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TARA_ERS492160_N000154_42 / Result of BLASTP

browse BLASTP result of all genes from this scaffold

subject	subject definition	idt	len	mis	gap	q.start	q.end	s.start	s.end	evalue	bit.score
subject	subject definition	idt	len	mis	gap	q.start	q.end	s.start	s.end	evalue	bit.score
rs:WP_045391803	hypothetical protein [Vibrio rotiferianus].	37.12	563	336	11	8	561	5	558	6e-114	365
rs:WP_021817730	hypothetical protein [Halomonas sp. BJGMM-B45].	34.92	567	323	14	8	548	6	552	4e-95	318
rs:WP_018347287	MULTISPECIES: DNA topoisomerase III [Gallibacterium].	34.40	596	342	15	7	581	4	571	4e-95	317
rs:WP_039148623	DNA topoisomerase III [Gallibacterium anatis].	35.47	547	318	13	7	539	4	529	6e-95	317
rs:WP_039158592	DNA topoisomerase III [Gallibacterium anatis].	34.23	596	343	15	7	581	4	571	8e-95	316
rs:WP_035415424	DNA topoisomerase III [Chromohalobacter israelensis].	34.69	565	327	14	8	548	6	552	8e-95	317
rs:WP_039081120	DNA topoisomerase III [Gallibacterium anatis].	34.23	596	343	15	7	581	4	571	4e-94	314
tr:A0A0A5IJ55_CITKO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.56	544	329	10	8	539	5	533	5e-94	313
rs:WP_039145124	DNA topoisomerase III [Gallibacterium anatis].	33.28	595	350	13	7	581	4	571	7e-94	313
rs:WP_013745196	DNA topoisomerase III [Gallibacterium anatis].	34.43	546	325	11	7	539	4	529	8e-94	313
rs:WP_039089672	DNA topoisomerase III [Gallibacterium anatis].	33.28	595	350	13	7	581	4	571	2e-93	312
rs:WP_046481302	DNA topoisomerase III [Citrobacter amalonaticus].	34.25	546	339	10	8	544	5	539	4e-93	310
rs:WP_023004936	DNA topoisomerase III [Halomonas sp. PBN3].	35.14	552	331	11	7	544	4	542	5e-93	311
rs:WP_032734403	DNA topoisomerase III [Klebsiella oxytoca].	34.01	544	332	10	8	539	5	533	2e-92	308
rs:WP_031590979	DNA topoisomerase III [Klebsiella pneumoniae].	34.12	548	326	10	8	539	5	533	2e-92	308
rs:WP_009654423	DNA topoisomerase III [Klebsiella sp. OBRC7].	33.94	548	327	10	8	539	5	533	4e-92	308
rs:WP_032629416	DNA topoisomerase III [Pseudomonas syringae].	33.75	560	338	14	8	550	5	548	6e-92	309
rs:WP_032724076	DNA topoisomerase III [Enterobacter aerogenes].	33.82	544	333	10	8	539	5	533	6e-92	307
rs:WP_039016632	DNA topoisomerase III [Cupriavidus sp. SHE].	34.28	563	334	12	8	552	5	549	9e-92	308
rs:WP_004856680	DNA topoisomerase III [Klebsiella oxytoca].	34.12	554	335	12	8	546	5	543	1e-91	308
rs:WP_020846019	DNA topoisomerase III [Salmonella bongori].	34.19	544	331	10	8	539	5	533	2e-91	306
rs:WP_023155789	DNA topoisomerase III [Escherichia coli].	33.52	543	336	9	8	539	5	533	2e-91	306
rs:WP_035474305	DNA topoisomerase III [Gammaproteobacteria bacterium MFB021].	35.45	567	321	16	7	548	5	551	3e-91	308
rs:WP_001728503	DNA topoisomerase III [Salmonella enterica].	33.64	544	334	10	8	539	5	533	3e-91	305
rs:WP_003413130	DNA topoisomerase III [Pseudomonas syringae].	33.63	562	336	13	8	549	5	549	4e-91	307
rs:WP_033567093	DNA topoisomerase III [Salmonella enterica].	35.48	544	317	12	8	531	5	534	4e-91	307
rs:WP_039575248	DNA topoisomerase III [Xanthomonas axonopodis].	34.28	566	327	15	8	549	5	549	4e-91	307
rs:WP_014908052	DNA topoisomerase III [Klebsiella pneumoniae].	33.76	548	328	10	8	539	5	533	4e-91	305
rs:WP_012315261	DNA topoisomerase III [Pseudomonas putida].	34.46	560	331	14	7	548	4	545	4e-91	306
rs:WP_023434789	DNA topoisomerase III [Pseudomonas aeruginosa].	33.69	567	336	13	8	552	5	553	4e-91	307
rs:WP_031423960	DNA topoisomerase III [Xanthomonas axonopodis].	33.63	562	336	13	8	549	5	549	5e-91	306
rs:WP_044349383	DNA topoisomerase III [Raoultella ornithinolytica].	33.39	554	339	12	8	546	5	543	7e-91	306
rs:WP_023218679	DNA topoisomerase III [Salmonella enterica].	34.41	555	332	14	8	546	5	543	7e-91	306
rs:WP_013692761	DNA topoisomerase III [Pseudomonas brassicacearum].	33.81	559	342	12	8	552	5	549	7e-91	306
rs:WP_023182587	DNA topoisomerase III [Salmonella enterica].	34.33	536	325	10	8	531	5	525	7e-91	304
rs:WP_038275044	DNA topoisomerase III [Yersinia ruckeri].	34.70	559	334	13	7	549	4	547	8e-91	306
rs:WP_047366551	DNA topoisomerase III [Enterobacter sp. GN02226].	33.64	544	334	10	8	539	5	533	8e-91	304
rs:WP_027912503	DNA topoisomerase III [Pseudomonas sp. URIL14HWK12:I7].	35.27	550	320	14	8	539	5	536	8e-91	306
rs:WP_039602441	DNA topoisomerase III [Pseudomonas putida].	34.29	560	332	14	7	548	4	545	1e-90	305
rs:WP_027962007	DNA topoisomerase III [Halomonas halodenitrificans].	34.78	552	333	11	7	544	4	542	1e-90	305
rs:WP_022960734	DNA topoisomerase III [Pseudomonas pelagia].	33.21	563	340	12	8	552	5	549	1e-90	305
rs:WP_045631099	DNA topoisomerase III [Enterobacter cloacae].	33.82	544	333	10	8	539	5	533	2e-90	303
rs:WP_035565616	DNA topoisomerase III [Halomonas sp. KO116].	34.96	552	322	10	8	539	5	539	2e-90	306
rs:WP_032191370	DNA topoisomerase III [Escherichia coli].	35.66	544	316	12	8	531	5	534	2e-90	305
rs:WP_016253291	MULTISPECIES: hypothetical protein [Proteobacteria].	33.93	563	336	13	8	552	5	549	2e-90	305
rs:WP_027597847	DNA topoisomerase III [Pseudomonas sp. MOIL14HWK12:I2].	33.57	569	333	13	8	552	5	552	2e-90	305
rs:WP_042133161	DNA topoisomerase III [Pseudomonas oryzihabitans].	33.39	569	334	13	8	552	5	552	2e-90	305
rs:WP_034000341	DNA topoisomerase III [Pseudomonas aeruginosa].	35.17	563	329	14	8	552	5	549	3e-90	305
rs:WP_023098636	hypothetical protein [Pseudomonas aeruginosa].	33.69	564	337	14	8	552	5	550	3e-90	305
rs:WP_033873156	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	33.57	566	337	13	8	552	5	552	3e-90	301
rs:WP_034021230	DNA topoisomerase III [Pseudomonas aeruginosa].	33.04	560	346	11	8	552	5	550	3e-90	305
rs:WP_012205960	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	35.17	563	329	14	8	552	5	549	3e-90	305
rs:WP_027603251	DNA topoisomerase III [Pseudomonas sp. LAMO17WK12:I2].	35.55	557	309	14	8	539	5	536	4e-90	304
rs:WP_046788273	DNA topoisomerase III [Pseudomonas putida].	33.93	560	334	14	7	548	4	545	4e-90	304
rs:WP_023912627	DNA topoisomerase III [Pseudomonas aeruginosa].	33.93	563	336	13	8	552	5	549	4e-90	304
rs:WP_013333796	DNA topoisomerase III [Halomonas elongata].	35.82	564	322	15	7	548	5	550	5e-90	304
rs:WP_043223335	DNA topoisomerase III [Bordetella hinzii].	33.98	568	338	14	4	552	1	550	5e-90	304
rs:WP_032214543	DNA topoisomerase III [Escherichia coli].	33.89	543	334	9	8	539	5	533	5e-90	302
rs:WP_027350505	DNA topoisomerase III [Halotalea alkalilenta].	33.98	568	338	14	4	552	1	550	5e-90	304
rs:WP_020207144	DNA topoisomerase III, partial [Cupriavidus sp. WS].	33.57	563	338	13	8	552	5	549	5e-90	301
rs:WP_045994683	DNA topoisomerase III [Halomonas sp. S2151].	34.78	552	333	12	7	544	4	542	6e-90	303
rs:WP_044061218	DNA topoisomerase III [Pseudomonas aeruginosa].	33.98	568	338	14	4	552	1	550	6e-90	304
rs:WP_003050384	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	33.51	567	337	13	8	552	5	553	6e-90	304
rs:WP_027601788	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	32.86	566	341	12	8	552	5	552	6e-90	304
rs:WP_034007122	DNA topoisomerase III [Pseudomonas aeruginosa].	33.81	565	337	12	8	552	5	552	6e-90	304
rs:WP_003090102	DNA topoisomerase III [Pseudomonas aeruginosa].	33.51	567	337	12	8	552	5	553	7e-90	304
rs:WP_047149922	DNA topoisomerase III [Pseudomonas sp. TJI-51].	34.46	560	331	14	7	548	4	545	7e-90	303
rs:WP_043955306	DNA topoisomerase III [Enterobacter sp. YD4].	33.46	544	335	12	8	539	5	533	7e-90	301
rs:WP_018715759	DNA topoisomerase III [Brachymonas chironomi].	33.51	567	337	13	8	552	5	553	8e-90	304
rs:WP_045331640	DNA topoisomerase III [Enterobacter cloacae].	33.64	544	334	11	8	539	5	533	8e-90	302
rs:WP_034947635	DNA topoisomerase III [Erwinia oleae].	35.05	562	328	15	7	549	4	547	9e-90	303
rs:WP_032942259	DNA topoisomerase III [Citrobacter freundii].	33.46	544	335	10	8	539	5	533	9e-90	301
rs:WP_013391789	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	33.75	566	336	13	8	552	5	552	1e-89	303
rs:WP_029887822	DNA topoisomerase III [Pseudomonas putida].	34.46	560	331	14	7	548	4	545	1e-89	303
rs:WP_039163724	DNA topoisomerase III [Gallibacterium anatis].	33.75	560	332	14	8	548	5	544	1e-89	303
tr:W4SCH7_9XANT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.45	562	337	13	8	549	5	549	1e-89	303
rs:WP_032718932	DNA topoisomerase III [Klebsiella oxytoca].	33.82	544	333	10	8	539	5	533	1e-89	301
rs:WP_003120035	DNA topoisomerase III [Pseudomonas aeruginosa].	33.21	563	340	12	8	552	5	549	1e-89	303
rs:WP_044340829	DNA topoisomerase III [Pseudomonas oryzihabitans].	33.39	569	334	13	8	552	5	552	1e-89	303
rs:WP_043861109	DNA topoisomerase III [Pseudomonas putida].	35.06	559	327	14	8	548	5	545	1e-89	302
tr:A0A0C6ES95_PSEAI	SubName: Full=Pseudomonas aeruginosa DNA, complete genome, strain: NCGM257 {ECO:0000313|EMBL:BAQ39233.1};	33.51	567	337	13	8	552	5	553	1e-89	303
rs:WP_042907306	DNA topoisomerase III [Gallibacterium anatis].	33.75	560	332	14	8	548	5	544	1e-89	303
rs:WP_000765275	DNA topoisomerase III [Escherichia coli].	34.41	555	332	14	8	546	5	543	2e-89	303
rs:WP_015601729	DNA topoisomerase III family protein [Burkholderia thailandensis].	33.75	566	336	13	8	552	5	552	2e-89	303
rs:WP_039011295	DNA topoisomerase III [Pseudomonas brassicacearum].	34.85	548	325	12	8	539	5	536	2e-89	302
rs:WP_023157825	DNA topoisomerase [Klebsiella pneumoniae].	34.23	555	333	14	8	546	5	543	2e-89	302
rs:WP_047050492	DNA topoisomerase III [Enterobacter aerogenes].	33.64	544	334	10	8	539	5	533	2e-89	300
rs:WP_012248046	DNA topoisomerase III [Bordetella petrii].	33.27	565	337	14	8	552	5	549	3e-89	302
rs:WP_024890123	DNA topoisomerase III [Luteimonas huabeiensis].	33.93	563	336	13	8	552	5	549	3e-89	302
rs:WP_014699279	DNA topoisomerase [Pectobacterium sp. SCC3193].	32.92	559	347	10	8	552	5	549	3e-89	302
rs:WP_025214466	DNA topoisomerase III [Pseudomonas brassicacearum].	35.39	551	319	15	8	539	5	537	3e-89	301
rs:WP_007160882	DNA topoisomerase III [Pseudomonas psychrotolerans].	33.22	569	335	12	8	552	5	552	3e-89	302
rs:WP_009618204	DNA topoisomerase III [Pseudomonas sp. M1].	33.98	568	338	14	4	552	1	550	3e-89	302
rs:WP_015869774	DNA topoisomerase III [Edwardsiella ictaluri].	35.32	538	321	12	8	531	5	529	3e-89	302
rs:WP_023082340	hypothetical protein [Pseudomonas aeruginosa].	34.10	563	335	13	8	552	5	549	3e-89	302
rs:WP_021205487	DNA topoisomerase III [Pseudomonas aeruginosa].	33.45	568	341	14	4	552	1	550	4e-89	302
rs:WP_043081838	DNA topoisomerase III [Pluralibacter gergoviae].	33.45	565	339	12	8	552	5	552	4e-89	301
rs:WP_023108431	hypothetical protein [Pseudomonas aeruginosa].	33.57	566	337	13	8	552	5	552	4e-89	301
rs:WP_033962290	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	33.57	566	337	13	8	552	5	552	4e-89	301
rs:WP_033937544	DNA topoisomerase III [Pseudomonas aeruginosa].	33.45	565	339	12	8	552	5	552	5e-89	301
rs:WP_035686649	DNA topoisomerase III [Avibacterium paragallinarum].	34.17	556	335	13	8	548	5	544	5e-89	301
rs:WP_042992894	DNA topoisomerase III [Bordetella bronchiseptica].	33.57	566	337	13	8	552	5	552	5e-89	301
rs:WP_023124756	hypothetical protein [Pseudomonas aeruginosa].	34.64	563	332	13	8	552	5	549	6e-89	301
rs:WP_034032722	DNA topoisomerase III [Pseudomonas aeruginosa].	34.64	563	332	13	8	552	5	549	6e-89	301
rs:WP_024763865	DNA topoisomerase III [Pseudomonas nitroreducens].	33.57	566	337	13	8	552	5	552	6e-89	301
rs:WP_003487097	DNA topoisomerase III [Xanthomonas citri].	33.27	565	340	13	7	552	4	550	7e-89	301
rs:WP_032670646	DNA topoisomerase III [Enterobacter cloacae].	33.64	544	334	10	8	539	5	533	7e-89	299
rs:WP_023087320	hypothetical protein [Pseudomonas aeruginosa].	33.57	566	337	13	8	552	5	552	7e-89	301
rs:WP_029578156	DNA topoisomerase III [Bordetella hinzii].	33.63	568	340	14	4	552	1	550	7e-89	301
rs:WP_045292289	DNA topoisomerase III [Enterobacter sp. 42324].	33.46	544	335	10	8	539	5	533	8e-89	299
rs:WP_024617231	DNA topoisomerase III [Pseudomonas fluorescens].	33.09	559	346	11	8	552	5	549	9e-89	301
rs:WP_021462518	DNA topoisomerase III [Gallibacterium anatis].	33.63	556	338	13	8	548	5	544	1e-88	301
rs:WP_039092466	DNA topoisomerase III [Gallibacterium anatis].	33.99	556	336	14	8	548	5	544	1e-88	300
rs:WP_014338762	DNA topoisomerase III [Pseudomonas fluorescens].	34.79	549	325	13	8	539	5	537	1e-88	300
rs:WP_034691397	DNA topoisomerase III [Acidovorax sp. MR-S7].	33.63	559	343	11	8	552	5	549	1e-88	300
rs:WP_041668451	DNA topoisomerase III, partial [Ralstonia pickettii].	33.45	568	341	14	4	552	1	550	1e-88	297
rs:WP_023381104	DNA topoisomerase III [Pseudomonas sp. VLB120].	34.64	560	330	14	7	548	4	545	1e-88	300
rs:WP_047351293	DNA topoisomerase III [Diaphorobacter sp. J5-51].	33.04	563	341	12	8	552	5	549	1e-88	300
rs:WP_039085585	DNA topoisomerase III [Gallibacterium anatis].	33.99	556	336	14	8	548	5	544	1e-88	300
rs:WP_043300054	DNA topoisomerase III [Burkholderia sp. TSV202].	34.04	567	332	15	8	552	5	551	1e-88	300
rs:WP_024718102	DNA topoisomerase III [Pseudomonas putida].	33.21	560	342	12	8	549	5	550	1e-88	300
rs:WP_027907079	DNA topoisomerase III [Pseudomonas taiwanensis].	34.64	560	330	14	7	548	4	545	1e-88	300
rs:WP_023112340	MULTISPECIES: hypothetical protein [Pseudomonas].	33.75	563	337	13	8	552	5	549	2e-88	300
rs:WP_016190694	DNA topoisomerase III [Erwinia tracheiphila].	35.50	538	320	11	8	531	5	529	2e-88	300
rs:WP_021205167	DNA topoisomerase III [Pseudomonas aeruginosa].	33.57	563	338	13	8	552	5	549	2e-88	300
rs:WP_022579834	DNA topoisomerase III [Pseudomonas aeruginosa].	34.46	563	333	13	8	552	5	549	2e-88	300
rs:WP_042773587	hypothetical protein, partial [Salmonella enterica].	33.00	600	370	14	1	582	1	586	2e-88	299
rs:WP_033991652	DNA topoisomerase III [Pseudomonas aeruginosa].	34.64	563	332	13	8	552	5	549	2e-88	300
rs:WP_031204974	DNA topoisomerase III, partial [Gallibacterium anatis].	33.16	561	345	12	8	553	5	550	2e-88	298
rs:WP_020230133	DNA topoisomerase III [Acidovorax sp. MR-S7].	33.63	559	343	11	8	552	30	574	2e-88	300
rs:WP_043294193	DNA topoisomerase III [Burkholderia pseudomallei].	33.22	566	339	13	8	552	5	552	2e-88	300
rs:WP_046482630	DNA topoisomerase III [Pseudomonas veronii].	33.57	563	338	12	8	552	5	549	3e-88	299
rs:WP_020651207	DNA topoisomerase III [Solimonas variicoloris].	33.63	568	340	14	4	552	1	550	3e-88	300
rs:WP_004566591	dna topoisomerase ec=5.99.1.2 [Bordetella bronchiseptica].	33.57	563	338	13	8	552	5	549	3e-88	299
rs:WP_034017561	DNA topoisomerase III [Pseudomonas aeruginosa].	34.46	563	333	13	8	552	5	549	3e-88	299
rs:WP_039594020	DNA topoisomerase III [Pseudomonas frederiksbergensis].	33.39	560	341	12	8	549	5	550	3e-88	299
rs:WP_021462028	DNA topoisomerase III [Gallibacterium anatis].	33.16	561	345	12	8	553	5	550	3e-88	298
rs:WP_015062325	DNA topoisomerase III [Salmonella sp. 40].	33.00	600	370	14	1	582	1	586	4e-88	299
tr:V1FMZ2_SALCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.00	600	370	14	1	582	1	586	4e-88	299
rs:WP_034065554	DNA topoisomerase III [Pseudomonas aeruginosa].	32.80	567	341	12	8	552	5	553	4e-88	299
rs:WP_039576863	DNA topoisomerase III [Pseudomonas parafulva].	33.27	565	340	12	7	548	4	554	5e-88	299
rs:WP_039136943	DNA topoisomerase III, partial [Gallibacterium genomosp. 2].	33.09	559	336	12	5	544	3	542	5e-88	297
rs:WP_008092883	DNA topoisomerase III, partial [Pseudomonas sp. GM84].	33.93	560	334	13	7	548	4	545	5e-88	298
rs:WP_039588664	DNA topoisomerase III [Pseudomonas frederiksbergensis].	35.45	550	319	14	8	539	5	536	6e-88	298
rs:WP_025809837	DNA topoisomerase III [Pseudomonas chlororaphis].	33.75	566	336	14	8	552	5	552	7e-88	298
rs:WP_045969710	DNA topoisomerase III [Xenorhabdus doucetiae].	34.61	549	329	11	8	539	5	540	8e-88	298
rs:WP_027899045	DNA topoisomerase III [Pseudomonas syringae].	32.50	560	345	13	8	550	5	548	8e-88	298
rs:WP_016392731	DNA topoisomerase III [Pseudomonas plecoglossicida].	33.93	560	334	14	7	548	4	545	9e-88	298
rs:WP_036586587	DNA topoisomerase III [Ochrobactrum anthropi].	33.39	563	335	15	8	548	5	549	1e-87	298
rs:WP_025920348	DNA topoisomerase III [Pectobacterium wasabiae].	32.56	559	349	10	8	552	5	549	1e-87	298
rs:WP_003158613	DNA topoisomerase III [Pseudomonas aeruginosa].	33.51	567	337	12	8	552	5	553	1e-87	298
rs:WP_038201453	DNA topoisomerase III [Xenophilus azovorans].	33.39	566	342	11	8	552	5	556	1e-87	298
rs:WP_012824474	DNA topoisomerase III [Halothiobacillus neapolitanus].	33.98	565	332	16	8	553	5	547	1e-87	298
rs:WP_027919719	DNA topoisomerase III [Pseudomonas sp. URMO17WK12:I8].	34.11	560	333	14	7	548	4	545	1e-87	297
tr:A0A068QQ25_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.61	549	329	11	8	539	11	546	1e-87	298
rs:WP_040031775	DNA topoisomerase III [Pectobacterium carotovorum].	32.20	559	351	10	8	552	5	549	1e-87	298
rs:WP_041021229	DNA topoisomerase III [Pseudomonas sp. SHC52].	34.47	557	315	14	8	539	5	536	1e-87	297
rs:WP_004534801	DNA topoisomerase III [Burkholderia pseudomallei].	33.22	566	339	12	8	552	5	552	1e-87	298
rs:WP_034079732	DNA topoisomerase III [Pseudomonas aeruginosa].	34.10	563	335	12	8	552	5	549	2e-87	297
rs:WP_011347592	DNA topoisomerase III [Xanthomonas euvesicatoria].	33.75	563	337	13	8	552	5	549	2e-87	297
rs:WP_032963652	DNA topoisomerase III [Bordetella hinzii].	34.04	564	335	14	8	552	5	550	2e-87	297
rs:WP_039607059	DNA topoisomerase III, partial [Pseudomonas tuomuerensis].	33.10	568	337	14	8	552	5	552	2e-87	296
rs:WP_023102544	hypothetical protein [Pseudomonas aeruginosa].	33.27	565	340	12	8	552	5	552	2e-87	297
rs:WP_008930006	DNA topoisomerase III [Alcanivorax hongdengensis].	32.97	555	345	11	8	549	5	545	2e-87	297
rs:WP_029615659	DNA topoisomerase III [Pseudomonas putida].	33.93	560	334	14	7	548	4	545	2e-87	296
rs:WP_033448876	MULTISPECIES: DNA topoisomerase III [Alcaligenaceae].	33.75	563	337	13	8	552	5	549	2e-87	297
rs:WP_034032947	DNA topoisomerase III [Pseudomonas aeruginosa].	33.93	563	336	13	8	552	5	549	2e-87	297
rs:WP_031635081	DNA topoisomerase III [Pseudomonas aeruginosa].	33.10	568	343	14	4	552	1	550	2e-87	297
rs:WP_014590367	DNA topoisomerase III [Pseudomonas putida].	33.45	556	342	12	7	548	4	545	2e-87	296
rs:WP_041908197	DNA topoisomerase III [Enterobacter sp. BIDMC 29].	34.94	538	323	11	8	531	5	529	2e-87	297
rs:WP_039325610	DNA topoisomerase III [Pectobacterium betavasculorum].	33.09	559	346	12	8	552	5	549	2e-87	297
rs:WP_021441660	DNA topoisomerase III [Pseudomonas sp. EGD-AK9].	33.69	564	337	14	8	552	5	550	2e-87	297
rs:WP_042176628	DNA topoisomerase III [Pseudomonas aeruginosa].	33.51	567	337	12	8	552	5	553	2e-87	297
rs:WP_044202797	DNA topoisomerase III [Pectobacterium carotovorum].	32.56	559	349	11	8	552	5	549	3e-87	297
rs:WP_033947985	DNA topoisomerase III [Pseudomonas aeruginosa].	33.57	563	338	13	8	552	5	549	3e-87	297
rs:WP_038397646	DNA topoisomerase III [Salmonella enterica].	33.03	554	341	12	8	546	5	543	3e-87	297
rs:WP_033472286	DNA topoisomerase III [Bordetella bronchiseptica].	33.75	563	337	13	8	552	5	549	3e-87	297
rs:WP_021179591	DNA topoisomerase III [Serratia fonticola].	34.58	561	332	15	7	549	4	547	3e-87	296
rs:WP_009876577	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	32.51	566	343	12	8	552	5	552	3e-87	297
rs:WP_010954821	DNA topoisomerase III [Pseudomonas putida].	33.81	556	340	13	7	548	4	545	3e-87	296
rs:WP_029613131	DNA topoisomerase III [Pseudomonas sp. ICMP 17674].	33.80	571	331	15	7	548	4	556	3e-87	296
rs:WP_042583917	DNA topoisomerase III [Burkholderia sp. MSHR3999].	33.22	566	339	13	8	552	5	552	3e-87	297
rs:WP_011609880	DNA topoisomerase III [Histophilus somni].	33.27	559	344	12	8	552	5	548	3e-87	297
rs:WP_028613339	DNA topoisomerase III [Pseudomonas putida].	33.75	560	335	14	7	548	4	545	3e-87	296
rs:WP_005966930	MULTISPECIES: DNA topoisomerase III [Pectobacterium].	32.74	559	348	11	8	552	5	549	4e-87	296
rs:WP_038612001	DNA topoisomerase III [Pseudomonas alkylphenolia].	33.33	564	336	13	8	549	5	550	4e-87	296
rs:WP_024910502	DNA topoisomerase III [Serratia fonticola].	33.45	559	341	12	7	549	4	547	4e-87	296
rs:WP_008265951	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	33.93	563	336	12	8	552	5	549	4e-87	296
rs:WP_023095522	hypothetical protein [Pseudomonas aeruginosa].	33.93	563	336	13	8	552	5	549	4e-87	296
rs:WP_033990595	DNA topoisomerase III [Pseudomonas aeruginosa].	33.93	563	336	12	8	552	5	549	4e-87	296
rs:WP_036987227	DNA topoisomerase III, partial [Pseudomonas mendocina].	33.92	566	333	15	8	552	5	550	5e-87	293
rs:WP_044314042	DNA topoisomerase III [Pseudomonas stutzeri].	34.10	563	335	12	8	552	5	549	5e-87	296
rs:WP_005793094	DNA topoisomerase III [Acidovorax delafieldii].	33.57	563	338	13	8	552	5	549	5e-87	296
rs:WP_034103292	DNA topoisomerase III [Pseudomonas fluorescens].	34.11	557	317	14	8	539	5	536	5e-87	296
rs:WP_039551814	DNA topoisomerase III [Pectobacterium carotovorum].	32.74	559	348	11	8	552	5	549	6e-87	296
tr:H1BTD4_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.04	560	342	11	8	549	5	549	6e-87	296
rs:WP_027592745	DNA topoisomerase III [Pseudomonas sp. LAIL14HWK12:I7].	33.93	560	334	14	7	548	4	545	6e-87	295
rs:WP_029484957	DNA topoisomerase III [Enterobacter mori].	33.39	569	334	14	8	552	5	552	6e-87	296
rs:WP_012051818	DNA topoisomerase III [Pseudomonas putida].	33.27	556	343	12	7	548	4	545	7e-87	295
rs:WP_034030437	DNA topoisomerase III [Pseudomonas aeruginosa].	33.57	563	338	13	8	552	5	549	7e-87	296
rs:WP_028622299	DNA topoisomerase III [Pseudomonas sp. Ant30-3].	32.92	568	339	14	8	552	5	553	7e-87	296
rs:WP_031764334	DNA topoisomerase III [Pseudomonas aeruginosa].	33.22	569	338	14	8	552	5	555	7e-87	296
rs:WP_011804749	DNA topoisomerase III [Acidovorax sp. JS42].	33.04	563	341	12	8	552	5	549	7e-87	296
rs:WP_011633249	DNA topoisomerase III [Nitrosomonas eutropha].	34.22	561	332	13	8	549	5	547	7e-87	296
rs:WP_039694986	DNA topoisomerase III [Dickeya solani].	34.04	564	335	14	8	552	5	550	8e-87	295
rs:WP_009408843	DNA topoisomerase III [Pseudomonas putida].	34.17	559	332	14	8	548	5	545	8e-87	295
rs:WP_047039718	DNA topoisomerase III [Enterobacter aerogenes].	34.31	545	329	11	8	539	5	533	8e-87	293
rs:WP_026031846	DNA topoisomerase III [Pseudomonas putida].	33.27	556	343	12	7	548	4	545	9e-87	295
rs:WP_001177801	DNA topoisomerase III [Escherichia coli].	33.04	560	342	11	8	549	5	549	1e-86	295
rs:WP_042920648	DNA topoisomerase III [Pseudomonas chloritidismutans].	33.57	563	338	13	8	552	5	549	1e-86	295
rs:WP_016488133	DNA topoisomerase III [Pseudomonas putida].	33.75	560	335	14	7	548	4	545	1e-86	295
rs:WP_038995774	DNA topoisomerase III [Pseudomonas putida].	34.46	560	331	14	7	548	4	545	1e-86	294
rs:WP_011804699	DNA topoisomerase III [Acidovorax sp. JS42].	33.04	563	341	12	8	552	5	549	1e-86	295
rs:WP_029290885	DNA topoisomerase III [Pseudomonas fluorescens].	34.47	557	315	14	8	539	5	536	1e-86	295
rs:WP_037404599	DNA topoisomerase III [Serratia sp. Ag2].	33.16	561	339	13	8	552	5	545	1e-86	295
rs:WP_034044103	DNA topoisomerase III [Pseudomonas aeruginosa].	33.22	569	338	14	8	552	5	555	1e-86	295
rs:WP_040230287	DNA topoisomerase III [Citrobacter sp. CIP 55.13].	33.82	544	333	10	8	539	5	533	2e-86	293
rs:WP_013973300	MULTISPECIES: DNA topoisomerase III [Pseudomonas putida group].	33.27	556	343	13	7	548	4	545	2e-86	294
rs:WP_003098974	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	33.22	569	338	14	8	552	5	555	2e-86	295
rs:WP_013721964	DNA topoisomerase III [Alicycliphilus denitrificans].	33.10	568	343	14	4	552	1	550	2e-86	295
rs:WP_027015253	DNA topoisomerase III [Comamonas composti].	33.16	567	339	12	8	552	5	553	2e-86	295
tr:A0A0A8RP43_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.22	569	338	14	8	552	5	555	2e-86	295
rs:WP_014755959	DNA topoisomerase III [Pseudomonas putida].	33.27	556	343	12	7	548	4	545	2e-86	294
rs:WP_043143773	DNA topoisomerase III [Serratia marcescens].	31.79	604	373	14	8	590	5	590	2e-86	295
rs:WP_039503344	DNA topoisomerase III [Pectobacterium carotovorum].	32.74	559	348	11	8	552	5	549	2e-86	295
rs:WP_046803444	DNA topoisomerase III [Achromobacter sp. LC458].	32.16	566	345	12	8	552	5	552	2e-86	295
rs:WP_012564926	DNA topoisomerase III [Haemophilus influenzae].	32.92	562	344	13	7	552	4	548	2e-86	295
rs:WP_003116834	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	33.22	569	338	14	8	552	5	555	2e-86	295
rs:WP_043154374	DNA topoisomerase III [Pseudomonas aeruginosa].	33.57	563	338	13	8	552	5	549	2e-86	294
rs:WP_003108987	DNA topoisomerase III [Pseudomonas aeruginosa].	33.22	569	338	14	8	552	5	555	2e-86	294
rs:WP_046482944	DNA topoisomerase III [Pseudomonas veronii].	32.81	570	337	14	8	552	5	553	2e-86	294
rs:WP_040089341	DNA topoisomerase III [Escherichia coli].	33.21	560	341	11	8	549	5	549	2e-86	294
rs:WP_004115565	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	35.00	540	322	10	8	531	5	531	3e-86	294
rs:WP_020207115	DNA topoisomerase III [Cupriavidus sp. WS].	32.86	563	342	13	8	552	5	549	3e-86	294
rs:WP_038255203	DNA topoisomerase III [Xenorhabdus bovienii].	34.01	541	326	13	8	531	5	531	3e-86	294
rs:WP_012146809	DNA topoisomerase III [Serratia proteamaculans].	32.32	594	364	13	8	580	5	581	3e-86	294
rs:WP_034022471	DNA topoisomerase III [Pseudomonas aeruginosa].	33.04	569	339	14	8	552	5	555	3e-86	294
rs:WP_031652706	DNA topoisomerase III [Pseudomonas aeruginosa].	33.04	569	339	14	8	552	5	555	3e-86	294
rs:WP_033636010	DNA topoisomerase III [Serratia marcescens].	33.09	556	340	11	8	546	5	545	3e-86	294
rs:WP_040277052	DNA topoisomerase III [Xanthomonas citri].	32.50	563	344	12	8	552	5	549	3e-86	294
rs:WP_025513247	DNA topoisomerase III [Bordetella trematum].	33.27	568	342	14	4	552	1	550	3e-86	294
rs:WP_039498870	DNA topoisomerase III [Pectobacterium carotovorum].	32.56	559	349	11	8	552	5	549	3e-86	294
rs:WP_028690960	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	32.86	563	342	12	8	552	5	549	3e-86	294
rs:WP_032214913	DNA topoisomerase III, partial [Escherichia coli].	32.74	562	341	12	8	549	5	549	3e-86	293
rs:WP_014853514	DNA topoisomerase III [Pseudomonas stutzeri].	33.45	559	336	13	8	548	5	545	4e-86	293
rs:WP_031688162	DNA topoisomerase III [Pseudomonas aeruginosa].	33.27	568	342	14	4	552	1	550	4e-86	294
rs:WP_005687564	DNA topoisomerase III [Haemophilus influenzae].	32.98	561	343	13	8	552	5	548	4e-86	294
rs:WP_037023194	DNA topoisomerase III [Pseudomonas sp. 20_BN].	32.61	555	346	11	8	548	5	545	4e-86	293
rs:WP_041025084	DNA topoisomerase III [Pseudomonas aeruginosa].	33.39	563	339	12	8	552	5	549	4e-86	293
rs:WP_014064994	DNA topoisomerase III [Haemophilus parainfluenzae].	32.80	561	344	13	8	552	5	548	4e-86	294
rs:WP_005667784	DNA topoisomerase III [Haemophilus influenzae].	32.80	561	344	13	8	552	5	548	4e-86	294
rs:WP_004538149	DNA topoisomerase III [Burkholderia pseudomallei].	33.80	568	333	14	8	552	5	552	4e-86	294
rs:WP_030132226	DNA topoisomerase III [Pseudomonas sp. QTF5].	33.39	563	339	12	8	552	5	549	5e-86	293
rs:WP_026383892	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	33.93	563	336	12	8	552	5	549	5e-86	293
rs:WP_010566039	DNA topoisomerase III [Pseudomonas extremaustralis].	34.40	564	324	15	8	548	5	545	5e-86	293
rs:WP_028699042	DNA topoisomerase III [Pseudomonas monteilii].	33.39	560	337	14	7	548	4	545	5e-86	293
rs:WP_004265528	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	33.10	568	343	13	4	552	1	550	5e-86	293
rs:WP_023098549	hypothetical protein [Pseudomonas aeruginosa].	33.22	569	338	14	8	552	5	555	6e-86	293
rs:WP_016418561	hypothetical protein [Halomonas anticariensis].	32.50	597	366	13	8	581	6	588	6e-86	293
rs:WP_010846407	DNA topoisomerase III [Xenorhabdus nematophila].	34.14	577	342	14	8	563	5	564	7e-86	293
rs:WP_043988817	DNA topoisomerase III [Pectobacterium wasabiae].	32.38	559	350	11	8	552	5	549	7e-86	293
rs:WP_033981900	DNA topoisomerase III [Pseudomonas aeruginosa].	33.39	563	339	12	8	552	5	549	7e-86	293
rs:WP_017640402	DNA topoisomerase III [Pseudomonas sp. 313].	33.21	563	340	13	8	552	5	549	8e-86	293
rs:WP_009461166	MULTISPECIES: DNA topoisomerase III [Alcaligenes].	32.92	568	344	14	4	552	1	550	8e-86	293
rs:WP_012639367	DNA topoisomerase III [Thioalkalivibrio sulfidiphilus].	33.21	560	345	12	8	552	5	550	8e-86	293
rs:WP_024671564	DNA topoisomerase III [Pseudomonas syringae].	32.80	561	340	13	8	549	5	547	8e-86	293
rs:WP_028447326	DNA topoisomerase III [Chitinimonas koreensis].	32.98	564	341	13	8	552	5	550	8e-86	293
rs:WP_026020317	DNA topoisomerase III [Pseudomonas putida].	33.39	560	337	14	7	548	4	545	8e-86	292
rs:WP_019844491	DNA topoisomerase III [Dickeya zeae].	33.21	563	340	13	8	552	5	549	9e-86	293
tr:A0A099E931_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.57	560	336	14	7	548	4	545	1e-85	292
rs:WP_043547201	DNA topoisomerase III [Pseudomonas aeruginosa].	33.27	568	342	14	4	552	1	550	1e-85	293
tr:D0KM86_PECWW	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.38	559	350	11	8	552	1	545	1e-85	292
rs:WP_021782144	MULTISPECIES: DNA topoisomerase III [Pseudomonas putida group].	33.09	556	344	12	7	548	4	545	1e-85	292
rs:WP_036994754	DNA topoisomerase III [Pseudomonas sp. P482].	34.35	559	331	14	8	548	5	545	1e-85	292
rs:WP_025753452	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	33.39	560	337	14	7	548	4	545	1e-85	292
rs:WP_039525738	DNA topoisomerase III [Pectobacterium carotovorum].	32.38	559	350	11	8	552	5	549	1e-85	293
rs:WP_027608787	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	33.39	560	337	14	7	548	4	545	1e-85	292
rs:WP_033699921	DNA topoisomerase III [Pseudomonas sp. WCS358].	33.57	560	336	14	7	548	4	545	1e-85	292
rs:WP_011533418	DNA topoisomerase III [Pseudomonas entomophila].	33.15	555	343	12	8	548	5	545	1e-85	292
rs:WP_016498844	DNA topoisomerase III [Pseudomonas putida].	33.27	556	343	12	7	548	4	545	1e-85	292
tr:A0A085IJE3_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.57	541	325	10	7	531	4	531	1e-85	291
rs:WP_017530498	DNA topoisomerase III [Pseudomonas fluorescens].	34.17	559	332	14	8	548	5	545	1e-85	292
rs:WP_006777725	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	35.00	540	322	10	8	531	5	531	1e-85	292
rs:WP_032958220	DNA topoisomerase III [Bordetella hinzii].	33.80	568	339	14	4	552	1	550	1e-85	292
rs:WP_004576972	DNA topoisomerase III [Pseudomonas putida].	33.09	556	344	12	7	548	4	545	1e-85	292
rs:WP_005653577	DNA topoisomerase III [Haemophilus influenzae].	32.74	562	345	13	7	552	4	548	1e-85	293
rs:WP_023106356	hypothetical protein [Pseudomonas aeruginosa].	32.04	568	345	12	8	552	5	554	1e-85	292
rs:WP_040975693	DNA topoisomerase III [Pasteurella sp. FF6].	32.80	561	344	13	8	552	5	548	1e-85	293
rs:WP_033955185	DNA topoisomerase III [Pseudomonas aeruginosa].	33.22	569	338	14	8	552	5	555	1e-85	292
rs:WP_039613170	DNA topoisomerase III [Pseudomonas sp. C5pp].	33.45	556	342	12	7	548	4	545	1e-85	291
rs:WP_023103931	hypothetical protein [Pseudomonas aeruginosa].	32.68	563	343	12	8	552	5	549	1e-85	292
rs:WP_046337374	DNA topoisomerase III [Xenorhabdus bovienii].	34.00	550	328	12	8	539	5	537	1e-85	292
rs:WP_017513937	hypothetical protein, partial [beta proteobacterium FWI2].	33.27	541	327	12	8	530	5	529	1e-85	288
rs:WP_035921612	hypothetical protein, partial [Legionella moravica].	32.53	581	348	18	8	563	5	566	2e-85	291
rs:WP_034058298	DNA topoisomerase III [Pseudomonas aeruginosa].	33.22	575	331	16	8	552	5	556	2e-85	292
rs:WP_032608280	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	34.63	540	324	10	8	531	5	531	2e-85	292
rs:WP_003251239	DNA topoisomerase III [Pseudomonas putida].	33.09	556	344	12	7	548	4	545	2e-85	291
rs:WP_010223989	DNA topoisomerase III [Pseudomonas sp. HYS].	34.35	559	331	14	8	548	5	545	2e-85	291
rs:WP_025339781	DNA topoisomerase III [Pseudomonas sp. FGI182].	33.09	556	344	12	7	548	4	545	2e-85	291
rs:WP_010792172	DNA topoisomerase III [Pseudomonas aeruginosa].	33.10	568	343	14	4	552	1	550	2e-85	292
rs:WP_043082055	DNA topoisomerase III [Pluralibacter gergoviae].	34.63	540	324	10	8	531	5	531	2e-85	292
rs:WP_045816928	DNA topoisomerase III [Pantoea sp. SM3].	34.11	557	336	12	8	548	5	546	2e-85	292
rs:WP_012768236	MULTISPECIES: DNA topoisomerase III [Dickeya].	32.68	563	343	12	8	552	5	549	2e-85	292
rs:WP_046614845	DNA topoisomerase III [Pseudomonas putida].	33.09	556	344	12	7	548	4	545	2e-85	291
rs:WP_024537139	DNA topoisomerase III [Comamonas badia].	33.27	568	342	14	4	552	1	550	2e-85	292
rs:WP_034037691	DNA topoisomerase III [Pseudomonas aeruginosa].	33.27	568	342	14	4	552	1	550	2e-85	292
rs:WP_001401071	DNA topoisomerase III family protein [Escherichia coli].	32.86	560	343	11	8	549	5	549	2e-85	291
rs:WP_003036629	DNA topoisomerase III [Citrobacter freundii].	34.81	540	323	10	8	531	5	531	2e-85	292
rs:WP_039264698	DNA topoisomerase III [Enterobacter cloacae].	34.63	540	324	10	8	531	5	531	2e-85	291
rs:WP_003821061	MULTISPECIES: dna topoisomerase ec=5.99.1.2 [Proteobacteria].	33.21	563	340	13	8	552	5	549	2e-85	292
rs:WP_038220810	DNA topoisomerase III [Xenorhabdus nematophila].	33.45	550	338	12	8	543	5	540	2e-85	291
rs:WP_023124357	hypothetical protein [Pseudomonas aeruginosa].	33.27	568	342	14	4	552	1	550	2e-85	291
rs:WP_016807975	DNA topoisomerase III [Klebsiella oxytoca].	34.63	540	324	10	8	531	5	531	2e-85	291
rs:WP_003283902	DNA topoisomerase III [Pseudomonas stutzeri].	33.04	560	338	13	8	548	5	546	2e-85	291
rs:WP_024483847	DNA topoisomerase III [Serratia fonticola].	34.05	561	335	15	7	549	4	547	2e-85	291
rs:WP_001720566	DNA topoisomerase III family protein [Escherichia coli].	32.86	560	343	11	8	549	5	549	3e-85	291
rs:WP_009114262	DNA topoisomerase III [Brenneria sp. EniD312].	31.73	602	374	14	8	590	5	588	3e-85	291
rs:WP_038625712	DNA topoisomerase III [Pantoea sp. PSNIH2].	32.92	568	344	13	4	552	1	550	3e-85	291
rs:WP_040118093	DNA topoisomerase III [Enterobacter cloacae].	34.63	540	324	10	8	531	5	531	3e-85	291
rs:WP_004663540	DNA topoisomerase III [Pseudomonas savastanoi].	32.62	561	341	13	8	549	5	547	3e-85	291
rs:WP_033648773	DNA topoisomerase III [Serratia marcescens].	32.91	556	341	11	8	546	5	545	3e-85	291
rs:WP_015270975	DNA topoisomerase III [Pseudomonas putida].	33.39	560	337	14	7	548	4	545	3e-85	291
rs:WP_023205275	DNA topoisomerase III [Salmonella enterica].	35.00	540	322	10	8	531	5	531	4e-85	291
rs:WP_042998113	DNA topoisomerase III [Citrobacter sp. MGH 55].	34.63	540	324	10	8	531	5	531	4e-85	291
rs:WP_011489283	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	32.33	563	345	12	8	552	5	549	4e-85	291
rs:WP_033948794	DNA topoisomerase III [Pseudomonas aeruginosa].	32.86	563	342	12	8	552	5	549	4e-85	291
rs:WP_014159680	DNA topoisomerase III [Pseudoxanthomonas spadix].	32.62	564	344	13	7	552	4	549	4e-85	291
rs:WP_032886647	DNA topoisomerase III [Pseudomonas sp. RIT357].	34.40	564	324	15	8	548	5	545	4e-85	290
rs:WP_046857838	DNA topoisomerase III [Pseudomonas sp. CCOS191].	33.81	559	334	14	8	548	5	545	4e-85	290
rs:WP_045282284	DNA topoisomerase III [Enterobacter sp. 44593].	34.44	540	325	10	8	531	5	531	4e-85	291
rs:WP_018988644	DNA topoisomerase III [Azoarcus toluclasticus].	33.33	564	339	14	8	552	5	550	4e-85	291
rs:WP_041013292	DNA topoisomerase III [Pseudomonas xanthomarina].	33.21	560	337	14	8	548	5	546	4e-85	290
rs:WP_031594540	DNA topoisomerase III [Pantoea agglomerans].	34.57	541	325	10	7	531	4	531	4e-85	291
rs:WP_043743360	DNA topoisomerase III [Thauera sp. SWB20].	32.92	568	344	13	4	552	1	550	4e-85	291
rs:WP_017904483	DNA topoisomerase III [Pseudomonas fuscovaginae].	33.27	556	343	12	7	548	4	545	4e-85	290
rs:WP_033992584	DNA topoisomerase III [Pseudomonas aeruginosa].	33.04	569	339	14	8	552	5	555	4e-85	291
rs:WP_034065220	DNA topoisomerase III [Pseudomonas aeruginosa].	32.68	563	343	12	8	552	5	549	4e-85	291
rs:WP_023657257	DNA topoisomerase III [Pseudomonas aeruginosa].	32.68	563	343	12	8	552	5	549	5e-85	291
rs:WP_042927335	DNA topoisomerase III [Pseudomonas chloritidismutans].	32.62	564	343	14	8	552	5	550	5e-85	291
rs:WP_013811158	MULTISPECIES: DNA topoisomerase III [Serratia].	32.15	594	365	13	8	580	5	581	5e-85	291
rs:WP_021264249	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	33.39	563	339	13	8	552	5	549	5e-85	291
rs:WP_023285893	hypothetical protein [Klebsiella pneumoniae].	33.57	557	339	12	8	548	5	546	5e-85	291
rs:WP_009459717	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	32.50	563	344	13	8	552	5	549	5e-85	291
rs:WP_040031623	DNA topoisomerase III [Pectobacterium carotovorum].	32.02	559	352	10	8	552	5	549	5e-85	291
rs:WP_038409959	MULTISPECIES: DNA topoisomerase III [Pseudomonas putida group].	32.91	556	345	12	7	548	4	545	5e-85	290
rs:WP_038203143	DNA topoisomerase III [Xenorhabdus bovienii].	33.39	545	337	10	8	539	5	536	5e-85	290
rs:WP_008733910	DNA topoisomerase III [Alcanivorax pacificus].	33.21	560	345	12	8	552	5	550	5e-85	291
rs:WP_023534787	DNA topoisomerase III [Pseudomonas putida].	33.21	560	338	14	7	548	4	545	5e-85	290
rs:WP_044269281	DNA topoisomerase III [Pseudomonas fluorescens].	33.93	557	318	14	8	539	5	536	6e-85	290
rs:WP_007901001	DNA topoisomerase III [Pseudomonas sp. GM102].	34.29	557	316	14	8	539	5	536	6e-85	290
rs:WP_042997240	DNA topoisomerase III, partial [Bordetella bronchiseptica].	33.75	563	337	13	8	552	5	549	6e-85	290
rs:WP_038991132	DNA topoisomerase III [Klebsiella pneumoniae].	34.63	540	324	10	8	531	5	531	6e-85	290
rs:WP_023657732	DNA topoisomerase III [Pseudomonas aeruginosa].	33.10	568	343	14	4	552	1	550	6e-85	290
rs:WP_038705838	DNA topoisomerase III [Pseudomonas mosselii].	33.75	560	335	14	7	548	4	545	6e-85	290
rs:WP_017513957	DNA topoisomerase III, partial [beta proteobacterium FWI2].	32.54	544	330	11	8	530	5	532	7e-85	286
rs:WP_038925525	DNA topoisomerase III [Dickeya zeae].	32.15	619	377	16	7	603	4	601	7e-85	290
rs:WP_032972638	DNA topoisomerase III [Bordetella hinzii].	32.92	568	344	14	4	552	1	550	7e-85	290
rs:WP_014326561	DNA topoisomerase III [Haemophilus influenzae].	32.62	561	345	13	8	552	5	548	7e-85	290
rs:WP_012273226	DNA topoisomerase III [Pseudomonas putida].	33.21	560	338	14	7	548	4	545	8e-85	290
rs:WP_020300890	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	33.75	557	319	14	8	539	5	536	8e-85	290
rs:WP_033972349	DNA topoisomerase III [Pseudomonas aeruginosa].	32.15	563	346	12	8	552	5	549	8e-85	290
rs:WP_021248574	DNA topoisomerase III [Thauera terpenica].	33.87	564	336	14	8	552	5	550	8e-85	290
rs:WP_001177802	DNA topoisomerase III [Escherichia coli].	32.86	560	343	11	8	549	5	549	8e-85	290
rs:WP_031755005	DNA topoisomerase III [Pseudomonas aeruginosa].	33.10	568	343	14	4	552	1	550	8e-85	290
rs:WP_042094135	DNA topoisomerase III [Escherichia coli].	33.04	563	338	12	8	549	5	549	8e-85	290
rs:WP_043305647	DNA topoisomerase III [Pseudomonas viridiflava].	34.88	559	328	15	8	548	5	545	8e-85	290
tr:Q4QPE8_HAEI8	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.62	561	345	13	8	552	10	553	8e-85	290
rs:WP_037040786	DNA topoisomerase III [Pseudomonas sp. BAY1663].	33.10	568	343	14	4	552	1	550	9e-85	290
rs:WP_012004777	DNA topoisomerase III [Serratia proteamaculans].	32.15	594	365	13	8	580	5	581	9e-85	290
rs:WP_024008203	DNA topoisomerase III [Pseudomonas aeruginosa].	32.15	563	346	12	8	552	5	549	9e-85	290
rs:WP_032636758	DNA topoisomerase III [Enterobacter sp. MGH 15].	34.63	540	324	10	8	531	5	531	9e-85	290
rs:WP_013199786	DNA topoisomerase III [Erwinia billingiae].	33.15	558	342	12	8	549	5	547	9e-85	290
rs:WP_015038895	DNA topoisomerase III [Bordetella parapertussis].	32.57	568	346	14	4	552	1	550	1e-84	290
rs:WP_047296704	DNA topoisomerase III [Pseudomonas fluorescens].	33.82	550	328	14	8	539	5	536	1e-84	290
rs:WP_033947838	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	33.22	566	337	15	8	552	5	550	1e-84	290
rs:WP_047012732	DNA topoisomerase III [Spongiibacter sp. IMCC21906].	33.75	557	340	11	8	549	5	547	1e-84	290
rs:WP_024889541	DNA topoisomerase III [Luteimonas huabeiensis].	32.62	564	343	14	8	552	5	550	1e-84	290
rs:WP_033840334	DNA topoisomerase III [Bordetella bronchiseptica].	33.75	563	337	13	8	552	5	549	1e-84	290
tr:U3U493_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	35.06	542	321	11	7	531	4	531	1e-84	290
rs:WP_038216568	DNA topoisomerase III [Xenorhabdus bovienii].	33.58	545	336	10	8	539	5	536	1e-84	290
rs:WP_043212213	DNA topoisomerase III [Pseudomonas putida].	34.46	560	330	16	7	548	4	544	1e-84	289
rs:WP_001177799	DNA topoisomerase III [Escherichia coli].	32.86	560	343	11	8	549	5	549	1e-84	290
rs:WP_000765276	DNA topoisomerase III [Salmonella enterica].	33.04	560	333	14	8	546	5	543	1e-84	290
rs:WP_013982117	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	32.57	568	346	14	4	552	1	550	1e-84	290
rs:WP_040535462	hypothetical protein, partial [Legionella drancourtii].	32.86	563	335	15	8	548	5	546	2e-84	289
rs:WP_029593103	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	34.63	540	324	10	8	531	5	531	2e-84	289
rs:WP_001422194	DNA topoisomerase III family protein [Escherichia coli].	32.68	560	344	11	8	549	5	549	2e-84	289
rs:WP_009401127	DNA topoisomerase III [Pseudomonas putida].	33.10	568	343	14	4	552	1	550	2e-84	289
rs:WP_033555858	DNA topoisomerase III [Escherichia coli].	32.86	560	343	11	8	549	5	549	2e-84	289
rs:WP_036768648	DNA topoisomerase III [Photorhabdus asymbiotica].	33.57	560	337	14	8	548	5	548	2e-84	290
rs:WP_007885442	DNA topoisomerase III [Pantoea sp. GM01].	33.75	557	338	12	8	548	5	546	2e-84	290
rs:WP_001428196	DNA topoisomerase III family protein [Escherichia coli].	32.86	560	343	11	8	549	5	549	2e-84	289
rs:WP_034006787	DNA topoisomerase III [Pseudomonas aeruginosa].	32.15	563	346	12	8	552	5	549	2e-84	289
rs:WP_043199457	DNA topoisomerase III [Pseudomonas putida].	33.27	556	343	12	7	548	4	545	2e-84	289
rs:WP_046816037	DNA topoisomerase III [Pseudomonas putida].	34.18	550	326	14	8	539	5	536	2e-84	289
rs:WP_034148898	DNA topoisomerase III [Pseudomonas fluorescens].	33.81	559	334	13	8	548	5	545	2e-84	288
rs:WP_015056502	DNA topoisomerase III [Erwinia amylovora].	32.80	558	344	11	8	549	5	547	2e-84	290
tr:A0A0C8Q0Q4_SALTI	SubName: Full=TopB_1 protein {ECO:0000313|EMBL:CET05391.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CET05391.1};	32.50	560	345	11	8	549	5	549	2e-84	289
rs:WP_032897514	DNA topoisomerase III [Pseudomonas sp. Eur1 9.41].	34.10	566	323	16	8	548	5	545	2e-84	288
rs:WP_047351009	DNA topoisomerase III [Diaphorobacter sp. J5-51].	33.51	564	338	14	8	552	5	550	2e-84	289
rs:WP_045060819	DNA topoisomerase III [Pseudomonas sp. ES3-33].	33.57	560	334	15	8	549	5	544	2e-84	288
rs:WP_033879165	DNA topoisomerase III [Escherichia coli].	32.68	560	344	11	8	549	5	549	2e-84	289
rs:WP_023101516	hypothetical protein [Pseudomonas aeruginosa].	32.62	564	343	14	8	552	5	550	2e-84	289
rs:WP_033474391	DNA topoisomerase III [Bordetella bronchiseptica].	33.57	563	338	13	8	552	5	549	3e-84	289
rs:WP_040241313	DNA topoisomerase III, partial [Xanthomonas citri].	31.94	573	345	12	7	552	4	558	3e-84	288
rs:WP_045969231	DNA topoisomerase III [Xenorhabdus doucetiae].	34.24	549	331	11	8	539	5	540	3e-84	289
rs:WP_022963028	DNA topoisomerase III [Pseudomonas pelagia].	34.10	566	332	16	8	552	5	550	3e-84	289
rs:WP_021555971	hypothetical protein [Escherichia coli].	32.86	560	343	11	8	549	5	549	3e-84	289
rs:WP_038903512	DNA topoisomerase III [Dickeya zeae].	32.15	619	377	16	7	603	4	601	3e-84	289
rs:WP_019689274	DNA topoisomerase III [Pseudomonas fluorescens].	32.27	564	342	13	8	549	5	550	3e-84	289
rs:WP_044273187	DNA topoisomerase III [Pseudomonas fluorescens].	33.92	566	324	16	8	548	5	545	3e-84	288
rs:WP_042815526	DNA topoisomerase III, partial [Xanthomonas citri].	31.94	573	345	12	7	552	4	558	3e-84	288
rs:WP_042342345	DNA topoisomerase III [Escherichia coli].	32.86	560	343	11	8	549	5	549	3e-84	288
tr:G9EQA5_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.86	563	335	15	8	548	5	546	3e-84	288
tr:A0A068QPA2_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	34.24	549	331	11	8	539	11	546	3e-84	289
rs:WP_031632015	DNA topoisomerase III [Pseudomonas aeruginosa].	32.39	568	347	14	4	552	1	550	3e-84	288
rs:WP_018878671	hypothetical protein, partial [Thioalkalivibrio sp. ALE28].	32.82	518	313	10	41	539	1	502	3e-84	290
rs:WP_042125997	DNA topoisomerase III [Pseudomonas japonica].	34.17	559	332	14	8	548	5	545	3e-84	288
rs:WP_016973531	DNA topoisomerase III [Pseudomonas tolaasii].	33.75	563	323	14	8	545	5	542	3e-84	288
rs:WP_038265548	DNA topoisomerase III [Xenorhabdus cabanillasii].	33.83	538	328	12	8	531	5	528	4e-84	288
rs:WP_034017287	DNA topoisomerase III [Pseudomonas aeruginosa].	32.68	563	343	12	8	552	5	549	4e-84	288
rs:WP_042868977	DNA topoisomerase III [Dickeya sp. NCPPB 569].	32.69	618	373	16	8	603	5	601	4e-84	288
rs:WP_031592267	DNA topoisomerase III [Pantoea agglomerans].	32.80	558	344	11	8	549	5	547	4e-84	289
rs:WP_044322389	DNA topoisomerase III [Pseudomonas amygdali].	32.26	561	343	12	8	549	5	547	4e-84	288
rs:WP_038256049	DNA topoisomerase III [Xenorhabdus bovienii].	34.14	577	342	14	8	563	5	564	4e-84	288
rs:WP_038194406	DNA topoisomerase III [Xenorhabdus bovienii].	34.14	577	342	14	8	563	5	564	4e-84	288
rs:WP_017941455	hypothetical protein, partial [Thioalkalivibrio sp. ALE6].	32.63	518	314	10	41	539	1	502	4e-84	289
rs:WP_001536202	DNA topoisomerase III family protein [Escherichia coli].	32.68	560	344	11	8	549	5	549	4e-84	288
rs:WP_028632332	DNA topoisomerase III [Pseudomonas parafulva].	33.57	560	336	15	7	548	4	545	4e-84	288
rs:WP_045183922	DNA topoisomerase III [Pseudomonas sp. 5].	34.35	559	331	14	8	548	5	545	4e-84	288
tr:A0A077PMV3_XENBV	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.14	577	342	14	8	563	9	568	4e-84	288
rs:WP_042926554	DNA topoisomerase III [Pseudomonas chloritidismutans].	33.57	560	335	12	8	548	5	546	5e-84	288
tr:V2N7C2_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.91	556	345	12	7	549	4	544	5e-84	287
rs:WP_026136771	DNA topoisomerase III [Pseudomonas sp. CBZ-4].	34.40	564	324	15	8	548	5	545	5e-84	288
rs:WP_026949894	DNA topoisomerase III [Alcanivorax sp. 43B_GOM-46m].	33.21	560	339	12	5	539	3	552	5e-84	289
rs:WP_023093469	hypothetical protein [Pseudomonas aeruginosa].	32.33	563	345	12	8	552	5	549	5e-84	288
rs:WP_028692401	DNA topoisomerase III [Pseudomonas mosselii].	33.15	555	343	11	8	548	5	545	5e-84	287
rs:WP_021580322	hypothetical protein [Escherichia coli].	32.86	560	343	11	8	549	5	549	5e-84	288
rs:WP_046336289	DNA topoisomerase III [Xenorhabdus bovienii].	33.39	545	337	10	8	539	5	536	6e-84	288
rs:WP_016151302	hypothetical protein [Citrobacter sp. KTE151].	34.20	541	327	10	7	531	4	531	6e-84	288
rs:WP_036989946	DNA topoisomerase III [Pseudomonas bauzanensis].	33.69	564	337	14	8	552	5	550	6e-84	288
rs:WP_046061998	DNA topoisomerase III [Pseudomonas kilonensis].	33.33	555	324	12	8	539	5	536	6e-84	287
rs:WP_023464545	DNA topoisomerase III [Pseudomonas aeruginosa].	33.04	560	346	12	8	552	5	550	6e-84	288
rs:WP_006410664	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	32.98	564	341	14	8	552	5	550	7e-84	288
rs:WP_041013371	DNA topoisomerase III [Pseudomonas xanthomarina].	34.15	571	332	15	7	552	4	555	7e-84	288
rs:WP_039804356	DNA topoisomerase III [Azotobacter chroococcum].	32.56	562	351	12	1	548	1	548	7e-84	287
rs:WP_019584476	hypothetical protein, partial [Thioalkalivibrio sp. ALE16].	32.63	518	314	10	41	539	1	502	9e-84	288
rs:WP_026083050	DNA topoisomerase III [Pseudomonas tolaasii].	34.04	564	326	15	8	548	5	545	9e-84	287
rs:WP_015463225	MULTISPECIES: DNA topoisomerase III [Xanthomonas].	31.94	573	345	12	7	552	4	558	1e-83	288
rs:WP_031597904	DNA topoisomerase III, partial [Pseudomonas savastanoi].	32.44	561	342	13	8	549	5	547	1e-83	285
rs:WP_033873175	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	32.62	564	343	13	8	552	5	550	1e-83	285
rs:WP_013060258	DNA topoisomerase III [Yersinia pestis].	32.73	556	342	11	8	546	5	545	1e-83	287
rs:WP_039313330	DNA topoisomerase III [Pectobacterium carotovorum].	33.58	545	329	12	7	531	4	535	1e-83	287
rs:WP_044292940	DNA topoisomerase III [Pseudomonas amygdali].	32.44	561	342	13	8	549	5	547	1e-83	287
rs:WP_033872262	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	32.62	564	343	13	8	552	5	550	1e-83	285
rs:WP_001241570	DNA topoisomerase III [Salmonella enterica].	32.91	556	345	12	7	549	4	544	1e-83	287
tr:A0A0B6X684_XENBV	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.39	545	337	10	8	539	14	545	1e-83	287
rs:WP_025389726	DNA topoisomerase III [Pseudomonas syringae].	32.68	563	343	13	8	552	5	549	1e-83	287
rs:WP_023101001	hypothetical protein [Pseudomonas aeruginosa].	32.39	565	348	12	8	552	5	555	1e-83	287
rs:WP_034021440	DNA topoisomerase III [Pseudomonas aeruginosa].	32.39	568	347	14	4	552	1	550	1e-83	287
rs:WP_016978867	DNA topoisomerase III [Pseudomonas fluorescens].	33.45	553	326	12	8	539	5	536	1e-83	286
rs:WP_018158381	hypothetical protein, partial [Thioalkalivibrio sp. ALE14].	32.30	514	321	9	41	539	1	502	1e-83	288
rs:WP_021117221	DNA topoisomerase III family protein [Haemophilus parasuis].	33.15	552	334	14	8	539	5	541	1e-83	287
rs:WP_018168697	hypothetical protein, partial [Thioalkalivibrio sp. ALMg9].	32.30	514	321	9	41	539	1	502	2e-83	288
rs:WP_024153970	DNA topoisomerase III [Salmonella enterica].	32.91	556	345	12	7	549	4	544	2e-83	287
rs:WP_043862902	DNA topoisomerase III [Pseudomonas putida].	32.50	563	344	12	8	552	5	549	2e-83	287
rs:WP_020798922	DNA topoisomerase III family protein [Pseudomonas sp. G5(2012)].	33.04	566	338	16	8	552	5	550	2e-83	287
rs:WP_046162109	DNA topoisomerase III [Pseudomonas sp. 10B238].	34.05	561	333	15	7	548	4	546	2e-83	286
tr:F3FGU8_PSESX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	34.41	555	336	12	8	548	5	545	2e-83	284
tr:A0A0A4GET4_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.45	559	336	14	8	548	5	545	2e-83	286
tr:A0A0A5N0V8_SERMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.32	594	364	13	8	580	5	581	2e-83	287
rs:WP_024689379	DNA topoisomerase III [Pseudomonas syringae].	34.35	559	331	14	8	548	5	545	2e-83	286
rs:WP_046483316	DNA topoisomerase III [Pseudomonas veronii].	34.22	564	325	15	8	548	5	545	2e-83	286
rs:WP_044209346	DNA topoisomerase III [Pectobacterium carotovorum].	33.64	544	328	12	8	531	5	535	2e-83	286
rs:WP_023240864	DNA topoisomerase III [Salmonella enterica].	32.91	556	345	12	7	549	4	544	2e-83	286
rs:WP_029133587	DNA topoisomerase III [Sedimenticola selenatireducens].	32.39	568	347	14	4	552	1	550	2e-83	286
rs:WP_031755045	DNA topoisomerase III [Pseudomonas aeruginosa].	33.80	571	337	16	8	557	5	555	2e-83	286
rs:WP_013983541	DNA topoisomerase III [Pseudomonas stutzeri].	32.91	556	344	11	8	548	5	546	2e-83	286
rs:WP_017244814	DNA topoisomerase III [Pseudomonas stutzeri].	32.39	568	347	14	4	552	1	550	2e-83	286
rs:WP_023434592	DNA topoisomerase III [Pseudomonas aeruginosa].	32.45	564	344	13	8	552	5	550	2e-83	286
rs:WP_034127261	DNA topoisomerase III [Pseudomonas fluorescens].	33.75	566	325	16	8	548	5	545	2e-83	286
rs:WP_026296468	DNA topoisomerase III, partial [Thioalkalivibrio sp. ALJ2].	32.82	518	313	11	41	539	1	502	2e-83	287
rs:WP_011237227	DNA topoisomerase III [Aromatoleum aromaticum].	32.98	564	341	13	8	552	5	550	2e-83	286
rs:WP_033986198	DNA topoisomerase III [Pseudomonas aeruginosa].	32.57	568	346	14	4	552	1	550	2e-83	286
rs:WP_019568985	hypothetical protein, partial [Thioalkalivibrio sp. ALMg13-2].	32.43	518	315	10	41	539	1	502	2e-83	287
rs:WP_024153900	DNA topoisomerase III [Salmonella enterica].	32.91	556	345	12	7	549	4	544	2e-83	286
rs:WP_038913061	DNA topoisomerase III [Dickeya zeae].	31.99	619	378	16	7	603	4	601	2e-83	286
rs:WP_024074508	DNA topoisomerase III [Pseudomonas sp. TKP].	34.04	564	326	15	8	548	5	545	3e-83	286
rs:WP_043104890	DNA topoisomerase III [Pseudomonas aeruginosa].	32.39	568	347	14	4	552	1	550	3e-83	286
rs:WP_007971786	DNA topoisomerase III [Pseudomonas sp. GM33].	33.22	566	342	14	1	548	1	548	3e-83	286
rs:WP_028686538	DNA topoisomerase III [Pseudomonas fulva].	32.55	556	347	12	7	548	4	545	3e-83	286
tr:M4GX47_PECCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.27	564	349	12	8	553	5	553	3e-83	286
rs:WP_005607796	MULTISPECIES: DNA topoisomerase III [Actinobacillus].	31.96	557	348	13	8	548	5	546	3e-83	286
rs:WP_023093157	hypothetical protein [Pseudomonas aeruginosa].	32.92	568	344	14	4	552	1	550	3e-83	286
rs:WP_047335925	DNA topoisomerase III [Pseudomonas fluorescens].	32.39	568	347	14	4	552	1	550	3e-83	286
rs:WP_034365963	DNA topoisomerase III [Delftia sp. 670].	32.39	568	347	13	4	552	1	550	3e-83	286
rs:WP_034135351	DNA topoisomerase III [Pseudomonas fluorescens].	33.75	566	325	15	8	548	5	545	3e-83	285
rs:WP_034050572	DNA topoisomerase III [Pseudomonas aeruginosa].	32.45	564	344	14	8	552	5	550	3e-83	286
rs:WP_045196653	DNA topoisomerase III [Pseudomonas sp. 2(2015)].	33.93	560	334	14	7	548	4	545	3e-83	285
rs:WP_003454892	DNA topoisomerase III [Pseudomonas aeruginosa].	32.52	572	345	13	4	552	1	554	3e-83	286
rs:WP_026140036	DNA topoisomerase III [Pseudomonas veronii].	33.99	559	333	14	8	548	5	545	3e-83	285
rs:WP_045429170	DNA topoisomerase III [Pseudomonas sp. MT-1].	34.22	561	332	15	7	548	4	546	3e-83	285
rs:WP_003294153	DNA topoisomerase III [Pseudomonas stutzeri].	32.22	568	348	14	4	552	1	550	3e-83	286
rs:WP_029243501	DNA topoisomerase III [Pseudomonas viridiflava].	34.17	559	332	14	8	548	5	545	3e-83	285
rs:WP_033986546	DNA topoisomerase III [Pseudomonas aeruginosa].	32.57	568	346	13	4	552	1	550	4e-83	286
tr:A0A0A1GLH5_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.22	561	332	15	7	548	5	547	4e-83	285
rs:WP_027916196	DNA topoisomerase III [Pseudomonas sp. URMO17WK12:I11].	32.55	556	347	12	7	548	4	545	4e-83	285
rs:WP_011829934	DNA topoisomerase III [Methylibium petroleiphilum].	32.57	568	346	14	4	552	1	550	4e-83	286
rs:WP_034097216	DNA topoisomerase III [Pseudomonas fluorescens].	33.63	559	335	14	8	548	5	545	4e-83	285
rs:WP_025988385	DNA topoisomerase III [Burkholderia pseudomallei].	32.68	563	340	13	8	549	5	549	4e-83	286
rs:WP_019405243	DNA topoisomerase III [Pseudomonas stutzeri].	33.75	560	334	14	8	548	5	546	4e-83	285
rs:WP_003173078	DNA topoisomerase III [Pseudomonas fluorescens].	33.63	559	335	14	8	548	5	545	4e-83	285
tr:A0A061JJ33_PSEST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.16	564	340	13	2	546	11	556	4e-83	285
rs:WP_004886535	DNA topoisomerase III [Pseudomonas viridiflava].	33.99	559	333	14	8	548	5	545	4e-83	285
rs:WP_028941765	DNA topoisomerase III [Pseudomonas vranovensis].	33.63	556	341	12	7	548	4	545	4e-83	285
rs:WP_020308035	DNA topoisomerase III [Pseudomonas stutzeri].	32.92	568	344	14	4	552	1	550	4e-83	285
rs:WP_044423294	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	32.44	561	342	13	8	549	5	547	5e-83	286
rs:WP_022997579	hypothetical protein [Alcanivorax sp. PN-3].	33.04	560	340	12	5	539	3	552	5e-83	286
rs:WP_023912248	DNA topoisomerase III [Pseudomonas aeruginosa].	32.57	568	346	14	4	552	1	550	5e-83	285
rs:WP_003432932	DNA topoisomerase III [Pseudomonas syringae].	35.06	559	327	14	8	548	5	545	5e-83	285
rs:WP_014821142	DNA topoisomerase III [Pseudomonas stutzeri].	33.21	560	337	13	8	548	5	546	5e-83	285
rs:WP_041755624	DNA topoisomerase III [Pseudomonas stutzeri].	32.91	556	344	11	8	548	5	546	5e-83	285
rs:WP_021206679	DNA topoisomerase III [Pseudomonas stutzeri].	33.69	561	335	15	7	548	4	546	6e-83	285
rs:WP_034112916	DNA topoisomerase III [Pseudomonas fluorescens].	33.63	559	335	14	8	548	5	545	6e-83	285
rs:WP_046037339	DNA topoisomerase III [Pseudomonas fluorescens].	33.75	566	339	14	1	548	1	548	6e-83	285
rs:WP_028241262	DNA topoisomerase III [Pseudomonas azotifigens].	33.27	559	337	14	8	548	5	545	6e-83	285
rs:WP_024661949	DNA topoisomerase III [Pseudomonas syringae].	34.88	559	328	14	8	548	5	545	6e-83	285
rs:WP_043221507	DNA topoisomerase III [Pseudomonas balearica].	32.57	568	346	14	4	552	1	550	6e-83	285
rs:WP_024695632	DNA topoisomerase III [Pseudomonas syringae].	34.35	559	331	14	8	548	5	545	6e-83	285
rs:WP_003190339	DNA topoisomerase III [Pseudomonas fluorescens].	33.92	566	324	16	8	548	5	545	6e-83	285
rs:WP_046984497	DNA topoisomerase III [Thermomonas brevis].	33.16	573	341	15	4	552	1	555	6e-83	285
rs:WP_011334398	DNA topoisomerase III [Pseudomonas fluorescens].	33.51	555	323	12	8	539	5	536	6e-83	285
rs:WP_019751272	DNA topoisomerase III [Pseudomonas putida].	32.57	568	346	14	4	552	1	550	7e-83	285
rs:WP_012822377	DNA topoisomerase III [Pectobacterium wasabiae].	32.33	563	349	12	8	553	5	552	7e-83	285
rs:WP_008046973	DNA topoisomerase III [Pseudomonas sp. GM74].	33.22	566	342	14	1	548	1	548	7e-83	285
rs:WP_003290179	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	32.50	563	344	12	8	552	5	549	7e-83	285
rs:WP_045786180	DNA topoisomerase III [Ralstonia mannitolilytica].	32.27	564	345	14	8	552	5	550	7e-83	285
rs:WP_033874957	DNA topoisomerase III [Pseudomonas aeruginosa].	32.62	564	343	13	8	552	5	550	7e-83	285
rs:WP_018076215	MULTISPECIES: DNA topoisomerase III [Proteobacteria].	32.45	564	344	14	8	552	5	550	7e-83	285
rs:WP_039512817	DNA topoisomerase III [Pectobacterium carotovorum].	33.76	545	328	12	7	531	4	535	8e-83	285
rs:WP_033959578	DNA topoisomerase III [Pseudomonas aeruginosa].	32.45	564	344	14	8	552	5	550	8e-83	285
rs:WP_009521553	DNA topoisomerase III [Ralstonia sp. PBA].	32.39	568	347	14	4	552	1	550	8e-83	285
rs:WP_020306649	DNA topoisomerase III [Pseudomonas syringae].	32.09	561	344	13	8	549	5	547	8e-83	285
rs:WP_023124708	hypothetical protein [Pseudomonas aeruginosa].	32.33	563	345	13	8	552	5	549	9e-83	285
rs:WP_043741058	DNA topoisomerase III [Thauera sp. SWB20].	32.45	564	344	14	8	552	5	550	9e-83	285
rs:WP_025993493	DNA topoisomerase III [Pseudomonas viridiflava].	34.53	559	330	15	8	548	5	545	9e-83	284
rs:WP_023135508	DNA topoisomerase III [Salmonella enterica].	32.67	551	344	11	7	543	4	541	9e-83	285
rs:WP_013519532	DNA topoisomerase III [Alicycliphilus denitrificans].	32.45	564	344	13	8	552	5	550	9e-83	285
