase [Streptomyces bikiniensis].	41.96	286	156	4	1	286	1	276	4e-67	223
tr:A0A023F3R2_TRIIF	SubName: Full=Putative methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:JAC16045.1}; Flags: Fragment;	41.50	294	164	4	4	293	1	290	4e-67	224
rs:WP_046505326	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL B-24891].	41.61	286	157	5	1	286	1	276	4e-67	223
rs:XP_010926053	PREDICTED: bifunctional protein FolD 1, mitochondrial [Elaeis guineensis].	41.72	290	163	2	5	292	81	366	4e-67	225
rs:WP_019231256	hypothetical protein [Rickettsiaceae bacterium Os18].	43.34	293	155	5	3	291	2	287	4e-67	223
rs:WP_026973854	5,10-methylene-tetrahydrofolate cyclohydrolase [Alicyclobacillus contaminans].	45.07	284	144	3	3	286	2	273	4e-67	223
tr:V5G8G9_BYSSN	SubName: Full=C1 tetrahydrofolate synthase {ECO:0000313|EMBL:GAD97182.1};	44.71	293	155	3	1	290	1	289	4e-67	236
rs:WP_025650594	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Psychrobacter].	41.58	291	159	3	2	292	10	289	4e-67	223
rs:WP_035464261	methenyltetrahydrofolate cyclohydrolase [Lactobacillus brevis].	45.42	284	142	5	5	286	4	276	4e-67	223
rs:WP_041791441	methenyltetrahydrofolate cyclohydrolase [Microlunatus phosphovorus].	44.48	281	145	5	6	286	1	270	4e-67	223
sp:FOLD_PSYCK	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.58	291	159	3	2	292	13	292	4e-67	223
tr:A0A078DNW1_BRANA	SubName: Full=BnaA03g25950D protein {ECO:0000313|EMBL:CDX90915.1};	43.40	288	121	4	6	291	60	307	4e-67	223
rs:WP_037297817	methenyltetrahydrofolate cyclohydrolase [Roseovarius sp. TM1035].	45.24	294	150	3	1	292	1	285	4e-67	223
rs:XP_005453396	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like isoform X2 [Oreochromis niloticus].	45.27	296	153	4	1	291	1	292	4e-67	236
rs:WP_022195886	bifunctional protein FolD [Azospirillum sp. CAG:239].	45.76	295	141	6	1	291	1	280	4e-67	223
rs:WP_038548046	5,10-methylene-tetrahydrofolate cyclohydrolase [Synechococcus sp. KORDI-100].	44.88	283	146	3	6	288	5	277	4e-67	223
rs:WP_027699395	methenyltetrahydrofolate cyclohydrolase [Weissella oryzae].	42.71	288	150	5	3	286	2	278	4e-67	223
rs:WP_046769324	methenyltetrahydrofolate cyclohydrolase [Jiangella alkaliphila].	42.71	295	159	5	1	293	1	287	4e-67	223
tr:A0A0A0NM00_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.61	291	157	5	1	291	1	281	4e-67	223
tr:K1T9Y5_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKC64329.1}; Flags: Fragment;	54.46	213	87	2	78	290	1	203	4e-67	220
rs:WP_044573867	methenyltetrahydrofolate cyclohydrolase [Streptomyces iranensis].	42.61	291	157	5	1	291	1	281	4e-67	223
rs:WP_018561224	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. BoleA5].	41.03	290	161	5	1	290	1	280	4e-67	223
rs:WP_007281680	5,10-methylene-tetrahydrofolate dehydrogenase [Gluconobacter thailandicus].	43.49	292	159	2	1	292	8	293	4e-67	223
sp:FOLD_LACBA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.07	284	143	5	5	286	4	276	4e-67	223
tr:A6E0Q2_9RHOB	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.24	294	150	3	1	292	6	290	4e-67	223
rs:WP_011907032	5,10-methylene-tetrahydrofolate dehydrogenase [Novosphingobium aromaticivorans].	47.57	288	144	3	3	290	2	282	4e-67	223
sp:FOLD_ROSCS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.76	290	156	2	1	290	1	280	4e-67	223
tr:A0A090MRY2_AFIFE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.91	289	159	2	1	289	1	283	4e-67	223
rs:WP_028165192	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium elkanii].	43.60	289	157	2	1	289	1	283	4e-67	223
rs:WP_031468209	methenyltetrahydrofolate cyclohydrolase [Sciscionella sp. SE31].	41.58	291	159	5	1	291	1	280	4e-67	223
rs:WP_021871776	bifunctional protein FolD [Clostridium sp. CAG:1193].	42.50	280	146	3	5	284	3	267	4e-67	222
rs:XP_010032808	PREDICTED: bifunctional protein FolD 2-like isoform X3 [Eucalyptus grandis].	39.12	294	173	2	2	293	135	424	4e-67	227
sp:FOLD_RICCK	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.69	290	161	3	4	292	3	282	4e-67	223
rs:XP_003447800	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like isoform X1 [Oreochromis niloticus].	44.97	298	155	4	1	293	1	294	5e-67	236
rs:WP_003715770	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus oris].	43.86	285	145	6	5	286	3	275	5e-67	223
tr:G2NIM5_STREK	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.90	284	155	5	1	284	4	277	5e-67	223
rs:WP_040255595	5,10-methylene-tetrahydrofolate cyclohydrolase [Rickettsia hoogstraalii].	38.34	326	155	4	4	293	3	318	5e-67	224
rs:WP_032960072	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus rhamnosus].	43.25	289	153	3	6	294	5	282	5e-67	222
tr:K7FNY7_PELSI	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPSIP00000009747}; Flags: Fragment;	53.30	227	99	3	74	294	34	259	5e-67	221
tr:F7W6E3_SORMK	SubName: Full=WGS project CABT00000000 data, contig 2.34 {ECO:0000313|EMBL:CCC13082.1};	43.25	289	157	3	3	288	211	495	5e-67	237
rs:WP_023721594	5,10-methylene-tetrahydrofolate dehydrogenase [Mesorhizobium sp. LSHC420B00].	42.27	291	160	3	3	293	8	290	5e-67	223
rs:WP_037251531	methenyltetrahydrofolate cyclohydrolase [Rhodococcus rhodnii].	41.38	290	159	5	1	290	1	279	5e-67	222
rs:WP_013177617	5,10-methylene-tetrahydrofolate dehydrogenase [Truepera radiovictrix].	43.64	291	148	4	1	291	1	275	5e-67	222
tr:A0A075HC29_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.86	294	154	4	1	292	1	282	5e-67	223
rs:WP_019039580	hypothetical protein [Psychroflexus tropicus].	42.18	294	156	4	4	290	2	288	5e-67	223
rs:WP_021106020	bifunctional protein FolD [Propionibacterium granulosum].	41.92	291	159	4	1	291	1	281	5e-67	222
rs:WP_044412828	methenyltetrahydrofolate cyclohydrolase [Rhodopseudomonas palustris].	43.60	289	158	2	1	289	1	284	5e-67	223
rs:WP_030180002	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-813].	40.41	292	164	4	1	292	1	282	5e-67	222
rs:WP_028348405	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium elkanii].	44.29	289	155	2	1	289	1	283	5e-67	223
tr:A0A0D6PSG7_9PROT	SubName: Full=Bifunctional [5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase] {ECO:0000313|EMBL:GAN90298.1};	43.49	292	159	2	1	292	8	293	5e-67	223
rs:WP_045444835	5,10-methylene-tetrahydrofolate cyclohydrolase [Psychrobacter sp. JCM 18902].	41.92	291	158	3	2	292	7	286	5e-67	223
rs:WP_046926406	methenyltetrahydrofolate cyclohydrolase [Streptomyces lydicus].	41.10	292	162	5	1	292	1	282	5e-67	222
tr:A0A0B2SDX5_GLYSO	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:KHN44951.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KHN44951.1}; EC=3.5.4.9 {ECO:0000313|EMBL:KHN44951.1};	41.16	294	164	3	2	293	63	349	5e-67	224
rs:WP_003657985	5,10-methylene-tetrahydrofolate dehydrogenase [Moraxella catarrhalis].	41.72	290	156	5	3	291	2	279	5e-67	222
rs:WP_002856601	5,10-methylene-tetrahydrofolate dehydrogenase [Micrococcus luteus].	40.27	298	164	6	1	292	1	290	5e-67	223
rs:WP_028158630	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium japonicum].	43.25	289	158	2	1	289	1	283	5e-67	223
rs:WP_030528734	methenyltetrahydrofolate cyclohydrolase [Phycicoccus jejuensis].	41.44	292	164	5	1	292	1	285	6e-67	223
gp:CP000409_585	Methylenetetrahydrofolate dehydrogenase [Rickettsia canadensis str. McKiel]	40.69	290	161	3	4	292	8	287	6e-67	223
rs:WP_010189789	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Nitrosoarchaeum limnia].	42.86	294	154	4	1	292	1	282	6e-67	222
rs:WP_018896645	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium sp. 2MFCol3.1].	43.43	297	158	5	1	292	1	292	6e-67	223
rs:WP_017489281	5,10-methylene-tetrahydrofolate dehydrogenase [Micrococcus luteus].	41.64	293	155	7	1	286	1	284	6e-67	223
rs:WP_019993558	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	41.90	284	155	5	1	284	1	274	6e-67	222
tr:A0A0D2ASM7_9PEZI	SubName: Full=Verruconis gallopava strain CBS 43764 unplaced genomic scaffold supercont1.22, whole genome shotgun sequence {ECO:0000313|EMBL:KIW02169.1};	43.55	287	155	3	3	286	63	345	6e-67	236
tr:M7X4L7_RHOT1	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:EMS25261.1};	43.62	298	155	5	3	291	70	363	6e-67	236
tr:A0A0A2VSV6_BEABA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KGQ09215.1};	45.02	291	146	4	1	288	149	428	6e-67	236
rs:WP_015073128	5,10-methylene-tetrahydrofolate dehydrogenase [Gluconobacter oxydans].	43.49	292	159	2	1	292	8	293	6e-67	223
rs:WP_020029679	5,10-methylene-tetrahydrofolate dehydrogenase [gamma proteobacterium SCGC AAA076-P13].	41.24	291	156	4	1	291	1	276	6e-67	222
rs:WP_015828733	5,10-methylene-tetrahydrofolate dehydrogenase [Hirschia baltica].	44.60	287	147	5	6	289	5	282	6e-67	223
rs:WP_042520407	methenyltetrahydrofolate cyclohydrolase [Lactobacillus brevis].	45.07	284	143	5	5	286	4	276	6e-67	222
rs:WP_045656082	methenyltetrahydrofolate cyclohydrolase [Hyphomonadaceae bacterium BRH_c29].	49.03	259	124	4	34	289	30	283	6e-67	223
rs:XP_002498490	ZYRO0G11550p [Zygosaccharomyces rouxii].	44.11	297	156	4	1	291	1	293	6e-67	235
rs:WP_018847413	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. CNT372].	41.96	286	156	5	1	286	1	276	6e-67	222
rs:WP_001070305	bifunctional protein FolD [Leptospira interrogans].	39.32	295	165	2	1	295	1	281	6e-67	222
tr:G3NTC1_GASAC	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGACP00000008589}; Flags: Fragment;	45.30	298	154	4	1	293	2	295	6e-67	235
rs:WP_014154498	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	41.26	286	158	5	1	286	1	276	6e-67	222
rs:WP_019431550	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. AA0539].	41.44	292	161	5	1	292	1	282	6e-67	222
rs:XP_008024394	hypothetical protein SETTUDRAFT_47098 [Setosphaeria turcica Et28A].	43.84	292	157	3	1	289	1	288	6e-67	235
rs:WP_026402621	methenyltetrahydrofolate cyclohydrolase [Actinomadura rifamycini].	42.66	293	157	4	1	293	1	282	6e-67	222
tr:S3D473_OPHP1	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:EPE08175.1};	44.52	292	155	3	1	289	164	451	7e-67	236
rs:WP_024583160	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium].	44.29	289	155	2	1	289	1	283	7e-67	222
rs:WP_002717924	FolD protein [Afipia felis].	42.56	289	160	2	1	289	1	283	7e-67	222
rs:WP_037199061	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. OK494].	44.18	292	155	4	5	292	1	288	7e-67	222
tr:F3S542_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.94	289	156	2	2	290	15	297	7e-67	223
rs:WP_004479792	tetrahydrofolate dehydrogenase [Leptospira santarosai].	39.66	295	164	2	1	295	1	281	7e-67	222
rs:WP_034927234	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Acetobacteraceae].	43.94	289	156	2	2	290	14	296	7e-67	223
rs:WP_010623678	tetrahydrofolate dehydrogenase [Lactobacillus versmoldensis].	44.06	286	149	4	5	290	3	277	7e-67	222
tr:B8ENP0_METSB	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.11	297	151	5	3	291	21	310	7e-67	223
rs:XP_003673668	hypothetical protein NCAS_0A07290 [Naumovozyma castellii CBS 4309].	42.47	299	162	4	1	293	1	295	7e-67	235
tr:A5DD97_PICGU	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EDK37150.2};	44.15	299	151	4	3	289	35	329	7e-67	235
rs:WP_005326797	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium tuberculostearicum].	42.27	291	157	4	1	291	1	280	7e-67	222
rs:WP_041368858	methenyltetrahydrofolate cyclohydrolase [Methylocella silvestris].	44.11	297	151	5	3	291	8	297	7e-67	223
rs:WP_035009786	methenyltetrahydrofolate cyclohydrolase [Corynebacterium jeikeium].	43.64	291	154	5	1	291	4	284	7e-67	222
rs:WP_026874826	methenyltetrahydrofolate cyclohydrolase [Jiangella gansuensis].	42.81	292	161	4	1	292	1	286	7e-67	222
rs:XP_001485577	hypothetical protein PGUG_01248 [Meyerozyma guilliermondii ATCC 6260].	44.15	299	151	4	3	289	35	329	7e-67	235
rs:WP_047166040	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. Y57].	47.57	288	144	3	3	290	14	294	8e-67	222
rs:WP_002630814	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira weilii].	38.64	295	167	2	1	295	1	281	8e-67	222
sp:FOLD_DINSH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.49	292	161	1	1	292	1	288	8e-67	222
rs:WP_042331932	methenyltetrahydrofolate cyclohydrolase [Desulfosporosinus orientis].	39.44	284	160	3	3	286	2	273	8e-67	222
rs:WP_008604379	5,10-methylene-tetrahydrofolate dehydrogenase [Thermoplasmatales archaeon SCGC AB-540-F20].	38.91	293	168	3	1	293	1	282	8e-67	222
rs:WP_019548704	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sulphureus].	41.44	292	161	5	1	292	1	282	8e-67	222
tr:A0A0A3ZPG5_CANAX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGU00933.1};	43.58	296	158	4	1	291	1	292	8e-67	235
rs:WP_005291742	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium jeikeium].	43.64	291	154	5	1	291	4	284	8e-67	222
rs:WP_018252355	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora pacifica].	41.10	292	166	4	1	292	1	286	8e-67	222
rs:XP_011490026	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Oryzias latipes].	43.05	295	157	5	3	291	24	313	8e-67	223
rs:XP_001557201	hypothetical protein BC1G_04451 [Botrytis cinerea B05.10].	42.12	292	162	3	1	289	1	288	9e-67	235
rs:WP_029433371	methenyltetrahydrofolate cyclohydrolase [Blastococcus sp. URHD0036].	42.12	292	158	4	1	292	1	281	9e-67	222
rs:WP_037185787	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. YR519].	45.55	292	151	4	5	292	4	291	9e-67	223
rs:WP_004502541	MULTISPECIES: tetrahydrofolate dehydrogenase [Leptospira].	38.64	295	167	2	1	295	1	281	9e-67	222
rs:XP_004668280	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Jaculus jaculus].	51.87	241	109	3	61	295	148	387	9e-67	225
rs:WP_002970862	tetrahydrofolate dehydrogenase [Leptospira interrogans].	38.98	295	166	2	1	295	1	281	9e-67	222
rs:WP_043914441	methenyltetrahydrofolate cyclohydrolase [Kitasatospora griseola].	42.27	291	157	5	1	291	1	280	9e-67	222
rs:WP_036556581	methenyltetrahydrofolate cyclohydrolase [Oceanicola sp. MCTG156(1a)].	43.69	293	160	2	1	292	1	289	9e-67	222
rs:XP_001527533	C-1-tetrahydrofolate synthase, mitochondrial precursor [Lodderomyces elongisporus NRRL YB-4239].	45.70	302	147	3	1	289	29	326	9e-67	235
rs:WP_043149336	methenyltetrahydrofolate cyclohydrolase [Sphingobium sp. Ant17].	44.48	290	154	3	3	292	2	284	9e-67	222
rs:WP_014565972	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus amylovorus].	44.48	281	144	3	3	283	2	270	9e-67	221
rs:WP_040424870	methenyltetrahydrofolate cyclohydrolase [Corynebacterium pseudogenitalium].	41.92	291	158	4	1	291	1	280	9e-67	221
rs:WP_002755070	tetrahydrofolate dehydrogenase [Leptospira borgpetersenii].	38.98	295	166	2	1	295	1	281	9e-67	221
rs:WP_043012516	methenyltetrahydrofolate cyclohydrolase [Corynebacterium jeikeium].	44.41	295	146	7	1	291	1	281	9e-67	221
rs:WP_013107976	5,10-methylene-tetrahydrofolate dehydrogenase [Moraxella catarrhalis].	41.72	290	156	5	3	291	2	279	9e-67	221
rs:WP_035203132	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus clausii].	40.48	289	157	4	5	293	2	275	9e-67	221
rs:WP_017506289	5,10-methylene-tetrahydrofolate dehydrogenase [alpha proteobacterium L41A].	43.00	293	159	3	3	291	8	296	9e-67	222
tr:A0A0B3A561_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.40	288	142	7	1	288	4	270	1e-66	221
rs:WP_029087643	methenyltetrahydrofolate cyclohydrolase [Brevundimonas aveniformis].	41.64	293	163	2	3	291	4	292	1e-66	222
tr:X0YZU1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_C03829 {ECO:0000313|EMBL:GAG62150.1}; Flags: Fragment;	41.73	266	138	2	3	255	5	266	1e-66	221
rs:WP_003444198	5,10-methylene-tetrahydrofolate dehydrogenase [Clostridium pasteurianum].	41.87	289	157	2	6	294	5	282	1e-66	221
rs:WP_013087597	methenyltetrahydrofolate cyclohydrolase [Candidatus Riesia pediculicola].	42.76	290	156	2	1	290	1	280	1e-66	221
tr:A0A0D2Q6G1_9AGAR	SubName: Full=Unplaced genomic scaffold scaffold_8, whole genome shotgun sequence {ECO:0000313|EMBL:KJA27210.1};	44.11	297	156	4	2	292	7	299	1e-66	234
rs:WP_019671844	5,10-methylene-tetrahydrofolate dehydrogenase [Psychrobacter lutiphocae].	40.21	291	163	2	2	292	5	284	1e-66	221
tr:E9GV59_DAPPU	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EFX76603.1};	43.10	297	160	4	3	294	5	297	1e-66	234
rs:WP_015107971	5,10-methylene-tetrahydrofolate dehydrogenase [Cyanobium gracile].	45.80	286	144	2	3	288	2	276	1e-66	222
rs:XP_007326634	hypothetical protein AGABI1DRAFT_118122 [Agaricus bisporus var. burnettii JB137-S8].	44.11	297	156	4	1	291	1	293	1e-66	234
rs:WP_017181648	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium xenophagum].	46.37	289	136	7	3	286	2	276	1e-66	222
rs:WP_008969677	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobium sp. STM 3843].	44.29	289	155	2	1	289	1	283	1e-66	222
rs:WP_039315863	methenyltetrahydrofolate cyclohydrolase [Clostridium baratii].	41.32	288	158	2	4	291	3	279	1e-66	221
rs:WP_010356169	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces acidiscabies].	41.98	293	158	6	1	292	1	282	1e-66	221
rs:WP_037200181	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. OK494].	43.84	292	156	4	5	292	1	288	1e-66	222
rs:WP_027287360	methenyltetrahydrofolate cyclohydrolase [Rhodovibrio salinarum].	44.48	290	155	2	5	292	1	286	1e-66	222
rs:WP_010157958	5,10-methylene-tetrahydrofolate dehydrogenase [SAR86 cluster bacterium SAR86C].	40.75	292	158	4	1	292	1	277	1e-66	221
rs:WP_021901582	bifunctional protein FolD [Coprobacillus sp. CAG:698].	41.13	282	151	3	5	286	2	268	1e-66	221
rs:XP_011389824	putative trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase MIS1 [Ustilago maydis 521].	45.64	298	151	5	3	293	11	304	1e-66	234
rs:WP_004420820	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira noguchii].	39.32	295	165	2	1	295	1	281	1e-66	221
rs:WP_039910969	methenyltetrahydrofolate cyclohydrolase [Corynebacterium falsenii].	43.20	294	151	6	1	291	4	284	1e-66	221
sp:FOLD_BACSK	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.48	289	157	4	5	293	6	279	1e-66	221
tr:M2SM82_COCH5	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EMD86430.1};	44.18	292	156	3	1	289	487	774	1e-66	237
sp:FOLD_PROMP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.06	288	159	2	6	293	5	287	1e-66	222
rs:WP_016658791	FolD 1 [Acinetobacter indicus].	46.58	292	143	7	2	290	10	291	1e-66	222
rs:WP_046628570	methenyltetrahydrofolate cyclohydrolase [Neorhizobium galegae].	45.24	294	153	4	3	292	2	291	1e-66	222
rs:WP_001070311	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira interrogans].	38.98	295	166	2	1	295	1	281	1e-66	221
rs:WP_036362927	5,10-methylene-tetrahydrofolate cyclohydrolase [Moraxella bovoculi].	39.93	288	162	3	3	290	2	278	1e-66	221
rs:WP_002110013	bifunctional protein FolD [Leptospira interrogans].	38.98	295	166	2	1	295	1	281	1e-66	221
tr:U5H6Y5_USTV1	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KDE06679.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblFungi:MVLG_03025T0};	43.73	295	156	4	3	291	88	378	1e-66	235
rs:WP_005723155	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus crispatus].	46.80	250	122	2	34	283	32	270	1e-66	221
rs:WP_034224709	methenyltetrahydrofolate cyclohydrolase [Actinotalea ferrariae].	43.15	292	157	6	5	292	1	287	1e-66	221
rs:WP_035003099	methenyltetrahydrofolate cyclohydrolase [Corynebacterium jeikeium].	43.30	291	155	4	1	291	4	284	1e-66	221
tr:A0A075GBJ6_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.55	292	141	7	1	292	1	274	1e-66	221
rs:WP_014522356	hypothetical protein [Corynebacterium pseudotuberculosis].	45.24	294	142	6	1	290	1	279	1e-66	221
rs:WP_027283150	methenyltetrahydrofolate cyclohydrolase [Rubritepida flocculans].	44.29	289	147	3	1	289	1	275	1e-66	221
rs:WP_030491861	methenyltetrahydrofolate cyclohydrolase [Micromonospora chokoriensis].	41.78	292	164	4	1	292	1	286	1e-66	221
rs:WP_015662111	bifunctional protein FolD [Streptomyces davawensis].	40.41	292	164	3	1	292	1	282	1e-66	221
rs:WP_010147874	5,10-methylene-tetrahydrofolate dehydrogenase [Serinicoccus profundi].	41.16	294	160	5	1	294	1	281	1e-66	221
rs:XP_007405720	hypothetical protein MELLADRAFT_102871 [Melampsora larici-populina 98AG31].	45.58	294	148	4	5	293	8	294	1e-66	234
rs:WP_014438918	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobium sp. S23321].	43.25	289	158	2	1	289	1	283	1e-66	221
tr:A0A076H670_9SYNE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.88	283	146	3	6	288	15	287	1e-66	222
rs:WP_032796442	methenyltetrahydrofolate cyclohydrolase, partial [Streptomyces sp. HCCB10043].	41.52	289	159	4	1	289	1	279	1e-66	221
sp:FOLD_CENSY	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.41	286	145	5	6	289	1	274	1e-66	221
tr:G7W868_DESOD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576}; Flags: Precursor;	39.44	284	160	3	3	286	24	295	1e-66	222
tr:A0A075FV81_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.21	292	142	7	1	292	1	274	1e-66	221
rs:WP_027755722	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. CNH099].	40.21	286	161	5	1	286	1	276	1e-66	221
rs:WP_013777664	methenyltetrahydrofolate cyclohydrolase [Tepidanaerobacter acetatoxydans].	44.64	289	148	5	3	290	2	279	1e-66	221
rs:XP_001595805	hypothetical protein SS1G_03895 [Sclerotinia sclerotiorum 1980 UF-70].	41.98	293	163	3	1	290	1	289	1e-66	234
tr:W5WTA3_9CORY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.54	294	150	6	1	291	1	281	1e-66	221
rs:WP_019901107	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora arenicola].	41.10	292	166	4	1	292	1	286	1e-66	221
tr:E2S2L0_9CORY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.92	291	158	4	1	291	4	283	1e-66	221
tr:A0A094Q6J9_9ZZZZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGA19002.1};	42.12	292	158	4	1	292	1	281	1e-66	221
tr:K1S3U5_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKC52258.1};	53.93	191	87	1	104	294	2	191	1e-66	218
rs:WP_040329343	methenyltetrahydrofolate cyclohydrolase [Candidatus Clostridium anorexicamassiliense].	40.62	288	160	2	6	293	5	281	1e-66	221
rs:WP_033297716	methenyltetrahydrofolate cyclohydrolase [Streptomyces atroolivaceus].	40.91	286	159	5	1	286	1	276	1e-66	221
rs:WP_041747109	methenyltetrahydrofolate cyclohydrolase [Corynebacterium argentoratense].	41.98	293	159	4	1	293	1	282	1e-66	221
rs:WP_039909011	methenyltetrahydrofolate cyclohydrolase [Micromonospora lupini].	41.44	292	165	4	1	292	1	286	1e-66	221
rs:WP_010578882	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira alexanderi].	39.32	295	165	2	1	295	1	281	1e-66	221
rs:WP_013300074	5,10-methylene-tetrahydrofolate dehydrogenase [Parvularcula bermudensis].	41.44	292	163	3	1	291	1	285	2e-66	221
tr:W5KNV9_ASTMX	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAMXP00000009271};	42.09	297	162	4	3	297	30	318	2e-66	222
rs:WP_039248008	methenyltetrahydrofolate cyclohydrolase [Brevundimonas nasdae].	43.69	293	157	3	3	291	8	296	2e-66	222
tr:H3GAS6_PHYRM	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:Phyra72288};	39.87	301	157	5	4	290	3	293	2e-66	221
tr:U2QKT1_LACBR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.42	284	142	5	5	286	35	307	2e-66	222
tr:W1K3J4_9BRAD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.94	289	156	2	1	289	1	283	2e-66	221
rs:WP_038380435	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium elkanii].	43.36	286	152	3	1	286	1	276	2e-66	221
rs:WP_034984893	methenyltetrahydrofolate cyclohydrolase [Corynebacterium jeikeium].	43.30	291	155	5	1	291	1	281	2e-66	221
sp:FOLD_COREF	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.41	295	145	6	1	291	1	280	2e-66	221
rs:WP_039619612	methenyltetrahydrofolate cyclohydrolase [Rhizobium etli].	44.67	291	150	6	3	291	9	290	2e-66	221
rs:WP_044340197	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus aquimaris].	41.11	287	154	3	5	291	7	278	2e-66	221
rs:WP_039632669	methenyltetrahydrofolate cyclohydrolase [Clostridium argentinense].	41.67	288	157	2	6	293	5	281	2e-66	221
rs:WP_007923468	methylenetetrahydrofolate dehydrogenase [Ktedonobacter racemifer].	41.52	289	159	3	1	289	1	279	2e-66	221
rs:WP_031506276	methenyltetrahydrofolate cyclohydrolase [Streptomyces megasporus].	40.27	293	165	5	1	293	1	283	2e-66	221
tr:S6E103_ZYGB2	SubName: Full=BN860_07228g1_1 {ECO:0000313|EMBL:CDF87476.1};	44.11	297	156	4	1	291	1	293	2e-66	234
tr:A0A075H4Z0_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.03	293	153	5	1	292	14	296	2e-66	221
rs:WP_020441829	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium terpenotabidum].	44.07	295	146	7	1	291	1	280	2e-66	221
rs:WP_013269542	5,10-methylene-tetrahydrofolate dehydrogenase [Brevundimonas subvibrioides].	46.48	284	143	5	2	285	4	278	2e-66	221
sp:FOLD_HERA2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.03	290	161	2	1	290	1	280	2e-66	221
rs:WP_030015854	methenyltetrahydrofolate cyclohydrolase [Curtobacterium sp. S6].	41.41	297	161	6	2	292	7	296	2e-66	221
rs:WP_034617612	methenyltetrahydrofolate cyclohydrolase [Desulfosporosinus sp. Tol-M].	40.14	284	158	3	3	286	2	273	2e-66	221
rs:WP_014136180	5,10-methylene-tetrahydrofolate dehydrogenase [Kitasatospora setae].	42.27	291	157	5	1	291	1	280	2e-66	221
rs:WP_001070309	bifunctional protein FolD [Leptospira interrogans].	38.98	295	166	2	1	295	1	281	2e-66	221
rs:WP_002730806	tetrahydrofolate dehydrogenase [Leptospira borgpetersenii].	38.98	295	166	2	1	295	1	281	2e-66	221
sp:FOLD_LEPBJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.98	295	166	2	1	295	1	281	2e-66	221
rs:WP_030508437	methenyltetrahydrofolate cyclohydrolase [Microbispora rosea].	41.16	294	158	6	1	292	1	281	2e-66	221
rs:XP_010685759	PREDICTED: bifunctional protein FolD 2-like isoform X1 [Beta vulgaris subsp. vulgaris].	40.61	293	168	2	2	292	70	358	2e-66	223
rs:WP_037912504	methenyltetrahydrofolate cyclohydrolase [Streptomyces yeochonensis].	40.41	292	164	5	1	292	1	282	2e-66	221
tr:G0HFW7_CORVD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.01	286	152	4	6	291	3	277	2e-66	221
rs:WP_009470718	5,10-methylene-tetrahydrofolate dehydrogenase [gamma proteobacterium HIMB55].	39.46	294	163	3	1	293	1	280	2e-66	221
sp:FOLD_CORJK	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.64	291	154	5	1	291	1	281	2e-66	221
rs:WP_030914445	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL B-24720].	41.26	286	158	5	1	286	1	276	2e-66	221
rs:WP_009802520	5,10-methylene-tetrahydrofolate dehydrogenase [Oceanicaulis sp. HTCC2633].	43.51	285	155	2	2	286	11	289	2e-66	221
tr:Z2EL32_VIBPH	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:EVU16532.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EVU16532.1}; Flags: Fragment;	50.22	229	110	1	1	229	1	225	2e-66	219
rs:XP_010389031	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Corvus cornix cornix].	44.15	299	109	5	3	295	37	283	2e-66	221
tr:L0P7B5_PNEJ8	SubName: Full=I WGS project CAKM00000000 data, strain SE8, contig 52 {ECO:0000313|EMBL:CCJ28296.1};	41.78	292	163	3	3	291	13	300	2e-66	227
rs:WP_006446643	5,10-methylene-tetrahydrofolate dehydrogenase [Alicyclobacillus hesperidum].	45.42	284	141	4	4	286	3	273	2e-66	221
rs:WP_024338770	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium japonicum].	43.25	289	158	2	1	289	1	283	2e-66	221
rs:WP_025033133	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. DOA9].	43.25	289	158	2	1	289	1	283	2e-66	221
rs:XP_003955833	hypothetical protein KAFR_0B04020 [Kazachstania africana CBS 2517].	42.95	298	160	4	1	292	1	294	2e-66	234
rs:WP_027654256	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	41.10	292	166	4	1	292	1	286	2e-66	221
sp:FOLD_LEPIC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.98	295	166	2	1	295	1	281	2e-66	221
rs:WP_027555763	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. Cp5.3].	44.52	292	155	3	1	292	1	285	2e-66	221
gpu:CP011497_6850	methenyltetrahydrofolate cyclohydrolase [Streptomyces incarnatus]	39.73	292	166	4	1	292	1	282	2e-66	221
tr:M6T6W6_LEPIR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.98	295	166	2	1	295	1	281	2e-66	221
rs:WP_007401984	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Nitrosoarchaeum limnia].	42.86	294	154	4	1	292	1	282	2e-66	221
rs:WP_008041157	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella tamiae].	44.14	290	154	4	4	289	3	288	2e-66	221
rs:WP_030148140	methenyltetrahydrofolate cyclohydrolase [Mycetocola saprophilus].	40.94	298	161	7	1	291	1	290	2e-66	221
rs:WP_016203923	bifunctional protein FolD [Bacillus nealsonii].	42.31	286	150	4	5	290	6	276	2e-66	220
tr:W2G6Q3_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETK78717.1};	41.75	297	154	4	4	289	3	291	2e-66	221
tr:G7EAS1_MIXOS	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GAA99931.1};	43.96	298	153	6	3	291	78	370	2e-66	234
rs:WP_022816007	5,10-methylene-tetrahydrofolate dehydrogenase [Poribacteria bacterium WGA-3G].	43.01	286	148	3	1	286	1	271	2e-66	220
rs:WP_045072887	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. IHBB 11108].	43.52	301	157	6	1	295	1	294	2e-66	221
rs:WP_015610838	FOLD Bifunctional protein FolD [Streptomyces fulvissimus].	41.61	286	157	5	1	286	1	276	2e-66	221
rs:WP_038003178	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Thalassobacter].	43.45	290	160	1	3	292	2	287	2e-66	221
rs:XP_003050730	predicted protein [Nectria haematococca mpVI 77-13-4].	43.94	289	155	3	1	286	1	285	2e-66	234
rs:WP_014847098	5,10-methylene-tetrahydrofolate dehydrogenase [Propionibacterium propionicum].	41.26	286	157	4	1	286	1	275	2e-66	221
tr:F2T1R0_AJEDA	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EGE77394.1};	44.37	293	156	3	1	290	1	289	2e-66	233
tr:C5GH44_AJEDR	SubName: Full=Formate-tetrahydrofolate ligase {ECO:0000313|EMBL:EEQ88439.1};	44.37	293	156	3	1	290	1	289	2e-66	233
rs:WP_010102977	5,10-methylene-tetrahydrofolate dehydrogenase [Verminephrobacter aporrectodeae].	43.36	286	151	3	1	286	1	275	2e-66	221
rs:WP_041626211	methenyltetrahydrofolate cyclohydrolase [Corynebacterium jeikeium].	43.30	291	155	5	1	291	4	284	2e-66	221
rs:WP_042298026	methenyltetrahydrofolate cyclohydrolase [Burkholderia bannensis].	45.33	289	151	3	2	290	3	284	2e-66	221
rs:XP_002627331	formate-tetrahydrofolate ligase [Blastomyces dermatitidis SLH14081].	44.37	293	156	3	1	290	1	289	2e-66	233
rs:WP_027561771	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium].	42.91	289	159	2	1	289	1	283	2e-66	221
rs:WP_027302005	methenyltetrahydrofolate cyclohydrolase [Rhodospirillales bacterium URHD0088].	43.79	290	154	4	3	291	7	288	3e-66	221
rs:WP_007450889	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. W007].	41.26	286	158	4	1	286	1	276	3e-66	221
rs:WP_042752209	5,10-methylene-tetrahydrofolate cyclohydrolase [Leptospira interrogans].	38.98	295	166	2	1	295	1	281	3e-66	220
tr:M5AE68_LACBR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.07	284	143	5	5	286	39	311	3e-66	222
rs:WP_020662447	hypothetical protein [Amycolatopsis benzoatilytica].	41.92	291	153	4	1	290	1	276	3e-66	220
rs:WP_013174615	methylenetetrahydrofolate dehydrogenase [Syntrophothermus lipocalidus].	43.69	293	150	4	1	290	1	281	3e-66	221
tr:W9CR91_9HELO	SubName: Full=Putative C1 tetrahydrofolate synthase {ECO:0000313|EMBL:ESZ97119.1};	41.78	292	163	3	1	289	1	288	3e-66	233
rs:WP_014800075	hypothetical protein [Corynebacterium pseudotuberculosis].	45.52	290	139	6	1	286	1	275	3e-66	220
rs:WP_013241305	hypothetical protein [Corynebacterium pseudotuberculosis].	45.24	294	142	6	1	290	1	279	3e-66	220
tr:M1TP13_9CORY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.61	291	156	4	1	291	1	280	3e-66	220
rs:WP_001070303	bifunctional protein FolD [Leptospira interrogans].	38.98	295	166	2	1	295	1	281	3e-66	220
rs:WP_035159953	methenyltetrahydrofolate cyclohydrolase [Cobetia crustatorum].	44.93	296	149	5	5	291	1	291	3e-66	221
rs:WP_022529235	FolD [Lactobacillus shenzhenensis].	43.62	282	148	3	5	286	4	274	3e-66	220
tr:H2MRN5_ORYLA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSORLP00000021416}; Flags: Fragment;	45.64	298	153	4	1	293	2	295	3e-66	233
tr:A0A0D6MHL7_9PROT	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:GAN53144.1};	44.25	287	154	2	4	290	19	299	3e-66	221
rs:XP_004082411	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Oryzias latipes].	45.64	298	153	4	1	293	1	294	3e-66	233
tr:A0A080ZKW9_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETO67280.1}; Flags: Fragment;	41.75	297	154	4	4	289	19	307	3e-66	221
rs:WP_030338359	methenyltetrahydrofolate cyclohydrolase [Micromonospora parva].	41.44	292	165	4	1	292	1	286	3e-66	220
tr:B2DEV2_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	148	5	6	291	10	288	3e-66	221
rs:XP_003489171	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Bombus impatiens].	44.18	292	155	4	5	292	23	310	3e-66	233
rs:XP_001647037	hypothetical protein Kpol_1050p36 [Vanderwaltozyma polyspora DSM 70294].	44.67	300	154	5	1	293	1	295	3e-66	233
rs:XP_012240602	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Bombus impatiens].	44.18	292	155	4	5	292	9	296	3e-66	233
rs:WP_032756305	methenyltetrahydrofolate cyclohydrolase [Streptomyces alboviridis].	41.61	286	157	5	1	286	1	276	3e-66	221
rs:WP_042056364	methenyltetrahydrofolate cyclohydrolase [Acidomonas methanolica].	44.79	288	153	2	3	290	9	290	3e-66	221
rs:XP_002617026	conserved hypothetical protein [Clavispora lusitaniae ATCC 42720].	41.69	295	163	4	1	290	1	291	3e-66	233
rs:WP_028337383	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium elkanii].	43.94	289	156	2	1	289	1	283	3e-66	221
rs:XP_007911780	putative c-1-tetrahydrofolate synthase protein [Togninia minima UCRPA7].	42.56	289	159	3	1	286	1	285	3e-66	233
rs:WP_030442617	5,10-methylene-tetrahydrofolate cyclohydrolase [Actinoplanes subtropicus].	44.21	285	148	2	6	290	5	278	3e-66	220
rs:WP_017850853	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira interrogans].	38.98	295	166	2	1	295	1	281	3e-66	220
tr:D8LQ10_ECTSI	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CBN74902.1};	41.86	301	155	3	2	286	147	443	3e-66	226
tr:A0A091C7P8_9ENTE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.23	221	100	3	74	294	8	218	3e-66	218
rs:WP_047239630	methenyltetrahydrofolate cyclohydrolase [Corynebacterium epidermidicanis].	42.03	295	154	5	1	292	1	281	3e-66	220
rs:WP_022421000	bifunctional protein FolD, partial [Eubacterium dolichum CAG:375].	51.57	223	97	4	70	291	8	220	3e-66	218
rs:XP_448264	hypothetical protein [Candida glabrata CBS 138].	43.10	297	159	4	3	293	2	294	3e-66	233
tr:A0A0A9WVB6_LYGHE	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:JAG10453.1};	43.73	295	158	4	3	293	7	297	3e-66	233
rs:WP_019888887	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces purpureus].	41.26	286	158	5	1	286	1	276	3e-66	220
tr:T5CAZ5_AJEDE	SubName: Full=Formate-tetrahydrofolate ligase {ECO:0000313|EMBL:EQL38509.1};	44.37	293	156	3	1	290	102	390	3e-66	233
rs:WP_001070304	bifunctional protein FolD [Leptospira interrogans].	38.98	295	166	2	1	295	1	281	3e-66	220
rs:WP_042365534	methenyltetrahydrofolate cyclohydrolase [Streptacidiphilus neutrinimicus].	41.10	292	161	4	1	292	1	281	4e-66	220
rs:WP_031002632	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL WC-3773].	41.44	292	161	5	1	292	1	282	4e-66	220
rs:WP_046692493	5,10-methylene-tetrahydrofolate cyclohydrolase [Leptospira santarosai].	38.98	295	166	2	1	295	1	281	4e-66	220
rs:WP_018272078	hypothetical protein [Bradyrhizobium elkanii].	43.36	286	152	3	1	286	1	276	4e-66	220
sp:FOLD_GLUDA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.58	296	161	2	2	297	20	309	4e-66	221
rs:WP_028343772	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium elkanii].	43.94	289	156	2	1	289	1	283	4e-66	220
rs:WP_031127370	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-623].	41.26	286	158	5	1	286	1	276	4e-66	220
sp:FOLD_RHOPB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.60	289	158	2	1	289	1	284	4e-66	220
rs:XP_002842234	hypothetical protein [Tuber melanosporum Mel28].	45.58	294	150	4	1	291	1	287	4e-66	233
rs:XP_004540875	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Maylandia zebra].	45.30	298	154	4	1	293	1	294	4e-66	233
rs:WP_012796004	5,10-methylene-tetrahydrofolate dehydrogenase [Saccharomonospora viridis].	40.61	293	163	4	1	293	1	282	4e-66	220
rs:XP_005917022	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like isoform X1 [Haplochromis burtoni].	45.30	298	154	4	1	293	1	294	4e-66	233
rs:XP_006682363	hypothetical protein BATDEDRAFT_17961 [Batrachochytrium dendrobatidis JAM81].	44.14	290	155	4	3	289	4	289	4e-66	233
rs:WP_037526870	methenyltetrahydrofolate cyclohydrolase [Sphingomonas wittichii].	45.30	287	150	3	4	290	3	282	4e-66	220
rs:WP_030561694	methenyltetrahydrofolate cyclohydrolase [Streptomyces cyaneofuscatus].	41.61	286	157	5	1	286	1	276	4e-66	220
rs:WP_016544582	tetrahydrofolate dehydrogenase [Leptospira wolffii].	39.32	295	165	2	1	295	1	281	4e-66	220
sp:FOLD_STRGG	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.26	286	158	4	1	286	1	276	4e-66	220
tr:K6KUL8_KLEOX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	52.25	222	96	3	70	291	12	223	4e-66	218
rs:WP_016847250	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobium elkanii].	43.94	289	156	2	1	289	1	283	4e-66	220
tr:A0A060WMF8_ONCMY	SubName: Full=Oncorhynchus mykiss genomic scaffold, scaffold_363 {ECO:0000313|EMBL:CDQ68613.1};	44.97	298	155	4	1	293	1	294	4e-66	233
rs:WP_030798700	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces griseus group].	41.61	286	157	4	1	286	1	276	4e-66	220
rs:WP_040779721	methenyltetrahydrofolate cyclohydrolase, partial [Meiothermus timidus].	41.96	286	156	3	6	291	4	279	4e-66	220
rs:WP_027555340	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. Cp5.3].	43.25	289	158	2	1	289	1	283	4e-66	220
tr:Q4T2B9_TETNG	SubName: Full=Chromosome undetermined SCAF10300, whole genome shotgun sequence {ECO:0000313|EMBL:CAF92963.1};	41.49	323	152	7	3	293	24	341	4e-66	222
rs:WP_026453761	5,10-methylene-tetrahydrofolate cyclohydrolase [Actinopolyspora iraqiensis].	42.21	289	152	3	1	289	1	274	4e-66	220
rs:WP_020045715	hypothetical protein [actinobacterium SCGC AAA027-M14].	42.61	291	156	5	1	291	1	280	4e-66	220
rs:WP_009798511	5,10-methylene-tetrahydrofolate dehydrogenase [Nitrobacter sp. Nb-311A].	43.60	289	157	2	1	289	1	283	4e-66	220
rs:WP_030134701	methenyltetrahydrofolate cyclohydrolase [Mycobacterium neoaurum].	42.47	292	157	4	1	292	1	281	4e-66	220
rs:XP_008609931	hypothetical protein SDRG_05961 [Saprolegnia diclina VS20].	42.03	295	159	3	1	293	3	287	4e-66	220
rs:WP_046085334	methenyltetrahydrofolate cyclohydrolase [Streptomyces yogyakartensis].	41.92	291	159	5	1	291	1	281	4e-66	220
rs:WP_037310039	methenyltetrahydrofolate cyclohydrolase [Saccharomonospora viridis].	40.61	293	163	4	1	293	1	282	4e-66	220
rs:WP_036503095	methenyltetrahydrofolate cyclohydrolase [Novosphingobium sp. AP12].	44.64	289	153	3	4	292	3	284	4e-66	220
sp:FOLD_ORITB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.51	287	159	3	5	290	4	285	4e-66	220
rs:WP_006960187	methylenetetrahydrofolate dehydrogenase [Sphingobium japonicum].	43.79	290	156	3	3	292	2	284	4e-66	220
rs:WP_003928105	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium thermoresistibile].	43.15	292	156	5	1	292	1	282	5e-66	220
tr:J6DUB1_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.79	288	148	6	6	291	10	288	5e-66	220
rs:WP_037078079	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. CCGE 510].	44.79	288	148	6	6	291	12	290	5e-66	220
rs:WP_034488533	methenyltetrahydrofolate cyclohydrolase [Agrobacterium rhizogenes].	43.49	292	157	4	5	292	4	291	5e-66	220
rs:WP_046640990	methenyltetrahydrofolate cyclohydrolase [Neorhizobium galegae].	44.90	294	154	4	3	292	2	291	5e-66	220
tr:L7LTU7_9ACAR	SubName: Full=Putative methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:JAA55022.1};	41.12	321	155	4	3	293	8	324	5e-66	221
rs:WP_018955938	bifunctional protein FolD [Streptomyces sp. CNB091].	41.26	286	158	4	1	286	1	276	5e-66	220
rs:WP_042379557	methenyltetrahydrofolate cyclohydrolase [Corynebacterium resistens].	43.39	295	149	7	1	291	1	281	5e-66	220
rs:WP_038387700	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium elkanii].	43.94	289	156	2	1	289	1	283	5e-66	220
rs:WP_036761364	methenyltetrahydrofolate cyclohydrolase [Peptococcaceae bacterium SCADC1_2_3].	42.16	287	154	4	4	290	3	277	5e-66	220
rs:WP_001070301	bifunctional protein FolD [Leptospira interrogans].	38.98	295	166	2	1	295	1	281	5e-66	220
rs:WP_025777881	methenyltetrahydrofolate cyclohydrolase [Brevibacterium sp. VCM10].	41.89	296	163	5	1	292	1	291	5e-66	220
rs:WP_028177049	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium japonicum].	43.60	289	157	2	1	289	1	283	5e-66	220
rs:XP_007395830	hypothetical protein PHACADRAFT_256172 [Phanerochaete carnosa HHB-10118-sp].	44.78	297	154	4	2	292	3	295	5e-66	233
tr:F7CYX1_CALJA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCJAP00000032874}; Flags: Fragment;	54.22	225	96	3	73	291	5	228	5e-66	218
rs:WP_026296793	methenyltetrahydrofolate cyclohydrolase [Hirschia maritima].	43.55	287	150	5	6	289	5	282	5e-66	220
tr:N1JEB2_BLUG1	SubName: Full=C1-tetrahydrofolate synthase/MIS1 {ECO:0000313|EMBL:CCU81583.1};	42.71	295	155	4	1	292	1	284	5e-66	233
rs:WP_016846483	hypothetical protein [Bradyrhizobium elkanii].	43.36	286	152	3	1	286	1	276	5e-66	220
tr:U5EUM8_9DIPT	SubName: Full=Putative methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:JAB57623.1}; Flags: Fragment;	44.90	294	154	4	3	292	1	290	5e-66	233
rs:WP_007924479	5,10-methylene-tetrahydrofolate dehydrogenase [Janibacter hoylei].	40.27	293	167	5	1	293	1	285	5e-66	220
rs:WP_019143534	5,10-methylene-tetrahydrofolate dehydrogenase [Aeromicrobium massiliense].	41.10	292	161	4	1	292	1	281	5e-66	219
rs:WP_035675858	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium liaoningense].	43.60	289	157	2	1	289	1	283	5e-66	220
rs:WP_018490907	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	41.61	286	157	5	1	286	1	276	5e-66	220
rs:WP_034339355	methenyltetrahydrofolate cyclohydrolase [Commensalibacter sp. MX01].	43.54	294	159	3	1	293	5	292	5e-66	220
rs:WP_030747263	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5135].	41.26	286	158	5	1	286	1	276	5e-66	220
rs:XP_006711987	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X1 [Homo sapiens].	54.22	225	96	3	73	291	5	228	5e-66	218
rs:WP_016757875	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira].	38.98	295	166	2	1	295	1	281	5e-66	219
rs:WP_029476499	hypothetical protein [Dehalococcoidia bacterium SCGC AB-539-J10].	41.78	292	164	4	1	290	1	288	5e-66	220
rs:WP_030874593	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-1868].	41.10	292	162	5	1	292	1	282	5e-66	219
rs:XP_005742863	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Pundamilia nyererei].	45.30	298	154	4	1	293	1	294	5e-66	233
tr:F8E1I9_CORRG	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.39	295	149	7	1	291	13	293	6e-66	220
rs:WP_038583718	methenyltetrahydrofolate cyclohydrolase [Neorhizobium galegae].	44.56	294	155	4	3	292	2	291	6e-66	220
rs:WP_029472147	hypothetical protein [Clostridiales bacterium VE202-08].	41.38	290	160	3	1	290	1	280	6e-66	219
rs:WP_037085238	methenyltetrahydrofolate cyclohydrolase [Rhizobium vignae].	44.90	294	154	4	3	292	2	291	6e-66	220
rs:WP_016340859	methylenetetrahydrofolate dehydrogenase [Spiroplasma syrphidicola].	42.32	293	151	6	1	287	1	281	6e-66	219
tr:A0A062UYX4_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.06	286	149	2	5	290	12	286	6e-66	220
sp:C1TM_SCHPO	RecName: Full=C-1-tetrahydrofolate synthase, mitochondrial; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3; Flags: Precursor;	47.10	293	143	5	2	290	35	319	6e-66	233
rs:WP_022441886	bifunctional protein FolD [Clostridium sp. CAG:768].	44.17	283	142	5	5	286	4	271	6e-66	219
tr:G0SY32_RHOG2	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:EGU12426.1};	43.29	298	156	5	3	291	70	363	6e-66	233
rs:WP_035703096	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. CCBAU 43298].	43.25	289	158	2	1	289	1	283	6e-66	220
rs:WP_022604405	5,10-methylene-tetrahydrofolate dehydrogenase [Rubidibacter lacunae].	45.14	288	150	3	1	286	4	285	6e-66	220
rs:WP_026881321	hypothetical protein [Clostridium akagii].	40.28	288	161	2	6	293	5	281	6e-66	219
rs:WP_035602832	methenyltetrahydrofolate cyclohydrolase [Hyphomonas polymorpha].	45.89	292	146	5	1	289	1	283	6e-66	220
tr:E9H7E9_DAPPU	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EFX72364.1};	42.71	295	160	4	3	292	41	331	6e-66	221
sp:FOLD_MYCVP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.71	286	151	5	1	286	4	279	6e-66	219
tr:I4MY90_9PSED	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.29	289	148	5	2	289	3	279	6e-66	220
gp:HB883503_1	Sequence 16178 from Patent EP2096177. [Schizosaccharomyces pombe]	47.10	293	143	5	2	290	32	316	6e-66	233
rs:WP_046568425	methenyltetrahydrofolate cyclohydrolase [Micromonospora sp. HK10].	41.10	292	166	4	1	292	1	286	6e-66	219
rs:WP_020520355	5,10-methylene-tetrahydrofolate dehydrogenase [Catelliglobosispora koreensis].	39.93	293	169	4	1	293	1	286	6e-66	219
tr:A0A094QSG8_9ZZZZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGA17681.1};	42.66	286	153	5	1	286	1	275	6e-66	219
rs:XP_010699853	C-1-tetrahydrofolate synthase, cytoplasmic, putative [Leishmania panamensis].	41.41	297	165	4	2	293	4	296	6e-66	220
rs:WP_028471022	5,10-methylene-tetrahydrofolate cyclohydrolase [Neptunomonas japonica].	40.69	290	158	2	1	290	1	276	7e-66	219
rs:WP_002523525	5,10-methylene-tetrahydrofolate dehydrogenase [Propionibacterium acnes].	40.89	291	162	4	1	291	1	281	7e-66	219
rs:WP_034483606	methenyltetrahydrofolate cyclohydrolase [Agrobacterium rhizogenes].	43.54	294	158	4	3	292	4	293	7e-66	220
tr:C6H445_AJECH	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:EER44547.1};	43.34	293	159	3	1	290	1	289	7e-66	232
tr:I0V0U9_9PSEU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.58	291	159	4	5	295	2	281	7e-66	219
rs:WP_007024115	5,10-methylene-tetrahydrofolate dehydrogenase [Saccharomonospora paurometabolica].	42.56	289	151	3	1	289	1	274	7e-66	220
rs:WP_040423900	methenyltetrahydrofolate cyclohydrolase [Corynebacterium genitalium].	40.89	291	162	3	1	291	1	281	7e-66	219
gp:BA000035_659	putative methylenetetrahydrofolate dehydrogenase(NADP+)/methenyltetrahydrofolate cyclohydrolase [Corynebacterium efficiens YS-314]	44.37	284	143	5	12	291	20	292	7e-66	220
tr:V5GXR2_ANOGL	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:JAB65148.1};	44.22	294	156	4	3	292	18	307	7e-66	225
rs:WP_030889036	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5053].	41.10	292	162	5	1	292	1	282	7e-66	219
rs:WP_029081214	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. th.b2].	43.94	289	156	2	1	289	1	283	7e-66	219
rs:WP_014177344	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces bingchenggensis].	42.31	286	155	5	1	286	1	276	7e-66	220
tr:M0S110_MUSAM	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:GSMUA_Achr1P18520_001};	49.55	224	107	2	70	291	12	231	7e-66	218
rs:WP_034764953	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus vietnamensis].	41.11	287	154	3	5	291	7	278	7e-66	219
rs:WP_009021716	5,10-methylene-tetrahydrofolate dehydrogenase [Luminiphilus syltensis].	40.14	294	161	3	1	293	1	280	7e-66	219
gp:CP003797_504	tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein [Chlamydia psittaci CP3]	47.70	239	123	2	54	291	2	239	7e-66	218
rs:WP_013348078	5,10-methylene-tetrahydrofolate dehydrogenase [Arthrobacter arilaitensis].	41.22	296	159	6	1	292	1	285	7e-66	219
rs:WP_014366563	hypothetical protein [Corynebacterium pseudotuberculosis].	45.24	294	142	6	1	290	1	279	7e-66	219
rs:WP_028152814	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium japonicum].	42.91	289	159	2	1	289	1	283	8e-66	219
rs:WP_027580687	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. Ai1a-2].	43.25	289	158	2	1	289	1	283	8e-66	219
rs:WP_038548720	methenyltetrahydrofolate cyclohydrolase [Neorhizobium galegae].	44.56	294	155	4	3	292	2	291	8e-66	220
rs:WP_010574562	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira kmetyi].	39.66	295	164	2	1	295	1	281	8e-66	219
rs:WP_021753006	tetrahydrofolate dehydrogenase [Gemella bergeri].	42.07	290	155	4	3	291	2	279	8e-66	219
tr:U3GYC8_9CORY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.01	288	156	4	6	293	3	279	8e-66	219
rs:WP_030912569	methenyltetrahydrofolate cyclohydrolase [Streptosporangium amethystogenes].	41.30	293	157	6	1	291	1	280	8e-66	219
rs:WP_027983482	hypothetical protein, partial [delta proteobacterium JGI 0000059-O15].	50.00	232	106	2	54	285	2	223	8e-66	218
rs:XP_003292911	hypothetical protein DICPUDRAFT_157687 [Dictyostelium purpureum].	38.83	291	171	3	5	289	74	363	8e-66	223
rs:WP_004753878	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira kirschneri].	38.64	295	167	2	1	295	1	281	8e-66	219
rs:WP_008136726	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobium sp. YR681].	42.91	289	159	2	1	289	1	283	8e-66	219
tr:A0A0B8RIF3_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.45	290	155	3	1	289	1	282	8e-66	219
rs:XP_006564487	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X2 [Apis mellifera].	43.77	297	149	6	2	292	27	311	8e-66	221
rs:WP_030263267	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL B-24484].	42.61	291	156	5	1	291	1	280	8e-66	219
rs:WP_025250664	methenyltetrahydrofolate cyclohydrolase [Spiroplasma sabaudiense].	42.41	290	156	4	4	293	2	280	8e-66	219
rs:WP_030457330	methenyltetrahydrofolate cyclohydrolase [Kitasatospora sp. NRRL B-11411].	42.27	291	157	5	1	291	1	280	8e-66	219
rs:WP_040452279	hypothetical protein, partial [Holdemania massiliensis].	52.73	220	94	3	72	291	2	211	9e-66	217
rs:WP_027543867	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. WSM2254].	43.25	289	158	2	1	289	1	283	9e-66	219
rs:WP_035979299	methenyltetrahydrofolate cyclohydrolase [Kozakia baliensis].	43.84	292	158	2	2	293	10	295	9e-66	219
rs:WP_020765129	MULTISPECIES: tetrahydrofolate dehydrogenase [Leptospira].	38.64	295	167	2	1	295	1	281	9e-66	219
rs:WP_021080608	methylenetetrahydrofolate dehydrogenase [Bradyrhizobium sp. DFCI-1].	43.36	286	152	3	1	286	1	276	9e-66	219
rs:XP_006632525	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Lepisosteus oculatus].	44.82	299	154	5	1	293	1	294	9e-66	232
rs:XP_005806196	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Xiphophorus maculatus].	44.63	298	156	4	1	293	1	294	9e-66	232
rs:XP_008397696	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Poecilia reticulata].	44.63	298	156	4	1	293	1	294	9e-66	232
rs:WP_042383320	methenyltetrahydrofolate cyclohydrolase [Streptacidiphilus melanogenes].	40.75	292	162	4	1	292	1	281	9e-66	219
rs:WP_037138671	methenyltetrahydrofolate cyclohydrolase [Rhizobium leguminosarum].	44.33	291	151	6	3	291	9	290	1e-65	219
tr:I0LBS9_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.10	292	166	4	1	292	2	287	1e-65	219
rs:WP_021107783	MULTISPECIES: methylenetetrahydrofolate dehydrogenase [Propionibacterium].	40.89	291	162	4	1	291	1	281	1e-65	219
rs:WP_047017645	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. CNQ-509].	40.49	284	159	5	1	284	1	274	1e-65	220
rs:XP_012192826	hypothetical protein PHSY_006839 [Pseudozyma hubeiensis SY62].	44.97	298	153	5	3	293	84	377	1e-65	232
rs:WP_026819193	methenyltetrahydrofolate cyclohydrolase [Arthrobacter castelli].	41.30	293	160	5	6	291	1	288	1e-65	219
rs:WP_004427664	tetrahydrofolate dehydrogenase [Leptospira noguchii].	38.64	295	167	2	1	295	1	281	1e-65	219
rs:WP_008040688	5,10-methylene-tetrahydrofolate dehydrogenase [Bartonella tamiae].	43.79	290	155	4	4	289	3	288	1e-65	219
rs:WP_045797287	5,10-methylene-tetrahydrofolate cyclohydrolase [Orientia chuto].	41.96	286	160	3	6	290	1	281	1e-65	219
rs:WP_028821929	methenyltetrahydrofolate cyclohydrolase [Propionimicrobium lymphophilum].	42.66	286	153	4	1	286	1	275	1e-65	219
rs:WP_042420080	methenyltetrahydrofolate cyclohydrolase [Streptacidiphilus anmyonensis].	40.75	292	162	4	1	292	1	281	1e-65	219
rs:WP_045665363	methenyltetrahydrofolate cyclohydrolase [Rhodospirillaceae bacterium BRH_c57].	45.67	289	148	4	6	292	11	292	1e-65	219
rs:WP_037575510	methenyltetrahydrofolate cyclohydrolase [Streptacidiphilus oryzae].	42.96	284	152	4	1	284	1	274	1e-65	219
rs:WP_004462989	5,10-methylene-tetrahydrofolate dehydrogenase [Moraxella catarrhalis].	40.83	289	160	3	3	291	2	279	1e-65	219
rs:WP_035107863	methenyltetrahydrofolate cyclohydrolase [Corynebacterium callunae].	43.66	284	145	5	12	291	11	283	1e-65	219
rs:WP_036460222	methenyltetrahydrofolate cyclohydrolase [Mycobacterium sp. UNCCL9].	42.12	292	158	4	1	292	1	281	1e-65	219
rs:WP_012887993	5,10-methylene-tetrahydrofolate dehydrogenase [Streptosporangium roseum].	42.32	293	154	6	1	291	1	280	1e-65	219
rs:WP_038932601	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium japonicum].	42.91	289	159	2	1	289	1	283	1e-65	219
tr:G0PV27_STRGR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.26	286	158	4	1	286	27	302	1e-65	220
sp:FOLD_OLICO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.21	289	161	2	1	289	1	283	1e-65	219
rs:WP_046648385	methenyltetrahydrofolate cyclohydrolase [Corynebacterium minutissimum].	43.39	295	148	6	1	291	1	280	1e-65	219
rs:XP_001382486	tetrahydrofolate synthase [Scheffersomyces stipitis CBS 6054].	44.26	296	156	4	1	291	1	292	1e-65	232
rs:WP_034997377	methenyltetrahydrofolate cyclohydrolase [Corynebacterium sp. GD7].	40.41	292	164	3	1	292	1	282	1e-65	219
rs:WP_010169032	5,10-methylene-tetrahydrofolate dehydrogenase [Epulopiscium sp. 'N.t. morphotype B'].	42.81	285	150	3	6	290	8	279	1e-65	219
tr:G0TXW2_TRYVY	SubName: Full=Putative C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:CCC48805.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CCC48805.1};	41.22	296	165	4	3	293	4	295	1e-65	219
sp:FOLD_CORA7	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.05	295	149	6	1	291	1	280	1e-65	219
tr:A0A072C7R3_RHILP	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.33	291	151	6	3	291	7	288	1e-65	219
rs:XP_002770508	DEHA2E18414p [Debaryomyces hansenii CBS767].	42.30	305	156	3	1	289	29	329	1e-65	232
rs:WP_033817972	methenyltetrahydrofolate cyclohydrolase [Kitasatospora sp. MBT63].	41.92	291	159	4	1	291	1	281	1e-65	219
rs:WP_026573671	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. UNC438CL73TsuS30].	41.64	293	156	4	1	293	1	278	1e-65	219
tr:W9FTZ9_STRFL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.26	286	158	4	1	286	1	276	1e-65	219
rs:WP_030542691	methenyltetrahydrofolate cyclohydrolase [Streptomyces albus].	40.07	292	165	5	1	292	1	282	1e-65	219
rs:WP_014794710	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Desulfitobacterium].	40.49	284	157	3	3	286	2	273	1e-65	219
rs:WP_030579589	methenyltetrahydrofolate cyclohydrolase [Streptomyces anulatus].	41.26	286	158	4	1	286	1	276	1e-65	219
tr:G6XJT5_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.41	290	161	2	1	290	6	289	1e-65	219
rs:WP_025976804	methenyltetrahydrofolate cyclohydrolase [Brevundimonas naejangsanensis].	42.86	294	160	2	3	292	8	297	1e-65	219
rs:WP_042195897	methenyltetrahydrofolate cyclohydrolase [Kibdelosporangium sp. MJ126-NF4].	41.03	290	160	5	1	290	1	279	1e-65	219
rs:WP_044539319	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. LTSP885].	43.94	289	156	2	1	289	1	283	1e-65	219
rs:WP_022457674	bifunctional protein FolD [Fusobacterium sp. CAG:439].	43.16	285	146	5	3	286	2	271	1e-65	218
rs:WP_030905097	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-384].	42.27	291	157	5	1	291	1	280	1e-65	219
rs:WP_042819842	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. RSD-27].	41.44	292	161	5	1	292	1	282	1e-65	219
tr:S9PR17_SCHOY	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:EPX71591.1};	46.15	286	138	4	9	292	25	296	1e-65	231
rs:WP_040508695	methenyltetrahydrofolate cyclohydrolase [Gluconobacter morbifer].	42.41	290	161	2	1	290	14	297	1e-65	219
rs:WP_030903635	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5126].	40.61	293	164	5	1	293	1	283	1e-65	219
rs:WP_045636574	methenyltetrahydrofolate cyclohydrolase [Peptococcaceae bacterium BRH_c4a].	40.00	290	162	4	1	290	1	278	1e-65	219
sp:FOLD_THEFY	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.98	293	159	5	1	293	1	282	1e-65	219
rs:WP_029722232	methenyltetrahydrofolate cyclohydrolase [Saccharopolyspora rectivirgula].	40.75	292	162	5	1	292	1	281	1e-65	219
rs:WP_005313237	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces pristinaespiralis].	41.26	286	158	5	1	286	1	276	1e-65	219
rs:WP_002741398	tetrahydrofolate dehydrogenase [Leptospira borgpetersenii].	38.64	295	167	2	1	295	1	281	1e-65	219
rs:WP_002514746	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Propionibacterium].	40.89	291	162	4	1	291	1	281	1e-65	219
rs:WP_034465500	methenyltetrahydrofolate cyclohydrolase [Afipia sp. P52-10].	42.56	289	160	2	1	289	1	283	1e-65	219
rs:WP_037953392	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. PRh5].	42.66	286	154	5	1	286	1	276	1e-65	219
rs:WP_043570648	methenyltetrahydrofolate cyclohydrolase [Actinopolyspora erythraea].	40.41	292	163	5	1	292	1	281	1e-65	218
rs:WP_019710445	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces xinghaiensis].	39.73	292	166	5	1	292	1	282	1e-65	219
rs:WP_039165573	methenyltetrahydrofolate cyclohydrolase, partial [Leisingera sp. ANG-M1].	46.72	259	131	2	34	292	2	253	1e-65	218
rs:WP_030084515	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	41.26	286	158	4	1	286	1	276	1e-65	219
rs:WP_046646581	methenyltetrahydrofolate cyclohydrolase [Corynebacterium striatum].	43.05	295	149	6	1	291	1	280	1e-65	218
rs:WP_012483711	5,10-methylene-tetrahydrofolate dehydrogenase [Rhizobium etli].	44.10	288	150	6	6	291	12	290	1e-65	219
rs:XP_007628810	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X5 [Cricetulus griseus].	44.63	298	117	4	3	294	113	368	1e-65	221
rs:WP_039206287	methenyltetrahydrofolate cyclohydrolase [Brevibacterium linens].	41.89	296	163	5	1	292	1	291	1e-65	219
rs:WP_021078232	FolD protein [Bradyrhizobium sp. DFCI-1].	44.29	289	155	2	1	289	1	283	1e-65	219
rs:WP_008490634	tetrahydrofolate dehydrogenase [SAR86 cluster bacterium SAR86E].	42.52	294	153	6	1	293	1	279	1e-65	218
rs:WP_034656544	methenyltetrahydrofolate cyclohydrolase [Corynebacterium striatum].	43.05	295	149	6	1	291	1	280	1e-65	218
rs:WP_043301438	methenyltetrahydrofolate cyclohydrolase [Pseudomonas sp. M47T1].	44.25	287	147	5	4	289	2	276	1e-65	219
rs:WP_036334182	methenyltetrahydrofolate cyclohydrolase [Modestobacter sp. KNN45-2b].	43.15	292	155	4	1	292	1	281	2e-65	219
rs:WP_010058645	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	41.26	286	158	4	1	286	1	276	2e-65	219
rs:WP_035156879	methenyltetrahydrofolate cyclohydrolase [Lactobacillus reuteri].	45.45	286	140	4	5	286	4	277	2e-65	218
rs:WP_042456389	methenyltetrahydrofolate cyclohydrolase [Streptacidiphilus jiangxiensis].	40.75	292	162	4	1	292	1	281	2e-65	218
rs:WP_039155304	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium japonicum].	42.56	289	160	2	1	289	1	283	2e-65	219
tr:W4TFY3_PROAA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.89	291	162	4	1	291	1	281	2e-65	218
rs:WP_015311542	5,10-methylene-tetrahydrofolate dehydrogenase [Thermoanaerobacterium thermosaccharolyticum].	39.45	289	159	4	5	293	2	274	2e-65	218
rs:WP_014105833	5,10-methylene-tetrahydrofolate dehydrogenase [Komagataeibacter medellinensis].	43.94	289	156	2	2	290	14	296	2e-65	219
rs:WP_022795857	5,10-methylene-tetrahydrofolate dehydrogenase [Bavariicoccus seileri].	43.10	290	147	6	6	292	4	278	2e-65	218
rs:WP_034103032	methenyltetrahydrofolate cyclohydrolase [Desulfotomaculum sp. BICA1-6].	41.03	290	160	3	1	290	1	279	2e-65	218
rs:XP_004499610	PREDICTED: bifunctional protein FolD 1, mitochondrial-like [Cicer arietinum].	39.46	294	171	3	2	293	68	356	2e-65	221
tr:W1QFS4_OGAPD	SubName: Full=C-1-tetrahydrofolate synthase, mitochondrial {ECO:0000313|EMBL:ESW98763.1}; EC=1.5.1.5 {ECO:0000313|EMBL:ESW98763.1};	42.91	296	162	3	1	293	22	313	2e-65	231
rs:WP_019053345	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium xenophagum].	43.79	290	156	3	3	292	2	284	2e-65	218
rs:XP_002488028	C1 tetrahydrofolate synthase, putative [Talaromyces stipitatus ATCC 10500].	43.00	293	160	3	1	290	1	289	2e-65	231
rs:WP_041152301	methenyltetrahydrofolate cyclohydrolase [Lactobacillus kunkeei].	42.81	292	153	6	3	292	2	281	2e-65	218
rs:WP_015582236	methylenetetrahydrofolate dehydrogenase [Propionibacterium avidum].	41.58	291	160	4	1	291	1	281	2e-65	218
tr:C2CQB2_CORST	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.05	295	149	6	1	291	4	283	2e-65	218
rs:WP_026166049	methenyltetrahydrofolate cyclohydrolase [Corynebacterium mastitidis].	42.81	292	154	6	1	291	1	280	2e-65	218
rs:WP_013297790	5,10-methylene-tetrahydrofolate dehydrogenase [Thermoanaerobacterium thermosaccharolyticum].	39.45	289	159	4	5	293	2	274	2e-65	218
rs:WP_020515423	5,10-methylene-tetrahydrofolate dehydrogenase [Actinoplanes globisporus].	42.41	290	161	4	1	290	1	284	2e-65	218
tr:E7A2M1_SPORE	SubName: Full=Chromosome 8 complete DNA sequence {ECO:0000313|EMBL:CBQ73728.1};	44.63	298	154	5	3	293	78	371	2e-65	231
rs:WP_034145676	methenyltetrahydrofolate cyclohydrolase [Desulfosporosinus sp. BICA1-9].	38.73	284	162	3	3	286	2	273	2e-65	218
rs:WP_047178373	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. MNU77].	40.91	286	159	4	1	286	1	276	2e-65	219
rs:WP_004040781	FolD 1 [Lactobacillus sp. ASF360].	41.96	286	153	4	3	286	2	276	2e-65	218
rs:XP_009216202	C-1-tetrahydrofolate synthase [Gaeumannomyces graminis var. tritici R3-111a-1].	43.90	287	154	3	1	284	146	428	2e-65	232
rs:XP_001525302	C-1-tetrahydrofolate synthase, mitochondrial precursor [Lodderomyces elongisporus NRRL YB-4239].	42.37	295	161	4	1	290	1	291	2e-65	231
rs:WP_034531063	methenyltetrahydrofolate cyclohydrolase [Lactobacillus kunkeei].	43.15	292	152	6	3	292	2	281	2e-65	218
rs:XP_002596786	hypothetical protein BRAFLDRAFT_120483 [Branchiostoma floridae].	44.33	300	154	7	1	293	1	294	2e-65	231
rs:WP_021968807	bifunctional protein FolD [Mycoplasma sp. CAG:956].	41.90	284	151	3	5	288	3	272	2e-65	218
rs:WP_038385874	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium elkanii].	42.66	286	154	3	1	286	1	276	2e-65	218
tr:I2FYP2_USTH4	SubName: Full=Probable MIS1-C1-tetrahydrofolate synthase, mitochondrial {ECO:0000313|EMBL:CCF52035.1};	44.63	298	154	5	3	293	11	304	2e-65	231
rs:WP_045004508	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. LTSP857].	42.91	289	159	2	1	289	1	283	2e-65	218
tr:U6DIQ0_NEOVI	SubName: Full=Probable bifunctional methylenetetrahydrofolate {ECO:0000313|EMBL:CCP82471.1}; Flags: Fragment;	51.67	240	109	3	61	294	4	242	2e-65	217
rs:WP_004758398	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira kirschneri].	38.31	295	168	2	1	295	1	281	2e-65	218
rs:WP_002747728	tetrahydrofolate dehydrogenase [Leptospira borgpetersenii].	38.64	295	167	2	1	295	1	281	2e-65	218
rs:WP_040429616	methenyltetrahydrofolate cyclohydrolase [Corynebacterium pilosum].	41.44	292	160	4	1	292	4	284	2e-65	218
rs:WP_013735826	5,10-methylene-tetrahydrofolate dehydrogenase [Verrucosispora maris].	41.10	292	166	4	1	292	1	286	2e-65	218
rs:WP_020767783	tetrahydrofolate dehydrogenase [Leptospira kirschneri].	38.64	295	167	2	1	295	1	281	2e-65	218
rs:WP_004808916	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Propionibacterium].	40.89	291	162	4	1	291	1	281	2e-65	218
rs:WP_038609859	methenyltetrahydrofolate cyclohydrolase [Corynebacterium ureicelerivorans].	40.41	292	164	3	1	292	1	282	2e-65	218
rs:WP_045680375	methenyltetrahydrofolate cyclohydrolase [Martelella endophytica].	43.20	294	159	4	3	292	2	291	2e-65	219
rs:WP_035331562	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus firmus].	40.83	289	156	3	5	293	7	280	2e-65	218
rs:WP_001070310	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira interrogans].	38.64	295	167	2	1	295	1	281	2e-65	218
rs:WP_006716090	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfitobacterium metallireducens].	39.44	284	160	3	3	286	2	273	2e-65	218
rs:XP_011103630	ade3p [Saccharomyces arboricola H-6].	42.24	303	160	5	1	292	1	299	2e-65	231
rs:WP_028812278	methenyltetrahydrofolate cyclohydrolase [Streptomyces flavidovirens].	41.26	286	158	5	1	286	1	276	2e-65	218
tr:H3DJB2_TETNG	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTNIP00000020608}; Flags: Fragment;	44.63	298	156	4	1	293	2	295	2e-65	231
rs:WP_019254004	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus reuteri].	45.10	286	141	4	5	286	4	277	2e-65	218
sp:FOLD_MYCSS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.41	290	157	4	1	290	1	280	2e-65	218
tr:A5B5E0_VITVI	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CAN65246.1};	41.00	300	164	3	2	292	63	358	2e-65	220
rs:XP_008279648	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Stegastes partitus].	44.97	298	155	4	1	293	1	294	2e-65	231
rs:WP_014306563	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium diphtheriae].	42.57	296	151	6	1	292	1	281	2e-65	218
rs:XP_007549239	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Poecilia formosa].	44.30	298	157	4	1	293	1	294	2e-65	231
sp:FOLD2_DESHY	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.14	284	158	3	3	286	2	273	2e-65	218
rs:WP_018510490	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. ScaeMP-e10].	41.26	286	158	5	1	286	1	276	2e-65	218
tr:B9JRS8_AGRVS	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.33	259	131	4	38	292	1	255	3e-65	217
rs:XP_007374184	mitochondrial C1 tetrahydrofolate synthase precursor [Spathaspora passalidarum NRRL Y-27907].	45.07	304	148	4	1	289	28	327	3e-65	231
tr:A0A0C3GA26_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIM93050.1};	41.78	292	163	3	1	289	1	288	3e-65	231
tr:D7WAM5_9CORY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.91	286	159	3	6	291	9	284	3e-65	218
rs:WP_027929328	methenyltetrahydrofolate cyclohydrolase [Amycolatopsis thermoflava].	42.12	292	159	4	1	292	1	282	3e-65	218
rs:XP_006786366	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Neolamprologus brichardi].	45.30	298	154	4	1	293	1	294	3e-65	231
tr:A0A017SQM6_9EURO	SubName: Full=Putative C1 tetrahydrofolate synthase {ECO:0000313|EMBL:EYE99282.1};	45.39	293	153	3	1	290	112	400	3e-65	231
rs:WP_004780243	tetrahydrofolate dehydrogenase [Leptospira kirschneri].	38.31	295	168	2	1	295	1	281	3e-65	218
rs:XP_002551855	KLTH0B01496p [Lachancea thermotolerans].	41.47	299	164	5	1	293	1	294	3e-65	231
rs:WP_002543066	5,10-methylene-tetrahydrofolate dehydrogenase [Propionibacterium acnes].	40.55	291	163	4	1	291	1	281	3e-65	218
tr:G9XL64_DESHA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.14	284	158	3	3	286	12	283	3e-65	218
tr:A0A078AJ08_STYLE	SubName: Full=Amino acid dehydrogenase family protein {ECO:0000313|EMBL:CDW81452.1};	41.22	262	146	3	34	291	14	271	3e-65	218
rs:WP_020773465	tetrahydrofolate dehydrogenase [Leptospira alstonii].	38.98	295	166	2	1	295	1	281	3e-65	218
tr:A0A097STP7_9MOLU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.29	289	147	5	5	290	3	280	3e-65	218
rs:WP_002177746	tetrahydrofolate dehydrogenase [Leptospira interrogans].	38.31	295	168	2	1	295	1	281	3e-65	218
rs:WP_038588611	methenyltetrahydrofolate cyclohydrolase [Corynebacterium imitans].	40.07	287	161	4	6	292	9	284	3e-65	218
rs:WP_030708990	methenyltetrahydrofolate cyclohydrolase [Streptomyces griseus].	40.91	286	159	4	1	286	1	276	3e-65	218
rs:WP_029417827	methenyltetrahydrofolate cyclohydrolase [Brevundimonas bacteroides].	43.88	294	157	3	3	292	8	297	3e-65	218
rs:WP_015615964	5,10-methylene-tetrahydrofolate dehydrogenase [Clostridium pasteurianum].	40.83	289	160	2	6	294	5	282	3e-65	218
rs:WP_007078514	5,10-methylene-tetrahydrofolate dehydrogenase [Aeromicrobium marinum].	41.26	286	158	4	1	286	1	276	3e-65	218
rs:WP_023985407	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium].	41.92	291	158	4	1	291	1	280	3e-65	218
rs:WP_015237394	5,10-methylene-tetrahydrofolate dehydrogenase [Deinococcus peraridilitoris].	45.24	294	149	4	1	294	1	282	3e-65	218
rs:WP_043397795	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Mycobacterium].	43.00	293	156	4	1	293	1	282	3e-65	218
rs:WP_020763762	tetrahydrofolate dehydrogenase [Leptospira kirschneri].	38.31	295	168	2	1	295	1	281	3e-65	218
rs:WP_014051218	5,10-methylene-tetrahydrofolate dehydrogenase [halophilic archaeon DL31].	43.25	289	160	2	3	291	35	319	3e-65	219
rs:WP_017214238	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira noguchii].	38.31	295	168	2	1	295	1	281	3e-65	218
rs:WP_046325070	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus melliventris].	40.69	290	158	4	3	291	2	278	3e-65	218
rs:WP_019519641	5,10-methylene-tetrahydrofolate dehydrogenase [Moraxella boevrei].	40.07	292	162	5	3	293	2	281	3e-65	218
rs:WP_004442405	tetrahydrofolate dehydrogenase [Leptospira noguchii].	38.31	295	168	2	1	295	1	281	3e-65	218
rs:WP_028653228	methenyltetrahydrofolate cyclohydrolase [Nocardioides halotolerans].	41.10	292	159	5	1	292	1	279	3e-65	218
sp:FOLD_NITWN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.25	289	158	2	1	289	1	283	3e-65	218
rs:WP_003669562	5,10-methylene-tetrahydrofolate dehydrogenase [Moraxella catarrhalis].	41.03	290	158	5	3	291	2	279	3e-65	218
rs:WP_003663481	5,10-methylene-tetrahydrofolate dehydrogenase [Moraxella catarrhalis].	41.03	290	158	5	3	291	2	279	3e-65	218
rs:WP_007604163	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobium sp. WSM471].	42.91	289	159	2	1	289	1	283	3e-65	218
rs:WP_028339250	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium elkanii].	43.01	286	153	3	1	286	1	276	3e-65	218
tr:A0A024QWE9_MYCNE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.12	292	158	4	1	292	4	284	3e-65	218
sp:FOLD_BRADU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.91	289	159	2	1	289	1	283	3e-65	218
rs:WP_016665972	FolD protein [Propionibacterium sp. HGH0353].	40.89	291	162	4	1	291	1	281	3e-65	218
rs:XP_012209459	hypothetical protein SPRG_14947 [Saprolegnia parasitica CBS 223.65].	41.36	295	164	3	1	293	3	290	4e-65	218
rs:WP_002528638	5,10-methylene-tetrahydrofolate dehydrogenase [Propionibacterium humerusii].	40.55	291	163	4	1	291	1	281	4e-65	218
rs:XP_001562267	putative C-1-tetrahydrofolate synthase,cytoplasmic [Leishmania braziliensis MHOM/BR/75/M2904].	41.08	297	166	4	2	293	4	296	4e-65	218
tr:A0A087YDY2_POEFO	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPFOP00000016235};	43.05	295	155	7	3	291	24	311	4e-65	219
tr:G3MGH8_9ACAR	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:AEO32596.1}; Flags: Fragment;	40.14	289	167	2	7	293	1	285	4e-65	218
rs:WP_038272920	methenyltetrahydrofolate cyclohydrolase [actinobacterium acAMD-2].	43.71	286	150	5	1	286	1	275	4e-65	218
rs:XP_003035759	hypothetical protein SCHCODRAFT_81176 [Schizophyllum commune H4-8].	43.24	296	158	4	2	291	26	317	4e-65	230
rs:WP_045012805	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. LTSP849].	42.91	289	159	2	1	289	1	283	4e-65	218
rs:XP_002789753	C-1-tetrahydrofolate synthase [Paracoccidioides sp. 'lutzii' Pb01].	44.03	293	157	3	1	290	1	289	4e-65	230
rs:WP_016548528	tetrahydrofolate dehydrogenase [Leptospira fainei].	39.66	295	164	2	1	295	1	281	4e-65	218
rs:WP_005390393	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium glucuronolyticum].	41.78	292	159	4	1	292	1	281	4e-65	218
rs:WP_018834730	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. CNQ766].	39.51	286	163	5	1	286	1	276	4e-65	218
rs:WP_040356386	methenyltetrahydrofolate cyclohydrolase [Corynebacterium ammoniagenes].	43.99	291	149	4	1	291	1	277	4e-65	217
rs:WP_005394982	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium glucuronolyticum].	41.78	292	159	4	1	292	1	281	4e-65	218
rs:WP_010569977	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira broomii].	39.32	295	165	2	1	295	1	281	4e-65	218
rs:WP_001070307	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira interrogans].	38.64	295	167	2	1	295	1	281	4e-65	217
rs:WP_026584235	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. J33].	40.48	289	157	4	5	293	6	279	4e-65	218
rs:XP_004205400	Piso0_003646 [Millerozyma farinosa CBS 7064].	44.22	303	150	3	2	289	28	326	4e-65	230
rs:WP_021010769	5,10-methylene-tetrahydrofolate dehydrogenase [Agrococcus pavilionensis].	39.67	300	166	7	1	293	1	292	4e-65	218
rs:WP_002532729	5,10-methylene-tetrahydrofolate dehydrogenase [Propionibacterium acnes].	40.55	291	163	4	1	291	1	281	4e-65	218
rs:WP_018980770	5,10-methylene-tetrahydrofolate dehydrogenase [Saccharibacter floricola].	42.56	289	159	3	6	293	11	293	4e-65	218
sp:FOLD_PROAC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.55	291	163	4	1	291	1	281	4e-65	218
rs:WP_021917557	bifunctional protein FolD [Brachyspira sp. CAG:484].	44.06	286	140	6	4	286	3	271	4e-65	217
rs:WP_003663864	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus reuteri].	44.76	286	142	4	5	286	4	277	4e-65	217
rs:WP_014412755	5,10-methylene-tetrahydrofolate dehydrogenase [Rickettsia australis].	38.46	325	154	4	4	292	3	317	4e-65	219
rs:WP_034533504	methenyltetrahydrofolate cyclohydrolase [Lactobacillus kunkeei].	43.15	292	152	6	3	292	2	281	4e-65	217
sp:FOLD_RHIL3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.89	292	150	4	5	292	4	291	4e-65	218
rs:WP_027940859	5,10-methylene-tetrahydrofolate cyclohydrolase [Amycolatopsis taiwanensis].	39.86	291	160	3	1	291	1	276	4e-65	217
rs:WP_024100262	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodococcus pyridinivorans].	38.70	292	165	2	1	292	1	278	4e-65	217
rs:WP_026155212	methenyltetrahydrofolate cyclohydrolase [Paracoccus sp. N5].	43.21	287	155	3	6	292	1	279	4e-65	218
rs:XP_012153623	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Megachile rotundata].	42.81	292	159	4	5	292	9	296	4e-65	230
rs:WP_022034078	bifunctional protein FolD [Clostridium sp. CAG:710].	43.36	286	147	4	5	290	2	272	5e-65	217
rs:WP_037605612	methenyltetrahydrofolate cyclohydrolase [Streptacidiphilus rugosus].	41.10	292	161	4	1	292	1	281	5e-65	217
tr:L7MML7_9ACAR	SubName: Full=Putative methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:JAA64669.1}; Flags: Fragment;	44.29	289	148	5	3	286	8	288	5e-65	218
rs:XP_007590243	formate-tetrahydrofolate ligase [Colletotrichum fioriniae PJ7].	43.58	296	160	3	1	293	1	292	5e-65	230
rs:WP_014828223	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfosporosinus acidiphilus].	40.49	284	157	4	3	286	2	273	5e-65	217
rs:WP_007780025	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfosporosinus youngiae].	39.79	284	159	3	3	286	2	273	5e-65	217
rs:WP_031227022	5,10-methylene-tetrahydrofolate cyclohydrolase [Alcanivorax sp. P2S70].	39.46	294	163	3	1	293	1	280	5e-65	217
rs:XP_012285427	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Orussus abietinus].	43.15	292	158	4	5	292	9	296	5e-65	230
rs:WP_002544149	5,10-methylene-tetrahydrofolate dehydrogenase [Propionibacterium acnes].	40.55	291	163	4	1	291	1	281	5e-65	217
rs:XP_003700207	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Megachile rotundata].	42.81	292	159	4	5	292	20	307	5e-65	230
rs:WP_010542073	5,10-methylene-tetrahydrofolate dehydrogenase [Dietzia alimentaria].	43.10	290	146	6	1	286	1	275	5e-65	217
rs:WP_035403383	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus].	40.48	289	157	3	5	293	6	279	5e-65	217
rs:WP_018842085	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	39.51	286	163	5	1	286	1	276	5e-65	218
sp:FOLD_ORITI	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.16	287	160	3	5	290	4	285	5e-65	218
tr:D5P0T4_CORAM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.99	291	149	4	1	291	4	280	5e-65	217
rs:WP_014316428	bifunctional protein FolD [Corynebacterium diphtheriae].	42.57	296	151	6	1	292	1	281	5e-65	217
rs:WP_034664986	methenyltetrahydrofolate cyclohydrolase [Corynebacterium tuscaniense].	41.38	290	160	3	1	290	1	280	5e-65	217
rs:WP_031120017	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	40.07	292	165	3	1	292	1	282	5e-65	217
rs:WP_024460405	5,10-methylene-tetrahydrofolate cyclohydrolase [Marinimicrobium sp. LS-A18].	41.50	294	157	4	1	293	1	280	5e-65	217
rs:WP_014453083	tetrahydrofolate dehydrogenase [Caldisericum exile].	43.86	285	147	4	5	289	2	273	5e-65	217
tr:G2HFS6_PANTR	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:BAK62584.1};	53.78	225	97	3	73	291	5	228	5e-65	216
tr:A0A0C3PWS0_PISTI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIO13364.1};	43.20	294	157	4	2	289	3	292	6e-65	229
rs:XP_010759383	hypothetical protein PADG_04250 [Paracoccidioides brasiliensis Pb18].	44.03	293	157	3	1	290	100	388	6e-65	230
rs:WP_019875631	5,10-methylene-tetrahydrofolate dehydrogenase [Sporichthya polymorpha].	43.00	293	157	5	1	293	1	283	6e-65	217
rs:WP_016455504	hypothetical protein [Propionimicrobium lymphophilum].	42.31	286	154	4	1	286	1	275	6e-65	217
rs:WP_045641231	methenyltetrahydrofolate cyclohydrolase [Peptococcaceae bacterium BRH_c8a].	40.69	290	161	3	1	290	1	279	6e-65	217
rs:WP_003659896	5,10-methylene-tetrahydrofolate dehydrogenase [Moraxella catarrhalis].	41.03	290	158	5	3	291	2	279	6e-65	217
rs:WP_021809508	methylenetetrahydrofolate dehydrogenase [Leifsonia rubra].	41.75	297	160	6	1	291	1	290	6e-65	217
rs:WP_014490716	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobium japonicum].	42.91	289	159	2	1	289	1	283	6e-65	217
rs:XP_003745521	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Metaseiulus occidentalis].	42.42	297	162	4	3	294	2	294	6e-65	218
tr:S8DZW3_FOMPI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPS98516.1};	44.41	295	154	4	3	291	8	298	6e-65	229
rs:WP_047220987	5,10-methylene-tetrahydrofolate cyclohydrolase [Orientia tsutsugamushi].	42.16	287	160	3	5	290	4	285	6e-65	218
rs:WP_044586778	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. LTSPM299].	43.94	289	156	2	1	289	1	283	6e-65	217
rs:WP_016338999	methylenetetrahydrofolate dehydrogenase [Spiroplasma chrysopicola].	41.58	291	156	3	1	287	1	281	6e-65	217
rs:WP_043965711	methenyltetrahydrofolate cyclohydrolase [Micromonospora carbonacea].	41.10	292	166	4	1	292	1	286	6e-65	217
tr:A0A0C7MY68_9SACH	SubName: Full=LALA0S06e01090g1_1 {ECO:0000313|EMBL:CEP62675.1};	41.28	298	166	4	1	293	1	294	6e-65	229
tr:A0A024R652_HUMAN	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase, isoform CRA_a {ECO:0000313|EMBL:EAW80858.1};	42.57	296	161	4	3	293	4	295	6e-65	229
rs:WP_045825472	5,10-methylene-tetrahydrofolate cyclohydrolase [Teredinibacter sp. 991H.S.0a.06].	40.96	293	159	2	1	293	1	279	6e-65	217
gp:CS482708_1	Sequence 1 from Patent WO2007001259. [Homo sapiens]	42.57	296	161	4	3	293	4	295	6e-65	229
rs:WP_037740202	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. CNQ-525].	39.51	286	163	5	1	286	1	276	6e-65	218
rs:XP_007833359	C-1-tetrahydrofolate synthase [Pestalotiopsis fici W106-1].	41.10	292	165	3	1	289	1	288	6e-65	229
rs:WP_003168164	tetrahydrofolate dehydrogenase [Brevundimonas diminuta].	42.52	294	161	2	3	292	8	297	7e-65	218
rs:WP_045912337	5,10-methylene-tetrahydrofolate cyclohydrolase [Orientia tsutsugamushi].	42.16	287	160	3	5	290	4	285	7e-65	217
rs:WP_007598723	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobium sp. WSM1253].	42.91	289	159	2	1	289	1	283	7e-65	217
gp:BC050420_1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase [Homo sapiens]	42.57	296	161	4	3	293	4	295	7e-65	229
rs:WP_017930882	hypothetical protein [Robiginitomaculum antarcticum].	44.29	289	153	2	1	289	1	281	7e-65	217
rs:XP_624275	PREDICTED: bifunctional protein FolD 4, chloroplastic-like [Apis mellifera].	43.88	278	149	3	17	293	3	274	7e-65	216
tr:W6MTW1_9ASCO	SubName: Full=Genomic scaffold, Kuraishia_capsulata_scaffold_1 {ECO:0000313|EMBL:CDK25275.1};	38.72	297	173	4	1	292	1	293	7e-65	217
rs:WP_021801453	5,10-methylene-tetrahydrofolate dehydrogenase [Clostridium intestinale].	41.32	288	158	2	3	290	2	278	7e-65	216
rs:WP_027514920	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. WSM1417].	42.91	289	159	2	1	289	1	283	7e-65	217
rs:WP_019810388	5,10-methylene-tetrahydrofolate dehydrogenase [Saccharomonospora halophila].	41.72	290	154	3	1	290	1	275	7e-65	217
sp:FOLD2_SACEN	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.41	292	163	5	1	292	1	281	7e-65	217
sp:C1TC_HUMAN	RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3; Contains: RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed;	42.57	296	161	4	3	293	4	295	7e-65	229
rs:WP_034601008	methenyltetrahydrofolate cyclohydrolase [Desulfosporosinus sp. HMP52].	38.73	284	162	3	3	286	2	273	7e-65	217
rs:WP_020434476	bifunctional protein FolD [Clostridium sp. CAG:1000].	42.47	292	142	7	4	290	2	272	7e-65	217
rs:WP_016753432	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira kirschneri].	37.97	295	169	2	1	295	1	281	7e-65	217
rs:WP_015011699	bifunctional protein FolD [Propionibacterium acnes].	40.21	291	164	4	1	291	1	281	7e-65	217
rs:WP_013988159	methenyltetrahydrofolate cyclohydrolase [Sulfobacillus acidophilus].	38.33	287	166	2	5	291	2	277	7e-65	217
tr:A0A077R5C7_9BASI	SubName: Full=Probable MIS1-C1-tetrahydrofolate synthase, mitochondrial {ECO:0000313|EMBL:CDI54148.1};	44.97	298	153	5	3	293	11	304	7e-65	229
gpu:AP014685_3922	bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase [Bradyrhizobium diazoefficiens]	42.91	289	159	2	1	289	1	283	7e-65	217
tr:G8TYF1_SULAD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.33	287	166	2	5	291	6	281	7e-65	217
rs:XP_010877229	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Esox lucius].	44.63	298	156	4	1	293	1	294	7e-65	229
rs:WP_038304787	methenyltetrahydrofolate cyclohydrolase [bacterium YEK0313].	46.76	293	148	4	1	289	1	289	7e-65	217
rs:WP_027772138	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. CNQ329].	39.44	284	162	5	1	284	1	274	7e-65	217
rs:WP_013275612	methenyltetrahydrofolate cyclohydrolase [Thermosediminibacter oceani].	41.78	292	158	5	3	293	2	282	7e-65	217
rs:WP_007072903	5,10-methylene-tetrahydrofolate dehydrogenase [Micromonospora sp. ATCC 39149].	41.10	292	166	4	1	292	1	286	7e-65	217
rs:WP_046900649	methenyltetrahydrofolate cyclohydrolase [Gluconobacter oxydans].	43.45	290	158	2	1	290	8	291	8e-65	217
rs:WP_014061405	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces violaceusniger].	40.75	292	163	5	1	292	1	282	8e-65	217
rs:WP_045915942	5,10-methylene-tetrahydrofolate cyclohydrolase [Orientia tsutsugamushi].	42.16	287	160	3	5	290	4	285	8e-65	217
rs:WP_009483130	5,10-methylene-tetrahydrofolate dehydrogenase [Mobilicoccus pelagius].	41.44	292	158	5	1	292	1	279	8e-65	216
rs:XP_003831658	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Pan paniscus].	42.23	296	162	4	3	293	4	295	8e-65	229
rs:XP_007301078	FTHFS-domain-containing protein [Stereum hirsutum FP-91666 SS1].	44.26	296	155	4	2	291	41	332	8e-65	229
rs:WP_027018586	methenyltetrahydrofolate cyclohydrolase [Corynebacterium massiliense].	44.52	292	151	4	1	292	1	281	8e-65	217
rs:WP_005461541	5,10-methylene-tetrahydrofolate dehydrogenase [Saccharomonospora glauca].	40.27	293	164	4	1	293	1	282	8e-65	216
rs:WP_025085475	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus paralimentarius].	42.51	287	154	4	4	290	2	277	8e-65	216
rs:WP_028882463	bifunctional protein FolD [Teredinibacter turnerae].	40.61	293	160	2	1	293	1	279	8e-65	216
tr:K7ATQ6_PANTR	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase {ECO:0000313|EMBL:JAA11263.1};	42.23	296	162	4	3	293	4	295	8e-65	229
rs:WP_042407164	methenyltetrahydrofolate cyclohydrolase [Corynebacterium sp. JCB].	41.46	287	157	4	6	292	9	284	8e-65	217
rs:WP_038519404	5,10-methylene-tetrahydrofolate cyclohydrolase [Moraxella catarrhalis].	41.03	290	158	5	3	291	2	279	8e-65	216
rs:WP_028702880	methenyltetrahydrofolate cyclohydrolase [Propionibacterium jensenii].	41.55	296	158	6	1	291	1	286	8e-65	217
rs:WP_019620116	hypothetical protein [Amphritea japonica].	41.03	290	153	3	1	290	1	272	8e-65	216
rs:WP_008590439	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira licerasiae].	39.32	295	165	3	1	295	1	281	9e-65	216
rs:WP_028951574	5,10-methylene-tetrahydrofolate cyclohydrolase [Synechococcus sp. CC9616].	43.82	283	149	3	6	288	5	277	9e-65	217
rs:WP_037967105	hypothetical protein, partial [Streptomyces varsoviensis].	40.91	286	159	5	1	286	1	276	9e-65	217
rs:WP_019605374	5,10-methylene-tetrahydrofolate dehydrogenase [Teredinibacter turnerae].	40.61	293	160	2	1	293	1	279	9e-65	216
rs:XP_008871730	hypothetical protein H310_07972 [Aphanomyces invadans].	37.41	294	169	4	4	293	5	287	9e-65	217
tr:G8RM63_MYCRN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.72	290	159	4	1	290	1	280	9e-65	216
tr:G3QRA5_GORGO	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000005148};	42.23	296	162	4	3	293	4	295	9e-65	229
rs:WP_018354359	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium hassiacum].	43.06	288	148	6	6	290	3	277	9e-65	216
rs:XP_001386613	mitochondrial C1- tetrahydrofolate synthase precursor [Scheffersomyces stipitis CBS 6054].	42.35	307	154	4	1	289	31	332	9e-65	229
rs:WP_029367758	methenyltetrahydrofolate cyclohydrolase [Mycobacterium sp. UM_WWY].	43.71	286	150	4	1	286	1	275	9e-65	216
rs:WP_002515999	bifunctional protein FolD [Propionibacterium acnes].	40.55	291	163	4	1	291	1	281	9e-65	216
rs:WP_028822688	hypothetical protein, partial [Proteobacteria bacterium JGI 0000113-P07].	54.59	185	84	0	110	294	3	187	9e-65	213
rs:XP_012164280	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Bombus terrestris].	43.15	292	158	4	5	292	9	296	9e-65	229
rs:WP_030828630	methenyltetrahydrofolate cyclohydrolase [Streptomyces hygroscopicus].	41.96	286	156	5	1	286	1	276	9e-65	217
rs:WP_035148672	methenyltetrahydrofolate cyclohydrolase [Clostridium tetanomorphum].	41.43	280	153	2	6	285	5	273	9e-65	216
rs:WP_026396907	methenyltetrahydrofolate cyclohydrolase [Acetobacter nitrogenifigens].	43.84	292	158	2	4	295	33	318	9e-65	218
rs:XP_002548815	C-1-tetrahydrofolate synthase [Candida tropicalis MYA-3404].	41.22	296	165	4	1	291	1	292	1e-64	229
rs:WP_002525681	5,10-methylene-tetrahydrofolate dehydrogenase [Propionibacterium acnes].	40.55	291	163	4	1	291	1	281	1e-64	216
rs:WP_022700954	5,10-methylene-tetrahydrofolate dehydrogenase [Oceanicaulis alexandrii].	44.84	281	149	2	2	282	11	285	1e-64	217
rs:WP_028337626	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium elkanii].	43.16	285	152	3	1	285	1	275	1e-64	216
rs:WP_030728944	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-2890].	40.41	292	164	5	1	292	1	282	1e-64	216
tr:C1HC58_PARBA	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:EEH38622.2};	44.03	293	157	3	1	290	100	388	1e-64	229
rs:WP_027638368	methenyltetrahydrofolate cyclohydrolase [Clostridium cadaveris].	39.52	291	165	2	3	293	2	281	1e-64	216
rs:WP_003323632	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus alcalophilus].	40.75	292	158	4	1	292	1	277	1e-64	216
rs:WP_012846129	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus johnsonii].	42.11	285	152	4	4	286	3	276	1e-64	216
rs:WP_024352931	methenyltetrahydrofolate cyclohydrolase [Brevundimonas naejangsanensis].	42.86	294	160	2	3	292	8	297	1e-64	217
rs:WP_028885250	5,10-methylene-tetrahydrofolate cyclohydrolase [Teredinibacter turnerae].	40.96	293	159	2	1	293	1	279	1e-64	216
rs:WP_028244819	methenyltetrahydrofolate cyclohydrolase [Pseudoclavibacter soli].	41.08	297	166	5	1	293	1	292	1e-64	217
rs:WP_022894124	5,10-methylene-tetrahydrofolate dehydrogenase [Agromyces subbeticus].	40.67	300	165	6	1	294	1	293	1e-64	217
rs:WP_029105851	methenyltetrahydrofolate cyclohydrolase [Mycobacterium sp. 360MFTsu5.1].	42.66	293	157	4	1	293	1	282	1e-64	216
rs:WP_020554613	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces scabrisporus].	42.32	293	158	5	1	293	1	282	1e-64	216
rs:WP_006839536	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium lipophiloflavum].	43.82	283	140	6	6	284	9	276	1e-64	216
rs:XP_001792229	hypothetical protein SNOG_01593 [Phaeosphaeria nodorum SN15].	43.15	292	159	3	1	289	476	763	1e-64	231
rs:XP_003395757	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Bombus terrestris].	43.15	292	158	4	5	292	23	310	1e-64	229
rs:WP_014303009	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium diphtheriae].	42.23	296	152	6	1	292	1	281	1e-64	216
rs:WP_041949390	5,10-methylene-tetrahydrofolate cyclohydrolase [Turneriella parva].	40.55	291	152	4	8	291	2	278	1e-64	216
rs:XP_011878184	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Vollenhovia emeryi].	44.18	292	155	4	5	292	23	310	1e-64	229
tr:G3RRT3_GORGO	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000018507};	42.23	296	162	4	3	293	4	295	1e-64	229
rs:WP_003005517	tetrahydrofolate dehydrogenase [Leptospira weilii].	38.98	295	166	2	1	295	1	281	1e-64	216
tr:X0SKN6_9BACI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.21	291	159	4	1	291	1	276	1e-64	216
rs:WP_026756405	methenyltetrahydrofolate cyclohydrolase [Sediminimonas qiaohouensis].	46.33	300	147	3	1	292	1	294	1e-64	217
rs:WP_016404952	bifunctional protein FolD [Clostridium sp. CAG:1013].	54.55	209	85	3	82	290	1	199	1e-64	214