tr:F3GEC0_PSESJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	34.70	559	329	14	8	548	5	545	1e-82	284
rs:WP_018948401	hypothetical protein, partial [Thioalkalivibrio sp. ALMg11].	32.43	518	315	10	41	539	1	502	1e-82	286
rs:WP_033063590	DNA topoisomerase III [Pseudomonas sp. GM48].	33.39	566	341	14	1	548	1	548	1e-82	284
rs:WP_032905030	DNA topoisomerase III [Pseudomonas sp. CF150].	33.57	566	326	16	8	548	5	545	1e-82	284
rs:WP_042554705	DNA topoisomerase III [Pseudomonas fulva].	33.63	559	335	15	8	548	5	545	1e-82	284
rs:WP_025809783	DNA topoisomerase III [Pseudomonas chlororaphis].	31.56	564	349	13	8	552	5	550	1e-82	285
rs:WP_018873968	MULTISPECIES: hypothetical protein [Thioalkalivibrio].	32.36	516	314	10	43	539	1	500	1e-82	285
rs:WP_012340838	MULTISPECIES: DNA topoisomerase III [Pasteurellaceae].	32.85	551	337	13	8	539	5	541	1e-82	285
tr:J2RM32_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.63	559	335	14	8	548	5	545	1e-82	284
tr:J2TJ40_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.39	566	341	14	1	548	1	548	1e-82	284
tr:J2UTB3_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.22	566	342	13	1	548	2	549	1e-82	284
rs:WP_028622141	DNA topoisomerase III [Pseudomonas sp. Ant30-3].	33.45	559	336	13	8	548	5	545	1e-82	284
rs:WP_011805445	DNA topoisomerase III [Acidovorax sp. JS42].	32.57	568	346	14	4	552	1	550	1e-82	285
tr:G5QPK6_SALRU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.73	556	346	12	7	549	4	544	1e-82	285
rs:WP_003435765	DNA topoisomerase III [Pseudomonas syringae].	32.44	561	342	13	8	549	5	547	1e-82	285
rs:WP_032660787	DNA topoisomerase III [Pseudomonas syringae].	34.88	559	328	14	8	548	5	545	1e-82	284
rs:WP_005740008	DNA topoisomerase III [Pseudomonas amygdali].	32.44	561	342	13	8	549	5	547	1e-82	285
rs:WP_024781366	DNA topoisomerase III [Pseudomonas corrugata].	33.09	559	338	13	8	548	5	545	1e-82	283
rs:WP_033036896	DNA topoisomerase III [Pseudomonas sp. GM102].	33.45	559	336	13	8	548	5	545	1e-82	284
rs:WP_024767679	DNA topoisomerase III [Pseudomonas nitroreducens].	33.21	563	335	15	8	549	5	547	1e-82	284
rs:WP_034137853	DNA topoisomerase III [Pseudomonas fluorescens].	33.45	559	336	14	8	548	5	545	1e-82	284
rs:WP_027909879	DNA topoisomerase III [Pseudomonas sp. URMO17WK12:I4].	33.93	560	334	14	7	548	4	545	1e-82	284
rs:WP_016977365	DNA topoisomerase III [Pseudomonas fluorescens].	33.87	564	327	15	8	548	5	545	1e-82	284
rs:WP_046481894	DNA topoisomerase III [Pseudomonas veronii].	33.93	557	318	16	8	539	5	536	1e-82	284
tr:L7HKF7_PSEFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.69	564	328	15	8	548	7	547	1e-82	284
rs:WP_004410753	DNA topoisomerase III [Pseudomonas syringae].	34.35	559	331	14	8	548	5	545	1e-82	284
rs:WP_032832845	DNA topoisomerase III [Pseudomonas sp. GM67].	33.63	559	335	14	8	548	5	545	1e-82	283
rs:WP_017245828	DNA topoisomerase III [Pseudomonas stutzeri].	33.21	560	337	13	8	548	5	546	1e-82	283
rs:WP_003235825	DNA topoisomerase III [Pseudomonas fluorescens].	33.93	557	318	15	8	539	5	536	1e-82	284
rs:WP_031323200	DNA topoisomerase III [Pseudomonas stutzeri].	33.33	558	335	13	8	546	5	544	2e-82	283
rs:WP_024647908	DNA topoisomerase III [Pseudomonas syringae].	34.70	559	329	14	8	548	5	545	2e-82	284
rs:WP_010446576	DNA topoisomerase III [Pseudomonas fuscovaginae].	32.73	556	346	12	7	548	4	545	2e-82	283
rs:WP_016852000	DNA topoisomerase III [Pseudomonas aeruginosa].	32.39	568	347	14	4	552	1	550	2e-82	284
rs:WP_041013332	DNA topoisomerase III [Pseudomonas xanthomarina].	32.39	568	347	14	4	552	1	550	2e-82	284
rs:WP_038414121	DNA topoisomerase III [Pseudomonas cremoricolorata].	33.57	560	336	14	7	548	4	545	2e-82	284
rs:WP_012701283	DNA topoisomerase III [Azotobacter vinelandii].	32.69	566	345	14	1	548	1	548	2e-82	283
rs:WP_016446175	DNA topoisomerase III [Delftia acidovorans].	32.39	568	347	14	4	552	1	550	2e-82	284
rs:WP_024960098	DNA topoisomerase III [Pseudomonas syringae].	34.70	559	329	14	8	548	5	545	2e-82	284
tr:W0QQA8_9PAST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.85	551	337	13	8	539	24	560	2e-82	285
rs:WP_020192167	DNA topoisomerase III [Pseudomonas putida].	32.92	568	344	14	4	552	1	550	2e-82	284
rs:WP_017926600	hypothetical protein, partial [Thioalkalivibrio sp. HL-Eb18].	32.24	518	316	10	41	539	1	502	2e-82	285
rs:WP_042323003	DNA topoisomerase III [Burkholderia ginsengisoli].	33.33	561	337	13	8	549	5	547	2e-82	284
rs:WP_041931602	DNA topoisomerase III [Pseudomonas poae].	33.69	564	328	15	8	548	5	545	2e-82	283
rs:WP_004412596	DNA topoisomerase III [Pseudomonas syringae].	34.70	559	329	14	8	548	5	545	2e-82	283
rs:WP_043050240	DNA topoisomerase III [Pseudomonas fluorescens].	33.75	566	325	16	8	548	5	545	2e-82	283
rs:WP_032903512	DNA topoisomerase III [Pseudomonas fluorescens].	33.57	566	326	16	8	548	5	545	2e-82	283
gpu:CP011020_4761	DNA topoisomerase III [Pseudomonas chlororaphis]	33.39	557	321	14	8	539	5	536	2e-82	283
rs:WP_032870234	DNA topoisomerase III [Pseudomonas fluorescens].	33.69	564	328	15	8	548	5	545	2e-82	283
rs:WP_014620938	DNA topoisomerase III [Shewanella baltica].	34.24	552	321	15	7	540	4	531	2e-82	285
rs:WP_017462946	DNA topoisomerase III [Dyella ginsengisoli].	32.22	568	348	14	4	552	1	550	2e-82	284
rs:WP_003474339	DNA topoisomerase III [Xanthomonas translucens].	32.15	563	346	12	8	552	5	549	2e-82	283
rs:WP_033955548	DNA topoisomerase III [Pseudomonas aeruginosa].	32.04	568	349	13	4	552	1	550	2e-82	283
rs:WP_024889628	DNA topoisomerase III [Luteimonas huabeiensis].	31.87	568	350	13	4	552	1	550	2e-82	283
rs:WP_034104239	DNA topoisomerase III [Pseudomonas fluorescens].	33.27	559	337	14	8	548	5	545	2e-82	283
tr:F2Q8P5_SALEE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.21	557	342	13	7	549	4	544	3e-82	283
rs:WP_024673600	DNA topoisomerase III [Pseudomonas syringae].	34.35	559	331	14	8	548	5	545	3e-82	283
rs:WP_020325680	DNA topoisomerase III [Pseudomonas syringae].	34.53	559	330	14	8	548	5	545	3e-82	283
rs:WP_003451175	DNA topoisomerase III in PFGI-1-like cluster [Pseudomonas pseudoalcaligenes].	31.87	568	350	13	4	552	1	550	3e-82	283
rs:WP_029296576	DNA topoisomerase III [Pseudomonas fluorescens].	33.45	559	336	14	8	548	5	545	3e-82	283
rs:WP_012584772	DNA topoisomerase III [Thauera sp. MZ1T].	32.22	568	348	14	4	552	1	550	3e-82	283
rs:WP_039195103	DNA topoisomerase III [Actinobacillus suis].	31.78	557	349	13	8	548	5	546	3e-82	283
rs:WP_043157988	DNA topoisomerase III [Pseudomonas aeruginosa].	32.27	564	345	14	8	552	5	550	3e-82	283
rs:WP_046385324	DNA topoisomerase III [Pseudomonas veronii].	34.04	564	326	15	8	548	5	545	3e-82	283
rs:WP_044308340	DNA topoisomerase III [Pseudomonas syringae].	35.06	559	327	14	8	548	5	545	3e-82	283
rs:WP_034949922	DNA topoisomerase III, partial [Erwinia oleae].	33.15	549	337	11	8	539	5	540	3e-82	283
rs:WP_008075309	DNA topoisomerase III [Pseudomonas sp. GM79].	33.57	557	320	14	8	539	5	536	3e-82	283
rs:WP_033902057	DNA topoisomerase III [Pseudomonas sp. FH1].	33.87	564	327	15	8	548	5	545	3e-82	283
rs:WP_023045227	DNA topoisomerase III [Photorhabdus temperata].	32.86	560	341	14	8	548	5	548	3e-82	283
rs:WP_014701085	DNA topoisomerase [Pectobacterium sp. SCC3193].	32.09	564	350	12	8	553	5	553	3e-82	283
rs:WP_018879179	hypothetical protein, partial [Thioalkalivibrio sp. ALE9].	32.18	522	319	10	41	543	1	506	3e-82	284
rs:WP_044321692	DNA topoisomerase III [Pseudomonas amygdali].	34.53	559	330	14	8	548	5	545	3e-82	283
rs:WP_019332795	DNA topoisomerase III [Pseudomonas syringae].	32.26	561	343	13	8	549	5	547	3e-82	283
rs:WP_010846535	DNA topoisomerase III [Xenorhabdus nematophila].	33.33	540	328	12	8	531	5	528	3e-82	283
rs:WP_013721848	DNA topoisomerase III [Alicycliphilus denitrificans].	32.22	568	348	14	4	552	1	550	3e-82	283
rs:WP_046235877	DNA topoisomerase III [Pseudomonas syringae pv. coryli].	34.53	559	330	14	8	548	5	545	4e-82	283
rs:WP_024683169	DNA topoisomerase III [Pseudomonas syringae].	34.70	559	329	14	8	548	5	545	4e-82	283
rs:WP_016981353	DNA topoisomerase III [Pseudomonas amygdali].	34.53	559	330	14	8	548	5	545	4e-82	283
rs:WP_043220266	DNA topoisomerase III [Pseudomonas balearica].	32.25	555	348	12	8	548	5	545	4e-82	282
rs:WP_024689860	DNA topoisomerase III [Pseudomonas syringae].	34.35	559	331	14	8	548	5	545	5e-82	283
rs:WP_004255068	DNA topoisomerase III [Thauera sp. 63].	32.04	568	349	14	4	552	1	550	5e-82	283
rs:WP_006248877	DNA topoisomerase III [Mannheimia haemolytica].	33.04	560	340	15	8	548	5	548	5e-82	283
rs:WP_034031049	DNA topoisomerase III [Pseudomonas aeruginosa].	32.22	568	348	14	4	552	1	550	5e-82	283
rs:WP_019559093	hypothetical protein, partial [Thioalkalivibrio sp. ALE12].	32.10	514	322	9	41	539	1	502	5e-82	284
rs:WP_007997338	DNA topoisomerase III [Pseudomonas sp. GM49].	33.39	566	341	14	1	548	1	548	5e-82	282
rs:WP_038984222	DNA topoisomerase III [Pseudomonas fluorescens].	33.45	559	336	13	8	548	5	545	6e-82	282
rs:WP_005744254	DNA topoisomerase III [Pseudomonas amygdali].	34.53	559	330	14	8	548	5	545	6e-82	282
rs:WP_024664267	DNA topoisomerase III [Pseudomonas syringae].	34.70	559	329	14	8	548	5	545	6e-82	282
rs:WP_029573705	DNA topoisomerase III, partial [Pseudomonas syringae].	33.87	555	339	12	8	548	5	545	6e-82	280
rs:WP_014717974	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	33.39	566	327	16	8	548	5	545	6e-82	282
rs:WP_041104383	DNA topoisomerase III [Pseudomonas stutzeri].	32.45	564	344	13	8	552	5	550	6e-82	283
rs:WP_011334736	DNA topoisomerase III [Pseudomonas fluorescens].	33.63	559	335	13	8	548	5	545	6e-82	282
rs:WP_003410932	DNA topoisomerase III [Pseudomonas syringae].	33.63	553	325	12	8	539	5	536	6e-82	282
rs:WP_014620441	DNA topoisomerase III [Shewanella baltica].	34.00	553	321	16	7	540	4	531	7e-82	283
rs:WP_044311497	DNA topoisomerase III [Pseudomonas syringae].	34.70	559	329	14	8	548	5	545	7e-82	282
rs:WP_024692225	DNA topoisomerase III [Pseudomonas syringae].	34.70	559	329	14	8	548	5	545	7e-82	282
rs:WP_027607351	DNA topoisomerase III [Pseudomonas sp. LAMO17WK12:I2].	34.11	557	317	14	8	539	5	536	7e-82	282
rs:WP_043105734	DNA topoisomerase III [Pseudomonas aeruginosa].	31.69	568	351	13	4	552	1	550	7e-82	282
rs:WP_003141052	DNA topoisomerase III [Pseudomonas aeruginosa].	32.22	568	348	14	4	552	1	550	7e-82	282
rs:WP_044421241	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	34.35	559	331	14	8	548	5	545	8e-82	282
rs:WP_028389303	hypothetical protein [Legionella fairfieldensis].	33.69	558	338	15	7	548	4	545	8e-82	282
rs:WP_025214575	DNA topoisomerase III [Pseudomonas brassicacearum].	33.45	559	336	14	8	548	5	545	8e-82	281
tr:A0LAP8_MAGSM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.65	597	372	14	8	583	5	580	8e-82	284
rs:WP_003423916	DNA topoisomerase III [Pseudomonas syringae].	34.70	559	329	15	8	548	5	545	8e-82	282
rs:WP_011145395	DNA topoisomerase III [Photorhabdus luminescens].	32.86	560	341	14	8	548	5	548	9e-82	282
rs:WP_005779714	DNA topoisomerase III [Pseudomonas amygdali].	34.53	559	330	14	8	548	5	545	9e-82	282
rs:WP_045146249	DNA topoisomerase III [Escherichia coli].	32.53	578	353	13	8	563	5	567	9e-82	282
rs:WP_040269467	DNA topoisomerase III [Pseudomonas rhodesiae].	33.27	559	337	14	8	548	5	545	9e-82	281
rs:WP_037043705	DNA topoisomerase III [Pseudomonas sp. BAY1663].	32.26	561	343	14	7	548	4	546	9e-82	281
rs:WP_017709126	DNA topoisomerase III [Pseudomonas syringae].	34.35	559	331	14	8	548	5	545	9e-82	282
rs:WP_046270416	DNA topoisomerase III [Pseudomonas syringae].	34.35	559	331	14	8	548	5	545	1e-81	281
tr:A0A0A4GCQ0_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.11	557	317	14	8	539	5	536	1e-81	281
rs:WP_024669068	DNA topoisomerase III [Pseudomonas syringae].	34.17	559	332	14	8	548	5	545	1e-81	281
rs:WP_012438475	DNA topoisomerase III [Xanthomonas campestris].	31.56	564	348	13	8	552	5	549	1e-81	282
rs:WP_041105535	DNA topoisomerase III [Pseudomonas stutzeri].	32.25	555	348	12	8	548	5	545	1e-81	281
rs:WP_005786941	DNA topoisomerase III [Pseudomonas synxantha].	33.33	564	330	15	8	548	5	545	1e-81	281
rs:WP_013185201	DNA topoisomerase III [Xenorhabdus nematophila].	33.09	538	332	12	8	531	5	528	1e-81	281
rs:WP_011269736	DNA topoisomerase III [Xanthomonas campestris].	31.97	563	347	12	8	552	5	549	1e-81	282
rs:WP_024656059	DNA topoisomerase III [Pseudomonas syringae].	34.35	559	331	14	8	548	5	545	1e-81	281
rs:WP_034113353	DNA topoisomerase III [Pseudomonas fluorescens].	33.75	557	319	14	8	539	5	536	1e-81	281
rs:WP_024696781	DNA topoisomerase III [Pseudomonas syringae].	34.35	559	331	14	8	548	5	545	1e-81	281
rs:WP_028693701	DNA topoisomerase III [Pseudomonas cremoricolorata].	33.57	560	336	14	7	548	4	545	1e-81	281
rs:WP_006253622	DNA topoisomerase III [Mannheimia haemolytica].	32.50	560	343	14	8	548	5	548	1e-81	282
rs:WP_027898417	DNA topoisomerase III [Pseudomonas syringae].	33.27	562	335	16	7	548	4	545	1e-81	281
rs:WP_040244399	DNA topoisomerase III [Xanthomonas citri].	31.74	564	347	13	8	552	5	549	1e-81	281
rs:WP_011267044	DNA topoisomerase III [Pseudomonas syringae].	32.26	561	343	13	8	549	5	547	1e-81	281
rs:WP_008028166	DNA topoisomerase III [Pseudomonas sp. GM60].	33.45	559	336	14	8	548	5	545	1e-81	281
rs:WP_011839989	DNA topoisomerase III [Shewanella baltica].	34.00	553	321	16	7	540	4	531	1e-81	282
rs:WP_017134367	DNA topoisomerase III [Pseudomonas agarici].	32.01	556	350	11	7	548	4	545	1e-81	281
rs:WP_041979771	DNA topoisomerase III [Xenorhabdus nematophila].	33.83	541	327	14	8	531	5	531	1e-81	281
rs:WP_042827100	DNA topoisomerase III [Xanthomonas axonopodis].	31.91	564	346	14	8	552	5	549	1e-81	281
rs:WP_004418049	DNA topoisomerase III [Pseudomonas syringae].	34.53	559	330	14	8	548	5	545	1e-81	281
rs:WP_011051421	DNA topoisomerase III [Xanthomonas citri].	31.60	576	346	13	4	552	1	555	1e-81	281
tr:F3ET09_PSEA0	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.53	559	330	14	8	548	5	545	1e-81	281
rs:WP_005893387	DNA topoisomerase III [Pseudomonas coronafaciens].	34.17	559	332	14	8	548	5	545	1e-81	281
rs:WP_020361462	DNA topoisomerase III [Pseudomonas syringae].	32.44	561	342	14	8	549	5	547	2e-81	281
rs:WP_047100582	DNA topoisomerase III [Dickeya dianthicola].	32.04	540	337	11	7	530	4	529	2e-81	281
rs:WP_010436617	DNA topoisomerase III [Pseudomonas syringae].	34.53	559	330	14	8	548	5	545	2e-81	281
rs:WP_041474889	DNA topoisomerase III [Pseudomonas sp. UW4].	32.86	566	344	14	1	548	1	548	2e-81	281
rs:WP_004665587	DNA topoisomerase III [Pseudomonas savastanoi].	34.53	559	330	14	8	548	5	545	2e-81	281
rs:WP_016567955	DNA topoisomerase III [Pseudomonas syringae].	34.35	559	331	14	8	548	5	545	2e-81	281
rs:WP_038036807	DNA topoisomerase III [Thioalkalivibrio sp. ALE20].	31.58	513	331	8	43	543	1	505	2e-81	282
gp:AP006725_567	putative DNA topoisomerase [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]	33.60	503	303	9	53	539	1	488	2e-81	278
rs:WP_015471954	Topoisomerase IA [Xanthomonas citri].	31.56	564	348	13	8	552	5	549	2e-81	281
rs:WP_046720009	DNA topoisomerase III [Pseudomonas syringae].	32.26	561	343	13	8	549	5	547	2e-81	281
tr:F3C4Q0_PSESG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.53	559	330	14	8	548	5	545	2e-81	281
rs:WP_017701728	DNA topoisomerase III [Pseudomonas syringae].	34.35	559	331	14	8	548	5	545	2e-81	281
rs:WP_023125205	hypothetical protein [Pseudomonas aeruginosa].	32.04	568	349	14	4	552	1	550	2e-81	281
rs:WP_011168879	DNA topoisomerase III [Pseudomonas savastanoi].	34.53	559	330	14	8	548	5	545	2e-81	281
rs:WP_007246696	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	34.35	559	331	14	8	548	5	545	2e-81	281
rs:WP_019742482	DNA topoisomerase III [Pseudomonas savastanoi].	34.53	559	330	14	8	548	5	545	2e-81	281
rs:WP_003441919	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	33.99	559	333	14	8	548	5	545	2e-81	281
rs:WP_024642909	DNA topoisomerase III [Pseudomonas syringae].	34.88	559	328	14	8	548	5	545	2e-81	281
rs:WP_019821417	DNA topoisomerase III [Pseudomonas sp. CFT9].	33.39	566	327	16	8	548	5	545	2e-81	281
rs:WP_020306940	DNA topoisomerase III [Pseudomonas stutzeri].	32.55	556	346	11	8	548	5	546	2e-81	281
rs:WP_033482602	DNA topoisomerase III [Xanthomonas axonopodis].	31.56	564	348	13	8	552	5	549	2e-81	281
rs:WP_024420412	DNA topoisomerase III [Pseudomonas avellanae].	31.74	564	347	13	8	552	5	549	2e-81	281
rs:WP_029996170	DNA topoisomerase III [Xanthomonas axonopodis].	31.79	563	348	12	8	552	5	549	2e-81	281
tr:A0A0A8NYT3_XENNE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.83	541	327	14	8	531	11	537	2e-81	281
rs:WP_016567477	DNA topoisomerase III [Pseudomonas syringae].	32.26	561	343	13	8	549	5	547	2e-81	281
rs:WP_011793734	DNA topoisomerase III [Acidovorax citrulli].	31.58	570	345	11	7	549	4	555	2e-81	281
rs:WP_046027642	DNA topoisomerase III [Pseudomonas fluorescens].	33.27	559	337	13	8	548	5	545	2e-81	280
rs:WP_024914123	DNA topoisomerase III [Serratia fonticola].	33.46	541	330	12	7	530	4	531	2e-81	281
rs:WP_015276251	DNA topoisomerase III [Pseudomonas stutzeri].	32.19	556	348	12	8	548	5	546	2e-81	280
rs:WP_040239258	DNA topoisomerase III [Xanthomonas citri].	31.07	560	356	11	8	552	5	549	3e-81	281
rs:WP_025854478	DNA topoisomerase III [Pseudomonas sp. CHM02].	33.69	564	328	15	8	548	5	545	3e-81	280
rs:WP_042841609	DNA topoisomerase III [Xanthomonas euvesicatoria].	31.74	564	347	13	8	552	5	549	3e-81	281
tr:K9NKF5_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.09	559	338	14	8	548	5	545	3e-81	280
rs:WP_001175890	DNA topoisomerase III [Escherichia coli].	32.69	566	344	13	8	553	5	553	3e-81	281
rs:WP_011347486	DNA topoisomerase III [Xanthomonas euvesicatoria].	31.74	564	347	13	8	552	5	549	3e-81	281
rs:WP_017707803	DNA topoisomerase III [Pseudomonas syringae].	32.26	561	343	13	8	549	5	547	3e-81	281
rs:WP_008059727	DNA topoisomerase III [Pseudomonas sp. GM78].	33.45	559	336	14	8	548	5	545	3e-81	280
rs:WP_003296453	DNA topoisomerase III [Pseudomonas stutzeri].	32.51	566	341	15	8	552	5	550	3e-81	281
rs:WP_025389477	DNA topoisomerase III [Pseudomonas syringae].	34.35	559	331	14	8	548	5	545	3e-81	280
rs:WP_023444430	DNA topoisomerase III [Pseudomonas chloritidismutans].	33.04	560	338	13	8	548	5	546	3e-81	280
rs:WP_027903059	DNA topoisomerase III [Pseudomonas sp. URMO17WK12:I3].	33.45	559	336	14	8	548	5	545	3e-81	280
rs:WP_033470610	DNA topoisomerase III [Bordetella bronchiseptica].	32.27	564	345	14	8	552	5	550	3e-81	281
tr:J3IDL5_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.04	566	343	13	1	548	2	549	3e-81	280
rs:WP_003403627	DNA topoisomerase III [Pseudomonas syringae].	34.70	559	329	14	8	548	5	545	3e-81	280
rs:WP_021519870	hypothetical protein [Escherichia coli].	32.69	566	344	13	8	553	5	553	3e-81	281
rs:WP_046072708	DNA topoisomerase III [Pseudomonas fluorescens].	33.39	566	327	16	8	548	5	545	3e-81	280
rs:WP_023085000	hypothetical protein [Pseudomonas aeruginosa].	32.04	568	349	14	4	552	1	550	4e-81	280
rs:WP_025259685	DNA topoisomerase III [Pseudomonas cichorii].	33.45	559	336	14	8	548	5	545	4e-81	280
rs:WP_003381830	DNA topoisomerase III [Pseudomonas syringae].	34.17	559	332	14	8	548	5	545	4e-81	280
tr:J2T5I3_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.04	566	343	13	1	548	2	549	4e-81	280
rs:WP_007946260	DNA topoisomerase III [Pseudomonas sp. GM21].	33.45	559	336	13	8	548	5	545	4e-81	280
rs:WP_027979348	DNA topoisomerase III [gamma proteobacterium L18].	32.36	550	337	13	8	540	5	536	4e-81	280
rs:WP_024679664	DNA topoisomerase III [Pseudomonas syringae].	34.35	559	331	14	8	548	5	545	4e-81	280
rs:WP_032614657	DNA topoisomerase III [Pseudomonas syringae].	34.35	559	331	14	8	548	5	545	4e-81	280
rs:WP_045036739	DNA topoisomerase III [Photobacterium iliopiscarium].	34.57	541	328	17	8	539	5	528	4e-81	281
tr:F0V072_SALBN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.55	550	345	11	7	543	4	540	4e-81	280
rs:WP_024213397	DNA topoisomerase III [Escherichia coli].	32.69	566	344	13	8	553	5	553	4e-81	280
rs:WP_033990355	DNA topoisomerase III [Pseudomonas aeruginosa].	32.39	568	347	14	4	552	1	550	4e-81	280
rs:WP_024108348	DNA topoisomerase III [Dickeya dianthicola].	31.83	619	379	17	7	603	4	601	4e-81	280
rs:WP_046035426	DNA topoisomerase III [Pseudomonas fluorescens].	33.57	557	320	14	8	539	5	536	4e-81	280
rs:WP_016849630	DNA topoisomerase III [Xanthomonas axonopodis].	31.74	564	347	13	8	552	5	549	4e-81	280
rs:WP_044393820	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	31.91	561	345	13	8	549	5	547	4e-81	280
rs:WP_027620857	DNA topoisomerase III [Pseudomonas sp. URHB0015].	33.45	559	336	14	8	548	5	545	4e-81	280
rs:WP_024691435	DNA topoisomerase III [Pseudomonas syringae].	32.09	561	344	14	8	549	5	547	5e-81	280
rs:WP_044344117	DNA topoisomerase III [Pseudomonas meliae].	34.17	559	332	14	8	548	5	545	5e-81	280
rs:WP_017684788	DNA topoisomerase III [Pseudomonas syringae].	34.17	559	332	14	8	548	5	545	5e-81	280
rs:WP_027977778	DNA topoisomerase III [gamma proteobacterium L18].	33.09	559	338	14	8	548	5	545	5e-81	280
rs:WP_039767094	DNA topoisomerase III [Pseudomonas fluorescens].	33.63	559	335	13	8	548	5	545	5e-81	280
rs:WP_032830402	DNA topoisomerase III [Pseudomonas sp. GM79].	33.27	559	337	13	8	548	5	545	5e-81	280
rs:WP_020289917	DNA topoisomerase III [Pseudomonas sp. CFII64].	33.75	557	333	14	8	546	5	543	5e-81	280
rs:WP_024533180	DNA topoisomerase III [Pseudomonas syringae].	32.26	561	343	13	8	549	5	547	5e-81	280
rs:WP_010798937	DNA topoisomerase III [Pseudomonas sp. HPB0071].	33.21	557	340	13	8	548	5	545	5e-81	280
rs:WP_011104028	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	34.35	559	331	14	8	548	5	545	5e-81	280
rs:WP_005738886	DNA topoisomerase III [Pseudomonas amygdali].	34.58	561	329	14	8	548	5	547	5e-81	280
rs:WP_046620732	DNA topoisomerase III [Pseudomonas stutzeri].	33.21	560	337	14	8	548	5	546	6e-81	279
rs:WP_008367437	DNA topoisomerase III [Pseudomonas sp. M47T1].	33.57	560	334	15	8	548	5	545	6e-81	279
rs:WP_014597325	DNA topoisomerase III [Pseudomonas stutzeri].	32.37	556	347	11	8	548	5	546	6e-81	279
tr:F3GYQ3_PSESX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	34.82	560	329	14	7	548	4	545	6e-81	282
rs:WP_026013519	DNA topoisomerase III [Pseudomonas fluorescens].	33.45	559	336	14	8	548	5	545	7e-81	279
rs:WP_032834930	DNA topoisomerase III [Pseudomonas sp. GM50].	33.27	559	337	13	8	548	5	545	7e-81	279
rs:WP_033836471	DNA topoisomerase III [Xanthomonas citri].	31.74	564	347	14	8	552	5	549	7e-81	280
rs:WP_005577632	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	30.47	558	360	12	8	550	5	549	7e-81	280
rs:WP_039763141	DNA topoisomerase III [Pseudomonas fluorescens].	33.81	559	334	13	8	548	5	545	7e-81	279
rs:WP_005617548	DNA topoisomerase III [Pseudomonas avellanae].	33.99	559	333	14	8	548	5	545	7e-81	279
rs:WP_024109633	MULTISPECIES: DNA topoisomerase III [Dickeya].	31.85	540	338	11	7	530	4	529	7e-81	280
tr:J2SQG3_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.27	559	337	14	8	548	5	545	8e-81	279
rs:WP_044187714	DNA topoisomerase III [Escherichia coli].	32.69	566	344	13	8	553	5	553	8e-81	280
rs:WP_039584862	DNA topoisomerase III [Xanthomonas axonopodis].	31.74	564	347	13	8	552	5	549	8e-81	280
rs:WP_043302582	DNA topoisomerase III [Pseudomonas sp. GM55].	33.04	566	343	14	1	548	1	548	8e-81	279
tr:A0A085V3L4_PSESX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.75	557	333	14	8	546	5	543	8e-81	279
rs:WP_008568568	DNA topoisomerase III [Pseudomonas sp. Chol1].	32.69	566	345	14	1	548	1	548	9e-81	279
rs:WP_025111358	DNA topoisomerase III [Pseudomonas sp. H1h].	33.09	559	338	13	8	548	5	545	9e-81	279
rs:WP_010172260	DNA topoisomerase III [Pseudomonas sp. PAMC 25886].	33.45	559	336	14	8	548	5	545	9e-81	279
rs:WP_016775107	DNA topoisomerase III, partial [Pseudomonas sp. R62].	33.81	559	334	13	8	548	5	545	9e-81	278
rs:WP_024799102	DNA topoisomerase III [Salmonella enterica].	32.04	568	358	11	7	559	4	558	9e-81	279
rs:WP_024661467	DNA topoisomerase III [Pseudomonas syringae].	32.09	561	344	13	8	549	5	547	9e-81	280
rs:WP_041073385	DNA topoisomerase III [Pseudomonas sp. W15Feb9B].	33.09	559	338	13	8	548	5	545	9e-81	279
rs:WP_046833637	DNA topoisomerase III [Xanthomonas axonopodis].	31.56	564	348	13	8	552	5	549	9e-81	279
rs:WP_001242113	DNA topoisomerase III [Escherichia coli].	32.36	581	350	14	8	563	5	567	9e-81	279
rs:WP_019335150	DNA topoisomerase III [Pseudomonas syringae].	32.26	561	343	13	8	549	5	547	9e-81	279
rs:WP_003300857	DNA topoisomerase III [Pseudomonas stutzeri].	32.68	560	340	13	8	548	5	546	1e-80	279
rs:WP_019690070	DNA topoisomerase III [Pseudomonas fluorescens].	33.27	559	337	14	8	548	5	545	1e-80	279
rs:WP_032881001	DNA topoisomerase III [Pseudomonas sp. BRG-100].	33.16	564	331	15	8	548	5	545	1e-80	279
rs:WP_024667013	DNA topoisomerase III [Pseudomonas syringae].	31.91	561	345	13	8	549	5	547	1e-80	279
rs:WP_013185062	DNA topoisomerase III [Xenorhabdus nematophila].	33.52	540	327	12	8	531	5	528	1e-80	279
rs:WP_015879466	DNA topoisomerase III [Tolumonas auensis].	32.09	564	346	13	8	552	5	550	1e-80	279
rs:WP_013185129	DNA topoisomerase III [Xenorhabdus nematophila].	33.27	538	331	12	8	531	5	528	1e-80	279
rs:WP_041023653	DNA topoisomerase III [Pseudomonas sp. SHC52].	32.92	559	339	14	8	548	5	545	1e-80	278
rs:WP_046832659	DNA topoisomerase III [Pseudomonas amygdali].	32.26	561	343	13	8	549	5	547	1e-80	279
rs:WP_013792850	DNA topoisomerase III [Pseudomonas fulva].	33.57	560	336	15	7	548	4	545	1e-80	278
rs:WP_044783964	DNA topoisomerase III [Escherichia coli].	32.51	566	345	13	8	553	5	553	1e-80	279
rs:WP_038851309	DNA topoisomerase III [Pseudomonas fluorescens].	33.27	559	337	14	8	548	5	545	1e-80	278
rs:WP_033884893	DNA topoisomerase III [Escherichia coli].	32.69	566	344	13	8	553	5	553	1e-80	279
rs:WP_032211070	DNA topoisomerase III [Escherichia coli].	32.51	566	345	13	8	553	5	553	2e-80	279
rs:WP_020342662	DNA topoisomerase III [Pseudomonas syringae].	32.09	561	344	13	8	549	5	547	2e-80	279
rs:WP_003425069	DNA topoisomerase III [Pseudomonas syringae].	32.09	561	344	13	8	549	5	547	2e-80	279
rs:WP_020798536	DNA topoisomerase III [Pseudomonas sp. G5(2012)].	33.27	559	337	14	8	548	5	545	2e-80	278
rs:WP_019364549	DNA topoisomerase III [Pseudomonas luteola].	33.21	557	340	13	8	548	5	545	2e-80	278
rs:WP_038657937	DNA topoisomerase III [Pseudomonas stutzeri].	32.86	560	339	14	8	548	5	546	2e-80	278
rs:WP_008151456	DNA topoisomerase III [Pseudomonas sp. GM41(2012)].	33.27	559	337	14	8	548	5	545	2e-80	278
rs:WP_003211612	DNA topoisomerase III [Pseudomonas fluorescens].	32.97	555	344	12	8	548	5	545	2e-80	278
rs:WP_023443922	DNA topoisomerase III [Pseudomonas chloritidismutans].	31.87	568	350	14	4	552	1	550	2e-80	278
rs:WP_038182493	DNA topoisomerase III [Xenorhabdus bovienii].	33.21	536	332	12	8	531	5	526	2e-80	278
rs:WP_001562956	DNA topoisomerase III [Escherichia coli].	32.69	566	344	13	8	553	5	553	2e-80	279
rs:WP_005771280	DNA topoisomerase III [Pseudomonas amygdali].	34.17	559	332	14	8	548	5	545	2e-80	278
rs:WP_017530155	DNA topoisomerase III [Pseudomonas fluorescens].	33.64	550	329	15	8	539	5	536	2e-80	278
tr:F2Q883_SALBN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.43	555	340	11	7	543	4	541	2e-80	278
rs:WP_001175889	DNA topoisomerase III [Escherichia coli].	32.51	566	345	13	8	553	5	553	2e-80	278
rs:WP_045158624	DNA topoisomerase III [Pseudomonas stutzeri].	32.32	557	348	10	7	548	4	546	2e-80	278
rs:WP_042558370	DNA topoisomerase III [Pseudomonas fluorescens].	33.69	558	318	16	8	539	5	536	2e-80	278
rs:WP_011267536	DNA topoisomerase III [Pseudomonas syringae].	34.70	559	329	14	8	548	5	545	2e-80	278
rs:WP_039431367	DNA topoisomerase III [Xanthomonas vasicola].	31.56	564	348	13	8	552	5	549	2e-80	278
tr:F3CKY0_PSESG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.73	561	346	13	8	549	5	547	2e-80	276
rs:WP_044705513	DNA topoisomerase III [Escherichia coli].	32.69	566	344	13	8	553	5	553	2e-80	278
rs:WP_046048951	DNA topoisomerase III [Pseudomonas fluorescens].	33.27	559	337	14	8	548	5	545	2e-80	278
rs:WP_016781518	DNA topoisomerase III [Pseudomonas fragi].	33.27	559	337	14	8	548	5	545	2e-80	278
rs:WP_007950567	DNA topoisomerase III [Pseudomonas sp. GM25].	33.45	559	336	13	8	548	5	545	2e-80	278
rs:WP_024013263	DNA topoisomerase III [Pseudomonas moraviensis].	33.63	559	335	14	8	548	5	545	3e-80	278
rs:WP_024647114	DNA topoisomerase III [Pseudomonas syringae].	34.17	559	332	14	8	548	5	545	3e-80	278
rs:WP_008435880	DNA topoisomerase III [Pseudomonas sp. Ag1].	32.97	555	344	12	8	548	5	545	3e-80	278
rs:WP_043293257	DNA topoisomerase III [Pseudomonas sp. LAMO17WK12:I2].	32.92	559	339	14	8	548	5	545	3e-80	278
rs:WP_042906600	DNA topoisomerase III, partial [Haemophilus parasuis].	32.13	554	334	14	8	538	5	539	3e-80	277
rs:WP_045156433	DNA topoisomerase III [Pseudomonas fluorescens].	32.92	559	339	14	8	548	5	545	3e-80	277
rs:WP_046817480	DNA topoisomerase III [Pseudomonas putida].	33.09	559	338	14	8	548	5	545	3e-80	277
rs:WP_044311780	DNA topoisomerase III [Pseudomonas syringae].	32.09	561	344	13	8	549	5	547	3e-80	278
rs:WP_017475477	DNA topoisomerase III [Pseudomonas sp. PAMC 26793].	32.97	555	344	12	8	548	5	545	3e-80	277
rs:WP_039589247	DNA topoisomerase III [Pseudomonas frederiksbergensis].	32.92	559	339	14	8	548	5	545	3e-80	277
rs:WP_037009569	DNA topoisomerase III, partial [Pseudomonas sp. RL].	31.98	566	342	15	8	550	5	550	4e-80	276
rs:WP_047293557	DNA topoisomerase III [Pseudomonas fluorescens].	32.61	555	346	12	8	548	5	545	4e-80	277
rs:WP_001696682	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	32.01	578	356	13	8	563	5	567	4e-80	278
rs:WP_032627286	DNA topoisomerase III [Pseudomonas syringae].	33.21	554	340	14	8	546	5	543	4e-80	277
rs:WP_045161316	DNA topoisomerase III [Pseudomonas stutzeri].	33.27	562	337	14	7	548	4	547	4e-80	277
rs:WP_034152903	DNA topoisomerase III [Pseudomonas fluorescens].	33.27	559	337	13	8	548	5	545	5e-80	277
rs:WP_044293632	DNA topoisomerase III [Pseudomonas amygdali].	31.91	561	345	13	8	549	5	547	5e-80	277
rs:WP_023122311	hypothetical protein [Pseudomonas aeruginosa].	31.74	564	348	12	8	552	5	550	5e-80	277
rs:WP_020358329	DNA topoisomerase III [Pseudomonas syringae].	31.74	564	348	13	8	552	5	550	5e-80	277
rs:WP_024638443	DNA topoisomerase III [Pseudomonas syringae].	34.05	555	338	12	8	548	5	545	5e-80	277
rs:WP_045492462	DNA topoisomerase III [Pseudomonas sp. StFLB209].	32.50	560	342	13	7	548	4	545	5e-80	277
rs:WP_014994483	MULTISPECIES: DNA topoisomerase III [Alcanivorax].	32.38	562	344	13	4	539	1	552	6e-80	278
rs:WP_039607434	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	32.09	561	344	13	8	549	5	547	6e-80	277
rs:WP_023226745	DNA topoisomerase III [Salmonella enterica].	31.94	551	348	10	7	543	4	541	6e-80	277
rs:WP_033054459	DNA topoisomerase III [Pseudomonas mandelii].	33.27	559	337	14	8	548	5	545	6e-80	276
rs:WP_046056719	DNA topoisomerase III [Pseudomonas fluorescens].	33.27	559	337	14	8	548	5	545	6e-80	276
rs:WP_002553877	DNA topoisomerase III [Pseudomonas savastanoi].	34.53	559	330	14	8	548	5	545	7e-80	277
rs:WP_033042013	DNA topoisomerase III [Pseudomonas putida].	33.09	559	338	14	8	548	5	545	7e-80	276
rs:WP_021112534	DNA topoisomerase III family protein [Haemophilus parasuis].	32.13	554	334	14	8	538	5	539	8e-80	277
rs:WP_030130788	DNA topoisomerase III [Pseudomonas sp. QTF5].	33.45	559	336	13	8	548	5	545	8e-80	276
rs:WP_019342298	DNA topoisomerase III [Pseudomonas stutzeri].	33.39	566	334	14	8	548	5	552	9e-80	276
tr:A0A031GBJ2_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.27	559	337	14	8	548	5	545	9e-80	276
rs:WP_043357816	hypothetical protein, partial [Cupriavidus basilensis].	32.38	559	341	17	8	544	5	548	1e-79	276
tr:G9ESR0_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.21	548	327	15	8	535	5	533	1e-79	276
rs:WP_010206575	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	31.91	564	347	13	8	552	5	550	1e-79	276
rs:WP_019411547	DNA topoisomerase III [Pseudomonas psychrophila].	33.09	559	338	14	8	548	5	545	1e-79	276
rs:WP_010835677	DNA topoisomerase III [Salmonella enterica].	31.75	570	342	14	8	553	5	551	1e-79	276
rs:WP_001241572	DNA topoisomerase III [Salmonella enterica].	31.94	551	348	10	7	543	4	541	1e-79	276
rs:WP_014753667	DNA topoisomerase III [Pseudomonas putida].	32.25	552	342	13	8	544	5	539	1e-79	276
tr:W4RYY9_9XANT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.20	518	313	11	52	549	1	505	1e-79	275
rs:WP_047227795	DNA topoisomerase III [Pseudomonas brassicacearum].	33.27	559	337	14	8	548	5	545	1e-79	276
rs:WP_045057706	DNA topoisomerase III [Pseudomonas sp. ES3-33].	32.61	555	346	12	8	548	5	545	1e-79	276
rs:WP_024677692	DNA topoisomerase III [Pseudomonas syringae].	31.91	561	345	13	8	549	5	547	1e-79	276
tr:J2MLI7_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.39	566	341	13	1	548	1	548	2e-79	275
rs:WP_047276194	DNA topoisomerase III [Pseudomonas fluorescens].	33.27	559	337	14	8	548	5	545	2e-79	275
rs:WP_024652300	DNA topoisomerase III [Pseudomonas syringae].	34.53	559	330	14	8	548	5	545	2e-79	276
rs:WP_008077315	DNA topoisomerase III [Pseudomonas sp. GM80].	33.27	559	337	13	8	548	5	545	2e-79	275
rs:WP_024650185	DNA topoisomerase III [Pseudomonas syringae].	31.91	561	345	13	8	549	5	547	2e-79	276
rs:WP_042705047	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	33.63	559	335	13	8	548	5	545	2e-79	275
rs:WP_019098998	DNA topoisomerase III [Pseudomonas putida].	32.61	552	340	13	8	544	5	539	2e-79	275
rs:WP_024676485	DNA topoisomerase III [Pseudomonas syringae].	33.99	559	333	14	8	548	5	545	2e-79	275
rs:WP_044807771	DNA topoisomerase III [Escherichia coli].	32.51	566	345	13	8	553	5	553	2e-79	276
rs:WP_007247388	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	31.91	561	345	13	8	549	5	547	2e-79	276
rs:WP_038441873	DNA topoisomerase III [Pseudomonas fluorescens].	33.09	559	338	14	8	548	5	545	3e-79	275
rs:WP_010565137	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	33.51	558	319	16	8	539	5	536	3e-79	275
rs:WP_035234763	DNA topoisomerase III [Alcanivorax sp. 19-m-6].	33.69	558	322	13	8	537	5	542	3e-79	277
rs:WP_044323396	DNA topoisomerase III [Pseudomonas amygdali].	34.35	559	331	14	8	548	5	545	3e-79	275
rs:WP_044345499	DNA topoisomerase III [Pseudomonas meliae].	31.55	561	347	13	8	549	5	547	3e-79	275
rs:WP_005787064	DNA topoisomerase III [Pseudomonas synxantha].	33.15	558	321	16	8	539	5	536	3e-79	275
rs:WP_015606321	DNA topoisomerase III [Salmonella enterica].	31.94	551	348	10	7	543	4	541	3e-79	275
rs:WP_042197545	DNA topoisomerase III [Escherichia coli].	32.92	571	333	12	8	556	5	547	3e-79	275
rs:WP_038366492	DNA topoisomerase III [Pseudomonas chlororaphis].	33.27	559	337	14	8	548	5	545	3e-79	275
rs:WP_012723395	DNA topoisomerase III [Pseudomonas fluorescens].	33.51	564	329	15	8	548	5	545	4e-79	275
rs:WP_039290396	DNA topoisomerase III [Pectobacterium atrosepticum].	31.93	545	333	13	7	530	4	531	4e-79	275
rs:WP_012315136	MULTISPECIES: DNA topoisomerase III [Pseudomonas putida group].	31.88	552	344	14	8	544	5	539	4e-79	275
tr:Q6D9T7_PECAS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.93	545	333	13	7	530	5	532	4e-79	275
rs:WP_042559616	DNA topoisomerase III [Pseudomonas fluorescens].	33.09	559	338	13	8	548	5	545	4e-79	274
rs:WP_005732953	DNA topoisomerase III [Pseudomonas amygdali].	34.35	559	331	14	8	548	5	545	4e-79	275
rs:WP_044319251	DNA topoisomerase III [Pseudomonas amygdali].	34.17	559	332	14	8	548	5	545	4e-79	275
rs:WP_042609385	DNA topoisomerase III [Pseudomonas fluorescens].	33.63	559	335	14	8	548	5	545	5e-79	274
rs:WP_047294473	DNA topoisomerase III [Pseudomonas fluorescens].	33.27	559	337	14	8	548	5	545	5e-79	274
rs:WP_027611731	DNA topoisomerase III [Pseudomonas sp. URIL14HWK12:I6].	32.92	559	339	14	8	548	5	545	5e-79	274
rs:WP_047275872	DNA topoisomerase III [Pseudomonas fluorescens].	33.09	559	338	14	8	548	5	545	6e-79	274
rs:WP_034119183	DNA topoisomerase III [Pseudomonas fluorescens].	32.98	564	332	15	8	548	5	545	6e-79	274
rs:WP_012052641	MULTISPECIES: DNA topoisomerase III [Pseudomonas putida group].	32.61	555	335	15	8	544	5	538	6e-79	274
rs:WP_046035969	DNA topoisomerase III [Pseudomonas fluorescens].	33.33	564	330	15	8	548	5	545	6e-79	274
rs:WP_044159002	DNA topoisomerase III [Enterobacter cloacae].	30.35	593	380	14	7	581	4	581	6e-79	275
rs:WP_047280872	DNA topoisomerase III [Pseudomonas fluorescens].	33.09	559	338	14	8	548	5	545	6e-79	274
rs:WP_016486405	DNA topoisomerase III [Pseudomonas putida].	32.61	552	340	14	8	544	5	539	6e-79	274
rs:WP_027925328	DNA topoisomerase III [Pseudomonas sp. URMO17WK12:I12].	33.27	559	337	13	8	548	5	545	6e-79	274
rs:WP_028940230	DNA topoisomerase III [Pseudomonas umsongensis].	33.27	559	337	14	8	548	5	545	7e-79	274
rs:WP_019579443	DNA topoisomerase III [Pseudomonas mandelii].	33.27	559	337	14	8	548	5	545	7e-79	274
rs:WP_017430535	DNA topoisomerase III [Halomonas jeotgali].	30.63	591	378	16	7	584	4	575	7e-79	273
rs:WP_005730106	DNA topoisomerase III [Pseudomonas amygdali].	31.37	561	348	13	8	549	5	547	7e-79	274
rs:WP_038612558	DNA topoisomerase III [Pseudomonas alkylphenolia].	34.29	560	332	14	7	548	4	545	7e-79	274
rs:WP_010459568	DNA topoisomerase III [Pseudomonas mandelii].	33.09	559	338	13	8	548	5	545	8e-79	274
rs:WP_026345770	DNA topoisomerase III [Pseudomonas sp. 45MFCol3.1].	33.09	559	338	14	8	548	5	545	8e-79	273
rs:WP_025443192	hypothetical protein [Vibrio parahaemolyticus].	32.90	535	341	10	7	530	5	532	9e-79	273
rs:WP_039587992	DNA topoisomerase III [Xanthomonas axonopodis].	31.38	564	349	13	8	552	5	549	9e-79	274
rs:WP_047282777	DNA topoisomerase III [Pseudomonas fluorescens].	33.09	559	338	14	8	548	5	545	9e-79	273
rs:WP_017339501	DNA topoisomerase III [Pseudomonas fluorescens].	32.57	568	329	15	8	548	5	545	1e-78	273
tr:A0A087FB29_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.26	561	343	14	4	545	1	543	1e-78	274
rs:WP_025163529	DNA topoisomerase III [Pseudomonas taeanensis].	32.25	555	348	12	8	548	5	545	1e-78	273
rs:WP_010211314	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	33.09	559	338	14	8	548	5	545	1e-78	273
rs:WP_014338649	DNA topoisomerase III [Pseudomonas fluorescens].	32.74	559	340	14	8	548	5	545	1e-78	273
rs:WP_041480830	DNA topoisomerase III [Pseudomonas sp. PTA1].	33.27	559	337	14	8	548	5	545	1e-78	273
rs:WP_017124649	DNA topoisomerase III [Pseudomonas gingeri].	32.25	555	348	12	8	548	5	545	1e-78	273
rs:WP_040069566	DNA topoisomerase III [Pseudomonas batumici].	32.19	556	349	12	7	548	4	545	1e-78	273
rs:WP_024618692	DNA topoisomerase III [Pseudomonas fluorescens].	32.74	559	340	14	8	548	5	545	1e-78	273
rs:WP_046336194	DNA topoisomerase III [Xenorhabdus bovienii].	32.78	540	333	12	8	531	5	530	1e-78	273
rs:WP_023653786	DNA topoisomerase III [Erwinia piriflorinigrans].	31.74	545	339	11	8	534	5	534	2e-78	273
rs:WP_046062077	DNA topoisomerase III [Pseudomonas kilonensis].	32.74	559	340	14	8	548	5	545	2e-78	273
rs:WP_030137934	DNA topoisomerase III [Pseudomonas fluorescens].	32.56	559	341	14	8	548	5	545	2e-78	273
rs:WP_042571552	DNA topoisomerase III [Pseudomonas simiae].	33.09	559	338	14	8	548	5	545	2e-78	273
tr:A0A0C4YA37_9BURK	SubName: Full=Cupriavidus basilensis strain 4G11 chromosome secondary, complete sequence {ECO:0000313|EMBL:AJG22342.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AJG22342.1};	32.38	559	341	17	8	544	5	548	2e-78	276
rs:WP_016913643	DNA topoisomerase III [Halomonas stevensii].	31.70	593	368	18	7	584	4	574	2e-78	273
tr:A0A0B0VM59_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.69	566	344	13	8	553	5	553	2e-78	273
rs:WP_018611357	DNA topoisomerase III [Pseudomonas sp. CFII68].	32.74	559	340	14	8	548	5	545	2e-78	273
tr:A0A0B6X433_XENBV	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.78	540	333	12	8	531	11	536	2e-78	273
rs:WP_042059062	DNA topoisomerase III [Acidomonas methanolica].	32.09	561	342	14	8	548	5	546	2e-78	273
rs:WP_046809689	DNA topoisomerase III [Pseudomonas psychrophila].	33.09	559	338	14	8	548	5	545	2e-78	272
rs:WP_019828878	DNA topoisomerase III [Pseudomonas sp. CF149].	33.09	559	338	14	8	548	5	545	2e-78	272
rs:WP_014542454	DNA topoisomerase III [Erwinia sp. Ejp617].	31.74	545	339	11	8	534	5	534	2e-78	273
gp:CP010896_1975	DNA topoisomerase III [Pseudomonas fluorescens]	33.09	559	338	14	8	548	7	547	2e-78	272
tr:U1S6K3_PSEFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.09	559	338	14	8	548	7	547	2e-78	272
rs:WP_031291485	DNA topoisomerase III [Pseudomonas fluorescens].	33.09	559	338	14	8	548	5	545	3e-78	272
rs:WP_013095152	DNA topoisomerase III [Enterobacter cloacae].	30.35	593	380	14	7	581	4	581	3e-78	274
rs:WP_007966854	DNA topoisomerase III [Pseudomonas sp. GM30].	33.27	559	337	13	8	548	5	545	3e-78	272
gp:CP005975_5245	DNA topoisomerase III [Pseudomonas fluorescens PICF7]	32.92	559	339	14	8	548	7	547	3e-78	272
rs:WP_044288115	DNA topoisomerase III [Pseudomonas fluorescens].	33.09	559	338	14	8	548	5	545	3e-78	272
rs:WP_045792448	DNA topoisomerase III [Pseudomonas fluorescens].	32.92	559	339	14	8	548	5	545	3e-78	272
tr:A9N2T9_SALPB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.60	562	360	12	7	553	4	550	3e-78	273
rs:WP_012988057	DNA topoisomerase III [Xenorhabdus bovienii].	32.53	538	335	12	8	531	5	528	3e-78	272
rs:WP_001750506	DNA topoisomerase III [Salmonella enterica].	31.45	601	368	14	8	581	5	588	4e-78	273
rs:WP_032308776	DNA topoisomerase III [Escherichia coli].	31.03	580	359	14	8	563	5	567	4e-78	272
rs:WP_021544269	hypothetical protein [Escherichia coli].	31.03	580	359	14	8	563	5	567	4e-78	272
rs:WP_031849828	hypothetical protein [Vibrio parahaemolyticus].	31.61	598	387	13	7	591	5	593	4e-78	271
rs:WP_024792519	DNA topoisomerase III [Salmonella enterica].	30.60	562	360	12	7	553	4	550	4e-78	272
rs:WP_042762169	hypothetical protein [Vibrio parahaemolyticus].	31.27	614	395	14	7	602	5	609	4e-78	271
rs:WP_033064134	DNA topoisomerase III [Pseudomonas sp. GM18].	33.27	559	337	14	8	548	5	545	4e-78	271
rs:WP_038263715	DNA topoisomerase III [Xenorhabdus cabanillasii].	34.01	541	329	12	7	532	4	531	4e-78	272
rs:WP_001682052	DNA topoisomerase III [Escherichia coli].	31.09	579	359	14	8	563	5	566	4e-78	272
rs:WP_039507416	DNA topoisomerase III [Pectobacterium carotovorum].	30.87	541	344	10	7	530	4	531	5e-78	272
rs:WP_001241569	DNA topoisomerase III [Salmonella enterica].	31.64	591	373	13	7	581	4	579	5e-78	272
tr:J2NSS9_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.04	566	343	14	1	548	1	548	5e-78	271
rs:WP_009099470	DNA topoisomerase III [Halomonas sp. GFAJ-1].	30.56	589	381	16	7	584	4	575	5e-78	271
gpu:CP011020_4882	DNA topoisomerase III [Pseudomonas chlororaphis]	32.56	559	341	13	8	548	5	545	6e-78	271
rs:WP_038855881	DNA topoisomerase III [Pseudomonas fluorescens].	33.39	557	321	14	8	539	5	536	7e-78	271
rs:WP_003226035	DNA topoisomerase III [Pseudomonas fluorescens].	32.92	559	339	13	8	548	5	545	9e-78	271
rs:WP_042732096	DNA topoisomerase III [Pseudomonas fluorescens].	32.56	559	341	13	8	548	5	545	1e-77	270
rs:WP_004252369	DNA topoisomerase III [Proteus mirabilis].	32.57	571	335	13	8	556	5	547	1e-77	271
rs:WP_004245767	DNA topoisomerase III [Proteus mirabilis].	32.57	571	335	13	8	556	5	547	1e-77	271
rs:WP_036941675	DNA topoisomerase III [Providencia stuartii].	32.22	571	337	12	8	556	5	547	1e-77	271
rs:WP_000765274	DNA topoisomerase III [Escherichia coli].	32.57	571	335	13	8	556	5	547	1e-77	271
rs:WP_007180672	DNA topoisomerase III [Burkholderia sp. Ch1-1].	31.50	565	348	13	8	552	5	550	1e-77	271
rs:WP_040262903	DNA topoisomerase III [Pseudomonas sp. CB1].	31.02	590	344	11	8	548	5	580	1e-77	271
rs:WP_043042072	DNA topoisomerase III [Pseudomonas fluorescens].	33.27	559	337	14	8	548	5	545	1e-77	270
rs:WP_004362285	DNA topoisomerase III [Thauera phenylacetica].	31.74	564	348	13	8	552	5	550	1e-77	271
rs:WP_033808633	DNA topoisomerase III [Escherichia coli].	31.03	580	359	14	8	563	5	567	1e-77	271
rs:WP_004239734	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	32.22	571	337	12	8	556	5	547	2e-77	271
rs:WP_032676550	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	30.43	562	361	12	7	553	4	550	2e-77	270
rs:WP_018929752	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	32.92	559	339	14	8	548	5	545	2e-77	270
rs:WP_027912566	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	33.09	559	338	14	8	548	5	545	2e-77	270
rs:WP_013692697	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	33.09	559	338	14	8	548	5	545	2e-77	270
rs:WP_032860216	DNA topoisomerase III [Pseudomonas sp. FH4].	32.74	559	340	14	8	548	5	545	2e-77	270
rs:WP_043190411	DNA topoisomerase III [Pseudomonas rhizosphaerae].	33.03	557	337	14	8	546	5	543	2e-77	269
rs:WP_004575589	DNA topoisomerase III [Pseudomonas putida].	32.07	552	343	13	8	544	5	539	2e-77	270
rs:WP_046856132	DNA topoisomerase III [Pseudomonas sp. CCOS191].	31.88	552	344	13	8	544	5	539	2e-77	270
rs:WP_032492626	DNA topoisomerase III [Pseudomonas putida].	32.26	561	343	13	8	549	5	547	2e-77	270
rs:WP_003180391	DNA topoisomerase III [Pseudomonas fluorescens].	32.38	559	342	14	8	548	5	545	2e-77	270
rs:WP_010385040	DNA topoisomerase III [Pseudoalteromonas rubra].	31.21	612	386	17	8	602	5	598	3e-77	270
rs:WP_043298804	DNA topoisomerase III [Pseudomonas sp. HMP271].	31.98	566	349	13	1	548	1	548	3e-77	270
rs:WP_041981894	DNA topoisomerase III [Xenorhabdus nematophila].	32.66	542	333	12	8	531	5	532	3e-77	270
rs:WP_003200140	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	33.09	559	338	14	8	548	5	545	3e-77	270
rs:WP_046497084	DNA topoisomerase III [Citrobacter amalonaticus].	30.43	562	361	12	7	553	4	550	3e-77	270
rs:WP_044393699	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	31.73	561	346	13	8	549	5	547	3e-77	270
tr:A0A0A8LKP9_XENNE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.66	542	333	12	8	531	11	538	3e-77	270
rs:WP_044707194	DNA topoisomerase III [Escherichia coli].	30.86	580	360	14	8	563	5	567	3e-77	270
rs:WP_007249706	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	33.63	559	335	14	8	548	5	545	3e-77	270
rs:WP_042678050	DNA topoisomerase III [Pantoea sp. B40].	31.52	552	347	12	7	540	4	542	3e-77	270
tr:A4VNK8_PSEU5	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.50	523	328	10	41	548	1	513	4e-77	268
rs:WP_012723224	DNA topoisomerase III [Pseudomonas fluorescens].	32.80	558	323	16	8	539	5	536	4e-77	269
rs:WP_022622166	DNA topoisomerase III [Pantoea ananatis].	31.77	554	343	13	7	540	4	542	4e-77	270
tr:M4JXQ1_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.08	532	314	13	40	548	16	528	4e-77	268
rs:WP_046337393	DNA topoisomerase III [Xenorhabdus bovienii].	33.33	537	331	11	8	530	5	528	4e-77	270
rs:WP_042103769	DNA topoisomerase III [Escherichia coli].	30.86	580	360	14	8	563	5	567	4e-77	270
rs:WP_041642718	DNA topoisomerase III, partial [Magnetococcus marinus].	30.50	564	354	13	41	583	1	547	5e-77	268
rs:WP_023047535	DNA topoisomerase III [Pseudomonas putida].	32.07	552	343	13	8	544	5	539	5e-77	269
rs:WP_024960796	DNA topoisomerase III [Pseudomonas syringae].	31.02	561	350	13	8	549	5	547	5e-77	269
rs:WP_010846448	DNA topoisomerase [Xenorhabdus nematophila].	33.33	543	330	13	7	532	4	531	6e-77	269
rs:WP_003289344	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	32.33	566	336	17	8	549	5	547	6e-77	269
rs:WP_007372580	DNA topoisomerase III [Kosakonia radicincitans].	30.32	597	373	16	8	581	5	581	6e-77	269
rs:WP_039178370	DNA topoisomerase III [Halomonas hydrothermalis].	31.37	593	370	18	7	584	4	574	7e-77	269
rs:WP_029569410	DNA topoisomerase III [Pantoea ananatis].	31.77	554	343	13	7	540	4	542	7e-77	269
rs:WP_036566114	DNA topoisomerase III [Oceanospirillum beijerinckii].	31.93	548	347	12	8	539	5	542	8e-77	268
rs:WP_001764957	DNA topoisomerase III [Escherichia coli].	32.40	571	336	12	8	556	5	547	8e-77	269
rs:WP_003699926	DNA topoisomerase III [Neisseria gonorrhoeae].	32.49	551	345	13	7	539	4	545	1e-76	269
rs:WP_021564887	hypothetical protein [Escherichia coli].	30.80	578	363	13	8	563	5	567	1e-76	268
rs:WP_019105610	DNA topoisomerase III [Pantoea ananatis].	30.51	603	377	16	7	586	4	587	1e-76	268
rs:WP_021820845	DNA topoisomerase III [Halomonas sp. BJGMM-B45].	29.73	592	382	15	7	584	4	575	2e-76	267
rs:WP_008812062	DNA topoisomerase III [Burkholderiales bacterium 1_1_47].	34.22	561	328	15	8	541	5	551	2e-76	266
rs:WP_044321331	DNA topoisomerase III [Pseudomonas amygdali].	31.72	558	346	14	8	548	5	544	3e-76	267
rs:WP_014606859	DNA topoisomerase III [Pantoea ananatis].	30.78	601	378	16	7	586	4	587	3e-76	267
rs:WP_003693191	DNA topoisomerase 3 [Neisseria gonorrhoeae].	32.30	551	346	13	7	539	4	545	3e-76	267
rs:WP_030072583	DNA topoisomerase III [Halomonas alkaliantarctica].	30.34	590	381	17	7	584	4	575	3e-76	266
rs:WP_003286333	DNA topoisomerase III [Pseudomonas stutzeri].	32.33	566	347	13	1	548	1	548	4e-76	266
rs:WP_003695219	DNA topoisomerase III [Neisseria gonorrhoeae].	32.30	551	346	13	7	539	4	545	4e-76	267
rs:WP_044143441	hypothetical protein, partial [Succinimonas amylolytica].	30.97	578	338	16	3	534	2	564	4e-76	267
rs:WP_038485011	DNA topoisomerase III [Halomonas campaniensis].	30.22	589	383	16	7	584	4	575	4e-76	266
rs:WP_007159931	DNA topoisomerase III [Pseudomonas psychrotolerans].	31.60	557	349	13	8	548	5	545	5e-76	266
tr:F2B8G7_9NEIS	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.36	558	349	13	7	539	4	552	9e-76	265
rs:WP_038141933	DNA topoisomerase III [Thiothrix lacustris].	30.86	580	363	13	8	559	4	573	9e-76	266
rs:WP_018915941	DNA topoisomerase III [Halomonas zhanjiangensis].	30.05	589	384	16	7	584	4	575	9e-76	265
rs:WP_028724189	DNA topoisomerase III [Pantoea ananatis].	31.34	552	348	12	7	540	4	542	9e-76	266
rs:WP_035470059	DNA topoisomerase III, partial [Gammaproteobacteria bacterium MFB021].	30.27	598	382	19	7	590	4	580	1e-75	265
rs:WP_015701195	DNA topoisomerase III [Pantoea ananatis].	30.62	552	352	12	7	540	4	542	1e-75	266
rs:WP_027335540	DNA topoisomerase III [Halomonas sp. HL-48].	31.02	590	377	17	7	584	4	575	2e-75	264
rs:WP_026971115	DNA topoisomerase III [Aliagarivorans marinus].	31.71	615	374	20	8	595	5	600	2e-75	265
rs:WP_010370844	DNA topoisomerase III [Pseudoalteromonas piscicida].	33.76	542	327	14	8	531	5	532	2e-75	264
rs:WP_035015800	DNA topoisomerase III [Catenovulum agarivorans].	31.86	587	355	15	8	562	5	578	2e-75	265
tr:S6U3B9_PSESF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.40	551	341	13	18	549	3	535	2e-75	265
rs:WP_021014746	DNA topoisomerase III [Serratia sp. ATCC 39006].	32.20	559	348	13	7	549	4	547	3e-75	265
rs:WP_039338988	DNA topoisomerase III [Pantoea stewartii].	30.98	552	350	11	7	540	4	542	3e-75	265
rs:WP_009724609	DNA topoisomerase III [Halomonas sp. TD01].	30.22	589	383	16	7	584	4	575	3e-75	264
tr:L9UC23_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.92	595	389	16	1	584	26	603	3e-75	265
rs:WP_025240834	DNA topoisomerase III [Pseudomonas stutzeri].	32.68	563	338	16	7	548	4	546	3e-75	264
rs:WP_039858283	DNA topoisomerase III [Halomonas titanicae].	30.22	589	383	16	7	584	4	575	3e-75	264
rs:WP_022523733	DNA topoisomerase III [Halomonas sp. A3H3].	30.22	589	383	16	7	584	4	575	3e-75	264
rs:WP_035815289	hypothetical protein, partial [Cupriavidus basilensis].	31.48	559	346	15	8	544	5	548	4e-75	264
rs:WP_035578786	DNA topoisomerase III [Halomonas sp. TG39a].	30.96	591	376	18	7	584	4	575	4e-75	264
rs:WP_033910510	DNA topoisomerase III [Neisseria gonorrhoeae].	32.12	551	347	13	7	539	4	545	4e-75	264
rs:WP_046360976	hypothetical protein, partial [Hafnia alvei].	31.69	587	368	15	15	582	2	574	5e-75	263
rs:WP_044628054	DNA topoisomerase III [Halomonas meridiana].	29.83	590	384	17	7	584	4	575	6e-75	263
rs:WP_016488058	DNA topoisomerase III [Pseudomonas putida].	31.70	552	345	13	8	544	5	539	7e-75	263
rs:WP_044175018	DNA topoisomerase III [Photobacterium damselae].	31.63	569	353	15	8	553	5	560	7e-75	263
rs:WP_040477989	DNA topoisomerase III, partial [Halomonas smyrnensis].	30.02	593	381	15	7	585	4	576	7e-75	263
rs:WP_038161991	DNA topoisomerase III [Trabulsiella guamensis].	30.07	562	363	12	7	553	4	550	7e-75	263
rs:WP_046005476	DNA topoisomerase III [Pseudoalteromonas rubra].	30.71	609	393	15	8	602	5	598	8e-75	263
rs:WP_025460229	DNA topoisomerase III [Neisseria meningitidis].	32.26	558	350	14	7	546	4	551	8e-75	263
rs:WP_013972307	DNA topoisomerase III [Pseudomonas putida].	31.34	552	348	12	8	544	5	540	9e-75	263
tr:I3BZ80_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.05	570	362	11	2	549	10	570	1e-74	262
rs:WP_041158384	DNA topoisomerase III [Halomonas sp. KHS3].	30.05	589	384	16	7	584	4	575	1e-74	262
rs:WP_006646506	DNA topoisomerase III [Photobacterium sp. SKA34].	31.63	569	353	15	8	553	5	560	2e-74	262
tr:A0A0D6EA40_9GAMM	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:CEP36445.1};	30.80	591	377	18	7	584	4	575	2e-74	262
rs:WP_023931617	DNA topoisomerase III [Photobacterium leiognathi].	31.63	569	353	15	8	553	5	560	2e-74	262
rs:WP_039492215	DNA topoisomerase III [Pseudoalteromonas elyakovii].	33.21	542	330	13	8	531	5	532	2e-74	262
rs:WP_040241684	DNA topoisomerase III [Chromohalobacter japonicus].	29.17	593	395	16	7	590	4	580	2e-74	261
rs:WP_040841233	DNA topoisomerase III, partial [Thiothrix nivea].	31.21	564	357	11	8	549	5	559	2e-74	261
rs:WP_019935838	DNA topoisomerase III [Oceanimonas smirnovii].	30.35	570	365	14	8	557	5	562	2e-74	261
rs:WP_036813091	DNA topoisomerase III [Photorhabdus luminescens].	33.45	556	326	15	8	537	5	542	3e-74	263
rs:WP_042147566	DNA topoisomerase III [Pseudoalteromonas sp. '520P1 No. 412'].	32.97	552	326	14	8	531	5	540	3e-74	261
rs:WP_045039898	DNA topoisomerase III [Photobacterium iliopiscarium].	31.81	569	352	15	8	553	5	560	3e-74	261
rs:WP_016954622	DNA topoisomerase III [Catenovulum agarivorans].	31.97	588	354	15	8	562	5	579	3e-74	262
rs:WP_008956693	DNA topoisomerase III [Halomonas sp. HAL1].	30.92	595	371	18	7	584	4	575	4e-74	261
rs:WP_016402350	DNA topoisomerase III [Agarivorans albus].	29.64	614	397	17	8	603	5	601	5e-74	261
rs:WP_017217778	DNA topoisomerase III [Pseudoalteromonas sp. NJ631].	33.21	542	330	13	8	531	5	532	5e-74	261
rs:WP_025732981	DNA topoisomerase III [Carnimonas nigrificans].	29.95	561	362	13	7	549	4	551	5e-74	261
rs:WP_018692714	hypothetical protein [Algicola sagamiensis].	31.94	573	344	19	7	553	4	556	6e-74	260
rs:WP_007114003	DNA topoisomerase III [Halomonas boliviensis].	30.05	589	384	16	7	584	4	575	6e-74	260
rs:WP_010607879	DNA topoisomerase III [Pseudoalteromonas flavipulchra].	33.03	542	331	13	8	531	5	532	7e-74	260
rs:WP_044342514	DNA topoisomerase III [Pseudomonas oryzihabitans].	31.42	557	350	13	8	548	5	545	8e-74	260
rs:WP_028685751	DNA topoisomerase III [Phaseolibacter flectens].	30.00	570	367	14	8	557	5	562	9e-74	260
rs:WP_017642366	DNA topoisomerase III [Pseudomonas sp. 313].	31.18	558	350	14	8	548	5	545	9e-74	260
rs:WP_027597366	DNA topoisomerase III [Pseudomonas sp. MOIL14HWK12:I2].	31.42	557	350	13	8	548	5	545	1e-73	260
rs:WP_042134694	DNA topoisomerase III [Pseudomonas oryzihabitans].	31.42	557	350	13	8	548	5	545	1e-73	260
rs:WP_035477107	DNA topoisomerase III [Aliagarivorans taiwanensis].	31.29	620	375	20	8	595	5	605	1e-73	260
rs:WP_035596778	DNA topoisomerase III [Halomonas salina].	29.85	593	382	15	7	585	4	576	1e-73	260
rs:WP_044593054	DNA topoisomerase III, partial [Salmonella enterica].	33.27	556	327	15	8	537	5	542	2e-73	258
rs:WP_006356165	DNA topoisomerase III [[Clostridium] methylpentosum].	32.52	618	343	26	1	590	1	572	2e-73	261
rs:WP_045989685	DNA topoisomerase III [Pseudoalteromonas piscicida].	33.03	542	331	13	8	531	5	532	3e-73	258
tr:N2ILA1_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.41	630	399	16	3	601	2	610	3e-73	260
rs:WP_043170626	MULTISPECIES: DNA topoisomerase III [Aeromonas].	29.94	618	389	18	7	602	4	599	3e-73	259
rs:WP_019821571	DNA topoisomerase III [Vibrio splendidus].	32.33	563	326	17	4	539	1	535	3e-73	260
rs:WP_021598073	DNA topoisomerase III protein TopB [Escherichia coli].	33.21	563	332	15	8	544	5	549	4e-73	260
rs:WP_040536140	hypothetical protein, partial [Legionella drancourtii].	32.62	515	312	14	41	535	1	500	5e-73	258
rs:WP_039159053	DNA topoisomerase III [Gallibacterium anatis].	28.98	628	395	19	7	603	4	611	5e-73	258
rs:WP_034934415	DNA topoisomerase III [Erwinia mallotivora].	28.95	563	369	12	7	553	4	551	5e-73	258
rs:WP_031592645	DNA topoisomerase III [Pantoea agglomerans].	30.67	551	351	12	7	539	4	541	5e-73	258
rs:WP_038059221	hypothetical protein, partial [Thiobacillus denitrificans].	31.60	519	316	16	41	531	1	508	5e-73	258
rs:WP_035565951	DNA topoisomerase III [Halomonas sp. KO116].	30.80	591	377	17	7	584	4	575	6e-73	258
rs:WP_039090578	DNA topoisomerase III [Gallibacterium anatis].	30.70	570	352	16	7	548	4	558	6e-73	258
rs:WP_008374266	DNA topoisomerase III [Pseudomonas sp. M47T1].	31.36	558	346	15	8	547	5	543	6e-73	258
rs:WP_024599846	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	30.81	568	359	14	8	553	5	560	7e-73	258
rs:WP_040289620	DNA topoisomerase III, partial [Bilophila wadsworthia].	32.68	560	337	17	7	548	4	541	9e-73	257
rs:WP_044423469	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	31.57	529	327	12	8	517	5	517	1e-72	254
rs:WP_035889396	DNA topoisomerase III [Kosakonia radicincitans].	31.56	564	350	13	8	553	5	550	1e-72	258
rs:WP_037031292	DNA topoisomerase III [Pseudomonas sp. HPB0071].	28.48	625	395	16	8	601	5	608	1e-72	259
tr:F3QN10_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.28	567	348	15	3	548	2	553	1e-72	256
rs:WP_020680308	DNA topoisomerase III [Marinobacterium rhizophilum].	31.79	560	349	15	8	548	5	550	1e-72	257
rs:WP_017785618	DNA topoisomerase III [Aeromonas hydrophila].	29.77	618	390	18	7	602	4	599	1e-72	257
rs:WP_032438011	DNA topoisomerase III [Klebsiella pneumoniae].	33.45	556	326	15	8	537	5	542	2e-72	258
rs:WP_041454535	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	30.92	566	359	13	8	553	5	558	2e-72	256
rs:WP_040465856	DNA topoisomerase III, partial [Erwinia tracheiphila].	28.93	560	363	14	7	548	4	546	2e-72	254
rs:WP_046519398	DNA topoisomerase III [Rheinheimera sp. IITR-13].	30.00	570	358	13	8	553	5	557	2e-72	256
rs:WP_039165985	DNA topoisomerase III [Gallibacterium anatis].	30.53	570	353	16	7	548	4	558	2e-72	256
rs:WP_005306353	MULTISPECIES: DNA topoisomerase III [Aeromonas].	29.77	618	390	18	7	602	4	599	3e-72	256
tr:R9NHH5_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.93	560	363	14	7	548	4	546	3e-72	254
rs:WP_027600619	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	31.24	557	351	13	8	548	5	545	3e-72	256
rs:WP_043775642	DNA topoisomerase III, partial [Desulfomicrobium escambiense].	31.78	557	352	12	5	553	4	540	3e-72	254
rs:WP_024126915	hypothetical protein [Vibrio cholerae].	33.27	556	327	15	8	537	5	542	3e-72	258
rs:WP_000366821	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	33.27	556	327	15	8	537	5	542	3e-72	258
rs:WP_021724503	DNA topoisomerase III [Avibacterium paragallinarum].	29.68	620	374	22	7	593	4	594	4e-72	256
rs:WP_000366822	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	33.27	556	327	15	8	537	5	542	4e-72	257
rs:WP_036793769	DNA topoisomerase III [Photobacterium phosphoreum].	31.28	617	378	18	8	598	5	601	4e-72	255
rs:WP_022542388	DNA topoisomerase III [Salmonella enterica].	33.27	556	327	15	8	537	5	542	4e-72	257
rs:WP_039161879	DNA topoisomerase III [Gallibacterium anatis].	30.24	572	352	17	7	548	4	558	4e-72	255
rs:WP_017409798	DNA topoisomerase III [Aeromonas hydrophila].	29.66	617	391	18	7	602	4	598	5e-72	256
rs:WP_011872847	DNA topoisomerase III [Yersinia ruckeri].	33.45	556	326	16	8	537	5	542	5e-72	257
rs:WP_040603635	DNA topoisomerase [Parasutterella excrementihominis].	32.16	566	348	15	4	548	1	551	5e-72	254
rs:WP_034164950	DNA topoisomerase III [Edwardsiella tarda].	32.44	558	341	15	8	543	5	548	5e-72	257
rs:WP_035379522	DNA topoisomerase III, partial [Fervidicella metallireducens].	33.87	561	322	21	7	550	6	534	5e-72	254
rs:WP_036966356	DNA topoisomerase III [Pseudoalteromonas lipolytica].	32.50	557	346	16	8	548	5	547	5e-72	255
rs:WP_000366823	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	33.27	556	327	15	8	537	5	542	6e-72	257
rs:WP_026003740	DNA topoisomerase III [Pseudomonas luteola].	28.16	625	397	16	8	601	5	608	7e-72	257
rs:WP_042852207	DNA topoisomerase III [Escherichia coli].	33.27	556	327	15	8	537	5	542	7e-72	256
rs:WP_033965820	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	32.65	487	297	9	87	552	1	477	7e-72	254
rs:WP_036845149	DNA topoisomerase III [Photorhabdus temperata].	33.27	556	327	15	8	537	5	542	7e-72	256
rs:WP_008540190	DNA topoisomerase III [Megamonas funiformis].	31.77	554	345	17	4	550	1	528	7e-72	256
rs:WP_024942122	DNA topoisomerase III [Aeromonas hydrophila].	29.61	618	391	18	7	602	4	599	8e-72	255
rs:WP_042870441	DNA topoisomerase III [Aeromonas piscicola].	29.66	617	393	16	7	602	4	600	9e-72	255
rs:WP_013141536	DNA topoisomerase III [Xenorhabdus nematophila].	33.27	556	327	15	8	537	5	542	1e-71	256
rs:WP_026052510	DNA topoisomerase III [Gayadomonas joobiniege].	31.93	570	359	14	8	559	5	563	1e-71	254
rs:WP_005709182	DNA topoisomerase III [Haemophilus paraphrohaemolyticus].	31.06	573	362	17	7	559	4	563	1e-71	254
rs:WP_021461897	DNA topoisomerase III [Gallibacterium anatis].	30.77	572	349	17	7	548	4	558	1e-71	254
rs:WP_046079688	DNA topoisomerase III [Halomonas sp. HG01].	29.12	594	385	15	7	585	4	576	1e-71	254
rs:WP_000366819	DNA topoisomerase III [Vibrio mimicus].	33.09	556	328	15	8	537	5	542	1e-71	256
rs:WP_033135309	DNA topoisomerase III [Aeromonas sp. 4287D].	29.98	617	389	18	7	601	4	599	1e-71	254
rs:WP_013332057	DNA topoisomerase III [Halomonas elongata].	30.36	550	361	13	7	549	4	538	1e-71	254
rs:WP_025202529	DNA topoisomerase III [Aeromonas hydrophila].	29.61	618	391	18	7	602	4	599	2e-71	254
rs:WP_039095869	DNA topoisomerase III [Gallibacterium anatis].	29.05	630	392	20	7	603	4	611	2e-71	254
rs:WP_004072118	DNA topoisomerase III [Desulfobacter postgatei].	30.13	604	385	17	7	596	4	584	2e-71	255
rs:WP_039147192	DNA topoisomerase III [Gallibacterium anatis].	30.18	570	355	16	7	548	4	558	2e-71	254
rs:WP_020586452	DNA topoisomerase III [Desulfobacter curvatus].	29.70	606	387	18	7	597	4	585	2e-71	255
rs:WP_017787114	DNA topoisomerase III [Aeromonas hydrophila].	29.61	618	391	18	7	602	4	599	2e-71	254
rs:WP_035685029	DNA topoisomerase III [Avibacterium paragallinarum].	29.55	616	380	21	7	593	4	594	2e-71	254
tr:A0A099MYA2_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.90	547	347	13	8	539	5	535	2e-71	254
rs:WP_008897065	DNA topoisomerase III [Rheinheimera sp. A13L].	30.59	572	354	15	7	553	4	557	2e-71	254
rs:WP_042005726	DNA topoisomerase III [Aeromonas dhakensis].	31.14	562	351	15	7	549	4	548	2e-71	254
rs:WP_010635840	DNA topoisomerase III [Aeromonas dhakensis].	29.61	618	391	18	7	602	4	599	2e-71	254
rs:WP_042337355	hypothetical protein [Burkholderia ferrariae].	30.00	630	394	17	8	603	5	621	3e-71	254
rs:WP_042063818	DNA topoisomerase III [Aeromonas allosaccharophila].	29.94	618	390	17	7	602	4	600	3e-71	254
rs:WP_046553465	DNA topoisomerase III [Arsukibacterium sp. MJ3].	30.99	568	354	14	8	549	5	560	3e-71	254
rs:WP_016414676	DNA topoisomerase III [Halomonas anticariensis].	28.79	594	381	14	7	582	4	573	3e-71	253
rs:WP_024894057	DNA topoisomerase III [Acidithiobacillus thiooxidans].	32.16	566	324	15	7	548	4	533	3e-71	253
rs:WP_045336885	hypothetical protein [Enterobacter asburiae].	30.43	608	380	16	1	582	1	591	3e-71	254
rs:WP_042050123	DNA topoisomerase III [Aeromonas dhakensis].	29.61	618	391	18	7	602	4	599	3e-71	253
rs:WP_005705826	DNA topoisomerase III [Haemophilus parahaemolyticus].	30.89	573	363	17	7	559	4	563	4e-71	253
rs:WP_039092690	DNA topoisomerase III [Gallibacterium anatis].	28.98	628	395	19	7	603	4	611	4e-71	253
rs:WP_022943541	DNA topoisomerase III [Pseudoalteromonas ruthenica].	31.06	557	353	16	8	548	5	546	4e-71	253
rs:WP_028470948	DNA topoisomerase III [Neptunomonas japonica].	31.02	577	359	14	8	557	5	569	4e-71	253
rs:WP_021231452	DNA topoisomerase III [Aeromonas veronii].	29.94	618	390	18	7	602	4	600	4e-71	253
rs:WP_009838492	DNA topoisomerase III [Pseudoalteromonas tunicata].	30.18	603	387	16	8	593	5	590	4e-71	253
tr:W1W148_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.06	574	345	16	5	559	3	550	4e-71	254
rs:WP_013184415	DNA topoisomerase III [Xenorhabdus nematophila].	33.09	556	328	15	8	537	5	542	4e-71	254
rs:WP_046557200	DNA topoisomerase III [Arsukibacterium ikkense].	28.84	638	396	19	8	607	5	622	4e-71	253
rs:WP_010944885	DNA topoisomerase III [Haemophilus ducreyi].	34.36	454	276	9	8	452	5	445	5e-71	249
rs:WP_029304903	DNA topoisomerase III [Aeromonas hydrophila].	29.61	618	391	18	7	602	4	599	5e-71	253
rs:WP_039151066	DNA topoisomerase III [Gallibacterium anatis].	29.14	628	394	19	7	603	4	611	5e-71	253
rs:WP_010628045	DNA topoisomerase III [Halomonas sp. KM-1].	29.01	586	394	13	7	584	4	575	5e-71	253
rs:WP_010845928	DNA topoisomerase [Xenorhabdus nematophila].	32.91	556	329	15	8	537	5	542	5e-71	254
tr:Q3II06_PSEHT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.83	545	347	12	29	553	7	541	5e-71	252
rs:WP_017110286	DNA topoisomerase III [Vibrio tasmaniensis].	32.21	562	328	18	4	539	1	535	6e-71	254
rs:WP_004072223	DNA topoisomerase III [Desulfobacter postgatei].	30.36	606	383	18	7	597	4	585	6e-71	254
rs:WP_045980530	DNA topoisomerase III [Pseudoalteromonas ruthenica].	30.63	555	358	14	8	548	5	546	6e-71	252
tr:A0A017RV88_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	33.87	561	322	21	7	550	6	534	6e-71	254
rs:WP_039084901	DNA topoisomerase III [Gallibacterium anatis].	30.35	570	354	16	7	548	4	558	6e-71	252
rs:WP_007524702	DNA topoisomerase III [Haemophilus sputorum].	28.71	613	392	16	7	602	4	588	6e-71	252
rs:WP_016352275	DNA topoisomerase III [Aeromonas hydrophila].	29.45	618	392	18	7	602	4	599	6e-71	253
rs:WP_027849899	DNA topoisomerase III [Marinospirillum insulare].	30.48	561	358	14	8	548	5	553	6e-71	252
rs:WP_043153916	DNA topoisomerase III [Aeromonas sp. HZM].	29.98	617	390	18	7	602	4	599	7e-71	253
rs:WP_039168663	DNA topoisomerase III [Gallibacterium anatis].	29.14	628	394	19	7	603	4	611	7e-71	252
tr:E5Y702_BILWA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.68	560	337	17	7	548	4	541	7e-71	254
rs:WP_042657288	DNA topoisomerase III [Aeromonas allosaccharophila].	30.02	613	390	17	7	597	4	599	7e-71	252
tr:A0A088SE88_SALCE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AIO10315.2};	33.27	556	327	16	8	537	5	542	7e-71	254
rs:WP_039636260	DNA topoisomerase III [Clostridium argentinense].	30.73	576	356	15	1	559	1	550	8e-71	254
rs:WP_010454695	DNA topoisomerase III [Succinivibrionaceae bacterium WG-1].	31.27	566	348	16	8	548	7	556	8e-71	254
rs:WP_010128333	DNA topoisomerase III [Haemophilus sputorum].	29.77	561	362	15	7	549	4	550	8e-71	252
rs:WP_042064235	DNA topoisomerase III [Aeromonas hydrophila].	29.66	617	392	17	7	602	4	599	9e-71	252
rs:WP_045048080	DNA topoisomerase III [Rouxiella chamberiensis].	30.72	573	359	18	8	557	5	562	9e-71	252
rs:WP_011507443	DNA topoisomerase III [Chromohalobacter salexigens].	28.81	590	395	16	7	586	4	578	9e-71	252
rs:WP_043165453	DNA topoisomerase III [Aeromonas hydrophila].	29.13	618	394	18	7	602	4	599	9e-71	252
tr:V8L219_XYLFS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.87	499	312	8	68	552	9	498	1e-70	251
rs:WP_043160134	DNA topoisomerase III [Aeromonas hydrophila].	29.45	618	392	18	7	602	4	599	1e-70	252
rs:WP_017781182	DNA topoisomerase III [Aeromonas hydrophila].	30.96	562	352	15	7	549	4	548	1e-70	251
rs:WP_017779312	DNA topoisomerase III [Aeromonas hydrophila].	29.45	618	392	18	7	602	4	599	1e-70	251
rs:WP_041216786	DNA topoisomerase III [Aeromonas hydrophila].	29.45	618	392	18	7	602	4	599	1e-70	251
rs:WP_029308519	DNA topoisomerase [Cupriavidus metallidurans].	29.33	583	363	13	8	547	5	581	1e-70	253
rs:WP_039086821	DNA topoisomerase III [Gallibacterium anatis].	30.18	570	355	16	7	548	4	558	1e-70	251
rs:WP_040404641	DNA topoisomerase III, partial [Amphritea japonica].	31.56	564	351	17	8	553	5	551	1e-70	250
rs:WP_005567881	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	31.06	586	353	22	7	559	4	571	2e-70	251
rs:WP_045788841	DNA topoisomerase III [Aeromonas hydrophila].	29.29	618	393	18	7	602	4	599	2e-70	251
rs:WP_012766322	MULTISPECIES: DNA topoisomerase 3 (DNA topoisomerase III) [Gammaproteobacteria].	32.68	557	329	16	8	537	5	542	2e-70	253
rs:WP_041982760	DNA topoisomerase III [Xenorhabdus nematophila].	32.22	537	339	9	8	530	5	530	2e-70	252
rs:WP_019951680	DNA topoisomerase III [Kushneria aurantia].	30.04	556	359	14	7	548	4	543	2e-70	251
rs:WP_024945198	DNA topoisomerase III [Aeromonas hydrophila].	29.29	618	393	18	7	602	4	599	2e-70	251
rs:WP_035241401	DNA topoisomerase III [Desulfobacter vibrioformis].	29.92	605	387	17	7	597	4	585	2e-70	253
rs:WP_039272426	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	32.68	557	329	16	8	537	5	542	2e-70	253
rs:WP_025235882	DNA topoisomerase III [Mannheimia varigena].	29.06	616	397	17	7	601	4	600	2e-70	251
rs:WP_043125882	DNA topoisomerase III [Aeromonas hydrophila].	29.13	618	394	18	7	602	4	599	2e-70	251
rs:WP_040292887	DNA topoisomerase, partial [Acetonema longum].	31.03	580	351	17	8	559	5	563	2e-70	251
rs:WP_000366824	DNA topoisomerase III [Salmonella enterica].	32.14	557	332	15	8	537	5	542	2e-70	252
rs:WP_006717380	DNA topoisomerase III [Aggregatibacter segnis].	30.85	590	357	21	7	563	4	575	3e-70	250
rs:WP_043142638	DNA topoisomerase III [Aeromonas salmonicida].	29.61	618	392	17	7	602	4	600	3e-70	251
rs:WP_005760640	DNA topoisomerase III [Pasteurella bettyae].	30.33	577	360	17	8	559	5	564	3e-70	250
rs:WP_014167642	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	31.06	586	353	22	7	559	4	571	3e-70	250
rs:WP_005566047	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	30.89	586	354	21	7	559	4	571	3e-70	250
rs:WP_043554278	DNA topoisomerase III [Aeromonas bestiarum].	29.61	618	392	17	7	602	4	600	3e-70	251
rs:WP_042036004	DNA topoisomerase III [Aeromonas popoffii].	29.66	617	392	17	7	602	4	599	3e-70	251
rs:WP_038220216	DNA topoisomerase III [Xenorhabdus nematophila].	33.09	556	328	15	8	537	5	542	3e-70	252
rs:WP_041154757	DNA topoisomerase III [Vibrio mytili].	30.36	560	342	12	8	539	5	544	3e-70	252
rs:WP_025342567	DNA topoisomerase III [Mannheimia varigena].	29.77	618	390	19	7	601	4	600	3e-70	250
rs:WP_041214278	DNA topoisomerase III [Aeromonas caviae].	29.82	617	391	18	7	602	4	599	3e-70	251
rs:WP_025247771	DNA topoisomerase III [Mannheimia varigena].	29.77	618	390	19	7	601	4	600	4e-70	250
rs:WP_023004588	DNA topoisomerase III [Halomonas sp. PBN3].	29.06	585	391	15	7	582	4	573	4e-70	250
rs:WP_017764797	DNA topoisomerase III [Aeromonas hydrophila].	29.77	618	390	18	7	602	4	599	4e-70	250
rs:WP_005577855	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	30.53	583	360	19	7	559	4	571	4e-70	250
rs:WP_039212971	DNA topoisomerase III [Aeromonas hydrophila].	29.45	618	392	18	7	602	4	599	4e-70	250
rs:WP_005542694	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	30.89	586	354	21	7	559	4	571	5e-70	250
tr:C3AGX8_BACMY	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.91	564	336	18	5	548	4	539	5e-70	249
tr:X2JT78_AGGAC	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.06	586	353	22	7	559	19	586	5e-70	250
rs:WP_029302276	DNA topoisomerase III [Aeromonas hydrophila].	29.13	618	394	18	7	602	4	599	5e-70	250
rs:WP_035412123	DNA topoisomerase III [Chromohalobacter israelensis].	27.89	588	403	13	7	586	4	578	6e-70	250
rs:WP_028762193	DNA topoisomerase III [Shewanella colwelliana].	29.76	615	383	20	8	593	5	599	6e-70	250
rs:WP_039977192	DNA topoisomerase III [Vibrio jasicida].	31.49	597	356	18	7	574	4	576	6e-70	251
rs:WP_041982297	DNA topoisomerase III [Xenorhabdus nematophila].	32.73	556	330	15	8	537	5	542	6e-70	251
rs:WP_014386700	MULTISPECIES: DNA topoisomerase III [Vibrionaceae].	30.36	560	342	12	8	539	5	544	7e-70	251
rs:WP_031762110	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	33.27	490	293	11	87	552	3	482	7e-70	248
rs:WP_006789974	DNA topoisomerase [Anaeroglobus geminatus].	30.22	599	378	14	4	580	1	581	7e-70	251
rs:WP_042907580	DNA topoisomerase III [Gallibacterium anatis].	30.18	570	355	16	7	548	4	558	7e-70	249
rs:WP_037592209	DNA topoisomerase, partial [Sporomusa ovata].	30.62	578	355	14	8	559	5	562	8e-70	249
rs:WP_046224208	DNA topoisomerase III [Vibrio sp. ECSMB14106].	30.36	560	342	12	8	539	5	544	8e-70	251
rs:WP_031383673	DNA topoisomerase III [Halomonas zincidurans].	28.52	589	393	15	7	584	4	575	8e-70	249
rs:WP_039038404	DNA topoisomerase III [Pseudoalteromonas sp. ECSMB14103].	32.53	538	339	12	8	531	5	532	9e-70	249
rs:WP_013745451	DNA topoisomerase III [Gallibacterium anatis].	30.59	572	350	17	7	548	4	558	9e-70	249
rs:WP_025822161	DNA topoisomerase III [Shewanella marina].	31.68	565	348	16	8	548	5	555	1e-69	249
tr:F7NGY8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.03	580	351	17	8	559	5	563	1e-69	251
rs:WP_019442553	DNA topoisomerase III [Moritella marina].	31.75	548	340	14	8	531	5	542	1e-69	249
rs:WP_032092263	DNA topoisomerase III [Necropsobacter rosorum].	29.73	619	384	21	4	595	1	595	1e-69	249
rs:WP_040095505	DNA topoisomerase III [Aeromonas australiensis].	29.61	618	392	18	7	602	4	600	1e-69	249
rs:WP_045525843	DNA topoisomerase III [Aeromonas hydrophila].	29.45	618	392	18	7	602	4	599	1e-69	249
rs:WP_026592563	DNA topoisomerase III [Bacillus sp. UNC437CL72CviS29].	32.16	566	332	18	5	548	4	539	1e-69	251
rs:WP_010390952	DNA topoisomerase III [Pseudoalteromonas undina].	32.10	539	340	13	8	531	5	532	1e-69	249
tr:T0JN21_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.62	578	355	14	8	559	5	562	1e-69	249
rs:WP_040264327	DNA topoisomerase III [Serratia symbiotica].	29.87	596	377	15	8	581	5	581	1e-69	249
tr:A0A0A5MQ36_AERCA	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.82	617	391	18	7	602	4	599	1e-69	249
gp:CP003909_766	DNA topoisomerase III [Neisseria gonorrhoeae MS11]	31.49	524	334	12	34	539	12	528	1e-69	249
rs:WP_044801014	DNA topoisomerase III [Aeromonas hydrophila].	29.13	618	394	18	7	602	4	599	1e-69	249
rs:WP_042016249	DNA topoisomerase III [Aeromonas caviae].	29.66	617	392	18	7	602	4	599	1e-69	249
rs:WP_045522780	DNA topoisomerase III [Aeromonas caviae].	29.82	617	391	18	7	602	4	599	1e-69	249
rs:WP_035209415	DNA topoisomerase III [Acidithiobacillus thiooxidans].	30.62	565	338	13	5	548	3	534	1e-69	250
rs:WP_022965391	DNA topoisomerase III [Pseudomonas caeni].	30.37	573	361	16	8	557	5	562	1e-69	248
rs:WP_019018703	DNA topoisomerase III [Halomonas lutea].	28.76	598	380	16	7	584	4	575	1e-69	249
rs:WP_042864792	DNA topoisomerase III [Aeromonas hydrophila].	29.66	617	392	18	7	602	4	599	1e-69	249
rs:WP_036191270	DNA topoisomerase III [Marinobacterium sp. AK27].	30.45	555	361	13	8	549	5	547	1e-69	249
rs:WP_005546712	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	31.06	586	353	22	7	559	4	571	1e-69	248
rs:WP_014029288	DNA topoisomerase III [Acidithiobacillus ferrivorans].	31.35	555	322	15	7	537	4	523	2e-69	248
rs:WP_025217413	DNA topoisomerase III [Mannheimia varigena].	29.77	618	390	19	7	601	4	600	2e-69	248
rs:WP_039137280	DNA topoisomerase III [Gallibacterium genomosp. 2].	30.00	570	356	16	7	548	4	558	2e-69	248
rs:WP_039041035	DNA topoisomerase III [Aeromonas caviae].	29.66	617	392	18	7	602	4	599	2e-69	249
rs:WP_039032788	DNA topoisomerase III [Shewanella sp. ECSMB14102].	30.18	560	360	14	8	548	5	552	2e-69	249
rs:WP_008132140	DNA topoisomerase III [Pseudoalteromonas sp. BSi20480].	32.53	538	339	12	8	531	5	532	2e-69	248
rs:WP_006794257	DNA topoisomerase III [Alteromonadales bacterium TW-7].	32.53	538	339	12	8	531	5	532	2e-69	248
rs:WP_039660108	DNA topoisomerase III [Pantoea sp. MBLJ3].	30.49	574	359	19	8	557	5	562	2e-69	248
rs:WP_041211922	DNA topoisomerase III [Aeromonas caviae].	29.66	617	392	18	7	602	4	599	2e-69	249
tr:A0A059ZW14_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.78	549	327	12	5	531	3	520	2e-69	251
rs:WP_039335056	hypothetical protein, partial [Burkholderia multivorans].	29.70	633	395	18	8	603	5	624	2e-69	249
rs:WP_010557793	DNA topoisomerase III [Pseudoalteromonas marina].	32.53	538	339	12	8	531	5	532	2e-69	248
tr:B3GXI1_ACTP7	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.79	574	374	15	4	559	8	570	2e-69	248
rs:WP_005617231	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	29.79	574	374	15	4	559	1	563	2e-69	248
rs:WP_028303988	DNA topoisomerase III [Oceanospirillum maris].	28.57	637	398	14	8	607	5	621	2e-69	248
rs:WP_045377142	hypothetical protein [Enterobacter aerogenes].	30.20	606	384	15	1	582	1	591	2e-69	249
rs:WP_042880354	DNA topoisomerase III [Aeromonas sp. ZOR0002].	29.66	617	392	18	7	602	4	599	2e-69	249
rs:WP_005600974	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	29.62	574	375	15	4	559	1	563	2e-69	248
rs:WP_027857709	DNA topoisomerase III [Marinobacterium jannaschii].	31.72	558	352	14	8	549	5	549	2e-69	248
rs:WP_033102640	MULTISPECIES: DNA topoisomerase III [Alteromonadales].	32.28	539	339	13	8	531	5	532	2e-69	248
rs:WP_028603717	hypothetical protein [Ottowia thiooxydans].	29.05	568	373	10	5	546	4	567	2e-69	248
rs:WP_001140204	DNA topoisomerase III [Bacillus cereus].	31.63	569	331	17	5	548	4	539	3e-69	249
rs:WP_027961016	DNA topoisomerase III [Halomonas halodenitrificans].	29.45	584	386	15	7	580	4	571	3e-69	248
tr:A3N0A8_ACTP2	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.79	574	374	15	4	559	8	570	3e-69	248
rs:WP_010675967	DNA topoisomerase III [Aeromonas caviae].	29.66	617	392	18	7	602	4	599	3e-69	248
rs:WP_042981626	DNA topoisomerase III [Bacillus mycoides].	32.86	566	328	19	5	548	4	539	3e-69	249
rs:WP_034617905	DNA topoisomerase III [Chelonobacter oris].	29.41	578	366	17	7	559	4	564	3e-69	248
rs:WP_011468024	DNA topoisomerase III [Saccharophagus degradans].	31.58	570	345	17	8	548	5	558	3e-69	248
rs:WP_040216197	DNA topoisomerase III [Haemophilus parahaemolyticus].	30.24	572	366	17	8	559	5	563	3e-69	248
rs:WP_034639106	DNA topoisomerase III [Bacillus manliponensis].	32.16	566	332	18	5	548	4	539	3e-69	249
rs:WP_032470230	DNA topoisomerase III [Vibrio cholerae].	30.58	569	352	15	8	548	5	558	3e-69	248
rs:WP_018346753	DNA topoisomerase III [Gallibacterium anatis].	30.65	571	351	17	7	548	4	558	3e-69	248
rs:WP_005607634	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	29.79	574	374	15	4	559	1	563	3e-69	247
rs:WP_046588404	DNA topoisomerase III [Bacillus sp. SA1-12].	31.91	564	336	17	5	548	4	539	3e-69	249
rs:WP_008110196	DNA topoisomerase III [Pseudoalteromonas sp. BSi20311].	32.28	539	339	13	8	531	5	532	4e-69	248
rs:WP_038643496	DNA topoisomerase III [Pantoea rwandensis].	28.62	594	387	14	8	581	5	581	4e-69	248
rs:WP_005552801	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	30.72	586	355	21	7	559	4	571	4e-69	248
rs:WP_033003857	DNA topoisomerase III, partial [Vibrio azureus].	32.68	560	340	15	4	548	1	538	4e-69	248
rs:WP_009875554	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	29.79	574	374	15	4	559	1	563	4e-69	247
rs:WP_045407416	DNA topoisomerase III [Vibrio jasicida].	31.87	568	340	16	7	549	4	549	4e-69	249
rs:WP_028115166	DNA topoisomerase III [Ferrimonas senticii].	30.22	556	359	13	8	548	6	547	4e-69	247
rs:WP_036979860	DNA topoisomerase III [Pseudoalteromonas sp. SCSIO_11900].	31.60	538	344	11	8	531	5	532	4e-69	247
rs:WP_013795485	DNA topoisomerase III [Marinomonas posidonica].	29.93	608	386	15	8	593	5	594	4e-69	247
rs:WP_005557593	DNA topoisomerase III [Aggregatibacter actinomycetemcomitans].	30.89	586	354	21	7	559	4	571	5e-69	247
rs:WP_039081471	DNA topoisomerase III [Gallibacterium anatis].	28.73	630	394	20	7	603	4	611	5e-69	247
rs:WP_017085213	DNA topoisomerase III [Vibrio splendidus].	30.58	556	346	11	8	539	5	544	5e-69	249
rs:WP_047234969	DNA topoisomerase III [Aeromonas hydrophila].	30.27	555	349	12	8	539	5	544	5e-69	249
rs:WP_033920949	DNA topoisomerase III [Listeria monocytogenes].	30.55	622	372	19	5	606	4	585	5e-69	248
rs:WP_040187403	DNA topoisomerase III [Halomonas salina].	27.94	587	401	14	7	585	4	576	5e-69	247
tr:E6QBD0_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CBI04506.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI04506.1};	32.61	555	334	16	8	539	6	543	5e-69	247
rs:WP_020311399	MULTISPECIES: DNA topoisomerase [Megasphaera].	30.93	569	351	16	7	552	4	553	5e-69	248
rs:WP_010786935	DNA topoisomerase III [Haemophilus parasuis].	28.46	615	390	15	8	602	5	589	6e-69	247
tr:F9ZNS5_ACICS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.33	549	324	13	5	531	3	520	6e-69	249
rs:WP_003722116	DNA topoisomerase III [Listeria monocytogenes].	30.55	622	372	19	5	606	4	585	6e-69	248
rs:WP_009353583	DNA topoisomerase, partial [Veillonella sp. oral taxon 780].	33.08	535	314	16	38	550	3	515	6e-69	248
rs:WP_009924395	DNA topoisomerase III [Listeria monocytogenes].	30.55	622	372	19	5	606	4	585	6e-69	248
rs:WP_014931756	DNA topoisomerase III [Listeria monocytogenes].	30.55	622	372	19	5	606	4	585	6e-69	248
rs:WP_028773045	DNA topoisomerase III [Shewanella waksmanii].	30.51	567	354	15	8	548	5	557	6e-69	247
rs:WP_005597148	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	29.62	574	375	15	4	559	1	563	7e-69	246
rs:WP_011899410	DNA topoisomerase III [Aeromonas salmonicida].	31.36	558	335	13	8	537	5	542	7e-69	248
rs:WP_012621725	DNA topoisomerase III [Haemophilus parasuis].	28.46	615	390	15	8	602	5	589	7e-69	246
tr:U3A8G4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.68	560	340	15	4	548	1	538	8e-69	248
rs:WP_017154075	DNA topoisomerase III [Bacillus sp. FJAT-13831].	31.99	569	329	18	5	548	4	539	8e-69	248
rs:WP_028834920	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	31.78	538	343	11	8	531	5	532	8e-69	246
rs:WP_039174200	DNA topoisomerase III [Gallibacterium genomosp. 1].	30.47	571	352	17	7	548	4	558	8e-69	246
rs:WP_045994243	DNA topoisomerase III [Halomonas sp. S2151].	30.20	586	379	15	7	580	4	571	9e-69	246
tr:F2LSE5_BURGS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.61	575	353	14	7	547	8	570	9e-69	248
rs:WP_011707714	DNA topoisomerase III [Aeromonas hydrophila].	29.61	618	392	17	7	602	4	600	9e-69	246
rs:WP_005604263	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	29.79	574	374	15	4	559	1	563	1e-68	246
rs:WP_025889512	DNA topoisomerase III [Shewanella haliotis].	30.36	560	359	14	8	548	5	552	1e-68	247
rs:WP_045700710	hypothetical protein, partial [Desulfobulbaceae bacterium BRH_c16a].	31.33	533	344	11	4	530	1	517	1e-68	246
rs:WP_027074724	DNA topoisomerase III [Mannheimia granulomatis].	29.06	616	397	17	7	601	4	600	1e-68	246
rs:WP_014601552	DNA topoisomerase III [Listeria monocytogenes].	30.55	622	372	19	5	606	4	585	1e-68	248
rs:WP_037319066	hypothetical protein, partial [Ruminobacter sp. RM87].	30.95	546	345	13	7	536	5	534	1e-68	245
rs:WP_010990062	DNA topoisomerase III [Listeria monocytogenes].	30.55	622	372	19	5	606	4	585	1e-68	248
rs:WP_012951084	DNA topoisomerase III [Listeria monocytogenes].	30.55	622	372	19	5	606	4	585	1e-68	248
rs:WP_037376986	DNA topoisomerase, partial [Selenomonas ruminantium].	30.00	540	349	13	8	531	5	531	1e-68	246
rs:WP_003732116	DNA topoisomerase III [Listeria monocytogenes].	30.39	622	373	19	5	606	4	585	1e-68	248
rs:WP_037364060	DNA topoisomerase, partial [Selenomonas ruminantium].	30.94	543	340	14	8	531	5	531	1e-68	246
rs:WP_031644988	DNA topoisomerase III [Listeria monocytogenes].	30.55	622	372	19	5	606	4	585	1e-68	248
rs:WP_024893297	DNA topoisomerase III [Acidithiobacillus thiooxidans].	31.87	524	325	10	43	548	39	548	1e-68	246
rs:WP_018766530	DNA topoisomerase III [Bacillus sp. 105MF].	31.91	564	336	18	5	548	4	539	1e-68	248
rs:WP_046098044	DNA topoisomerase III [Avibacterium paragallinarum].	29.35	620	376	22	7	593	4	594	1e-68	246
rs:WP_031804216	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	33.33	480	286	11	97	552	2	471	2e-68	244
rs:WP_014602293	DNA topoisomerase III [Listeria monocytogenes].	30.55	622	372	19	5	606	4	585	2e-68	247
rs:WP_004586877	DNA topoisomerase III [Pseudoalteromonas agarivorans].	31.83	556	353	13	8	549	5	548	2e-68	246
rs:WP_044734317	DNA topoisomerase III [Shewanella algae].	30.36	560	359	14	8	548	5	552	2e-68	246
rs:WP_014576643	DNA topoisomerase III [Marinobacter adhaerens].	29.52	542	355	11	8	530	5	538	2e-68	247
rs:WP_045494938	DNA topoisomerase III [Vibrio sp. 151112A].	32.05	596	353	19	7	574	4	575	2e-68	247
rs:WP_028781076	DNA topoisomerase III [Shewanella sp. 38A_GOM-205m].	30.36	560	359	14	8	548	5	552	2e-68	246
rs:WP_003205730	MULTISPECIES: DNA topoisomerase III [Bacillus].	31.91	564	336	18	5	548	4	539	2e-68	247
rs:WP_013660507	DNA topoisomerase III [Marinomonas mediterranea].	29.93	608	389	15	8	593	5	597	2e-68	246
rs:WP_005341866	DNA topoisomerase III [Aeromonas veronii].	29.94	618	390	17	7	602	4	600	2e-68	246
rs:WP_014930286	DNA topoisomerase III [Listeria monocytogenes].	30.55	622	372	19	5	606	4	585	2e-68	247
rs:WP_014601215	DNA topoisomerase III [Listeria monocytogenes].	30.55	622	372	19	5	606	4	585	2e-68	247
rs:WP_021118952	DNA topoisomerase III [Haemophilus parasuis].	28.46	615	389	16	8	602	5	588	2e-68	245
rs:WP_013464239	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	31.60	538	344	11	8	531	5	532	2e-68	245
rs:WP_037372006	DNA topoisomerase, partial [Selenomonas sp. AE3005].	30.37	540	347	12	8	531	5	531	2e-68	246
rs:WP_044470732	DNA topoisomerase III [Mannheimia sp. MG13].	29.74	575	366	16	8	559	5	564	2e-68	245
gpu:CP007685_2786	DNA topoisomerase III [Listeria monocytogenes]	30.55	622	372	19	5	606	4	585	2e-68	247
rs:WP_035519301	DNA topoisomerase III [Haemophilus parasuis].	28.29	615	390	16	8	602	5	588	2e-68	245
rs:WP_013724181	DNA topoisomerase III [Aeromonas veronii].	30.10	618	389	18	7	602	4	600	2e-68	245
rs:WP_001974718	DNA topoisomerase III [Bacillus cereus].	31.53	574	329	19	3	548	2	539	3e-68	247
rs:WP_021116949	DNA topoisomerase III [Haemophilus parasuis].	28.29	615	390	16	8	602	5	588	3e-68	245
rs:WP_025150533	DNA topoisomerase III [Bacillus sp. H1a].	31.98	566	333	18	5	548	4	539	3e-68	247
rs:WP_002174671	DNA topoisomerase III [Bacillus cereus].	31.98	566	333	18	5	548	4	539	3e-68	247
rs:WP_044008984	DNA topoisomerase III [Haemophilus parasuis].	28.29	615	390	16	8	602	5	588	3e-68	245
rs:WP_021112325	DNA topoisomerase III [Haemophilus parasuis].	28.29	615	390	16	8	602	5	588	3e-68	244
rs:WP_035496709	DNA topoisomerase III [Haemophilus parasuis].	28.46	615	389	16	8	602	5	588	3e-68	244
rs:WP_024032345	DNA topoisomerase III [Pseudoalteromonas sp. NW 4327].	31.83	556	353	13	8	549	5	548	4e-68	245
rs:WP_000047282	DNA topoisomerase III [Bacillus cereus].	31.87	568	335	19	3	548	2	539	4e-68	246
gp:CP005384_686	DNA topoisomerase III [Haemophilus parasuis ZJ0906]	28.29	615	390	16	8	602	5	588	4e-68	244
rs:WP_027959218	MULTISPECIES: DNA topoisomerase III [Halomonas].	30.07	562	359	15	8	548	5	553	4e-68	244
rs:WP_042803655	DNA topoisomerase III [Mannheimia haemolytica].	28.73	616	399	17	7	601	4	600	4e-68	244
tr:C7LTI8_DESBD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.23	612	388	15	5	602	4	590	4e-68	244
rs:WP_027895674	DNA topoisomerase [Megasphaera elsdenii].	29.80	604	383	16	7	586	4	590	4e-68	246
rs:WP_000047302	DNA topoisomerase III [Bacillus cereus].	31.87	568	335	19	3	548	2	539	4e-68	246
rs:WP_005615023	DNA topoisomerase III [Actinobacillus pleuropneumoniae].	29.44	574	376	15	4	559	1	563	4e-68	244
rs:WP_009372245	DNA topoisomerase III [Veillonella sp. oral taxon 780].	31.03	551	347	13	7	536	4	542	4e-68	247
rs:WP_024601516	DNA topoisomerase III [Pseudoalteromonas atlantica].	31.97	538	342	12	8	531	5	532	4e-68	244
rs:WP_005897679	DNA topoisomerase III [Aeromonas molluscorum].	28.92	619	396	18	7	603	4	600	5e-68	245
rs:WP_036549645	DNA topoisomerase III [Nitrincola lacisaponensis].	29.65	570	369	15	4	553	2	559	5e-68	244
rs:WP_035525287	DNA topoisomerase III [Haemophilus parasuis].	28.46	615	389	16	8	602	5	588	5e-68	244
rs:WP_021118176	DNA topoisomerase III [Haemophilus parasuis].	28.41	616	390	16	7	602	4	588	5e-68	244
rs:WP_021110768	DNA topoisomerase III [Haemophilus parasuis].	28.29	615	390	16	8	602	5	588	5e-68	244
rs:WP_023267714	DNA topoisomerase III [Shewanella decolorationis].	29.55	626	382	18	8	593	5	611	5e-68	246
rs:WP_035437661	DNA topoisomerase III [Bacillus sp. UNC322MFChir4.1].	32.16	566	332	18	5	548	4	539	5e-68	246
rs:WP_042017937	DNA topoisomerase III [Aeromonas sobria].	29.19	620	392	18	7	602	4	600	5e-68	244
rs:WP_039198970	DNA topoisomerase III [Actinobacillus equuli].	28.73	616	394	16	4	602	1	588	5e-68	244
rs:WP_014108299	DNA topoisomerase III [Glaciecola nitratireducens].	29.15	597	388	15	8	582	5	588	6e-68	244
rs:WP_001140203	DNA topoisomerase III [Bacillus cereus].	31.82	572	326	19	5	548	4	539	6e-68	246
rs:WP_026313232	DNA topoisomerase III [Actinobacillus capsulatus].	28.71	620	389	17	4	602	1	588	6e-68	244
rs:WP_001140210	DNA topoisomerase 3 [Bacillus thuringiensis].	31.82	572	326	19	5	548	4	539	6e-68	246
rs:WP_042054821	DNA topoisomerase III [Aeromonas veronii].	29.68	620	389	19	7	602	4	600	6e-68	244
rs:WP_011622216	DNA topoisomerase III [Shewanella sp. MR-4].	29.55	626	382	18	8	593	5	611	7e-68	245
rs:WP_022497972	DNA topoisomerase [Megasphaera elsdenii CAG:570].	29.80	604	383	16	7	586	4	590	7e-68	245
rs:WP_020405854	DNA topoisomerase [Hahella ganghwensis].	30.55	550	340	13	7	530	4	537	7e-68	245
rs:WP_000047283	DNA topoisomerase III [Bacillus cereus].	31.88	574	327	19	3	548	2	539	7e-68	246
rs:WP_040070032	DNA topoisomerase III [Aeromonas veronii].	29.35	620	391	19	7	602	4	600	7e-68	244
rs:WP_045131647	DNA topoisomerase III [Listeria monocytogenes].	30.13	624	372	19	5	606	4	585	7e-68	245
rs:WP_014016907	DNA topoisomerase [Megasphaera elsdenii].	29.80	604	383	16	7	586	4	590	8e-68	245
rs:WP_035493689	DNA topoisomerase III [Haemophilus parasuis].	28.29	615	390	16	8	602	5	588	8e-68	244
rs:WP_035293839	DNA topoisomerase III [Actinobacillus minor].	28.71	613	390	16	8	602	5	588	8e-68	243
rs:WP_008864255	DNA topoisomerase III [Parasutterella excrementihominis].	31.16	613	375	17	7	590	4	598	8e-68	243
rs:WP_033674455	DNA topoisomerase III [Bacillus gaemokensis].	31.63	569	331	18	5	548	4	539	9e-68	245
rs:WP_039143633	DNA topoisomerase III [Gallibacterium anatis].	30.00	570	356	16	7	548	4	558	9e-68	244
tr:C5S0M3_9PAST	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.66	614	391	16	7	602	18	602	9e-68	244
rs:WP_000047312	DNA topoisomerase III [Bacillus cereus].	31.71	574	328	19	3	548	2	539	9e-68	245
rs:WP_032848987	DNA topoisomerase III, partial [Mannheimia haemolytica].	32.89	456	281	11	8	452	5	446	1e-67	239
rs:WP_019446465	DNA topoisomerase III [Aeromonas sp. 159].	29.52	620	390	19	7	602	4	600	1e-67	244
rs:WP_043812033	DNA topoisomerase III, partial [Desulfomicrobium baculatum].	31.18	558	354	13	5	553	4	540	1e-67	242
rs:WP_001990567	DNA topoisomerase 3 [Bacillus cereus].	31.82	572	326	19	5	548	4	539	1e-67	245
rs:WP_010218667	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	31.66	499	306	12	8	487	5	487	1e-67	240
rs:WP_041588598	DNA topoisomerase III, partial [Thalassolituus oleivorans].	30.24	572	361	15	7	553	4	562	1e-67	243
rs:WP_014991412	DNA topoisomerase III [Actinobacillus suis].	28.73	616	394	16	4	602	1	588	1e-67	243
rs:WP_021615661	DNA topoisomerase [Aggregatibacter sp. oral taxon 458].	30.55	586	356	21	7	559	4	571	1e-67	243
rs:WP_000047317	DNA topoisomerase III [Bacillus thuringiensis].	31.53	574	329	19	3	548	2	539	1e-67	245
tr:W0WJX7_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.92	495	299	11	8	480	5	483	1e-67	239
rs:WP_021114992	DNA topoisomerase III [Haemophilus parasuis].	28.25	616	391	16	7	602	4	588	1e-67	243
rs:WP_039155132	DNA topoisomerase III [Gallibacterium anatis].	28.50	628	398	19	7	603	4	611	1e-67	243
rs:WP_043823102	DNA topoisomerase III [Aeromonas veronii].	29.94	618	390	18	7	602	4	600	1e-67	244
rs:WP_036204086	DNA topoisomerase [Megasphaera elsdenii].	30.20	606	378	18	7	586	4	590	1e-67	245
rs:WP_033918257	DNA topoisomerase III [Listeria monocytogenes].	30.13	624	372	19	5	606	4	585	1e-67	245
rs:WP_039164205	DNA topoisomerase III [Gallibacterium anatis].	29.82	570	357	16	7	548	4	558	1e-67	243
rs:WP_026750054	DNA topoisomerase III [Listeria monocytogenes].	30.13	624	372	19	5	606	4	585	1e-67	245
rs:WP_023043374	DNA topoisomerase III, partial [Photorhabdus temperata].	33.21	524	309	13	40	537	9	517	1e-67	244
rs:WP_021109548	DNA topoisomerase III [Haemophilus parasuis].	28.46	615	389	16	8	602	5	588	1e-67	243
rs:WP_042513694	DNA topoisomerase III [Bacillus anthracis].	31.64	572	327	19	5	548	4	539	1e-67	245
rs:WP_046199027	DNA topoisomerase III [Bacillus sp. UMTAT18].	31.71	574	328	19	3	548	2	539	1e-67	245
rs:WP_011072959	DNA topoisomerase III [Shewanella oneidensis].	29.53	623	383	18	8	590	5	611	1e-67	244
rs:WP_039490448	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	31.72	558	351	15	8	549	5	548	1e-67	243
rs:WP_041416793	DNA topoisomerase III [Shewanella sp. MR-7].	29.55	626	382	18	8	593	5	611	1e-67	244
rs:WP_043526606	DNA topoisomerase III [Halomonas xinjiangensis].	27.89	588	400	13	7	585	4	576	1e-67	243
rs:WP_033114850	DNA topoisomerase III [Aeromonas sp. AE122].	29.94	618	390	18	7	602	4	600	1e-67	243
rs:WP_023548258	DNA topoisomerase III [Listeria monocytogenes].	30.13	624	372	19	5	606	4	585	2e-67	244
rs:WP_004248229	DNA topoisomerase III [Proteus mirabilis].	29.75	558	363	14	7	548	4	548	2e-67	243
rs:WP_035528736	hypothetical protein, partial [Haliea salexigens].	30.48	561	344	16	4	531	1	548	2e-67	243
rs:WP_027709546	DNA topoisomerase III [Zooshikella ganghwensis].	29.79	584	356	14	8	549	5	576	2e-67	243
rs:WP_005712905	DNA topoisomerase III [Haemophilus parasuis].	28.29	615	390	16	8	602	5	588	2e-67	243
rs:WP_004250914	DNA topoisomerase III [Proteus mirabilis].	29.75	558	363	14	7	548	4	548	2e-67	243
rs:WP_000047304	DNA topoisomerase III [Bacillus cereus].	31.87	568	335	19	3	548	2	539	2e-67	244
rs:WP_042031860	DNA topoisomerase III [Aeromonas jandaei].	29.24	619	391	18	7	601	4	599	2e-67	243
tr:Q0HWK8_SHESR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.55	626	382	18	8	593	30	636	2e-67	244
rs:WP_000047313	DNA topoisomerase III [Bacillus thuringiensis].	31.53	574	329	19	3	548	2	539	2e-67	244
rs:WP_041647890	hypothetical protein, partial [Aromatoleum aromaticum].	30.59	546	349	13	8	544	5	529	2e-67	241
rs:WP_000047311	DNA topoisomerase 3 [Bacillus cereus].	31.71	574	328	19	3	548	2	539	2e-67	244
rs:WP_039175406	DNA topoisomerase III [Listeria monocytogenes].	30.39	622	373	19	5	606	4	585	2e-67	244
rs:WP_024608541	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	29.44	557	348	12	8	537	5	543	2e-67	244
rs:WP_000047284	DNA topoisomerase III [Bacillus cereus].	31.71	574	328	19	3	548	2	539	2e-67	244
rs:WP_044427899	DNA topoisomerase III [Mannheimia haemolytica].	30.16	557	308	15	8	548	5	496	2e-67	243
rs:WP_004243257	DNA topoisomerase III [Proteus mirabilis].	29.75	558	363	14	7	548	4	548	2e-67	243
rs:WP_000047305	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	31.87	568	335	19	3	548	2	539	2e-67	244
rs:WP_036182463	DNA topoisomerase III [Lysinibacillus manganicus].	32.09	564	332	18	7	548	6	540	2e-67	244
rs:WP_044790817	DNA topoisomerase III [Bacillus thuringiensis].	31.53	574	329	19	3	548	2	539	2e-67	244
tr:M5DMV3_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.24	572	361	15	7	553	4	562	2e-67	243
rs:WP_016107448	DNA topoisomerase 3 [Bacillus cereus].	31.87	568	335	19	3	548	2	539	2e-67	244
rs:WP_016132338	DNA topoisomerase 3 [Bacillus cereus].	31.74	564	337	18	5	548	4	539	2e-67	244
rs:WP_000047306	DNA topoisomerase III [Bacillus cereus].	31.87	568	335	19	3	548	2	539	2e-67	244
rs:WP_000047316	DNA topoisomerase III [Bacillus cereus].	31.53	574	329	19	3	548	2	539	2e-67	244
rs:WP_005817765	DNA topoisomerase III [Actinobacillus minor].	28.50	614	392	15	7	602	4	588	2e-67	242
rs:WP_000047307	DNA topoisomerase III [Bacillus cereus].	31.87	568	335	19	3	548	2	539	2e-67	244
rs:WP_000047303	DNA topoisomerase III [Bacillus cereus].	31.87	568	335	19	3	548	2	539	2e-67	244
rs:WP_011199909	DNA topoisomerase III [[Mannheimia] succiniciproducens].	29.90	582	366	18	7	563	4	568	2e-67	243
rs:WP_036520289	DNA topoisomerase III [Nitrincola sp. A-D6].	28.43	619	401	19	8	602	5	605	2e-67	243
tr:E8KHI4_9PAST	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.53	617	396	16	3	602	7	595	2e-67	243
sp:TOP3_BACAH	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	31.64	572	327	19	5	548	4	539	3e-67	244
rs:WP_039881886	DNA topoisomerase III [Marinobacter manganoxydans].	29.34	542	356	11	8	530	5	538	3e-67	244
rs:WP_037587648	DNA topoisomerase III, partial [Stenoxybacter acetivorans].	30.62	529	330	13	41	539	1	522	3e-67	241
rs:WP_026917064	DNA topoisomerase III [Haemophilus parasuis].	28.29	615	390	16	8	602	5	588	3e-67	242
rs:WP_014291218	DNA topoisomerase III [Oceanimonas sp. GK1].	29.21	623	389	19	8	601	5	604	3e-67	242
rs:WP_014610819	DNA topoisomerase III [Shewanella putrefaciens].	29.19	627	385	18	8	593	5	613	3e-67	243
rs:WP_011788910	DNA topoisomerase III [Shewanella sp. W3-18-1].	29.19	627	385	18	8	593	5	613	3e-67	244
rs:WP_012089582	DNA topoisomerase III [Shewanella baltica].	29.09	629	383	18	8	593	5	613	3e-67	243
rs:WP_032108805	DNA topoisomerase III [Haemophilus sp. FF7].	29.35	620	380	20	7	595	4	596	3e-67	242
rs:WP_011716543	DNA topoisomerase III [Shewanella sp. ANA-3].	29.39	626	383	18	8	593	5	611	3e-67	243
rs:WP_000047309	DNA topoisomerase III [Bacillus thuringiensis].	31.87	568	335	19	3	548	2	539	3e-67	244
rs:WP_006248941	DNA topoisomerase III [Mannheimia haemolytica].	28.90	616	398	17	7	601	4	600	3e-67	242
rs:WP_016716345	DNA topoisomerase 3 [Bacillus cereus].	31.53	574	329	19	3	548	2	539	3e-67	244
rs:WP_039106785	DNA topoisomerase III, partial [Frischella perrara].	30.38	576	368	14	8	563	11	573	3e-67	241
rs:WP_000047310	DNA topoisomerase III [Bacillus cereus].	31.87	568	335	19	3	548	2	539	3e-67	244
rs:WP_044275906	hypothetical protein, partial [Burkholderia gladioli].	30.99	555	337	14	7	527	8	550	3e-67	240
rs:WP_008137957	DNA topoisomerase III [Pseudoalteromonas sp. BSi20495].	31.72	558	351	15	8	549	5	548	3e-67	242
rs:WP_003730738	DNA topoisomerase III [Listeria monocytogenes].	29.82	617	373	18	5	603	4	578	4e-67	243
rs:WP_012073435	DNA topoisomerase III [Actinobacillus succinogenes].	29.56	609	389	18	7	593	4	594	4e-67	242
rs:WP_038058568	hypothetical protein, partial [Thermodesulfovibrio islandicus].	32.18	547	330	16	5	531	4	529	4e-67	241
rs:WP_001140206	DNA topoisomerase III [Bacillus cereus].	31.64	572	327	19	5	548	4	539	4e-67	244
rs:WP_017222480	DNA topoisomerase III [Moritella dasanensis].	30.99	555	335	15	8	531	5	542	4e-67	242
rs:WP_031578390	DNA topoisomerase [Ruminobacter sp. RM87].	30.55	550	339	13	7	530	4	536	4e-67	243
rs:WP_001140211	DNA topoisomerase III [Bacillus cereus].	31.64	572	327	19	5	548	4	539	4e-67	243
sp:TOP3_BACC1	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	31.53	574	329	19	3	548	2	539	4e-67	243
rs:WP_029437302	DNA topoisomerase III [Bacillus thuringiensis].	31.52	571	333	18	3	548	2	539	4e-67	243
rs:WP_044024448	DNA topoisomerase III [Actinobacillus ureae].	28.57	616	395	16	4	602	1	588	4e-67	242
gp:AE017262_2719	DNA topoisomerase III [Listeria monocytogenes serotype 4b str. F2365]	29.82	617	373	18	5	603	4	578	5e-67	243
rs:WP_006252007	DNA topoisomerase III [Mannheimia haemolytica].	28.94	615	397	17	8	601	5	600	5e-67	241
rs:WP_024608331	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	31.29	556	356	12	8	549	5	548	5e-67	241
rs:WP_042012256	DNA topoisomerase III [Aeromonas fluvialis].	29.94	618	390	18	7	602	4	600	5e-67	242
rs:WP_005701059	DNA topoisomerase III [Aggregatibacter aphrophilus].	30.50	577	362	19	7	559	4	565	5e-67	241
rs:WP_011919518	DNA topoisomerase III [Shewanella putrefaciens].	29.03	627	386	17	8	593	5	613	5e-67	243
rs:WP_036161006	DNA topoisomerase III [Marinomonas ushuaiensis].	28.97	611	393	14	8	593	5	599	5e-67	242
rs:WP_001983848	DNA topoisomerase III [Bacillus cereus].	31.64	572	327	19	5	548	4	539	6e-67	243
rs:WP_020997000	DNA topoisomerase III, partial [Haemophilus parasuis].	29.41	544	350	14	8	531	5	534	6e-67	239
rs:WP_014929862	DNA topoisomerase III [Listeria monocytogenes].	29.82	617	373	18	5	603	4	578	6e-67	243
rs:WP_000241071	DNA topoisomerase III [Bacillus cereus].	32.16	566	332	18	5	548	4	539	6e-67	243
tr:G6YQR7_9ALTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.34	542	356	11	8	530	57	590	6e-67	244
rs:WP_003725309	DNA topoisomerase III [Listeria monocytogenes].	29.82	617	373	18	5	603	4	578	6e-67	243
sp:TOP3_BACCZ	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	31.64	572	327	19	5	548	4	539	6e-67	243
rs:WP_008466850	DNA topoisomerase III [Pseudoalteromonas sp. BSi20439].	31.41	538	345	11	8	531	5	532	6e-67	241
rs:WP_006661664	DNA topoisomerase III [Providencia alcalifaciens].	30.63	568	358	19	8	553	5	558	6e-67	241
tr:A0A0A7S2M8_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.38	576	368	14	8	563	11	573	6e-67	241
rs:WP_012681475	DNA topoisomerase III [Listeria monocytogenes].	29.82	617	373	18	5	603	4	578	6e-67	243
rs:WP_024603831	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	31.47	556	355	13	8	549	5	548	6e-67	241
rs:WP_014929276	DNA topoisomerase III [Listeria monocytogenes].	29.82	617	373	18	5	603	4	578	6e-67	243
rs:WP_041997876	DNA topoisomerase III [Aeromonas bivalvium].	28.99	621	392	19	7	602	4	600	6e-67	242
rs:WP_038472828	DNA topoisomerase III, partial [Acidithiobacillus caldus].	31.13	514	313	11	43	534	18	512	6e-67	240
rs:WP_010554574	DNA topoisomerase III [Pseudoalteromonas arctica].	31.47	556	355	13	8	549	5	548	6e-67	241
rs:WP_003727630	DNA topoisomerase III [Listeria monocytogenes].	29.82	617	373	18	5	603	4	578	6e-67	243
rs:WP_000047265	DNA topoisomerase III [Bacillus cereus].	31.69	568	336	19	3	548	2	539	6e-67	243
rs:WP_010966830	DNA topoisomerase III [Clostridium acetobutylicum].	32.57	565	332	17	7	552	6	540	7e-67	243
rs:WP_043597926	DNA topoisomerase III [Aeromonas diversa].	29.42	622	390	19	7	603	4	601	7e-67	241
rs:WP_031644012	DNA topoisomerase III [Listeria monocytogenes].	30.13	624	372	19	5	606	4	585	7e-67	243
rs:WP_041209572	DNA topoisomerase III [Aeromonas jandaei].	29.08	619	392	18	7	601	4	599	7e-67	242
rs:WP_015062157	DNA topoisomerase III [Salmonella sp. 14].	32.33	498	309	12	1	482	1	486	7e-67	238
rs:WP_000047308	DNA topoisomerase III [Bacillus cereus].	32.07	552	325	18	3	532	2	525	7e-67	243
rs:WP_042467760	DNA topoisomerase III [Aeromonas salmonicida].	29.50	617	394	16	7	602	4	600	7e-67	241
rs:WP_005339851	DNA topoisomerase III [Aeromonas veronii].	29.94	618	390	18	7	602	4	600	7e-67	241
rs:WP_005356359	DNA topoisomerase III [Aeromonas veronii].	29.82	617	390	18	7	601	4	599	7e-67	241
rs:WP_003739949	DNA topoisomerase III [Listeria monocytogenes].	30.13	624	372	19	5	606	4	585	8e-67	243
rs:WP_003728632	DNA topoisomerase III [Listeria monocytogenes].	30.13	624	372	19	5	606	4	585	8e-67	243
rs:WP_040146911	DNA topoisomerase III, partial [Xanthomonas citri].	32.89	456	281	10	4	450	1	440	8e-67	237
rs:WP_034582848	DNA topoisomerase III [Clostridium acetobutylicum].	32.57	565	332	17	7	552	6	540	8e-67	242
rs:WP_009917426	DNA topoisomerase III [Listeria monocytogenes].	29.82	617	373	18	5	603	4	578	8e-67	243
tr:N9TX52_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.42	622	390	19	7	603	4	601	8e-67	241
rs:WP_045108681	DNA topoisomerase III [Moritella viscosa].	30.84	548	345	14	8	531	5	542	8e-67	241
tr:Q5NX65_AROAE	SubName: Full=TopA protein {ECO:0000313|EMBL:CAI10349.1};	30.59	546	349	13	8	544	5	529	8e-67	241
rs:WP_043850762	DNA topoisomerase III [Aeromonas sp. L_1B5_3].	29.08	619	392	18	7	601	4	599	9e-67	241
rs:WP_007587111	DNA topoisomerase III [Pseudoalteromonas sp. BSi20429].	31.29	556	356	13	8	549	5	548	9e-67	241
rs:WP_037587002	DNA topoisomerase III, partial [Stenoxybacter acetivorans].	30.39	510	331	11	41	532	1	504	9e-67	239
rs:WP_007084499	DNA topoisomerase III [Bacillus bataviensis].	31.63	566	335	17	5	548	4	539	9e-67	243
rs:WP_045394961	DNA topoisomerase III [Vibrio rotiferianus].	32.70	575	342	19	8	559	5	557	1e-66	241
rs:WP_000047323	DNA topoisomerase III [Bacillus cereus].	31.36	574	330	19	3	548	2	539	1e-66	243
rs:WP_046790153	DNA topoisomerase III [Salinicoccus halodurans].	32.85	554	312	21	5	532	4	523	1e-66	243
rs:WP_034382965	DNA topoisomerase, partial [Comamonas testosteroni].	29.88	569	357	14	7	548	4	557	1e-66	242
rs:WP_033695435	DNA topoisomerase III [Bacillus weihenstephanensis].	31.60	576	326	19	3	548	2	539	1e-66	243
rs:WP_001140207	DNA topoisomerase III [Bacillus anthracis].	31.47	572	328	19	5	548	4	539	1e-66	243
rs:WP_005318526	DNA topoisomerase III [Aeromonas salmonicida].	29.50	617	394	16	7	602	4	600	1e-66	241
tr:L3QI54_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	32.14	473	294	10	8	468	5	462	1e-66	236
rs:WP_000047294	DNA topoisomerase 3 [Bacillus cereus].	31.60	576	326	19	3	548	2	539	1e-66	242
rs:WP_029686830	DNA topoisomerase III [Tatumella saanichensis].	29.43	564	359	16	7	549	4	549	1e-66	241
rs:WP_023581968	DNA topoisomerase III [Proteus hauseri].	30.05	559	358	15	8	548	5	548	1e-66	241
rs:WP_001140212	DNA topoisomerase III [Bacillus cereus].	31.64	572	327	19	5	548	4	539	1e-66	242
gpu:AP014864_5696	DNA topoisomerase III [Bacillus thuringiensis serovar tolworthi]	31.60	576	326	19	3	548	2	539	1e-66	242
rs:WP_046953758	DNA topoisomerase III [Bacillus cereus].	31.34	568	338	18	3	548	2	539	1e-66	242
rs:WP_000047291	MULTISPECIES: DNA topoisomerase 3 [Bacillus cereus group].	31.60	576	326	19	3	548	2	539	1e-66	242
rs:WP_045861762	hypothetical protein [Alteromonadaceae bacterium Bs12].	28.88	547	359	9	8	532	5	543	1e-66	242
rs:WP_046958857	DNA topoisomerase III [Bacillus cereus].	31.51	568	337	19	3	548	2	539	1e-66	242
rs:WP_000047289	DNA topoisomerase III [Bacillus cereus].	31.51	568	337	19	3	548	2	539	1e-66	242
rs:WP_000047288	DNA topoisomerase III [Bacillus cereus].	31.51	568	337	19	3	548	2	539	1e-66	242
rs:WP_006916694	DNA topoisomerase III [Bacillus sp. GeD10].	31.60	576	326	19	3	548	2	539	1e-66	242
sp:TOP3_BACCR	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	31.60	576	326	19	3	548	2	539	1e-66	242
rs:WP_005753511	DNA topoisomerase III [Pasteurella multocida].	29.69	586	364	18	8	559	5	576	1e-66	241
rs:WP_016125362	DNA topoisomerase 3 [Bacillus cereus].	31.60	576	326	19	3	548	2	539	1e-66	242
rs:WP_008253114	DNA topoisomerase III [Limnobacter sp. MED105].	33.39	560	331	17	7	546	4	541	1e-66	241
rs:WP_019554952	DNA topoisomerase III [Propionispira raffinosivorans].	34.10	566	331	20	1	550	1	540	1e-66	242
rs:WP_002151617	DNA topoisomerase III [Bacillus cereus].	31.27	566	337	19	5	548	4	539	1e-66	242
rs:WP_025710032	DNA topoisomerase III [Bacillus subtilis].	31.60	576	326	19	3	548	2	539	1e-66	242
rs:WP_019677543	DNA topoisomerase III [Rheinheimera perlucida].	29.68	620	382	21	8	593	5	604	1e-66	241
tr:A0A0E3BE52_COMTE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KGG84401.1};	29.88	569	357	14	7	548	2	555	1e-66	242
rs:WP_044337321	DNA topoisomerase III [Bacillus aquimaris].	31.24	621	366	26	7	603	6	589	1e-66	242
rs:WP_020585005	DNA topoisomerase III [Endozoicomonas elysicola].	30.81	555	337	14	7	531	4	541	2e-66	240
rs:WP_021139862	DNA topoisomerase III [Aeromonas salmonicida].	29.50	617	394	16	7	602	4	600	2e-66	241
rs:WP_046179383	DNA topoisomerase III [Domibacillus sp. PAMC 80007].	31.87	571	323	19	7	548	6	539	2e-66	242
rs:WP_004698401	DNA topoisomerase [Veillonella parvula].	29.94	618	386	19	8	598	5	602	2e-66	241
rs:WP_027966602	DNA topoisomerase III [Halomonas halocynthiae].	31.17	571	353	19	7	553	4	558	2e-66	240
rs:WP_041637066	DNA topoisomerase III, partial [Acidithiobacillus caldus].	30.63	542	323	12	15	534	2	512	2e-66	239
rs:WP_021279340	DNA topoisomerase III [Mannheimia haemolytica].	28.73	616	399	17	7	601	4	600	2e-66	240
rs:WP_000047296	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	31.60	576	326	19	3	548	2	539	2e-66	242
rs:WP_047225405	DNA topoisomerase III [Bacillus thuringiensis].	31.42	576	327	19	3	548	2	539	2e-66	241
rs:WP_000047292	DNA topoisomerase III [Bacillus cereus].	31.60	576	326	19	3	548	2	539	2e-66	242
rs:WP_043004022	DNA topoisomerase III, partial [Vibrio anguillarum].	30.07	562	361	14	8	549	5	554	2e-66	239
rs:WP_042082863	DNA topoisomerase III [Aeromonas veronii].	29.53	613	393	17	7	597	4	599	2e-66	240
rs:WP_004035914	DNA topoisomerase III [Clostridium sp. ASF356].	30.03	576	353	19	1	559	1	543	2e-66	241
rs:WP_011983474	DNA topoisomerase III [Bacillus cytotoxicus].	31.29	572	329	19	5	548	4	539	2e-66	241
rs:WP_016089486	DNA topoisomerase 3 [Bacillus cereus].	31.51	568	337	19	3	548	2	539	2e-66	241
rs:WP_012587335	DNA topoisomerase III [Shewanella baltica].	29.09	629	383	18	8	593	5	613	3e-66	241
rs:WP_016133523	DNA topoisomerase 3 [Bacillus cereus].	31.51	568	337	19	3	548	2	539	3e-66	241
rs:WP_024589767	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	31.47	556	355	13	8	549	5	548	3e-66	239
rs:WP_012582298	DNA topoisomerase III [Listeria monocytogenes].	30.72	625	367	22	5	606	4	585	3e-66	241
rs:WP_005357612	DNA topoisomerase III [Aeromonas veronii].	29.29	618	394	18	7	602	4	600	3e-66	240
rs:WP_025117795	DNA topoisomerase III [Bacillus sp. H1m].	31.18	574	331	18	3	548	2	539	3e-66	241
rs:WP_003740322	DNA topoisomerase III [Listeria monocytogenes].	29.66	617	374	18	5	603	4	578	3e-66	241
rs:WP_006693725	DNA topoisomerase TopB [Selenomonas noxia].	30.05	559	332	17	8	531	5	539	3e-66	241
rs:WP_007377458	MULTISPECIES: DNA topoisomerase III [Pseudoalteromonas].	31.54	558	352	15	8	549	5	548	3e-66	239
tr:C2Z2K2_BACCE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.10	566	338	19	5	548	8	543	3e-66	241
rs:WP_000047300	MULTISPECIES: DNA topoisomerase III [Bacillus].	31.42	576	327	19	3	548	2	539	3e-66	241
rs:WP_000047299	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	31.42	576	327	19	3	548	2	539	3e-66	241
rs:WP_036127568	MULTISPECIES: DNA topoisomerase III [Lysinibacillus].	30.97	607	365	20	7	590	6	581	3e-66	241
rs:WP_030022716	DNA topoisomerase III [Bacillus thuringiensis].	31.42	576	327	19	3	548	2	539	3e-66	241
rs:WP_036936365	DNA topoisomerase III [Proteus vulgaris].	30.25	562	355	16	7	548	4	548	3e-66	239
rs:WP_002113637	DNA topoisomerase III [Bacillus cereus].	31.10	566	338	19	5	548	4	539	3e-66	241
rs:WP_016112910	DNA topoisomerase 3 [Bacillus cereus].	31.56	564	338	18	5	548	4	539	3e-66	241
rs:WP_036145479	DNA topoisomerase III [Lysinibacillus fusiformis].	30.97	607	365	20	7	590	6	581	3e-66	241
tr:L8U5T5_AGGAC	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.21	623	381	22	7	595	4	600	3e-66	239
rs:WP_000047298	DNA topoisomerase III [Bacillus cereus].	31.42	576	327	19	3	548	2	539	3e-66	241
rs:WP_006085455	DNA topoisomerase III [Shewanella baltica].	29.09	629	383	18	8	593	5	613	3e-66	241
rs:WP_011961680	DNA topoisomerase III [Haemophilus influenzae].	28.10	580	376	15	8	559	5	571	3e-66	239
rs:WP_036218131	DNA topoisomerase III, partial [Lysinibacillus sphaericus].	30.97	607	365	20	7	590	6	581	3e-66	240
rs:WP_000047290	DNA topoisomerase III [Bacillus cereus].	31.42	576	327	19	3	548	2	539	3e-66	241
rs:WP_001129909	DNA topoisomerase III [Bacillus cereus].	31.10	566	338	19	5	548	4	539	3e-66	241
rs:WP_044307355	DNA topoisomerase III [Bacillus cereus].	31.42	576	327	19	3	548	2	539	4e-66	241
rs:WP_000047287	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	31.42	576	327	19	3	548	2	539	4e-66	241
rs:WP_016117101	DNA topoisomerase 3 [Bacillus cereus].	31.36	574	326	19	5	548	4	539	4e-66	241
rs:WP_001140205	DNA topoisomerase III [Bacillus cereus].	31.36	574	326	19	5	548	4	539	4e-66	241
rs:WP_006082217	DNA topoisomerase III [Shewanella baltica].	29.38	633	376	19	8	593	5	613	4e-66	241
rs:WP_016079170	DNA topoisomerase 3 [Bacillus cereus].	31.10	566	338	19	5	548	4	539	4e-66	241
rs:WP_002159436	DNA topoisomerase III [Bacillus cereus].	31.10	566	338	19	5	548	4	539	4e-66	241
rs:WP_010857857	DNA topoisomerase III [Lysinibacillus sphaericus].	31.38	564	339	18	5	548	4	539	4e-66	241
rs:WP_017762755	DNA topoisomerase III [Bacillus thuringiensis].	31.36	574	330	19	3	548	2	539	4e-66	241
rs:WP_001129910	DNA topoisomerase III [Bacillus cereus].	30.94	572	331	19	5	548	4	539	4e-66	241
rs:WP_014326230	DNA topoisomerase III [Pasteurella multocida].	30.61	588	356	20	8	559	5	576	4e-66	239
rs:WP_036166771	DNA topoisomerase III, partial [Lysinibacillus sphaericus].	30.97	607	365	20	7	590	6	581	4e-66	240
tr:G7EED8_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.94	556	358	13	8	549	12	555	4e-66	239
rs:WP_000047286	DNA topoisomerase III [Bacillus cereus].	31.42	576	327	19	3	548	2	539	4e-66	241
rs:WP_023520977	DNA topoisomerase III [Bacillus thuringiensis].	31.42	576	327	19	3	548	2	539	4e-66	241
rs:WP_025264565	DNA topoisomerase III [Thalassolituus oleivorans].	29.55	572	365	14	7	553	4	562	4e-66	239
rs:WP_001129908	DNA topoisomerase III [Bacillus cereus].	31.10	566	338	19	5	548	4	539	4e-66	241
tr:C2YLG1_BACCE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.94	572	331	19	5	548	8	543	4e-66	241
rs:WP_035416335	DNA topoisomerase III [Ferrimonas kyonanensis].	29.60	625	388	20	8	603	5	606	4e-66	239
tr:C6I107_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.84	563	338	13	7	548	4	530	4e-66	241
rs:WP_000047320	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	31.36	574	330	19	3	548	2	539	4e-66	241
rs:WP_024612236	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	31.29	556	356	13	8	549	5	548	4e-66	239
rs:WP_013052140	DNA topoisomerase III [Shewanella violacea].	30.07	552	348	12	8	531	5	546	4e-66	239
sp:TOP3_HAEIN	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	29.64	587	366	19	8	563	5	575	4e-66	239
rs:WP_042650606	DNA topoisomerase III [Aeromonas media].	29.77	561	360	14	7	549	4	548	4e-66	239
rs:WP_025289344	DNA topoisomerase III [Bibersteinia trehalosi].	28.46	615	389	17	8	602	5	588	4e-66	239
rs:WP_017411783	DNA topoisomerase III [Aeromonas salmonicida].	29.50	617	394	16	7	602	4	600	5e-66	239
rs:WP_005332660	DNA topoisomerase III [Aeromonas media].	29.77	561	360	14	7	549	4	548	5e-66	239
rs:WP_016128273	DNA topoisomerase 3 [Bacillus cereus].	31.10	566	338	19	5	548	4	539	5e-66	241
rs:WP_015432516	DNA topoisomerase III [Bibersteinia trehalosi].	28.46	615	389	17	8	602	5	588	5e-66	239
rs:WP_000047278	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	31.42	576	327	19	3	548	2	539	5e-66	241
rs:WP_033017260	DNA topoisomerase III [Pseudoalteromonas sp. BSi20652].	30.94	556	358	13	8	549	5	548	5e-66	239
tr:I7B516_PSEPT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.07	449	288	9	7	450	4	440	5e-66	234
rs:WP_000047297	DNA topoisomerase III [Bacillus cereus].	31.42	576	327	19	3	548	2	539	5e-66	240
rs:WP_014093960	DNA topoisomerase III [Listeria ivanovii].	29.98	617	372	18	5	603	4	578	5e-66	240
rs:WP_003772809	DNA topoisomerase III [Listeria innocua].	30.13	624	372	20	5	606	4	585	5e-66	240
rs:WP_000047318	DNA topoisomerase III [Bacillus cereus].	31.36	574	330	19	3	548	2	539	6e-66	240
rs:WP_000241072	DNA topoisomerase III [Bacillus cereus].	31.45	566	336	19	5	548	4	539	6e-66	240
rs:WP_046392322	DNA topoisomerase III [Bacillus cereus].	31.25	576	328	19	3	548	2	539	6e-66	240
rs:WP_006995139	MULTISPECIES: DNA topoisomerase III [Haemophilus].	28.82	583	370	16	7	559	4	571	6e-66	239
rs:WP_033032254	DNA topoisomerase III [Pseudoalteromonas citrea].	31.54	558	352	15	8	549	5	548	6e-66	239
tr:C2SEV4_BACCE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.92	566	339	19	5	548	8	543	6e-66	240
rs:WP_040552170	DNA topoisomerase III, partial [Rheinheimera nanhaiensis].	27.70	639	400	18	8	603	5	624	6e-66	238