rs:WP_013461954	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Liberibacter solanacearum].	44.18	292	154	5	3	291	2	287	1e-64	217
tr:U7FLV4_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.46	294	163	3	1	293	20	299	1e-64	217
rs:WP_014901972	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfosporosinus meridiei].	38.73	284	162	3	3	286	2	273	1e-64	216
rs:XP_009426211	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Pan troglodytes].	42.23	296	162	4	3	293	60	351	1e-64	229
rs:WP_035306991	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. HMP27].	41.43	280	153	2	6	285	5	273	1e-64	216
tr:A0A0C4EEC8_MAGP6	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblFungi:MAPG_11099T0};	44.25	287	153	3	1	284	1	283	1e-64	229
rs:WP_028721299	methenyltetrahydrofolate cyclohydrolase, partial [Paracoccus yeei].	45.56	270	139	3	23	292	1	262	1e-64	216
rs:XP_011878185	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Vollenhovia emeryi].	44.18	292	155	4	5	292	9	296	1e-64	229
rs:WP_006904776	5,10-methylene-tetrahydrofolate dehydrogenase [Thermaerobacter subterraneus].	44.75	257	131	2	34	290	35	280	1e-64	217
rs:WP_039163727	methenyltetrahydrofolate cyclohydrolase, partial [Leisingera sp. ANG-M1].	47.49	259	129	3	34	292	2	253	1e-64	215
rs:WP_026374287	methenyltetrahydrofolate cyclohydrolase [Agrococcus lahaulensis].	40.27	298	167	7	1	293	1	292	1e-64	216
rs:XP_008036244	FTHFS-domain-containing protein [Trametes versicolor FP-101664 SS1].	45.08	295	152	4	3	291	8	298	1e-64	229
rs:WP_015469342	methylenetetrahydrofolate dehydrogenase [Bdellovibrio exovorus].	41.32	288	154	3	5	292	3	275	1e-64	216
rs:WP_010203651	5,10-methylene-tetrahydrofolate dehydrogenase [Salinibacterium sp. PAMC 21357].	41.08	297	162	6	1	291	1	290	1e-64	216
tr:E9DHY3_COCPS	SubName: Full=Formate-tetrahydrofolate ligase {ECO:0000313|EMBL:EFW14065.1};	42.91	296	162	3	1	293	1	292	1e-64	229
rs:WP_038604569	methenyltetrahydrofolate cyclohydrolase [Corynebacterium atypicum].	41.81	287	154	6	6	291	9	283	1e-64	216
rs:WP_019307612	hypothetical protein [SAR324 cluster bacterium SCGC AAA240-J09].	41.58	291	163	3	1	291	1	284	1e-64	216
tr:U5LEC5_9BACI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.18	289	155	4	5	293	40	313	1e-64	217
rs:WP_037820652	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Streptomyces sp. NRRL B-3229].	40.77	287	156	2	3	289	4	276	1e-64	216
rs:XP_011319220	C-1-tetrahydrofolate synthase [Fusarium graminearum PH-1].	43.25	289	157	3	1	286	1	285	1e-64	229
rs:WP_040421415	methenyltetrahydrofolate cyclohydrolase [Corynebacterium timonense].	40.96	293	162	4	1	293	4	285	1e-64	216
rs:WP_035570171	methenyltetrahydrofolate cyclohydrolase [Hyphomonas adhaerens].	48.26	259	126	4	34	289	30	283	1e-64	216
rs:XP_001270885	C1 tetrahydrofolate synthase, putative [Aspergillus clavatus NRRL 1].	43.69	293	158	3	1	290	1	289	1e-64	228
rs:WP_038049819	hypothetical protein [Thermoanaerobaculum aquaticum].	46.86	303	140	3	4	290	2	299	1e-64	216
rs:WP_023034955	FolD protein [Propionibacterium sp. KPL1844].	41.24	291	161	4	1	291	1	281	1e-64	216
rs:XP_001240508	formate-tetrahydrofolate ligase [Coccidioides immitis RS].	42.91	296	162	3	1	293	1	292	1e-64	228
rs:WP_015045585	5,10-methylene-tetrahydrofolate dehydrogenase [Simiduia agarivorans].	39.12	294	164	3	1	293	1	280	1e-64	216
rs:WP_005506812	5,10-methylene-tetrahydrofolate dehydrogenase [Rothia mucilaginosa].	42.91	296	154	7	4	292	3	290	1e-64	216
rs:WP_035153159	methenyltetrahydrofolate cyclohydrolase [Lactobacillus reuteri].	44.76	286	142	4	5	286	4	277	1e-64	216
tr:A0A067RJK1_ZOONE	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KDR19573.1};	44.41	295	156	4	2	292	10	300	1e-64	228
rs:WP_026792826	5,10-methylene-tetrahydrofolate cyclohydrolase [Pleomorphomonas oryzae].	39.80	294	162	3	1	293	1	280	1e-64	216
rs:XP_007764121	FTHFS-domain-containing protein [Coniophora puteana RWD-64-598 SS2].	42.57	296	160	4	2	291	7	298	1e-64	228
rs:WP_018274285	5,10-methylene-tetrahydrofolate dehydrogenase [Teredinibacter turnerae].	40.96	293	159	2	1	293	1	279	1e-64	216
rs:WP_044279187	TetR family transcriptional regulator [Candidatus Cloacimonas acidaminovorans].	39.10	289	170	2	4	292	3	285	1e-64	216
sp:FOLD_SACD2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.25	293	164	2	1	293	1	279	1e-64	216
rs:WP_047254170	methenyltetrahydrofolate cyclohydrolase [Corynebacterium testudinoris].	42.76	290	155	4	1	290	1	279	2e-64	216
tr:A0A061HZ51_CRIGR	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic-like protein {ECO:0000313|EMBL:ERE72753.1}; EC=1.5.1.5 {ECO:0000313|EMBL:ERE72753.1};	42.57	296	161	4	3	293	4	295	2e-64	228
rs:WP_018459745	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobium sp. WSM4349].	42.91	289	159	2	1	289	1	283	2e-64	216
rs:XP_011257510	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Camponotus floridanus].	44.18	292	155	4	5	292	21	308	2e-64	228
tr:Q2B9L0_9BACI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.18	289	155	4	5	293	45	318	2e-64	217
tr:B0VGJ7_CLOAI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.10	289	170	2	4	292	7	289	2e-64	216
rs:WP_024578643	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium].	43.01	286	153	3	1	286	1	276	2e-64	216
rs:WP_004566974	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium diphtheriae].	42.57	296	151	6	1	292	1	281	2e-64	216
tr:K1YJK0_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.15	292	149	6	1	292	1	275	2e-64	216
tr:A0A0B8REJ2_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.07	270	140	2	17	286	2	260	2e-64	215
rs:XP_003067987	C-1-tetrahydrofolate synthase, mitochondrial precursor, putative [Coccidioides posadasii C735 delta SOWgp].	42.91	296	162	3	1	293	1	292	2e-64	228
rs:WP_013951084	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Midichloria mitochondrii].	42.23	296	153	6	2	291	3	286	2e-64	216
rs:WP_007228071	5,10-methylene-tetrahydrofolate dehydrogenase [marine gamma proteobacterium HTCC2148].	40.14	294	161	3	1	293	1	280	2e-64	216
rs:WP_013640935	5,10-methylene-tetrahydrofolate dehydrogenase [Acidiphilium multivorum].	46.71	289	140	4	1	289	1	275	2e-64	216
rs:XP_011188046	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Bactrocera cucurbitae].	45.21	292	152	4	2	289	33	320	2e-64	228
rs:WP_012302120	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Desulforudis audaxviator].	41.61	286	155	3	5	290	4	277	2e-64	216
rs:WP_004894932	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus johnsonii].	42.61	284	150	4	5	286	4	276	2e-64	216
rs:WP_037158679	methenyltetrahydrofolate cyclohydrolase [Rhizobium sp. YS-1r].	44.75	295	153	5	3	292	2	291	2e-64	216
tr:I1KFP4_SOYBN	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:GLYMA06G47350.1};	41.05	285	161	3	11	293	51	330	2e-64	217
rs:WP_028426732	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. TAA040].	40.91	286	159	5	1	286	1	276	2e-64	216
tr:X1NFL0_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S06061 {ECO:0000313|EMBL:GAI28976.1}; Flags: Fragment;	42.91	261	135	3	33	290	5	254	2e-64	215
rs:WP_037209704	methenyltetrahydrofolate cyclohydrolase [Rhodovulum sp. NI22].	44.71	293	157	2	1	292	1	289	2e-64	216
rs:WP_016665057	MULTISPECIES: hypothetical protein [Dermabacter].	42.91	296	161	5	1	292	1	292	2e-64	216
tr:X0XZY6_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S26167 {ECO:0000313|EMBL:GAG40727.1}; Flags: Fragment;	43.25	252	142	1	11	262	2	252	2e-64	215
rs:WP_030112699	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	40.91	286	159	5	1	286	1	276	2e-64	216
rs:WP_030331464	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL B-1381].	40.91	286	159	5	1	286	1	276	2e-64	216
rs:WP_022791308	5,10-methylene-tetrahydrofolate dehydrogenase [Weissella halotolerans].	43.34	293	150	6	3	290	2	283	2e-64	216
rs:XP_011452618	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Crassostrea gigas].	44.26	296	156	4	3	293	2	293	2e-64	228
sp:FOLD_MYCSJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.07	290	158	4	1	290	4	283	2e-64	216
sp:FOLD_CLOP1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.64	281	152	3	4	284	3	271	2e-64	215
rs:WP_006062604	tetrahydrofolate dehydrogenase [Corynebacterium durum].	42.03	295	152	6	1	291	1	280	2e-64	216
rs:WP_035244188	5,10-methylene-tetrahydrofolate cyclohydrolase [Alcanivorax jadensis].	40.14	294	161	4	1	293	1	280	2e-64	216
sp:FOLD_CORGB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.61	291	156	4	1	291	1	280	2e-64	216
sp:FOLD_TERTT	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.27	293	161	2	1	293	1	279	2e-64	216
rs:WP_045913308	5,10-methylene-tetrahydrofolate cyclohydrolase [Orientia tsutsugamushi].	41.81	287	161	3	5	290	4	285	2e-64	216
rs:WP_005508973	5,10-methylene-tetrahydrofolate dehydrogenase [Rothia mucilaginosa].	42.57	296	155	7	4	292	3	290	2e-64	216
rs:WP_013170472	5,10-methylene-tetrahydrofolate dehydrogenase [Arcanobacterium haemolyticum].	41.13	282	156	6	6	286	7	279	2e-64	216
rs:WP_041944715	methenyltetrahydrofolate cyclohydrolase [Tsukamurella paurometabola].	40.74	297	165	5	1	297	1	286	2e-64	216
rs:XP_004065509	PREDICTED: LOW QUALITY PROTEIN: c-1-tetrahydrofolate synthase, cytoplasmic [Gorilla gorilla gorilla].	42.23	296	162	4	3	293	60	351	2e-64	228
rs:XP_008324163	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Cynoglossus semilaevis].	44.63	298	156	4	1	293	1	294	2e-64	228
sp:FOLD_CORDI	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.23	296	152	6	1	292	1	281	2e-64	215
sp:FOLD_NITHX	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.21	289	161	2	1	289	1	283	2e-64	216
rs:WP_003458738	bifunctional protein FolD [Clostridium perfringens].	41.64	281	152	3	4	284	3	271	2e-64	215
tr:D2NPC1_ROTMD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.57	296	155	7	4	292	8	295	2e-64	216
rs:WP_024110425	tetrahydrofolate dehydrogenase [Propionimicrobium sp. BV2F7].	41.96	286	155	4	1	286	1	275	2e-64	215
rs:XP_003499357	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Cricetulus griseus].	42.57	296	161	4	3	293	4	295	2e-64	228
rs:WP_023019043	MULTISPECIES: FolD protein [Corynebacterium].	42.41	290	156	4	1	290	4	282	2e-64	216
rs:XP_002490773	C-1-tetrahydrofolate synthase, mitochondrial [Komagataella pastoris GS115].	43.64	291	157	3	3	290	38	324	2e-64	228
tr:M3JUC0_CANMX	SubName: Full=C-1-tetrahydrofolate synthase, mitochondrial {ECO:0000313|EMBL:EMG45964.1}; Flags: Fragment;	44.04	302	152	4	1	289	24	321	2e-64	228
rs:WP_040487598	methenyltetrahydrofolate cyclohydrolase [Fodinicurvata sediminis].	38.33	287	170	3	4	290	7	286	2e-64	216
rs:WP_005485007	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces bottropensis].	40.96	293	154	3	1	291	1	276	2e-64	216
rs:WP_034648978	methenyltetrahydrofolate cyclohydrolase [Corynebacterium vitaeruminis].	42.86	294	149	6	1	290	4	282	2e-64	216
rs:WP_037481350	methenyltetrahydrofolate cyclohydrolase [Sphingobium sp. KK22].	43.49	292	157	4	1	292	1	284	2e-64	216
rs:NP_005947	C-1-tetrahydrofolate synthase, cytoplasmic [Homo sapiens].	42.23	296	162	4	3	293	4	295	2e-64	228
rs:WP_040962669	methenyltetrahydrofolate cyclohydrolase [Sinorhizobium fredii].	43.75	288	151	5	6	291	10	288	2e-64	216
rs:WP_019310213	5,10-methylene-tetrahydrofolate dehydrogenase [Kocuria rhizophila].	41.08	297	166	6	1	293	1	292	2e-64	216
rs:WP_003468996	bifunctional protein FolD [Clostridium perfringens].	41.64	281	152	3	4	284	3	271	2e-64	215
rs:WP_039673893	methenyltetrahydrofolate cyclohydrolase [Corynebacterium minutissimum].	42.37	295	151	6	1	291	1	280	2e-64	215
rs:XP_010771467	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Notothenia coriiceps].	44.63	298	156	4	1	293	1	294	2e-64	228
rs:WP_003451122	bifunctional protein FolD [Clostridium perfringens].	41.64	281	152	3	4	284	3	271	2e-64	215
rs:WP_029121025	methenyltetrahydrofolate cyclohydrolase [Mycobacterium sp. UNC410CL29Cvi84].	42.66	293	157	4	1	293	1	282	2e-64	215
rs:WP_023599450	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus johnsonii].	43.25	289	152	4	4	292	3	279	2e-64	215
rs:WP_014525380	hypothetical protein [Corynebacterium ulcerans].	43.88	294	146	6	1	290	1	279	2e-64	215
rs:XP_003681949	hypothetical protein TDEL_0E04950 [Torulaspora delbrueckii].	44.15	299	157	4	1	293	1	295	3e-64	228
rs:WP_035057713	methenyltetrahydrofolate cyclohydrolase [Cellulomonas bogoriensis].	42.76	297	157	6	3	293	7	296	3e-64	216
rs:WP_017538606	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis].	43.30	291	154	5	1	291	1	280	3e-64	215
rs:WP_035129366	hypothetical protein [Clostridium sulfidigenes].	42.01	288	155	3	6	293	5	280	3e-64	215
tr:V5ESN1_PSEBG	SubName: Full=C1-tetrahydrofolate synthase {ECO:0000313|EMBL:EST04939.1};	44.30	298	155	5	3	293	11	304	3e-64	228
rs:XP_003962475	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Takifugu rubripes].	44.30	298	157	4	1	293	1	294	3e-64	228
rs:WP_013910882	hypothetical protein [Corynebacterium ulcerans].	43.88	294	146	6	1	290	1	279	3e-64	215
rs:WP_036523922	methenyltetrahydrofolate cyclohydrolase [Novosphingobium resinovorum].	41.87	289	161	3	3	291	2	283	3e-64	215
rs:WP_046538331	methenyltetrahydrofolate cyclohydrolase [Clostridiales bacterium PH28_bin88].	41.58	291	159	3	3	293	2	281	3e-64	215
rs:WP_020934029	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium maris].	41.44	292	157	4	1	292	1	278	3e-64	215
rs:XP_004612420	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Sorex araneus].	42.32	293	160	4	3	290	4	292	3e-64	228
rs:WP_008521604	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Jonquetella].	41.24	291	159	4	1	291	1	279	3e-64	215
tr:A0A096PFN0_9HYPO	SubName: Full=WGS project CBMG000000000 data, contig CS5907-c001403 {ECO:0000313|EMBL:CEG03581.1};	41.87	289	161	3	1	286	1	285	3e-64	228
tr:M8AI22_TRIUA	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:EMS64570.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:TRIUR3_17732-P1};	39.63	323	158	3	2	291	87	405	3e-64	219
rs:WP_045916820	5,10-methylene-tetrahydrofolate cyclohydrolase [Orientia tsutsugamushi].	41.81	287	161	3	5	290	4	285	3e-64	216
tr:K0T973_THAOC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJK75248.1};	40.32	310	162	5	1	292	1	305	3e-64	216
rs:WP_027566323	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. URHA0013].	42.56	289	160	2	1	289	1	283	3e-64	215
rs:XP_004844811	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Heterocephalus glaber].	43.14	299	121	3	3	295	39	294	3e-64	216
rs:WP_027749371	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. CNH287].	40.75	292	163	5	1	292	1	282	3e-64	215
tr:K1XXN9_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.64	291	144	7	5	293	2	274	3e-64	215
rs:WP_026370449	hypothetical protein [bacterium JKG1].	41.18	289	160	2	5	293	4	282	3e-64	215
rs:WP_046696671	5,10-methylene-tetrahydrofolate cyclohydrolase [Moraxella bovoculi].	39.58	288	163	4	3	290	2	278	3e-64	215
rs:WP_032503911	methenyltetrahydrofolate cyclohydrolase [Propionibacterium acnes].	40.55	291	163	4	1	291	1	281	3e-64	215
tr:A0A0B7K7I4_BIOOC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CEO53139.1};	42.86	294	161	3	1	291	1	290	3e-64	228
rs:XP_006458125	hypothetical protein AGABI2DRAFT_183212 [Agaricus bisporus var. bisporus H97].	44.04	302	154	6	1	291	1	298	3e-64	228
sp:FOLD_RHILT	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.55	292	151	4	5	292	4	291	3e-64	215
rs:WP_037672725	methenyltetrahydrofolate cyclohydrolase [Streptomyces griseus].	41.78	292	160	4	1	292	1	282	3e-64	215
rs:WP_027330871	5,10-methylene-tetrahydrofolate cyclohydrolase [Marinimicrobium agarilyticum].	40.48	294	161	3	1	293	1	281	3e-64	215
rs:WP_003675667	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus reuteri].	44.41	286	143	4	5	286	4	277	3e-64	215
rs:WP_043362188	methenyltetrahydrofolate cyclohydrolase, partial [Corynebacterium bovis].	44.03	293	139	7	6	291	1	275	3e-64	215
rs:WP_027533229	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. WSM3983].	42.56	289	160	2	1	289	1	283	4e-64	215
rs:WP_035187661	methenyltetrahydrofolate cyclohydrolase [Acidiphilium sp. JA12-A1].	46.37	289	141	4	1	289	1	275	4e-64	215
rs:WP_004456710	tetrahydrofolate dehydrogenase [Clostridium perfringens].	41.64	281	152	3	4	284	3	271	4e-64	214
rs:WP_010373089	5,10-methylene-tetrahydrofolate dehydrogenase [Weissella cibaria].	43.25	289	147	7	3	286	2	278	4e-64	215
rs:XP_011107300	hypothetical protein H072_1308 [Dactylellina haptotyla CBS 200.50].	41.50	294	165	3	1	291	93	382	4e-64	228
tr:A0A0A0C3P1_9CELL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.76	297	157	6	3	293	48	337	4e-64	217
rs:WP_026928319	methenyltetrahydrofolate cyclohydrolase [Granulicoccus phenolivorans].	40.56	286	160	4	1	286	1	276	4e-64	215
tr:I4B865_TURPD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.55	291	152	4	8	291	25	301	4e-64	216
rs:XP_001400370	hypothetical protein ANI_1_3132024 [Aspergillus niger CBS 513.88].	43.00	293	160	3	1	290	1	289	4e-64	223
tr:F5H2F4_HUMAN	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSP00000438588};	42.23	296	162	4	3	293	60	351	4e-64	228
rs:WP_040813020	5,10-methylene-tetrahydrofolate cyclohydrolase [marine gamma proteobacterium HTCC2080].	39.12	294	164	3	1	293	1	280	4e-64	215
rs:WP_026159256	methenyltetrahydrofolate cyclohydrolase [Corynebacterium doosanense].	40.69	290	161	4	1	290	1	279	4e-64	215
tr:A0A0B7FU49_THACB	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase {ECO:0000313|EMBL:CEL59697.1}; EC=6.3.4.3 {ECO:0000313|EMBL:CEL59697.1};	41.89	296	160	4	3	290	29	320	4e-64	228
rs:WP_014523812	hypothetical protein [Corynebacterium pseudotuberculosis].	45.24	294	141	7	1	290	1	278	4e-64	214
rs:WP_042529495	methenyltetrahydrofolate cyclohydrolase [Corynebacterium singulare].	42.37	295	151	6	1	291	1	280	4e-64	215
rs:WP_031282328	methenyltetrahydrofolate cyclohydrolase [Kocuria sp. UCD-OTCP].	41.89	296	161	7	1	291	1	290	4e-64	215
rs:WP_015785539	5,10-methylene-tetrahydrofolate dehydrogenase [Saccharomonospora viridis].	42.41	290	152	3	1	290	1	275	4e-64	215
rs:WP_038551298	methenyltetrahydrofolate cyclohydrolase [Corynebacterium glyciniphilum].	43.49	292	146	6	6	293	14	290	4e-64	215
rs:WP_018197721	MULTISPECIES: hypothetical protein [unclassified Cloacimonetes].	39.10	289	170	2	4	292	7	289	4e-64	216
rs:WP_027283023	methenyltetrahydrofolate cyclohydrolase [Roseomonas gilardii].	46.09	256	128	2	34	289	30	275	4e-64	214
rs:XP_009394802	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X2 [Musa acuminata subsp. malaccensis].	43.51	262	142	2	32	291	7	264	4e-64	214
rs:WP_014301483	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium diphtheriae].	42.23	296	152	6	1	292	1	281	4e-64	214
tr:A0A084BMJ8_ASPFM	SubName: Full=C1 tetrahydrofolate synthase {ECO:0000313|EMBL:KEY78777.1};	43.34	293	159	3	1	290	80	368	4e-64	228
sp:FOLD_CLOPS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.64	281	152	3	4	284	3	271	4e-64	214
sp:FOLD_CLOPE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.64	281	152	3	4	284	3	271	4e-64	214
rs:WP_021198834	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Microbacterium].	42.62	298	160	7	1	293	1	292	4e-64	215
tr:X5E7A8_9CORY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.49	292	146	6	6	293	17	293	4e-64	215
rs:WP_018645115	5,10-methylene-tetrahydrofolate dehydrogenase [Bradyrhizobium japonicum].	42.56	289	160	2	1	289	1	283	5e-64	215
rs:XP_006617358	PREDICTED: LOW QUALITY PROTEIN: c-1-tetrahydrofolate synthase, cytoplasmic-like [Apis dorsata].	43.49	292	157	4	5	292	9	296	5e-64	227
rs:WP_043707617	methenyltetrahydrofolate cyclohydrolase [Weissella cibaria].	43.25	289	147	7	3	286	2	278	5e-64	215
rs:WP_040967037	bifunctional protein FolD [Corynebacterium glutamicum].	42.27	291	157	4	1	291	1	280	5e-64	214
rs:WP_036672298	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. HGF5].	39.32	295	162	5	1	293	1	280	5e-64	214
rs:WP_024876237	methenyltetrahydrofolate cyclohydrolase [Saccharomonospora sp. CNQ490].	40.07	292	164	4	1	292	1	281	5e-64	214
rs:XP_009254998	hypothetical protein FPSE_03604 [Fusarium pseudograminearum CS3096].	42.91	289	158	3	1	286	1	285	5e-64	227
rs:WP_043941465	methenyltetrahydrofolate cyclohydrolase [Weissella cibaria].	43.25	289	147	7	3	286	2	278	5e-64	215
tr:A0A0D0CQR3_9AGAR	SubName: Full=Unplaced genomic scaffold GYMLUscaffold_41, whole genome shotgun sequence {ECO:0000313|EMBL:KIK57823.1};	43.58	296	157	4	2	291	4	295	5e-64	227
tr:A0Z909_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.12	294	164	3	1	293	5	284	5e-64	214
rs:WP_036925582	methenyltetrahydrofolate cyclohydrolase, partial [Propionibacterium thoenii].	41.58	291	160	5	1	291	1	281	5e-64	214
rs:WP_020038017	5,10-methylene-tetrahydrofolate dehydrogenase [gamma proteobacterium SCGC AAA168-P09].	40.21	291	159	4	1	291	1	276	5e-64	214
rs:XP_007269720	FTHFS-domain-containing protein [Fomitiporia mediterranea MF3/22].	43.58	296	157	4	2	291	7	298	5e-64	227
rs:WP_019252443	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus reuteri].	44.41	286	143	4	5	286	4	277	5e-64	214
rs:YP_002049402	Methylenetetrahydrofolate dehydrogenase (NADP+) [Paulinella chromatophora].	42.81	285	156	2	6	287	5	285	5e-64	215
tr:A0A0D2XMK8_FUSO4	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblFungi:FOXG_05185P0};	42.91	289	158	3	1	286	1	285	5e-64	227
rs:WP_026864401	methenyltetrahydrofolate cyclohydrolase [Intrasporangiaceae bacterium URHB0013].	41.30	293	159	5	1	293	1	280	6e-64	214
rs:WP_030300529	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-6131].	42.96	291	155	5	1	291	1	280	6e-64	214
rs:XP_002290493	5, 10-methylenetetrahydrofolate dehydrogenase [Thalassiosira pseudonana CCMP1335].	39.12	317	161	6	1	292	1	310	6e-64	215
rs:XP_010981181	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Camelus dromedarius].	55.19	212	88	3	89	294	2	212	6e-64	212
sp:FOLD_LEIXX	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.10	297	160	6	1	293	1	292	6e-64	215
rs:WP_034441428	methenyltetrahydrofolate cyclohydrolase [Candidatus Liberibacter solanacearum].	43.84	292	155	5	3	291	2	287	6e-64	215
rs:XP_001208969	C-1-tetrahydrofolate synthase, mitochondrial precursor [Aspergillus terreus NIH2624].	43.34	293	159	3	1	290	1	289	6e-64	227
tr:T1PFK0_MUSDO	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:AFP61312.1};	48.76	242	117	3	56	291	2	242	6e-64	213
rs:WP_047261263	methenyltetrahydrofolate cyclohydrolase [Corynebacterium mustelae].	41.92	291	158	4	1	291	1	280	6e-64	214
rs:WP_003854648	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium glutamicum].	42.61	291	156	4	1	291	1	280	6e-64	214
rs:WP_043472108	methenyltetrahydrofolate cyclohydrolase [Streptomyces fradiae].	39.04	292	168	5	1	292	1	282	6e-64	214
sp:FOLD1_LACJO	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.96	286	153	4	3	286	2	276	6e-64	214
rs:WP_017181841	5,10-methylene-tetrahydrofolate dehydrogenase [Sphingobium xenophagum].	43.45	290	157	3	3	292	2	284	6e-64	214
rs:WP_030263650	methenyltetrahydrofolate cyclohydrolase [Streptomyces violens].	40.75	292	162	5	1	292	1	281	6e-64	214
rs:WP_009760110	5,10-methylene-tetrahydrofolate dehydrogenase [Roseibium sp. TrichSKD4].	41.44	292	167	1	1	292	1	288	6e-64	215
rs:WP_045915567	5,10-methylene-tetrahydrofolate cyclohydrolase [Orientia tsutsugamushi].	41.81	287	161	3	5	290	4	285	6e-64	215
rs:XP_010032802	PREDICTED: bifunctional protein FolD 2-like isoform X2 [Eucalyptus grandis].	39.46	294	172	2	2	293	66	355	6e-64	216
rs:WP_043711140	methenyltetrahydrofolate cyclohydrolase [Weissella cibaria].	43.40	288	146	7	3	285	2	277	6e-64	214
tr:A0A014QWW7_9HYPO	SubName: Full=Tetrahydrofolate synthase {ECO:0000313|EMBL:EXU98799.1};	42.27	291	161	3	1	288	1	287	7e-64	226
rs:WP_041302818	methenyltetrahydrofolate cyclohydrolase [Mycobacterium rhodesiae].	41.38	290	160	4	1	290	3	282	7e-64	214
rs:XP_007881353	hypothetical protein PFL1_05629 [Pseudozyma flocculosa PF-1].	44.30	298	155	5	3	293	11	304	7e-64	227
rs:XP_001436995	hypothetical protein [Paramecium tetraurelia strain d4-2].	45.00	260	126	6	34	291	24	268	7e-64	214
rs:WP_003673163	5,10-methylene-tetrahydrofolate dehydrogenase [Moraxella catarrhalis].	40.69	290	159	5	3	291	2	279	7e-64	214
rs:XP_004182393	hypothetical protein TBLA_0I02160 [Tetrapisispora blattae CBS 6284].	44.14	290	155	3	4	290	29	314	7e-64	227
rs:WP_034714307	methenyltetrahydrofolate cyclohydrolase [Intrasporangium chromatireducens].	40.77	287	157	5	1	287	1	274	7e-64	214
tr:B7Z809_HUMAN	SubName: Full=cDNA FLJ56016, highly similar to C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:BAH13795.1};	41.89	296	163	4	3	293	60	351	7e-64	227
tr:M2QMN5_CERS8	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EMD38308.1};	43.24	296	158	4	2	291	8	299	7e-64	226
rs:WP_022297240	bifunctional protein FolD [Clostridium sp. CAG:465].	39.02	287	163	3	5	291	8	282	7e-64	214
rs:WP_030846185	methenyltetrahydrofolate cyclohydrolase [Streptomyces griseus].	40.56	286	160	5	1	286	1	276	7e-64	214
rs:WP_040345229	methenyltetrahydrofolate cyclohydrolase [Brevundimonas diminuta].	42.52	294	161	2	3	292	8	297	7e-64	215
rs:WP_009332509	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus sp. 2_A_57_CT2].	39.72	287	158	3	5	291	6	277	7e-64	214
tr:B0XYC7_ASPFC	SubName: Full=C1 tetrahydrofolate synthase, putative {ECO:0000313|EMBL:EDP52873.1};	43.34	293	159	3	1	290	1	289	7e-64	226
rs:WP_007423796	bifunctional protein FolD, partial [Acidiphilium sp. PM].	48.05	256	123	2	34	289	1	246	7e-64	213
rs:XP_004351243	methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase [Dictyostelium fasciculatum].	41.60	262	146	3	34	289	23	283	7e-64	215
rs:WP_003929299	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium vaccae].	42.07	290	158	4	1	290	1	280	8e-64	214
rs:WP_012845917	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus johnsonii].	42.56	289	154	3	4	292	3	279	8e-64	214
rs:WP_003672226	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus reuteri].	44.06	286	144	4	5	286	4	277	8e-64	214
rs:XP_754750	C1 tetrahydrofolate synthase [Aspergillus fumigatus Af293].	43.34	293	159	3	1	290	1	289	8e-64	226
rs:XP_001263575	C1 tetrahydrofolate synthase, putative [Neosartorya fischeri NRRL 181].	43.34	293	159	3	1	290	1	289	8e-64	226
sp:FOLD_ACICJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.37	289	141	4	1	289	1	275	8e-64	214
rs:XP_011307448	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Fopius arisanus].	42.12	292	161	4	5	292	9	296	8e-64	226
tr:A0A067PBP7_PLEOS	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDQ33296.1};	43.73	295	156	4	3	291	12	302	8e-64	226
rs:WP_013625057	5,10-methylene-tetrahydrofolate dehydrogenase [Syntrophobotulus glycolicus].	41.90	284	153	3	3	286	2	273	8e-64	214
rs:WP_045249462	methenyltetrahydrofolate cyclohydrolase [Microbacterium azadirachtae].	40.74	297	167	6	1	293	1	292	8e-64	214
rs:XP_010653087	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X2 [Vitis vinifera].	43.35	263	143	2	32	292	7	265	8e-64	213
rs:WP_035754909	methenyltetrahydrofolate cyclohydrolase [Arthrobacter albus].	39.80	299	167	6	1	293	1	292	8e-64	214
rs:XP_011312222	PREDICTED: uncharacterized protein LOC105272042 [Fopius arisanus].	45.73	293	145	4	3	286	788	1075	8e-64	229
rs:WP_035230887	5,10-methylene-tetrahydrofolate cyclohydrolase [Alcanivorax sp. 19-m-6].	38.78	294	165	4	1	293	1	280	9e-64	214
rs:WP_046752851	methenyltetrahydrofolate cyclohydrolase [Mycobacterium elephantis].	43.01	286	153	4	1	286	4	279	9e-64	214
tr:A0A0D9PV75_METAN	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:KJK90222.1};	42.27	291	161	3	1	288	154	440	9e-64	227
rs:XP_010032801	PREDICTED: bifunctional protein FolD 2-like isoform X1 [Eucalyptus grandis].	39.46	294	172	2	2	293	67	356	9e-64	216
rs:WP_015400054	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium halotolerans].	41.96	286	155	4	1	286	1	275	9e-64	214
rs:WP_022889843	5,10-methylene-tetrahydrofolate dehydrogenase [Agromyces italicus].	41.36	295	160	6	1	289	1	288	9e-64	214
rs:WP_016458871	FolD protein [Corynebacterium pyruviciproducens].	41.78	292	159	4	1	292	1	281	9e-64	214
tr:K1RIC5_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKC43429.1}; Flags: Fragment;	47.88	236	118	2	3	238	2	232	9e-64	212
rs:WP_010410566	5,10-methylene-tetrahydrofolate dehydrogenase [Leptospira inadai].	39.32	295	165	2	1	295	1	281	9e-64	214
rs:WP_026033077	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Roseomonas].	44.29	289	147	3	1	289	1	275	1e-63	214
rs:WP_043496927	methenyltetrahydrofolate cyclohydrolase [Georgenia sp. SUBG003].	39.53	296	170	5	1	292	1	291	1e-63	214
rs:WP_010119900	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium nuruki].	41.24	291	160	4	1	291	1	280	1e-63	214
rs:WP_008735406	5,10-methylene-tetrahydrofolate dehydrogenase [Alcanivorax pacificus].	39.46	294	163	3	1	293	1	280	1e-63	214
rs:XP_011329732	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Cerapachys biroi].	42.81	292	159	4	5	292	9	296	1e-63	226
rs:WP_013615173	5,10-methylene-tetrahydrofolate dehydrogenase [Deinococcus proteolyticus].	45.52	290	146	5	1	290	1	278	1e-63	214
tr:A0A0A1WE49_BACCU	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:JAC97273.1};	44.86	292	153	4	2	289	33	320	1e-63	226
tr:W9PNP0_FUSOX	SubName: Full=Formate-tetrahydrofolate ligase {ECO:0000313|EMBL:EXA44656.1};	42.91	289	158	3	1	286	170	454	1e-63	227
tr:A0A060Q7Z0_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.14	290	155	3	3	291	13	296	1e-63	214
rs:WP_044509960	methenyltetrahydrofolate cyclohydrolase [Mycobacterium simiae].	41.24	291	160	4	1	291	1	280	1e-63	214
tr:X0JL46_FUSOX	SubName: Full=Formate-tetrahydrofolate ligase {ECO:0000313|EMBL:EXM01913.1};	42.91	289	158	3	1	286	170	454	1e-63	227
tr:X0I8A2_FUSOX	SubName: Full=Formate-tetrahydrofolate ligase {ECO:0000313|EMBL:EXL84982.1};	42.91	289	158	3	1	286	170	454	1e-63	227
rs:WP_021351876	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium pseudodiphtheriticum].	42.07	290	157	4	1	290	4	282	1e-63	214
rs:XP_010032806	PREDICTED: bifunctional protein FolD 2-like isoform X1 [Eucalyptus grandis].	37.66	308	172	3	2	293	135	438	1e-63	218
rs:XP_012183864	predicted protein [Fibroporia radiculosa].	42.57	296	160	4	2	291	11	302	1e-63	226
tr:U1QVR2_9EURY	SubName: Full=5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:ERH11408.1};	43.75	288	158	2	4	291	3	286	1e-63	223
rs:XP_010032807	PREDICTED: bifunctional protein FolD 2-like isoform X2 [Eucalyptus grandis].	37.66	308	172	3	2	293	134	437	1e-63	218
rs:WP_043562150	methenyltetrahydrofolate cyclohydrolase [Saccharibacter sp. AM169].	44.14	290	155	3	3	291	15	298	1e-63	214
tr:X0M4D8_FUSOX	SubName: Full=Formate-tetrahydrofolate ligase {ECO:0000313|EMBL:EXM33008.1};	42.91	289	158	3	1	286	170	454	1e-63	227
rs:XP_007361315	C-1-tetrahydrofolate synthase [Dichomitus squalens LYAD-421 SS1].	42.57	296	160	4	2	291	4	295	1e-63	226
tr:L7J1G4_MAGOP	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:ELQ61988.1};	42.81	292	160	3	1	289	123	410	1e-63	227
rs:WP_042733893	methenyltetrahydrofolate cyclohydrolase [Rathayibacter toxicus].	40.13	299	167	6	1	293	1	293	1e-63	214
rs:XP_003717930	C-1-tetrahydrofolate synthase [Magnaporthe oryzae 70-15].	42.81	292	160	3	1	289	135	422	1e-63	227
tr:W5XYE3_9CORY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.52	294	150	6	1	290	1	279	1e-63	214
rs:XP_006396260	hypothetical protein EUTSA_v10029292mg [Eutrema salsugineum].	41.33	300	159	3	5	291	64	359	1e-63	216
tr:K7KYI8_SOYBN	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:GLYMA06G47350.2};	42.75	269	147	3	27	293	2	265	1e-63	213
tr:W9IDB8_FUSOX	SubName: Full=Formate-tetrahydrofolate ligase {ECO:0000313|EMBL:EWY90476.1};	42.91	289	158	3	1	286	170	454	1e-63	227
tr:A5MC90_STREE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.35	222	98	3	72	293	5	216	1e-63	211
rs:WP_019632411	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomadura atramentaria].	41.84	282	153	4	1	282	1	271	1e-63	213
rs:WP_014431510	bifunctional protein FolD [Caldilinea aerophila].	38.78	294	168	3	1	293	1	283	1e-63	214
tr:X0A620_FUSOX	SubName: Full=Formate-tetrahydrofolate ligase {ECO:0000313|EMBL:EXK39120.1};	42.91	289	158	3	1	286	170	454	1e-63	227
rs:WP_022108862	bifunctional protein FolD [Clostridium sp. CAG:533].	41.26	286	150	5	5	290	2	269	1e-63	213
sp:FOLD_LACRD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	44.41	286	143	4	5	286	4	277	1e-63	214
rs:WP_038595189	methenyltetrahydrofolate cyclohydrolase [Corynebacterium vitaeruminis].	42.52	294	150	6	1	290	4	282	1e-63	214
tr:F3MA87_9BACL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.32	295	162	5	1	293	31	310	1e-63	214
rs:WP_009836256	5,10-methylene-tetrahydrofolate dehydrogenase [Marinomonas sp. MED121].	38.23	293	167	2	1	293	1	279	1e-63	213
rs:WP_006244248	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium tusciae].	41.30	293	162	4	1	293	1	283	1e-63	214
rs:WP_039100891	methenyltetrahydrofolate cyclohydrolase [Kocuria rhizophila].	41.08	297	166	6	1	293	1	292	1e-63	214
rs:XP_003598120	FolD bifunctional protein [Medicago truncatula].	39.12	294	172	3	2	293	72	360	1e-63	216
rs:WP_026168048	methenyltetrahydrofolate cyclohydrolase [Corynebacterium propinquum].	42.07	290	157	4	1	290	1	279	1e-63	213
tr:M1VVE3_CLAP2	SubName: Full=Probable C1-tetrahydrofolate synthase {ECO:0000313|EMBL:CCE29372.1};	42.66	293	157	5	1	288	1	287	1e-63	226
rs:WP_045481578	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. TS-2].	40.42	287	156	4	5	291	22	293	1e-63	214
sp:C1TC_PONAB	RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3; Contains: RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed;	41.55	296	164	4	3	293	4	295	1e-63	226
tr:A0A0B0HUD0_9BACI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.72	209	93	3	83	291	5	203	1e-63	211
rs:WP_046438762	methenyltetrahydrofolate cyclohydrolase [Corynebacterium kutscheri].	42.57	296	151	6	1	292	1	281	1e-63	213
rs:WP_006945857	MULTISPECIES: methylenetetrahydrofolate dehydrogenase [Rhodococcus].	40.55	291	162	4	1	291	4	283	1e-63	214
tr:A0A0B4HUM0_9HYPO	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:KID93871.1}; Flags: Fragment;	42.27	291	161	3	1	288	175	461	1e-63	227
tr:A0A0B4FDY1_9HYPO	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:KID72225.1}; Flags: Fragment;	42.27	291	161	3	1	288	134	420	1e-63	226
rs:WP_028701034	methenyltetrahydrofolate cyclohydrolase [Propionibacterium acidipropionici].	41.26	286	158	4	1	286	1	276	1e-63	213
rs:WP_045937754	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-495].	42.96	291	155	5	1	291	1	280	1e-63	213
rs:WP_033279269	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-525].	43.10	290	153	3	6	295	5	282	1e-63	213
tr:D6WUB5_TRICA	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EFA07236.1};	42.71	295	161	4	3	293	8	298	1e-63	226
rs:WP_014515784	5,10-methylene-tetrahydrofolate dehydrogenase [Thermus sp. CCB_US3_UF1].	43.55	287	146	5	3	289	4	274	1e-63	213
tr:J5THE0_TRIAS	SubName: Full=C1-tetrahydrofolate synthase, Mis1p {ECO:0000313|EMBL:EJT50931.1};	40.20	306	165	6	1	292	77	378	1e-63	226
tr:D5UUK3_TSUPD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.40	297	166	5	1	297	7	292	1e-63	214
rs:XP_008192718	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Tribolium castaneum].	42.71	295	161	4	3	293	27	317	1e-63	226
rs:WP_027130555	5,10-methylene-tetrahydrofolate cyclohydrolase [Gemella cuniculi].	42.01	288	154	4	3	289	2	277	1e-63	213
rs:XP_975938	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X3 [Tribolium castaneum].	42.71	295	161	4	3	293	20	310	1e-63	226
rs:WP_029151377	methenyltetrahydrofolate cyclohydrolase [Microbacterium indicum].	40.80	299	164	6	1	293	1	292	2e-63	214
rs:XP_011307447	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Fopius arisanus].	42.12	292	161	4	5	292	44	331	2e-63	226
rs:WP_025936629	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus sp. scB245a_518D8].	40.75	292	158	4	1	292	1	277	2e-63	213
rs:XP_007680307	hypothetical protein BAUCODRAFT_27658 [Baudoinia compniacensis UAMH 10762].	42.12	292	162	3	1	289	1	288	2e-63	226
rs:WP_023599591	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus johnsonii].	41.40	285	155	3	4	286	3	277	2e-63	213
rs:WP_028785690	methenyltetrahydrofolate cyclohydrolase [Terracoccus sp. 273MFTsu3.1].	41.30	293	159	5	1	293	1	280	2e-63	213
rs:WP_028705187	methenyltetrahydrofolate cyclohydrolase [Propionibacteriaceae bacterium P6A17].	41.61	286	156	4	1	286	1	275	2e-63	213
rs:WP_046650807	methenyltetrahydrofolate cyclohydrolase [Corynebacterium xerosis].	40.14	294	159	5	1	291	1	280	2e-63	213
rs:WP_045573435	methenyltetrahydrofolate cyclohydrolase [Desulfosporosinus sp. I2].	39.44	284	160	4	3	286	2	273	2e-63	213
rs:WP_030393370	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomycetaceae].	42.96	291	155	5	1	291	1	280	2e-63	213
tr:A0A094ETM7_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY82116.1};	40.54	296	169	3	1	293	170	461	2e-63	227
rs:WP_031542630	methenyltetrahydrofolate cyclohydrolase [Mesoplasma photuris].	42.41	290	158	3	4	293	2	282	2e-63	213
rs:WP_018023396	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium ulceribovis].	41.50	294	155	5	1	291	1	280	2e-63	213
tr:K7J183_NASVI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:NV15114-PA};	42.81	292	159	4	5	292	9	296	2e-63	225
rs:XP_007385666	FTHFS-domain-containing protein [Punctularia strigosozonata HHB-11173 SS5].	43.58	296	157	4	2	291	4	295	2e-63	226
tr:A0A086NGG7_METAN	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:KFG80235.1};	42.27	291	161	3	1	288	154	440	2e-63	226
rs:WP_031852754	methenyltetrahydrofolate cyclohydrolase, partial [Vibrio parahaemolyticus].	50.45	220	105	1	1	220	1	216	2e-63	211
tr:A0A098LYV3_9SAUR	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase {ECO:0000313|EMBL:JAC95144.1};	43.62	298	157	5	2	293	3	295	2e-63	225
rs:WP_027692508	methenyltetrahydrofolate cyclohydrolase [Rathayibacter toxicus].	39.26	298	171	5	1	293	1	293	2e-63	213
rs:XP_008192717	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Tribolium castaneum].	42.71	295	161	4	3	293	60	350	2e-63	226
rs:WP_014144430	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces cattleya].	40.21	286	161	5	1	286	1	276	2e-63	213
rs:WP_044022504	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. SG-1].	40.48	289	157	4	5	293	6	279	2e-63	213
tr:A0A078B6A6_STYLE	SubName: Full=Bifunctional protein {ECO:0000313|EMBL:CDW89889.1};	42.58	256	138	4	35	286	1	251	2e-63	212
rs:WP_015262820	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfitobacterium dichloroeliminans].	39.79	284	159	3	3	286	2	273	2e-63	213
tr:N4UVM9_COLOR	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:ENH79853.1};	41.55	296	166	3	1	293	1	292	2e-63	225
rs:XP_011394879	C-1-tetrahydrofolate synthase, variant [Neurospora crassa OR74A].	42.51	287	151	4	3	286	2	277	2e-63	225
rs:WP_030230892	methenyltetrahydrofolate cyclohydrolase [Streptomyces lavendulae].	42.12	292	159	5	1	292	1	282	2e-63	213
rs:XP_008079361	P-loop containing nucleoside triphosphate hydrolase [Glarea lozoyensis ATCC 20868].	42.12	292	162	3	1	289	1	288	2e-63	225
rs:WP_029102788	5,10-methylene-tetrahydrofolate cyclohydrolase [Moraxella caprae].	39.58	288	163	3	3	290	2	278	2e-63	213
rs:XP_007816209	C-1-tetrahydrofolate synthase [Metarhizium robertsii ARSEF 23].	42.27	291	161	3	1	288	175	461	2e-63	226
rs:WP_029544740	methenyltetrahydrofolate cyclohydrolase [Rhodococcus sp. BCP1].	40.55	291	162	4	1	291	4	283	2e-63	213
tr:A0A0A6ZNI1_SHIDY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.34	227	111	1	1	227	1	223	2e-63	211
tr:A6CL43_9BACI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.48	289	157	4	5	293	8	281	2e-63	213
rs:WP_044333023	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. WHSC-8].	43.84	292	157	3	3	294	2	286	2e-63	213
rs:WP_016473316	MULTISPECIES: FolD 2 [Streptomyces].	40.56	286	160	4	1	286	1	276	2e-63	213
rs:XP_002905421	bifunctional folD protein [Phytophthora infestans T30-4].	41.61	298	155	4	3	289	2	291	2e-63	213
rs:WP_002770752	5,10-methylene-tetrahydrofolate dehydrogenase [Leptonema illini].	40.69	290	156	4	5	293	9	283	2e-63	213
sp:FOLD2_LACJO	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.25	289	152	4	4	292	3	279	2e-63	213
rs:WP_045262221	methenyltetrahydrofolate cyclohydrolase [Microbacterium oxydans].	41.61	298	163	7	1	293	1	292	2e-63	213
tr:A0A0B4EWQ7_METAN	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:KID66375.1}; Flags: Fragment;	42.27	291	161	3	1	288	175	461	2e-63	226
rs:WP_003789598	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces viscosus].	39.93	298	166	6	2	293	8	298	2e-63	213
tr:A0A034WFL5_BACDO	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:JAC52930.1};	44.52	292	154	4	2	289	4	291	2e-63	225
rs:WP_009747257	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces sp. oral taxon 175].	39.60	298	167	6	2	293	8	298	2e-63	213
tr:A0A0D7BMW1_9HOMO	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:KIY70931.1};	43.58	296	157	4	2	291	4	295	2e-63	225
rs:XP_011203924	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Bactrocera dorsalis].	44.52	292	154	4	2	289	35	322	2e-63	225
rs:XP_003384919	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Amphimedon queenslandica].	43.92	296	157	4	1	291	11	302	2e-63	225
rs:XP_008205570	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Nasonia vitripennis].	42.81	292	159	4	5	292	23	310	2e-63	225
rs:XP_010381995	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Rhinopithecus roxellana].	42.57	296	160	5	3	293	4	294	2e-63	225
tr:S0E185_GIBF5	SubName: Full=Probable C1-tetrahydrofolate synthase {ECO:0000313|EMBL:CCT68445.1};	42.21	289	160	3	1	286	1	285	2e-63	225
rs:WP_037308164	5,10-methylene-tetrahydrofolate cyclohydrolase [Saccharomonospora viridis].	42.07	290	153	3	1	290	1	275	2e-63	213
rs:WP_029212050	methenyltetrahydrofolate cyclohydrolase [Arsenicicoccus bolidensis].	40.75	292	165	5	1	292	1	284	2e-63	213
sp:FOLD_HELMI	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.72	290	158	4	1	290	1	279	2e-63	213
tr:A0A093XXT3_PENMA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFX50048.1};	43.15	292	154	3	1	290	87	368	2e-63	227
rs:WP_007557162	methylenetetrahydrofolate dehydrogenase [Candidatus Liberibacter americanus].	45.30	298	144	8	3	292	2	288	2e-63	213
rs:WP_045313231	methenyltetrahydrofolate cyclohydrolase [Lechevalieria aerocolonigenes].	42.37	295	150	7	1	292	1	278	2e-63	213
tr:A0A094QNC5_9ZZZZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGA16056.1};	40.41	292	163	4	1	292	1	281	3e-63	213
rs:WP_042620802	methenyltetrahydrofolate cyclohydrolase [Corynebacterium marinum].	40.61	293	157	5	1	290	1	279	3e-63	213
tr:A0A0C3QWW2_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIO34451.1};	42.66	293	158	4	5	291	30	318	3e-63	225
rs:WP_030241481	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-350].	42.96	291	155	5	1	291	1	280	3e-63	213
rs:XP_008554155	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Microplitis demolitor].	43.15	292	158	4	5	292	7	294	3e-63	225
rs:WP_020134757	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. 351MFTsu5.1].	40.34	290	159	2	3	292	4	279	3e-63	213
rs:WP_010292267	tetrahydrofolate dehydrogenase [Clostridium senegalense].	40.97	288	159	2	6	293	5	281	3e-63	213
rs:WP_003649082	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus gasseri].	43.10	290	151	6	4	292	3	279	3e-63	213
rs:WP_027873889	5,10-methylene-tetrahydrofolate cyclohydrolase [Spongiibacter marinus].	39.46	294	163	3	1	293	1	280	3e-63	213
rs:WP_006351530	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus amylolyticus].	41.72	290	157	4	3	292	2	279	3e-63	213
tr:A0A069DXA5_9HEMI	SubName: Full=Putative methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:JAC88530.1}; Flags: Fragment;	41.36	295	165	4	3	293	1	291	3e-63	225
rs:WP_034089877	methenyltetrahydrofolate cyclohydrolase [Streptacidiphilus albus].	40.41	292	163	5	1	292	1	281	3e-63	213
rs:WP_046332285	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus kimbladii].	40.21	291	160	4	3	292	2	279	3e-63	213
rs:XP_002053617	GJ23253 [Drosophila virilis].	42.57	296	162	4	1	292	3	294	3e-63	225
rs:WP_009233446	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces johnsonii].	39.93	298	166	6	2	293	8	298	3e-63	213
rs:WP_004895365	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus johnsonii].	42.91	289	153	4	4	292	3	279	3e-63	213
rs:WP_010851840	methylenetetrahydrofolate dehydrogenase [Tetrasphaera elongata].	39.93	293	166	6	1	292	1	284	3e-63	213
rs:WP_018601690	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium sp. 155].	43.36	286	151	4	1	286	1	275	3e-63	213
rs:WP_045933500	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL B-1568].	40.75	292	163	4	1	292	1	282	3e-63	213
tr:Q8BXX7_MOUSE	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:BAC31419.1};	42.23	296	162	4	3	293	4	295	3e-63	223
tr:K8E0A1_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.20	284	155	3	3	286	2	273	3e-63	213
rs:WP_015071133	bifunctional protein FolD [Propionibacterium acidipropionici].	40.91	286	159	4	1	286	1	276	3e-63	213
rs:WP_035761901	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. PAO19].	40.54	296	161	6	1	292	3	287	3e-63	213
rs:WP_013805768	5,10-methylene-tetrahydrofolate dehydrogenase [Amycolicicoccus subflavus].	41.30	293	161	4	1	293	1	282	3e-63	213
rs:XP_005322847	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Ictidomys tridecemlineatus].	42.23	296	162	4	3	293	4	295	3e-63	225
tr:U3IZH7_ANAPL	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAPLP00000012653}; Flags: Fragment;	45.98	261	134	3	3	257	37	296	3e-63	213
rs:WP_027523452	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. Ec3.3].	41.52	289	163	2	1	289	1	283	3e-63	213
tr:M4BXM2_HYAAE	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:HpaP811303};	42.80	264	137	4	40	293	1	260	3e-63	212
rs:WP_046095567	methenyltetrahydrofolate cyclohydrolase [Corynebacterium ulcerans].	43.20	294	148	6	1	290	1	279	3e-63	213
rs:XP_009588442	PREDICTED: bifunctional protein FolD 2-like [Nicotiana tomentosiformis].	53.47	202	88	2	94	293	29	226	3e-63	211
rs:WP_003146178	tetrahydrofolate dehydrogenase [Gemella haemolysans].	42.16	287	153	4	4	289	3	277	3e-63	213
rs:XP_006559841	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Apis mellifera].	42.81	292	159	4	5	292	9	296	3e-63	225
rs:XP_012746177	hypothetical protein GMDG_07723 [Pseudogymnoascus destructans 20631-21].	41.24	291	164	3	6	293	6	292	3e-63	224
rs:WP_013423222	5,10-methylene-tetrahydrofolate dehydrogenase [Frankia sp. EuI1c].	41.03	290	156	3	1	290	1	275	3e-63	213
tr:A0A0C6AP47_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJR77289.1};	40.46	304	166	4	1	293	1	300	3e-63	225
tr:N4U0R0_FUSC1	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:ENH62381.1};	42.56	289	159	3	1	286	1	285	3e-63	224
rs:WP_029416369	methenyltetrahydrofolate cyclohydrolase [Brevundimonas bacteroides].	45.73	293	148	6	2	293	4	286	3e-63	213
rs:XP_002676767	predicted protein [Naegleria gruberi].	37.95	303	169	6	5	291	11	310	3e-63	213
rs:WP_014762528	5,10-methylene-tetrahydrofolate dehydrogenase [Sinorhizobium fredii].	43.54	294	145	4	3	292	2	278	3e-63	213
rs:XP_012528009	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Monomorium pharaonis].	42.81	292	159	4	5	292	9	296	3e-63	224
tr:A0A067MYW4_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDQ19865.1};	41.84	294	161	4	4	291	11	300	3e-63	224
rs:XP_012528008	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Monomorium pharaonis].	42.81	292	159	4	5	292	23	310	3e-63	225
rs:WP_045187481	methenyltetrahydrofolate cyclohydrolase [Terrabacter sp. 28].	41.44	292	158	5	1	292	1	279	3e-63	213
tr:Q5EBC3_RAT	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase {ECO:0000313|EMBL:AAH89800.1};	42.76	297	159	6	3	293	4	295	3e-63	224
sp:C1TC_RAT	RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3; Contains: RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed;	42.23	296	162	4	3	293	4	295	3e-63	224
rs:WP_044439886	5,10-methylene-tetrahydrofolate cyclohydrolase [Agreia bicolorata].	42.41	290	156	2	1	290	1	279	3e-63	213
tr:T1E4K9_CROHD	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:JAA95437.1};	43.29	298	158	5	2	293	3	295	3e-63	224
tr:G3V6S5_RAT	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSRNOP00000008374}; SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase, isoform CRA_b {ECO:0000313|EMBL:EDM03656.1};	42.23	296	162	4	3	293	4	295	3e-63	224
rs:WP_029464334	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Chitinophaga sp. JGI 0001002-D04].	53.85	195	90	0	70	264	4	198	3e-63	209
rs:WP_019379654	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus oceanisediminis].	39.37	287	159	3	5	291	6	277	3e-63	213
tr:S5Y1F3_PARAH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	44.67	291	151	4	2	291	10	291	3e-63	213
rs:WP_035927009	methenyltetrahydrofolate cyclohydrolase [Kocuria polaris].	41.02	295	165	6	1	291	1	290	4e-63	213
rs:XP_003924472	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Saimiri boliviensis boliviensis].	41.55	296	164	4	3	293	4	295	4e-63	224
tr:W9ME21_FUSOX	SubName: Full=Formate-tetrahydrofolate ligase {ECO:0000313|EMBL:EWZ90252.1};	42.56	289	159	3	1	286	170	454	4e-63	226
rs:WP_027736011	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. CNT360].	40.91	286	159	5	1	286	1	276	4e-63	213
rs:WP_022924988	5,10-methylene-tetrahydrofolate dehydrogenase [Serinicoccus marinus].	39.86	291	162	5	1	291	1	278	4e-63	213
tr:W9K550_FUSOX	SubName: Full=Formate-tetrahydrofolate ligase {ECO:0000313|EMBL:EWZ37080.1};	42.56	289	159	3	1	286	170	454	4e-63	226
tr:W8B1E2_CERCA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:JAB90833.1};	45.02	291	152	4	3	289	5	291	4e-63	224
tr:A0A0C3EA82_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIM65259.1};	42.86	294	158	4	2	289	5	294	4e-63	224
rs:WP_013659884	5,10-methylene-tetrahydrofolate dehydrogenase [Marinomonas mediterranea].	38.23	293	167	2	1	293	1	279	4e-63	212
rs:WP_015354771	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium liflandii].	41.24	291	160	4	1	291	1	280	4e-63	212
tr:E0XWW6_9DELT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.67	300	151	5	2	291	5	293	4e-63	213
rs:WP_045878145	5,10-methylene-tetrahydrofolate cyclohydrolase [Frankia sp. DC12].	40.56	286	155	3	1	286	1	271	4e-63	213
rs:XP_004529194	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Ceratitis capitata].	45.02	291	152	4	3	289	38	324	4e-63	224
rs:WP_015452652	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Liberibacter asiaticus].	42.86	294	159	5	3	293	2	289	4e-63	213
tr:A0A088ABT0_APIME	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:GB48881-PA};	42.81	292	159	4	5	292	23	310	4e-63	224
rs:WP_017618855	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis gilva].	41.98	293	159	4	1	293	1	282	4e-63	212
rs:WP_015305183	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium smegmatis].	42.41	290	157	4	1	290	1	280	4e-63	212
rs:WP_035748822	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. 35W].	39.66	295	168	6	2	292	6	294	4e-63	213
rs:WP_009502177	5,10-methylene-tetrahydrofolate dehydrogenase [Moraxella macacae].	39.52	291	165	3	3	293	2	281	4e-63	212
sp:FOLD_MYCUA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.24	291	160	4	1	291	1	280	4e-63	212
tr:Q6DI12_DANRE	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) {ECO:0000313|EMBL:AAH75779.1};	43.73	295	157	4	1	290	1	291	4e-63	224
rs:XP_002872938	hypothetical protein ARALYDRAFT_490507 [Arabidopsis lyrata subsp. lyrata].	48.86	219	106	2	75	291	91	305	4e-63	213
rs:WP_009884943	5,10-methylene-tetrahydrofolate dehydrogenase [Brevibacterium linens].	42.76	297	157	6	1	291	1	290	5e-63	212
rs:WP_046679986	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. DMB20].	38.75	289	162	3	5	293	8	281	5e-63	212
tr:A0A093X9X8_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFX89448.1};	40.54	296	169	3	1	293	171	462	5e-63	225
rs:XP_002127871	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Ciona intestinalis].	44.41	295	154	4	3	291	2	292	5e-63	224
rs:WP_046017852	5,10-methylene-tetrahydrofolate cyclohydrolase [Marinomonas sp. S3726].	38.23	293	167	2	1	293	1	279	5e-63	212
tr:W8BMC6_CERCA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:JAB90834.1};	45.02	291	152	4	3	289	36	322	5e-63	224
rs:WP_035119898	methenyltetrahydrofolate cyclohydrolase [Corynebacterium freneyi].	40.48	294	158	5	1	291	1	280	5e-63	212
tr:F1QXP5_DANRE	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSDARP00000020770};	43.73	295	157	4	1	290	1	291	5e-63	224
tr:A3Z7V0_9SYNE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.80	286	148	3	6	288	14	295	5e-63	213
rs:XP_004529195	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Ceratitis capitata].	45.02	291	152	4	3	289	36	322	5e-63	224
rs:WP_038001491	5,10-methylene-tetrahydrofolate cyclohydrolase [Synechococcus sp. RS9917].	45.80	286	148	3	6	288	5	286	5e-63	213
tr:H0GVB3_SACCK	SubName: Full=Ade3p {ECO:0000313|EMBL:EHN02229.1};	40.46	304	166	4	1	293	1	300	5e-63	224
rs:XP_012319592	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Aotus nancymaae].	41.89	296	163	4	3	293	4	295	5e-63	224
sp:FOLD_CLOTE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.07	279	159	3	6	284	5	272	5e-63	212
sp:FOLD_MYCMM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.24	291	160	4	1	291	1	280	5e-63	212
rs:WP_043677775	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces xylophagus].	42.07	290	156	3	6	295	5	282	5e-63	212
rs:WP_003048305	5,10-methylene-tetrahydrofolate dehydrogenase [Thermus aquaticus].	42.71	288	149	5	2	289	3	274	5e-63	212
rs:WP_020788462	bifunctional protein FolD [Mycobacterium sp. 012931].	41.24	291	160	4	1	291	1	280	5e-63	212
rs:WP_036467056	methenyltetrahydrofolate cyclohydrolase [Mycobacterium triplex].	41.10	292	161	4	1	292	1	281	5e-63	212
rs:WP_043406184	methenyltetrahydrofolate cyclohydrolase [Mycobacterium rufum].	42.56	289	150	5	1	286	4	279	5e-63	212
rs:WP_023958010	ABC transporter [Paenibacillus sp. JCM 10914].	39.59	293	162	4	1	293	3	280	6e-63	212
tr:A0A093Y9Y4_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFX99552.1};	40.54	296	169	3	1	293	171	462	6e-63	225
rs:WP_020083230	5,10-methylene-tetrahydrofolate dehydrogenase [gamma proteobacterium SCGC AAA160-D02].	38.78	294	165	3	1	293	1	280	6e-63	212
rs:WP_031053259	methenyltetrahydrofolate cyclohydrolase [Streptomyces ochraceiscleroticus].	40.07	292	164	5	1	292	1	281	6e-63	212
sp:FOLD_LACGA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.10	290	151	6	4	292	3	279	6e-63	212
rs:WP_037050613	5,10-methylene-tetrahydrofolate cyclohydrolase [Pseudonocardia autotrophica].	42.12	292	158	3	2	293	9	289	6e-63	212
rs:WP_015736068	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus sp. Y412MC10].	39.32	295	162	5	1	293	1	280	6e-63	212
rs:XP_002954160	hypothetical protein VOLCADRAFT_44449, partial [Volvox carteri f. nagariensis].	41.16	294	164	3	3	290	1	291	6e-63	212
rs:WP_046977059	methenyltetrahydrofolate cyclohydrolase [Rhizobium phaseoli].	43.06	288	153	6	6	291	12	290	6e-63	212
rs:WP_028858690	5,10-methylene-tetrahydrofolate cyclohydrolase [Psychrobacter phenylpyruvicus].	39.18	291	166	3	2	292	5	284	6e-63	212
tr:M1CPV5_SOLTU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:PGSC0003DMT400072215};	52.17	207	93	2	89	293	31	233	6e-63	210
rs:XP_003697425	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Apis florea].	42.47	292	160	4	5	292	9	296	6e-63	224
tr:A0A0C6CXK1_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJR97017.1};	40.46	304	166	4	1	293	1	300	6e-63	224
rs:WP_004631842	tetrahydrofolate dehydrogenase [Gemella morbillorum].	41.61	286	154	4	4	288	3	276	6e-63	212
rs:WP_036661273	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. FSL H8-457].	39.32	295	162	5	1	293	1	280	6e-63	212
rs:WP_037147890	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	40.75	292	162	4	1	292	1	281	6e-63	212
rs:WP_008718073	bifunctional protein FolD [Rhodococcus sp. AW25M09].	41.10	292	161	5	1	292	1	281	7e-63	212
rs:XP_007473078	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Monodelphis domestica].	44.03	293	155	4	3	290	4	292	7e-63	223
rs:WP_022029892	bifunctional protein FolD [Clostridium sp. CAG:762].	40.91	286	153	4	5	290	2	271	7e-63	211
tr:D9MP90_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	51.42	212	93	3	82	293	3	204	7e-63	209
rs:XP_006688354	C-1-tetrahydrofolate synthase mitochondrial precursor [Candida tenuis ATCC 10573].	41.72	302	159	4	1	289	31	328	7e-63	224
rs:WP_021921590	bifunctional protein FolD [Acholeplasma sp. CAG:878].	43.57	280	137	6	5	284	15	273	7e-63	211
rs:WP_046748840	methenyltetrahydrofolate cyclohydrolase [Microbacterium sp. Ag1].	41.08	297	166	6	1	293	1	292	7e-63	212
rs:XP_003844807	similar to C-1-tetrahydrofolate synthase [Leptosphaeria maculans JN3].	41.46	287	161	3	1	284	152	434	7e-63	224
rs:WP_023028338	FolD protein [Corynebacterium sp. KPL1824].	42.96	291	155	4	1	291	1	280	7e-63	211
rs:WP_027824667	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus psittaci].	41.44	292	155	6	3	292	2	279	8e-63	211
rs:WP_003145716	tetrahydrofolate dehydrogenase [Gemella haemolysans].	41.96	286	153	4	4	288	3	276	8e-63	211
rs:WP_032404718	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	40.75	292	162	4	1	292	1	281	8e-63	211
rs:WP_003866522	5,10-methylene-tetrahydrofolate dehydrogenase [Propionibacterium acnes].	40.89	291	162	4	1	291	1	281	8e-63	211
tr:E2AG54_CAMFO	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:EFN67545.1}; Flags: Fragment;	45.04	282	147	4	15	292	2	279	8e-63	223
rs:XP_009542726	hypothetical protein HETIRDRAFT_122342 [Heterobasidion irregulare TC 32-1].	44.37	293	153	4	5	291	11	299	8e-63	224
rs:WP_013398553	5,10-methylene-tetrahydrofolate dehydrogenase [Rothia dentocariosa].	41.89	296	157	7	4	292	3	290	8e-63	212
rs:XP_008564471	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Galeopterus variegatus].	41.98	293	161	4	3	290	4	292	8e-63	223
gpu:CP011545_505	Bifunctional protein FolD [Corynebacterium testudinoris]	42.07	290	157	4	1	290	71	349	8e-63	214
tr:A0A094H6J7_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFZ10577.1};	40.88	296	168	3	1	293	172	463	8e-63	225
rs:XP_003345899	hypothetical protein SMAC_06300 [Sordaria macrospora k-hell].	41.87	289	154	4	3	288	211	488	8e-63	225
rs:XP_003869457	Mis11 protein [Candida orthopsilosis Co 90-125].	42.23	296	162	4	1	291	1	292	8e-63	224
tr:A0A0B0ML16_GOSAR	SubName: Full=Bifunctional FolD {ECO:0000313|EMBL:KHG01465.1};	38.76	307	127	3	3	293	9	270	9e-63	211
tr:A0A0D3H5A9_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART09G05630.1};	44.79	259	137	2	34	290	9	263	9e-63	211
tr:G0UIA1_9LACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.69	293	149	6	3	290	9	290	9e-63	212
tr:A0A0D3S368_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJS20014.1};	40.46	304	166	4	1	293	1	300	9e-63	223
rs:WP_018020059	hypothetical protein [Corynebacterium ciconiae].	40.55	291	162	4	1	291	1	280	9e-63	211
tr:A0A094DQF0_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY61680.1};	40.88	296	168	3	1	293	171	462	9e-63	224
rs:WP_014814440	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium chubuense].	42.31	286	155	4	1	286	4	279	1e-62	211
tr:H0GGU8_SACCK	SubName: Full=Ade3p {ECO:0000313|EMBL:EHN06973.1};	40.46	304	166	4	1	293	1	300	1e-62	223
tr:A0A031K3Y4_9SPHN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.96	270	147	3	22	291	7	269	1e-62	211
tr:Q3TW74_MOUSE	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:BAE35392.1};	42.23	296	162	4	3	293	4	295	1e-62	223
tr:W7LYX3_GIBM7	SubName: Full=Formate-tetrahydrofolate ligase {ECO:0000313|EMBL:EWG40624.1};	42.21	289	160	3	1	286	168	452	1e-62	224
tr:A0A0C6D0W7_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJS06370.1};	40.46	304	166	4	1	293	1	300	1e-62	223
tr:A0A0D3SGV9_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJS24502.1};	40.46	304	166	4	1	293	1	300	1e-62	223
tr:A0A0C6BL73_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJR78778.1};	40.46	304	166	4	1	293	1	300	1e-62	223
rs:XP_007473077	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Monodelphis domestica].	44.03	293	155	4	3	290	4	292	1e-62	223
rs:WP_037107650	5,10-methylene-tetrahydrofolate cyclohydrolase [Rhodococcus fascians].	39.45	289	157	3	1	289	2	272	1e-62	211
rs:WP_036637127	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. FSL R5-808].	39.32	295	162	5	1	293	1	280	1e-62	211
rs:WP_003650272	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus gasseri].	43.10	290	151	6	4	292	3	279	1e-62	211
tr:A0A0C9ZPC9_9HOMO	SubName: Full=Unplaced genomic scaffold scaffold_1, whole genome shotgun sequence {ECO:0000313|EMBL:KIK31206.1};	42.52	294	159	4	2	289	3	292	1e-62	223
tr:A0A0C6BIS0_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJR87669.1};	40.46	304	166	4	1	293	1	300	1e-62	223
tr:A0A0C6BSX0_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJR83227.1};	40.46	304	166	4	1	293	1	300	1e-62	223
rs:WP_030622147	methenyltetrahydrofolate cyclohydrolase [Streptomyces sclerotialus].	40.75	292	162	5	1	292	1	281	1e-62	211
rs:XP_001641533	predicted protein [Nematostella vectensis].	42.71	295	160	4	2	291	4	294	1e-62	223
tr:A0A0C5IIB4_YEASX	SubName: Full=ADE3 protein {ECO:0000313|EMBL:AJP38974.1};	40.46	304	166	4	1	293	1	300	1e-62	223
rs:WP_005518547	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodococcus equi].	40.21	291	163	4	1	291	4	283	1e-62	211
tr:A0A0C6D8G7_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJR98513.1};	40.46	304	166	4	1	293	1	300	1e-62	223
rs:WP_035723434	methenyltetrahydrofolate cyclohydrolase [Fodinicurvata fenggangensis].	37.19	285	172	3	6	290	14	291	1e-62	212
tr:K9INE4_DESRO	SubName: Full=Putative methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:JAA49378.1};	41.89	296	163	4	3	293	4	295	1e-62	223
tr:A0A0C6BDV9_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJR81736.1};	40.46	304	166	4	1	293	1	300	1e-62	223
tr:B3LI33_YEAS1	SubName: Full=C1-tetrahydrofolate synthase {ECO:0000313|EMBL:EDV10054.1};	40.46	304	166	4	1	293	1	300	1e-62	223
tr:E7Q4A8_YEASB	SubName: Full=Ade3p {ECO:0000313|EMBL:EGA58552.1};	40.46	304	166	4	1	293	1	300	1e-62	223
rs:WP_020117192	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces canus].	39.38	292	163	2	1	292	2	279	1e-62	211
rs:WP_037285735	methenyltetrahydrofolate cyclohydrolase [Rothia aeria].	41.55	296	158	7	4	292	3	290	1e-62	211
rs:WP_018017585	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium capitovis].	40.89	291	161	4	1	291	1	280	1e-62	211
tr:T1KCF1_TETUR	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:tetur08g07400.1};	41.75	297	159	4	3	293	29	317	1e-62	212
rs:XP_007843810	c-1-tetrahydrofolate synthase [Moniliophthora roreri MCA 2997].	42.81	292	157	4	6	291	12	299	1e-62	223
rs:WP_026469906	5,10-methylene-tetrahydrofolate cyclohydrolase [Alkanindiges illinoisensis].	39.73	292	163	4	3	293	2	281	1e-62	211
tr:A0A0D3SLD5_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJS25506.1};	40.46	304	166	4	1	293	1	300	1e-62	223
rs:WP_023635211	hypothetical protein [Corynebacterium ulcerans].	42.86	294	149	6	1	290	1	279	1e-62	211
rs:XP_008270106	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Oryctolagus cuniculus].	41.55	296	164	4	3	293	4	295	1e-62	223
tr:A0A0C6C4N4_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJR87212.1};	40.46	304	166	4	1	293	1	300	1e-62	223
rs:WP_040084990	methenyltetrahydrofolate cyclohydrolase [Corynebacterium humireducens].	42.76	290	147	6	1	286	1	275	1e-62	211
sp:C1TC_YEAST	RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3;	40.46	304	166	4	1	293	1	300	1e-62	223
rs:WP_018112237	5,10-methylene-tetrahydrofolate dehydrogenase [Thermus igniterrae].	42.16	287	150	5	3	289	4	274	1e-62	211
rs:XP_006207034	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Vicugna pacos].	40.88	296	166	4	3	293	4	295	1e-62	223
tr:W5N5H3_LEPOC	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLOCP00000015882};	43.77	297	156	5	3	293	4	295	1e-62	223
tr:A0A084P7Z0_STACH	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFA46325.1};	41.52	289	155	4	1	286	1	278	1e-62	223
gp:BC008523_1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase [Mus musculus]	42.23	296	162	4	3	293	4	295	1e-62	223
tr:A0A0D3SQR0_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJS27974.1};	40.46	304	166	4	1	293	1	300	1e-62	223
rs:WP_029192734	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus harenae].	39.58	288	159	3	5	292	6	278	1e-62	211
tr:A0A0D8HE58_9ACTN	SubName: Full=Bifunctional protein FolD protein {ECO:0000313|EMBL:KJF16245.1};	42.36	288	157	3	3	290	2	280	1e-62	211
rs:WP_032376817	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	40.41	292	163	4	1	292	1	281	1e-62	211
sp:C1TC_MOUSE	RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3; Contains: RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed;	42.23	296	162	4	3	293	4	295	1e-62	223
tr:A0A094IEP1_9PEZI	RecName: Full=Eukaryotic translation initiation factor 3 subunit I {ECO:0000256|SAAS:SAAS00003572};	40.54	296	169	3	1	293	565	856	1e-62	226
rs:WP_027531700	methenyltetrahydrofolate cyclohydrolase [Bradyrhizobium sp. WSM3983].	43.73	295	154	5	3	295	2	286	1e-62	211
tr:A0A0C6DJ09_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJS07371.1};	40.46	304	166	4	1	293	1	300	1e-62	223
rs:XP_005160670	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Danio rerio].	43.05	295	157	5	3	291	25	314	1e-62	220
tr:A0A024Y2K3_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:EWG95792.1};	40.46	304	166	4	1	293	1	300	1e-62	223
tr:W6MSN8_9ASCO	SubName: Full=Genomic scaffold, Kuraishia_capsulata_scaffold_5 {ECO:0000313|EMBL:CDK28242.1};	40.13	299	166	4	1	293	36	327	1e-62	223
rs:WP_003798126	5,10-methylene-tetrahydrofolate dehydrogenase [Arthrobacter globiformis].	41.22	296	162	7	2	292	7	295	1e-62	211
rs:WP_007672359	5,10-methylene-tetrahydrofolate dehydrogenase [Caulobacter sp. AP07].	43.21	287	155	4	4	290	2	280	1e-62	211
tr:A0A0D6EJZ7_SPOSA	SubName: Full=SPOSA6832_01526-mRNA-1:cds {ECO:0000313|EMBL:CEQ39955.1};	43.14	299	157	5	2	291	9	303	2e-62	223
tr:U7V2T7_9MICC	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.55	296	158	7	4	292	11	298	2e-62	211
tr:G3Y245_ASPNA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHA23451.1};	43.00	293	160	3	1	290	1	289	2e-62	223
rs:XP_001875392	predicted protein [Laccaria bicolor S238N-H82].	41.55	296	163	4	2	291	8	299	2e-62	223
tr:A0A084RBH3_STACH	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFA73558.1};	41.52	289	155	4	1	286	1	278	2e-62	223
rs:XP_010586988	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Loxodonta africana].	41.89	296	163	4	3	293	4	295	2e-62	223
rs:WP_025738464	methenyltetrahydrofolate cyclohydrolase [Mycobacterium genavense].	41.10	292	161	4	1	292	1	281	2e-62	211
rs:WP_028433947	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. TAA486].	39.04	292	168	5	1	292	1	282	2e-62	211
tr:A2QEV9_ASPNC	SubName: Full=Aspergillus niger contig An02c0400, genomic contig {ECO:0000313|EMBL:CAK44509.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CAK44509.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CAK44509.1}; EC=6.3.4.3 {ECO:0000313|EMBL:CAK44509.1};	43.00	293	160	3	1	290	1	289	2e-62	223
tr:A0A0C6BFG0_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJR80735.1};	40.46	304	166	4	1	293	1	300	2e-62	223
rs:XP_011805215	PREDICTED: LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic [Colobus angolensis palliatus].	41.89	296	162	5	3	293	112	402	2e-62	223
rs:WP_029265856	methenyltetrahydrofolate cyclohydrolase [Microbacterium sp. Cr-K32].	41.95	298	162	7	1	293	1	292	2e-62	211
rs:WP_006888049	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Rothia].	41.55	296	158	7	4	292	3	290	2e-62	211
tr:H2U4F9_TAKRU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTRUP00000031821}; Flags: Fragment;	44.00	300	157	5	1	293	2	297	2e-62	223
rs:XP_002562911	Pc20g03600 [Penicillium rubens Wisconsin 54-1255].	43.34	293	159	3	1	290	1	289	2e-62	223
rs:WP_031720372	methenyltetrahydrofolate cyclohydrolase [Mycobacterium tuberculosis].	40.89	291	161	4	1	291	1	280	2e-62	211
rs:XP_003083266	Cytoplasmic exosomal RNA helicase SKI2, DEAD-box superfamily (ISS) [Ostreococcus tauri].	48.94	235	114	2	54	286	2	232	2e-62	223
rs:XP_462568	DEHA2G23650p [Debaryomyces hansenii CBS767].	41.55	296	164	4	1	291	1	292	2e-62	223
rs:WP_040766192	methenyltetrahydrofolate cyclohydrolase [Tsukamurella sp. 1534].	40.40	297	166	4	1	297	4	289	2e-62	211
rs:WP_032397475	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	41.24	291	160	4	1	291	1	280	2e-62	211
tr:G7XC19_ASPKW	SubName: Full=C1 tetrahydrofolate synthase {ECO:0000313|EMBL:GAA84382.1};	43.00	293	160	3	1	290	1	289	2e-62	223
tr:A0A0D9N316_ASPFL	SubName: Full=Formate--tetrahydrofolate ligase {ECO:0000313|EMBL:KJJ34256.1};	43.34	293	159	3	1	290	1	289	2e-62	223
rs:WP_021607081	tetrahydrofolate dehydrogenase [Actinomyces johnsonii].	39.60	298	167	6	2	293	8	298	2e-62	211
rs:WP_035389812	methenyltetrahydrofolate cyclohydrolase [Ferrimicrobium acidiphilum].	39.93	293	167	3	1	293	1	284	2e-62	211
tr:A0A075FKQ5_9ARCH	SubName: Full=Methylenetetrahydrofolate dehydrogenase (FolD) {ECO:0000313|EMBL:AIE91934.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AIE91934.1}; Flags: Fragment;	44.49	245	123	3	50	292	3	236	2e-62	209
rs:XP_008924082	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Manacus vitellinus].	43.10	297	158	5	3	293	4	295	2e-62	223
tr:G9KBN4_MUSPF	SubName: Full=Methylenetetrahydrofolate dehydrogenase 1 {ECO:0000313|EMBL:AES02309.1}; Flags: Fragment;	40.82	294	165	4	3	291	37	326	2e-62	216
rs:WP_018154879	5,10-methylene-tetrahydrofolate dehydrogenase [Demetria terragena].	41.10	292	159	5	1	292	1	279	2e-62	210
tr:X0WZ18_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S27034 {ECO:0000313|EMBL:GAG36209.1}; Flags: Fragment;	43.20	250	135	1	4	253	3	245	2e-62	209
rs:WP_045195861	methenyltetrahydrofolate cyclohydrolase [Rhodococcus sp. B7740].	41.24	291	160	4	1	291	1	280	2e-62	211
rs:WP_021272081	tetrahydrofolate dehydrogenase [Bacteriovorax sp. BSW11_IV].	40.33	300	158	6	1	295	5	288	2e-62	211
tr:A0A0B8RX81_BOIIR	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase {ECO:0000313|EMBL:JAG67442.1};	43.24	296	157	5	2	291	3	293	2e-62	223
rs:XP_006177818	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Camelus ferus].	40.54	296	167	4	3	293	4	295	2e-62	223
rs:XP_010960559	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Camelus bactrianus].	40.54	296	167	4	3	293	4	295	2e-62	223
rs:WP_026422474	methenyltetrahydrofolate cyclohydrolase [Actinokineospora inagensis].	40.96	293	162	5	1	293	1	282	2e-62	210
sp:FOLD_MYCS2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.64	293	160	4	1	293	1	282	2e-62	210
rs:WP_027860167	methenyltetrahydrofolate cyclohydrolase [Marmoricola sp. URHB0036].	40.61	293	163	4	1	293	1	282	2e-62	211
sp:FOLD_RENSM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.86	294	159	5	1	290	1	289	2e-62	211
tr:A0A0C6D653_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJS00008.1};	40.13	304	167	4	1	293	1	300	2e-62	223
rs:XP_011216113	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Ailuropoda melanoleuca].	41.22	296	165	4	3	293	4	295	2e-62	222
tr:A0A0D3SK03_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJS25006.1};	40.13	304	167	4	1	293	1	300	2e-62	222
rs:WP_035418819	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. JCM 19045].	39.72	287	158	4	6	292	7	278	2e-62	210
tr:S7ZE44_PENO1	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPS26961.1};	43.30	291	158	3	3	290	2	288	2e-62	222
rs:WP_028503992	methenyltetrahydrofolate cyclohydrolase [Microbacterium sp. URHA0036].	41.67	300	160	7	1	293	1	292	2e-62	211
rs:WP_030451393	methenyltetrahydrofolate cyclohydrolase [Herbidospora cretacea].	41.30	293	157	6	1	291	1	280	2e-62	210
rs:WP_008260055	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium].	40.89	291	161	4	1	291	1	280	2e-62	210
tr:A0A0D3SWI8_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJS29948.1};	40.46	304	166	4	1	293	1	300	2e-62	222
rs:WP_020806953	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus gasseri].	42.76	290	152	6	4	292	3	279	2e-62	210
rs:WP_047259053	methenyltetrahydrofolate cyclohydrolase [Corynebacterium uterequi].	42.47	292	154	4	1	292	1	278	2e-62	210
rs:WP_031514861	methenyltetrahydrofolate cyclohydrolase [Desulfotomaculum alkaliphilum].	40.49	284	157	3	3	286	2	273	2e-62	210
rs:WP_009394595	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces sp. oral taxon 171].	38.93	298	169	6	2	293	8	298	2e-62	211
rs:NP_955823	C-1-tetrahydrofolate synthase, cytoplasmic [Danio rerio].	43.39	295	158	4	1	290	1	291	2e-62	222
rs:XP_012721110	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Fundulus heteroclitus].	47.90	238	117	3	63	294	3	239	2e-62	209
tr:A0A094E570_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY42252.1};	40.54	296	169	3	1	293	171	462	2e-62	223
tr:A0A093YVD2_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY09001.1};	40.54	296	169	3	1	293	172	463	2e-62	223
rs:WP_033188718	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Rhodococcus].	39.10	289	158	3	1	289	14	284	2e-62	210
rs:WP_031551651	5,10-methylene-tetrahydrofolate cyclohydrolase [Gemella sanguinis].	41.96	286	153	5	5	289	3	276	3e-62	210
rs:WP_019972996	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium sp. 141].	42.91	289	148	5	1	286	1	275	3e-62	210
rs:WP_006916206	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus coleohominis].	41.78	292	157	5	3	292	2	282	3e-62	210
rs:WP_036943795	5,10-methylene-tetrahydrofolate cyclohydrolase [Pseudobacteroides cellulosolvens].	41.38	290	154	4	5	293	6	280	3e-62	210
rs:WP_020575653	5,10-methylene-tetrahydrofolate dehydrogenase [Actinopolymorpha alba].	40.89	291	161	5	2	292	3	282	3e-62	210
rs:WP_041528356	methenyltetrahydrofolate cyclohydrolase [Paracoccus aminophilus].	44.06	286	152	3	6	291	1	278	3e-62	210
tr:I0S352_MYCPH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.26	286	158	4	1	286	1	276	3e-62	210
rs:WP_007391876	5,10-methylene-tetrahydrofolate dehydrogenase [Megasphaera sp. UPII 135-E].	38.73	284	162	3	4	287	2	273	3e-62	210
rs:WP_007202958	5,10-methylene-tetrahydrofolate dehydrogenase [Fictibacillus macauensis].	40.28	288	157	3	5	292	6	278	3e-62	210
rs:XP_003865900	Mis12 mitochondrial C1-tetrahydrofolate synthase precursor [Candida orthopsilosis Co 90-125].	43.71	302	153	3	1	289	28	325	3e-62	222
tr:F2QZU6_PICP7	SubName: Full=ADE3 protein {ECO:0000313|EMBL:CCA40924.1}; EC=6.3.4.3 {ECO:0000313|EMBL:CCA40924.1};	38.91	293	170	4	6	293	5	293	3e-62	211
rs:WP_045258163	methenyltetrahydrofolate cyclohydrolase [Microbacterium hydrocarbonoxydans].	41.95	298	162	7	1	293	1	292	3e-62	210
rs:WP_007150091	5,10-methylene-tetrahydrofolate dehydrogenase [Alcanivorax sp. DG881].	38.10	294	167	3	1	293	1	280	3e-62	210
tr:G8BG44_CANPC	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CCE42828.1};	41.22	296	165	4	1	291	1	292	3e-62	222
rs:WP_005447197	5,10-methylene-tetrahydrofolate dehydrogenase [Saccharomonospora azurea].	38.70	292	168	4	1	292	1	281	3e-62	210
rs:WP_014567455	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus johnsonii].	41.61	286	154	4	3	286	2	276	3e-62	210
rs:WP_044111718	bifunctional protein FolD [Mycobacterium canettii].	40.89	291	161	4	1	291	1	280	3e-62	210
rs:WP_029107104	methenyltetrahydrofolate cyclohydrolase [Mycobacterium sp. URHD0025].	42.56	289	149	5	1	286	1	275	3e-62	210
rs:WP_033378176	methenyltetrahydrofolate cyclohydrolase [Corynebacterium lubricantis].	41.24	291	152	6	6	292	9	284	3e-62	210
rs:WP_027763291	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. CNS606].	39.51	286	163	5	1	286	1	276	3e-62	210
rs:XP_003740156	PREDICTED: bifunctional protein FolD-like [Metaseiulus occidentalis].	42.91	289	149	4	2	288	28	302	3e-62	211
rs:WP_036162683	5,10-methylene-tetrahydrofolate cyclohydrolase [Marinomonas ushuaiensis].	36.86	293	171	2	1	293	1	279	3e-62	210
rs:WP_009954119	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium intracellulare].	40.89	291	161	4	1	291	1	280	3e-62	210
rs:WP_006562680	methenyltetrahydrofolate cyclohydrolase [Oscillochloris trichoides].	39.45	289	165	2	1	289	1	279	3e-62	210
rs:WP_027828651	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus harbinensis].	41.87	289	157	3	5	293	4	281	3e-62	210
sp:FOLD_DESRM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.93	283	158	3	4	286	3	273	3e-62	210
rs:XP_007940472	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Orycteropus afer afer].	41.22	296	165	4	3	293	4	295	3e-62	222
tr:M0QF21_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.86	293	171	2	1	293	1	279	3e-62	210
rs:XP_002069966	GK11804 [Drosophila willistoni].	43.05	295	160	4	3	293	4	294	3e-62	222
rs:XP_002373555	C1 tetrahydrofolate synthase, putative [Aspergillus flavus NRRL3357].	43.34	293	159	3	1	290	104	392	3e-62	223
rs:WP_035963758	methenyltetrahydrofolate cyclohydrolase [Kocuria marina].	40.27	298	167	7	1	293	1	292	3e-62	210
rs:WP_023438496	bifunctional 5,10-methylene-tetrahydrofolatedehydrogenase/ 5,10-methylene-tetrahydrofolatecyclohydrolase [Clostridium tetani].	39.07	279	159	3	6	284	5	272	4e-62	209
tr:F2S8Y3_TRIT1	SubName: Full=Formate-tetrahydrofolate ligase {ECO:0000313|EMBL:EGE00033.1};	43.20	294	158	5	1	290	87	375	4e-62	222
sp:FOLD_ACHLI	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.93	280	142	3	5	284	2	266	4e-62	209
rs:WP_020858778	bifunctional protein FolD [SAR86 cluster bacterium SAR86B].	39.86	291	160	4	1	291	1	276	4e-62	209
tr:Q28BS7_XENTR	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase {ECO:0000313|EMBL:CAJ82471.1};	42.28	298	163	4	1	293	1	294	4e-62	222
rs:WP_015294356	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium canettii].	41.10	292	161	4	1	292	1	281	4e-62	209
rs:XP_005047760	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Ficedula albicollis].	43.10	297	158	5	3	293	4	295	4e-62	222
rs:WP_006364223	tetrahydrofolate dehydrogenase [Gemella sanguinis].	41.96	286	153	5	5	289	3	276	4e-62	209
rs:WP_018050659	hypothetical protein [SAR324 cluster bacterium SCGC AB-629-J17].	39.86	291	168	3	1	291	1	284	4e-62	210
tr:A0A028JWS0_TRIRU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EZG08637.1};	43.20	294	158	5	1	290	86	374	4e-62	222
rs:WP_006210996	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus vortex].	38.64	295	164	5	1	293	1	280	4e-62	209
rs:WP_004006051	5,10-methylene-tetrahydrofolate dehydrogenase [Rothia dentocariosa].	41.55	296	158	7	4	292	3	290	4e-62	210
tr:A0A084ATD1_STACH	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KEY68560.1};	41.84	294	155	5	1	286	1	286	4e-62	221
rs:XP_003233082	C1 tetrahydrofolate synthase [Trichophyton rubrum CBS 118892].	43.20	294	158	5	1	290	86	374	4e-62	222
tr:J3S6Y4_CORMI	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:AFK23399.1};	42.37	295	154	5	1	288	140	425	4e-62	223
rs:WP_007386647	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sviceus].	38.97	290	163	2	3	292	4	279	4e-62	209
rs:XP_012216703	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Linepithema humile].	42.47	292	160	4	5	292	9	296	4e-62	221
tr:A0A0C6BLE2_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJR82730.1};	40.13	304	167	4	1	293	1	300	4e-62	221
tr:X1TB64_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_S00176 {ECO:0000313|EMBL:GAI77269.1}; Flags: Fragment;	44.49	227	126	0	1	227	1	227	4e-62	207
rs:WP_041838053	5,10-methylene-tetrahydrofolate cyclohydrolase [Actinosynnema mirum].	38.46	286	162	2	1	286	1	272	4e-62	209
tr:C0NAW3_AJECG	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:EEH10804.1};	42.12	292	157	3	1	290	47	328	4e-62	222
rs:WP_026004340	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	40.85	284	158	5	1	284	1	274	4e-62	209
rs:WP_022920349	5,10-methylene-tetrahydrofolate dehydrogenase [Ornithinimicrobium pekingense].	39.04	292	165	5	1	292	1	279	4e-62	209
tr:A0A094G343_9PEZI	RecName: Full=Eukaryotic translation initiation factor 3 subunit I {ECO:0000256|SAAS:SAAS00003572};	40.88	296	168	3	1	293	497	788	4e-62	224
rs:WP_014385733	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium avium complex (MAC)].	40.89	291	161	4	1	291	1	280	5e-62	209
rs:WP_032929036	bifunctional protein FolD [Mesorhizobium loti].	41.44	292	160	5	6	294	10	293	5e-62	210
sp:FOLD_ROSS1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.69	293	155	2	1	293	1	283	5e-62	209
tr:A0A0C9XUG0_9AGAR	SubName: Full=Unplaced genomic scaffold K443scaffold_6, whole genome shotgun sequence {ECO:0000313|EMBL:KIK08626.1};	42.71	295	158	5	2	289	28	318	5e-62	221
rs:NP_001008007	mthfd1 protein [Xenopus (Silurana) tropicalis].	42.28	298	163	4	1	293	1	294	5e-62	221
rs:XP_005561523	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Macaca fascicularis].	41.89	296	162	5	3	293	112	402	5e-62	222
rs:WP_016810421	bifunctional protein FolD [Salinispora arenicola].	37.80	291	167	2	1	291	1	277	5e-62	209
tr:A0A094E621_9PEZI	RecName: Full=Eukaryotic translation initiation factor 3 subunit I {ECO:0000256|SAAS:SAAS00003572};	40.88	296	168	3	1	293	652	943	5e-62	224
rs:WP_007514250	5,10-methylene-tetrahydrofolate dehydrogenase [Frankia sp. CN3].	40.56	286	155	3	1	286	1	271	5e-62	210
rs:XP_537476	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Canis lupus familiaris].	40.88	296	166	4	3	293	4	295	5e-62	221
rs:WP_018146580	5,10-methylene-tetrahydrofolate dehydrogenase [Henriciella marina].	43.45	290	152	5	3	289	2	282	5e-62	210
rs:WP_008928508	5,10-methylene-tetrahydrofolate dehydrogenase [Alcanivorax hongdengensis].	39.12	294	164	4	1	293	1	280	5e-62	209
rs:WP_027496398	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Rhodococcus].	40.75	292	162	4	1	292	1	281	5e-62	209
rs:WP_036453769	methenyltetrahydrofolate cyclohydrolase [Mycobacterium sp. TKK-01-0059].	40.89	291	161	4	1	291	1	280	5e-62	209
rs:XP_011691681	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Wasmannia auropunctata].	42.81	292	159	4	5	292	9	296	5e-62	221
rs:WP_032400121	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	41.10	292	161	4	1	292	1	281	5e-62	209
rs:XP_005343281	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Microtus ochrogaster].	41.89	296	163	4	3	293	4	295	5e-62	221
rs:WP_005962126	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces cardiffensis].	39.53	296	165	6	3	292	9	296	5e-62	210
rs:WP_010160059	5,10-methylene-tetrahydrofolate dehydrogenase [SAR86 cluster bacterium SAR86D].	39.86	291	160	4	1	291	1	276	5e-62	209
rs:XP_006142460	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Tupaia chinensis].	43.20	294	156	6	3	290	4	292	5e-62	221
tr:A0A096M8K5_POEFO	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPFOP00000027746};	43.56	303	157	6	1	293	1	299	5e-62	221
rs:WP_037188179	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	40.55	291	162	4	1	291	1	280	5e-62	209
tr:W6Q6I2_PENRO	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:CDM31955.1};	43.00	293	160	3	1	290	76	364	5e-62	222
rs:WP_028680114	5,10-methylene-tetrahydrofolate cyclohydrolase [Salinispora arenicola].	37.80	291	167	2	1	291	1	277	5e-62	209
rs:XP_007873786	hypothetical protein PNEG_01815 [Pneumocystis murina B123].	40.75	292	166	3	3	291	11	298	5e-62	221
rs:XP_011691672	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Wasmannia auropunctata].	42.81	292	159	4	5	292	24	311	5e-62	221
sp:FOLD2_RHILO	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.10	292	161	5	6	294	10	293	5e-62	210
rs:XP_012679411	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Clupea harengus].	42.42	297	160	5	3	293	24	315	5e-62	221
rs:WP_007167977	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium parascrofulaceum].	40.41	292	163	4	1	292	1	281	6e-62	209
tr:M4A5C7_XIPMA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSXMAP00000009671}; Flags: Fragment;	41.41	297	161	6	3	291	33	324	6e-62	211
rs:WP_035763468	methenyltetrahydrofolate cyclohydrolase [Clostridium butyricum].	40.48	289	161	2	3	291	2	279	6e-62	209
rs:WP_009369891	5,10-methylene-tetrahydrofolate dehydrogenase [Megasphaera genomosp. type_1].	40.28	283	157	3	4	286	2	272	6e-62	209
rs:WP_014546189	5,10-methylene-tetrahydrofolate dehydrogenase [Fibrobacter succinogenes].	39.86	286	157	3	1	286	1	271	6e-62	209
tr:A0A059JF84_9EURO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDB26546.1};	42.86	294	159	5	1	290	87	375	6e-62	221
rs:XP_012679413	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X3 [Clupea harengus].	42.42	297	160	5	3	293	24	315	6e-62	221
tr:A0A093VJ94_PENMA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFX50049.1};	42.62	298	151	5	1	290	1	286	6e-62	222
tr:M2WIP3_9NOCA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.24	291	160	4	1	291	1	280	6e-62	209
rs:WP_037182911	5,10-methylene-tetrahydrofolate cyclohydrolase [Rhodococcus fascians].	39.10	289	158	3	1	289	2	272	6e-62	209
sp:FOLD1_SALAI	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.80	291	167	2	1	291	1	277	6e-62	209
rs:XP_007324587	hypothetical protein SERLADRAFT_454136 [Serpula lacrymans var. lacrymans S7.9].	42.76	297	160	4	1	291	6	298	6e-62	221
rs:WP_007623293	bifunctional protein FolD [Gordonia soli].	39.93	293	165	4	1	293	1	282	6e-62	209
rs:WP_036761468	methenyltetrahydrofolate cyclohydrolase, partial [Paracoccus versutus].	45.56	259	134	2	34	292	5	256	6e-62	209
rs:WP_029138015	methenyltetrahydrofolate cyclohydrolase [Nakamurella lactea].	39.86	286	159	5	1	286	1	273	6e-62	209
tr:E9GV17_DAPPU	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EFX76587.1};	47.72	241	118	3	56	292	2	238	6e-62	218
rs:XP_012679412	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Clupea harengus].	42.42	297	160	5	3	293	24	315	6e-62	221
rs:WP_014944260	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Chlamydia psittaci].	47.70	239	123	2	54	291	2	239	6e-62	207
rs:XP_010974953	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Camelus dromedarius].	40.54	296	166	5	3	293	4	294	7e-62	221
tr:F6XNH4_CANFA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCAFP00000023552}; Flags: Fragment;	40.88	296	166	4	3	293	33	324	7e-62	221
rs:WP_037472852	methenyltetrahydrofolate cyclohydrolase, partial [Sphingobium sp. ba1].	46.33	259	132	3	34	292	1	252	7e-62	208
rs:XP_009004400	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Callithrix jacchus].	40.88	296	166	4	3	293	4	295	7e-62	221
rs:WP_022867611	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces vaccimaxillae].	41.22	296	161	6	2	291	8	296	7e-62	209
tr:A0A024JVJ9_9MYCO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.41	292	163	4	1	292	26	306	7e-62	210
tr:G7PAI5_MACFA	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EHH63703.1};	41.55	296	163	5	3	293	4	294	7e-62	221
rs:WP_024448985	methenyltetrahydrofolate cyclohydrolase [Mycobacterium iranicum].	41.38	290	160	4	1	290	4	283	7e-62	209
rs:WP_015739265	5,10-methylene-tetrahydrofolate dehydrogenase [Ammonifex degensii].	42.66	286	152	4	3	288	2	275	7e-62	209
rs:WP_046316346	methenyltetrahydrofolate cyclohydrolase [Mycobacterium sp. UM_Kg1].	41.61	286	156	5	1	286	1	275	7e-62	209
rs:WP_029199366	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus alginolyticus].	38.44	294	164	4	1	292	1	279	7e-62	209
rs:WP_007128428	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bacillales].	39.66	295	161	5	1	293	1	280	7e-62	209
tr:F7BMX8_MACMU	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:AFE78358.1}; SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000001759};	41.55	296	163	5	3	293	4	294	7e-62	221
rs:WP_029025414	5,10-methylene-tetrahydrofolate cyclohydrolase [Salinispora arenicola].	37.80	291	167	2	1	291	1	277	7e-62	209
rs:XP_009775068	PREDICTED: bifunctional protein FolD 1, mitochondrial-like [Nicotiana sylvestris].	38.23	293	175	2	2	292	56	344	7e-62	211
rs:XP_008470605	PREDICTED: LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic [Diaphorina citri].	42.23	296	163	4	2	293	43	334	7e-62	219
rs:WP_018586045	bifunctional protein FolD [Salinispora arenicola].	37.80	291	167	2	1	291	1	277	7e-62	209
rs:WP_009577005	5,10-methylene-tetrahydrofolate dehydrogenase [gamma proteobacterium IMCC3088].	38.91	293	165	2	1	293	1	279	8e-62	209
tr:F1PYV1_CANFA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCAFP00000023570}; Flags: Fragment;	40.88	296	166	4	3	293	22	313	8e-62	221
tr:C8VIX6_EMENI	SubName: Full=TPA: Aspergillus nidulans FGSC A4 chromosome VI {ECO:0000313|EMBL:CBF83595.1};	42.66	293	161	3	1	290	93	381	8e-62	221
tr:A0A0A2JDJ0_PENEN	SubName: Full=Formate-tetrahydrofolate ligase, FTHFS {ECO:0000313|EMBL:KGO52861.1};	42.66	293	161	3	1	290	1	289	8e-62	221
tr:X1RCL3_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_C04594 {ECO:0000313|EMBL:GAI64756.1}; Flags: Fragment;	43.03	251	136	1	4	254	3	246	8e-62	207
rs:WP_029118730	5,10-methylene-tetrahydrofolate cyclohydrolase [Mycobacterium sp. UNC410CL29Cvi84].	38.01	292	167	2	1	292	1	278	8e-62	209
rs:XP_011644473	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Pogonomyrmex barbatus].	43.49	292	157	4	5	292	35	322	8e-62	221
rs:XP_695978	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Danio rerio].	42.76	297	159	5	3	293	25	316	8e-62	221
rs:WP_046203798	methenyltetrahydrofolate cyclohydrolase [Corynebacterium argentoratense].	41.98	293	159	4	1	293	1	282	8e-62	209
rs:WP_020217842	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora arenicola].	37.80	291	167	2	1	291	1	277	8e-62	209
tr:F7BGW5_MACMU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000001760};	41.55	296	163	5	3	293	4	294	8e-62	221
rs:NP_001189703	amino acid dehydrogenase family protein [Arabidopsis thaliana].	43.53	255	138	2	5	257	65	315	9e-62	210
rs:WP_031687959	methenyltetrahydrofolate cyclohydrolase [Mycobacterium tuberculosis].	40.55	291	162	4	1	291	1	280	9e-62	209
rs:WP_036434299	methenyltetrahydrofolate cyclohydrolase [Mycobacterium mageritense].	43.25	289	147	5	1	286	1	275	9e-62	209
rs:WP_007555516	5,10-methylene-tetrahydrofolate dehydrogenase [Dialister micraerophilus].	41.35	266	144	3	5	270	2	255	9e-62	209
rs:XP_009831853	hypothetical protein H257_07865 [Aphanomyces astaci].	37.28	287	165	4	2	284	5	280	9e-62	209
rs:WP_028050007	methenyltetrahydrofolate cyclohydrolase [Cellulomonas sp. URHD0024].	42.03	295	162	6	1	291	1	290	9e-62	209
rs:WP_038627768	methenyltetrahydrofolate cyclohydrolase [Corynebacterium sp. ATCC 6931].	40.48	294	158	5	1	291	1	280	9e-62	209
rs:XP_005044539	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Ficedula albicollis].	46.74	261	132	3	3	257	49	308	9e-62	213
tr:S7N5W3_MYOBR	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:EPQ12559.1};	41.55	296	164	4	3	293	4	295	9e-62	220
tr:A0A096NVK8_PAPAN	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPANP00000017083};	41.55	296	163	5	3	293	4	294	9e-62	221
rs:WP_046361718	methenyltetrahydrofolate cyclohydrolase [Mycobacterium obuense].	41.87	289	152	5	1	286	4	279	9e-62	209
rs:WP_019860020	MULTISPECIES: bifunctional protein FolD [Mesorhizobium].	40.75	292	162	5	6	294	10	293	9e-62	209
rs:WP_031259483	methenyltetrahydrofolate cyclohydrolase, partial [Mesorhizobium sp. LNHC252B00].	39.86	291	166	4	6	294	10	293	1e-61	209
rs:WP_013530353	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium ciceri].	39.86	291	166	4	6	294	10	293	1e-61	209
rs:WP_026429531	methenyltetrahydrofolate cyclohydrolase [Actinobaculum schaalii].	40.07	297	164	6	1	291	1	289	1e-61	211
tr:A0A084FUE4_9PEZI	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KEZ38706.1};	41.16	294	159	4	1	291	1	283	1e-61	220
rs:WP_031702272	bifunctional protein FolD [Mycobacterium africanum].	40.55	291	162	4	1	291	1	280	1e-61	208
rs:WP_003905054	bifunctional protein FolD [Mycobacterium tuberculosis].	40.55	291	162	4	1	291	1	280	1e-61	208
rs:WP_022105626	bifunctional protein FolD [Dialister sp. CAG:486].	39.45	289	163	3	3	291	2	278	1e-61	208
tr:A0A076D1F8_MYCTX	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:AIH86315.1}; Flags: Fragment;	40.55	291	162	4	1	291	1	280	1e-61	208
rs:WP_037163900	5,10-methylene-tetrahydrofolate cyclohydrolase [Rhodococcus fascians].	38.75	289	159	3	1	289	2	272	1e-61	209
tr:A0A084W7B5_9DIPT	SubName: Full=AGAP002830-PA-like protein {ECO:0000313|EMBL:KFB46109.1};	41.64	293	163	4	3	291	116	404	1e-61	221
rs:XP_004179096	hypothetical protein TBLA_0B07610 [Tetrapisispora blattae CBS 6284].	40.94	298	159	5	4	292	12	301	1e-61	220
rs:WP_031735955	methenyltetrahydrofolate cyclohydrolase [Mycobacterium tuberculosis].	40.55	291	162	4	1	291	1	280	1e-61	208
rs:XP_011616924	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X3 [Takifugu rubripes].	44.92	256	131	4	41	291	5	255	1e-61	208
rs:XP_005874095	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Myotis brandtii].	41.55	296	164	4	3	293	4	295	1e-61	220
tr:W7QYI0_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:EWH18434.1};	40.13	304	167	4	1	293	1	300	1e-61	220
rs:XP_008092355	formate-tetrahydrofolate ligase [Colletotrichum graminicola M1.001].	40.88	296	168	3	1	293	1	292	1e-61	220
sp:FOLD_MYCTA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.55	291	162	4	1	291	1	280	1e-61	208
tr:H3G8R8_PHYRM	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:Phyra71311};	40.84	311	157	6	5	293	10	315	1e-61	209
tr:X0SSX9_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_L00509 {ECO:0000313|EMBL:GAF84278.1}; Flags: Fragment;	43.97	257	129	3	1	257	1	242	1e-61	207
rs:WP_018794094	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora arenicola].	37.80	291	167	2	1	291	1	277	1e-61	208
rs:WP_002580552	FolD protein [Clostridium butyricum].	40.14	289	162	2	3	291	2	279	1e-61	208
rs:WP_015797792	5,10-methylene-tetrahydrofolate dehydrogenase [Acidimicrobium ferrooxidans].	40.21	291	165	3	1	291	1	282	1e-61	209
rs:XP_011498558	PREDICTED: LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic [Ceratosolen solmsi marchali].	43.49	292	157	4	5	292	9	296	1e-61	220
rs:XP_005495935	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Zonotrichia albicollis].	42.28	298	123	3	3	294	51	305	1e-61	209
rs:WP_017208898	tetrahydrofolate dehydrogenase [Clostridium beijerinckii].	39.38	292	166	2	3	294	2	282	1e-61	208
rs:WP_042913260	methenyltetrahydrofolate cyclohydrolase [Mycobacterium intracellulare].	40.55	291	162	4	1	291	1	280	1e-61	208
rs:WP_031738897	methenyltetrahydrofolate cyclohydrolase [Mycobacterium tuberculosis].	40.55	291	162	4	1	291	1	280	1e-61	208
rs:WP_045300837	methenyltetrahydrofolate cyclohydrolase [Microbacterium trichothecenolyticum].	41.08	297	166	6	1	293	1	292	1e-61	209
rs:WP_045819427	5,10-methylene-tetrahydrofolate cyclohydrolase [Teredinibacter sp. 1162T.S.0a.05].	38.23	293	167	2	1	293	1	279	1e-61	208
sp:FOLD_CLOB8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.04	292	167	2	3	294	2	282	1e-61	208
rs:WP_021754245	5,10-methylene-tetrahydrofolate dehydrogenase [Leifsonia xyli].	42.95	298	161	6	1	294	1	293	1e-61	209
rs:WP_043621194	methenyltetrahydrofolate cyclohydrolase [Nonomuraea candida].	40.96	293	158	6	1	291	1	280	1e-61	208
rs:WP_019155826	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus massiliosenegalensis].	40.42	287	156	3	5	291	6	277	1e-61	208
rs:WP_005510041	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium amycolatum].	40.48	294	158	5	1	291	1	280	1e-61	208
rs:WP_021765120	tetrahydrofolate dehydrogenase [Leifsonia aquatica].	41.75	297	164	6	1	293	1	292	1e-61	209
rs:WP_036203575	5,10-methylene-tetrahydrofolate cyclohydrolase [Megasphaera elsdenii].	40.21	291	159	4	4	292	2	279	1e-61	208
tr:F6YH42_CALJA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCJAP00000051669};	40.88	296	166	4	3	293	60	351	1e-61	221
rs:WP_036515197	methenyltetrahydrofolate cyclohydrolase [Oceanicaulis sp. HL-87].	43.55	287	151	3	3	289	8	283	1e-61	209
rs:WP_007395471	5,10-methylene-tetrahydrofolate dehydrogenase [Psychrobacter sp. 1501(2011)].	39.18	291	166	3	2	292	10	289	1e-61	208
rs:WP_046189796	methenyltetrahydrofolate cyclohydrolase [Mycobacterium arupense].	41.61	286	156	5	1	286	1	275	1e-61	208
rs:WP_045511584	5,10-methylene-tetrahydrofolate cyclohydrolase [bacterium UASB14].	40.82	294	158	4	1	293	1	279	1e-61	208
rs:WP_017204961	bifunctional protein FolD [Mycobacterium abscessus].	41.78	292	159	4	1	292	1	281	1e-61	208
tr:A0A0A9DET3_ARUDO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:JAD85183.1};	43.85	260	140	2	34	291	9	264	1e-61	208
rs:WP_031625381	methenyltetrahydrofolate cyclohydrolase, partial [Salmonella enterica].	54.23	201	82	3	89	289	1	191	1e-61	205
rs:XP_001101708	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform 1 [Macaca mulatta].	41.55	296	163	5	3	293	112	402	1e-61	221
rs:WP_014758787	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Thermoanaerobacterium].	38.06	289	163	4	5	293	2	274	1e-61	208
rs:XP_003171389	C-1-tetrahydrofolate synthase [Microsporum gypseum CBS 118893].	42.52	294	160	5	1	290	1	289	1e-61	220
rs:XP_006891860	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Elephantulus edwardii].	41.22	296	165	4	3	293	4	295	1e-61	220
rs:WP_020413159	5,10-methylene-tetrahydrofolate dehydrogenase [Microbulbifer variabilis].	38.10	294	167	3	1	293	1	280	1e-61	208
rs:WP_042492368	methenyltetrahydrofolate cyclohydrolase [Weissella hellenica].	43.34	293	150	7	3	290	2	283	1e-61	209
rs:WP_039143944	methenyltetrahydrofolate cyclohydrolase [Lactobacillus fructivorans].	42.66	286	149	6	4	286	3	276	1e-61	208
rs:WP_035511909	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus iners].	41.61	286	155	4	5	290	4	277	1e-61	208
rs:WP_027635919	methenyltetrahydrofolate cyclohydrolase [Clostridium butyricum].	40.14	289	162	2	3	291	2	279	2e-61	208
rs:WP_010622080	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus suebicus].	42.47	292	155	5	3	292	2	282	2e-61	208
rs:XP_001499181	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Equus caballus].	40.88	296	166	4	3	293	4	295	2e-61	220
sp:FOLD_ACIC5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.61	293	159	3	1	292	1	279	2e-61	208
rs:XP_007797972	putative c-1-tetrahydrofolate synthase protein [Eutypa lata UCREL1].	42.21	289	160	3	1	286	1	285	2e-61	220
rs:WP_030427503	methenyltetrahydrofolate cyclohydrolase [Allokutzneria albata].	41.44	292	160	5	1	292	4	284	2e-61	208
rs:WP_028183131	bifunctional protein FolD [Salinispora arenicola].	37.80	291	167	2	1	291	1	277	2e-61	208
rs:XP_005149666	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Melopsittacus undulatus].	43.10	297	158	5	3	293	4	295	2e-61	220
rs:WP_042388430	methenyltetrahydrofolate cyclohydrolase [Corynebacterium sp. HFH0082].	40.48	294	158	5	1	291	1	280	2e-61	208
rs:WP_003408216	tetrahydrofolate dehydrogenase [Clostridium butyricum].	40.14	289	162	2	3	291	2	279	2e-61	208
rs:WP_026214421	methenyltetrahydrofolate cyclohydrolase [Nonomuraea coxensis].	39.86	291	164	4	1	291	1	280	2e-61	208
tr:M6S286_LEPIR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.79	281	158	2	15	295	9	275	2e-61	208
rs:WP_015050717	methylenetetrahydrofolate dehydrogenase [Thermacetogenium phaeum].	41.64	293	157	5	1	290	1	282	2e-61	208
tr:R9XIV3_ASHAC	SubName: Full=AaceriACL121Cp {ECO:0000313|EMBL:AGO13457.1};	41.44	292	164	3	5	293	3	290	2e-61	220
rs:XP_008531461	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Equus przewalskii].	40.88	296	166	4	3	293	4	295	2e-61	220
rs:WP_010131352	5,10-methylene-tetrahydrofolate dehydrogenase [Microbulbifer agarilyticus].	38.10	294	167	3	1	293	1	280	2e-61	208
tr:A0A0C3BKY4_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIM87088.1};	43.30	291	155	4	6	290	15	301	2e-61	220
rs:WP_036353025	methenyltetrahydrofolate cyclohydrolase [Mycobacterium asiaticum].	40.75	292	162	4	1	292	1	281	2e-61	208
tr:A0A096N0H4_PAPAN	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPANP00000005759}; Flags: Fragment;	40.80	299	157	8	3	294	10	295	2e-61	208
rs:XP_012579853	PREDICTED: LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Condylura cristata].	40.88	296	166	4	3	293	37	328	2e-61	220
tr:X6DGW9_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.86	291	166	4	6	294	10	293	2e-61	209
rs:WP_029028860	5,10-methylene-tetrahydrofolate cyclohydrolase [Salinispora arenicola].	37.80	291	167	2	1	291	1	277	2e-61	208
rs:WP_007391266	5,10-methylene-tetrahydrofolate dehydrogenase [Megasphaera sp. UPII 199-6].	39.93	283	158	3	4	286	2	272	2e-61	207
rs:WP_032383970	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	40.41	292	163	4	1	292	1	281	2e-61	208
tr:A0A0A1NJC5_9FUNG	SubName: Full=Putative C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:CEI91858.1};	45.04	242	126	3	1	239	1	238	2e-61	207
rs:XP_003376453	c-1-tetrahydrofolate synthase, cytoplasmic [Trichinella spiralis].	43.92	296	153	6	3	293	2	289	2e-61	219
rs:WP_028848806	methenyltetrahydrofolate cyclohydrolase [Thermocrispum agreste].	41.55	284	155	4	1	284	1	273	2e-61	208
rs:XP_002737032	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Saccoglossus kowalevskii].	43.71	302	149	5	1	291	5	296	2e-61	219
rs:XP_010601307	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Fukomys damarensis].	41.89	296	163	4	3	293	4	295	2e-61	219
rs:WP_039598310	5,10-methylene-tetrahydrofolate cyclohydrolase [Ralstonia sp. A12].	39.24	288	161	2	5	292	4	277	2e-61	207
rs:WP_039913552	5,10-methylene-tetrahydrofolate cyclohydrolase [Cellvibrio mixtus].	38.98	295	164	3	1	293	1	281	2e-61	208
rs:XP_006973213	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Peromyscus maniculatus bairdii].	41.55	296	164	4	3	293	4	295	2e-61	219
rs:XP_007985145	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Chlorocebus sabaeus].	41.55	296	163	5	3	293	112	402	2e-61	220
rs:WP_043535950	methenyltetrahydrofolate cyclohydrolase [Actinomyces sp. MS2].	41.02	295	160	6	3	291	9	295	2e-61	208
rs:WP_032371024	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	40.41	292	163	4	1	292	1	281	2e-61	208
tr:T1JKV3_STRMM	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:SMAR014483-PA};	43.43	297	157	5	3	293	6	297	2e-61	219
rs:WP_022798851	5,10-methylene-tetrahydrofolate dehydrogenase [Thermus islandicus].	42.31	286	149	4	4	289	5	274	2e-61	207
tr:A0A084Q8M0_9HYPO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFA60305.1};	40.83	289	157	4	1	286	1	278	2e-61	219
rs:WP_027056184	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium loti].	39.52	291	167	4	6	294	10	293	2e-61	208
rs:WP_023974711	MULTISPECIES: tetrahydrofolate dehydrogenase [Clostridium].	39.04	292	167	2	3	294	2	282	2e-61	207
rs:WP_007025041	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Actinomycetales].	39.59	293	166	4	1	293	1	282	2e-61	207
rs:WP_036398226	methenyltetrahydrofolate cyclohydrolase [Mycobacterium kansasii].	41.02	295	159	5	1	291	1	284	2e-61	207
tr:A0A0C2X600_AMAMU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIL69752.1};	41.36	295	163	4	3	291	5	295	2e-61	208
rs:WP_023771358	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Mesorhizobium].	40.41	292	163	5	6	294	10	293	2e-61	208
rs:XP_003301935	hypothetical protein PTT_13570 [Pyrenophora teres f. teres 0-1].	41.24	291	160	3	1	289	1	282	2e-61	219
rs:XP_006864627	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Chrysochloris asiatica].	41.55	296	164	4	3	293	4	295	2e-61	219
rs:XP_005491864	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Zonotrichia albicollis].	42.76	297	159	5	3	293	4	295	2e-61	219
rs:XP_007005659	hypothetical protein TREMEDRAFT_32433 [Tremella mesenterica DSM 1558].	41.45	304	160	6	3	292	73	372	2e-61	220
rs:WP_020310362	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Megasphaera].	40.21	291	159	4	4	292	2	279	2e-61	207
rs:WP_034981332	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus sp. wkB10].	38.97	290	165	3	3	292	2	279	2e-61	207
rs:WP_027033630	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium loti].	40.07	292	164	5	6	294	10	293	2e-61	208
tr:W2KJI2_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETL85391.1};	40.74	297	157	4	4	289	3	291	2e-61	208
rs:XP_009099922	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Serinus canaria].	42.76	297	159	5	3	293	4	295	2e-61	219
rs:WP_005443433	5,10-methylene-tetrahydrofolate dehydrogenase [Saccharomonospora azurea].	38.36	292	169	4	1	292	1	281	2e-61	207
tr:G2WET2_YEASK	SubName: Full=K7_Ade3p {ECO:0000313|EMBL:GAA23575.1};	39.80	304	168	4	1	293	1	300	2e-61	219
rs:WP_023646908	5,10-methylene-tetrahydrofolate dehydrogenase [actinobacterium LLX17].	41.98	293	160	5	1	293	1	283	2e-61	207
rs:XP_005012868	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Anas platyrhynchos].	45.63	263	136	3	3	259	45	306	3e-61	212
rs:WP_046469786	methenyltetrahydrofolate cyclohydrolase [Allosalinactinospora lopnorensis].	42.12	292	158	5	1	292	1	281	3e-61	207
rs:XP_011159472	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Solenopsis invicta].	42.47	292	160	4	5	292	23	310	3e-61	219
tr:A0A0D6HCP4_MYCSM	SubName: Full=Bifunctional protein: methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD {ECO:0000313|EMBL:CKH30119.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CKH30119.1};	41.32	288	158	4	6	293	9	285	3e-61	207
rs:WP_031576355	hypothetical protein [Proteiniclasticum ruminis].	39.79	284	160	2	3	286	2	274	3e-61	207
tr:A0A091EZ44_CORBR	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFO61867.1}; Flags: Fragment;	42.91	296	158	5	4	293	1	291	3e-61	219
rs:XP_004682138	PREDICTED: LOW QUALITY PROTEIN: c-1-tetrahydrofolate synthase, cytoplasmic [Condylura cristata].	40.88	296	166	4	3	293	63	354	3e-61	220
rs:WP_022677267	5,10-methylene-tetrahydrofolate dehydrogenase [Novosphingobium sp. B-7].	45.17	290	152	3	3	292	2	284	3e-61	207
rs:WP_019481982	MULTISPECIES: hypothetical protein [Arthrobacter].	39.39	297	167	6	2	292	4	293	3e-61	208
rs:WP_036414420	methenyltetrahydrofolate cyclohydrolase [Mycobacterium gastri].	40.07	292	164	4	1	291	1	282	3e-61	207
rs:XP_011159473	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Solenopsis invicta].	42.47	292	160	4	5	292	9	296	3e-61	219
rs:WP_031887367	methenyltetrahydrofolate cyclohydrolase, partial [Staphylococcus aureus].	44.26	235	126	2	1	235	1	230	3e-61	206
tr:G2GXG9_9ENTR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.55	222	101	2	70	291	43	253	3e-61	207
rs:WP_017828350	5,10-methylene-tetrahydrofolate dehydrogenase [Microbacterium sp. UCD-TDU].	41.89	296	161	7	1	291	1	290	3e-61	207
tr:C6WFU2_ACTMD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.38	284	161	2	3	286	5	274	3e-61	207
rs:WP_040632828	methenyltetrahydrofolate cyclohydrolase [Mycobacterium phlei].	41.05	285	158	4	6	290	3	277	3e-61	207
rs:WP_029116686	methenyltetrahydrofolate cyclohydrolase [Mycobacterium sp. URHB0044].	41.61	286	157	4	1	286	4	279	3e-61	207
rs:WP_027212633	methenyltetrahydrofolate cyclohydrolase [Burkholderia sp. WSM2232].	44.67	291	154	3	3	293	2	285	3e-61	207
rs:XP_004477330	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Dasypus novemcinctus].	41.55	296	164	4	3	293	4	295	3e-61	219
rs:XP_005399187	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Chinchilla lanigera].	41.55	296	164	4	3	293	4	295	3e-61	219
rs:WP_018588401	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora arenicola].	37.46	291	168	2	1	291	1	277	3e-61	207
rs:WP_022229405	bifunctional protein FolD, partial [Firmicutes bacterium CAG:41].	53.09	194	81	2	96	289	1	184	3e-61	204
rs:WP_033521727	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium merycicum].	40.41	292	165	5	6	293	5	291	3e-61	207
rs:WP_025361237	methenyltetrahydrofolate cyclohydrolase [Kutzneria albida].	40.61	293	163	5	1	293	1	282	3e-61	207
rs:WP_027894905	5,10-methylene-tetrahydrofolate cyclohydrolase [Megasphaera elsdenii].	39.86	291	160	4	4	292	2	279	3e-61	207
sp:FOLD_MYCBO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.55	291	162	4	1	291	1	280	3e-61	207
rs:WP_025103804	methenyltetrahydrofolate cyclohydrolase [Microbacterium paraoxydans].	41.28	298	164	7	1	293	1	292	3e-61	207
rs:NP_001080574	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase [Xenopus laevis].	42.62	298	162	4	1	293	1	294	3e-61	219
rs:WP_043806744	methenyltetrahydrofolate cyclohydrolase [Rhodococcus triatomae].	40.89	291	161	4	1	291	4	283	3e-61	207
rs:WP_033213383	methenyltetrahydrofolate cyclohydrolase [Kitasatospora phosalacinea].	41.92	291	158	5	1	291	1	280	3e-61	207
rs:XP_012051394	methylenetetrahydrofolate dehydrogenase (NADP) [Cryptococcus neoformans var. grubii H99].	40.13	304	164	6	2	291	74	373	3e-61	219
tr:A0A066X7T4_COLSU	SubName: Full=Putative formate-tetrahydrofolate ligase {ECO:0000313|EMBL:KDN63709.1};	40.54	296	169	3	1	293	1	292	3e-61	219
rs:WP_033433908	methenyltetrahydrofolate cyclohydrolase [Saccharothrix syringae].	41.30	293	161	5	1	293	1	282	4e-61	207
rs:XP_005520117	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Pseudopodoces humilis].	42.76	297	159	5	3	293	4	295	4e-61	219
rs:XP_011725926	PREDICTED: LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic [Macaca nemestrina].	41.55	296	163	5	3	293	210	500	4e-61	220
rs:XP_004409418	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Odobenus rosmarus divergens].	40.54	296	167	4	3	293	4	295	4e-61	219
tr:A0A0C6D944_YEASX	SubName: Full=Ade3p {ECO:0000313|EMBL:AJS02946.1};	40.13	304	167	4	1	293	1	300	4e-61	219
rs:WP_015272810	methylenetetrahydrofolate dehydrogenase [Liberibacter crescens].	45.17	290	149	5	5	291	4	286	4e-61	207
sp:FOLD_PSYWF	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.64	295	166	3	2	292	5	288	4e-61	207
sp:FOLD_CLOAB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.93	288	162	2	3	290	2	278	4e-61	207
rs:WP_045374649	methenyltetrahydrofolate cyclohydrolase [Mycobacterium kyorinense].	40.41	292	163	4	1	292	1	281	4e-61	207
tr:C0S0U4_PARBP	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEH18890.2};	42.81	292	155	3	1	290	100	381	4e-61	219
rs:WP_015316504	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium australicum].	40.41	292	163	5	6	294	10	293	4e-61	208
rs:WP_037716482	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. AA4].	41.20	284	156	4	1	284	1	273	4e-61	207
rs:WP_023371280	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium kansasii].	41.02	295	159	5	1	291	1	284	4e-61	207
sp:FOLD_HYPNA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	46.33	259	131	4	34	289	30	283	4e-61	207
sp:FOLD_MYCGI	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.61	293	164	4	1	293	4	286	4e-61	207
rs:WP_037595601	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Streptacidiphilus jeojiense].	42.11	285	154	3	6	290	5	278	4e-61	207
rs:WP_027494744	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Rhodococcus].	40.42	287	160	4	6	292	7	282	4e-61	207
tr:U3CS66_CALJA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:JAB22182.1};	40.54	296	167	4	3	293	4	295	4e-61	219
rs:WP_018191848	5,10-methylene-tetrahydrofolate dehydrogenase [Leifsonia sp. 109].	41.61	298	165	6	1	294	1	293	4e-61	207
rs:WP_003543143	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Desulfotomaculum].	40.99	283	155	3	4	286	3	273	4e-61	207
rs:WP_044484059	methenyltetrahydrofolate cyclohydrolase [Mycobacterium tuberculosis].	40.41	292	163	4	1	292	1	281	4e-61	207
rs:WP_029936027	methenyltetrahydrofolate cyclohydrolase [Sphingomonas sp. UNC305MFCol5.2].	43.79	290	154	4	3	291	2	283	4e-61	207
rs:WP_022957427	5,10-methylene-tetrahydrofolate dehydrogenase [Spongiibacter tropicus].	37.76	294	168	3	1	293	1	280	4e-61	207
rs:WP_042539333	methenyltetrahydrofolate cyclohydrolase [Microbacterium sp. MEJ108Y].	40.94	298	165	7	1	293	1	292	4e-61	207
rs:WP_046296215	methenyltetrahydrofolate cyclohydrolase [Mycobacterium sp. UM_Kg17].	40.91	286	158	5	1	286	1	275	4e-61	207
rs:XP_001998322	GI23694 [Drosophila mojavensis].	41.92	291	161	4	1	287	3	289	4e-61	219
rs:WP_038569073	methenyltetrahydrofolate cyclohydrolase [Dermacoccus nishinomiyaensis].	39.86	286	159	5	1	286	1	273	4e-61	207
rs:WP_031715348	bifunctional protein FolD [Mycobacterium tuberculosis].	40.21	291	163	4	1	291	1	280	4e-61	207
rs:WP_039318409	methenyltetrahydrofolate cyclohydrolase [Mycobacterium setense].	41.87	289	151	5	1	286	1	275	4e-61	207
rs:WP_032374061	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	40.42	287	160	4	6	292	7	282	4e-61	207
rs:WP_022503717	bifunctional protein FolD [Mycoplasma sp. CAG:776].	41.81	287	155	3	5	291	3	277	4e-61	207
rs:WP_018809031	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora arenicola].	37.46	291	168	2	1	291	1	277	4e-61	207
rs:WP_035458287	5,10-methylene-tetrahydrofolate cyclohydrolase [Alcanivorax sp. 97CO-5].	37.76	294	168	3	1	293	1	280	4e-61	207
rs:WP_020823460	tetrahydrofolate dehydrogenase [Mycobacterium yongonense].	40.89	291	161	4	1	291	1	280	4e-61	207
rs:WP_029152666	methenyltetrahydrofolate cyclohydrolase [Microbacterium gubbeenense].	41.08	297	166	6	1	293	1	292	4e-61	207
rs:WP_019032574	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora arenicola].	37.46	291	168	2	1	291	1	277	4e-61	207
rs:XP_009901907	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Picoides pubescens].	42.09	297	161	5	3	293	4	295	4e-61	219
tr:A0A061HDI8_BLUGR	SubName: Full=Mitochondrial C1-tetrahydrofolate synthase {ECO:0000313|EMBL:EPQ62700.1};	46.89	241	122	2	54	292	2	238	4e-61	218
rs:WP_014994728	5,10-methylene-tetrahydrofolate dehydrogenase [Alcanivorax dieselolei].	39.32	295	162	5	1	293	1	280	5e-61	207
rs:WP_023870680	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium avium].	40.55	291	162	4	1	291	1	280	5e-61	207
gp:CP000384_1194	methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+) [Mycobacterium sp. MCS]	44.44	252	131	3	39	290	1	243	5e-61	206
tr:A0A094QG65_9ZZZZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGA21289.1};	42.12	292	155	4	1	292	1	278	5e-61	207
rs:WP_046283444	methenyltetrahydrofolate cyclohydrolase [Mycobacterium sp. UM_NZ2].	41.61	286	156	5	1	286	1	275	5e-61	207
rs:WP_042907962	methenyltetrahydrofolate cyclohydrolase [Mycobacterium avium].	40.55	291	162	4	1	291	1	280	5e-61	207
rs:WP_023388278	tetrahydrofolate dehydrogenase [Youngiibacter fragilis].	39.58	288	163	2	4	291	3	279	5e-61	207
rs:XP_011895829	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Cercocebus atys].	44.53	265	140	3	3	261	51	314	5e-61	208
rs:WP_043076560	methenyltetrahydrofolate cyclohydrolase [Mycobacterium immunogenum].	41.10	292	161	4	1	292	1	281	5e-61	207
tr:X1N8N3_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S03198 {ECO:0000313|EMBL:GAI26551.1}; Flags: Fragment;	50.50	202	93	1	92	293	3	197	5e-61	204
rs:WP_028468370	5,10-methylene-tetrahydrofolate cyclohydrolase [Neptunomonas japonica].	38.49	291	165	2	1	291	1	277	5e-61	207
rs:XP_005022720	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Anas platyrhynchos].	41.89	296	163	4	3	293	4	295	5e-61	218
rs:WP_018180781	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia kroppenstedtii].	38.91	293	168	4	1	293	4	285	5e-61	207
rs:WP_046307172	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus apis].	40.69	290	158	4	3	291	2	278	5e-61	207
rs:XP_004837471	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Heterocephalus glaber].	42.23	296	162	4	3	293	4	295	5e-61	218
rs:WP_006732376	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus iners].	41.61	286	155	4	5	290	4	277	5e-61	207
tr:X1S2V0_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_C02269 {ECO:0000313|EMBL:GAI69770.1};	45.36	291	154	5	1	290	1	287	5e-61	207
tr:A0A0A2L5F7_PENIT	SubName: Full=Formate-tetrahydrofolate ligase, FTHFS {ECO:0000313|EMBL:KGO75342.1};	42.32	293	162	3	1	290	1	289	5e-61	218
tr:H2NLI1_PONAB	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|Ensembl:ENSPPYP00000006705};	41.96	286	157	4	3	283	4	285	5e-61	218
rs:WP_013472627	bifunctional protein FolD [Mycobacterium gilvum].	40.61	293	164	4	1	293	4	286	5e-61	207
rs:WP_028327642	methenyltetrahydrofolate cyclohydrolase [Dermatophilus congolensis].	38.70	292	166	5	1	292	1	279	5e-61	207
rs:WP_041523515	5,10-methylene-tetrahydrofolate cyclohydrolase [Gilvimarinus agarilyticus].	39.32	295	162	5	1	293	1	280	5e-61	207
rs:WP_027042602	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. URHC0008].	40.07	292	164	5	6	294	10	293	5e-61	207
rs:WP_045859572	5,10-methylene-tetrahydrofolate cyclohydrolase [Alteromonadaceae bacterium Bs12].	37.54	293	169	2	1	293	1	279	5e-61	206
rs:WP_028189650	5,10-methylene-tetrahydrofolate cyclohydrolase [Salinispora arenicola].	37.80	291	167	2	1	291	1	277	5e-61	206
rs:WP_013893880	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium opportunistum].	40.41	292	163	5	6	294	10	293	5e-61	207
sp:FOLD_MYCA9	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.44	292	160	4	1	292	1	281	5e-61	206
rs:WP_013120568	5,10-methylene-tetrahydrofolate dehydrogenase [Thermincola potens].	41.16	294	159	4	1	292	1	282	5e-61	207
tr:R4MAL4_MYCTX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.21	291	163	4	1	291	1	280	5e-61	206
rs:WP_029262329	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Microbacterium].	41.28	298	164	7	1	293	1	292	5e-61	207
rs:WP_006681414	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces turicensis].	40.34	295	162	6	3	291	9	295	5e-61	207
tr:S2X7G6_9CORY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.48	294	158	5	1	291	37	316	6e-61	208
rs:XP_005898313	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Bos mutus].	40.88	296	166	4	3	293	4	295	6e-61	218
rs:WP_010238013	tetrahydrofolate dehydrogenase [Clostridium arbusti].	39.24	288	164	2	3	290	2	278	6e-61	206
tr:A0A068U4M3_COFCA	SubName: Full=Coffea canephora DH200=94 genomic scaffold, scaffold_11 {ECO:0000313|EMBL:CDP03515.1};	41.58	291	126	2	3	293	9	255	6e-61	206
rs:XP_010736567	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Larimichthys crocea].	43.90	287	152	4	1	282	1	283	6e-61	218
rs:WP_006734582	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus].	41.61	286	155	4	5	290	4	277	6e-61	207
rs:WP_046011445	methenyltetrahydrofolate cyclohydrolase [Microbacterium sp. SA39].	41.55	296	162	7	1	291	1	290	6e-61	207
sp:FOLD3_ARATH	RecName: Full=Bifunctional protein FolD 3, chloroplastic; AltName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase 3; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Flags: Precursor;	40.55	291	131	4	3	291	55	305	6e-61	207
rs:WP_043597337	methenyltetrahydrofolate cyclohydrolase [Frigoribacterium sp. MEB024].	41.08	297	161	5	2	291	15	304	6e-61	207
rs:WP_043371078	methenyltetrahydrofolate cyclohydrolase [Mycobacterium mageritense].	42.21	289	150	5	1	286	1	275	6e-61	206
rs:WP_017204101	5,10-methylene-tetrahydrofolate dehydrogenase [Microbacterium barkeri].	41.22	296	163	7	1	291	1	290	6e-61	207
rs:WP_034629543	methenyltetrahydrofolate cyclohydrolase [Cellulomonas cellasea].	41.08	297	166	5	1	293	1	292	6e-61	207
rs:XP_004624848	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Octodon degus].	41.41	297	163	5	3	293	4	295	6e-61	218
rs:WP_034502708	methenyltetrahydrofolate cyclohydrolase [Actinomyces sp. S6-Spd3].	40.00	295	168	6	3	293	9	298	6e-61	207
rs:WP_034971173	methenyltetrahydrofolate cyclohydrolase [Corynebacterium jeikeium].	43.73	295	148	7	1	291	1	281	6e-61	206
rs:WP_022994968	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Alcanivorax].	38.64	295	164	5	1	293	1	280	6e-61	206
rs:WP_033711559	methenyltetrahydrofolate cyclohydrolase [Mycobacterium sp. MAC_011194_8550].	40.55	291	162	4	1	291	1	280	6e-61	206
rs:WP_009978848	MULTISPECIES: bifunctional protein FolD [Mycobacterium avium complex (MAC)].	40.55	291	162	4	1	291	1	280	6e-61	206
rs:WP_031725621	methenyltetrahydrofolate cyclohydrolase [Mycobacterium tuberculosis].	40.55	291	162	4	1	291	1	280	6e-61	206
tr:F1NMC3_CHICK	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGALP00000019224};	41.55	296	164	4	3	293	4	295	7e-61	218
rs:WP_006736685	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus iners].	41.61	286	155	4	5	290	4	277	7e-61	206
rs:WP_046254576	methenyltetrahydrofolate cyclohydrolase [Mycobacterium chelonae].	43.13	262	139	3	31	292	30	281	7e-61	206
rs:XP_010845098	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Bison bison bison].	40.88	296	166	4	3	293	4	295	7e-61	218
rs:WP_027146156	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. WSM3626].	40.07	292	164	5	6	294	10	293	7e-61	207
rs:WP_037356515	methenyltetrahydrofolate cyclohydrolase [Amycolatopsis orientalis].	41.20	284	156	4	1	284	1	273	7e-61	206
rs:WP_015392828	bifunctional protein FolD [Clostridium saccharoperbutylacetonicum].	39.73	292	165	2	3	294	2	282	7e-61	206
rs:WP_034580756	methenyltetrahydrofolate cyclohydrolase [Clostridium acetobutylicum].	39.93	288	162	2	3	290	2	278	7e-61	206
rs:WP_030096810	methenyltetrahydrofolate cyclohydrolase [Mycobacterium abscessus].	43.13	262	139	3	31	292	30	281	7e-61	206
tr:G3YZM6_9LACO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.61	286	155	4	5	290	15	288	7e-61	207
rs:WP_035767871	methenyltetrahydrofolate cyclohydrolase [Clostridium butyricum].	39.79	289	163	2	3	291	2	279	7e-61	206
rs:WP_026287080	5,10-methylene-tetrahydrofolate cyclohydrolase [Gilvimarinus chinensis].	38.78	294	165	3	1	293	1	280	7e-61	206
rs:WP_007114947	5,10-methylene-tetrahydrofolate dehydrogenase [Enhydrobacter aerosaccus].	38.33	287	169	3	1	286	1	280	7e-61	206
rs:XP_004989928	MTHFD1L protein [Salpingoeca rosetta].	40.67	300	169	4	1	295	1	296	7e-61	218
rs:XP_010582445	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Haliaeetus leucocephalus].	42.42	297	160	5	3	293	4	295	7e-61	218
rs:WP_044088527	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium reuteri].	41.10	292	163	5	6	293	5	291	7e-61	206
rs:NP_001076946	C-1-tetrahydrofolate synthase, cytoplasmic [Bos taurus].	40.88	296	166	4	3	293	4	295	7e-61	218
rs:WP_007426431	5,10-methylene-tetrahydrofolate dehydrogenase [Oceaniovalibus guishaninsula].	42.61	291	160	3	1	291	1	284	7e-61	207
rs:XP_003472395	PREDICTED: LOW QUALITY PROTEIN: c-1-tetrahydrofolate synthase, cytoplasmic [Cavia porcellus].	41.55	296	164	4	3	293	4	295	7e-61	218
tr:H0VMZ6_CAVPO	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCPOP00000011802};	41.55	296	164	4	3	293	4	295	7e-61	218
tr:E0XPS1_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.49	291	172	3	1	291	1	284	7e-61	207
rs:WP_009624077	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfosporosinus sp. OT].	38.03	284	164	3	3	286	2	273	7e-61	206
tr:C8PD95_9LACO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.61	286	155	4	5	290	21	294	7e-61	207
rs:WP_023863173	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium avium].	40.55	291	162	4	1	291	1	280	8e-61	206
rs:XP_006240311	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Rattus norvegicus].	42.01	288	158	4	11	293	18	301	8e-61	218
rs:WP_023767442	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Mesorhizobium].	40.07	292	164	5	6	294	10	293	8e-61	207
rs:WP_036589930	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sophorae].	38.33	287	169	3	1	286	1	280	8e-61	206
rs:XP_011292587	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Musca domestica].	43.58	296	159	4	3	294	4	295	8e-61	218
rs:XP_005183705	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Musca domestica].	43.58	296	159	4	3	294	14	305	8e-61	218
rs:XP_011051725	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Acromyrmex echinatior].	42.81	292	159	4	5	292	9	296	8e-61	218
rs:XP_008111086	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Anolis carolinensis].	41.75	297	162	5	3	293	4	295	8e-61	218
rs:WP_018825644	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora arenicola].	37.11	291	169	2	1	291	1	277	8e-61	206
rs:WP_023868103	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium avium].	40.89	291	161	4	1	291	1	280	8e-61	206
rs:XP_007095267	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Panthera tigris altaica].	40.54	296	167	4	3	293	4	295	8e-61	218
rs:NP_001034392	C-1-tetrahydrofolate synthase, cytoplasmic [Gallus gallus].	41.55	296	164	4	3	293	4	295	8e-61	218
tr:T1P9G4_MUSDO	SubName: Full=FormateHypotheticaltetrahydrofolate ligase {ECO:0000313|EMBL:AFP59978.1};	43.58	296	159	4	3	294	4	295	8e-61	218
rs:XP_004891253	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Heterocephalus glaber].	41.89	296	163	4	3	293	4	295	8e-61	218
tr:X5L718_9MYCO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.91	289	148	5	1	286	9	283	8e-61	206
rs:WP_027061428	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium loti].	39.73	292	165	5	6	294	10	293	8e-61	207
rs:XP_010710317	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Meleagris gallopavo].	41.55	296	164	4	3	293	4	295	8e-61	218
rs:XP_012269660	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X3 [Athalia rosae].	41.44	292	163	4	5	292	9	296	9e-61	218
rs:WP_010021533	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus fructivorans].	42.31	286	150	6	4	286	3	276	9e-61	206
rs:XP_011051724	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Acromyrmex echinatior].	42.81	292	159	4	5	292	24	311	9e-61	218
rs:WP_032368900	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	40.07	287	161	4	6	292	7	282	9e-61	206
rs:WP_013140514	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium longum].	40.89	291	163	5	5	291	4	289	9e-61	206
rs:XP_011292588	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X3 [Musca domestica].	43.58	296	159	4	3	294	37	328	9e-61	218
rs:WP_026886481	methenyltetrahydrofolate cyclohydrolase [Clostridium beijerinckii].	39.04	292	167	2	3	294	2	282	9e-61	206
rs:XP_003987775	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Felis catus].	40.54	296	167	4	3	293	4	295	9e-61	218
rs:WP_035739234	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. TB 26].	39.60	298	168	8	5	297	1	291	9e-61	206
sp:FOLD_ALCBS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.76	294	168	3	1	293	1	280	9e-61	206
rs:WP_047321488	methenyltetrahydrofolate cyclohydrolase [Mycobacterium heraklionense].	41.26	286	157	5	1	286	1	275	9e-61	206
rs:WP_028674625	5,10-methylene-tetrahydrofolate cyclohydrolase [Salinispora arenicola].	37.11	291	169	2	1	291	1	277	9e-61	206
rs:WP_025567600	5,10-methylene-tetrahydrofolate cyclohydrolase [Gammaproteobacteria bacterium SCGC AAA003-E02].	39.59	293	164	4	1	291	1	282	1e-60	206
tr:T1I483_RHOPR	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:RPRC011102-PA}; Flags: Fragment;	43.12	276	144	4	21	293	28	293	1e-60	218
sp:FOLD_CELJU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.88	293	168	2	1	293	1	279	1e-60	206
rs:WP_015291389	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium canettii].	40.21	291	163	4	1	291	1	280	1e-60	206
rs:WP_032382947	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	40.07	287	161	4	6	292	7	282	1e-60	206
rs:WP_032366490	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	40.07	287	161	4	6	292	7	282	1e-60	206
tr:A0A086T7D0_ACRCH	SubName: Full=C-1-tetrahydrofolate synthase-like protein {ECO:0000313|EMBL:KFH45262.1};	40.83	289	157	4	1	286	1	278	1e-60	218
gp:AE000516_3582	methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase [Mycobacterium tuberculosis CDC1551]	40.42	287	160	4	5	291	1	276	1e-60	206
rs:WP_024793433	methenyltetrahydrofolate cyclohydrolase [Tomitella biformata].	41.02	295	155	6	1	291	4	283	1e-60	206
sp:FOLD_MYCA1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.55	291	162	4	1	291	1	280	1e-60	206
tr:A0A0D1IPP9_9MICO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.96	293	159	5	6	291	3	288	1e-60	206
rs:WP_003882331	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium].	41.87	289	151	5	1	286	1	275	1e-60	206
rs:WP_035946826	methenyltetrahydrofolate cyclohydrolase [Knoellia flava].	40.07	292	166	5	1	292	1	283	1e-60	206
rs:WP_031170069	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces durhamensis].	38.83	291	164	2	3	293	4	280	1e-60	206
rs:WP_033104923	methenyltetrahydrofolate cyclohydrolase [Microbacterium profundi].	40.20	296	168	6	1	292	1	291	1e-60	206
rs:XP_001952982	GF17545 [Drosophila ananassae].	43.88	294	156	5	3	293	4	291	1e-60	218
rs:WP_013787960	5,10-methylene-tetrahydrofolate dehydrogenase [Thermoanaerobacterium xylanolyticum].	38.06	289	163	4	5	293	2	274	1e-60	206
rs:WP_014015941	5,10-methylene-tetrahydrofolate dehydrogenase [Megasphaera elsdenii].	39.86	291	160	4	4	292	2	279	1e-60	206
rs:WP_006945588	5,10-methylene-tetrahydrofolate dehydrogenase [Dermacoccus sp. Ellin185].	39.86	286	159	5	1	286	1	273	1e-60	206
tr:W1U1Y0_CLOBU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.79	289	163	2	3	291	10	287	1e-60	206
rs:XP_012269658	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Athalia rosae].	41.44	292	163	4	5	292	24	311	1e-60	218
rs:XP_011560163	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like, partial [Plutella xylostella].	42.80	264	144	3	33	293	43	302	1e-60	209
rs:XP_002669572	predicted protein [Naegleria gruberi].	39.26	298	161	7	5	285	12	306	1e-60	207
rs:WP_036459640	methenyltetrahydrofolate cyclohydrolase [Mycobacterium intracellulare].	40.55	291	162	4	1	291	1	280	1e-60	206
rs:WP_034843831	methenyltetrahydrofolate cyclohydrolase [Inquilinus limosus].	38.33	287	170	3	6	292	6	285	1e-60	206
rs:XP_005961635	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Pantholops hodgsonii].	40.54	296	167	4	3	293	4	295	1e-60	217
rs:WP_007773352	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium colombiense].	39.73	292	165	4	1	292	1	281	1e-60	206
rs:XP_012269657	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Athalia rosae].	41.44	292	163	4	5	292	27	314	1e-60	217
rs:WP_043316637	5,10-methylene-tetrahydrofolate cyclohydrolase [Microbulbifer sp. HZ11].	37.76	294	168	3	1	293	1	280	1e-60	206
tr:S4MSG7_9ACTO	SubName: Full=Putative Bifunctional protein FolD 2 {ECO:0000313|EMBL:EPJ38505.1};	41.48	270	148	4	1	270	1	260	1e-60	211
rs:WP_036551405	methenyltetrahydrofolate cyclohydrolase [Nocardioides sp. UNC345MFTsu5.1].	39.04	292	167	4	1	292	1	281	1e-60	206
rs:XP_004649313	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Jaculus jaculus].	41.55	296	164	4	3	293	4	295	1e-60	217
rs:WP_015105138	bifunctional protein FolD [Saccharothrix espanaensis].	41.30	293	161	5	1	293	4	285	1e-60	206
rs:WP_035440722	methenyltetrahydrofolate cyclohydrolase, partial [Asaia sp. SF2.1].	44.07	270	145	2	22	291	1	264	1e-60	205
rs:WP_006731830	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus iners].	41.26	286	156	4	5	290	4	277	1e-60	206
rs:WP_006733890	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus iners].	41.61	286	155	4	5	290	4	277	1e-60	206
tr:A0A0A1WU59_BACCU	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:JAD02171.1}; Flags: Fragment;	45.16	279	145	4	15	289	25	299	1e-60	217
rs:WP_015776152	5,10-methylene-tetrahydrofolate dehydrogenase [Brachybacterium faecium].	41.55	296	165	5	1	292	1	292	1e-60	206
rs:WP_006329426	bifunctional protein FolD [Mesorhizobium sp. STM 4661].	40.21	291	165	4	6	294	10	293	1e-60	206
gpu:AP014573_3728	bifunctional methylenetetrahydrofolatedehydrogenase/ methenyltetrahydrofolate cyclohydrolase [Mycobacterium tuberculosis str. Kurono]	40.21	291	163	4	1	291	25	304	1e-60	206
rs:WP_033812207	methenyltetrahydrofolate cyclohydrolase, partial [Escherichia coli].	52.40	208	89	3	90	297	1	198	1e-60	203
rs:WP_040997770	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. SOD10].	40.77	287	163	3	6	292	10	289	1e-60	206
rs:WP_010145534	5,10-methylene-tetrahydrofolate dehydrogenase [Citricoccus sp. CH26A].	40.41	292	160	6	1	286	1	284	1e-60	206
rs:WP_033127659	methenyltetrahydrofolate cyclohydrolase [Clostridium butyricum].	40.21	286	160	2	6	291	1	275	1e-60	205
rs:XP_011382778	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Pteropus vampyrus].	40.54	296	167	4	3	293	4	295	1e-60	217
rs:WP_024023445	5,10-methylene-tetrahydrofolate dehydrogenase [Marinomonas profundimaris].	36.77	291	170	2	1	291	1	277	1e-60	205
sp:FOLD_JANSC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	43.10	290	161	1	3	292	12	297	2e-60	206
rs:XP_008635556	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Corvus brachyrhynchos].	42.71	295	158	5	5	293	11	300	2e-60	217
rs:XP_008699196	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Ursus maritimus].	40.67	300	165	5	3	293	4	299	2e-60	217
tr:A0A0D0AZB5_9HOMO	SubName: Full=Unplaced genomic scaffold CY34scaffold_20, whole genome shotgun sequence {ECO:0000313|EMBL:KIK47046.1};	42.71	295	158	5	1	289	1	290	2e-60	217
rs:WP_027964746	5,10-methylene-tetrahydrofolate cyclohydrolase [Halalkalibacillus halophilus].	37.72	289	165	3	5	293	6	279	2e-60	206
sp:FOLD_ARTS2	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.27	298	165	6	2	293	4	294	2e-60	206
rs:WP_006734183	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus iners].	41.61	286	155	4	5	290	4	277	2e-60	205
rs:WP_035933170	methenyltetrahydrofolate cyclohydrolase [Knoellia aerolata].	39.52	291	168	5	1	291	1	283	2e-60	206
rs:WP_020077010	5,10-methylene-tetrahydrofolate dehydrogenase [Cryocola sp. 340MFSha3.1].	41.28	298	166	6	1	294	1	293	2e-60	206
tr:A0A0D0DNF1_9HOMO	SubName: Full=Unplaced genomic scaffold scaffold_12, whole genome shotgun sequence {ECO:0000313|EMBL:KIL00398.1};	42.18	294	160	4	2	289	5	294	2e-60	217
tr:W8YQL4_9BACL	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:CDN42146.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CDN42146.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CDN42146.1}; Flags: Fragment;	39.24	288	160	3	5	292	10	282	2e-60	206
rs:WP_035007010	methenyltetrahydrofolate cyclohydrolase [Corynebacterium jeikeium].	43.39	295	149	6	1	291	1	281	2e-60	205
rs:WP_020857054	bifunctional protein FolD [SAR86 cluster bacterium SAR86A].	39.59	293	162	4	1	293	1	278	2e-60	205
tr:A0A0A1MXU5_9FUNG	SubName: Full=Putative C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:CEI91857.1};	44.63	242	127	3	1	239	1	238	2e-60	204
rs:WP_012871786	methenyltetrahydrofolate cyclohydrolase [Sphaerobacter thermophilus].	38.89	288	164	3	6	293	5	280	2e-60	205
rs:WP_031938631	methenyltetrahydrofolate cyclohydrolase [Rhodococcus defluvii].	39.86	291	164	4	1	291	4	283	2e-60	206
rs:WP_044519265	methenyltetrahydrofolate cyclohydrolase [Mycobacterium septicum].	41.52	289	152	5	1	286	1	275	2e-60	205
rs:WP_038372813	methenyltetrahydrofolate cyclohydrolase [Brachybacterium phenoliresistens].	40.07	297	168	7	1	292	1	292	2e-60	206
rs:WP_023272400	FolD protein [Acinetobacter nectaris].	39.18	291	166	3	3	293	2	281	2e-60	205
rs:WP_017197818	5,10-methylene-tetrahydrofolate dehydrogenase [Arthrobacter sp. M2012083].	39.06	297	167	5	2	292	5	293	2e-60	206
rs:WP_023809024	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. L2C084A000].	39.86	291	166	4	6	294	10	293	2e-60	206
tr:D9V3W7_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.85	284	157	4	1	284	4	276	2e-60	205
rs:WP_027501736	methenyltetrahydrofolate cyclohydrolase [Rhodococcus sp. UNC363MFTsu5.1].	42.27	291	157	4	1	291	4	283	2e-60	205
rs:WP_034992888	methenyltetrahydrofolate cyclohydrolase [Corynebacterium jeikeium].	43.39	295	149	6	1	291	1	281	2e-60	205
rs:WP_032118916	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. CL-2].	39.79	289	163	2	3	291	2	279	2e-60	205
rs:WP_034972408	methenyltetrahydrofolate cyclohydrolase [Corynebacterium jeikeium].	43.39	295	149	7	1	291	1	281	2e-60	205
rs:WP_047264381	methenyltetrahydrofolate cyclohydrolase [Candidatus Liberibacter africanus].	42.81	292	158	5	3	291	2	287	2e-60	206
tr:R5QQ46_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	50.00	216	98	3	73	288	11	216	2e-60	203
rs:WP_043607505	methenyltetrahydrofolate cyclohydrolase [Cellulomonas carbonis].	41.22	296	161	6	3	292	7	295	2e-60	206
rs:WP_030470821	methenyltetrahydrofolate cyclohydrolase [Lechevalieria aerocolonigenes].	41.69	295	152	7	1	292	1	278	2e-60	205
rs:WP_017595014	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis potens].	43.01	286	152	5	1	286	1	275	2e-60	205
rs:WP_028187022	5,10-methylene-tetrahydrofolate cyclohydrolase [Salinispora arenicola].	37.46	291	168	2	1	291	1	277	2e-60	205
tr:K9GJZ3_PEND1	SubName: Full=C1 tetrahydrofolate synthase, putative {ECO:0000313|EMBL:EKV21209.1};	41.98	293	163	3	1	290	1	289	2e-60	217
rs:WP_003782021	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces naeslundii].	38.93	298	169	6	2	293	8	298	2e-60	206
rs:WP_036445663	methenyltetrahydrofolate cyclohydrolase [Mycobacterium vulneris].	41.87	289	151	5	1	286	1	275	2e-60	205
rs:XP_003797449	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Otolemur garnettii].	39.86	296	169	4	3	293	4	295	2e-60	217
rs:WP_014742767	5,10-methylene-tetrahydrofolate dehydrogenase [Modestobacter marinus].	42.96	284	151	4	1	284	1	273	2e-60	205
rs:WP_041817719	methenyltetrahydrofolate cyclohydrolase [Lactobacillus sanfranciscensis].	39.30	285	160	4	4	286	3	276	2e-60	205
tr:A0A0D6L462_9BILA	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EPB65679.1};	48.71	232	106	2	72	290	353	584	2e-60	213
rs:WP_029022350	5,10-methylene-tetrahydrofolate cyclohydrolase [Salinispora arenicola].	37.80	291	167	2	1	291	1	277	2e-60	205
rs:WP_018134819	5,10-methylene-tetrahydrofolate dehydrogenase [Acaricomes phytoseiuli].	40.13	299	166	6	1	293	1	292	2e-60	205
rs:WP_038677417	methenyltetrahydrofolate cyclohydrolase [Pimelobacter simplex].	39.04	292	167	4	1	292	1	281	2e-60	205
rs:WP_033718433	methenyltetrahydrofolate cyclohydrolase [Mycobacterium avium].	40.21	291	163	4	1	291	1	280	2e-60	205
rs:WP_034977836	methenyltetrahydrofolate cyclohydrolase [Corynebacterium jeikeium].	42.61	291	157	5	1	291	4	284	2e-60	205
rs:XP_007347764	FTHFS-domain-containing protein [Auricularia delicata TFB-10046 SS5].	41.55	296	163	4	2	291	25	316	2e-60	217
tr:H2Z0I1_CIOSA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAVP00000011093}; Flags: Fragment;	44.07	295	155	4	3	291	3	293	2e-60	216
rs:XP_004738971	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Mustela putorius furo].	40.54	296	167	4	3	293	4	295	2e-60	216
rs:WP_005307926	FolD protein [Acinetobacter sp. NIPH 542].	38.36	292	167	4	3	293	2	281	3e-60	205
rs:XP_641355	methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase [Dictyostelium discoideum AX4].	38.57	293	170	4	6	289	86	377	3e-60	209
rs:WP_044097367	methenyltetrahydrofolate cyclohydrolase [Mycobacterium canettii].	40.21	291	163	4	1	291	1	280	3e-60	205
rs:XP_011589854	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Aquila chrysaetos canadensis].	41.75	297	162	5	3	293	4	295	3e-60	216
tr:G2KWA4_LACSM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.30	285	160	4	4	286	8	281	3e-60	205
rs:WP_032381123	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	39.72	287	162	4	6	292	7	282	3e-60	205
rs:XP_571769	folic acid and derivative metabolism-related protein [Cryptococcus neoformans var. neoformans JEC21].	39.67	305	164	6	2	291	74	373	3e-60	217
sp:FOLD_MYCPA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.55	291	162	4	1	291	1	280	3e-60	205
tr:A0A060T8K2_BLAAD	SubName: Full=ARAD1C37708p {ECO:0000313|EMBL:CDP35531.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CDP35531.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CDP35531.1}; EC=6.3.4.3 {ECO:0000313|EMBL:CDP35531.1};	40.41	292	167	3	3	291	2	289	3e-60	216
rs:WP_037714107	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces mirabilis].	38.36	292	166	2	1	292	2	279	3e-60	205
rs:WP_026551523	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. H20].	39.86	296	165	6	2	291	4	292	3e-60	205
rs:XP_004371001	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Trichechus manatus latirostris].	40.20	296	168	4	3	293	4	295	3e-60	216
rs:WP_006845762	5,10-methylene-tetrahydrofolate dehydrogenase [Weissella koreensis].	39.93	288	158	6	3	286	2	278	3e-60	205
sp:FOLD_MYCFO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	42.11	285	148	5	5	286	8	278	3e-60	205
rs:WP_024924648	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Mesorhizobium].	39.72	287	166	3	6	292	9	288	3e-60	206
rs:WP_003919206	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium xenopi].	40.41	292	163	4	1	292	1	281	3e-60	205
rs:WP_015303842	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium canettii].	40.21	291	163	4	1	291	1	280	3e-60	204
rs:WP_005008308	FolD 2 [Acinetobacter bouvetii].	38.70	292	166	4	3	293	2	281	3e-60	205
rs:XP_774119	hypothetical protein CNBG4190 [Cryptococcus neoformans var. neoformans B-3501A].	39.67	305	164	6	2	291	74	373	3e-60	217
rs:WP_043479399	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. SPG23].	40.60	298	164	6	2	293	4	294	3e-60	205
rs:WP_020253514	MULTISPECIES: hypothetical protein [unclassified Cloacimonetes].	38.11	286	175	2	4	289	3	286	3e-60	205
rs:WP_022510061	bifunctional protein FolD [Clostridium sp. CAG:609].	39.65	285	151	4	5	286	2	268	3e-60	204
tr:F1R9G9_DANRE	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSDARP00000017895}; Flags: Fragment;	42.76	297	157	6	3	291	4	295	3e-60	216
rs:WP_028642683	methenyltetrahydrofolate cyclohydrolase [Nocardioides sp. URHA0020].	39.93	293	163	5	1	293	1	280	3e-60	204
tr:M5E5I7_MALS4	SubName: Full=Genomic scaffold, msy_sf_2 {ECO:0000313|EMBL:CCU97675.1};	43.34	293	155	5	6	291	11	299	3e-60	216
rs:XP_005686027	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Capra hircus].	40.54	296	167	4	3	293	4	295	3e-60	216
rs:WP_046842497	methenyltetrahydrofolate cyclohydrolase ['Deinococcus soli' Cha et al. 2014].	46.12	258	132	3	35	292	34	284	3e-60	205
rs:WP_018171772	5,10-methylene-tetrahydrofolate dehydrogenase [Microbacterium sp. 292MF].	40.48	294	166	6	1	290	1	289	3e-60	205
rs:WP_022448144	bifunctional protein FolD [Firmicutes bacterium CAG:460].	39.01	282	157	3	5	286	2	268	3e-60	204
rs:XP_005506427	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Columba livia].	41.55	296	164	4	3	293	4	295	3e-60	216
gp:AY487229_6	FolD [Mycobacterium fortuitum subsp. fortuitum DSM 46621]	42.11	285	148	5	5	286	17	287	3e-60	205
rs:WP_024356574	methenyltetrahydrofolate cyclohydrolase [Leucobacter chironomi].	40.07	297	169	5	1	293	1	292	3e-60	205
rs:WP_024820049	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. 31Y].	39.06	297	167	5	2	292	5	293	3e-60	205
rs:WP_034232867	methenyltetrahydrofolate cyclohydrolase, partial [Arcanobacterium sp. S3PF19].	41.36	295	164	5	1	291	1	290	3e-60	205
rs:WP_016572286	methylenetetrahydrofolate dehydrogenase [Streptomyces albulus].	40.00	290	160	2	2	291	8	283	3e-60	205
tr:A0A0D3B8Q0_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo3g052170.1};	42.71	288	140	4	6	291	60	324	3e-60	206
rs:XP_007184341	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Balaenoptera acutorostrata scammoni].	40.88	296	166	4	3	293	4	295	4e-60	216
rs:WP_026844786	methenyltetrahydrofolate cyclohydrolase [Geodermatophilaceae bacterium URHA0031].	41.10	292	161	4	1	292	1	281	4e-60	205
rs:WP_016678902	methenyltetrahydrofolate cyclohydrolase, partial [Yersinia pestis].	50.23	215	103	1	1	215	1	211	4e-60	202
rs:WP_030900223	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5126].	36.90	290	169	2	2	291	12	287	4e-60	205
rs:XP_012544431	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Bombyx mori].	42.37	295	162	4	3	293	2	292	4e-60	216
rs:WP_027027684	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. URHA0056].	39.73	292	165	5	6	294	10	293	4e-60	205
rs:XP_011971142	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Ovis aries musimon].	40.54	296	167	4	3	293	4	295	4e-60	216
rs:WP_005519891	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium matruchotii].	43.43	297	149	6	1	293	4	285	4e-60	204
rs:XP_003756399	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Sarcophilus harrisii].	43.97	282	147	5	15	290	28	304	4e-60	216
rs:WP_003677290	tetrahydrofolate dehydrogenase [Lactobacillus coryniformis].	42.31	286	154	3	5	290	3	277	4e-60	204
rs:WP_047118391	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. YC-RL1].	39.53	296	162	7	1	292	3	285	4e-60	204
rs:WP_015103328	bifunctional protein FolD [Saccharothrix espanaensis].	39.31	290	162	2	1	290	1	276	4e-60	204
rs:WP_028266351	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. MA-N2].	38.78	294	170	6	2	291	6	293	4e-60	205
rs:WP_001229853	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter baumannii].	38.36	292	167	4	3	293	2	281	4e-60	204
rs:WP_005140230	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium rhodesiae].	40.34	295	159	5	1	292	1	281	4e-60	204
rs:WP_026419434	methenyltetrahydrofolate cyclohydrolase [Actinoalloteichus cyanogriseus].	41.90	284	154	4	1	284	1	273	4e-60	204
rs:WP_030605275	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces fulvoviolaceus].	38.49	291	165	2	3	293	4	280	4e-60	204
rs:WP_028647369	methenyltetrahydrofolate cyclohydrolase [Nocardiopsis sp. CNT312].	41.58	291	159	4	1	291	1	280	4e-60	204
rs:XP_006072213	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Bubalus bubalis].	40.54	296	167	4	3	293	4	295	4e-60	216
tr:A0A0C7DGK7_MYCBI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.21	291	163	4	1	291	25	304	4e-60	205
rs:WP_046425551	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. MUSC136T].	38.28	290	165	2	3	292	4	279	4e-60	204
rs:WP_040509441	5,10-methylene-tetrahydrofolate cyclohydrolase [Gordonia soli].	36.81	288	168	2	6	293	1	274	4e-60	204
rs:XP_010887854	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Esox lucius].	42.52	294	160	4	2	290	23	312	4e-60	215
rs:XP_004426292	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Ceratotherium simum simum].	40.20	296	168	4	3	293	4	295	4e-60	216
rs:WP_037174695	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	39.72	287	162	4	6	292	7	282	4e-60	204
rs:XP_010586987	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Loxodonta africana].	41.67	288	159	4	11	293	19	302	4e-60	216
sp:FOLD_CLOBB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.75	289	166	2	3	291	2	279	4e-60	204
tr:F9WQ73_TRYVY	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic, putative {ECO:0000313|EMBL:CCD19700.1};	39.32	295	170	4	3	292	13	303	4e-60	205
rs:WP_006382469	tetrahydrofolate dehydrogenase [Streptomyces turgidiscabies].	39.86	291	160	3	1	291	1	276	4e-60	204
tr:A0A0A0BQN5_9CELL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.22	296	161	6	3	292	41	329	4e-60	206
rs:XP_009562677	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Cuculus canorus].	42.09	297	161	5	3	293	4	295	5e-60	216
rs:WP_013878022	methenyltetrahydrofolate cyclohydrolase [Buchnera aphidicola].	42.12	292	160	2	1	292	1	283	5e-60	204
rs:WP_003371736	tetrahydrofolate dehydrogenase [Clostridium botulinum].	38.41	289	167	2	3	291	2	279	5e-60	204
tr:G3W5I2_SARHA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSHAP00000010687}; Flags: Fragment;	43.97	282	147	5	15	290	17	293	5e-60	216
rs:WP_006737906	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus iners].	41.26	286	156	4	5	290	4	277	5e-60	204
rs:WP_035786428	methenyltetrahydrofolate cyclohydrolase [Clostridium botulinum].	38.41	289	167	2	3	291	2	279	5e-60	204
rs:WP_030800136	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-337].	38.70	292	165	2	2	293	4	281	5e-60	204
rs:WP_026426822	methenyltetrahydrofolate cyclohydrolase [Actinomyces slackii].	40.07	297	165	6	2	292	8	297	5e-60	205
rs:WP_043528923	methenyltetrahydrofolate cyclohydrolase [Actinoplanes utahensis].	39.52	291	167	3	2	292	3	284	5e-60	204
rs:WP_014921068	5,10-methylene-tetrahydrofolate dehydrogenase [Arthrobacter sp. Rue61a].	39.06	297	167	5	2	292	5	293	5e-60	204
rs:WP_041320128	methenyltetrahydrofolate cyclohydrolase [Mycobacterium sp. JDM601].	40.83	289	154	6	1	286	1	275	5e-60	204
tr:A0A0A0J9F5_9MICO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.73	292	167	5	1	292	4	286	5e-60	204
rs:WP_017934643	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardioides sp. Iso805N].	40.41	292	163	4	1	292	1	281	5e-60	204
rs:WP_003650084	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter].	38.36	292	167	4	3	293	2	281	5e-60	204
rs:WP_046182889	methenyltetrahydrofolate cyclohydrolase [Mycobacterium nebraskense].	39.73	292	165	5	1	292	1	281	5e-60	204
tr:F9F7U9_FUSOF	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGU87080.1};	41.52	289	155	4	1	286	1	278	5e-60	216
rs:WP_030411060	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-1448].	38.70	292	165	2	2	293	4	281	5e-60	204
rs:WP_045549337	methenyltetrahydrofolate cyclohydrolase [Nocardioides luteus].	38.57	293	167	5	1	293	1	280	5e-60	204
rs:WP_017837186	5,10-methylene-tetrahydrofolate dehydrogenase [Dietzia sp. UCD-THP].	41.38	290	151	6	1	286	1	275	5e-60	204
tr:Q2UQ35_ASPOR	SubName: Full=C1-tetrahydrofolate synthase {ECO:0000313|EMBL:BAE56330.1};	42.47	292	156	3	1	290	1	282	5e-60	216
rs:WP_026531093	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sanguinis].	40.13	299	164	7	1	292	1	291	5e-60	204
sp:FOLD_LACAC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	45.04	282	141	5	3	283	2	270	5e-60	204
tr:A0A0A1FZV7_9MYCO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.11	285	148	5	5	286	1	271	5e-60	204
tr:G3TKZ3_LOXAF	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLAFP00000015525}; Flags: Fragment;	41.16	294	164	4	5	293	5	294	5e-60	216
rs:WP_012950395	5,10-methylene-tetrahydrofolate dehydrogenase [Geodermatophilus obscurus].	42.16	287	155	4	1	287	1	276	6e-60	204
rs:WP_045920294	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium angulatum].	39.73	292	167	5	6	293	5	291	6e-60	204
rs:WP_012918944	5,10-methylene-tetrahydrofolate dehydrogenase [Kribbella flavida].	40.49	284	159	4	1	284	1	274	6e-60	205
tr:A0A066WPE3_9BASI	SubName: Full=FTHFS-domain-containing protein {ECO:0000313|EMBL:KDN52839.1};	41.47	299	164	5	2	293	9	303	6e-60	216
tr:A0A087NHW2_9SPHN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	45.88	255	131	3	38	292	1	248	6e-60	203
rs:XP_007531794	PREDICTED: LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic [Erinaceus europaeus].	41.22	296	165	4	3	293	56	347	6e-60	216
gp:AM286690_1208	5, 10-methylenetetrahydromethanopterin cyclohydrolase [Alcanivorax borkumensis SK2]	37.76	294	168	3	1	293	55	334	6e-60	206
rs:WP_021601587	tetrahydrofolate dehydrogenase [Actinobaculum sp. oral taxon 183].	40.60	298	163	6	1	292	1	290	6e-60	204
rs:WP_005246946	FolD 2 [Acinetobacter sp. CIP 51.11].	38.70	292	166	4	3	293	2	281	6e-60	204
rs:WP_032393314	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	40.07	292	164	4	1	292	1	281	6e-60	204
tr:A0A0B5HHR1_9ARCH	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.59	287	165	3	4	290	2	271	6e-60	204
rs:WP_024458371	methenyltetrahydrofolate cyclohydrolase, partial [Mycobacterium bovis].	41.13	282	155	4	1	282	1	271	6e-60	204
rs:WP_023692345	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. LSJC268A00].	40.21	286	164	3	6	291	10	288	6e-60	205
rs:WP_010613135	methenyltetrahydrofolate cyclohydrolase, partial [Actinomyces oris].	41.22	279	151	6	21	293	1	272	6e-60	204
rs:WP_034162179	methenyltetrahydrofolate cyclohydrolase [Mycobacterium tuberculosis].	40.21	291	163	4	1	291	1	280	6e-60	204
rs:WP_006204026	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium amorphae].	40.28	288	163	4	6	292	10	289	6e-60	204
rs:XP_007814080	C-1-tetrahydrofolate synthase [Metarhizium acridum CQMa 102].	40.89	291	158	4	1	288	132	411	6e-60	216
tr:H6R2V1_NOCCG	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.11	287	158	3	6	292	6	281	6e-60	204
rs:WP_009501303	MULTISPECIES: tetrahydrofolate dehydrogenase [Acinetobacter calcoaceticus/baumannii complex].	38.36	292	167	4	3	293	2	281	7e-60	204
rs:XP_002846160	formate-tetrahydrofolate ligase [Arthroderma otae CBS 113480].	41.30	293	165	3	1	290	1	289	7e-60	215
rs:XP_007628809	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X4 [Cricetulus griseus].	44.49	263	139	3	3	259	113	374	7e-60	207
tr:M4BAS2_HYAAE	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:HpaP803382};	41.00	300	157	4	3	290	2	293	7e-60	204
rs:WP_045730148	methenyltetrahydrofolate cyclohydrolase [Arthrobacter chlorophenolicus].	40.27	298	165	6	2	293	6	296	7e-60	204
rs:WP_020768509	tetrahydrofolate dehydrogenase [Leptospira sp. B5-022].	38.98	295	166	2	1	295	1	281	7e-60	204
rs:WP_037652560	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces griseofuscus].	38.73	284	160	2	3	286	4	273	7e-60	204
rs:WP_007232163	5,10-methylene-tetrahydrofolate dehydrogenase [gamma proteobacterium HTCC2207].	40.00	295	160	5	1	293	1	280	7e-60	204
tr:T5ADL3_OPHSC	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:EQL00506.1};	41.55	296	159	4	1	293	244	528	7e-60	217
tr:X5LQT6_9MYCO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.11	285	148	5	5	286	8	278	7e-60	204
rs:WP_001229854	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter baumannii].	38.36	292	167	4	3	293	2	281	7e-60	204
rs:WP_040157399	methenyltetrahydrofolate cyclohydrolase [Mobilicoccus sp. SIT2].	39.73	292	163	5	1	292	1	279	7e-60	204
rs:WP_016140185	MULTISPECIES: FolD protein [Acinetobacter].	38.36	292	167	4	3	293	2	281	7e-60	204
rs:WP_013196999	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter oleivorans].	38.01	292	168	4	3	293	2	281	7e-60	204
rs:WP_004646309	MULTISPECIES: FolD 2 [Acinetobacter].	38.70	292	166	4	3	293	2	281	7e-60	204
rs:WP_009392206	tetrahydrofolate dehydrogenase [Acinetobacter sp. WC-141].	38.36	292	167	4	3	293	2	281	7e-60	204
rs:WP_006075878	5,10-methylene-tetrahydrofolate dehydrogenase [Halococcus saccharolyticus].	38.62	290	176	2	2	291	3	290	7e-60	204
rs:WP_028635664	methenyltetrahydrofolate cyclohydrolase [Nocardioides sp. URHA0032].	38.91	293	166	5	1	293	1	280	7e-60	204
rs:WP_028044965	methenyltetrahydrofolate cyclohydrolase [Cellulomonas sp. URHE0023].	40.34	295	167	6	1	291	1	290	7e-60	204
rs:WP_040106433	hypothetical protein [Salinicoccus roseus].	40.27	293	163	5	5	296	4	285	7e-60	204
tr:M1E5G3_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.87	289	155	4	1	289	1	276	7e-60	204
rs:XP_003006337	C-1-tetrahydrofolate synthase [Verticillium alfalfae VaMs.102].	45.93	246	127	2	50	293	33	274	7e-60	215
rs:WP_044372768	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces ahygroscopicus].	39.66	290	161	2	2	291	8	283	7e-60	204
rs:WP_045271954	methenyltetrahydrofolate cyclohydrolase [Microbacterium azadirachtae].	41.89	296	163	6	1	292	1	291	7e-60	204
rs:WP_005174072	bifunctional protein FolD [Gordonia aichiensis].	40.27	293	164	4	1	293	1	282	7e-60	204
tr:H0HXY6_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.72	287	166	3	6	292	9	288	8e-60	204
tr:A0A051UI63_MYCTX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.07	292	164	4	1	292	43	323	8e-60	205
rs:WP_031964130	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	38.36	292	167	4	3	293	2	281	8e-60	204
rs:WP_014694044	5,10-methylene-tetrahydrofolate dehydrogenase [Actinoplanes sp. SE50/110].	37.80	291	172	3	2	292	7	288	8e-60	204
tr:M7A9U6_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.27	293	164	4	1	293	1	282	8e-60	204
rs:WP_040587676	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium alhagi].	39.72	287	166	3	6	292	11	290	8e-60	204
rs:WP_027164320	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. WSM3224].	40.42	287	164	3	6	292	10	289	8e-60	204
rs:WP_008859412	5,10-methylene-tetrahydrofolate dehydrogenase [Dialister succinatiphilus].	40.69	290	160	3	3	292	2	279	8e-60	204
rs:WP_003064295	methylenetetrahydrofolate dehydrogenase [Amycolatopsis vancoresmycina].	39.93	293	165	4	1	293	1	282	8e-60	204
tr:G6D0B7_DANPL	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:EHJ73062.1};	46.39	263	134	3	34	293	36	294	8e-60	215
rs:WP_038517690	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces albulus].	39.66	290	161	2	2	291	8	283	8e-60	204
rs:WP_023804489	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Mesorhizobium].	40.21	286	164	3	6	291	10	288	8e-60	204
tr:W5QJ31_SHEEP	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOARP00000022733}; Flags: Fragment;	40.54	296	167	4	3	293	22	313	8e-60	215
rs:WP_028126879	methenyltetrahydrofolate cyclohydrolase [Entomoplasma lucivorax].	43.26	282	151	2	4	285	2	274	8e-60	204
rs:WP_001229847	bifunctional protein FolD [Acinetobacter baumannii].	38.36	292	167	4	3	293	2	281	8e-60	204
rs:WP_036390039	methenyltetrahydrofolate cyclohydrolase [Mycobacterium farcinogenes].	41.87	289	151	5	1	286	1	275	9e-60	204
rs:WP_045928270	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus kullabergensis].	38.28	290	167	3	3	292	2	279	9e-60	203
rs:WP_023830448	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. L103C119B0].	40.21	286	164	3	6	291	10	288	9e-60	204
tr:F7JIR4_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	46.72	259	127	4	5	263	4	251	9e-60	204
rs:XP_004010764	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Ovis aries].	40.54	296	167	4	3	293	4	295	9e-60	215
rs:XP_010170291	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Caprimulgus carolinensis].	41.14	299	165	5	1	293	1	294	9e-60	215
tr:A0A0B0KVX8_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.36	292	167	4	3	293	2	281	9e-60	203
rs:WP_043416667	methenyltetrahydrofolate cyclohydrolase [Corynebacterium variabile].	41.55	284	153	5	1	284	1	271	9e-60	204
rs:WP_037816426	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Actinomycetales].	40.85	284	157	4	1	284	1	273	9e-60	204
rs:WP_032384760	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	39.72	287	162	4	6	292	7	282	9e-60	204
rs:XP_011550484	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Plutella xylostella].	40.74	297	168	4	1	293	1	293	9e-60	215
rs:WP_017597066	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis lucentensis].	41.44	292	160	5	1	292	1	281	9e-60	203
rs:WP_019836754	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter sp. MDS7A].	38.36	292	167	4	3	293	2	281	9e-60	203
rs:WP_004736915	FolD protein [Acinetobacter baumannii].	38.36	292	167	4	3	293	2	281	9e-60	203
sp:FOLD_ACIBT	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.36	292	167	4	3	293	2	281	9e-60	203
rs:XP_003648021	hypothetical protein Ecym_7378 [Eremothecium cymbalariae DBVPG#7215].	41.50	294	163	4	5	293	3	292	1e-59	215
rs:WP_001229852	bifunctional protein FolD [Acinetobacter baumannii].	38.36	292	167	4	3	293	2	281	1e-59	203
rs:WP_042898479	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter oleivorans].	38.36	292	167	4	3	293	2	281	1e-59	203
tr:A0A0A0JY60_9MICO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.18	291	169	5	1	291	4	286	1e-59	204
rs:XP_005967817	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2-like [Pantholops hodgsonii].	39.86	286	165	3	6	291	74	352	1e-59	206
rs:WP_024441990	methenyltetrahydrofolate cyclohydrolase [Mycobacterium sp. UM_WGJ].	40.91	286	158	5	1	286	1	275	1e-59	203
rs:WP_045429235	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter calcoaceticus].	38.36	292	167	4	3	293	2	281	1e-59	203
rs:WP_017480492	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter calcoaceticus].	38.36	292	167	4	3	293	2	281	1e-59	203
tr:V7P9V6_MYCAV	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:ETB55780.1}; EC=1.5.1.5 {ECO:0000313|EMBL:ETB55780.1}; EC=3.5.4.9 {ECO:0000313|EMBL:ETB55780.1}; Flags: Fragment;	40.21	291	163	4	1	291	30	309	1e-59	204
rs:WP_002115552	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter].	38.36	292	167	4	3	293	2	281	1e-59	203
rs:WP_026869319	methenyltetrahydrofolate cyclohydrolase [Inquilinus limosus].	37.98	287	171	3	6	292	6	285	1e-59	204
rs:WP_044440110	methenyltetrahydrofolate cyclohydrolase [Agreia bicolorata].	40.74	297	163	5	1	289	1	292	1e-59	204
rs:WP_013120571	methylenetetrahydrofolate dehydrogenase [Thermincola potens].	39.93	293	161	5	1	290	1	281	1e-59	203
rs:WP_036502029	methenyltetrahydrofolate cyclohydrolase, partial [Nitrosococcus oceani].	50.93	214	95	3	78	291	3	206	1e-59	201
rs:WP_016137266	FolD protein [Acinetobacter calcoaceticus].	37.46	291	171	2	3	293	2	281	1e-59	203
sp:FOLD_CLAM3	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.32	295	170	6	1	291	1	290	1e-59	204
rs:WP_038344668	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	38.36	292	167	4	3	293	2	281	1e-59	203
rs:WP_019159354	5,10-methylene-tetrahydrofolate dehydrogenase [Brevibacterium senegalense].	39.25	293	165	6	6	292	14	299	1e-59	204
rs:WP_013158833	5,10-methylene-tetrahydrofolate dehydrogenase [Meiothermus silvanus].	42.56	289	150	5	6	291	3	278	1e-59	203
rs:WP_028456971	5,10-methylene-tetrahydrofolate cyclohydrolase [Chloroflexus sp. Y-396-1].	39.93	293	166	2	1	293	1	283	1e-59	203
rs:WP_044435933	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter ursingii].	38.36	292	167	4	3	293	2	281	1e-59	203
rs:WP_005038726	FolD protein [Acinetobacter calcoaceticus].	38.36	292	167	4	3	293	2	281	1e-59	203
rs:WP_015936404	5,10-methylene-tetrahydrofolate dehydrogenase [Arthrobacter chlorophenolicus].	40.27	298	165	6	2	293	6	296	1e-59	204
rs:WP_018770230	5,10-methylene-tetrahydrofolate dehydrogenase [Arthrobacter sp. 162MFSha1.1].	40.83	289	158	6	2	284	6	287	1e-59	204
rs:WP_023670547	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Mesorhizobium].	40.77	287	161	4	6	291	10	288	1e-59	204
rs:WP_005524741	5,10-methylene-tetrahydrofolate dehydrogenase [Corynebacterium matruchotii].	43.43	297	149	6	1	293	4	285	1e-59	203
rs:WP_032037584	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	38.01	292	168	4	3	293	2	281	1e-59	203
rs:WP_005003423	FolD 2 [Acinetobacter ursingii].	38.36	292	167	4	3	293	2	281	1e-59	203
rs:WP_029252290	methenyltetrahydrofolate cyclohydrolase [Paraoerskovia marina].	42.76	290	157	5	1	286	1	285	1e-59	204
rs:WP_024437086	bifunctional protein FolD [Acinetobacter baumannii].	38.36	292	167	4	3	293	2	281	1e-59	203
rs:XP_004262167	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Orcinus orca].	40.20	296	168	4	3	293	4	295	1e-59	214
rs:WP_023788915	methylenetetrahydrofolate dehydrogenase [Spiroplasma apis].	40.85	284	155	3	1	284	1	271	1e-59	203
rs:WP_003826760	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium angulatum].	39.73	292	167	5	6	293	5	291	1e-59	203
rs:WP_041778426	methenyltetrahydrofolate cyclohydrolase [Beijerinckia indica].	39.80	299	165	5	2	290	8	301	1e-59	204
rs:XP_009648701	C-1-tetrahydrofolate synthase [Verticillium dahliae VdLs.17].	45.93	246	127	2	50	293	33	274	1e-59	214
rs:WP_041084603	bifunctional protein FolD [Clostridium botulinum].	38.06	289	168	2	3	291	2	279	1e-59	203
rs:WP_043124375	methenyltetrahydrofolate cyclohydrolase [Sinomonas sp. MUSC 117].	42.01	288	158	6	3	286	9	291	1e-59	204
rs:WP_042396761	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. JCC].	38.81	286	164	2	6	291	5	279	1e-59	203
rs:WP_029146038	methenyltetrahydrofolate cyclohydrolase [Microbacterium luticocti].	41.61	298	161	6	1	292	1	291	1e-59	203
rs:WP_010549866	5,10-methylene-tetrahydrofolate dehydrogenase [Brachybacterium paraconglomeratum].	41.22	296	166	5	1	292	1	292	1e-59	203
sp:FOLD_PELCD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.83	291	169	3	1	291	1	282	2e-59	203
rs:XP_006276264	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Alligator mississippiensis].	40.88	296	166	4	3	293	4	295	2e-59	214
sp:FOLD2_ARTAT	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.06	297	167	5	2	292	5	293	2e-59	203
rs:WP_033436806	methenyltetrahydrofolate cyclohydrolase [Saccharothrix sp. NRRL B-16314].	41.30	293	161	5	1	293	1	282	2e-59	203
rs:WP_025156708	methenyltetrahydrofolate cyclohydrolase [Leifsonia aquatica].	41.41	297	165	5	1	293	1	292	2e-59	203
rs:WP_013583773	5,10-methylene-tetrahydrofolate dehydrogenase [Microbacterium testaceum].	40.20	296	168	6	1	292	1	291	2e-59	203
rs:WP_033890372	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium saguini].	40.69	290	163	5	6	291	5	289	2e-59	203
rs:WP_013491950	5,10-methylene-tetrahydrofolate dehydrogenase [Intrasporangium calvum].	40.85	284	155	5	1	284	1	271	2e-59	203
rs:WP_028277329	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. I3].	39.53	296	167	6	2	292	12	300	2e-59	204
rs:WP_032033224	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	38.36	292	167	4	3	293	2	281	2e-59	203
rs:WP_009403834	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces sp. oral taxon 170].	38.59	298	170	6	2	293	8	298	2e-59	203
rs:WP_001229850	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter baumannii].	38.36	292	167	4	3	293	2	281	2e-59	202
rs:WP_031965069	bifunctional protein FolD [Acinetobacter baumannii].	38.01	292	168	4	3	293	2	281	2e-59	202
rs:WP_034272202	5,10-methylene-tetrahydrofolate cyclohydrolase [Actinospica robiniae].	38.70	292	165	2	2	293	6	283	2e-59	203
rs:WP_032405158	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	39.72	287	162	4	6	292	7	282	2e-59	203
sp:FOLD_CLAMS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.32	295	170	6	1	291	1	290	2e-59	203
tr:A0A0D2TC99_GOSRA	SubName: Full=Gossypium raimondii chromosome 11, whole genome shotgun sequence {ECO:0000313|EMBL:KJB73358.1};	45.83	240	124	2	2	239	70	305	2e-59	204
rs:XP_008347927	PREDICTED: bifunctional protein FolD 4, chloroplastic-like [Malus domestica].	46.25	240	123	2	2	239	71	306	2e-59	205
rs:WP_013718182	5,10-methylene-tetrahydrofolate dehydrogenase [Methanosaeta concilii].	44.79	288	143	4	5	290	7	280	2e-59	203
rs:WP_020662673	5,10-methylene-tetrahydrofolate dehydrogenase [Amycolatopsis benzoatilytica].	40.49	284	158	4	1	284	1	273	2e-59	202
rs:WP_030931189	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces violaceoruber].	37.46	291	168	2	3	293	4	280	2e-59	202
tr:R7UBL5_CAPTE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELU03765.1, ECO:0000313|EnsemblMetazoa:CapteP170278};	40.67	300	169	4	3	297	2	297	2e-59	214
rs:XP_312083	AGAP002830-PA [Anopheles gambiae str. PEST].	40.61	293	166	4	3	291	5	293	2e-59	214
rs:WP_041438305	hypothetical protein [Thermodesulfobium narugense].	41.52	289	156	4	1	289	4	279	2e-59	203
rs:WP_031217089	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. AK-YN10].	38.64	295	171	4	2	292	4	292	2e-59	203
rs:WP_021962454	bifunctional protein FolD [Mycoplasma sp. CAG:877].	43.26	282	146	3	4	285	2	269	2e-59	202
rs:XP_011154961	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Harpegnathos saltator].	42.12	292	161	4	5	292	9	296	2e-59	214
rs:WP_019067830	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. R1-NS-10].	38.49	291	165	2	3	293	4	280	2e-59	202
rs:WP_045125884	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter calcoaceticus].	38.36	292	167	4	3	293	2	281	2e-59	202
tr:A0A016SUZ0_9BILA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYB94518.1};	43.39	295	151	6	1	285	1	289	2e-59	203
rs:WP_031535937	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus sp. MB2021].	40.56	286	155	4	5	290	6	276	2e-59	202
rs:WP_010535157	5,10-methylene-tetrahydrofolate dehydrogenase [Brachybacterium squillarum].	42.71	288	157	5	1	284	1	284	2e-59	203
rs:WP_017816649	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter baumannii].	38.36	292	167	4	3	293	2	281	2e-59	202
rs:XP_011120727	hypothetical protein AOL_s00075g114 [Arthrobotrys oligospora ATCC 24927].	39.30	313	164	6	1	291	1	309	2e-59	214
rs:WP_014207454	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter calcoaceticus].	38.36	292	167	4	3	293	2	281	2e-59	202
rs:WP_018426621	methenyltetrahydrofolate cyclohydrolase [Hoeflea sp. 108].	39.72	287	166	3	6	292	10	289	2e-59	203
rs:WP_047323810	methenyltetrahydrofolate cyclohydrolase [Mycobacterium nebraskense].	39.04	292	167	5	1	292	1	281	2e-59	202
rs:WP_031460571	5,10-methylene-tetrahydrofolate cyclohydrolase [Chloroflexus sp. MS-G].	39.93	293	166	2	1	293	1	283	2e-59	202
rs:XP_004941143	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Gallus gallus].	41.61	298	125	3	3	294	46	300	2e-59	203
rs:XP_010090805	Bifunctional protein FolD [Morus notabilis].	40.55	291	134	2	3	293	11	262	2e-59	202
rs:WP_035488547	5,10-methylene-tetrahydrofolate cyclohydrolase [Gammaproteobacteria bacterium MOLA455].	38.78	294	165	3	1	293	1	280	2e-59	202
rs:WP_035848309	methenyltetrahydrofolate cyclohydrolase [Kitasatospora azatica].	41.10	292	161	5	1	292	1	281	2e-59	202
rs:WP_018777238	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Arthrobacter].	38.38	297	169	5	2	292	5	293	2e-59	203
rs:WP_045233419	methenyltetrahydrofolate cyclohydrolase [Deinococcus pimensis].	45.59	261	136	3	32	292	6	260	2e-59	202
tr:A0A0B4I0U3_9HYPO	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:KID85869.1};	40.89	291	158	4	1	288	175	454	2e-59	215
rs:WP_007554468	5,10-methylene-tetrahydrofolate dehydrogenase [Dialister micraerophilus].	39.47	266	149	3	5	270	2	255	2e-59	202
rs:XP_001994659	GH14901 [Drosophila grimshawi].	41.41	297	165	4	1	292	1	293	2e-59	214
rs:WP_004699641	FolD protein [Acinetobacter sp. NIPH 973].	38.36	292	167	4	3	293	2	281	2e-59	202
rs:WP_006295839	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium gallicum].	39.73	297	166	6	3	293	2	291	2e-59	202
rs:WP_017883698	5,10-methylene-tetrahydrofolate dehydrogenase [Leucobacter sp. UCD-THU].	39.86	296	169	5	1	292	1	291	2e-59	202
tr:L8X9E5_THACA	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:ELU45707.1};	40.60	298	145	5	3	290	115	390	2e-59	214
rs:WP_031995937	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	38.36	292	167	4	3	293	2	281	3e-59	202
rs:WP_045842641	methenyltetrahydrofolate cyclohydrolase [Mycobacterium lepromatosis].	40.56	286	159	5	1	286	1	275	3e-59	202
tr:A0A0E1PU78_ACIBA	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:BAN86681.1}; EC=1.5.1.5 {ECO:0000313|EMBL:BAN86681.1}; EC=3.5.4.9 {ECO:0000313|EMBL:BAN86681.1};	38.36	292	167	4	3	293	32	311	3e-59	203
tr:A0A066P799_ACIBA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.36	292	167	4	3	293	32	311	3e-59	203
rs:WP_039899079	methenyltetrahydrofolate cyclohydrolase, partial [Actinobaculum schaalii].	39.39	297	166	6	1	291	1	289	3e-59	202
tr:A0A024LYV6_9MYCO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.90	284	148	5	6	286	9	278	3e-59	202
rs:WP_038989938	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. W1].	39.19	296	163	7	1	292	1	283	3e-59	202
rs:WP_020031623	5,10-methylene-tetrahydrofolate dehydrogenase [gamma proteobacterium SCGC AAA300-D14].	39.46	294	163	4	1	293	1	280	3e-59	202
rs:XP_012665327	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Otolemur garnettii].	39.53	296	170	4	3	293	4	295	3e-59	213
rs:WP_044807747	methenyltetrahydrofolate cyclohydrolase, partial [Escherichia coli].	50.71	211	100	1	1	211	1	207	3e-59	200
tr:B2IH41_BEII9	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.80	299	165	5	2	290	22	315	3e-59	203
rs:WP_032744363	bifunctional protein FolD [Bifidobacterium longum].	40.34	290	164	5	6	291	5	289	3e-59	202
rs:WP_004939760	FolD 2 [Acinetobacter soli].	38.14	291	169	2	3	293	2	281	3e-59	202
tr:A0A016SW12_9BILA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYB94519.1};	43.39	295	151	6	1	285	31	319	3e-59	204
rs:WP_023735723	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. LNJC399B00].	40.62	288	162	4	6	292	10	289	3e-59	203
rs:WP_031973111	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	38.36	292	167	4	3	293	2	281	3e-59	202
rs:WP_026542876	methenyltetrahydrofolate cyclohydrolase [Arthrobacter nicotinovorans].	38.38	297	169	5	2	292	5	293	3e-59	202
rs:WP_012875015	methylenetetrahydrofolate dehydrogenase [Thermobaculum terrenum].	37.46	283	166	2	4	286	7	278	3e-59	202
sp:FOLD_CLOBA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.06	289	168	2	3	291	2	279	3e-59	202
rs:WP_006330424	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia rhizosphera].	39.93	293	165	5	1	293	7	288	3e-59	202
rs:WP_013188633	5,10-methylene-tetrahydrofolate dehydrogenase [Mobiluncus curtisii].	38.44	294	172	6	3	292	9	297	3e-59	202
tr:F5Z3W6_MYCSD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.48	289	155	6	1	286	4	278	3e-59	202
rs:WP_001229849	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter baumannii].	38.36	292	167	4	3	293	2	281	3e-59	202
tr:A0A0D0TRY8_CRYGA	SubName: Full=Unplaced genomic scaffold supercont1.3, whole genome shotgun sequence {ECO:0000313|EMBL:KIR49452.1};	39.34	305	165	6	2	291	74	373	3e-59	214
rs:WP_040990678	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium plurifarium].	40.07	287	165	3	6	292	10	289	3e-59	203
tr:A0A0D0UKX6_CRYGA	SubName: Full=Unplaced genomic scaffold supercont2.8, whole genome shotgun sequence {ECO:0000313|EMBL:KIR33520.1};	39.34	305	165	6	2	291	74	373	3e-59	214
tr:A0A0D0Z1Z8_CRYGA	SubName: Full=Unplaced genomic scaffold supercont2.2, whole genome shotgun sequence {ECO:0000313|EMBL:KIR88954.1};	39.34	305	165	6	2	291	74	373	3e-59	214
rs:WP_002133036	bifunctional protein FolD [Acinetobacter baumannii].	38.01	292	168	4	3	293	2	281	3e-59	202
tr:A0A0D0V2V3_CRYGA	SubName: Full=Unplaced genomic scaffold supercont1.4, whole genome shotgun sequence {ECO:0000313|EMBL:KIR41736.1};	39.34	305	165	6	2	291	74	373	3e-59	214
tr:G4TRI1_PIRID	SubName: Full=Probable MIS1-C1-tetrahydrofolate synthase, mitochondrial {ECO:0000313|EMBL:CCA73924.1};	40.13	299	166	6	2	291	72	366	3e-59	214
rs:WP_017261763	hypothetical protein [Lactobacillus rossiae].	41.33	300	161	6	1	297	1	288	3e-59	202
tr:A0A093Q7Y9_9PASS	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFW82550.1}; Flags: Fragment;	42.81	285	152	5	15	293	2	281	3e-59	213
rs:WP_017585341	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis ganjiahuensis].	40.07	292	164	4	1	292	1	281	3e-59	202
rs:WP_021875803	bifunctional protein FolD [Clostridium chauvoei].	38.28	290	168	2	3	292	2	280	3e-59	202
rs:XP_003195486	mitochondrial C1-tetrahydrofolate synthase; Mis1p [Cryptococcus gattii WM276].	39.34	305	165	6	2	291	74	373	3e-59	214
rs:WP_042640988	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. ORS3359].	40.42	287	164	3	6	292	10	289	3e-59	202
rs:WP_020381641	hypothetical protein, partial [Candidatus Poribacteria sp. WGA-4E].	43.02	258	136	3	29	286	9	255	3e-59	201
rs:WP_035550987	5,10-methylene-tetrahydrofolate cyclohydrolase [Burkholderia sp. 9120].	37.15	288	166	3	5	291	4	277	3e-59	202
rs:WP_016696837	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Actinoalloteichus].	42.25	284	153	5	1	284	1	273	3e-59	202
tr:G1LB67_AILME	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAMEP00000004140}; Flags: Fragment;	40.48	294	166	4	5	293	5	294	4e-59	213
rs:WP_030084727	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces decoyicus].	38.64	295	167	2	2	296	4	284	4e-59	202
sp:FOLD_BIFLS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.34	290	164	5	6	291	5	289	4e-59	202
tr:A0A0D0VAS8_CRYGA	SubName: Full=Unplaced genomic scaffold supercont1.3, whole genome shotgun sequence {ECO:0000313|EMBL:KIR67897.1};	39.34	305	165	6	2	291	74	373	4e-59	214
rs:WP_017826027	tetrahydrofolate dehydrogenase [Clostridium botulinum].	38.06	289	168	2	3	291	2	279	4e-59	202
rs:WP_030348412	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-1022].	39.04	292	162	4	3	293	4	280	4e-59	202
rs:WP_009409097	tetrahydrofolate dehydrogenase [Actinomyces sp. oral taxon 181].	39.25	293	169	6	3	291	9	296	4e-59	202
rs:WP_004972142	FolD 2 [Acinetobacter towneri].	38.70	292	166	4	3	293	2	281	4e-59	202
rs:WP_006897227	bifunctional protein FolD [Gordonia sihwensis].	40.54	296	159	6	1	293	1	282	4e-59	202
rs:WP_042760704	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	38.01	292	168	4	3	293	2	281	4e-59	202
rs:WP_017603441	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis alkaliphila].	41.02	295	163	5	1	295	1	284	4e-59	202
rs:WP_043505639	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces glaucescens].	38.14	291	166	2	3	293	4	280	4e-59	202
rs:WP_013770297	5,10-methylene-tetrahydrofolate dehydrogenase [Cellulomonas fimi].	40.00	295	168	6	1	291	1	290	4e-59	202
rs:WP_032007021	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	38.01	292	168	4	3	293	2	281	4e-59	202
rs:WP_043673435	methenyltetrahydrofolate cyclohydrolase [Clavibacter michiganensis].	39.32	295	170	6	1	291	1	290	4e-59	202
rs:XP_003683993	hypothetical protein TPHA_0A04840 [Tetrapisispora phaffii CBS 4417].	40.47	299	164	5	1	291	1	293	4e-59	213
rs:WP_046474774	5,10-methylene-tetrahydrofolate cyclohydrolase [marine gamma proteobacterium ASP10-03a].	38.44	294	166	3	1	293	1	280	4e-59	202
rs:WP_032683829	bifunctional protein FolD [Bifidobacterium longum].	40.00	290	165	5	6	291	5	289	4e-59	202
rs:WP_013777431	methenyltetrahydrofolate cyclohydrolase [Tepidanaerobacter acetatoxydans].	41.03	290	159	5	5	293	4	282	4e-59	202
rs:WP_045279373	methenyltetrahydrofolate cyclohydrolase [Microbacterium oxydans].	41.28	298	164	7	1	293	1	292	4e-59	202
rs:WP_044665735	methylenetetrahydrofolate dehydrogenase [Syntrophaceticus schinkii].	39.93	293	161	5	1	290	1	281	4e-59	202
rs:WP_015805182	5,10-methylene-tetrahydrofolate dehydrogenase [Actinosynnema mirum].	39.93	293	165	5	1	293	4	285	4e-59	202
rs:WP_039394729	methenyltetrahydrofolate cyclohydrolase [Microbacterium mangrovi].	39.93	298	166	7	1	292	1	291	4e-59	202
rs:WP_009677920	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia neofelifaecis].	40.54	296	159	6	1	293	1	282	4e-59	202
sp:FOLD_BIFLO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.66	295	169	5	1	291	1	290	4e-59	202
rs:WP_026547520	methenyltetrahydrofolate cyclohydrolase [Arthrobacter nicotinovorans].	38.38	297	169	5	2	292	5	293	5e-59	202
rs:XP_009643164	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Egretta garzetta].	42.03	295	160	5	5	293	1	290	5e-59	213
rs:XP_007258275	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Astyanax mexicanus].	41.50	294	161	5	3	290	24	312	5e-59	213
rs:WP_028270504	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. UNC362MFTsu5.1].	39.93	298	166	6	2	293	4	294	5e-59	202
rs:XP_007258277	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X3 [Astyanax mexicanus].	41.50	294	161	5	3	290	24	312	5e-59	213