rs:WP_040198136	DNA topoisomerase III [Candidatus Soleaferrea massiliensis].	30.60	562	347	17	1	550	1	531	6e-66	240
rs:WP_001129907	DNA topoisomerase III [Bacillus cereus].	31.10	566	338	19	5	548	4	539	6e-66	240
rs:WP_020061674	DNA topoisomerase III [Bacillus sp. 123MFChir2].	30.70	570	335	16	5	548	4	539	6e-66	240
rs:WP_000047321	DNA topoisomerase III [Bacillus cereus].	31.45	566	340	18	3	548	2	539	7e-66	240
rs:WP_002091243	DNA topoisomerase III [Bacillus cereus].	30.92	566	339	19	5	548	4	539	7e-66	240
rs:WP_002130832	DNA topoisomerase III [Bacillus cereus].	30.76	569	336	19	5	548	4	539	7e-66	240
rs:WP_009601820	DNA topoisomerase III [Vibrio caribbeanicus].	30.80	565	353	15	7	548	5	554	7e-66	239
rs:WP_002124971	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.92	566	339	19	5	548	4	539	7e-66	240
rs:WP_043132818	DNA topoisomerase III [Aeromonas media].	29.77	561	360	14	7	549	4	548	7e-66	239
rs:WP_002961727	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	31.36	558	353	15	8	549	5	548	7e-66	238
rs:WP_000047280	DNA topoisomerase III [Bacillus thuringiensis].	31.42	576	327	19	3	548	2	539	7e-66	240
rs:WP_024026550	DNA topoisomerase III [Bacillus vireti].	31.45	566	336	18	5	548	4	539	7e-66	240
rs:WP_019615207	DNA topoisomerase III [Psychromonas ossibalaenae].	29.51	610	399	14	8	601	5	599	7e-66	238
rs:WP_008929975	DNA topoisomerase [Alcanivorax hongdengensis].	30.67	551	339	12	7	530	4	538	7e-66	239
rs:WP_037420090	DNA topoisomerase III [Shewanella xiamenensis].	29.00	631	384	18	8	593	5	616	8e-66	239
rs:WP_016097640	DNA topoisomerase 3 [Bacillus cereus].	31.42	576	327	19	3	548	2	539	8e-66	240
tr:C2XNU9_BACCE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.92	566	339	19	5	548	8	543	8e-66	240
rs:WP_002140241	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.74	566	340	19	5	548	4	539	8e-66	240
rs:WP_000047279	DNA topoisomerase III [Bacillus cereus].	31.25	576	328	19	3	548	2	539	8e-66	240
rs:WP_041918412	DNA topoisomerase III [Listeria innocua].	30.13	624	372	20	5	606	4	585	8e-66	240
tr:C2Q4N3_BACCE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.74	566	340	19	5	548	8	543	8e-66	240
rs:WP_011847173	DNA topoisomerase III [Shewanella baltica].	29.09	629	383	18	8	593	5	613	8e-66	239
rs:WP_033706351	DNA topoisomerase III [Bacillus cereus].	30.92	566	339	19	5	548	4	539	9e-66	240
rs:WP_029441506	DNA topoisomerase III [Bacillus thuringiensis].	31.42	576	327	19	3	548	2	539	9e-66	240
rs:WP_031418403	DNA topoisomerase III [Lysinibacillus sphaericus].	30.97	607	365	20	7	590	6	581	9e-66	240
rs:WP_016097005	DNA topoisomerase 3 [Bacillus cereus].	30.92	566	339	19	5	548	4	539	9e-66	240
rs:WP_000047301	DNA topoisomerase III [Bacillus cereus].	31.66	578	323	20	3	548	2	539	9e-66	240
rs:WP_012142005	DNA topoisomerase III [Shewanella sediminis].	29.37	572	361	13	8	548	5	564	9e-66	239
rs:WP_036162559	DNA topoisomerase III [Lysinibacillus sphaericus].	30.97	607	365	20	7	590	6	581	9e-66	240
rs:WP_043937735	MULTISPECIES: DNA topoisomerase III [Bacillus].	31.42	576	327	19	3	548	2	539	1e-65	240
rs:WP_000047319	DNA topoisomerase III [Bacillus thuringiensis].	31.36	574	330	19	3	548	2	539	1e-65	239
rs:WP_027252817	DNA topoisomerase III [Photobacterium halotolerans].	29.54	562	367	12	8	552	6	555	1e-65	238
rs:WP_005691383	DNA topoisomerase III [Haemophilus influenzae].	29.57	585	361	19	8	559	5	571	1e-65	238
rs:WP_044784126	DNA topoisomerase III [Bacillus thuringiensis].	31.80	566	334	19	5	548	4	539	1e-65	239
rs:WP_017456522	DNA topoisomerase III [Kosakonia sacchari].	30.24	582	362	18	7	563	4	566	1e-65	238
rs:WP_042048532	DNA topoisomerase III [Aeromonas simiae].	28.82	621	395	18	7	603	4	601	1e-65	238
rs:WP_040976203	DNA topoisomerase III [Pasteurella sp. FF6].	28.99	614	388	19	8	595	5	596	1e-65	238
tr:B1HZX0_LYSSC	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.97	607	365	20	7	590	9	584	1e-65	239
rs:WP_021535386	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	1e-65	238
rs:WP_045511565	DNA topoisomerase III [Kosakonia oryzae].	30.24	582	362	18	7	563	4	566	1e-65	238
rs:WP_021996258	DNA topoisomerase [Clostridium sp. CAG:780].	31.22	583	326	19	7	532	6	570	1e-65	238
rs:WP_005756024	DNA topoisomerase III [Pasteurella multocida].	30.22	589	359	20	7	559	4	576	1e-65	238
rs:WP_042610999	DNA topoisomerase III [Haemophilus influenzae].	28.87	582	371	17	7	559	4	571	1e-65	238
rs:WP_039847764	DNA topoisomerase III, partial [Haemophilus pittmaniae].	28.04	617	393	16	8	602	5	592	1e-65	237
rs:WP_000047295	DNA topoisomerase III [Bacillus cereus].	31.42	576	327	19	3	548	2	539	1e-65	239
rs:WP_008937881	DNA topoisomerase III [Marinobacter santoriniensis].	28.24	563	371	14	8	549	5	555	1e-65	239
rs:WP_000047281	DNA topoisomerase III [Bacillus cereus].	31.08	576	329	19	3	548	2	539	1e-65	239
rs:WP_042317047	DNA topoisomerase III, partial [Desulfotomaculum acetoxidans].	31.14	578	341	18	7	559	6	551	2e-65	238
rs:WP_013625182	DNA topoisomerase III [Syntrophobotulus glycolicus].	29.37	606	376	19	7	590	6	581	2e-65	239
rs:WP_027859721	DNA topoisomerase III [Marinobacterium jannaschii].	28.89	540	357	15	2	531	4	526	2e-65	239
rs:WP_044795633	DNA topoisomerase III [Bacillus cereus].	31.18	574	327	19	5	548	4	539	2e-65	239
rs:WP_020909946	DNA topoisomerase III [Haemophilus influenzae].	28.35	589	373	17	7	563	4	575	2e-65	238
rs:WP_005430340	DNA topoisomerase [Sutterella wadsworthensis].	30.73	550	338	15	8	530	5	538	2e-65	237
rs:WP_033131258	DNA topoisomerase III [Aeromonas sp. AE235].	29.77	561	360	15	7	549	4	548	2e-65	238
rs:WP_018999978	DNA topoisomerase III [Megamonas rupellensis].	31.55	561	325	13	8	531	5	543	2e-65	240
rs:WP_027847842	DNA topoisomerase III [Marinospirillum minutulum].	29.77	561	362	13	8	548	5	553	2e-65	237
rs:WP_016103425	DNA topoisomerase 3 [Bacillus cereus].	30.92	566	339	19	5	548	4	539	2e-65	239
rs:WP_037319108	hypothetical protein, partial [Ruminobacter sp. RM87].	29.78	591	353	14	8	550	12	588	2e-65	237
rs:WP_008176132	DNA topoisomerase III [Bacillus sp. B14905].	30.85	564	343	17	5	548	4	540	2e-65	239
rs:WP_038191560	DNA topoisomerase III [Vibrio sinaloensis].	30.27	565	355	17	7	548	5	553	2e-65	238
rs:WP_009500211	DNA topoisomerase III [Haemophilus sp. oral taxon 851].	28.57	581	372	16	8	559	5	571	2e-65	237
rs:WP_005626523	DNA topoisomerase III [Haemophilus haemolyticus].	29.79	584	363	19	7	559	4	571	2e-65	237
rs:WP_046333399	DNA topoisomerase III [Pasteurella multocida].	30.27	588	358	20	8	559	5	576	2e-65	237
rs:WP_016708066	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	31.97	538	342	12	8	531	5	532	2e-65	237
rs:WP_027156703	DNA topoisomerase [Methylobacter luteus].	30.00	590	368	15	7	564	4	580	2e-65	238
rs:WP_029655590	DNA topoisomerase III [Marinobacter daepoensis].	30.05	549	343	14	8	530	5	538	2e-65	238
rs:WP_010647795	DNA topoisomerase III [Oceanobacillus massiliensis].	32.14	557	325	20	1	536	1	525	2e-65	238
tr:C8VYF5_DESAS	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.14	578	341	18	7	559	5	550	2e-65	238
rs:WP_033533770	DNA topoisomerase III [Listeria innocua].	29.97	624	373	20	5	606	4	585	3e-65	238
rs:WP_019243290	DNA topoisomerase III [Bacillus massilioanorexius].	31.63	569	331	19	5	548	4	539	3e-65	238
tr:A0A0A6ZS57_SHIDY	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.87	568	375	14	1	552	17	571	3e-65	236
rs:WP_008950433	DNA topoisomerase III [Alishewanella jeotgali].	28.90	571	360	13	8	549	5	558	3e-65	237
rs:WP_029053986	DNA topoisomerase III [Sporosarcina ureae].	30.93	569	336	18	5	548	4	540	3e-65	238
tr:F9Q6Z6_9PAST	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.04	617	393	16	8	602	5	592	3e-65	237
rs:WP_019740450	DNA topoisomerase III, partial [Pseudomonas savastanoi].	32.68	462	282	10	107	549	4	455	3e-65	235
tr:F2F8B2_SOLSS	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.67	562	335	17	7	548	9	541	3e-65	238
rs:WP_021034374	DNA topoisomerase III [Haemophilus influenzae].	28.25	623	388	18	8	602	5	596	3e-65	237
tr:I1E068_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.67	579	363	15	8	548	5	571	3e-65	237
rs:WP_037430092	DNA topoisomerase III [Shewanella sp. POL2].	28.84	631	385	18	8	593	5	616	3e-65	238
sp:TOP3_PASMU	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	30.27	588	358	20	8	559	5	576	3e-65	237
rs:WP_041865800	DNA topoisomerase III [Solibacillus silvestris].	31.67	562	335	17	7	548	6	538	3e-65	238
rs:WP_042072495	DNA topoisomerase III [Aeromonas enteropelogenes].	31.31	543	340	14	7	530	4	532	3e-65	237
rs:WP_039207770	DNA topoisomerase [Anaerovibrio lipolyticus].	31.82	572	323	17	8	536	5	552	4e-65	239
rs:WP_007374606	DNA topoisomerase III [Kosakonia radicincitans].	30.07	582	363	18	7	563	4	566	4e-65	237
rs:WP_014708275	DNA topoisomerase [Methylophaga frappieri].	30.49	551	340	12	7	530	4	538	4e-65	237
rs:WP_008404653	DNA topoisomerase III [Bacillus isronensis].	31.67	562	335	17	7	548	6	538	4e-65	238
rs:WP_031828430	DNA topoisomerase III [Vibrio parahaemolyticus].	31.00	558	349	14	8	548	5	543	4e-65	237
rs:WP_001235788	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	4e-65	237
rs:WP_008537480	DNA topoisomerase III [Megamonas funiformis].	30.00	590	388	17	8	585	5	581	4e-65	238
rs:WP_033867744	DNA topoisomerase III, partial [Escherichia coli].	29.18	562	369	14	7	552	4	552	4e-65	236
rs:WP_005751158	DNA topoisomerase III [Pasteurella multocida].	30.10	588	359	20	8	559	5	576	4e-65	236
rs:WP_034914838	DNA topoisomerase III, partial [Gilliamella apicola].	28.80	618	396	17	3	593	6	606	4e-65	236
rs:WP_040047798	DNA topoisomerase III [Bacillaceae bacterium MTCC 8252].	31.31	559	342	17	3	548	2	531	4e-65	238
rs:WP_024603571	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	31.36	558	353	15	8	549	5	548	4e-65	236
rs:WP_036833466	DNA topoisomerase III [Pontibacillus litoralis].	30.66	561	342	16	7	548	6	538	4e-65	238
rs:WP_044739928	DNA topoisomerase III [Bacillus mycoides].	30.92	566	339	19	5	548	4	539	4e-65	238
rs:WP_035886129	DNA topoisomerase III [Kosakonia radicincitans].	30.07	582	363	18	7	563	4	566	4e-65	236
rs:WP_042356994	DNA topoisomerase III [Bacillus sp. MT2].	30.50	564	344	16	5	548	4	539	4e-65	238
rs:WP_035385321	DNA topoisomerase III, partial [Ferrimonas futtsuensis].	30.00	560	360	15	8	549	5	550	4e-65	236
rs:WP_002139479	DNA topoisomerase III [Bacillus cereus].	30.74	566	340	19	5	548	4	539	5e-65	238
rs:WP_010365922	DNA topoisomerase III [Pseudoalteromonas citrea].	29.01	617	401	17	8	604	5	604	5e-65	236
rs:WP_040034471	DNA topoisomerase III [Haemophilus influenzae].	28.06	581	377	15	7	559	4	571	5e-65	236
rs:WP_001235828	DNA topoisomerase III [Escherichia sp. TW09231].	29.18	562	369	14	7	552	4	552	5e-65	236
rs:WP_025115491	DNA topoisomerase III [Lysinibacillus fusiformis].	30.74	566	341	17	5	548	4	540	5e-65	238
rs:WP_027397710	DNA topoisomerase [Anaerovibrio lipolyticus].	31.83	575	319	19	8	536	5	552	5e-65	239
rs:WP_005641248	DNA topoisomerase III [Haemophilus haemolyticus].	28.74	581	371	16	8	559	5	571	5e-65	236
rs:WP_005639112	DNA topoisomerase III [Haemophilus haemolyticus].	28.87	582	369	17	8	559	5	571	5e-65	236
rs:WP_015701651	DNA topoisomerase III [Haemophilus influenzae].	28.87	582	371	17	7	559	4	571	5e-65	236
rs:WP_027662357	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	5e-65	236
rs:WP_032238281	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	5e-65	236
rs:WP_001140199	DNA topoisomerase III [Bacillus cereus].	31.53	574	325	19	5	548	4	539	5e-65	238
rs:WP_016083678	DNA topoisomerase 3 [Bacillus cereus].	31.25	576	328	19	3	548	2	539	5e-65	238
rs:WP_012602298	DNA topoisomerase III [Escherichia coli].	28.87	568	375	14	1	552	17	571	5e-65	236
rs:WP_017350143	DNA topoisomerase III [Pasteurella multocida].	30.05	589	360	20	7	559	4	576	5e-65	236
rs:WP_023564812	DNA topoisomerase III, partial [Escherichia coli].	29.08	557	366	14	8	548	5	548	5e-65	234
rs:WP_001235827	MULTISPECIES: DNA topoisomerase III [Escherichia].	29.18	562	369	14	7	552	4	552	5e-65	236
rs:WP_001235814	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	5e-65	236
rs:WP_014064795	DNA topoisomerase III [Haemophilus parainfluenzae].	27.77	623	387	18	8	602	5	592	6e-65	236
rs:WP_022953535	DNA topoisomerase III [Leucothrix mucor].	28.57	595	364	15	8	553	5	587	6e-65	236
tr:C9LWM4_SELS3	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.01	556	345	18	5	550	6	538	6e-65	237
rs:WP_024597194	DNA topoisomerase III [Pseudoalteromonas haloplanktis].	31.36	558	353	15	8	549	5	548	6e-65	236
tr:A0A0C2C2I1_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.31	559	342	17	3	548	13	542	6e-65	238
rs:WP_021550670	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	6e-65	236
rs:WP_032281001	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	6e-65	236
tr:F4SKI5_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.87	568	375	14	1	552	7	561	6e-65	236
rs:WP_032353289	DNA topoisomerase III, partial [Escherichia coli].	29.00	562	370	14	7	552	4	552	6e-65	235
rs:WP_040659182	DNA topoisomerase III, partial [Neisseria bacilliformis].	30.53	511	324	11	54	539	1	505	6e-65	234
rs:WP_032218329	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	6e-65	236
rs:WP_006714205	DNA topoisomerase III [Vibrio ichthyoenteri].	31.60	576	335	19	4	547	1	549	6e-65	237
rs:WP_042078806	DNA topoisomerase III [Aeromonas sanarellii].	30.02	563	356	15	7	549	4	548	6e-65	236
tr:D4M8T1_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.11	553	365	9	7	543	4	545	6e-65	236
rs:WP_011703393	DNA topoisomerase III [Listeria welshimeri].	29.65	624	375	19	5	606	4	585	6e-65	237
rs:WP_013740648	DNA topoisomerase III [Selenomonas sputigena].	32.01	556	345	18	5	550	5	537	6e-65	237
rs:WP_001235836	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	6e-65	236
rs:WP_005723459	DNA topoisomerase III [Pasteurella multocida].	30.27	588	358	20	8	559	5	576	6e-65	236
rs:WP_006696787	hypothetical protein [Selenomonas noxia].	29.52	559	335	17	8	531	5	539	7e-65	237
rs:WP_007495750	DNA topoisomerase III [Flavonifractor plautii].	30.35	626	374	22	5	601	4	596	7e-65	237
rs:WP_007938669	MULTISPECIES: DNA topoisomerase III [Pelosinus].	31.43	544	338	12	7	531	4	531	7e-65	236
rs:WP_043762485	DNA topoisomerase III [Aeromonas taiwanensis].	29.50	617	392	18	7	601	4	599	7e-65	236
rs:WP_018395581	DNA topoisomerase III [Bacillus sp. 37MA].	31.06	573	329	18	5	548	4	539	7e-65	237
rs:WP_045177124	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	7e-65	236
tr:F4VG14_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.87	568	375	14	1	552	7	561	7e-65	236
rs:WP_040206221	MULTISPECIES: DNA topoisomerase III [Bacillus].	31.12	572	334	18	3	548	2	539	7e-65	237
rs:WP_038439372	DNA topoisomerase III [Haemophilus influenzae].	28.69	582	372	17	7	559	4	571	7e-65	236
rs:WP_014550410	DNA topoisomerase III [Haemophilus influenzae].	28.69	582	372	17	7	559	4	571	7e-65	236
rs:WP_028293801	DNA topoisomerase III [Oceanobacter kriegii].	29.91	555	345	13	7	531	4	544	7e-65	236
rs:WP_009257548	DNA topoisomerase III [Lachnospiraceae bacterium 7_1_58FAA].	30.19	626	375	21	5	601	4	596	8e-65	237
rs:WP_004225545	DNA topoisomerase III [Lysinibacillus fusiformis].	30.93	569	336	19	5	548	4	540	8e-65	237
rs:WP_024362789	DNA topoisomerase III [Lysinibacillus sphaericus].	31.14	562	340	17	7	548	6	540	8e-65	237
rs:WP_033553586	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	8e-65	236
rs:WP_005686905	DNA topoisomerase III [Haemophilus influenzae].	27.93	580	377	15	8	559	5	571	8e-65	236
rs:WP_006032728	DNA topoisomerase III [Moritella sp. PE36].	30.47	548	347	14	8	531	5	542	8e-65	236
rs:WP_025328625	DNA topoisomerase III [Aeromonas hydrophila].	28.32	618	397	17	7	601	4	598	8e-65	236
tr:F4V2S6_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.87	568	375	14	1	552	7	561	8e-65	236
rs:WP_036078130	DNA topoisomerase III [Lysinibacillus boronitolerans].	31.35	571	331	20	5	548	4	540	8e-65	237
rs:WP_012602800	DNA topoisomerase III [Escherichia coli].	28.87	568	375	14	1	552	17	571	8e-65	236
rs:WP_033814661	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	8e-65	236
rs:WP_036198354	DNA topoisomerase III [Lysinibacillus sinduriensis].	31.51	568	328	20	7	548	6	538	8e-65	237
tr:B7MVP0_ECO81	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.87	568	375	14	1	552	17	571	8e-65	236
rs:WP_009766587	DNA topoisomerase III [Sporosarcina newyorkensis].	30.39	566	344	16	5	548	4	541	8e-65	237
rs:WP_005634570	DNA topoisomerase III [Haemophilus haemolyticus].	28.28	580	375	15	8	559	5	571	9e-65	236
rs:WP_013526469	DNA topoisomerase III [Haemophilus influenzae].	29.16	583	366	18	8	559	5	571	9e-65	236
rs:WP_038408056	DNA topoisomerase III [Listeria ivanovii].	29.66	617	374	18	5	603	4	578	9e-65	237
tr:F4NFA1_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.87	568	375	14	1	552	17	571	9e-65	236
rs:WP_029435132	DNA topoisomerase III [Bilophila wadsworthia].	29.44	557	356	13	7	550	4	536	9e-65	238
rs:WP_001235852	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	9e-65	236
rs:WP_041028003	DNA topoisomerase III, partial [Salmonella enterica].	28.83	562	371	14	7	552	4	552	9e-65	233
rs:WP_021531349	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	9e-65	236
rs:WP_019807124	DNA topoisomerase III [Osedax symbiont Rs1].	30.50	564	353	15	8	549	5	551	9e-65	235
rs:WP_041028603	DNA topoisomerase III, partial [Salmonella enterica].	28.83	562	371	14	7	552	4	552	9e-65	234
tr:F9GN99_HAEHA	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.87	582	369	17	8	559	5	571	9e-65	235
rs:WP_001613225	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	9e-65	236
rs:WP_038409316	DNA topoisomerase III [Listeria ivanovii].	29.66	617	374	18	5	603	4	578	9e-65	237
rs:WP_024704803	DNA topoisomerase III, partial [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-64	234
rs:WP_039517865	DNA topoisomerase III [Salmonella enterica].	29.00	562	370	14	7	552	4	552	1e-64	236
tr:W1XDJ4_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	29.06	561	369	14	8	552	5	552	1e-64	235
tr:B7LQ29_ESCF3	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.87	568	375	14	1	552	7	561	1e-64	236
rs:WP_014391307	DNA topoisomerase III [Pasteurella multocida].	30.10	588	359	20	8	559	5	576	1e-64	235
rs:WP_001235842	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	1e-64	236
rs:WP_036509820	DNA topoisomerase III [Nitrincola sp. AK23].	27.82	611	398	17	8	593	5	597	1e-64	235
rs:WP_001373800	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	1e-64	236
tr:A0A090NLN2_SHIDY	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.87	568	375	14	1	552	17	571	1e-64	236
rs:WP_037005304	DNA topoisomerase, partial [Pseudomonas stutzeri].	30.49	574	350	14	8	555	5	555	1e-64	235
rs:WP_043000912	MULTISPECIES: DNA topoisomerase III [Citrobacter].	29.18	562	369	14	7	552	4	552	1e-64	235
rs:WP_008538783	DNA topoisomerase III [Megamonas funiformis].	31.55	561	325	13	8	531	5	543	1e-64	238
rs:WP_032181066	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	1e-64	235
rs:WP_017440991	DNA topoisomerase III [Salmonella enterica].	29.00	562	370	14	7	552	4	552	1e-64	235
rs:WP_044327842	DNA topoisomerase III [Citrobacter amalonaticus].	29.18	562	369	14	7	552	4	552	1e-64	235
rs:WP_024157020	DNA topoisomerase III [Salmonella enterica].	29.00	562	370	14	7	552	4	552	1e-64	235
rs:WP_044942795	DNA topoisomerase III [Flavonifractor plautii].	30.35	626	374	22	5	601	4	596	1e-64	237
rs:WP_014579488	DNA topoisomerase [Marinobacter adhaerens].	30.13	551	342	13	7	530	4	538	1e-64	236
rs:WP_046942476	DNA topoisomerase III [Haemophilus haemolyticus].	28.35	582	374	16	7	559	4	571	1e-64	235
rs:WP_044862052	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-64	235
rs:WP_028761026	DNA topoisomerase III [Shewanella putrefaciens].	28.78	629	385	18	8	593	5	613	1e-64	236
rs:WP_007649355	DNA topoisomerase III [Shewanella sp. HN-41].	29.25	629	382	19	8	593	5	613	1e-64	236
rs:WP_001698540	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-64	235
rs:WP_001235817	MULTISPECIES: DNA topoisomerase III [Shigella].	29.00	562	370	14	7	552	4	552	1e-64	235
rs:WP_023662392	DNA topoisomerase III, partial [Pseudomonas taiwanensis].	31.63	449	290	9	7	450	4	440	1e-64	230
rs:WP_020913174	DNA topoisomerase III [Shewanella piezotolerans].	29.08	619	384	19	8	593	5	601	1e-64	235
rs:WP_015263775	DNA topoisomerase III [Desulfitobacterium dichloroeliminans].	29.25	612	373	20	7	593	6	582	1e-64	236
rs:WP_012017079	DNA topoisomerase III [Enterobacter sp. 638].	28.52	575	379	14	8	563	5	566	1e-64	235
rs:WP_011609464	DNA topoisomerase III [Histophilus somni].	30.09	565	352	17	8	548	5	550	1e-64	235
gp:AE014075_2103	DNA topoisomerase III [Escherichia coli CFT073]	28.87	568	375	14	1	552	17	571	1e-64	236
rs:WP_006684866	DNA topoisomerase III [Citrobacter youngae].	29.18	562	369	14	7	552	4	552	1e-64	235
rs:WP_023053285	DNA topoisomerase III [Megasphaera sp. BV3C16-1].	28.87	620	400	15	7	602	4	606	1e-64	236
rs:WP_009624172	DNA topoisomerase III [Desulfosporosinus sp. OT].	29.39	609	375	19	5	590	4	580	1e-64	236
rs:WP_001669743	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-64	235
rs:WP_006011047	DNA topoisomerase III [Glaciecola pallidula].	27.64	615	419	14	8	607	5	608	1e-64	235
rs:WP_001504346	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	1e-64	235
gp:CP000468_1639	DNA topoisomerase III [Escherichia coli APEC O1]	28.87	568	375	14	1	552	16	570	1e-64	235
rs:WP_001140202	DNA topoisomerase III [Bacillus cereus].	31.45	566	336	18	5	548	4	539	1e-64	236
tr:A0A0D5VWU6_XANCI	SubName: Full=DNA topoisomerase III, bacteria and conjugative plasmid {ECO:0000313|EMBL:AJZ66613.1};	33.72	430	260	10	4	424	1	414	1e-64	229
rs:WP_001235841	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-64	235
rs:WP_007958677	DNA topoisomerase III [Pelosinus fermentans].	31.43	544	338	12	7	531	4	531	1e-64	235
rs:WP_023182068	DNA topoisomerase III [Salmonella enterica].	29.00	562	370	14	7	552	4	552	1e-64	235
rs:WP_046123363	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-64	235
rs:WP_001235877	DNA topoisomerase III [Salmonella enterica].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_039627610	DNA topoisomerase III [Vibrio ichthyoenteri].	29.67	573	348	16	7	548	5	553	2e-64	235
rs:WP_032102106	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_005646774	DNA topoisomerase III [Haemophilus haemolyticus].	28.10	580	376	15	8	559	5	571	2e-64	235
rs:WP_001235798	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_044697366	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	2e-64	235
rs:WP_024248223	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_014133159	DNA topoisomerase 3 [Methylomicrobium alcaliphilum].	29.25	547	353	13	7	530	4	539	2e-64	236
rs:WP_042003754	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_023247999	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	2e-64	235
rs:WP_005659784	DNA topoisomerase III [Haemophilus influenzae].	27.71	581	379	15	7	559	4	571	2e-64	235
tr:F4TF90_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.96	556	368	13	1	540	7	551	2e-64	235
rs:WP_001578461	DNA topoisomerase III [Escherichia coli].	29.36	562	368	15	7	552	4	552	2e-64	235
rs:WP_021523123	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_001235782	DNA topoisomerase III [Escherichia sp. TW14182].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_033798013	DNA topoisomerase III [Bacillus mycoides].	30.28	568	336	18	7	548	6	539	2e-64	236
rs:WP_014668193	DNA topoisomerase III [Pasteurella multocida].	30.10	588	359	20	8	559	5	576	2e-64	235
rs:WP_040089757	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_024008877	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	2e-64	235
tr:X7I8G3_CITFR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.87	568	375	14	1	552	10	564	2e-64	235
gp:CP002211_1957	DNA topoisomerase III [Escherichia coli str. 'clone D i2']	28.87	568	375	14	1	552	17	571	2e-64	235
rs:WP_022645779	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_001235794	DNA topoisomerase III [Shigella dysenteriae].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_044332759	DNA topoisomerase III [Haemophilus influenzae].	28.69	582	372	17	7	559	4	571	2e-64	235
rs:WP_020311915	DNA topoisomerase III [Megasphaera sp. NM10].	30.99	555	354	14	5	550	3	537	2e-64	236
rs:WP_036254279	DNA topoisomerase [Methylobacter sp. BBA5.1].	29.83	590	369	14	7	564	4	580	2e-64	235
rs:WP_020454016	DNA topoisomerase III [Enterobacter sp. R4-368].	30.07	582	363	18	7	563	4	566	2e-64	235
rs:WP_001702636	DNA topoisomerase 3 [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_001235779	DNA topoisomerase 3 [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_001235777	DNA topoisomerase III [Shigella sonnei].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_032225326	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_001235834	DNA topoisomerase III [Shigella sonnei].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_001235810	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_039234965	DNA topoisomerase III [Bacillus thermotolerans].	31.13	559	343	17	3	548	2	531	2e-64	236
rs:WP_001235821	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_016234421	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_011272053	DNA topoisomerase III [Haemophilus influenzae].	28.69	582	372	17	7	559	4	571	2e-64	234
rs:WP_032256164	DNA topoisomerase III [Escherichia coli].	28.83	562	371	13	7	552	4	552	2e-64	235
rs:WP_045762245	DNA topoisomerase III [Xanthomonas albilineans].	29.10	543	348	13	8	531	5	529	2e-64	236
rs:WP_006942369	DNA topoisomerase [Megasphaera micronuciformis].	30.58	569	357	12	4	552	1	551	2e-64	236
rs:WP_023397678	DNA topoisomerase III [Pseudoalteromonas luteoviolacea].	29.15	597	387	16	8	583	5	586	2e-64	234
rs:WP_032358600	DNA topoisomerase 3 [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	235
rs:WP_021549854	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_001235818	DNA topoisomerase III [Escherichia coli].	29.18	562	369	14	7	552	4	552	2e-64	234
rs:WP_001357807	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_001235809	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_011866096	DNA topoisomerase III [Shewanella loihica].	30.09	565	357	14	8	548	5	555	2e-64	235
rs:WP_001515429	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_033548758	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_042025194	DNA topoisomerase III [Aeromonas enteropelogenes].	30.94	543	342	14	7	530	4	532	2e-64	234
rs:WP_006691865	topoisomerase III [Selenomonas infelix].	29.22	599	383	17	7	580	4	586	2e-64	236
rs:WP_021018801	DNA topoisomerase III [Vibrio gazogenes].	29.39	626	382	20	8	601	6	603	2e-64	234
rs:WP_032314111	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_001235822	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_042039942	DNA topoisomerase III [Aeromonas rivuli].	28.27	619	400	17	7	603	4	600	2e-64	235
rs:WP_039059888	DNA topoisomerase III [Shigella flexneri].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_001235795	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_001587134	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_039025772	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_025745153	DNA topoisomerase III [Shigella flexneri].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_001602679	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_001235808	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_010302694	DNA topoisomerase III [Kurthia sp. JC8E].	31.57	567	341	19	1	548	1	539	2e-64	236
rs:WP_001235826	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_006879407	DNA topoisomerase III [Vibrio brasiliensis].	29.13	563	364	14	7	548	5	553	2e-64	234
rs:WP_001235825	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
tr:A0A029LLV7_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.00	562	370	14	7	552	2	550	2e-64	234
rs:WP_001519770	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_038340935	DNA topoisomerase 3 [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_001235813	DNA topoisomerase III [Shigella flexneri].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_012154870	DNA topoisomerase III [Shewanella pealeana].	30.78	575	344	18	8	548	5	559	2e-64	235
rs:WP_001235839	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	2e-64	234
rs:WP_001235838	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_021574631	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_016158144	MULTISPECIES: DNA topoisomerase III [Escherichia].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_033869912	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_001235840	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
tr:K1YUA4_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.96	533	348	10	3	530	2	519	2e-64	237
rs:WP_032171379	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_044864258	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_045721498	DNA topoisomerase III, partial [Salmonella enterica].	28.83	562	371	14	7	552	4	552	2e-64	234
rs:WP_014448815	DNA topoisomerase III [Leptospirillum ferrooxidans].	30.88	638	377	21	8	604	5	619	2e-64	236
rs:WP_024239616	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_001235884	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_020933262	conjugal transfer protein TraE, DNA topoisomerase III [Cycloclasticus zancles].	30.31	551	341	13	7	530	4	538	2e-64	235
rs:WP_003904754	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_001235811	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_001618284	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	2e-64	234
rs:WP_001235824	MULTISPECIES: DNA topoisomerase III [Escherichia].	29.00	562	370	14	7	552	4	552	2e-64	234
rs:WP_001235806	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_024209137	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001235819	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001559227	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001235799	DNA topoisomerase III [Shigella dysenteriae].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001337807	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_035196071	DNA topoisomerase III [Bacillus azotoformans].	30.89	573	332	19	5	548	4	541	3e-64	236
rs:WP_001235807	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_046083510	DNA topoisomerase III [Escherichia fergusonii].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_034173447	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
tr:A0A070TKB5_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.00	562	370	14	7	552	2	550	3e-64	234
rs:WP_032179590	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001235820	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_024216553	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_046077495	DNA topoisomerase III [Escherichia fergusonii].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001621484	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001549282	DNA topoisomerase 3 [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_033557449	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_032941785	DNA topoisomerase III [Citrobacter sp. 30_2].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001682942	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_040037004	DNA topoisomerase III [Bacillaceae bacterium MTCC 10057].	31.13	559	343	17	3	548	2	531	3e-64	236
rs:WP_032207849	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
tr:Q0T4X0_SHIF8	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.00	562	370	14	7	552	23	571	3e-64	234
rs:WP_044712175	DNA topoisomerase III [Citrobacter freundii].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001552958	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001748363	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	3e-64	234
rs:WP_001235805	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_016240855	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_009440429	DNA topoisomerase [Selenomonas sp. oral taxon 138].	27.70	610	396	15	8	588	5	598	3e-64	235
rs:WP_044804532	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001235831	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_032236924	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001235793	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_024025285	DNA topoisomerase III [Marinomonas profundimaris].	29.06	561	366	12	8	548	5	553	3e-64	234
rs:WP_005696836	DNA topoisomerase III [Haemophilus parainfluenzae].	27.74	620	393	17	7	602	4	592	3e-64	234
rs:WP_044865123	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_024242534	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001520656	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_040078861	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_032141851	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_016245359	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001760094	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_032286490	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_021530492	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001235823	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_021707943	DNA topoisomerase III [Vibrio azureus].	30.14	564	357	15	7	548	5	553	3e-64	234
rs:WP_038349224	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_021571873	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001235802	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001235796	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
sp:TOP3_ECOLI	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_040084318	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_045852115	DNA topoisomerase III [Domibacillus enclensis].	31.03	564	341	17	5	548	4	539	3e-64	236
rs:WP_032264420	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001235801	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_033885626	DNA topoisomerase 3 [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_023154312	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_038179981	DNA topoisomerase III [Vibrio rhizosphaerae].	29.30	628	382	21	8	601	6	605	3e-64	234
rs:WP_042203675	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_021657564	DNA topoisomerase [Clostridiales bacterium oral taxon 876].	30.51	613	372	21	1	590	1	582	3e-64	236
tr:G2AVN2_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.00	562	370	14	7	552	2	550	3e-64	234
rs:WP_001235803	DNA topoisomerase 3 [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001400432	DNA topoisomerase 3 [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_023213983	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	3e-64	234
rs:WP_017842783	DNA topoisomerase [Methylomicrobium buryatense].	29.43	547	352	13	7	530	4	539	3e-64	235
rs:WP_021518430	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_044696303	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_032205278	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001610217	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001468817	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
tr:X7HRM9_CITFR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.87	568	375	14	1	552	10	564	3e-64	234
rs:WP_001468051	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_005662588	DNA topoisomerase III [Haemophilus influenzae].	28.69	582	372	17	7	559	4	571	3e-64	234
rs:WP_032214108	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001235843	DNA topoisomerase III [Shigella dysenteriae].	29.00	562	370	14	7	552	4	552	3e-64	234
rs:WP_001235872	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	4e-64	234
rs:WP_038518007	DNA topoisomerase III, partial [Gilliamella apicola].	29.60	571	365	15	3	549	6	563	4e-64	233
rs:WP_005762746	DNA topoisomerase III [Pasteurella dagmatis].	29.59	588	362	18	8	559	5	576	4e-64	234
rs:WP_046950329	DNA topoisomerase III [Haemophilus haemolyticus].	28.92	581	370	17	8	559	5	571	4e-64	234
rs:WP_022227915	DNA topoisomerase [Megamonas funiformis CAG:377].	31.58	551	338	12	8	531	5	543	4e-64	236
rs:WP_001405289	DNA topoisomerase 3 [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_024221941	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_001569929	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_001461041	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_001235846	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_001235844	DNA topoisomerase 3 [Shigella boydii].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_037072304	DNA topoisomerase III [Psychromonas arctica].	29.46	611	399	15	8	602	5	599	4e-64	234
rs:WP_009728377	DNA topoisomerase III [Selenomonas sp. F0473].	27.41	613	398	16	8	590	5	600	4e-64	235
rs:WP_033552723	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_001235776	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_042782438	DNA topoisomerase III, partial [Salmonella enterica].	28.83	562	371	14	7	552	4	552	4e-64	234
rs:WP_001544610	DNA topoisomerase III [Escherichia coli].	28.65	562	372	14	7	552	4	552	4e-64	234
rs:WP_001524791	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_039066058	DNA topoisomerase III [Shigella flexneri].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_032162751	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_024169425	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_001743829	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_001235868	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	4e-64	234
rs:WP_001235867	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	4e-64	234
rs:WP_001235784	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
tr:X2H3M2_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.60	571	365	15	3	549	6	563	4e-64	233
rs:WP_001235874	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	4e-64	234
rs:WP_001235873	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	4e-64	234
rs:WP_001235847	DNA topoisomerase III [Escherichia fergusonii].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_038988777	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_001480500	DNA topoisomerase III [Escherichia coli].	28.65	562	372	14	7	552	4	552	4e-64	234
rs:WP_036153519	DNA topoisomerase III [Lysinibacillus odysseyi].	30.49	574	327	18	7	548	6	539	4e-64	235
rs:WP_001235791	MULTISPECIES: DNA topoisomerase III [Escherichia].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_001332112	MULTISPECIES: DNA topoisomerase III [Escherichia].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_033545713	DNA topoisomerase 3 [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_001235789	DNA topoisomerase 3 [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_020231706	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_046339371	DNA topoisomerase III [Pasteurella multocida].	29.20	589	365	18	7	559	4	576	4e-64	234
rs:WP_042083422	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_001592093	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_042024539	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
gp:CP007371_1649	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Enteritidis str.]	28.83	562	371	14	7	552	4	552	4e-64	234
rs:WP_042601082	DNA topoisomerase III [Haemophilus influenzae].	28.69	582	372	17	7	559	4	571	4e-64	234
rs:WP_001235875	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	4e-64	234
rs:WP_001235804	MULTISPECIES: DNA topoisomerase III [Escherichia].	29.00	562	370	14	7	552	4	552	4e-64	234
tr:F4SYZ0_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.70	568	376	14	1	552	7	561	4e-64	234
rs:WP_042594782	DNA topoisomerase III [Haemophilus influenzae].	28.69	582	372	17	7	559	4	571	4e-64	234
rs:WP_001235866	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	4e-64	234
rs:WP_001235863	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	4e-64	234
rs:WP_001235871	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	4e-64	234
rs:WP_032303179	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_001235845	MULTISPECIES: DNA topoisomerase III [Shigella].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_023202067	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	4e-64	234
rs:WP_023194085	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	4e-64	234
rs:WP_001235816	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_001235862	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	4e-64	234
rs:WP_021540324	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	4e-64	234
rs:WP_040376372	DNA topoisomerase III [Bacillus psychrosaccharolyticus].	30.93	569	335	18	5	548	4	539	5e-64	235
rs:WP_032209748	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	5e-64	234
rs:WP_032229490	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	5e-64	234
rs:WP_027889424	DNA topoisomerase [Megamonas hypermegale].	30.26	575	350	15	8	550	5	560	5e-64	236
rs:WP_020898703	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	5e-64	234
rs:WP_023230805	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	5e-64	234
rs:WP_024229705	DNA topoisomerase III [Escherichia coli].	28.65	562	372	14	7	552	4	552	5e-64	234
rs:WP_036117504	DNA topoisomerase III [Lysinibacillus sphaericus].	30.39	566	343	18	5	548	4	540	5e-64	235
rs:WP_032331693	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	5e-64	234
tr:A9N283_SALPB	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.83	562	371	14	7	552	10	558	5e-64	234
rs:WP_001235860	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	5e-64	234
rs:WP_031565776	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	5e-64	234
rs:WP_001235861	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	5e-64	234
rs:WP_004095637	DNA topoisomerase III, partial [Acetonema longum].	30.49	551	358	8	8	544	5	544	5e-64	233
rs:WP_042644457	DNA topoisomerase III [Aeromonas eucrenophila].	30.14	564	355	16	7	549	4	549	5e-64	234
rs:WP_023205568	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	5e-64	233
rs:WP_032325498	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	5e-64	234
rs:WP_034946247	DNA topoisomerase III, partial [Gilliamella apicola].	29.07	571	369	13	3	549	6	564	5e-64	233
rs:WP_001235833	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	5e-64	234
rs:WP_001592585	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	5e-64	234
rs:WP_011264006	DNA topoisomerase III [Aliivibrio fischeri].	31.43	544	333	15	8	533	5	526	5e-64	234
rs:WP_010676165	DNA topoisomerase [Aeromonas caviae].	30.40	546	347	11	7	530	4	538	5e-64	234
rs:WP_043953786	DNA topoisomerase III [Enterobacter sp. YD4].	29.90	582	364	18	7	563	4	566	5e-64	233
rs:WP_010618764	DNA topoisomerase III [Plautia stali symbiont].	30.60	549	336	17	7	530	4	532	5e-64	233
sp:TOP3_SALTY	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	28.83	562	371	14	7	552	4	552	5e-64	233
rs:WP_001538825	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	5e-64	233
rs:WP_001537001	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	5e-64	234
rs:WP_033864034	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	33.05	463	276	11	114	552	1	453	5e-64	232
tr:H7E4P1_SALHO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.65	562	372	14	7	552	13	561	5e-64	234
rs:WP_025210557	DNA topoisomerase III [Escherichia coli].	28.65	562	372	14	7	552	4	552	5e-64	233
rs:WP_038999926	DNA topoisomerase III [Escherichia coli].	28.83	562	371	13	7	552	4	552	5e-64	233
gp:CP007348_1716	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Enteritidis str.]	28.83	562	371	14	7	552	4	552	5e-64	233
rs:WP_002115767	DNA topoisomerase III [Bacillus cereus].	31.56	564	334	19	7	548	6	539	5e-64	235
rs:WP_026771933	DNA topoisomerase III [Sediminibacillus halophilus].	31.46	553	325	18	3	532	2	523	5e-64	235
rs:WP_017635824	DNA topoisomerase III [Vibrio sp. 712i1].	30.32	564	356	15	7	548	5	553	5e-64	233
rs:WP_032180754	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	5e-64	233
tr:G5LA33_SALET	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.83	562	371	14	7	552	4	552	6e-64	233
gp:CP007344_1434	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Enteritidis str.]	28.83	562	371	14	7	552	4	552	6e-64	233
rs:WP_001140201	DNA topoisomerase III [Bacillus cereus].	30.77	572	332	17	5	548	4	539	6e-64	235
rs:WP_024797455	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	6e-64	233
rs:WP_001235780	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	6e-64	233
tr:F9ZPH5_ACICS	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.74	575	358	17	7	559	2	552	6e-64	234
rs:WP_033865488	DNA topoisomerase III [Escherichia coli].	28.83	562	371	13	7	552	4	552	6e-64	233
rs:WP_001529235	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	6e-64	233
rs:WP_001235864	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	6e-64	233
tr:R8X2E9_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.70	568	376	14	1	552	10	564	6e-64	233
rs:WP_001235876	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	6e-64	233
rs:WP_041635735	DNA topoisomerase III [Acidithiobacillus caldus].	29.74	575	358	17	7	559	4	554	6e-64	234
rs:WP_001235880	DNA topoisomerase III [Salmonella enterica].	28.65	562	372	14	7	552	4	552	6e-64	233
rs:WP_001235859	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	6e-64	233
tr:V2C251_SALET	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.91	550	364	13	7	540	4	542	6e-64	232
rs:WP_001235815	DNA topoisomerase III [Shigella flexneri].	29.00	562	370	14	7	552	4	552	6e-64	233
rs:WP_033907348	DNA topoisomerase III [Vibrio sp. OY15].	30.32	564	356	15	7	548	5	553	6e-64	233
rs:WP_021552583	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	6e-64	233
rs:WP_005298337	DNA topoisomerase III [Photobacterium damselae].	30.62	565	359	14	8	552	6	557	6e-64	233
tr:A0A080LLZ6_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.07	571	369	13	3	549	6	564	6e-64	233
rs:WP_032323149	DNA topoisomerase III [Escherichia coli].	28.83	562	371	13	7	552	4	552	6e-64	233
tr:G5RGI2_SALET	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.83	562	371	14	7	552	4	552	6e-64	234
rs:WP_001363417	DNA topoisomerase III [Escherichia coli].	28.83	562	371	13	7	552	4	552	7e-64	233
rs:WP_042947452	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	7e-64	233
rs:WP_033559292	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	7e-64	233
rs:WP_010094284	DNA topoisomerase III [Ornithinibacillus scapharcae].	31.05	554	339	16	3	539	2	529	7e-64	234
rs:WP_028768377	DNA topoisomerase III [Shewanella fidelis].	30.92	579	348	18	8	553	5	564	7e-64	234
rs:WP_023216208	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	7e-64	233
rs:WP_021542329	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	7e-64	233
rs:WP_034456056	DNA topoisomerase III [Buttiauxella agrestis].	28.65	562	372	14	7	552	4	552	7e-64	233
rs:WP_041409827	DNA topoisomerase III [Shewanella amazonensis].	27.65	622	396	14	8	602	5	599	7e-64	233
rs:WP_046218684	DNA topoisomerase III [Photobacterium halotolerans].	29.03	558	367	12	8	548	6	551	7e-64	233
rs:WP_001718384	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	8e-64	233
tr:Q57PY5_SALCH	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.83	562	371	14	7	552	23	571	8e-64	233
rs:WP_033560856	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	8e-64	233
tr:A0A064E136_CITFR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.70	568	376	14	1	552	10	564	8e-64	233
rs:WP_044700023	DNA topoisomerase III [Citrobacter freundii].	29.00	562	370	14	7	552	4	552	8e-64	233
rs:WP_003846640	DNA topoisomerase III [Citrobacter freundii].	29.00	562	370	14	7	552	4	552	8e-64	233
rs:WP_008606329	DNA topoisomerase III [Alishewanella aestuarii].	28.62	566	368	12	8	549	5	558	8e-64	233
tr:F9S2S7_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.80	565	352	16	7	548	16	564	8e-64	233
rs:WP_001235812	DNA topoisomerase III [Escherichia coli].	29.09	550	363	13	7	540	4	542	8e-64	233
rs:WP_040647434	DNA topoisomerase III [Pseudoflavonifractor capillosus].	30.00	590	342	18	3	559	2	553	8e-64	234
rs:WP_038669482	DNA topoisomerase III, partial [Sodalis praecaptivus].	28.62	566	367	14	7	552	4	552	8e-64	233
rs:WP_032153052	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	8e-64	233
rs:WP_008456652	DNA topoisomerase III [Enterobacter sp. Ag1].	28.82	576	378	14	7	563	4	566	8e-64	233
rs:WP_042658661	DNA topoisomerase [Aeromonas allosaccharophila].	30.28	545	347	11	8	530	5	538	8e-64	234
rs:WP_023233854	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	8e-64	233
rs:WP_015924446	DNA topoisomerase III [[Clostridium] cellulolyticum].	29.40	619	389	16	3	603	2	590	8e-64	234
rs:WP_001235778	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	8e-64	233
rs:WP_032943124	DNA topoisomerase III [Citrobacter freundii].	29.00	562	370	14	7	552	4	552	8e-64	233
rs:WP_001235829	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	8e-64	233
rs:WP_025757480	DNA topoisomerase III [Shigella flexneri].	29.00	562	370	14	7	552	4	552	8e-64	233
rs:WP_039948979	DNA topoisomerase III [Vibrio ichthyoenteri].	30.80	565	352	16	7	548	5	553	8e-64	233
rs:WP_039482952	DNA topoisomerase III [Vibrio sinaloensis].	30.09	565	356	17	7	548	5	553	9e-64	233
rs:WP_032934436	DNA topoisomerase III [Citrobacter freundii].	29.00	562	370	14	7	552	4	552	9e-64	233
rs:WP_032257590	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	9e-64	233
rs:WP_001507459	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	9e-64	233
rs:WP_023211957	DNA topoisomerase III [Salmonella enterica].	29.00	562	370	14	7	552	4	552	9e-64	233
rs:WP_006005546	DNA topoisomerase III [Glaciecola punicea].	28.78	615	412	14	8	607	5	608	9e-64	233
rs:WP_003030667	MULTISPECIES: DNA topoisomerase III [Citrobacter].	29.00	562	370	14	7	552	4	552	9e-64	233
rs:WP_032949103	DNA topoisomerase III [Citrobacter freundii].	29.00	562	370	14	7	552	4	552	9e-64	233
rs:WP_040234617	DNA topoisomerase III [Shigella flexneri].	29.00	562	370	14	7	552	4	552	9e-64	233
rs:WP_038213471	DNA topoisomerase III [Vibrio variabilis].	29.91	565	357	17	7	548	5	553	9e-64	233
rs:WP_001235790	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	9e-64	233
rs:WP_032936119	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-63	233
rs:WP_001235855	DNA topoisomerase III [Salmonella enterica].	28.65	562	372	13	7	552	4	552	1e-63	233
rs:WP_001235781	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-63	233
rs:WP_045146800	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	1e-63	233
rs:WP_021022293	DNA topoisomerase III [Salinivibrio costicola].	28.98	559	365	14	7	548	5	548	1e-63	233
rs:WP_022373687	DNA topoisomerase III [Sutterella sp. CAG:397].	29.65	634	367	19	7	587	4	611	1e-63	232
rs:WP_001235785	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-63	233
rs:WP_024224548	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	1e-63	233
rs:WP_001674355	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	1e-63	233
rs:WP_031943161	TraE DNA topoisomerase [uncultured bacterium].	30.43	575	351	14	7	555	4	555	1e-63	234
rs:WP_001403074	DNA topoisomerase 3 [Escherichia coli].	28.83	562	371	14	7	552	4	552	1e-63	233
rs:WP_026574293	DNA topoisomerase III [Bacillus sp. UNC438CL73TsuS30].	31.03	564	341	17	5	548	4	539	1e-63	234
rs:WP_032201055	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-63	233
rs:WP_001235797	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	1e-63	233
tr:A6NZE3_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.00	590	342	18	3	559	5	556	1e-63	234
rs:WP_012774824	DNA topoisomerase III [Photobacterium damselae].	29.56	548	349	11	7	530	4	538	1e-63	233
rs:WP_033092471	DNA topoisomerase III [Colwellia psychrerythraea].	30.59	572	350	19	8	548	5	560	1e-63	233
rs:WP_016236697	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-63	233
rs:WP_038391157	DNA topoisomerase III [Salmonella bongori].	28.65	562	372	14	7	552	4	552	1e-63	232
rs:WP_020244836	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-63	233
rs:WP_032224183	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	1e-63	233
rs:WP_041342545	DNA topoisomerase III [Marinobacter similis].	28.44	545	357	12	8	530	5	538	1e-63	234
rs:WP_046081472	DNA topoisomerase III [Escherichia fergusonii].	29.00	562	370	14	7	552	4	552	1e-63	233
rs:WP_042319450	DNA topoisomerase III [Citrobacter farmeri].	28.83	562	371	14	7	552	4	552	1e-63	233
rs:WP_039058176	DNA topoisomerase III [Enterobacter sp. Bisph1].	29.90	582	364	18	7	563	4	566	1e-63	233
rs:WP_005656475	DNA topoisomerase III [Haemophilus influenzae].	27.54	581	380	15	7	559	4	571	1e-63	233
tr:G5R128_SALSE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.83	562	371	14	7	552	4	552	1e-63	233
rs:WP_012055035	DNA topoisomerase III [Haemophilus influenzae].	28.69	582	372	17	7	559	4	571	1e-63	233
rs:WP_001235878	DNA topoisomerase III [Salmonella enterica].	28.83	562	371	14	7	552	4	552	1e-63	233
rs:WP_007019943	DNA topoisomerase III [Neptuniibacter caesariensis].	29.08	557	368	12	8	549	5	549	1e-63	232
rs:WP_027349624	DNA topoisomerase III [Halotalea alkalilenta].	27.24	569	374	13	7	548	4	559	1e-63	233
tr:S6JIF2_PSEST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.43	575	351	14	7	555	4	555	1e-63	234
rs:WP_021573593	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-63	233
rs:WP_046939870	DNA topoisomerase III [Haemophilus haemolyticus].	28.23	581	374	16	8	559	5	571	1e-63	233
rs:WP_016192491	DNA topoisomerase III [Erwinia tracheiphila].	29.36	545	350	13	7	531	4	533	1e-63	232
rs:WP_042923338	DNA topoisomerase [Pseudomonas chloritidismutans].	29.67	573	343	16	8	532	5	565	1e-63	234
rs:WP_003655601	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-63	233
rs:WP_001556646	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	1e-63	233
rs:WP_023655212	DNA topoisomerase III [Erwinia piriflorinigrans].	29.72	545	348	13	7	531	4	533	1e-63	232
rs:WP_012986588	DNA topoisomerase III [Listeria seeligeri].	30.66	623	370	21	5	606	4	585	1e-63	234
rs:WP_001687610	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-63	233
rs:WP_036074259	DNA topoisomerase III [Listeria aquatica].	30.27	555	344	14	5	548	4	526	1e-63	234
tr:A1S7J4_SHEAM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.65	622	396	14	8	602	29	623	1e-63	233
rs:WP_024249166	DNA topoisomerase III [Shigella sonnei].	28.83	562	371	14	7	552	4	552	1e-63	232
rs:WP_005698708	DNA topoisomerase III [Haemophilus parainfluenzae].	27.58	620	394	17	7	602	4	592	1e-63	232
rs:WP_003329635	DNA topoisomerase III [Bacillus azotoformans].	30.30	571	338	17	5	548	4	541	1e-63	234
rs:WP_001235775	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	1e-63	232
rs:WP_044811103	DNA topoisomerase III [Salmonella enterica].	28.90	564	368	15	7	552	4	552	1e-63	232
tr:W0HXD6_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.47	562	373	13	7	552	4	552	2e-63	232
rs:WP_001140200	DNA topoisomerase III [Bacillus thuringiensis].	30.59	572	333	17	5	548	4	539	2e-63	234
rs:WP_001235881	DNA topoisomerase III [Salmonella enterica].	28.65	562	372	14	7	552	4	552	2e-63	232
rs:WP_032947018	DNA topoisomerase III [Citrobacter sp. KTE151].	28.83	562	371	14	7	552	4	552	2e-63	232
rs:WP_044191484	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	2e-63	232
rs:WP_014967282	DNA topoisomerase III [Gottschalkia acidurici].	31.45	566	340	18	3	548	2	539	2e-63	234
rs:WP_046288283	DNA topoisomerase III [Pantoea sp. 3.5.1].	28.32	558	371	14	7	548	4	548	2e-63	232
rs:WP_038871241	DNA topoisomerase III [Vibrio jasicida].	29.79	564	359	15	7	548	5	553	2e-63	232
rs:WP_002169258	DNA topoisomerase III [Bacillus cereus].	30.31	574	328	18	7	548	6	539	2e-63	233
rs:WP_025760919	DNA topoisomerase III [Shigella flexneri].	29.00	562	370	14	7	552	4	552	2e-63	232
rs:WP_046324898	DNA topoisomerase III [Listeria seeligeri].	30.50	623	371	21	5	606	4	585	2e-63	233
rs:WP_042287548	DNA topoisomerase III [Citrobacter sedlakii].	28.83	562	371	14	7	552	4	552	2e-63	232
rs:WP_033557767	DNA topoisomerase [Escherichia coli].	29.06	585	382	12	4	566	1	574	2e-63	233
rs:WP_021556882	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	2e-63	232
rs:WP_046275888	DNA topoisomerase III [Citrobacter amalonaticus].	29.00	562	370	14	7	552	4	552	2e-63	232
rs:WP_001235786	DNA topoisomerase III [Shigella boydii].	29.00	562	370	14	7	552	4	552	2e-63	232
rs:WP_036097359	DNA topoisomerase III [Listeria floridensis].	30.98	539	331	13	5	532	4	512	2e-63	233
rs:WP_038133918	DNA topoisomerase III [Vibrio caribbeanicus].	29.49	573	349	16	7	548	5	553	2e-63	232
rs:WP_005380714	DNA topoisomerase III [Vibrio alginolyticus].	30.14	564	357	15	7	548	5	553	2e-63	232
rs:WP_001478208	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	2e-63	232
rs:WP_001427702	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	2e-63	232
rs:WP_036729055	DNA topoisomerase III [Peptoniphilus sp. ChDC B134].	30.34	557	345	16	7	549	6	533	2e-63	233
rs:WP_008077959	DNA topoisomerase III [Vibrio sinaloensis].	29.91	565	357	16	7	548	5	553	2e-63	232
rs:WP_043016627	DNA topoisomerase III [Citrobacter freundii].	28.83	562	371	14	7	552	4	552	2e-63	232
rs:WP_019076618	DNA topoisomerase III [Citrobacter sp. KTE32].	28.83	562	371	14	7	552	4	552	2e-63	232
rs:WP_042060564	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	2e-63	232
rs:WP_001235830	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	2e-63	232
rs:WP_016103242	DNA topoisomerase 3 [Bacillus cereus].	30.14	574	329	19	7	548	6	539	2e-63	233
rs:WP_016248644	MULTISPECIES: DNA topoisomerase III [Escherichia].	28.83	562	371	14	7	552	4	552	2e-63	232
rs:WP_020844018	DNA topoisomerase III [Salmonella bongori].	28.65	562	372	14	7	552	4	552	2e-63	231
rs:WP_005593919	DNA topoisomerase III [Vibrio scophthalmi].	30.14	564	357	15	7	548	5	553	2e-63	232
rs:WP_046953220	DNA topoisomerase III [Haemophilus haemolyticus].	28.10	580	376	15	8	559	5	571	2e-63	232
rs:WP_012754023	DNA topoisomerase III [Methylobacterium extorquens].	30.71	560	359	14	7	546	6	556	2e-63	235
rs:WP_045782181	DNA topoisomerase III [Klebsiella michiganensis].	28.65	576	379	14	7	563	4	566	2e-63	232
rs:WP_006556936	DNA topoisomerase III [Veillonella ratti].	28.84	593	357	14	7	550	4	580	2e-63	234
rs:WP_035246216	hypothetical protein, partial [Desulfobulbus mediterraneus].	31.27	534	341	13	5	530	3	518	2e-63	231
rs:WP_047104534	DNA topoisomerase III [Vibrio alginolyticus].	30.14	564	357	15	7	548	5	553	2e-63	232
rs:WP_001600005	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	2e-63	232
rs:WP_001626260	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	2e-63	232
rs:WP_001616960	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	2e-63	232
rs:WP_039020743	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	2e-63	231
rs:WP_034875432	DNA topoisomerase III [Endozoicomonas montiporae].	29.40	585	365	16	7	559	4	572	2e-63	232
tr:A0A023VCL4_CITFR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.52	568	377	14	1	552	10	564	3e-63	232
rs:WP_037352392	DNA topoisomerase [Selenomonas sp. FC4001].	30.05	579	369	15	3	561	2	564	3e-63	233
rs:WP_001479370	DNA topoisomerase III [Escherichia coli].	29.00	562	370	14	7	552	4	552	3e-63	232
rs:WP_001465398	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	3e-63	232
rs:WP_026570896	DNA topoisomerase III [Bacillus sp. NSP22.2].	31.28	553	326	18	3	532	2	523	3e-63	233
rs:WP_004560848	DNA topoisomerase [Lactobacillus delbrueckii].	30.87	622	381	19	5	603	3	598	3e-63	233
rs:WP_039475777	DNA topoisomerase III [Vibrio sinaloensis].	29.32	573	350	16	7	548	5	553	3e-63	232
rs:WP_021510069	DNA topoisomerase III [Pantoea dispersa].	30.18	550	339	16	7	531	4	533	3e-63	231
rs:WP_042606006	DNA topoisomerase III [Vibrio harveyi].	29.79	564	359	15	7	548	5	553	3e-63	232
rs:WP_022746718	DNA topoisomerase 3 [Clostridium saccharobutylicum].	30.29	581	352	17	3	559	2	553	3e-63	233
rs:WP_011544434	TraE DNA topoisomerase [uncultured bacterium].	30.26	575	352	14	7	555	4	555	3e-63	233
rs:WP_003604286	DNA topoisomerase III [Methylobacterium extorquens].	30.71	560	359	14	7	546	6	556	3e-63	235
rs:WP_015840206	DNA topoisomerase III [Pectobacterium carotovorum].	28.99	545	352	13	7	531	4	533	3e-63	231
tr:A0A078LIC9_CITKO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.15	566	364	15	7	552	4	552	3e-63	231
rs:WP_001235883	DNA topoisomerase III [Salmonella bongori].	28.65	562	372	14	7	552	4	552	3e-63	231
rs:WP_042654335	DNA topoisomerase III [Aeromonas encheleia].	28.78	615	398	17	7	601	4	598	3e-63	231
rs:WP_041647363	DNA topoisomerase III, partial [Acidithiobacillus ferrooxidans].	30.12	561	349	15	8	548	5	542	3e-63	231
rs:WP_006714537	DNA topoisomerase III [Vibrio ichthyoenteri].	32.29	576	345	18	8	559	5	559	3e-63	232
rs:WP_038354286	DNA topoisomerase III [Escherichia sp. HT073016].	28.83	562	371	14	7	552	4	552	3e-63	231
rs:WP_032259514	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	3e-63	231
rs:WP_001235787	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	3e-63	231
rs:WP_009222685	DNA topoisomerase III [Peptoniphilus sp. oral taxon 386].	30.34	557	345	16	7	549	6	533	3e-63	233
rs:WP_039302172	DNA topoisomerase III [Cedecea neteri].	28.82	576	378	14	7	563	4	566	3e-63	232
rs:WP_005439724	DNA topoisomerase III [Vibrio harveyi].	29.61	564	360	15	7	548	5	553	3e-63	231
rs:WP_003877739	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	3e-63	231
rs:WP_044177384	DNA topoisomerase III [Enterobacter massiliensis].	29.79	564	355	17	7	548	4	548	3e-63	231
rs:WP_001497630	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	3e-63	231
rs:WP_007151773	DNA topoisomerase III [Marinobacter algicola].	29.72	545	350	12	8	530	5	538	3e-63	233
rs:WP_039473015	DNA topoisomerase III [Pectobacterium carotovorum].	28.81	545	353	13	7	531	4	533	3e-63	231
rs:WP_038206707	DNA topoisomerase III [Vibrio tubiashii].	29.56	565	359	16	7	548	5	553	3e-63	231
rs:WP_017821143	DNA topoisomerase III [Vibrio alginolyticus].	30.14	564	357	15	7	548	5	553	3e-63	231
rs:WP_041057988	DNA topoisomerase III [Vibrio owensii].	29.79	564	359	15	7	548	5	553	3e-63	231
rs:WP_001516287	MULTISPECIES: DNA topoisomerase III [Escherichia].	28.65	562	372	14	7	552	4	552	3e-63	231
rs:WP_024232750	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	3e-63	231
rs:WP_020841080	DNA topoisomerase III [Vibrio parahaemolyticus].	29.43	564	361	15	7	548	5	553	4e-63	231
rs:WP_033791181	DNA topoisomerase III [Pantoea sp. FF5].	29.20	565	357	15	7	548	4	548	4e-63	231
rs:WP_001696283	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	4e-63	231
rs:WP_038396119	DNA topoisomerase III [Salmonella enterica].	28.67	558	369	14	7	548	4	548	4e-63	231
rs:WP_004748460	DNA topoisomerase III [Vibrio tubiashii].	29.56	565	359	16	7	548	5	553	4e-63	231
rs:WP_038473424	DNA topoisomerase III [Cedecea neteri].	28.83	562	371	13	7	552	4	552	4e-63	231
rs:WP_016535970	DNA topoisomerase III [Cedecea davisae].	28.99	576	377	15	7	563	4	566	4e-63	231
rs:WP_004414842	DNA topoisomerase III [Vibrio orientalis].	29.56	565	359	16	7	548	5	553	4e-63	231
rs:WP_044129469	DNA topoisomerase III [Vibrio parahaemolyticus].	30.14	564	357	15	7	548	5	553	4e-63	231
rs:WP_005384913	DNA topoisomerase III [Vibrio alginolyticus].	30.14	564	357	15	7	548	5	553	4e-63	231
rs:WP_001235832	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	4e-63	231
rs:WP_032290511	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	4e-63	231
rs:WP_042522502	DNA topoisomerase III [Vibrio alginolyticus].	30.14	564	357	15	7	548	5	553	4e-63	231
rs:WP_024173215	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	4e-63	231
rs:WP_045062705	DNA topoisomerase III [Photobacterium leiognathi].	30.48	561	355	16	8	548	6	551	4e-63	231
rs:WP_025622790	DNA topoisomerase III [Vibrio parahaemolyticus].	29.43	564	361	15	7	548	5	553	4e-63	231
rs:WP_005473440	DNA topoisomerase III [Vibrio sp. 16].	29.91	565	357	17	7	548	5	553	4e-63	231
tr:I6HGX2_SHIFL	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.65	562	372	13	7	552	4	552	4e-63	231
rs:WP_001548631	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	4e-63	231
rs:WP_046511331	DNA topoisomerase III [Salinicoccus sp. SV-16].	30.16	567	341	18	5	549	4	537	4e-63	232
rs:WP_018212069	DNA topoisomerase III [Desulfitobacterium hafniense].	28.81	611	377	19	7	593	6	582	4e-63	232
tr:M8T8N0_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.83	562	371	14	7	552	2	550	5e-63	231
rs:WP_003618392	DNA topoisomerase [Lactobacillus delbrueckii].	30.71	622	382	19	5	603	3	598	5e-63	232
rs:WP_009835356	DNA topoisomerase III [Marinomonas sp. MED121].	28.34	561	368	14	8	548	5	551	5e-63	231
rs:WP_041510970	DNA topoisomerase III [Shewanella sp. cp20].	29.31	563	364	14	8	548	5	555	5e-63	231
rs:WP_031575408	DNA topoisomerase III, partial [Acidithiobacillus thiooxidans].	29.75	568	342	17	8	548	5	542	5e-63	231
rs:WP_033962387	DNA topoisomerase [Pseudomonas aeruginosa].	29.49	573	344	16	8	532	5	565	5e-63	232
rs:WP_039489549	DNA topoisomerase III [Pectobacterium carotovorum].	28.81	545	353	13	7	531	4	533	5e-63	231
rs:WP_045405705	DNA topoisomerase III [Vibrio jasicida].	29.61	564	360	15	7	548	5	553	5e-63	231
rs:WP_016506274	DNA topoisomerase III [Salmonella enterica].	28.65	562	372	14	7	552	4	552	5e-63	231
rs:WP_042308879	DNA topoisomerase III [Citrobacter werkmanii].	28.83	562	371	14	7	552	4	552	5e-63	231
rs:WP_044204558	DNA topoisomerase III [Pectobacterium carotovorum].	28.81	545	353	13	7	531	4	533	5e-63	231
rs:WP_045666083	DNA topoisomerase [Pseudomonas sp. BRH_c35].	29.49	573	344	16	8	532	5	565	6e-63	232
rs:WP_002201907	DNA topoisomerase III [Bacillus cereus].	29.81	567	340	18	7	548	6	539	6e-63	232
rs:WP_019382435	DNA topoisomerase III [Bacillus oceanisediminis].	31.14	562	340	17	7	548	6	540	6e-63	232
rs:WP_040886141	DNA topoisomerase III [Marinobacterium stanieri].	30.36	560	355	16	8	548	5	548	6e-63	231
rs:WP_036562672	DNA topoisomerase III, partial [Candidatus Schmidhempelia bombi].	30.00	620	385	20	8	598	5	604	6e-63	230
rs:WP_008813734	DNA topoisomerase III [Hafnia paralvei].	29.30	546	349	15	7	531	4	533	6e-63	230
rs:WP_027406931	DNA topoisomerase [Anaerovibrio sp. RM50].	31.70	571	325	19	8	536	5	552	6e-63	233
rs:WP_024551811	DNA topoisomerase III [Cronobacter helveticus].	27.85	578	381	15	7	563	4	566	6e-63	231
rs:WP_021515047	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	6e-63	231
rs:WP_032176337	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	6e-63	231
rs:WP_025238906	DNA topoisomerase III [Escherichia albertii].	28.52	561	372	14	8	552	5	552	6e-63	231
rs:WP_039611528	DNA topoisomerase III [Pseudoalteromonas luteoviolacea].	29.67	573	353	15	8	553	5	554	6e-63	230
rs:WP_001508687	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	6e-63	231
rs:WP_040233658	DNA topoisomerase III [Citrobacter sp. CIP 55.13].	28.65	562	372	13	7	552	4	552	6e-63	230
rs:WP_039842429	DNA topoisomerase III [Vibrio owensii].	29.61	564	360	15	7	548	5	553	6e-63	231
rs:WP_017548815	DNA topoisomerase III [Salinicoccus carnicancri].	30.35	547	335	15	5	532	4	523	7e-63	232
rs:WP_010197614	DNA topoisomerase III [Bacillus sp. m3-13].	31.14	578	348	20	5	559	4	554	7e-63	232
rs:WP_025556707	DNA topoisomerase III [Vibrio parahaemolyticus].	29.43	564	361	15	7	548	5	553	7e-63	231
rs:WP_012536731	DNA topoisomerase III [Acidithiobacillus ferrooxidans].	30.35	570	336	17	8	548	5	542	7e-63	231
rs:WP_007889711	DNA topoisomerase III [Pantoea sp. GM01].	30.16	547	343	15	7	531	4	533	7e-63	230
rs:WP_024209312	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	7e-63	230
rs:WP_001235856	DNA topoisomerase III [Salmonella enterica].	28.65	562	372	14	7	552	4	552	7e-63	230
rs:WP_029790477	DNA topoisomerase III [Vibrio harveyi].	29.43	564	361	15	7	548	5	553	7e-63	230
rs:WP_009387842	DNA topoisomerase III [Vibrio sp. N418].	29.79	564	359	15	7	548	5	553	7e-63	230
rs:WP_020195690	DNA topoisomerase III [Vibrio owensii].	29.61	564	360	15	7	548	5	553	7e-63	230
rs:WP_009707306	DNA topoisomerase III [Vibrio sp. HENC-03].	29.61	564	360	15	7	548	5	553	7e-63	230
rs:WP_039358423	DNA topoisomerase III [Pectobacterium carotovorum].	28.81	545	353	13	7	531	4	533	8e-63	230
rs:WP_042483778	DNA topoisomerase III [Vibrio diazotrophicus].	27.70	621	404	19	8	603	6	606	8e-63	230
rs:WP_033193536	DNA topoisomerase III, partial [Amphibacillus jilinensis].	32.85	548	316	19	3	532	2	515	8e-63	231
rs:WP_031519835	DNA topoisomerase III [Cronobacter sp. 1383].	29.08	564	367	14	7	552	4	552	8e-63	230
rs:WP_046479673	DNA topoisomerase III [Citrobacter amalonaticus].	28.47	562	373	14	7	552	4	552	8e-63	230
sp:TOP3_SALTI	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	28.65	562	372	14	7	552	4	552	8e-63	230
rs:WP_012765573	MULTISPECIES: DNA topoisomerase III [Dickeya].	28.65	562	364	15	7	548	4	548	9e-63	230
rs:WP_012441306	DNA topoisomerase III [Erwinia tasmaniensis].	29.72	545	348	13	7	531	4	533	9e-63	230
rs:WP_046093421	DNA topoisomerase III [Salmonella enterica].	28.65	562	372	14	7	552	4	552	9e-63	230
rs:WP_023184966	DNA topoisomerase III [Salmonella enterica].	28.65	562	372	14	7	552	4	552	9e-63	230
rs:WP_023179729	DNA topoisomerase III [Salmonella enterica].	28.65	562	372	14	7	552	4	552	9e-63	230
tr:A6W0F1_MARMS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.23	561	365	13	8	548	5	553	9e-63	230
rs:WP_044710862	DNA topoisomerase III [Escherichia coli].	28.52	561	372	14	8	552	5	552	9e-63	230
rs:WP_001235870	DNA topoisomerase III [Salmonella enterica].	28.65	562	372	14	7	552	4	552	9e-63	230
rs:WP_001235854	DNA topoisomerase III [Salmonella enterica].	28.65	562	372	14	7	552	4	552	1e-62	230
rs:WP_027705174	DNA topoisomerase III [Zymobacter palmae].	29.51	566	357	16	8	548	5	553	1e-62	230
rs:WP_047123684	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	1e-62	230
rs:WP_014343684	DNA topoisomerase III [Aliivibrio fischeri].	31.38	580	331	21	4	547	1	549	1e-62	231
tr:B7JBJ6_ACIF2	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.12	561	349	15	8	548	5	542	1e-62	231
rs:WP_029793271	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	1e-62	230
rs:WP_038640087	DNA topoisomerase III [Citrobacter freundii].	28.65	562	372	14	7	552	4	552	1e-62	230
rs:WP_006743281	DNA topoisomerase III [Vibrio sp. Ex25].	30.14	564	357	15	7	548	5	553	1e-62	230
rs:WP_017189344	DNA topoisomerase III [Vibrio harveyi].	29.43	564	361	15	7	548	5	553	1e-62	230
rs:WP_046874516	DNA topoisomerase III [Vibrio alginolyticus].	30.14	564	357	15	7	548	5	553	1e-62	230
rs:WP_008911016	DNA topoisomerase III [Providencia burhodogranariea].	30.44	542	346	14	7	530	4	532	1e-62	230
rs:WP_032203321	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	1e-62	230
rs:WP_001637972	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	1e-62	230
rs:WP_015010818	DNA topoisomerase III [Amphibacillus xylanus].	32.73	556	327	21	1	541	1	524	1e-62	231
rs:WP_003801585	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	1e-62	230
rs:WP_045419892	DNA topoisomerase III [Vibrio jasicida].	29.61	564	360	15	7	548	5	553	1e-62	230
rs:WP_039556869	DNA topoisomerase III [Pectobacterium carotovorum].	28.62	545	354	13	7	531	4	533	1e-62	229
rs:WP_005444645	DNA topoisomerase III [Vibrio harveyi].	29.43	564	361	15	7	548	5	553	1e-62	230
rs:WP_034832080	DNA topoisomerase III [Endozoicomonas numazuensis].	29.54	545	351	14	7	531	4	535	1e-62	229
rs:WP_032989883	DNA topoisomerase III [Cronobacter sakazakii].	28.44	559	369	15	7	548	4	548	1e-62	230
rs:WP_039544674	DNA topoisomerase III [Pectobacterium carotovorum].	28.62	545	354	13	7	531	4	533	1e-62	229
rs:WP_028862617	DNA topoisomerase III [Psychromonas aquimarina].	30.80	539	348	11	8	531	5	533	1e-62	229
rs:WP_039286594	DNA topoisomerase III [Pectobacterium carotovorum].	28.62	545	354	13	7	531	4	533	1e-62	229
rs:WP_039511341	DNA topoisomerase III [Pectobacterium carotovorum].	28.62	545	354	13	7	531	4	533	1e-62	229
rs:WP_022241545	DNA topoisomerase III [Clostridium sp. CAG:413].	31.41	573	330	17	5	550	4	540	1e-62	231
rs:WP_038896082	DNA topoisomerase III [Vibrio owensii].	29.61	564	360	15	7	548	5	553	1e-62	230
rs:WP_042678820	DNA topoisomerase III [Anaerosalibacter sp. ND1].	30.73	563	339	18	7	548	6	538	1e-62	231
rs:WP_042601263	DNA topoisomerase III [Vibrio harveyi].	29.58	568	355	16	7	548	5	553	1e-62	230
rs:WP_039514922	DNA topoisomerase III [Pectobacterium carotovorum].	28.62	545	354	13	7	531	4	533	1e-62	229
rs:WP_005815481	DNA topoisomerase III [Desulfitobacterium hafniense].	28.62	615	373	18	7	593	6	582	1e-62	231
rs:WP_010295239	DNA topoisomerase III [Pectobacterium carotovorum].	28.62	545	354	13	7	531	4	533	1e-62	229
rs:WP_045953833	DNA topoisomerase III [Vibrio sp. S2757].	29.55	555	338	15	7	530	5	537	1e-62	229
rs:WP_039464120	DNA topoisomerase III [Pectobacterium carotovorum].	28.62	545	354	13	7	531	4	533	1e-62	229
gp:CP007354_1499	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Enteritidis str.]	28.47	562	373	14	7	552	4	552	1e-62	229
rs:WP_040032912	DNA topoisomerase III [Pectobacterium carotovorum].	28.62	545	354	13	7	531	4	533	1e-62	229
rs:WP_038625843	DNA topoisomerase III [Pantoea sp. PSNIH2].	28.45	566	368	14	7	552	4	552	1e-62	229
rs:WP_005396516	DNA topoisomerase III [Vibrio alginolyticus].	30.14	564	357	15	7	548	5	553	1e-62	229
rs:WP_039496146	DNA topoisomerase III [Pectobacterium carotovorum].	28.62	545	354	13	7	531	4	533	1e-62	229
rs:WP_039315128	DNA topoisomerase III [Pectobacterium carotovorum].	28.62	545	354	13	7	531	4	533	1e-62	229
rs:WP_027831559	DNA topoisomerase III [Marinobacter sp. HL-58].	29.07	547	351	13	8	530	5	538	1e-62	231
rs:WP_038156149	DNA topoisomerase III [Vibrio sp. B183].	28.90	564	364	15	7	548	5	553	1e-62	229
rs:WP_025218532	DNA topoisomerase III [Lysinibacillus varians].	30.78	562	342	17	7	548	6	540	1e-62	231
rs:WP_040062870	DNA topoisomerase III [Escherichia coli].	28.83	562	371	14	7	552	4	552	1e-62	229
rs:WP_017817824	DNA topoisomerase III [Vibrio harveyi].	29.43	564	361	15	7	548	5	553	1e-62	229
rs:WP_016837347	DNA topoisomerase III [Ureibacillus thermosphaericus].	29.73	565	346	17	5	548	4	538	1e-62	231
rs:WP_001524338	DNA topoisomerase III [Salmonella enterica].	28.65	562	372	14	7	552	4	552	1e-62	229
rs:WP_012101445	DNA topoisomerase III [Clostridium kluyveri].	29.58	578	360	18	1	559	1	550	2e-62	231
rs:WP_039529009	DNA topoisomerase III [Pectobacterium carotovorum].	28.62	545	354	13	7	531	4	533	2e-62	229
rs:WP_012905567	DNA topoisomerase III [Citrobacter rodentium].	28.47	562	373	13	7	552	4	552	2e-62	229
rs:WP_012667948	DNA topoisomerase III [Erwinia pyrifoliae].	29.36	545	350	13	7	531	4	533	2e-62	229
rs:WP_036108821	DNA topoisomerase III, partial [Mangrovibacter sp. MFB070].	28.55	543	357	14	7	531	4	533	2e-62	229
rs:WP_021454915	DNA topoisomerase III [Vibrio coralliilyticus].	28.90	564	364	15	7	548	5	553	2e-62	229
rs:WP_025903047	MULTISPECIES: DNA topoisomerase III [Tatumella].	28.80	566	358	16	7	548	4	548	2e-62	229
tr:A0A061PRR0_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.96	564	358	15	7	548	5	553	2e-62	229
rs:WP_005968748	DNA topoisomerase III [Pectobacterium wasabiae].	28.81	545	353	13	7	531	4	533	2e-62	229
rs:WP_014915327	DNA topoisomerase III [Pectobacterium carotovorum].	28.62	545	354	13	7	531	4	533	2e-62	229
rs:WP_038510307	DNA topoisomerase III [Vibrio coralliilyticus].	28.90	564	364	15	7	548	5	553	2e-62	229
rs:WP_032823989	DNA topoisomerase III [Haemophilus influenzae].	27.76	580	378	15	8	559	5	571	2e-62	229
rs:WP_038674145	DNA topoisomerase [Pelosinus sp. UFO1].	30.76	556	350	11	7	543	4	543	2e-62	229
rs:WP_021771516	DNA topoisomerase [Mitsuokella sp. oral taxon 131].	31.76	551	331	16	8	530	5	538	2e-62	232
rs:WP_045498250	DNA topoisomerase III [Vibrio sp. 151112A].	29.43	564	361	15	7	548	5	553	2e-62	229
rs:WP_038007810	DNA topoisomerase, partial [Sutterella wadsworthensis].	30.51	567	336	14	7	530	4	555	2e-62	229
rs:WP_010561672	DNA topoisomerase III [Pseudoalteromonas spongiae].	30.27	555	361	15	8	548	5	547	2e-62	229
gp:CP007434_1573	DNA topoisomerase III [Salmonella enterica subsp. enterica serovar Enteritidis str.]	28.65	562	372	15	7	552	4	552	2e-62	229
rs:WP_041154903	DNA topoisomerase III [Vibrio mytili].	29.43	564	361	15	7	548	5	553	2e-62	229
rs:WP_021822369	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	2e-62	229
rs:WP_023481300	DNA topoisomerase III [Enterobacter cloacae].	29.33	566	363	15	7	552	4	552	2e-62	229
tr:A0A071LW77_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.55	543	357	14	7	531	4	533	2e-62	229
rs:WP_045973488	DNA topoisomerase III [Xenorhabdus doucetiae].	29.28	543	353	14	7	531	4	533	2e-62	229
rs:WP_039292251	DNA topoisomerase III [Cedecea neteri].	28.47	576	380	14	7	563	4	566	2e-62	229
rs:WP_013439876	DNA topoisomerase [Lactobacillus delbrueckii].	30.71	622	382	19	5	603	3	598	2e-62	230
rs:WP_046174720	DNA topoisomerase III [Domibacillus indicus].	30.82	558	346	18	3	549	2	530	2e-62	230
rs:WP_036849554	DNA topoisomerase III [Photorhabdus temperata].	29.36	545	350	14	7	531	4	533	2e-62	229
rs:WP_036774908	DNA topoisomerase III [Photorhabdus asymbiotica].	29.54	545	349	14	7	531	4	533	2e-62	229
tr:B9E0J7_CLOK1	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.58	578	360	18	1	559	3	552	2e-62	231
rs:WP_032476424	DNA topoisomerase III [Vibrio cholerae].	28.57	567	344	15	8	539	6	546	2e-62	229
rs:WP_038881887	DNA topoisomerase III [Vibrio jasicida].	29.61	564	360	15	7	548	5	553	2e-62	229
rs:WP_045644923	DNA topoisomerase III [Peptococcaceae bacterium BRH_c4b].	29.17	593	354	19	7	563	5	567	2e-62	230
rs:WP_005432974	DNA topoisomerase III [Vibrio campbellii].	29.43	564	361	15	7	548	5	553	2e-62	229
rs:WP_005699835	DNA topoisomerase III [Haemophilus parainfluenzae].	27.42	620	395	17	7	602	4	592	2e-62	229
rs:WP_046885891	DNA topoisomerase III [Enterobacter cloacae].	28.65	576	379	15	7	563	4	566	2e-62	229
rs:WP_001235851	DNA topoisomerase III [Escherichia albertii].	28.52	561	372	14	8	552	5	552	2e-62	229
rs:WP_031612074	DNA topoisomerase III, partial [Salmonella enterica].	29.28	526	345	13	43	552	12	526	2e-62	228
rs:WP_011066983	DNA topoisomerase III [Oceanobacillus iheyensis].	31.94	551	333	19	3	539	2	524	2e-62	230
rs:WP_038859932	DNA topoisomerase III, partial [Cronobacter sakazakii].	28.26	559	370	15	7	548	4	548	2e-62	228
rs:WP_035311086	DNA topoisomerase III [Clostridium sp. HMP27].	29.41	629	383	23	7	606	6	602	2e-62	230
rs:WP_040076043	DNA topoisomerase III [Enterobacteriaceae bacterium ATCC 29904].	28.65	576	379	15	7	563	4	566	2e-62	229
rs:WP_045442006	DNA topoisomerase III [Citrobacter sp. S-77].	28.83	562	371	14	7	552	4	552	2e-62	229
rs:WP_029846690	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	2e-62	229
tr:E6QCV3_9ZZZZ	SubName: Full=Putative DNA topoisomerase III (TopB) {ECO:0000313|EMBL:CBI05029.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI05029.1};	29.75	568	342	17	8	548	5	542	2e-62	229
rs:WP_015945463	DNA topoisomerase III [Desulfitobacterium hafniense].	28.46	615	374	18	7	593	6	582	2e-62	230
rs:WP_009754085	DNA topoisomerase TopB [Selenomonas sp. oral taxon 149].	29.41	561	332	17	8	531	5	538	2e-62	230
rs:WP_039554976	DNA topoisomerase III [Pectobacterium carotovorum].	28.62	545	354	13	7	531	4	533	2e-62	229
tr:K8B175_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.18	562	361	17	7	548	4	548	2e-62	229
tr:A0A0B0HJQ3_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.88	544	313	19	7	537	6	499	3e-62	225
rs:WP_036378381	DNA topoisomerase [Mitsuokella jalaludinii].	30.58	556	337	15	8	530	5	544	3e-62	231
rs:WP_039974109	DNA topoisomerase III [Vibrio jasicida].	29.79	564	359	15	7	548	5	553	3e-62	229
rs:WP_039980581	DNA topoisomerase III [Vibrio sagamiensis].	30.14	564	357	15	7	548	5	553	3e-62	229
rs:WP_004386618	DNA topoisomerase III, partial [Cronobacter sakazakii].	28.26	559	370	15	7	548	4	548	3e-62	228
rs:WP_029864161	DNA topoisomerase III [Vibrio parahaemolyticus].	29.43	564	361	16	7	548	5	553	3e-62	229
rs:WP_029833579	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	3e-62	229
rs:WP_000197429	DNA topoisomerase III [Vibrio cholerae].	28.75	567	343	15	8	539	6	546	3e-62	229
rs:WP_011462224	DNA topoisomerase III [Desulfitobacterium hafniense].	28.62	615	373	18	7	593	6	582	3e-62	230
tr:A0A098B862_DESHA	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.62	615	373	18	7	593	6	582	3e-62	230
rs:WP_025636901	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	3e-62	229
rs:WP_010644027	DNA topoisomerase III [Vibrio campbellii].	29.79	564	359	16	7	548	5	553	3e-62	229
rs:WP_004169946	DNA topoisomerase III [Erwinia amylovora].	29.36	545	350	13	7	531	4	533	3e-62	228
rs:WP_042392964	DNA topoisomerase III [Escherichia vulneris].	29.56	565	355	17	7	548	4	548	3e-62	229
rs:WP_024105857	MULTISPECIES: DNA topoisomerase III [Dickeya].	28.55	564	362	16	7	548	4	548	3e-62	228
rs:WP_036293444	DNA topoisomerase [Methylobacter whittenburyi].	28.65	548	356	13	7	530	4	540	3e-62	229
rs:WP_007469989	DNA topoisomerase III [Photobacterium sp. AK15].	29.75	558	363	14	8	548	6	551	3e-62	229
rs:WP_028129876	DNA topoisomerase [Selenomonas sp. AE3005].	30.32	554	340	14	8	531	5	542	3e-62	231
rs:WP_004093052	DNA topoisomerase III [Hafnia alvei].	29.30	546	349	15	7	531	4	533	3e-62	228
rs:WP_045397957	DNA topoisomerase III [Vibrio sp. 090810a].	29.43	564	361	15	7	548	5	553	3e-62	229
rs:WP_043008804	DNA topoisomerase III [Vibrio coralliilyticus].	28.90	564	364	15	7	548	5	553	3e-62	229
rs:WP_036945020	DNA topoisomerase III [Pseudobacteroides cellulosolvens].	29.96	564	345	17	7	550	6	539	3e-62	230
rs:WP_025611875	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	3e-62	229
rs:WP_005387096	hypothetical protein [Veillonella dispar].	28.16	632	399	17	7	598	4	620	3e-62	231
rs:WP_007893951	DNA topoisomerase III [Cronobacter sakazakii].	28.26	559	370	15	7	548	4	548	3e-62	229
rs:WP_046457683	DNA topoisomerase III [Hafnia alvei].	29.12	546	350	15	7	531	4	533	3e-62	228
rs:WP_009655052	DNA topoisomerase III [Selenomonas sp. FOBRC6].	29.27	550	347	14	8	531	5	538	3e-62	230
rs:WP_040956109	DNA topoisomerase III [Virgibacillus sp. SK37].	30.92	553	336	17	3	538	2	525	3e-62	230
rs:WP_045984985	DNA topoisomerase III [Vibrio coralliilyticus].	28.90	564	364	15	7	548	5	553	3e-62	229
rs:WP_025609941	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	3e-62	229
rs:WP_006305756	DNA topoisomerase TopB [Centipeda periodontii].	28.07	570	367	13	8	550	5	558	3e-62	229
rs:WP_025635400	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	3e-62	229
rs:WP_045604644	DNA topoisomerase III [Vibrio parahaemolyticus].	29.31	563	361	15	8	548	6	553	3e-62	229
rs:WP_025991918	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	31.76	466	287	11	52	498	1	454	3e-62	224
rs:WP_025558293	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	3e-62	229
rs:WP_023585247	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	3e-62	229
tr:A0A0D6ZHR8_LACDE	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:KIY24168.1};	30.71	622	382	19	5	603	3	598	3e-62	229
rs:WP_047354069	DNA topoisomerase III [Enterobacter sp. GN02315].	28.65	576	379	15	7	563	4	566	4e-62	228
rs:WP_045545704	DNA topoisomerase III [Vibrio sp. S512-13].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_012535949	DNA topoisomerase III [Acidithiobacillus ferrooxidans].	29.58	568	343	17	8	548	5	542	4e-62	229
rs:WP_038883834	DNA topoisomerase III [Cronobacter dublinensis].	29.18	562	361	17	7	548	4	548	4e-62	228
rs:WP_024699733	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_045607374	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_033932793	DNA topoisomerase III [Vibrio cholerae].	28.75	567	343	15	8	539	6	546	4e-62	228
rs:WP_010275359	DNA topoisomerase III [Pectobacterium carotovorum].	28.62	545	354	13	7	531	4	533	4e-62	228
rs:WP_045974983	DNA topoisomerase III [Vibrio neptunius].	29.08	564	363	15	7	548	5	553	4e-62	228
tr:T0NZ48_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.71	555	314	22	7	546	5	509	4e-62	225
rs:WP_023169111	DNA topoisomerase III, partial [Salmonella enterica].	29.28	526	345	13	43	552	2	516	4e-62	228
rs:WP_026759425	DNA topoisomerase [Selenomonas ruminantium].	30.20	553	342	13	8	531	5	542	4e-62	231
rs:WP_014729094	DNA topoisomerase III [Cronobacter sakazakii].	28.26	559	370	15	7	548	4	548	4e-62	228
rs:WP_009355184	DNA topoisomerase III [Vibrio sp. RC341].	26.94	631	402	16	7	603	5	610	4e-62	228
rs:WP_036206169	DNA topoisomerase III [Marinobacter sp. MCTG268].	28.78	542	359	11	8	530	5	538	4e-62	229
rs:WP_025587447	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_029854479	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_029807206	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_025499560	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_000197437	DNA topoisomerase III [Vibrio cholerae].	28.92	567	342	16	8	539	6	546	4e-62	228
rs:WP_029827151	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_029845242	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_031815415	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_025505736	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_015964778	DNA topoisomerase III [Enterobacteriaceae bacterium strain FGI 57].	28.80	566	366	14	7	552	4	552	4e-62	228
rs:WP_021147943	DNA topoisomerase III [Veillonella parvula].	28.28	633	397	18	7	598	4	620	4e-62	230
rs:WP_033539187	DNA topoisomerase III [Shewanella sp. ECSMB14101].	29.31	563	364	13	8	548	5	555	4e-62	229
rs:WP_034828805	DNA topoisomerase III [Enterobacter cancerogenus].	29.58	568	359	17	7	552	4	552	4e-62	228
rs:WP_042470619	DNA topoisomerase III [Bacillus sp. FF3].	30.17	580	350	19	5	559	4	553	4e-62	229
rs:WP_045816089	DNA topoisomerase III [Pantoea sp. SM3].	29.58	568	359	17	7	552	4	552	4e-62	228
rs:WP_031851482	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_017447821	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_039344884	DNA topoisomerase III [Pectobacterium carotovorum].	28.81	545	353	13	7	531	4	533	4e-62	228
rs:WP_025546308	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_032475343	DNA topoisomerase III [Vibrio cholerae].	28.60	563	349	15	8	539	6	546	4e-62	228
rs:WP_031382112	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_031856192	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_025529541	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	4e-62	228
rs:WP_013345169	DNA topoisomerase III [Ferrimonas balearica].	30.54	560	355	15	8	549	5	548	5e-62	228
rs:WP_046823179	DNA topoisomerase III [Clostridium sp. JC272].	31.06	602	333	22	5	580	4	549	5e-62	229
rs:WP_006812878	DNA topoisomerase III [Providencia rustigianii].	29.89	542	349	14	7	530	4	532	5e-62	228
rs:WP_025535495	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	5e-62	228
rs:WP_045307963	DNA topoisomerase III [Enterobacter sp. 36796].	28.47	576	380	14	7	563	4	566	5e-62	228
rs:WP_025528100	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	5e-62	228
tr:E5B623_ERWAM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.17	545	351	13	7	531	4	533	5e-62	228
rs:WP_032993914	DNA topoisomerase III [Cronobacter malonaticus].	28.26	559	370	15	7	548	4	548	5e-62	228
rs:WP_029861830	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	5e-62	228
rs:WP_025521195	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	5e-62	228
rs:WP_029815742	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	5e-62	228
rs:WP_025605522	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	5e-62	228
rs:WP_025591399	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	5e-62	228
rs:WP_045588151	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	5e-62	228
rs:WP_045480696	DNA topoisomerase III [Vibrio owensii].	29.43	564	361	15	7	548	5	553	5e-62	228
rs:WP_021449869	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	5e-62	228
rs:WP_014232576	DNA topoisomerase III [Vibrio sp. EJY3].	29.26	564	362	15	7	548	5	553	5e-62	228
rs:WP_038857389	DNA topoisomerase III [Cronobacter universalis].	28.26	559	370	15	7	548	4	548	5e-62	228
rs:WP_039300069	DNA topoisomerase III [Pectobacterium betavasculorum].	28.44	545	355	13	7	531	4	533	5e-62	228
rs:WP_025535135	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	5e-62	228
rs:WP_039029035	DNA topoisomerase III [Leclercia adecarboxylata].	28.29	562	374	13	7	552	4	552	5e-62	228
rs:WP_011045511	DNA topoisomerase III [Colwellia psychrerythraea].	31.12	572	347	20	8	548	5	560	5e-62	228
rs:WP_025553795	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	5e-62	228
rs:WP_014795822	DNA topoisomerase III [Desulfitobacterium dehalogenans].	29.61	564	348	16	7	550	6	540	5e-62	229
rs:WP_040045076	DNA topoisomerase III [Hafnia alvei].	29.12	546	350	15	7	531	4	533	5e-62	228
rs:WP_020838689	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	5e-62	228
tr:A0A080KKI8_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.60	571	365	16	3	549	6	563	5e-62	228
rs:WP_038172978	DNA topoisomerase III [Vibrio pacinii].	29.14	573	351	16	7	548	5	553	5e-62	228
tr:K5V6Y2_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.26	564	362	15	7	548	5	553	5e-62	228
rs:WP_025631592	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	5e-62	228
rs:WP_000197430	DNA topoisomerase III [Vibrio albensis].	28.57	567	344	16	8	539	6	546	5e-62	228
rs:WP_002440314	DNA topoisomerase III [Shimwellia blattae].	28.90	564	366	16	8	552	5	552	5e-62	228
rs:WP_044599963	DNA topoisomerase III [Cronobacter sakazakii].	28.26	559	370	15	7	548	4	548	5e-62	228
rs:WP_031816622	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	5e-62	228
rs:WP_012933280	DNA topoisomerase III [Conexibacter woesei].	29.58	568	360	17	5	548	4	555	6e-62	229
rs:WP_017890391	hypothetical protein [Candidatus Caldatribacteirum californiense].	32.09	561	328	19	7	550	6	530	6e-62	229
rs:WP_014565111	DNA topoisomerase [Lactobacillus delbrueckii].	30.71	622	382	19	5	603	3	598	6e-62	229
rs:WP_000197436	DNA topoisomerase III [Vibrio cholerae].	28.60	563	349	15	8	539	6	546	6e-62	228
rs:WP_025521521	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	6e-62	228
rs:WP_025789721	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	6e-62	228
rs:WP_027852468	DNA topoisomerase III [Marinobacterium litorale].	30.35	547	352	16	8	539	5	537	6e-62	228
rs:WP_031849232	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	6e-62	228
rs:WP_039127867	DNA topoisomerase III, partial [Gilliamella apicola].	29.60	571	365	16	3	549	6	563	6e-62	227
rs:WP_008679336	DNA topoisomerase III [Clostridium sp. 7_2_43FAA].	30.14	574	353	16	7	559	6	552	6e-62	229
gpu:CP011832_1584	DNA topoisomerase 3 [Geobacillus sp. 12AMOR1]	31.89	555	313	22	7	546	5	509	6e-62	229
rs:WP_025802043	DNA topoisomerase III [Hafnia alvei].	29.12	546	350	15	7	531	4	533	6e-62	228
rs:WP_014544395	DNA topoisomerase III [Erwinia sp. Ejp617].	29.17	545	351	13	7	531	4	533	6e-62	228
tr:F0HU31_LACDL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.40	570	352	15	5	555	3	552	6e-62	226
rs:WP_019851501	DNA topoisomerase III [Desulfitobacterium sp. PCE1].	29.31	563	351	15	7	550	6	540	6e-62	229
rs:WP_025627208	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	6e-62	228
rs:WP_025500282	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	6e-62	228
rs:WP_038646639	DNA topoisomerase III [Pantoea rwandensis].	29.98	547	344	16	7	531	4	533	6e-62	228
rs:WP_025541060	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	6e-62	228
tr:A9MFG7_SALAR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.32	558	371	14	7	548	4	548	6e-62	228
rs:WP_040043199	DNA topoisomerase III [Pectobacterium carotovorum].	28.44	545	355	13	7	531	4	533	6e-62	228
rs:WP_032277657	DNA topoisomerase III, partial [Escherichia coli].	29.28	526	345	13	43	552	8	522	6e-62	227
rs:WP_001688676	DNA topoisomerase III [Escherichia coli].	28.65	562	372	14	7	552	4	552	6e-62	228
rs:WP_029831738	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	6e-62	228
rs:WP_032479936	DNA topoisomerase III [Vibrio cholerae].	28.57	567	344	15	8	539	6	546	6e-62	228
rs:WP_045832167	DNA topoisomerase III [Pantoea sp. BL1].	29.58	568	359	17	7	552	4	552	7e-62	228
rs:WP_032969960	DNA topoisomerase III [Cronobacter malonaticus].	28.26	559	370	15	7	548	4	548	7e-62	228
rs:WP_021167107	DNA topoisomerase 3 [Sporomusa ovata].	30.98	581	350	18	1	559	1	552	7e-62	229
rs:WP_032473562	DNA topoisomerase III [Vibrio cholerae].	28.57	567	344	15	8	539	6	546	7e-62	228
rs:WP_025633667	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	7e-62	228
rs:WP_025627575	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	7e-62	228
rs:WP_024702582	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	7e-62	228
rs:WP_038114435	DNA topoisomerase [Veillonella sp. AS16].	28.28	633	398	17	7	598	4	621	7e-62	229
rs:WP_008303213	DNA topoisomerase III [Glaciecola agarilytica].	29.67	546	345	13	8	530	5	534	7e-62	228
rs:WP_021453258	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	7e-62	228
rs:WP_041413492	DNA topoisomerase III, partial [Shewanella frigidimarina].	29.42	571	361	14	8	548	5	563	7e-62	228
rs:WP_045044901	DNA topoisomerase III [Photobacterium kishitanii].	30.54	560	354	16	8	548	6	549	7e-62	228
rs:WP_043046559	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.35	569	359	16	8	548	6	559	7e-62	228
rs:WP_021015936	DNA topoisomerase III [Serratia sp. ATCC 39006].	28.65	562	364	15	7	548	4	548	7e-62	228
rs:WP_025628854	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	564	363	15	7	548	5	553	7e-62	228
rs:WP_000197434	DNA topoisomerase III [Vibrio cholerae].	28.75	567	343	16	8	539	6	546	7e-62	228
rs:WP_004394830	DNA topoisomerase III [Vibrio metschnikovii].	27.74	620	407	17	8	604	6	607	7e-62	228
tr:Q084R2_SHEFN	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.42	571	361	14	8	548	5	563	7e-62	228
rs:WP_029796813	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	7e-62	228
rs:WP_009698532	DNA topoisomerase III [Vibrio sp. HENC-01].	29.43	564	361	15	7	548	5	553	7e-62	228
rs:WP_025442128	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	7e-62	228
rs:WP_041335167	DNA topoisomerase III [Marinobacter salarius].	28.97	542	358	11	8	530	5	538	7e-62	229
rs:WP_045042815	DNA topoisomerase III [Photobacterium kishitanii].	30.54	560	354	16	8	548	6	549	7e-62	228
rs:WP_029808658	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	7e-62	228
rs:WP_005461760	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	7e-62	228
tr:W1W322_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.16	632	399	17	7	598	4	620	7e-62	229
rs:WP_045629174	DNA topoisomerase III [Vibrio vulnificus].	29.42	571	352	15	7	548	5	553	7e-62	228
rs:WP_038872642	DNA topoisomerase III [Cronobacter dublinensis].	28.62	559	368	15	7	548	4	548	7e-62	228
rs:WP_034440480	DNA topoisomerase III [Candidatus Clostridium anorexicamassiliense].	30.23	612	361	20	7	590	6	579	8e-62	229
rs:WP_025793072	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	8e-62	228
rs:WP_025532715	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	8e-62	228
rs:WP_007985230	DNA topoisomerase III [Glaciecola chathamensis].	29.67	546	345	13	8	530	5	534	8e-62	227
rs:WP_025516126	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	8e-62	228
rs:WP_046618303	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	8e-62	227
rs:WP_025508783	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	8e-62	228
rs:WP_031622230	DNA topoisomerase III, partial [Salmonella enterica].	29.28	526	345	13	43	552	23	537	8e-62	227
rs:WP_045623503	DNA topoisomerase III [Vibrio vulnificus].	29.25	571	353	15	7	548	5	553	8e-62	228
rs:WP_039334584	DNA topoisomerase III [Pantoea rodasii].	30.16	547	343	15	7	531	4	533	8e-62	227
rs:WP_036956485	DNA topoisomerase III [Providencia alcalifaciens].	29.94	541	348	14	8	530	5	532	8e-62	227
rs:WP_022650874	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	28.30	576	381	14	7	563	4	566	8e-62	227
tr:A0A0C5VKB9_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.12	546	350	15	7	531	4	533	8e-62	227
rs:WP_009843452	DNA topoisomerase III [Vibrio sp. AND4].	29.91	565	357	16	7	548	5	553	8e-62	228
rs:WP_038888133	DNA topoisomerase III [Cronobacter dublinensis].	28.88	561	364	16	7	548	4	548	8e-62	227
rs:WP_011878189	DNA topoisomerase III [Desulfotomaculum reducens].	31.90	583	339	24	7	563	5	555	8e-62	228
rs:WP_045619965	DNA topoisomerase III [Vibrio vulnificus].	29.25	571	353	15	7	548	5	553	8e-62	228
rs:WP_029842486	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	9e-62	228
rs:WP_029802080	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	9e-62	228
rs:WP_022633477	DNA topoisomerase III [Dickeya solani].	28.47	562	365	14	7	548	4	548	9e-62	227
rs:WP_009668885	DNA topoisomerase III [gamma proteobacterium IMCC1989].	28.52	596	363	15	8	553	5	587	9e-62	228
rs:WP_018305366	DNA topoisomerase III [Desulfitobacterium hafniense].	28.78	608	381	17	7	593	6	582	9e-62	229
rs:WP_008110346	DNA topoisomerase III [Pantoea sp. YR343].	29.58	568	359	16	7	552	4	552	9e-62	227
rs:WP_023898920	MULTISPECIES: DNA topoisomerase III [Cronobacter].	28.26	559	370	15	7	548	4	548	9e-62	227
tr:K1JUJ7_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.51	567	336	14	7	530	4	555	9e-62	228
rs:WP_011080930	DNA topoisomerase III [Vibrio vulnificus].	29.42	571	352	15	7	548	5	553	9e-62	228
rs:WP_044023984	DNA topoisomerase III [Vibrio vulnificus].	29.42	571	352	15	7	548	5	553	9e-62	228
rs:WP_017797775	DNA topoisomerase III [Oceanobacillus kimchii].	31.64	550	336	17	3	539	2	524	9e-62	228
rs:WP_000197431	DNA topoisomerase III [Vibrio cholerae].	28.57	567	344	15	8	539	6	546	9e-62	227
tr:A0A0A3FDX4_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.43	564	361	15	7	548	5	553	9e-62	227
rs:WP_012128555	DNA topoisomerase III [Vibrio campbellii].	29.43	564	361	15	7	548	5	553	9e-62	227
rs:WP_029851232	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	564	363	15	7	548	5	553	1e-61	227
rs:WP_031778422	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	1e-61	227
rs:WP_006174820	DNA topoisomerase III [Enterobacter cancerogenus].	28.12	576	382	14	7	563	4	566	1e-61	227
rs:WP_042780750	DNA topoisomerase III [Vibrio parahaemolyticus].	28.95	563	365	14	7	548	5	553	1e-61	227
rs:WP_017032445	DNA topoisomerase III [Vibrio breoganii].	29.54	589	363	18	7	564	5	572	1e-61	227
rs:WP_034022901	DNA topoisomerase [Pseudomonas aeruginosa].	30.02	573	341	17	8	532	5	565	1e-61	228
rs:WP_029839225	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	1e-61	227
rs:WP_005485385	DNA topoisomerase III [Vibrio parahaemolyticus].	29.43	564	361	15	7	548	5	553	1e-61	227
rs:WP_011573665	DNA topoisomerase III [Pseudoalteromonas atlantica].	29.78	554	342	13	8	530	5	542	1e-61	227
rs:WP_045035773	DNA topoisomerase III [Photobacterium iliopiscarium].	30.71	560	353	17	8	548	6	549	1e-61	227
rs:WP_014069859	DNA topoisomerase III [Enterobacter asburiae].	28.65	576	379	15	7	563	4	566	1e-61	227
tr:A0A034TL34_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.96	564	360	15	7	548	5	555	1e-61	227
rs:WP_006691043	DNA topoisomerase [Selenomonas flueggei].	29.48	553	342	15	8	531	5	538	1e-61	228
rs:WP_045069951	DNA topoisomerase III [Photobacterium leiognathi].	30.05	559	360	14	8	548	6	551	1e-61	227
rs:WP_011093894	DNA topoisomerase III [Pectobacterium atrosepticum].	28.44	545	355	13	7	531	4	533	1e-61	227
rs:WP_047369938	DNA topoisomerase III [Kluyvera intermedia].	29.43	564	357	17	7	548	4	548	1e-61	227
rs:WP_039045709	DNA topoisomerase III, partial [Plesiomonas shigelloides].	29.04	544	353	16	8	531	5	535	1e-61	227
rs:WP_002053203	DNA topoisomerase III [Vibrio cholerae].	28.57	567	344	15	8	539	6	546	1e-61	227
rs:WP_038891461	DNA topoisomerase III [Vibrio campbellii].	29.43	564	361	15	7	548	5	553	1e-61	227
rs:WP_046019227	DNA topoisomerase III [Marinomonas sp. S3726].	29.15	542	354	14	8	531	5	534	1e-61	227
rs:WP_024968239	DNA topoisomerase III [Pantoea sp. IMH].	28.83	562	363	14	7	548	4	548	1e-61	227
rs:WP_034882663	DNA topoisomerase III, partial [Gilliamella apicola].	28.62	573	369	14	3	549	6	564	1e-61	226
rs:WP_029810451	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	1e-61	227
rs:WP_023324481	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	28.30	576	381	14	7	563	4	566	1e-61	227
rs:WP_028974183	hypothetical protein [Spirochaeta cellobiosiphila].	29.36	613	374	25	1	591	1	576	1e-61	228
rs:WP_029799342	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.19	555	358	14	8	540	6	547	1e-61	225
rs:WP_007760307	DNA topoisomerase III [Cronobacter turicensis].	28.26	559	370	15	7	548	4	548	1e-61	227
rs:WP_000197432	DNA topoisomerase III [Vibrio cholerae].	28.92	567	342	16	8	539	6	546	1e-61	227
rs:WP_036979414	DNA topoisomerase III [Providencia alcalifaciens].	29.76	541	349	14	8	530	5	532	1e-61	227
rs:WP_015465256	DNA topoisomerase III [Psychromonas sp. CNPT3].	29.06	561	371	11	8	553	5	553	1e-61	227
rs:WP_029850627	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.19	555	358	14	8	540	6	547	1e-61	225
rs:WP_010681314	DNA topoisomerase [Acetivibrio cellulolyticus].	30.22	589	363	18	8	557	7	586	1e-61	227
rs:WP_025552790	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	1e-61	227
rs:WP_047051503	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	1e-61	227
rs:WP_002433736	DNA topoisomerase III [Escherichia hermannii].	28.52	561	364	14	8	548	5	548	1e-61	227
rs:WP_045625682	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	1e-61	227
rs:WP_015297075	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	1e-61	227
gp:CP002469_2073	DNA topoisomerase III [Vibrio vulnificus MO6-24/O]	29.42	571	352	15	7	548	14	562	1e-61	227
rs:WP_000197427	DNA topoisomerase III [Vibrio cholerae].	28.24	563	351	14	8	539	6	546	1e-61	227
rs:WP_046356583	DNA topoisomerase III [Pseudoalteromonas luteoviolacea].	29.07	571	359	15	8	553	5	554	1e-61	227
rs:WP_043865227	DNA topoisomerase III [Enterobacter aerogenes].	28.52	561	364	14	8	548	5	548	1e-61	227
rs:WP_025541336	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	1e-61	227
rs:WP_038968960	DNA topoisomerase III [Vibrio vulnificus].	29.55	572	350	16	7	548	5	553	1e-61	227
rs:WP_012864143	DNA topoisomerase III [Veillonella parvula].	28.32	632	396	18	8	598	5	620	1e-61	229
rs:WP_045325423	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.31	563	361	15	8	548	6	553	1e-61	226
rs:WP_042859776	DNA topoisomerase III [Dickeya sp. NCPPB 3274].	28.27	566	369	14	7	552	4	552	1e-61	227
rs:WP_040000899	DNA topoisomerase III [Dickeya chrysanthemi].	28.29	562	374	13	7	552	4	552	1e-61	227
rs:WP_015730446	DNA topoisomerase III [Pectobacterium wasabiae].	28.62	545	354	13	7	531	4	533	1e-61	227
rs:WP_036171005	DNA topoisomerase III [Lysinibacillus massiliensis].	29.58	578	356	18	5	559	4	553	1e-61	228
rs:WP_023299889	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	28.30	576	381	14	7	563	4	566	1e-61	227
rs:WP_039549510	DNA topoisomerase III [Pectobacterium carotovorum].	28.44	545	355	13	7	531	4	533	1e-61	227
rs:WP_023296331	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	1e-61	227
rs:WP_027712141	DNA topoisomerase III [Dickeya chrysanthemi].	28.29	562	374	13	7	552	4	552	1e-61	227
rs:WP_039384680	DNA topoisomerase III [Pantoea sp. PSNIH1].	29.08	564	359	16	7	548	4	548	1e-61	227
rs:WP_025638623	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	1e-61	227
rs:WP_045421631	DNA topoisomerase III [Vibrio campbellii].	29.43	564	361	15	7	548	5	553	1e-61	227
rs:WP_045594548	DNA topoisomerase III [Vibrio vulnificus].	29.55	572	350	16	7	548	5	553	1e-61	227
rs:WP_039450498	DNA topoisomerase III [Vibrio vulnificus].	29.42	571	352	15	7	548	5	553	1e-61	227
rs:WP_012769917	MULTISPECIES: DNA topoisomerase III [Dickeya].	28.29	562	374	13	7	552	4	552	1e-61	227
rs:WP_013752942	DNA topoisomerase III [Glaciecola sp. 4H-3-7+YE-5].	29.67	546	345	13	8	530	5	534	1e-61	226
rs:WP_033014155	DNA topoisomerase III [Geobacillus stearothermophilus].	31.89	555	313	22	7	546	5	509	1e-61	228
rs:WP_045453629	DNA topoisomerase III [Vibrio campbellii].	29.43	564	361	15	7	548	5	553	1e-61	227
rs:WP_017053489	DNA topoisomerase III [Vibrio genomosp. F6].	29.47	570	353	15	7	548	5	553	1e-61	227
rs:WP_045331141	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	1e-61	226
rs:WP_014699893	MULTISPECIES: DNA topoisomerase III [Pectobacterium].	28.62	545	354	13	7	531	4	533	1e-61	226
rs:WP_038154391	DNA topoisomerase III [Trabulsiella guamensis].	28.62	580	374	16	7	563	4	566	1e-61	227
rs:WP_025623522	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	1e-61	227
rs:WP_038224744	DNA topoisomerase III [Xenorhabdus bovienii].	29.10	543	354	14	7	531	4	533	1e-61	226
rs:WP_001235882	DNA topoisomerase III [Salmonella enterica].	28.47	576	368	17	7	552	4	565	2e-61	227
rs:WP_045333361	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	2e-61	226
rs:WP_039986868	DNA topoisomerase III [Vibrio owensii].	29.43	564	361	15	7	548	5	553	2e-61	227
rs:WP_039989635	DNA topoisomerase III, partial [Glaciecola arctica].	28.82	569	364	15	7	548	4	558	2e-61	226
rs:WP_045595832	DNA topoisomerase III [Vibrio vulnificus].	29.42	571	352	15	7	548	5	553	2e-61	227
rs:WP_017384681	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	28.30	576	381	14	7	563	4	566	2e-61	226
rs:WP_013202431	DNA topoisomerase III [Erwinia billingiae].	28.81	545	353	13	7	531	4	533	2e-61	226
rs:WP_024061224	DNA topoisomerase [Veillonella dispar].	27.65	633	401	17	7	598	4	620	2e-61	229
rs:WP_046596356	DNA topoisomerase III [Salmonella enterica].	28.29	562	374	14	7	552	4	552	2e-61	226
rs:WP_004157807	DNA topoisomerase III [Erwinia amylovora].	29.17	545	351	13	7	531	4	533	2e-61	226
rs:WP_006962977	DNA topoisomerase III [Vibrio coralliilyticus].	28.72	564	365	15	7	548	5	553	2e-61	227
rs:WP_009089894	DNA topoisomerase III [Pantoea sp. Sc1].	27.94	562	368	14	7	548	4	548	2e-61	226
rs:WP_033929799	DNA topoisomerase III [Vibrio cholerae].	28.75	567	343	16	8	539	6	546	2e-61	226
tr:A0A080KI01_9GAMM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.62	573	369	14	3	549	6	564	2e-61	226
rs:WP_029857514	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	2e-61	227
rs:WP_024559605	DNA topoisomerase III [Cronobacter pulveris].	28.03	578	380	15	7	563	4	566	2e-61	226
rs:WP_028255426	DNA topoisomerase [Veillonella magna].	28.40	588	367	14	7	553	4	578	2e-61	229
rs:WP_045347463	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	2e-61	226
rs:WP_009351396	DNA topoisomerase [Veillonella sp. oral taxon 158].	27.96	633	399	18	7	598	4	620	2e-61	228
rs:WP_045338463	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	2e-61	226
rs:WP_039295725	DNA topoisomerase III [Pectobacterium atrosepticum].	28.44	545	355	13	7	531	4	533	2e-61	226
rs:WP_039467859	DNA topoisomerase III [Vibrio vulnificus].	29.55	572	350	16	7	548	5	553	2e-61	227
rs:WP_032673185	DNA topoisomerase III [Enterobacter sp. BIDMC 27].	28.30	576	381	14	7	563	4	566	2e-61	226
rs:WP_020959817	DNA topoisomerase III [Geobacillus sp. JF8].	31.56	564	314	22	7	548	5	518	2e-61	227
rs:WP_011146773	DNA topoisomerase III [Photorhabdus luminescens].	28.75	546	350	14	8	531	5	533	2e-61	226
rs:WP_045148393	DNA topoisomerase III [Photobacterium angustum].	30.59	559	357	14	8	548	6	551	2e-61	227
rs:WP_045612368	DNA topoisomerase III [Vibrio vulnificus].	29.42	571	352	15	7	548	5	553	2e-61	226
rs:WP_032619841	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	28.65	576	379	15	7	563	4	566	2e-61	226
rs:WP_013358056	DNA topoisomerase III [Pantoea vagans].	28.09	566	370	14	7	552	4	552	2e-61	226
rs:WP_008987582	DNA topoisomerase III [Photobacterium leiognathi].	30.30	561	356	16	8	548	6	551	2e-61	227
rs:WP_025570202	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	2e-61	226
rs:WP_017243165	DNA topoisomerase III [Vibrio breoganii].	29.54	589	363	18	7	564	5	572	2e-61	226
rs:WP_019276521	DNA topoisomerase III [Vibrio coralliilyticus].	28.72	564	365	15	7	548	5	553	2e-61	226
rs:WP_041851653	DNA topoisomerase III [Enterobacter sp. Bisph2].	29.43	564	357	17	7	548	4	548	2e-61	226
rs:WP_025526041	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	2e-61	226
rs:WP_037353282	DNA topoisomerase [Selenomonas sp. FC4001].	30.45	555	338	15	8	531	5	542	2e-61	229
rs:WP_017027834	DNA topoisomerase III [Vibrio breoganii].	29.39	592	363	18	7	564	5	575	2e-61	226
rs:WP_020001908	hypothetical protein [Desulfovibrio desulfuricans].	29.38	599	389	19	7	597	4	576	2e-61	227
rs:WP_039487073	DNA topoisomerase III [Pectobacterium carotovorum].	28.44	545	355	13	7	531	4	533	2e-61	226
rs:WP_034887878	DNA topoisomerase III [Erwinia typographi].	28.70	547	351	14	7	531	4	533	2e-61	226
rs:WP_027477969	DNA topoisomerase III [Curvibacter gracilis].	28.28	548	365	12	7	539	4	538	2e-61	228
rs:WP_008713605	DNA topoisomerase III [Veillonella sp. 3_1_44].	27.65	633	401	17	7	598	4	620	2e-61	228
rs:WP_033783268	DNA topoisomerase III [Pantoea sp. 9140].	28.09	566	370	14	7	552	4	552	2e-61	226
rs:WP_047061605	DNA topoisomerase III [Enterobacter asburiae].	28.30	576	381	14	7	563	4	566	2e-61	226
rs:WP_021704335	DNA topoisomerase III [Vibrio proteolyticus].	29.75	558	333	17	7	530	5	537	2e-61	226
rs:WP_022940269	DNA topoisomerase III [Psychromonas hadalis].	30.97	536	348	11	8	531	5	530	2e-61	226
rs:WP_015740971	DNA topoisomerase III [Cronobacter turicensis].	28.26	559	370	15	7	548	4	548	2e-61	226
rs:WP_025508845	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	564	363	15	7	548	5	553	2e-61	226
rs:WP_028017189	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	2e-61	226
rs:WP_035165068	topoisomerase I [Lactobacillus delbrueckii].	30.71	622	382	19	5	603	3	598	2e-61	227
rs:WP_045346457	DNA topoisomerase III [Enterobacter cloacae].	28.12	576	382	14	7	563	4	566	2e-61	226
rs:WP_032482725	DNA topoisomerase III [Vibrio cholerae].	28.06	563	352	15	8	539	6	546	2e-61	226
rs:WP_014257080	DNA topoisomerase [[Clostridium] clariflavum].	30.10	588	365	15	8	557	7	586	2e-61	226
rs:WP_043084421	DNA topoisomerase III [Pluralibacter gergoviae].	28.67	558	369	14	7	548	4	548	2e-61	226
rs:WP_045184773	DNA topoisomerase III [Photobacterium angustum].	31.00	542	345	13	8	531	6	536	2e-61	226
rs:WP_017799846	DNA topoisomerase III [Erwinia toletana].	29.67	546	347	15	7	531	4	533	2e-61	226
rs:WP_033918639	hypothetical protein [Enterococcus faecalis].	30.97	565	336	19	7	544	5	542	2e-61	228
rs:WP_000197441	DNA topoisomerase III [Vibrio cholerae].	28.57	567	344	15	8	539	6	546	2e-61	226
rs:WP_023100649	hypothetical protein [Pseudomonas aeruginosa].	29.84	573	342	16	8	532	5	565	2e-61	227
rs:WP_032471176	DNA topoisomerase III [Vibrio cholerae].	28.42	563	350	15	8	539	6	546	2e-61	226
rs:WP_039540432	DNA topoisomerase III [Vibrio vulnificus].	29.55	572	350	16	7	548	5	553	2e-61	226
tr:K6Z8H7_9ALTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.82	569	364	15	7	548	4	558	2e-61	226
rs:WP_012277719	DNA topoisomerase III [Shewanella halifaxensis].	30.46	581	342	18	8	548	5	563	2e-61	227
rs:WP_044039668	DNA topoisomerase III [Clostridium sp. M2/40].	30.27	555	345	17	7	548	5	530	2e-61	228
rs:WP_038901156	DNA topoisomerase III [Dickeya dadantii].	28.47	562	365	14	7	548	4	548	2e-61	226
rs:WP_035131896	DNA topoisomerase III [Clostridium sulfidigenes].	29.76	578	350	19	7	559	6	552	2e-61	228
rs:WP_005494459	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	2e-61	226
rs:WP_001235849	DNA topoisomerase III [Escherichia albertii].	28.34	561	373	14	8	552	5	552	2e-61	226
tr:A0A0A5S663_KLEOX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.83	562	371	13	7	552	4	552	2e-61	226
rs:WP_038254850	DNA topoisomerase III [Xenorhabdus bovienii].	29.10	543	354	14	7	531	4	533	2e-61	226
rs:WP_036084712	DNA topoisomerase III [Listeria booriae].	30.39	533	335	12	7	532	6	509	3e-61	227
rs:WP_025526834	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	3e-61	226
rs:WP_016396426	DNA topoisomerase III family protein [Lactobacillus delbrueckii].	30.71	622	382	19	5	603	3	598	3e-61	227
rs:WP_007477853	DNA topoisomerase III [Listeria fleischmannii].	28.21	599	384	17	5	590	4	569	3e-61	227
rs:WP_036100249	DNA topoisomerase III [Listeria riparia].	30.39	533	335	12	7	532	6	509	3e-61	227
rs:WP_026766366	DNA topoisomerase [Selenomonas ruminantium].	30.38	553	341	14	8	531	5	542	3e-61	229
rs:WP_045588988	DNA topoisomerase III [Vibrio vulnificus].	29.72	572	349	16	7	548	5	553	3e-61	226
rs:WP_036975663	DNA topoisomerase III [Providencia alcalifaciens].	29.70	542	350	14	7	530	4	532	3e-61	226
rs:WP_037440394	DNA topoisomerase III, partial [Shewanella sp. YQH10].	29.14	573	362	15	8	552	5	561	3e-61	226
rs:WP_026130810	DNA topoisomerase III [Vibrio vulnificus].	29.25	571	353	15	7	548	5	553	3e-61	226
gpu:CP010423_2107	DNA topoisomerase III [Pragia fontium]	30.04	546	343	15	8	531	5	533	3e-61	226
rs:WP_034759989	DNA topoisomerase III [Bacillus vietnamensis].	30.24	615	380	21	7	603	6	589	3e-61	227
rs:WP_006990687	DNA topoisomerase III [Glaciecola mesophila].	29.08	564	359	14	8	548	5	550	3e-61	226
rs:WP_044503985	DNA topoisomerase [Megasphaera sp. NP3].	29.33	566	363	13	7	552	4	552	3e-61	227
rs:WP_013843762	DNA topoisomerase III [Desulfotomaculum ruminis].	31.93	595	334	21	5	563	4	563	3e-61	227
rs:WP_032477814	DNA topoisomerase III [Vibrio cholerae].	28.42	563	350	15	8	539	6	546	3e-61	226
rs:WP_010449456	DNA topoisomerase III [Vibrio rotiferianus].	29.43	564	361	16	7	548	5	553	3e-61	226
rs:WP_007105160	DNA topoisomerase III [Glaciecola polaris].	29.29	560	365	13	8	548	5	552	3e-61	226
rs:WP_042988236	DNA topoisomerase III [Vibrio cholerae].	28.40	567	345	15	8	539	6	546	3e-61	226
rs:WP_036963785	DNA topoisomerase III [Providencia alcalifaciens].	29.70	542	350	14	7	530	4	532	3e-61	226
rs:WP_036965804	DNA topoisomerase III [Providencia alcalifaciens].	29.70	542	350	14	7	530	4	532	3e-61	226
rs:WP_025503057	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	3e-61	226
rs:WP_023118088	hypothetical protein [Pseudomonas aeruginosa].	29.67	573	343	16	8	532	5	565	3e-61	227
rs:WP_028401311	DNA topoisomerase III [Bacillus panaciterrae].	30.21	566	346	17	3	548	2	538	3e-61	227
rs:WP_045336155	DNA topoisomerase III [Enterobacter asburiae].	28.47	576	380	14	7	563	4	566	3e-61	226
rs:WP_002044380	DNA topoisomerase III [Vibrio cholerae].	28.40	567	345	15	8	539	6	546	3e-61	226
rs:WP_000197433	DNA topoisomerase III [Vibrio cholerae].	26.90	632	399	17	8	603	6	610	3e-61	226
rs:WP_044102072	DNA topoisomerase III, partial [Xanthomonas citri].	34.06	414	248	10	4	408	1	398	3e-61	219
rs:WP_011149881	DNA topoisomerase III [Vibrio vulnificus].	29.25	571	353	15	7	548	5	553	3e-61	226
rs:WP_031415725	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	564	363	15	7	548	5	553	3e-61	226
rs:WP_029805727	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	3e-61	226
tr:I3V5K3_PSEPU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.67	573	343	16	8	532	5	565	3e-61	227
rs:WP_031828274	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	3e-61	226
rs:WP_047062623	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	4e-61	226
rs:WP_006233033	DNA topoisomerase III [Photobacterium profundum].	28.64	625	399	16	8	603	6	612	4e-61	226
rs:WP_009660877	DNA topoisomerase III [Veillonella sp. ACP1].	27.93	641	389	19	7	598	4	620	4e-61	228
rs:WP_047109038	DNA topoisomerase III [Vibrio vulnificus].	29.42	571	352	15	7	548	5	553	4e-61	226
rs:WP_005514989	DNA topoisomerase III [Vibrio mimicus].	28.14	565	349	14	8	539	6	546	4e-61	226
rs:WP_006658753	DNA topoisomerase III [Providencia alcalifaciens].	29.70	542	350	14	7	530	4	532	4e-61	226
rs:WP_037353159	DNA topoisomerase III, partial [Salinivibrio socompensis].	29.04	551	357	14	7	536	5	542	4e-61	226
rs:WP_026050788	DNA topoisomerase III [Vibrio vulnificus].	29.42	571	352	15	7	548	5	553	4e-61	226
rs:WP_029838760	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.52	542	347	14	8	527	6	534	4e-61	223
rs:WP_001959922	DNA topoisomerase III [Vibrio cholerae].	28.40	567	345	15	8	539	6	546	4e-61	226