rs:WP_007238721	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia otitidis].	39.93	293	165	4	1	293	1	282	5e-59	202
rs:WP_007224617	5,10-methylene-tetrahydrofolate dehydrogenase [marine gamma proteobacterium HTCC2143].	36.73	294	171	3	1	293	1	280	5e-59	201
rs:WP_041820823	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces davawensis].	38.68	287	162	2	7	293	4	276	5e-59	201
rs:WP_031958098	bifunctional protein FolD [Acinetobacter baumannii].	38.01	292	168	4	3	293	2	281	5e-59	201
rs:WP_004840297	bifunctional protein FolD [Acinetobacter baumannii].	38.01	292	168	4	3	293	2	281	5e-59	201
rs:XP_011833718	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Mandrillus leucophaeus].	41.61	286	157	5	3	283	112	392	5e-59	214
rs:WP_016655338	FolD protein [Acinetobacter rudis].	39.04	292	165	5	3	293	2	281	5e-59	201
tr:S7SZS9_9BACI	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:EPR29705.1}; EC=1.5.1.5 {ECO:0000313|EMBL:EPR29705.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EPR29705.1};	52.00	200	86	3	92	291	1	190	5e-59	199
rs:XP_010204945	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Colius striatus].	53.23	201	87	3	101	295	4	203	5e-59	199
tr:K4QWS8_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.68	287	162	2	7	293	21	293	5e-59	202
tr:K1ZM38_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.54	301	165	4	4	290	3	297	5e-59	202
rs:XP_009958161	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like, partial [Leptosomus discolor].	42.75	262	142	3	34	291	10	267	5e-59	202
rs:WP_032052813	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	38.01	292	168	4	3	293	2	281	5e-59	201
tr:A0A061SEP0_9CHLO	SubName: Full=5,10-methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:JAC81534.1}; Flags: Fragment;	36.76	340	165	4	2	293	72	409	5e-59	205
rs:WP_007069566	5,10-methylene-tetrahydrofolate dehydrogenase [Dialister invisus].	40.62	288	159	3	5	292	2	277	5e-59	201
rs:WP_034247980	methenyltetrahydrofolate cyclohydrolase [Actinotalea fermentans].	40.40	297	168	6	1	293	1	292	5e-59	202
rs:WP_040166614	methenyltetrahydrofolate cyclohydrolase [Microbacterium sp. G3].	40.69	290	159	6	1	284	1	283	5e-59	202
sp:FOLD_BIFLD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.00	290	165	5	6	291	5	289	6e-59	202
rs:WP_019532389	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora arenicola].	37.06	286	166	2	6	291	1	272	6e-59	201
rs:WP_017177178	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces timonensis].	39.06	297	168	6	2	292	8	297	6e-59	202
rs:WP_020394788	hypothetical protein [Thiothrix disciformis].	40.00	290	160	2	1	290	1	276	6e-59	201
rs:XP_010394474	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Corvus cornix cornix].	41.55	296	162	5	4	293	2	292	6e-59	213
rs:WP_035416718	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Chlamydia pneumoniae].	49.76	205	101	2	82	285	14	217	6e-59	199
rs:XP_008850342	PREDICTED: LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic [Nannospalax galili].	40.54	296	167	4	3	293	4	295	6e-59	213
rs:WP_040594030	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium metallidurans].	40.21	291	164	5	6	294	10	292	6e-59	202
rs:WP_030264325	methenyltetrahydrofolate cyclohydrolase [Streptacidiphilus jeojiense].	40.75	292	163	5	1	292	1	282	6e-59	201
rs:WP_030607614	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces achromogenes].	37.33	292	169	2	2	293	6	283	6e-59	201
rs:WP_004948905	FolD 2 [Acinetobacter soli].	37.80	291	170	2	3	293	2	281	6e-59	201
rs:WP_028707319	methenyltetrahydrofolate cyclohydrolase [Propionicicella superfundia].	42.66	286	153	4	1	286	1	275	6e-59	201
rs:WP_008249804	5,10-methylene-tetrahydrofolate dehydrogenase [gamma proteobacterium BDW918].	37.76	294	168	3	1	293	1	280	6e-59	201
rs:WP_010839294	methylenetetrahydrofolate dehydrogenase [Rhodococcus rhodnii].	40.21	291	164	4	1	291	1	281	7e-59	201
rs:WP_039209261	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	38.01	292	168	4	3	293	2	281	7e-59	201
rs:XP_007460122	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Lipotes vexillifer].	39.86	296	169	4	3	293	4	295	7e-59	213
rs:WP_019878507	hypothetical protein [Succinispira mobilis].	42.31	286	148	5	5	286	3	275	7e-59	201
rs:WP_037817411	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase, partial [Actinomycetales].	40.41	292	161	6	2	292	4	283	7e-59	201
tr:X1N868_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S18426 {ECO:0000313|EMBL:GAI39803.1}; Flags: Fragment;	46.50	200	107	0	41	240	1	200	7e-59	199
rs:WP_030983417	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-1813].	38.31	295	168	2	2	296	4	284	7e-59	201
rs:WP_004008177	5,10-methylene-tetrahydrofolate dehydrogenase [Mobiluncus curtisii].	38.44	294	172	6	3	292	9	297	7e-59	202
rs:WP_030042818	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces resistomycificus].	38.06	289	165	2	3	291	4	278	7e-59	201
rs:WP_030937837	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-646].	38.14	291	166	2	3	293	4	280	7e-59	201
rs:XP_006688522	tetrahydrofolate synthase [Candida tenuis ATCC 10573].	41.98	293	160	5	3	290	2	289	7e-59	213
tr:M5EW70_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.21	291	164	5	6	294	23	305	7e-59	202
tr:S2WE04_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.13	299	168	6	1	293	1	291	7e-59	202
rs:WP_004858939	FolD protein [Acinetobacter gerneri].	38.36	292	167	4	3	293	2	281	7e-59	201
tr:A0A097ATL2_THEKI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.60	289	151	5	5	292	4	281	7e-59	201
rs:WP_036860719	5,10-methylene-tetrahydrofolate cyclohydrolase [Porticoccus hydrocarbonoclasticus].	37.41	294	169	3	1	293	1	280	7e-59	201
rs:WP_001229851	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter baumannii].	38.01	292	168	4	3	293	2	281	7e-59	201
rs:WP_042395979	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptacidiphilus carbonis].	39.04	292	162	4	2	292	12	288	8e-59	201
rs:XP_009012138	hypothetical protein HELRODRAFT_104956 [Helobdella robusta].	42.91	296	160	4	3	293	2	293	8e-59	213
rs:WP_034684315	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	38.01	292	168	4	3	293	2	281	8e-59	201
rs:XP_009496528	formate-tetrahydrofolate ligase [Fonticula alba].	43.80	242	130	2	54	293	2	239	8e-59	205
rs:WP_018540994	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. MspMP-M5].	39.04	292	164	2	2	293	8	285	8e-59	201
rs:WP_025470003	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	38.01	292	168	4	3	293	2	281	8e-59	201
rs:WP_037889490	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-87].	39.24	288	161	2	6	293	1	274	8e-59	201
rs:WP_016167035	FolD 2 [Acinetobacter tandoii].	38.01	292	168	4	3	293	2	281	8e-59	201
rs:WP_001229848	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter baumannii].	38.01	292	168	4	3	293	2	281	9e-59	201
rs:WP_009166790	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus florum].	41.05	285	155	4	4	286	3	276	9e-59	201
rs:WP_019793443	hypothetical protein, partial [Streptococcus sobrinus].	51.53	196	85	2	98	293	1	186	9e-59	198
rs:WP_039252996	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	38.01	292	168	4	3	293	2	281	9e-59	201
tr:A9NZF4_PICSI	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:ABK26015.1};	42.19	256	142	2	3	256	2	253	9e-59	201
rs:WP_036920318	5,10-methylene-tetrahydrofolate cyclohydrolase [Prochlorococcus marinus].	43.55	287	155	3	6	291	5	285	9e-59	201
rs:WP_031220236	methenyltetrahydrofolate cyclohydrolase [Streptomycetaceae bacterium MP113-05].	39.80	294	163	6	1	292	1	282	9e-59	201
rs:WP_028990951	5,10-methylene-tetrahydrofolate cyclohydrolase [Thermacetogenium phaeum].	39.25	293	163	5	1	291	1	280	9e-59	201
rs:XP_007207779	hypothetical protein PRUPE_ppa026117mg [Prunus persica].	38.75	289	169	3	6	292	1	283	1e-58	201
rs:WP_037889759	methenyltetrahydrofolate cyclohydrolase, partial [Streptomyces sp. NRRL S-87].	41.10	292	162	5	1	292	1	282	1e-58	201
rs:WP_043586121	methenyltetrahydrofolate cyclohydrolase [Clavibacter michiganensis].	38.98	295	171	6	1	291	1	290	1e-58	201
rs:WP_010113182	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter sp. P8-3-8].	38.36	292	167	4	3	293	2	281	1e-58	201
rs:XP_012404134	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Sarcophilus harrisii].	43.84	276	141	4	19	290	1	266	1e-58	212
rs:WP_033513335	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium catenulatum].	39.73	292	167	5	6	293	5	291	1e-58	201
rs:WP_029348375	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium ciceri].	39.72	287	166	3	6	292	10	289	1e-58	201
rs:WP_038477548	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus lehensis].	38.33	287	162	4	5	291	6	277	1e-58	201
rs:WP_042915870	methenyltetrahydrofolate cyclohydrolase [Mycobacterium canettii].	39.86	291	164	4	1	291	1	280	1e-58	201
rs:WP_036277117	methenyltetrahydrofolate cyclohydrolase [Microbacterium sp. CH12i].	39.66	295	169	6	1	291	1	290	1e-58	201
rs:WP_028548605	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. UNC451MF].	38.68	287	161	4	5	291	4	275	1e-58	201
tr:U4U523_DENPD	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERL85070.1};	42.18	294	162	4	3	292	6	295	1e-58	212
rs:WP_006548550	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces urogenitalis].	38.44	294	172	6	2	291	8	296	1e-58	201
rs:WP_032735198	bifunctional protein FolD [Bifidobacterium longum].	39.66	290	166	5	6	291	5	289	1e-58	201
rs:WP_005806071	MULTISPECIES: methylenetetrahydrofolate dehydrogenase [Candidatus Arthromitus].	42.29	253	135	2	36	288	35	276	1e-58	201
rs:WP_035914885	methenyltetrahydrofolate cyclohydrolase [Knoellia sinensis].	39.04	292	167	6	1	291	1	282	1e-58	201
rs:WP_010155043	5,10-methylene-tetrahydrofolate dehydrogenase [Leucobacter chromiiresistens].	39.53	296	170	6	1	292	1	291	1e-58	201
rs:WP_004601086	5,10-methylene-tetrahydrofolate dehydrogenase [Turicella otitidis].	39.73	292	165	4	2	293	9	289	1e-58	201
rs:WP_035266915	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter sp. Ver3].	38.36	292	167	4	3	293	2	281	1e-58	201
rs:WP_034802035	methenyltetrahydrofolate cyclohydrolase [Intrasporangium oryzae].	38.57	293	167	5	1	293	1	280	1e-58	201
rs:WP_035507774	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus iners].	40.43	282	156	4	9	290	4	273	1e-58	201
rs:WP_036346073	methenyltetrahydrofolate cyclohydrolase [Mycobacterium aromaticivorans].	40.00	295	160	5	1	292	1	281	1e-58	201
tr:A0A024G5S1_9STRA	SubName: Full=Albugo candida WGS project CAIX00000000 data, strain Ac Nc2, contig AcNc2_CONTIG_29_length_140563 {ECO:0000313|EMBL:CCI42112.1};	40.23	261	148	3	34	292	404	658	1e-58	209
tr:N6SYK6_DENPD	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ENN72864.1, ECO:0000313|EnsemblMetazoa:ENN72864}; Flags: Fragment;	42.18	294	162	4	3	292	6	295	1e-58	212
tr:S2PUD6_LACPA	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EPC56015.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EPC56015.1}; Flags: Fragment;	47.21	233	113	2	59	291	1	223	1e-58	199
rs:WP_027097694	methenyltetrahydrofolate cyclohydrolase [Clostridium paraputrificum].	39.79	289	163	2	3	291	2	279	1e-58	201
rs:WP_004009905	5,10-methylene-tetrahydrofolate dehydrogenase [Mobiluncus curtisii].	38.44	294	172	6	3	292	9	297	1e-58	201
rs:WP_047329358	methenyltetrahydrofolate cyclohydrolase [Mycobacterium sp. EPa45].	39.66	295	161	5	1	292	1	281	1e-58	201
rs:WP_030670104	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL B-1347].	37.11	291	169	2	3	293	10	286	1e-58	201
rs:XP_007102341	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Physeter catodon].	39.53	296	170	4	3	293	4	295	1e-58	211
rs:XP_006102630	PREDICTED: LOW QUALITY PROTEIN: c-1-tetrahydrofolate synthase, cytoplasmic [Myotis lucifugus].	41.22	296	162	5	3	293	4	292	1e-58	211
tr:M2ZGC1_9NOCA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.89	291	161	4	1	291	1	280	1e-58	201
rs:WP_029090222	methenyltetrahydrofolate cyclohydrolase [Brevibacterium album].	38.23	293	168	6	6	292	3	288	1e-58	201
rs:WP_042401015	methenyltetrahydrofolate cyclohydrolase [Streptacidiphilus carbonis].	40.07	292	165	4	1	292	1	282	1e-58	201
rs:WP_045715344	methenyltetrahydrofolate cyclohydrolase, partial [Salmonella enterica].	50.48	210	100	1	1	210	1	206	1e-58	198
tr:M2XN94_9NOCA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.61	293	163	4	1	293	1	282	1e-58	201
rs:WP_040520547	methenyltetrahydrofolate cyclohydrolase [Gordonia malaquae].	41.26	286	157	5	1	286	1	275	1e-58	201
rs:WP_003713438	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus oris].	41.26	286	155	4	3	286	2	276	1e-58	201
rs:WP_024452764	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Mycobacterium].	40.20	296	160	5	1	293	1	282	1e-58	201
rs:WP_005234671	MULTISPECIES: FolD 2 [Acinetobacter].	38.36	292	167	4	3	293	2	281	1e-58	200
rs:WP_025094340	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter soli].	37.80	291	170	2	3	293	2	281	1e-58	200
sp:FOLD2_ACIAD	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.36	292	167	4	3	293	2	281	1e-58	200
tr:V6L4X6_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.80	294	163	6	1	292	4	285	1e-58	201
rs:WP_004279467	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter lwoffii].	38.36	292	167	4	3	293	2	281	1e-58	200
tr:A0A091HDI6_BUCRH	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFO92795.1}; Flags: Fragment;	41.75	285	155	5	15	293	5	284	2e-58	211
rs:WP_006501565	5,10-methylene-tetrahydrofolate dehydrogenase [Austwickia chelonae].	38.01	292	168	5	1	292	1	279	2e-58	200
rs:WP_027951033	5,10-methylene-tetrahydrofolate cyclohydrolase [Haliea salexigens].	38.10	294	167	3	1	293	1	280	2e-58	200
rs:WP_032547884	methenyltetrahydrofolate cyclohydrolase, partial [Vibrio cyclitrophicus].	51.00	200	94	1	1	200	1	196	2e-58	197
rs:WP_044636044	methenyltetrahydrofolate cyclohydrolase [Propionibacterium freudenreichii].	40.55	291	162	4	1	291	1	280	2e-58	200
rs:WP_026644998	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium sp. AGR2158].	39.53	296	165	6	3	292	2	289	2e-58	201
rs:WP_020834001	methylenetetrahydrofolate dehydrogenase [Spiroplasma taiwanense].	37.06	286	167	3	1	286	1	273	2e-58	200
tr:C3JGL0_RHOER	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.89	291	161	4	1	291	1	280	2e-58	200
rs:WP_043662276	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces xylophagus].	37.80	291	167	2	3	293	4	280	2e-58	200
rs:WP_044740778	5,10-methylene-tetrahydrofolate cyclohydrolase [Bacillus mycoides].	37.67	292	169	4	3	293	2	281	2e-58	200
sp:FOLD_MARMS	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	35.49	293	175	2	1	293	1	279	2e-58	200
rs:WP_017707346	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas syringae].	44.59	231	124	1	1	231	1	227	2e-58	198
tr:A0A0D9LEP1_9EURO	SubName: Full=Formate-tetrahydrofolate ligase FTHFS {ECO:0000313|EMBL:KJJ13023.1};	42.18	294	154	5	1	290	1	282	2e-58	211
tr:K4LFR1_THEPS	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.25	293	163	5	1	291	21	300	2e-58	201
tr:A0A094Q3R4_9ZZZZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGA16729.1};	39.58	288	163	5	3	290	4	280	2e-58	200
rs:WP_039364349	methenyltetrahydrofolate cyclohydrolase [Mumia flava].	40.56	286	160	4	1	286	1	276	2e-58	200
rs:XP_010139372	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Buceros rhinoceros silvestris].	41.75	285	155	5	15	293	2	281	2e-58	211
rs:WP_025362770	hypothetical protein [Spiroplasma culicicola].	38.97	290	164	3	4	293	5	281	2e-58	200
rs:WP_017626034	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis chromatogenes].	41.90	284	154	5	1	284	1	273	2e-58	200
tr:A0A0C3AVD4_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIM28505.1};	38.39	323	161	7	3	291	7	325	2e-58	211
rs:WP_030485067	methenyltetrahydrofolate cyclohydrolase [Marmoricola aequoreus].	39.36	282	160	4	1	282	1	271	2e-58	200
rs:WP_017542230	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis prasina].	40.75	292	162	5	1	292	1	281	2e-58	200
rs:WP_019609758	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis sp. CNS639].	41.10	292	161	5	1	292	1	281	2e-58	200
rs:WP_034094078	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptacidiphilus albus].	38.46	286	162	2	6	291	1	272	2e-58	200
rs:WP_005030715	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter bereziniae].	38.70	292	166	5	3	293	2	281	2e-58	200
rs:WP_010525722	5,10-methylene-tetrahydrofolate dehydrogenase [Nesterenkonia sp. F].	39.26	298	168	6	1	292	7	297	2e-58	201
rs:WP_039134612	methenyltetrahydrofolate cyclohydrolase, partial [Leisingera sp. ANG-Vp].	46.15	247	122	3	48	292	1	238	2e-58	199
rs:WP_031202532	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. L103C120A0].	39.93	288	164	4	6	292	10	289	2e-58	200
rs:WP_029679263	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium longum].	40.00	295	167	6	1	291	1	289	2e-58	200
tr:X1J073_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S12647 {ECO:0000313|EMBL:GAH63203.1}; Flags: Fragment;	42.62	244	126	3	50	290	1	233	2e-58	198
rs:WP_045795204	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter indicus].	38.36	292	167	5	3	293	2	281	2e-58	200
rs:WP_028473363	methenyltetrahydrofolate cyclohydrolase [Nocardioides alkalitolerans].	40.75	292	162	4	1	292	1	281	2e-58	200
tr:A0A023F1A8_TRIIF	SubName: Full=Putative c1-tetrahydrofolate synthase {ECO:0000313|EMBL:JAC15260.1}; Flags: Fragment;	38.39	310	167	6	1	290	2	307	2e-58	201
tr:W4LQ87_9DELT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.11	291	174	3	1	291	1	282	2e-58	200
rs:XP_004244965	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X8 [Solanum lycopersicum].	40.75	292	140	3	2	293	25	283	2e-58	200
rs:WP_002597722	hypothetical protein [Clostridium colicanis].	36.68	289	172	2	4	292	3	280	2e-58	200
rs:WP_033488783	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium pseudolongum].	40.82	294	165	6	3	292	2	290	2e-58	200
rs:XP_003956155	hypothetical protein KAFR_0C00240 [Kazachstania africana CBS 2517].	44.03	293	156	4	5	293	9	297	2e-58	211
rs:WP_007123396	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus antri].	41.26	286	155	4	3	286	2	276	2e-58	200
rs:XP_010213151	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Tinamus guttatus].	42.11	285	154	5	15	293	2	281	2e-58	211
rs:WP_013160601	5,10-methylene-tetrahydrofolate dehydrogenase [Propionibacterium freudenreichii].	40.55	291	162	4	1	291	1	280	2e-58	200
rs:WP_004751261	MULTISPECIES: FolD protein [Acinetobacter].	38.01	292	168	4	3	293	2	281	2e-58	200
rs:WP_026420991	methenyltetrahydrofolate cyclohydrolase [Actinobaculum urinale].	41.02	295	165	6	2	292	7	296	2e-58	200
tr:N9JAK6_ACIBA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.01	292	168	4	3	293	32	311	2e-58	201
rs:WP_004770373	FolD protein [Acinetobacter sp. NIPH 758].	38.01	292	168	4	3	293	2	281	2e-58	200
tr:V7G050_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.61	274	151	4	19	291	4	269	2e-58	200
rs:WP_022886047	5,10-methylene-tetrahydrofolate dehydrogenase [Glaciibacter superstes].	38.72	297	173	6	1	293	1	292	3e-58	200
rs:WP_046733409	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. MUSC119T].	37.46	291	168	2	3	293	4	280	3e-58	200
rs:XP_002911870	C-1-tetrahydrofolate synthase [Coprinopsis cinerea okayama7#130].	40.71	312	157	5	2	289	4	311	3e-58	211
rs:WP_034586353	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter sp. HR7].	38.01	292	168	4	3	293	2	281	3e-58	200
gp:HB883541_1	Sequence 16216 from Patent EP2096177. [Eremothecium gossypii]	41.38	290	163	3	5	291	3	288	3e-58	211
rs:WP_008289584	methylenetetrahydrofolate dehydrogenase, partial [Hydrogenivirga sp. 128-5-R1-1].	47.62	210	106	2	3	211	2	208	3e-58	197
rs:WP_040973973	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. ORS3324].	40.07	287	165	3	6	292	10	289	3e-58	200
rs:WP_004990201	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter].	38.01	292	168	4	3	293	2	281	3e-58	199
rs:WP_005259091	FolD protein [Acinetobacter sp. NIPH 2168].	38.01	292	168	4	3	293	2	281	3e-58	199
rs:WP_004782941	FolD 2 [Acinetobacter sp. NIPH 899].	38.36	292	167	4	3	293	2	281	3e-58	199
rs:XP_002422948	formate-tetrahydrofolate ligase, putative [Pediculus humanus corporis].	40.61	293	166	4	5	293	10	298	3e-58	211
rs:WP_024615039	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. Ade.TY].	38.28	290	168	2	3	292	2	280	3e-58	199
rs:WP_034704935	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	38.36	292	167	4	3	293	2	281	3e-58	199
rs:WP_024035826	bifunctional protein FolD [Actinomyces urogenitalis].	38.44	294	172	6	2	291	8	296	3e-58	200
rs:WP_008301933	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter sp. HA].	38.01	292	168	4	3	293	2	281	3e-58	199
rs:WP_004878340	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter].	38.01	292	168	4	3	293	2	281	3e-58	199
tr:H0ZRS8_TAEGU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTGUP00000013322}; Flags: Fragment;	42.46	285	153	5	15	293	2	281	3e-58	211
rs:WP_045529517	methenyltetrahydrofolate cyclohydrolase [Clavibacter michiganensis].	38.64	295	172	6	1	291	1	290	3e-58	200
rs:XP_001017646	methylene-tetrahydrofolate dehydrogenase/cyclohydrolase NADP-binding domain protein [Tetrahymena thermophila SB210].	38.38	297	166	7	1	291	14	299	3e-58	201
rs:WP_046824271	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. JC272].	38.14	291	168	5	1	290	6	285	3e-58	200
tr:M9MVJ0_ASHG1	SubName: Full=FACL121Cp {ECO:0000313|EMBL:AEY95397.1};	41.38	290	163	3	5	291	3	288	3e-58	211
rs:WP_027740084	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. CNT360].	38.41	289	164	2	5	293	1	275	3e-58	199
rs:XP_003017742	hypothetical protein ARB_04625 [Arthroderma benhamiae CBS 112371].	41.64	293	157	5	1	290	88	369	3e-58	211
rs:WP_039414132	methenyltetrahydrofolate cyclohydrolase [Microbacterium hominis].	39.33	300	167	8	1	293	1	292	3e-58	200
rs:WP_017703795	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Pseudomonas syringae].	45.76	236	121	2	59	294	9	237	3e-58	198
rs:WP_005171937	FolD 2 [Acinetobacter sp. NIPH 713].	38.36	292	167	4	3	293	2	281	3e-58	199
tr:A0A061S7G5_9CHLO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:JAC78716.1}; Flags: Fragment;	43.60	250	135	2	3	250	58	303	3e-58	200
tr:R0JPE3_ANAPL	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:EOA99021.1}; Flags: Fragment;	42.25	284	155	4	15	293	2	281	3e-58	210
rs:XP_012593628	PREDICTED: LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic-like [Microcebus murinus].	40.96	293	164	4	3	290	4	292	3e-58	210
rs:XP_012633217	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Microcebus murinus].	44.53	256	134	3	39	290	43	294	3e-58	210
rs:WP_017564065	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Nocardiopsis synnemataformans].	41.44	292	160	5	1	292	1	281	4e-58	199
rs:WP_040666900	methenyltetrahydrofolate cyclohydrolase, partial [Nitrolancea hollandica].	42.51	287	153	3	3	289	2	276	4e-58	199
rs:WP_036312980	methenyltetrahydrofolate cyclohydrolase [Microbacterium oleivorans].	40.88	296	166	6	1	292	1	291	4e-58	200
tr:A0A091JW28_COLST	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFP28093.1}; Flags: Fragment;	53.81	197	84	3	101	291	1	196	4e-58	196
rs:WP_027156347	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. WSM2561].	39.02	287	168	3	6	292	10	289	4e-58	200
rs:WP_021431735	tetrahydrofolate dehydrogenase [[Clostridium] bifermentans].	38.14	291	168	5	1	290	6	285	4e-58	199
rs:WP_036968491	methenyltetrahydrofolate cyclohydrolase [Promicromonospora kroppenstedtii].	39.13	299	173	5	1	295	1	294	4e-58	199
rs:WP_026360355	methenyltetrahydrofolate cyclohydrolase [Amycolatopsis nigrescens].	38.01	292	170	4	1	292	1	281	4e-58	199
rs:WP_009585645	tetrahydrofolate dehydrogenase [Acinetobacter sp. WC-743].	38.70	292	166	5	3	293	2	281	4e-58	199
rs:WP_018682706	5,10-methylene-tetrahydrofolate dehydrogenase [Actinokineospora enzanensis].	40.27	293	164	5	1	293	1	282	4e-58	199
rs:WP_016463122	FolD protein [Bifidobacterium breve].	40.21	291	165	5	6	292	5	290	4e-58	199
rs:WP_019738026	5,10-methylene-tetrahydrofolate dehydrogenase [Mycobacterium avium].	39.04	292	167	5	1	292	1	281	4e-58	199
rs:WP_017823813	5,10-methylene-tetrahydrofolate dehydrogenase [Brachybacterium muris].	41.89	296	164	5	1	292	1	292	4e-58	200
gp:AE015927_1411	methylenetetrahydrofolate dehydrogenase [Clostridium tetani E88]	39.84	256	143	3	29	284	11	255	4e-58	198
rs:WP_022956080	5,10-methylene-tetrahydrofolate dehydrogenase [Perlucidibaca piscinae].	37.20	293	170	2	1	293	1	279	4e-58	199
rs:NP_983283	ACL121Cp [Ashbya gossypii ATCC 10895].	41.38	290	163	3	5	291	3	288	4e-58	210
rs:WP_005015677	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter].	37.67	292	169	4	3	293	2	281	4e-58	199
rs:WP_005406102	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter].	37.67	292	169	4	3	293	2	281	4e-58	199
rs:WP_027945800	methenyltetrahydrofolate cyclohydrolase [Amycolatopsis taiwanensis].	37.63	295	173	4	1	295	1	284	4e-58	199
rs:WP_004828322	FolD protein [Acinetobacter bereziniae].	38.14	291	169	3	3	293	2	281	4e-58	199
rs:WP_008417944	5,10-methylene-tetrahydrofolate dehydrogenase [Clostridium sp. Maddingley MBC34-26].	37.67	292	171	2	3	294	2	282	4e-58	199
rs:WP_040476362	methenyltetrahydrofolate cyclohydrolase, partial [Magnetospirillum sp. SO-1].	39.92	258	149	2	31	288	25	276	5e-58	199
rs:WP_045792790	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter brisouii].	37.67	292	169	4	3	293	2	281	5e-58	199
rs:WP_005555758	5,10-methylene-tetrahydrofolate dehydrogenase [Natronococcus amylolyticus].	38.83	291	173	2	1	291	1	286	5e-58	199
tr:A0A091SJW1_9GRUI	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFQ40570.1}; Flags: Fragment;	42.11	285	154	5	15	293	2	281	5e-58	210
rs:WP_004012881	5,10-methylene-tetrahydrofolate dehydrogenase [Mobiluncus mulieris].	37.37	297	177	6	2	294	8	299	5e-58	199
rs:WP_031201082	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. LSJC265A00].	40.28	288	163	4	6	292	10	289	5e-58	200
rs:WP_014436911	5,10-methylene-tetrahydrofolate dehydrogenase [Phycisphaera mikurensis].	40.07	292	159	4	1	291	1	277	5e-58	199
rs:WP_008362246	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardioidaceae bacterium Broad-1].	38.93	298	165	5	2	293	3	289	5e-58	199
rs:WP_033511048	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium mongoliense].	39.93	293	167	5	5	293	4	291	5e-58	199
rs:WP_020016299	5,10-methylene-tetrahydrofolate dehydrogenase [Promicromonospora sukumoe].	38.80	299	174	5	1	295	1	294	5e-58	199
rs:XP_006915178	PREDICTED: LOW QUALITY PROTEIN: c-1-tetrahydrofolate synthase, cytoplasmic [Pteropus alecto].	39.47	304	167	5	3	293	4	303	5e-58	210
rs:WP_026266658	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. 131MFCol6.1].	38.78	294	168	6	5	293	1	287	5e-58	199
tr:I4EGB6_9CHLR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.16	287	154	3	3	289	2	276	5e-58	199
rs:WP_029256932	methenyltetrahydrofolate cyclohydrolase [Rhodococcus erythropolis].	39.66	290	166	3	3	292	4	284	5e-58	199
rs:XP_004924493	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Bombyx mori].	42.16	287	158	4	11	293	11	293	5e-58	210
rs:WP_010833926	methenyltetrahydrofolate cyclohydrolase [Nocardioides sp. CF8].	38.70	292	166	5	1	292	1	279	5e-58	199
rs:XP_009075458	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Acanthisitta chloris].	42.11	285	154	5	15	293	2	281	5e-58	210
rs:WP_043168688	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium pullorum].	39.86	291	166	5	6	292	5	290	5e-58	199
rs:WP_006367531	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia polyisoprenivorans].	39.86	296	161	5	1	293	4	285	5e-58	199
tr:K4CKH6_SOLLC	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Solyc08g048240.2.1};	40.75	292	140	3	2	293	56	314	5e-58	200
rs:WP_013837983	5,10-methylene-tetrahydrofolate dehydrogenase [Isoptericola variabilis].	40.40	297	164	6	1	291	1	290	5e-58	199
rs:WP_022467004	bifunctional protein FolD [Subdoligranulum sp. CAG:314].	38.81	286	162	3	3	288	2	274	5e-58	199
rs:WP_043422821	methenyltetrahydrofolate cyclohydrolase, partial [Arthrobacter sp. 9MFCol3.1].	38.91	293	167	6	5	292	1	286	6e-58	199
rs:WP_010326278	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter lwoffii].	37.67	292	169	4	3	293	2	281	6e-58	199
rs:WP_017584064	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis valliformis].	40.07	292	164	4	1	292	1	281	6e-58	199
rs:XP_006134161	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Pelodiscus sinensis].	42.46	285	153	5	15	293	68	347	6e-58	210
tr:F6YIU8_HORSE	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000014168}; Flags: Fragment;	40.49	284	160	4	15	293	4	283	6e-58	210
rs:XP_005418079	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Geospiza fortis].	42.46	285	153	5	15	293	14	293	6e-58	209
rs:WP_030640870	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces].	37.46	291	168	2	3	293	4	280	6e-58	199
rs:WP_004810794	MULTISPECIES: FolD 2 [Acinetobacter].	38.01	292	168	4	3	293	2	281	6e-58	199
rs:WP_023716475	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. LSHC420B00].	39.02	287	168	3	6	292	10	289	6e-58	199
rs:WP_028496865	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Microbacterium].	41.08	297	166	6	1	293	1	292	6e-58	199
rs:WP_008426068	5,10-methylene-tetrahydrofolate dehydrogenase [Natronococcus jeotgali].	40.75	292	166	2	1	292	1	285	6e-58	199
rs:WP_033381259	5,10-methylene-tetrahydrofolate cyclohydrolase [Kibdelosporangium aridum].	37.54	293	167	3	5	297	3	279	6e-58	199
tr:H0WRN6_OTOGA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOGAP00000004699}; Flags: Fragment;	40.14	284	161	4	15	293	13	292	6e-58	209
rs:WP_010831420	methenyltetrahydrofolate cyclohydrolase [Nocardioides sp. CF8].	39.31	290	165	4	3	292	5	283	6e-58	199
rs:WP_042994134	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium breve].	40.21	291	165	5	6	292	5	290	7e-58	199
rs:WP_005399859	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter johnsonii].	37.67	292	169	4	3	293	2	281	7e-58	199
rs:XP_003019736	hypothetical protein TRV_06219 [Trichophyton verrucosum HKI 0517].	41.64	293	157	5	1	290	88	369	7e-58	211
rs:WP_027160988	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. WSM1293].	40.37	270	152	4	27	294	31	293	7e-58	199
rs:WP_030172613	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-813].	37.11	291	169	3	3	293	4	280	7e-58	199
rs:WP_025221430	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium breve].	40.07	292	166	5	5	292	4	290	7e-58	199
rs:WP_035100161	methenyltetrahydrofolate cyclohydrolase [Devosia sp. LC5].	42.51	287	154	4	3	289	6	281	7e-58	199
rs:XP_007068064	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Chelonia mydas].	41.75	285	155	5	15	293	1	280	7e-58	209
rs:WP_007147382	5,10-methylene-tetrahydrofolate dehydrogenase [Scardovia wiggsiae].	39.18	291	168	5	5	291	4	289	7e-58	199
rs:WP_042759019	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Acinetobacter baumannii].	38.33	287	164	4	3	288	2	276	7e-58	198
rs:WP_029507566	5,10-methylene-tetrahydrofolate cyclohydrolase [Lactobacillus coryniformis].	40.97	288	159	3	5	292	3	279	7e-58	199
rs:WP_004912747	FolD protein [Acinetobacter junii].	38.36	292	167	4	3	293	2	281	8e-58	198
rs:XP_011466895	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X2 [Fragaria vesca subsp. vesca].	41.44	292	165	2	3	292	45	332	8e-58	200
rs:WP_005158123	FolD protein [Acinetobacter sp. NIPH 284].	38.01	292	168	4	3	293	2	281	8e-58	198
rs:WP_017679627	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodococcus ruber].	40.55	291	162	4	1	291	4	283	8e-58	199
tr:W9B5A9_9MYCO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.86	296	161	5	1	293	4	285	8e-58	199
rs:WP_047313406	methenyltetrahydrofolate cyclohydrolase [Mycobacterium haemophilum].	40.14	284	159	5	1	284	1	273	8e-58	198
rs:WP_028929251	methenyltetrahydrofolate cyclohydrolase [Pseudonocardia asaccharolytica].	39.93	293	165	4	1	293	1	282	8e-58	199
rs:XP_011774470	C-1-tetrahydrofolate synthase, cytoplasmic,putative [Trypanosoma brucei gambiense DAL972].	38.72	297	171	5	3	293	4	295	8e-58	199
rs:WP_019126277	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces sp. ph3].	39.12	294	170	6	3	292	9	297	8e-58	199
tr:A0A091LN26_CARIC	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFP60596.1}; Flags: Fragment;	42.11	285	154	5	15	293	2	281	8e-58	209
rs:WP_040783354	methenyltetrahydrofolate cyclohydrolase [Rhodococcus ruber].	40.55	291	162	4	1	291	4	283	8e-58	199
rs:WP_027035567	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium ciceri].	40.37	270	152	4	27	294	31	293	8e-58	199
rs:WP_016669477	methylenetetrahydrofolate dehydrogenase [Propionibacterium sp. oral taxon 192].	39.73	292	165	4	1	292	1	281	8e-58	198
rs:XP_001432814	hypothetical protein [Paramecium tetraurelia strain d4-2].	45.38	260	125	6	34	291	141	385	8e-58	202
rs:XP_002019868	GL11980 [Drosophila persimilis].	42.03	295	163	4	3	293	40	330	8e-58	209
rs:XP_004287199	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X1 [Fragaria vesca subsp. vesca].	41.44	292	165	2	3	292	46	333	8e-58	200
rs:WP_030532786	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Prauserella].	38.70	292	168	4	1	292	1	281	8e-58	198
rs:WP_005937334	bifunctional protein FolD [Gordonia hirsuta].	40.85	284	151	6	6	286	12	281	8e-58	199
rs:WP_012833579	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia bronchialis].	40.61	293	158	6	6	292	9	291	8e-58	199
tr:A0A069DI88_9BACL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.06	289	164	4	5	293	7	280	8e-58	198
rs:WP_004674908	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter].	38.01	292	168	4	3	293	2	281	8e-58	198
tr:A0A0C6EEQ6_9BIFI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.73	292	167	5	6	293	8	294	8e-58	199
rs:WP_014464471	methenyltetrahydrofolate cyclohydrolase [Alicyclobacillus acidocaldarius].	39.44	284	159	4	3	286	2	272	8e-58	198
rs:XP_001360009	GA13173 [Drosophila pseudoobscura pseudoobscura].	42.03	295	163	4	3	293	40	330	8e-58	209
rs:WP_030434044	methenyltetrahydrofolate cyclohydrolase [Actinoplanes subtropicus].	37.33	292	174	3	1	292	1	283	8e-58	198
rs:XP_008955977	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Pan paniscus].	44.06	261	139	3	3	257	154	413	9e-58	203
rs:WP_045245877	methenyltetrahydrofolate cyclohydrolase [Microbacterium ginsengisoli].	39.33	300	167	7	1	293	1	292	9e-58	199
rs:WP_007319086	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia effusa].	40.48	289	155	6	1	286	1	275	9e-58	198
rs:XP_002390175	hypothetical protein MPER_10594 [Moniliophthora perniciosa FA553].	45.68	243	123	3	54	291	2	240	9e-58	205
rs:WP_005189704	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia amarae].	40.07	297	159	7	1	293	1	282	9e-58	198
rs:WP_020008018	hypothetical protein [Salinicoccus albus].	39.59	293	165	4	5	296	4	285	9e-58	199
rs:WP_007219912	methenyltetrahydrofolate cyclohydrolase [planctomycete KSU-1].	37.50	304	174	4	1	293	1	299	9e-58	199
tr:A0A091UEF6_PHORB	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFQ88532.1}; Flags: Fragment;	41.55	284	157	4	15	293	2	281	9e-58	209
rs:WP_033280309	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-525].	37.80	291	167	2	3	293	4	280	9e-58	198
rs:XP_009707687	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Cariama cristata].	42.11	285	154	5	15	293	45	324	9e-58	209
tr:A0A091SZ01_9AVES	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFQ63952.1}; Flags: Fragment;	41.70	283	154	5	15	291	2	279	9e-58	206
rs:WP_034266727	methenyltetrahydrofolate cyclohydrolase [Amycolatopsis halophila].	38.28	290	168	5	3	292	2	280	9e-58	198
rs:WP_017571320	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis halotolerans].	41.44	292	160	5	1	292	1	281	9e-58	198
rs:WP_042089294	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter bereziniae].	38.36	292	167	5	3	293	2	281	9e-58	198
rs:WP_027892416	methenyltetrahydrofolate cyclohydrolase [Meiothermus chliarophilus].	43.21	287	151	5	6	291	4	279	9e-58	198
rs:WP_005243532	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter].	38.01	292	168	4	3	293	2	281	1e-57	198
rs:XP_011895832	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X4 [Cercocebus atys].	40.60	298	128	3	3	294	51	305	1e-57	199
rs:XP_008955976	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Pan paniscus].	44.06	261	139	3	3	257	154	413	1e-57	203
rs:WP_031105599	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-146].	37.80	291	167	2	3	293	4	280	1e-57	198
rs:WP_014359508	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia polyisoprenivorans].	39.86	296	161	5	1	293	4	285	1e-57	199
tr:M3VC24_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.28	281	154	5	6	286	12	281	1e-57	198
rs:WP_021913626	MULTISPECIES: bifunctional protein FolD [Bifidobacterium].	39.38	292	168	5	6	293	5	291	1e-57	198
rs:XP_004837470	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Heterocephalus glaber].	41.90	284	156	4	15	293	33	312	1e-57	209
rs:XP_007997075	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Chlorocebus sabaeus].	43.23	266	144	3	3	262	51	315	1e-57	199
rs:WP_033501754	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium kashiwanohense].	39.73	292	167	5	6	293	5	291	1e-57	198
tr:L1QG67_9CLOT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.80	291	170	2	1	291	1	280	1e-57	198
rs:WP_022864792	5,10-methylene-tetrahydrofolate dehydrogenase [Varibaculum cambriense].	37.54	293	175	5	3	291	9	297	1e-57	199
rs:XP_011616925	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X4 [Takifugu rubripes].	44.81	241	123	4	56	291	2	237	1e-57	197
rs:WP_005096303	FolD 2 [Acinetobacter lwoffii].	38.01	292	168	4	3	293	2	281	1e-57	198
rs:WP_005025050	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter].	37.67	292	169	4	3	293	2	281	1e-57	198
rs:WP_014483887	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium breve].	40.20	296	167	6	1	292	1	290	1e-57	198
rs:WP_037851090	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-340].	38.49	291	165	2	3	293	4	280	1e-57	198
rs:WP_027019424	methenyltetrahydrofolate cyclohydrolase [Corynebacterium sputi].	40.82	294	155	6	1	290	1	279	1e-57	198
rs:WP_005081710	FolD protein [Acinetobacter haemolyticus].	38.36	292	167	5	3	293	2	281	1e-57	198
tr:F6EID4_AMYSD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.41	292	163	4	1	292	1	281	1e-57	198
rs:WP_013117721	5,10-methylene-tetrahydrofolate dehydrogenase [Cellulomonas flavigena].	40.68	295	166	5	1	291	1	290	1e-57	198
rs:WP_007288275	5,10-methylene-tetrahydrofolate dehydrogenase [Thermosinus carboxydivorans].	41.60	262	142	2	25	286	23	273	1e-57	198
rs:WP_037129092	methenyltetrahydrofolate cyclohydrolase [Rhodococcus erythropolis].	40.55	291	162	4	1	291	4	283	1e-57	198
rs:WP_020906983	MULTISPECIES: methylenetetrahydrofolate dehydrogenase [Rhodococcus].	40.27	293	164	4	1	293	4	285	1e-57	198
rs:WP_040282966	methenyltetrahydrofolate cyclohydrolase [Tessaracoccus sp. SIT6].	41.05	285	155	6	1	284	1	273	1e-57	198
rs:WP_023800351	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. L48C026A00].	39.16	286	167	3	6	291	10	288	1e-57	199
rs:WP_037734859	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces mirabilis].	37.46	291	168	2	3	293	4	280	1e-57	198
tr:X0YB44_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S38929 {ECO:0000313|EMBL:GAG53075.1}; Flags: Fragment;	45.58	226	110	3	70	293	3	217	1e-57	196
rs:XP_009918930	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Haliaeetus albicilla].	42.11	285	154	5	15	293	2	281	1e-57	209
rs:WP_026645816	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium ruminantium].	38.97	290	168	5	6	291	5	289	1e-57	198
rs:WP_030535088	methenyltetrahydrofolate cyclohydrolase [Rhodococcus erythropolis].	40.55	291	162	4	1	291	4	283	1e-57	198
rs:XP_001980661	GG17628 [Drosophila erecta].	41.69	295	164	4	3	293	38	328	1e-57	209
rs:WP_033413682	methenyltetrahydrofolate cyclohydrolase [Actinomycetospora chiangmaiensis].	39.73	292	165	4	1	292	4	284	1e-57	198
rs:WP_047012229	5,10-methylene-tetrahydrofolate cyclohydrolase [Spongiibacter sp. IMCC21906].	36.39	294	172	3	1	293	1	280	1e-57	198
rs:WP_033509286	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium saeculare].	39.52	291	167	5	6	292	5	290	1e-57	198
rs:WP_031243560	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. LNJC391B00].	40.07	287	163	4	6	291	10	288	1e-57	199
rs:WP_022898179	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Corynebacterium-like bacterium B27].	41.96	286	153	6	1	280	1	279	1e-57	198
rs:WP_043972575	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter sp. NBRC 110496].	38.01	292	168	4	3	293	2	281	1e-57	198
rs:WP_007321204	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia araii].	40.78	282	153	5	16	293	15	286	1e-57	198
rs:WP_004638297	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter haemolyticus].	38.36	292	167	5	3	293	2	281	1e-57	198
rs:WP_004956122	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter junii].	38.36	292	167	4	3	293	2	281	1e-57	198
rs:XP_006059705	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Bubalus bubalis].	40.60	298	128	3	3	294	51	305	1e-57	198
rs:XP_004891252	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Heterocephalus glaber].	41.55	284	157	4	15	293	33	312	1e-57	209
rs:WP_024058143	hypothetical protein [Varibaculum cambriense].	37.54	293	175	5	3	291	9	297	1e-57	198
rs:WP_039621563	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter harbinensis].	37.80	291	170	3	3	293	2	281	1e-57	197
rs:WP_014795430	methenyltetrahydrofolate cyclohydrolase [Desulfitobacterium dehalogenans].	38.28	290	167	4	4	292	3	281	2e-57	198
rs:XP_008070851	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Tarsius syrichta].	40.55	291	164	4	8	293	123	409	2e-57	209
rs:WP_023823635	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. L103C565B0].	40.07	287	163	4	6	291	10	288	2e-57	198
rs:WP_024542701	methenyltetrahydrofolate cyclohydrolase [actinobacterium SCGC AAA044-D11].	41.64	293	157	4	1	293	1	279	2e-57	197
rs:WP_022637606	5,10-methylene-tetrahydrofolate dehydrogenase [Chitinivibrio alkaliphilus].	39.10	289	162	4	3	291	2	276	2e-57	197
rs:WP_019891401	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces purpureus].	37.33	292	169	2	2	293	6	283	2e-57	197
rs:WP_026756406	methenyltetrahydrofolate cyclohydrolase [Sediminimonas qiaohouensis].	36.18	293	180	3	1	293	1	286	2e-57	198
rs:WP_039048033	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter junii].	38.36	292	167	4	3	293	2	281	2e-57	197
rs:WP_029540126	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Rhodococcus].	40.55	291	162	4	1	291	4	283	2e-57	198
rs:XP_001947803	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Acyrthosiphon pisum].	44.79	259	136	3	36	291	41	295	2e-57	209
rs:WP_030566733	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces cyaneofuscatus].	38.81	286	161	2	6	291	1	272	2e-57	197
rs:WP_004010421	5,10-methylene-tetrahydrofolate dehydrogenase [Mobiluncus curtisii].	38.10	294	173	6	3	292	9	297	2e-57	198
rs:WP_013873693	methenyltetrahydrofolate cyclohydrolase [Frankia symbiont of Datisca glomerata].	39.93	288	159	5	4	291	2	275	2e-57	197
rs:XP_002582842	C-1-tetrahydrofolate synthase [Uncinocarpus reesii 1704].	40.89	291	141	6	1	289	144	405	2e-57	209
sp:FOLD_BIFAA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.38	292	168	5	6	293	5	291	2e-57	198
rs:XP_845784	C-1-tetrahydrofolate synthase, cytoplasmic [Trypanosoma brucei TREU927].	38.38	297	172	5	3	293	4	295	2e-57	198
rs:XP_002103969	GD18702 [Drosophila simulans].	41.69	295	164	4	3	293	38	328	2e-57	209
rs:WP_013154967	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis dassonvillei].	41.10	292	161	5	1	292	1	281	2e-57	197
rs:XP_009271659	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Aptenodytes forsteri].	42.16	287	155	5	13	293	27	308	2e-57	209
rs:WP_026410377	methenyltetrahydrofolate cyclohydrolase [Actinomyces dentalis].	38.31	295	169	6	3	291	9	296	2e-57	198
rs:WP_016430677	FolD 1 [Streptomyces sp. HGB0020].	38.73	284	160	2	3	286	4	273	2e-57	197
rs:WP_008940893	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter].	38.36	292	167	5	3	293	2	281	2e-57	197
rs:WP_033506194	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium gallinarum].	39.52	291	167	5	6	292	5	290	2e-57	198
rs:WP_035011135	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium adolescentis].	39.38	292	168	5	6	293	5	291	2e-57	198
rs:WP_004017084	5,10-methylene-tetrahydrofolate dehydrogenase [Mobiluncus mulieris].	37.37	297	177	6	2	294	8	299	2e-57	198
tr:I3MPW2_SPETR	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSTOP00000013901}; Flags: Fragment;	44.36	257	135	3	41	293	1	253	2e-57	208
rs:WP_014446948	5,10-methylene-tetrahydrofolate dehydrogenase [Actinoplanes missouriensis].	37.33	292	174	3	1	292	1	283	2e-57	197
rs:WP_005184262	MULTISPECIES: FolD protein [Acinetobacter].	37.67	292	169	4	3	293	2	281	2e-57	197
rs:WP_004651323	FolD protein [Acinetobacter bohemicus].	38.01	292	168	4	3	293	2	281	2e-57	197
tr:G8BBJ3_CANPC	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CCE41508.1};	44.37	302	151	3	1	289	28	325	2e-57	209
tr:A0A091UUV8_NIPNI	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFQ94749.1}; Flags: Fragment;	41.75	285	155	5	15	293	2	281	2e-57	208
rs:XP_001924364	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Sus scrofa].	39.93	293	167	4	3	290	4	292	2e-57	208
rs:WP_017415714	hypothetical protein [Clostridium tunisiense].	39.24	288	164	2	6	293	5	281	2e-57	197
rs:XP_002414358	C1-tetrahydrofolate synthase, putative [Ixodes scapularis].	41.15	260	150	2	4	261	32	290	2e-57	198
rs:WP_030464907	5,10-methylene-tetrahydrofolate cyclohydrolase [Lechevalieria aerocolonigenes].	40.49	284	150	4	13	293	9	276	2e-57	197
tr:L8IEG4_9CETA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:ELR54616.1}; Flags: Fragment;	40.49	284	160	4	15	293	5	284	2e-57	208
rs:WP_019851245	methenyltetrahydrofolate cyclohydrolase [Desulfitobacterium sp. PCE1].	38.28	290	167	4	4	292	3	281	2e-57	197
tr:H0JKM4_9NOCA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.91	286	158	4	1	286	1	275	2e-57	197
rs:XP_010150555	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Eurypyga helias].	42.11	285	154	5	15	293	2	281	2e-57	207
tr:R1GQQ5_9GAMM	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EOD54015.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EOD54015.1};	50.00	192	86	2	99	290	1	182	2e-57	194
sp:FOLD_BIFA0	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.91	293	170	5	3	291	2	289	2e-57	198
rs:WP_005176331	FolD 2 [Acinetobacter sp. CIP 53.82].	38.36	292	167	5	3	293	2	281	2e-57	197
rs:WP_005231839	MULTISPECIES: FolD protein [Acinetobacter].	37.67	292	169	4	3	293	2	281	2e-57	197
tr:A0A094KUB2_ANTCR	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFZ62170.1}; Flags: Fragment;	41.75	285	155	5	15	293	2	281	2e-57	208
rs:WP_021428489	tetrahydrofolate dehydrogenase [[Clostridium] bifermentans].	38.14	291	168	5	1	290	6	285	2e-57	197
rs:XP_011550483	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Plutella xylostella].	42.80	264	144	3	33	293	43	302	2e-57	208
rs:XP_007628811	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X6 [Cricetulus griseus].	41.28	298	126	3	3	294	113	367	2e-57	200
tr:A0A098BM29_9NOCA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.55	291	162	4	1	291	31	310	2e-57	198
rs:WP_003831856	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium breve].	39.86	291	166	5	6	292	5	290	2e-57	197
rs:WP_004760970	FolD protein [Acinetobacter sp. CIP 102129].	37.67	292	169	4	3	293	2	281	2e-57	197
rs:XP_002097109	GE26043 [Drosophila yakuba].	41.69	295	164	4	3	293	38	328	2e-57	208
rs:WP_004015524	5,10-methylene-tetrahydrofolate dehydrogenase [Mobiluncus mulieris].	37.37	297	177	6	2	294	8	299	2e-57	197
rs:WP_036289600	methenyltetrahydrofolate cyclohydrolase [Microbacterium sp. MRS-1].	39.00	300	168	8	1	293	1	292	2e-57	197
rs:XP_006758072	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Myotis davidii].	41.03	290	122	3	11	294	1	247	3e-57	196
rs:XP_009270061	C-1-tetrahydrofolate synthase, cytoplasmic [Wallemia ichthyophaga EXF-994].	40.54	296	164	4	1	292	1	288	3e-57	208
tr:A0A077MBH8_9MICO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.70	292	169	6	1	291	1	283	3e-57	197
tr:C6V5U3_NEORI	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:ACT69764.1};	50.72	209	90	4	83	289	1	198	3e-57	195
rs:WP_032874545	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter baumannii].	37.67	292	169	4	3	293	2	281	3e-57	197
rs:WP_042443934	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptacidiphilus jiangxiensis].	37.59	290	167	2	4	293	16	291	3e-57	197
rs:WP_019747654	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodococcus erythropolis].	39.93	293	165	4	1	293	4	285	3e-57	197
rs:WP_020096678	5,10-methylene-tetrahydrofolate dehydrogenase [Microbacterium sp. 11MF].	40.54	296	167	6	1	292	1	291	3e-57	197
rs:WP_003828919	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium breve].	39.86	291	166	5	6	292	5	290	3e-57	197
rs:XP_006738692	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Leptonychotes weddellii].	41.18	272	152	3	26	293	16	283	3e-57	204
rs:WP_005269749	FolD protein [Acinetobacter sp. NIPH 1859].	37.67	292	169	4	3	293	2	281	3e-57	197
tr:A0A091IGL1_CALAN	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFP06480.1}; Flags: Fragment;	41.55	284	157	4	15	293	2	281	3e-57	207
rs:WP_004021700	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia terrae].	39.24	288	165	5	6	293	9	286	3e-57	197
tr:K2EKW5_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.70	292	168	3	1	291	1	282	3e-57	197
rs:XP_009964905	PREDICTED: LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Tyto alba].	41.40	285	156	5	15	293	3	282	3e-57	207
rs:WP_005062925	FolD protein [Acinetobacter beijerinckii].	37.67	292	169	4	3	293	2	281	3e-57	197
tr:A0A087QQN1_APTFO	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFM03535.1}; Flags: Fragment;	42.11	285	154	5	15	293	2	281	3e-57	207
rs:XP_010310897	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Balearica regulorum gibbericeps].	42.11	285	154	5	15	293	2	281	3e-57	207
rs:WP_004893540	FolD 2 [Acinetobacter schindleri].	38.01	292	168	4	3	293	2	281	3e-57	197
tr:I3IAS3_9GAMM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.78	294	165	3	1	293	3	282	3e-57	197
rs:WP_033295192	methenyltetrahydrofolate cyclohydrolase [Amycolatopsis jejuensis].	39.79	284	160	4	1	284	1	273	3e-57	197
rs:WP_040391745	5,10-methylene-tetrahydrofolate cyclohydrolase [Cellvibrio sp. BR].	38.78	294	165	3	1	293	1	280	3e-57	197
rs:XP_005212054	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Bos taurus].	40.49	284	160	4	15	293	5	284	3e-57	207
rs:WP_035116907	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. NCR].	38.14	291	168	5	1	290	6	285	3e-57	197
rs:WP_026153778	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Amycolatopsis].	39.59	293	166	4	1	293	1	282	3e-57	197
rs:WP_020512559	5,10-methylene-tetrahydrofolate dehydrogenase [Actinoplanes globisporus].	36.77	291	175	3	2	292	9	290	3e-57	197
rs:WP_005048013	5,10-methylene-tetrahydrofolate dehydrogenase [Microbacterium laevaniformans].	38.33	300	170	8	1	293	1	292	3e-57	197
rs:WP_017574233	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis kunsanensis].	39.73	292	165	4	1	292	1	281	3e-57	197
rs:WP_019064385	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces prunicolor].	37.46	291	168	2	3	293	4	280	3e-57	197
tr:A0A063BQ69_9HYPO	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:KDB12671.1};	40.00	290	160	4	2	288	117	395	3e-57	209
rs:WP_004017552	5,10-methylene-tetrahydrofolate dehydrogenase [Mobiluncus mulieris].	37.37	297	177	6	2	294	8	299	3e-57	197
rs:WP_016659952	FolD 2 [Acinetobacter indicus].	38.36	292	167	5	3	293	2	281	4e-57	197
rs:WP_004652016	MULTISPECIES: FolD protein [Acinetobacter].	37.67	292	169	4	3	293	2	281	4e-57	197
rs:WP_024331013	methenyltetrahydrofolate cyclohydrolase [Actinomyces neuii].	38.18	296	170	6	3	292	9	297	4e-57	197
rs:XP_002031731	GM23891 [Drosophila sechellia].	41.36	295	165	4	3	293	38	328	4e-57	208
rs:WP_042543851	methenyltetrahydrofolate cyclohydrolase [Leucobacter komagatae].	40.60	298	166	6	1	293	1	292	4e-57	197
rs:WP_005144837	FolD protein [Acinetobacter sp. ANC 3929].	37.67	292	169	4	3	293	2	281	4e-57	197
tr:H3F1D0_PRIPA	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:PPA15901};	45.56	270	134	5	33	294	33	297	4e-57	205
tr:I1WYH4_DROME	SubName: Full=RH19138p1 {ECO:0000313|EMBL:AFI71924.1}; Flags: Fragment;	41.36	295	165	4	3	293	28	318	4e-57	207
tr:D9VQE2_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.25	285	162	2	2	286	8	278	4e-57	197
rs:WP_003790333	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces odontolyticus].	38.18	296	169	6	3	292	9	296	4e-57	197
rs:WP_035906904	methenyltetrahydrofolate cyclohydrolase [Knoellia subterranea].	37.67	292	174	4	1	292	1	284	4e-57	197
rs:WP_006593265	5,10-methylene-tetrahydrofolate dehydrogenase [Kineosphaera limosa].	37.46	291	169	5	1	291	1	278	4e-57	197
tr:A0A0B1PRF8_9BILA	SubName: Full=Formate--tetrahydrofolate ligase {ECO:0000313|EMBL:KHJ42802.1};	41.89	296	159	5	3	293	10	297	4e-57	207
rs:WP_006440697	methenyltetrahydrofolate cyclohydrolase [[Clostridium] hiranonis].	39.93	293	164	5	1	292	1	282	4e-57	197
sp:C1TC_SPOFR	RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3;	42.20	282	153	4	15	293	19	293	4e-57	207
rs:XP_011330628	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like isoform X3 [Cerapachys biroi].	41.36	295	166	3	3	292	36	328	4e-57	199
rs:WP_004694349	FolD 2 [Acinetobacter johnsonii].	37.33	292	170	4	3	293	2	281	4e-57	196
rs:WP_004663376	MULTISPECIES: FolD protein [Acinetobacter].	37.67	292	169	4	3	293	2	281	4e-57	196
rs:WP_015442915	methylenetetrahydrofolate dehydrogenase [Ilumatobacter coccineus].	40.89	291	158	5	1	290	1	278	4e-57	196
rs:WP_013669800	tetrahydrofolate dehydrogenase [Aerococcus urinae].	37.93	290	169	4	4	293	2	280	4e-57	196
rs:WP_025162301	methenyltetrahydrofolate cyclohydrolase [[Clostridium] bifermentans].	38.14	291	168	5	1	290	6	285	4e-57	197
sp:C1TC_DROME	RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3;	41.36	295	165	4	3	293	38	328	4e-57	207
tr:A0A085MMT7_9BILA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFD58533.1};	41.89	296	159	5	3	293	10	297	4e-57	207
rs:WP_040353715	methenyltetrahydrofolate cyclohydrolase [Corynebacterium caspium].	39.64	280	157	5	12	291	16	283	4e-57	197
rs:WP_038295706	methenyltetrahydrofolate cyclohydrolase [actinobacterium acMicro-1].	40.00	265	147	5	34	292	33	291	4e-57	197
tr:Q3UZH3_MOUSE	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:BAE21884.1}; Flags: Fragment;	44.36	257	135	3	41	293	45	297	4e-57	207
rs:WP_044495939	methenyltetrahydrofolate cyclohydrolase [Nesterenkonia sp. NP1].	38.80	299	170	6	1	293	1	292	5e-57	197
rs:WP_040419339	methenyltetrahydrofolate cyclohydrolase [Clostridium celatum].	37.72	289	169	2	3	291	2	279	5e-57	196
tr:A7A668_BIFAD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.38	292	168	5	6	293	54	340	5e-57	198
rs:WP_029239886	methenyltetrahydrofolate cyclohydrolase [Pseudonocardia sp. P1].	41.84	294	156	7	1	292	1	281	5e-57	196
rs:XP_006535240	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Mus musculus].	41.28	298	126	3	3	294	70	324	5e-57	197
gp:BT021278_1	RE42943p [Drosophila melanogaster]	41.36	295	165	4	3	293	4	294	5e-57	207
rs:XP_010125068	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Chlamydotis macqueenii].	41.20	284	158	4	15	293	2	281	5e-57	207
rs:NP_001247028	pugilist, isoform E [Drosophila melanogaster].	41.36	295	165	4	3	293	35	325	5e-57	207
rs:WP_005197928	FolD protein [Acinetobacter sp. NIPH 298].	37.67	292	169	4	3	293	2	281	5e-57	196
rs:WP_016651633	FolD protein [Acinetobacter sp. NIPH 2036].	37.67	292	169	4	3	293	2	281	5e-57	196
rs:XP_009460492	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Nipponia nippon].	41.75	285	155	5	15	293	94	373	5e-57	208
rs:WP_033134290	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter sp. MN12].	37.67	292	169	4	3	293	2	281	5e-57	196
rs:NP_477254	pugilist, isoform A [Drosophila melanogaster].	41.36	295	165	4	3	293	4	294	5e-57	207
rs:WP_016460204	FolD protein [Actinomyces sp. HPA0247].	38.18	296	169	6	3	292	9	296	5e-57	197
sp:FOLD2_RHOJR	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.55	291	162	4	1	291	1	280	5e-57	196
rs:WP_021954604	bifunctional protein FolD [Clostridium sp. CAG:921].	40.00	280	156	3	5	284	2	269	5e-57	196
rs:WP_021798798	tetrahydrofolate dehydrogenase [Propionibacterium acidifaciens].	41.78	292	157	5	1	291	1	280	5e-57	196
tr:A0A093P9Z6_PYGAD	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFW73236.1}; Flags: Fragment;	42.11	285	154	5	15	293	2	281	5e-57	207
rs:WP_004670310	FolD protein [Acinetobacter sp. CIP-A165].	37.67	292	169	4	3	293	2	281	5e-57	196
rs:WP_042152571	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NBRC 110027].	38.10	294	168	2	3	296	5	284	5e-57	196
rs:WP_027936413	methenyltetrahydrofolate cyclohydrolase [Amycolatopsis sp. ATCC 39116].	39.93	293	165	4	1	293	1	282	5e-57	196
tr:A0A0A9YFC8_LYGHE	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:JAG31767.1};	43.05	295	157	5	5	290	34	326	5e-57	198
rs:WP_024497192	methenyltetrahydrofolate cyclohydrolase [Gordonia amicalis].	39.86	281	158	4	6	286	9	278	5e-57	197
rs:WP_033219884	5,10-methylene-tetrahydrofolate cyclohydrolase [Kitasatospora phosalacinea].	37.59	290	167	2	6	295	1	276	5e-57	196
rs:XP_008265975	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Oryctolagus cuniculus].	38.93	298	133	3	3	294	42	296	5e-57	197
tr:L2TVQ8_9NOCA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.89	291	161	4	1	291	1	280	5e-57	196
rs:WP_004980984	FolD 2 [Acinetobacter johnsonii].	37.33	292	170	4	3	293	2	281	5e-57	196
rs:WP_041452240	methenyltetrahydrofolate cyclohydrolase [Amycolicicoccus subflavus].	40.07	292	164	4	1	292	4	284	6e-57	197
tr:A0A024Z1G3_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.46	286	162	2	4	289	17	288	6e-57	197
rs:WP_013406291	methylenetetrahydrofolate dehydrogenase [Halanaerobium hydrogeniformans].	37.89	285	162	4	6	290	4	273	6e-57	196
tr:A0A091JK96_9AVES	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFP20982.1}; Flags: Fragment;	42.11	285	154	5	15	293	2	281	6e-57	207
rs:WP_024541269	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium choerinum].	38.78	294	170	5	3	292	2	289	6e-57	196
rs:WP_033203591	methenyltetrahydrofolate cyclohydrolase [Gordonia terrae].	39.24	288	165	5	6	293	9	286	6e-57	196
rs:WP_009170405	tetrahydrofolate dehydrogenase [Clostridium sp. DL-VIII].	37.72	289	169	2	3	291	2	279	6e-57	196
rs:WP_005208138	FolD protein [Acinetobacter sp. NIPH 1867].	37.67	292	169	4	3	293	2	281	6e-57	196
rs:WP_004722464	FolD protein [Acinetobacter guillouiae].	37.67	292	169	4	3	293	2	281	6e-57	196
rs:WP_028556120	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus sp. URHA0014].	38.57	293	163	4	1	291	1	278	6e-57	196
gpu:CP011477_2228	5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase [Spongiibacter sp. IMCC21906]	36.39	294	172	3	1	293	44	323	6e-57	197
rs:WP_027263899	methenyltetrahydrofolate cyclohydrolase [Sedimentitalea nanhaiensis].	39.01	282	163	4	15	293	16	291	6e-57	197
tr:W6JY54_9MICO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.23	293	171	6	1	292	1	284	6e-57	196
rs:WP_016463456	FolD protein [Microbacterium sp. oral taxon 186].	38.33	300	170	8	1	293	1	292	6e-57	196
rs:WP_033515522	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium cuniculi].	40.96	293	164	6	3	291	2	289	6e-57	196
rs:XP_008137443	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Eptesicus fuscus].	40.85	284	159	4	15	293	35	314	7e-57	207
rs:WP_026935869	methenyltetrahydrofolate cyclohydrolase [Gulosibacter molinativorax].	41.92	291	160	6	6	292	12	297	7e-57	196
rs:WP_004819653	MULTISPECIES: FolD protein [Acinetobacter].	37.67	292	169	4	3	293	2	281	7e-57	196
rs:WP_032066437	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Acinetobacter baumannii].	39.71	272	151	4	23	293	1	260	7e-57	195
rs:WP_046456262	methenyltetrahydrofolate cyclohydrolase [Leucobacter sp. Ag1].	40.34	290	164	5	1	286	1	285	7e-57	196
rs:XP_005241888	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic, partial [Falco peregrinus].	41.05	285	157	5	15	293	5	284	7e-57	207
rs:WP_014179542	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces bingchenggensis].	36.99	292	170	2	2	293	6	283	7e-57	196
rs:WP_018569973	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. PsTaAH-124].	37.80	291	167	2	3	293	4	280	7e-57	196
rs:XP_005437356	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic, partial [Falco cherrug].	41.05	285	157	5	15	293	5	284	7e-57	207
rs:WP_034466062	methenyltetrahydrofolate cyclohydrolase [Actinomyces sp. ICM54].	38.18	296	169	6	3	292	9	296	7e-57	196
rs:WP_042216243	methenyltetrahydrofolate cyclohydrolase [Lysinimicrobium mangrovi].	41.16	294	164	6	4	293	10	298	7e-57	196
tr:W8HAN7_RHOOP	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.89	291	161	4	1	291	1	280	7e-57	196
rs:WP_020492287	methenyltetrahydrofolate cyclohydrolase [Dehalobacter sp. FTH1].	37.80	291	169	4	3	292	2	281	7e-57	196
rs:WP_018188842	5,10-methylene-tetrahydrofolate dehydrogenase [Microbacterium paraoxydans].	40.20	296	168	6	1	292	1	291	8e-57	196
rs:WP_014094760	methylenetetrahydrofolate dehydrogenase [Candidatus Arthromitus sp. SFB-rat-Yit].	40.32	253	140	2	36	288	35	276	8e-57	196
rs:XP_009331021	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Pygoscelis adeliae].	42.11	285	154	5	15	293	81	360	8e-57	207
rs:XP_007908447	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Callorhinchus milii].	40.13	299	168	5	1	293	1	294	8e-57	206
tr:W1JN12_9BRAD	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EJZ30562.1};	47.09	206	102	2	86	291	1	199	8e-57	194
rs:WP_037917898	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. PCS3-D2].	38.73	284	160	2	6	289	1	270	8e-57	196
rs:WP_038341957	5,10-methylene-tetrahydrofolate cyclohydrolase [Acinetobacter sp. A47].	37.67	292	169	4	3	293	2	281	8e-57	196
tr:M3AA57_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.15	259	149	2	31	289	39	291	8e-57	200
rs:WP_046644418	methenyltetrahydrofolate cyclohydrolase [Turicella otitidis].	39.38	292	166	4	2	293	9	289	8e-57	196
tr:Q4RLM3_TETNG	SubName: Full=Chromosome 10 SCAF15019, whole genome shotgun sequence {ECO:0000313|EMBL:CAG10709.1}; Flags: Fragment;	44.53	265	139	3	33	293	9	269	9e-57	206
rs:XP_007184340	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Balaenoptera acutorostrata scammoni].	40.85	284	159	4	15	293	26	305	9e-57	206
tr:X5S8U9_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.09	275	153	4	19	292	4	270	9e-57	196
tr:A0A087B474_9BIFI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.96	293	164	6	3	291	14	301	9e-57	196
rs:XP_007997077	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X4 [Chlorocebus sabaeus].	40.27	298	129	3	3	294	51	305	9e-57	196
tr:W1EFR2_KLEPN	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:CDL20925.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CDL20925.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CDL20925.1};	51.23	203	95	1	1	203	1	199	9e-57	194
tr:A0A091GCA1_9AVES	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFO78764.1}; Flags: Fragment;	41.52	289	158	5	11	293	1	284	9e-57	206
tr:A0A093HQA4_STRCA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFV81670.1}; Flags: Fragment;	40.70	285	158	5	15	293	5	284	9e-57	206
rs:WP_011166926	methenyltetrahydrofolate cyclohydrolase, partial [Mycoplasma mycoides].	45.79	214	107	3	73	286	8	212	9e-57	194
rs:WP_004805890	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces neuii].	37.84	296	171	6	3	292	9	297	9e-57	196
rs:WP_017610608	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis xinjiangensis].	39.73	292	165	4	1	292	1	281	1e-56	196
tr:I0WW36_9NOCA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.89	291	161	5	1	291	1	280	1e-56	196
rs:WP_030825557	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces].	38.03	284	162	2	6	289	1	270	1e-56	196
rs:WP_022871975	5,10-methylene-tetrahydrofolate dehydrogenase [Nesterenkonia alba].	39.39	297	167	6	1	291	1	290	1e-56	196
rs:WP_006434489	bifunctional protein FolD [Gordonia amicalis].	39.86	281	158	4	6	286	9	278	1e-56	196
rs:WP_045223968	methenyltetrahydrofolate cyclohydrolase, partial [Methylococcaceae bacterium 73a].	39.65	285	160	3	1	285	1	273	1e-56	195
tr:B4V2D5_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.19	288	164	2	2	289	8	281	1e-56	196
rs:XP_012153625	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X3 [Megachile rotundata].	44.63	242	127	3	54	292	2	239	1e-56	206
rs:WP_003947131	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	38.36	292	166	2	2	293	6	283	1e-56	196
rs:WP_017194836	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces massiliensis].	39.25	293	169	6	3	291	9	296	1e-56	196
rs:WP_019288557	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Rhodococcus].	40.56	286	159	4	1	286	4	278	1e-56	196
tr:A0A091WNP9_OPIHO	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFR17234.1}; Flags: Fragment;	41.75	285	155	5	15	293	2	281	1e-56	206
rs:WP_043276728	methenyltetrahydrofolate cyclohydrolase [Pseudonocardia sp. P2].	39.25	293	167	4	1	293	1	282	1e-56	196
rs:WP_023680453	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. LSJC280B00].	39.37	287	167	3	6	292	10	289	1e-56	196
rs:XP_005399188	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Chinchilla lanigera].	42.64	265	144	3	33	293	9	269	1e-56	206
rs:WP_045323395	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-4428].	38.03	284	162	2	6	289	1	270	1e-56	195
rs:WP_040491739	5,10-methylene-tetrahydrofolate cyclohydrolase [Ilumatobacter nonamiensis].	43.31	254	135	3	36	289	33	277	1e-56	196
tr:A0A091T5M2_NESNO	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFQ52753.1}; Flags: Fragment;	41.40	285	156	5	15	293	2	281	1e-56	206
rs:WP_030031453	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces flavotricini].	38.03	284	162	2	6	289	1	270	1e-56	195
rs:XP_010016298	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Nestor notabilis].	41.40	285	156	5	15	293	2	281	1e-56	206
rs:WP_045275848	methenyltetrahydrofolate cyclohydrolase [Microbacterium ketosireducens].	40.54	296	165	8	1	291	1	290	1e-56	196
rs:WP_009612075	5,10-methylene-tetrahydrofolate dehydrogenase [actinobacterium SCGC AAA027-L06].	40.21	286	157	4	1	286	1	272	1e-56	195
rs:WP_034268471	methenyltetrahydrofolate cyclohydrolase [Actinospica robiniae].	39.04	292	167	4	1	292	1	281	1e-56	195
rs:WP_016692848	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodococcus rhodochrous].	40.21	291	163	4	1	291	4	283	1e-56	195
rs:XP_005623549	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Canis lupus familiaris].	42.05	264	145	3	34	293	10	269	1e-56	206
tr:G3UV08_MELGA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMGAP00000019671}; Flags: Fragment;	40.40	297	166	5	4	293	5	297	1e-56	206
rs:WP_037676609	methenyltetrahydrofolate cyclohydrolase [Streptomyces griseus].	39.66	290	164	4	2	291	3	281	1e-56	195
tr:A0A085N9E7_9BILA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFD66093.1};	41.89	296	159	5	3	293	10	297	1e-56	206
rs:WP_023052577	tetrahydrofolate dehydrogenase [Megasphaera sp. BV3C16-1].	42.05	283	152	3	4	286	2	272	1e-56	195
rs:WP_017613690	5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis salina].	40.21	291	163	5	1	291	1	280	1e-56	195
rs:WP_005046044	5,10-methylene-tetrahydrofolate dehydrogenase [Halococcus salifodinae].	38.62	290	176	2	2	291	3	290	1e-56	196
tr:A0A0A0AXH4_CHAVO	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KGL98203.1}; Flags: Fragment;	41.40	285	156	5	15	293	2	281	1e-56	206
tr:E4YKK6_OIKDI	SubName: Full=Whole genome shotgun assembly, allelic scaffold set, scaffold scaffoldA_436 {ECO:0000313|EMBL:CBY36017.1};	41.32	288	160	5	6	289	5	287	2e-56	205
rs:WP_008414739	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces].	38.36	292	166	2	2	293	6	283	2e-56	195
rs:XP_010601308	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Fukomys damarensis].	43.02	265	143	3	33	293	9	269	2e-56	206
rs:XP_009673894	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Struthio camelus australis].	40.70	285	158	5	15	293	15	294	2e-56	206
rs:WP_019618959	hypothetical protein [Pseudoclavibacter faecalis].	39.60	298	167	6	1	292	1	291	2e-56	195
rs:WP_034497114	methenyltetrahydrofolate cyclohydrolase [Actinomyces sp. ICM39].	37.84	296	170	6	3	292	9	296	2e-56	196
rs:WP_014986234	methenyltetrahydrofolate cyclohydrolase [Nocardia brasiliensis].	42.47	259	139	2	34	292	33	281	2e-56	195
rs:WP_039197848	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium kashiwanohense].	39.04	292	169	5	6	293	5	291	2e-56	195
rs:WP_026502514	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium boum].	39.38	292	168	5	5	292	4	290	2e-56	195
rs:WP_037890302	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. Tu 6176].	37.80	291	167	2	3	293	4	280	2e-56	195
rs:XP_009875638	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Apaloderma vittatum].	40.00	295	168	4	4	293	32	322	2e-56	206
rs:WP_021873393	bifunctional protein FolD [Firmicutes bacterium CAG:822].	38.70	292	165	4	1	292	2	279	2e-56	196
tr:K2FWG9_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.40	285	150	6	5	288	2	270	2e-56	195
rs:WP_044504453	5,10-methylene-tetrahydrofolate cyclohydrolase [Megasphaera sp. NP3].	36.68	289	172	2	4	292	2	279	2e-56	195
rs:WP_005055198	FolD protein [Acinetobacter beijerinckii].	37.67	292	169	4	3	293	2	281	2e-56	195
tr:A0A076MPW1_AMYME	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.25	293	167	4	1	293	4	285	2e-56	195
rs:XP_012429732	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Taeniopygia guttata].	43.18	264	142	3	34	293	10	269	2e-56	205
rs:WP_017549360	hypothetical protein [Salinicoccus carnicancri].	38.44	294	167	6	5	296	4	285	2e-56	195
rs:WP_021284829	hypothetical protein [Clostridium sp. BL8].	36.81	288	171	2	6	293	5	281	2e-56	195
tr:K2BII4_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.52	293	174	3	1	293	1	281	2e-56	195
rs:WP_045862970	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. WMMB 714].	38.18	296	173	5	1	296	1	286	2e-56	195
rs:WP_045743087	methenyltetrahydrofolate cyclohydrolase [Actinoplanes rectilineatus].	37.80	291	172	3	2	292	3	284	2e-56	195
tr:A0A091Q9S5_MERNU	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFQ21582.1}; Flags: Fragment;	53.81	197	84	3	104	294	1	196	2e-56	192
rs:WP_030847085	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-4474].	38.08	281	160	2	6	286	1	267	2e-56	195
tr:A0A093F150_TAUER	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFV20421.1}; Flags: Fragment;	41.40	285	156	5	15	293	2	281	2e-56	205
rs:WP_030884496	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces].	36.46	288	169	2	6	293	1	274	2e-56	194
rs:WP_018471412	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. LaPpAH-202].	38.36	292	166	2	2	293	6	283	2e-56	195
tr:A0A0C4ERQ5_PUCT1	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblFungi:PTTG_03475P0};	43.75	256	127	4	54	296	2	253	2e-56	205
tr:A0A087XSU3_POEFO	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPFOP00000008846};	44.75	257	134	3	41	293	5	257	3e-56	205
rs:WP_037271549	5,10-methylene-tetrahydrofolate cyclohydrolase [Rhodococcus rhodnii].	37.54	293	167	3	5	297	3	279	3e-56	194
rs:WP_034329558	methenyltetrahydrofolate cyclohydrolase [Aminobacter sp. J41].	38.74	253	149	2	39	291	32	278	3e-56	194
rs:WP_015942841	methenyltetrahydrofolate cyclohydrolase [Desulfitobacterium hafniense].	38.19	288	166	4	4	290	3	279	3e-56	194
tr:F8W7P9_HUMAN	SubName: Full=Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|Ensembl:ENSP00000352012}; Flags: Fragment;	43.48	253	136	3	11	257	1	252	3e-56	193
rs:XP_006957186	FTHFS-domain-containing protein [Wallemia sebi CBS 633.66].	40.54	296	164	4	1	292	1	288	3e-56	205
tr:W1E2N8_KLEPN	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:CDL16004.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CDL16004.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CDL16004.1};	51.50	200	93	1	1	200	1	196	3e-56	192
tr:W8S9W0_9RHOB	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	43.33	270	147	2	1	270	1	264	3e-56	194
tr:R7YCU8_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.91	293	169	5	1	293	1	283	3e-56	195
tr:A0A0E2P3E6_9RHIZ	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:ESY24785.1};	40.88	274	153	4	19	291	4	269	3e-56	194
tr:A0A075GRH1_9EURY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.97	256	136	4	38	292	1	247	3e-56	193
rs:WP_013843036	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfotomaculum ruminis].	37.37	281	164	3	4	284	3	271	3e-56	194
rs:WP_028706446	methenyltetrahydrofolate cyclohydrolase [Propionibacterium acidifaciens].	41.44	292	158	5	1	291	1	280	3e-56	194
rs:WP_013805776	5,10-methylene-tetrahydrofolate dehydrogenase [Amycolicicoccus subflavus].	37.98	287	167	4	6	292	7	282	3e-56	195
rs:WP_003795426	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces odontolyticus].	37.84	296	170	6	3	292	9	296	3e-56	195
rs:WP_033514089	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium pullorum].	39.25	293	165	6	6	292	5	290	3e-56	194
rs:WP_021612216	tetrahydrofolate dehydrogenase [Actinomyces sp. oral taxon 172].	37.37	297	172	6	2	292	8	296	3e-56	195
rs:WP_046779977	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. fd2-tb].	38.03	284	162	2	6	289	1	270	3e-56	194
rs:WP_033266059	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces lydicus].	37.76	286	164	2	6	291	1	272	3e-56	194
rs:WP_044279958	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium thermophilum].	39.38	292	168	5	5	292	4	290	3e-56	194
sp:FOLD1_DESHY	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.85	288	167	4	4	290	3	279	3e-56	194
rs:WP_044570607	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. A3].	41.02	295	164	6	1	291	1	289	3e-56	194
rs:WP_046790731	hypothetical protein [Salinicoccus halodurans].	38.78	294	166	6	5	296	4	285	3e-56	194
rs:XP_011971144	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Ovis aries musimon].	42.05	264	145	3	34	293	10	269	3e-56	204
tr:K7F686_PELSI	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPSIP00000003546};	43.17	271	145	4	27	293	4	269	4e-56	204
tr:A0A0B2WRW1_9HYPO	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:KHN96374.1};	36.97	330	162	5	1	288	1	326	4e-56	205
tr:U3IU85_ANAPL	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAPLP00000010808}; Flags: Fragment;	41.81	287	155	5	15	293	14	296	4e-56	205
rs:WP_009479444	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodococcus sp. JVH1].	40.21	291	163	4	1	291	4	283	4e-56	194
rs:XP_010324900	PREDICTED: bifunctional protein FolD 4, chloroplastic-like isoform X7 [Solanum lycopersicum].	40.14	294	145	3	2	293	66	330	4e-56	196
rs:XP_009889512	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Charadrius vociferus].	41.40	285	156	5	15	293	84	363	4e-56	205
rs:WP_041812192	methenyltetrahydrofolate cyclohydrolase [Rhodococcus jostii].	40.21	291	163	4	1	291	4	283	4e-56	194
rs:WP_018679698	5,10-methylene-tetrahydrofolate dehydrogenase [Acinetobacter tjernbergiae].	37.33	292	170	4	3	293	2	281	4e-56	194
rs:WP_030234937	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces lavendulae].	37.54	285	164	2	2	286	5	275	4e-56	194
rs:WP_034880807	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium pseudocatenulatum].	39.04	292	169	5	6	293	5	291	4e-56	194
rs:WP_025133349	methenyltetrahydrofolate cyclohydrolase [Leucobacter sp. PH1c].	39.46	294	169	5	3	292	7	295	4e-56	194
rs:WP_033231290	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Rhodococcus].	40.56	286	159	4	1	286	4	278	4e-56	194
rs:WP_009213328	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces sp. oral taxon 180].	38.18	296	169	6	3	292	9	296	4e-56	194
rs:WP_030788817	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5008].	35.62	292	174	2	2	293	5	282	4e-56	194
rs:WP_037203726	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Rhodococcus].	40.55	291	162	4	1	291	4	283	4e-56	194
rs:WP_044927027	hypothetical protein, partial [Clostridiales bacterium VE202-21].	44.35	230	122	3	4	232	3	227	4e-56	192
rs:WP_029899079	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia brasiliensis].	42.47	259	139	2	34	292	33	281	4e-56	194
rs:WP_040309630	methenyltetrahydrofolate cyclohydrolase, partial [Asticcacaulis biprosthecium].	43.15	241	129	2	3	239	6	242	4e-56	192
rs:WP_037244880	methenyltetrahydrofolate cyclohydrolase [Rhodococcus wratislaviensis].	40.55	291	162	4	1	291	4	283	4e-56	194
rs:WP_006359168	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia alkanivorans].	39.15	281	160	4	6	286	9	278	5e-56	194
rs:WP_030763600	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-2664].	37.72	281	161	2	6	286	1	267	5e-56	194
rs:WP_004221587	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium].	39.04	292	169	5	6	293	5	291	5e-56	194
rs:WP_009152482	5,10-methylene-tetrahydrofolate dehydrogenase [Saccharomonospora marina].	39.08	284	162	4	1	284	1	273	5e-56	194
tr:J2ZAK1_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.88	293	168	6	6	292	1	285	5e-56	194
rs:WP_022433517	bifunctional protein FolD [Mycoplasma sp. CAG:472].	38.73	284	159	3	5	288	2	270	5e-56	194
tr:E4YGW3_OIKDI	SubName: Full=Whole genome shotgun assembly, allelic scaffold set, scaffold scaffoldA_265 {ECO:0000313|EMBL:CBY34737.1};	40.97	288	161	5	6	289	5	287	5e-56	204
tr:A0A094PIH2_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:KGA11420.1};	41.82	275	150	4	16	289	17	282	5e-56	194
rs:WP_014553713	methylenetetrahydrofolate dehydrogenase [Halanaerobium praevalens].	37.76	286	163	4	6	291	4	274	5e-56	194
rs:XP_011862167	PREDICTED: uncharacterized protein LOC105558856 [Vollenhovia emeryi].	50.23	213	95	3	78	289	283	485	5e-56	199
rs:WP_045951951	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces katrae].	38.03	284	162	2	6	289	1	270	5e-56	194
rs:WP_007628189	5,10-methylene-tetrahydrofolate dehydrogenase [Dietzia cinnamea].	42.16	287	153	6	1	286	1	275	5e-56	194
rs:WP_037688960	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces atratus].	37.32	284	164	2	6	289	1	270	5e-56	194
rs:WP_013795145	5,10-methylene-tetrahydrofolate dehydrogenase [Marinomonas posidonica].	36.18	293	173	2	1	293	1	279	5e-56	194
sp:FOLD_CARHZ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	41.18	289	160	4	3	290	2	281	5e-56	194
rs:WP_047311815	methenyltetrahydrofolate cyclohydrolase [Dermacoccus sp. PE3].	40.21	291	161	5	1	291	1	278	6e-56	194
rs:WP_003840571	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium].	38.62	290	169	5	6	291	5	289	6e-56	194
rs:WP_019224855	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Dehalobacter].	38.06	289	167	4	4	291	3	280	6e-56	194
rs:WP_015042306	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Dehalobacter].	38.41	289	166	4	4	291	3	280	6e-56	194
rs:WP_026060571	methenyltetrahydrofolate cyclohydrolase [Pseudaminobacter salicylatoxidans].	38.33	287	170	3	6	292	9	288	6e-56	194
rs:WP_012867764	5,10-methylene-tetrahydrofolate dehydrogenase [Sanguibacter keddieii].	40.74	297	167	6	1	293	1	292	6e-56	194
rs:WP_028052051	methenyltetrahydrofolate cyclohydrolase [Carboxydothermus ferrireducens].	40.83	289	161	4	3	290	2	281	6e-56	194
rs:WP_018226475	5,10-methylene-tetrahydrofolate dehydrogenase [actinobacterium SCGC AAA028-A23].	40.21	286	157	4	1	286	1	272	6e-56	193
rs:WP_047224587	5,10-methylene-tetrahydrofolate cyclohydrolase [Frankia sp. BMG5.1].	39.58	288	160	5	4	291	2	275	6e-56	193
rs:WP_037179111	methenyltetrahydrofolate cyclohydrolase [Rhodococcus opacus].	40.55	291	162	4	1	291	4	283	6e-56	194
tr:E4XT81_OIKDI	SubName: Full=Whole genome shotgun assembly, reference scaffold set, scaffold scaffold_135 {ECO:0000313|EMBL:CBY12943.1};	40.97	288	161	5	6	289	5	287	6e-56	204
tr:T0DLA5_9DELT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.88	293	166	6	4	291	6	287	6e-56	194
rs:XP_008991430	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X4 [Callithrix jacchus].	39.93	298	130	3	3	294	51	305	6e-56	194
rs:WP_038114325	5,10-methylene-tetrahydrofolate cyclohydrolase [Veillonella sp. AS16].	37.68	276	158	3	8	283	6	267	6e-56	193
tr:A0A0D6CXN1_9BIFI	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:BAR03433.1};	39.04	292	169	5	6	293	8	294	6e-56	194
tr:D3ZZM8_RAT	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSRNOP00000023913};	40.68	295	164	5	3	290	4	294	7e-56	204
rs:WP_026961200	5,10-methylene-tetrahydrofolate cyclohydrolase [Alicyclobacillus herbarius].	37.85	288	164	3	5	292	6	278	7e-56	193
rs:WP_014966451	5,10-methylene-tetrahydrofolate dehydrogenase [Gottschalkia acidurici].	37.37	281	166	2	6	286	4	274	7e-56	193
rs:XP_008773732	PREDICTED: LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic-like [Rattus norvegicus].	40.68	295	164	5	3	290	4	294	7e-56	204
rs:WP_025046457	methenyltetrahydrofolate cyclohydrolase [Sulfitobacter mediterraneus].	36.86	293	173	3	1	293	1	281	7e-56	194
rs:XP_005285948	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Chrysemys picta bellii].	43.18	264	142	3	34	293	10	269	7e-56	204
rs:WP_006900024	bifunctional protein FolD [Gordonia paraffinivorans].	39.24	288	164	5	6	293	9	285	7e-56	194
tr:A0A074JB77_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	41.86	258	136	2	34	291	25	268	7e-56	193
rs:XP_012037208	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Ovis aries].	42.05	264	145	3	34	293	10	269	7e-56	204
tr:A0A091DMS6_FUKDA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFO24101.1};	43.13	262	141	3	36	293	38	295	7e-56	204
rs:WP_037778144	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. AW19M42].	36.81	288	168	2	6	293	1	274	7e-56	193
rs:WP_006865968	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia namibiensis].	39.50	281	159	4	6	286	9	278	7e-56	194
rs:WP_031546581	hypothetical protein [Salinicoccus luteus].	38.91	293	167	5	5	296	4	285	7e-56	194
gp:CP003421_445	Bifunctional protein folD [Corynebacterium pseudotuberculosis 31]	45.57	237	119	3	54	290	2	228	7e-56	192
rs:WP_030962867	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-378].	37.72	281	161	2	6	286	1	267	7e-56	193
tr:D8LU87_ECTSI	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CBN75428.1};	40.93	259	147	3	27	284	2	255	7e-56	199
rs:WP_022746807	bifunctional protein FolD [Clostridium saccharobutylicum].	37.67	292	171	2	3	294	2	282	7e-56	193
rs:WP_043450548	methenyltetrahydrofolate cyclohydrolase [Arthrobacter phenanthrenivorans].	40.40	297	164	6	2	292	6	295	8e-56	194
rs:WP_039950915	methenyltetrahydrofolate cyclohydrolase [Rhodococcus imtechensis].	40.55	291	162	5	1	291	4	283	8e-56	193
rs:WP_034526445	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium stellenboschense].	39.04	292	165	6	6	291	5	289	8e-56	194
rs:WP_016933206	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodococcus sp. R1101].	39.86	291	164	4	1	291	4	283	8e-56	193
tr:A0A014P1R0_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.55	290	170	2	2	291	6	281	8e-56	194
rs:WP_019174667	5,10-methylene-tetrahydrofolate dehydrogenase [Brevibacterium massiliense].	38.14	291	171	5	6	292	5	290	8e-56	194
rs:WP_037991546	5,10-methylene-tetrahydrofolate cyclohydrolase [Thalassospira permensis].	41.86	258	136	2	34	291	40	283	9e-56	193
rs:WP_046258176	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. WM6386].	36.77	291	170	2	3	293	4	280	9e-56	193
rs:WP_037895865	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces xanthophaeus].	37.19	285	165	2	2	286	5	275	9e-56	193
rs:WP_026867153	hypothetical protein [Jeotgalicoccus marinus].	39.80	294	163	6	5	296	4	285	9e-56	193
rs:WP_042260931	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia brasiliensis].	42.47	259	139	2	34	292	33	281	9e-56	193
rs:WP_042804298	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. C].	38.43	281	159	2	6	286	1	267	9e-56	193
rs:WP_030385253	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-241].	37.72	281	161	2	6	286	1	267	9e-56	193
rs:WP_030649633	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces].	37.72	281	161	2	6	286	1	267	9e-56	193
rs:WP_014245855	folD bifunctional protein [Bacteriovorax marinus].	40.89	291	155	5	10	293	10	290	9e-56	193
tr:A0A0B4EVQ1_9FUSO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KID49004.1};	52.13	188	80	3	97	284	1	178	9e-56	195
rs:WP_023955612	dehydrogenase [Microbacterium sp. TS-1].	38.85	296	172	6	1	292	1	291	1e-55	193
rs:XP_009364291	PREDICTED: bifunctional protein FolD 2-like isoform X2 [Pyrus x bretschneideri].	40.14	294	170	2	2	293	53	342	1e-55	195
rs:XP_006018753	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic, partial [Alligator sinensis].	40.49	284	160	4	15	293	3	282	1e-55	203
rs:WP_040314679	hypothetical protein [Bacteriovorax sp. BAL6_X].	38.93	280	155	6	17	291	6	274	1e-55	192
rs:WP_014926213	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia].	38.89	288	166	5	6	293	9	286	1e-55	193
rs:WP_003843904	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium dentium].	38.28	290	170	5	6	291	5	289	1e-55	193
tr:D3B0K8_POLPA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFA84832.1};	37.59	274	164	3	6	273	926	1198	1e-55	205
rs:WP_026643184	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium pseudolongum].	39.93	293	167	6	3	291	2	289	1e-55	193
rs:XP_005265747	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X4 [Homo sapiens].	43.48	253	136	3	11	257	1	252	1e-55	193
rs:XP_004766331	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Mustela putorius furo].	43.87	253	135	3	11	257	1	252	1e-55	194
rs:XP_009364290	PREDICTED: bifunctional protein FolD 2-like isoform X1 [Pyrus x bretschneideri].	40.14	294	170	2	2	293	54	343	1e-55	195
tr:G5BMF3_HETGA	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:EHB10464.1};	42.76	297	139	8	3	292	20	292	1e-55	193
rs:WP_022858592	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium pseudolongum].	39.93	293	167	6	3	291	2	289	1e-55	193
rs:WP_034252615	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium crudilactis].	39.18	291	168	5	6	292	5	290	1e-55	193
rs:WP_037571507	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptacidiphilus oryzae].	36.64	292	171	2	2	293	6	283	1e-55	193
rs:WP_046906060	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces showdoensis].	36.99	292	170	2	2	293	5	282	1e-55	193
rs:WP_039638485	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. 769].	39.04	292	164	2	2	293	8	285	1e-55	193
rs:WP_046120171	methenyltetrahydrofolate cyclohydrolase, partial [Sinorhizobium sp. PC2].	43.51	262	137	6	1	257	4	259	1e-55	192
rs:WP_030771639	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces griseus].	38.01	292	167	2	2	293	6	283	1e-55	193
tr:G1PUV4_MYOLU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMLUP00000015079}; Flags: Fragment;	41.20	284	154	5	15	293	4	279	1e-55	203
rs:XP_011909378	PREDICTED: LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic [Cercocebus atys].	43.35	263	140	4	35	293	265	522	1e-55	205
rs:WP_043447891	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces nodosus].	43.86	285	148	3	6	290	5	277	1e-55	193
rs:WP_031158015	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces erythrochromogenes].	37.72	281	161	2	6	286	1	267	2e-55	192
rs:WP_007540906	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Aquiluna sp. IMCC13023].	38.23	293	166	5	1	289	1	282	2e-55	192
rs:WP_030695516	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces griseus].	37.67	292	168	2	2	293	6	283	2e-55	192
rs:WP_037140498	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	39.93	293	165	4	1	293	4	285	2e-55	192
rs:XP_008570691	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Galeopterus variegatus].	42.19	256	141	3	11	260	1	255	2e-55	192
rs:WP_030212364	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces bikiniensis].	36.99	292	170	2	2	293	5	282	2e-55	192
rs:XP_011530282	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Homo sapiens].	40.60	298	128	3	3	294	154	408	2e-55	196
rs:WP_019983529	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. Amel2xE9].	36.43	291	171	2	3	293	4	280	2e-55	192
rs:WP_036390367	5,10-methylene-tetrahydrofolate cyclohydrolase [Mycobacterium farcinogenes].	42.56	289	151	4	1	289	1	274	2e-55	192
rs:WP_007061833	methenyltetrahydrofolate cyclohydrolase [Clostridium carboxidivorans].	39.45	289	163	5	3	290	2	279	2e-55	192
rs:XP_009238353	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Pongo abelii].	54.31	197	83	3	104	294	8	203	2e-55	190
rs:WP_009777871	5,10-methylene-tetrahydrofolate dehydrogenase [Janibacter sp. HTCC2649].	37.80	291	173	4	1	291	1	283	2e-55	193
rs:WP_013240367	methenyltetrahydrofolate cyclohydrolase [Clostridium ljungdahlii].	39.10	289	164	5	3	290	2	279	2e-55	192