rs:WP_038188930	DNA topoisomerase III [Xenorhabdus bovienii].	28.91	543	355	14	7	531	4	533	4e-61	226
rs:WP_031515700	DNA topoisomerase III [Desulfotomaculum alkaliphilum].	31.50	565	336	20	5	548	4	538	4e-61	227
rs:WP_033928704	DNA topoisomerase III [Vibrio cholerae].	28.40	567	345	15	8	539	6	546	4e-61	226
rs:WP_036770428	DNA topoisomerase III, partial [Plesiomonas shigelloides].	29.04	544	353	16	8	531	5	535	4e-61	226
rs:WP_006119409	DNA topoisomerase III [Pantoea stewartii].	28.28	541	361	12	7	531	4	533	4e-61	225
rs:WP_036023794	DNA topoisomerase III [Leminorella grimontii].	29.10	567	355	17	7	548	4	548	4e-61	226
rs:WP_004892848	DNA topoisomerase III [Klebsiella pneumoniae].	28.83	562	363	14	7	548	4	548	4e-61	226
rs:WP_038208626	DNA topoisomerase III [Xenorhabdus bovienii].	29.10	543	354	14	7	531	4	533	4e-61	225
rs:WP_039537398	DNA topoisomerase III [Pectobacterium carotovorum].	28.26	545	356	13	7	531	4	533	4e-61	225
rs:WP_040988788	DNA topoisomerase III [Vibrio sp. DCR 1-4-2].	30.11	568	352	18	7	548	5	553	4e-61	225
rs:WP_019542902	hypothetical protein [Selenomonas bovis].	29.71	579	368	15	7	559	5	570	4e-61	226
rs:WP_009490444	DNA topoisomerase III [Catellicoccus marimammalium].	31.06	573	355	17	5	557	3	555	4e-61	227
rs:WP_005532611	DNA topoisomerase III [Vibrio campbellii].	29.43	564	361	15	7	548	5	553	4e-61	226
tr:W1GKG1_ECOLX	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.09	526	346	13	43	552	2	516	4e-61	224
rs:WP_000197438	DNA topoisomerase III [Vibrio cholerae].	28.42	563	350	15	8	539	6	546	4e-61	225
rs:WP_039505489	DNA topoisomerase III [Pectobacterium carotovorum].	28.44	545	355	13	7	531	4	533	4e-61	225
rs:WP_007678182	DNA topoisomerase III [Cronobacter condimenti].	28.80	559	367	15	7	548	4	548	5e-61	225
rs:WP_024893846	DNA topoisomerase III [Acidithiobacillus thiooxidans].	30.00	570	353	14	7	548	4	555	5e-61	226
rs:WP_029592603	DNA topoisomerase III [Cronobacter pulveris].	27.85	578	381	15	7	563	4	566	5e-61	225
rs:WP_047174037	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	5e-61	225
sp:TOP3_VIBCH	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	28.24	563	351	15	8	539	6	546	5e-61	225
rs:WP_045288446	DNA topoisomerase III [Pluralibacter gergoviae].	28.67	558	369	14	7	548	4	548	5e-61	225
rs:WP_019376018	DNA topoisomerase III [Virgibacillus halodenitrificans].	30.74	553	337	16	3	538	2	525	5e-61	226
rs:WP_033955320	DNA topoisomerase [Pseudomonas aeruginosa].	29.67	573	343	16	8	532	5	565	5e-61	226
rs:WP_038863407	DNA topoisomerase III [Cronobacter muytjensii].	28.34	561	367	16	7	548	4	548	5e-61	225
rs:WP_029842060	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	564	363	15	7	548	5	553	5e-61	225
rs:WP_004121401	MULTISPECIES: DNA topoisomerase III [Klebsiella].	28.65	562	372	13	7	552	4	552	5e-61	225
rs:WP_046075295	DNA topoisomerase III [Salinivibrio sp. KP-1].	29.43	564	356	15	7	548	5	548	5e-61	226
rs:WP_045369398	DNA topoisomerase III [Vibrio campbellii].	29.26	564	362	15	7	548	5	553	5e-61	225
rs:WP_032119053	DNA topoisomerase III [Clostridium sp. CL-2].	29.71	579	359	18	1	559	1	551	5e-61	226
rs:WP_040073611	DNA topoisomerase III [Vibrio cholerae].	28.24	563	351	15	8	539	6	546	5e-61	225
rs:WP_033025373	DNA topoisomerase III [Geobacillus sp. CAMR5420].	31.42	557	313	22	7	546	5	509	5e-61	226
rs:WP_000197439	DNA topoisomerase III [Vibrio cholerae].	28.24	563	351	15	8	539	6	546	5e-61	225
rs:WP_000197426	DNA topoisomerase III [Vibrio cholerae].	28.57	567	344	16	8	539	6	546	5e-61	225
rs:WP_011219248	DNA topoisomerase III [Photobacterium profundum].	28.16	625	402	15	8	603	6	612	5e-61	225
rs:WP_038884305	DNA topoisomerase III [Vibrio rotiferianus].	29.26	564	362	15	7	548	5	553	5e-61	225
rs:WP_035116511	DNA topoisomerase III [Clostridium sp. NCR].	30.64	607	329	22	5	580	4	549	5e-61	226
rs:WP_034790651	DNA topoisomerase III [Ewingella americana].	29.49	546	346	15	8	531	5	533	6e-61	225
rs:WP_035147711	DNA topoisomerase III [Clostridium tetanomorphum].	30.46	568	346	18	1	548	1	539	6e-61	226
rs:WP_000197440	DNA topoisomerase III [Vibrio cholerae].	28.57	567	344	15	8	539	6	546	6e-61	225
rs:WP_042267858	DNA topoisomerase III [Clostridium perfringens].	31.20	577	342	18	7	559	8	553	6e-61	226
rs:WP_013317851	DNA topoisomerase III [Dickeya dadantii].	28.47	562	365	14	7	548	4	548	6e-61	225
rs:WP_033931233	DNA topoisomerase III [Vibrio cholerae].	28.42	563	350	15	8	539	6	546	6e-61	225
rs:WP_044748403	DNA topoisomerase III [Bacillus alveayuensis].	29.62	557	359	15	4	544	1	540	6e-61	226
rs:WP_023335338	DNA topoisomerase III [Enterobacter sp. MGH 24].	28.12	576	382	14	7	563	4	566	6e-61	225
rs:WP_012325583	DNA topoisomerase III [Shewanella woodyi].	29.12	577	366	14	8	553	5	569	6e-61	225
rs:WP_038922734	DNA topoisomerase III [Dickeya dadantii].	28.47	562	365	14	7	548	4	548	6e-61	225
rs:WP_033082620	DNA topoisomerase III [Colwellia psychrerythraea].	30.74	579	354	18	8	555	5	567	6e-61	225
rs:WP_046029173	DNA topoisomerase III [Vibrio vulnificus].	29.55	572	350	16	7	548	5	553	6e-61	225
rs:WP_045377329	DNA topoisomerase III [Vibrio campbellii].	29.26	564	362	15	7	548	5	553	6e-61	225
rs:WP_039277542	DNA topoisomerase III [Pectobacterium carotovorum].	28.28	541	361	13	7	531	4	533	6e-61	225
rs:WP_042407884	DNA topoisomerase III [Geobacillus caldoxylosilyticus].	29.73	555	361	15	4	544	1	540	6e-61	226
rs:WP_031943421	conjugal transfer protein TraF [uncultured bacterium].	29.16	559	359	12	4	539	1	545	6e-61	225
rs:WP_029863194	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.19	555	358	14	8	540	6	547	6e-61	223
rs:WP_014424541	topoisomerase III [Selenomonas ruminantium].	29.24	578	368	14	7	559	6	567	6e-61	227
rs:WP_038938912	DNA topoisomerase III [Vibrio vulnificus].	29.42	571	352	15	7	548	5	553	6e-61	225
rs:WP_024558046	DNA topoisomerase III [Cronobacter pulveris].	27.85	578	381	15	7	563	4	566	7e-61	225
rs:WP_005498870	DNA topoisomerase III [Shewanella benthica].	27.88	617	397	16	8	593	5	604	7e-61	225
rs:WP_045151977	DNA topoisomerase III [Photobacterium angustum].	30.81	542	346	13	8	531	6	536	7e-61	225
tr:Q7VLX0_HAEDU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.18	574	389	14	4	559	2	564	7e-61	224
rs:WP_016808486	DNA topoisomerase III [Klebsiella oxytoca].	28.47	562	373	13	7	552	4	552	7e-61	225
rs:WP_046101928	DNA topoisomerase III [Pantoea anthophila].	27.94	562	368	14	7	548	4	548	7e-61	224
rs:WP_045127804	DNA topoisomerase III [Photobacterium angustum].	30.81	542	346	13	8	531	6	536	7e-61	225
rs:WP_045353661	DNA topoisomerase III [Enterobacter asburiae].	28.12	576	382	14	7	563	4	566	7e-61	224
rs:WP_033741875	DNA topoisomerase III [Pantoea stewartii].	28.47	541	360	12	7	531	4	533	7e-61	224
rs:WP_000197428	DNA topoisomerase III [Vibrio cholerae].	28.40	567	345	15	8	539	6	546	7e-61	225
rs:WP_032657921	DNA topoisomerase III [Enterobacter sp. DC1].	28.12	576	382	14	7	563	4	566	7e-61	224
rs:WP_029812642	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.52	542	347	14	8	527	6	534	7e-61	222
rs:WP_044127250	DNA topoisomerase III [Vibrio cholerae].	28.14	565	349	14	8	539	6	546	7e-61	225
rs:WP_033746697	DNA topoisomerase III [Pantoea sp. NGS-ED-1003].	28.11	562	367	14	7	548	4	548	8e-61	224
tr:A0A0C7KFB3_XANCE	SubName: Full=TopB protein {ECO:0000313|EMBL:CEO96463.1};	27.92	616	403	18	8	603	5	599	8e-61	226
tr:W7DUD1_9LIST	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.24	602	380	19	5	590	4	569	8e-61	225
rs:WP_006809125	MULTISPECIES: DNA topoisomerase III [Enterobacter].	28.12	576	382	14	7	563	4	566	8e-61	224
rs:WP_045608605	DNA topoisomerase III [Vibrio vulnificus].	29.25	571	353	15	7	548	5	553	8e-61	225
tr:F0BTR5_9XANT	SubName: Full=Topoisomerase IA {ECO:0000313|EMBL:EGD13677.1}; Flags: Fragment;	28.64	618	396	19	8	603	5	599	8e-61	225
rs:WP_031586293	DNA topoisomerase [Selenomonas bovis].	30.39	566	325	18	8	530	5	544	8e-61	227
rs:WP_038911181	DNA topoisomerase III [Dickeya dadantii].	28.29	562	366	14	7	548	4	548	8e-61	224
rs:WP_045083314	MULTISPECIES: DNA topoisomerase III [Photobacterium].	30.81	542	346	13	8	531	6	536	8e-61	225
rs:WP_002879284	DNA topoisomerase [Lactobacillus delbrueckii].	30.19	626	380	19	5	603	3	598	8e-61	226
rs:WP_019845046	DNA topoisomerase III [Dickeya zeae].	27.94	562	376	13	7	552	4	552	8e-61	224
rs:WP_038918989	DNA topoisomerase III [Dickeya sp. MK7].	28.27	566	369	14	7	552	4	552	8e-61	224
rs:WP_038914000	DNA topoisomerase III [Dickeya zeae].	27.94	562	376	13	7	552	4	552	8e-61	224
rs:WP_008600558	DNA topoisomerase III [Veillonella sp. 6_1_27].	27.80	633	400	18	7	598	4	620	8e-61	226
rs:WP_004693293	DNA topoisomerase [Veillonella parvula].	27.65	633	401	17	7	598	4	620	8e-61	226
rs:WP_009653400	DNA topoisomerase III [Klebsiella sp. OBRC7].	28.65	562	372	13	7	552	4	552	8e-61	224
rs:WP_041956145	DNA topoisomerase III [Vibrio parahaemolyticus].	29.26	564	362	15	7	548	5	553	8e-61	224
rs:WP_032414799	DNA topoisomerase III [Klebsiella pneumoniae].	28.83	562	363	14	7	548	4	548	9e-61	224
tr:R8ANU3_PLESH	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.04	544	353	16	8	531	5	535	9e-61	225
rs:WP_004620647	DNA topoisomerase III [[Clostridium] papyrosolvens].	28.08	609	387	14	3	585	2	585	9e-61	226
rs:WP_038192148	DNA topoisomerase III [Xenorhabdus bovienii].	28.91	543	355	14	7	531	4	533	9e-61	224
rs:WP_001235879	DNA topoisomerase III, partial [Salmonella enterica].	28.30	576	370	16	7	552	4	566	9e-61	224
rs:WP_041603685	DNA topoisomerase III [Haemophilus ducreyi].	27.18	574	389	14	4	559	1	563	9e-61	224
rs:WP_045338920	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	9e-61	224
rs:WP_033811278	DNA topoisomerase [Escherichia coli].	28.55	557	366	11	4	539	1	546	9e-61	225
rs:WP_032095057	MULTISPECIES: DNA topoisomerase III [Alteromonas].	29.79	574	343	18	8	539	5	560	9e-61	224
rs:WP_005381063	MULTISPECIES: DNA topoisomerase [Veillonella].	27.61	641	391	19	7	598	4	620	9e-61	226
rs:WP_039310260	DNA topoisomerase III [Pectobacterium atrosepticum].	28.26	545	356	13	7	531	4	533	9e-61	224
rs:WP_033186461	DNA topoisomerase III [Pseudoalteromonas sp. PLSV].	29.08	564	359	14	8	548	5	550	9e-61	224
rs:WP_025714542	DNA topoisomerase III [Klebsiella sp. 10982].	28.62	566	367	14	7	552	4	552	9e-61	224
rs:WP_011770752	DNA topoisomerase III [Psychromonas ingrahamii].	28.69	610	404	13	8	601	5	599	9e-61	224
rs:WP_038419141	DNA topoisomerase III [Enterobacter cloacae].	28.47	576	380	15	7	563	4	566	9e-61	224
rs:WP_018355342	DNA topoisomerase III [Pasteurella pneumotropica].	29.04	582	370	17	7	559	4	571	9e-61	224
rs:WP_039262034	MULTISPECIES: DNA topoisomerase III [Enterobacter].	28.12	576	382	14	7	563	4	566	9e-61	224
rs:WP_010430094	DNA topoisomerase III [Enterobacter mori].	28.12	576	382	14	7	563	4	566	1e-60	224
rs:WP_045910241	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	1e-60	224
rs:WP_023343916	DNA topoisomerase III [Enterobacter sp. MGH 16].	28.30	576	381	14	7	563	4	566	1e-60	224
rs:WP_034940995	DNA topoisomerase III [Erwinia mallotivora].	29.17	545	351	13	7	531	4	533	1e-60	224
rs:WP_022647797	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	27.95	576	383	14	7	563	4	566	1e-60	224
rs:WP_035622801	DNA topoisomerase [Hydrogenophaga intermedia].	29.27	550	350	14	7	530	4	540	1e-60	225
rs:WP_032617695	DNA topoisomerase III [Leclercia adecarboxylata].	28.29	562	374	13	7	552	4	552	1e-60	224
rs:WP_014228966	MULTISPECIES: DNA topoisomerase III [Klebsiella].	28.65	562	372	13	7	552	4	552	1e-60	224
rs:WP_006819591	DNA topoisomerase III [Yokenella regensburgei].	28.45	580	375	16	7	563	4	566	1e-60	224
rs:WP_003756869	DNA topoisomerase III [Listeria grayi].	28.38	613	383	17	7	603	6	578	1e-60	225
rs:WP_024908566	DNA topoisomerase III [Enterobacter asburiae].	28.30	576	381	14	7	563	4	566	1e-60	224
rs:WP_042714821	DNA topoisomerase III [Enterobacter sp. B509].	28.12	576	382	14	7	563	4	566	1e-60	224
rs:WP_021325539	DNA topoisomerase III [Photorhabdus temperata].	29.43	547	347	15	7	531	4	533	1e-60	224
rs:WP_012884825	DNA topoisomerase III [Dickeya dadantii].	27.94	562	375	14	7	552	4	551	1e-60	224
rs:WP_038642446	DNA topoisomerase III [Pseudoalteromonas sp. OCN003].	30.48	538	350	14	8	531	5	532	1e-60	224
rs:WP_039816568	DNA topoisomerase [Xanthomonas arboricola].	29.35	552	347	15	7	530	4	540	1e-60	225
rs:WP_012988871	DNA topoisomerase III [Xenorhabdus bovienii].	28.91	543	355	14	7	531	4	533	1e-60	224
rs:WP_012248288	hypothetical protein, partial [Bordetella petrii].	32.59	405	252	9	8	405	5	395	1e-60	218
rs:WP_033757863	DNA topoisomerase III [Pantoea agglomerans].	27.56	566	373	15	7	552	4	552	1e-60	224
rs:WP_041048795	DNA topoisomerase III [Vibrio cholerae].	28.40	567	345	15	8	539	6	546	1e-60	224
rs:WP_021183047	DNA topoisomerase III [Pantoea sp. AS-PWVM4].	28.99	545	352	14	7	531	4	533	1e-60	224
rs:WP_031848119	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	564	363	15	7	548	5	553	1e-60	224
rs:WP_046126935	DNA topoisomerase III [Vibrio cholerae].	28.40	567	345	15	8	539	6	546	1e-60	224
rs:WP_005285122	DNA topoisomerase III [Edwardsiella tarda].	28.32	572	353	19	7	548	4	548	1e-60	224
rs:WP_037349427	DNA topoisomerase III [Selenomonas artemidis].	31.52	552	334	21	5	536	3	530	1e-60	225
rs:WP_042843630	DNA topoisomerase III [Providencia rettgeri].	28.91	543	351	14	8	530	5	532	1e-60	224
rs:WP_010260636	MULTISPECIES: DNA topoisomerase III [Pantoea].	27.56	566	373	15	7	552	4	552	1e-60	224
tr:B1V109_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.20	577	342	18	7	559	5	550	1e-60	225
rs:WP_010890637	protein TrsI [Lactococcus lactis].	29.81	624	387	20	5	603	3	600	1e-60	225
rs:WP_013238995	MULTISPECIES: DNA topoisomerase III [Clostridium].	29.43	615	367	23	7	590	6	584	1e-60	226
rs:WP_029627393	DNA topoisomerase III [Vibrio cholerae].	28.22	567	346	15	8	539	6	546	1e-60	224
rs:WP_038218184	DNA topoisomerase III [Xenorhabdus bovienii].	28.91	543	355	14	7	531	4	533	1e-60	224
rs:WP_031592756	DNA topoisomerase III [Pantoea agglomerans].	27.56	566	373	15	7	552	4	552	1e-60	224
rs:WP_041406328	DNA topoisomerase III, partial [Shewanella denitrificans].	29.30	570	360	13	8	548	5	560	1e-60	224
rs:WP_025578174	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	564	363	15	7	548	5	553	1e-60	224
rs:WP_008824610	DNA topoisomerase III [Haloplasma contractile].	30.48	561	347	17	3	549	2	533	1e-60	225
rs:WP_021430807	DNA topoisomerase III family protein [[Clostridium] bifermentans].	30.73	602	335	22	5	580	4	549	1e-60	225
tr:A0A0D5PRC1_XANCI	SubName: Full=DNA topoisomerase III, bacteria and conjugative plasmid {ECO:0000313|EMBL:AJY91182.1};	30.80	461	282	8	119	552	1	451	1e-60	223
rs:WP_034288830	DNA topoisomerase III [Bacillus sp. 72].	30.12	561	349	18	3	549	2	533	1e-60	225
rs:WP_032080988	DNA topoisomerase III [Vibrio fluvialis].	28.60	563	369	14	7	549	5	554	1e-60	224
rs:WP_047023740	DNA topoisomerase III [Enterobacter sp. GN02174].	28.47	576	380	15	7	563	4	566	1e-60	224
rs:WP_023639754	DNA topoisomerase III [Dickeya zeae].	27.94	562	376	13	7	552	4	552	1e-60	224
rs:WP_029739826	DNA topoisomerase III [Enterobacter asburiae].	28.12	576	382	14	7	563	4	566	1e-60	224
rs:WP_014831514	DNA topoisomerase III [Enterobacter cloacae].	28.47	576	380	15	7	563	4	566	1e-60	224
rs:WP_008915794	DNA topoisomerase III [Providencia sneebia].	28.91	543	351	14	8	530	5	532	1e-60	224
rs:WP_036940411	DNA topoisomerase III [Providencia stuartii].	29.70	542	350	14	7	530	4	532	1e-60	224
rs:WP_033771944	DNA topoisomerase III [Pantoea agglomerans].	27.56	566	373	15	7	552	4	552	1e-60	224
rs:WP_022737202	DNA topoisomerase III [Laceyella sacchari].	29.63	567	351	17	3	549	2	540	1e-60	225
rs:WP_043014029	DNA topoisomerase III [Clostridium perfringens].	31.20	577	342	18	7	559	8	553	1e-60	225
rs:WP_017146088	DNA topoisomerase III [Klebsiella oxytoca].	28.47	562	373	13	7	552	4	552	1e-60	224
rs:WP_021166216	hypothetical protein [Lactococcus lactis].	29.81	624	387	20	5	603	3	600	1e-60	225
rs:WP_023620725	DNA topoisomerase III [Enterobacter sp. T1-1].	28.47	576	380	15	7	563	4	566	1e-60	224
rs:WP_039555145	DNA topoisomerase III [Vibrio vulnificus].	29.46	577	344	18	7	548	5	553	1e-60	224
rs:WP_023332748	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	28.30	576	381	14	7	563	4	566	1e-60	224
rs:WP_038258043	DNA topoisomerase III [Yokenella regensburgei].	28.45	580	375	16	7	563	4	566	2e-60	224
rs:WP_000088632	MULTISPECIES: DNA topoisomerase III [Vibrio].	28.14	565	349	14	8	539	6	546	2e-60	224
rs:WP_005523705	DNA topoisomerase III [Vibrio mimicus].	28.14	565	349	14	8	539	6	546	2e-60	224
rs:WP_042381158	DNA topoisomerase III [Geobacillus kaustophilus].	30.81	555	319	21	7	546	5	509	2e-60	225
rs:WP_040193168	DNA topoisomerase III [Clostridium sp. CL-6].	29.86	576	352	17	7	559	6	552	2e-60	225
rs:WP_005596770	DNA topoisomerase III [Vibrio scophthalmi].	30.90	576	355	17	8	559	5	561	2e-60	224
rs:WP_013097044	DNA topoisomerase III [Enterobacter cloacae].	28.47	576	380	15	7	563	4	566	2e-60	224
rs:WP_015870990	DNA topoisomerase III [Edwardsiella ictaluri].	28.37	564	363	16	7	548	4	548	2e-60	224
rs:WP_033569999	DNA topoisomerase III [Dickeya sp. 2B12].	28.27	566	369	14	7	552	4	552	2e-60	224
rs:WP_034767491	DNA topoisomerase III [Bacillus thermoamylovorans].	30.81	555	320	19	7	546	5	510	2e-60	225
rs:WP_038979877	MULTISPECIES: DNA topoisomerase III [Enterobacter].	28.47	576	380	15	7	563	4	566	2e-60	224
rs:WP_014314712	DNA topoisomerase III [Clostridium sp. BNL1100].	28.82	576	366	13	3	559	2	552	2e-60	225
rs:WP_014903894	DNA topoisomerase III [Desulfosporosinus meridiei].	29.79	611	372	21	5	590	4	582	2e-60	225
rs:WP_035184697	topoisomerase I [Lactobacillus delbrueckii].	30.71	622	382	19	5	603	3	598	2e-60	225
rs:WP_033732847	DNA topoisomerase III [Pantoea vagans].	27.92	566	371	14	7	552	4	552	2e-60	224
rs:WP_032480933	DNA topoisomerase III [Vibrio cholerae].	28.06	563	352	14	8	539	6	546	2e-60	224
rs:WP_034494731	DNA topoisomerase III [Buttiauxella agrestis].	28.47	562	373	14	7	552	4	552	2e-60	224
rs:WP_025983593	DNA topoisomerase III [Xanthomonas axonopodis].	29.34	542	347	14	8	531	5	528	2e-60	225
tr:S7UCG1_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.84	561	323	21	1	546	8	518	2e-60	225
rs:WP_023305946	DNA topoisomerase III [Enterobacter cloacae].	28.12	576	382	14	7	563	4	566	2e-60	224
rs:WP_035604935	DNA topoisomerase III [Edwardsiella tarda].	28.01	564	365	16	7	548	4	548	2e-60	224
rs:WP_027623839	DNA topoisomerase III [Clostridium lundense].	30.18	570	345	19	1	548	1	539	2e-60	225
rs:WP_019829398	DNA topoisomerase III [Vibrio cholerae].	28.22	567	346	15	8	539	6	546	2e-60	224
rs:WP_004112307	DNA topoisomerase III [Klebsiella oxytoca].	28.47	562	373	13	7	552	4	552	2e-60	224
rs:WP_010532073	DNA topoisomerase III [Lentibacillus jeotgali].	31.16	552	337	17	3	539	2	525	2e-60	225
rs:WP_032663739	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	2e-60	223
rs:WP_005419931	DNA topoisomerase III [Aliivibrio fischeri].	29.76	578	348	15	7	548	14	569	2e-60	224
tr:F7S991_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.98	566	356	17	7	552	4	543	2e-60	225
rs:WP_037033921	DNA topoisomerase III [Rahnella sp. WP5].	29.25	547	348	15	7	531	4	533	2e-60	224
rs:WP_025818497	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	564	363	15	7	548	5	553	2e-60	224
tr:Q8XK95_CLOPE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.20	577	342	18	7	559	5	550	2e-60	225
rs:WP_044744310	DNA topoisomerase III [Anoxybacillus sp. ATCC BAA-2555].	30.99	555	318	21	7	546	5	509	2e-60	224
rs:WP_045269436	DNA topoisomerase III [Enterobacter sp. 35730].	28.30	576	381	14	7	563	4	566	2e-60	223
rs:WP_033145248	DNA topoisomerase III [Enterobacter cloacae].	28.12	576	382	14	7	563	4	566	2e-60	223
rs:WP_017372945	DNA topoisomerase III [Enterobacteriaceae bacterium LSJC7].	28.27	566	369	15	7	552	4	552	2e-60	224
rs:WP_004697350	DNA topoisomerase [Veillonella parvula].	27.80	633	400	18	7	598	4	620	2e-60	225
rs:WP_025161293	DNA topoisomerase III [[Clostridium] bifermentans].	30.31	607	331	22	5	580	4	549	2e-60	224
rs:WP_034834689	DNA topoisomerase III [Clostridium perfringens].	31.20	577	342	18	7	559	8	553	2e-60	225
rs:WP_016475404	DNA topoisomerase III [Veillonella sp. HPA0037].	27.46	641	392	19	7	598	4	620	2e-60	225
rs:WP_020334544	DNA topoisomerase III [Vibrio natriegens].	29.08	564	363	15	7	548	5	553	2e-60	224
tr:D2YDR8_VIBMI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.12	576	353	15	1	539	1	552	2e-60	224
rs:WP_038916231	DNA topoisomerase III [Dickeya zeae].	27.94	562	376	13	7	552	4	552	2e-60	223
rs:WP_008500701	MULTISPECIES: DNA topoisomerase III [Enterobacter].	28.30	576	381	14	7	563	4	566	2e-60	223
tr:D2YND5_VIBMI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.14	565	349	14	8	539	9	549	2e-60	224
rs:WP_033779068	DNA topoisomerase III [Pantoea agglomerans].	27.56	566	373	15	7	552	4	552	2e-60	223
rs:WP_045401540	DNA topoisomerase III [Enterobacter asburiae].	28.12	576	382	14	7	563	4	566	2e-60	223
rs:WP_046976083	DNA topoisomerase III [Photorhabdus temperata].	29.17	545	351	14	7	531	4	533	2e-60	223
rs:WP_039266154	DNA topoisomerase III [Enterobacter sp. FB].	28.30	576	381	14	7	563	4	566	2e-60	223
rs:WP_045415135	DNA topoisomerase III [Enterobacter asburiae].	28.30	576	381	14	7	563	4	566	2e-60	223
rs:WP_020878368	DNA topoisomerase III [Desulfococcus multivorans].	29.06	640	387	27	5	603	12	625	2e-60	227
rs:WP_024833195	DNA topoisomerase III [[Clostridium] josui].	28.34	607	389	15	3	590	2	581	2e-60	225
rs:WP_004560603	DNA topoisomerase [Lactobacillus delbrueckii].	30.57	628	375	20	5	603	3	598	2e-60	224
rs:WP_003852758	DNA topoisomerase III [Pantoea agglomerans].	27.56	566	373	15	7	552	4	552	2e-60	223
rs:WP_039386234	DNA topoisomerase III [Pantoea agglomerans].	27.58	562	370	15	7	548	4	548	2e-60	223
rs:WP_000088633	DNA topoisomerase III [Vibrio mimicus].	27.96	565	350	14	8	539	6	546	2e-60	223
rs:WP_013575369	MULTISPECIES: DNA topoisomerase III [Rahnella].	29.74	548	344	17	7	531	4	533	2e-60	223
rs:WP_012139595	DNA topoisomerase III [Marinobacter lipolyticus].	29.12	546	352	14	8	530	5	538	2e-60	225
rs:WP_032674572	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	2e-60	223
rs:WP_009350711	DNA topoisomerase [Selenomonas artemidis].	28.79	587	346	17	8	552	5	561	2e-60	225
rs:WP_045406323	DNA topoisomerase III [Enterobacter asburiae].	28.30	576	381	14	7	563	4	566	2e-60	223
tr:A0A061Q7A3_9VIBR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.79	527	337	13	43	548	24	538	2e-60	223
tr:Q12LJ6_SHEDO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.30	570	360	13	8	548	5	560	2e-60	224
rs:WP_015834119	DNA topoisomerase III [Photorhabdus asymbiotica].	29.17	545	351	14	7	531	4	533	2e-60	223
rs:WP_036837072	DNA topoisomerase III [Photorhabdus temperata].	29.25	547	348	15	7	531	4	533	2e-60	223
rs:WP_038148583	DNA topoisomerase [Veillonella atypica].	27.61	641	391	19	7	598	4	620	2e-60	225
rs:WP_032468723	DNA topoisomerase III [Vibrio mimicus].	28.14	565	349	14	8	539	6	546	2e-60	223
rs:WP_035810237	DNA topoisomerase III [Jeotgalicoccus sp. 13MG44_air].	29.75	568	351	17	7	559	6	540	2e-60	224
rs:WP_032728100	DNA topoisomerase III [Klebsiella oxytoca].	28.47	562	373	13	7	552	4	552	2e-60	223
gpu:CP011591_1167	DNA topoisomerase III [Enterobacter asburiae]	28.12	576	382	14	7	563	4	566	2e-60	223
tr:Q0SSU9_CLOPS	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.20	577	342	18	7	559	8	553	2e-60	225
rs:WP_032651511	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	2e-60	223
rs:WP_004850046	DNA topoisomerase III [Klebsiella oxytoca].	28.47	562	373	13	7	552	4	552	2e-60	223
rs:WP_021432698	DNA topoisomerase III family protein [[Clostridium] bifermentans].	31.75	567	309	20	5	548	4	515	2e-60	224
rs:WP_004911175	DNA topoisomerase III [Providencia rettgeri].	29.02	541	353	13	8	530	5	532	2e-60	223
rs:WP_039693940	DNA topoisomerase III [Dickeya solani].	28.09	566	370	14	7	552	4	552	3e-60	223
tr:A0A081C7G9_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.34	610	377	21	7	595	6	582	3e-60	224
rs:WP_045438429	DNA topoisomerase III [bacterium UASB270].	29.34	610	377	21	7	595	5	581	3e-60	224
rs:WP_020331263	DNA topoisomerase III [Vibrio fluvialis].	28.60	563	369	14	7	549	5	554	3e-60	223
rs:WP_032639806	DNA topoisomerase III [Enterobacter cloacae].	28.12	576	382	14	7	563	4	566	3e-60	223
rs:WP_004203795	MULTISPECIES: DNA topoisomerase III [Klebsiella].	28.65	562	364	14	7	548	4	548	3e-60	223
rs:WP_011231183	DNA topoisomerase III [Geobacillus kaustophilus].	31.71	555	314	22	7	546	5	509	3e-60	224
rs:WP_026680417	DNA topoisomerase III [Bacillus megaterium].	30.85	551	341	16	1	536	1	526	3e-60	224
rs:WP_014883454	MULTISPECIES: DNA topoisomerase III [Enterobacter].	28.30	576	381	14	7	563	4	566	3e-60	223
rs:WP_024551116	MULTISPECIES: DNA topoisomerase III [Cronobacter].	28.55	564	370	14	7	552	4	552	3e-60	223
rs:WP_014826201	DNA topoisomerase III [Desulfosporosinus acidiphilus].	27.82	611	384	19	5	590	4	582	3e-60	224
rs:WP_042748761	topoisomerase I [Lactococcus lactis].	29.65	624	388	20	5	603	3	600	3e-60	224
rs:WP_004724160	DNA topoisomerase III [Vibrio furnissii].	28.42	563	370	14	7	549	5	554	3e-60	223
rs:WP_016941287	DNA topoisomerase III [Dickeya zeae].	27.94	562	376	13	7	552	4	552	3e-60	223
rs:WP_041903320	DNA topoisomerase III [Bacillus thermoamylovorans].	30.99	555	319	20	7	546	5	510	3e-60	224
rs:WP_042262170	DNA topoisomerase III [Clostridium perfringens].	31.02	577	343	18	7	559	8	553	3e-60	224
rs:WP_045135044	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	3e-60	223
rs:WP_025757378	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	15	7	563	4	566	3e-60	223
rs:WP_005841157	DNA topoisomerase III [Mitsuokella multacida].	30.14	554	339	14	8	530	5	541	3e-60	226
rs:WP_041845841	DNA topoisomerase III [Bacillus thermoamylovorans].	31.17	555	318	20	7	546	5	510	3e-60	224
rs:WP_000088631	DNA topoisomerase III [Vibrio sp. RC586].	26.75	628	397	17	8	601	6	604	3e-60	223
rs:WP_036943638	DNA topoisomerase [Pseudobacteroides cellulosolvens].	31.19	561	341	15	8	532	7	558	3e-60	223
rs:WP_046121448	DNA topoisomerase III [Vibrio cholerae].	28.22	567	346	15	8	539	6	546	3e-60	223
tr:L1PX80_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.40	646	396	19	2	598	6	627	3e-60	225
tr:B1BJK1_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.02	577	343	18	7	559	5	550	3e-60	224
rs:WP_033004773	DNA topoisomerase III [Geobacillus sp. WSUCF1].	30.99	555	318	21	7	546	5	509	3e-60	224
rs:WP_008925300	DNA topoisomerase III [Pantoea sp. aB].	27.39	566	374	15	7	552	4	552	3e-60	223
rs:WP_047352559	DNA topoisomerase III [Enterobacter sp. GN02616].	28.47	576	380	15	7	563	4	566	3e-60	223
rs:WP_032636920	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	3e-60	223
rs:WP_004183670	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	3e-60	223
rs:WP_019842061	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	28.37	557	367	11	4	539	1	546	3e-60	223
rs:WP_031390120	DNA topoisomerase III [Clostridium sp. KNHs209].	29.55	616	356	20	8	554	7	613	3e-60	224
rs:WP_017434187	DNA topoisomerase III [Geobacillus caldoxylosilyticus].	29.19	555	364	14	4	544	1	540	3e-60	224
rs:XP_011566445	PREDICTED: DNA topoisomerase 3-like [Plutella xylostella].	28.30	576	381	14	7	563	4	566	3e-60	223
rs:WP_042938256	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	3e-60	223
rs:WP_020959943	DNA topoisomerase III [Geobacillus sp. JF8].	30.25	552	334	19	4	530	1	526	3e-60	224
rs:WP_032438565	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	3e-60	223
rs:WP_026762718	DNA topoisomerase [Selenomonas artemidis].	29.13	587	344	17	8	552	5	561	3e-60	224
rs:WP_038925922	DNA topoisomerase III [Dickeya zeae].	27.94	562	376	13	7	552	4	552	3e-60	223
tr:B1RGM1_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.02	577	343	18	7	559	5	550	3e-60	224
tr:H7CWN7_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.02	577	343	18	7	559	5	550	3e-60	224
rs:WP_023282373	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	3e-60	223
rs:WP_017872293	hypothetical protein [Candidatus Caldatribacterium saccharofermentans].	31.13	559	336	18	7	550	6	530	3e-60	224
rs:WP_015697218	DNA topoisomerase III [Rahnella aquatilis].	29.56	548	345	17	7	531	4	533	3e-60	223
rs:WP_011600633	DNA topoisomerase [Hydrogenophaga intermedia].	29.14	549	351	13	7	530	4	539	3e-60	224
rs:WP_042259147	DNA topoisomerase III [Clostridium perfringens].	31.02	577	343	18	7	559	8	553	3e-60	224
rs:WP_013260124	DNA topoisomerase III [gamma proteobacterium HdN1].	28.37	578	365	17	8	549	5	569	3e-60	223
rs:WP_012423320	DNA topoisomerase III [Clostridium botulinum].	29.85	583	355	19	1	559	1	553	4e-60	224
rs:WP_038904435	DNA topoisomerase III [Dickeya zeae].	27.94	562	376	13	7	552	4	552	4e-60	223
rs:WP_009657658	DNA topoisomerase III [Selenomonas sp. FOBRC9].	29.30	587	343	18	8	552	5	561	4e-60	224
rs:WP_045285254	DNA topoisomerase III [Enterobacter sp. 35699].	28.30	576	381	15	7	563	4	566	4e-60	223
rs:WP_034824013	DNA topoisomerase III [Clostridium perfringens].	31.02	577	343	18	7	559	8	553	4e-60	224
rs:WP_014423558	DNA topoisomerase 3 [Selenomonas ruminantium].	30.63	555	337	16	8	531	5	542	4e-60	225
rs:WP_039459217	DNA topoisomerase III [Photobacterium gaetbulicola].	27.93	623	399	19	8	603	6	605	4e-60	223
rs:WP_014656070	DNA topoisomerase III [Providencia stuartii].	29.52	542	351	14	7	530	4	532	4e-60	223
rs:WP_022989658	DNA topoisomerase III [Marinobacter sp. ES-1].	27.86	542	364	11	8	530	5	538	4e-60	224
rs:WP_011877338	DNA topoisomerase III [Desulfotomaculum reducens].	30.57	579	352	16	5	559	3	555	4e-60	225
rs:WP_017353184	DNA topoisomerase III [Clostridium botulinum].	29.85	583	355	19	1	559	1	553	4e-60	224
rs:WP_004920303	DNA topoisomerase III [Providencia stuartii].	29.52	542	351	14	7	530	4	532	4e-60	223
rs:WP_038270179	DNA topoisomerase III [Xenorhabdus cabanillasii].	28.73	543	356	14	7	531	4	533	4e-60	223
rs:WP_023634313	DNA topoisomerase III [Geobacillus sp. MAS1].	30.81	555	319	21	7	546	5	509	4e-60	223
rs:WP_028012778	DNA topoisomerase III [Enterobacter cloacae].	28.30	576	381	14	7	563	4	566	4e-60	223
rs:WP_020816211	DNA topoisomerase III [[Clostridium] papyrosolvens].	28.50	607	388	15	3	590	2	581	4e-60	224
rs:WP_000197442	DNA topoisomerase III [Vibrio cholerae].	28.80	559	353	16	8	539	6	546	4e-60	223
rs:WP_023318003	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	4e-60	223
rs:WP_025039084	MULTISPECIES: DNA topoisomerase III [Geobacillus].	30.81	555	319	21	7	546	5	509	4e-60	223
rs:WP_020432484	DNA topoisomerase III [Vibrio fluvialis].	28.24	563	371	14	7	549	5	554	4e-60	223
rs:WP_036082282	DNA topoisomerase III [Listeria cornellensis].	29.98	537	336	13	5	532	4	509	4e-60	224
rs:WP_033010165	DNA topoisomerase III [Geobacillus stearothermophilus].	30.99	555	318	21	7	546	5	509	4e-60	223
rs:WP_042265979	DNA topoisomerase III [Clostridium perfringens].	31.02	577	343	18	7	559	8	553	4e-60	224
rs:WP_021285572	DNA topoisomerase III [Clostridium sp. BL8].	29.75	568	350	17	1	548	1	539	4e-60	224
rs:WP_032749499	DNA topoisomerase III [Klebsiella oxytoca].	28.47	562	373	13	7	552	4	552	4e-60	223
rs:WP_005378468	DNA topoisomerase [Veillonella atypica].	27.77	641	390	19	7	598	4	620	4e-60	224
rs:WP_047027173	DNA topoisomerase III [Enterobacter sp. GN02186].	28.30	576	381	14	7	563	4	566	4e-60	223
rs:WP_047368337	DNA topoisomerase III [Enterobacter sp. GN02548].	28.12	576	382	14	7	563	4	566	4e-60	222
rs:WP_038908043	DNA topoisomerase III [Dickeya zeae].	27.94	562	376	13	7	552	4	552	4e-60	223
rs:WP_022613230	DNA topoisomerase III [Vibrio nigripulchritudo].	28.90	564	365	14	7	548	5	554	5e-60	223
rs:WP_034777902	DNA topoisomerase III [Exiguobacterium mexicanum].	31.23	538	336	16	7	530	4	521	5e-60	224
rs:WP_023389097	DNA topoisomerase III [Youngiibacter fragilis].	29.26	605	371	21	7	587	6	577	5e-60	224
rs:WP_044622876	DNA topoisomerase III [Photobacterium gaetbulicola].	29.17	569	361	16	8	552	6	556	5e-60	223
rs:WP_022550047	DNA topoisomerase III [Vibrio nigripulchritudo].	28.90	564	365	14	7	548	5	554	5e-60	223
rs:WP_021067658	DNA topoisomerase III [Exiguobacterium pavilionensis].	31.04	538	337	15	7	530	4	521	5e-60	223
rs:WP_025896327	topoisomerase I, partial [Lactobacillus delbrueckii].	30.60	585	359	18	40	603	40	598	5e-60	223
rs:WP_022600355	DNA topoisomerase III [Vibrio nigripulchritudo].	28.90	564	365	14	7	548	5	554	5e-60	223
rs:WP_045387311	DNA topoisomerase III [Vibrio rotiferianus].	29.26	564	362	15	7	548	5	553	5e-60	223
rs:WP_023329567	MULTISPECIES: DNA topoisomerase III [Klebsiella].	28.29	562	374	13	7	552	4	552	5e-60	223
rs:WP_032650922	MULTISPECIES: DNA topoisomerase III [Enterobacter].	28.12	576	382	14	7	563	4	566	5e-60	222
rs:WP_014204652	DNA topoisomerase III [Vibrio furnissii].	28.42	563	370	14	7	549	5	554	5e-60	223
rs:WP_042147034	DNA topoisomerase III [Paucisalibacillus sp. EB02].	30.87	554	340	18	3	539	2	529	5e-60	224
rs:WP_024523753	DNA topoisomerase III [Edwardsiella hoshinae].	27.84	564	366	16	7	548	4	548	5e-60	222
tr:B1R566_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.02	577	343	18	7	559	5	550	5e-60	224
rs:WP_006522960	DNA topoisomerase III [Desulfotomaculum gibsoniae].	31.67	562	335	19	8	548	7	540	5e-60	224
rs:WP_023311262	DNA topoisomerase III [Enterobacter cloacae].	27.95	576	383	14	7	563	4	566	5e-60	222
rs:WP_006693315	hypothetical protein [Selenomonas infelix].	28.91	550	349	13	8	531	5	538	5e-60	223
rs:WP_042530086	DNA topoisomerase III [Oceanobacillus oncorhynchi].	29.76	551	342	17	3	536	2	524	6e-60	223
rs:WP_026675398	DNA topoisomerase III [Bacillus bogoriensis].	27.78	612	404	16	4	599	1	590	6e-60	223
rs:WP_033837181	MULTISPECIES: DNA topoisomerase III [Xanthomonas].	28.57	616	399	18	8	603	5	599	6e-60	223
rs:WP_001263214	MULTISPECIES: DNA topoisomerase [Enterobacteriaceae].	28.37	557	367	11	4	539	1	546	6e-60	223
rs:WP_045261603	DNA topoisomerase III [Enterobacter sp. 35669].	28.12	576	382	14	7	563	4	566	6e-60	222
rs:WP_010318864	DNA topoisomerase III [Vibrio ordalii].	27.64	615	404	18	8	597	6	604	6e-60	222
rs:WP_044742825	DNA topoisomerase III [Anoxybacillus sp. ATCC BAA-2555].	30.31	551	335	18	4	530	1	526	6e-60	223
rs:WP_044838231	DNA topoisomerase III [Thalassomonas viridans].	30.99	555	337	17	8	531	5	544	6e-60	222
rs:WP_025435565	DNA topoisomerase III [Eubacterium acidaminophilum].	30.72	573	339	20	1	548	1	540	6e-60	224
tr:U2X8N2_GEOKU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.81	555	319	21	7	546	1	505	6e-60	223
gpu:CP011421_1198	DNA topoisomerase III [Klebsiella pneumoniae]	28.65	562	364	14	7	548	4	548	6e-60	222
rs:WP_040226472	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	6e-60	222
rs:WP_045965975	DNA topoisomerase III [Vibrio nigripulchritudo].	28.72	564	366	14	7	548	5	554	6e-60	223
rs:WP_014195788	DNA topoisomerase III [Geobacillus thermoleovorans].	30.81	555	319	21	7	546	5	509	6e-60	223
rs:WP_023289280	MULTISPECIES: DNA topoisomerase III [Klebsiella].	28.65	562	364	14	7	548	4	548	6e-60	222
rs:WP_032431711	DNA topoisomerase III [Klebsiella pneumoniae].	28.29	562	366	14	7	548	4	548	6e-60	222
rs:WP_019530976	hypothetical protein [Dasania marina].	28.50	621	385	17	8	595	5	599	6e-60	222
rs:WP_042351153	DNA topoisomerase III [Bacillus sp. G2(2012b)].	30.15	544	339	17	3	532	2	518	6e-60	223
rs:WP_004196257	DNA topoisomerase III [Klebsiella pneumoniae].	27.63	619	413	13	4	598	1	608	6e-60	223
rs:WP_002980964	DNA topoisomerase [Chryseobacterium gleum].	29.95	571	343	17	7	552	4	542	7e-60	223
rs:WP_029595302	DNA topoisomerase III [Exiguobacterium sp. GIC31].	31.04	538	337	16	7	530	4	521	7e-60	223
rs:WP_032452512	DNA topoisomerase III [Klebsiella sp. 18A069].	28.65	562	364	14	7	548	4	548	7e-60	222
rs:WP_043013202	DNA topoisomerase III [Clostridium perfringens].	31.02	577	343	18	7	559	8	553	7e-60	223
rs:WP_011411189	DNA topoisomerase III [Sodalis glossinidius].	27.78	558	374	13	7	548	4	548	7e-60	222
rs:WP_026327811	DNA topoisomerase [Selenomonas bovis].	30.07	572	327	18	8	532	5	550	7e-60	224
rs:WP_022476560	DNA topoisomerase [Clostridium sp. CAG:273].	30.38	586	337	18	7	532	39	613	7e-60	223
rs:WP_041910472	DNA topoisomerase III [Enterobacter sp. BIDMC 29].	28.12	576	382	14	7	563	4	566	7e-60	222
rs:WP_022607934	DNA topoisomerase III [Vibrio nigripulchritudo].	28.72	564	366	14	7	548	5	554	7e-60	222
rs:WP_021684478	DNA topoisomerase [Selenomonas sp. oral taxon 892].	28.80	559	339	17	8	531	5	539	7e-60	223
rs:WP_035782818	DNA topoisomerase III [Clostridium botulinum].	29.50	583	357	18	1	559	1	553	7e-60	223
rs:WP_013366590	DNA topoisomerase III [Enterobacter lignolyticus].	28.95	563	361	16	7	548	4	548	8e-60	222
rs:WP_004101300	DNA topoisomerase III [Klebsiella oxytoca].	28.11	562	375	13	7	552	4	552	8e-60	222
rs:WP_038415875	DNA topoisomerase III [Enterobacter cloacae].	27.95	576	383	14	7	563	4	566	8e-60	222
rs:WP_004148065	MULTISPECIES: DNA topoisomerase III [Klebsiella].	28.65	562	364	14	7	548	4	548	8e-60	222
rs:WP_035528896	hypothetical protein, partial [Haliea salexigens].	30.18	560	343	17	4	530	1	545	8e-60	221
rs:WP_038354068	DNA topoisomerase III [Eubacterium limosum].	28.64	611	375	17	5	590	6	580	8e-60	223
rs:WP_017768494	hypothetical protein [Streptococcus agalactiae].	32.82	582	347	21	5	563	3	563	8e-60	223
rs:WP_040174316	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	8e-60	222
rs:WP_018933466	hypothetical protein [Gracilibacillus lacisalsi].	31.63	547	324	19	5	532	4	519	8e-60	223
rs:WP_009486072	MULTISPECIES: DNA topoisomerase III [Klebsiella].	28.65	562	364	14	7	548	4	548	8e-60	222
rs:WP_023316738	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	8e-60	222
rs:WP_009637991	DNA topoisomerase III [Serratia sp. M24T3].	28.26	545	356	13	7	531	4	533	8e-60	222
tr:U4P5E3_CLOBB	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.64	577	353	18	7	559	1	548	8e-60	223
rs:WP_032688194	MULTISPECIES: DNA topoisomerase III [Raoultella].	28.62	566	367	14	7	552	4	552	8e-60	222
rs:WP_013145350	DNA topoisomerase III [Geobacillus sp. C56-T3].	30.99	555	318	21	7	546	5	509	9e-60	223
rs:WP_017022826	DNA topoisomerase III [Aliivibrio logei].	29.79	574	361	15	7	552	14	573	9e-60	222
rs:WP_032428827	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	9e-60	222
rs:WP_031942764	DNA topoisomerase III [uncultured bacterium].	28.78	549	353	13	7	530	4	539	9e-60	223
rs:WP_011988435	DNA topoisomerase [Yersinia pseudotuberculosis].	29.52	630	395	18	1	599	1	612	9e-60	222
rs:WP_033827051	DNA topoisomerase III [Bacillus sp. KW-12].	30.97	565	318	21	7	548	5	520	9e-60	223
rs:WP_043052453	DNA topoisomerase [Streptococcus equi].	32.82	582	347	21	5	563	3	563	9e-60	223
rs:WP_044742475	DNA topoisomerase III [Anoxybacillus sp. ATCC BAA-2555].	30.43	562	325	19	7	548	5	520	9e-60	223
rs:WP_032417775	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	9e-60	222
tr:B1BWJ0_CLOPF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.02	577	343	18	7	559	5	550	9e-60	223
rs:WP_032695843	DNA topoisomerase III [Raoultella planticola].	28.62	566	367	14	7	552	4	552	9e-60	222
rs:WP_042840726	DNA topoisomerase III, partial [Salmonella enterica].	28.63	531	352	13	7	521	4	523	9e-60	219
rs:WP_044099716	DNA topoisomerase III [Xanthomonas citri].	28.57	616	399	18	8	603	5	599	9e-60	223
rs:WP_002901390	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	9e-60	222
rs:WP_046878585	DNA topoisomerase III [Klebsiella oxytoca].	28.47	562	373	13	7	552	4	552	1e-59	222
rs:WP_032419855	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	1e-59	222
rs:WP_038807864	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	1e-59	222
rs:WP_025950588	DNA topoisomerase III [Geobacillus thermocatenulatus].	30.99	555	318	21	7	546	5	509	1e-59	223
rs:WP_004140407	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	1e-59	221
rs:WP_015007093	MULTISPECIES: DNA topoisomerase [Lactobacillales].	31.89	624	374	22	5	603	3	600	1e-59	223
tr:G8LKH3_ENTCL	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.84	582	388	14	1	563	4	572	1e-59	221
rs:WP_044362581	DNA topoisomerase III [Vibrio fluvialis].	28.11	562	373	13	7	549	5	554	1e-59	221
rs:WP_041114359	DNA topoisomerase III [Bacillus badius].	31.06	557	346	18	3	548	2	531	1e-59	223
rs:WP_011590864	DNA topoisomerase III [Clostridium perfringens].	31.31	578	340	19	7	559	8	553	1e-59	223
rs:WP_040978776	DNA topoisomerase III [Oceanobacillus sp. S5].	29.56	548	347	16	3	536	2	524	1e-59	223
rs:WP_032472606	DNA topoisomerase III [Vibrio cholerae].	27.89	563	353	14	8	539	6	546	1e-59	221
rs:WP_038539664	DNA topoisomerase III [Bacillus sp. X1(2014)].	29.23	561	333	16	7	548	5	520	1e-59	222
rs:WP_041273944	hypothetical protein, partial [Desulfobacterium autotrophicum].	30.56	553	336	19	7	539	5	529	1e-59	223
rs:WP_019705495	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	1e-59	221
rs:WP_042870424	DNA topoisomerase III [Dickeya sp. NCPPB 569].	27.92	566	371	14	7	552	4	552	1e-59	221
rs:WP_017766990	hypothetical protein, partial [Streptococcus agalactiae].	32.82	582	347	21	5	563	3	563	1e-59	223
rs:WP_045327023	DNA topoisomerase III [Enterobacter asburiae].	28.12	576	382	14	7	563	4	566	1e-59	221
rs:WP_039565798	DNA topoisomerase III [Serratia marcescens].	28.26	545	356	13	7	531	4	533	1e-59	221
rs:WP_007636905	DNA topoisomerase III [Glaciecola psychrophila].	28.60	570	364	15	7	548	4	558	1e-59	221
rs:WP_015061639	DNA topoisomerase [Ralstonia pickettii].	28.78	549	353	12	7	530	4	539	1e-59	222
rs:WP_017048533	DNA topoisomerase III [Vibrio ordalii].	27.48	615	405	18	8	597	6	604	1e-59	221
rs:WP_038020819	DNA topoisomerase III [Tatumella morbirosei].	28.92	567	356	18	7	548	4	548	1e-59	221
rs:WP_004254081	DNA topoisomerase III [Providencia rettgeri].	28.65	541	355	13	8	530	5	532	1e-59	221
rs:WP_023283560	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	1e-59	221
rs:WP_001898889	DNA topoisomerase III, partial [Vibrio cholerae].	28.57	532	321	14	43	539	4	511	1e-59	221
tr:W1HRD3_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.16	510	302	15	8	491	5	496	1e-59	218
rs:WP_037048578	hypothetical protein, partial [Psychromonas sp. SP041].	28.55	613	404	15	8	602	5	601	1e-59	221
rs:WP_020947509	hypothetical protein [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	1e-59	221
rs:WP_044825433	DNA topoisomerase III [Clostridium aceticum].	30.36	639	366	26	7	607	6	603	1e-59	223
rs:WP_036132497	DNA topoisomerase III [Listeriaceae bacterium FSL A5-0209].	29.80	537	337	13	5	532	4	509	1e-59	222
rs:WP_022591550	DNA topoisomerase III [Vibrio nigripulchritudo].	28.72	564	366	14	7	548	5	554	1e-59	221
rs:WP_005490789	DNA topoisomerase III [Pseudoalteromonas luteoviolacea].	29.52	620	391	19	8	599	5	606	1e-59	221
rs:WP_046495771	hypothetical protein [Syntrophomonas zehnderi].	30.81	555	336	19	7	543	5	529	1e-59	222
rs:WP_036060571	DNA topoisomerase III [Listeria weihenstephanensis].	30.28	535	337	12	5	532	4	509	1e-59	222
rs:WP_003019763	MULTISPECIES: hypothetical protein [Enterobacteriaceae].	27.30	619	415	13	4	598	1	608	1e-59	221
rs:WP_000214250	hypothetical protein [Streptococcus agalactiae].	32.65	582	348	21	5	563	3	563	1e-59	222
tr:G9QKK7_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.38	565	345	18	5	548	3	534	2e-59	222
rs:WP_034599166	DNA topoisomerase III [Desulfosporosinus sp. HMP52].	29.13	611	382	18	5	594	4	584	2e-59	222
rs:WP_026739409	DNA topoisomerase III [Lonsdalea quercina].	28.72	564	362	16	7	548	4	549	2e-59	221
rs:WP_013509359	DNA topoisomerase III [Pantoea sp. At-9b].	27.86	603	393	17	7	584	4	589	2e-59	221
rs:WP_040341219	DNA topoisomerase III [Bacillus smithii].	29.38	565	345	18	5	548	6	537	2e-59	222
rs:WP_041101489	DNA topoisomerase III [Bacillus badius].	30.70	557	348	17	3	548	2	531	2e-59	222
rs:WP_023339139	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	2e-59	221
tr:A0A098F5K3_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.82	584	346	22	3	559	2	554	2e-59	221
rs:WP_032711859	DNA topoisomerase III [Enterobacter aerogenes].	28.11	562	375	13	7	552	4	552	2e-59	221
rs:WP_019029803	DNA topoisomerase III [Colwellia piezophila].	30.24	572	352	18	8	548	5	560	2e-59	221
rs:WP_017649217	hypothetical protein [Streptococcus agalactiae].	32.82	582	347	21	5	563	3	563	2e-59	222
rs:WP_027669479	DNA topoisomerase III [Rheinheimera baltica].	26.21	622	418	16	8	603	5	611	2e-59	221
rs:WP_038658888	DNA topoisomerase III [Cedecea neteri].	28.09	566	370	14	7	552	4	552	2e-59	221
rs:WP_039103122	DNA topoisomerase III [Klebsiella variicola].	28.45	566	368	14	7	552	4	552	2e-59	221
rs:WP_047041314	DNA topoisomerase III [Enterobacter aerogenes].	27.94	562	376	13	7	552	4	552	2e-59	221
rs:WP_047364334	DNA topoisomerase III [Enterobacter sp. GN02283].	28.12	576	382	14	7	563	4	566	2e-59	221
rs:WP_005368918	DNA topoisomerase III [Photobacterium angustum].	30.63	542	347	13	8	531	6	536	2e-59	221
rs:WP_032638381	DNA topoisomerase III [Enterobacter sp. EGD-HP1].	28.30	576	381	15	7	563	4	566	2e-59	221
rs:WP_021312943	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	2e-59	221
rs:WP_024252942	DNA topoisomerase [Escherichia coli].	27.46	619	414	13	4	598	1	608	2e-59	221
rs:WP_036805538	DNA topoisomerase III [Photorhabdus luminescens].	28.52	547	352	14	7	531	4	533	2e-59	221
rs:WP_045630122	DNA topoisomerase III [Enterobacter cloacae].	28.12	576	382	14	7	563	4	566	2e-59	221
tr:A0A0D0S1Q1_9BACI	SubName: Full=Anoxybacillus thermarum strain AF/04 contig000014, whole genome shotgun sequence {ECO:0000313|EMBL:KIQ94851.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIQ94851.1};	29.80	537	348	13	7	530	2	522	2e-59	219
rs:WP_039432611	DNA topoisomerase III [Vibrio navarrensis].	27.97	572	359	15	7	548	5	553	2e-59	221
rs:WP_017020022	DNA topoisomerase III [Aliivibrio fischeri].	29.76	578	348	15	7	548	14	569	2e-59	221
rs:WP_045569553	DNA topoisomerase III [Vibrio sp. S234-5].	28.32	572	357	15	7	548	5	553	2e-59	221
rs:WP_034546490	DNA topoisomerase III [Carnobacterium alterfunditum].	31.49	562	345	17	4	548	3	541	2e-59	222
rs:WP_031574346	DNA topoisomerase III [Proteiniclasticum ruminis].	29.44	608	362	22	7	590	6	570	2e-59	222
rs:WP_040133203	DNA topoisomerase III [Providencia stuartii].	29.04	544	351	14	7	530	4	532	2e-59	221
rs:WP_033020754	DNA topoisomerase III [Geobacillus sp. G1w1].	30.13	551	336	18	4	530	1	526	2e-59	222
rs:WP_046621085	DNA topoisomerase III [Klebsiella pneumoniae].	28.45	566	368	14	7	552	4	552	2e-59	221
rs:WP_002448594	DNA topoisomerase III [Staphylococcus hominis].	28.55	564	363	14	7	559	5	539	2e-59	222
rs:WP_002478828	DNA topoisomerase III [Staphylococcus lugdunensis].	28.24	563	366	14	7	559	5	539	2e-59	222
rs:WP_035063636	DNA topoisomerase III [Anoxybacillus sp. SK3-4].	30.56	553	320	20	7	546	5	506	2e-59	221
rs:WP_043966410	DNA topoisomerase III [Anoxybacillus thermarum].	30.69	554	318	21	7	546	5	506	2e-59	221
rs:WP_026821966	DNA topoisomerase III [Arsenophonus nasoniae].	29.87	559	359	15	8	548	6	549	2e-59	221
rs:WP_012160000	DNA topoisomerase III [Alkaliphilus oremlandii].	32.18	550	325	17	7	539	5	523	2e-59	222
tr:A0A0D0Q8E3_9BACI	SubName: Full=Anoxybacillus thermarum strain AF/04 contig000028, whole genome shotgun sequence {ECO:0000313|EMBL:KIQ94273.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIQ94273.1};	30.69	554	318	21	7	546	6	507	2e-59	221
rs:WP_047348900	DNA topoisomerase III [Enterobacter sp. GN03164].	27.95	576	383	14	7	563	4	566	2e-59	220
rs:WP_032422354	DNA topoisomerase III [Klebsiella pneumoniae].	28.70	561	363	14	8	548	5	548	2e-59	221
rs:WP_044737023	DNA topoisomerase III [Geobacillus kaustophilus].	30.13	551	336	18	4	530	1	526	2e-59	222
tr:R5HVF0_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.58	551	334	13	7	532	5	526	2e-59	222
rs:WP_017415049	DNA topoisomerase III [Clostridium tunisiense].	29.58	568	351	17	1	548	1	539	2e-59	222
rs:WP_035065255	DNA topoisomerase III [Anoxybacillus gonensis].	28.16	618	402	19	4	603	1	594	2e-59	222
rs:WP_008807619	MULTISPECIES: DNA topoisomerase III [Klebsiella].	28.45	566	368	14	7	552	4	552	2e-59	221
rs:WP_032114974	DNA topoisomerase III [Arsenophonus endosymbiont of Nilaparvata lugens].	29.34	559	362	15	8	548	6	549	3e-59	220
tr:Q2B0Q7_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.80	547	341	15	7	530	6	532	3e-59	219
rs:WP_037545408	DNA topoisomerase III [Staphylococcus lugdunensis].	28.24	563	366	14	7	559	5	539	3e-59	221
rs:WP_032141116	DNA topoisomerase [Escherichia coli].	27.46	619	414	13	4	598	1	608	3e-59	221
rs:WP_036575330	DNA topoisomerase III [Oceanobacillus picturae].	31.29	572	330	20	3	548	2	536	3e-59	222
rs:WP_037350384	DNA topoisomerase, partial [Selenomonas sp. oral taxon 137].	29.13	587	344	18	8	552	5	561	3e-59	221
rs:WP_005833407	DNA topoisomerase III [Brevibacillus agri].	28.22	613	403	16	4	599	1	593	3e-59	222
rs:WP_012533717	DNA topoisomerase III [Aliivibrio fischeri].	29.58	578	349	15	7	548	14	569	3e-59	221
gp:CP001837_768	DNA topoisomerase III [Staphylococcus lugdunensis HKU09-01]	28.24	563	366	14	7	559	10	544	3e-59	221
rs:WP_031589874	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	3e-59	220
rs:WP_039443542	DNA topoisomerase III [Vibrio navarrensis].	28.20	571	357	15	8	548	6	553	3e-59	221
rs:WP_039696268	DNA topoisomerase [Enterobacter cloacae].	27.64	615	410	13	8	598	5	608	3e-59	221
rs:WP_023363291	DNA topoisomerase III [Escherichia coli].	27.46	619	414	13	4	598	1	608	3e-59	221
rs:WP_017755328	DNA topoisomerase III [Bacillus sp. ZYK].	30.46	568	342	17	5	548	4	542	3e-59	222
rs:WP_009112895	DNA topoisomerase III [Brenneria sp. EniD312].	28.62	545	354	14	7	531	4	533	3e-59	220
rs:WP_021772031	DNA topoisomerase [Mitsuokella sp. oral taxon 131].	29.34	576	365	16	7	561	4	558	3e-59	221
rs:WP_033155036	MULTISPECIES: DNA topoisomerase III [Bacillus].	31.34	568	336	21	3	548	12	547	3e-59	222
tr:A0A0A5LTA1_SERMA	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.26	545	356	13	7	531	4	533	3e-59	220
rs:WP_016160745	MULTISPECIES: DNA topoisomerase III [Klebsiella].	28.45	566	368	14	7	552	4	552	3e-59	220
rs:WP_036414934	DNA topoisomerase III [Morganella morganii].	28.52	547	352	15	7	531	4	533	3e-59	220
rs:WP_023279896	DNA topoisomerase III [Klebsiella pneumoniae].	28.65	562	364	14	7	548	4	548	3e-59	220
rs:WP_032754074	DNA topoisomerase III [Klebsiella pneumoniae].	28.50	565	367	14	8	552	5	552	3e-59	220
rs:WP_023297427	MULTISPECIES: DNA topoisomerase III [Klebsiella].	28.45	566	368	14	7	552	4	552	3e-59	220
rs:WP_004235547	DNA topoisomerase III [Morganella morganii].	28.52	547	352	15	7	531	4	533	3e-59	220
rs:WP_044162603	DNA topoisomerase [Salinibacillus aidingensis].	29.25	629	385	21	7	599	4	608	3e-59	221
rs:WP_020078544	DNA topoisomerase III [Enterobacter aerogenes].	27.94	562	376	13	7	552	4	552	3e-59	220
tr:W7DPX5_9LIST	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.38	613	391	18	7	606	6	583	3e-59	221
rs:WP_034631803	DNA topoisomerase III [Bacillus okhensis].	29.14	628	392	21	7	605	4	607	3e-59	221
rs:WP_032310187	DNA topoisomerase [Escherichia coli].	27.46	619	414	13	4	598	1	608	3e-59	221
rs:WP_036780803	DNA topoisomerase III [Photorhabdus luminescens].	28.34	547	353	14	7	531	4	533	3e-59	220
rs:WP_014184172	DNA topoisomerase III [Desulfosporosinus orientis].	31.17	571	348	19	5	550	4	554	4e-59	222
rs:WP_045411298	DNA topoisomerase III [Enterobacter aerogenes].	27.94	562	376	13	7	552	4	552	4e-59	220
rs:WP_041145117	DNA topoisomerase III [Raoultella ornithinolytica].	28.98	566	365	14	7	552	4	552	4e-59	220
rs:WP_036093033	DNA topoisomerase III [Listeria newyorkensis].	29.61	537	338	13	5	532	4	509	4e-59	221
rs:WP_023519649	topoisomerase [Enterococcus mundtii].	30.29	558	354	14	5	544	3	543	4e-59	221
rs:WP_000197435	DNA topoisomerase III [Vibrio cholerae].	28.80	559	353	16	8	539	6	546	4e-59	220
rs:WP_039073230	DNA topoisomerase III [Bacillus sp. MSP5.4].	31.34	568	336	21	3	548	12	547	4e-59	221
tr:W7RM55_BACLI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.34	568	336	21	3	548	2	537	4e-59	221
rs:WP_017346306	DNA topoisomerase III [Pantoea sp. A4].	28.81	545	353	13	7	531	4	533	4e-59	220
rs:WP_028778686	hypothetical protein [Shimazuella kribbensis].	29.80	557	350	17	4	544	1	532	4e-59	221
rs:WP_036417289	DNA topoisomerase III [Morganella sp. EGD-HP17].	28.52	547	352	15	7	531	4	533	4e-59	220
rs:WP_006705692	DNA topoisomerase III [Candidatus Regiella insecticola].	29.49	546	346	15	8	531	5	533	4e-59	220
tr:A0A0D0RIW4_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.60	554	336	15	5	539	3	521	4e-59	221
tr:A0A0C7JF70_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.34	557	330	16	5	548	4	515	4e-59	221
rs:WP_036734273	DNA topoisomerase III [Peptococcaceae bacterium SCADC1_2_3].	29.79	584	349	22	7	563	5	554	4e-59	221
rs:WP_033078756	DNA topoisomerase III [Thalassotalea sp. ND16A].	28.32	618	384	19	8	590	5	598	4e-59	220
rs:WP_045363723	DNA topoisomerase III [Enterobacter aerogenes].	27.94	562	376	13	7	552	4	552	4e-59	220
rs:WP_007931300	MULTISPECIES: DNA topoisomerase III [Pelosinus].	29.93	568	339	19	7	548	6	540	4e-59	221
rs:WP_029566545	DNA topoisomerase III [Bacillus cibi].	31.68	565	330	20	7	548	6	537	4e-59	221
rs:WP_043926749	DNA topoisomerase III [Bacillus licheniformis].	31.34	568	336	21	3	548	12	547	4e-59	221
rs:WP_034612451	DNA topoisomerase III [Desulfosporosinus sp. Tol-M].	28.17	607	385	18	5	590	4	580	4e-59	221
rs:WP_004435076	DNA topoisomerase III [Bacillus methanolicus].	29.15	614	393	18	7	599	4	596	4e-59	221
rs:WP_047037701	DNA topoisomerase III [Enterobacter aerogenes].	27.94	562	376	13	7	552	4	552	4e-59	220
rs:WP_040528706	DNA topoisomerase III [Grimontia hollisae].	29.43	564	359	16	7	549	5	550	4e-59	219
rs:WP_016927481	DNA topoisomerase III [Serratia marcescens].	28.26	545	356	13	7	531	4	533	5e-59	219
rs:WP_018871403	DNA topoisomerase III [Thioalkalivibrio sp. ALgr3].	30.47	548	346	13	7	540	5	531	5e-59	219
rs:WP_024984278	DNA topoisomerase III [Brevibacillus borstelensis].	27.88	617	399	16	4	599	1	592	5e-59	221
rs:WP_047054042	DNA topoisomerase III [Enterobacter aerogenes].	27.94	562	376	13	7	552	4	552	5e-59	220
rs:WP_045393274	DNA topoisomerase III [Enterobacter aerogenes].	27.94	562	376	13	7	552	4	552	5e-59	220
rs:WP_015461373	MULTISPECIES: DNA topoisomerase III [Edwardsiella].	28.19	564	364	16	7	548	4	548	5e-59	219
rs:WP_037497697	DNA topoisomerase III, partial [Solirubrobacter soli].	29.98	567	351	19	5	548	4	547	5e-59	221
tr:D0I730_GRIHO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.43	564	359	16	7	549	26	571	5e-59	220
rs:WP_005997465	DNA topoisomerase III [Xanthomonas vesicatoria].	27.92	616	403	18	8	603	5	599	5e-59	221
tr:R9TS34_BACLI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	31.16	568	337	21	3	548	4	539	5e-59	221
rs:WP_047079528	DNA topoisomerase III [Enterobacter aerogenes].	27.94	562	376	13	7	552	4	552	5e-59	219
rs:WP_038291301	DNA topoisomerase [[Clostridium] straminisolvens].	31.27	582	359	18	8	555	7	581	5e-59	219
rs:WP_032714745	DNA topoisomerase III [Enterobacter aerogenes].	27.94	562	376	13	7	552	4	552	5e-59	219
rs:WP_015705779	DNA topoisomerase III [Enterobacter aerogenes].	27.94	562	376	13	7	552	4	552	5e-59	219
rs:WP_026563023	DNA topoisomerase III [Bacillus sp. J37].	30.96	562	345	20	3	548	2	536	5e-59	221
rs:WP_032681222	DNA topoisomerase III [Enterobacter sp. BIDMC 30].	27.95	576	383	14	7	563	4	566	6e-59	219
rs:WP_008296568	DNA topoisomerase 3 [Bhargavaea cecembensis].	30.51	544	335	17	3	530	2	518	6e-59	221
rs:WP_002455007	DNA topoisomerase III [Staphylococcus hominis].	28.37	564	364	14	7	559	5	539	6e-59	221
rs:WP_026703297	DNA topoisomerase III [Bacillus aidingensis].	30.70	544	338	15	3	532	2	520	6e-59	221
rs:WP_039465481	DNA topoisomerase III [Vibrio navarrensis].	28.20	571	357	15	8	548	6	553	6e-59	220
rs:WP_003350935	DNA topoisomerase III [Bacillus methanolicus].	30.20	563	325	20	7	548	5	520	6e-59	220
rs:WP_040148465	DNA topoisomerase III [Klebsiella pneumoniae].	28.47	562	365	14	7	548	4	548	6e-59	219
rs:WP_020884435	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	27.95	576	383	14	7	563	4	566	6e-59	219
rs:WP_042892724	DNA topoisomerase III [Enterobacter aerogenes].	27.94	562	376	13	7	552	4	552	6e-59	219
rs:WP_025950702	DNA topoisomerase III [Geobacillus thermocatenulatus].	30.13	551	336	18	4	530	1	526	6e-59	221
rs:WP_015366158	DNA topoisomerase III [Enterobacter aerogenes].	27.94	562	376	13	7	552	4	552	6e-59	219
rs:WP_006704071	DNA topoisomerase III [Candidatus Regiella insecticola].	29.62	547	346	15	7	531	4	533	6e-59	219
rs:WP_039429996	DNA topoisomerase III [Vibrio navarrensis].	28.20	571	357	15	8	548	6	553	6e-59	220
rs:WP_041817152	DNA topoisomerase III [Bacillus licheniformis].	31.16	568	337	21	3	548	12	547	6e-59	221
rs:WP_025204419	DNA topoisomerase III [Enterobacter cloacae].	27.95	576	383	14	7	563	4	566	6e-59	219
rs:WP_003386221	DNA topoisomerase III [Brevibacillus borstelensis].	27.88	617	399	16	4	599	1	592	6e-59	221
rs:WP_013856386	DNA topoisomerase III [Vibrio anguillarum].	27.32	615	406	18	8	597	6	604	6e-59	219
rs:WP_025580044	DNA topoisomerase III [Blautia wexlerae].	29.48	553	336	17	7	532	5	530	6e-59	221
rs:WP_044157940	DNA topoisomerase III [Salinibacillus aidingensis].	30.51	567	343	20	3	548	2	538	6e-59	221
rs:WP_004860845	DNA topoisomerase III [Klebsiella oxytoca].	28.62	566	367	14	7	552	4	552	6e-59	219
rs:WP_015584599	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	28.62	566	367	14	7	552	4	552	6e-59	219
rs:WP_003542029	DNA topoisomerase III [Desulfotomaculum nigrificans].	32.49	554	331	17	5	539	3	532	6e-59	221
rs:WP_022381016	DNA topoisomerase [Ruminococcus sp. CAG:9].	29.48	553	336	17	7	532	5	530	7e-59	221
rs:WP_019418265	DNA topoisomerase III [Anoxybacillus kamchatkensis].	28.66	621	389	19	7	603	4	594	7e-59	220
rs:WP_003356144	DNA topoisomerase III [Clostridium botulinum].	28.99	583	351	20	7	559	6	555	8e-59	221
rs:WP_025910233	DNA topoisomerase III [Bacillus flexus].	28.97	542	339	11	7	544	5	504	8e-59	220
rs:WP_017825375	DNA topoisomerase III, partial [Clostridium botulinum].	29.33	583	358	18	1	559	1	553	8e-59	220
rs:WP_017751809	hypothetical protein [Clostridium tyrobutyricum].	29.34	576	358	19	1	559	1	544	8e-59	220
rs:WP_023302569	DNA topoisomerase III [Klebsiella pneumoniae].	28.47	562	365	14	7	548	4	548	8e-59	219
rs:WP_006318480	DNA topoisomerase III [Anoxybacillus flavithermus].	29.84	553	324	20	7	546	5	506	8e-59	220
rs:WP_027639809	DNA topoisomerase III [Clostridium cadaveris].	29.23	609	373	19	7	590	6	581	8e-59	220
rs:WP_040017237	DNA topoisomerase III [Enterobacter ludwigii].	27.95	576	383	14	7	563	4	566	8e-59	219
rs:WP_010735485	DNA topoisomerase III [Enterococcus mundtii].	30.11	558	355	14	5	544	3	543	9e-59	220
rs:WP_044731338	DNA topoisomerase III [Geobacillus kaustophilus].	30.09	555	322	20	7	546	5	508	9e-59	220
tr:A0A0C7EU68_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.34	557	330	16	5	548	4	515	9e-59	220
rs:WP_013025979	DNA topoisomerase III [Pantoea ananatis].	28.57	546	353	15	7	531	4	533	9e-59	219
rs:WP_044833425	DNA topoisomerase III [Thalassomonas actiniarum].	30.22	556	340	16	8	531	5	544	9e-59	219
rs:WP_028059210	DNA topoisomerase III [Solirubrobacter sp. URHD0082].	29.70	569	354	17	5	548	4	551	9e-59	220
rs:WP_003179052	DNA topoisomerase III [Bacillus licheniformis].	31.34	568	336	21	3	548	13	548	9e-59	220
rs:WP_026648425	DNA topoisomerase III [Blautia wexlerae].	29.48	553	336	17	7	532	5	530	9e-59	220
rs:WP_017045245	DNA topoisomerase III [Vibrio ordalii].	27.32	615	406	18	8	597	6	604	9e-59	219
rs:WP_027631203	DNA topoisomerase III [[Clostridium] cellobioparum].	27.30	608	389	15	5	585	4	585	1e-58	220
tr:A0A0C5PJ08_ECOLX	SubName: Full=Isolate FP671 plasmid pHNFP671, complete sequence {ECO:0000313|EMBL:AJQ17236.1};	27.30	619	415	13	4	598	1	608	1e-58	219
rs:WP_016408372	DNA topoisomerase III [Firmicutes bacterium CAG:102].	29.98	567	346	14	7	552	6	542	1e-58	220
rs:WP_034316017	DNA topoisomerase III [Bacillus simplex].	30.65	584	347	22	3	559	2	554	1e-58	220
rs:WP_036802988	DNA topoisomerase III [Planomicrobium glaciei].	30.05	559	345	17	5	548	3	530	1e-58	220
rs:WP_035417998	hypothetical protein, partial [Ferrovum myxofaciens].	29.86	556	356	15	1	550	1	528	1e-58	217
rs:WP_043031774	DNA topoisomerase III [Clostridium botulinum].	28.77	584	351	20	7	559	6	555	1e-58	220
rs:WP_003486940	DNA topoisomerase III [Clostridium sporogenes].	28.77	584	351	20	7	559	6	555	1e-58	220
rs:WP_045519608	DNA topoisomerase III [Clostridium sporogenes].	28.64	583	353	19	7	559	6	555	1e-58	220
rs:WP_047036902	DNA topoisomerase III [Enterobacter aerogenes].	27.94	562	376	13	7	552	4	552	1e-58	219
rs:WP_011988143	DNA topoisomerase III [Clostridium botulinum].	28.77	584	351	20	7	559	6	555	1e-58	220
rs:WP_015059025	hypothetical protein [Escherichia coli].	27.30	619	415	13	4	598	1	608	1e-58	219
rs:WP_021326569	DNA topoisomerase III, partial [Photorhabdus temperata].	33.33	462	279	14	8	458	5	448	1e-58	215
rs:WP_021906870	DNA topoisomerase [Eubacterium sp. CAG:146].	28.26	552	355	14	7	544	5	529	1e-58	220
rs:WP_047000850	DNA topoisomerase III [Clostridium beijerinckii].	30.67	564	342	16	7	550	6	540	1e-58	220
rs:WP_022257932	DNA topoisomerase [Clostridium sp. CAG:508].	29.02	572	357	15	7	539	6	567	1e-58	219
rs:WP_012848346	DNA topoisomerase III [Edwardsiella tarda].	28.19	564	364	16	7	548	4	548	1e-58	219
rs:WP_017895874	hypothetical protein [Clostridium tyrobutyricum].	29.34	576	358	19	1	559	1	544	1e-58	220
rs:WP_043904536	DNA topoisomerase III [Geobacillus stearothermophilus].	28.62	559	362	15	4	544	1	540	1e-58	220
rs:WP_026557375	DNA topoisomerase III [Bacillus sp. NSP2.1].	28.06	613	404	16	4	599	1	593	1e-58	220
rs:WP_044731386	DNA topoisomerase III [Geobacillus kaustophilus].	29.76	551	338	18	4	530	1	526	1e-58	220
rs:WP_044022747	DNA topoisomerase III [Bacillus sp. SG-1].	30.98	581	349	20	3	559	2	554	1e-58	220
rs:WP_008422242	DNA topoisomerase III [Clostridium sp. Maddingley MBC34-26].	30.05	579	353	19	3	559	2	550	1e-58	220
tr:C0QH35_DESAH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.56	553	336	19	7	539	5	529	1e-58	221
rs:WP_035894586	DNA topoisomerase III [Kluyvera ascorbata].	28.11	562	375	14	7	552	4	552	1e-58	219
rs:WP_034833148	DNA topoisomerase III [Clostridium perfringens].	30.85	577	344	18	7	559	8	553	1e-58	220
rs:WP_027313023	DNA topoisomerase III [Balneatrix alpica].	29.64	550	364	12	7	549	4	537	1e-58	218
rs:WP_003490066	DNA topoisomerase III [Xanthomonas citri].	28.41	616	400	18	8	603	5	599	1e-58	220
rs:WP_009362688	DNA topoisomerase III [Anoxybacillus sp. DT3-1].	28.34	614	400	18	7	603	4	594	1e-58	219
rs:WP_019552090	hypothetical protein [Propionispira raffinosivorans].	29.84	563	360	16	8	550	5	552	1e-58	220
rs:WP_011231305	DNA topoisomerase III [Geobacillus kaustophilus].	30.13	551	336	18	4	530	1	526	1e-58	219
rs:WP_011262202	DNA topoisomerase III [Aliivibrio fischeri].	29.82	570	358	15	7	548	14	569	1e-58	219
rs:WP_007955891	DNA topoisomerase III [Pelosinus fermentans].	29.93	568	339	19	7	548	6	540	1e-58	220
rs:WP_041122970	DNA topoisomerase III [Jeotgalibacillus alimentarius].	30.74	566	344	17	4	548	2	540	1e-58	219
rs:WP_041349811	DNA topoisomerase III [Clostridium botulinum].	28.77	584	351	20	7	559	6	555	1e-58	220
rs:WP_046397481	DNA topoisomerase III [Photorhabdus luminescens].	28.15	547	354	14	7	531	4	533	1e-58	218
rs:WP_012344773	DNA topoisomerase III [Clostridium botulinum].	28.57	581	356	18	7	559	6	555	1e-58	220
rs:WP_012726527	DNA topoisomerase III [Exiguobacterium sp. AT1b].	30.73	537	340	13	7	530	4	521	1e-58	219
rs:WP_022113658	DNA topoisomerase [Clostridium sp. CAG:245].	29.60	581	340	20	7	532	6	572	1e-58	218
tr:E5B1P7_ERWAM	SubName: Full=K03169 DNA topoisomerase III {ECO:0000313|EMBL:CBX79398.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBX79398.1};	31.18	465	292	10	107	553	1	455	1e-58	217
rs:WP_029570080	DNA topoisomerase III [Pantoea ananatis].	28.75	546	352	15	7	531	4	533	1e-58	218
rs:WP_013523745	MULTISPECIES: DNA topoisomerase III [Geobacillus].	30.81	555	319	21	7	546	5	509	1e-58	219
rs:WP_044349470	DNA topoisomerase III [Raoultella ornithinolytica].	28.62	566	367	14	7	552	4	552	1e-58	218
rs:WP_034944768	DNA topoisomerase III [Erwinia oleae].	28.94	546	351	15	7	531	4	533	1e-58	218
rs:WP_033016990	DNA topoisomerase III [Geobacillus stearothermophilus].	30.13	551	336	18	4	530	1	526	1e-58	219
rs:WP_027097876	DNA topoisomerase III [Clostridium paraputrificum].	29.16	607	379	17	3	590	2	576	2e-58	219
rs:WP_029268270	DNA topoisomerase III [Virgibacillus alimentarius].	28.52	554	357	13	3	541	2	531	2e-58	219
rs:WP_045895139	DNA topoisomerase III [Clostridium botulinum].	28.77	584	351	21	7	559	6	555	2e-58	219
rs:WP_003250827	DNA topoisomerase III [Geobacillus thermoglucosidasius].	29.19	555	364	14	4	544	1	540	2e-58	219
rs:WP_038180256	DNA topoisomerase III [Viridibacillus arenosi].	30.09	565	338	19	7	548	6	536	2e-58	219
rs:WP_006783591	DNA topoisomerase III [Turicibacter sanguinis].	31.25	576	339	22	7	559	6	547	2e-58	219
rs:WP_014593831	DNA topoisomerase III [Pantoea ananatis].	28.75	546	352	15	7	531	4	533	2e-58	218
rs:WP_028395884	DNA topoisomerase III [Bacillus sp. FJAT-14578].	29.62	574	349	18	3	555	2	541	2e-58	219
gpu:CP011832_1725	DNA topoisomerase 3 [Geobacillus sp. 12AMOR1]	29.56	548	343	16	4	530	1	526	2e-58	219
rs:WP_031642429	MULTISPECIES: hypothetical protein [Listeria].	29.84	563	348	14	5	544	3	541	2e-58	219
rs:WP_039070763	DNA topoisomerase III [Brevibacillus borstelensis].	29.73	565	352	16	3	548	2	540	2e-58	219
rs:WP_034125070	DNA topoisomerase III [Peptococcaceae bacterium BICA1-7].	29.62	557	342	15	7	539	8	538	2e-58	219
rs:WP_005214016	DNA topoisomerase III [Clostridium celatum].	29.66	580	357	19	1	559	1	550	2e-58	219
rs:WP_041719022	DNA topoisomerase III [Alkaliphilus oremlandii].	30.40	556	335	16	7	539	6	532	2e-58	219
rs:WP_016206725	DNA topoisomerase III [Clostridium sartagoforme].	29.62	574	356	16	7	559	6	552	2e-58	219
rs:WP_009170744	DNA topoisomerase III [Clostridium sp. DL-VIII].	29.24	578	359	16	3	559	2	550	2e-58	219
rs:WP_015378097	DNA topoisomerase III [Serratia marcescens].	28.07	545	357	13	7	531	4	533	2e-58	218
rs:WP_014186245	DNA topoisomerase III [Desulfosporosinus orientis].	28.20	610	383	17	5	590	4	582	2e-58	219
rs:WP_024932262	DNA topoisomerase III, partial [Clostridium botulinum].	28.79	594	352	21	7	563	6	565	2e-58	219
rs:WP_015374805	DNA topoisomerase III [Geobacillus sp. GHH01].	30.99	555	318	21	7	546	5	509	2e-58	219
rs:WP_033065324	DNA topoisomerase III [Clostridium botulinum].	28.64	583	353	20	7	559	6	555	2e-58	219
rs:WP_023603551	DNA topoisomerase III [Aliivibrio logei].	29.62	574	362	15	7	552	5	564	2e-58	218
rs:WP_017042547	DNA topoisomerase III [Vibrio ordalii].	27.32	615	406	18	8	597	6	604	2e-58	218
rs:WP_028043112	DNA topoisomerase III [Candidatus Stoquefichus massiliensis].	29.72	562	353	15	1	548	1	534	2e-58	219
rs:WP_031932480	DNA topoisomerase III [Brevibacillus borstelensis].	29.73	565	352	16	3	548	2	540	2e-58	219
rs:WP_025303086	DNA topoisomerase III [Serratia marcescens].	28.07	545	357	13	7	531	4	533	2e-58	218
tr:A8MG43_ALKOO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.30	561	339	16	7	544	17	548	2e-58	219
rs:WP_010529471	DNA topoisomerase III [Lentibacillus jeotgali].	28.48	625	387	18	6	602	4	596	2e-58	219
rs:WP_042784710	DNA topoisomerase III [Serratia sp. SCBI].	28.07	545	357	13	7	531	4	533	2e-58	218
rs:WP_038152891	DNA topoisomerase [Veillonella montpellierensis].	28.03	628	393	15	7	597	4	609	2e-58	220
rs:WP_013523825	MULTISPECIES: DNA topoisomerase III [Geobacillus].	29.38	548	344	16	4	530	1	526	2e-58	219
rs:WP_012704744	DNA topoisomerase III [Clostridium botulinum].	28.77	584	351	20	7	559	6	555	2e-58	219
rs:WP_004932196	MULTISPECIES: DNA topoisomerase III [Serratia].	28.07	545	357	13	7	531	4	533	2e-58	218
rs:WP_017049114	DNA topoisomerase III [Vibrio ordalii].	27.63	619	399	19	8	597	6	604	2e-58	218
rs:WP_021712669	DNA topoisomerase III [Vibrio ezurae].	28.86	589	368	18	7	564	5	573	2e-58	218
rs:WP_004402186	DNA topoisomerase III [Vibrio nigripulchritudo].	28.55	564	367	14	7	548	5	554	2e-58	218
rs:WP_003388716	DNA topoisomerase III [Brevibacillus borstelensis].	29.73	565	352	16	3	548	2	540	2e-58	219
tr:W1DKN2_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.46	459	277	9	103	537	35	484	2e-58	218
rs:WP_033543275	DNA topoisomerase III [Planococcus sp. CAU13].	30.48	561	340	21	5	548	3	530	2e-58	219
rs:WP_008879173	MULTISPECIES: DNA topoisomerase III [Geobacillus].	30.58	556	319	21	7	546	5	509	2e-58	219
rs:WP_042222299	DNA topoisomerase III [Oceanobacillus manasiensis].	31.15	565	343	19	1	548	1	536	2e-58	219
rs:WP_011666398	DNA topoisomerase III [Bordetella pertussis].	29.78	554	342	14	7	530	4	540	2e-58	219
rs:WP_002597337	DNA topoisomerase III [Clostridium colicanis].	30.12	581	353	21	1	559	1	550	2e-58	219
rs:WP_034915212	DNA topoisomerase III [Erwinia sp. 9145].	28.94	546	351	15	7	531	4	533	2e-58	218
rs:WP_031423395	DNA topoisomerase III [Exiguobacterium sp. NG55].	30.73	537	340	14	7	530	4	521	2e-58	219
rs:WP_013184475	DNA topoisomerase III [Xenorhabdus nematophila].	28.62	545	354	14	7	531	4	533	2e-58	218
rs:WP_037543463	DNA topoisomerase III [Staphylococcus lugdunensis].	27.89	563	368	14	7	559	5	539	2e-58	219
rs:WP_022623227	DNA topoisomerase III [Pantoea ananatis].	28.57	546	353	15	7	531	4	533	2e-58	218
rs:WP_003362991	DNA topoisomerase III [Clostridium botulinum].	28.79	594	352	21	7	563	6	565	2e-58	219
rs:WP_031409354	DNA topoisomerase III [Geobacillus vulcani].	29.76	551	338	18	4	530	1	526	2e-58	219
rs:WP_031943975	DNA topoisomerase [uncultured bacterium pMCBF6].	28.05	549	357	11	7	530	4	539	2e-58	218
rs:WP_010846042	DNA topoisomerase III [Xenorhabdus nematophila].	28.62	545	354	14	7	531	4	533	2e-58	218
rs:WP_043147568	DNA topoisomerase III [Serratia marcescens].	28.07	545	357	13	7	531	4	533	2e-58	218
rs:WP_043142985	DNA topoisomerase III [Serratia marcescens].	28.07	545	357	13	7	531	4	533	2e-58	218
rs:WP_015957841	DNA topoisomerase III [Clostridium botulinum].	28.77	584	351	21	7	559	6	555	2e-58	219
rs:WP_004627448	DNA topoisomerase III, bacteria and conjugative plasmid [[Clostridium] termitidis].	27.30	608	389	15	5	585	4	585	2e-58	219
rs:WP_044504807	DNA topoisomerase III [Megasphaera sp. NP3].	30.07	562	352	17	4	550	1	536	2e-58	219
tr:E6MAJ7_STALU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.89	563	368	14	7	559	10	544	2e-58	219
rs:WP_038065733	hypothetical protein, partial [Thermodesulfovibrio thiophilus].	29.80	614	372	20	7	589	5	590	2e-58	217
rs:WP_033647606	DNA topoisomerase III [Serratia marcescens].	28.07	545	357	13	7	531	4	533	2e-58	218
rs:WP_021503851	DNA topoisomerase III [Serratia marcescens].	28.07	545	357	13	7	531	4	533	2e-58	218
rs:WP_015672564	DNA topoisomerase III [Serratia marcescens].	28.99	545	352	14	7	531	4	533	2e-58	218
rs:WP_012064441	DNA topoisomerase III [Alkaliphilus metalliredigens].	28.37	578	358	18	7	559	6	552	2e-58	219
rs:WP_024933838	DNA topoisomerase III [Clostridium botulinum].	28.77	584	351	20	7	559	6	555	3e-58	219
rs:WP_043332461	DNA topoisomerase III [Cobetia marina].	27.03	629	392	16	7	584	4	616	3e-58	219
rs:WP_033010883	DNA topoisomerase III [Geobacillus stearothermophilus].	30.13	551	336	18	4	530	1	526	3e-58	219
rs:WP_024983039	DNA topoisomerase III [Brevibacillus borstelensis].	29.98	567	348	18	3	548	2	540	3e-58	219
rs:WP_039256074	DNA topoisomerase III [Clostridium novyi].	29.84	563	344	16	7	548	6	538	3e-58	219
rs:WP_004225438	DNA topoisomerase III [Klebsiella pneumoniae].	28.47	562	365	14	7	548	4	548	3e-58	218
rs:WP_017491015	DNA topoisomerase III [gamma proteobacterium WG36].	28.26	545	356	13	7	531	4	533	3e-58	218
rs:WP_045892466	DNA topoisomerase III [Clostridium botulinum].	28.64	583	353	19	7	559	6	555	3e-58	219
rs:WP_039836674	DNA topoisomerase III [Vibrio rumoiensis].	27.78	630	405	18	2	602	3	611	3e-58	218
rs:WP_013400955	MULTISPECIES: DNA topoisomerase III [Geobacillus].	29.01	555	365	14	4	544	1	540	3e-58	219
rs:WP_046898907	DNA topoisomerase III [Serratia marcescens].	28.07	545	357	13	7	531	4	533	3e-58	218
rs:WP_025153076	DNA topoisomerase III [Morganella morganii].	28.52	547	352	15	7	531	4	533	3e-58	218
rs:WP_046932116	DNA topoisomerase III [Xanthomonas gardneri].	28.23	620	396	20	8	603	5	599	3e-58	219
rs:WP_011948909	DNA topoisomerase III [Clostridium botulinum].	28.94	584	350	20	7	559	6	555	3e-58	219
rs:WP_028257636	DNA topoisomerase [Veillonella montpellierensis].	28.18	628	392	16	7	597	4	609	3e-58	219
rs:WP_008223266	DNA topoisomerase III [Vibrionales bacterium SWAT-3].	29.38	565	362	15	7	548	5	555	3e-58	218
rs:WP_033634801	DNA topoisomerase III [Serratia marcescens].	28.44	545	355	14	7	531	4	533	3e-58	217
rs:WP_033643309	DNA topoisomerase III [Serratia marcescens].	28.07	545	357	13	7	531	4	533	3e-58	217
rs:WP_012720525	DNA topoisomerase III [Clostridium botulinum].	28.79	594	352	21	7	563	6	565	3e-58	219
rs:WP_045539505	DNA topoisomerase III [Clostridium botulinum].	28.94	584	350	20	7	559	6	555	3e-58	219
rs:WP_007201633	DNA topoisomerase III [Fictibacillus macauensis].	31.34	552	318	18	7	544	5	509	3e-58	218
tr:A0A0C7I5H8_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.98	557	332	16	5	548	4	515	3e-58	218
rs:WP_036685598	DNA topoisomerase III [Paenibacillus sp. MSt1].	31.49	578	324	19	7	555	5	539	3e-58	218
rs:WP_014520434	DNA topoisomerase III [Clostridium botulinum].	28.47	583	354	20	7	559	6	555	3e-58	219
rs:WP_043063478	DNA topoisomerase III [Aneurinibacillus migulanus].	29.89	562	329	14	5	544	3	521	4e-58	218
rs:WP_003366695	DNA topoisomerase III [Clostridium botulinum].	29.66	563	345	15	7	548	6	538	4e-58	218
rs:WP_041035424	DNA topoisomerase III [Serratia marcescens].	28.07	545	357	13	7	531	4	533	4e-58	217
rs:WP_007784264	DNA topoisomerase III [Brevibacillus sp. CF112].	27.90	613	405	16	4	599	1	593	4e-58	218
rs:WP_033843831	DNA topoisomerase III [Geobacillus subterraneus].	29.95	551	337	18	4	530	1	526	4e-58	218
rs:WP_022544106	DNA topoisomerase III [Bacillus infantis].	28.71	599	381	17	7	580	4	581	4e-58	218
rs:WP_011255183	MULTISPECIES: DNA topoisomerase [Burkholderiales].	29.27	550	350	13	7	530	4	540	4e-58	218
gp:CP000002_471	DNA topoisomerase III [Bacillus licheniformis DSM 13 = ATCC 14580]	31.16	568	337	21	3	548	4	539	4e-58	218
rs:WP_019452756	DNA topoisomerase III [Serratia marcescens].	28.07	545	357	13	7	531	4	533	4e-58	217
rs:WP_018674293	DNA topoisomerase III [Brevibacillus laterosporus].	29.79	564	345	19	7	548	6	540	4e-58	218
rs:WP_046932826	DNA topoisomerase III [Xanthomonas perforans].	27.76	616	404	18	8	603	5	599	4e-58	218
rs:WP_025845013	DNA topoisomerase III [Brevibacillus agri].	28.01	614	403	17	4	599	1	593	4e-58	218
rs:WP_013741022	DNA topoisomerase III [Selenomonas sputigena].	28.52	575	366	13	8	552	5	564	4e-58	218
rs:WP_021322604	MULTISPECIES: DNA topoisomerase III [Geobacillus].	29.95	551	337	18	4	530	1	526	4e-58	218
rs:WP_038877225	DNA topoisomerase III [Serratia marcescens].	28.07	545	357	13	7	531	4	533	4e-58	217
rs:WP_008704037	DNA topoisomerase III [Ruminococcus sp. 5_1_39BFAA].	29.66	553	335	18	7	532	5	530	4e-58	218
rs:WP_014195908	MULTISPECIES: DNA topoisomerase III [Geobacillus].	29.95	551	337	18	4	530	1	526	4e-58	218
rs:WP_020756607	DNA topoisomerase III [Geobacillus sp. WSUCF1].	29.95	551	337	18	4	530	1	526	5e-58	218
rs:WP_006638741	DNA topoisomerase III [Bacillus sonorensis].	31.62	563	337	20	5	548	4	537	5e-58	218
rs:WP_039417357	DNA topoisomerase III [Xanthomonas euvesicatoria].	27.83	618	401	18	8	603	5	599	5e-58	218
rs:WP_021094594	MULTISPECIES: DNA topoisomerase III [Anoxybacillus].	28.08	616	399	18	7	603	4	594	5e-58	218
rs:WP_016885166	DNA topoisomerase III [Bacillus licheniformis].	31.16	568	337	21	3	548	13	548	5e-58	218
rs:WP_041083732	DNA topoisomerase III [Clostridium botulinum].	29.16	583	359	18	1	559	1	553	5e-58	218
sp:TOP3_BACLD	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	31.16	568	337	21	3	548	2	537	5e-58	218
rs:WP_003490483	MULTISPECIES: DNA topoisomerase III [Clostridium].	28.47	583	354	19	7	559	6	555	5e-58	218
rs:WP_023405646	DNA topoisomerase III [Vibrio halioticoli].	28.86	589	368	18	7	564	5	573	5e-58	217
rs:WP_035294111	DNA topoisomerase III [Clostridium sp. KNHs214].	28.89	630	373	24	1	595	1	590	5e-58	218
rs:WP_026867002	DNA topoisomerase III [Jeotgalicoccus marinus].	30.19	573	343	18	7	559	6	541	5e-58	218
rs:WP_046388544	DNA topoisomerase [Streptococcus uberis].	32.47	582	349	21	5	563	3	563	5e-58	218
rs:WP_047340352	DNA topoisomerase [Xanthomonas oryzae].	28.96	549	352	12	7	530	4	539	5e-58	218
rs:WP_010274993	DNA topoisomerase III [Paenibacillus senegalensis].	28.95	570	334	16	5	550	3	525	5e-58	218
rs:WP_046130259	DNA topoisomerase III [Bacillus sp. TH008].	30.74	566	338	20	5	548	4	537	5e-58	218
rs:WP_045720885	DNA topoisomerase III, partial [Salmonella enterica].	28.96	518	341	13	51	552	1	507	5e-58	216
rs:WP_020278829	DNA topoisomerase III [Geobacillus kaustophilus].	29.95	551	337	18	4	530	1	526	5e-58	218
rs:WP_047256201	DNA topoisomerase III [Moellerella wisconsensis].	28.70	540	358	14	7	530	4	532	5e-58	217
tr:A0A0C7GPW0_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.09	565	321	17	5	548	4	515	5e-58	218
rs:WP_027697374	DNA topoisomerase III [Vibrio litoralis].	27.26	631	403	20	4	602	2	608	5e-58	217
rs:WP_038261253	DNA topoisomerase III [[Clostridium] litorale].	29.53	569	336	17	5	544	4	536	6e-58	218
rs:WP_003397193	DNA topoisomerase III [Anoxybacillus flavithermus].	29.84	553	324	20	7	546	5	506	6e-58	218
tr:E4LK90_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.13	587	344	18	8	552	5	561	6e-58	221
rs:WP_026909310	DNA topoisomerase III [Paucisalibacillus globulus].	31.12	556	336	18	3	539	2	529	6e-58	218
rs:WP_046870172	DNA topoisomerase III, partial [Clostridium sporogenes].	28.47	583	354	19	7	559	6	555	6e-58	218
rs:WP_012550681	DNA topoisomerase III [Aliivibrio salmonicida].	29.27	574	364	15	7	552	5	564	6e-58	217
gpu:CP011642_4511	DNA topoisomerase III [Serratia marcescens]	28.07	545	357	13	7	531	4	533	6e-58	216
gp:AE017333_478	DNA topoisomerase III [Bacillus licheniformis DSM 13 = ATCC 14580]	31.16	568	337	21	3	548	5	540	6e-58	218
tr:A0A0C7S3W2_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.98	557	332	16	5	548	4	515	6e-58	218
rs:WP_003371547	DNA topoisomerase III [Clostridium botulinum].	29.33	583	359	18	1	559	1	554	6e-58	218
rs:WP_028396618	DNA topoisomerase III [Bacillus sp. FJAT-14578].	29.35	552	347	16	4	530	1	534	7e-58	218
rs:WP_019120897	DNA topoisomerase III [Brevibacillus massiliensis].	29.95	571	343	19	3	548	2	540	7e-58	218
rs:WP_009330155	MULTISPECIES: DNA topoisomerase III [Bacillus].	31.16	568	337	21	3	548	13	548	7e-58	218
rs:WP_033883715	DNA topoisomerase III [Bacillus subtilis].	30.00	570	326	19	3	539	2	531	7e-58	218
rs:WP_042855301	hypothetical protein [Pseudomonas aeruginosa].	29.60	554	348	11	1	531	1	535	7e-58	218
rs:WP_034061700	hypothetical protein [Pseudomonas aeruginosa].	29.60	554	348	11	1	531	1	535	7e-58	218
rs:WP_011222097	DNA topoisomerase [uncultured bacterium].	29.42	554	344	14	7	530	4	540	7e-58	217
rs:WP_027409811	DNA topoisomerase III [Anoxybacillus tepidamans].	29.16	559	358	15	4	544	1	539	7e-58	218
rs:WP_031943088	DNA processing protein [uncultured bacterium].	29.27	550	350	14	7	530	4	540	8e-58	217
tr:A6CP00_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	30.85	577	347	20	7	559	1	549	8e-58	218
rs:WP_023980686	hypothetical protein [Pseudomonas aeruginosa].	29.60	554	348	11	1	531	1	535	8e-58	218
rs:WP_014386463	DNA topoisomerase III [Comamonas testosteroni].	29.27	550	350	13	7	530	4	540	8e-58	217
rs:WP_026672191	DNA topoisomerase III [Bacillus bogoriensis].	30.48	561	348	16	5	548	4	539	8e-58	218
rs:WP_003149058	DNA topoisomerase III [Pseudomonas aeruginosa].	29.60	554	348	11	1	531	1	535	8e-58	218
rs:WP_026695925	DNA topoisomerase III [Bacillus kribbensis].	29.79	564	343	17	7	548	6	538	8e-58	218
rs:WP_042861184	hypothetical protein [Pseudomonas aeruginosa].	29.60	554	348	11	1	531	1	535	8e-58	218
rs:WP_045855018	DNA topoisomerase III [Raoultella terrigena].	28.62	566	367	14	7	552	4	552	8e-58	216
tr:B6AP75_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.44	557	353	15	8	543	5	542	8e-58	217
tr:A0A0D6DZW6_9LACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:CEN29530.1};	29.43	564	351	17	5	544	3	543	8e-58	217
rs:WP_034743444	DNA topoisomerase III [Bacillus wakoensis].	29.48	631	393	18	4	605	1	608	8e-58	217
rs:WP_045524421	DNA topoisomerase III [Bacillus niacini].	28.76	619	361	22	7	591	5	577	8e-58	217
rs:WP_014870525	DNA topoisomerase III [Marinobacter sp. BSs20148].	28.82	569	366	15	8	552	5	558	9e-58	217
rs:WP_031942852	DNA topoisomerase III [uncultured bacterium].	29.60	554	343	14	7	530	4	540	9e-58	217
rs:WP_013842511	DNA topoisomerase III [Desulfotomaculum ruminis].	30.86	580	352	15	5	559	3	558	1e-57	218
rs:WP_009616856	DNA topoisomerase III [Desulfosporosinus sp. OT].	29.20	589	363	16	5	557	4	574	1e-57	218
tr:M5QU49_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.84	553	324	20	7	546	6	507	1e-57	216
rs:WP_026677990	DNA topoisomerase III [Fictibacillus gelatini].	29.35	552	329	16	7	544	5	509	1e-57	217
rs:WP_014902554	DNA topoisomerase III [Desulfosporosinus meridiei].	30.86	580	344	17	7	550	6	564	1e-57	218
rs:WP_006717153	DNA topoisomerase III [Desulfitobacterium metallireducens].	28.88	599	374	19	7	584	6	573	1e-57	217
rs:WP_031942736	DNA topoisomerase III [uncultured bacterium].	29.42	554	344	14	7	530	4	540	1e-57	217
tr:F3FN33_PSESX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.35	453	282	10	116	549	1	443	1e-57	214
rs:WP_006845464	DNA topoisomerase [Weissella koreensis].	31.18	603	341	24	5	563	3	575	1e-57	217
rs:WP_045635658	DNA topoisomerase III [Peptococcaceae bacterium BRH_c4a].	28.97	580	358	17	7	563	5	553	1e-57	216
rs:WP_017725889	hypothetical protein [Bacillus sp. L1(2012)].	30.12	571	337	20	3	548	2	535	1e-57	217
rs:WP_046832941	DNA topoisomerase [Xanthomonas axonopodis].	29.17	552	348	13	7	530	4	540	1e-57	216
tr:A0A0C7G6G8_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.80	557	333	16	5	548	4	515	1e-57	217
rs:WP_011114056	MULTISPECIES: DNA topoisomerase [Bacteria].	29.60	554	343	14	7	530	4	540	1e-57	216
rs:WP_046373372	DNA topoisomerase III [Serratia liquefaciens].	27.73	541	364	12	7	531	4	533	1e-57	216
rs:WP_006122511	MULTISPECIES: DNA topoisomerase [Proteobacteria].	29.60	554	343	14	7	530	4	540	1e-57	216
rs:WP_006323417	DNA topoisomerase III [Anoxybacillus flavithermus].	27.45	612	408	17	7	603	4	594	1e-57	217
rs:WP_036408089	DNA topoisomerase III [Morganella morganii].	28.34	547	353	15	7	531	4	533	1e-57	216
rs:WP_043543456	hypothetical protein [Pseudomonas aeruginosa].	29.60	554	348	11	1	531	1	535	1e-57	217
rs:WP_045374815	DNA topoisomerase III [Enterobacter aerogenes].	27.94	562	376	13	7	552	4	552	1e-57	216
rs:WP_001235885	DNA topoisomerase [Salmonella enterica].	29.42	554	344	14	7	530	4	540	1e-57	216
rs:WP_031943142	DNA processing protein [uncultured bacterium].	29.60	554	343	14	7	530	4	540	1e-57	216
rs:WP_013145263	DNA topoisomerase III [Geobacillus sp. C56-T3].	29.38	548	344	16	4	530	1	526	1e-57	217
rs:WP_044616212	DNA topoisomerase III [Gynuella sunshinyii].	28.57	581	357	17	7	553	4	560	1e-57	216
rs:WP_034633460	DNA topoisomerase III [Bacillus okhensis].	28.52	561	342	16	5	539	4	531	1e-57	217
rs:WP_045886111	DNA topoisomerase III [Clostridium sporogenes].	28.47	583	354	19	7	559	6	555	1e-57	217
tr:A0A0C7PZI4_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.91	565	322	17	5	548	4	515	1e-57	216
rs:WP_040612006	DNA topoisomerase III, partial [Odoribacter laneus].	30.60	536	327	18	8	531	5	507	1e-57	216
rs:WP_043070206	DNA topoisomerase III [Aneurinibacillus migulanus].	29.72	562	330	14	5	544	3	521	1e-57	216
rs:WP_010243805	DNA topoisomerase III [Acetivibrio cellulolyticus].	26.78	605	397	15	5	590	4	581	1e-57	217
rs:WP_012449561	DNA topoisomerase III [Clostridium botulinum].	29.16	583	360	18	1	559	1	554	1e-57	217
rs:WP_008521801	DNA topoisomerase III [Jonquetella anthropi].	29.00	562	363	13	8	548	5	551	2e-57	216
rs:WP_017012090	DNA topoisomerase III [Enterovibrio calviensis].	29.53	569	352	19	7	549	5	550	2e-57	216
rs:WP_042394020	DNA topoisomerase III [Clostridium sp. JCC].	30.49	574	349	19	7	559	6	550	2e-57	217
rs:WP_012805984	DNA topoisomerase III [Pseudomonas putida].	29.60	554	343	14	7	530	4	540	2e-57	216
rs:WP_022325293	DNA topoisomerase [Clostridium sp. CAG:798].	30.11	558	348	15	7	532	5	552	2e-57	214
rs:WP_025121009	MULTISPECIES: DNA topoisomerase III [Serratia].	27.89	545	358	13	7	531	4	533	2e-57	215
rs:WP_034861907	DNA topoisomerase III [Enterobacteriaceae bacterium B14].	28.35	568	366	16	7	552	4	552	2e-57	215
rs:WP_001094108	hypothetical protein [Bacillus cereus].	30.61	575	347	16	5	548	3	556	2e-57	217
rs:WP_035663412	DNA topoisomerase III [Bacillus akibai].	29.00	562	358	16	3	548	2	538	2e-57	216
rs:WP_032088751	DNA topoisomerase III [Bacillus aquimaris].	29.53	569	360	16	5	559	4	545	2e-57	216
tr:A0A0C7GEP2_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.80	557	333	16	5	548	4	515	2e-57	216
rs:WP_036832004	DNA topoisomerase III, partial [Photobacterium sanctipauli].	28.60	563	363	15	8	548	6	551	2e-57	214
rs:WP_036864764	DNA topoisomerase III [Porphyromonas sp. COT-108 OH2963].	31.42	557	326	20	7	539	2	526	2e-57	216
rs:WP_032910851	DNA topoisomerase III [Yersinia frederiksenii].	27.89	545	358	13	7	531	4	533	2e-57	215
rs:WP_028723486	DNA topoisomerase III [Pantoea ananatis].	28.39	546	354	15	7	531	4	533	2e-57	215
rs:WP_026825790	DNA topoisomerase III [Exiguobacterium marinum].	30.54	537	341	13	7	530	4	521	2e-57	216
rs:WP_021804264	DNA topoisomerase III [Clostridium intestinale].	28.50	621	385	19	1	598	1	585	2e-57	216
rs:WP_004890695	DNA topoisomerase III [Anoxybacillus flavithermus].	27.69	614	410	15	4	603	1	594	2e-57	216
rs:WP_025842430	DNA topoisomerase III [Porphyromonas gingivicanis].	29.23	633	368	26	7	601	2	592	2e-57	214
tr:H1DJY9_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.60	536	327	18	8	531	5	507	2e-57	216
rs:WP_047073258	DNA topoisomerase III [Brevibacillus formosus].	30.47	571	341	21	3	548	2	541	2e-57	216
rs:WP_024910835	DNA topoisomerase III [Serratia fonticola].	28.26	545	356	13	7	531	4	533	2e-57	215
rs:WP_022168149	DNA topoisomerase III [Clostridium sp. CAG:221].	29.56	592	342	21	1	559	1	550	2e-57	216
rs:WP_036883579	DNA topoisomerase III [Porphyromonas gingivicanis].	29.23	633	368	26	7	601	2	592	2e-57	214
rs:WP_017012778	DNA topoisomerase III [Enterovibrio calviensis].	29.35	569	353	19	7	549	5	550	2e-57	215
rs:WP_035048305	DNA topoisomerase III [Anoxybacillus sp. KU2-6(11)].	29.84	553	324	20	7	546	5	506	3e-57	216
rs:WP_022048204	DNA topoisomerase III [Odoribacter laneus CAG:561].	30.78	536	326	18	8	531	5	507	3e-57	216
rs:WP_022066773	DNA topoisomerase III [Blautia sp. CAG:257].	28.78	549	341	14	7	532	5	526	3e-57	216
rs:WP_042199330	DNA topoisomerase III, partial [Escherichia coli].	29.28	502	329	12	67	552	8	499	3e-57	214
rs:WP_007391353	DNA topoisomerase [Megasphaera sp. UPII 199-6].	30.11	548	345	14	4	531	1	530	3e-57	216
rs:WP_020156037	hypothetical protein [Caldibacillus debilis].	29.66	553	328	19	7	546	5	509	3e-57	216
rs:WP_046893476	DNA topoisomerase III [Morganella morganii].	28.10	548	353	16	7	531	4	533	3e-57	215
rs:WP_004581684	DNA topoisomerase III [Marinobacter nanhaiticus].	26.90	539	370	12	7	531	4	532	3e-57	216
rs:WP_009381396	DNA topoisomerase [Megasphaera genomosp. type_1].	30.11	548	345	14	4	531	1	530	3e-57	216
rs:WP_020492504	DNA topoisomerase III [Dehalobacter sp. FTH1].	28.55	578	363	16	7	563	5	553	3e-57	215
rs:WP_039075817	DNA topoisomerase III [Bacillus sp. MSP13].	30.66	574	317	22	3	539	2	531	3e-57	216
tr:A0A0A1S5R5_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.91	565	322	17	5	548	4	515	3e-57	216
rs:WP_017089851	DNA topoisomerase III [Vibrio splendidus].	28.98	566	363	15	7	548	5	555	3e-57	215
rs:WP_015374908	DNA topoisomerase I [Geobacillus sp. GHH01].	29.76	551	338	18	4	530	1	526	3e-57	216
rs:WP_046514894	DNA topoisomerase III [Bacillus sp. SA1-12].	30.84	548	335	16	4	530	1	525	3e-57	216
rs:WP_014827249	DNA topoisomerase III [Desulfosporosinus acidiphilus].	29.93	558	362	15	7	550	6	548	3e-57	216
rs:WP_009645530	DNA topoisomerase III [Selenomonas sp. CM52].	29.13	563	342	14	8	532	5	548	3e-57	216
rs:WP_011255049	DNA topoisomerase [Aromatoleum aromaticum].	28.98	566	365	13	7	548	4	556	3e-57	215
rs:WP_037399017	MULTISPECIES: DNA topoisomerase III [Serratia].	27.71	545	359	13	7	531	4	533	3e-57	214
rs:WP_013779520	DNA topoisomerase III [Tepidanaerobacter acetatoxydans].	30.23	569	346	19	3	548	2	542	3e-57	216
rs:WP_033118340	DNA topoisomerase III [Intestinimonas butyriciproducens].	28.86	589	345	20	5	559	4	552	3e-57	216
rs:WP_039257876	DNA topoisomerase III [Clostridium botulinum].	30.12	571	344	18	1	548	1	539	3e-57	216
rs:WP_033022586	DNA topoisomerase III [Geobacillus sp. G1w1].	29.60	554	327	19	7	546	5	509	4e-57	215
rs:WP_023008797	DNA topoisomerase III [Marinobacter sp. EVN1].	28.97	542	358	11	8	530	5	538	4e-57	216
rs:WP_042536416	DNA topoisomerase III [Anoxybacillus ayderensis].	29.82	560	315	19	7	546	5	506	4e-57	215
rs:WP_037574799	DNA topoisomerase III [Staphylococcus chromogenes].	28.77	563	363	14	7	559	5	539	4e-57	215
rs:WP_035051234	DNA topoisomerase III [Carnobacterium pleistocenium].	31.60	557	345	17	7	548	5	540	4e-57	215
rs:WP_043859254	DNA topoisomerase III [Staphylococcus aureus].	31.12	556	343	17	5	544	3	534	4e-57	215
rs:WP_034598761	DNA topoisomerase III [Desulfosporosinus sp. HMP52].	31.61	579	341	20	7	550	6	564	4e-57	216
rs:WP_003347899	DNA topoisomerase III [Bacillus methanolicus].	29.66	563	328	20	7	548	5	520	4e-57	215
rs:WP_019416613	DNA topoisomerase III [Anoxybacillus kamchatkensis].	29.84	553	324	20	7	546	5	506	4e-57	215
rs:WP_017174848	DNA topoisomerase III [Staphylococcus hominis].	28.57	567	359	16	7	559	5	539	4e-57	215
rs:WP_016266194	DNA topoisomerase III [Yersinia enterocolitica].	27.71	545	359	13	7	531	4	533	4e-57	214
rs:WP_036659482	DNA topoisomerase III [Paenisporosarcina sp. HGH0030].	28.34	561	359	18	3	548	2	534	4e-57	215
rs:WP_021806609	DNA topoisomerase III [Serratia fonticola].	27.71	545	359	13	7	531	4	533	4e-57	214
rs:WP_044143582	hypothetical protein, partial [Succinimonas amylolytica].	27.70	556	345	17	7	532	4	532	4e-57	213
rs:WP_026742443	DNA topoisomerase III [Lonsdalea quercina].	28.55	564	363	16	7	548	4	549	4e-57	214
rs:WP_038233707	DNA topoisomerase III [Xenorhabdus szentirmaii].	28.55	543	357	14	7	531	4	533	5e-57	214
rs:WP_008430415	DNA topoisomerase III [Planococcus donghaensis].	31.15	565	337	22	1	548	1	530	5e-57	215
rs:WP_004430385	MULTISPECIES: DNA topoisomerase III [Bacillus subtilis group].	29.14	556	349	16	3	539	2	531	5e-57	215
rs:WP_021620860	DNA topoisomerase [Aneurinibacillus aneurinilyticus].	29.36	562	332	15	5	544	3	521	5e-57	215
rs:WP_030034462	DNA topoisomerase III [Clostridium botulinum].	28.30	583	355	19	7	559	6	555	5e-57	215
rs:WP_037541604	DNA topoisomerase III [Staphylococcus sp. M0480].	28.57	567	359	16	7	559	5	539	5e-57	215
rs:WP_015893196	DNA topoisomerase III [Brevibacillus brevis].	30.47	571	341	21	3	548	2	541	5e-57	215
rs:WP_036145124	DNA topoisomerase III [Lysinibacillus sp. BF-4].	29.93	558	349	17	7	548	6	537	5e-57	215
rs:WP_011013284	TraE protein [uncultured bacterium].	29.27	550	350	14	7	530	4	540	5e-57	215
gp:CP009679_388	DNA topoisomerase 3 [Bacillus methylotrophicus]	30.23	559	339	19	3	539	10	539	5e-57	215
rs:WP_013813220	MULTISPECIES: DNA topoisomerase III [Serratia].	28.28	541	361	12	7	531	4	533	5e-57	214
rs:WP_034122483	DNA topoisomerase III [Peptococcaceae bacterium BICA1-7].	29.56	592	339	20	7	563	5	553	5e-57	215
rs:WP_039771836	DNA topoisomerase III [Clostridium diolis].	29.53	579	356	19	3	559	2	550	5e-57	215
rs:WP_004632114	DNA topoisomerase III [Gemella morbillorum].	29.55	572	327	16	5	548	3	526	5e-57	215
rs:WP_034688246	DNA topoisomerase [Enterococcus mundtii].	29.93	558	356	15	5	544	3	543	5e-57	215
rs:WP_038229473	DNA topoisomerase III [Vibrio sp. ER1A].	29.08	564	363	15	7	548	5	553	6e-57	214
rs:WP_007062346	DNA topoisomerase III [Clostridium carboxidivorans].	27.92	616	374	19	7	590	6	583	6e-57	215
rs:WP_035047422	DNA topoisomerase III [Anoxybacillus sp. KU2-6(11)].	28.20	539	360	12	4	530	1	524	6e-57	215
rs:WP_045102431	DNA topoisomerase III [Aliivibrio wodanis].	29.65	570	359	15	7	548	5	560	6e-57	214
rs:WP_010830988	DNA topoisomerase III [Enterococcus faecalis].	29.12	594	358	17	5	563	3	568	6e-57	215
rs:WP_033025446	DNA topoisomerase III [Geobacillus sp. CAMR5420].	29.76	551	338	18	4	530	1	526	6e-57	215
tr:L5MM22_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	30.35	570	347	20	1	548	5	546	6e-57	215
rs:WP_039259411	DNA topoisomerase III [Clostridium botulinum].	30.12	571	344	18	1	548	1	539	6e-57	215
rs:WP_045467535	DNA topoisomerase III [Burkholderiales bacterium GJ-E10].	29.85	546	343	14	7	537	4	524	6e-57	215
rs:WP_006322602	DNA topoisomerase III [Serratia plymuthica].	27.73	541	364	12	7	531	4	533	6e-57	214
rs:WP_031409582	DNA topoisomerase III [Geobacillus vulcani].	29.66	553	328	18	7	546	5	509	6e-57	214
rs:WP_032495545	DNA processing protein, DNA topoisomerase [uncultured bacterium].	29.09	550	351	14	7	530	4	540	6e-57	214
rs:WP_006070054	DNA topoisomerase III [Vibrio shilonii].	29.20	572	352	16	7	548	5	553	6e-57	214
rs:WP_038461743	MULTISPECIES: DNA topoisomerase III [Bacillus].	30.23	559	339	19	3	539	2	531	7e-57	215
rs:WP_026887816	DNA topoisomerase III [Clostridium beijerinckii].	29.58	578	356	20	3	559	2	549	7e-57	215
rs:WP_021481725	DNA topoisomerase III [Bacillus sp. EGD-AK10].	30.18	570	325	18	3	539	2	531	7e-57	215
rs:WP_029163365	DNA topoisomerase III [Clostridium scatologenes].	27.92	616	374	19	7	590	6	583	7e-57	215
rs:WP_039229157	DNA topoisomerase III [Clostridium haemolyticum].	30.12	571	344	18	1	548	1	539	7e-57	215
rs:WP_002580164	DNA topoisomerase III [Clostridium butyricum].	28.30	576	354	18	7	559	6	545	7e-57	215
rs:WP_041086883	DNA topoisomerase III [Jeotgalibacillus soli Cunha et al. 2012].	30.70	557	337	18	5	539	4	533	7e-57	215
rs:WP_015063384	DNA topoisomerase [Burkholderia cepacia].	29.09	550	351	14	7	530	4	540	7e-57	214
rs:WP_039971892	DNA topoisomerase III [Brevibacillus agri].	30.46	568	345	20	3	548	2	541	7e-57	215
tr:S2Y1I5_9BACL	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.04	560	362	16	3	548	48	580	7e-57	215
rs:WP_025436673	DNA topoisomerase [Eubacterium acidaminophilum].	29.91	585	369	15	8	557	7	585	7e-57	214
rs:WP_016599634	DNA topoisomerase III, partial [Yersinia pestis].	27.71	545	359	13	7	531	4	533	7e-57	213
rs:WP_046405598	DNA topoisomerase III [Odoribacter sp. N15.MGS-14].	30.48	538	325	19	8	531	5	507	7e-57	214
rs:WP_011785988	DNA topoisomerase III [Marinobacter hydrocarbonoclasticus].	28.78	542	359	11	8	530	5	538	7e-57	215
rs:WP_014421986	DNA topoisomerase III [Marinobacter hydrocarbonoclasticus].	28.78	542	359	11	8	530	5	538	7e-57	215
rs:WP_046720776	DNA topoisomerase III [Bacillus coagulans].	30.04	546	344	18	3	530	2	527	8e-57	214
rs:WP_035202627	DNA topoisomerase III [Bacillus clausii].	28.49	558	366	14	4	544	1	542	8e-57	214
rs:WP_026557999	DNA topoisomerase III [Bacillus sp. NSP2.1].	30.46	568	345	20	3	548	2	541	8e-57	215
rs:WP_046461889	DNA topoisomerase III [Comamonas testosteroni].	29.55	572	359	16	8	552	5	559	8e-57	215
rs:WP_009766667	DNA topoisomerase III [Sporosarcina newyorkensis].	28.89	578	353	15	7	555	4	552	8e-57	214
tr:A0A0C7RH49_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.91	565	322	17	5	548	4	515	8e-57	214
rs:WP_038673289	DNA topoisomerase III [Pelosinus sp. UFO1].	30.04	566	349	16	3	548	2	540	8e-57	214
rs:WP_039232415	DNA topoisomerase III [Bacillus thermotolerans].	29.84	553	356	16	7	544	4	539	8e-57	214
rs:WP_012145443	MULTISPECIES: DNA topoisomerase III [Serratia].	27.71	545	359	13	7	531	4	533	8e-57	213
rs:WP_036867434	DNA topoisomerase III [Porphyromonas canoris].	31.12	556	329	19	7	539	2	526	9e-57	214
rs:WP_007783982	DNA topoisomerase III [Brevibacillus sp. CF112].	30.46	568	345	20	3	548	2	541	9e-57	214
rs:WP_032551967	DNA topoisomerase III [Vibrio fortis].	29.03	565	364	15	7	548	5	555	9e-57	213
tr:C4U453_YERAL	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.89	545	358	13	7	531	5	534	9e-57	213
rs:WP_039285186	DNA topoisomerase III [Clostridium botulinum].	29.48	563	346	15	7	548	6	538	9e-57	214
rs:WP_033922359	topoisomerase I [Enterococcus faecalis].	31.69	587	355	20	3	563	2	568	9e-57	214
rs:WP_016742873	DNA topoisomerase III [Brevibacillus brevis].	30.47	571	341	21	3	548	2	541	9e-57	214
rs:WP_027201773	DNA topoisomerase III [Butyricimonas virosa].	29.78	544	337	18	8	539	5	515	1e-56	214
rs:WP_044551747	DNA topoisomerase III [Serratia liquefaciens].	27.54	541	365	12	7	531	4	533	1e-56	213
rs:WP_003414618	DNA topoisomerase III [Clostridium butyricum].	28.30	576	354	18	7	559	6	545	1e-56	214
rs:WP_042839186	DNA topoisomerase III [Yersinia aldovae].	27.89	545	358	13	7	531	4	533	1e-56	213
rs:WP_039282953	DNA topoisomerase III [Clostridium botulinum].	30.04	566	341	19	8	532	7	558	1e-56	214
tr:A0A078M9U1_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.93	558	349	17	7	548	6	537	1e-56	214
rs:WP_045144547	DNA topoisomerase III [Clostridium butyricum].	28.30	576	354	18	7	559	6	545	1e-56	214
rs:WP_044743437	DNA topoisomerase III [Anoxybacillus sp. ATCC BAA-2555].	29.48	563	350	17	4	548	1	534	1e-56	214
rs:WP_010494059	DNA topoisomerase III [Paenibacillus elgii].	31.61	579	322	20	7	555	5	539	1e-56	214
rs:WP_026564446	DNA topoisomerase III [Bacillus sp. UNC41MFS5].	28.34	561	338	16	7	548	5	520	1e-56	214
rs:WP_016680565	DNA topoisomerase III, partial [Yersinia pestis].	27.71	545	359	13	7	531	4	533	1e-56	212
rs:WP_041895902	DNA topoisomerase III [Clostridium beijerinckii].	29.36	579	357	19	3	559	2	550	1e-56	214
rs:WP_028672238	DNA topoisomerase III [Saccharospirillum impatiens].	28.82	569	364	14	7	548	4	558	1e-56	213
rs:WP_008984953	DNA topoisomerase III [Alishewanella agri].	30.32	587	340	20	8	552	5	564	1e-56	213
rs:WP_002466483	DNA topoisomerase III [Staphylococcus warneri].	29.05	599	376	18	7	590	5	569	1e-56	214
rs:WP_036847223	DNA topoisomerase III [Porphyromonas sp. COT-108 OH1349].	30.94	556	330	19	7	539	2	526	1e-56	213
rs:WP_027635678	DNA topoisomerase III [Clostridium butyricum].	28.30	576	354	18	7	559	6	545	1e-56	214
rs:WP_023975063	DNA topoisomerase III [Clostridium pasteurianum].	29.36	579	357	19	3	559	2	550	1e-56	214
rs:WP_013379324	DNA topoisomerase III [Eubacterium limosum].	28.81	611	374	18	5	590	6	580	1e-56	214
rs:WP_034132827	DNA topoisomerase [Peptococcaceae bacterium BICA1-8].	29.49	641	395	19	8	603	7	635	1e-56	213
rs:WP_024535645	DNA topoisomerase III [Sporosarcina sp. EUR3 2.2.2].	28.95	563	354	19	3	548	2	535	1e-56	214
rs:WP_042661428	DNA topoisomerase III [Yersinia enterocolitica].	27.71	545	359	13	7	531	4	533	1e-56	213
tr:C9LYN3_SELS3	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.84	541	343	12	42	552	26	554	1e-56	214
tr:A0A077VSS3_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.59	619	388	20	7	606	5	588	1e-56	214
rs:WP_036790296	DNA topoisomerase III [Porphyromonas canoris].	31.12	556	329	19	7	539	2	526	1e-56	213
rs:WP_011798734	DNA topoisomerase [Acidovorax sp. JS42].	28.91	550	352	15	7	530	4	540	1e-56	214
rs:WP_017056476	DNA topoisomerase III [Vibrio kanaloae].	29.03	565	364	15	7	548	5	555	1e-56	213
rs:WP_016793847	DNA topoisomerase III [Vibrio cyclitrophicus].	28.80	566	364	15	7	548	5	555	1e-56	213
rs:WP_016596683	DNA topoisomerase III, partial [Yersinia pestis].	27.71	545	359	13	7	531	4	533	1e-56	212
rs:WP_040227552	DNA topoisomerase III, partial [Bhargavaea cecembensis].	29.56	548	340	19	3	532	2	521	1e-56	213
rs:WP_010789663	IncP-type DNA topoisomerase III TraE [Bacillus atrophaeus].	29.14	556	349	16	3	539	2	531	1e-56	214
rs:WP_015382801	DNA topoisomerase III [Bacillus subtilis].	30.09	575	328	19	3	544	2	535	1e-56	214
rs:WP_041502811	MULTISPECIES: DNA topoisomerase III [unclassified Porphyromonadaceae].	30.24	539	331	17	8	534	5	510	1e-56	214
rs:WP_023011009	DNA topoisomerase III [Marinobacter sp. EN3].	28.78	542	359	11	8	530	5	538	1e-56	214
rs:WP_022992872	DNA topoisomerase III [Marinobacter sp. C1S70].	28.60	542	360	11	8	530	5	538	1e-56	214
rs:WP_017697341	DNA topoisomerase III [Bacillus subtilis].	30.00	570	326	18	3	539	2	531	1e-56	214
rs:WP_032817148	DNA topoisomerase III [Yersinia rohdei].	27.52	545	360	13	7	531	4	533	1e-56	213
tr:A0A098EJ80_9BACL	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.55	557	356	14	5	548	3	530	1e-56	214
rs:WP_031411082	DNA topoisomerase III [Brevibacillus laterosporus].	29.43	564	347	19	7	548	6	540	1e-56	214
rs:WP_000766775	DNA topoisomerase III [Bacillus cereus].	30.43	539	343	18	7	530	4	525	1e-56	214
rs:WP_006520575	DNA topoisomerase III [Desulfotomaculum gibsoniae].	31.13	575	346	20	7	559	5	551	1e-56	214
rs:WP_016783801	DNA topoisomerase III [Vibrio cyclitrophicus].	28.80	566	364	15	7	548	5	555	1e-56	213
rs:WP_025752281	DNA topoisomerase III [Bacillus flexus].	29.43	547	330	14	7	544	5	504	1e-56	213
rs:WP_022461978	DNA topoisomerase [Blautia sp. CAG:37].	27.89	563	356	14	5	544	3	538	1e-56	214
rs:WP_036661964	DNA topoisomerase III [Paenibacillus sp. FSL H8-457].	29.35	627	362	19	7	602	5	581	1e-56	214
rs:WP_004390915	DNA topoisomerase III [Yersinia kristensenii].	27.71	545	359	13	7	531	4	533	1e-56	213
rs:WP_029283165	DNA topoisomerase III [Bacillus indicus].	30.18	560	345	17	7	548	6	537	1e-56	214
rs:WP_040084142	DNA topoisomerase 3 [Bacillus sp. A053].	30.00	570	326	18	3	539	2	531	1e-56	214
rs:WP_003427476	DNA topoisomerase III [Clostridium butyricum].	28.30	576	354	18	7	559	6	545	1e-56	214
rs:WP_016588639	DNA topoisomerase III, partial [Yersinia pestis].	27.71	545	359	13	7	531	4	533	1e-56	212
rs:WP_028393890	DNA topoisomerase III [Bacillus sp. FJAT-14515].	29.97	584	351	21	3	559	2	554	1e-56	214
rs:WP_020827202	DNA topoisomerase III [Serratia liquefaciens].	27.71	545	359	13	7	531	4	533	2e-56	213
rs:WP_016792776	DNA topoisomerase III [Vibrio cyclitrophicus].	28.80	566	364	15	7	548	5	555	2e-56	213
rs:WP_042545975	DNA topoisomerase III [Yersinia aldovae].	27.89	545	358	13	7	531	4	533	2e-56	213
rs:WP_022160958	DNA topoisomerase III [Odoribacter splanchnicus CAG:14].	30.30	538	326	19	8	531	5	507	2e-56	214
rs:WP_011816425	DNA topoisomerase III [Yersinia enterocolitica].	27.71	545	359	13	7	531	5	534	2e-56	213
tr:A0A0C7I149_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.73	565	323	17	5	548	4	515	2e-56	213
rs:WP_031942999	DNA processing protein [uncultured bacterium].	28.91	550	352	14	7	530	4	540	2e-56	213
rs:WP_024714484	DNA topoisomerase III [Bacillus tequilensis].	30.00	570	326	18	3	539	2	531	2e-56	214
rs:WP_011879513	DNA topoisomerase III [Desulfotomaculum reducens].	30.76	569	332	20	7	548	6	539	2e-56	214
rs:WP_038827751	DNA topoisomerase III [Bacillus subtilis].	30.00	570	326	18	3	539	2	531	2e-56	214
rs:WP_019823776	DNA topoisomerase III [Vibrio splendidus].	28.80	566	364	15	7	548	5	555	2e-56	213
rs:WP_002227932	DNA topoisomerase III [Yersinia pestis].	27.71	545	359	13	7	531	5	534	2e-56	213
rs:WP_045958510	DNA topoisomerase III [Xenorhabdus poinarii].	27.99	543	360	14	7	531	4	533	2e-56	213
rs:WP_017066255	DNA topoisomerase III [Vibrio crassostreae].	28.98	566	363	15	7	548	5	555	2e-56	213
rs:WP_002211670	DNA topoisomerase III [Yersinia pestis].	27.71	545	359	13	7	531	4	533	2e-56	213
rs:WP_024573010	DNA topoisomerase III [Bacillus subtilis].	30.09	575	328	19	3	544	2	535	2e-56	214
rs:WP_019079527	DNA topoisomerase III [Yersinia enterocolitica].	27.71	545	359	13	7	531	4	533	2e-56	213
rs:WP_040036331	DNA topoisomerase III [Bacillaceae bacterium MTCC 10057].	29.84	553	356	16	7	544	4	539	2e-56	213
rs:WP_020283118	DNA topoisomerase III [Yersinia enterocolitica].	27.71	545	359	13	7	531	5	534	2e-56	213
rs:WP_005166139	DNA topoisomerase III [Yersinia enterocolitica].	27.71	545	359	13	7	531	4	533	2e-56	212
rs:WP_026585960	DNA topoisomerase III [Bacillus sp. NSP9.1].	30.44	565	341	20	5	548	4	537	2e-56	214
rs:WP_038633249	MULTISPECIES: DNA topoisomerase III [Yersinia].	27.71	545	359	13	7	531	4	533	2e-56	212
rs:WP_013613151	DNA topoisomerase III [Odoribacter splanchnicus].	30.30	538	326	19	8	531	5	507	2e-56	213
rs:WP_031787084	DNA topoisomerase III [Staphylococcus aureus].	28.76	619	387	20	7	606	5	588	2e-56	213
rs:WP_010437081	DNA topoisomerase III [Vibrio cyclitrophicus].	28.80	566	364	15	7	548	5	555	2e-56	213
rs:WP_024721442	DNA topoisomerase III [Clostridiales bacterium VE202-01].	30.03	576	350	20	5	559	4	547	2e-56	214
rs:WP_039062795	DNA topoisomerase III [Bacillus amyloliquefaciens].	29.72	572	325	19	3	539	2	531	2e-56	214
rs:WP_012819086	DNA topoisomerase III [Paenibacillus sp. Y412MC10].	29.35	627	362	19	7	602	5	581	2e-56	213
gpu:CP009997_560	DNA topoisomerase III family protein [Yersinia kristensenii]	27.71	545	359	13	7	531	5	534	2e-56	212
rs:WP_039315510	DNA topoisomerase III [Clostridium baratii].	29.97	574	350	20	7	559	5	547	2e-56	213
rs:WP_015042714	MULTISPECIES: DNA topoisomerase III [Dehalobacter].	28.55	578	363	16	7	563	5	553	2e-56	213
rs:WP_032726499	DNA topoisomerase III [Bacillus subtilis].	30.00	570	326	18	3	539	2	531	2e-56	213
rs:WP_005540135	conjugal transfer protein TraE [Aggregatibacter actinomycetemcomitans].	28.08	577	372	11	7	557	4	563	2e-56	214
tr:W1U302_CLOBU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.30	576	354	18	7	559	33	572	2e-56	214
rs:WP_046050872	DNA topoisomerase III [Yersinia enterocolitica].	27.71	545	359	13	7	531	4	533	2e-56	212
rs:WP_031552787	DNA topoisomerase III [Gemella sanguinis].	30.18	560	327	18	5	546	3	516	2e-56	213
rs:WP_022584554	DNA topoisomerase III [Brevibacillus laterosporus].	29.13	563	350	17	7	548	6	540	2e-56	213
rs:WP_024486969	DNA topoisomerase III [Serratia fonticola].	27.71	545	359	13	7	531	4	533	2e-56	212
rs:WP_041175458	DNA topoisomerase III [Yersinia pseudotuberculosis].	27.71	545	359	13	7	531	4	533	2e-56	212
rs:WP_014662817	DNA topoisomerase III [Bacillus sp. JS].	30.00	570	326	18	3	539	2	531	2e-56	213
rs:WP_007781693	DNA topoisomerase III [Desulfosporosinus youngiae].	28.39	627	390	18	5	590	4	612	2e-56	214
rs:WP_016626025	DNA topoisomerase [Enterococcus faecalis].	28.96	594	359	17	5	563	3	568	2e-56	213
rs:WP_017085070	DNA topoisomerase III [Vibrio splendidus].	28.80	566	364	15	7	548	5	555	2e-56	213
rs:WP_032467116	DNA topoisomerase III [Yersinia pseudotuberculosis].	27.71	545	359	13	7	531	4	533	2e-56	212
rs:WP_021181214	DNA topoisomerase III [Serratia fonticola].	27.71	545	359	13	7	531	4	533	2e-56	212
rs:WP_035020436	DNA topoisomerase III [Carnobacterium sp. WN1374].	31.58	570	349	18	5	556	4	550	2e-56	213
rs:WP_033170946	DNA topoisomerase [Selenomonas sp. ND2010].	28.40	574	361	14	8	550	5	559	2e-56	214
rs:WP_012105118	DNA topoisomerase III [Yersinia pseudotuberculosis].	27.71	545	359	13	7	531	4	533	2e-56	212
gp:CP000950_2060	DNA topoisomerase III [Yersinia pseudotuberculosis YPIII]	27.71	545	359	13	7	531	5	534	2e-56	212
tr:Q66AN9_YERPS	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953}; Flags: Precursor;	27.71	545	359	13	7	531	5	534	2e-56	212
tr:A0A0C7LFG7_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.73	565	323	17	5	548	4	515	2e-56	213
rs:WP_017070329	DNA topoisomerase III [Vibrio crassostreae].	28.98	566	363	15	7	548	5	555	2e-56	213
rs:WP_025848350	DNA topoisomerase III [Brevibacillus agri].	30.28	568	346	20	3	548	2	541	2e-56	213
tr:W0UKE1_YEREN	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.71	545	359	13	7	531	5	534	2e-56	212
rs:WP_025205685	DNA topoisomerase III [Dehalobacter restrictus].	28.37	578	364	16	7	563	5	553	2e-56	213
rs:WP_019225406	DNA topoisomerase III [Dehalobacter sp. E1].	28.37	578	364	16	7	563	5	553	2e-56	213
rs:WP_033848526	MULTISPECIES: DNA topoisomerase III [Yersinia].	27.71	545	359	13	7	531	4	533	2e-56	212
tr:A0A077V8F9_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.76	619	387	20	7	606	5	588	2e-56	213
rs:WP_017251542	DNA topoisomerase III [Brevibacillus brevis].	30.63	568	340	21	3	546	2	539	2e-56	213
rs:WP_022249592	DNA topoisomerase III [Eubacterium sp. CAG:274].	30.23	559	347	17	7	550	5	535	2e-56	213
rs:WP_031545111	DNA topoisomerase III [Salinicoccus luteus].	28.83	562	356	13	5	549	4	538	2e-56	213
rs:WP_003366191	DNA topoisomerase III [Clostridium botulinum].	29.53	569	340	20	8	532	7	558	2e-56	214
rs:WP_019162292	DNA topoisomerase III [Ruminococcus sp. JC304].	29.23	561	327	18	7	532	5	530	2e-56	213
tr:F3J716_PSEAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.86	566	353	13	7	541	4	556	2e-56	213
tr:C6HTV9_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.15	549	346	19	8	539	5	538	2e-56	213
rs:WP_002383601	DNA topoisomerase III, partial [Yersinia pestis].	27.56	537	362	12	7	527	4	529	3e-56	210
rs:WP_010894513	DNA topoisomerase [Xylella fastidiosa].	28.83	555	345	14	8	530	5	541	3e-56	213
rs:WP_035127158	DNA topoisomerase III, partial [Conexibacter woesei].	27.72	570	370	15	7	550	6	559	3e-56	213
rs:WP_035066549	DNA topoisomerase III [Anoxybacillus gonensis].	29.66	553	325	20	7	546	5	506	3e-56	213
rs:WP_017063444	DNA topoisomerase III [Vibrio crassostreae].	28.98	566	363	15	7	548	5	555	3e-56	212
rs:WP_034165111	DNA topoisomerase III [Edwardsiella tarda].	28.19	564	364	16	7	548	4	548	3e-56	212
rs:WP_004945367	DNA topoisomerase III [Serratia plymuthica].	28.07	545	357	13	7	531	4	533	3e-56	212
rs:WP_017161576	hypothetical protein [Xanthomonas axonopodis].	27.77	569	365	16	7	548	4	553	3e-56	213
rs:WP_003234388	DNA topoisomerase III [Bacillus subtilis].	30.00	570	326	18	3	539	2	531	3e-56	213
rs:WP_041850711	DNA topoisomerase III [Bacillus subtilis].	30.00	570	326	18	3	539	2	531	3e-56	213
rs:WP_032076274	DNA topoisomerase III [Clostridium drakei].	27.76	616	375	19	7	590	6	583	3e-56	213
rs:WP_011304091	DNA topoisomerase III [Sphingomonas sp. A1].	28.91	550	352	14	7	530	4	540	3e-56	213
rs:WP_024614465	DNA topoisomerase III [Clostridium sp. Ade.TY].	29.53	579	358	19	1	559	1	549	3e-56	213
rs:WP_034143173	DNA topoisomerase III [Desulfosporosinus sp. BICA1-9].	28.27	573	351	16	5	550	4	543	3e-56	213
rs:WP_037419974	DNA topoisomerase III, partial [Serratia grimesii].	27.54	541	365	12	7	531	4	533	3e-56	212
rs:WP_000766776	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.43	539	343	18	7	530	4	525	3e-56	213
rs:WP_044384737	DNA topoisomerase III [Marinobacter excellens].	28.91	543	357	12	8	530	5	538	3e-56	213
rs:WP_045726250	DNA topoisomerase III [Clostridium baratii].	29.62	574	352	20	7	559	5	547	3e-56	213
rs:WP_033843881	DNA topoisomerase III [Geobacillus subterraneus].	28.98	559	324	17	7	546	5	509	3e-56	213
rs:WP_013726277	DNA topoisomerase III [Clostridium botulinum].	30.30	571	343	18	1	548	1	539	3e-56	213
rs:WP_044702341	DNA topoisomerase III, partial [Escherichia coli].	28.60	521	345	13	8	512	5	514	3e-56	209
rs:WP_017059374	DNA topoisomerase III [Vibrio crassostreae].	28.80	566	364	15	7	548	5	555	3e-56	212
rs:WP_025844431	DNA topoisomerase III [Paenibacillus ehimensis].	31.55	580	323	20	7	555	5	541	3e-56	213
rs:WP_047182112	DNA topoisomerase III [Bacillus subtilis].	30.09	575	328	19	3	544	2	535	3e-56	213
tr:W7ZP94_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.91	555	349	17	7	548	6	533	3e-56	213
rs:WP_041336817	DNA topoisomerase III [Bacillus subtilis].	30.09	575	328	19	3	544	2	535	3e-56	213
rs:WP_003144959	DNA topoisomerase III [Gemella haemolysans].	30.00	570	327	17	5	548	3	526	3e-56	213
rs:WP_015613674	DNA topoisomerase III [Clostridium pasteurianum].	29.72	572	345	20	1	548	1	539	3e-56	213
rs:WP_003225098	DNA topoisomerase III [Bacillus subtilis].	30.00	570	326	18	3	539	2	531	3e-56	213
rs:WP_026478513	DNA topoisomerase III [Alkaliphilus transvaalensis].	29.71	579	350	21	7	559	6	553	3e-56	213
rs:WP_042977129	DNA topoisomerase III [Bacillus subtilis].	30.00	570	326	18	3	539	2	531	3e-56	213
rs:WP_003465183	DNA topoisomerase III [Gracilibacillus halophilus].	29.43	547	341	18	3	532	2	520	3e-56	213
rs:WP_013488617	DNA topoisomerase III [Bacillus cellulosilyticus].	28.98	597	381	18	7	580	4	580	3e-56	213
rs:WP_016798141	DNA topoisomerase III [Vibrio cyclitrophicus].	28.62	566	365	15	7	548	5	555	3e-56	212
tr:A0A0A8VWD1_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.73	565	323	17	5	548	4	515	3e-56	213
rs:WP_032101858	DNA topoisomerase III, partial [Anoxybacillus flavithermus].	29.46	560	317	19	7	546	5	506	3e-56	213
rs:WP_038704788	DNA topoisomerase III [Planococcus sp. PAMC 21323].	30.57	566	339	21	1	548	1	530	3e-56	213
rs:WP_039220949	DNA topoisomerase III [Clostridium novyi].	29.95	571	345	18	1	548	1	539	3e-56	213
rs:WP_002541082	DNA topoisomerase III [Grimontia indica].	29.08	564	361	16	7	549	5	550	3e-56	212
tr:A0A0C7J747_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.73	565	323	17	5	548	4	515	3e-56	213
rs:WP_024528781	DNA topoisomerase III [Serratia fonticola].	27.71	545	359	13	7	531	4	533	4e-56	211
tr:A0A0C7RVR1_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.73	565	323	17	5	548	4	515	4e-56	213
rs:WP_003339104	DNA topoisomerase III [Brevibacillus laterosporus].	29.43	564	347	19	7	548	6	540	4e-56	213
rs:WP_017209631	DNA topoisomerase III [Clostridium beijerinckii].	29.36	579	357	19	3	559	2	550	4e-56	213
rs:WP_028022843	DNA topoisomerase III [Enterovibrio calviensis].	28.83	562	365	15	7	549	5	550	4e-56	211
rs:WP_042987872	DNA topoisomerase III [Vibrio cholerae].	30.16	547	349	14	8	532	5	540	4e-56	213
rs:WP_017092500	DNA topoisomerase III [Vibrio splendidus].	28.80	566	364	15	7	548	5	555	4e-56	212
rs:WP_035188903	DNA topoisomerase III [Bacillus coagulans].	29.85	546	345	18	3	530	2	527	4e-56	213
rs:WP_006835528	DNA topoisomerase III [Bacillus sp. SG-1].	29.23	544	349	15	4	530	1	525	4e-56	213
rs:WP_003513145	DNA topoisomerase III [Ruminiclostridium thermocellum].	29.36	596	356	19	8	557	7	583	4e-56	212
rs:WP_040441619	hypothetical protein, partial [Alicyclobacillus acidoterrestris].	29.96	554	346	16	7	543	4	532	4e-56	212
tr:A0A0C7HMD1_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.73	565	323	17	5	548	4	515	4e-56	213
rs:WP_021130050	DNA topoisomerase III family protein [[Clostridium] sordellii].	29.73	565	323	17	5	548	4	515	4e-56	213
rs:WP_029452668	DNA topoisomerase III [Clostridium algidicarnis].	29.03	620	382	21	3	599	2	586	4e-56	213
rs:WP_029317313	DNA topoisomerase 3 [Bacillus subtilis].	30.00	570	326	18	3	539	2	531	4e-56	213
sp:TOP3_BACSU	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	30.00	570	326	18	3	539	2	531	4e-56	213
rs:WP_016627352	DNA topoisomerase [Enterococcus faecalis].	28.79	594	360	17	5	563	3	568	4e-56	213
rs:WP_027409388	DNA topoisomerase III [Anoxybacillus tepidamans].	30.88	557	317	22	7	546	5	510	4e-56	212
rs:WP_016359545	DNA topoisomerase III [Gemella sanguinis].	30.05	559	329	16	5	546	3	516	4e-56	212
rs:WP_014478870	DNA topoisomerase III [Bacillus subtilis].	30.18	570	325	18	3	539	2	531	4e-56	213
rs:WP_045643222	DNA topoisomerase III [Peptococcaceae bacterium BRH_c8a].	30.33	577	347	21	7	559	8	553	4e-56	213
rs:WP_017084055	DNA topoisomerase III [Vibrio splendidus].	28.80	566	364	15	7	548	5	555	4e-56	212
rs:WP_017111130	DNA topoisomerase III [Vibrio tasmaniensis].	28.80	566	364	15	7	548	5	555	4e-56	212
rs:WP_031943207	TraE DNA topoisomerase [uncultured bacterium].	29.09	550	350	13	7	530	4	539	4e-56	213
rs:WP_020189016	DNA topoisomerase III [Kurthia sp. Dielmo].	30.20	553	334	19	7	539	6	526	4e-56	213
rs:WP_022211736	DNA topoisomerase III [Clostridium sp. CAG:265].	29.12	594	342	20	1	559	1	550	4e-56	213
tr:A0A0C7IWU1_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.73	565	323	17	5	548	4	515	4e-56	212