rs:XP_004900118	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Heterocephalus glaber].	42.80	271	147	4	3	266	22	291	2e-55	192
tr:H2PDL4_PONAB	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000016565}; Flags: Fragment;	54.31	197	83	3	104	294	5	200	2e-55	190
tr:E0Q779_9BIFI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.49	291	168	6	6	291	21	305	2e-55	193
rs:WP_019667991	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Rhodococcus].	39.93	293	165	4	1	293	4	285	2e-55	192
rs:WP_015450401	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium thermophilum].	39.38	292	168	5	5	292	4	290	2e-55	192
rs:WP_024287101	methenyltetrahydrofolate cyclohydrolase [Cellulomonas sp. KRMCY2].	42.26	265	141	5	34	292	33	291	2e-55	193
rs:XP_008947410	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Merops nubicus].	53.81	197	84	3	104	294	58	253	2e-55	191
rs:WP_014697818	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium animalis].	38.57	293	171	5	3	291	2	289	2e-55	192
rs:WP_037052232	methenyltetrahydrofolate cyclohydrolase [Pseudonocardia autotrophica].	38.01	292	172	3	1	292	1	283	2e-55	192
rs:XP_009580319	PREDICTED: LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic-like [Fulmarus glacialis].	42.42	264	144	3	34	293	10	269	2e-55	202
rs:WP_013138803	5,10-methylene-tetrahydrofolate dehydrogenase [Segniliparus rotundus].	37.41	294	167	5	1	291	1	280	2e-55	192
rs:WP_033349309	methenyltetrahydrofolate cyclohydrolase [Leucobacter salsicius].	39.32	295	170	5	2	292	7	296	2e-55	193
rs:WP_033359921	methenyltetrahydrofolate cyclohydrolase [Dactylosporangium aurantiacum].	37.24	290	173	3	2	291	5	285	2e-55	192
rs:XP_007460123	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Lipotes vexillifer].	39.79	284	162	4	15	293	26	305	2e-55	203
rs:XP_008228847	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X2 [Prunus mume].	40.96	293	167	2	2	292	58	346	2e-55	194
tr:K7IEB9_CAEJA	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:CJA41145};	41.33	300	159	7	1	291	1	292	2e-55	193
rs:WP_023666074	methenyltetrahydrofolate cyclohydrolase [Rhodobacter sp. CACIA14H1].	36.55	290	172	3	1	290	1	278	2e-55	192
rs:WP_015889998	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodococcus opacus].	40.21	291	163	4	1	291	4	283	2e-55	192
sp:FOLD2_NOCSJ	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.04	292	167	4	1	292	1	281	2e-55	192
rs:WP_030429164	5,10-methylene-tetrahydrofolate cyclohydrolase [Allokutzneria albata].	38.03	284	162	2	6	289	1	270	2e-55	192
sp:FOLD1_NOCSJ	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.62	290	167	4	3	292	5	283	2e-55	192
rs:WP_042815974	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. RSD-27].	37.72	281	161	2	6	286	1	267	2e-55	192
rs:XP_010190522	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Mesitornis unicolor].	42.42	264	144	3	34	293	10	269	2e-55	202
rs:WP_015495788	methenyltetrahydrofolate cyclohydrolase [Octadecabacter arcticus].	37.63	279	167	2	15	293	18	289	2e-55	192
rs:WP_041887936	methenyltetrahydrofolate cyclohydrolase [actinobacterium acIB-AMD-6].	36.43	291	171	4	1	291	1	277	2e-55	192
rs:WP_028431071	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. TAA204].	38.36	292	170	5	1	292	1	282	3e-55	192
rs:XP_008228838	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X1 [Prunus mume].	40.96	293	167	2	2	292	62	350	3e-55	194
rs:WP_030012160	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces lavendulae].	37.72	281	161	2	6	286	1	267	3e-55	192
rs:XP_007184342	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X3 [Balaenoptera acutorostrata scammoni].	42.42	264	144	3	34	293	10	269	3e-55	202
rs:WP_009649216	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces sp. ICM47].	37.71	297	171	6	2	292	8	296	3e-55	192
rs:XP_010085838	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Pterocles gutturalis].	42.42	264	144	3	34	293	10	269	3e-55	202
tr:M7BIJ7_CHEMY	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:EMP28072.1}; Flags: Fragment;	43.19	257	138	3	41	293	1	253	3e-55	201
rs:WP_037111560	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	39.59	293	166	4	1	293	4	285	3e-55	192
rs:WP_016208656	5,10-methylene-tetrahydrofolate dehydrogenase [Clostridium sartagoforme].	35.52	290	176	2	3	292	2	280	3e-55	192
rs:WP_033520374	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium bohemicum].	39.32	295	170	5	3	293	2	291	3e-55	192
rs:XP_004900116	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Heterocephalus glaber].	43.35	263	142	3	3	259	22	283	3e-55	193
rs:WP_018896159	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. CNY228].	38.01	292	167	2	2	293	6	283	3e-55	192
tr:C1BVL5_LEPSM	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:ACO13068.1};	40.14	294	161	6	6	289	9	297	3e-55	192
rs:WP_036953046	methenyltetrahydrofolate cyclohydrolase, partial [Promicromonosporaceae bacterium W15].	40.94	276	154	5	15	286	3	273	3e-55	192
rs:XP_007908446	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Callorhinchus milii].	40.34	295	165	5	5	293	21	310	3e-55	202
rs:XP_006760169	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Myotis davidii].	43.58	257	137	3	41	293	173	425	3e-55	203
rs:WP_047000884	methenyltetrahydrofolate cyclohydrolase [Clostridium beijerinckii].	35.86	290	175	2	3	292	2	280	3e-55	192
tr:S2QW52_LACPA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	49.30	215	99	2	70	284	4	208	3e-55	189
rs:WP_042276949	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. 01].	39.31	290	164	5	2	290	7	285	4e-55	192
tr:X1U8Y3_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_S09106 {ECO:0000313|EMBL:GAI96330.1};	43.46	214	121	0	1	214	1	214	4e-55	190
rs:WP_009056122	5,10-methylene-tetrahydrofolate dehydrogenase [Atopobium sp. ICM58].	36.70	297	174	6	2	292	8	296	4e-55	192
rs:XP_009486612	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Pelecanus crispus].	41.98	262	144	3	34	291	10	267	4e-55	199
rs:WP_023591253	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces thermolilacinus].	36.86	293	169	3	3	293	7	285	4e-55	192
rs:WP_018761942	5,10-methylene-tetrahydrofolate dehydrogenase [Arthrobacter sp. 135MFCol5.1].	39.73	297	166	6	2	292	6	295	4e-55	192
rs:WP_015770987	5,10-methylene-tetrahydrofolate dehydrogenase [Jonesia denitrificans].	38.72	297	173	6	1	293	1	292	4e-55	192
tr:A0A0A8EVQ6_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.04	292	164	2	2	293	38	315	4e-55	192
rs:WP_023636673	methylenetetrahydrofolate dehydrogenase, partial [Shigella dysenteriae].	51.24	201	88	3	97	297	3	193	4e-55	188
tr:F0E5J0_PSEDT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	47.87	211	102	3	82	292	3	205	4e-55	189
rs:WP_008729595	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces massiliensis].	38.57	293	171	6	3	291	9	296	4e-55	192
rs:WP_037791200	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. Mg1].	38.03	284	162	2	6	289	1	270	5e-55	191
rs:WP_021647438	tetrahydrofolate dehydrogenase [Bifidobacterium bifidum].	39.38	292	168	5	6	293	5	291	5e-55	191
rs:WP_026406298	methenyltetrahydrofolate cyclohydrolase [Actinomyces gerencseriae].	38.57	293	171	6	3	291	9	296	5e-55	192
rs:XP_009338903	PREDICTED: bifunctional protein FolD 2-like isoform X2 [Pyrus x bretschneideri].	39.80	294	171	2	2	293	53	342	5e-55	193
tr:S4NT00_9NEOP	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:JAA78718.1};	39.93	283	162	4	15	293	15	293	5e-55	202
rs:WP_020836084	methylenetetrahydrofolate dehydrogenase [Spiroplasma diminutum].	39.58	283	158	3	4	286	3	272	5e-55	191
rs:WP_018163425	5,10-methylene-tetrahydrofolate dehydrogenase [Smaragdicoccus niigatensis].	40.00	295	160	5	1	292	1	281	5e-55	191
rs:WP_014146366	methenyltetrahydrofolate cyclohydrolase [Streptomyces cattleya].	38.62	290	167	4	2	291	3	281	5e-55	191
tr:I0KYT8_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.43	291	176	3	2	292	16	297	5e-55	192
rs:WP_033503316	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium actinocoloniiforme].	39.93	293	161	7	6	291	5	289	5e-55	192
rs:WP_005195909	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia rubripertincta].	39.15	281	160	4	6	286	9	278	5e-55	192
sp:FOLD1_STRAW	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.33	292	169	2	2	293	6	283	5e-55	191
rs:XP_009338902	PREDICTED: bifunctional protein FolD 2-like isoform X1 [Pyrus x bretschneideri].	39.80	294	171	2	2	293	54	343	5e-55	193
tr:L5M2Z1_MYODS	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:ELK32994.1};	43.92	255	135	3	41	291	75	325	6e-55	204
rs:WP_033238374	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces griseus].	38.01	292	167	2	2	293	6	283	6e-55	191
rs:WP_028653884	methenyltetrahydrofolate cyclohydrolase [Nocardioides sp. J54].	38.97	290	166	4	1	290	1	279	6e-55	191
rs:WP_026430044	methenyltetrahydrofolate cyclohydrolase [Actinomyces georgiae].	37.50	296	170	6	3	292	9	295	6e-55	191
rs:XP_001518406	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like, partial [Ornithorhynchus anatinus].	44.93	227	117	3	61	283	5	227	6e-55	189
rs:WP_044665734	5,10-methylene-tetrahydrofolate cyclohydrolase [Syntrophaceticus schinkii].	39.25	293	163	5	1	291	1	280	6e-55	191
rs:WP_047289016	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium bifidum].	39.04	292	169	5	6	293	5	291	7e-55	191
rs:WP_030868122	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-2747].	38.08	281	160	2	6	286	1	267	7e-55	191
rs:WP_003812718	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium bifidum].	39.04	292	169	5	6	293	5	291	7e-55	191
rs:WP_046515672	hypothetical protein [Salinicoccus sp. SV-16].	38.44	294	167	6	5	296	4	285	7e-55	191
rs:WP_023353418	tetrahydrofolate dehydrogenase [Catonella morbi].	36.71	286	170	4	4	288	2	277	7e-55	191
rs:WP_010144801	5,10-methylene-tetrahydrofolate dehydrogenase [Citricoccus sp. CH26A].	38.93	298	168	6	1	292	1	290	7e-55	191
rs:WP_041879596	hypothetical protein [Candidatus Xenolissoclinum pacificiensis].	38.97	290	155	6	5	289	3	275	7e-55	191
rs:WP_021719098	bifunctional protein FolD [Phascolarctobacterium sp. CAG:207].	40.78	282	154	5	1	282	1	269	7e-55	191
rs:WP_018000794	methenyltetrahydrofolate cyclohydrolase [Paracoccus sp. N5].	36.77	291	173	4	5	293	14	295	7e-55	191
rs:WP_008679122	tetrahydrofolate dehydrogenase [Clostridium sp. 7_2_43FAA].	36.55	290	173	2	3	292	2	280	7e-55	191
rs:WP_042184127	5,10-methylene-tetrahydrofolate cyclohydrolase [Kibdelosporangium sp. MJ126-NF4].	37.28	287	164	3	5	291	3	273	7e-55	191
rs:WP_033493122	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium thermophilum].	39.38	292	168	5	5	292	4	290	7e-55	191
rs:WP_006380305	tetrahydrofolate dehydrogenase [Streptomyces turgidiscabies].	36.43	291	171	2	3	293	4	280	7e-55	191
rs:XP_009512880	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Phalacrocorax carbo].	41.29	264	147	3	34	293	10	269	8e-55	197
rs:WP_013258148	5,10-methylene-tetrahydrofolate dehydrogenase [Desulfarculus baarsii].	38.62	290	165	5	1	288	1	279	8e-55	191
rs:XP_008539340	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Equus przewalskii].	38.97	290	128	3	11	294	1	247	8e-55	189
rs:WP_010636612	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. S4].	38.01	292	167	2	2	293	6	283	8e-55	191
rs:WP_043669155	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia vulneris].	41.70	259	141	2	34	292	33	281	8e-55	191
rs:WP_002843223	methenyltetrahydrofolate cyclohydrolase [Peptostreptococcus anaerobius].	39.86	291	163	5	4	293	21	300	8e-55	191
rs:WP_036536215	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Nocardia cyriacigeorgica].	42.57	249	133	2	44	292	4	242	8e-55	189
rs:WP_022173940	bifunctional protein FolD [Bifidobacterium bifidum CAG:234].	39.04	292	169	5	6	293	5	291	8e-55	191
rs:WP_038470923	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. PAMC25486].	39.86	296	168	6	1	292	1	290	8e-55	191
gp:AX882632_1	Sequence 17537 from Patent EP1074617. [Homo sapiens]	54.31	197	83	3	104	294	41	236	8e-55	189
rs:WP_007286366	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Clostridiales].	38.49	291	168	4	3	292	2	282	8e-55	191
rs:WP_015320693	5,10-methylene-tetrahydrofolate dehydrogenase [Natronococcus occultus].	38.57	293	172	3	1	293	1	285	8e-55	191
rs:WP_019148201	5,10-methylene-tetrahydrofolate dehydrogenase [Timonella senegalensis].	39.26	298	168	6	1	292	1	291	9e-55	191
rs:WP_033495395	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium psychraerophilum].	37.67	292	173	5	6	293	5	291	9e-55	191
rs:WP_009749048	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces sp. oral taxon 448].	37.20	293	175	6	2	290	8	295	9e-55	191
rs:XP_010084713	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Pterocles gutturalis].	50.00	202	94	3	102	297	1	201	9e-55	188
rs:WP_036647511	5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus pini].	38.91	293	162	5	1	291	1	278	1e-54	191
rs:WP_024620825	methenyltetrahydrofolate cyclohydrolase [[Clostridium] mangenotii].	38.06	289	167	5	3	290	8	285	1e-54	191
tr:A0A067MRA7_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDQ14131.1};	37.50	296	175	4	2	291	9	300	1e-54	201
rs:WP_015491119	5,10-methylene-tetrahydrofolate dehydrogenase [Clavibacter michiganensis].	38.98	295	171	6	1	291	1	290	1e-54	191
rs:XP_008499272	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Calypte anna].	42.26	265	145	3	33	293	9	269	1e-54	201
tr:A0A0B2VQD6_TOXCA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KHN83783.1};	45.15	299	146	8	3	291	2	292	1e-54	201
rs:WP_044092038	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium thermacidophilum].	39.38	292	168	5	5	292	4	290	1e-54	191
rs:WP_019977676	hypothetical protein, partial [alpha proteobacterium SCGC AAA300-J04].	43.51	239	131	1	1	239	1	235	1e-54	189
rs:WP_030598078	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces fulvoviolaceus].	41.03	290	159	3	6	295	5	282	1e-54	190
rs:WP_040796951	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia higoensis].	40.21	286	160	4	6	291	6	280	1e-54	190
rs:XP_008826699	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like, partial [Nannospalax galili].	39.36	282	160	5	15	290	27	303	1e-54	196
tr:A0A0A1D4Q3_9MICC	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.86	296	168	6	1	292	5	294	1e-54	191
rs:WP_009353460	5,10-methylene-tetrahydrofolate dehydrogenase [Veillonella sp. oral taxon 780].	37.91	277	160	3	8	284	6	270	1e-54	190
gp:CP010433_985	5, 10-methylene-tetrahydrofolatedehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Bifidobacterium animalis]	39.55	268	154	4	28	291	17	280	1e-54	190
rs:WP_034509371	methenyltetrahydrofolate cyclohydrolase [Actinomyces sp. S4-C9].	40.88	296	158	9	3	291	9	294	1e-54	191
rs:XP_009941168	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Opisthocomus hoazin].	42.42	264	144	3	34	293	10	269	1e-54	200
tr:F7DVH9_ORNAN	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOANP00000021739}; Flags: Fragment;	51.00	200	91	3	102	295	1	199	1e-54	188
rs:WP_035469153	methenyltetrahydrofolate cyclohydrolase [Alicyclobacillus acidocaldarius].	38.03	284	163	4	3	286	2	272	1e-54	190
rs:WP_019136459	5,10-methylene-tetrahydrofolate dehydrogenase [Cellulomonas massiliensis].	40.68	295	166	6	1	291	1	290	1e-54	190
rs:WP_030171157	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Actinomycetales].	40.27	298	162	6	1	293	1	287	1e-54	190
rs:WP_030292903	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces katrae].	37.59	282	162	2	5	286	13	280	1e-54	190
rs:WP_034931534	methenyltetrahydrofolate cyclohydrolase [Erysipelotrichaceae bacterium NK3D112].	37.46	291	171	4	3	292	2	282	2e-54	190
rs:WP_012864773	5,10-methylene-tetrahydrofolate dehydrogenase [Veillonella parvula].	38.13	278	158	3	6	283	4	267	2e-54	190
rs:WP_030729766	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces].	37.37	281	162	2	6	286	1	267	2e-54	190
rs:WP_033202757	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces wedmorensis].	36.99	292	170	2	2	293	5	282	2e-54	190
rs:WP_028852202	methenyltetrahydrofolate cyclohydrolase [Thermocrispum municipale].	40.85	284	157	4	1	284	1	273	2e-54	190
rs:WP_040194834	hypothetical protein [Clostridium sp. CL-6].	38.41	289	167	2	6	294	5	282	2e-54	190
rs:WP_033505429	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium thermacidophilum].	39.38	292	168	5	5	292	4	290	2e-54	190
rs:WP_043269160	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. CT34].	37.85	288	165	2	6	293	1	274	2e-54	190
rs:WP_003819778	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium bifidum].	38.70	292	170	5	6	293	5	291	2e-54	190
tr:F8TER8_9CLOT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.89	288	164	5	4	290	3	279	2e-54	190
rs:WP_017237301	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. SS].	36.99	292	170	2	2	293	5	282	2e-54	190
rs:WP_037957667	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. PRh5].	36.71	286	167	2	6	291	1	272	2e-54	190
rs:WP_031553494	methenyltetrahydrofolate cyclohydrolase [Parvularcula oceani].	44.03	293	152	5	1	291	1	283	2e-54	190
rs:WP_035120990	5,10-methylene-tetrahydrofolate cyclohydrolase [Cohnella panacarvi].	38.33	287	162	3	5	291	7	278	2e-54	189
rs:XP_002645175	C. briggsae CBR-DAO-3 protein, partial [Caenorhabditis briggsae].	41.83	306	157	8	1	295	1	296	2e-54	190
rs:WP_023162344	hypothetical protein [Clostridium autoethanogenum].	38.89	288	164	5	4	290	3	279	2e-54	190
tr:G5BD00_HETGA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:EHB07161.1}; Flags: Fragment;	43.19	257	138	3	41	293	1	253	2e-54	199
tr:B7DR14_9BACL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.03	284	163	4	3	286	30	300	2e-54	191
rs:WP_008514971	5,10-methylene-tetrahydrofolate dehydrogenase [Dethiobacter alkaliphilus].	39.08	284	161	3	1	284	1	272	2e-54	189
rs:XP_011589855	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Aquila chrysaetos canadensis].	41.67	264	146	3	34	293	10	269	2e-54	199
rs:WP_045550063	methenyltetrahydrofolate cyclohydrolase [Nocardioides luteus].	37.92	298	168	5	2	293	4	290	2e-54	190
rs:WP_005207896	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia sputi].	39.59	293	166	4	1	293	1	282	2e-54	190
tr:F4WF67_ACREC	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:EGI67118.1};	44.63	242	127	3	54	292	2	239	2e-54	199
rs:WP_029576327	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium thermacidophilum].	39.38	292	168	5	5	292	4	290	2e-54	190
tr:L8TT22_9MICC	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.31	295	173	5	4	294	17	306	2e-54	190
rs:XP_003099802	CRE-DAO-3 protein [Caenorhabditis remanei].	41.72	302	155	8	1	291	1	292	2e-54	190
rs:WP_013389775	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium bifidum].	38.70	292	170	5	6	293	5	291	2e-54	190
rs:WP_046284145	5,10-methylene-tetrahydrofolate cyclohydrolase [Mycobacterium sp. UM_NZ2].	38.57	293	166	2	1	293	1	279	2e-54	189
rs:WP_026900121	methenyltetrahydrofolate cyclohydrolase [Peptostreptococcaceae bacterium VA2].	39.24	288	163	4	4	290	9	285	2e-54	189
rs:WP_045922479	hypothetical protein [Lactobacillus mellis].	36.68	289	172	3	5	293	4	281	2e-54	189
rs:WP_014140265	5,10-methylene-tetrahydrofolate dehydrogenase [Kitasatospora setae].	36.64	292	171	2	2	293	8	285	2e-54	189
rs:WP_043786569	methenyltetrahydrofolate cyclohydrolase [Amycolatopsis rifamycinica].	39.25	293	167	4	1	293	1	282	2e-54	189
rs:WP_022877720	5,10-methylene-tetrahydrofolate dehydrogenase [Microbacterium sp. B19].	40.54	296	167	6	1	292	1	291	2e-54	190
rs:WP_006289074	5,10-methylene-tetrahydrofolate dehydrogenase [Parascardovia denticolens].	36.95	295	173	6	5	293	4	291	3e-54	189
rs:WP_045253143	methenyltetrahydrofolate cyclohydrolase [Microbacterium foliorum].	40.68	295	166	6	1	291	1	290	3e-54	189
rs:WP_035720099	methenyltetrahydrofolate cyclohydrolase [Gordonia shandongensis].	40.83	289	154	5	1	286	1	275	3e-54	189
rs:WP_026468921	methenyltetrahydrofolate cyclohydrolase [Amycolatopsis balhimycina].	39.59	293	166	4	1	293	1	282	3e-54	189
rs:WP_020057491	methenyltetrahydrofolate cyclohydrolase [alpha proteobacterium SCGC AAA076-C03].	37.50	280	168	3	14	293	14	286	3e-54	189
rs:WP_031128600	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL WC-3719].	37.59	290	165	3	6	293	1	276	3e-54	189
rs:WP_004833544	methenyltetrahydrofolate cyclohydrolase [Parvimonas micra].	37.24	290	170	5	5	293	4	282	3e-54	189
rs:WP_033255054	5,10-methylene-tetrahydrofolate cyclohydrolase [Kitasatospora phosalacinea].	36.43	291	171	2	3	293	8	284	3e-54	189
rs:XP_006932970	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Felis catus].	41.22	262	146	3	36	293	18	275	3e-54	199
rs:WP_030155078	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-244].	37.72	281	161	2	6	286	1	267	3e-54	189
tr:X1EP18_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_L01598 {ECO:0000313|EMBL:GAH35126.1}; Flags: Fragment;	51.12	178	87	0	87	264	2	179	3e-54	186
rs:WP_047298084	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium bifidum].	38.70	292	170	5	6	293	5	291	3e-54	189
rs:WP_035876315	methenyltetrahydrofolate cyclohydrolase [Cryobacterium sp. MLB-32].	38.05	297	175	6	1	293	1	292	3e-54	189
rs:WP_013363369	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium bifidum].	38.70	292	170	5	6	293	5	291	3e-54	189
gpu:CP011489_1997	5,10-methylenetetrahydrofolate dehydrogenase (NADP+); methenyltetrahydrofolate cyclohydrolase [Actinobacteria bacterium IMCC26256]	37.97	295	169	5	1	292	1	284	3e-54	189
rs:WP_032079646	methenyltetrahydrofolate cyclohydrolase [Clostridium drakei].	39.10	289	164	5	3	290	2	279	3e-54	189
rs:XP_007095268	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Panthera tigris altaica].	41.22	262	146	3	36	293	13	270	3e-54	199
rs:WP_033095955	5,10-methylene-tetrahydrofolate cyclohydrolase [Colwellia psychrerythraea].	36.82	296	172	4	1	295	1	282	3e-54	189
rs:WP_033494769	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium biavatii].	37.33	292	174	5	6	293	5	291	3e-54	189
rs:WP_031333309	methenyltetrahydrofolate cyclohydrolase [Williamsia sp. D3].	39.93	298	163	6	1	293	1	287	3e-54	189
tr:C1C1D0_CALCM	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:ACO15083.1};	38.57	293	171	5	4	289	6	296	4e-54	189
rs:WP_021275895	tetrahydrofolate dehydrogenase [Bacteriovorax sp. Seq25_V].	35.47	296	176	4	3	293	2	287	4e-54	189
rs:WP_021934599	bifunctional protein FolD [Peptostreptococcus anaerobius CAG:621].	39.86	291	163	5	4	293	21	300	4e-54	189
rs:WP_024631698	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Paenibacillus].	38.33	287	162	4	5	291	7	278	4e-54	189
rs:WP_015622937	methenyltetrahydrofolate cyclohydrolase [Actinoplanes sp. N902-109].	37.11	291	174	3	2	292	6	287	4e-54	189
rs:WP_022913865	5,10-methylene-tetrahydrofolate dehydrogenase [Frankia sp. Iso899].	38.11	286	164	5	1	286	1	273	4e-54	189
rs:WP_013222732	5,10-methylene-tetrahydrofolate dehydrogenase [Amycolatopsis mediterranei].	39.59	293	166	4	1	293	1	282	4e-54	189
rs:XP_009998971	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Chaetura pelagica].	41.67	264	146	3	34	293	10	269	4e-54	199
rs:WP_007470906	5,10-methylene-tetrahydrofolate dehydrogenase [Segniliparus rugosus].	36.30	292	175	5	1	292	1	281	4e-54	189
rs:WP_014909936	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Nocardiopsis].	40.21	286	160	5	1	286	1	275	4e-54	189
rs:XP_008371282	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X1 [Malus domestica].	39.46	294	172	2	2	293	54	343	4e-54	191
rs:XP_008371283	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X2 [Malus domestica].	39.46	294	172	2	2	293	53	342	4e-54	191
rs:WP_004695088	5,10-methylene-tetrahydrofolate dehydrogenase [Veillonella parvula].	37.41	278	160	3	6	283	4	267	4e-54	189
rs:WP_030720687	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-2580].	37.37	281	162	2	6	286	1	267	4e-54	189
rs:WP_039907515	methenyltetrahydrofolate cyclohydrolase [Micromonospora lupini].	36.59	287	173	3	6	292	1	278	4e-54	189
rs:WP_036451941	methenyltetrahydrofolate cyclohydrolase [Mycoplasma buteonis].	40.49	284	151	7	4	284	2	270	5e-54	188
rs:WP_005487259	methylenetetrahydrofolate dehydrogenase [Halanaerobium saccharolyticum].	37.54	285	163	4	6	290	4	273	5e-54	188
rs:WP_029678512	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium sp. 7101].	37.50	296	176	5	1	292	1	291	5e-54	189
rs:WP_033498545	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium coryneforme].	39.13	299	169	6	1	293	1	292	5e-54	189
rs:WP_008033378	methenyltetrahydrofolate cyclohydrolase [Rhodobacterales bacterium HTCC2255].	36.79	280	170	2	14	293	14	286	5e-54	189
rs:WP_039965247	5,10-methylene-tetrahydrofolate cyclohydrolase [Veillonella sp. 6_1_27].	37.41	278	160	3	6	283	4	267	5e-54	188
rs:WP_044580171	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces iranensis].	37.06	286	166	2	6	291	1	272	5e-54	188
tr:D6KQI2_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.41	278	160	3	6	283	8	271	6e-54	188
rs:WP_013360754	methenyltetrahydrofolate cyclohydrolase [[Clostridium] sticklandii].	39.86	291	163	4	3	292	2	281	6e-54	189
rs:WP_035752453	methenyltetrahydrofolate cyclohydrolase [Arthrobacter nitrophenolicus].	38.10	294	173	5	5	294	1	289	6e-54	189
rs:WP_002845424	tetrahydrofolate dehydrogenase [Peptostreptococcus anaerobius].	39.52	291	164	5	4	293	21	300	6e-54	189
rs:WP_042681344	methenyltetrahydrofolate cyclohydrolase [Anaerosalibacter sp. ND1].	38.41	289	166	5	3	290	2	279	6e-54	188
rs:XP_009988742	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Tauraco erythrolophus].	41.67	264	146	3	34	293	10	269	6e-54	198
rs:WP_028565599	methenyltetrahydrofolate cyclohydrolase [Salinispora tropica].	36.55	290	175	3	3	292	8	288	6e-54	189
rs:WP_010077105	tetrahydrofolate dehydrogenase [Clostridium cellulovorans].	35.86	290	175	2	4	293	3	281	7e-54	188
rs:WP_043165384	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium callitrichos].	37.67	292	173	5	6	293	5	291	7e-54	189
rs:WP_041953781	hypothetical protein [Parvimonas micra].	37.24	290	170	5	5	293	4	282	7e-54	188
rs:WP_033490206	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium indicum].	39.13	299	169	6	1	293	1	292	7e-54	189
sp:FOLD_NOCFA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	40.46	262	146	2	30	291	29	280	7e-54	188
rs:WP_046066043	methenyltetrahydrofolate cyclohydrolase [Clostridium scatologenes].	39.24	288	163	5	4	290	3	279	7e-54	188
rs:WP_005987509	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces graevenitzii].	38.26	298	170	6	2	293	8	297	7e-54	189
rs:WP_042428973	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptacidiphilus anmyonensis].	35.74	291	173	2	3	293	6	282	7e-54	188
sp:FOLD_DICTD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.02	287	163	3	5	291	4	278	7e-54	188
rs:WP_004123394	5,10-methylene-tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	38.70	292	170	5	5	292	4	290	8e-54	188
rs:WP_045309418	5,10-methylene-tetrahydrofolate cyclohydrolase [Lechevalieria aerocolonigenes].	39.44	284	153	4	13	293	9	276	8e-54	188
rs:WP_046323015	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium asteroides].	38.18	296	174	5	1	292	1	291	8e-54	189
rs:WP_004132914	5,10-methylene-tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	38.70	292	170	5	5	292	4	290	8e-54	188
sp:FOLD3_ROSDO	RecName: Full=Bifunctional protein FolD 3 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	36.33	278	171	2	15	292	12	283	8e-54	188
rs:WP_004122914	5,10-methylene-tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	38.70	292	170	5	5	292	4	290	8e-54	188
rs:WP_021148529	methylenetetrahydrofolate dehydrogenase [Veillonella parvula].	37.41	278	160	3	6	283	4	267	8e-54	188
rs:WP_043561111	methenyltetrahydrofolate cyclohydrolase [Actinomyces israelii].	39.25	293	169	6	3	291	9	296	8e-54	189
rs:WP_012802253	5,10-methylene-tetrahydrofolate dehydrogenase [Kytococcus sedentarius].	37.20	293	167	7	1	291	1	278	8e-54	188
tr:K0TBY9_THAOC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJK68022.1};	40.47	257	131	4	54	292	2	254	8e-54	187
rs:WP_035834975	methenyltetrahydrofolate cyclohydrolase [Cryobacterium roopkundense].	38.05	297	175	6	1	293	1	292	9e-54	188
rs:WP_021604550	tetrahydrofolate dehydrogenase [Actinomyces graevenitzii].	38.26	298	170	6	2	293	8	297	9e-54	189
rs:WP_034421126	methenyltetrahydrofolate cyclohydrolase [Clostridiales bacterium DRI-13].	37.37	289	169	4	5	292	4	281	9e-54	188
rs:XP_005072881	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Mesocricetus auratus].	40.21	286	159	6	15	293	28	308	1e-53	198
rs:WP_016444815	FolD protein [Actinomyces europaeus].	39.66	295	163	7	3	291	9	294	1e-53	188
tr:F0WH83_9STRA	SubName: Full=Bifunctional folD protein putative {ECO:0000313|EMBL:CCA20598.1};	36.86	274	165	3	1	272	1	268	1e-53	187
sp:FOLD_CLOK5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.68	287	164	4	5	290	4	279	1e-53	188
rs:WP_026460545	methenyltetrahydrofolate cyclohydrolase [Actinomyces suimastitidis].	40.20	296	164	6	2	291	8	296	1e-53	188
rs:WP_030923645	methenyltetrahydrofolate cyclohydrolase [Streptosporangium amethystogenes].	37.50	264	157	2	29	292	24	279	1e-53	187
tr:B9DYW3_CLOK1	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.68	287	164	4	5	290	12	287	1e-53	188
tr:A0A077LY86_9MICO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.88	293	174	5	1	293	1	285	1e-53	188
rs:WP_041133111	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces vietnamensis].	36.30	292	172	2	2	293	5	282	1e-53	187
rs:WP_015021960	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium asteroides].	37.50	296	176	5	1	292	1	291	1e-53	188
rs:WP_019071808	hypothetical protein [Streptomyces sp. R1-NS-10].	40.21	291	162	3	6	295	5	284	1e-53	187
rs:WP_043900114	methylenetetrahydrofolate dehydrogenase, partial [Candidatus Arthromitus sp. SFB-5].	42.13	235	125	2	54	288	4	227	1e-53	186
rs:WP_004130520	5,10-methylene-tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	38.70	292	170	5	5	292	4	290	1e-53	188
rs:WP_030316876	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces flavochromogenes].	36.64	292	171	2	2	293	5	282	1e-53	187
rs:WP_035811228	hypothetical protein [Jeotgalicoccus sp. 13MG44_air].	38.57	293	168	5	5	296	4	285	1e-53	187
rs:WP_018227279	hypothetical protein [actinobacterium SCGC AAA023-D18].	38.28	290	165	5	1	290	1	276	1e-53	187
rs:WP_008703871	MULTISPECIES: tetrahydrofolate dehydrogenase [Clostridiales].	39.37	287	162	4	8	293	7	282	1e-53	187
rs:WP_028273672	hypothetical protein [Atopococcus tabaci].	39.86	286	160	5	6	290	4	278	1e-53	187
tr:H7DKC6_9CLOT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.13	235	125	2	54	288	4	227	1e-53	186
tr:V8NWL5_OPHHA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:ETE66048.1}; Flags: Fragment;	39.53	296	140	4	2	293	51	311	1e-53	197
rs:WP_045921327	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium coryneforme].	39.13	299	169	6	1	293	14	305	1e-53	189
rs:WP_027287562	methenyltetrahydrofolate cyclohydrolase [Rhodovibrio salinarum].	34.04	285	181	3	6	290	1	278	2e-53	188
rs:WP_036299226	methenyltetrahydrofolate cyclohydrolase [Microbacterium sp. C448].	38.46	299	172	5	1	293	1	293	2e-53	187
rs:WP_035957525	5,10-methylene-tetrahydrofolate cyclohydrolase [Kitasatospora sp. NRRL B-11411].	36.81	288	168	2	6	293	1	274	2e-53	187
rs:WP_026005777	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. AK-YN10].	38.31	295	173	5	3	293	5	294	2e-53	187
rs:WP_029509619	methenyltetrahydrofolate cyclohydrolase [Leuconostoc lactis].	39.59	293	158	5	4	292	3	280	2e-53	187
rs:WP_016359431	MULTISPECIES: methylenetetrahydrofolate dehydrogenase [Arthrobacter].	38.31	295	173	5	3	293	16	305	2e-53	188
rs:XP_010286271	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Phaethon lepturus].	42.41	257	140	3	41	293	1	253	2e-53	197
tr:A0A077Z6H2_TRITR	SubName: Full=C 1 tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:CDW56077.1};	39.86	296	165	6	3	293	2	289	2e-53	197
rs:WP_037851733	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-1824].	35.76	288	171	2	6	293	1	274	2e-53	187
rs:WP_040929000	hypothetical protein [Nosocomiicoccus sp. NP2].	40.07	287	160	5	3	288	2	277	2e-53	187
rs:WP_044346493	methenyltetrahydrofolate cyclohydrolase [Desulfarculus sp. SPR].	39.04	292	165	5	1	290	1	281	2e-53	187
rs:WP_016799410	tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	38.70	292	170	5	5	292	4	290	2e-53	187
tr:A0A0A0NX48_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.36	286	168	2	6	291	1	272	2e-53	187
rs:XP_003267686	PREDICTED: LOW QUALITY PROTEIN: c-1-tetrahydrofolate synthase, cytoplasmic [Nomascus leucogenys].	44.77	239	124	3	59	293	136	370	2e-53	198
rs:WP_026245768	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. HmicA12].	35.96	292	173	2	2	293	6	283	2e-53	187
rs:NP_509362	DAO-3 [Caenorhabditis elegans].	41.00	300	160	7	1	291	1	292	3e-53	187
rs:WP_038125694	5,10-methylene-tetrahydrofolate cyclohydrolase [Veillonella sp. 3_1_44].	37.32	276	159	3	8	283	6	267	3e-53	186
tr:D6KK16_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.32	276	159	3	8	283	10	271	3e-53	187
rs:WP_006861144	tetrahydrofolate dehydrogenase [Marvinbryantia formatexigens].	39.02	287	163	4	8	293	7	282	3e-53	187
rs:WP_010000146	methenyltetrahydrofolate cyclohydrolase [Leuconostoc lactis].	39.59	293	158	5	4	292	3	280	3e-53	187
rs:WP_013916086	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus mucilaginosus].	37.50	288	165	3	5	292	6	278	3e-53	187
rs:WP_036221499	hypothetical protein [Mesoaciditoga lauensis].	36.55	290	167	6	1	290	1	273	3e-53	186
rs:WP_035855407	methenyltetrahydrofolate cyclohydrolase [Cryptosporangium arvum].	37.32	284	169	3	1	284	1	275	3e-53	187
rs:WP_014676705	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces hygroscopicus].	37.46	291	168	2	3	293	4	280	3e-53	187
rs:WP_045924559	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium asteroides].	37.50	296	176	5	1	292	1	291	3e-53	187
tr:A0A0C7QE61_CLOSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.64	283	154	6	13	292	30	301	3e-53	187
rs:XP_004900119	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X4 [Heterocephalus glaber].	43.14	255	138	3	11	259	1	254	3e-53	187
rs:WP_024758036	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces exfoliatus].	36.30	292	172	2	2	293	5	282	3e-53	186
rs:WP_020256364	hypothetical protein, partial [Candidatus Paceibacter normanii].	39.53	258	141	4	36	291	13	257	3e-53	186
rs:WP_027308911	methenyltetrahydrofolate cyclohydrolase [Caloramator sp. ALD01].	39.66	290	163	5	5	293	2	280	3e-53	186
rs:WP_018666392	methylenetetrahydrofolate dehydrogenase [Thermobrachium celere].	39.37	287	162	5	5	290	2	277	3e-53	186
tr:X0XZQ8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S31749 {ECO:0000313|EMBL:GAG30201.1}; Flags: Fragment;	53.37	178	76	1	114	291	2	172	3e-53	183
tr:G1RVL5_NOMLE	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSNLEP00000017292};	44.54	238	124	3	60	293	5	238	3e-53	196
rs:WP_019161829	tetrahydrofolate dehydrogenase [Ruminococcus sp. JC304].	39.02	287	163	4	8	293	7	282	3e-53	186
tr:V8CTN8_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.60	298	164	6	1	293	16	302	3e-53	187
rs:XP_010206860	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Colius striatus].	41.67	264	146	3	34	293	10	269	3e-53	196
tr:E2B989_HARSA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:EFN87737.1};	44.21	242	128	3	54	292	2	239	3e-53	196
tr:F3GEE0_PSESJ	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EGH45440.1}; EC=1.5.1.5 {ECO:0000313|EMBL:EGH45440.1}; Flags: Fragment;	45.34	236	124	2	1	236	1	231	4e-53	185
rs:WP_027333630	methenyltetrahydrofolate cyclohydrolase [Mycoplasma glycophilum].	40.14	289	149	8	4	286	2	272	4e-53	186
rs:XP_007985146	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Chlorocebus sabaeus].	39.32	295	151	6	3	293	112	382	4e-53	197
sp:FOLD1_COLP3	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.11	291	168	4	1	290	1	277	4e-53	186
rs:WP_014486513	methenyltetrahydrofolate cyclohydrolase [Brachyspira intermedia].	36.46	288	169	3	3	290	2	275	4e-53	186
rs:WP_015796600	5,10-methylene-tetrahydrofolate dehydrogenase [Catenulispora acidiphila].	38.54	288	162	3	5	292	2	274	4e-53	186
tr:W4PES0_9BACE	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:GAE17878.1};	47.19	178	94	0	5	182	3	180	4e-53	183
rs:WP_003356589	bifunctional protein FolD [Clostridium botulinum].	37.88	293	166	6	3	292	2	281	4e-53	186
rs:WP_028306746	methenyltetrahydrofolate cyclohydrolase [Desulfitibacter alkalitolerans].	38.41	289	168	4	3	290	2	281	4e-53	186
rs:WP_039702937	methenyltetrahydrofolate cyclohydrolase [marine actinobacterium MedAcidi-G2A].	35.96	292	178	3	1	292	1	283	4e-53	186
tr:K2G1M6_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.25	285	159	5	5	288	2	270	4e-53	186
rs:WP_013103713	methenyltetrahydrofolate cyclohydrolase [Leuconostoc kimchii].	40.41	292	155	6	4	291	3	279	5e-53	186
rs:WP_029948916	hypothetical protein [Parvimonas micra].	36.90	290	171	5	5	293	4	282	5e-53	186
rs:WP_045882557	methenyltetrahydrofolate cyclohydrolase [Clostridium botulinum].	37.88	293	166	6	3	292	2	281	5e-53	186
rs:WP_022380771	bifunctional protein FolD [Ruminococcus sp. CAG:9].	39.02	287	163	4	8	293	7	282	5e-53	186
rs:WP_030552227	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces exfoliatus].	36.30	292	172	2	2	293	5	282	5e-53	186
rs:WP_027503763	methenyltetrahydrofolate cyclohydrolase [Rhodococcus sp. UNC23MFCrub1.1].	39.27	303	159	7	1	293	1	288	5e-53	186
rs:WP_031273357	methenyltetrahydrofolate cyclohydrolase [Curtobacterium sp. B8].	36.79	299	175	5	2	293	11	302	5e-53	186
rs:XP_008395306	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Poecilia reticulata].	46.41	209	104	3	87	291	4	208	5e-53	184
rs:WP_016636133	tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	38.70	292	170	5	5	292	4	290	5e-53	186
rs:WP_022513091	bifunctional protein FolD [Dialister sp. CAG:588].	39.07	279	157	4	4	282	2	267	6e-53	186
sp:FOLD_CLOBL	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.14	291	168	5	3	292	2	281	6e-53	186
rs:WP_038299142	methenyltetrahydrofolate cyclohydrolase [[Clostridium] mangenotii].	37.37	289	169	5	3	290	8	285	6e-53	186
rs:WP_045822264	methenyltetrahydrofolate cyclohydrolase [Williamsia sp. ARP1].	40.42	287	154	6	1	284	7	279	6e-53	186
rs:XP_009141751	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X2 [Brassica rapa].	42.55	235	125	4	5	235	65	293	6e-53	186
tr:E9QC23_DANRE	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSDARP00000123417};	40.41	245	140	2	3	241	51	295	6e-53	186
rs:WP_003994042	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces viridochromogenes].	35.96	292	173	2	2	293	6	283	6e-53	186
sp:FOLD_CLOB1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.14	291	168	5	3	292	2	281	7e-53	186
rs:WP_041762488	methenyltetrahydrofolate cyclohydrolase [Pseudonocardia dioxanivorans].	40.07	292	164	4	1	292	1	281	7e-53	186
sp:FOLD_TROWT	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.11	286	172	4	1	286	1	281	7e-53	186
rs:WP_030216882	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces griseoluteus].	36.30	292	172	2	2	293	5	282	7e-53	186
rs:WP_009372587	methenyltetrahydrofolate cyclohydrolase [Parvimonas sp. oral taxon 110].	36.90	290	171	5	5	293	4	282	8e-53	186
sp:FOLD_ALKOO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.72	289	168	4	3	290	2	279	8e-53	186
rs:WP_024933850	bifunctional protein FolD [Clostridium botulinum].	38.14	291	168	5	3	292	2	281	8e-53	186
sp:FOLD_CLOBJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.88	293	166	6	3	292	2	281	8e-53	186
rs:WP_030690193	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces globisporus].	35.96	292	173	2	2	293	5	282	8e-53	186
rs:WP_031079474	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL S-118].	36.90	290	167	3	6	293	1	276	8e-53	185
rs:WP_023363861	methylenetetrahydrofolate dehydrogenase [Actinoplanes friuliensis].	37.20	293	169	4	3	292	7	287	8e-53	186
rs:WP_025775794	methenyltetrahydrofolate cyclohydrolase [Clostridium botulinum].	38.14	291	168	5	3	292	2	281	8e-53	185
rs:WP_045539418	methenyltetrahydrofolate cyclohydrolase [Clostridium botulinum].	38.14	291	168	5	3	292	2	281	8e-53	185
rs:WP_013975142	methenyltetrahydrofolate cyclohydrolase [Leuconostoc sp. C2].	39.73	292	157	5	4	291	3	279	8e-53	185
tr:U6NRS0_HAECO	SubName: Full=Tetrahydrofolate dehydrogenase cyclohydrolase domain containing protein {ECO:0000313|EMBL:CDJ82637.1};	43.79	306	134	11	1	285	1	289	9e-53	186
rs:WP_026929336	5,10-methylene-tetrahydrofolate cyclohydrolase [Glycomyces tenuis].	37.50	288	168	4	6	293	4	279	9e-53	185
rs:WP_038104284	methenyltetrahydrofolate cyclohydrolase [Tropheryma whipplei].	38.11	286	172	4	1	286	1	281	9e-53	186
tr:A0A010NDY4_9MICC	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.18	296	168	8	5	293	20	307	9e-53	186
rs:WP_033377156	methenyltetrahydrofolate cyclohydrolase [Metascardovia criceti].	38.97	290	168	6	6	291	1	285	9e-53	186
sp:FOLD_TROW8	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.11	286	172	4	1	286	1	281	9e-53	186
rs:WP_045935469	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium asteroides].	36.82	296	178	5	1	292	1	291	9e-53	186
tr:A0A024H4I7_9MICC	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.53	296	166	6	2	291	7	295	1e-52	186
rs:WP_018592062	methenyltetrahydrofolate cyclohydrolase [Terrisporobacter glycolicus].	37.80	291	170	4	3	292	2	282	1e-52	185
rs:WP_004113155	5,10-methylene-tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	38.70	292	170	5	5	292	4	290	1e-52	186
tr:W4PS51_9BACE	SubName: Full=Mg(2+) chelatase family protein {ECO:0000313|EMBL:GAE22490.1};	46.93	179	95	0	5	183	3	181	1e-52	182
tr:A0A075AXI8_9FUNG	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase domain-containing protein {ECO:0000313|EMBL:EPZ34962.1}; EC=1.5.1.5 {ECO:0000313|EMBL:EPZ34962.1};	37.74	265	152	2	19	274	22	282	1e-52	185
rs:WP_031260236	methenyltetrahydrofolate cyclohydrolase [Curtobacterium flaccumfaciens].	36.79	299	175	5	2	293	11	302	1e-52	186
rs:WP_039678500	methenyltetrahydrofolate cyclohydrolase [Terrisporobacter othiniensis].	37.80	291	170	4	3	292	2	282	1e-52	185
rs:WP_007728713	MULTISPECIES: methylenetetrahydrofolate dehydrogenase [Rhodococcus].	38.46	286	162	2	1	286	21	292	1e-52	186
tr:A0A022LT45_9MICO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.79	299	175	5	2	293	15	306	1e-52	186
tr:A0A087E9P3_9BIFI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.64	295	166	7	6	293	7	293	1e-52	186
tr:L5KE65_PTEAL	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:ELK09855.1};	38.18	296	161	5	3	293	173	451	1e-52	196
rs:WP_024462893	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium subtile].	38.64	295	166	7	6	293	5	291	1e-52	186
rs:WP_004114841	5,10-methylene-tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	38.70	292	170	5	5	292	4	290	1e-52	185
rs:WP_018032952	MULTISPECIES: hypothetical protein [unclassified Crenarchaeota (miscellaneous)].	34.95	289	175	4	5	293	4	279	1e-52	185
rs:WP_019681980	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas aeruginosa].	52.60	173	72	2	118	290	6	168	1e-52	181
tr:A0A0D2ZVY5_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo02178s010.1};	38.91	293	167	5	2	291	50	333	1e-52	186
rs:WP_019261778	5,10-methylene-tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	38.70	292	170	5	5	292	4	290	1e-52	185
tr:J7SVU8_CLOSG	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.88	293	170	5	1	292	1	282	1e-52	185
rs:WP_020759463	tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	38.70	292	170	5	5	292	4	290	1e-52	185
rs:WP_004794250	methenyltetrahydrofolate cyclohydrolase [Mycoplasma canis].	38.62	290	161	7	4	290	2	277	2e-52	184
rs:WP_036476894	methenyltetrahydrofolate cyclohydrolase [Nesterenkonia sp. AN1].	37.84	296	169	8	5	293	1	288	2e-52	185
tr:D6AGL9_STRFL	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EFE77029.2}; Flags: Fragment;	40.08	237	139	2	1	237	1	234	2e-52	184
tr:A0A099P6Q8_ISSOR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGK39904.1};	37.16	296	163	6	1	292	1	277	2e-52	184
tr:W4PAK3_9BACE	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:GAE16403.1};	48.84	172	88	0	5	176	3	174	2e-52	181
rs:WP_020761284	tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	38.70	292	170	5	5	292	4	290	2e-52	185
rs:WP_039239419	5,10-methylene-tetrahydrofolate cyclohydrolase [Arthrobacter sp. MWB30].	35.05	291	178	3	1	291	1	280	2e-52	185
sp:FOLD_BRAHW	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	36.43	291	171	3	3	293	2	278	2e-52	184
tr:G0UPJ9_TRYCI	SubName: Full=Putative uncharacterized protein TCIL3000_7_1130 {ECO:0000313|EMBL:CCC91310.1};	36.36	297	178	5	3	293	4	295	2e-52	185
rs:WP_015038436	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces venezuelae].	35.96	292	173	2	2	293	5	282	2e-52	184
rs:WP_027466642	methenyltetrahydrofolate cyclohydrolase [Curtobacterium sp. UNCCL17].	36.27	295	174	5	6	293	1	288	2e-52	184
tr:K3WRC4_PYTUL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblProtists:PYU1_T007518};	39.50	281	130	5	47	291	58	334	2e-52	186
rs:WP_012877536	5,10-methylene-tetrahydrofolate dehydrogenase [Xylanimonas cellulosilytica].	38.80	299	170	6	1	293	1	292	2e-52	185
rs:WP_044942503	methenyltetrahydrofolate cyclohydrolase [Blautia schinkii].	38.95	285	162	4	8	291	7	280	2e-52	184
rs:WP_042491258	bifunctional protein FolD [Tropheryma whipplei].	38.11	286	172	4	1	286	1	281	2e-52	185
rs:WP_009144562	5,10-methylene-tetrahydrofolate dehydrogenase [Phascolarctobacterium succinatutens].	38.16	283	162	4	1	283	1	270	2e-52	184
rs:WP_029289710	methenyltetrahydrofolate cyclohydrolase [Cellulomonas sp. HZM].	39.66	295	169	6	1	291	1	290	2e-52	184
rs:WP_005423502	MULTISPECIES: tetrahydrofolate dehydrogenase [Clostridiales].	39.02	287	163	4	8	293	7	282	2e-52	184
rs:WP_046528873	methenyltetrahydrofolate cyclohydrolase [Cellulomonas sp. FA1].	40.60	298	164	6	1	292	1	291	2e-52	184
rs:WP_030034318	methenyltetrahydrofolate cyclohydrolase [Clostridium botulinum].	37.80	291	169	5	3	292	2	281	2e-52	184
rs:WP_015287407	bifunctional protein FolD [Mycoplasma cynos].	39.18	291	158	8	4	290	2	277	2e-52	184
rs:WP_013734150	5,10-methylene-tetrahydrofolate dehydrogenase [Verrucosispora maris].	35.74	291	178	3	2	292	4	285	3e-52	184
sp:FOLD_CLOBM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.80	291	169	5	3	292	2	281	3e-52	184
rs:WP_047116909	methenyltetrahydrofolate cyclohydrolase [Brachyspira hyodysenteriae].	36.43	291	171	3	3	293	2	278	3e-52	184
rs:WP_033126938	methenyltetrahydrofolate cyclohydrolase [Eubacterium sp. ER2].	38.68	287	164	4	5	290	4	279	3e-52	184
rs:WP_028463459	methenyltetrahydrofolate cyclohydrolase [Nocardia sp. 348MFTsu5.1].	40.27	298	162	6	1	293	4	290	3e-52	184
sp:FOLD_CLOB6	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.80	291	169	5	3	292	2	281	3e-52	184
tr:D4LTL0_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.02	287	163	4	8	293	7	282	3e-52	184
rs:WP_046657161	methenyltetrahydrofolate cyclohydrolase, partial [Escherichia coli].	52.13	188	80	3	110	297	6	183	3e-52	181
tr:A0A0C7PME2_CLOSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.02	289	170	5	3	290	8	285	3e-52	184
rs:WP_006292993	5,10-methylene-tetrahydrofolate dehydrogenase [Scardovia inopinata].	37.04	297	174	6	3	293	2	291	3e-52	184
tr:F4CUX9_PSEUX	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.73	292	165	4	1	292	4	284	3e-52	184
rs:WP_040617408	methenyltetrahydrofolate cyclohydrolase [Roseibium sp. TrichSKD4].	35.25	278	174	2	15	292	16	287	3e-52	184
rs:WP_030337389	methenyltetrahydrofolate cyclohydrolase [Micromonospora parva].	38.22	259	152	2	34	292	28	278	3e-52	184
rs:WP_040691808	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia vinacea].	37.98	287	167	3	6	292	6	281	3e-52	184
tr:X1KPR0_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C01115 {ECO:0000313|EMBL:GAH92149.1}; Flags: Fragment;	44.55	220	108	3	74	290	2	210	3e-52	182
rs:WP_012937520	methenyltetrahydrofolate cyclohydrolase [Acidaminococcus fermentans].	38.73	284	157	3	1	284	1	267	3e-52	184
gp:CP003234_3102	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase [Mycobacterium tuberculosis RGTB423]	38.65	282	162	4	1	282	25	295	3e-52	184
sp:FOLD_KINRD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.19	296	171	5	1	292	1	291	3e-52	184
rs:WP_035292155	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. KNHs214].	38.75	289	165	5	3	290	2	279	3e-52	184
gp:CP003233_3154	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase [Mycobacterium tuberculosis RGTB327]	38.65	282	162	4	1	282	25	295	3e-52	184
tr:X1UQ75_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_S23603 {ECO:0000313|EMBL:GAJ19654.1}; Flags: Fragment;	54.02	174	73	1	120	293	1	167	3e-52	180
tr:A0A069JBY1_9NOCA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.81	286	161	2	1	286	1	272	3e-52	184
rs:WP_038503103	methenyltetrahydrofolate cyclohydrolase [Rhodoluna lacicola].	37.88	293	172	5	1	289	1	287	4e-52	184
rs:WP_047103806	methenyltetrahydrofolate cyclohydrolase [Brachyspira hyodysenteriae].	36.43	291	171	3	3	293	2	278	4e-52	184
rs:WP_044806975	methenyltetrahydrofolate cyclohydrolase, partial [Escherichia coli].	53.33	180	74	3	110	289	1	170	4e-52	180
rs:WP_030536751	5,10-methylene-tetrahydrofolate cyclohydrolase [Rhodococcus erythropolis].	38.46	286	162	2	1	286	21	292	4e-52	185
rs:WP_028829321	methenyltetrahydrofolate cyclohydrolase [Proteocatella sphenisci].	37.07	294	173	5	1	293	1	283	4e-52	184
tr:R5HXU3_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.68	287	164	4	8	293	7	282	4e-52	184
tr:E2CQX6_9RHOB	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.25	278	174	2	15	292	31	302	4e-52	184
rs:WP_013244182	methenyltetrahydrofolate cyclohydrolase [Brachyspira pilosicoli].	37.76	286	164	4	1	286	1	272	4e-52	184
rs:WP_015746591	5,10-methylene-tetrahydrofolate dehydrogenase [Nakamurella multipartita].	39.73	297	166	5	1	297	1	284	4e-52	184
rs:WP_013600271	5,10-methylene-tetrahydrofolate dehydrogenase [Arthrobacter phenanthrenivorans].	39.52	291	163	6	2	286	7	290	4e-52	184
rs:WP_032405957	methenyltetrahydrofolate cyclohydrolase [Rhodococcus fascians].	38.72	266	153	3	28	293	32	287	4e-52	184
tr:F1SA74_PIG	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSSCP00000002464}; Flags: Fragment;	39.43	279	160	4	15	290	15	287	5e-52	193
rs:WP_026858663	hypothetical protein [Jeotgalicoccus psychrophilus].	38.10	294	168	6	5	296	4	285	5e-52	184
rs:WP_024252496	methenyltetrahydrofolate cyclohydrolase, partial [Escherichia coli].	53.33	180	74	3	110	289	4	173	5e-52	180
rs:WP_009828953	methenyltetrahydrofolate cyclohydrolase [Rhodobacteraceae bacterium HTCC2083].	35.99	289	175	3	5	293	10	288	5e-52	184
rs:WP_029749089	hypothetical protein, partial [Marinimicrobia bacterium JGI 0000113-D11].	45.26	190	103	1	61	250	2	190	5e-52	181
rs:WP_033517032	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium scardovii].	36.99	292	175	5	6	293	5	291	5e-52	184
rs:WP_012224010	5,10-methylene-tetrahydrofolate dehydrogenase [Candidatus Microthrix parvicella].	33.56	298	185	3	1	293	1	290	5e-52	184
rs:WP_044700450	methenyltetrahydrofolate cyclohydrolase, partial [Escherichia coli].	53.33	180	74	3	110	289	6	175	5e-52	180
tr:C8WXG8_ALIAD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.32	284	165	4	3	286	4	274	5e-52	183
tr:A0A0D2PQR0_GOSRA	SubName: Full=Gossypium raimondii chromosome 1, whole genome shotgun sequence {ECO:0000313|EMBL:KJB09239.1};	42.13	235	130	2	3	235	76	306	5e-52	184
rs:WP_006546061	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces coleocanis].	37.63	295	169	6	3	291	9	294	5e-52	184
rs:WP_041708130	methenyltetrahydrofolate cyclohydrolase [Alicyclobacillus acidocaldarius].	37.32	284	165	4	3	286	2	272	5e-52	183
rs:WP_014932050	methylenetetrahydrofolate dehydrogenase [Brachyspira pilosicoli].	37.76	286	164	4	1	286	1	272	6e-52	183
rs:WP_042385334	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Clostridium].	37.80	291	169	5	3	292	2	281	6e-52	183
rs:WP_009357613	methylenetetrahydrofolate dehydrogenase [Arthrobacter nitrophenolicus].	34.83	290	178	3	1	290	1	279	6e-52	183
rs:WP_039708450	methenyltetrahydrofolate cyclohydrolase [marine actinobacterium MedAcidi-G1].	36.86	293	176	3	1	293	1	284	6e-52	183
rs:WP_004127956	5,10-methylene-tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	37.50	296	170	6	5	293	4	291	6e-52	183
rs:WP_025359941	5,10-methylene-tetrahydrofolate cyclohydrolase [Kutzneria albida].	39.58	288	156	5	5	291	3	273	6e-52	183
rs:WP_004697513	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Veillonella].	36.23	276	162	3	8	283	6	267	6e-52	183
rs:WP_021720155	bifunctional protein FolD [Phascolarctobacterium succinatutens].	37.81	283	163	4	1	283	1	270	6e-52	183
rs:WP_008721704	methylenetetrahydrofolate dehydrogenase [Brachyspira hampsonii].	35.99	289	171	3	5	293	4	278	7e-52	183
sp:FOLD_LEUCK	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.91	293	158	6	4	291	3	279	7e-52	183
rs:WP_034508687	methenyltetrahydrofolate cyclohydrolase, partial [Agrobacterium rhizogenes].	49.51	206	96	4	91	292	2	203	7e-52	181
tr:U0E6P4_9NOCA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.81	286	161	2	1	286	1	272	7e-52	183
rs:WP_033338361	methenyltetrahydrofolate cyclohydrolase [Catenuloplanes japonicus].	38.01	292	172	3	1	292	1	283	7e-52	183
rs:WP_020377656	hypothetical protein [Candidatus Microthrix parvicella].	33.56	298	185	3	1	293	1	290	7e-52	183
tr:L9LAQ5_TUPCH	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:ELW70832.1};	43.19	257	120	5	38	290	17	251	8e-52	192
rs:WP_040735870	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia tenerifensis].	41.31	259	142	2	34	292	33	281	8e-52	183
tr:A0A0C7M767_CLOSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.68	289	171	5	3	290	8	285	8e-52	183
rs:WP_003490293	methenyltetrahydrofolate cyclohydrolase [Clostridium sporogenes].	37.46	291	170	5	3	292	2	281	9e-52	182
rs:XP_002507522	5,10-methylene-tetrahydrofolate dehydrogenase/cyclohydrolase [Micromonas sp. RCC299].	33.82	343	174	6	2	294	56	395	9e-52	186
rs:WP_037908861	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces yeochonensis].	36.30	292	172	2	2	293	6	283	9e-52	183
rs:WP_029125724	methenyltetrahydrofolate cyclohydrolase [Salinispora tropica].	36.62	284	171	3	3	286	8	282	9e-52	183
rs:WP_039503331	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Prauserella sp. Am3].	37.54	285	162	5	6	289	4	273	9e-52	182
rs:WP_037771468	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. FXJ7.023].	35.40	291	174	2	3	293	7	283	9e-52	183
rs:WP_036464736	methenyltetrahydrofolate cyclohydrolase [Mycoplasma sturni].	39.58	288	151	8	4	286	2	271	9e-52	182
rs:XP_001745304	hypothetical protein [Monosiga brevicollis MX1].	40.40	297	140	6	3	292	2	268	9e-52	192
tr:M5FYB4_DACSP	SubName: Full=FTHFS-domain-containing protein {ECO:0000313|EMBL:EJU00820.1};	40.86	301	164	7	1	292	21	316	1e-51	193
rs:WP_028934079	methenyltetrahydrofolate cyclohydrolase [Pseudonocardia spinosispora].	35.74	291	178	3	2	292	11	292	1e-51	183
rs:WP_021977713	bifunctional protein FolD [Ruminococcus sp. CAG:17].	38.95	285	162	4	8	291	7	280	1e-51	182
rs:WP_031322007	methenyltetrahydrofolate cyclohydrolase [Rhodobacteraceae bacterium PD-2].	37.28	279	167	3	15	292	13	284	1e-51	183
rs:WP_025435983	methenyltetrahydrofolate cyclohydrolase [Eubacterium acidaminophilum].	38.06	289	169	4	3	290	2	281	1e-51	182
rs:XP_011330627	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like isoform X2 [Cerapachys biroi].	36.98	338	163	5	3	292	24	359	1e-51	185
rs:WP_020126381	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. 303MFCol5.2].	35.27	292	175	2	2	293	6	283	1e-51	182
rs:WP_009350992	5,10-methylene-tetrahydrofolate dehydrogenase [Veillonella sp. oral taxon 158].	36.59	276	161	3	8	283	6	267	1e-51	182
tr:D0WNQ7_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.85	296	168	6	2	291	15	303	1e-51	183
rs:WP_024627350	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium sp. A11].	36.82	296	178	5	1	292	1	291	1e-51	183
rs:WP_026942598	methenyltetrahydrofolate cyclohydrolase [Hellea balneolensis].	38.30	282	163	5	16	293	13	287	1e-51	183
rs:WP_022067201	bifunctional protein FolD [Blautia sp. CAG:257].	38.68	287	164	4	8	293	7	282	1e-51	182
rs:WP_003021444	tetrahydrofolate dehydrogenase [Blautia hansenii].	38.57	293	152	6	8	291	7	280	1e-51	182
rs:WP_014935055	methenyltetrahydrofolate cyclohydrolase [Brachyspira pilosicoli].	37.41	286	165	4	1	286	1	272	1e-51	182
rs:XP_004699057	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Echinops telfairi].	43.15	241	129	3	57	293	81	317	1e-51	192
rs:WP_029930553	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia otitidiscaviarum].	40.93	259	143	2	34	292	33	281	1e-51	182
rs:WP_039798607	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia araoensis].	39.62	265	150	2	27	291	26	280	1e-51	182
rs:WP_043057539	methenyltetrahydrofolate cyclohydrolase [Mesorhizobium sp. UASWS1009].	38.91	293	163	7	1	286	1	284	1e-51	182
rs:WP_044823344	methenyltetrahydrofolate cyclohydrolase [Clostridium aceticum].	37.46	291	170	4	3	292	2	281	1e-51	182
rs:WP_004902503	methenyltetrahydrofolate cyclohydrolase [Leuconostoc citreum].	38.91	293	158	6	4	291	3	279	1e-51	182
tr:A0A0C7P217_CLOSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.68	289	171	5	3	290	8	285	1e-51	182
tr:A0A099Y2J1_9FLAO	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:KGL63732.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KGL63732.1}; EC=3.5.4.9 {ECO:0000313|EMBL:KGL63732.1};	44.75	219	121	0	5	223	3	221	1e-51	180
rs:WP_021651424	tetrahydrofolate dehydrogenase [Blautia sp. KLE 1732].	38.95	285	162	4	8	291	7	280	1e-51	182
rs:XP_011330626	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like isoform X1 [Cerapachys biroi].	36.98	338	163	5	3	292	36	371	1e-51	185
tr:A0A0A8W600_CLOSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.68	289	171	5	3	290	8	285	1e-51	182
rs:WP_013882988	5,10-methylene-tetrahydrofolate dehydrogenase [[Cellvibrio] gilvus].	40.34	295	167	6	1	291	1	290	1e-51	182
rs:WP_022270087	bifunctional protein FolD [Firmicutes bacterium CAG:424].	38.91	293	151	5	8	291	7	280	1e-51	182
rs:WP_045884138	methenyltetrahydrofolate cyclohydrolase [Clostridium sporogenes].	37.46	291	170	5	3	292	2	281	2e-51	182
rs:WP_026922570	5,10-methylene-tetrahydrofolate cyclohydrolase [Glycomyces arizonensis].	38.25	285	164	4	6	290	4	276	2e-51	182
tr:T5HPT7_RHOER	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.81	286	161	2	1	286	1	272	2e-51	182
rs:WP_027218921	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio fibrisolvens].	39.18	291	166	4	3	292	2	282	2e-51	182
tr:D4LHV7_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.95	285	162	4	8	291	7	280	2e-51	182
tr:C1A0B6_RHOE4	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.81	286	161	2	1	286	1	272	2e-51	182
tr:A0A0C7RCY3_CLOSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.68	289	171	5	3	290	8	285	2e-51	182
rs:XP_004357479	methenyltetrahydrofolate cyclohydrolase [Acanthamoeba castellanii str. Neff].	43.78	249	114	7	54	291	2	235	2e-51	181
tr:A0A0C7G3C0_CLOSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.68	289	171	5	3	290	8	285	2e-51	182
tr:A0A0C7TA74_CLOSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.02	289	170	5	3	290	8	285	2e-51	182
rs:WP_010278569	methenyltetrahydrofolate cyclohydrolase [Leuconostoc pseudomesenteroides].	37.11	291	164	5	4	290	3	278	2e-51	182
rs:WP_040177305	bifunctional protein FolD [Leuconostoc citreum].	38.57	293	159	6	4	291	3	279	2e-51	182
rs:WP_033059060	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Clostridium].	37.11	291	171	5	3	292	2	281	2e-51	182
sp:FOLD1_SALTO	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	36.62	284	171	3	3	286	8	282	2e-51	182
tr:A0A0C7H8N2_CLOSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.68	289	171	5	3	290	8	285	2e-51	182
rs:WP_028568624	bifunctional protein FolD [Salinispora tropica].	36.62	284	171	3	3	286	8	282	2e-51	182
rs:WP_040323227	methenyltetrahydrofolate cyclohydrolase [Actinomyces sp. oral taxon 848].	39.04	292	165	6	6	291	1	285	2e-51	182
rs:WP_019925790	hypothetical protein [Nocardia sp. BMG111209].	40.86	257	142	2	36	292	35	281	2e-51	182
rs:WP_014973935	methenyltetrahydrofolate cyclohydrolase [Leuconostoc carnosum].	38.01	292	162	5	4	291	3	279	2e-51	182
rs:WP_021127711	tetrahydrofolate dehydrogenase [[Clostridium] sordellii].	36.68	289	171	5	3	290	8	285	2e-51	182
tr:A0A0C7GRR4_CLOSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.68	289	171	5	3	290	8	285	2e-51	182
tr:A0A0C7QWS1_CLOSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.68	289	171	5	3	290	8	285	2e-51	182
rs:WP_015274691	methylenetetrahydrofolate dehydrogenase [Brachyspira pilosicoli].	37.41	286	165	4	1	286	1	272	2e-51	182
rs:WP_022497489	bifunctional protein FolD, partial [Megasphaera elsdenii CAG:570].	41.46	246	129	4	49	292	1	233	2e-51	180
rs:WP_027206891	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio fibrisolvens].	38.83	291	167	4	3	292	2	282	2e-51	182
rs:WP_017187816	hypothetical protein, partial [Alkalibacillus haloalkaliphilus].	42.86	217	110	3	75	291	5	207	2e-51	179
rs:WP_030517655	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia sp. NRRL WC-3656].	39.38	259	147	2	34	292	33	281	2e-51	181
rs:WP_020760967	tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	38.36	292	171	5	5	292	4	290	2e-51	182
rs:WP_040835052	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia brevicatena].	37.80	291	171	2	1	291	1	281	3e-51	181
rs:WP_009158615	methenyltetrahydrofolate cyclohydrolase [Thalassobium sp. R2A62].	36.54	260	158	2	34	293	32	284	3e-51	182
tr:A0A0C7LVB6_CLOSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.68	289	171	5	3	290	8	285	3e-51	182
rs:WP_019179377	5,10-methylene-tetrahydrofolate dehydrogenase [Microbacterium yannicii].	39.86	296	169	6	1	292	1	291	3e-51	182
rs:WP_030248068	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptacidiphilus jeojiense].	36.05	294	174	2	1	294	1	280	3e-51	181
rs:WP_026965561	methenyltetrahydrofolate cyclohydrolase [Alicyclobacillus pomorum].	38.73	284	162	5	5	288	4	275	3e-51	182
rs:WP_039968972	5,10-methylene-tetrahydrofolate cyclohydrolase [Veillonella dispar].	36.59	276	161	3	8	283	6	267	3e-51	181
tr:G1KRM0_ANOCA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSACAP00000015529};	42.62	244	132	3	54	293	2	241	3e-51	191
rs:WP_030158427	5,10-methylene-tetrahydrofolate cyclohydrolase [Glycomyces sp. NRRL B-16210].	39.52	291	156	5	6	292	4	278	3e-51	181
rs:WP_018592155	hypothetical protein [Terrisporobacter glycolicus].	38.52	283	157	6	16	291	7	279	3e-51	181
rs:WP_022171783	MULTISPECIES: bifunctional protein FolD [Lachnospiraceae].	39.65	285	160	4	8	291	7	280	3e-51	181
rs:WP_027203144	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio fibrisolvens].	38.83	291	167	4	3	292	2	282	3e-51	181
rs:WP_022756966	tetrahydrofolate dehydrogenase [Butyrivibrio fibrisolvens].	38.83	291	167	4	3	292	2	282	3e-51	181
rs:WP_013676103	5,10-methylene-tetrahydrofolate dehydrogenase [Pseudonocardia dioxanivorans].	38.83	291	169	3	2	292	6	287	4e-51	181
tr:C4FN99_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.59	276	161	3	8	283	10	271	4e-51	181
gp:BX251412_79	FolD bifunctional protein [includes: methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] [Tropheryma whipplei TW08/27]	37.94	282	170	4	5	286	1	277	4e-51	181
rs:WP_042923090	5,10-methylene-tetrahydrofolate cyclohydrolase [Rhodococcus qingshengii].	38.46	286	162	2	1	286	21	292	4e-51	182
rs:WP_021867079	bifunctional protein FolD [Eubacterium sp. CAG:86].	36.81	288	167	5	4	290	2	275	4e-51	181
rs:WP_010354477	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces acidiscabies].	38.83	291	167	4	2	292	3	282	4e-51	181
tr:A0A0C1NLZ2_9PSEU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.59	282	160	5	6	286	18	284	4e-51	182
rs:WP_038124862	5,10-methylene-tetrahydrofolate cyclohydrolase [Veillonella sp. ICM51a].	35.25	278	166	3	6	283	4	267	4e-51	181
rs:WP_028258115	5,10-methylene-tetrahydrofolate cyclohydrolase [Veillonella montpellierensis].	37.99	279	161	3	6	284	4	270	4e-51	181
rs:WP_016671143	methenyltetrahydrofolate cyclohydrolase, partial [Yersinia pestis].	51.40	179	87	0	1	179	1	179	4e-51	177
rs:WP_028028817	methenyltetrahydrofolate cyclohydrolase [Gemmobacter nectariphilus].	36.43	291	171	4	1	291	1	277	5e-51	181
rs:WP_004134643	5,10-methylene-tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	37.16	296	171	6	5	293	4	291	5e-51	181
rs:WP_037203304	methenyltetrahydrofolate cyclohydrolase, partial [Rhizobium sp. OK494].	41.80	256	141	4	5	256	4	255	5e-51	180
rs:WP_022214499	bifunctional protein FolD [Blautia sp. CAG:237].	37.98	287	166	4	8	293	7	282	5e-51	181
rs:WP_046378636	5,10-methylene-tetrahydrofolate cyclohydrolase [Rhodococcus erythropolis].	38.81	286	161	2	1	286	16	287	5e-51	181
rs:WP_008730955	methylenetetrahydrofolate dehydrogenase [Brachyspira hampsonii].	35.64	289	172	3	5	293	4	278	5e-51	181
tr:K2AWX8_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.44	285	167	5	5	288	2	270	5e-51	181
rs:WP_020554201	methenyltetrahydrofolate cyclohydrolase [Streptomyces scabrisporus].	37.46	291	171	3	1	291	1	280	5e-51	181
rs:WP_044086703	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium bombi].	36.58	298	175	6	4	292	3	295	5e-51	181
rs:WP_033242474	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase [Actinomycetales].	37.67	292	172	2	1	292	1	282	5e-51	181
tr:X1CGR2_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S12240 {ECO:0000313|EMBL:GAG92277.1}; Flags: Fragment;	48.84	172	88	0	110	281	3	174	5e-51	177
tr:A0A078D2Z0_BRANA	SubName: Full=BnaC07g02720D protein {ECO:0000313|EMBL:CDX82594.1};	39.25	293	165	6	2	291	50	332	6e-51	182
rs:WP_046570346	methenyltetrahydrofolate cyclohydrolase [Micromonospora sp. HK10].	37.11	291	174	3	2	292	7	288	6e-51	181
rs:WP_004135959	5,10-methylene-tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	37.16	296	171	6	5	293	4	291	6e-51	181
rs:WP_047272257	5,10-methylene-tetrahydrofolate cyclohydrolase [Rhodococcus erythropolis].	38.46	286	162	2	1	286	21	292	6e-51	182
rs:WP_004635265	hypothetical protein [Dolosigranulum pigrum].	38.28	290	159	6	4	290	2	274	6e-51	181
rs:WP_040823175	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia jiangxiensis].	39.65	285	161	3	8	292	8	281	6e-51	181
rs:WP_013476775	5,10-methylene-tetrahydrofolate dehydrogenase [Micromonospora sp. L5].	37.46	291	173	3	2	292	3	284	6e-51	181
rs:WP_040768167	5,10-methylene-tetrahydrofolate cyclohydrolase [Tsukamurella sp. 1534].	39.38	259	139	3	34	292	30	270	6e-51	180
tr:W7XXM9_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GAF03205.1};	49.71	171	86	0	4	174	2	172	7e-51	177
rs:WP_007050984	methenyltetrahydrofolate cyclohydrolase [Anaerofustis stercorihominis].	38.03	284	163	4	8	290	7	278	7e-51	180
rs:WP_028476802	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia sp. CNY236].	38.76	258	148	2	33	290	32	279	7e-51	181
rs:WP_008397209	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. M62/1].	37.89	285	162	5	6	289	15	285	7e-51	181
rs:WP_021966857	bifunctional protein FolD [Clostridium sp. CAG:149].	38.16	283	160	5	8	289	6	274	7e-51	181
rs:WP_039778690	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia cerradoensis].	39.77	259	146	3	34	292	33	281	7e-51	180
tr:S6TEM7_PSESF	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EPN41592.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EPN41592.1}; Flags: Fragment;	43.66	213	116	1	1	213	1	209	8e-51	178
sp:FOLD_MYCLB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.08	284	162	5	1	284	1	273	8e-51	180
rs:WP_020384865	5,10-methylene-tetrahydrofolate dehydrogenase [Kribbella catacumbae].	38.91	257	143	2	34	290	36	278	8e-51	180
rs:WP_033154386	methenyltetrahydrofolate cyclohydrolase [Pseudobutyrivibrio ruminis].	38.28	290	168	5	3	291	2	281	8e-51	180
rs:WP_026961596	hypothetical protein [Alicyclobacillus herbarius].	38.41	289	163	8	1	288	1	275	9e-51	181
sp:FOLD_ALKMQ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.11	291	171	4	3	292	2	281	9e-51	180
rs:WP_022755478	tetrahydrofolate dehydrogenase [Butyrivibrio fibrisolvens].	38.83	291	167	4	3	292	2	282	9e-51	180
rs:WP_015842524	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus sp. JDR-2].	36.49	285	169	5	4	288	3	275	9e-51	180
tr:A0A078FYV6_BRANA	SubName: Full=BnaC03g30540D protein {ECO:0000313|EMBL:CDY17982.1};	51.67	180	81	2	114	291	116	291	1e-50	180
rs:WP_037338334	5,10-methylene-tetrahydrofolate cyclohydrolase [Amycolatopsis sp. MJM2582].	39.72	287	161	5	5	291	3	277	1e-50	180
tr:W7ZEV2_9BACI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.75	239	130	3	54	292	2	226	1e-50	178
rs:WP_012948937	methenyltetrahydrofolate cyclohydrolase [Geodermatophilus obscurus].	37.19	285	168	3	6	290	5	278	1e-50	180
rs:WP_027642185	methenyltetrahydrofolate cyclohydrolase [[Clostridium] clostridioforme].	38.31	261	150	4	33	292	28	278	1e-50	180
rs:WP_043324007	methenyltetrahydrofolate cyclohydrolase [Micromonospora sp. M42].	37.46	291	173	3	2	292	3	284	1e-50	180
rs:WP_010494634	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus elgii].	36.36	286	170	4	3	288	2	275	1e-50	180
rs:WP_030795823	methenyltetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5008].	38.28	290	168	4	2	291	3	281	1e-50	180
rs:WP_009743424	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces sp. oral taxon 178].	37.84	296	169	6	3	292	9	295	1e-50	180
rs:WP_022346696	bifunctional protein FolD [Clostridium sp. CAG:299].	38.38	284	160	5	8	290	6	275	1e-50	180
sp:FOLD_LEUMM	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	36.64	292	166	5	4	291	3	279	1e-50	180
rs:WP_019527967	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. FxanaD5].	33.90	292	179	2	2	293	6	283	1e-50	180
sp:FOLD_DICT6	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	36.46	288	171	3	5	292	4	279	1e-50	180
rs:WP_020004492	methenyltetrahydrofolate cyclohydrolase [Brachyspira innocens].	36.24	287	169	3	5	291	2	274	1e-50	179
rs:WP_030272232	methenyltetrahydrofolate cyclohydrolase [Micromonospora globosa].	37.46	291	173	3	2	292	3	284	1e-50	180
rs:WP_013113949	methenyltetrahydrofolate cyclohydrolase [Brachyspira murdochii].	35.89	287	170	3	5	291	2	274	1e-50	179
rs:WP_005376992	5,10-methylene-tetrahydrofolate dehydrogenase [Veillonella atypica].	35.25	278	166	3	6	283	4	267	1e-50	179
rs:WP_022806296	methenyltetrahydrofolate cyclohydrolase [Calescamantes bacterium JGI 0000106-H18].	38.68	287	158	8	6	288	5	277	1e-50	180
rs:WP_038152694	5,10-methylene-tetrahydrofolate cyclohydrolase [Veillonella montpellierensis].	37.99	279	161	3	6	284	4	270	1e-50	179
rs:WP_041350616	methenyltetrahydrofolate cyclohydrolase [Clostridium botulinum].	37.46	291	170	5	3	292	2	281	1e-50	179
tr:A0A0C7K4G2_CLOSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.33	289	172	5	3	290	8	285	1e-50	180
rs:WP_039824302	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia testacea].	36.99	292	174	2	1	292	1	282	2e-50	179
sp:FOLD_CLOBK	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.46	291	170	5	3	292	2	281	2e-50	179
tr:K2FCP2_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.60	285	152	7	8	288	6	271	2e-50	179
rs:WP_005161524	methylenetetrahydrofolate dehydrogenase [Amycolatopsis azurea].	39.16	286	162	5	5	290	3	276	2e-50	179
tr:A0A094KZR5_9AVES	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFZ62727.1}; Flags: Fragment;	43.70	238	126	3	60	293	1	234	2e-50	188
rs:WP_020969745	MULTISPECIES: methylenetetrahydrofolate dehydrogenase [Rhodococcus].	38.11	286	163	2	1	286	11	282	2e-50	180
rs:WP_035734790	5,10-methylene-tetrahydrofolate cyclohydrolase [Gordonia polyisoprenivorans].	40.00	260	142	2	34	293	35	280	2e-50	179
rs:WP_036089975	methenyltetrahydrofolate cyclohydrolase [Leuconostoc mesenteroides].	36.64	292	166	5	4	291	3	279	2e-50	179
tr:A0A078D5T3_BRANA	SubName: Full=BnaC07g02660D protein {ECO:0000313|EMBL:CDX82600.1}; SubName: Full=BnaC07g02730D protein {ECO:0000313|EMBL:CDX82593.1};	38.91	293	166	6	2	291	50	332	2e-50	181
rs:WP_044851899	5,10-methylene-tetrahydrofolate cyclohydrolase [Amycolatopsis orientalis].	38.81	286	163	5	5	290	3	276	2e-50	179
rs:WP_044480127	5,10-methylene-tetrahydrofolate cyclohydrolase [Rhodococcus rhodochrous].	38.11	286	163	2	1	286	16	287	2e-50	180
rs:WP_033065262	methenyltetrahydrofolate cyclohydrolase [Clostridium botulinum].	37.46	291	170	5	3	292	2	281	2e-50	179
rs:XP_001450181	hypothetical protein [Paramecium tetraurelia strain d4-2].	40.71	253	138	4	34	284	3	245	2e-50	179
rs:WP_028528961	methenyltetrahydrofolate cyclohydrolase [Ruminococcus gauvreauii].	37.85	288	167	5	8	294	7	283	2e-50	179
rs:WP_017585105	hypothetical protein [Nocardiopsis ganjiahuensis].	35.76	288	174	3	5	292	10	286	2e-50	179
rs:WP_016476493	hypothetical protein [Veillonella sp. HPA0037].	34.89	278	167	3	6	283	4	267	2e-50	179
rs:WP_009660832	5,10-methylene-tetrahydrofolate dehydrogenase [Veillonella sp. ACP1].	35.25	278	166	3	6	283	4	267	2e-50	179
rs:WP_016565154	bifunctional protein FolD [Clostridium sp. CAG:226].	38.85	260	147	3	33	292	30	277	2e-50	179
rs:WP_043141908	methenyltetrahydrofolate cyclohydrolase [Ponticoccus sp. UMTAT08].	36.79	280	167	3	15	292	13	284	2e-50	179
rs:XP_007908448	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X3 [Callorhinchus milii].	40.74	270	151	4	28	293	5	269	2e-50	188
rs:WP_021859957	bifunctional protein FolD [Dorea sp. CAG:105].	38.38	284	163	5	8	290	7	279	2e-50	179
rs:WP_041815017	5,10-methylene-tetrahydrofolate cyclohydrolase [Rhodococcus erythropolis].	38.46	286	162	2	1	286	21	292	2e-50	180
tr:M6X4F1_9LEPT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.26	242	133	2	54	295	2	229	2e-50	177
rs:XP_001729917	hypothetical protein MGL_2903 [Malassezia globosa CBS 7966].	43.85	244	127	4	54	291	2	241	2e-50	188
tr:D4IVU3_BUTFI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.93	290	169	5	3	291	2	281	3e-50	179
rs:WP_043457171	5,10-methylene-tetrahydrofolate cyclohydrolase [Gordonia polyisoprenivorans].	36.64	292	171	2	2	293	3	280	3e-50	179
sp:FOLD2_RUBXD	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.58	298	176	4	1	290	1	296	3e-50	180
rs:WP_022431464	bifunctional protein FolD [Eubacterium sp. CAG:38].	36.55	290	170	4	4	292	2	278	3e-50	179
sp:FOLD3_RUBXD	RecName: Full=Bifunctional protein FolD 3 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.58	298	176	4	1	290	1	296	3e-50	180
rs:WP_038375215	methenyltetrahydrofolate cyclohydrolase [Brachyspira alvinipulli].	35.11	282	169	3	5	286	2	269	3e-50	179
rs:WP_013231327	methenyltetrahydrofolate cyclohydrolase [Leuconostoc gelidum].	38.36	292	161	5	4	291	3	279	3e-50	179
tr:H6MTL6_GORPV	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.64	292	171	2	2	293	5	282	3e-50	179
rs:WP_044008068	methenyltetrahydrofolate cyclohydrolase [Ketogulonicigenium vulgare].	37.41	286	166	5	1	286	1	273	3e-50	179
sp:FOLD_THERP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	38.27	277	157	4	1	277	1	263	3e-50	179
tr:G9W1K2_SALET	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EHJ83866.1};	52.02	173	83	0	1	173	1	173	4e-50	176
tr:A0A093BU20_9AVES	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFV04379.1}; Flags: Fragment;	51.27	197	83	5	101	291	1	190	4e-50	176
rs:WP_037859824	methenyltetrahydrofolate cyclohydrolase, partial [Streptomyces sp. NRRL F-5065].	38.33	300	169	5	1	290	1	294	4e-50	179
rs:XP_007239769	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Astyanax mexicanus].	39.40	302	98	9	3	297	30	253	4e-50	178
rs:WP_015283445	5,10-methylene-tetrahydrofolate dehydrogenase [Aciduliprofundum sp. MAR08-339].	38.46	286	156	6	5	290	2	267	4e-50	178
tr:A0A0C7JGX1_CLOSO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.33	289	172	5	3	290	8	285	4e-50	179
rs:WP_006371513	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonia polyisoprenivorans].	40.00	260	142	2	34	293	35	280	4e-50	179
rs:WP_003944084	5,10-methylene-tetrahydrofolate dehydrogenase [Rhodococcus erythropolis].	38.11	286	163	2	1	286	21	292	4e-50	179
rs:WP_036086734	methenyltetrahydrofolate cyclohydrolase [Leuconostoc pseudomesenteroides].	36.18	293	168	5	4	292	3	280	4e-50	178
rs:WP_018832586	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora].	36.55	290	175	3	3	292	8	288	4e-50	179
rs:WP_041944912	5,10-methylene-tetrahydrofolate cyclohydrolase [Tsukamurella paurometabola].	39.23	260	144	2	34	293	25	270	4e-50	178
rs:WP_026542592	5,10-methylene-tetrahydrofolate cyclohydrolase [Arthrobacter nicotinovorans].	34.71	291	179	3	1	291	1	280	4e-50	179
rs:WP_008084861	tetrahydrofolate dehydrogenase [Aciduliprofundum boonei].	38.46	286	156	7	5	290	2	267	4e-50	178
rs:WP_017751900	hypothetical protein [Clostridium tyrobutyricum].	36.08	291	174	4	3	292	2	281	4e-50	178
rs:WP_007862794	methenyltetrahydrofolate cyclohydrolase [[Clostridium] citroniae].	35.89	287	170	5	4	289	2	275	4e-50	178
rs:WP_042166922	methenyltetrahydrofolate cyclohydrolase [Paenibacillus sp. G1].	36.97	284	167	4	5	288	4	275	4e-50	178
rs:WP_025322039	methenyltetrahydrofolate cyclohydrolase [Deferrisoma camini].	39.46	294	165	5	1	290	1	285	4e-50	179
rs:WP_037311798	5,10-methylene-tetrahydrofolate cyclohydrolase [Amycolatopsis orientalis].	38.81	286	163	5	5	290	3	276	4e-50	178
rs:WP_002588252	methenyltetrahydrofolate cyclohydrolase [Clostridium clostridioforme CAG:511].	34.47	293	178	5	1	292	1	280	4e-50	178
rs:WP_041926557	methenyltetrahydrofolate cyclohydrolase [Clostridium botulinum].	37.11	291	171	5	3	292	2	281	5e-50	178
rs:WP_014279948	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus terrae].	39.16	286	162	5	3	288	2	275	5e-50	178
rs:WP_004110747	5,10-methylene-tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	36.73	294	173	6	5	292	4	290	5e-50	179
rs:WP_004107065	5,10-methylene-tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	36.95	295	177	5	3	293	2	291	5e-50	179
rs:WP_016334478	methylenetetrahydrofolate dehydrogenase [Amycolatopsis orientalis].	39.51	286	161	5	5	290	3	276	5e-50	178
rs:WP_030520634	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia rhamnosiphila].	38.01	292	171	2	1	292	1	282	5e-50	178
rs:XP_001512558	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Ornithorhynchus anatinus].	48.73	197	66	3	101	295	10	173	5e-50	175
tr:H2Z0I3_CIOSA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAVP00000011095}; Flags: Fragment;	42.36	288	133	7	9	291	9	268	5e-50	187
rs:WP_021844735	bifunctional protein FolD [Blautia hydrogenotrophica CAG:147].	38.95	285	162	4	8	291	7	280	5e-50	178
rs:WP_039678821	hypothetical protein [Terrisporobacter othiniensis].	37.32	284	161	6	16	292	7	280	5e-50	178
rs:WP_027334057	hypothetical protein [Mycoplasma elephantis].	37.10	283	160	6	5	286	3	268	5e-50	178
rs:WP_010015813	methenyltetrahydrofolate cyclohydrolase [Leuconostoc gelidum].	38.36	292	161	5	4	291	3	279	5e-50	178
rs:WP_002590786	methylenetetrahydrofolate dehydrogenase [[Clostridium] clostridioforme].	34.83	290	175	5	4	292	2	278	5e-50	178
rs:WP_020129038	5,10-methylene-tetrahydrofolate dehydrogenase [Streptomyces sp. 303MFCol5.2].	38.62	290	167	4	2	291	3	281	5e-50	178
rs:WP_042573121	methenyltetrahydrofolate cyclohydrolase [Rhodococcus sp. MEB064].	40.07	302	156	7	1	292	1	287	5e-50	178
rs:WP_025296173	methenyltetrahydrofolate cyclohydrolase [Trueperella pyogenes].	38.36	292	171	5	5	292	2	288	6e-50	178
rs:WP_040779789	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia pneumoniae].	39.69	262	148	2	30	291	29	280	6e-50	178
rs:WP_034821431	methenyltetrahydrofolate cyclohydrolase [[Eubacterium] nodatum].	34.36	291	179	5	1	290	1	280	6e-50	178
tr:J9GHW0_9ZZZZ	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EJW99044.1}; Flags: Fragment;	50.00	200	95	2	1	200	1	195	6e-50	176
rs:WP_022859216	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium magnum].	36.43	291	176	5	5	291	4	289	6e-50	178
rs:WP_005945359	tetrahydrofolate dehydrogenase [Blautia hydrogenotrophica].	38.95	285	162	4	8	291	7	280	6e-50	178
rs:WP_044646628	methenyltetrahydrofolate cyclohydrolase [Paenibacillus terrae].	39.51	286	161	5	3	288	2	275	6e-50	178
rs:WP_045092074	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. FS41].	35.54	287	171	5	4	289	2	275	6e-50	178
tr:D5UN23_TSUPD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	39.23	260	144	2	34	293	36	281	6e-50	178
tr:A0A090MZ28_STRRB	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:CEF68209.1};	41.22	296	157	7	3	289	2	289	6e-50	187
rs:WP_003418330	methenyltetrahydrofolate cyclohydrolase [Peptoclostridium difficile].	37.72	289	168	5	3	290	8	285	6e-50	178
rs:WP_005379851	5,10-methylene-tetrahydrofolate dehydrogenase [Veillonella atypica].	37.10	248	145	2	36	283	31	267	6e-50	178
rs:WP_045730824	5,10-methylene-tetrahydrofolate cyclohydrolase [Arthrobacter chlorophenolicus].	34.97	286	175	3	6	291	9	283	6e-50	178
sp:FOLD_PEPD6	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.72	289	168	5	3	290	5	282	6e-50	178
tr:B0FBR6_ORYSI	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrogenase {ECO:0000313|EMBL:ABY55040.1}; Flags: Fragment;	41.13	248	140	2	19	264	3	246	7e-50	177
rs:WP_026323535	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	35.84	293	179	3	3	295	10	293	7e-50	179
rs:WP_021894456	bifunctional protein FolD 1 [Clostridium bolteae CAG:59].	34.83	290	175	5	4	292	2	278	7e-50	178
rs:WP_038513174	5,10-methylene-tetrahydrofolate cyclohydrolase [Amycolatopsis japonica].	39.51	286	161	5	5	290	3	276	7e-50	177
rs:WP_012738687	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Eubacterium].	37.50	288	166	5	4	290	2	276	7e-50	177
rs:WP_003432264	methenyltetrahydrofolate cyclohydrolase [Peptoclostridium difficile].	37.72	289	168	5	3	290	8	285	8e-50	178
rs:WP_034299708	hypothetical protein [Alkalibacterium sp. AK22].	38.60	285	162	4	6	289	5	277	8e-50	177
sp:FOLD_RHOCB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	34.48	290	183	3	4	293	8	290	8e-50	178
rs:WP_044535883	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Bacteroides intestinalis].	47.65	170	89	0	13	182	1	170	8e-50	174
tr:W4N8L1_9BIFI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.96	274	159	6	6	274	5	272	8e-50	179
rs:WP_007029565	methylenetetrahydrofolate dehydrogenase [Amycolatopsis decaplanina].	38.81	286	163	5	5	290	3	276	9e-50	177
rs:WP_030443510	5,10-methylene-tetrahydrofolate cyclohydrolase [Actinoplanes subtropicus].	42.21	263	141	2	28	290	23	274	9e-50	177
rs:WP_029068544	methenyltetrahydrofolate cyclohydrolase [Jonesia quinghaiensis].	39.19	296	171	5	1	292	1	291	9e-50	178
rs:WP_038260117	methenyltetrahydrofolate cyclohydrolase [[Clostridium] clostridioforme].	37.16	261	153	4	33	292	28	278	9e-50	177
rs:WP_002575914	methylenetetrahydrofolate dehydrogenase [[Clostridium] bolteae].	34.83	290	175	5	4	292	2	278	9e-50	177
rs:WP_021614850	tetrahydrofolate dehydrogenase [Actinomyces sp. oral taxon 877].	37.16	296	171	6	3	292	9	295	9e-50	178
rs:WP_012688713	methenyltetrahydrofolate cyclohydrolase [Rhodococcus opacus].	38.03	284	165	3	6	289	5	277	1e-49	178
rs:WP_023915338	methenyltetrahydrofolate cyclohydrolase [Rhodobacter capsulatus].	34.48	290	183	3	4	293	8	290	1e-49	178
rs:WP_022461835	bifunctional protein FolD [Blautia sp. CAG:37].	38.25	285	164	5	8	291	7	280	1e-49	177
rs:WP_028246866	methenyltetrahydrofolate cyclohydrolase [Pseudobutyrivibrio ruminis].	37.24	290	171	4	3	291	2	281	1e-49	177
rs:XP_011396227	Bifunctional protein FolD [Auxenochlorella protothecoides].	34.40	343	163	6	2	293	38	369	1e-49	181
rs:WP_036501964	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia aobensis].	39.38	259	147	3	34	292	33	281	1e-49	177
rs:WP_007791057	methenyltetrahydrofolate cyclohydrolase [Peptostreptococcus stomatis].	36.55	290	172	5	1	289	1	279	1e-49	177
tr:A0A093CXG8_9PSEU	SubName: Full=5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:AJK57593.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AJK57593.1}; EC=3.5.4.9 {ECO:0000313|EMBL:AJK57593.1};	39.16	286	162	5	5	290	3	276	1e-49	177
rs:WP_005868344	5,10-methylene-tetrahydrofolate dehydrogenase [Actinomyces georgiae].	37.84	296	169	6	3	292	9	295	1e-49	177
rs:WP_003505132	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Clostridiales].	37.32	276	162	4	15	289	9	274	1e-49	177
rs:WP_021383453	tetrahydrofolate dehydrogenase [Peptoclostridium difficile].	37.37	289	169	5	3	290	8	285	1e-49	177
rs:WP_005540322	methenyltetrahydrofolate cyclohydrolase [Johnsonella ignava].	37.41	286	167	5	5	289	4	278	1e-49	177
rs:WP_039272443	methenyltetrahydrofolate cyclohydrolase [Paenibacillus polymyxa].	38.70	292	167	5	3	294	2	281	1e-49	177
rs:WP_047234088	methenyltetrahydrofolate cyclohydrolase [Cellulosimicrobium funkei].	38.51	296	173	5	1	292	1	291	1e-49	177
rs:WP_009902122	methenyltetrahydrofolate cyclohydrolase [Peptoclostridium difficile].	37.72	289	168	5	3	290	8	285	1e-49	177
tr:K1YU73_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.84	285	166	4	4	288	2	272	1e-49	177
tr:E3F2J6_KETVY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.32	284	165	5	3	286	2	272	1e-49	177
rs:WP_038148936	5,10-methylene-tetrahydrofolate cyclohydrolase [Veillonella atypica].	37.10	248	145	2	36	283	31	267	1e-49	177
rs:WP_018742524	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora pacifica].	35.84	293	179	3	3	295	10	293	1e-49	178
rs:WP_004910198	methenyltetrahydrofolate cyclohydrolase [Leuconostoc pseudomesenteroides].	36.18	293	168	5	4	292	3	280	1e-49	177
rs:WP_040719685	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia veterana].	39.77	259	146	2	34	292	33	281	1e-49	177
tr:U2BIU3_CLOSY	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.32	276	162	4	15	289	13	278	1e-49	177
tr:L1PXY1_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.10	248	145	2	36	283	35	271	1e-49	177
rs:WP_025967500	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Prochlorococcus sp. scB243_498P3].	45.63	206	105	3	89	293	1	200	2e-49	175
rs:WP_009672325	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus].	37.10	283	165	4	11	293	10	279	2e-49	177
rs:WP_002568552	methenyltetrahydrofolate cyclohydrolase [[Clostridium] bolteae].	34.83	290	175	5	4	292	2	278	2e-49	177
rs:WP_025683812	methenyltetrahydrofolate cyclohydrolase [Paenibacillus sp. 1-49].	39.51	286	161	5	3	288	2	275	2e-49	177
tr:U1NQ15_ASCSU	SubName: Full=C-1-tetrahydrofolate cytoplasmic {ECO:0000313|EMBL:ERG84152.1};	43.81	299	150	8	3	291	2	292	2e-49	186
tr:G5APG3_HETGA	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:EHA98923.1};	39.59	293	143	4	3	295	37	295	2e-49	177
tr:F1KRW4_ASCSU	SubName: Full=C-1-tetrahydrofolate synthase {ECO:0000313|EMBL:ADY40618.1};	43.81	299	150	8	3	291	2	292	2e-49	186
rs:WP_016636538	tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	36.27	295	175	6	5	293	4	291	2e-49	177
tr:D2GYI7_AILME	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EFB22823.1}; Flags: Fragment;	44.65	215	111	3	83	293	5	215	2e-49	185
rs:WP_021418113	tetrahydrofolate dehydrogenase [Peptoclostridium difficile].	37.72	289	168	5	3	290	8	285	2e-49	177
rs:WP_008718769	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [unclassified Clostridiales (miscellaneous)].	35.64	289	172	5	4	291	2	277	2e-49	176
rs:WP_018813522	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora pacifica].	35.84	293	179	3	3	295	10	293	2e-49	177
rs:WP_040708092	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia takedensis].	40.07	287	161	3	6	292	6	281	2e-49	177
rs:XP_001451753	hypothetical protein [Paramecium tetraurelia strain d4-2].	39.55	268	147	5	22	284	22	279	2e-49	177
rs:WP_018722994	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora pacifica].	35.84	293	179	3	3	295	10	293	2e-49	177
rs:WP_031518731	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5123].	35.96	292	177	2	6	297	8	289	2e-49	177
rs:WP_039688549	methenyltetrahydrofolate cyclohydrolase [Coriobacteriaceae bacterium 68-1-3].	38.54	288	166	5	3	289	2	279	2e-49	176
rs:WP_022028804	bifunctional protein FolD [Clostridium sp. CAG:1219].	37.98	287	161	6	5	290	3	273	2e-49	176
rs:WP_036765467	methenyltetrahydrofolate cyclohydrolase [Peptostreptococcus sp. MV1].	36.90	290	171	4	1	289	1	279	2e-49	177
rs:WP_009279088	tetrahydrofolate dehydrogenase [Olsenella sp. oral taxon 809].	37.46	291	170	6	1	290	1	280	2e-49	176
rs:WP_004606626	methenyltetrahydrofolate cyclohydrolase [[Clostridium] scindens].	37.98	287	166	5	5	290	4	279	2e-49	176
rs:WP_038085950	methenyltetrahydrofolate cyclohydrolase [Tumebacillus flagellatus].	36.04	283	169	4	6	288	5	275	2e-49	177
rs:WP_040748549	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia transvalensis].	36.30	292	175	3	1	292	1	281	2e-49	176
rs:WP_008374807	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Coprococcus].	35.92	284	170	4	8	290	7	279	3e-49	176
sp:FOLD2_SYNWW	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	34.72	288	171	5	5	292	2	272	3e-49	176
rs:XP_006278806	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, partial [Alligator mississippiensis].	44.50	218	115	2	3	214	39	256	3e-49	176
rs:WP_040867285	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia exalbida].	41.22	262	144	2	30	291	29	280	3e-49	176
tr:K2ECJ4_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	34.26	289	174	4	4	291	3	276	3e-49	176
rs:WP_010347397	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus peoriae].	38.81	286	163	5	3	288	2	275	3e-49	176
rs:WP_008085046	tetrahydrofolate dehydrogenase [Aciduliprofundum boonei].	37.76	286	158	7	5	290	2	267	3e-49	176
rs:WP_029517626	methenyltetrahydrofolate cyclohydrolase [Paenibacillus polymyxa].	38.70	292	167	5	3	294	2	281	3e-49	176
tr:G5RRU6_SALET	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EHD06286.1};	50.54	184	88	1	1	181	1	184	3e-49	174
rs:WP_027661408	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	35.84	293	179	3	3	295	10	293	3e-49	176
rs:WP_027293936	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Robinsoniella].	37.63	287	167	5	8	293	7	282	3e-49	176
rs:WP_033085416	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia seriolae].	39.00	259	148	2	34	292	33	281	3e-49	176
tr:I1GEP6_AMPQE	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:PAC:15726889};	38.93	244	140	2	1	235	38	281	3e-49	176
tr:K2B6W9_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.87	315	169	4	3	292	2	308	3e-49	177
rs:WP_021423208	tetrahydrofolate dehydrogenase [Peptoclostridium difficile].	37.72	289	168	5	3	290	8	285	3e-49	176
rs:WP_002568853	methylenetetrahydrofolate dehydrogenase [[Clostridium] bolteae].	35.64	289	172	5	6	293	4	279	3e-49	176
rs:WP_013286356	5,10-methylene-tetrahydrofolate dehydrogenase [Micromonospora aurantiaca].	37.11	291	174	3	2	292	3	284	3e-49	176
rs:WP_023918607	methenyltetrahydrofolate cyclohydrolase [Rhodobacter capsulatus].	34.14	290	184	3	4	293	8	290	3e-49	177
rs:WP_022203423	bifunctional protein FolD [Clostridium clostridioforme CAG:132].	34.47	293	178	5	1	292	1	280	3e-49	176
tr:G5MEV1_SALET	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EHC53762.1};	52.02	173	83	0	1	173	1	173	3e-49	174
rs:WP_027649299	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	35.84	293	179	3	3	295	10	293	3e-49	177
rs:WP_022303046	bifunctional protein FolD [Firmicutes bacterium CAG:227].	37.88	293	154	5	8	291	7	280	4e-49	176
rs:WP_006941968	5,10-methylene-tetrahydrofolate dehydrogenase [Megasphaera micronuciformis].	36.65	281	165	4	5	285	4	271	4e-49	176
rs:XP_003781387	PREDICTED: LOW QUALITY PROTEIN: c-1-tetrahydrofolate synthase, cytoplasmic-like [Otolemur garnettii].	35.35	297	184	3	1	293	41	333	4e-49	186
rs:WP_028193715	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	35.84	293	179	3	3	295	8	291	4e-49	177
rs:WP_010008639	methenyltetrahydrofolate cyclohydrolase [Leuconostoc fallax].	37.07	294	164	6	3	291	2	279	4e-49	176
rs:WP_019228846	hypothetical protein [Sedimentibacter sp. B4].	36.49	285	169	5	8	291	7	280	4e-49	176
rs:WP_012914050	5,10-methylene-tetrahydrofolate dehydrogenase [Gardnerella vaginalis].	36.05	294	175	6	5	292	4	290	4e-49	176
rs:WP_030503938	methenyltetrahydrofolate cyclohydrolase [Micromonospora purpureochromogenes].	36.77	291	175	3	2	292	3	284	4e-49	176
rs:WP_018736920	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora pacifica].	35.74	291	178	3	3	293	10	291	4e-49	177
rs:WP_008712892	tetrahydrofolate dehydrogenase [Synergistes sp. 3_1_syn1].	36.08	291	174	5	4	293	3	282	4e-49	176
rs:WP_022212607	bifunctional protein FolD [Clostridium sp. CAG:265].	36.11	288	173	2	3	290	2	278	4e-49	176
rs:WP_006776307	methenyltetrahydrofolate cyclohydrolase [[Clostridium] hathewayi].	36.43	280	166	5	15	292	9	278	4e-49	176
rs:WP_033669783	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	35.84	293	179	3	3	295	6	289	4e-49	177
rs:WP_026184414	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	35.84	293	179	3	3	295	10	293	4e-49	177
tr:A5HUG7_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	48.15	216	105	4	78	292	16	225	5e-49	174
rs:WP_022869386	5,10-methylene-tetrahydrofolate dehydrogenase [Yaniella halotolerans].	35.91	298	177	5	1	292	1	290	5e-49	176
rs:WP_018219768	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora pacifica].	35.84	293	179	3	3	295	8	291	5e-49	177
rs:WP_024964039	methenyltetrahydrofolate cyclohydrolase [Trueperella pyogenes].	38.36	292	171	5	5	292	2	288	5e-49	176
tr:G5LZZ0_SALET	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EHC40347.1}; EC=1.5.1.5 {ECO:0000313|EMBL:EHC40347.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EHC40347.1};	52.02	173	83	0	1	173	1	173	5e-49	172
rs:WP_015938615	methenyltetrahydrofolate cyclohydrolase [Arthrobacter chlorophenolicus].	34.38	288	178	3	6	293	9	285	5e-49	176
rs:WP_025720698	methenyltetrahydrofolate cyclohydrolase [Paenibacillus sp. 1-18].	38.81	286	163	5	3	288	2	275	5e-49	176
rs:WP_025272047	5,10-methylene-tetrahydrofolate cyclohydrolase [Haloglycomyces albus].	36.93	287	169	5	4	290	2	276	5e-49	176
rs:WP_027657477	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	35.84	293	179	3	3	295	10	293	5e-49	176
rs:WP_022008422	bifunctional protein FolD [Firmicutes bacterium CAG:646].	38.60	285	163	4	8	291	7	280	6e-49	175
rs:WP_018756328	hypothetical protein [Paenibacillus terrigena].	34.97	286	174	5	5	290	4	277	6e-49	175
rs:WP_002572016	methylenetetrahydrofolate dehydrogenase [[Clostridium] bolteae].	34.48	290	176	5	4	292	2	278	6e-49	175
tr:Q4RT28_TETNG	SubName: Full=Chromosome 12 SCAF14999, whole genome shotgun sequence {ECO:0000313|EMBL:CAG08454.1};	45.66	219	113	2	3	215	30	248	6e-49	177
rs:WP_006308439	hypothetical protein [Facklamia languida].	35.64	289	173	4	3	290	2	278	6e-49	175
rs:WP_020635690	hypothetical protein [Amycolatopsis alba].	38.81	286	163	5	5	290	3	276	6e-49	175
rs:WP_018818785	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora pacifica].	35.84	293	179	3	3	295	10	293	6e-49	176
rs:WP_030150704	methenyltetrahydrofolate cyclohydrolase [Oerskovia turbata].	37.16	296	177	5	1	292	1	291	6e-49	176
rs:WP_029122942	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	35.49	293	180	4	3	295	10	293	6e-49	176
rs:XP_002107981	hypothetical protein TRIADDRAFT_49681 [Trichoplax adhaerens].	44.34	212	110	3	83	290	45	252	6e-49	184
rs:WP_039662094	methenyltetrahydrofolate cyclohydrolase [Trueperella pyogenes].	37.67	292	173	5	5	292	2	288	7e-49	175
rs:WP_022119426	bifunctional protein FolD [Firmicutes bacterium CAG:56].	38.46	286	164	4	8	292	7	281	7e-49	175
rs:WP_013308914	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus polymyxa].	38.70	292	167	5	3	294	2	281	7e-49	175
rs:WP_014650568	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus mucilaginosus].	36.81	288	167	3	5	292	6	278	7e-49	175
rs:WP_007038541	methenyltetrahydrofolate cyclohydrolase [[Clostridium] bolteae].	35.64	289	172	5	6	293	4	279	7e-49	175
rs:WP_013369551	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus polymyxa].	38.70	292	167	5	3	294	2	281	7e-49	175
rs:WP_017426244	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus].	38.36	292	168	5	3	294	2	281	7e-49	175
tr:A0A0D2LY67_GOSRA	SubName: Full=Gossypium raimondii chromosome 1, whole genome shotgun sequence {ECO:0000313|EMBL:KJB09237.1};	47.64	191	94	2	103	291	74	260	8e-49	174
rs:WP_021167172	bifunctional protein FolD [Sporomusa ovata].	37.72	289	170	4	3	290	2	281	8e-49	175
rs:WP_035282880	5,10-methylene-tetrahydrofolate cyclohydrolase [Actinokineospora sp. EG49].	37.15	288	169	4	3	290	2	277	8e-49	175
rs:WP_016169629	hypothetical protein [Dorea sp. 5-2].	37.41	286	167	4	5	289	4	278	8e-49	175
tr:G5PJH5_SALET	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EHC75905.1};	52.05	171	82	0	1	171	1	171	8e-49	172
rs:WP_029121740	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	35.84	293	179	3	3	295	10	293	8e-49	176
rs:WP_044037817	hypothetical protein [Clostridium sp. M2/40].	36.07	280	166	4	5	284	4	270	9e-49	175
tr:A0A059AEL4_EUCGR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KCW52288.1};	35.37	294	166	5	2	293	66	337	9e-49	176
rs:WP_028272941	5,10-methylene-tetrahydrofolate cyclohydrolase [Arthrobacter sp. UNC362MFTsu5.1].	35.04	274	167	3	1	274	1	263	9e-49	175
rs:WP_029127713	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	35.84	293	179	3	3	295	10	293	1e-48	176
tr:K1SXC7_9ZZZZ	SubName: Full=Methenyltetrahydrofolate cyclohydrolase /5,10-methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:EKC65287.1}; Flags: Fragment;	51.98	177	76	3	110	286	3	170	1e-48	171
rs:WP_019686224	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus polymyxa].	38.70	292	167	5	3	294	2	281	1e-48	175
tr:Q8W526_MAIZE	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cylcohydrolase isoform 3 {ECO:0000313|EMBL:AAL33592.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AAL33592.1}; EC=3.5.4.9 {ECO:0000313|EMBL:AAL33592.1}; Flags: Fragment;	52.76	163	71	2	118	278	2	160	1e-48	171
rs:WP_020574334	hypothetical protein [Actinopolymorpha alba].	36.77	291	169	6	3	291	2	279	1e-48	175
rs:WP_022033608	bifunctional protein FolD [Clostridium hathewayi CAG:224].	36.43	280	166	5	15	292	9	278	1e-48	174
rs:WP_022095129	bifunctional protein FolD [Collinsella sp. CAG:166].	36.30	292	175	4	3	293	2	283	1e-48	175
rs:WP_031749400	methenyltetrahydrofolate cyclohydrolase, partial [Mycobacterium tuberculosis].	43.12	218	114	3	74	291	8	215	1e-48	172
rs:WP_046496800	hypothetical protein [Syntrophomonas zehnderi].	35.62	292	168	6	4	293	2	275	1e-48	174
rs:WP_026267620	methenyltetrahydrofolate cyclohydrolase [Micromonospora sp. CNB394].	37.46	291	173	3	2	292	3	284	1e-48	174
rs:WP_006789833	5,10-methylene-tetrahydrofolate dehydrogenase [Anaeroglobus geminatus].	37.72	281	162	4	5	285	3	270	1e-48	174
tr:G5QW58_SALSE	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EHC93178.1};	52.05	171	82	0	1	171	1	171	1e-48	171
rs:WP_039814587	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia otitidiscaviarum].	40.93	259	143	2	34	292	33	281	1e-48	174
rs:WP_025617667	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	36.08	291	177	3	3	293	10	291	2e-48	175
tr:T0Z937_9ZZZZ	SubName: Full=5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EQD41553.1};	34.98	263	171	0	24	286	14	276	2e-48	174
rs:WP_013020248	methenyltetrahydrofolate cyclohydrolase [Stackebrandtia nassauensis].	39.44	284	160	5	6	289	4	275	2e-48	174
rs:WP_007428922	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus sp. Aloe-11].	38.01	292	169	5	3	294	2	281	2e-48	174
rs:WP_018724987	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora pacifica].	35.49	293	180	3	3	295	8	291	2e-48	175
rs:WP_021277462	tetrahydrofolate dehydrogenase [Bacteriovorax sp. DB6_IX].	36.60	265	153	5	34	293	32	286	2e-48	174
rs:WP_036675053	methenyltetrahydrofolate cyclohydrolase [Paenibacillus sp. MSt1].	34.97	286	174	4	3	288	2	275	2e-48	174
rs:WP_006908144	hypothetical protein [Facklamia hominis].	35.99	289	172	4	3	290	2	278	2e-48	174
tr:A0A0A8FL32_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.33	292	174	5	5	292	1	287	2e-48	174
tr:G0MW70_CAEBE	SubName: Full=CBN-DAO-3 protein {ECO:0000313|EMBL:EGT45954.1};	38.46	325	156	9	1	291	1	315	2e-48	175
rs:WP_034521437	methenyltetrahydrofolate cyclohydrolase, partial [Agrobacterium rhizogenes].	42.02	238	131	3	1	235	2	235	2e-48	172
rs:WP_005582064	bifunctional protein FolD [Clostridium ultunense].	37.72	289	168	4	3	290	2	279	2e-48	174
rs:WP_045878795	5,10-methylene-tetrahydrofolate cyclohydrolase [Frankia sp. DC12].	36.68	289	169	5	4	292	2	276	2e-48	174
tr:A0A090VYE2_9FLAO	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:GAL69770.1}; EC=1.5.1.5 {ECO:0000313|EMBL:GAL69770.1}; EC=3.5.4.9 {ECO:0000313|EMBL:GAL69770.1};	45.21	188	103	0	5	192	3	190	2e-48	171
rs:WP_026548344	5,10-methylene-tetrahydrofolate cyclohydrolase [Arthrobacter nicotinovorans].	34.02	291	181	3	1	291	1	280	2e-48	174
tr:A0A071HWV7_AGRRH	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:KEA04269.1}; Flags: Fragment;	42.02	238	131	3	1	235	5	238	2e-48	172
rs:WP_007516046	methenyltetrahydrofolate cyclohydrolase [Frankia sp. CN3].	45.35	258	130	3	33	290	32	278	2e-48	174
rs:WP_025234638	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. ASBs410].	36.93	287	167	4	6	291	4	277	2e-48	174
rs:XP_004584668	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Ochotona princeps].	44.65	215	111	3	83	293	168	378	2e-48	184
tr:W1DRQ6_KLEPN	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:CDL12088.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CDL12088.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CDL12088.1};	52.02	173	79	1	28	200	6	174	2e-48	171
rs:WP_026641606	methenyltetrahydrofolate cyclohydrolase [Bifidobacterium tsurumiense].	35.86	290	175	4	3	291	2	281	2e-48	174
tr:A0A0D2TUW7_GOSRA	SubName: Full=Gossypium raimondii chromosome 8, whole genome shotgun sequence {ECO:0000313|EMBL:KJB47085.1};	42.27	220	121	2	3	220	9	224	2e-48	172
rs:WP_018827338	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora pacifica].	35.49	293	180	3	3	295	10	293	2e-48	175
tr:A0A059BZW0_EUCGR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KCW71662.1};	39.79	289	121	5	3	290	32	268	3e-48	173
tr:S9YEB0_9CETA	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:EPY82535.1};	38.67	256	147	4	33	284	9	258	3e-48	173
tr:A0A066WKE5_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDN51125.1}; Flags: Fragment;	37.71	297	168	6	3	288	92	382	3e-48	182
rs:XP_003056547	5,10-methylene-tetrahydrofolate dehydrogenase/cyclohydrolase [Micromonas pusilla CCMP1545].	33.43	353	164	6	3	291	56	401	3e-48	177
rs:WP_011771990	methenyltetrahydrofolate cyclohydrolase [Borrelia turicatae].	38.58	254	150	3	36	288	33	281	3e-48	174
rs:WP_042227110	methenyltetrahydrofolate cyclohydrolase [Paenibacillus chitinolyticus].	37.10	283	165	4	11	293	10	279	3e-48	174
rs:WP_040193851	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. CL-6].	36.11	288	172	5	5	291	4	280	3e-48	174
sp:FOLD1_RHOJR	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	36.97	284	168	3	6	289	5	277	3e-48	174
tr:Q8W528_MAIZE	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cylcohydrolase isoform 1 {ECO:0000313|EMBL:AAL33590.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AAL33590.1}; EC=3.5.4.9 {ECO:0000313|EMBL:AAL33590.1}; Flags: Fragment;	52.15	163	72	2	118	278	2	160	4e-48	169
sp:FOLD1_ARTAT	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	33.68	291	182	3	1	291	1	280	4e-48	174
rs:WP_013046897	methenyltetrahydrofolate cyclohydrolase [Candidatus Puniceispirillum marinum].	34.71	291	183	3	3	293	5	288	4e-48	174
rs:WP_018830138	5,10-methylene-tetrahydrofolate dehydrogenase [Salinispora tropica].	36.62	284	171	3	3	286	8	282	4e-48	174
rs:WP_040808073	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia concava].	37.19	285	168	3	8	292	8	281	4e-48	173
rs:WP_038040603	methenyltetrahydrofolate cyclohydrolase, partial [Thermomicrobiales bacterium KI4].	35.09	285	167	5	1	284	1	268	4e-48	172
rs:WP_036434051	methenyltetrahydrofolate cyclohydrolase [Mycoplasma columborale].	38.38	284	160	6	4	286	2	271	4e-48	173
tr:X1TLW8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_S10087 {ECO:0000313|EMBL:GAI92361.1}; Flags: Fragment;	40.41	193	115	0	1	193	7	199	5e-48	170
rs:WP_022318989	bifunctional protein FolD [Dorea sp. CAG:317].	35.99	289	173	5	5	292	4	281	5e-48	173
rs:WP_030909836	methenyltetrahydrofolate cyclohydrolase, partial [Streptomyces sp. NRRL F-5126].	35.79	299	178	5	1	290	1	294	5e-48	173
rs:WP_024819296	5,10-methylene-tetrahydrofolate cyclohydrolase [Arthrobacter sp. 31Y].	34.15	287	178	3	5	291	17	292	5e-48	174
rs:WP_027438337	methenyltetrahydrofolate cyclohydrolase [Lachnospira multipara].	35.87	276	166	3	15	289	9	274	5e-48	173
rs:WP_023987125	MULTISPECIES: 5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus].	38.36	292	168	5	3	294	2	281	6e-48	173
rs:WP_000320084	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Acinetobacter baumannii].	38.37	245	138	4	50	293	2	234	6e-48	171
rs:WP_028925551	methenyltetrahydrofolate cyclohydrolase [Pseudonocardia acaciae].	35.74	291	178	3	2	292	11	292	6e-48	173
tr:K2NJX8_TRYCR	SubName: Full=Methylenetetrahydrofolate dehydrogenase-like protein, putative {ECO:0000313|EMBL:EKF39735.1};	34.34	332	167	6	1	288	1	325	6e-48	174
rs:WP_006235389	tetrahydrofolate dehydrogenase [Collinsella aerofaciens].	36.43	291	174	4	3	292	2	282	6e-48	173
rs:WP_024655753	methenyltetrahydrofolate cyclohydrolase [Borrelia hispanica].	38.04	255	152	3	35	288	32	281	6e-48	173
tr:W7T4B1_9PSEU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	40.17	239	139	3	1	238	1	236	6e-48	171
rs:WP_028570101	methenyltetrahydrofolate cyclohydrolase [Salinispora tropica].	36.65	281	169	3	6	286	11	282	6e-48	173
rs:WP_031557183	methenyltetrahydrofolate cyclohydrolase [Lachnospira multipara].	35.51	276	167	3	15	289	9	274	6e-48	172
rs:WP_046833882	methenyltetrahydrofolate cyclohydrolase, partial [Xanthomonas axonopodis].	50.00	178	77	3	117	292	2	169	7e-48	169
rs:WP_031462934	methenyltetrahydrofolate cyclohydrolase [Paenibacillus polymyxa].	38.01	292	169	5	3	294	2	281	7e-48	173
rs:WP_040790469	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia paucivorans].	40.68	263	146	2	29	291	29	281	7e-48	172
rs:WP_004045978	hypothetical protein, partial [Lactobacillus sp. ASF360].	46.07	191	92	3	102	292	1	180	7e-48	169
tr:K2CQ51_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.47	296	162	6	5	291	19	294	7e-48	173
rs:XP_007230443	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Astyanax mexicanus].	37.76	294	135	5	1	293	1	247	8e-48	181
sp:FOLD1_FRAAA	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.63	287	165	4	4	290	2	274	8e-48	172
tr:A0A094L904_ANTCR	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFZ60554.1}; Flags: Fragment;	44.29	219	116	2	3	215	4	222	8e-48	171
tr:A0A0D2SY98_GOSRA	SubName: Full=Gossypium raimondii chromosome 8, whole genome shotgun sequence {ECO:0000313|EMBL:KJB47086.1};	42.59	216	118	2	3	216	9	220	8e-48	171
rs:WP_026472595	methenyltetrahydrofolate cyclohydrolase [Alloscardovia omnicolens].	37.24	290	173	5	6	291	1	285	8e-48	172
rs:WP_034810649	methenyltetrahydrofolate cyclohydrolase [[Eubacterium] sulci].	38.25	285	164	4	10	291	6	281	8e-48	172
rs:WP_025406174	methenyltetrahydrofolate cyclohydrolase [Borrelia hermsii].	38.19	254	151	3	36	288	33	281	8e-48	173
rs:WP_027647130	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	36.18	293	177	4	3	295	10	292	9e-48	173
rs:WP_016819849	5,10-methylene-tetrahydrofolate dehydrogenase [Paenibacillus polymyxa].	38.01	292	169	5	3	294	2	281	9e-48	172
rs:WP_031474359	methenyltetrahydrofolate cyclohydrolase [[Clostridium] aminophilum].	35.74	291	166	7	4	290	5	278	9e-48	172
rs:WP_044888494	5,10-methylene-tetrahydrofolate cyclohydrolase [Frankia sp. CpI1-S].	37.63	287	165	4	4	290	2	274	9e-48	172
rs:WP_006555613	hypothetical protein [Veillonella ratti].	36.92	279	164	3	6	284	4	270	9e-48	172
rs:XP_009614503	PREDICTED: bifunctional protein FolD 2-like [Nicotiana tomentosiformis].	43.46	214	115	2	32	243	13	222	9e-48	174
rs:WP_036430183	methenyltetrahydrofolate cyclohydrolase [Mycoplasma felis].	40.35	285	154	8	4	286	2	272	9e-48	172
rs:WP_025349507	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia nova].	39.77	259	146	2	34	292	33	281	9e-48	172
rs:WP_019047598	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Actinomycetales].	39.69	257	145	2	36	292	35	281	1e-47	172
tr:K2CD08_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.70	292	147	9	1	286	1	266	1e-47	172
tr:U3AJ77_9RHOB	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:GAD57734.1};	42.79	229	127	1	1	229	1	225	1e-47	171
rs:WP_022424267	bifunctional protein FolD [Catenibacterium sp. CAG:290].	36.62	284	165	5	8	290	6	275	1e-47	172
tr:U1QR24_9BIFI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.59	290	172	5	6	291	44	328	1e-47	173
rs:WP_022167943	bifunctional protein FolD [Clostridium sp. CAG:221].	37.50	288	169	2	3	290	2	278	1e-47	172
rs:WP_006504319	methenyltetrahydrofolate cyclohydrolase [Catenibacterium mitsuokai].	36.62	284	165	5	8	290	6	275	1e-47	172
tr:F3CE03_PSESG	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EGH17495.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EGH17495.1}; Flags: Fragment;	43.48	207	113	1	9	215	1	203	1e-47	169
rs:WP_024654225	methenyltetrahydrofolate cyclohydrolase [Borrelia persica].	37.80	254	152	3	36	288	33	281	2e-47	172
rs:WP_025375084	methenyltetrahydrofolate cyclohydrolase [Borrelia parkeri].	37.80	254	152	3	36	288	33	281	2e-47	172
rs:WP_018653659	hypothetical protein [Actinomadura flavalba].	36.99	292	175	4	1	292	1	283	2e-47	172
gp:FR773526_1214	methylenetetrahydrofolate dehydrogenase (NADP+) [Clostridium botulinum H04402 065]	40.16	244	135	4	50	292	10	243	2e-47	170
rs:WP_044937640	methenyltetrahydrofolate cyclohydrolase [Pseudobutyrivibrio sp. LB2011].	36.55	290	173	5	3	291	2	281	2e-47	171
rs:WP_009532011	methenyltetrahydrofolate cyclohydrolase [Stomatobaculum longum].	35.99	289	171	5	6	293	4	279	2e-47	171
tr:B6XTY8_9BIFI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	42.53	221	119	4	77	293	15	231	2e-47	170
rs:WP_040893213	methenyltetrahydrofolate cyclohydrolase [[Bacteroides] pectinophilus].	34.48	290	176	5	4	292	2	278	2e-47	171
gp:CP003856_3140	5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase [Acinetobacter baumannii TYTH-1]	38.59	241	135	4	54	293	2	230	2e-47	170
rs:WP_007300403	methenyltetrahydrofolate cyclohydrolase [Rhodococcus imtechensis].	38.67	256	147	2	34	289	32	277	2e-47	172
tr:B7AQ13_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	34.48	290	176	5	4	292	8	284	2e-47	171
rs:WP_016882891	methenyltetrahydrofolate cyclohydrolase [Rhodococcus sp. DK17].	36.62	284	169	3	6	289	5	277	2e-47	172
rs:WP_030531985	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Prauserella rugosa].	36.92	279	162	4	11	289	9	273	2e-47	171
rs:WP_036450189	hypothetical protein [Mycoplasma molare].	38.52	257	140	5	31	284	31	272	2e-47	171
rs:WP_021905461	bifunctional protein FolD [Clostridium sp. CAG:81].	36.30	281	167	5	15	293	9	279	2e-47	171
tr:S8CTP5_9LAMI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPS68256.1}; Flags: Fragment;	39.92	248	134	3	3	239	72	315	2e-47	172
tr:X0X0R7_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S15387 {ECO:0000313|EMBL:GAG18596.1}; Flags: Fragment;	41.50	200	116	1	1	200	1	199	2e-47	169
rs:WP_011860048	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Acinetobacter baumannii].	38.59	241	135	4	54	293	2	230	2e-47	169
rs:WP_027645461	methenyltetrahydrofolate cyclohydrolase [Salinispora pacifica].	35.49	293	180	3	3	295	10	293	2e-47	172
rs:WP_005253978	methenyltetrahydrofolate cyclohydrolase [Rhodococcus opacus].	38.67	256	147	2	34	289	32	277	2e-47	172
tr:A0A0D8DM21_9EURY	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:KJE49731.1};	33.57	286	176	4	5	290	2	273	2e-47	171
rs:WP_022361445	bifunctional protein FolD [Bacteroides pectinophilus CAG:437].	34.48	290	176	5	4	292	2	278	2e-47	171
rs:WP_027869388	methenyltetrahydrofolate cyclohydrolase [Eubacterium sp. AB3007].	36.27	295	174	6	1	293	1	283	2e-47	171
rs:WP_046499957	hypothetical protein [Syntrophomonas zehnderi].	36.40	283	163	5	5	287	2	267	2e-47	171
rs:WP_002601149	methylenetetrahydrofolate dehydrogenase [Hungatella hathewayi].	36.10	277	165	5	15	289	9	275	3e-47	171
sp:FOLD_DESAH	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	34.95	289	179	3	3	290	2	282	3e-47	171
tr:G5RBY1_SALET	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EHC95336.1}; EC=1.5.1.5 {ECO:0000313|EMBL:EHC95336.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EHC95336.1};	51.76	170	82	0	1	170	1	170	3e-47	169
tr:G5LKA9_SALET	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EHC44084.1};	51.76	170	82	0	1	170	1	170	3e-47	169
rs:XP_008463323	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X5 [Cucumis melo].	40.24	246	137	5	2	244	94	332	3e-47	172
rs:XP_010238068	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X2 [Brachypodium distachyon].	40.59	239	136	2	3	239	88	322	3e-47	172
rs:WP_012920850	5,10-methylene-tetrahydrofolate dehydrogenase [Kribbella flavida].	35.52	290	163	5	1	290	21	286	3e-47	171
tr:A0A0D6PRC8_9PROT	SubName: Full=Bifunctional [5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase] {ECO:0000313|EMBL:GAN90217.1};	36.99	292	172	5	1	291	1	281	3e-47	171
rs:WP_026116819	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardiopsis valliformis].	40.15	259	144	2	34	292	28	275	3e-47	171
rs:WP_003777343	hypothetical protein [Alloiococcus otitis].	35.99	289	172	4	3	290	2	278	4e-47	171
rs:WP_019419559	hypothetical protein [Paenibacillus sp. OSY-SE].	34.86	284	173	4	5	288	4	275	4e-47	171
tr:K1SW59_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKC61948.1};	43.65	197	106	2	4	200	3	194	4e-47	169
rs:WP_026533448	5,10-methylene-tetrahydrofolate cyclohydrolase [Arthrobacter sp. H41].	34.67	274	168	3	1	274	1	263	4e-47	171
rs:WP_012421808	methenyltetrahydrofolate cyclohydrolase [Borrelia hermsii].	37.69	260	155	4	30	288	28	281	4e-47	171
rs:WP_009474512	methenyltetrahydrofolate cyclohydrolase [Rhodococcus sp. JVH1].	36.62	284	169	3	6	289	5	277	4e-47	171
rs:WP_025407539	methenyltetrahydrofolate cyclohydrolase [Borrelia parkeri].	37.40	254	153	3	36	288	33	281	4e-47	171
tr:W5STA8_9SPIO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.40	254	153	3	36	288	40	288	5e-47	171
rs:WP_037226752	5,10-methylene-tetrahydrofolate cyclohydrolase [Rhodococcus wratislaviensis].	38.67	256	147	2	34	289	32	277	5e-47	171
rs:WP_022487914	bifunctional protein FolD [Acidaminococcus sp. CAG:542].	35.69	283	165	4	1	283	1	266	5e-47	170
rs:WP_031163706	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptosporangium roseum].	37.11	291	171	5	1	291	1	279	5e-47	170
rs:WP_026874210	5,10-methylene-tetrahydrofolate cyclohydrolase [Jiangella gansuensis].	38.28	290	167	5	1	290	1	278	5e-47	170
rs:WP_006779051	methenyltetrahydrofolate cyclohydrolase [[Clostridium] hathewayi].	34.64	280	169	5	6	284	4	270	5e-47	170
rs:WP_020627392	methenyltetrahydrofolate cyclohydrolase [Pseudonocardia sp. P2].	36.68	289	169	4	5	293	17	291	5e-47	171
tr:A0A067HH82_CITSI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDO87306.1};	42.73	220	120	2	3	220	9	224	5e-47	169
rs:WP_025407716	methenyltetrahydrofolate cyclohydrolase [Borrelia coriaceae].	37.40	254	153	3	36	288	33	281	5e-47	171
rs:WP_029468715	methenyltetrahydrofolate cyclohydrolase [Blautia producta].	37.20	293	156	5	8	291	7	280	6e-47	170
rs:WP_043257444	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. Tu6071].	36.77	291	172	4	2	292	11	289	6e-47	171
tr:F3Z888_9ACTO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.90	290	171	4	3	292	16	293	6e-47	171
rs:WP_013054584	methenyltetrahydrofolate cyclohydrolase [Mycoplasma crocodyli].	39.37	287	153	9	4	286	2	271	6e-47	170
rs:WP_025531756	methenyltetrahydrofolate cyclohydrolase [[Clostridium] hathewayi].	36.10	277	165	5	15	289	9	275	6e-47	170
rs:WP_046431175	5,10-methylene-tetrahydrofolate cyclohydrolase [Carnobacterium sp. N15.MGS-207].	40.43	282	155	5	1	282	1	269	6e-47	170
tr:F6YTJ0_ORNAN	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOANP00000028259};	48.86	176	84	2	110	283	7	178	6e-47	167
rs:XP_010168675	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Caprimulgus carolinensis].	44.04	218	116	2	3	214	3	220	8e-47	168
rs:WP_043455644	5,10-methylene-tetrahydrofolate cyclohydrolase [Arthrobacter phenanthrenivorans].	34.46	296	183	3	1	296	1	285	8e-47	170
rs:WP_037389582	methenyltetrahydrofolate cyclohydrolase, partial [Serratia symbiotica].	49.43	176	79	2	87	262	2	167	8e-47	166
rs:WP_018597559	tetrahydrofolate dehydrogenase [Blautia producta].	37.19	285	167	4	8	291	7	280	8e-47	170
tr:B5RQK8_BORRA	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.80	254	152	3	36	288	45	293	8e-47	171
rs:WP_025444076	methenyltetrahydrofolate cyclohydrolase [Borrelia miyamotoi].	37.11	256	151	4	36	288	33	281	9e-47	170
tr:D7GUL8_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.94	281	168	5	15	293	9	279	9e-47	169
rs:WP_041178068	methenyltetrahydrofolate cyclohydrolase [Borrelia recurrentis].	37.80	254	152	3	36	288	33	281	9e-47	170
rs:WP_006011207	tetrahydrofolate dehydrogenase, partial [Ehrlichia chaffeensis].	51.10	182	80	4	110	289	6	180	1e-46	167
rs:WP_010240828	methenyltetrahydrofolate cyclohydrolase [Pseudonocardia sp. P1].	37.93	290	167	4	2	290	10	287	1e-46	170
rs:WP_007283746	methylenetetrahydrofolate dehydrogenase [Gluconobacter thailandicus].	36.99	292	172	5	1	291	1	281	1e-46	169
rs:WP_046591372	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. MUSC149T].	40.70	285	157	3	6	290	11	283	1e-46	170
rs:WP_026506224	hypothetical protein [Butyrivibrio sp. NC3005].	36.55	290	168	4	8	291	7	286	1e-46	169
rs:WP_035847241	5,10-methylene-tetrahydrofolate cyclohydrolase [Kitasatospora azatica].	34.93	292	178	4	1	292	1	280	1e-46	169
tr:A0A075I946_9ARCH	SubName: Full=Methylenetetrahydrofolate dehydrogenase (FolD) {ECO:0000313|EMBL:AIF22563.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AIF22563.1};	42.13	216	120	2	1	216	7	217	1e-46	168
rs:WP_007591771	methenyltetrahydrofolate cyclohydrolase [Lachnoanaerobaculum sp. OBRC5-5].	35.89	287	168	5	8	293	6	277	1e-46	169
rs:XP_009161976	hypothetical protein T265_00055 [Opisthorchis viverrini].	33.56	292	175	4	17	293	34	321	1e-46	171
rs:WP_004602428	tetrahydrofolate dehydrogenase [[Eubacterium] cellulosolvens].	36.08	291	174	5	3	292	2	281	1e-46	169
rs:WP_020954422	methenyltetrahydrofolate cyclohydrolase [Borrelia miyamotoi].	37.11	256	151	4	36	288	33	281	1e-46	170
tr:A0A0D5ZIN4_9MOLU	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:AKA49798.1};	38.60	285	155	7	4	284	2	270	1e-46	169
rs:WP_035137335	methenyltetrahydrofolate cyclohydrolase [Collinsella sp. 4_8_47FAA].	36.55	290	173	4	3	291	2	281	1e-46	169
rs:WP_022486773	bifunctional protein FolD [Acidaminococcus sp. CAG:542].	36.61	295	173	6	3	295	2	284	1e-46	169
rs:WP_022114690	5,10-methylene-tetrahydrofolate dehydrogenase [Clostridium sp. CAG:524].	35.76	288	158	7	5	292	3	263	1e-46	169
rs:WP_044117107	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Acinetobacter baumannii].	38.56	236	139	3	3	237	2	232	2e-46	168
rs:XP_001023250	methylene-tetrahydrofolate dehydrogenase/cyclohydrolase NADP-binding domain protein [Tetrahymena thermophila SB210].	35.23	298	158	7	5	286	30	308	2e-46	172
rs:WP_015074195	5,10-methylene-tetrahydrofolate dehydrogenase [Gluconobacter oxydans].	36.99	292	172	5	1	291	1	281	2e-46	169
rs:WP_028511778	methenyltetrahydrofolate cyclohydrolase [Ruminococcaceae bacterium AE2021].	36.46	288	171	5	8	294	6	282	2e-46	169
tr:F7EQP1_ORNAN	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOANP00000011017}; Flags: Fragment;	47.98	198	96	3	103	294	24	220	2e-46	167
rs:WP_026466154	5,10-methylene-tetrahydrofolate cyclohydrolase [Aerococcus urinaeequi].	33.45	281	176	3	6	286	4	273	2e-46	169
rs:WP_034443747	methenyltetrahydrofolate cyclohydrolase [Cloacibacillus evryensis].	36.08	291	174	5	4	293	3	282	2e-46	169
tr:J9P0P9_CANFA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCAFP00000039122}; Flags: Fragment;	40.57	281	142	8	16	291	6	266	2e-46	169
tr:A0A076EVG1_RHOOP	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.28	256	148	2	34	289	32	277	2e-46	169
rs:WP_018779501	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. 161MFSha2.1].	34.71	291	179	3	1	291	1	280	2e-46	169
rs:XP_813647	methylenetetrahydrofolate dehydrogenase-like protein [Trypanosoma cruzi strain CL Brener].	34.12	340	170	8	1	293	1	333	2e-46	171
rs:WP_021828290	MULTISPECIES: tetrahydrofolate dehydrogenase [Bacteria].	33.22	289	186	4	5	292	2	284	3e-46	169
rs:WP_034215682	methenyltetrahydrofolate cyclohydrolase [Lachnoanaerobaculum sp. MSX33].	35.64	289	169	6	8	294	6	279	3e-46	168
rs:WP_025400477	methenyltetrahydrofolate cyclohydrolase [Borrelia crocidurae].	37.80	254	152	3	36	288	33	281	3e-46	169
rs:WP_038277016	methenyltetrahydrofolate cyclohydrolase [[Clostridium] celerecrescens].	35.89	287	170	4	6	291	4	277	3e-46	168
tr:Q8W527_MAIZE	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cylcohydrolase isoform 2 {ECO:0000313|EMBL:AAL33591.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AAL33591.1}; EC=3.5.4.9 {ECO:0000313|EMBL:AAL33591.1}; Flags: Fragment;	52.15	163	72	2	118	278	2	160	3e-46	164
rs:WP_041177669	methenyltetrahydrofolate cyclohydrolase [Borrelia duttonii].	38.19	254	151	3	36	288	33	281	3e-46	169
rs:WP_038365825	methenyltetrahydrofolate cyclohydrolase [Borrelia duttonii].	38.19	254	151	3	36	288	33	281	3e-46	169
tr:F7CZ08_CALJA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCJAP00000032871};	55.09	167	68	3	131	291	1	166	3e-46	165
rs:WP_019729320	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Mycobacterium avium].	40.35	228	133	2	1	228	1	225	3e-46	166
tr:B4DY35_HUMAN	SubName: Full=cDNA FLJ55007, highly similar to Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:BAG63597.1};	55.09	167	68	3	131	291	1	166	3e-46	165
tr:B5RLN3_BORDL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.19	254	151	3	36	288	45	293	3e-46	169
tr:S6V8Y9_PSESF	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EPN64211.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EPN64211.1}; Flags: Fragment;	43.43	198	108	1	1	198	1	194	4e-46	165
tr:A0A095C954_SCHHA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KGB38773.1}; Flags: Fragment;	32.00	300	187	3	8	293	10	306	4e-46	169
rs:XP_011616923	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Takifugu rubripes].	40.89	247	133	6	3	242	24	264	4e-46	167
tr:W5SG57_9SPIO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.80	254	152	3	36	288	45	293	4e-46	169
rs:WP_005252392	methenyltetrahydrofolate cyclohydrolase [Rhodococcus opacus].	38.28	256	148	2	34	289	32	277	4e-46	168
tr:W6THW4_9SPIO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.19	254	151	3	36	288	45	293	4e-46	169
rs:XP_006429680	hypothetical protein CICLE_v10012007mg [Citrus clementina].	44.83	203	103	3	95	292	14	212	4e-46	166
rs:WP_037360633	5,10-methylene-tetrahydrofolate cyclohydrolase [Amycolatopsis orientalis].	37.54	285	167	3	5	289	4	277	4e-46	168
rs:WP_028935578	5,10-methylene-tetrahydrofolate cyclohydrolase [Pseudonocardia spinosispora].	38.11	286	166	4	6	291	11	285	4e-46	168
rs:WP_041250723	methenyltetrahydrofolate cyclohydrolase [Filifactor alocis].	34.13	293	182	4	1	293	3	284	5e-46	168
rs:WP_024735853	methenyltetrahydrofolate cyclohydrolase [Clostridiales bacterium VE202-15].	34.49	287	174	5	4	289	2	275	5e-46	167
rs:WP_007715701	methenyltetrahydrofolate cyclohydrolase [[Clostridium] asparagiforme].	34.15	287	175	5	4	289	2	275	5e-46	167
tr:V5BK74_TRYCR	SubName: Full=Methylenetetrahydrofolate dehydrogenase-like protein {ECO:0000313|EMBL:ESS64908.1};	34.12	340	170	8	1	293	1	333	5e-46	170
rs:WP_006337852	methenyltetrahydrofolate cyclohydrolase [Gordonia rhizosphera].	34.49	287	177	3	6	292	5	280	5e-46	168
tr:D6GST6_FILAD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	34.13	293	182	4	1	293	12	293	5e-46	168
rs:WP_021840605	bifunctional protein FolD [Veillonella sp. CAG:933].	35.84	279	167	3	6	284	4	270	5e-46	167
rs:WP_014695938	methenyltetrahydrofolate cyclohydrolase [Borrelia crocidurae].	37.80	254	152	3	36	288	33	281	5e-46	168
rs:WP_010690733	methenyltetrahydrofolate cyclohydrolase [Fructobacillus fructosus].	36.82	296	163	7	3	292	2	279	6e-46	167
rs:WP_012799204	tetrahydrofolate dehydrogenase [Slackia heliotrinireducens].	37.55	261	153	3	34	293	32	283	7e-46	167
tr:H3BA48_LATCH	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLACP00000018769}; Flags: Fragment;	38.31	295	169	6	3	291	3	290	7e-46	176
rs:WP_043723636	5,10-methylene-tetrahydrofolate cyclohydrolase [Kutzneria sp. 744].	37.15	288	163	6	5	291	3	273	7e-46	167
rs:WP_016897022	tetrahydrofolate dehydrogenase [Aerococcus viridans].	33.45	281	176	3	6	286	4	273	7e-46	167
rs:XP_010685760	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X2 [Beta vulgaris subsp. vulgaris].	38.33	240	142	2	2	239	70	305	7e-46	168
tr:W0FKJ7_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.33	292	172	4	3	293	2	283	8e-46	167
tr:S2Y445_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.59	290	154	7	9	293	5	272	8e-46	167
rs:WP_034274551	5,10-methylene-tetrahydrofolate cyclohydrolase [Amycolatopsis halophila].	40.08	257	144	3	34	290	41	287	8e-46	167
rs:WP_040653395	methenyltetrahydrofolate cyclohydrolase [Ruania albidiflava].	34.72	288	177	5	5	291	1	278	8e-46	167
rs:WP_026506820	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. MC2013].	34.72	288	177	4	3	289	2	279	8e-46	167
rs:WP_027120672	methenyltetrahydrofolate cyclohydrolase [Mycoplasma lipofaciens].	34.71	291	174	7	4	290	2	280	8e-46	167
rs:WP_007746577	methenyltetrahydrofolate cyclohydrolase [Oenococcus kitaharae].	34.93	292	167	6	4	289	3	277	8e-46	167
rs:WP_040235715	methenyltetrahydrofolate cyclohydrolase [Borrelia crocidurae].	37.80	254	152	3	36	288	33	281	9e-46	167
rs:WP_035102462	hypothetical protein [Coprococcus sp. HPP0074].	37.59	290	154	7	9	293	8	275	9e-46	167
tr:G4VBG1_SCHMA	SubName: Full=Putative formate-tetrahydrofolate ligase {ECO:0000313|EMBL:CCD77235.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CCD77235.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CCD77235.1}; EC=6.3.4.3 {ECO:0000313|EMBL:CCD77235.1};	32.67	300	185	3	8	293	10	306	9e-46	168
sp:FOLD2_RUEPO	RecName: Full=Bifunctional protein FolD 2 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	35.97	278	171	2	15	292	15	285	9e-46	167
rs:WP_027121579	methenyltetrahydrofolate cyclohydrolase [Mycoplasma leonicaptivi].	36.49	285	162	8	4	284	2	271	1e-45	167
tr:Q8WNU1_MACFA	SubName: Full=NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase {ECO:0000313|EMBL:BAB84029.1};	54.49	167	69	3	131	291	1	166	1e-45	164
rs:WP_017199247	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. M2012083].	33.33	288	181	3	4	291	10	286	1e-45	167
rs:WP_023153424	tetrahydrofolate dehydrogenase [Eubacterium brachy].	34.95	289	176	5	3	290	2	279	1e-45	167
rs:WP_005683676	methenyltetrahydrofolate cyclohydrolase [Mycoplasma alligatoris].	42.26	265	134	7	32	292	28	277	1e-45	167
rs:WP_030996130	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-5630].	35.86	290	174	4	3	292	12	289	1e-45	167
rs:WP_018032547	hypothetical protein, partial [crenarchaeote SCGC AAA261-F05].	40.48	210	114	2	84	293	1	199	1e-45	164
rs:XP_001540517	formate--tetrahydrofolate ligase [Histoplasma capsulatum NAm1].	38.89	252	147	3	1	249	1	248	1e-45	175
rs:WP_010503191	5,10-methylene-tetrahydrofolate dehydrogenase [Gluconobacter frateurii].	35.96	292	175	6	1	291	1	281	1e-45	167
rs:WP_026892468	methenyltetrahydrofolate cyclohydrolase [[Clostridium] aerotolerans].	36.46	277	164	5	15	289	11	277	1e-45	166
rs:WP_040016678	methenyltetrahydrofolate cyclohydrolase, partial [Xanthomonas axonopodis].	49.44	178	78	3	117	292	1	168	1e-45	163
tr:S9VH16_9TRYP	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:EPY26411.1};	52.20	159	66	2	133	291	2	150	1e-45	162
rs:WP_021870655	bifunctional protein FolD [Clostridium sp. CAG:7].	35.42	288	170	6	4	289	2	275	2e-45	166
rs:WP_028235422	methenyltetrahydrofolate cyclohydrolase [Pseudobutyrivibrio sp. MD2005].	35.74	291	176	4	3	292	2	282	2e-45	166
rs:WP_029422481	methenyltetrahydrofolate cyclohydrolase [Alicyclobacillus macrosporangiidus].	34.62	286	174	4	3	288	2	274	2e-45	166
rs:XP_005968441	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Pantholops hodgsonii].	37.76	241	137	4	54	293	2	230	2e-45	164
rs:WP_043426843	hypothetical protein, partial [Arthrobacter sp. AK-YN10].	36.77	291	173	3	1	291	1	280	2e-45	166
rs:WP_025399385	methenyltetrahydrofolate cyclohydrolase [Borrelia hermsii].	37.40	254	153	3	36	288	33	281	2e-45	166
tr:X0XVI3_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S31422 {ECO:0000313|EMBL:GAG40573.1}; Flags: Fragment;	48.54	171	87	1	121	291	1	170	2e-45	162
tr:X1JAR5_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C01090 {ECO:0000313|EMBL:GAH91806.1}; Flags: Fragment;	38.91	239	138	3	1	236	1	234	2e-45	164
rs:WP_009536618	methenyltetrahydrofolate cyclohydrolase [Oribacterium asaccharolyticum].	35.66	286	169	4	4	288	2	273	2e-45	166
rs:XP_010708158	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Meleagris gallopavo].	43.64	220	118	2	3	216	35	254	2e-45	166
rs:WP_025755492	methenyltetrahydrofolate cyclohydrolase [Mycoplasma cricetuli].	37.76	286	157	7	5	286	4	272	2e-45	166
rs:WP_033305517	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces atroolivaceus].	35.52	290	172	4	2	291	6	280	2e-45	166
tr:A0A0E1C0K3_BORHE	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:AHH13530.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AHH13530.1}; EC=3.5.4.9 {ECO:0000313|EMBL:AHH13530.1};	37.40	254	153	3	36	288	38	286	2e-45	166
rs:XP_004329265	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Tursiops truncatus].	53.29	167	71	3	131	291	1	166	3e-45	163
tr:F9PRF0_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.46	234	133	4	61	293	1	224	3e-45	164
rs:WP_042432482	methenyltetrahydrofolate cyclohydrolase [Senegalimassilia anaerobia].	34.59	292	179	4	3	293	2	282	3e-45	166
tr:X1A6X1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S03609 {ECO:0000313|EMBL:GAG77464.1}; Flags: Fragment;	42.19	192	111	0	1	192	1	192	3e-45	163
rs:WP_021932830	bifunctional protein FolD [Firmicutes bacterium CAG:124].	36.36	297	177	6	3	293	2	292	3e-45	166
rs:WP_010274813	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Streptomyces].	36.43	291	173	4	2	292	11	289	3e-45	166
rs:WP_004262332	tetrahydrofolate dehydrogenase [Aerococcus viridans].	33.45	281	176	3	6	286	4	273	3e-45	166
rs:XP_001657399	AAEL006085-PA [Aedes aegypti].	44.90	196	101	3	99	291	1	192	3e-45	173
tr:H2Q8G3_PANTR	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000010916};	36.03	297	133	5	3	293	60	305	3e-45	174
tr:D7CKH9_SYNLT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	34.11	299	178	6	1	297	1	282	3e-45	166
rs:WP_022204464	bifunctional protein FolD [Eubacterium sp. CAG:248].	35.54	287	171	5	4	289	2	275	4e-45	165
tr:F7EHB4_MACMU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000016410}; Flags: Fragment;	36.63	273	149	6	18	290	18	266	4e-45	165
rs:XP_006286721	hypothetical protein CARUB_v10002929mg [Capsella rubella].	36.52	293	169	6	3	291	56	335	4e-45	167
rs:WP_009445455	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium oral taxon 082].	34.86	284	169	5	8	290	6	274	4e-45	165
rs:WP_009662601	methenyltetrahydrofolate cyclohydrolase [Lachnoanaerobaculum sp. ICM7].	34.95	289	171	6	8	294	6	279	4e-45	165
sp:FOLD_MYCS5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	36.84	285	162	6	4	284	2	272	4e-45	165
tr:U4Q846_TEPAE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CDI40431.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CDI40431.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CDI40431.1};	48.96	192	87	4	100	290	3	184	4e-45	162
rs:WP_032008092	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Acinetobacter baumannii].	38.60	228	128	3	66	293	5	220	4e-45	163
rs:WP_033811447	methenyltetrahydrofolate cyclohydrolase, partial [Escherichia coli].	52.12	165	69	3	125	289	1	155	5e-45	161
sp:FOLD1_SACEN	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	35.40	291	177	4	2	292	11	290	6e-45	165
rs:WP_002834693	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Campylobacter coli].	48.30	176	89	2	5	179	3	177	6e-45	162
tr:T0ZE23_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EQD46386.1};	33.10	290	181	4	1	290	1	277	6e-45	165
rs:XP_005986558	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic [Latimeria chalumnae].	36.95	295	145	7	3	291	22	281	6e-45	173
rs:WP_022861382	5,10-methylene-tetrahydrofolate dehydrogenase [Bifidobacterium minimum].	38.51	296	163	8	6	292	5	290	6e-45	165
rs:WP_035792446	5,10-methylene-tetrahydrofolate cyclohydrolase [Kitasatospora mediocidica].	37.41	294	166	5	1	291	1	279	6e-45	165
sp:FOLD_THEAC	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	32.40	287	176	5	4	290	2	270	6e-45	164
rs:WP_013273867	methenyltetrahydrofolate cyclohydrolase [[Clostridium] saccharolyticum].	36.43	280	166	5	15	292	9	278	6e-45	165
tr:X1A8G7_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_C02698 {ECO:0000313|EMBL:GAG66407.1}; Flags: Fragment;	40.00	205	123	0	3	207	2	206	7e-45	162
rs:WP_022018710	bifunctional protein FolD [Firmicutes bacterium CAG:129].	35.05	291	177	4	3	292	2	281	7e-45	165
rs:WP_022206256	bifunctional protein FolD [Eubacterium sp. CAG:252].	35.54	287	171	5	4	289	2	275	7e-45	164
tr:D4M8K7_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.89	287	172	4	5	290	4	279	7e-45	165
rs:WP_030447390	5,10-methylene-tetrahydrofolate cyclohydrolase [Actinocatenispora sera].	36.81	288	166	4	5	292	1	272	8e-45	164
rs:WP_028243974	methenyltetrahydrofolate cyclohydrolase [Pseudobutyrivibrio ruminis].	36.46	288	172	4	3	289	2	279	8e-45	164
rs:WP_017889171	hypothetical protein, partial [Candidatus Caldatribacteirum californiense].	46.59	176	93	1	4	179	5	179	8e-45	161
rs:WP_033177683	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. URHA0041].	34.64	280	173	2	6	285	16	285	8e-45	165
tr:A0A0B8Q3Y3_9VIBR	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:GAM73241.1}; EC=1.5.1.5 {ECO:0000313|EMBL:GAM73241.1}; EC=3.5.4.9 {ECO:0000313|EMBL:GAM73241.1};	50.61	164	81	0	1	164	1	164	8e-45	161
tr:F7EHA4_MACMU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000016413}; Flags: Fragment;	36.26	273	145	6	18	290	14	257	8e-45	164
rs:WP_027108947	hypothetical protein [Lacticigenium naphtae].	37.59	290	167	5	3	290	2	279	8e-45	165
rs:WP_026477349	methenyltetrahydrofolate cyclohydrolase [Alkaliphilus transvaalensis].	33.92	286	177	4	6	290	5	279	8e-45	164
rs:WP_006425013	methenyltetrahydrofolate cyclohydrolase [delta proteobacterium NaphS2].	34.95	289	178	4	3	290	2	281	8e-45	164
rs:WP_021772714	tetrahydrofolate dehydrogenase [Oribacterium sp. oral taxon 078].	34.16	281	173	5	12	290	6	276	9e-45	164
tr:I3T3E6_LOTJA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AFK47038.1};	40.18	224	128	2	3	224	2	221	9e-45	163
rs:WP_022910114	5,10-methylene-tetrahydrofolate dehydrogenase [Aestuariimicrobium kwangyangense].	34.47	293	183	3	1	293	1	284	9e-45	164
rs:WP_010200433	methylenetetrahydrofolate dehydrogenase, partial [Pseudomonas amygdali].	45.02	211	111	2	1	211	1	206	9e-45	162
rs:WP_035730528	5,10-methylene-tetrahydrofolate cyclohydrolase [Frankia sp. Allo2].	37.50	296	157	7	4	292	2	276	9e-45	164
rs:WP_023840500	5,10-methylene-tetrahydrofolate dehydrogenase [Frankia sp. CcI6].	37.50	296	157	7	4	292	2	276	9e-45	164
rs:WP_006886290	methenyltetrahydrofolate cyclohydrolase [Mycoplasma anatis].	39.10	289	150	8	4	284	2	272	1e-44	164
rs:WP_028323813	methenyltetrahydrofolate cyclohydrolase [Desulfatirhabdium butyrativorans].	34.60	289	179	4	3	290	2	281	1e-44	164
rs:WP_015883473	5,10-methylene-tetrahydrofolate dehydrogenase [Beutenbergia cavernae].	33.45	293	186	3	1	293	1	284	1e-44	164
sp:FOLD_ELUMP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	34.68	297	176	4	5	293	2	288	1e-44	164
tr:S9WGB7_9TRYP	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:EPY34780.1};	48.43	159	72	2	135	293	4	152	1e-44	160
rs:WP_035318677	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. 12(A)].	35.74	277	166	5	15	289	11	277	1e-44	164
rs:WP_046901861	methenyltetrahydrofolate cyclohydrolase [Gluconobacter oxydans].	37.08	267	157	4	27	293	27	282	1e-44	164
rs:XP_007432492	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like, partial [Python bivittatus].	40.98	244	133	5	2	239	3	241	1e-44	163
rs:WP_028254883	5,10-methylene-tetrahydrofolate cyclohydrolase [Veillonella magna].	38.96	249	141	2	36	284	33	270	1e-44	164
rs:WP_044998497	methenyltetrahydrofolate cyclohydrolase [Roseburia intestinalis].	35.42	288	174	5	3	289	2	278	1e-44	164
tr:Q5IWX9_PROWI	SubName: Full=Plastid 5,10-methylene-tetrahydrofolate dehydrogenase {ECO:0000313|EMBL:AAV65369.1}; Flags: Fragment;	42.78	187	105	1	1	185	60	246	1e-44	163
rs:WP_027334945	methenyltetrahydrofolate cyclohydrolase [Mycoplasma felifaucium].	34.48	290	175	5	5	290	2	280	1e-44	164
tr:S6V8Y5_PSESF	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EPN64206.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EPN64206.1}; Flags: Fragment;	49.70	167	74	2	124	290	1	157	1e-44	160
rs:WP_023056399	tetrahydrofolate dehydrogenase [Peptoniphilus sp. BV3C26].	34.63	283	173	4	5	286	2	273	1e-44	164
gp:CP003866_26	methylenetetrahydrofolate dehydrogenase [Borrelia garinii NMJW1]	36.08	255	155	5	36	288	30	278	2e-44	164
tr:C7G6F4_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.42	288	174	5	3	289	6	282	2e-44	164
rs:WP_034449896	methenyltetrahydrofolate cyclohydrolase [Butyrivibrio sp. AE2032].	36.71	286	169	5	8	292	6	280	2e-44	164
rs:XP_003481229	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Sus scrofa].	46.33	177	95	0	3	179	37	213	2e-44	162
rs:WP_038628358	methenyltetrahydrofolate cyclohydrolase [Borrelia garinii].	36.08	255	155	5	36	288	33	281	2e-44	164
sp:FOLD_FRASN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	39.16	286	160	5	4	289	2	273	2e-44	163
rs:WP_009739481	methenyltetrahydrofolate cyclohydrolase [Frankia sp. QA3].	36.59	287	168	4	4	290	2	274	2e-44	163
rs:WP_009429830	methenyltetrahydrofolate cyclohydrolase [Oribacterium sp. oral taxon 108].	34.97	286	171	4	4	288	2	273	2e-44	163
rs:WP_020002963	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Mycoplasma].	36.49	285	163	6	4	284	2	272	2e-44	163
rs:WP_025419263	methenyltetrahydrofolate cyclohydrolase [Borrelia anserina].	36.61	254	155	3	36	288	33	281	2e-44	164
rs:WP_017007282	hypothetical protein, partial [Enterovibrio norvegicus].	42.21	199	111	1	1	199	1	195	2e-44	161
rs:WP_020073791	tetrahydrofolate dehydrogenase [[Clostridium] sporosphaeroides].	33.90	292	181	4	3	293	2	282	2e-44	163
rs:WP_027398357	methenyltetrahydrofolate cyclohydrolase [Anaerovorax odorimutans].	32.51	283	178	4	5	286	2	272	3e-44	163
rs:WP_026574937	methenyltetrahydrofolate cyclohydrolase [Bacillus sp. UNC438CL73TsuS30].	34.49	287	176	5	6	291	5	280	3e-44	163
tr:Q8BY49_MOUSE	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:BAC31133.2}; Flags: Fragment;	39.02	246	141	4	3	243	4	245	3e-44	162
rs:WP_024804748	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia sp. BMG51109].	39.62	260	147	3	33	292	32	281	3e-44	163
tr:E9RTP3_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	38.20	267	138	7	32	293	4	248	3e-44	162
rs:WP_027431886	methenyltetrahydrofolate cyclohydrolase [Lachnospira multipara].	34.98	283	170	5	8	289	6	275	3e-44	163
rs:WP_009525329	MULTISPECIES: tetrahydrofolate dehydrogenase [unclassified Peptostreptococcaceae (miscellaneous)].	35.59	281	168	5	4	283	2	270	3e-44	163
rs:WP_009214525	methenyltetrahydrofolate cyclohydrolase [Oribacterium sp. oral taxon 078].	33.81	281	174	5	12	290	6	276	3e-44	163
rs:WP_029608725	methenyltetrahydrofolate cyclohydrolase [Mycoplasma simbae].	34.92	295	174	7	4	292	2	284	3e-44	163
rs:WP_006427741	tetrahydrofolate dehydrogenase [Dorea longicatena].	33.33	288	180	5	3	289	2	278	4e-44	163
rs:WP_009065692	tetrahydrofolate dehydrogenase [Clostridium sp. MSTE9].	33.67	294	182	5	3	295	2	283	4e-44	163
rs:WP_014956695	methenyltetrahydrofolate cyclohydrolase [Desulfobacula toluolica].	34.95	289	178	4	3	290	2	281	4e-44	163
rs:WP_039454557	methenyltetrahydrofolate cyclohydrolase [Thermotoga sp. 2812B].	35.54	287	165	8	6	292	3	269	4e-44	162
rs:WP_025960545	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Prochlorococcus sp. scB245a_519E23].	44.62	195	101	3	100	293	1	189	4e-44	160
rs:WP_029512933	methenyltetrahydrofolate cyclohydrolase [Mycoplasma iners].	35.40	291	174	6	4	288	2	284	4e-44	163
rs:WP_024840436	methenyltetrahydrofolate cyclohydrolase [Cellulosimicrobium cellulans].	38.85	296	172	5	1	292	1	291	4e-44	163
rs:WP_006443718	methenyltetrahydrofolate cyclohydrolase [[Clostridium] hylemonae].	38.33	287	165	5	5	290	4	279	4e-44	163
tr:T0Z4D2_9BACT	SubName: Full=Bifunctional protein folD {ECO:0000313|EMBL:EQD23949.1};	46.15	182	88	2	105	286	1	172	4e-44	160
rs:XP_010329560	PREDICTED: LOW QUALITY PROTEIN: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Saimiri boliviensis boliviensis].	40.49	247	137	5	3	242	216	459	4e-44	167
tr:D4KYE1_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.42	288	174	5	3	289	6	282	4e-44	163
rs:WP_015561281	5,10-methylene-tetrahydrofolate dehydrogenase [Roseburia intestinalis CAG:13].	35.42	288	174	5	3	289	2	278	4e-44	162
sp:FOLD_THEMA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	35.54	287	165	8	6	292	3	269	4e-44	162
tr:E5X1F7_9BACE	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:EFV28983.1};	47.44	156	82	0	5	160	3	158	5e-44	159
rs:WP_022415838	bifunctional protein FolD [Dorea longicatena CAG:42].	33.68	288	179	5	3	289	2	278	5e-44	162
rs:WP_021888703	bifunctional protein FolD [Firmicutes bacterium CAG:110].	37.63	295	173	6	3	291	2	291	5e-44	163
rs:WP_037057937	methenyltetrahydrofolate cyclohydrolase, partial [Pseudonocardia asaccharolytica].	37.33	300	171	6	1	289	1	294	5e-44	163
sp:FOLD_THESQ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	35.19	287	166	8	6	292	3	269	5e-44	162
tr:S5DK95_9ACTN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.11	282	171	5	3	284	4	273	6e-44	162
rs:WP_014653286	methenyltetrahydrofolate cyclohydrolase [Borrelia garinii].	36.08	255	155	5	36	288	33	281	6e-44	163
sp:FOLD_THEP1	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	35.19	287	166	8	6	292	3	269	6e-44	162
rs:WP_045563714	methenyltetrahydrofolate cyclohydrolase, partial [Streptomyces sp. FxanaA7].	40.19	209	115	3	85	293	2	200	6e-44	160
tr:A0A0A9G3P5_ARUDO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:JAE17156.1};	51.57	159	73	1	135	293	5	159	7e-44	158
tr:A0A0A9E766_ARUDO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:JAD93720.1};	51.57	159	73	1	135	293	5	159	7e-44	158
rs:WP_038298775	methenyltetrahydrofolate cyclohydrolase [actinobacterium acMicro-4].	37.37	297	175	5	1	293	1	290	7e-44	162
rs:WP_033354293	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces aureofaciens].	37.11	291	171	4	1	291	1	279	7e-44	162
rs:WP_043693489	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia abscessus].	37.41	286	168	3	6	291	6	280	7e-44	162
rs:WP_006001109	tetrahydrofolate dehydrogenase [[Eubacterium] infirmum].	36.98	265	157	3	28	291	26	281	7e-44	162
rs:WP_027140722	5,10-methylene-tetrahydrofolate cyclohydrolase [Frankia sp. CN3].	37.76	286	164	5	4	289	2	273	7e-44	162
rs:WP_043652770	methenyltetrahydrofolate cyclohydrolase [Cellulosimicrobium cellulans].	38.85	296	172	5	1	292	1	291	7e-44	162
tr:A0A077ZMJ7_TRITR	SubName: Full=FTHFS and THF DHG CYH and THF DHG CYH C domain co ntaining protein {ECO:0000313|EMBL:CDW59900.1};	45.00	220	108	5	83	297	1	212	8e-44	169
rs:WP_029683824	methenyltetrahydrofolate cyclohydrolase [Thermotoga sp. A7A].	34.38	288	169	8	6	293	3	270	8e-44	162
rs:WP_041984859	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. AcH 505].	36.64	292	173	4	1	292	1	280	9e-44	162
rs:WP_028087508	methenyltetrahydrofolate cyclohydrolase [Dorea longicatena].	32.99	288	181	5	3	289	2	278	9e-44	162
rs:WP_028507525	methenyltetrahydrofolate cyclohydrolase [Ruminococcaceae bacterium AB4001].	36.24	287	171	5	8	293	6	281	1e-43	162
sp:FOLD_MYCMO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	34.63	283	168	5	5	286	3	269	1e-43	162
rs:WP_042430694	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. JCD].	33.33	294	183	5	3	295	2	283	1e-43	162
rs:WP_016410037	bifunctional protein FolD [Clostridium sp. CAG:1024].	34.69	294	179	5	3	293	2	285	1e-43	162
rs:WP_012887126	methenyltetrahydrofolate cyclohydrolase [Streptosporangium roseum].	36.08	291	174	4	1	291	1	279	1e-43	161
rs:WP_022359283	bifunctional protein FolD [Clostridium sp. CAG:43].	36.10	277	166	4	15	290	9	275	1e-43	161
tr:A0A061J2P7_TRYRA	SubName: Full=Methylenetetrahydrofolate dehydrogenase-like protein {ECO:0000313|EMBL:ESL09708.1};	33.13	335	167	7	1	288	1	325	1e-43	163
rs:WP_022370898	bifunctional protein FolD [Eggerthella sp. CAG:368].	35.27	292	171	5	2	292	7	281	1e-43	161
rs:WP_045320544	methenyltetrahydrofolate cyclohydrolase, partial [Loktanella cinnabarina].	42.61	230	128	1	6	235	12	237	1e-43	160
rs:WP_044814933	methenyltetrahydrofolate cyclohydrolase, partial [Escherichia coli].	50.90	167	72	3	91	257	1	157	1e-43	157
rs:WP_013978151	tetrahydrofolate dehydrogenase [Clostridium sp. SY8519].	34.36	291	179	4	3	292	2	281	1e-43	161
tr:C1LFF7_SCHJA	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 {ECO:0000313|EMBL:CAX73435.1}; EC=1.5.1.15 {ECO:0000313|EMBL:CAX73435.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CAX73435.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CAX73435.1}; EC=6.3.4.3 {ECO:0000313|EMBL:CAX73435.1};	32.67	303	187	4	5	293	6	305	2e-43	162
tr:K1TNV5_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKC67985.1};	59.68	124	50	0	171	294	10	133	2e-43	156
tr:Q86F84_SCHJA	SubName: Full=Clone ZZD1003 mRNA sequence {ECO:0000313|EMBL:AAP06003.1};	32.12	302	189	3	5	293	6	304	2e-43	162
rs:WP_017983409	methenyltetrahydrofolate cyclohydrolase [Amycolatopsis methanolica].	35.54	287	174	4	5	291	4	279	2e-43	161
rs:WP_037974290	methenyltetrahydrofolate cyclohydrolase [Synergistes jonesii].	33.91	289	179	5	5	292	4	281	2e-43	161
rs:WP_031489915	methenyltetrahydrofolate cyclohydrolase [Borrelia garinii].	35.69	255	156	5	36	288	33	281	2e-43	161
tr:W5KZC5_ASTMX	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAMXP00000012937};	50.88	171	76	3	126	293	10	175	2e-43	168
rs:WP_029347166	methenyltetrahydrofolate cyclohydrolase [Borrelia garinii].	36.08	255	155	5	36	288	33	281	2e-43	161
rs:WP_013424111	methenyltetrahydrofolate cyclohydrolase [Frankia sp. EuI1c].	37.37	289	167	5	4	292	2	276	2e-43	160
rs:WP_018505956	methenyltetrahydrofolate cyclohydrolase [Frankia sp. BCU110501].	38.46	286	162	5	4	289	2	273	2e-43	160
tr:B5GFW7_STRSH	SubName: Full=Methylenetetrahydrofolatedehydrogenase {ECO:0000313|EMBL:EDY45213.3}; Flags: Fragment;	37.55	237	137	3	56	292	54	279	2e-43	161
sp:FOLD_PICTO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	32.18	289	180	6	5	293	2	274	2e-43	160
tr:W5JTJ4_ANODA	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:ETN67441.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:ADAC000746-PA};	44.90	196	101	3	99	291	1	192	3e-43	168
rs:WP_031507945	methenyltetrahydrofolate cyclohydrolase [Borrelia garinii].	35.69	255	156	5	36	288	33	281	3e-43	161
rs:WP_012799595	tetrahydrofolate dehydrogenase [Slackia heliotrinireducens].	34.93	292	179	4	3	293	2	283	3e-43	160
rs:WP_014117505	tetrahydrofolate dehydrogenase [Oscillibacter valericigenes].	35.96	292	175	4	3	293	2	282	3e-43	160
rs:WP_009886319	methenyltetrahydrofolate cyclohydrolase [Ferroplasma acidarmanus].	33.91	289	177	4	5	293	2	276	3e-43	160
tr:A0A0C9R4Z2_9HYME	SubName: Full=C1TC_1 protein {ECO:0000313|EMBL:JAG72797.1}; SubName: Full=C1TC_2 protein {ECO:0000313|EMBL:JAG72795.1}; Flags: Fragment;	48.54	171	83	2	123	292	1	167	3e-43	167
rs:WP_007157845	methenyltetrahydrofolate cyclohydrolase [Oribacterium sinus].	35.21	284	170	5	8	290	6	276	3e-43	160
rs:WP_029362366	methenyltetrahydrofolate cyclohydrolase [Borrelia garinii].	35.69	255	156	5	36	288	33	281	3e-43	161
rs:WP_041433291	hypothetical protein [Syntrophothermus lipocalidus].	34.26	289	171	6	11	297	1	272	3e-43	160
rs:WP_040220966	methenyltetrahydrofolate cyclohydrolase [Collinsella sp. MS5].	35.05	291	178	4	3	292	2	282	3e-43	160
sp:FOLD_BORGA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	35.69	255	156	5	36	288	33	281	3e-43	161
rs:WP_036585085	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Paenibacillus darwinianus].	47.93	169	87	1	1	169	1	168	3e-43	157
rs:WP_022223262	bifunctional protein FolD [Firmicutes bacterium CAG:170].	36.03	297	178	6	3	293	2	292	3e-43	160
rs:WP_030736127	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces sp. NRRL F-2890].	34.28	283	175	3	4	286	3	274	4e-43	160
rs:WP_031477817	methenyltetrahydrofolate cyclohydrolase [Borrelia garinii].	35.69	255	156	5	36	288	33	281	4e-43	160
rs:WP_021630475	tetrahydrofolate dehydrogenase [Clostridium sp. ATCC BAA-442].	35.40	291	176	4	3	292	2	281	4e-43	160
rs:WP_022501325	bifunctional protein FolD [Eubacterium sp. CAG:76].	35.54	287	171	5	4	289	2	275	4e-43	160
rs:WP_038052282	methenyltetrahydrofolate cyclohydrolase [Thermotoga sp. Mc24].	34.38	288	169	8	6	293	3	270	4e-43	160
rs:WP_007495237	tetrahydrofolate dehydrogenase [Flavonifractor plautii].	35.40	291	176	4	3	292	2	281	4e-43	160
rs:WP_009218547	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae oral taxon 107].	34.18	275	167	5	17	289	11	273	4e-43	160
gp:AE016827_1852	FolD protein [Mannheimia succiniciproducens MBEL55E]	50.00	150	75	0	1	150	1	150	4e-43	156
rs:WP_006539924	methenyltetrahydrofolate cyclohydrolase [Frankia sp. EUN1f].	38.81	286	161	5	4	289	2	273	5e-43	160
rs:WP_022386427	bifunctional protein FolD [Collinsella sp. CAG:289].	35.05	291	178	4	3	292	2	282	5e-43	160
rs:WP_034655405	methenyltetrahydrofolate cyclohydrolase [Cellulosimicrobium sp. MM].	38.51	296	173	5	1	292	1	291	5e-43	160
rs:WP_038561581	methenyltetrahydrofolate cyclohydrolase [Mycoplasma californicum].	35.71	294	173	7	4	292	2	284	5e-43	160
rs:WP_022052295	bifunctional protein folD [Firmicutes bacterium CAG:631].	33.33	282	170	5	4	284	3	267	5e-43	160
rs:WP_031450380	methenyltetrahydrofolate cyclohydrolase [Desulfobacula sp. TS].	34.60	289	179	4	3	290	2	281	5e-43	160
rs:WP_006302677	tetrahydrofolate dehydrogenase [Atopobium vaginae].	34.60	289	178	5	3	290	2	280	6e-43	160
rs:WP_017867875	hypothetical protein [Lactobacillus pobuzihii].	36.21	290	169	5	3	291	2	276	6e-43	159
tr:B4FPB0_MAIZE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ACF83953.1, ECO:0000313|EnsemblPlants:GRMZM2G150485_P02};	49.69	159	76	1	135	293	5	159	6e-43	156
rs:WP_027872180	methenyltetrahydrofolate cyclohydrolase [[Eubacterium] cellulosolvens].	35.27	292	177	5	3	293	2	282	6e-43	159
sp:FOLD_THEAB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.00	273	156	7	19	291	12	268	6e-43	159
rs:WP_021482755	5,10-methylene-tetrahydrofolate dehydrogenase [Bacillus sp. EGD-AK10].	38.51	296	173	5	1	292	1	291	7e-43	160
tr:B3GUY3_SCHJA	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:ACE06913.1};	32.67	303	187	4	5	293	6	305	7e-43	161
rs:WP_010498850	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus acidipiscis].	37.86	280	159	5	3	281	2	267	7e-43	159
rs:WP_016433080	hypothetical protein [Streptomyces sp. HGB0020].	40.38	260	144	2	31	290	36	284	8e-43	160
sp:FOLD1_FRASC	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	37.50	296	157	7	4	292	2	276	8e-43	159
tr:A0A0A9SB66_ARUDO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:JAF55545.1};	51.27	158	73	1	136	293	6	159	8e-43	155
rs:WP_004103713	bifunctional protein FolD [Thermosipho africanus].	37.00	273	156	7	19	291	12	268	8e-43	159
tr:B8ZZU9_HUMAN	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000386542};	35.59	295	100	4	3	291	37	247	9e-43	159
rs:WP_043969646	methenyltetrahydrofolate cyclohydrolase [Micromonospora carbonacea].	35.74	291	178	3	3	293	11	292	9e-43	159
rs:WP_031544894	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium AC2014].	35.17	290	176	5	3	291	2	280	9e-43	159
rs:WP_043591088	5,10-methylene-tetrahydrofolate cyclohydrolase [Frankia sp. BMG5.23].	37.50	296	157	7	4	292	2	276	1e-42	159
rs:WP_044995789	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium JC7].	34.51	284	174	5	12	293	6	279	1e-42	159
rs:WP_033159963	hypothetical protein [Mycoplasma alvi].	34.21	266	154	6	34	289	19	273	1e-42	159
sp:FOLD_THEVO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	33.72	258	157	4	33	290	29	272	1e-42	159
rs:WP_042344259	methenyltetrahydrofolate cyclohydrolase [Borrelia burgdorferi].	33.22	286	181	6	5	288	4	281	1e-42	159
rs:WP_018771781	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. 162MFSha1.1].	33.79	293	183	3	1	293	1	282	1e-42	159
rs:WP_018760842	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. 135MFCol5.1].	33.79	293	183	3	1	293	1	282	1e-42	159
rs:WP_020419946	methenyltetrahydrofolate cyclohydrolase [Amycolatopsis sp. ATCC 39116].	35.19	287	175	3	5	291	4	279	1e-42	159
rs:XP_003129156	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Sus scrofa].	40.83	218	123	2	3	214	51	268	1e-42	159
gp:CP002312_25	methylenetetrahydrofolate dehydrogenase [Borrelia burgdorferi JD1]	33.22	286	181	6	5	288	11	288	1e-42	159
rs:WP_005341432	tetrahydrofolate dehydrogenase [Dorea formicigenerans].	33.33	288	180	5	3	289	2	278	2e-42	159
rs:WP_036715023	methenyltetrahydrofolate cyclohydrolase [Paenibacillus sp. P1XP2].	34.27	286	175	4	5	290	4	276	2e-42	159
rs:WP_023857948	5,10-methylene-tetrahydrofolate dehydrogenase [Parcubacteria bacterium RAAC4_OD1_1].	35.42	288	171	4	4	291	2	274	2e-42	158
tr:A0A0D2IVH6_9CHLO	SubName: Full=Strain SAG 48.87 unplaced genomic scaffold scaffold05887, whole genome shotgun sequence {ECO:0000313|EMBL:KIY91952.1};	49.06	159	77	1	135	293	5	159	2e-42	155
rs:WP_047268450	hypothetical protein [Marinitoga sp. 1197].	37.85	251	137	8	36	284	24	257	2e-42	158
rs:WP_039194313	methenyltetrahydrofolate cyclohydrolase, partial [Leisingera sp. ANG-M6].	44.55	211	113	1	1	211	1	207	2e-42	156
rs:WP_035435290	methenyltetrahydrofolate cyclohydrolase [Atopobium sp. BS2].	33.67	294	183	6	1	293	1	283	2e-42	159
rs:WP_022279743	MULTISPECIES: bifunctional protein FolD [Dorea].	33.33	288	180	5	3	289	2	278	2e-42	159
tr:X1EAB8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_C01135 {ECO:0000313|EMBL:GAH29532.1}; Flags: Fragment;	50.89	169	66	2	137	292	1	165	2e-42	155
rs:WP_029358492	methenyltetrahydrofolate cyclohydrolase [Borrelia garinii].	35.29	255	157	5	36	288	33	281	2e-42	159
tr:I1HWI8_BRADI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:BRADI3G01940.2};	45.30	181	97	1	2	180	83	263	2e-42	158
rs:WP_022874739	methenyltetrahydrofolate cyclohydrolase [Arthrobacter sp. PAO19].	35.62	292	174	6	1	291	1	279	2e-42	159
tr:F1RYX0_PIG	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSSCP00000009562};	40.57	212	120	2	11	216	1	212	2e-42	156
rs:WP_043641170	5,10-methylene-tetrahydrofolate cyclohydrolase [Nonomuraea candida].	39.00	259	148	3	32	290	25	273	2e-42	158
sp:FOLD_MYCPE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	35.21	284	168	6	5	286	2	271	2e-42	158
rs:WP_020948678	methylenetetrahydrofolate dehydrogenase [Borrelia burgdorferi].	35.29	255	157	5	36	288	33	281	2e-42	159
rs:WP_012802441	tetrahydrofolate dehydrogenase [Cryptobacterium curtum].	35.42	288	175	4	3	289	2	279	2e-42	158
sp:FOLD_ARTGO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	32.65	291	185	3	1	291	1	280	2e-42	158
tr:A0A096MTC3_PAPAN	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPANP00000003052};	40.91	220	124	2	3	216	12	231	2e-42	157
rs:WP_004792352	methenyltetrahydrofolate cyclohydrolase [Borrelia garinii].	35.04	254	159	3	36	288	33	281	3e-42	158
rs:WP_042335084	methenyltetrahydrofolate cyclohydrolase [Borrelia burgdorferi].	34.90	255	158	5	36	288	33	281	3e-42	158
rs:WP_029346833	methenyltetrahydrofolate cyclohydrolase [Borrelia garinii].	35.29	255	157	5	36	288	33	281	3e-42	158
rs:WP_022180976	bifunctional protein FolD [Firmicutes bacterium CAG:137].	35.88	301	176	6	3	294	2	294	3e-42	158
rs:WP_004024965	methylenetetrahydrofolate dehydrogenase [Mycoplasma iowae].	32.30	291	183	4	5	293	2	280	3e-42	158
rs:XP_006289088	hypothetical protein CARUB_v10002496mg [Capsella rubella].	36.64	292	148	6	3	291	56	313	3e-42	159
sp:FOLD_BORBU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	35.29	255	157	5	36	288	40	288	3e-42	158
rs:WP_005931966	tetrahydrofolate dehydrogenase [Faecalibacterium prausnitzii].	35.42	288	174	5	3	289	2	278	3e-42	157
rs:WP_027935249	5,10-methylene-tetrahydrofolate cyclohydrolase [Amycolatopsis thermoflava].	34.84	287	176	3	5	291	4	279	3e-42	157
rs:WP_047265050	hypothetical protein [Marinitoga sp. 1155].	37.45	251	138	8	36	284	24	257	3e-42	157
rs:WP_015055255	methenyltetrahydrofolate cyclohydrolase [Borrelia afzelii].	35.29	255	157	5	36	288	33	281	3e-42	158
rs:WP_021625422	tetrahydrofolate dehydrogenase [Atopobium sp. oral taxon 810].	33.90	292	182	4	3	293	2	283	4e-42	157
rs:WP_034545881	methenyltetrahydrofolate cyclohydrolase [Clostridiales bacterium S7-1-4].	34.38	288	177	5	6	292	8	284	4e-42	157
tr:S6TX26_PSESF	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EPN47713.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EPN47713.1}; Flags: Fragment;	45.23	199	104	2	1	199	1	194	4e-42	155
rs:WP_040659303	methenyltetrahydrofolate cyclohydrolase [Oscillibacter ruminantium].	34.02	291	180	4	3	292	2	281	4e-42	157
tr:C8WAB5_ATOPD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	33.89	298	182	5	1	293	1	288	4e-42	157
rs:XP_008955978	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X4 [Pan paniscus].	41.55	219	122	2	3	215	154	372	4e-42	160
tr:Z4X1V8_9ACTN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	33.22	289	182	5	6	293	10	288	4e-42	157
rs:WP_036406081	5,10-methylene-tetrahydrofolate cyclohydrolase [Microbispora rosea].	36.99	292	173	4	1	292	1	281	4e-42	158
rs:WP_040857360	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardia niigatensis].	38.22	259	150	2	34	292	33	281	4e-42	157
rs:WP_039949452	methenyltetrahydrofolate cyclohydrolase [Borrelia finlandensis].	35.29	255	157	5	36	288	33	281	5e-42	158
rs:WP_015707139	tetrahydrofolate dehydrogenase [Treponema primitia].	35.05	291	179	5	3	292	2	283	5e-42	157
rs:WP_041654238	methenyltetrahydrofolate cyclohydrolase [Atopobium parvulum].	34.01	294	182	5	1	293	1	283	5e-42	157
tr:A0A0C7CE18_9FUNG	SubName: Full=RMATCC62417_15736 protein {ECO:0000313|EMBL:CEG81546.1};	48.72	156	76	1	136	291	8	159	5e-42	156
tr:K2EZY7_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	37.40	262	147	5	33	292	27	273	5e-42	157
tr:X1RY57_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_C02528 {ECO:0000313|EMBL:GAI71851.1}; Flags: Fragment;	52.90	155	56	2	149	290	1	151	5e-42	153
rs:WP_006434141	methenyltetrahydrofolate cyclohydrolase [Borrelia spielmanii].	34.27	286	178	6	5	288	4	281	6e-42	157
rs:WP_006304056	tetrahydrofolate dehydrogenase [Atopobium vaginae].	33.45	278	173	5	18	292	12	280	6e-42	157
rs:WP_042781442	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Acinetobacter baumannii].	37.78	225	134	3	3	226	2	221	6e-42	155
rs:WP_044007464	methenyltetrahydrofolate cyclohydrolase [Borrelia burgdorferi].	35.29	255	157	5	36	288	33	281	7e-42	157
rs:WP_014297466	5,10-methylene-tetrahydrofolate dehydrogenase [Marinitoga piezophila].	34.14	290	160	9	5	290	2	264	7e-42	156
rs:WP_019789509	hypothetical protein, partial [Streptococcus sobrinus].	49.06	159	71	2	135	293	3	151	7e-42	153
rs:WP_031505608	methenyltetrahydrofolate cyclohydrolase [Borrelia garinii].	35.29	255	157	5	36	288	33	281	7e-42	157
rs:WP_014117231	tetrahydrofolate dehydrogenase [Oscillibacter valericigenes].	34.02	291	180	4	3	292	2	281	7e-42	157
tr:C0ANT7_9SPIO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.29	255	157	5	36	288	40	288	7e-42	157
tr:A0A0C9R892_9HYME	SubName: Full=C1TC_0 protein {ECO:0000313|EMBL:JAG72793.1};	50.97	155	72	1	138	292	4	154	7e-42	164
rs:XP_008265976	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Oryctolagus cuniculus].	40.37	218	124	2	3	214	42	259	7e-42	157
rs:WP_002556632	methylenetetrahydrofolate dehydrogenase [Borrelia burgdorferi].	34.90	255	158	5	36	288	33	281	7e-42	157
rs:WP_009015067	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Acidaminococcus].	30.00	280	179	3	5	284	6	268	7e-42	156
tr:E5X1F6_9BACE	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:EFV28982.1};	60.00	120	48	0	175	294	1	120	8e-42	152
tr:A0A0A0M6S7_9LACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGO32028.1};	35.89	287	161	6	5	285	28	297	8e-42	159
gp:CP002228_23	methylenetetrahydrofolate dehydrogenase [Borrelia burgdorferi N40]	35.29	255	157	5	36	288	40	288	8e-42	157
rs:WP_027426351	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium NC2004].	34.84	287	173	5	5	290	2	275	9e-42	156
rs:WP_030886448	5,10-methylene-tetrahydrofolate cyclohydrolase [Streptomyces varsoviensis].	37.45	259	152	2	34	292	33	281	9e-42	156
tr:K2G4P1_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	31.94	288	180	4	4	290	2	274	9e-42	156
sp:FOLD_THEM4	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	34.49	287	168	9	5	291	2	268	9e-42	156
tr:A0A0D2RRK0_GOSRA	SubName: Full=Gossypium raimondii chromosome 11, whole genome shotgun sequence {ECO:0000313|EMBL:KJB73357.1};	44.44	180	98	1	2	179	70	249	9e-42	156
tr:A0A0D2SSR1_GOSRA	SubName: Full=Gossypium raimondii chromosome 8, whole genome shotgun sequence {ECO:0000313|EMBL:KJB47089.1};	36.58	257	127	3	3	227	9	261	1e-41	156
rs:WP_019238657	hypothetical protein [Collinsella sp. GD3].	36.14	285	171	4	3	286	2	276	1e-41	157
rs:WP_038003175	methenyltetrahydrofolate cyclohydrolase [Thalassobacter sp. 16PALIMAR09].	34.53	278	171	2	15	292	16	282	1e-41	157
rs:WP_038954293	methenyltetrahydrofolate cyclohydrolase [Borrelia burgdorferi].	34.51	255	159	5	36	288	33	281	1e-41	157
rs:WP_043163326	methenyltetrahydrofolate cyclohydrolase [Borrelia burgdorferi].	34.90	255	158	5	36	288	33	281	1e-41	157
rs:WP_038010000	methenyltetrahydrofolate cyclohydrolase [Thalassobacter stenotrophicus].	34.89	278	170	3	15	292	16	282	1e-41	156
rs:WP_031531499	methenyltetrahydrofolate cyclohydrolase [Borrelia garinii].	35.29	255	157	5	36	288	33	281	1e-41	157
rs:WP_009534029	methenyltetrahydrofolate cyclohydrolase [Oribacterium parvum].	33.57	286	175	5	4	288	2	273	1e-41	156
tr:E4YKB9_OIKDI	SubName: Full=Whole genome shotgun assembly, allelic scaffold set, scaffold scaffoldA_423 {ECO:0000313|EMBL:CBY35930.1};	33.68	291	176	6	1	288	1	277	1e-41	157
sp:FOLD_BORBZ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	35.29	255	157	5	36	288	40	288	1e-41	157
rs:WP_029244768	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Streptococcus sobrinus].	49.37	158	70	2	136	293	1	148	1e-41	152
rs:WP_038375487	methenyltetrahydrofolate cyclohydrolase [Borrelia burgdorferi].	35.29	255	157	5	36	288	33	281	1e-41	157
rs:WP_019433480	hypothetical protein [Streptomyces sp. AA0539].	34.52	281	173	3	6	286	7	276	1e-41	156
rs:WP_038992945	5,10-methylene-tetrahydrofolate cyclohydrolase [Arthrobacter sp. W1].	34.47	293	180	4	1	293	1	281	1e-41	156
rs:WP_006492586	bifunctional protein FolD [Mesotoga infera].	35.40	291	162	9	5	291	2	270	1e-41	156
rs:WP_019773856	hypothetical protein, partial [Streptococcus sobrinus].	49.06	159	71	2	135	293	5	153	1e-41	152
rs:WP_036521778	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Nitrospina sp. AB-629-B18].	54.42	147	56	2	147	293	1	136	1e-41	152
tr:T1CD96_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP(+)) {ECO:0000313|EMBL:EQD80372.1}; Flags: Fragment;	51.77	141	64	1	75	215	3	139	1e-41	152
tr:T0XVN8_9ZZZZ	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EQD26851.1}; Flags: Fragment;	53.47	144	63	1	82	225	1	140	1e-41	152
tr:W5F0R8_WHEAT	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Traes_5AL_B772D42F0.1};	40.87	208	117	2	34	239	9	212	1e-41	154
rs:XP_007126325	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2-like [Physeter catodon].	40.00	220	126	2	3	216	51	270	1e-41	156
rs:WP_041103107	methenyltetrahydrofolate cyclohydrolase [Mycoplasma californicum].	35.37	294	174	7	4	292	2	284	2e-41	156
rs:WP_010255273	methenyltetrahydrofolate cyclohydrolase [Borrelia burgdorferi].	35.29	255	157	5	36	288	33	281	2e-41	156
rs:WP_005366386	tetrahydrofolate dehydrogenase [[Eubacterium] yurii].	33.81	281	174	5	4	283	2	271	2e-41	155
rs:WP_008751285	methenyltetrahydrofolate cyclohydrolase [Lachnoanaerobaculum saburreum].	32.40	287	178	5	8	293	6	277	2e-41	155
tr:X1DSG2_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S15718 {ECO:0000313|EMBL:GAH07914.1}; Flags: Fragment;	43.62	188	95	2	106	293	8	184	2e-41	153
sp:FOLD_MYCA5	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	36.01	286	164	7	5	288	4	272	2e-41	156
rs:WP_022146269	bifunctional protein FolD [Firmicutes bacterium CAG:238].	34.60	289	176	5	4	289	2	280	2e-41	156
rs:WP_009082095	tetrahydrofolate dehydrogenase [Peptostreptococcaceae bacterium AS15].	33.81	281	174	5	4	283	2	271	2e-41	155
rs:WP_014730632	methenyltetrahydrofolate cyclohydrolase [Mesotoga prima].	37.81	283	152	8	5	284	2	263	2e-41	155
rs:XP_006059706	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Bubalus bubalis].	40.83	218	123	2	3	214	51	268	2e-41	156
rs:WP_040288676	methenyltetrahydrofolate cyclohydrolase [Alicyclobacillus hesperidum].	33.10	284	178	4	3	286	2	273	2e-41	155
tr:G2RRA2_BACME	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP(+)) {ECO:0000313|EMBL:AEN90038.1};	52.60	154	62	3	137	290	7	149	2e-41	152
rs:XP_006289805	hypothetical protein CARUB_v10003409mg [Capsella rubella].	33.22	289	181	3	5	291	2	280	2e-41	155
rs:WP_021735361	tetrahydrofolate dehydrogenase [Coriobacteriaceae bacterium BV3Ac1].	34.59	292	180	4	3	293	2	283	3e-41	155
rs:WP_019213748	hypothetical protein [Clostridiales bacterium 9401234].	32.53	289	183	4	4	291	3	280	3e-41	155
rs:WP_036729418	methenyltetrahydrofolate cyclohydrolase [Peptoniphilus sp. ChDC B134].	35.14	259	157	4	34	291	28	276	3e-41	155
rs:XP_004312893	PREDICTED: LOW QUALITY PROTEIN: c-1-tetrahydrofolate synthase, cytoplasmic [Tursiops truncatus].	34.78	299	161	6	5	293	26	300	3e-41	163
rs:WP_022395830	bifunctional protein FolD [Coprobacillus sp. CAG:826].	39.62	265	130	9	34	293	25	264	3e-41	154
rs:WP_027123752	hypothetical protein [Mycoplasma pirum].	32.43	259	159	3	31	286	23	268	3e-41	155
rs:XP_008311930	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Cynoglossus semilaevis].	41.03	234	127	5	3	230	22	250	4e-41	154
rs:WP_035431663	methenyltetrahydrofolate cyclohydrolase [Atopobium parvulum].	32.08	293	188	4	2	293	6	288	4e-41	155
rs:WP_018963335	hypothetical protein [Coprothermobacter platensis].	40.67	209	114	2	78	286	66	264	4e-41	154
tr:E4Z645_OIKDI	SubName: Full=Whole genome shotgun assembly, allelic scaffold set, scaffold scaffoldA_3642 {ECO:0000313|EMBL:CBY43173.1}; Flags: Fragment;	32.65	291	179	5	1	288	1	277	4e-41	155
tr:J9IAB8_9SPIT	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:EJY75179.1};	38.86	211	118	4	22	227	20	224	5e-41	154
rs:WP_032985080	methenyltetrahydrofolate cyclohydrolase [Borrelia garinii].	35.66	258	152	6	36	288	33	281	5e-41	155
rs:WP_029513828	methenyltetrahydrofolate cyclohydrolase [Mycoplasma primatum].	32.76	290	179	5	5	290	3	280	5e-41	154
rs:WP_014023286	methenyltetrahydrofolate cyclohydrolase [Borrelia bissettii].	34.90	255	158	5	36	288	33	281	5e-41	155
rs:WP_004790434	methenyltetrahydrofolate cyclohydrolase [Borrelia afzelii].	35.29	255	157	5	36	288	33	281	5e-41	155
tr:E4WVD4_OIKDI	SubName: Full=Whole genome shotgun assembly, reference scaffold set, scaffold scaffold_3 {ECO:0000313|EMBL:CBY21087.1};	33.33	291	177	6	1	288	1	277	5e-41	155
rs:WP_006068327	methenyltetrahydrofolate cyclohydrolase [Borrelia valaisiana].	35.04	254	159	4	36	288	33	281	6e-41	155
rs:WP_038954447	methenyltetrahydrofolate cyclohydrolase [Borrelia burgdorferi].	34.90	255	158	5	36	288	33	281	6e-41	155
rs:WP_036606642	methenyltetrahydrofolate cyclohydrolase, partial [Oribacterium sp. P6A1].	34.16	281	173	5	12	290	6	276	6e-41	154
rs:WP_025957793	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Prochlorococcus sp. scB245a_518J7].	40.80	174	103	0	6	179	5	178	6e-41	151
sp:FOLD_BORAP	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	35.29	255	157	5	36	288	33	281	6e-41	155
tr:A0A068X865_HYMMI	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:CDS28306.1};	33.22	304	179	6	3	292	2	295	6e-41	155
rs:WP_005941997	tetrahydrofolate dehydrogenase [Faecalibacterium prausnitzii].	36.21	290	173	5	3	291	2	280	7e-41	154
tr:W1W6U4_9FIRM	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:ETJ12064.1}; Flags: Fragment;	40.96	188	100	2	96	283	1	177	7e-41	151
rs:WP_002295960	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Streptococcus mutans].	53.74	147	58	3	145	291	1	137	7e-41	150
rs:XP_007997078	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X5 [Chlorocebus sabaeus].	40.83	218	123	2	3	214	51	268	7e-41	154
rs:WP_008754893	methenyltetrahydrofolate cyclohydrolase [Lachnoanaerobaculum saburreum].	32.75	287	177	5	8	293	6	277	7e-41	154
rs:WP_010256444	tetrahydrofolate dehydrogenase [Treponema primitia].	34.26	289	178	4	3	290	2	279	8e-41	154
rs:WP_042750896	methenyltetrahydrofolate cyclohydrolase, partial [Lactobacillus brevis].	48.57	175	78	4	114	286	2	166	8e-41	151
rs:WP_029200580	methenyltetrahydrofolate cyclohydrolase [Oribacterium sp. NK2B42].	34.88	281	171	5	12	290	6	276	8e-41	154
gp:CP009212_25	methenyltetrahydrofolate cyclohydrolase [Borrelia afzelii Tom3107]	35.29	255	157	5	36	288	40	288	9e-41	154
tr:F0G1I5_9BURK	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EGD04648.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EGD04648.1}; Flags: Fragment;	47.70	174	90	1	1	174	1	173	9e-41	150
tr:W9TGG1_9PSED	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EXF47245.1};	49.36	156	69	2	135	290	1	146	9e-41	150
tr:V6Q5A7_9ENTE	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	33.11	293	181	5	1	292	1	279	9e-41	154
rs:WP_020617901	hypothetical protein [Paenibacillus daejeonensis].	34.97	286	174	4	5	290	4	277	9e-41	154
rs:WP_035428768	methenyltetrahydrofolate cyclohydrolase [Atopobium sp. ICM42b].	32.99	294	185	6	1	293	1	283	9e-41	154
rs:WP_038351867	methylenetetrahydrofolate dehydrogenase [Eubacterium limosum].	35.56	270	162	5	1	263	1	265	9e-41	154
rs:WP_031549546	methenyltetrahydrofolate cyclohydrolase [Oribacterium sp. FC2011].	34.88	281	171	5	12	290	6	276	9e-41	154
rs:WP_040015554	methenyltetrahydrofolate cyclohydrolase [Dorea formicigenerans].	32.64	288	182	5	3	289	2	278	1e-40	154
rs:XP_007648858	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1 [Cricetulus griseus].	41.43	210	117	2	11	214	1	210	1e-40	152
rs:WP_047120404	5,10-methylene-tetrahydrofolate cyclohydrolase [Arthrobacter sp. YC-RL1].	33.94	274	170	3	1	274	1	263	1e-40	154
rs:WP_019125585	tetrahydrofolate dehydrogenase [Peptoniphilus grossensis].	35.58	267	157	5	21	286	20	272	1e-40	154
tr:B0G7G6_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	32.64	288	182	5	3	289	9	285	1e-40	154
rs:WP_010667682	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Acetobacter aceti].	50.94	159	71	3	138	296	5	156	1e-40	150
rs:WP_009221943	methenyltetrahydrofolate cyclohydrolase [Peptoniphilus sp. oral taxon 386].	34.75	259	158	4	34	291	28	276	1e-40	154
rs:WP_009297451	hypothetical protein [Clostridium sp. 7_3_54FAA].	33.67	294	181	5	3	293	2	284	1e-40	154
tr:W4LXL0_9DELT	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:ETX02491.1}; EC=1.5.1.5 {ECO:0000313|EMBL:ETX02491.1}; EC=3.5.4.9 {ECO:0000313|EMBL:ETX02491.1}; Flags: Fragment;	33.62	235	155	1	1	235	1	234	1e-40	152
rs:WP_037671928	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Streptomyces griseus].	40.10	202	107	2	92	293	7	194	1e-40	151
rs:WP_005885774	5,10-methylene-tetrahydrofolate dehydrogenase [Brevibacterium mcbrellneri].	37.41	294	175	5	4	293	3	291	1e-40	154
rs:WP_028843866	methenyltetrahydrofolate cyclohydrolase [Pseudothermotoga elfii].	35.97	278	159	8	5	282	2	260	1e-40	153
rs:WP_026975266	methenyltetrahydrofolate cyclohydrolase [Alicyclobacillus contaminans].	35.69	283	170	4	6	288	5	275	1e-40	154
tr:Z4X3I8_9ACTN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	32.55	298	186	6	1	293	1	288	1e-40	154
tr:F7EHF9_MACMU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000016408}; Flags: Fragment;	33.68	285	157	5	6	290	5	257	1e-40	153
rs:WP_013378713	methylenetetrahydrofolate dehydrogenase [Eubacterium limosum].	35.56	270	162	5	1	263	1	265	1e-40	154
rs:WP_039122727	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Lactobacillus ruminis].	41.94	186	105	2	4	189	3	185	2e-40	150
rs:NP_001031508	amino acid dehydrogenase family protein [Arabidopsis thaliana].	42.70	178	100	1	5	180	65	242	2e-40	152
rs:XP_004283632	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Orcinus orca].	39.91	218	125	2	3	214	51	268	2e-40	152
rs:XP_011979066	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X3 [Ovis aries musimon].	60.14	138	48	3	160	291	166	302	2e-40	154
rs:XP_011979066	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform X3 [Ovis aries musimon].	50.00	100	50	0	3	102	65	164	2e-17	90.5
tr:E9CPB8_9ENTR	SubName: Full=Putative bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EFW11324.1}; Flags: Fragment;	46.99	166	78	2	97	262	1	156	2e-40	149
rs:XP_004572885	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Maylandia zebra].	51.70	147	67	1	147	293	1	143	2e-40	149
sp:FOLD_FERNB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	35.16	273	162	6	21	293	14	271	2e-40	152
rs:WP_019128224	hypothetical protein [Enorma massiliensis].	34.36	291	180	4	3	292	2	282	2e-40	153
tr:K4RNR9_HELHE	SubName: Full=Helicobacter heilmanii ASB1.4 main chromosome, draft genome {ECO:0000313|EMBL:CCM73649.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CCM73649.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CCM73649.1};	50.00	144	61	2	147	290	1	133	2e-40	148
rs:WP_032356507	methenyltetrahydrofolate cyclohydrolase, partial [Shigella flexneri].	51.97	152	63	3	138	289	1	142	2e-40	149
rs:WP_028975560	methenyltetrahydrofolate cyclohydrolase [Sporolactobacillus terrae].	32.52	286	180	4	3	288	2	274	2e-40	153
rs:WP_038100395	hypothetical protein [Vagococcus lutrae].	33.22	289	178	5	5	292	7	281	3e-40	152
rs:WP_021794211	hypothetical protein [Thermoplasmatales archaeon A-plasma].	33.11	293	175	8	1	291	1	274	3e-40	152
rs:WP_026311542	5,10-methylene-tetrahydrofolate cyclohydrolase [Frankia sp. BMG5.12].	37.06	286	166	5	4	289	2	273	3e-40	152
tr:A0A0A7UUV3_9SPIO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	36.19	257	152	7	36	288	33	281	3e-40	153
rs:WP_026418391	5,10-methylene-tetrahydrofolate cyclohydrolase [Actinoalloteichus cyanogriseus].	36.46	288	171	4	5	292	4	279	3e-40	152
rs:WP_013954591	methenyltetrahydrofolate cyclohydrolase [Mycoplasma bovis].	34.27	286	169	7	5	284	3	275	4e-40	152
rs:XP_010509159	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X2 [Camelina sativa].	42.70	178	100	1	5	180	66	243	4e-40	151
rs:WP_013456164	methenyltetrahydrofolate cyclohydrolase [Mycoplasma bovis].	34.27	286	169	7	5	284	3	275	4e-40	152
rs:WP_010014636	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus coryniformis].	35.15	293	165	7	4	289	2	276	5e-40	152
rs:XP_010505512	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X2 [Camelina sativa].	42.70	178	100	1	5	180	65	242	5e-40	151
rs:WP_003497226	hypothetical protein [[Clostridium] symbiosum].	33.33	294	182	5	3	293	2	284	5e-40	152
tr:E4KNJ2_9LACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	32.28	285	182	3	4	288	3	276	6e-40	152
rs:WP_024345407	methenyltetrahydrofolate cyclohydrolase [[Clostridium] methoxybenzovorans].	36.49	285	167	5	6	289	4	275	6e-40	152
rs:WP_010010873	5,10-methylene-tetrahydrofolate dehydrogenase [Lactobacillus coryniformis].	34.81	293	166	7	4	289	2	276	6e-40	152
rs:XP_012515325	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Propithecus coquereli].	44.88	205	95	4	89	287	2	194	6e-40	149
rs:WP_013354429	methenyltetrahydrofolate cyclohydrolase [Mycoplasma fermentans].	34.97	286	168	7	4	284	2	274	6e-40	152
tr:X1S7C1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_L05659 {ECO:0000313|EMBL:GAI74971.1};	59.02	122	49	1	165	286	1	121	6e-40	147
rs:WP_002295958	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Streptococcus mutans].	53.06	147	59	2	145	291	1	137	7e-40	147
tr:J2Z7Q4_9LACO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	34.81	293	166	7	4	289	3	277	7e-40	152
rs:WP_034434702	hypothetical protein [Clostridiales bacterium S5-A14a].	32.75	287	180	4	8	292	4	279	8e-40	151
rs:WP_043439566	5,10-methylene-tetrahydrofolate cyclohydrolase [Arthrobacter sp. UNC362MFTsu5.1].	32.73	275	174	3	3	277	4	267	9e-40	151
rs:XP_011530283	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Homo sapiens].	40.83	218	123	2	3	214	154	371	9e-40	154
rs:WP_013271845	methenyltetrahydrofolate cyclohydrolase [[Clostridium] saccharolyticum].	35.98	264	157	4	6	268	5	257	1e-39	151
tr:C4XED5_MYCFP	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	34.97	286	168	7	4	284	15	287	1e-39	151
rs:WP_029906485	methenyltetrahydrofolate cyclohydrolase [Mycoplasma opalescens].	34.62	286	166	7	5	284	3	273	1e-39	151
tr:A0A0D2R6Q9_GOSRA	SubName: Full=Gossypium raimondii chromosome 8, whole genome shotgun sequence {ECO:0000313|EMBL:KJB47088.1};	49.68	157	72	2	140	293	37	189	1e-39	148
rs:XP_008808390	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X2 [Phoenix dactylifera].	43.33	180	100	1	2	179	69	248	1e-39	151
rs:XP_008808390	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X2 [Phoenix dactylifera].	60.38	53	21	0	239	291	248	300	4e-10	69.3
rs:XP_009141752	PREDICTED: bifunctional protein FolD 1, mitochondrial isoform X3 [Brassica rapa].	42.78	180	97	3	5	180	65	242	1e-39	150
rs:XP_010357317	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Rhinopithecus roxellana].	40.48	210	119	2	11	214	1	210	1e-39	149
rs:WP_032112055	methenyltetrahydrofolate cyclohydrolase [bacterium OL-1].	34.95	289	177	4	6	293	1	279	1e-39	150
rs:WP_027121713	hypothetical protein [Mycoplasma moatsii].	33.68	288	160	7	5	286	3	265	1e-39	150
tr:D4K5P9_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.17	290	176	5	3	291	2	280	2e-39	150
rs:XP_007275340	c-1-tetrahydrofolate synthase [Colletotrichum gloeosporioides Nara gc5].	36.15	296	147	4	1	293	1	257	2e-39	158
tr:K2ESL7_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.52	290	155	8	3	288	2	263	2e-39	150
tr:A0A0D5ZH04_9ARCH	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AKA49061.1};	29.72	286	189	3	5	290	2	275	2e-39	150
rs:WP_020018515	hypothetical protein [Microgenomates bacterium SCGC AAA011-J08].	31.72	290	166	5	5	294	3	260	2e-39	150
rs:WP_022060773	bifunctional protein FolD [Corallococcus sp. CAG:1435].	34.14	290	171	7	3	292	2	271	2e-39	150
rs:WP_001699479	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Salmonella enterica].	52.45	143	68	0	1	143	1	143	2e-39	146
rs:WP_021643649	tetrahydrofolate dehydrogenase [[Clostridium] symbiosum].	32.99	294	183	5	3	293	2	284	3e-39	150
rs:WP_007283743	methylenetetrahydrofolate dehydrogenase [Gluconobacter thailandicus].	35.83	254	149	4	34	285	30	271	3e-39	150
rs:WP_005926775	tetrahydrofolate dehydrogenase [Faecalibacterium prausnitzii].	34.83	290	177	5	3	291	2	280	3e-39	150
rs:WP_013980903	tetrahydrofolate dehydrogenase [Eggerthella sp. YY7918].	34.26	289	178	4	3	290	2	279	4e-39	150
tr:W6KLY9_9TRYP	SubName: Full=Genomic scaffold, scaffold_6 {ECO:0000313|EMBL:CCW61922.1};	33.43	341	158	7	15	290	19	355	5e-39	152
rs:WP_003506550	hypothetical protein [[Clostridium] symbiosum].	32.99	294	183	5	3	293	2	284	5e-39	149
rs:WP_021676543	tetrahydrofolate dehydrogenase [Peptostreptococcaceae bacterium oral taxon 113].	32.88	292	180	6	4	292	3	281	5e-39	149
rs:WP_009527030	MULTISPECIES: tetrahydrofolate dehydrogenase [unclassified Peptostreptococcaceae (miscellaneous)].	33.57	280	173	5	5	283	3	270	5e-39	149
rs:WP_045088120	methenyltetrahydrofolate cyclohydrolase [Defluviitoga tunisiensis].	34.93	272	159	5	18	289	11	264	5e-39	149
tr:A0A0D6MP90_9PROT	SubName: Full=Protein folD 2 {ECO:0000313|EMBL:GAN55494.1};	34.27	286	177	4	1	286	1	275	5e-39	149
tr:A0A0B0HQL7_9BACL	SubName: Full=Bifunctional protein FolD protein {ECO:0000313|EMBL:KHF32503.1};	52.74	146	59	3	146	291	1	136	5e-39	145
rs:WP_000300967	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Leptospira interrogans].	39.90	198	105	2	98	295	1	184	6e-39	146
rs:WP_041077346	methenyltetrahydrofolate cyclohydrolase [Thermotoga caldifontis].	34.48	261	155	6	31	291	23	267	6e-39	149
rs:WP_024293909	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Lachnoclostridium].	36.14	285	168	5	6	289	4	275	6e-39	149
rs:WP_044116119	methenyltetrahydrofolate cyclohydrolase, partial [Aggregatibacter actinomycetemcomitans].	52.45	143	57	2	149	291	1	132	6e-39	145
sp:FOLD_THELT	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	35.61	278	160	8	5	282	2	260	6e-39	149
rs:XP_008059815	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Tarsius syrichta].	39.81	211	121	2	11	215	1	211	6e-39	148
rs:WP_013021800	methenyltetrahydrofolate cyclohydrolase [Mycoplasma agalactiae].	34.25	292	173	7	5	290	3	281	7e-39	149
rs:WP_033989006	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas aeruginosa].	47.33	150	79	0	1	150	1	150	7e-39	145
rs:WP_040807971	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [gamma proteobacterium IMCC1989].	36.87	217	132	2	1	216	1	213	7e-39	147
rs:WP_021726251	tetrahydrofolate dehydrogenase [Olsenella profusa].	36.15	260	156	3	34	292	32	282	7e-39	149
rs:WP_033969840	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas aeruginosa].	47.33	150	79	0	1	150	1	150	7e-39	145
rs:WP_015539456	5,10-methylene-tetrahydrofolate dehydrogenase [Gordonibacter pamelaeae].	33.33	288	174	5	3	286	2	275	7e-39	149
tr:X1F8L5_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_C02494 {ECO:0000313|EMBL:GAH28905.1}; Flags: Fragment;	35.62	219	133	3	1	216	1	214	8e-39	147
rs:WP_035140080	hypothetical protein, partial [Fischerella sp. PCC 9605].	32.63	285	177	5	6	288	3	274	8e-39	149
rs:WP_021900789	bifunctional protein FolD [Eggerthella sp. CAG:1427].	34.83	290	177	4	5	293	4	282	8e-39	149
rs:WP_021787219	hypothetical protein [Ferroplasma sp. Type II].	33.79	290	170	6	5	290	4	275	9e-39	149
tr:H2KPH8_CLOSI	SubName: Full=C1-THF synthase {ECO:0000313|EMBL:GAA31982.2};	32.18	289	163	5	17	293	34	301	9e-39	150
rs:WP_010025698	5,10-methylene-tetrahydrofolate dehydrogenase [Sporolactobacillus inulinus].	31.14	289	184	6	3	290	2	276	9e-39	149
tr:F3LJV2_9GAMM	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:EGG92831.1}; Flags: Fragment;	36.87	217	132	2	1	216	12	224	1e-38	147
tr:A0A0D6PPU3_9PROT	SubName: Full=Bifunctional [5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase] {ECO:0000313|EMBL:GAN90214.1};	38.42	203	116	2	83	285	78	271	1e-38	149
rs:WP_035910643	5,10-methylene-tetrahydrofolate cyclohydrolase [Frankia sp. CeD].	36.15	296	161	7	4	292	2	276	1e-38	148
rs:WP_024049296	bifunctional protein FolD [Negativicoccus succinicivorans].	36.01	286	170	4	6	291	4	276	1e-38	148
tr:A0A099VMJ1_9HELI	SubName: Full=5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:KGL34052.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KGL34052.1}; EC=3.5.4.9 {ECO:0000313|EMBL:KGL34052.1}; Flags: Fragment;	49.33	150	66	3	142	291	4	143	1e-38	144
rs:WP_035642096	methenyltetrahydrofolate cyclohydrolase [Lachnospiraceae bacterium FE2018].	33.45	293	177	6	3	291	2	280	1e-38	148
tr:X0V8E3_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S24145 {ECO:0000313|EMBL:GAG14419.1}; Flags: Fragment;	44.00	150	84	0	1	150	1	150	1e-38	144
tr:B9K850_THENN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	33.45	287	171	7	6	292	16	282	2e-38	148
tr:J5MRL2_PASMD	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EJS85467.1}; Flags: Fragment;	50.38	131	65	0	1	131	1	131	2e-38	143
tr:K9KFM5_HORSE	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2-like protein {ECO:0000313|EMBL:AEQ00217.1}; Flags: Fragment;	57.89	133	49	3	168	294	2	133	2e-38	143
rs:WP_012693688	methenyltetrahydrofolate cyclohydrolase [Deinococcus deserti].	34.36	291	169	9	6	290	13	287	2e-38	148
rs:WP_027341044	5,10-methylene-tetrahydrofolate cyclohydrolase [Hamadaea tsunoensis].	34.49	287	170	6	4	290	2	270	2e-38	147
rs:WP_038067341	methenyltetrahydrofolate cyclohydrolase [Thermotoga neapolitana].	33.45	287	171	7	6	292	3	269	2e-38	147
tr:K2FYE6_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.00	260	151	6	34	292	28	270	2e-38	147
tr:G3ZEE1_AGGAC	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:EGY69352.1};	53.62	138	53	2	154	291	5	131	2e-38	143
tr:W4P9H8_9BACE	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:GAE16402.1};	57.76	116	49	0	179	294	1	116	2e-38	143
rs:WP_004024316	methenyltetrahydrofolate cyclohydrolase [Mycoplasma agalactiae].	33.33	291	177	6	5	290	3	281	2e-38	147
rs:WP_002563434	MULTISPECIES: hypothetical protein [Atopobium].	32.30	291	186	4	4	293	3	283	2e-38	147
rs:WP_033119589	methenyltetrahydrofolate cyclohydrolase [Oscillibacter sp. ER4].	32.99	291	183	4	3	292	2	281	2e-38	147
rs:WP_015074197	methylenetetrahydrofolate dehydrogenase [Gluconobacter oxydans].	35.43	254	150	4	34	285	30	271	3e-38	147
rs:WP_008194467	methylenetetrahydrofolate dehydrogenase, partial [Thermotoga sp. EMP].	36.82	220	127	5	73	292	11	218	3e-38	145
rs:WP_021378697	tetrahydrofolate dehydrogenase, partial [Peptoclostridium difficile].	36.44	236	144	3	3	237	8	238	3e-38	146
rs:WP_011949318	methenyltetrahydrofolate cyclohydrolase [Mycoplasma agalactiae].	33.90	292	174	7	5	290	3	281	3e-38	147
rs:WP_022155730	bifunctional protein FolD [Firmicutes bacterium CAG:145].	34.95	289	174	6	4	289	2	279	3e-38	147
rs:WP_014355322	methylenetetrahydrofolate dehydrogenase [Acetobacterium woodii].	33.70	270	167	5	1	263	1	265	3e-38	147
rs:WP_019809225	hypothetical protein, partial [Saccharomonospora halophila].	37.44	211	129	2	1	211	1	208	3e-38	145
rs:WP_041844242	methenyltetrahydrofolate cyclohydrolase [Thermotoga sp. RQ7].	33.45	287	171	7	6	292	3	269	4e-38	147
tr:L9JNU4_TUPCH	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:ELW52008.1};	56.52	138	53	3	163	294	2	138	4e-38	142
rs:XP_011895833	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X5 [Cercocebus atys].	39.90	208	119	2	3	204	51	258	4e-38	147
rs:WP_014127834	methenyltetrahydrofolate cyclohydrolase [Thermoproteus tenax].	33.01	306	175	9	3	289	2	296	5e-38	147
tr:V7FKH8_9RHIZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESX80596.1};	41.84	196	110	1	5	200	2	193	5e-38	145
rs:WP_019108301	tetrahydrofolate dehydrogenase [Peptoniphilus senegalensis].	32.04	284	178	4	4	286	3	272	5e-38	146
tr:E6Q4V5_9ZZZZ	SubName: Full=Bifunctional protein folD {ECO:0000313|EMBL:CBI02216.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CBI02216.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CBI02216.1};	33.45	296	179	7	1	292	5	286	6e-38	147
rs:WP_026395787	methylenetetrahydrofolate dehydrogenase [Acetobacterium dehalogenans].	34.07	270	166	5	1	263	1	265	6e-38	147
rs:WP_007440671	methylenetetrahydrofolate dehydrogenase [Candidatus Arthromitus sp. SFB-2].	39.67	184	107	1	36	219	35	214	6e-38	144
rs:WP_026212607	5,10-methylene-tetrahydrofolate cyclohydrolase [Longispora albida].	35.63	261	155	4	31	290	20	268	6e-38	146
tr:W7YFI4_9BACT	SubName: Full=Bifunctional protein FolD protein {ECO:0000313|EMBL:GAF03206.1};	55.83	120	53	0	175	294	1	120	7e-38	141
tr:K1SG84_9ZZZZ	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:EKC54449.1}; Flags: Fragment;	50.66	152	66	3	135	286	5	147	8e-38	142
rs:WP_040755858	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Vitreoscilla stercoraria].	34.94	249	150	5	6	254	3	239	8e-38	146
rs:WP_046771926	5,10-methylene-tetrahydrofolate cyclohydrolase [Jiangella alkaliphila].	35.92	284	170	4	1	284	1	272	8e-38	146
rs:WP_046901864	methylenetetrahydrofolate dehydrogenase [Gluconobacter oxydans].	31.71	287	182	4	5	289	4	278	9e-38	146
rs:WP_018659611	hypothetical protein [Allofustis seminis].	34.62	286	170	7	4	286	5	276	9e-38	146
gp:CP007339_336	methylenetetrahydrofolate dehydrogenase [Salmonella enterica subsp. enterica serovar Enteritidis str.]	50.32	155	77	0	1	155	1	155	1e-37	142
rs:WP_030425475	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Acinetobacter baumannii].	37.16	218	124	4	54	270	2	207	1e-37	144
rs:WP_033192258	methenyltetrahydrofolate cyclohydrolase [Fervidobacterium islandicum].	33.45	278	170	6	13	290	6	268	1e-37	145
rs:WP_034517019	methenyltetrahydrofolate cyclohydrolase, partial [Agrobacterium rhizogenes].	50.97	155	70	3	140	292	7	157	1e-37	142
rs:XP_004696489	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Echinops telfairi].	64.29	112	37	2	186	295	108	218	1e-37	144
rs:XP_004696489	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Echinops telfairi].	47.83	115	55	1	3	117	8	117	6e-23	104
tr:B0FZN3_SHEEP	SubName: Full=Mitochondrial bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:ABY68604.1}; Flags: Fragment;	66.67	108	33	2	186	291	3	109	2e-37	140
rs:WP_019112365	hypothetical protein, partial [Verrucomicrobia bacterium SCGC AAA164-O14].	55.04	129	56	1	162	290	1	127	2e-37	140
rs:XP_009809565	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like, partial [Gavia stellata].	37.50	232	136	4	13	239	27	254	2e-37	144
rs:WP_009245447	hypothetical protein [Lachnospiraceae bacterium 2_1_58FAA].	34.57	269	150	8	31	294	27	274	2e-37	145
rs:WP_006608792	methenyltetrahydrofolate cyclohydrolase [Mycoplasma columbinum].	35.05	291	166	9	13	293	8	285	2e-37	145
rs:WP_001700158	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Salmonella enterica].	53.10	145	58	3	145	289	2	136	2e-37	141
rs:WP_042957725	hypothetical protein, partial [Enterococcus faecium].	35.09	285	171	6	8	290	7	279	2e-37	145
rs:WP_034522688	methenyltetrahydrofolate cyclohydrolase, partial [Agrobacterium rhizogenes].	50.32	155	71	3	140	292	7	157	2e-37	142
rs:XP_008493753	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Calypte anna].	64.29	112	37	2	186	295	127	237	2e-37	144
rs:XP_008493753	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Calypte anna].	45.22	115	58	1	3	117	27	136	5e-21	99.8
rs:WP_025728661	hypothetical protein [Atopobacter phocae].	32.03	281	178	5	6	286	5	272	2e-37	145
rs:WP_013932838	methenyltetrahydrofolate cyclohydrolase [Pseudothermotoga thermarum].	35.25	278	161	8	5	282	2	260	3e-37	144
rs:WP_020254696	hypothetical protein [Parcubacteria bacterium SCGC AAA040-L21].	34.03	288	162	8	5	291	2	262	3e-37	144
tr:D4VWR3_ENTFC	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.09	285	171	6	8	290	7	279	3e-37	145
rs:XP_002192019	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Taeniopygia guttata].	39.71	204	123	0	3	206	50	253	3e-37	144
rs:XP_011627203	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X2 [Amborella trichopoda].	40.78	179	104	1	3	179	80	258	3e-37	145
rs:XP_011627203	PREDICTED: bifunctional protein FolD 4, chloroplastic isoform X2 [Amborella trichopoda].	62.26	53	20	0	239	291	258	310	4e-12	74.7
rs:WP_004419359	methylenetetrahydrofolate dehydrogenase [Mycoplasma bovigenitalium].	33.22	292	178	6	4	290	2	281	3e-37	144
rs:WP_024053966	bifunctional protein FolD, partial [Streptococcus parasanguinis].	52.00	150	62	3	144	293	1	140	4e-37	140
rs:WP_036454912	hypothetical protein, partial [Mycoplasma hyosynoviae].	33.68	288	168	9	4	286	3	272	4e-37	144
tr:A0A063YF83_9MOLU	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:KDE45238.1}; Flags: Fragment;	33.68	288	168	9	4	286	3	272	5e-37	144
rs:WP_036445447	hypothetical protein [Mycoplasma hyosynoviae].	33.68	288	168	9	4	286	3	272	5e-37	144
rs:WP_036441435	hypothetical protein [Mycoplasma hyosynoviae].	33.68	288	168	9	4	286	3	272	5e-37	144
rs:WP_026073634	methenyltetrahydrofolate cyclohydrolase [Acetivibrio cellulolyticus].	34.51	284	171	6	8	289	5	275	5e-37	144
rs:WP_036443575	hypothetical protein, partial [Mycoplasma hyosynoviae].	33.68	288	168	9	4	286	3	272	5e-37	144
rs:WP_009139687	tetrahydrofolate dehydrogenase [Slackia piriformis].	33.45	293	180	6	4	292	3	284	6e-37	144
rs:WP_041364009	hypothetical protein [Mycoplasma pulmonis].	31.50	273	168	6	13	284	8	262	6e-37	144
sp:FOLD_MYCPU	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	31.50	273	168	6	13	284	9	263	6e-37	144
rs:WP_003148526	tetrahydrofolate dehydrogenase [Atopobium rimae].	33.72	261	163	4	34	293	32	283	6e-37	144
tr:F7EHA8_MACMU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000016412}; Flags: Fragment;	33.83	269	154	5	18	286	13	257	6e-37	143
tr:K2F337_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	34.74	285	167	6	4	288	15	280	7e-37	144
tr:W5Q3Q5_SHEEP	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOARP00000017344};	49.69	163	47	3	131	291	1	130	7e-37	140
tr:F7EHA0_MACMU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000016414}; Flags: Fragment;	31.93	285	158	5	6	290	5	253	7e-37	143
rs:WP_010245798	tetrahydrofolate dehydrogenase [Peptoniphilus rhinitidis].	32.08	265	169	4	23	286	18	272	7e-37	143
rs:WP_031219179	methenyltetrahydrofolate cyclohydrolase [Alicyclobacillus acidoterrestris].	31.34	284	181	6	6	288	5	275	7e-37	144
tr:H0W7C1_CAVPO	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCPOP00000018875}; Flags: Fragment;	35.89	287	159	11	5	291	17	278	8e-37	143
tr:S9UI97_9TRYP	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPY30542.1};	48.30	147	70	3	149	293	1	143	8e-37	139
rs:WP_033178844	hypothetical protein [Mycoplasma anseris].	33.22	286	171	7	6	288	5	273	9e-37	144
tr:A0A0B1S2B5_OESDE	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:KHJ79498.1};	51.30	154	64	4	141	289	12	159	9e-37	140
tr:A0A010ZNX4_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	34.36	291	177	6	5	293	4	282	9e-37	144
tr:D4K4T4_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	34.87	261	159	4	34	293	32	282	9e-37	143
rs:WP_034445397	methenyltetrahydrofolate cyclohydrolase, partial [Cloacibacillus evryensis].	34.36	291	177	6	5	293	4	282	9e-37	143
rs:WP_046097070	methenyltetrahydrofolate cyclohydrolase [Mycoplasma meleagridis].	31.06	293	188	5	4	290	2	286	1e-36	143
tr:K2EMY3_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	32.06	287	173	6	4	290	2	266	1e-36	143
rs:WP_006300873	methenyltetrahydrofolate cyclohydrolase [Aminomonas paucivorans].	37.19	285	151	9	5	279	3	269	1e-36	143
rs:WP_022362926	bifunctional protein FolD [Eggerthella sp. CAG:298].	32.42	293	186	5	1	292	1	282	1e-36	143
rs:XP_006880469	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like [Elephantulus edwardii].	48.37	153	75	1	141	293	7	155	1e-36	149
tr:W8GMD1_9MOLU	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	33.22	286	175	6	1	285	1	271	1e-36	143
tr:D6PKP8_9ZZZZ	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:ADD96299.1};	56.52	115	50	0	178	292	2	116	1e-36	138
rs:WP_032820179	methenyltetrahydrofolate cyclohydrolase [Oenococcus oeni].	32.64	288	175	5	3	286	2	274	1e-36	143
tr:A0A096B958_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	34.81	270	164	4	3	271	2	260	1e-36	143
rs:WP_047160192	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Trichodesmium erythraeum].	52.50	120	57	0	171	290	1	120	1e-36	138
rs:WP_029891849	methenyltetrahydrofolate cyclohydrolase [Mycoplasma columbinum].	34.71	291	167	9	13	293	8	285	2e-36	142
rs:WP_022184239	bifunctional protein FolD [Eggerthella sp. CAG:209].	37.16	261	153	3	34	293	32	282	2e-36	142
rs:WP_013251658	tetrahydrofolate dehydrogenase [Olsenella uli].	35.15	293	178	6	1	292	1	282	2e-36	142
rs:XP_005401363	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Chinchilla lanigera].	39.32	206	121	1	3	204	46	251	3e-36	142
rs:WP_022369190	bifunctional protein FolD [Firmicutes bacterium CAG:882].	34.36	259	158	3	34	291	31	278	3e-36	142
rs:WP_027122707	methylenetetrahydrofolate dehydrogenase [Mycoplasma spumans].	32.63	285	173	6	4	286	3	270	3e-36	142
rs:WP_007638104	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Rhizobium sp. CCGE 510].	50.00	156	72	3	140	293	5	156	4e-36	138
rs:XP_006274175	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2-like, partial [Alligator mississippiensis].	43.50	177	100	0	3	179	115	291	4e-36	142
tr:X1IMT1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S11995 {ECO:0000313|EMBL:GAH70540.1}; Flags: Fragment;	54.70	117	53	0	174	290	2	118	4e-36	137
tr:E6PFN7_9ZZZZ	SubName: Full=Bifunctional protein folD {ECO:0000313|EMBL:CBH75274.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CBH75274.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CBH75274.1};	33.45	296	179	7	1	292	1	282	5e-36	141
rs:WP_002816628	methenyltetrahydrofolate cyclohydrolase [Oenococcus oeni].	32.29	288	176	5	3	286	2	274	5e-36	141
rs:WP_031505086	methenyltetrahydrofolate cyclohydrolase [Pseudothermotoga hypogea].	35.74	249	145	5	34	282	25	258	5e-36	141
tr:K1UIA1_9ZZZZ	SubName: Full=FolD bifunctional protein {ECO:0000313|EMBL:EKC77955.1};	52.46	122	58	0	126	247	1	122	5e-36	136
rs:WP_004840005	hypothetical protein [[Ruminococcus] gnavus].	34.72	265	147	9	31	290	27	270	6e-36	141
rs:WP_031083767	methenyltetrahydrofolate cyclohydrolase, partial [Streptomyces sp. NRRL WC-3549].	37.57	181	112	1	1	181	1	180	6e-36	138
rs:WP_039736775	methenyltetrahydrofolate cyclohydrolase [Komagataeibacter intermedius].	33.21	277	176	4	17	293	16	283	7e-36	141
tr:A0A0D6Q706_KOMXY	SubName: Full=Bifunctional [5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase] {ECO:0000313|EMBL:GAN98566.1};	31.06	293	193	4	1	293	1	284	7e-36	141
rs:WP_032825867	methenyltetrahydrofolate cyclohydrolase [Oenococcus oeni].	31.94	288	177	5	3	286	2	274	8e-36	141
tr:B9A062_HUMAN	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000386536};	65.74	108	34	2	186	291	96	202	8e-36	139
tr:B9A062_HUMAN	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000386536};	44.62	65	36	0	3	67	37	101	2e-08	62.8
rs:WP_026118742	5,10-methylene-tetrahydrofolate cyclohydrolase [Nocardiopsis salina].	33.80	284	177	3	6	289	12	284	8e-36	141
gpu:CP011232_267	methenyltetrahydrofolate cyclohydrolase [Kosmotoga pacifica]	32.06	287	177	6	5	291	2	270	9e-36	140
rs:WP_010514496	5,10-methylene-tetrahydrofolate dehydrogenase [Komagataeibacter oboediens].	31.06	293	193	4	1	293	1	284	1e-35	140
rs:WP_036574005	methenyltetrahydrofolate cyclohydrolase [Olsenella uli].	34.81	293	179	6	1	292	1	282	1e-35	140
rs:WP_044260265	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Richelia intracellularis].	57.14	126	48	2	161	286	1	120	1e-35	136
rs:WP_002295858	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Streptococcus mutans].	48.25	143	74	0	4	146	3	145	1e-35	136
rs:WP_035433796	methenyltetrahydrofolate cyclohydrolase, partial [Atopobium sp. oral taxon 199].	32.31	260	166	3	34	292	32	282	1e-35	140
rs:WP_043239544	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Streptomyces violaceusniger].	40.56	180	93	2	112	291	4	169	1e-35	137
tr:A0A091UHT0_PHORB	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFQ89717.1}; Flags: Fragment;	64.86	111	36	2	185	293	2	111	1e-35	135
tr:T1ARV4_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EQD59278.1}; Flags: Fragment;	55.97	134	49	2	157	290	2	125	2e-35	135
rs:WP_022936168	methenyltetrahydrofolate cyclohydrolase [Mycoplasma orale].	32.08	293	177	6	1	288	1	276	2e-35	140
tr:X1RWQ1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_L05241 {ECO:0000313|EMBL:GAI85202.1};	43.04	158	90	0	34	191	2	159	2e-35	138
rs:WP_027462117	methenyltetrahydrofolate cyclohydrolase [Deinococcus ficus].	34.71	291	168	10	6	290	16	290	2e-35	140
tr:X1FT91_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_L05603 {ECO:0000313|EMBL:GAH35760.1}; Flags: Fragment;	36.31	179	113	1	1	179	1	178	2e-35	137
rs:WP_032818662	methenyltetrahydrofolate cyclohydrolase [Oenococcus oeni].	32.06	287	176	5	4	286	3	274	2e-35	139
tr:F8XMK9_9GAMM	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EGQ60952.1}; Flags: Fragment;	45.27	148	81	0	1	148	1	148	2e-35	136
rs:WP_027332894	hypothetical protein [Mycoplasma gallinarum].	32.40	287	177	6	4	284	2	277	2e-35	140
rs:XP_006535241	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Mus musculus].	65.77	111	35	2	186	294	170	279	3e-35	139
rs:XP_006535241	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X3 [Mus musculus].	40.87	115	63	1	3	117	70	179	1e-15	84.7
tr:W1NPU3_AMBTC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERM97120.1};	40.00	185	87	2	104	286	2	164	3e-35	136
rs:WP_044730132	methylenetetrahydrofolate dehydrogenase [Mycoplasma hominis].	33.22	292	170	8	3	289	2	273	3e-35	139
rs:WP_002835387	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Campylobacter coli].	59.17	120	39	3	174	293	2	111	3e-35	134
rs:WP_012855469	methylenetetrahydrofolate dehydrogenase [Mycoplasma hominis].	33.22	292	170	8	3	289	2	273	3e-35	139
rs:WP_015088062	tetrahydrofolate dehydrogenase [Candidatus Endolissoclinum faulkneri].	33.80	284	170	8	6	286	4	272	3e-35	139
rs:WP_036439003	methylenetetrahydrofolate dehydrogenase [Mycoplasma hominis].	33.22	292	170	8	3	289	2	273	3e-35	139
gpu:CP011538_198	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase [Mycoplasma hominis]	33.22	292	170	8	3	289	17	288	4e-35	139
rs:WP_019190228	hypothetical protein [Clostridiales bacterium 9403326].	33.22	286	178	4	8	292	2	275	4e-35	139
rs:WP_031699675	methenyltetrahydrofolate cyclohydrolase, partial [Mycobacterium tuberculosis].	38.92	185	112	1	1	185	1	184	4e-35	136
tr:M1ZPZ4_CLOBO	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EKN41317.1}; Flags: Fragment;	42.62	183	90	5	113	292	4	174	5e-35	135
rs:WP_028305688	methenyltetrahydrofolate cyclohydrolase [Deinococcus sp. 2009].	34.36	291	169	10	6	290	1	275	6e-35	139
tr:A0A0C2D1A6_9BILA	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:KIH63128.1};	46.59	176	85	3	119	289	19	190	6e-35	136
rs:XP_005575622	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Macaca fascicularis].	65.74	108	34	2	186	291	213	319	6e-35	140
rs:XP_005575622	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Macaca fascicularis].	46.15	65	35	0	3	67	154	218	1e-08	65.5
rs:WP_032808627	methenyltetrahydrofolate cyclohydrolase [Oenococcus oeni].	31.71	287	177	5	4	286	3	274	6e-35	138
rs:WP_040527671	hypothetical protein [Lamprocystis purpurea].	32.57	261	160	4	34	291	34	281	6e-35	139
tr:D4KCH3_9FIRM	SubName: Full=Draft genome {ECO:0000313|EMBL:CBL02536.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CBL02536.1};	34.01	294	154	9	5	288	2	265	7e-35	138
rs:WP_010503195	methenyltetrahydrofolate cyclohydrolase [Gluconobacter frateurii].	34.52	252	155	3	34	285	30	271	7e-35	138
tr:W1WPB6_9FIRM	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:ETJ19766.1}; Flags: Fragment;	42.42	165	84	2	119	283	1	154	8e-35	135
rs:WP_031396579	methenyltetrahydrofolate cyclohydrolase, partial [Sphingomonas sp. STIS6.2].	47.40	154	70	3	138	291	1	143	8e-35	134
rs:XP_008937697	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like, partial [Merops nubicus].	38.10	210	122	3	34	239	10	215	8e-35	136
rs:WP_002820518	bifunctional protein FolD [Oenococcus oeni].	31.71	287	177	5	4	286	3	274	9e-35	138
rs:WP_038838078	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas aeruginosa].	50.00	132	62	1	110	241	2	129	9e-35	134
rs:WP_020002639	hypothetical protein [Mycoplasma hominis].	33.22	292	170	8	3	289	2	273	9e-35	138
rs:WP_042432108	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. JCD].	35.17	290	176	5	3	291	2	280	9e-35	138
rs:WP_044420546	methylenetetrahydrofolate dehydrogenase [Mycoplasma hominis].	33.22	292	170	8	3	289	2	273	9e-35	138
rs:WP_032810539	methenyltetrahydrofolate cyclohydrolase [Oenococcus oeni].	31.71	287	177	5	4	286	3	274	1e-34	138
rs:XP_009302318	PREDICTED: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like isoform X2 [Danio rerio].	37.85	177	110	0	3	179	51	227	1e-34	137
tr:A0A097NT01_MYCHO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	33.22	292	170	8	3	289	17	288	1e-34	138
rs:WP_002823742	methenyltetrahydrofolate cyclohydrolase [Oenococcus oeni].	31.36	287	178	5	4	286	3	274	1e-34	138
rs:WP_044329481	methylenetetrahydrofolate dehydrogenase [Mycoplasma hominis].	32.88	292	171	8	3	289	2	273	1e-34	138
rs:WP_005698645	tetrahydrofolate dehydrogenase, partial [Haemophilus parainfluenzae].	52.27	132	52	2	161	292	1	121	1e-34	133
rs:WP_009061200	tetrahydrofolate dehydrogenase [Clostridium sp. MSTE9].	35.17	290	176	5	3	291	2	280	1e-34	137
rs:WP_039684830	methenyltetrahydrofolate cyclohydrolase [Deinococcus swuensis].	34.38	288	165	9	8	290	13	281	1e-34	137
tr:L0A7Y9_DEIPD	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	32.30	291	172	8	2	284	14	287	1e-34	138
tr:W4U6Q3_PROAA	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:GAE76492.1};	37.00	200	123	2	1	200	1	197	2e-34	135
rs:WP_022178099	bifunctional protein FolD [Oscillibacter sp. CAG:241].	33.22	289	178	5	5	293	4	277	2e-34	137
sp:FOLD_OENOB	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	31.36	287	178	5	4	286	3	274	2e-34	137
tr:X1SE16_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_L04183 {ECO:0000313|EMBL:GAI73660.1}; Flags: Fragment;	44.37	142	79	0	1	142	1	142	2e-34	133
tr:T0BEY2_9BACL	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	30.82	279	179	6	11	288	1	266	2e-34	137
rs:WP_044897007	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Phascolarctobacterium sp. CAG:266].	47.88	165	74	3	118	282	5	157	2e-34	134
rs:WP_006362186	tetrahydrofolate dehydrogenase [Slackia exigua].	30.00	290	191	5	4	292	3	281	2e-34	137
tr:T0YYC6_9ZZZZ	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:EQD36947.1};	33.06	245	162	1	44	288	2	244	3e-34	136
tr:W4ULQ2_PROAA	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:GAE81762.1};	37.00	200	123	2	1	200	1	197	3e-34	135
tr:S2ZMA1_9ACTN	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	32.28	254	162	3	34	286	32	276	3e-34	137
rs:WP_014465869	methenyltetrahydrofolate cyclohydrolase [Alicyclobacillus acidocaldarius].	32.28	285	173	8	8	288	7	275	3e-34	137
rs:XP_002872937	hypothetical protein ARALYDRAFT_912179 [Arabidopsis lyrata subsp. lyrata].	33.22	301	169	7	5	291	2	284	3e-34	137
rs:WP_041231738	methenyltetrahydrofolate cyclohydrolase [Deinococcus peraridilitoris].	32.64	288	169	8	5	284	1	271	3e-34	136
tr:Q4R8S0_MACFA	SubName: Full=Testis cDNA clone: QtsA-11642, similar to human methylene tetrahydrofolate dehydrogenase (NAD+dependent), methenyltetrahydrofolate cyclohydrolase(MTHFD2), nuclear gene encoding mitochondrial protein,mRN... {ECO:0000313|EMBL:BAE00501.1};	63.89	108	36	2	186	291	96	202	3e-34	135
tr:Q4R8S0_MACFA	SubName: Full=Testis cDNA clone: QtsA-11642, similar to human methylene tetrahydrofolate dehydrogenase (NAD+dependent), methenyltetrahydrofolate cyclohydrolase(MTHFD2), nuclear gene encoding mitochondrial protein,mRN... {ECO:0000313|EMBL:BAE00501.1};	46.15	65	35	0	3	67	37	101	1e-10	69.7
rs:WP_014452242	methenyltetrahydrofolate cyclohydrolase [Fervidobacterium pennivorans].	33.09	278	171	6	13	290	6	268	3e-34	136
tr:F3S9N0_9PROT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.18	253	156	3	34	286	32	276	4e-34	136
rs:XP_009831854	hypothetical protein, variant [Aphanomyces astaci].	31.16	215	140	3	2	212	5	215	4e-34	135
rs:WP_039999037	methenyltetrahydrofolate cyclohydrolase [Gluconacetobacter sp. SXCC-1].	35.18	253	156	3	34	286	33	277	4e-34	136
tr:G3WV58_SARHA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSHAP00000019313};	40.30	201	113	3	11	204	1	201	4e-34	134
tr:S4NWL3_9NEOP	SubName: Full=Bifunctional protein folD {ECO:0000313|EMBL:JAA77990.1}; Flags: Fragment;	39.88	168	101	0	1	168	1	168	5e-34	133
rs:WP_034931352	methenyltetrahydrofolate cyclohydrolase [Komagataeibacter rhaeticus].	35.18	253	156	3	34	286	33	277	5e-34	136
rs:XP_009311542	putative methylenetetrahydrofolate dehydrogenase-like protein [Trypanosoma grayi].	32.87	356	167	9	1	291	1	349	5e-34	139
tr:Z2EQ05_VIBPH	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EVU16531.1};	52.34	128	51	3	164	291	1	118	6e-34	131
rs:WP_031981275	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Acinetobacter baumannii].	38.04	184	112	2	3	185	2	184	6e-34	133
rs:XP_012324335	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC105728511 [Aotus nancymaae].	38.93	244	137	6	3	239	361	599	6e-34	140
rs:WP_026868426	hypothetical protein [Inquilinus limosus].	35.92	284	161	7	8	288	9	274	6e-34	135
tr:A0A068UK61_COFCA	SubName: Full=Coffea canephora DH200=94 genomic scaffold, scaffold_35 {ECO:0000313|EMBL:CDP08851.1};	47.55	143	73	1	34	174	9	151	7e-34	134
rs:XP_012511490	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Propithecus coquereli].	49.30	142	66	2	154	293	83	220	8e-34	141
rs:WP_036585088	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Paenibacillus darwinianus].	55.04	129	48	2	163	291	1	119	9e-34	130
tr:A0A059ADW8_EUCGR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KCW52297.1};	36.67	180	112	1	2	179	67	246	9e-34	135
rs:WP_045433152	methylenetetrahydrofolate dehydrogenase [Mycoplasma canadense].	30.58	291	173	8	4	286	3	272	9e-34	135
tr:A0A075I3C9_9EURY	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP(+)) (FolD) {ECO:0000313|EMBL:AIF21327.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AIF21327.1};	46.20	158	76	3	134	291	4	152	9e-34	132
rs:WP_025300335	hypothetical protein [Candidatus Endolissoclinum faulkneri].	32.16	283	176	6	6	286	3	271	1e-33	135
sp:FOLD_COPPD	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	33.61	244	148	4	50	292	41	271	1e-33	135
tr:A0A059AF56_EUCGR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KCW52296.1};	36.67	180	112	1	2	179	67	246	1e-33	135
rs:WP_022740462	methenyltetrahydrofolate cyclohydrolase [Adlercreutzia equolifaciens].	32.20	295	185	5	3	293	2	285	1e-33	135
rs:XP_005953989	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2-like, partial [Pantholops hodgsonii].	40.68	177	105	0	3	179	34	210	1e-33	133
rs:WP_005955276	tetrahydrofolate dehydrogenase [Peptoniphilus harei].	31.50	254	163	4	34	286	29	272	1e-33	135
rs:XP_012359819	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Nomascus leucogenys].	50.36	139	65	1	155	293	16	150	1e-33	140
rs:WP_035584724	methenyltetrahydrofolate cyclohydrolase [Eggerthella lenta].	32.28	285	181	4	3	286	2	275	1e-33	135
rs:WP_037067780	methenyltetrahydrofolate cyclohydrolase, partial [Rhizobium leguminosarum].	53.38	133	57	2	161	292	14	142	1e-33	131
rs:WP_012812046	methenyltetrahydrofolate cyclohydrolase [Alicyclobacillus acidocaldarius].	30.96	281	182	5	8	288	7	275	2e-33	135
tr:A0A059AFX3_EUCGR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KCW52295.1};	36.67	180	112	1	2	179	67	246	2e-33	135
rs:WP_028264066	methenyltetrahydrofolate cyclohydrolase [Atopobium fossor].	32.88	292	183	6	4	293	3	283	2e-33	135
rs:WP_021997470	bifunctional protein FolD [Ruminococcus sp. CAG:724].	32.63	285	178	6	4	286	2	274	2e-33	134
rs:WP_019134225	hypothetical protein [Kallipyga massiliensis].	31.40	293	188	4	3	294	2	282	2e-33	134
rs:WP_009077447	tetrahydrofolate dehydrogenase [Slackia sp. CM382].	29.31	290	193	5	4	292	3	281	2e-33	134
tr:W6KYV4_9TRYP	SubName: Full=Genomic scaffold, scaffold_1 {ECO:0000313|EMBL:CCW66263.1};	31.90	326	154	5	28	289	32	353	2e-33	137
rs:WP_012869833	methenyltetrahydrofolate cyclohydrolase [Thermanaerovibrio acidaminovorans].	34.01	294	167	10	5	291	3	276	2e-33	134
rs:WP_039736778	methylenetetrahydrofolate dehydrogenase [Komagataeibacter intermedius].	32.64	288	186	3	4	291	3	282	3e-33	134
rs:WP_034513647	methenyltetrahydrofolate cyclohydrolase, partial [Agrobacterium rhizogenes].	40.70	199	111	3	5	200	4	198	3e-33	132
rs:WP_044817324	hypothetical protein, partial [Escherichia coli].	52.42	124	59	0	28	151	2	125	3e-33	129
rs:WP_041082987	methenyltetrahydrofolate cyclohydrolase [Thermotoga profunda].	35.25	278	161	9	5	282	2	260	3e-33	134
rs:WP_009305220	tetrahydrofolate dehydrogenase [Eggerthella sp. 1_3_56FAA].	32.28	285	181	4	3	286	2	275	3e-33	134
rs:WP_013613837	methenyltetrahydrofolate cyclohydrolase [Deinococcus proteolyticus].	32.64	288	178	8	6	290	19	293	3e-33	134
tr:S9XEL6_9CETA	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:EPY86169.1};	48.92	139	67	1	155	293	39	173	3e-33	139
tr:A0A0D6Q5E3_KOMXY	SubName: Full=Bifunctional [5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase] {ECO:0000313|EMBL:GAN98563.1};	32.64	288	186	3	4	291	3	282	4e-33	134
rs:XP_010032810	PREDICTED: bifunctional protein FolD 2-like isoform X5 [Eucalyptus grandis].	36.67	180	112	1	2	179	135	314	4e-33	135
rs:WP_024543996	hypothetical protein [Mycoplasma salivarium].	31.03	290	178	9	4	288	3	275	4e-33	134
sp:FOLD_PYRIL	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	34.78	299	159	10	17	289	8	296	4e-33	134
rs:XP_010032809	PREDICTED: bifunctional protein FolD 2-like isoform X4 [Eucalyptus grandis].	36.67	180	112	1	2	179	135	314	4e-33	135
sp:FOLD_PETMO	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	33.33	273	164	5	17	289	10	264	5e-33	133
rs:WP_007295324	tetrahydrofolate dehydrogenase, partial [delta proteobacterium MLMS-1].	56.48	108	46	1	185	292	3	109	5e-33	128
tr:K2CWW8_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	29.69	293	170	8	6	286	3	271	5e-33	133
tr:T1AKU9_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EQD57103.1};	31.12	286	194	1	6	291	13	295	5e-33	134
tr:X1AIG7_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_L08146 {ECO:0000313|EMBL:GAG82440.1}; Flags: Fragment;	35.64	202	122	3	21	219	2	198	6e-33	131
rs:XP_004987913	FolD protein [Salpingoeca rosetta].	32.79	305	176	6	3	291	24	315	6e-33	134
rs:WP_008338315	methenyltetrahydrofolate cyclohydrolase [Alicyclobacillus acidocaldarius].	30.96	281	182	5	8	288	7	275	6e-33	133
tr:T1I171_RHOPR	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:RPRC010041-PA};	35.68	227	134	4	1	215	50	276	6e-33	133
rs:WP_026140619	hypothetical protein, partial [Candidatus Caldatribacteirum californiense].	64.65	99	28	1	193	291	1	92	7e-33	127
rs:WP_019131935	hypothetical protein [Peptoniphilus obesi].	29.09	275	180	5	4	277	3	263	7e-33	133
rs:WP_009609033	MULTISPECIES: tetrahydrofolate dehydrogenase [Eggerthella].	31.93	285	182	4	3	286	2	275	8e-33	133
rs:WP_037067252	methenyltetrahydrofolate cyclohydrolase, partial [Rhizobium leguminosarum].	52.63	133	58	2	161	292	11	139	9e-33	129
tr:W4PTU7_9BACE	SubName: Full=Mg(2+) chelatase family protein {ECO:0000313|EMBL:GAE22489.1};	65.56	90	31	0	206	295	6	95	1e-32	127
tr:A0A0A1PH59_9FUNG	SubName: Full=Putative C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:CEJ03489.1};	44.06	143	74	2	99	239	1	139	1e-32	129
rs:WP_044293062	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas amygdali].	47.37	152	79	1	1	152	1	151	1e-32	129
rs:WP_010514493	methylenetetrahydrofolate dehydrogenase [Komagataeibacter oboediens].	32.64	288	186	3	4	291	3	282	2e-32	132
rs:WP_029330257	hypothetical protein [Mycoplasma cloacale].	31.12	286	172	8	4	286	3	266	2e-32	132
rs:WP_019773910	hypothetical protein, partial [Streptococcus sobrinus].	49.62	131	66	0	1	131	1	131	2e-32	127
rs:WP_034387279	methenyltetrahydrofolate cyclohydrolase [Deinococcus sp. YIM 77859].	32.54	295	183	8	1	290	1	284	2e-32	132
rs:WP_039453861	methenyltetrahydrofolate cyclohydrolase, partial [Xanthomonas vasicola].	45.34	161	82	2	59	217	2	158	2e-32	128
rs:WP_019771790	hypothetical protein, partial [Streptococcus sobrinus].	49.62	131	66	0	1	131	1	131	2e-32	127
rs:WP_029475411	methenyltetrahydrofolate cyclohydrolase [Deinococcus frigens].	32.54	295	165	10	1	290	1	266	2e-32	131
rs:WP_046842681	methenyltetrahydrofolate cyclohydrolase ['Deinococcus soli' Cha et al. 2014].	31.03	290	177	9	6	290	11	282	3e-32	131
rs:WP_041289051	methenyltetrahydrofolate cyclohydrolase [Kosmotoga olearia].	29.07	289	187	6	5	293	2	272	3e-32	131
tr:X1AQZ4_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_L05695 {ECO:0000313|EMBL:GAG85204.1}; Flags: Fragment;	39.02	164	100	0	3	166	2	165	3e-32	128
rs:WP_009644080	tetrahydrofolate dehydrogenase [Mogibacterium sp. CM50].	31.36	287	175	8	15	290	10	285	3e-32	131
tr:H1A3Y4_TAEGU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTGUP00000017599}; Flags: Fragment;	50.00	126	63	0	26	151	3	128	3e-32	127
rs:WP_031512585	methenyltetrahydrofolate cyclohydrolase, partial [Corynebacterium crenatum].	39.66	179	107	1	1	179	1	178	3e-32	128
tr:A0A099VC05_9HELI	SubName: Full=5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:KGL29723.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KGL29723.1}; EC=3.5.4.9 {ECO:0000313|EMBL:KGL29723.1}; Flags: Fragment;	46.15	143	76	1	5	147	3	144	3e-32	127
sp:FOLD_KOSOT	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	29.07	289	187	6	5	293	4	274	3e-32	131
rs:WP_037213626	methenyltetrahydrofolate cyclohydrolase, partial [Rhodococcus sp. R04].	38.92	185	110	2	1	185	1	182	3e-32	129
rs:XP_004335354	tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)binding domain containing protein [Acanthamoeba castellanii str. Neff].	51.41	142	63	3	155	291	307	447	3e-32	134
rs:WP_032705921	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Salinispora arenicola].	44.16	154	72	2	138	291	17	156	3e-32	127
rs:WP_019138974	tetrahydrofolate dehydrogenase [Peptoniphilus timonensis].	32.22	270	168	5	18	286	17	272	3e-32	131
tr:L9LC04_TUPCH	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:ELW72438.1};	57.48	127	46	4	174	294	2	126	3e-32	127
tr:R6HF60_9FIRM	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:CDB35530.1};	48.08	156	69	3	127	282	3	146	3e-32	127
rs:WP_034907508	hypothetical protein, partial [Eremococcus coleocola].	40.12	172	93	2	117	288	4	165	4e-32	128
rs:WP_040551161	methenyltetrahydrofolate cyclohydrolase, partial [Pyramidobacter piscolens].	37.67	215	128	3	3	216	2	211	4e-32	129
rs:WP_034266284	hypothetical protein, partial [Aminiphilus circumscriptus].	31.45	283	180	7	6	286	5	275	5e-32	130
tr:D1Y7Z5_9BACT	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein {ECO:0000313|EMBL:EFB89598.1}; Flags: Fragment;	37.67	215	128	3	3	216	5	214	5e-32	129
rs:WP_004414741	methylenetetrahydrofolate dehydrogenase [Mycoplasma arginini].	26.99	289	189	7	4	288	3	273	5e-32	130
rs:WP_019789770	hypothetical protein, partial [Streptococcus sobrinus].	49.61	129	65	0	1	129	1	129	5e-32	126
tr:A0A0D6MP79_9PROT	SubName: Full=Protein folD {ECO:0000313|EMBL:GAN55497.1};	34.11	214	132	2	76	289	71	275	6e-32	131
tr:H0YTH3_TAEGU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTGUP00000001586}; Flags: Fragment;	45.33	150	82	0	3	152	49	198	6e-32	128
tr:E9GV25_DAPPU	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EFX76591.1};	57.27	110	42	2	188	292	18	127	6e-32	127
tr:A0A0C6FXV5_MYCAR	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	26.99	289	189	7	4	288	3	273	8e-32	130
tr:X0UUY1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S11128 {ECO:0000313|EMBL:GAG09520.1}; Flags: Fragment;	37.36	182	103	2	110	291	1	171	9e-32	127
tr:K2CDS2_9BACT	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKD79113.1};	44.14	145	70	2	147	291	1	134	9e-32	126
tr:W4PDM9_9BACE	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:GAE17877.1};	65.17	89	31	0	206	294	6	94	9e-32	124
rs:XP_009609710	PREDICTED: bifunctional protein FolD 2-like, partial [Nicotiana tomentosiformis].	44.06	143	78	1	32	172	3	145	9e-32	126
rs:WP_016309354	hypothetical protein [Enterorhabdus caecimuris].	32.19	292	183	5	3	290	2	282	9e-32	130
rs:WP_036379689	hypothetical protein [Mogibacterium timidum].	31.01	287	176	8	15	290	10	285	1e-31	130
rs:WP_034436932	hypothetical protein [Clostridiales bacterium S5-A11].	35.66	286	171	4	6	291	4	276	1e-31	130
rs:WP_044535144	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Bacteroides intestinalis].	48.39	124	64	0	5	128	3	126	1e-31	125
rs:WP_021793353	bifunctional protein FolD [Thermoplasmatales archaeon E-plasma].	28.77	292	195	5	3	293	2	281	1e-31	130
tr:S9U9Y7_9TRYP	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPY25758.1};	44.22	147	76	2	149	293	1	143	1e-31	125
tr:X1PI94_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S11723 {ECO:0000313|EMBL:GAI38775.1}; Flags: Fragment;	40.23	174	103	1	1	174	1	173	1e-31	126
rs:WP_022135848	bifunctional protein FolD [Firmicutes bacterium CAG:176].	35.74	291	172	5	3	290	2	280	1e-31	129
rs:WP_032705413	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Salinispora arenicola].	43.51	154	73	2	138	291	17	156	1e-31	126
tr:C6SH66_NEIME	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:CBA04696.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CBA04696.1}; Flags: Fragment;	49.62	133	67	0	1	133	1	133	2e-31	125
rs:WP_043416385	methenyltetrahydrofolate cyclohydrolase, partial [Streptomyces pluripotens].	42.42	165	94	1	1	165	1	164	2e-31	126
rs:WP_013557055	methenyltetrahydrofolate cyclohydrolase [Deinococcus maricopensis].	31.10	299	186	9	2	297	7	288	2e-31	129
rs:WP_027119786	hypothetical protein [Mycoplasma testudinis].	28.77	285	186	4	6	290	4	271	2e-31	129
tr:K2E4V6_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKE05163.1}; Flags: Fragment;	34.15	205	131	1	33	237	32	232	2e-31	128
tr:A0A075I1Z1_9ARCH	SubName: Full=Methylenetetrahydrofolate dehydrogenase (FolD) {ECO:0000313|EMBL:AIF21924.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AIF21924.1};	48.25	143	61	4	149	289	1	132	2e-31	125
rs:WP_019010348	hypothetical protein [Deinococcus aquatilis].	31.35	303	175	11	1	290	1	283	2e-31	129
rs:WP_032727498	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Salinispora arenicola].	42.86	154	74	2	138	291	17	156	3e-31	125
rs:XP_002188366	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Taeniopygia guttata].	49.23	130	66	0	26	155	45	174	3e-31	128
rs:XP_002188366	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Taeniopygia guttata].	71.43	42	12	0	250	291	206	247	3e-08	63.5
rs:WP_032713043	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Salinispora arenicola].	43.51	154	73	2	138	291	17	156	3e-31	125
tr:K1U3X2_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKC74584.1};	54.14	133	51	2	157	289	9	131	3e-31	124
rs:WP_032724815	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Salinispora arenicola].	42.21	154	75	2	138	291	17	156	3e-31	125
tr:S4PWI0_9NEOP	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:JAA85807.1};	61.32	106	37	2	188	291	17	120	4e-31	124
rs:WP_019584982	methenyltetrahydrofolate cyclohydrolase [Deinococcus apachensis].	33.56	289	170	10	8	290	9	281	4e-31	128
tr:G1SP76_RABIT	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOCUP00000004829};	66.32	95	31	1	197	291	109	202	5e-31	126
tr:G1SP76_RABIT	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOCUP00000004829};	41.46	82	48	0	3	84	37	118	7e-10	67.0
tr:F8XPF1_9GAMM	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EGQ61594.1}; Flags: Fragment;	52.43	103	43	1	188	290	4	100	5e-31	124
tr:R7VX27_COLLI	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:EMC87231.1}; Flags: Fragment;	49.21	126	64	0	26	151	2	127	5e-31	124
tr:K2E4H4_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	30.38	293	170	8	5	291	4	268	6e-31	127
rs:WP_018288067	hypothetical protein, partial [zeta proteobacterium SCGC AB-133-G06].	56.73	104	44	1	188	291	8	110	7e-31	123
sp:FOLD_MYCGA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	30.31	287	176	8	6	286	5	273	7e-31	127
tr:K5B934_9MYCO	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:EKF24753.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EKF24753.1}; Flags: Fragment;	40.12	167	93	2	1	164	1	163	7e-31	124
tr:I4DPD1_PAPXU	SubName: Full=NAD-dependent methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:BAM19771.1};	53.91	128	44	4	174	291	2	124	8e-31	123
tr:X0VZJ0_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S23116 {ECO:0000313|EMBL:GAG16487.1}; Flags: Fragment;	54.47	123	48	2	168	290	2	116	1e-30	123
tr:A0A0B0HV89_9BACL	SubName: Full=Bifunctional protein FolD protein {ECO:0000313|EMBL:KHF32502.1};	47.92	144	74	1	1	144	1	143	1e-30	123
rs:WP_031440981	methenyltetrahydrofolate cyclohydrolase, partial [Sphingomonas sp. FUKUSWIS1].	46.26	147	68	3	145	291	2	137	1e-30	123
tr:J9GPP4_9ZZZZ	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EJX01955.1};	55.77	104	46	0	191	294	2	105	2e-30	122
rs:WP_032717193	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Salinispora arenicola].	42.21	154	75	2	138	291	17	156	2e-30	123
rs:XP_011330629	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like isoform X4 [Cerapachys biroi].	32.98	285	143	4	3	239	36	320	2e-30	127
rs:XP_004328030	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2-like, partial [Tursiops truncatus].	35.05	214	105	2	3	214	51	232	2e-30	125
rs:XP_006790159	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2-like [Neolamprologus brichardi].	43.83	162	84	3	103	258	9	169	2e-30	123
rs:WP_021789550	hypothetical protein [Thermoplasmatales archaeon Gpl].	29.31	290	191	4	1	289	1	277	2e-30	126
rs:WP_028026946	methenyltetrahydrofolate cyclohydrolase [Enterorhabdus mucosicola].	30.48	292	188	5	3	290	2	282	3e-30	126
rs:WP_028794142	hypothetical protein [Thalassobaculum salexigens].	31.51	292	184	6	6	295	3	280	3e-30	125
tr:M1X4B7_9NOST	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:CCH65881.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CCH65881.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CCH65881.1};	60.00	100	38	1	187	286	6	103	3e-30	121
rs:WP_045078799	tetrahydrofolate dehydrogenase [Peptoniphilus sp. 1-1].	29.80	255	168	3	33	286	28	272	3e-30	125
rs:WP_014886307	methenyltetrahydrofolate cyclohydrolase [Mycoplasma gallisepticum].	29.97	287	177	8	6	286	5	273	3e-30	125
tr:K1XTW5_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	29.47	285	181	5	6	284	4	274	4e-30	125
tr:F6QQ06_CALJA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCJAP00000045628}; Flags: Fragment;	36.82	239	123	6	8	241	18	233	4e-30	124
rs:WP_004424858	methylenetetrahydrofolate dehydrogenase [Mycoplasma auris].	31.58	285	176	8	5	286	4	272	5e-30	125
rs:WP_027459330	methenyltetrahydrofolate cyclohydrolase [Deinococcus murrayi].	32.31	294	180	9	2	290	4	283	5e-30	125
rs:WP_009712227	methylenetetrahydrofolate dehydrogenase, partial [Streptomyces himastatinicus].	36.93	176	110	1	1	176	1	175	7e-30	122
gp:AE016827_1851	FolD protein [Mannheimia succiniciproducens MBEL55E]	50.00	130	55	2	163	292	1	120	7e-30	120
rs:WP_039897870	methenyltetrahydrofolate cyclohydrolase, partial [Mycobacterium hassiacum].	40.12	162	90	2	6	164	3	160	8e-30	121
rs:WP_017869058	MULTISPECIES: methenyltetrahydrofolate cyclohydrolase [Deinococcus].	31.08	296	184	10	8	297	14	295	9e-30	125
rs:WP_014574826	methenyltetrahydrofolate cyclohydrolase [Mycoplasma gallisepticum].	30.18	285	179	7	6	286	5	273	1e-29	124
rs:WP_029479747	methenyltetrahydrofolate cyclohydrolase [Deinococcus marmoris].	33.33	288	168	9	8	290	15	283	1e-29	124
tr:A0A067M309_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDQ05956.1}; Flags: Fragment;	35.53	197	121	2	1	197	1	191	1e-29	122
gp:CP006916_819	methenyltetrahydrofolate cyclohydrolase [Mycoplasma gallisepticum S6]	29.08	282	186	5	6	286	5	273	1e-29	124
rs:XP_001691791	methylenetetrahydrofolate dehydrogenase/ methylenetetrahydrofolate cyclohydrolase [Chlamydomonas reinhardtii].	34.01	247	106	4	1	243	25	218	2e-29	125
tr:K2AK73_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	35.02	297	148	11	5	289	4	267	2e-29	124
rs:WP_022266705	bifunctional protein FolD [Firmicutes bacterium CAG:449].	30.74	283	175	5	4	286	2	263	2e-29	124
rs:WP_043901489	hypothetical protein [candidate division SR1 bacterium RAAC1_SR1_1].	32.60	273	158	9	35	291	17	279	2e-29	124
rs:XP_004337875	tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)binding domain containing protein [Acanthamoeba castellanii str. Neff].	54.39	114	48	1	178	291	1	110	2e-29	119
gp:CP006913_802	methylenetetrahydrofolate dehydrogenase [candidate division SR1 bacterium RAAC1_SR1_1]	32.60	273	158	9	35	291	28	290	2e-29	124
tr:A7BLY5_9GAMM	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:EDN72450.1};	48.84	129	56	2	162	290	9	127	2e-29	119
sp:FOLD_PYRAR	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	32.67	300	172	9	6	286	5	293	2e-29	124
tr:X1JX42_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S25815 {ECO:0000313|EMBL:GAH82834.1}; Flags: Fragment;	51.33	113	51	1	117	229	2	110	2e-29	119
sp:FOLD1_SYNWW	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	32.19	292	176	6	4	291	2	275	2e-29	123
tr:E7NX58_TREPH	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein {ECO:0000313|EMBL:EFW36843.1};	41.72	151	87	1	1	151	1	150	2e-29	120
tr:A0A090P917_9VIBR	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:GAK86525.1}; EC=1.5.1.5 {ECO:0000313|EMBL:GAK86525.1}; EC=3.5.4.9 {ECO:0000313|EMBL:GAK86525.1};	54.81	104	41	2	188	291	10	107	2e-29	119
rs:XP_012339939	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Apis florea].	58.49	106	39	2	189	292	2	104	3e-29	119
sp:FOLD_PYRAE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	35.66	272	146	9	34	286	32	293	3e-29	124
tr:H2PEN0_PONAB	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000016946}; Flags: Fragment;	39.15	212	108	8	89	295	21	216	3e-29	122
rs:WP_034439525	hypothetical protein, partial [Clostridiales bacterium S5-A11].	33.60	247	148	7	41	286	2	233	3e-29	122
rs:WP_034405866	methenyltetrahydrofolate cyclohydrolase [Deinococcus sp. RL].	32.20	295	179	10	2	290	4	283	5e-29	123
tr:A0A090QW84_9GAMM	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:GAL07440.1}; EC=1.5.1.5 {ECO:0000313|EMBL:GAL07440.1}; EC=3.5.4.9 {ECO:0000313|EMBL:GAL07440.1};	53.28	122	57	0	1	122	1	122	5e-29	119
rs:WP_007398666	protein folD [Gluconacetobacter sp. SXCC-1].	36.32	234	135	4	58	291	64	283	5e-29	123
tr:K2DD03_9BACT	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKD95326.1}; Flags: Fragment;	33.59	256	146	6	41	291	1	237	6e-29	121
rs:XP_004600150	PREDICTED: LOW QUALITY PROTEIN: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Ochotona princeps].	35.78	218	131	4	3	214	10	224	6e-29	121
rs:WP_009848491	methylenetetrahydrofolate dehydrogenase, partial [Vibrio sp. MED222].	54.81	104	41	2	188	291	9	106	6e-29	117
tr:T0YS83_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP(+)) {ECO:0000313|EMBL:EQD34677.1}; Flags: Fragment;	51.64	122	49	2	136	257	2	113	6e-29	117
rs:WP_034931346	methylenetetrahydrofolate dehydrogenase [Komagataeibacter rhaeticus].	35.59	236	138	4	58	293	64	285	8e-29	122
rs:WP_010165621	FolD bifunctional protein [candidate division TM7 single-cell isolate TM7c].	32.53	292	168	8	4	292	2	267	8e-29	122
rs:WP_014894095	methenyltetrahydrofolate cyclohydrolase [Mycoplasma genitalium].	29.17	288	178	6	6	292	3	265	8e-29	122
tr:F3MLX5_LACHE	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EGF36832.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EGF36832.1}; Flags: Fragment;	56.14	114	39	2	170	283	1	103	8e-29	117
tr:A0A067NFB7_PLEOS	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDQ26544.1};	35.48	217	124	4	3	216	12	215	9e-29	120
sp:FOLD_MYCGE	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	29.17	288	178	6	6	292	3	265	1e-28	121
rs:WP_022148533	bifunctional protein FolD [Bacteroides sp. CAG:709].	53.23	124	49	3	163	286	1	115	1e-28	117
rs:WP_014893893	methenyltetrahydrofolate cyclohydrolase [Mycoplasma genitalium].	29.17	288	178	6	6	292	3	265	1e-28	121
tr:A0A016QRT5_9DEIO	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	32.07	290	175	10	6	290	4	276	1e-28	121
rs:WP_034355194	methenyltetrahydrofolate cyclohydrolase [Deinococcus phoenicis].	32.07	290	175	10	6	290	9	281	1e-28	121
tr:A0A075HG27_9EURY	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase (FolD) {ECO:0000313|EMBL:AIF14150.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AIF14150.1};	45.83	144	69	3	149	292	1	135	1e-28	117
sp:FOLD_PYRNV	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	36.63	273	144	9	34	287	32	294	1e-28	122
sp:FOLD_PYRCJ	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	33.57	277	151	8	34	289	28	292	2e-28	121
rs:WP_022314912	bifunctional protein FolD, partial [Ruminococcus sp. CAG:382].	54.05	111	40	2	175	285	1	100	2e-28	116
tr:X1G4B5_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_L00116 {ECO:0000313|EMBL:GAH27863.1}; Flags: Fragment;	63.04	92	33	1	199	290	1	91	2e-28	115
tr:K0RCN9_THAOC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJK44252.1};	31.05	306	178	9	2	289	350	640	2e-28	125
tr:V9IK93_APICE	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:AEY61548.1};	36.68	199	118	4	5	199	9	203	2e-28	119
tr:F9MWZ6_9FIRM	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EGS31185.1};	31.00	271	169	8	17	286	14	267	2e-28	120
rs:WP_016671152	methylenetetrahydrofolate dehydrogenase, partial [Yersinia pestis].	51.33	113	49	2	179	291	2	108	2e-28	116
rs:WP_031897483	methenyltetrahydrofolate cyclohydrolase, partial [Staphylococcus aureus].	42.03	138	79	1	1	138	1	137	3e-28	117
rs:WP_027347533	hypothetical protein [Helcococcus sueciensis].	27.34	278	191	2	15	292	8	274	4e-28	120
tr:X1HB35_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_L00807 {ECO:0000313|EMBL:GAH42508.1}; Flags: Fragment;	52.59	116	45	1	188	293	5	120	4e-28	115
tr:J2XBW3_KLEPN	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EJK92300.1};	52.21	113	48	2	179	291	1	107	5e-28	115
rs:WP_018201285	hypothetical protein [Candidatus Microgenomatus auricola].	28.47	288	181	5	6	288	3	270	5e-28	119
tr:A0A097ARE2_THEKI	SubName: Full=5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase FolD {ECO:0000313|EMBL:AIS52380.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AIS52380.1}; EC=3.5.4.9 {ECO:0000313|EMBL:AIS52380.1};	45.74	129	59	2	165	293	8	125	6e-28	115
rs:XP_011814058	PREDICTED: LOW QUALITY PROTEIN: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Colobus angolensis palliatus].	64.08	103	33	3	188	288	192	292	7e-28	120
rs:XP_011814058	PREDICTED: LOW QUALITY PROTEIN: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Colobus angolensis palliatus].	40.98	61	36	0	5	65	130	190	2e-07	61.6
tr:A0A068Y1M3_ECHMU	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:CDS35989.1}; EC=1.5.1.15 {ECO:0000313|EMBL:CDS35989.1};	41.29	155	75	5	140	291	22	163	8e-28	117
tr:I2G7N6_MILFA	SubName: Full=PISO-ORF0013814.mRNA {ECO:0000313|EMBL:CCG00932.1}; Flags: Fragment;	40.91	154	83	3	78	227	4	153	9e-28	115
tr:G5PJH4_SALET	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EHC75904.1};	56.86	102	38	2	188	289	8	103	9e-28	114
rs:WP_044818448	methenyltetrahydrofolate cyclohydrolase, partial [Escherichia coli].	53.64	110	45	2	188	297	7	110	9e-28	114
tr:S9VKA1_9TRYP	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:EPY41279.1};	33.43	350	162	11	2	288	10	351	1e-27	120
rs:WP_039881184	hypothetical protein, partial [Peptoniphilus sp. oral taxon 375].	32.79	247	150	7	41	286	2	233	1e-27	118
tr:F8J4Q4_MILFA	SubName: Full=Mitochondrial C1-tetrahydrofolate synthase {ECO:0000313|EMBL:CBN80551.1}; Flags: Fragment;	40.76	157	85	3	74	226	2	154	1e-27	115
tr:S9X408_9TRYP	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:EPY43145.1};	32.86	350	164	10	2	288	10	351	1e-27	120
rs:WP_014325285	methenyltetrahydrofolate cyclohydrolase [Mycoplasma pneumoniae].	31.07	280	167	7	6	284	3	257	1e-27	118
tr:A0A067HGX7_CITSI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDO87307.1};	41.50	147	84	1	3	147	9	155	1e-27	115
rs:WP_033811446	hypothetical protein, partial [Escherichia coli].	51.24	121	59	0	1	121	1	121	1e-27	114
tr:U6DVX2_NEOVI	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+-dependent) 1 {ECO:0000313|EMBL:CCP86192.1}; Flags: Fragment;	36.00	200	119	4	3	197	47	242	2e-27	117
rs:WP_044820644	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Bacteroides fragilis].	53.00	100	47	0	34	133	5	104	2e-27	114
tr:F8J4Q2_MILFA	SubName: Full=Mitochondrial C1-tetrahydrofolate synthase {ECO:0000313|EMBL:CBN80549.1}; Flags: Fragment;	40.91	154	83	3	78	227	4	153	2e-27	115
tr:A0A0D0G8W4_LACBR	SubName: Full=Lactobacillus brevis strain TMW 1.313 Scaffold_1_TMW1313, whole genome shotgun sequence {ECO:0000313|EMBL:KIO95979.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KIO95979.1}; EC=3.5.4.9 {ECO:0000313|EMBL:KIO95979.1};	50.00	130	55	3	157	286	9	128	2e-27	114
rs:WP_009540413	methylenetetrahydrofolate dehydrogenase [Caenispirillum salinarum].	27.74	292	203	3	3	292	4	289	2e-27	118
tr:A0A060WI82_ONCMY	SubName: Full=Oncorhynchus mykiss genomic scaffold, scaffold_289 {ECO:0000313|EMBL:CDQ66867.1};	38.24	204	115	5	3	200	24	222	2e-27	117
rs:WP_006583599	methenyltetrahydrofolate cyclohydrolase [Thermanaerovibrio velox].	32.62	279	163	9	5	277	3	262	2e-27	118
rs:XP_002872899	hypothetical protein ARALYDRAFT_912107 [Arabidopsis lyrata subsp. lyrata].	38.62	189	99	5	108	292	32	207	2e-27	116
sp:FOLD1_DEIGD	RecName: Full=Bifunctional protein FolD 1 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	31.42	296	181	10	1	290	1	280	2e-27	118
rs:WP_034512945	methenyltetrahydrofolate cyclohydrolase, partial [Agrobacterium rhizogenes].	50.00	122	56	2	172	292	2	119	2e-27	114
tr:U2JIF7_LACPN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERJ62443.2}; Flags: Fragment;	52.34	128	51	3	165	292	1	118	3e-27	113
rs:WP_025498311	hypothetical protein [candidate division TM7 bacterium JGI 0001002-L20].	30.27	294	172	8	4	292	3	268	3e-27	117
rs:WP_016369197	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Lactobacillus paracasei].	39.24	158	95	1	6	163	5	161	3e-27	114
tr:E7NX57_TREPH	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EFW36842.1};	62.50	88	32	1	205	292	1	87	3e-27	112
sp:FOLD_DEIRA	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	32.77	296	179	11	8	297	17	298	3e-27	118
rs:WP_021104729	bifunctional protein FolD, partial [Propionibacterium granulosum].	41.33	150	87	1	1	150	1	149	3e-27	114
tr:X1PQM2_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S15122 {ECO:0000313|EMBL:GAI33194.1}; Flags: Fragment;	46.97	132	56	3	165	293	1	121	4e-27	113
rs:WP_002294993	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Streptococcus mutans].	45.45	143	78	0	4	146	3	145	4e-27	114
rs:WP_014288242	methenyltetrahydrofolate cyclohydrolase [Pyrobaculum sp. 1860].	30.79	302	175	9	6	286	5	293	4e-27	118
tr:F8J4Q3_9ASCO	SubName: Full=Mitochondrial C1-tetrahydrofolate synthase {ECO:0000313|EMBL:CBN80550.1}; Flags: Fragment;	40.91	154	83	3	74	223	2	151	4e-27	114
rs:WP_031890530	methenyltetrahydrofolate cyclohydrolase, partial [Staphylococcus aureus].	42.22	135	77	1	1	135	1	134	4e-27	113
rs:WP_023793308	FolD bifunctional protein, nonfunctional [Candidatus Saccharibacteria bacterium RAAC3_TM7_1].	26.12	291	189	6	4	293	2	267	4e-27	117
tr:A0A068WWC6_ECHGR	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:CDS22773.1};	41.29	155	75	5	140	291	22	163	5e-27	114
sp:FOLD_MYCPN	RecName: Full=Bifunctional protein FolD {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=1.5.1.5 {ECO:0000255|HAMAP-Rule:MF_01576}; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000255|HAMAP-Rule:MF_01576}; EC=3.5.4.9 {ECO:0000255|HAMAP-Rule:MF_01576};	30.71	280	168	7	6	284	3	257	6e-27	116
tr:S8C0E4_9LAMI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPS60119.1}; Flags: Fragment;	39.33	150	89	1	2	149	5	154	6e-27	113
rs:WP_021104730	bifunctional protein FolD, partial [Propionibacterium granulosum].	42.86	140	71	3	152	291	1	131	7e-27	113
tr:F1SLH1_PIG	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSSCP00000027372}; Flags: Fragment;	70.13	77	22	1	215	291	1	76	7e-27	111
tr:G8AE20_9ASCO	SubName: Full=Mitochondrial C1-tetrahydrofolate synthase {ECO:0000313|EMBL:CCC86708.1}; Flags: Fragment;	41.33	150	80	3	78	223	2	147	8e-27	113
tr:W6U684_ECHGR	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:EUB56728.1};	41.29	155	75	5	140	291	48	189	9e-27	114
gpu:CP011268_740	Bifunctional protein FolD protein [candidate division SR1 bacterium Aalborg_AAW-1]	29.90	291	179	10	1	284	5	277	9e-27	116
rs:WP_036637779	methenyltetrahydrofolate cyclohydrolase, partial [Paenirhodobacter enshiensis].	49.59	123	57	2	171	292	1	119	1e-26	112
rs:WP_027122259	methenyltetrahydrofolate cyclohydrolase [Mycoplasma imitans].	27.21	283	190	5	6	286	5	273	1e-26	116
rs:WP_036753784	tetrahydrofolate dehydrogenase [Peptoniphilus lacrimalis].	29.50	261	172	5	15	274	21	270	1e-26	116
tr:A0A095ZL54_9FIRM	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	29.50	261	172	5	15	274	10	259	1e-26	115
tr:F8J4Q1_MILFA	SubName: Full=Mitochondrial C1-tetrahydrofolate synthase {ECO:0000313|EMBL:CBN80548.1}; Flags: Fragment;	40.52	153	83	3	78	226	2	150	1e-26	112
rs:WP_026122618	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Nocardiopsis halotolerans].	33.80	213	136	2	5	217	9	216	1e-26	114
rs:WP_025948228	hypothetical protein, partial [Prochlorococcus sp. scB243_495I8].	44.74	114	63	0	32	145	12	125	1e-26	111
tr:J2H625_9SPHN	SubName: Full=5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EJL30868.1};	48.15	135	63	3	158	292	11	138	2e-26	112
tr:X6JBY6_9RHIZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESZ53659.1};	52.99	117	49	3	175	290	1	112	2e-26	111
tr:A0A076N0I6_AMYME	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:AIJ23322.1};	40.96	166	97	1	1	166	1	165	2e-26	117
tr:G8AE16_MILFA	SubName: Full=Mitochondrial C1-tetrahydrofolate synthase {ECO:0000313|EMBL:CCC86704.1}; Flags: Fragment;	41.33	150	80	3	78	223	2	147	2e-26	112
rs:WP_023501015	5,10-methylene-tetrahydrofolate dehydrogenase, partial [uncultured archaeon A07HB70].	53.78	119	52	1	171	289	1	116	2e-26	111
tr:X1RB08_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S21799 {ECO:0000313|EMBL:GAI52769.1}; Flags: Fragment;	41.78	146	84	1	3	148	2	146	2e-26	112
tr:M0TVX4_MUSAM	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:GSMUA_Achr8P33720_001};	50.00	106	53	0	188	293	15	120	3e-26	110
rs:WP_036286524	hypothetical protein [Methylosinus sp. PW1].	31.01	287	178	5	2	286	6	274	4e-26	114
rs:WP_029945945	methenyltetrahydrofolate cyclohydrolase, partial [Aminicenantes bacterium SCGC AAA252-P19].	63.04	92	30	2	203	290	1	92	4e-26	109
rs:WP_038374888	methenyltetrahydrofolate cyclohydrolase, partial [Borrelia burgdorferi].	32.04	206	135	4	36	239	33	235	4e-26	114
rs:WP_003815562	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Bifidobacterium bifidum].	39.74	151	87	3	143	293	1	147	4e-26	111
rs:WP_036617306	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Parabacteroides distasonis].	61.90	84	32	0	211	294	1	84	4e-26	109
rs:WP_039943052	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Lactobacillus equicursoris].	38.41	164	100	1	3	166	2	164	4e-26	111
rs:WP_018265928	hypothetical protein [Methylosinus sp. LW4].	31.01	287	178	5	2	286	6	274	4e-26	114
tr:W1HTH2_KLEPN	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:CDL62248.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CDL62248.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CDL62248.1};	54.29	105	48	0	1	105	1	105	5e-26	110
rs:WP_004823871	tetrahydrofolate dehydrogenase [Peptoniphilus lacrimalis].	29.50	261	172	5	15	274	21	270	5e-26	114
tr:K1TBJ9_9ZZZZ	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKC56591.1}; Flags: Fragment;	44.97	149	73	3	145	293	9	148	5e-26	111
rs:WP_022723480	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Rhodopseudomonas sp. B29].	44.90	147	76	2	143	289	1	142	6e-26	110
rs:XP_009209984	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Papio anubis].	53.77	106	48	1	188	293	10	114	7e-26	118
rs:XP_005561524	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Macaca fascicularis].	53.77	106	48	1	188	293	10	114	7e-26	118
rs:WP_040223322	methenyltetrahydrofolate cyclohydrolase, partial [Klebsiella pneumoniae].	54.00	100	40	2	192	291	1	94	7e-26	109
rs:WP_001073411	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Leptospira interrogans].	39.74	156	90	1	58	213	1	152	8e-26	110
rs:WP_035173470	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Lactobacillus equicursoris].	38.41	164	100	1	3	166	2	164	9e-26	110
tr:G8AE14_MILFA	SubName: Full=Mitochondrial C1-tetrahydrofolate synthase {ECO:0000313|EMBL:CCC86702.1}; Flags: Fragment;	40.67	150	81	3	78	223	2	147	9e-26	110
tr:W1X0Z1_9ZZZZ	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:ETJ22369.1}; Flags: Fragment;	55.00	100	45	0	75	174	2	101	9e-26	108
rs:WP_022256352	bifunctional protein FolD [Faecalibacterium sp. CAG:82].	40.38	156	83	3	138	293	9	154	1e-25	110
rs:WP_006597764	tetrahydrofolate dehydrogenase [Pseudoramibacter alactolyticus].	31.14	289	184	6	6	291	8	284	1e-25	113
rs:WP_041890101	hypothetical protein [candidate division SR1 bacterium MGEHA].	25.97	308	188	9	5	286	2	295	1e-25	113
rs:WP_016920788	hypothetical protein [Methylocystis parvus].	31.80	261	162	5	29	286	27	274	1e-25	113
rs:WP_008902287	5,10-methylene-tetrahydrofolate dehydrogenase [Peptoniphilus duerdenii].	30.34	267	173	4	21	286	18	272	1e-25	113
rs:WP_005397649	hypothetical protein [Helcococcus kunzii].	31.62	253	160	4	34	285	27	267	2e-25	112
rs:WP_021791783	hypothetical protein [Thermoplasmatales archaeon I-plasma].	28.92	287	181	6	5	290	2	266	2e-25	112
tr:F0G1I6_9BURK	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EGD04643.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EGD04643.1};	51.92	104	44	1	188	291	10	107	2e-25	108
tr:S9W4R3_9TRYP	SubName: Full=Methylenetetrahydrofolate dehydrogenase-like protein {ECO:0000313|EMBL:EPY34331.1};	29.58	355	174	7	3	288	11	358	2e-25	114
tr:G3IBU1_CRIGR	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:EGW10951.1};	76.06	71	16	1	224	294	1	70	2e-25	107
tr:D6PKP7_9ZZZZ	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:ADD96298.1};	35.37	164	102	2	4	166	2	162	3e-25	109
rs:XP_004280256	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Orcinus orca].	77.46	71	15	1	224	294	1	70	3e-25	106
rs:WP_028028815	hypothetical protein [Gemmobacter nectariphilus].	30.90	288	176	8	4	289	3	269	3e-25	112
rs:XP_002585935	hypothetical protein BRAFLDRAFT_289526 [Branchiostoma floridae].	52.83	106	50	0	188	293	10	115	3e-25	116
rs:WP_023059794	tetrahydrofolate dehydrogenase [Peptoniphilus sp. BV3AC2].	29.59	267	175	4	21	286	18	272	3e-25	112
rs:XP_006265976	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Alligator mississippiensis].	72.22	72	19	1	224	295	1	71	3e-25	106
rs:WP_017600069	hypothetical protein, partial [Nocardiopsis lucentensis].	42.36	144	72	3	149	292	1	133	4e-25	108
rs:WP_019034626	tetrahydrofolate dehydrogenase [Peptoniphilus lacrimalis].	29.12	261	173	5	15	274	21	270	4e-25	112
tr:A0A0A7P9I7_9BACT	SubName: Full=5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:AJA06589.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AJA06589.1}; EC=3.5.4.9 {ECO:0000313|EMBL:AJA06589.1};	29.37	286	176	7	6	291	4	263	5e-25	111
tr:A0A059LFX3_9CHLO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDD73227.1};	31.12	196	108	3	2	197	12	180	5e-25	112
tr:A0A059LFX3_9CHLO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDD73227.1};	38.39	112	53	2	195	290	262	373	3e-08	64.3
gp:CP007365_379	methylenetetrahydrofolate dehydrogenase [Salmonella enterica subsp. enterica serovar Enteritidis str.]	52.38	105	50	0	1	105	1	105	5e-25	107
tr:V7Z2B3_LACPN	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:ETC80483.1}; EC=1.5.1.5 {ECO:0000313|EMBL:ETC80483.1}; EC=3.5.4.9 {ECO:0000313|EMBL:ETC80483.1}; Flags: Fragment;	40.27	149	86	2	9	155	4	151	6e-25	108
rs:WP_043802183	methenyltetrahydrofolate cyclohydrolase [Deinococcus gobiensis].	30.45	289	179	9	6	290	8	278	7e-25	111
rs:WP_038816378	hypothetical protein, partial [Shigella dysenteriae].	53.40	103	48	0	1	103	1	103	8e-25	106
tr:D9UG08_STRS3	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EFL01166.1}; Flags: Fragment;	33.80	213	136	2	3	215	12	219	8e-25	111
rs:WP_046657139	hypothetical protein, partial [Escherichia coli].	53.40	103	48	0	1	103	1	103	8e-25	106
rs:WP_044008196	hypothetical protein, partial [Ketogulonicigenium vulgare].	35.82	201	117	3	92	291	12	201	9e-25	109
gp:BC065771_1	MTHFD2L protein [Homo sapiens]	76.06	71	16	1	224	294	1	70	1e-24	105
tr:W1P3P1_AMBTC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERN02176.1};	45.60	125	62	2	94	216	2	122	1e-24	107
rs:WP_034338501	methenyltetrahydrofolate cyclohydrolase, partial [Deinococcus misasensis].	27.72	285	190	6	6	288	4	274	1e-24	110
rs:XP_011157134	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like, partial [Solenopsis invicta].	61.18	85	31	1	208	292	1	83	1e-24	105
tr:X1VFU9_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_S19383 {ECO:0000313|EMBL:GAJ13361.1}; Flags: Fragment;	53.92	102	40	1	192	293	1	95	1e-24	105
rs:WP_026598414	hypothetical protein [Methylocystis sp. LW5].	31.65	278	170	5	2	277	6	265	1e-24	110
rs:XP_003481227	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Sus scrofa].	75.00	68	16	1	224	291	1	67	2e-24	105
tr:E3F2J9_KETVY	SubName: Full=FolD bifunctional protein {ECO:0000313|EMBL:ADO43179.1};	35.82	201	117	3	92	291	79	268	2e-24	110
tr:V6KUL9_STRRC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EST35885.1};	31.98	197	122	1	2	186	3	199	2e-24	108
rs:WP_024879602	hypothetical protein [Methylosinus sp. LW3].	31.65	278	170	5	2	277	6	265	2e-24	109
rs:WP_031083766	methenyltetrahydrofolate cyclohydrolase, partial [Streptomyces sp. NRRL WC-3549].	46.72	122	56	4	171	292	1	113	3e-24	105
rs:XP_785404	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Strongylocentrotus purpuratus].	33.99	203	125	4	3	200	61	259	3e-24	109
rs:WP_002880847	methylenetetrahydrofolate dehydrogenase [Mycoplasma alkalescens].	30.54	298	182	11	5	294	4	284	3e-24	109
tr:K2BZ18_9BACT	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKD78786.1};	41.09	129	65	2	163	291	1	118	4e-24	105
rs:XP_006375331	hypothetical protein POPTR_0014s07650g, partial [Populus trichocarpa].	31.83	289	126	8	2	286	1	222	5e-24	107
rs:XP_011672800	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Strongylocentrotus purpuratus].	33.99	203	125	4	3	200	61	259	5e-24	108
tr:T1DJE5_ANOAQ	SubName: Full=Putative c1-tetrahydrofolate synthase {ECO:0000313|EMBL:JAB00090.1}; Flags: Fragment;	51.92	104	50	0	188	291	6	109	8e-24	112
tr:A0A090VYK2_9FLAO	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:GAL69771.1}; EC=1.5.1.5 {ECO:0000313|EMBL:GAL69771.1}; EC=3.5.4.9 {ECO:0000313|EMBL:GAL69771.1};	70.59	68	20	0	224	291	1	68	1e-23	102
tr:H8GZI8_DEIGI	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	30.28	284	176	9	11	290	1	266	1e-23	107
tr:X1T0F0_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_S02695 {ECO:0000313|EMBL:GAI98663.1}; Flags: Fragment;	61.90	84	25	1	207	290	1	77	1e-23	102
rs:XP_010666366	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X2 [Beta vulgaris subsp. vulgaris].	50.00	104	52	0	188	291	176	279	1e-23	107
rs:XP_010666366	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X2 [Beta vulgaris subsp. vulgaris].	36.54	104	66	0	1	104	70	173	1e-13	79.0
rs:WP_042736418	hypothetical protein [Lachnospiraceae bacterium TWA4].	27.86	323	193	8	3	290	2	319	2e-23	107
rs:XP_007648859	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X2 [Cricetulus griseus].	33.81	210	92	3	11	214	1	169	2e-23	105
rs:XP_012339857	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Apis florea].	40.27	149	89	0	31	179	23	171	2e-23	104
tr:X1L609_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C01909 {ECO:0000313|EMBL:GAI01331.1}; Flags: Fragment;	40.71	140	82	1	6	144	1	140	2e-23	103
rs:WP_036824891	methylenetetrahydrofolate dehydrogenase [Photobacterium sanctipauli].	32.28	254	149	6	36	286	29	262	2e-23	106
rs:WP_007195762	methylenetetrahydrofolate dehydrogenase [Thiocapsa marina].	56.47	85	31	1	206	290	17	95	2e-23	102
rs:WP_044818284	hypothetical protein, partial [Escherichia coli].	42.06	126	68	1	20	145	20	140	2e-23	103
tr:A0A0C7CK34_9FUNG	SubName: Full=RMATCC62417_17723 protein {ECO:0000313|EMBL:CEG83855.1};	44.72	123	67	1	1	122	1	123	4e-23	102
tr:K1Z483_9BACT	SubName: Full=Bifunctional protein folD {ECO:0000313|EMBL:EKD44066.1}; Flags: Fragment;	38.81	134	71	3	159	292	1	123	5e-23	102
rs:WP_007462547	methylenetetrahydrofolate dehydrogenase [Photobacterium sp. AK15].	31.78	258	153	7	36	290	29	266	6e-23	105
tr:Q9XYB0_DROME	SubName: Full=PugilistDominant {ECO:0000313|EMBL:AAD29852.1}; Flags: Fragment;	36.93	176	107	3	3	174	4	179	6e-23	105
tr:X0UI90_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_L10538 {ECO:0000313|EMBL:GAF98996.1}; Flags: Fragment;	58.62	87	35	1	204	290	3	88	6e-23	100
tr:A0A0C4DG60_HUMAN	SubName: Full=Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|Ensembl:ENSP00000405692};	44.85	136	69	2	89	218	2	137	6e-23	102
tr:G4D5C9_9FIRM	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EGY79030.1}; EC=1.5.1.5 {ECO:0000313|EMBL:EGY79030.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EGY79030.1};	31.25	192	121	3	96	286	1	182	6e-23	103
rs:WP_042768104	methenyltetrahydrofolate cyclohydrolase, partial [Vibrio parahaemolyticus].	48.72	117	60	0	1	117	1	117	7e-23	101
rs:WP_031264329	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Streptococcus agalactiae].	55.67	97	37	2	197	293	1	91	7e-23	100
rs:WP_017707688	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Pseudomonas syringae].	47.58	124	64	1	1	124	1	123	8e-23	101
tr:X3X953_SALEN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AHS51126.1}; Flags: Fragment;	52.53	99	43	1	118	216	6	100	8e-23	100
tr:X7YBB6_MYCKA	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:EUA04126.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EUA04126.1};	40.00	125	75	0	36	160	1	125	9e-23	102
rs:WP_031261961	methenyltetrahydrofolate cyclohydrolase, partial [Curtobacterium sp. B18].	42.96	135	71	3	160	294	1	129	9e-23	101
tr:K2CJC2_9BACT	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	26.60	297	187	7	6	292	3	278	1e-22	105
rs:WP_019681961	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas aeruginosa].	45.61	114	62	0	1	114	1	114	1e-22	100
rs:WP_035348036	methenyltetrahydrofolate cyclohydrolase, partial [Acetobacter aceti].	41.41	128	75	0	3	130	4	131	1e-22	101
rs:WP_038836142	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas aeruginosa].	45.61	114	62	0	1	114	1	114	1e-22	100
tr:A0A090QNN2_9GAMM	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:GAL03429.1}; EC=1.5.1.5 {ECO:0000313|EMBL:GAL03429.1}; EC=3.5.4.9 {ECO:0000313|EMBL:GAL03429.1};	33.58	265	152	8	27	286	17	262	2e-22	104
tr:F4MXA4_YEREN	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CBX70462.1}; Flags: Fragment;	55.81	86	32	2	206	291	9	88	2e-22	99.8
tr:A6BAZ7_VIBPQ	SubName: Full=Fold bifunctional protein (Ppdc) {ECO:0000313|EMBL:EDM56656.1}; EC=1.5.1.5 {ECO:0000313|EMBL:EDM56656.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EDM56656.1}; Flags: Fragment;	44.83	145	77	2	1	142	1	145	2e-22	102
rs:WP_038338716	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [gamma proteobacterium SCGC AAA536-N21].	43.51	131	60	3	161	291	6	122	2e-22	100
tr:A0A059AFW9_EUCGR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KCW52290.1};	35.37	164	95	4	83	239	1	160	2e-22	102
rs:WP_035100237	hypothetical protein [Devosia sp. LC5].	30.82	279	175	5	13	289	6	268	2e-22	103
rs:XP_004673406	PREDICTED: LOW QUALITY PROTEIN: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like [Jaculus jaculus].	37.31	201	116	6	16	210	27	223	2e-22	103
rs:WP_022379131	bifunctional protein FolD [Cryptobacterium sp. CAG:338].	44.14	145	71	2	149	293	1	135	2e-22	100
tr:Q48977_MYCCA	SubName: Full=C1-THF synthase {ECO:0000313|EMBL:CAA83718.2};	41.74	115	67	0	73	187	3	117	2e-22	100
tr:A0A085F7E9_9RHIZ	RecName: Full=Bifunctional protein FolD {ECO:0000256|HAMAP-Rule:MF_01576};	30.82	279	175	5	13	289	10	272	2e-22	103
rs:WP_022252244	bifunctional protein FolD [Prevotella sp. CAG:386].	63.38	71	26	0	224	294	1	71	3e-22	98.6
rs:XP_012385833	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Dasypus novemcinctus].	39.87	153	77	5	145	291	17	160	3e-22	101
rs:XP_008479403	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Diaphorina citri].	33.90	177	79	1	3	179	28	166	3e-22	102
rs:XP_008479403	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Diaphorina citri].	69.23	39	12	0	255	293	169	207	2e-06	57.4
rs:XP_011478458	PREDICTED: uncharacterized protein LOC105354893 [Oryzias latipes].	39.79	191	104	5	15	200	100	284	4e-22	107
tr:W1NX47_AMBTC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERN02177.1};	59.46	74	30	0	220	293	8	81	4e-22	98.6
rs:WP_044115860	methenyltetrahydrofolate cyclohydrolase, partial [Aggregatibacter actinomycetemcomitans].	41.90	105	61	0	1	105	1	105	4e-22	99.0
rs:WP_028720523	hypothetical protein, partial [Paracoccus yeei].	45.19	135	73	1	1	135	1	134	5e-22	99.8
rs:WP_035173467	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Lactobacillus equicursoris].	44.92	118	54	2	174	291	2	108	5e-22	99.0
rs:XP_005842486	hypothetical protein GUITHDRAFT_52912, partial [Guillardia theta CCMP2712].	33.33	273	155	10	28	284	1	262	6e-22	102
rs:WP_022331542	bifunctional protein FolD [Firmicutes bacterium CAG:345].	32.40	250	144	8	39	286	29	255	6e-22	102
tr:K7KDB4_SOYBN	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:GLYMA03G10355.1};	39.29	140	78	3	103	239	2	137	6e-22	100
rs:WP_043653158	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Nocardia thailandica].	38.27	162	96	1	34	195	33	190	7e-22	101
rs:WP_031511843	methenyltetrahydrofolate cyclohydrolase, partial [Corynebacterium crenatum].	46.28	121	55	3	171	291	1	111	7e-22	99.0
rs:WP_036315460	methenyltetrahydrofolate cyclohydrolase, partial [Microbacterium sp. B24].	38.71	155	84	5	1	148	1	151	7e-22	99.8
tr:K2CSZ3_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKD96235.1};	25.94	293	193	6	5	297	3	271	7e-22	102
tr:K1QNC8_CRAGI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKC35423.1};	45.22	115	63	0	1	115	612	726	8e-22	106
rs:WP_039120936	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Lactobacillus ruminis].	51.46	103	44	1	194	296	1	97	9e-22	97.8
tr:X1SZY8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_L05189 {ECO:0000313|EMBL:GAI84711.1}; Flags: Fragment;	42.74	117	63	1	119	235	1	113	1e-21	98.6
rs:WP_019794098	hypothetical protein, partial [Streptococcus sobrinus].	45.95	111	60	0	1	111	1	111	1e-21	98.2
rs:WP_031133720	MULTISPECIES: 5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Streptomyces].	41.27	126	60	2	168	293	1	112	1e-21	98.2
rs:WP_021993205	bifunctional protein FolD [Prevotella sp. CAG:487].	63.38	71	26	0	224	294	1	71	1e-21	96.7
rs:XP_005068142	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2-like [Mesocricetus auratus].	33.96	212	98	3	46	257	53	222	2e-21	101
tr:F6YN90_MACMU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000024401};	28.33	293	168	9	3	291	31	285	2e-21	102
rs:WP_031364327	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Burkholderia sordidicola].	38.35	133	68	2	160	292	1	119	2e-21	97.8
tr:G3I474_CRIGR	RecName: Full=C-X-C motif chemokine {ECO:0000256|RuleBase:RU361149};	33.64	220	89	4	3	216	100	268	2e-21	101
rs:WP_022901848	methylenetetrahydrofolate dehydrogenase [Humibacter albus].	29.88	328	170	11	1	292	1	304	2e-21	101
rs:WP_036640735	methenyltetrahydrofolate cyclohydrolase, partial [Paenirhodobacter enshiensis].	49.52	105	53	0	75	179	13	117	2e-21	97.4
rs:WP_031699670	methenyltetrahydrofolate cyclohydrolase, partial [Mycobacterium tuberculosis].	41.48	135	69	3	157	291	1	125	3e-21	97.4
rs:WP_017053607	hypothetical protein [Vibrio genomosp. F6].	32.43	259	150	7	36	290	29	266	3e-21	100
rs:WP_005625708	tetrahydrofolate dehydrogenase, partial [Mycobacterium hassiacum].	49.14	116	50	4	171	286	3	109	3e-21	97.1
rs:WP_021948957	bifunctional protein FolD [Prevotella sp. CAG:1124].	63.38	71	26	0	224	294	1	71	3e-21	95.9
tr:K2BT01_9BACT	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKD65394.1};	30.59	219	121	4	87	293	2	201	3e-21	99.4
tr:I2CQW0_9STRA	SubName: Full=Bifunctional protein {ECO:0000313|EMBL:AFJ69293.1}; Flags: Fragment;	27.05	329	186	9	5	289	85	403	3e-21	103
tr:K0AZ69_CLOA9	SubName: Full=Bifunctional 5,10-methylenetetrahydrofolate dehydrogenase (NADP+/NAD+)/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:AFS77990.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AFS77990.1}; EC=3.5.4.9 {ECO:0000313|EMBL:AFS77990.1};	29.62	287	178	8	6	286	4	272	3e-21	100
rs:WP_039943033	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Lactobacillus equicursoris].	46.55	116	50	2	176	291	1	104	3e-21	96.7
rs:WP_026024172	hypothetical protein, partial [Enterovibrio norvegicus].	62.79	86	29	2	207	292	1	83	4e-21	95.9
tr:T1BQH4_9ZZZZ	SubName: Full=Bifunctional protein: methylenetetrahydrofolate dehydrogenase + methenyltetrahydrofolate cyclohydrolase, FolD {ECO:0000313|EMBL:EQD56260.1}; Flags: Fragment;	45.32	139	68	2	152	290	2	132	5e-21	97.1
tr:N6U9X4_9RHIZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:ENN89364.1};	42.54	134	74	2	36	166	18	151	5e-21	98.6
rs:XP_009596185	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X2 [Nicotiana tomentosiformis].	35.00	160	100	1	135	294	5	160	5e-21	97.8
tr:X1P9W2_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S21831 {ECO:0000313|EMBL:GAI53087.1}; Flags: Fragment;	50.51	99	42	1	191	289	2	93	6e-21	95.5
rs:WP_022328126	bifunctional protein FolD [Prevotella sp. CAG:732].	61.97	71	27	0	224	294	1	71	8e-21	94.4
tr:A0A0B8Q173_9VIBR	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:GAM73240.1}; EC=1.5.1.5 {ECO:0000313|EMBL:GAM73240.1}; EC=3.5.4.9 {ECO:0000313|EMBL:GAM73240.1};	54.65	86	33	2	206	291	3	82	8e-21	94.7
tr:K0NVU4_9LACO	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:CCK84801.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CCK84801.1};	46.49	114	49	2	178	291	1	102	9e-21	95.5
tr:S8BVE7_9LAMI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPS58565.1}; Flags: Fragment;	58.11	74	31	0	220	293	3	76	9e-21	94.7
tr:A0A0A9I5S0_ARUDO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:JAE44387.1};	58.67	75	31	0	219	293	2	76	9e-21	94.7
tr:S4RW96_PETMA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPMAP00000009486}; Flags: Fragment;	52.22	90	43	0	207	296	5	94	1e-20	102
rs:XP_008295304	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like [Stegastes partitus].	58.90	73	30	0	219	291	1	73	1e-20	94.4
rs:WP_044623444	methylenetetrahydrofolate dehydrogenase [Photobacterium gaetbulicola].	33.33	258	141	9	36	286	29	262	1e-20	98.6
rs:WP_016678943	hypothetical protein, partial [Yersinia pestis].	54.76	84	32	2	208	291	1	78	2e-20	94.0
rs:WP_030750727	hypothetical protein, partial [Streptomyces sp. NRRL F-5135].	32.09	215	125	6	79	276	12	222	2e-20	97.8
rs:WP_024252155	hypothetical protein, partial [Escherichia coli].	51.55	97	47	0	1	97	1	97	2e-20	94.0
rs:WP_005838042	FolD protein [Eubacterium saphenum].	25.73	307	192	8	6	292	3	293	3e-20	98.2
tr:A0A060WHW7_ONCMY	SubName: Full=Oncorhynchus mykiss genomic scaffold, scaffold_289 {ECO:0000313|EMBL:CDQ66868.1};	57.33	75	32	0	219	293	1	75	3e-20	95.9
rs:WP_043726805	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Nocardia asiatica].	36.42	151	96	0	29	179	28	178	3e-20	96.3
tr:Q5WN01_ORYSJ	SubName: Full=Putative uncharacterized protein P0001A07.7 {ECO:0000313|EMBL:AAV32200.1};	58.11	74	31	0	220	293	19	92	3e-20	93.6
tr:X0SPS6_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_C00825 {ECO:0000313|EMBL:GAF83093.1}; Flags: Fragment;	55.95	84	32	1	213	291	1	84	3e-20	93.6
rs:XP_010032800	PREDICTED: bifunctional protein FolD 1, mitochondrial-like [Eucalyptus grandis].	34.15	164	97	4	83	239	1	160	3e-20	95.5
rs:XP_011093253	PREDICTED: bifunctional protein FolD 4, chloroplastic-like, partial [Sesamum indicum].	42.74	124	60	3	170	292	1	114	4e-20	94.0
rs:WP_036318450	methenyltetrahydrofolate cyclohydrolase, partial [Microbacterium sp. B24].	46.73	107	55	2	187	293	3	107	4e-20	93.6
rs:WP_039464023	methylenetetrahydrofolate dehydrogenase [Photobacterium gaetbulicola].	31.76	255	149	7	36	286	29	262	5e-20	97.1
rs:WP_025957794	hypothetical protein, partial [Prochlorococcus sp. scB245a_518J7].	49.07	108	52	2	187	293	1	106	5e-20	93.6
rs:WP_019174750	hypothetical protein [Brevibacterium massiliense].	27.18	309	196	10	1	291	1	298	5e-20	97.4
tr:G2RRA3_BACME	SubName: Full=Strongly bifunctional 5,10 methylene-tetrahydrofolate dehydrogenase/cyclohydrolase FolD {ECO:0000313|EMBL:AEN90039.1};	39.20	125	75	1	1	125	1	124	7e-20	94.0
rs:XP_001864655	methyl enetetrahydrofolate dehydrogenase [Culex quinquefasciatus].	55.29	85	38	0	207	291	13	97	8e-20	100
tr:G3RRI9_GORGO	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000018413}; Flags: Fragment;	31.35	303	178	9	5	295	39	323	9e-20	97.1
rs:WP_025948229	hypothetical protein, partial [Prochlorococcus sp. scB243_495I8].	48.04	102	49	1	138	239	1	98	9e-20	92.4
rs:WP_036746009	hypothetical protein, partial [Peptostreptococcus anaerobius].	29.57	257	163	8	38	288	1	245	1e-19	95.9
rs:XP_004029774	hypothetical protein IMG5_173280 [Ichthyophthirius multifiliis].	33.77	151	93	3	147	297	1	144	1e-19	93.6
tr:Q41938_ARATH	SubName: Full=NAD-dep methylenetetrahydrofolate dehydrogenase cyclohydrolase {ECO:0000313|EMBL:CAA79072.1}; Flags: Fragment;	59.42	69	28	0	223	291	1	69	1e-19	91.3
tr:X0SY58_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S02783 {ECO:0000313|EMBL:GAF86143.1}; Flags: Fragment;	44.17	120	63	1	4	123	2	117	2e-19	92.4
rs:WP_016369665	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Lactobacillus paracasei].	53.68	95	38	1	197	291	3	91	2e-19	91.7
tr:S9VLU3_9TRYP	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:EPY41858.1};	32.49	237	95	8	114	288	2	235	2e-19	95.5
tr:K1SMT0_9ZZZZ	SubName: Full=Protein containing Tetrahydrofolate dehydrogenase/cyclohydrolase domain protein {ECO:0000313|EMBL:EKC61947.1}; EC=6.3.4.3 {ECO:0000313|EMBL:EKC61947.1};	60.81	74	23	2	219	292	1	68	2e-19	90.5
tr:G5MEV0_SALET	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EHC53761.1};	58.75	80	27	2	209	288	1	74	3e-19	90.5
rs:WP_041701957	hypothetical protein, partial [Gottschalkia acidurici].	31.58	171	102	3	6	175	4	160	6e-19	91.7
tr:A0A0D3DSR9_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo8g082770.1};	55.41	74	33	0	219	292	1	74	8e-19	89.0
rs:WP_039189461	methenyltetrahydrofolate cyclohydrolase, partial [Leisingera sp. ANG-M6].	52.33	86	38	2	207	292	2	84	9e-19	89.4
rs:WP_037067448	methenyltetrahydrofolate cyclohydrolase, partial [Rhizobium leguminosarum].	42.34	111	64	0	4	114	3	113	1e-18	89.7
rs:XP_009596184	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X1 [Nicotiana tomentosiformis].	35.00	160	99	2	135	293	5	160	1e-18	91.7
tr:S6V9H1_PSESF	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EPN47735.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EPN47735.1}; Flags: Fragment;	55.00	80	33	1	215	294	1	77	1e-18	89.0
tr:K2FV77_9BACT	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKE14800.1};	26.58	301	187	8	5	290	2	283	1e-18	93.2
tr:R4PUZ2_9BACT	SubName: Full=Putative Methylenetetrahydrofolate dehydrogenase (NADP(+)) {ECO:0000313|EMBL:AGL61995.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AGL61995.1};	30.42	240	143	7	50	289	50	265	2e-18	92.4
tr:G5DYJ0_9PIPI	SubName: Full=Putative methylenetetrahydrofolate dehydrogenase 2 {ECO:0000313|EMBL:AEQ16599.1}; Flags: Fragment;	39.86	143	50	3	161	297	14	126	2e-18	89.4
rs:WP_032620814	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas syringae].	56.58	76	30	1	219	294	1	73	2e-18	88.2
tr:A0A061AR49_CYBFA	SubName: Full=CYFA0S01e08460g1_1 {ECO:0000313|EMBL:CDR37207.1};	26.12	291	157	10	32	286	36	304	3e-18	92.4
rs:WP_041893867	methenyltetrahydrofolate cyclohydrolase, partial [Verrucomicrobia bacterium SCGC AAA164-L15].	65.00	60	21	0	231	290	1	60	3e-18	87.0
tr:A0A094LFP2_9AVES	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFZ68222.1}; Flags: Fragment;	45.00	100	55	0	3	102	5	104	3e-18	88.2
tr:X1GX06_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S01277 {ECO:0000313|EMBL:GAH61697.1};	56.25	80	22	1	224	290	1	80	4e-18	87.4
tr:T1ALS3_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EQD58327.1}; Flags: Fragment;	50.54	93	42	1	147	239	1	89	4e-18	87.4
tr:F3JQS7_PSESX	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EGH74200.1}; EC=1.5.1.5 {ECO:0000313|EMBL:EGH74200.1};	55.26	76	31	1	219	294	1	73	5e-18	87.0
tr:K6KH63_KLEOX	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKP29618.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EKP29618.1}; Flags: Fragment;	52.22	90	43	0	1	90	1	90	6e-18	87.0
rs:WP_022364292	bifunctional protein FolD [Clostridium sp. CAG:505].	60.26	78	25	2	213	290	3	74	6e-18	86.7
rs:WP_037060987	methenyltetrahydrofolate cyclohydrolase, partial [Rhizobium leguminosarum].	41.28	109	64	0	5	113	4	112	7e-18	87.4
tr:W2TFH6_NECAM	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein {ECO:0000313|EMBL:ETN80785.1}; Flags: Fragment;	37.89	161	91	4	1	154	1	159	7e-18	88.6
rs:WP_044813203	hypothetical protein, partial [Escherichia coli].	50.00	94	47	0	1	94	1	94	8e-18	87.0
tr:T0EB89_CLOSO	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EPZ60928.1};	40.50	121	62	3	170	290	2	112	8e-18	87.4
rs:XP_003392014	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like, partial [Amphimedon queenslandica].	43.27	104	59	0	4	107	18	121	9e-18	87.4
tr:S6UQL1_PSESF	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EPN57798.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EPN57798.1}; Flags: Fragment;	57.33	75	29	1	220	294	1	72	1e-17	86.3
tr:K1TXF0_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKC63901.1};	65.67	67	17	2	224	290	1	61	1e-17	85.5
rs:WP_019192799	hypothetical protein [Anaerococcus pacaensis].	26.01	273	186	5	14	286	4	260	1e-17	89.7
rs:WP_022492848	bifunctional protein FolD [Clostridium sp. CAG:628].	26.05	238	146	5	47	284	35	242	2e-17	89.4
tr:Q71IF6_LACDL	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:AAQ06981.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AAQ06981.1}; Flags: Fragment;	46.67	90	44	1	150	239	1	86	2e-17	85.9
tr:A0A091QVW3_MERNU	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFQ31099.1}; Flags: Fragment;	46.00	100	54	0	3	102	4	103	2e-17	85.9
rs:WP_002836174	methylenetetrahydrofolate dehydrogenase [Finegoldia magna].	28.93	242	152	8	19	255	9	235	2e-17	89.4
tr:X1BMG7_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S12566 {ECO:0000313|EMBL:GAG96190.1}; Flags: Fragment;	46.88	96	51	0	54	149	7	102	2e-17	85.9
tr:K1XS50_9BACT	SubName: Full=Bifunctional protein folD {ECO:0000313|EMBL:EKD23178.1};	28.62	304	172	11	8	288	5	286	2e-17	89.4
tr:H1DB97_9FUSO	SubName: Full=FolD protein {ECO:0000313|EMBL:EHO17894.1};	57.14	77	27	2	212	288	1	71	3e-17	85.1
tr:T1AKR1_9ZZZZ	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase domain protein {ECO:0000313|EMBL:EQD41354.1}; EC=6.3.4.3 {ECO:0000313|EMBL:EQD41354.1}; Flags: Fragment;	43.27	104	59	0	188	291	28	131	3e-17	86.7
tr:V5GLQ7_ANOGL	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:JAB62532.1}; Flags: Fragment;	60.00	75	28	1	215	289	82	154	4e-17	86.3
tr:V5GLQ7_ANOGL	SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|EMBL:JAB62532.1}; Flags: Fragment;	40.32	62	37	0	2	63	22	83	8e-07	57.4
rs:WP_010200436	methylenetetrahydrofolate dehydrogenase, partial [Pseudomonas amygdali].	60.00	70	25	1	222	291	1	67	5e-17	84.3
tr:W1HXB2_KLEPN	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:CDL62246.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CDL62246.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CDL62246.1};	54.55	77	29	2	215	291	2	72	5e-17	84.0
tr:T1B1J4_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP(+)) {ECO:0000313|EMBL:EQD63712.1}; Flags: Fragment;	45.83	96	42	2	163	258	1	86	5e-17	84.3
rs:WP_038818823	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas syringae].	59.42	69	25	1	226	294	1	66	5e-17	84.0
tr:A0A093Q8Z1_9PASS	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFW85448.1}; Flags: Fragment;	45.00	100	55	0	3	102	4	103	5e-17	84.7
tr:A0A0A9YB98_LYGHE	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:JAG30357.1}; Flags: Fragment;	36.07	122	70	2	141	262	7	120	6e-17	85.9
rs:WP_036744533	tetrahydrofolate dehydrogenase, partial [Peptoniphilus sp. oral taxon 836].	32.42	182	111	5	94	274	1	171	6e-17	86.7
tr:I1E8F5_AMPQE	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:PAC:15699790}; Flags: Fragment;	43.27	104	59	0	4	107	95	198	7e-17	86.7
rs:WP_007637670	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Rhizobium sp. CCGE 510].	41.03	117	69	0	2	118	3	119	7e-17	84.7
rs:WP_044819758	hypothetical protein [Escherichia coli].	50.00	86	39	1	118	203	36	117	8e-17	84.7
rs:XP_451354	hypothetical protein [Kluyveromyces lactis NRRL Y-1140].	26.78	295	153	12	33	286	37	309	8e-17	88.2
tr:F3J9H7_PSEAP	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EGH81053.1}; EC=1.5.1.5 {ECO:0000313|EMBL:EGH81053.1}; Flags: Fragment;	47.57	103	53	1	1	103	1	102	9e-17	84.0
tr:A0A091UE26_PHORB	SubName: Full=Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|EMBL:KFQ88974.1}; Flags: Fragment;	45.00	100	55	0	3	102	5	104	1e-16	84.0
tr:G1LPS9_AILME	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAMEP00000009059}; Flags: Fragment;	52.83	106	43	5	190	293	96	196	1e-16	86.7
tr:G1LPS9_AILME	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAMEP00000009059}; Flags: Fragment;	38.27	81	50	0	3	83	32	112	8e-09	63.9
rs:WP_002838436	methylenetetrahydrofolate dehydrogenase [Finegoldia magna].	28.40	243	154	8	18	255	8	235	1e-16	87.0
tr:I3MU17_SPETR	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSTOP00000015612}; Flags: Fragment;	43.22	118	61	2	104	215	2	119	1e-16	84.0
rs:WP_039453860	methenyltetrahydrofolate cyclohydrolase, partial [Xanthomonas vasicola].	59.15	71	23	1	219	289	1	65	1e-16	82.8
rs:WP_022350025	bifunctional protein FolD [Collinsella sp. CAG:398].	31.16	199	131	3	3	200	2	195	1e-16	86.7
tr:X1J3B3_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S23844 {ECO:0000313|EMBL:GAH89191.1}; Flags: Fragment;	54.43	79	29	1	215	293	2	73	1e-16	82.8
rs:XP_011275142	Methylenetetrahydrofolate dehydrogenase [NAD+] [Wickerhamomyces ciferrii].	24.92	309	173	10	21	292	21	307	1e-16	87.4
rs:WP_001070306	hypothetical protein, partial [Leptospira interrogans].	38.24	102	63	0	1	102	1	102	1e-16	83.6
rs:WP_002839362	methylenetetrahydrofolate dehydrogenase [Finegoldia magna].	28.51	242	153	8	19	255	9	235	2e-16	86.7
tr:G5QF09_SALRU	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EHC93985.1}; Flags: Fragment;	48.96	96	39	3	168	263	1	86	2e-16	82.8
rs:WP_046466349	methenyltetrahydrofolate cyclohydrolase, partial [Staphylococcus equorum].	56.41	78	28	1	213	290	1	72	2e-16	82.4
tr:A0A0D2MAV0_9CHLO	SubName: Full=Strain SAG 48.87 unplaced genomic scaffold scaffold05384, whole genome shotgun sequence {ECO:0000313|EMBL:KIY92465.1}; EC=6.3.4.3 {ECO:0000313|EMBL:KIY92465.1};	50.67	75	37	0	219	293	1	75	2e-16	83.6
rs:WP_031721456	methenyltetrahydrofolate cyclohydrolase, partial [Mycobacterium tuberculosis].	42.98	114	55	3	178	291	3	106	2e-16	83.2
tr:A0A0A8KZ75_9SACH	SubName: Full=WGS project CCBQ000000000 data, contig 00107 {ECO:0000313|EMBL:CDO91883.1};	27.04	307	158	13	21	286	28	309	2e-16	87.0
rs:WP_010932401	methylenetetrahydrofolate dehydrogenase [Chlorobaculum tepidum].	25.55	317	170	12	4	286	2	286	3e-16	86.3
tr:A0A0D2LT91_9CHLO	SubName: Full=Strain SAG 48.87 unplaced genomic scaffold scaffold04955, whole genome shotgun sequence {ECO:0000313|EMBL:KIY92951.1}; EC=3.5.4.9 {ECO:0000313|EMBL:KIY92951.1}; Flags: Fragment;	52.00	75	36	0	219	293	1	75	3e-16	84.7
tr:K2DRV4_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKD96328.1};	27.87	287	182	8	4	286	2	267	3e-16	85.9
rs:WP_029978020	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Prochlorococcus sp. scB241_529J16].	50.59	85	41	1	209	293	1	84	4e-16	82.0
tr:A0A0C7MYU1_9SACH	SubName: Full=LALA0S01e17722g1_1 {ECO:0000313|EMBL:CEP60733.1};	26.37	311	166	10	17	286	20	308	4e-16	86.3
rs:WP_040018537	methenyltetrahydrofolate cyclohydrolase, partial [Xanthomonas axonopodis].	43.48	115	65	0	4	118	13	127	4e-16	82.8
rs:XP_003673282	hypothetical protein NCAS_0A03350 [Naumovozyma castellii CBS 4309].	25.68	296	157	11	32	286	33	306	4e-16	86.3
tr:A0A075FYE1_9ARCH	SubName: Full=Methylenetetrahydrofolate dehydrogenase (FolD) {ECO:0000313|EMBL:AIE94526.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AIE94526.1};	40.00	100	56	1	101	200	1	96	4e-16	82.0
tr:A0A0D3AEA9_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo1g139450.1};	56.92	65	28	0	227	291	57	121	5e-16	82.8
rs:WP_044573546	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Saccharopolyspora spinosa].	44.90	98	48	1	195	292	1	92	5e-16	81.6
tr:X1GIJ2_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_L04711 {ECO:0000313|EMBL:GAH41434.1}; Flags: Fragment;	38.40	125	75	1	3	125	2	126	5e-16	82.8
tr:S8C737_9LAMI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPS62610.1}; Flags: Fragment;	45.10	102	56	0	2	103	7	108	5e-16	82.0
rs:WP_032356506	hypothetical protein, partial [Shigella flexneri].	49.44	89	45	0	1	89	1	89	5e-16	81.6
tr:A0A0D3UP44_YEASX	SubName: Full=Mtd1p {ECO:0000313|EMBL:AJS51181.1};	25.70	323	176	14	6	286	8	308	5e-16	85.9
tr:F3KHD9_9GAMM	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EGG98216.1};	51.32	76	36	1	219	293	1	76	5e-16	81.3
tr:X7Y852_MYCKA	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EUA02693.1};	44.55	101	48	2	191	291	2	94	6e-16	81.6
rs:WP_030431457	hypothetical protein, partial [Allokutzneria albata].	30.05	213	128	5	79	287	1	196	6e-16	84.3
tr:X1P258_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S15488 {ECO:0000313|EMBL:GAI36516.1};	59.09	66	20	1	225	290	1	59	7e-16	80.5
tr:A0A0D3UT52_YEASX	SubName: Full=Mtd1p {ECO:0000313|EMBL:AJS53273.1};	26.23	324	173	14	6	286	8	308	8e-16	85.5
rs:WP_022882000	methylenetetrahydrofolate dehydrogenase [Gryllotalpicola ginsengisoli].	26.91	327	181	11	1	292	1	304	1e-15	84.7
rs:XP_003875490	methylenetetrahydrofolate dehydrogenase-like protein [Leishmania mexicana MHOM/GT/2001/U1103].	37.06	143	74	4	161	290	277	416	1e-15	86.7
rs:XP_003875490	methylenetetrahydrofolate dehydrogenase-like protein [Leishmania mexicana MHOM/GT/2001/U1103].	36.09	133	81	1	2	134	13	141	2e-07	61.6
sp:MTD1_YEAST	RecName: Full=Methylenetetrahydrofolate dehydrogenase [NAD(+)]; EC=1.5.1.15;	26.23	324	173	14	6	286	8	308	1e-15	85.1
tr:A0A0D3U319_YEASX	SubName: Full=Mtd1p {ECO:0000313|EMBL:AJS43731.1};	26.23	324	173	14	6	286	8	308	1e-15	84.7
tr:X3WYJ3_SALEN	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:AHS53584.1}; Flags: Fragment;	51.65	91	36	1	11	101	1	83	1e-15	80.1
tr:A0A0B4BF84_9LACO	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:KIC05602.1};	54.67	75	28	1	219	293	1	69	1e-15	79.7
tr:A0A0D3U9F8_YEASX	SubName: Full=Mtd1p {ECO:0000313|EMBL:AJS46744.1};	26.23	324	173	14	6	286	8	308	1e-15	84.7
gp:CP007319_333	methylenetetrahydrofolate dehydrogenase [Salmonella enterica subsp. enterica serovar Enteritidis str.]	47.25	91	48	0	1	91	1	91	1e-15	80.5
tr:W0T5E4_KLUMA	SubName: Full=Methylenetetrahydrofolate dehydrogenase [NAD+] {ECO:0000313|EMBL:BAO38041.1};	24.92	317	175	11	11	286	15	309	2e-15	84.7
tr:A0A0D3SZ46_YEASX	SubName: Full=Mtd1p {ECO:0000313|EMBL:AJS30904.1};	25.93	324	174	14	6	286	8	308	2e-15	84.3
rs:WP_012501939	methylenetetrahydrofolate dehydrogenase [Chlorobaculum parvum].	26.20	313	169	11	6	286	4	286	2e-15	84.0
tr:D8FKV2_9FIRM	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EFK38292.1};	31.11	180	112	5	96	274	1	169	2e-15	82.4
tr:A0A090BDA8_KLUMA	SubName: Full=Methylenetetrahydrofolate dehydrogenase [NAD+] {ECO:0000313|EMBL:BAP69612.1};	24.92	317	175	11	11	286	15	309	2e-15	84.3
rs:WP_022004679	bifunctional protein FolD [Firmicutes bacterium CAG:194].	57.35	68	22	2	219	286	1	61	2e-15	79.3
tr:F6Q8S5_MACMU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000020402}; Flags: Fragment;	42.74	117	61	2	104	214	2	118	2e-15	80.9
tr:W1YUJ9_9ZZZZ	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:ETJ44834.1}; Flags: Fragment;	54.17	72	33	0	78	149	1	72	2e-15	79.3
tr:A0A098VYG6_9MICR	SubName: Full=Bifunctional protein FolD domain-containing protein {ECO:0000313|EMBL:KGG52806.1};	46.67	90	42	2	205	293	1	85	3e-15	79.7
tr:X1DGD2_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_C04265 {ECO:0000313|EMBL:GAH19252.1}; Flags: Fragment;	43.43	99	56	0	1	99	1	99	3e-15	79.7
rs:WP_022413969	methenyltetrahydrofolate cyclohydrolase [Clostridium sp. CAG:288].	30.30	198	118	5	89	284	78	257	4e-15	82.8
rs:WP_044380899	methenyltetrahydrofolate cyclohydrolase, partial [Escherichia coli].	57.53	73	25	2	225	297	1	67	4e-15	78.2
rs:WP_031625085	hypothetical protein, partial [Salmonella enterica].	48.28	87	45	0	1	87	1	87	5e-15	78.6
tr:F3CGV4_PSESG	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EGH18496.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EGH18496.1}; Flags: Fragment;	52.11	71	28	1	206	276	1	65	6e-15	77.8
tr:A0A0B4HK67_9HYPO	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP(+)) {ECO:0000313|EMBL:KID90321.1};	27.02	285	176	11	19	290	11	276	7e-15	82.4
tr:K2FTJ3_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKE21109.1}; Flags: Fragment;	37.78	135	74	4	159	292	20	145	7e-15	80.1
rs:XP_002554956	KLTH0F17754p [Lachancea thermotolerans].	25.87	317	172	11	11	286	14	308	7e-15	82.8
tr:T1C1U5_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP(+)) {ECO:0000313|EMBL:EQD79446.1}; Flags: Fragment;	40.20	102	61	0	3	104	2	103	8e-15	78.6
tr:W2TGT6_NECAM	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:ETN80784.1};	58.82	68	24	2	220	285	24	89	9e-15	78.6
rs:XP_003686778	hypothetical protein TPHA_0H01380 [Tetrapisispora phaffii CBS 4417].	26.18	317	171	12	11	286	16	310	9e-15	82.4
tr:F3MLX1_LACHE	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EGF36853.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EGF36853.1};	57.97	69	22	1	224	292	1	62	1e-14	77.4
rs:WP_037134840	methenyltetrahydrofolate cyclohydrolase, partial [Rhizobium leucaenae].	56.34	71	30	1	223	292	1	71	1e-14	77.4
rs:XP_003958581	hypothetical protein KAFR_0H00370 [Kazachstania africana CBS 2517].	25.24	317	174	12	11	286	16	310	1e-14	82.0
rs:WP_044695391	methenyltetrahydrofolate cyclohydrolase, partial [Escherichia coli].	61.54	65	19	2	225	289	2	60	1e-14	77.0
rs:WP_028750435	hypothetical protein, partial [Rhizobium leucaenae].	56.34	71	30	1	223	292	1	71	1e-14	77.4
rs:XP_011104378	mtd1p [Saccharomyces arboricola H-6].	25.08	323	178	14	6	286	8	308	1e-14	82.0
tr:A0A090R011_9GAMM	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:GAL07439.1}; EC=1.5.1.5 {ECO:0000313|EMBL:GAL07439.1}; EC=3.5.4.9 {ECO:0000313|EMBL:GAL07439.1};	45.00	80	40	1	147	226	1	76	1e-14	77.4
rs:XP_459473	DEHA2E03366p [Debaryomyces hansenii CBS767].	25.00	292	158	11	34	286	36	305	2e-14	81.6
rs:WP_009848741	methylenetetrahydrofolate dehydrogenase, partial [Vibrio sp. MED222].	46.74	92	49	0	1	92	1	92	2e-14	77.0
tr:B5GAQ6_STRSH	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EDY43402.2};	29.55	247	138	9	46	286	55	271	2e-14	81.6
tr:H0GXT1_SACCK	SubName: Full=Mtd1p {ECO:0000313|EMBL:EHN01366.1};	25.39	323	177	14	6	286	8	308	2e-14	81.3
rs:WP_004818283	hypothetical protein [Anaerococcus hydrogenalis].	24.81	262	176	8	28	287	20	262	2e-14	80.5
rs:WP_037221092	methenyltetrahydrofolate cyclohydrolase, partial [Rhizobium sp. YR060].	40.78	103	61	0	5	107	4	106	2e-14	77.4
rs:WP_006793880	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Alteromonadales bacterium TW-7].	57.14	70	24	2	222	291	1	64	2e-14	76.3
tr:X1AP06_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S00307 {ECO:0000313|EMBL:GAG84434.1}; Flags: Fragment;	38.32	107	66	0	1	107	1	107	2e-14	77.4
tr:J7RXD8_KAZNA	SubName: Full=KNAG0C06490 protein {ECO:0000313|EMBL:CCK69742.1};	27.56	312	182	12	11	290	14	313	2e-14	81.3
tr:A0A0B4FRL0_9HYPO	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP(+)) {ECO:0000313|EMBL:KID76850.1}; Flags: Fragment;	26.50	283	176	11	21	290	13	276	2e-14	80.9
rs:XP_008384491	PREDICTED: bifunctional protein FolD 2-like [Malus domestica].	34.03	144	80	3	123	256	20	158	2e-14	78.6
rs:XP_003667721	hypothetical protein NDAI_0A03210 [Naumovozyma dairenensis CBS 421].	26.90	316	169	12	19	293	25	319	2e-14	81.3
tr:F3MLX7_LACHE	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EGF36680.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EGF36680.1}; Flags: Fragment;	35.54	121	77	1	3	123	2	121	2e-14	77.8
tr:G9NA59_HYPVG	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHK16825.1};	26.30	327	172	14	2	284	9	310	3e-14	81.3
rs:WP_040396976	hypothetical protein [Anaerococcus senegalensis].	24.51	253	174	5	38	289	28	264	3e-14	80.1
tr:J5MRJ4_PASMD	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EJS85457.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EJS85457.1}; Flags: Fragment;	55.56	72	25	2	222	293	2	66	3e-14	76.3
rs:WP_043490587	hypothetical protein, partial [Streptomyces bingchenggensis].	27.76	281	166	10	19	286	18	274	3e-14	80.5
tr:G1TFB6_RABIT	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOCUP00000015606};	40.22	92	55	0	11	102	1	92	3e-14	77.0
tr:I4MSZ2_9BURK	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EIK92332.1};	50.00	76	36	1	220	295	1	74	3e-14	76.3
tr:J6CLC8_PASMD	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EJS86138.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EJS86138.1}; Flags: Fragment;	39.76	83	50	0	1	83	1	83	3e-14	76.3
rs:XP_003857113	methylenetetrahydrofolate dehydrogenase (NAD(+)) [Zymoseptoria tritici IPO323].	27.05	281	146	12	32	273	35	295	4e-14	80.9
rs:WP_036325050	hypothetical protein [Microbispora sp. ATCC PTA-5024].	35.29	119	77	0	61	179	1	119	4e-14	77.8
rs:WP_031988684	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Acinetobacter baumannii].	36.97	119	73	2	5	122	2	119	4e-14	77.0
rs:XP_010129516	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like, partial [Buceros rhinoceros silvestris].	41.94	124	62	5	101	214	7	130	4e-14	77.4
tr:T0YT99_9ZZZZ	SubName: Full=5,10-methylene-tetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EQD36403.1}; Flags: Fragment;	36.75	117	63	2	174	290	1	106	4e-14	76.6
tr:K2ASB3_9BACT	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EKD52629.1}; EC=1.5.1.5 {ECO:0000313|EMBL:EKD52629.1};	29.71	239	131	8	49	284	43	247	4e-14	79.3
tr:A0A074Y1N1_AURPU	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:KEQ80821.1};	26.13	333	185	11	1	294	1	311	4e-14	81.6
tr:W1XRD7_9ZZZZ	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:ETJ32696.1}; Flags: Fragment;	42.39	92	47	2	179	270	3	88	5e-14	75.9
rs:WP_040201792	hypothetical protein [Geoalkalibacter subterraneus].	25.09	279	153	9	39	286	32	285	5e-14	80.1
rs:XP_009227521	methylenetetrahydrofolate dehydrogenase [Gaeumannomyces graminis var. tritici R3-111a-1].	24.41	340	182	12	2	293	9	321	5e-14	80.5
tr:I3M1Q9_SPETR	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSTOP00000002801};	39.00	100	61	0	3	102	51	150	5e-14	77.4
tr:N1Q2L9_DOTSN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EME48719.1};	26.53	294	156	11	31	286	31	302	5e-14	80.1
tr:G9P945_HYPAI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHK41072.1};	25.08	323	181	10	2	284	9	310	6e-14	80.5
tr:X1AQ60_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_L04334 {ECO:0000313|EMBL:GAG84900.1}; Flags: Fragment;	50.67	75	27	1	227	291	1	75	6e-14	75.5
tr:A0A074VME3_9PEZI	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:KEQ61895.1};	25.47	322	180	10	11	294	12	311	6e-14	81.3
tr:G9W1K1_SALET	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EHJ83865.1};	48.19	83	37	2	189	271	9	85	6e-14	76.3
rs:XP_001465553	methylenetetrahydrofolate dehydrogenase-like protein [Leishmania infantum JPCM5].	34.04	141	77	3	161	288	295	432	6e-14	81.3
rs:XP_001465553	methylenetetrahydrofolate dehydrogenase-like protein [Leishmania infantum JPCM5].	38.35	133	78	1	2	134	31	159	1e-08	65.5
rs:WP_020736803	hypothetical protein [Sorangium cellulosum].	25.00	324	183	11	2	292	14	310	7e-14	79.7
rs:NP_001136627	uncharacterized protein LOC100216752 [Zea mays].	44.55	101	56	0	2	102	94	194	8e-14	78.2
rs:WP_046833807	methenyltetrahydrofolate cyclohydrolase, partial [Xanthomonas axonopodis].	42.20	109	63	0	4	112	13	121	8e-14	76.3
rs:XP_003679590	hypothetical protein TDEL_0B02500 [Torulaspora delbrueckii].	24.53	318	177	12	10	286	18	313	9e-14	79.7
tr:S2K9Z8_MUCC1	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NAD+) {ECO:0000313|EMBL:EPB89125.1};	24.84	322	180	12	1	286	1	296	9e-14	79.3
tr:A0A0B4I5M5_9HYPO	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP(+)) {ECO:0000313|EMBL:KIE03424.1}; Flags: Fragment;	26.53	294	179	12	19	294	11	285	1e-13	79.0
rs:WP_033812208	hypothetical protein, partial [Escherichia coli].	48.28	87	45	0	1	87	1	87	1e-13	75.1
tr:W1UY83_9FIRM	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:ETI96608.1}; Flags: Fragment;	31.20	125	86	0	28	152	11	135	1e-13	76.3
tr:A0A060T148_BLAAD	SubName: Full=ARAD1C17600p {ECO:0000313|EMBL:CDP34658.1};	25.43	291	159	10	32	286	32	300	1e-13	79.3
rs:WP_043726778	hypothetical protein [Nocardia asiatica].	48.68	76	33	1	215	290	13	82	1e-13	75.1
tr:A0A0B2WR01_9HYPO	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:KHN96438.1};	25.85	294	193	8	1	291	1	272	1e-13	79.0
tr:S6TI99_PSESF	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EPN41611.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EPN41611.1}; Flags: Fragment;	56.06	66	23	1	225	290	1	60	1e-13	74.3
rs:XP_008390521	PREDICTED: bifunctional protein FolD 2-like [Malus domestica].	40.20	102	57	1	155	256	6	103	1e-13	75.1
tr:F0J9P7_AMBVA	SubName: Full=C1-tetrahydrofolate synthase {ECO:0000313|EMBL:DAA34537.1}; Flags: Fragment;	35.34	133	83	2	3	132	11	143	1e-13	76.3
tr:A0A0D8X7R5_DICVI	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein {ECO:0000313|EMBL:KJH40588.1};	38.93	131	68	3	1	128	1	122	1e-13	75.5
rs:WP_006709952	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Serratia symbiotica].	45.88	85	46	0	1	85	1	85	1e-13	74.7
tr:G5QW57_SALSE	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EHC93177.1};	50.67	75	31	2	189	263	9	77	2e-13	74.3
rs:WP_026852572	hypothetical protein [Geothrix fermentans].	23.59	301	187	11	6	289	9	283	2e-13	78.2
rs:XP_004029507	PREDICTED: bifunctional protein FolD-like [Gorilla gorilla gorilla].	44.94	89	49	0	73	161	5	93	2e-13	77.0
tr:G1M6Z1_AILME	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAMEP00000015111};	35.58	104	67	0	11	114	1	104	2e-13	74.7
tr:A0A0D2K068_9CHLO	SubName: Full=Strain SAG 48.87 unplaced genomic scaffold scaffold00508, whole genome shotgun sequence {ECO:0000313|EMBL:KIZ04093.1}; EC=3.5.4.9 {ECO:0000313|EMBL:KIZ04093.1};	42.53	87	45	2	113	197	5	88	2e-13	78.6
tr:A0A0D2K068_9CHLO	SubName: Full=Strain SAG 48.87 unplaced genomic scaffold scaffold00508, whole genome shotgun sequence {ECO:0000313|EMBL:KIZ04093.1}; EC=3.5.4.9 {ECO:0000313|EMBL:KIZ04093.1};	60.00	45	18	0	248	292	265	309	1e-06	59.3
rs:WP_037623214	methylenetetrahydrofolate dehydrogenase, partial [Streptomyces aureus].	26.39	269	151	10	30	282	33	270	2e-13	78.6
rs:XP_003860772	methylenetetrahydrofolate dehydrogenase-like protein [Leishmania donovani].	34.04	141	77	3	161	288	295	432	2e-13	79.7
rs:XP_003860772	methylenetetrahydrofolate dehydrogenase-like protein [Leishmania donovani].	38.35	133	78	1	2	134	31	159	2e-08	65.1
tr:A5DA37_PICGU	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EDK36044.2};	24.91	293	158	11	34	286	34	304	2e-13	78.6
tr:X0SM03_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_L00335 {ECO:0000313|EMBL:GAF82044.1}; Flags: Fragment;	52.70	74	22	1	233	293	1	74	2e-13	73.9
rs:XP_001643489	hypothetical protein Kpol_489p12 [Vanderwaltozyma polyspora DSM 70294].	25.63	316	174	10	11	286	17	311	2e-13	78.6
rs:XP_006963123	predicted protein [Trichoderma reesei QM6a].	25.46	326	176	14	2	284	9	310	3e-13	78.6
rs:XP_007820558	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein [Metarhizium robertsii ARSEF 23].	24.56	281	187	8	19	290	11	275	3e-13	77.8
tr:D7C142_STRBB	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ADI07943.1};	28.40	243	147	8	46	286	3	220	3e-13	77.4
rs:XP_003038005	hypothetical protein SCHCODRAFT_12752 [Schizophyllum commune H4-8].	26.03	315	161	11	20	284	20	312	3e-13	77.8
rs:XP_007812489	methenyltetrahydrofolate cyclohydrolase [Metarhizium acridum CQMa 102].	26.24	282	176	10	19	290	11	270	4e-13	77.4
gp:AK319160_1	AT2G38660 gene product [Arabidopsis thaliana]	39.80	98	59	0	5	102	65	162	4e-13	75.9
rs:WP_045714215	methenyltetrahydrofolate cyclohydrolase, partial [Salmonella enterica].	62.30	61	17	2	228	288	1	55	4e-13	73.2
rs:XP_002494869	ZYRO0A11594p [Zygosaccharomyces rouxii].	26.69	311	164	12	19	286	23	312	4e-13	77.8
rs:WP_033933632	methenyltetrahydrofolate cyclohydrolase, partial [Vibrio cholerae].	46.07	89	48	0	1	89	26	114	4e-13	74.3
rs:WP_037328582	methenyltetrahydrofolate cyclohydrolase [Anaerococcus lactolyticus].	25.37	272	177	7	15	283	9	257	4e-13	76.6
rs:XP_001486765	hypothetical protein PGUG_00142 [Meyerozyma guilliermondii ATCC 6260].	24.91	293	158	11	34	286	34	304	5e-13	77.8
tr:T1ABZ5_9ZZZZ	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase domain protein {ECO:0000313|EMBL:EQD58326.1}; EC=6.3.4.3 {ECO:0000313|EMBL:EQD58326.1}; Flags: Fragment;	63.79	58	21	0	78	135	1	58	5e-13	72.8
rs:XP_011530285	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X6 [Homo sapiens].	38.38	99	61	0	5	103	156	254	5e-13	76.6
tr:A0A0B4GDZ8_METAN	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP(+)) {ECO:0000313|EMBL:KID66469.1}; Flags: Fragment;	25.27	281	185	9	19	290	11	275	6e-13	77.0
rs:WP_041912711	hypothetical protein [Marinimicrobia bacterium JGI 0000059-E23].	40.40	99	58	1	1	99	1	98	6e-13	73.6
rs:XP_011530286	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X7 [Homo sapiens].	38.78	98	60	0	5	102	156	253	6e-13	76.3
tr:A0A0C9MVF5_9FUNG	SubName: Full=DNA, scaffold: scf_mam1_v10111, strain NBRC 6742, whole genome shotgun sequence {ECO:0000313|EMBL:GAN06088.1};	24.84	322	180	11	1	286	1	296	6e-13	77.0
rs:XP_011530284	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X5 [Homo sapiens].	38.78	98	60	0	5	102	156	253	6e-13	76.3
tr:M1VZ93_CLAP2	SubName: Full=Probable methylenetetrahydrofolate dehydrogenase (NAD+) {ECO:0000313|EMBL:CCE34737.1};	25.08	323	181	10	2	284	10	311	6e-13	77.4
tr:K0TNC7_THAOC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJK73402.1};	25.62	324	180	13	3	286	53	355	7e-13	78.2
rs:WP_021695563	methylenetetrahydrofolate dehydrogenase [Loktanella cinnabarina].	62.71	59	21	1	231	288	1	59	7e-13	72.8
tr:H9W3N6_PINTA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AFG56629.1}; Flags: Fragment;	45.07	71	37	1	100	168	1	71	7e-13	72.4
tr:A0A0D9Q3E2_METAN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KJK92992.1};	25.27	281	185	9	19	290	11	275	8e-13	76.6
rs:WP_039262134	hypothetical protein [Clostridium tetani].	28.29	258	144	11	29	286	17	233	8e-13	75.5
rs:XP_004178234	hypothetical protein TBLA_0A09280 [Tetrapisispora blattae CBS 6284].	25.08	327	182	12	10	294	18	323	9e-13	77.0
rs:WP_030821094	MULTISPECIES: methylenetetrahydrofolate dehydrogenase, partial [Streptomyces].	25.71	280	169	9	8	286	29	270	9e-13	76.3
rs:XP_003645945	hypothetical protein Ecym_4047 [Eremothecium cymbalariae DBVPG#7215].	25.60	332	179	13	1	286	1	310	9e-13	77.0
rs:WP_004828845	methenyltetrahydrofolate cyclohydrolase [Anaerococcus lactolyticus].	25.37	272	177	7	15	283	9	257	9e-13	75.9
tr:A0A075I788_9ARCH	SubName: Full=Methylenetetrahydrofolate dehydrogenase (FolD) {ECO:0000313|EMBL:AIF22562.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AIF22562.1};	72.73	44	12	0	249	292	13	56	9e-13	72.0
rs:WP_030112837	MULTISPECIES: methylenetetrahydrofolate dehydrogenase, partial [Streptomyces].	25.71	280	169	9	8	286	29	270	1e-12	76.3
tr:G5LZY9_SALET	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EHC40346.1}; EC=1.5.1.5 {ECO:0000313|EMBL:EHC40346.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EHC40346.1};	53.62	69	26	2	189	257	9	71	1e-12	73.2
tr:A0A084FY34_9PEZI	SubName: Full=Methylenetetrahydrofolate dehydrogenase [NAD(+)] {ECO:0000313|EMBL:KEZ39996.1}; EC=1.5.1.15 {ECO:0000313|EMBL:KEZ39996.1};	24.46	327	182	11	2	286	9	312	1e-12	76.6
tr:N1QNC3_SPHMS	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EMF17648.1};	23.83	298	165	11	32	290	35	309	1e-12	76.6
rs:WP_031057366	methylenetetrahydrofolate dehydrogenase, partial [Streptomyces sp. NRRL F-5702].	25.71	280	169	9	8	286	29	270	1e-12	75.9
tr:R9XGG2_ASHAC	SubName: Full=AaceriADR214Wp {ECO:0000313|EMBL:AGO12688.1};	26.01	296	156	12	32	286	36	309	1e-12	76.3
rs:WP_033989005	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas aeruginosa].	55.36	56	25	0	186	241	8	63	1e-12	71.6
rs:WP_039328203	hypothetical protein, partial [Candidatus Saccharibacteria oral taxon TM7x].	36.00	150	83	5	142	291	1	137	1e-12	73.2
tr:X1GQG0_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S07548 {ECO:0000313|EMBL:GAH59432.1}; Flags: Fragment;	36.29	124	78	1	6	128	14	137	1e-12	73.6
rs:WP_022095278	bifunctional protein FolD [Clostridium sp. CAG:568].	29.67	209	123	8	87	286	68	261	2e-12	75.5
tr:A0A075FY49_9ARCH	SubName: Full=Methylenetetrahydrofolate dehydrogenase (FolD) {ECO:0000313|EMBL:AIE94527.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AIE94527.1};	53.62	69	25	1	224	292	1	62	2e-12	71.2
tr:K7P3B3_PINMU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AFB34374.1}; Flags: Fragment;	43.66	71	38	1	100	168	1	71	2e-12	71.2
tr:A0A074WE14_9PEZI	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:KEQ68122.1};	25.08	315	176	10	18	294	19	311	2e-12	77.0
tr:F6Q8T4_MACMU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000020401};	38.04	92	57	0	11	102	1	92	2e-12	72.0
rs:WP_030198262	methylenetetrahydrofolate dehydrogenase, partial [Streptomyces puniceus].	25.36	280	170	9	8	286	29	270	2e-12	75.1
tr:K7P314_PINCE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AFB34373.1}; Flags: Fragment;	43.66	71	38	1	100	168	1	71	2e-12	71.2
gp:CP007423_323	hypothetical protein [Salmonella enterica subsp. enterica serovar Enteritidis str.]	48.00	75	39	0	1	75	1	75	2e-12	71.2
rs:XP_006682775	hypothetical protein BATDEDRAFT_18106 [Batrachochytrium dendrobatidis JAM81].	21.74	322	191	9	1	286	1	297	2e-12	75.5
tr:A0A074YAL1_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KEQ94833.1};	25.08	315	176	10	18	294	19	311	3e-12	75.9
rs:WP_019117556	hypothetical protein [Anaerococcus obesiensis].	23.77	265	179	7	17	277	7	252	4e-12	74.3
tr:Q8IY64_HUMAN	SubName: Full=MTHFD2L protein {ECO:0000313|EMBL:AAH37529.2}; SubName: Full=Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 {ECO:0000313|Ensembl:ENSP00000387614};	38.04	92	57	0	11	102	1	92	4e-12	71.2
rs:XP_007777336	methylenetetrahydrofolate dehydrogenase (NAD+) [Coniosporium apollinis CBS 100218].	25.24	309	166	12	18	286	22	305	4e-12	75.1
rs:XP_006667518	methylenetetrahydrofolate dehydrogenase [Cordyceps militaris CM01].	26.18	317	169	14	12	284	15	310	4e-12	75.1
tr:K7P4B6_LARDC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AFB34371.1}; Flags: Fragment;	42.25	71	39	1	100	168	1	71	4e-12	70.5
tr:K1UD81_9ZZZZ	SubName: Full=Protein containing Tetrahydrofolate dehydrogenase/cyclohydrolase domain protein {ECO:0000313|EMBL:EKC77954.1}; EC=6.3.4.3 {ECO:0000313|EMBL:EKC77954.1}; Flags: Fragment;	71.11	45	13	0	250	294	1	45	4e-12	69.7
tr:A0A0C9M2Z7_9FUNG	SubName: Full=Fungal sp. No.11243 DNA, scaffold: sccafold0017, whole genome shotgun sequence {ECO:0000313|EMBL:GAM91441.1};	22.93	314	182	10	11	286	16	307	5e-12	74.7
tr:S8C2P3_9LAMI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPS58711.1}; Flags: Fragment;	63.27	49	18	0	241	289	1	49	5e-12	69.7
tr:X0WAI1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S16969 {ECO:0000313|EMBL:GAG21583.1}; Flags: Fragment;	47.56	82	36	1	207	288	3	77	6e-12	70.5
rs:XP_012059378	PREDICTED: LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Atta cephalotes].	62.50	56	21	0	237	292	1	56	6e-12	75.9
rs:XP_008720887	hypothetical protein HMPREF1541_08346 [Cyphellophora europaea CBS 101466].	23.93	305	173	10	19	286	21	303	7e-12	74.3
tr:D8M4P0_BLAHO	RecName: Full=Superoxide dismutase {ECO:0000256|RuleBase:RU000414}; EC=1.15.1.1 {ECO:0000256|RuleBase:RU000414};	42.00	100	56	1	189	288	2	99	7e-12	75.5
rs:WP_003818739	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Bifidobacterium bifidum].	38.38	99	57	1	78	172	3	101	7e-12	70.5
rs:XP_007603349	tetrahydrofolate dehydrogenase/cyclohydrolase [Colletotrichum fioriniae PJ7].	24.62	325	180	12	2	284	10	311	7e-12	74.7
tr:A0A078J371_BRANA	SubName: Full=BnaCnng31000D protein {ECO:0000313|EMBL:CDY56692.1};	52.46	61	29	0	232	292	18	78	7e-12	70.1
tr:A0A086TFG8_ACRCH	SubName: Full=Methylenetetrahydrofolate dehydrogenase [NAD(+)]-like protein {ECO:0000313|EMBL:KFH48100.1};	23.84	323	185	10	2	284	9	310	8e-12	74.3
tr:X1A603_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_L07694 {ECO:0000313|EMBL:GAG77169.1}; Flags: Fragment;	64.91	57	13	1	234	290	1	50	8e-12	69.3
rs:WP_032760355	MULTISPECIES: methylenetetrahydrofolate dehydrogenase, partial [Streptomyces].	25.00	280	171	9	8	286	29	270	9e-12	73.6
tr:K7GJF6_PELSI	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPSIP00000020417}; Flags: Fragment;	25.86	232	159	5	59	287	71	292	9e-12	75.5
rs:WP_004838957	hypothetical protein [Anaerococcus vaginalis].	23.19	263	183	5	17	277	7	252	9e-12	73.2
rs:WP_022107331	bifunctional protein FolD [Clostridium sp. CAG:138].	54.29	70	25	2	224	293	1	63	1e-11	69.3
tr:A0A0B7ND42_9FUNG	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CEP13332.1};	27.01	311	165	15	11	286	12	295	1e-11	73.6
tr:S9VZM3_SCHCR	SubName: Full=Methylenetetrahydrofolate reductase {ECO:0000313|EMBL:EPY53103.1};	23.42	333	193	14	2	297	12	319	1e-11	73.9
tr:W1NQM8_AMBTC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERM97119.1};	37.50	104	65	0	2	105	13	116	1e-11	70.5
tr:D7FWG9_ECTSI	SubName: Full=Putative methylene tetrahydrofolate dehydrogenase {ECO:0000313|EMBL:CBJ32057.1};	26.02	319	173	14	6	286	15	308	1e-11	73.9
tr:A0A009RKK4_ACIBA	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein {ECO:0000313|EMBL:EXC41676.1}; Flags: Fragment;	35.40	113	71	2	3	114	2	113	1e-11	70.1
rs:WP_039940396	methenyltetrahydrofolate cyclohydrolase, partial [Streptomyces himastatinicus].	48.72	78	32	3	215	292	1	70	1e-11	68.9
rs:XP_003297255	hypothetical protein PTT_07593 [Pyrenophora teres f. teres 0-1].	24.52	310	175	10	21	293	22	309	1e-11	73.6
rs:WP_030740831	methylenetetrahydrofolate dehydrogenase, partial [Streptomyces griseus].	25.00	280	171	9	8	286	29	270	1e-11	72.8
rs:WP_042818577	methylenetetrahydrofolate dehydrogenase, partial [Streptomyces sp. RSD-27].	26.75	243	151	10	46	286	5	222	1e-11	73.2
rs:XP_002420089	NAD-dependent methylenetetrahydrofolate dehydrogenase, putative [Candida dubliniensis CD36].	22.78	316	182	11	11	286	10	303	1e-11	73.6
rs:WP_044566108	methenyltetrahydrofolate cyclohydrolase [Anaerococcus sp. 9402080].	22.22	270	194	5	14	283	4	257	1e-11	72.8
rs:WP_032069367	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Acinetobacter baumannii].	35.14	111	70	2	5	114	2	111	2e-11	69.7
gpu:CP011497_485	hypothetical protein [Streptomyces incarnatus]	51.43	70	24	1	224	293	1	60	2e-11	68.6
rs:WP_004612971	hypothetical protein [Clostridium nexile CAG:348].	46.34	82	38	1	207	288	9	84	2e-11	69.3
tr:U4L9G2_PYROM	SubName: Full=Similar to Methylenetetrahydrofolate dehydrogenase [NAD(+)] acc. no. Q9P786 {ECO:0000313|EMBL:CCX10206.1};	22.68	291	167	10	32	286	49	317	2e-11	73.2
rs:XP_003794507	PREDICTED: LOW QUALITY PROTEIN: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Otolemur garnettii].	39.25	107	57	3	186	290	93	193	2e-11	71.2
rs:WP_046686551	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Mycobacterium arupense].	36.78	87	55	0	19	105	2	88	2e-11	69.3
tr:G7XQY4_ASPKW	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:GAA89257.1};	23.33	330	187	11	2	292	11	313	2e-11	73.2
tr:A0A0B7JWR9_BIOOC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CEO46921.1}; Flags: Fragment;	23.84	323	185	10	2	284	9	310	2e-11	73.2
tr:E7Q6D5_YEASB	SubName: Full=Mtd1p {ECO:0000313|EMBL:EGA57837.1};	25.00	284	166	12	10	250	12	291	2e-11	72.4
rs:XP_003713430	methylenetetrahydrofolate dehydrogenase [Magnaporthe oryzae 70-15].	25.08	319	165	12	12	284	16	306	2e-11	72.8
rs:NP_984310	ADR214Wp [Ashbya gossypii ATCC 10895].	25.90	305	163	12	23	286	27	309	3e-11	72.8
tr:A0A066XB42_COLSU	SubName: Full=Putative tetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:KDN66408.1};	24.15	323	184	11	2	284	10	311	3e-11	72.8
tr:F0XRQ2_GROCL	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EFW99587.1};	26.67	300	157	12	27	284	35	313	3e-11	72.8
tr:G8B9E8_CANPC	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CCE41248.1};	22.40	317	182	12	11	286	10	303	3e-11	72.8
tr:D3BFI3_POLPA	SubName: Full=Methylenetetrahydrofolate dehydrogenase NAD {ECO:0000313|EMBL:EFA79897.1};	24.13	315	178	11	6	286	15	302	3e-11	72.8
rs:WP_039887399	hypothetical protein [Microcoleus vaginatus].	53.62	69	29	2	218	286	5	70	3e-11	68.2
rs:WP_047201544	methenyltetrahydrofolate cyclohydrolase, partial [Shigella flexneri].	62.07	58	16	2	232	289	1	52	3e-11	67.8
rs:WP_031985243	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Acinetobacter baumannii].	37.50	104	63	2	3	105	2	104	3e-11	68.9
rs:WP_031727952	methenyltetrahydrofolate cyclohydrolase, partial [Mycobacterium tuberculosis].	37.96	108	66	1	1	108	1	107	3e-11	68.9
rs:WP_021277285	tetrahydrofolate dehydrogenase [Bacteriovorax sp. DB6_IX].	23.93	305	186	10	6	290	4	282	4e-11	72.0
tr:A0A0A6ZMQ2_SHIDY	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) {ECO:0000313|EMBL:AHA63170.1}; EC=1.5.1.5 {ECO:0000313|EMBL:AHA63170.1}; EC=3.5.4.9 {ECO:0000313|EMBL:AHA63170.1};	56.72	67	23	2	231	297	1	61	4e-11	67.4
rs:WP_031985401	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Acinetobacter baumannii].	37.25	102	62	2	5	105	2	102	4e-11	68.6
tr:A0A0D2IDI0_9EURO	SubName: Full=Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.7, whole genome shotgun sequence {ECO:0000313|EMBL:KIX01291.1};	23.51	302	172	10	22	286	27	306	4e-11	72.4
rs:XP_008092896	tetrahydrofolate dehydrogenase/cyclohydrolase [Colletotrichum graminicola M1.001].	25.62	320	169	12	11	284	15	311	5e-11	72.4
rs:XP_007689213	hypothetical protein COCMIDRAFT_6403 [Bipolaris oryzae ATCC 44560].	23.28	335	183	12	2	293	7	310	5e-11	72.0
rs:XP_001938409	bifunctional protein folD [Pyrenophora tritici-repentis Pt-1C-BFP].	24.42	303	170	10	21	286	22	302	5e-11	72.0
rs:WP_029980392	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Prochlorococcus sp. scB245a_521K15].	38.89	90	55	0	6	95	5	94	5e-11	67.8
rs:WP_029979075	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Prochlorococcus sp. scB243_498P3].	39.33	89	54	0	6	94	5	93	5e-11	67.8
tr:H1VCR0_COLHI	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:CCF38013.1};	25.62	320	169	12	11	284	15	311	6e-11	72.0
tr:B6WAQ3_9FIRM	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EEB35585.1};	26.90	171	110	5	118	286	4	161	6e-11	69.3
rs:XP_001386040	hypothetical protein PICST_73792 [Scheffersomyces stipitis CBS 6054].	23.53	306	172	11	21	286	27	310	6e-11	71.6
tr:D8M4P1_BLAHO	SubName: Full=Singapore isolate B (sub-type 7) whole genome shotgun sequence assembly, scaffold_22 {ECO:0000313|EMBL:CBK23030.2};	34.38	96	63	0	36	131	5	100	6e-11	68.2
rs:XP_007581390	putative methylenetetrahydrofolate dehydrogenase protein [Neofusicoccum parvum UCRNP2].	25.83	302	167	11	22	286	22	303	7e-11	71.6
rs:XP_003870168	Mtd1 protein [Candida orthopsilosis Co 90-125].	21.75	308	177	11	20	286	19	303	7e-11	71.6
tr:W4VT13_ATTCE	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:ACEP10093-PB};	63.46	52	19	0	241	292	76	127	7e-11	72.4
rs:WP_005572855	methylenetetrahydrofolate dehydrogenase, partial [Rhodococcus wratislaviensis].	45.45	77	36	1	215	291	2	72	8e-11	67.4
tr:X1RVK3_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_L05189 {ECO:0000313|EMBL:GAI84713.1}; Flags: Fragment;	37.63	93	58	0	4	96	49	141	8e-11	68.6
tr:A0A0C7BK70_9FUNG	SubName: Full=RMATCC62417_07168 protein {ECO:0000313|EMBL:CEG71436.1};	23.60	322	184	11	1	286	1	296	8e-11	71.2
rs:WP_029980863	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Prochlorococcus sp. scB245a_518D8].	54.41	68	28	2	225	291	3	68	8e-11	67.0
tr:A0A0A1NBY3_9FUNG	SubName: Full=Putative Methylenetetrahydrofolate reductase {ECO:0000313|EMBL:CEI90131.1};	23.60	322	184	11	1	286	1	296	8e-11	71.2
tr:A0A0D6LYC8_9BILA	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EPB75116.1};	40.91	110	56	3	119	223	2	107	9e-11	68.2
rs:XP_007917427	putative methylenetetrahydrofolate dehydrogenase protein [Togninia minima UCRPA7].	24.50	302	157	11	28	284	32	307	9e-11	71.2
tr:M1BHY9_SOLTU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:PGSC0003DMT400045636};	39.05	105	63	1	2	105	25	129	9e-11	68.6
rs:XP_001104996	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Macaca mulatta].	45.31	64	35	0	3	66	37	100	1e-10	68.2
rs:XP_001104996	PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like [Macaca mulatta].	81.82	33	6	0	259	291	97	129	3e-08	61.6
tr:A0A0A1NEX6_9FUNG	SubName: Full=Putative Methylenetetrahydrofolate reductase {ECO:0000313|EMBL:CEI95385.1};	23.60	322	184	11	1	286	1	296	1e-10	70.9
rs:XP_002625325	methylenetetrahydrofolate dehydrogenase [Blastomyces dermatitidis SLH14081].	22.77	303	174	10	22	286	28	308	1e-10	71.2
rs:WP_002300057	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Streptococcus mutans].	40.66	91	54	0	4	94	3	93	1e-10	67.0
tr:A0A0D2CBM7_9EURO	SubName: Full=Strain CBS 89968 unplaced genomic scaffold supercont1.1, whole genome shotgun sequence {ECO:0000313|EMBL:KIW20919.1};	25.00	296	163	12	28	286	30	303	1e-10	70.9
rs:XP_003883191	GI23694, related [Neospora caninum Liverpool].	37.50	104	60	2	141	244	346	444	1e-10	71.6
rs:WP_007442299	NAD(P)-binding domain protein, partial [Streptomyces coelicoflavus].	52.17	69	33	0	34	102	39	107	1e-10	67.4
tr:A0A0A6JPU6_CANAX	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NAD+) {ECO:0000313|EMBL:KHC50998.1};	26.29	194	120	5	11	185	10	199	1e-10	70.9
rs:WP_028245182	hypothetical protein [Pseudoclavibacter soli].	25.48	314	170	13	1	278	5	290	1e-10	70.5
tr:A0A099U5G7_9HELI	SubName: Full=5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:KGL16147.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KGL16147.1}; EC=3.5.4.9 {ECO:0000313|EMBL:KGL16147.1}; Flags: Fragment;	55.17	58	20	1	233	290	1	52	1e-10	65.9
tr:A0A0C4DRL1_MAGP6	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblFungi:MAPG_02524T0};	23.71	329	178	11	2	284	9	310	1e-10	70.5
tr:N4V0A6_COLOR	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:ENH76987.1};	25.00	324	173	12	3	284	14	309	1e-10	70.9
gp:AX884389_1	Sequence 252 from Patent EP1033401. [Homo sapiens]	37.86	103	64	0	3	105	37	139	2e-10	67.8
rs:WP_000321548	hypothetical protein, partial [Leptospira interrogans].	38.27	81	40	1	215	295	2	72	2e-10	66.2
rs:WP_041877691	methenyltetrahydrofolate cyclohydrolase, partial [Verrucomicrobia bacterium SCGC AAA164-O14].	42.67	75	43	0	60	134	2	76	2e-10	66.2
sp:MTD1_DICDI	RecName: Full=Methylenetetrahydrofolate dehydrogenase [NAD(+)]; EC=1.5.1.15;	22.64	318	180	10	6	286	15	303	2e-10	70.1
tr:A0A0A6KZ41_CANAX	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NAD+) {ECO:0000313|EMBL:KHC37445.1};	26.29	194	120	5	11	185	10	199	2e-10	70.5
rs:XP_717291	hypothetical protein CaO19.11291 [Candida albicans SC5314].	26.29	194	120	5	11	185	10	199	2e-10	70.5
rs:WP_003351136	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Pseudomonas syringae].	67.39	46	15	0	249	294	4	49	2e-10	65.9
tr:X1E056_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S26394 {ECO:0000313|EMBL:GAH26651.1}; Flags: Fragment;	48.39	62	32	0	171	232	1	62	2e-10	65.5
tr:A0A059AF53_EUCGR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KCW52291.1};	35.85	106	68	0	2	107	67	172	2e-10	68.2
tr:A0A0B2X482_9HYPO	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:KHO00116.1};	24.15	323	184	12	2	284	9	310	2e-10	70.5
tr:W9I3Z6_FUSOX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EWY87689.1};	23.21	293	192	8	14	290	21	296	2e-10	70.1
rs:WP_004045989	hypothetical protein, partial [Lactobacillus sp. ASF360].	36.73	98	61	1	3	100	2	98	2e-10	66.2
tr:C5GTZ9_AJEDR	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EEQ84702.1};	22.01	318	184	11	22	297	28	323	2e-10	70.5
rs:WP_041638520	hypothetical protein [Marinitoga piezophila].	23.68	304	172	10	29	293	31	313	2e-10	70.1
tr:A0A094HX32_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFZ19382.1};	24.53	322	181	12	2	286	9	305	2e-10	70.1
tr:A0A0A1TQI8_9HYPO	SubName: Full=Putative Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:CEJ94008.1};	24.00	325	182	13	2	284	12	313	3e-10	70.1
tr:A0A0D2DHI3_9EURO	SubName: Full=Strain CBS 72588 unplaced genomic scaffold supercont1.5, whole genome shotgun sequence {ECO:0000313|EMBL:KIW41875.1};	23.99	296	166	11	28	286	30	303	3e-10	70.1
tr:H2J817_MARPK	SubName: Full=5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:AEX85508.1};	23.68	304	172	10	29	293	32	314	3e-10	70.1
rs:XP_007827929	Methylenetetrahydrofolate dehydrogenase [Pestalotiopsis fici W106-1].	24.71	340	185	15	2	295	9	323	3e-10	70.1
tr:A0A0D1Y3P5_9EURO	SubName: Full=Exophiala sideris strain CBS 121828 unplaced genomic scaffold supercont1.4, whole genome shotgun sequence {ECO:0000313|EMBL:KIV77437.1};	23.59	301	161	12	28	286	30	303	3e-10	70.1
tr:X1URB4_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_S01844 {ECO:0000313|EMBL:GAJ02426.1}; Flags: Fragment;	46.97	66	35	0	5	70	4	69	3e-10	66.6
tr:A0A010J0Y1_ACIBA	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EXE62785.1};	38.64	88	47	1	206	293	12	92	3e-10	65.9
tr:X0MF37_FUSOX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EXM19205.1};	23.21	293	192	8	14	290	21	296	3e-10	69.7
rs:WP_032049081	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Acinetobacter baumannii].	38.64	88	47	1	206	293	13	93	3e-10	65.9
rs:XP_002153027	methylenetetrahydrofolate dehydrogenase [Talaromyces marneffei ATCC 18224].	22.36	322	182	10	11	286	12	311	3e-10	69.7
tr:M5CAM3_THACB	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase {ECO:0000313|EMBL:CCO32882.1}; EC=6.3.4.3 {ECO:0000313|EMBL:CCO32882.1};	34.13	126	77	2	3	122	29	154	3e-10	67.0
tr:A0A017S483_9EURO	SubName: Full=NAD(P)-binding protein {ECO:0000313|EMBL:EYE91843.1};	22.36	322	185	12	3	286	10	304	3e-10	69.7
rs:XP_002836726	hypothetical protein [Tuber melanosporum Mel28].	24.36	312	176	10	12	286	18	306	4e-10	69.7
tr:X1PI10_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S19462 {ECO:0000313|EMBL:GAI55937.1}; Flags: Fragment;	65.38	52	17	1	240	291	3	53	4e-10	64.7
rs:XP_003054353	predicted protein [Nectria haematococca mpVI 77-13-4].	24.62	333	188	13	2	292	9	320	4e-10	69.7
rs:XP_794654	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic [Strongylocentrotus purpuratus].	60.38	53	21	0	241	293	47	99	4e-10	70.5
rs:XP_008883224	tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain-containing protein [Hammondia hammondi].	33.04	115	72	2	141	255	510	619	4e-10	70.1
rs:XP_004197207	Piso0_004447 [Millerozyma farinosa CBS 7064].	25.61	289	148	12	34	280	41	304	4e-10	69.3
rs:WP_041661369	hypothetical protein, partial [Acaryochloris marina].	28.75	240	142	11	46	283	52	264	5e-10	68.6
tr:C1H1N5_PARBA	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EEH33772.2};	22.11	303	176	10	22	286	26	306	5e-10	69.3
tr:J5KEC3_PASMD	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EJS86134.1}; Flags: Fragment;	68.89	45	14	0	249	293	2	46	5e-10	64.3
rs:XP_002372781	methylenetetrahydrofolate dehydrogenase [Aspergillus flavus NRRL3357].	22.29	323	187	11	2	286	11	307	5e-10	69.3
tr:H1DB98_9FUSO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHO17895.1};	50.00	56	28	0	97	152	1	56	5e-10	65.1
tr:A8ZN24_ACAM1	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ABW32223.1};	28.75	240	142	11	46	283	52	264	6e-10	69.7
tr:A0A094ADA6_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY27636.1};	24.22	322	182	12	2	286	9	305	6e-10	68.9
tr:S0E7M5_GIBF5	SubName: Full=Related to MIS1-C1-tetrahydrofolate synthase, mitochondrial {ECO:0000313|EMBL:CCT70655.1};	24.32	292	189	10	14	290	21	295	6e-10	68.9
tr:S9Q6U8_SCHOY	SubName: Full=Methylenetetrahydrofolate reductase {ECO:0000313|EMBL:EPX75368.1};	22.22	333	197	14	2	297	12	319	6e-10	68.9
tr:A0A0D0BJ99_9HOMO	SubName: Full=Unplaced genomic scaffold CY34scaffold_34, whole genome shotgun sequence {ECO:0000313|EMBL:KIK45982.1};	24.28	346	168	11	15	284	17	344	6e-10	69.3
tr:V5G013_BYSSN	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:GAD94217.1};	23.13	294	164	10	32	286	37	307	6e-10	68.9
rs:XP_002549630	methylenetetrahydrofolate dehydrogenase [Candida tropicalis MYA-3404].	24.23	194	124	5	11	185	10	199	7e-10	68.9
tr:W1XDG2_9ZZZZ	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:ETJ28171.1}; Flags: Fragment;	51.56	64	24	1	220	283	1	57	7e-10	64.3
tr:F6ZW66_MACMU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000012744};	36.08	97	58	2	3	96	37	132	7e-10	67.0
tr:F6ZW66_MACMU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000012744};	75.00	36	9	0	256	291	167	202	3e-08	62.4
tr:B0FDC6_DROSL	SubName: Full=Pugilist {ECO:0000313|EMBL:ABY55759.1}; Flags: Fragment;	61.54	52	20	0	241	292	1	52	7e-10	67.4
rs:XP_007679599	hypothetical protein BAUCODRAFT_240855 [Baudoinia compniacensis UAMH 10762].	20.87	321	190	12	2	284	19	313	8e-10	68.6
tr:A0A094BH72_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY34655.1};	23.91	322	183	12	2	286	9	305	8e-10	68.6
tr:W9MBS9_FUSOX	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NAD+) {ECO:0000313|EMBL:EWZ91370.1};	23.72	333	191	13	2	292	9	320	8e-10	68.6
tr:A0A090QYT5_9GAMM	SubName: Full=Methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:GAL07438.1}; EC=1.5.1.5 {ECO:0000313|EMBL:GAL07438.1}; EC=3.5.4.9 {ECO:0000313|EMBL:GAL07438.1};	55.17	58	20	1	234	291	1	52	9e-10	63.5
tr:W4Z1I8_STRPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:SPU_021979-tr};	62.00	50	19	0	244	293	20	69	9e-10	69.3
tr:W9MBD7_FUSOX	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NAD+) {ECO:0000313|EMBL:EWZ91369.1};	23.72	333	191	13	2	292	25	336	9e-10	68.6
tr:A0A063BTY6_9HYPO	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:KDB12318.1};	23.84	323	185	13	2	284	9	310	1e-09	68.6
tr:A0A0B7N7Z9_9FUNG	RecName: Full=Tubulin gamma chain {ECO:0000256|RuleBase:RU003506};	22.98	322	186	10	1	286	1	296	1e-09	68.9
tr:A0A094EDJ9_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY74513.1};	24.22	322	182	12	2	286	9	305	1e-09	68.2
tr:X0M2L1_FUSOX	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NAD+) {ECO:0000313|EMBL:EXM27752.1};	23.72	333	191	13	2	292	9	320	1e-09	68.2
tr:X0M301_FUSOX	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NAD+) {ECO:0000313|EMBL:EXM27751.1};	23.72	333	191	13	2	292	25	336	1e-09	68.6
tr:F3GEE1_PSESJ	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EGH45441.1}; EC=1.5.1.5 {ECO:0000313|EMBL:EGH45441.1}; Flags: Fragment;	65.22	46	16	0	249	294	4	49	1e-09	63.5
tr:F9F403_FUSOF	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGU88329.1};	23.72	333	191	13	2	292	55	366	1e-09	68.6
tr:X0KD59_FUSOX	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NAD+) {ECO:0000313|EMBL:EXM11539.1};	23.72	333	191	13	2	292	9	320	1e-09	68.2
tr:X0KDG8_FUSOX	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NAD+) {ECO:0000313|EMBL:EXM11538.1};	23.72	333	191	13	2	292	25	336	1e-09	68.2
sp:MTD1_SCHPO	RecName: Full=Methylenetetrahydrofolate dehydrogenase [NAD(+)]; EC=1.5.1.15;	23.21	336	190	15	2	297	12	319	1e-09	67.8
tr:A0A0D2ET64_9EURO	SubName: Full=Strain CBS 118157 unplaced genomic scaffold supercont1.6, whole genome shotgun sequence {ECO:0000313|EMBL:KIW50994.1};	23.65	296	167	10	28	286	30	303	2e-09	67.8
rs:XP_009251475	hypothetical protein FPSE_00080 [Fusarium pseudograminearum CS3096].	23.72	333	191	13	2	292	9	320	2e-09	67.8
tr:K2BKT1_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKD62639.1}; Flags: Fragment;	47.37	76	26	2	215	290	1	62	2e-09	63.2
rs:XP_011316083	methylenetetrahydrofolate dehydrogenase [Fusarium graminearum PH-1].	23.72	333	191	13	2	292	9	320	2e-09	67.8
tr:A0A084QRF5_9HYPO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFA66540.1};	23.22	323	187	10	2	284	9	310	2e-09	67.8
tr:K2SA87_MACPH	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:EKG21807.1};	25.17	302	167	11	22	286	22	301	2e-09	67.4
tr:W9ZNR1_FUSOX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EXK33464.1};	22.87	293	193	9	14	290	21	296	2e-09	67.4
rs:WP_015778060	methenyltetrahydrofolate cyclohydrolase [Anaerococcus prevotii].	25.78	256	160	8	37	284	25	258	2e-09	66.6
tr:A0A0D2AML5_9PEZI	SubName: Full=Verruconis gallopava strain CBS 43764 unplaced genomic scaffold supercont1.4, whole genome shotgun sequence {ECO:0000313|EMBL:KIW07730.1};	25.00	296	161	12	29	286	36	308	2e-09	67.4
tr:A0A090MIA7_9HYPO	SubName: Full=WGS project CBMI000000000 data, contig CS3069_c001894 {ECO:0000313|EMBL:CEG04712.1};	23.28	335	190	11	2	292	9	320	2e-09	67.4
tr:A0A096PFB5_9HYPO	SubName: Full=WGS project CBMG000000000 data, contig CS5907-c001286 {ECO:0000313|EMBL:CEG03542.1};	23.72	333	191	13	2	292	9	320	2e-09	67.4
rs:XP_002288445	predicted protein [Thalassiosira pseudonana CCMP1335].	24.15	323	185	13	3	286	15	316	2e-09	67.8
rs:WP_004835064	methenyltetrahydrofolate cyclohydrolase [Anaerococcus prevotii].	24.40	250	170	6	37	283	25	258	2e-09	66.6
rs:XP_009159966	methylenetetrahydrofolate dehydrogenase (NAD+) [Exophiala dermatitidis NIH/UT8656].	22.95	292	166	11	32	286	33	302	2e-09	67.4
tr:G7E3J4_MIXOS	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GAA97404.1};	23.76	362	181	12	3	286	2	346	2e-09	67.4
tr:A0A084B4P6_STACH	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KEY72525.1};	23.22	323	187	10	2	284	9	310	2e-09	67.4
tr:A0A093HG78_GAVST	SubName: Full=C-1-tetrahydrofolate synthase, cytoplasmic {ECO:0000313|EMBL:KFV53628.1}; Flags: Fragment;	56.60	53	23	0	241	293	13	65	2e-09	67.8
rs:WP_033969399	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas aeruginosa].	57.41	54	17	1	237	290	1	48	2e-09	62.4
rs:WP_037213632	methenyltetrahydrofolate cyclohydrolase, partial [Rhodococcus sp. R04].	41.33	75	41	2	218	292	1	72	2e-09	63.2
rs:XP_007799831	Methylenetetrahydrofolate dehydrogenase [Endocarpon pusillum Z07020].	23.43	303	171	11	22	286	23	302	3e-09	67.0
tr:D3TL51_GLOMM	SubName: Full=C1-tetrahydrofolate synthase {ECO:0000313|EMBL:ADD18346.1}; Flags: Fragment;	65.31	49	17	0	241	289	1	49	3e-09	67.8
rs:XP_001876526	predicted protein [Laccaria bicolor S238N-H82].	23.05	321	184	12	5	284	9	307	3e-09	66.6
tr:X0KIH7_FUSOX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EXM08547.1};	22.87	293	193	9	14	290	21	296	3e-09	66.6
tr:W1QBS2_OGAPD	SubName: Full=Methylenetetrahydrofolate dehydrogenase [NAD(+)] {ECO:0000313|EMBL:ESW98501.1}; EC=1.5.1.15 {ECO:0000313|EMBL:ESW98501.1};	23.81	315	176	11	11	286	8	297	3e-09	66.6
rs:XP_010019202	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial-like, partial [Nestor notabilis].	27.85	237	143	7	59	293	59	269	3e-09	67.4
tr:X1V0J9_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_S13385 {ECO:0000313|EMBL:GAJ05686.1}; Flags: Fragment;	49.21	63	31	1	1	63	1	62	3e-09	62.4
rs:WP_038838752	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas aeruginosa].	64.29	42	15	0	249	290	6	47	3e-09	62.0
tr:A0A077WJN7_9FUNG	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CDS06827.1};	22.74	321	186	11	2	286	4	298	4e-09	66.6
tr:W9PPC5_FUSOX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EXA41605.1};	23.21	293	192	9	14	290	21	296	4e-09	66.2
tr:R4X856_TAPDE	SubName: Full=Methylenetetrahydrofolate dehydrogenase5 / FY16936 {ECO:0000313|EMBL:CCG81704.1};	23.27	318	182	14	4	284	6	298	4e-09	66.2
tr:U3ISQ0_ANAPL	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAPLP00000010273}; Flags: Fragment;	26.24	202	134	5	34	233	21	209	4e-09	67.4
rs:XP_007444522	PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic-like, partial [Python bivittatus].	56.86	51	22	0	241	291	8	58	4e-09	67.0
rs:XP_004350408	methylenetetrahydrofolate dehydrogenase [Dictyostelium fasciculatum].	22.86	315	182	10	6	286	15	302	5e-09	66.2
tr:A0A068SI93_9FUNG	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:CDH61051.1};	22.74	321	186	11	2	286	4	298	5e-09	66.2
rs:WP_003818165	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Bifidobacterium bifidum].	39.18	97	58	1	6	102	5	100	5e-09	62.8
rs:XP_008023440	hypothetical protein SETTUDRAFT_128447 [Setosphaeria turcica Et28A].	23.81	315	171	12	21	293	22	309	5e-09	66.2
tr:W2FSB1_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETK72950.1}; Flags: Fragment;	26.95	308	162	13	15	286	39	319	5e-09	66.2
tr:U9TJV9_RHIID	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESA06568.1}; Flags: Fragment;	26.99	289	151	13	34	286	5	269	6e-09	65.9
rs:XP_005008961	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial [Anas platyrhynchos].	26.24	202	134	5	34	233	45	233	6e-09	67.0
rs:XP_002487515	methylenetetrahydrofolate dehydrogenase [Talaromyces stipitatus ATCC 10500].	22.29	332	185	11	2	286	7	312	6e-09	66.2
tr:I1CD60_RHIO9	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EIE86390.1};	22.98	322	186	11	1	286	1	296	6e-09	65.9
rs:XP_008897899	hypothetical protein PPTG_05912 [Phytophthora parasitica INRA-310].	26.38	307	165	12	15	286	22	302	6e-09	65.9
tr:A0A094G2M4_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY97281.1};	23.91	322	183	12	2	286	9	305	6e-09	66.2
tr:A0A015KSQ0_9GLOM	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NAD(+)) {ECO:0000313|EMBL:EXX70634.1};	26.99	289	151	13	34	286	9	273	7e-09	65.5
tr:A0A094I285_9PEZI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY90642.1};	23.60	322	184	12	2	286	9	305	7e-09	65.9
rs:XP_003659599	hypothetical protein MYCTH_2296847 [Myceliophthora thermophila ATCC 42464].	23.84	323	185	13	2	284	9	310	7e-09	65.9
tr:A0A0C3NSY1_PHLGI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIP08334.1};	25.73	342	167	12	5	284	11	327	7e-09	65.9
rs:XP_005790661	tetrahydrofolate dehydrogenase/cyclohydrolase, partial [Emiliania huxleyi CCMP1516].	39.36	94	53	1	142	235	1	90	8e-09	62.0
rs:XP_003015423	hypothetical protein ARB_06549 [Arthroderma benhamiae CBS 112371].	21.64	305	180	10	22	289	27	309	8e-09	65.9
rs:XP_008939193	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Merops nubicus].	56.86	51	22	0	243	293	2	52	8e-09	66.2
tr:U9TTN8_RHIID	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESA09688.1};	23.40	312	175	13	14	286	52	338	8e-09	65.9
tr:X0HDP0_FUSOX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EXL70011.1};	23.21	293	192	9	14	290	21	296	8e-09	65.5
rs:XP_012061909	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic-like, partial [Atta cephalotes].	35.54	121	75	2	5	122	9	129	8e-09	62.8
tr:W9LRQ6_FUSOX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EWZ81798.1};	22.87	293	193	9	14	290	21	296	9e-09	65.5
rs:XP_010758509	hypothetical protein PADG_02562 [Paracoccidioides brasiliensis Pb18].	21.78	303	177	10	22	286	26	306	9e-09	65.5
tr:A0A015JTN4_9GLOM	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NAD(+)) {ECO:0000313|EMBL:EXX72957.1};	23.40	312	175	13	14	286	47	333	9e-09	65.5
rs:XP_003351697	hypothetical protein SMAC_00239 [Sordaria macrospora k-hell].	23.22	323	187	12	2	284	53	354	1e-08	65.9
tr:W2Y6E8_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETP30581.1};	26.95	308	162	13	15	286	74	354	1e-08	65.5
rs:WP_045714510	methenyltetrahydrofolate cyclohydrolase, partial [Salmonella enterica].	70.00	40	12	0	249	288	1	40	1e-08	60.5
rs:WP_036502022	methenyltetrahydrofolate cyclohydrolase, partial [Nitrosococcus oceani].	44.62	65	36	0	1	65	1	65	1e-08	60.8
rs:XP_001262076	methylenetetrahydrofolate dehydrogenase [Neosartorya fischeri NRRL 181].	22.65	309	179	10	2	273	11	296	1e-08	65.1
tr:A0A0A1NHX8_9FUNG	SubName: Full=RMATCC62417_03382 protein {ECO:0000313|EMBL:CEG66880.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CEI99048.1};	21.68	309	191	12	2	286	3	284	1e-08	64.7
tr:G5RRU5_SALET	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EHD06285.1};	51.56	64	23	3	209	270	1	58	1e-08	60.8
rs:XP_009810447	PREDICTED: C-1-tetrahydrofolate synthase, cytoplasmic, partial [Gavia stellata].	56.86	51	22	0	243	293	2	52	1e-08	65.5
tr:A0A0D8XA69_DICVI	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:KJH40529.1};	46.03	63	32	1	188	250	5	65	2e-08	64.3
rs:WP_040025063	hypothetical protein [Streptomyces sp. 150FB].	54.90	51	21	1	245	293	4	54	2e-08	60.5
rs:XP_009895379	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial [Picoides pubescens].	25.53	188	128	4	59	244	65	242	2e-08	65.5
tr:G4UAW3_NEUT9	SubName: Full=Putative methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EGZ77011.1};	23.22	323	187	12	2	284	9	310	2e-08	64.7
tr:D8M2C9_BLAHO	SubName: Full=Singapore isolate B (sub-type 7) whole genome shotgun sequence assembly, scaffold_18 {ECO:0000313|EMBL:CBK22224.2};	27.33	172	102	3	83	235	33	200	2e-08	63.2
rs:XP_010195565	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial, partial [Colius striatus].	27.84	176	115	4	59	232	57	222	2e-08	65.1
tr:A0A0C2IQE5_9PEZI	SubName: Full=Methylenetetrahydrofolate dehydrogenase (NAD+) {ECO:0000313|EMBL:KIH91261.1};	24.42	303	167	11	31	292	38	319	2e-08	64.3
tr:G1NJ63_MELGA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMGAP00000013349}; Flags: Fragment;	24.79	238	163	5	59	294	43	266	2e-08	65.1
tr:X1IGP2_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S24364 {ECO:0000313|EMBL:GAH81561.1}; Flags: Fragment;	64.44	45	16	0	249	293	1	45	2e-08	59.7
rs:WP_029980862	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Prochlorococcus sp. scB245a_518D8].	37.35	83	52	0	6	88	5	87	2e-08	60.5
tr:L7J7D9_MAGOP	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:ELQ64033.1};	24.51	306	160	11	12	271	16	296	2e-08	64.3
tr:F9FRM8_FUSOF	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGU80410.1};	23.21	293	192	9	14	290	363	638	2e-08	65.1
tr:X0EYI1_FUSOX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EXL40306.1};	22.87	293	193	9	14	290	21	296	2e-08	64.3
rs:XP_012755252	hypothetical protein SAMD00019534_053270 [Acytostelium subglobosum LB1].	24.76	315	176	10	6	286	15	302	2e-08	64.3
rs:WP_038817645	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas syringae].	64.29	42	15	0	249	290	8	49	3e-08	59.7
rs:WP_047158712	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Trichodesmium erythraeum].	50.85	59	29	0	5	63	6	64	3e-08	60.1
rs:XP_011392869	methylenetetrahydrofolate dehydrogenase, variant [Neurospora crassa OR74A].	23.22	323	187	12	2	284	9	310	3e-08	64.3
rs:XP_003839211	similar to methylenetetrahydrofolate dehydrogenase [Leptosphaeria maculans JN3].	24.25	301	159	12	21	293	22	281	3e-08	63.9
tr:U7PXI8_SPOS1	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ERT00318.1};	24.42	303	167	11	31	292	38	319	3e-08	63.9
tr:C6HLF7_AJECH	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EER39094.1};	21.45	303	178	10	22	286	28	308	3e-08	63.9
rs:XP_005425727	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial-like [Geospiza fortis].	23.44	273	177	8	15	284	125	368	3e-08	64.7
tr:T1AYU0_9ZZZZ	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase domain protein {ECO:0000313|EMBL:EQD62707.1}; EC=6.3.4.3 {ECO:0000313|EMBL:EQD62707.1}; Flags: Fragment;	69.05	42	13	0	249	290	3	44	4e-08	59.3
rs:XP_009855840	hypothetical protein NEUTE1DRAFT_90232 [Neurospora tetrasperma FGSC 2508].	23.22	323	187	12	2	284	9	310	4e-08	63.9
rs:XP_009812177	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial-like, partial [Gavia stellata].	26.32	228	140	7	59	284	73	274	4e-08	64.3
rs:XP_012404855	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial [Sarcophilus harrisii].	25.79	221	152	5	34	252	48	258	5e-08	64.3
tr:N4TID5_FUSC1	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:ENH62374.1};	22.46	285	182	8	14	290	21	274	5e-08	63.2
rs:XP_010034516	PREDICTED: bifunctional protein FolD 1, mitochondrial-like [Eucalyptus grandis].	33.67	98	65	0	2	99	66	163	5e-08	61.2
tr:X1RVF9_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_L05182 {ECO:0000313|EMBL:GAI84658.1}; Flags: Fragment;	65.00	40	14	0	252	291	1	40	5e-08	58.9
rs:XP_001213946	methylenetetrahydrofolate dehydrogenase [Aspergillus terreus NIH2624].	21.77	294	192	8	2	273	11	288	5e-08	63.5
tr:X0BI57_FUSOX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EXK81835.1};	22.87	293	193	9	14	290	21	296	5e-08	63.2
rs:XP_002997657	tetrahydrofolate dehydrogenase [Phytophthora infestans T30-4].	25.97	308	165	13	15	286	22	302	5e-08	63.2
tr:A0A098DDQ6_GIBZA	SubName: Full=Fusarium graminearum chromosome 1, complete genome {ECO:0000313|EMBL:CEF76081.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblFungi:CEF76081};	23.37	291	190	9	14	288	21	294	5e-08	63.2
rs:XP_010127805	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial-like, partial [Chlamydotis macqueenii].	25.32	237	149	6	59	293	64	274	5e-08	63.5
rs:XP_008081322	Aminoacid dehydrogenase-like, N-terminal [Glarea lozoyensis ATCC 20868].	24.50	298	163	11	22	279	25	300	5e-08	63.2
tr:X7YJQ3_MYCXE	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EUA07056.1};	42.86	77	36	2	216	292	1	69	5e-08	59.3
tr:A0A0D2I7D1_9EURO	SubName: Full=Unplaced genomic scaffold supercont1.36, whole genome shotgun sequence {ECO:0000313|EMBL:KIX93136.1};	24.07	295	162	13	31	286	37	308	5e-08	63.2
rs:XP_012744127	hypothetical protein GMDG_05696 [Pseudogymnoascus destructans 20631-21].	23.29	322	185	12	2	286	9	305	5e-08	63.2
rs:XP_007788515	putative methylenetetrahydrofolate dehydrogenase protein [Eutypa lata UCREL1].	25.37	335	189	14	2	295	8	322	5e-08	63.2
rs:XP_002364997	methylenetetrahydrofolate dehydrogenase, putative [Toxoplasma gondii ME49].	34.02	97	60	1	141	237	343	435	6e-08	63.9
tr:G3W9I4_SARHA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSHAP00000012089}; Flags: Fragment;	25.84	209	144	4	34	240	28	227	6e-08	63.9
tr:T4ZYN7_OPHSC	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EQK98254.1};	26.01	323	178	13	2	284	9	310	6e-08	63.2
tr:W9KFU5_FUSOX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EWZ40830.1};	22.87	293	193	9	14	290	21	296	6e-08	63.2
tr:A0A086M819_TOXGO	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain-containing protein {ECO:0000313|EMBL:KFG65037.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KFG65037.1}; Flags: Fragment;	34.02	97	60	1	141	237	273	365	6e-08	63.5
tr:A0A016PEV2_GIBZA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYB24210.1};	23.37	291	190	10	14	288	21	294	6e-08	63.2
tr:A0A0C3M0D9_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIO27112.1};	23.77	345	181	13	4	284	14	340	6e-08	63.2
rs:WP_003407852	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Pseudomonas syringae].	45.05	91	49	1	1	91	1	90	7e-08	59.3
rs:XP_009667015	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial [Struthio camelus australis].	26.14	241	142	7	59	293	58	268	7e-08	63.5
tr:A0A086QLM3_TOXGO	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain-containing protein {ECO:0000313|EMBL:KFH13505.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KFH13505.1};	34.02	97	60	1	141	237	564	656	7e-08	63.5
tr:A0A086LA23_TOXGO	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain-containing protein {ECO:0000313|EMBL:KFG53491.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KFG53491.1};	34.02	97	60	1	141	237	580	672	7e-08	63.5
rs:XP_007892608	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial [Callorhinchus milii].	24.79	238	161	7	60	293	4	227	7e-08	63.5
tr:S8F6Z6_TOXGO	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain-containing protein {ECO:0000313|EMBL:EPT29278.1}; EC=1.5.1.5 {ECO:0000313|EMBL:EPT29278.1};	34.02	97	60	1	141	237	564	656	8e-08	63.5
rs:XP_004935674	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X3 [Gallus gallus].	25.90	278	174	9	10	284	37	285	8e-08	63.5
tr:A0A086PKG3_TOXGO	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain-containing protein {ECO:0000313|EMBL:KFH00845.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KFH00845.1};	34.02	97	60	1	141	237	576	668	8e-08	63.5
rs:XP_009988258	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial, partial [Tauraco erythrolophus].	28.98	176	113	4	59	232	95	260	8e-08	63.5
rs:WP_029738013	MULTISPECIES: hypothetical protein, partial [unclassified Cloacimonetes].	34.33	134	70	5	160	290	1	119	8e-08	59.7
tr:Q3YBP5_9MYCO	SubName: Full=FolD {ECO:0000313|EMBL:AAZ76624.1}; Flags: Fragment;	50.00	72	28	2	215	286	1	64	8e-08	58.9
tr:A0A0C2DKP1_9BILA	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein {ECO:0000313|EMBL:KIH63127.1};	32.39	142	75	4	1	123	1	140	8e-08	60.1
rs:XP_004935676	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X5 [Gallus gallus].	25.90	278	174	9	10	284	37	285	9e-08	63.2
rs:XP_004935677	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X6 [Gallus gallus].	25.90	278	174	9	10	284	37	285	9e-08	63.2
rs:XP_001398040	methylenetetrahydrofolate dehydrogenase [NAD+] [Aspergillus niger CBS 513.88].	22.83	311	177	11	2	273	11	297	9e-08	62.8
tr:U3KCM2_FICAL	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFALP00000012776}; Flags: Fragment;	24.58	236	152	6	59	294	86	295	9e-08	63.2
rs:XP_005043934	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial [Ficedula albicollis].	24.58	236	152	6	59	294	50	259	9e-08	63.2
rs:XP_009093571	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial [Serinus canaria].	25.69	253	157	8	34	284	57	280	9e-08	63.2
tr:M8A864_TRIUA	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:EMS56644.1}; SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:TRIUR3_12177-P1};	33.98	103	68	0	1	103	71	173	9e-08	60.5
rs:XP_002793292	methylenetetrahydrofolate dehydrogenase [Paracoccidioides sp. 'lutzii' Pb01].	24.73	182	114	4	22	184	26	203	9e-08	62.4
rs:XP_007373043	hypothetical protein SPAPADRAFT_58844 [Spathaspora passalidarum NRRL Y-27907].	28.07	171	100	5	34	185	38	204	1e-07	62.4
rs:XP_010223110	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial, partial [Tinamus guttatus].	24.90	241	150	6	56	293	50	262	1e-07	63.2
rs:XP_008604197	methylenetetrahydrofolate dehydrogenase (NAD+) [Saprolegnia diclina VS20].	26.39	288	159	13	33	286	33	301	1e-07	62.4
tr:V9KD80_CALMI	SubName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial-like protein {ECO:0000313|EMBL:AFO95863.1}; Flags: Fragment;	24.79	238	161	7	60	293	83	306	1e-07	63.2
rs:WP_022026359	bifunctional protein FolD [Dialister invisus CAG:218].	43.48	69	32	1	224	292	1	62	1e-07	58.2
rs:XP_419672	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X2 [Gallus gallus].	28.51	228	135	7	59	284	48	249	1e-07	62.8
tr:D9W648_9ACTO	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EFL20404.1};	52.38	63	22	3	224	286	1	55	1e-07	58.5
tr:W6MX35_9ASCO	SubName: Full=Genomic scaffold, Kuraishia_capsulata_scaffold_5 {ECO:0000313|EMBL:CDK28200.1};	24.05	316	181	12	1	279	1	294	1e-07	62.0
rs:XP_007292275	hypothetical protein MBM_04386 [Marssonina brunnea f. sp. 'multigermtubi' MB_m1].	26.05	311	167	15	11	280	29	317	1e-07	62.0
tr:J4U874_TRIAS	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJT46635.1};	22.07	290	171	9	39	292	84	354	1e-07	62.4
rs:XP_009598121	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X1 [Nicotiana tomentosiformis].	32.67	101	68	0	2	102	67	167	1e-07	60.1
rs:XP_009598122	PREDICTED: bifunctional protein FolD 1, mitochondrial-like isoform X2 [Nicotiana tomentosiformis].	32.67	101	68	0	2	102	66	166	2e-07	60.1
tr:A0A0A9WBI5_LYGHE	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:JAG04776.1}; Flags: Fragment;	35.61	132	82	3	4	133	2	132	2e-07	59.3
tr:A0A084PQM4_STACH	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFA52509.1};	24.88	205	129	5	2	185	9	209	2e-07	61.6
tr:M3W0S2_FELCA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFCAP00000003388}; Flags: Fragment;	21.92	260	192	4	34	291	40	290	2e-07	62.4
rs:XP_007737326	methylenetetrahydrofolate dehydrogenase (NAD+) [Capronia epimyces CBS 606.96].	21.81	298	168	10	32	286	33	308	2e-07	61.6
tr:W4X9E2_ATTCE	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:ACEP28048-PA};	35.34	116	72	2	10	122	2	117	2e-07	58.5
rs:XP_001746331	hypothetical protein [Monosiga brevicollis MX1].	24.28	276	168	11	2	242	25	294	2e-07	62.0
tr:A0A0C9MVL0_9FUNG	SubName: Full=DNA, scaffold: scf_mam1_v10165, strain NBRC 6742, whole genome shotgun sequence {ECO:0000313|EMBL:GAN07537.1};	23.24	327	175	14	2	286	3	295	2e-07	61.6
tr:W1XAG5_9ZZZZ	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:ETJ27332.1}; Flags: Fragment;	35.00	80	48	1	121	200	1	76	2e-07	57.8
tr:S7IY33_CHLPS	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein {ECO:0000313|EMBL:EPP32652.1};	65.85	41	14	0	251	291	1	41	2e-07	57.0
rs:WP_031326088	methenyltetrahydrofolate cyclohydrolase, partial [Pseudomonas syringae].	45.68	81	43	1	1	81	1	80	2e-07	57.8
rs:XP_008877007	hypothetical protein H310_11921 [Aphanomyces invadans].	26.99	289	156	15	33	286	28	296	2e-07	61.2
tr:A0A0D2MUA5_9CHLO	SubName: Full=Strain SAG 48.87 unplaced genomic scaffold scaffold00508, whole genome shotgun sequence {ECO:0000313|EMBL:KIZ04092.1}; EC=6.3.4.3 {ECO:0000313|EMBL:KIZ04092.1};	42.86	70	40	0	36	105	14	83	2e-07	58.2
tr:S3CNX4_OPHP1	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EPE08223.1};	26.19	294	155	13	32	284	39	311	2e-07	61.2
rs:XP_010172641	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial-like, partial [Caprimulgus carolinensis].	26.58	237	147	7	59	293	62	273	2e-07	62.0
tr:A0A099ZQX3_TINGU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGL84266.1}; Flags: Fragment;	26.67	180	120	4	56	233	37	206	3e-07	62.0
rs:WP_038855680	methenyltetrahydrofolate cyclohydrolase, partial [Mycobacterium avium].	44.00	75	34	2	217	291	2	68	3e-07	57.4
rs:XP_010705520	PREDICTED: LOW QUALITY PROTEIN: monofunctional C1-tetrahydrofolate synthase, mitochondrial [Meleagris gallopavo].	25.62	242	160	7	8	246	35	259	3e-07	62.0
tr:I1ZES6_VIBAL	SubName: Full=Putative methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:AFJ22784.1}; Flags: Fragment;	47.54	61	32	0	1	61	1	61	3e-07	57.0
tr:A0A0D2ETB1_9EURO	SubName: Full=Unplaced genomic scaffold supercont1.6, whole genome shotgun sequence {ECO:0000313|EMBL:KIW77457.1};	23.63	292	161	13	34	286	40	308	3e-07	61.2
tr:S6PH93_PSESF	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EPM93305.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EPM93305.1}; Flags: Fragment;	65.85	41	14	0	254	294	1	41	3e-07	56.6
tr:A0A077LZ08_9MICO	SubName: Full=Methylenetetrahydrofolate dehydrogenase methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:CCH77179.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CCH77179.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CCH77179.1};	41.10	73	33	1	211	283	1	63	3e-07	57.4
tr:A0A0D2CGN2_9EURO	SubName: Full=Strain CBS 83496 unplaced genomic scaffold supercont1.7, whole genome shotgun sequence {ECO:0000313|EMBL:KIW22704.1};	23.39	295	164	12	31	286	37	308	3e-07	60.8
rs:XP_004029508	PREDICTED: uncharacterized protein LOC101146809 [Gorilla gorilla gorilla].	71.79	39	11	0	253	291	226	264	3e-07	60.5
rs:WP_001070302	hypothetical protein, partial [Leptospira interrogans].	39.34	61	37	0	1	61	1	61	3e-07	57.0
tr:K1W8V2_TRIAC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKD05233.1};	21.72	290	172	9	39	292	84	354	4e-07	60.8
tr:A0A0A1NVN6_9FUNG	SubName: Full=Putative Formate-tetrahydrofolate ligase {ECO:0000313|EMBL:CEJ03488.1};	62.22	45	17	0	249	293	2	46	5e-07	61.2
tr:F2QNF3_PICP7	SubName: Full=MTD1 protein {ECO:0000313|EMBL:CCA36386.1}; EC=1.5.1.15 {ECO:0000313|EMBL:CCA36386.1};	21.57	306	181	11	11	279	10	293	5e-07	60.5
tr:T1A607_9ZZZZ	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EQD36314.1}; Flags: Fragment;	27.35	117	80	2	78	194	49	160	5e-07	58.2
rs:XP_007667413	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, partial [Ornithorhynchus anatinus].	33.09	139	75	4	95	215	62	200	5e-07	59.3
rs:XP_003237309	methylenetetrahydrofolate dehydrogenase [Trichophyton rubrum CBS 118892].	23.20	181	117	3	22	184	27	203	5e-07	60.5
rs:WP_036639804	methenyltetrahydrofolate cyclohydrolase, partial [Paenirhodobacter enshiensis].	63.64	44	16	0	245	288	2	45	5e-07	56.2
tr:A0A024GSQ7_9STRA	SubName: Full=Albugo candida WGS project CAIX00000000 data, strain Ac Nc2, contig AcNc2_CONTIG_366_length_25024 {ECO:0000313|EMBL:CCI49927.1};	24.77	327	177	14	1	286	1	299	5e-07	60.1
rs:WP_037696372	methylenetetrahydrofolate dehydrogenase, partial [Streptomyces scabiei].	23.48	247	154	9	46	286	3	220	6e-07	59.3
rs:XP_002172379	methylenetetrahydrofolate reductase [Schizosaccharomyces japonicus yFS275].	23.08	286	163	10	40	289	45	309	6e-07	60.1
rs:WP_040684856	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Nocardiopsis halotolerans].	46.15	65	28	1	228	292	3	60	6e-07	56.2
rs:XP_003172554	methylenetetrahydrofolate dehydrogenase [Microsporum gypseum CBS 118893].	25.82	182	111	5	22	184	27	203	6e-07	60.1
rs:XP_005488191	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial-like [Zonotrichia albicollis].	24.77	222	151	6	15	233	80	288	7e-07	60.8
rs:XP_009488759	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial-like, partial [Pelecanus crispus].	32.33	133	85	3	56	185	79	209	7e-07	59.7
tr:K2C1S0_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKD79821.1}; Flags: Fragment;	33.86	127	66	4	160	286	23	131	8e-07	57.4
tr:S6UP45_PSESF	SubName: Full=Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EPN57809.1}; EC=3.5.4.9 {ECO:0000313|EMBL:EPN57809.1}; Flags: Fragment;	43.94	66	37	0	59	124	4	69	8e-07	55.8
tr:H2Z0I4_CIOSA	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAVP00000011096};	81.82	33	6	0	259	291	4	36	8e-07	57.0
rs:WP_046703972	methylenetetrahydrofolate dehydrogenase, partial [Streptomyces europaeiscabiei].	23.48	247	154	9	46	286	3	220	9e-07	58.9
rs:XP_002383442	methylenetetrahydrofolate dehydrogenase, putative [Aspergillus flavus NRRL3357].	22.97	296	168	10	35	292	34	307	9e-07	59.7
rs:WP_004836244	methenyltetrahydrofolate cyclohydrolase [Anaerococcus tetradius].	21.77	271	188	7	15	283	9	257	9e-07	58.9
tr:X1BT86_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S02038 {ECO:0000313|EMBL:GAG75361.1}; Flags: Fragment;	35.37	82	53	0	4	85	3	84	9e-07	56.2
rs:XP_003021460	hypothetical protein TRV_04433 [Trichophyton verrucosum HKI 0517].	22.65	181	118	3	22	184	27	203	9e-07	59.7
tr:T1CB19_9ZZZZ	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase domain protein {ECO:0000313|EMBL:EQD63710.1}; EC=6.3.4.3 {ECO:0000313|EMBL:EQD63710.1}; Flags: Fragment;	79.31	29	6	0	260	288	1	29	9e-07	55.1
tr:A0A0D2FDP2_9EURO	SubName: Full=Capronia semiimmersa strain CBS 27337 unplaced genomic scaffold supercont1.5, whole genome shotgun sequence {ECO:0000313|EMBL:KIW64950.1};	22.95	292	158	12	39	286	66	334	9e-07	59.7
rs:XP_002188396	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial [Taeniopygia guttata].	24.54	273	174	9	15	284	8	251	1e-06	60.1
rs:XP_003769595	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial [Sarcophilus harrisii].	26.24	221	151	5	34	252	48	258	1e-06	60.1
rs:XP_008175623	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X3 [Chrysemys picta bellii].	23.53	238	160	7	59	293	94	312	1e-06	60.1
rs:XP_002489564	NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase [Komagataella pastoris GS115].	21.57	306	181	11	11	279	85	368	1e-06	59.3
tr:V6KWU2_STRRC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EST35886.1};	59.52	42	17	0	252	293	12	53	1e-06	55.1
rs:XP_008175613	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X1 [Chrysemys picta bellii].	23.53	238	160	7	59	293	94	312	1e-06	59.7
rs:WP_020055854	hypothetical protein [alpha proteobacterium SCGC AAA015-O19].	58.14	43	18	0	249	291	34	76	1e-06	55.8
tr:H0ZM37_TAEGU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTGUP00000011660}; Flags: Fragment;	23.76	202	143	4	34	233	18	210	1e-06	59.7
rs:XP_001794522	hypothetical protein SNOG_04095 [Phaeosphaeria nodorum SN15].	22.77	303	162	11	21	290	22	285	2e-06	58.5
rs:WP_040805029	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [gamma proteobacterium IMCC1989].	35.90	78	40	1	216	293	1	68	2e-06	55.1
rs:XP_002843819	methylenetetrahydrofolate dehydrogenase [Arthroderma otae CBS 113480].	24.86	185	112	5	22	184	27	206	2e-06	58.9
rs:XP_002898827	methylenetetrahydrofolate dehydrogenase [NAD+], putative [Phytophthora infestans T30-4].	25.75	299	154	13	15	286	22	279	2e-06	58.5
tr:V7FN95_9RHIZ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESX80595.1};	52.38	63	26	2	231	293	1	59	2e-06	55.1
rs:XP_009873511	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial-like, partial [Apaloderma vittatum].	28.98	176	113	5	59	232	82	247	2e-06	59.3
tr:A0A0A2LGF6_PENIT	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase {ECO:0000313|EMBL:KGO78296.1};	21.61	310	182	9	2	273	11	297	2e-06	58.5
tr:M0UW56_HORVD	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:MLOC_14916.2};	36.56	93	59	0	3	95	2	94	2e-06	55.5
tr:A0A024GUC6_9STRA	SubName: Full=Albugo candida WGS project CAIX00000000 data, strain Ac Nc2, contig AcNc2_CONTIG_366_length_25024 {ECO:0000313|EMBL:CCI49928.1};	24.62	325	176	14	3	286	2	298	2e-06	58.2
rs:XP_747335	methylenetetrahydrofolate dehydrogenase [Aspergillus fumigatus Af293].	21.91	324	178	12	2	288	11	296	2e-06	58.2
tr:T1C6N1_9ZZZZ	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase domain protein {ECO:0000313|EMBL:EQD61765.1}; EC=6.3.4.3 {ECO:0000313|EMBL:EQD61765.1}; Flags: Fragment;	43.94	66	37	0	1	66	14	79	2e-06	55.1
tr:X6LR77_RETFI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETO04144.1}; Flags: Fragment;	33.66	101	50	2	141	228	25	121	2e-06	55.8
rs:XP_007602538	hypothetical protein CFIO01_05718 [Colletotrichum fioriniae PJ7].	22.83	311	166	9	19	296	36	305	2e-06	58.2
tr:A0A081RKS9_9ARCH	SubName: Full=Bifunctional protein FolD {ECO:0000313|EMBL:KEQ55802.1}; EC=1.5.1.5 {ECO:0000313|EMBL:KEQ55802.1}; Flags: Fragment;	64.86	37	13	0	256	292	1	37	2e-06	53.9
rs:XP_010182925	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial-like, partial [Mesitornis unicolor].	30.56	144	92	3	59	200	16	153	3e-06	56.2
tr:X1NX20_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S05545 {ECO:0000313|EMBL:GAI23209.1}; Flags: Fragment;	61.90	42	16	0	252	293	1	42	3e-06	53.9
tr:A0A0D9NAN5_ASPFL	SubName: Full=Tetrahydrofolate dehydrogenasecyclohydrolase catalytic domain protein {ECO:0000313|EMBL:KJJ37177.1};	22.64	296	169	10	35	292	34	307	3e-06	58.2
rs:WP_031998951	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Acinetobacter baumannii].	37.50	88	53	2	3	89	32	118	3e-06	55.5
rs:WP_037137271	hypothetical protein [Rhizobium sp. CF394].	62.50	40	15	0	250	289	1	40	3e-06	54.3
rs:XP_009840443	hypothetical protein H257_14368 [Aphanomyces astaci].	25.32	316	179	13	6	286	3	296	4e-06	57.8
rs:WP_041875495	methenyltetrahydrofolate cyclohydrolase, partial [Verrucomicrobia bacterium SCGC AAA164-O14].	53.57	56	25	1	3	58	2	56	4e-06	53.9
rs:WP_029980290	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Prochlorococcus sp. scB245a_519E23].	44.64	56	31	0	47	102	1	56	4e-06	53.9
tr:I8A319_ASPO3	SubName: Full=Methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase {ECO:0000313|EMBL:EIT79317.1};	25.60	168	103	4	35	184	34	197	4e-06	57.4
tr:Q2UUX1_ASPOR	SubName: Full=Putative uncharacterized protein AO090009000139 {ECO:0000313|EMBL:BAE54644.1};	25.60	168	103	4	35	184	34	197	4e-06	57.4
tr:X1QUA7_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_C02528 {ECO:0000313|EMBL:GAI71853.1};	38.10	63	39	0	34	96	3	65	5e-06	53.9
tr:F4QPR0_9CAUL	SubName: Full=FolD protein {ECO:0000313|EMBL:EGF90197.1};	63.16	38	14	0	251	288	1	38	5e-06	53.1
tr:U4Q864_TEPAE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CDI40430.1}; EC=1.5.1.5 {ECO:0000313|EMBL:CDI40430.1}; EC=3.5.4.9 {ECO:0000313|EMBL:CDI40430.1};	36.78	87	54	1	3	89	2	87	6e-06	53.9
rs:WP_002299876	5,10-methylene-tetrahydrofolate dehydrogenase, partial [Streptococcus mutans].	40.66	91	54	0	4	94	3	93	6e-06	54.3
tr:A0A0C3GKY1_9HOMO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KIM91261.1};	24.43	221	116	6	12	184	11	228	6e-06	57.4
tr:W7T6I6_9STRA	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EWM22137.1};	24.85	330	170	17	6	286	23	323	6e-06	57.4
rs:WP_044897006	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Phascolarctobacterium sp. CAG:266].	30.84	107	73	1	1	107	1	106	6e-06	54.3
rs:XP_005507767	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial-like [Columba livia].	24.69	239	148	8	59	293	62	272	6e-06	57.8
rs:XP_011121831	hypothetical protein AOL_s00078g266 [Arthrobotrys oligospora ATCC 24927].	22.70	304	166	12	31	284	43	327	6e-06	57.0
tr:A0A009M3A9_ACIBA	SubName: Full=Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein {ECO:0000313|EMBL:EXB53035.1}; Flags: Fragment;	37.50	88	53	2	3	89	2	88	6e-06	53.9
rs:XP_659128	hypothetical protein AN1524.2 [Aspergillus nidulans FGSC A4].	22.95	183	116	4	22	184	27	204	6e-06	57.0
rs:XP_005518698	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial-like [Pseudopodoces humilis].	22.71	273	179	8	15	284	19	262	7e-06	57.8
rs:XP_518807	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X2 [Pan troglodytes].	23.76	202	143	5	34	233	98	290	8e-06	57.4
tr:X1B5F5_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S02192 {ECO:0000313|EMBL:GAG76502.1}; Flags: Fragment;	59.52	42	17	0	252	293	1	42	8e-06	52.8
rs:XP_011534033	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X5 [Homo sapiens].	23.76	202	143	5	34	233	32	224	8e-06	57.4
rs:XP_005266964	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X2 [Homo sapiens].	23.76	202	143	5	34	233	98	290	8e-06	57.4
tr:X1VK30_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S12H4_S13630 {ECO:0000313|EMBL:GAJ08320.1}; Flags: Fragment;	73.53	34	9	0	257	290	1	34	8e-06	52.8
rs:XP_010329736	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial [Saimiri boliviensis boliviensis].	23.15	203	143	5	34	233	32	224	9e-06	57.4
tr:G5LKA8_SALET	SubName: Full=Methylenetetrahydrofolate dehydrogenase {ECO:0000313|EMBL:EHC44114.1}; Flags: Fragment;	68.42	38	10	1	252	289	1	36	9e-06	52.8
gp:HH961832_1	Sequence 91 from Patent EP1572118. [Homo sapiens]	23.76	202	143	5	34	233	37	229	9e-06	57.4
rs:XP_009450510	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X4 [Pan troglodytes].	23.76	202	143	5	34	233	45	237	9e-06	57.4
rs:XP_009464611	PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial [Nipponia nippon].	27.63	228	137	7	59	284	129	330	9e-06	57.4
sp:C1TM_HUMAN	RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;	23.76	202	143	5	34	233	98	290	1e-05	57.0
rs:WP_040690311	5,10-methylene-tetrahydrofolate cyclohydrolase, partial [Nocardiopsis lucentensis].	32.22	90	61	0	43	132	1	90	1e-05	53.5
gp:BC110319_1	MTHFD1L protein [Homo sapiens]	23.76	202	143	5	34	233	20	212	1e-05	57.0