rs:WP_042385891	DNA topoisomerase III [Geobacillus thermoglucosidasius].	29.16	559	360	15	4	544	1	541	4e-56	212
rs:WP_003335207	DNA topoisomerase III [Brevibacillus laterosporus].	29.43	564	347	19	7	548	6	540	4e-56	213
rs:WP_014098418	DNA topoisomerase III [Bacillus coagulans].	29.67	546	346	18	3	530	2	527	4e-56	213
tr:A0A0C7SIW7_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.73	565	323	17	5	548	4	515	4e-56	212
rs:WP_025025884	DNA topoisomerase III [Bacillus mannanilyticus].	31.47	518	323	16	34	539	52	549	4e-56	213
rs:WP_046160064	DNA topoisomerase III [Bacillus sp. CMAA 1185].	30.09	575	328	19	3	544	2	535	4e-56	213
rs:WP_015364790	DNA topoisomerase III [Staphylococcus warneri].	28.88	599	377	18	7	590	5	569	4e-56	212
tr:A0A078BHB1_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.69	586	362	18	3	567	56	612	5e-56	213
rs:WP_004734086	DNA topoisomerase III [Vibrio splendidus].	28.80	566	364	15	7	548	5	555	5e-56	212
rs:WP_004444211	DNA topoisomerase III [Clostridium botulinum].	29.95	571	345	18	1	548	1	539	5e-56	213
tr:A0A0C7SIK7_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.73	565	323	17	5	548	4	515	5e-56	212
rs:WP_022444575	DNA topoisomerase [Sutterella sp. CAG:351].	29.54	589	363	23	7	568	6	569	5e-56	213
rs:WP_021875939	DNA topoisomerase [Clostridium chauvoei].	30.03	576	349	21	7	559	6	550	5e-56	213
rs:WP_002609188	DNA topoisomerase III [[Clostridium] innocuum].	27.26	576	372	16	3	559	2	549	5e-56	213
rs:WP_011969196	DNA topoisomerase III [Clostridium beijerinckii].	29.19	579	358	19	3	559	2	550	5e-56	213
rs:WP_034301545	DNA topoisomerase III [Bacillus sp. FJAT-14515].	29.80	557	352	16	7	544	3	539	5e-56	212
rs:WP_004740668	DNA topoisomerase III [Vibrio splendidus].	29.03	565	364	15	7	548	5	555	5e-56	211
rs:WP_044161796	DNA topoisomerase III [Salinibacillus aidingensis].	30.00	570	326	18	3	539	2	531	5e-56	213
tr:T0BQW9_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.96	554	346	16	7	543	4	532	5e-56	212
rs:WP_028408630	DNA topoisomerase III [Bacillus sp. 171095_106].	29.25	547	331	14	7	544	5	504	5e-56	212
rs:WP_003440585	DNA topoisomerase III [Clostridium pasteurianum].	29.58	568	344	19	5	548	4	539	5e-56	212
rs:WP_043858106	DNA topoisomerase III [Bacillus subtilis].	30.00	570	326	18	3	539	2	531	5e-56	212
rs:WP_025568346	DNA topoisomerase III [Bacillus sp. JGI 001005-J19].	28.89	637	380	22	3	606	2	598	5e-56	212
rs:WP_041351795	DNA topoisomerase III [Bacillus subtilis].	30.00	570	326	18	3	539	2	531	5e-56	212
rs:WP_034367860	hypothetical protein, partial [Comamonas testosteroni].	29.20	572	361	16	8	552	5	559	6e-56	212
rs:WP_024371561	DNA topoisomerase III [Exiguobacterium sp. 8-11-1].	30.30	538	341	16	7	530	4	521	6e-56	212
rs:WP_007721869	MULTISPECIES: DNA topoisomerase III [Carnobacterium].	30.95	559	346	17	7	548	5	540	6e-56	212
rs:WP_015252793	DNA Topoisomerase III [Bacillus subtilis].	30.00	570	326	18	3	539	2	531	6e-56	212
rs:WP_008496825	DNA topoisomerase III [Planococcus halocryophilus].	30.97	565	338	21	1	548	1	530	6e-56	212
tr:A0A0C7GXA1_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.56	565	324	17	5	548	4	515	6e-56	212
rs:WP_017794555	hypothetical protein [Streptococcus iniae].	31.24	589	346	22	5	563	3	562	6e-56	212
rs:WP_009848706	DNA topoisomerase III [Vibrio sp. MED222].	28.85	565	365	15	7	548	5	555	6e-56	211
rs:WP_045383398	DNA topoisomerase III [Bacillus subtilis].	30.49	574	318	21	3	539	2	531	6e-56	212
rs:WP_019257504	DNA topoisomerase III [Bacillus subtilis].	29.82	570	327	18	3	539	2	531	6e-56	212
rs:WP_026858958	DNA topoisomerase III [Jeotgalicoccus psychrophilus].	30.88	570	342	21	7	559	6	540	6e-56	212
tr:A0A0C7RF12_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.56	565	324	17	5	548	4	515	6e-56	212
rs:WP_046222677	DNA topoisomerase III [Vibrio sp. ECSMB14106].	28.80	566	364	15	7	548	5	555	6e-56	211
rs:WP_009245073	DNA topoisomerase III [Lachnospiraceae bacterium 2_1_58FAA].	28.93	560	341	17	7	539	5	534	6e-56	212
rs:WP_044337013	DNA topoisomerase III [Bacillus aquimaris].	27.90	595	392	15	4	580	1	576	6e-56	212
rs:WP_046010027	DNA topoisomerase III [Oleispira antarctica].	26.86	633	399	20	8	593	5	620	6e-56	211
rs:WP_008727758	DNA topoisomerase III [Erysipelotrichaceae bacterium 2_2_44A].	27.26	576	372	16	3	559	2	549	6e-56	212
rs:WP_025670986	DNA topoisomerase III [Bacillus sp. JGI 001011-F15].	28.89	637	380	22	3	606	2	598	6e-56	212
rs:WP_035185002	DNA topoisomerase III [Bacillus coagulans].	29.66	553	337	16	3	530	2	527	6e-56	212
rs:WP_017079516	DNA topoisomerase III [Vibrio splendidus].	28.62	566	365	15	7	548	5	555	6e-56	211
rs:WP_029093488	DNA topoisomerase III [Budvicia aquatica].	27.87	567	368	16	8	552	5	552	6e-56	211
rs:WP_002844059	DNA topoisomerase [Peptostreptococcus anaerobius].	30.03	596	379	17	7	590	4	573	6e-56	212
rs:WP_007728127	DNA topoisomerase III [Brevibacillus sp. BC25].	30.47	571	341	21	3	548	2	541	6e-56	212
rs:WP_041904784	DNA topoisomerase III [Bacillus sp. BSC154].	30.00	570	326	18	3	539	2	531	6e-56	212
rs:WP_032099574	DNA topoisomerase III [Anoxybacillus flavithermus].	27.39	617	402	19	7	603	4	594	7e-56	212
rs:WP_034265868	DNA topoisomerase III [Bacillus sp. Aph1].	29.43	547	330	14	7	544	5	504	7e-56	212
rs:WP_034582630	DNA topoisomerase III [Clostridium acetobutylicum].	29.53	623	374	22	7	603	6	589	7e-56	212
rs:WP_015042715	MULTISPECIES: DNA topoisomerase III [Dehalobacter].	27.89	588	358	19	7	550	6	571	7e-56	213
rs:WP_039260585	DNA topoisomerase III [Clostridium tetani].	28.32	579	362	19	5	559	4	553	7e-56	212
rs:WP_007287723	DNA topoisomerase III [Intestinibacter bartlettii].	30.18	550	330	16	7	544	6	513	7e-56	212
rs:WP_046417497	DNA topoisomerase [Xylella fastidiosa].	28.65	555	346	14	8	530	5	541	7e-56	211
tr:F7ML35_CLOBO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.95	571	345	18	1	548	1	539	7e-56	212
gp:CP006955_1251	DNA topoisomerase 3 [Bibersteinia trehalosi USDA-ARS-USMARC-189]	28.54	529	333	14	94	602	25	528	7e-56	209
rs:WP_010966230	DNA topoisomerase III [Clostridium acetobutylicum].	29.53	623	374	22	7	603	6	589	7e-56	212
rs:WP_017095039	DNA topoisomerase III [Vibrio splendidus].	28.62	566	365	15	7	548	5	555	7e-56	211
rs:WP_028413452	DNA topoisomerase III [Bacillus sp. 278922_107].	29.43	547	330	14	7	544	5	504	7e-56	211
rs:WP_011098708	DNA topoisomerase III [Clostridium tetani].	28.40	581	359	19	5	559	4	553	7e-56	212
rs:WP_015392895	DNA topoisomerase 3 [Clostridium saccharoperbutylacetonicum].	28.37	578	364	17	3	559	2	550	7e-56	212
rs:WP_031516833	DNA topoisomerase III [Desulfotomaculum alkaliphilum].	30.31	584	351	17	5	559	3	559	7e-56	213
tr:A0A084YU57_9ENTR	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.54	541	365	12	7	531	4	533	7e-56	212
rs:WP_012603511	DNA topoisomerase III [Vibrio tasmaniensis].	28.80	566	364	15	7	548	5	555	7e-56	211
rs:WP_014112696	DNA topoisomerase III [Bacillus subtilis].	30.00	570	326	18	3	539	2	531	7e-56	212
gp:CP007439_2807	DNA topoisomerase III [Serratia plymuthica]	27.91	541	363	12	7	531	4	533	7e-56	211
rs:WP_004841232	DNA topoisomerase III [[Ruminococcus] gnavus].	29.11	553	335	17	7	532	5	527	7e-56	212
rs:WP_013489388	DNA topoisomerase III [Bacillus cellulosilyticus].	28.11	555	355	14	5	539	4	534	8e-56	212
rs:WP_005344509	DNA topoisomerase III [[Eubacterium] hallii].	27.17	552	361	13	7	544	5	529	8e-56	212
tr:A0A0A8VKA8_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.73	565	323	17	5	548	4	515	8e-56	211
tr:A0A0C7I9V3_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.68	556	319	16	5	539	4	508	8e-56	211
rs:WP_014460219	DNA topoisomerase III [Bacillus megaterium].	29.25	547	331	14	7	544	5	504	8e-56	211
rs:WP_023466257	DNA topoisomerase [Lactobacillus fermentum].	30.57	592	352	20	5	563	3	568	8e-56	212
tr:B3DUF7_METI4	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.21	566	352	19	5	548	4	548	8e-56	213
rs:WP_017107363	DNA topoisomerase III [Vibrio tasmaniensis].	28.80	566	364	15	7	548	5	555	8e-56	211
rs:WP_014475847	DNA topoisomerase III [Bacillus subtilis].	30.00	570	326	18	3	539	2	531	8e-56	212
rs:WP_022169972	DNA topoisomerase [Eubacterium hallii CAG:12].	27.17	552	361	13	7	544	5	529	8e-56	212
rs:WP_034394054	hypothetical protein, partial [Comamonas testosteroni].	29.20	572	361	16	8	552	5	559	9e-56	212
rs:WP_017072510	DNA topoisomerase III [Vibrio splendidus].	28.80	566	364	15	7	548	5	555	9e-56	211
tr:A0A077VCU2_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.59	619	388	20	7	606	5	588	9e-56	211
rs:WP_002230887	DNA topoisomerase III [Yersinia pestis].	27.71	545	359	13	7	531	4	533	9e-56	211
tr:A0A096FM68_COMTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.20	572	361	16	8	552	5	559	9e-56	212
rs:WP_042410060	DNA topoisomerase III [Geobacillus caldoxylosilyticus].	28.73	557	365	14	4	544	1	541	9e-56	211
rs:WP_044051694	DNA topoisomerase, partial [Enterococcus faecium].	29.50	583	369	18	5	563	3	567	9e-56	210
rs:WP_041726130	hypothetical protein [Caldisericum exile].	29.95	581	354	20	5	568	4	548	9e-56	212
rs:WP_004091429	DNA topoisomerase [Xylella fastidiosa].	28.65	555	346	14	8	530	5	541	9e-56	211
rs:WP_046402305	DNA topoisomerase III [Odoribacter sp. UNK.MGS-12].	30.11	538	327	19	8	531	5	507	9e-56	211
rs:WP_028406384	DNA topoisomerase III [Bacillus sp. J13].	28.98	628	365	20	7	603	5	582	1e-55	211
rs:WP_022038466	MULTISPECIES: DNA topoisomerase [Clostridiales].	29.48	553	333	18	7	532	5	527	1e-55	211
rs:WP_004086664	DNA topoisomerase [Xylella fastidiosa].	28.65	555	346	15	8	530	5	541	1e-55	211
rs:WP_014748829	DNA topoisomerase [Enterococcus faecium].	29.50	583	369	18	5	563	3	567	1e-55	210
gp:AE017042_1901	DNA topoisomerase III [Yersinia pestis biovar Microtus str. 91001]	27.71	545	359	13	7	531	5	534	1e-55	210
rs:WP_039235853	DNA topoisomerase III [Clostridium sp. K25].	29.95	571	345	18	1	548	1	539	1e-55	211
tr:A0A0E3BV48_COMTE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGH12677.1};	29.20	572	361	16	8	552	5	559	1e-55	212
rs:WP_022343863	DNA topoisomerase [Clostridium sp. CAG:356].	28.57	574	348	16	7	532	6	565	1e-55	210
rs:WP_031841774	hypothetical protein [Vibrio parahaemolyticus].	33.42	389	243	9	7	386	5	386	1e-55	205
tr:A0A077U5P0_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.43	619	389	20	7	606	5	588	1e-55	211
rs:WP_033578902	DNA topoisomerase III [Bacillus aryabhattai].	29.43	547	330	14	7	544	5	504	1e-55	211
rs:WP_008817173	DNA topoisomerase III [Peptoclostridium difficile].	27.35	574	374	15	3	559	2	549	1e-55	211
rs:WP_029321603	DNA topoisomerase III [Bacillus sp. RP1137].	29.10	543	337	13	7	544	5	504	1e-55	211
tr:A0A077U2I5_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.43	619	389	20	7	606	5	588	1e-55	211
rs:WP_016764011	DNA topoisomerase III [Bacillus megaterium].	29.25	547	331	14	7	544	5	504	1e-55	211
rs:WP_009247719	MULTISPECIES: DNA topoisomerase III [Lachnospiraceae].	29.49	546	336	16	7	532	5	521	1e-55	211
rs:WP_044907297	DNA topoisomerase III [[Clostridium] innocuum].	27.26	576	372	15	3	559	2	549	1e-55	211
rs:WP_040942445	DNA topoisomerase III [Xanthomonas campestris].	27.54	581	384	16	43	603	23	586	1e-55	211
rs:WP_026683476	DNA topoisomerase III [Bacillus coagulans].	29.66	553	337	16	3	530	2	527	1e-55	211
tr:I0GKW5_CALEA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.95	581	354	20	5	568	3	547	1e-55	212
rs:WP_035111043	DNA topoisomerase III [Clostridium tetani].	28.40	581	359	19	5	559	4	553	1e-55	211
rs:WP_021737651	DNA topoisomerase [Eubacterium ramulus].	27.42	558	352	15	5	539	4	531	1e-55	211
tr:A0A0C7NXC2_CLOSO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.64	560	330	17	5	548	4	515	1e-55	211
rs:WP_015715259	DNA topoisomerase III [Bacillus subtilis].	30.00	570	326	18	3	539	2	531	1e-55	211
rs:WP_003019459	DNA topoisomerase III [Blautia hansenii].	29.49	546	336	16	7	532	5	521	1e-55	211
rs:WP_010649676	DNA topoisomerase [Oceanobacillus massiliensis].	28.78	608	387	20	7	590	4	589	1e-55	211
rs:WP_012260746	DNA topoisomerase III [Bacillus weihenstephanensis].	30.43	539	343	19	7	530	4	525	1e-55	211
rs:WP_025481008	DNA topoisomerase [Enterococcus faecium].	30.02	583	366	18	5	563	3	567	1e-55	211
rs:WP_018086956	hypothetical protein [Desulfurispora thermophila].	29.78	581	350	21	5	559	4	552	1e-55	211
rs:WP_043982332	DNA topoisomerase III [Bacillus aryabhattai].	29.25	547	331	14	7	544	5	504	1e-55	211
rs:WP_027724303	DNA topoisomerase III [Tuberibacillus calidus].	29.42	554	329	18	7	546	5	510	1e-55	211
tr:F7NDM8_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.40	568	342	17	3	539	2	541	1e-55	211
rs:WP_047130864	DNA topoisomerase III [Staphylococcus condimenti].	28.37	564	363	16	7	559	5	538	1e-55	211
rs:WP_019533711	DNA topoisomerase III [Paenibacillus ginsengihumi].	29.95	571	324	17	7	544	5	532	1e-55	211
rs:WP_022300665	DNA topoisomerase [Erysipelotrichaceae bacterium CAG:64].	27.26	576	372	16	3	559	2	549	1e-55	211
rs:WP_009587401	DNA topoisomerase III [Clostridium sp. HGF2].	27.35	574	374	15	3	559	2	549	1e-55	211
rs:WP_028386518	DNA topoisomerase [Legionella geestiana].	29.30	546	358	13	8	539	5	536	1e-55	210
rs:WP_022118909	DNA topoisomerase III [Firmicutes bacterium CAG:56].	27.82	593	371	18	8	554	6	587	1e-55	211
rs:WP_019595521	MULTISPECIES: DNA topoisomerase [Peptostreptococcus].	30.03	596	379	17	7	590	4	573	1e-55	211
rs:WP_041339607	DNA topoisomerase III [Bacillus subtilis].	30.00	570	326	18	3	539	2	531	1e-55	211
rs:WP_023437240	DNA topoisomerase III [Clostridium tetani].	28.13	583	366	19	1	559	1	554	1e-55	211
rs:WP_017033131	DNA topoisomerase III [Vibrio genomosp. F10].	28.40	574	356	15	7	548	5	555	1e-55	210
rs:WP_008357118	DNA topoisomerase III [Bacillus xiamenensis].	29.68	566	348	17	3	548	2	537	1e-55	211
rs:WP_002845103	DNA topoisomerase [Peptostreptococcus anaerobius].	30.03	596	379	17	7	590	4	573	1e-55	211
rs:WP_032121230	DNA topoisomerase III [Clostridium sp. LF2].	28.62	629	384	22	1	603	1	590	1e-55	211
rs:WP_006208277	DNA topoisomerase III [Paenibacillus vortex].	29.39	626	362	20	7	602	5	580	1e-55	211
rs:WP_037994261	DNA topoisomerase III [Thermoactinomyces sp. Gus2-1].	29.62	557	347	17	5	548	4	528	1e-55	211
rs:WP_010287202	DNA topoisomerase III [Kurthia massiliensis].	29.69	549	342	19	7	539	6	526	1e-55	211
rs:WP_021752614	DNA topoisomerase III [Gemella bergeri].	30.32	564	321	20	5	546	3	516	1e-55	211
tr:W8UIN6_YEREN	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.71	545	359	13	7	531	4	533	1e-55	210
rs:WP_018403339	DNA topoisomerase III [Marinobacter lipolyticus].	29.10	567	371	15	8	552	5	562	1e-55	211
rs:WP_010333072	DNA topoisomerase III [Bacillus mojavensis].	29.82	570	327	18	3	539	2	531	1e-55	211
rs:WP_009433703	DNA topoisomerase III [Porphyromonas sp. oral taxon 279].	28.82	569	348	19	7	546	2	542	2e-55	210
rs:WP_019713359	DNA topoisomerase III [Bacillus subtilis].	30.07	572	326	19	1	539	1	531	2e-55	211
rs:WP_021620679	DNA topoisomerase [Aneurinibacillus aneurinilyticus].	30.30	505	316	13	43	530	42	527	2e-55	211
tr:C4S6E6_YERBE	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.71	545	359	14	7	531	5	534	2e-55	210
rs:WP_000214012	DNA topoisomerase III [Staphylococcus aureus].	30.51	554	351	16	3	544	2	533	2e-55	211
rs:WP_013083050	DNA topoisomerase III [Bacillus megaterium].	29.25	547	331	14	7	544	5	504	2e-55	211
gpu:CP007165_390	DNA topoisomerase III [Bacillus amyloliquefaciens subsp. plantarum NJN6]	30.07	572	323	19	3	539	10	539	2e-55	211
rs:WP_017080912	DNA topoisomerase III [Vibrio splendidus].	28.62	566	365	15	7	548	5	555	2e-55	210
rs:WP_024084897	DNA topoisomerase III [Bacillus amyloliquefaciens].	30.07	572	323	19	3	539	2	531	2e-55	211
rs:WP_046059419	DNA topoisomerase III [Clostridium sp. IBUN22A].	28.30	576	354	18	7	559	6	545	2e-55	211
rs:WP_046057448	DNA topoisomerase III [Clostridium sp. IBUN62F].	28.12	576	355	18	7	559	6	545	2e-55	211
rs:WP_019225407	MULTISPECIES: DNA topoisomerase III [Dehalobacter].	27.26	587	363	17	7	550	6	571	2e-55	211
rs:WP_017466745	DNA topoisomerase III [Staphylococcus aureus].	28.70	568	357	18	7	559	5	539	2e-55	211
rs:WP_013823470	DNA topoisomerase III [Desulfotomaculum kuznetsovii].	30.40	579	351	19	7	559	5	557	2e-55	211
rs:WP_014022468	DNA topoisomerase III [Cyclobacterium marinum].	30.12	561	346	18	8	557	5	530	2e-55	211
rs:WP_038427393	DNA topoisomerase 3 [Bacillus subtilis].	29.82	570	327	18	3	539	2	531	2e-55	211
rs:WP_024853195	DNA topoisomerase III [[Ruminococcus] gnavus].	28.77	563	347	16	7	544	5	538	2e-55	211
rs:WP_045290378	DNA topoisomerase III [Bacillus aryabhattai].	29.07	547	332	14	7	544	5	504	2e-55	210
rs:WP_038242886	DNA topoisomerase III [Virgibacillus sp. Vm-5].	30.67	551	342	16	1	536	1	526	2e-55	211
rs:WP_021289198	DNA topoisomerase III [Virgibacillus sp. CM-4].	30.67	551	342	16	1	536	1	526	2e-55	211
rs:WP_027631371	DNA topoisomerase III [Clostridium hydrogeniformans].	28.10	573	365	16	7	559	6	551	2e-55	211
rs:WP_032899009	DNA topoisomerase III [Yersinia bercovieri].	27.71	545	359	14	7	531	4	533	2e-55	209
tr:C4T5R3_YERIN	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.34	545	361	13	7	531	5	534	2e-55	209
rs:WP_038283351	DNA topoisomerase III [[Clostridium] celerecrescens].	29.20	565	348	16	7	548	5	540	2e-55	211
rs:WP_032907590	DNA topoisomerase III [Yersinia intermedia].	27.34	545	361	13	7	531	4	533	2e-55	209
tr:A0A077UAU7_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.76	619	387	20	7	606	5	588	2e-55	211
tr:C4SCV1_YERMO	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.52	545	360	14	7	531	5	534	2e-55	209
rs:WP_034037945	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	33.50	403	237	11	170	552	14	405	2e-55	207
tr:R2PQJ8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.85	583	367	18	5	563	4	568	2e-55	211
tr:F4BPK6_CARS1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.40	570	350	18	5	556	8	554	2e-55	211
rs:WP_046524222	DNA topoisomerase III [Bacillus sp. SA2-6].	28.37	557	359	15	7	544	4	539	2e-55	211
rs:WP_045923569	DNA topoisomerase III [Clostridium tetani].	28.15	579	363	19	5	559	4	553	2e-55	211
rs:WP_031892018	DNA topoisomerase III, partial [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	2e-55	208
rs:WP_004437152	DNA topoisomerase III [Bacillus methanolicus].	29.85	546	342	17	7	530	4	530	2e-55	211
rs:WP_038585649	DNA topoisomerase III [Paenibacillus sp. FSL H7-0357].	29.75	568	329	19	7	550	5	526	2e-55	210
rs:WP_027419728	DNA topoisomerase III [Crocinitomix catalasitica].	30.09	535	331	16	8	531	5	507	2e-55	210
rs:WP_032814471	DNA topoisomerase III [Yersinia mollaretii].	27.52	545	360	14	7	531	4	533	2e-55	209
rs:WP_003240282	DNA topoisomerase III [Bacillus subtilis].	29.65	570	328	18	3	539	2	531	2e-55	211
rs:WP_029541017	DNA topoisomerase [Selenomonas ruminantium].	29.84	563	337	17	8	532	5	547	2e-55	211
rs:WP_042957003	DNA topoisomerase [Enterococcus faecium].	29.85	583	367	18	5	563	3	567	2e-55	211
rs:WP_034104804	DNA topoisomerase III [Desulfotomaculum sp. BICA1-6].	30.91	550	338	18	7	539	8	532	2e-55	211
rs:WP_039255204	DNA topoisomerase III [Clostridium novyi].	29.17	569	342	20	8	532	7	558	2e-55	211
rs:WP_046177003	DNA topoisomerase [Streptococcus dysgalactiae].	29.52	542	329	16	7	539	4	501	2e-55	208
rs:WP_017099417	DNA topoisomerase III [Vibrio tasmaniensis].	28.62	566	365	15	7	548	5	555	2e-55	209
rs:WP_009592313	DNA topoisomerase III [Paenibacillus sp. HGF5].	29.77	571	326	17	7	550	5	527	2e-55	210
rs:WP_022408234	DNA topoisomerase [Clostridium sp. CAG:354].	28.93	560	353	16	7	532	6	554	2e-55	209
rs:WP_039254980	DNA topoisomerase III [Bacillus sp. Pc3].	29.72	572	325	18	3	539	2	531	2e-55	210
rs:WP_034307594	DNA topoisomerase III [Bacillus simplex].	28.52	540	352	13	7	530	4	525	2e-55	210
rs:WP_041556619	DNA topoisomerase III [Carnobacterium sp. 17-4].	31.40	570	350	18	5	556	4	550	2e-55	210
rs:WP_034697924	DNA topoisomerase [Enterococcus hirae].	29.97	584	363	17	5	563	3	565	3e-55	210
rs:WP_042569714	DNA topoisomerase III [Yersinia intermedia].	27.34	545	361	13	7	531	4	533	3e-55	209
rs:WP_010861635	DNA topoisomerase III [Enterococcus faecium].	30.36	583	364	18	5	563	3	567	3e-55	210
rs:WP_006829182	DNA topoisomerase III [Planococcus antarcticus].	28.67	558	354	16	5	548	3	530	3e-55	210
rs:WP_018949090	DNA topoisomerase III [Thioalkalivibrio sp. ALMg11].	29.43	547	353	11	7	540	5	531	3e-55	209
rs:WP_023559145	DNA topoisomerase III [Brevibacillus panacihumi].	30.82	571	339	22	3	548	2	541	3e-55	210
tr:A0A077UKC9_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.76	619	387	20	7	606	5	588	3e-55	210
rs:WP_045644513	DNA topoisomerase III [Peptococcaceae bacterium BRH_c4b].	30.94	556	335	19	7	539	5	534	3e-55	210
rs:WP_011888497	DNA topoisomerase III [Geobacillus thermodenitrificans].	28.34	561	362	15	4	544	1	541	3e-55	210
tr:A0A077W394_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.76	619	387	20	7	606	5	588	3e-55	210
rs:WP_031304488	DNA topoisomerase III [Bacillus amyloliquefaciens].	30.07	572	323	19	3	539	2	531	3e-55	210
rs:WP_011639937	DNA topoisomerase III [Syntrophomonas wolfei].	27.72	552	351	17	7	539	5	527	3e-55	210
rs:WP_017099216	DNA topoisomerase III [Vibrio tasmaniensis].	28.62	566	365	15	7	548	5	555	3e-55	209
rs:WP_017121484	DNA topoisomerase [Xanthomonas vasicola].	28.68	551	353	13	7	530	4	541	3e-55	209
rs:WP_017550814	DNA topoisomerase III [Bacillus coagulans].	29.48	553	338	16	3	530	2	527	3e-55	210
rs:WP_008880142	MULTISPECIES: DNA topoisomerase III [Geobacillus].	29.76	551	338	18	4	530	1	526	3e-55	210
rs:WP_017638522	DNA topoisomerase III [Staphylococcus sp. E463].	27.97	597	385	16	7	590	5	569	3e-55	210
rs:WP_013056933	DNA topoisomerase III [Bacillus megaterium].	29.10	543	337	13	7	544	5	504	3e-55	210
rs:WP_020367826	DNA topoisomerase III, partial [Staphylococcus epidermidis].	27.76	580	361	14	7	563	5	549	3e-55	207
tr:A0A077VP33_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.76	619	387	20	7	606	5	588	3e-55	210
rs:WP_009334925	DNA topoisomerase III [Bacillus sp. 2_A_57_CT2].	30.28	568	318	22	7	548	5	520	3e-55	210
rs:WP_026584089	DNA topoisomerase III [Bacillus sp. J33].	30.14	564	324	18	7	548	5	520	3e-55	210
rs:WP_025729379	DNA topoisomerase III [Bacillus ginsengihumi].	30.18	497	321	12	45	530	46	527	3e-55	210
rs:WP_010215518	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	31.18	449	280	10	120	549	1	439	3e-55	207
tr:A0A077V461_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.76	619	387	20	7	606	5	588	3e-55	210
rs:WP_024292272	MULTISPECIES: DNA topoisomerase III [Lachnoclostridium].	29.08	564	350	17	7	548	5	540	3e-55	210
rs:WP_019555143	hypothetical protein [Propionispira raffinosivorans].	28.90	557	352	15	1	539	1	531	3e-55	210
rs:WP_010296837	DNA topoisomerase III [Clostridium senegalense].	28.30	629	364	24	1	590	1	581	3e-55	210
rs:WP_031872959	DNA topoisomerase III, partial [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-55	208
rs:WP_034622892	DNA topoisomerase III [Bacillus safensis].	29.51	566	349	17	3	548	2	537	3e-55	210
rs:WP_038484294	DNA topoisomerase III [Bacillus lehensis].	28.83	562	346	16	7	548	6	533	3e-55	210
rs:WP_019414696	DNA topoisomerase III [Paenisporosarcina sp. TG20].	28.85	565	352	20	3	548	2	535	3e-55	210
rs:WP_017382134	DNA topoisomerase III [Paenisporosarcina sp. TG-14].	29.00	562	354	19	3	548	2	534	3e-55	210
rs:WP_045642169	DNA topoisomerase III [Peptococcaceae bacterium BRH_c8a].	30.42	549	342	16	7	539	8	532	3e-55	211
rs:WP_040735488	DNA topoisomerase III [Paenibacillus alvei].	28.25	584	340	19	7	557	5	542	3e-55	210
rs:WP_025383844	DNA topoisomerase III [Yersinia similis].	27.52	545	360	13	7	531	4	533	3e-55	209
rs:WP_046302819	DNA topoisomerase III [Grimontia sp. AD028].	28.72	564	363	16	7	549	5	550	3e-55	209
rs:WP_014370137	DNA topoisomerase III [Paenibacillus mucilaginosus].	30.81	581	326	18	7	555	5	541	3e-55	210
rs:WP_010330854	DNA topoisomerase III [Bacillus vallismortis].	30.00	570	326	18	3	539	2	531	4e-55	210
rs:WP_017161201	DNA topoisomerase [Xanthomonas axonopodis].	28.68	551	353	13	7	530	4	541	4e-55	209
rs:WP_017168798	DNA topoisomerase [Xanthomonas axonopodis].	28.68	551	353	13	7	530	4	541	4e-55	209
tr:A0A0B4ISV6_VIBHA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.65	562	373	11	8	549	5	558	4e-55	210
rs:WP_019484415	hypothetical protein, partial [Pseudomonas aeruginosa].	31.18	417	266	9	52	459	1	405	4e-55	203
tr:A0A077UU21_STAAU	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.76	619	387	20	7	606	5	588	4e-55	209
rs:WP_010136018	DNA topoisomerase III [Flavobacteriaceae bacterium S85].	28.80	559	348	17	8	550	5	529	4e-55	210
rs:WP_031887564	DNA topoisomerase III, partial [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-55	208
rs:WP_031877274	DNA topoisomerase III, partial [Staphylococcus aureus].	28.57	539	340	16	7	532	5	511	4e-55	206
rs:WP_034538694	DNA topoisomerase III [Carnobacterium inhibens].	30.21	566	355	16	7	555	5	547	4e-55	209
rs:WP_003332668	DNA topoisomerase [Bacillus azotoformans].	28.85	610	383	18	4	591	2	582	4e-55	209
rs:WP_004719880	DNA topoisomerase III [Yersinia ruckeri].	28.02	546	356	15	7	531	4	533	4e-55	208
rs:WP_035434243	DNA topoisomerase III [Bacillus sp. UNC322MFChir4.1].	28.78	556	357	17	7	548	4	534	5e-55	209
rs:WP_031904145	DNA topoisomerase III [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	5e-55	209
tr:K4ZT14_PAEAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.25	584	340	19	7	557	12	549	5e-55	209
rs:WP_017040350	DNA topoisomerase III [Vibrio genomosp. F10].	28.45	566	366	15	7	548	5	555	5e-55	209
tr:A9L6T8_SHEB9	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.62	547	349	13	8	530	5	539	5e-55	209
rs:WP_022446451	DNA topoisomerase III [Faecalibacterium sp. CAG:74].	27.39	566	363	12	5	548	4	543	5e-55	209
rs:WP_007785444	DNA topoisomerase III [Desulfosporosinus youngiae].	28.72	571	349	16	5	550	4	541	5e-55	209
rs:WP_034818146	DNA topoisomerase III [Exiguobacterium alkaliphilum].	29.48	536	348	13	7	530	4	521	5e-55	209
rs:WP_016778794	DNA topoisomerase III [Anaerophaga thermohalophila].	29.52	559	348	18	4	550	1	525	5e-55	210
rs:WP_033674734	DNA topoisomerase III [Bacillus gaemokensis].	29.80	557	350	19	7	548	4	534	5e-55	209
rs:WP_010737556	MULTISPECIES: DNA topoisomerase [Enterococcus].	29.79	584	364	17	5	563	3	565	5e-55	209
rs:WP_018474722	hypothetical protein [Echinicola pacifica].	29.89	542	330	16	8	531	5	514	5e-55	210
rs:WP_031378663	DNA topoisomerase III [Bacillus amyloliquefaciens].	30.53	570	323	19	3	539	2	531	5e-55	209
rs:WP_019210140	DNA topoisomerase III [Yersinia massiliensis].	27.52	545	360	14	7	531	4	533	5e-55	208
rs:WP_007132739	DNA topoisomerase III [Paenibacillus lactis].	28.64	625	371	19	7	603	5	582	5e-55	209
rs:WP_042596196	DNA topoisomerase III [Bacillus thuringiensis].	29.19	579	356	17	3	555	2	552	5e-55	209
rs:WP_045724140	DNA topoisomerase [Clostridium baratii].	27.76	616	382	21	7	590	5	589	6e-55	209
rs:WP_012575131	DNA topoisomerase III [Anoxybacillus flavithermus].	27.52	614	411	15	4	603	1	594	6e-55	209
rs:WP_011563738	DNA topoisomerase III [Rubrobacter xylanophilus].	28.24	556	357	16	7	544	4	535	6e-55	209
rs:WP_000766760	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	19	7	530	4	525	6e-55	209
rs:WP_024666679	DNA topoisomerase III, partial [Pseudomonas syringae].	33.87	437	261	10	130	548	1	427	6e-55	206
rs:WP_009271940	DNA topoisomerase III [Erysipelotrichaceae bacterium 3_1_53].	27.65	622	394	17	3	599	2	592	6e-55	209
rs:WP_029092222	hypothetical protein [Brochothrix thermosphacta].	29.74	548	334	17	7	531	5	524	6e-55	209
rs:WP_047211734	DNA topoisomerase III [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	6e-55	209
sp:TOP3_BACSK	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	31.26	563	333	20	7	548	6	535	6e-55	209
rs:WP_041616898	DNA topoisomerase III [Paenibacillus mucilaginosus].	30.34	580	330	17	7	555	5	541	6e-55	209
rs:WP_038562834	DNA topoisomerase III [Draconibacterium orientale].	29.81	540	330	17	7	531	2	507	6e-55	210
rs:WP_000838492	DNA topoisomerase III [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	6e-55	209
tr:H7FRM8_9FLAO	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.13	551	344	18	8	550	14	531	6e-55	210
rs:WP_009249709	DNA topoisomerase III [Lachnospiraceae bacterium 5_1_57FAA].	28.77	570	346	16	7	544	5	546	6e-55	209
rs:WP_042524880	DNA topoisomerase III [Yersinia ruckeri].	28.02	546	356	15	7	531	4	533	6e-55	208
rs:WP_025231015	DNA topoisomerase III [Clostridium sp. ASBs410].	29.03	565	349	16	7	548	5	540	6e-55	209
rs:WP_021989105	DNA topoisomerase III [Odoribacter sp. CAG:788].	30.11	538	327	18	8	531	5	507	7e-55	209
rs:WP_006190863	DNA topoisomerase 3 [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	7e-55	209
rs:WP_000838493	DNA topoisomerase III [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	7e-55	209
rs:WP_017104047	DNA topoisomerase III [Vibrio tasmaniensis].	28.62	566	365	15	7	548	5	555	7e-55	208
rs:WP_023490164	DNA topoisomerase 3 [Serratia sp. DD3].	27.52	545	360	13	7	531	4	533	7e-55	208
rs:WP_044910184	hypothetical protein, partial [Lachnospiraceae bacterium MC2017].	30.93	582	346	22	7	550	5	568	7e-55	208
rs:WP_024120262	DNA topoisomerase III [Bacillus mojavensis].	30.00	570	326	18	3	539	2	531	7e-55	209
rs:WP_032494930	DNA topoisomerase [Enterococcus faecium].	29.62	547	347	17	5	531	33	561	7e-55	207
rs:WP_045418085	DNA topoisomerase III [Vibrio owensii].	28.88	561	371	12	8	549	5	556	7e-55	209
rs:WP_035386680	DNA topoisomerase III, partial [Exiguobacterium sp. S17].	30.22	536	344	14	7	530	4	521	8e-55	208
rs:WP_041089158	DNA topoisomerase III [Bacillus pumilus].	29.33	566	350	17	3	548	2	537	8e-55	209
rs:WP_033166191	DNA topoisomerase III [Clostridium sp. KNHs205].	28.85	558	352	17	7	548	5	533	8e-55	209
rs:WP_041106477	DNA topoisomerase III [Bacillus pumilus].	29.86	566	347	18	3	548	2	537	8e-55	209
rs:WP_000838496	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	8e-55	209
rs:WP_040473791	DNA topoisomerase III [Flavobacterium frigoris].	30.13	551	344	18	8	550	5	522	8e-55	209
sp:TOP3_STAAR	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	28.52	568	358	18	7	559	5	539	8e-55	209
rs:WP_001991674	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	18	7	530	4	525	8e-55	209
rs:WP_015757378	DNA topoisomerase III [Desulfotomaculum acetoxidans].	27.93	623	355	18	7	559	5	603	8e-55	209
rs:WP_031922615	DNA topoisomerase III [Staphylococcus aureus].	30.22	556	347	15	5	544	3	533	8e-55	209
rs:WP_000838476	DNA topoisomerase III [Staphylococcus aureus].	28.43	619	389	20	7	606	5	588	8e-55	209
tr:A0A098ESY6_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.47	541	352	14	7	530	6	528	8e-55	209
rs:WP_017038719	DNA topoisomerase III [Vibrio genomosp. F10].	28.40	574	356	15	7	548	5	555	8e-55	208
rs:WP_031885094	DNA topoisomerase III [Staphylococcus aureus].	30.32	554	352	16	3	544	2	533	8e-55	209
rs:WP_036640886	DNA topoisomerase III [Paenibacillus sp. FSL R5-808].	29.23	626	363	20	7	602	5	580	8e-55	209
rs:WP_024305832	topoisomerase I [Lactobacillus rhamnosus].	30.53	583	364	18	5	563	3	568	8e-55	209
rs:WP_042513583	DNA topoisomerase III, partial [Bacillus cereus].	29.91	535	343	18	7	526	4	521	9e-55	205
rs:WP_002316073	DNA topoisomerase [Enterococcus faecium].	29.67	583	368	17	5	563	3	567	9e-55	209
rs:WP_000838504	DNA topoisomerase III [Staphylococcus aureus].	28.70	568	357	18	7	559	5	539	9e-55	209
rs:WP_022302692	DNA topoisomerase [Firmicutes bacterium CAG:227].	29.02	572	344	17	7	548	5	544	9e-55	209
rs:WP_000539255	DNA topoisomerase III [Bacillus cereus].	29.02	579	357	17	3	555	2	552	9e-55	209
rs:WP_000838502	DNA topoisomerase 3 [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	9e-55	209
rs:WP_045761400	DNA topoisomerase III [Xanthomonas albilineans].	28.28	548	360	14	8	539	5	535	9e-55	209
rs:WP_034806015	DNA topoisomerase III [Exiguobacterium sp. AB2].	29.48	536	348	13	7	530	4	521	9e-55	209
rs:WP_041116726	DNA topoisomerase III [Bacillus pumilus].	29.86	566	347	18	3	548	2	537	9e-55	209
rs:WP_024427348	DNA topoisomerase III [Bacillus pumilus].	29.86	566	347	18	3	548	2	537	9e-55	209
rs:WP_010283960	DNA topoisomerase III [Bacillus timonensis].	29.13	563	354	16	4	544	1	540	9e-55	209
rs:WP_026045081	DNA topoisomerase [Burkholderia pyrrocinia].	30.10	525	333	14	48	547	43	558	9e-55	208
rs:WP_039811820	DNA topoisomerase III [Jeotgalibacillus sp. D5].	29.80	547	342	16	5	539	4	520	9e-55	209
rs:WP_046955042	DNA topoisomerase III [Bacillus cereus].	30.80	539	341	19	7	530	4	525	9e-55	209
rs:WP_003625660	DNA topoisomerase III [Lactobacillus helveticus].	30.02	593	351	20	5	563	3	565	9e-55	209
rs:WP_034283847	DNA topoisomerase III [Bacillus safensis].	29.86	566	347	18	3	548	2	537	9e-55	209
rs:WP_000838483	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	1e-54	208
rs:WP_000838509	DNA topoisomerase III [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	1e-54	208
rs:WP_045844069	DNA topoisomerase III [Yersinia ruckeri].	28.02	546	356	15	7	531	4	533	1e-54	207
rs:WP_006094529	MULTISPECIES: DNA topoisomerase III [Bacillus].	28.72	564	347	17	7	548	4	534	1e-54	208
rs:WP_008881726	DNA topoisomerase III [Geobacillus sp. G11MC16].	27.99	561	364	15	4	544	1	541	1e-54	208
rs:WP_002585520	DNA topoisomerase III [[Clostridium] clostridioforme].	30.22	546	328	17	7	539	4	509	1e-54	208
rs:WP_000217286	DNA topoisomerase III [Bacillus cereus].	30.80	539	341	18	7	530	5	526	1e-54	208
rs:WP_043070392	hypothetical protein, partial [Aneurinibacillus migulanus].	29.12	625	394	19	7	603	4	607	1e-54	209
rs:WP_035295670	DNA topoisomerase III, partial [Brevibacillus thermoruber].	28.68	544	353	13	4	530	1	526	1e-54	208
tr:F8F5Y2_PAEMK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.34	580	330	17	7	555	32	568	1e-54	209
sp:TOP3_STAAB	RecName: Full=Putative DNA topoisomerase 3; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	28.52	568	358	18	7	559	5	539	1e-54	208
rs:WP_043040358	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	1e-54	208
rs:WP_040414532	DNA topoisomerase III [Cyclobacterium qasimii].	30.12	561	346	18	8	557	5	530	1e-54	209
gpu:CP009300_2741	DNA topoisomerase III family protein [Bacillus cereus D17]	29.85	536	344	18	7	527	4	522	1e-54	205
rs:WP_031865861	DNA topoisomerase III [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	1e-54	208
tr:A0A078BQ75_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.57	541	341	14	7	531	4	520	1e-54	208
rs:WP_038460655	MULTISPECIES: DNA topoisomerase III [Bacillus subtilis group].	29.90	572	324	19	3	539	2	531	1e-54	209
rs:WP_000838505	DNA topoisomerase 3 [Staphylococcus aureus].	28.70	568	357	18	7	559	5	539	1e-54	208
rs:WP_001573525	DNA topoisomerase 3 [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	1e-54	208
rs:WP_000838488	DNA topoisomerase III [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	1e-54	208
rs:WP_044115552	DNA topoisomerase III [Porphyromonas sp. KLE 1280].	28.82	569	348	19	7	546	2	542	1e-54	208
rs:WP_044909789	DNA topoisomerase III [Lachnospiraceae bacterium MC2017].	29.06	554	339	18	7	547	4	516	1e-54	208
rs:WP_003156261	MULTISPECIES: DNA topoisomerase III [Bacillales].	29.90	572	324	19	3	539	2	531	1e-54	209
rs:WP_020366414	DNA topoisomerase III [Staphylococcus epidermidis].	27.22	632	380	16	7	606	5	588	1e-54	208
rs:WP_000838498	DNA topoisomerase 3 [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	1e-54	208
rs:WP_003699035	DNA topoisomerase [Lactobacillus salivarius].	28.84	579	361	17	5	558	3	555	1e-54	208
rs:WP_029575269	DNA topoisomerase III [Bacillus siamensis].	29.90	572	324	19	3	539	2	531	1e-54	208
rs:WP_012301124	TrsI protein [Geobacillus stearothermophilus].	27.99	561	364	15	4	544	1	541	1e-54	208
rs:WP_000766762	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	17	7	530	4	525	1e-54	208
rs:WP_000838489	DNA topoisomerase 3 [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	1e-54	208
rs:WP_000766739	DNA topoisomerase III [Bacillus thuringiensis].	30.61	539	342	18	7	530	4	525	1e-54	208
rs:WP_046959122	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	19	7	530	4	525	1e-54	208
rs:WP_022035697	DNA topoisomerase III [Roseburia sp. CAG:50].	27.27	561	349	16	5	539	4	531	1e-54	208
rs:WP_012952161	DNA topoisomerase III [Listeria monocytogenes].	29.90	572	332	19	7	544	5	541	1e-54	208
rs:WP_040600277	hypothetical protein, partial [Sphingobium ummariense].	30.72	573	334	20	1	546	1	537	1e-54	207
rs:WP_034945828	DNA topoisomerase III, partial [Erwinia oleae].	33.33	381	238	7	8	383	5	374	1e-54	201
rs:WP_038462366	MULTISPECIES: DNA topoisomerase III [Bacillus subtilis group].	29.90	572	324	19	3	539	2	531	1e-54	208
gp:CP006890_411	DNA topoisomerase III [Bacillus amyloliquefaciens SQR9]	29.90	572	324	19	3	539	12	541	1e-54	208
rs:WP_000838506	DNA topoisomerase 3 [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	1e-54	208
rs:WP_044290852	DNA topoisomerase III [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	1e-54	208
gp:HE774679_385	DNA topoisomerase III [Bacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2]	29.90	572	324	19	3	539	10	539	1e-54	208
rs:WP_000838487	DNA topoisomerase 3 [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	1e-54	208
rs:WP_045576535	DNA topoisomerase III, partial [Desulfosporosinus sp. I2].	28.13	615	381	20	5	590	4	586	1e-54	208
tr:I2C1H1_BACAM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.90	572	324	19	3	539	12	541	1e-54	208
tr:S3IA68_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.77	546	345	19	1	530	1	529	1e-54	208
rs:WP_029434626	DNA topoisomerase III [Bilophila wadsworthia].	29.87	539	345	16	7	531	4	523	1e-54	208
rs:WP_026477045	DNA topoisomerase III [Alkaliphilus transvaalensis].	28.99	583	345	20	1	534	1	563	1e-54	207
rs:WP_035407321	DNA topoisomerase III [Bacillus sp. SJS].	29.89	562	348	19	3	548	2	533	1e-54	208
rs:WP_017169969	DNA topoisomerase [Xanthomonas axonopodis].	28.49	551	354	13	7	530	4	541	1e-54	207
rs:WP_000540560	DNA topoisomerase III [Bacillus thuringiensis].	30.80	539	341	18	7	530	6	527	1e-54	208
rs:WP_020977494	DNA topoisomerase 3 [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	1e-54	208
rs:WP_033861666	DNA topoisomerase III, partial [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	1e-54	207
rs:WP_033575096	DNA topoisomerase III [Bacillus amyloliquefaciens].	29.90	572	324	19	3	539	2	531	1e-54	208
rs:WP_031928915	DNA topoisomerase III [Staphylococcus aureus].	28.40	567	360	16	7	559	5	539	1e-54	208
rs:WP_000838500	DNA topoisomerase III [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	1e-54	208
rs:WP_010729522	DNA topoisomerase III [Enterococcus faecium].	29.50	583	369	18	5	563	3	567	1e-54	207
rs:WP_000766746	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	19	7	530	4	525	1e-54	208
gp:HF563562_395	DNA topoisomerase III [Bacillus amyloliquefaciens subsp. plantarum UCMB5036]	29.90	572	324	19	3	539	12	541	1e-54	208
tr:S6FW61_BACAM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.90	572	324	19	3	539	12	541	1e-54	208
rs:WP_000766757	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	19	7	530	4	525	1e-54	208
rs:WP_000838497	DNA topoisomerase 3 [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	1e-54	208
rs:WP_000838475	DNA topoisomerase III [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	1e-54	208
rs:WP_046935705	DNA topoisomerase [Xanthomonas euvesicatoria].	28.83	548	354	12	7	530	4	539	1e-54	208
rs:WP_026092310	DNA topoisomerase III [Bacillus amyloliquefaciens].	29.90	572	324	19	3	539	2	531	1e-54	208
rs:WP_015900982	DNA topoisomerase III [Staphylococcus carnosus].	28.19	564	364	16	7	559	5	538	1e-54	208
rs:WP_029326219	MULTISPECIES: DNA topoisomerase III [Bacillus].	29.90	572	324	19	3	539	2	531	2e-54	208
tr:J8GVI6_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.02	579	357	17	3	555	76	626	2e-54	209
rs:WP_029593788	DNA topoisomerase [Enterococcus faecium].	29.36	579	373	15	5	563	3	565	2e-54	208
rs:WP_022090677	DNA topoisomerase III [Clostridium sp. CAG:492].	28.87	568	350	19	7	532	6	561	2e-54	207
rs:WP_000766737	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	18	7	530	4	525	2e-54	208
rs:WP_007579075	DNA topoisomerase III [Patulibacter medicamentivorans].	29.24	602	344	22	5	548	4	581	2e-54	209
rs:WP_045640846	DNA topoisomerase III [Flavobacteriales bacterium BRH_c54].	30.63	555	336	18	8	550	5	522	2e-54	208
rs:WP_016104534	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	19	7	530	4	525	2e-54	208
rs:WP_000766758	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	19	7	530	4	525	2e-54	208
rs:WP_039176652	DNA topoisomerase III [Bacillus sp. WP8].	29.33	566	350	17	3	548	2	537	2e-54	208
rs:WP_000838501	DNA topoisomerase III [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	2e-54	208
rs:WP_010073946	DNA topoisomerase III [Clostridium cellulovorans].	28.42	577	366	16	3	559	2	551	2e-54	208
rs:WP_000838486	DNA topoisomerase 3 [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	2e-54	208
rs:WP_016622814	DNA topoisomerase, partial [Enterococcus faecalis].	30.25	552	337	20	5	531	3	531	2e-54	205
rs:WP_022213677	DNA topoisomerase [Blautia sp. CAG:237].	28.10	548	346	17	7	532	5	526	2e-54	208
rs:WP_031795571	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	2e-54	208
tr:T0IXR4_9SPHN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	30.72	573	334	20	1	546	1	537	2e-54	207
rs:WP_037536003	DNA topoisomerase III [Staphylococcus haemolyticus].	27.41	613	380	21	7	598	5	573	2e-54	207
rs:WP_000766780	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	19	7	530	4	525	2e-54	208
rs:WP_002450320	DNA topoisomerase III [Staphylococcus warneri].	28.41	602	376	18	7	590	5	569	2e-54	207
rs:WP_003188538	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.43	539	343	18	7	530	4	525	2e-54	207
rs:WP_028402778	DNA topoisomerase III [Bacillus panaciterrae].	28.21	624	398	19	4	603	1	598	2e-54	208
rs:WP_029099989	DNA topoisomerase III [Brevibacillus thermoruber].	28.86	544	352	13	4	530	1	526	2e-54	208
rs:WP_043352648	DNA topoisomerase III [Bacillus cereus].	30.80	539	341	18	7	530	5	526	2e-54	207
rs:WP_026690239	DNA topoisomerase III [Bacillus aurantiacus].	29.07	571	347	18	7	548	4	545	2e-54	208
rs:WP_025284251	DNA topoisomerase III [Bacillus amyloliquefaciens].	29.72	572	325	19	3	539	2	531	2e-54	208
rs:WP_000766772	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	18	7	530	4	525	2e-54	207
rs:WP_047203830	DNA topoisomerase III [Bacillus pumilus].	29.33	566	350	17	3	548	2	537	2e-54	208
rs:WP_000766779	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	19	7	530	4	525	2e-54	207
rs:WP_040104610	DNA topoisomerase III [Salinicoccus roseus].	28.47	562	358	14	5	549	4	538	2e-54	208
rs:WP_002322737	DNA topoisomerase [Enterococcus faecium].	29.19	579	374	15	5	563	3	565	2e-54	208
rs:WP_002354426	DNA topoisomerase [Enterococcus faecium].	29.85	583	367	18	5	563	3	567	2e-54	208
rs:WP_003398165	DNA topoisomerase III [Anoxybacillus flavithermus].	27.52	625	398	20	4	603	1	595	2e-54	207
rs:WP_031672442	hypothetical protein [Listeria monocytogenes].	30.07	572	331	19	7	544	5	541	2e-54	207
rs:WP_028593375	DNA topoisomerase III [Paenibacillus assamensis].	28.62	566	336	19	7	550	5	524	2e-54	207
rs:WP_045368045	DNA topoisomerase III [Vibrio campbellii].	28.92	567	365	13	8	549	5	558	2e-54	208
rs:WP_002202402	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	19	7	530	4	525	2e-54	207
rs:WP_036131029	DNA topoisomerase III [Marinobacter sp. AK21].	26.74	617	415	16	8	602	5	606	2e-54	207
rs:WP_044564917	DNA topoisomerase [Anaerococcus sp. 9402080].	29.73	565	323	18	7	551	4	514	2e-54	205
rs:WP_002503703	DNA topoisomerase III [Staphylococcus epidermidis].	27.27	627	386	16	7	606	5	588	2e-54	207
rs:WP_002118313	DNA topoisomerase III [Bacillus cereus].	30.43	539	343	19	7	530	4	525	2e-54	207
rs:WP_037541589	DNA topoisomerase III [Staphylococcus caprae].	28.24	609	380	19	7	598	5	573	2e-54	207
rs:WP_031874900	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	2e-54	207
rs:WP_045465464	DNA topoisomerase III [Burkholderiales bacterium GJ-E10].	29.25	547	348	13	7	539	4	525	2e-54	207
rs:WP_010248082	DNA topoisomerase III [Peptoniphilus rhinitidis].	29.56	565	324	18	7	551	4	514	2e-54	205
rs:WP_021859574	DNA topoisomerase [Dorea sp. CAG:105].	27.30	575	351	15	7	539	5	554	2e-54	208
gp:CP010941_2189	DNA topoisomerase III [Staphylococcus aureus]	28.52	568	358	18	7	559	5	539	2e-54	207
rs:WP_028168975	DNA topoisomerase III [Bradyrhizobium elkanii].	27.34	567	362	12	7	553	6	542	2e-54	208
tr:C5QM86_9STAP	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.24	609	380	19	7	598	6	574	2e-54	207
rs:WP_033690675	DNA topoisomerase, partial [Pseudomonas sp. TJI-51].	30.78	497	298	14	72	532	1	487	2e-54	206
rs:WP_000766783	DNA topoisomerase III [Bacillus cereus].	30.52	557	346	19	7	548	4	534	2e-54	207
tr:I2HML6_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.90	572	324	19	3	539	12	541	2e-54	207
rs:WP_031911617	DNA topoisomerase III [Staphylococcus aureus].	28.75	567	358	18	7	559	5	539	2e-54	207
rs:WP_017166887	DNA topoisomerase [Xanthomonas axonopodis].	28.68	551	353	13	7	530	4	541	2e-54	207
rs:WP_012116832	DNA topoisomerase III [Bacillus amyloliquefaciens].	29.72	572	325	19	3	539	2	531	2e-54	207
rs:WP_000766773	DNA topoisomerase III [Bacillus cereus].	30.93	540	339	19	7	530	4	525	2e-54	207
rs:WP_000766733	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	19	7	530	4	525	2e-54	207
rs:WP_022076992	DNA topoisomerase III [Clostridium sp. CAG:571].	27.85	571	353	18	7	532	6	562	2e-54	206
rs:WP_031795285	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	2e-54	207
rs:WP_044899422	DNA topoisomerase III [Aeribacillus pallidus].	28.68	544	353	13	4	530	1	526	2e-54	207
rs:WP_002086236	DNA topoisomerase III [Bacillus cereus].	30.43	539	343	19	7	530	4	525	2e-54	207
rs:WP_022151843	DNA topoisomerase [Lachnospiraceae bacterium CAG:215].	28.75	567	344	16	7	539	5	545	2e-54	207
rs:WP_005430719	DNA topoisomerase III [Vibrio campbellii].	28.90	564	369	12	8	549	5	558	2e-54	207
rs:WP_044169014	DNA topoisomerase III [Porphyromonas catoniae].	27.48	564	362	14	7	546	2	542	2e-54	207
rs:WP_038486162	DNA topoisomerase III, partial [Bacillus lehensis].	29.72	572	358	18	5	555	3	551	2e-54	207
tr:X4BAN5_SALEN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	28.24	517	344	13	7	507	4	509	3e-54	204
tr:V1WH61_SALMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.06	446	269	12	170	590	8	444	3e-54	204
rs:WP_000766747	DNA topoisomerase III [Bacillus cereus].	29.87	539	346	18	7	530	4	525	3e-54	207
rs:WP_018339522	DNA topoisomerase III [Butyricimonas synergistica].	30.09	545	334	19	8	539	5	515	3e-54	207
rs:WP_031910301	DNA topoisomerase III, partial [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	207
rs:WP_000766748	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	29.87	539	346	18	7	530	4	525	3e-54	207
rs:WP_035197261	DNA topoisomerase [Bacillus azotoformans].	28.85	610	383	18	4	591	2	582	3e-54	207
rs:WP_000766769	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	18	7	530	4	525	3e-54	207
tr:A0A0C5J2H9_9RHOO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AJP49262.1};	29.96	564	360	17	7	550	6	554	3e-54	208
rs:WP_002012275	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.43	539	343	19	7	530	4	525	3e-54	207
gp:CP006845_416	DNA topoisomerase III [Bacillus amyloliquefaciens CC178]	29.72	572	325	19	3	539	10	539	3e-54	207
rs:WP_000766749	DNA topoisomerase III [Bacillus thuringiensis].	29.87	539	346	18	7	530	4	525	3e-54	207
tr:A0A0D5MB95_ENTFC	SubName: Full=Topoisomerase 1A {ECO:0000313|EMBL:AJY53540.1};	29.85	583	367	18	5	563	3	567	3e-54	207
rs:WP_000838508	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	207
rs:WP_032870446	MULTISPECIES: DNA topoisomerase III [Bacillus].	29.72	572	325	19	3	539	2	531	3e-54	207
rs:WP_000766753	DNA topoisomerase III [Bacillus cereus].	29.87	539	346	18	7	530	4	525	3e-54	207
rs:WP_046463202	DNA topoisomerase III [Staphylococcus aureus].	28.52	568	358	18	7	559	5	539	3e-54	207
rs:WP_000766763	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	18	7	530	4	525	3e-54	207
rs:WP_027089380	DNA topoisomerase III [[Clostridium] saccharogumia].	29.32	573	358	19	5	559	4	547	3e-54	207
rs:WP_029334830	DNA topoisomerase III [Exiguobacterium aurantiacum].	29.29	536	349	14	7	530	4	521	3e-54	207
tr:D4LXB5_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.13	551	341	16	7	532	5	525	3e-54	207
rs:WP_031811521	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	207
rs:WP_000838503	DNA topoisomerase 3 [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	207
rs:WP_033859118	DNA topoisomerase 3 [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	207
rs:WP_031911917	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	207
rs:WP_021286089	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	207
rs:WP_025729328	DNA topoisomerase III [Bacillus ginsengihumi].	29.39	558	310	20	7	539	5	503	3e-54	207
rs:WP_037589019	DNA topoisomerase III [Staphylococcus aureus].	27.88	581	346	18	7	559	5	540	3e-54	207
rs:WP_000063789	DNA topoisomerase [Bacillus cereus].	29.73	565	347	17	7	544	6	547	3e-54	207
rs:WP_002333268	MULTISPECIES: DNA topoisomerase [Enterococcus].	29.19	579	374	15	5	563	3	565	3e-54	207
rs:WP_025477629	DNA topoisomerase [Enterococcus faecium].	29.19	579	374	15	5	563	3	565	3e-54	207
rs:WP_023914047	DNA topoisomerase 3 [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	207
rs:WP_031890145	DNA topoisomerase 3 [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	207
rs:WP_031775289	DNA topoisomerase 3 [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	207
rs:WP_007410181	DNA topoisomerase III [Bacillus sp. 916].	29.72	572	325	19	3	539	2	531	3e-54	207
rs:WP_022030218	DNA topoisomerase [Clostridium hathewayi CAG:224].	29.30	570	348	16	7	548	5	547	3e-54	207
rs:WP_026901859	DNA topoisomerase [Peptostreptococcaceae bacterium VA2].	30.20	596	377	17	7	590	4	572	3e-54	207
rs:WP_025481902	DNA topoisomerase [Enterococcus faecium].	29.19	579	374	15	5	563	3	565	3e-54	207
rs:WP_022739163	DNA topoisomerase III [Laceyella sacchari].	31.21	564	339	18	7	548	4	540	3e-54	207
rs:WP_017167698	DNA topoisomerase [Xanthomonas axonopodis].	28.13	551	356	12	7	530	4	541	3e-54	207
rs:WP_004605342	DNA topoisomerase III [[Clostridium] scindens].	28.42	570	348	15	7	544	5	546	3e-54	207
rs:WP_016221561	DNA topoisomerase III [Dorea sp. 5-2].	28.62	566	349	16	7	544	5	543	3e-54	207
rs:WP_044477171	DNA topoisomerase III [Paenibacillus sp. GD11].	29.24	578	341	18	5	559	3	535	3e-54	207
rs:WP_033851494	DNA topoisomerase III, partial [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	207
tr:A0A0E1NYZ3_BACAM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AJK64203.1};	29.72	572	325	19	3	539	12	541	3e-54	207
rs:WP_031922391	DNA topoisomerase III, partial [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	206
rs:WP_035652017	hypothetical protein, partial [Lachnospiraceae bacterium AC3007].	28.53	652	389	22	5	596	4	638	3e-54	206
rs:WP_031925301	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	207
rs:WP_031921997	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	207
rs:WP_031861717	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	207
rs:WP_031900030	DNA topoisomerase III, partial [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	3e-54	207
rs:WP_002296700	DNA topoisomerase [Enterococcus faecium].	29.19	579	374	15	5	563	62	624	3e-54	207
rs:WP_034692209	DNA topoisomerase I [Chryseobacterium sp. CF365].	29.07	571	348	17	7	552	4	542	4e-54	207
tr:A0A060M1P7_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.72	572	358	18	5	555	3	551	4e-54	207
rs:WP_031913504	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
tr:R7TCT6_CAPTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.61	446	268	10	114	531	1	437	4e-54	202
rs:WP_002158311	DNA topoisomerase III [Bacillus cereus].	30.43	539	343	19	7	530	4	525	4e-54	207
rs:WP_031902343	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
sp:TOP3_STAA8	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	28.35	568	359	18	7	559	5	539	4e-54	207
sp:TOP3_STAA3	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	28.35	568	359	18	7	559	5	539	4e-54	207
rs:WP_044335056	DNA topoisomerase III [Bacillus safensis].	29.33	566	350	17	3	548	2	537	4e-54	207
rs:WP_003145958	DNA topoisomerase III [Gemella haemolysans].	29.47	570	330	19	5	548	3	526	4e-54	207
rs:WP_034759339	DNA topoisomerase III [Bacillus vietnamensis].	28.55	564	354	16	4	548	1	534	4e-54	207
rs:WP_031911155	DNA topoisomerase 3 [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
rs:WP_031907119	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
rs:WP_000838478	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
rs:WP_024425570	DNA topoisomerase III [Bacillus safensis].	29.33	566	350	17	3	548	2	537	4e-54	207
rs:WP_000766778	DNA topoisomerase III [Bacillus cereus].	29.87	539	346	18	7	530	4	525	4e-54	207
rs:WP_031906579	DNA topoisomerase 3 [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
rs:WP_000766738	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.61	539	342	18	7	530	4	525	4e-54	207
rs:WP_000766751	DNA topoisomerase III [Bacillus cereus].	30.00	540	344	19	7	530	4	525	4e-54	207
rs:WP_031789086	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
rs:WP_039702391	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
rs:WP_015239170	DNA topoisomerase III [Bacillus amyloliquefaciens].	29.72	572	325	19	3	539	2	531	4e-54	207
rs:WP_025093607	DNA topoisomerase III [Bacillus pumilus].	29.86	566	347	18	3	548	2	537	4e-54	207
rs:WP_039314343	DNA topoisomerase [Clostridium baratii].	27.60	616	383	21	7	590	5	589	4e-54	207
rs:WP_000766771	MULTISPECIES: DNA topoisomerase III [Bacillus].	30.61	539	342	18	7	530	4	525	4e-54	207
rs:WP_000766764	DNA topoisomerase III [Bacillus cereus].	30.43	539	343	18	7	530	4	525	4e-54	207
rs:WP_000766745	DNA topoisomerase III [Bacillus cereus].	31.17	539	339	19	7	530	4	525	4e-54	207
rs:WP_000838480	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
rs:WP_001549680	DNA topoisomerase 3 [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
rs:WP_031911198	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
rs:WP_041481943	DNA topoisomerase III [Bacillus amyloliquefaciens].	29.90	572	324	19	3	539	2	531	4e-54	207
rs:WP_044584352	DNA topoisomerase III [Bacillus bombysepticus].	30.43	539	343	18	7	530	4	525	4e-54	207
rs:WP_002148790	DNA topoisomerase III [Bacillus cereus].	30.43	539	343	19	7	530	4	525	4e-54	207
rs:WP_031833533	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
rs:WP_031807777	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
rs:WP_026701296	hypothetical protein [Bacillus aidingensis].	28.70	575	361	19	7	556	5	555	4e-54	207
rs:WP_024344937	DNA topoisomerase III [[Clostridium] methoxybenzovorans].	28.80	566	349	17	7	548	5	540	4e-54	207
rs:WP_031832724	DNA topoisomerase 3 [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
tr:F0E713_PSEDT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.58	497	299	14	72	532	1	487	4e-54	206
rs:WP_002475810	DNA topoisomerase III [Staphylococcus epidermidis].	27.11	627	387	16	7	606	5	588	4e-54	207
rs:WP_031793812	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
rs:WP_031598690	DNA topoisomerase III [Ferrovum myxofaciens].	29.76	541	337	17	7	531	4	517	4e-54	207
rs:WP_000766761	DNA topoisomerase III [Bacillus cereus].	30.43	539	343	19	7	530	4	525	4e-54	207
rs:WP_006771625	DNA topoisomerase III [[Clostridium] hathewayi].	29.30	570	348	16	7	548	5	547	4e-54	207
rs:WP_000766734	MULTISPECIES: DNA topoisomerase III [Bacillus].	30.61	539	342	18	7	530	4	525	4e-54	207
rs:WP_023604926	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	4e-54	207
rs:WP_002200885	DNA topoisomerase III [Bacillus cereus].	30.43	539	343	19	7	530	4	525	4e-54	207
rs:WP_000766750	DNA topoisomerase III [Bacillus cereus].	29.87	539	346	18	7	530	4	525	4e-54	207
rs:WP_031796011	DNA topoisomerase 3 [Staphylococcus aureus].	28.22	567	361	17	7	559	5	539	4e-54	207
rs:WP_040155132	DNA topoisomerase III [Yersinia ruckeri].	27.68	542	363	14	7	531	4	533	4e-54	206
rs:WP_000766770	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	18	7	530	4	525	4e-54	207
rs:YP_028031	DNA topoisomerase III [Bacillus anthracis str. Sterne].	30.34	557	347	19	7	548	4	534	4e-54	207
rs:WP_002447325	DNA topoisomerase III [Staphylococcus epidermidis].	27.11	627	387	16	7	606	5	588	4e-54	207
tr:G4BEE6_AGGAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.93	485	297	18	7	468	4	473	4e-54	203
rs:WP_039721732	topoisomerase I [Methylacidiphilum kamchatkense].	28.90	557	367	13	5	544	4	548	4e-54	207
rs:WP_025783241	DNA topoisomerase III [Sporosarcina sp. D27].	29.36	562	352	20	3	548	2	534	4e-54	207
rs:WP_046467158	DNA topoisomerase III [Staphylococcus pasteuri].	27.64	597	387	16	7	590	5	569	4e-54	207
rs:WP_044466810	DNA topoisomerase III [Staphylococcus caprae].	28.08	609	381	19	7	598	5	573	4e-54	206
rs:WP_031885526	DNA topoisomerase III [Staphylococcus aureus].	28.22	567	361	17	7	559	5	539	4e-54	206
rs:WP_010729361	DNA topoisomerase III [Enterococcus faecium].	29.50	583	369	17	5	563	3	567	4e-54	206
rs:WP_002457943	DNA topoisomerase III [Staphylococcus epidermidis].	27.11	627	387	16	7	606	5	588	5e-54	206
rs:WP_022484510	DNA topoisomerase [Clostridium sp. CAG:389].	27.69	603	379	17	7	560	6	600	5e-54	206
rs:WP_041167430	DNA topoisomerase [Pseudomonas putida].	30.58	497	299	14	72	532	1	487	5e-54	206
rs:WP_000838494	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	5e-54	206
rs:WP_040266123	DNA topoisomerase III [Serratia symbiotica].	27.79	547	356	14	7	531	4	533	5e-54	206
rs:WP_010662622	DNA topoisomerase III [Marinilabilia salmonicolor].	28.81	611	380	21	8	602	5	576	5e-54	207
rs:WP_039042718	DNA topoisomerase III [Sporosarcina sp. ZBG7A].	29.00	562	354	19	3	548	2	534	5e-54	207
rs:WP_043071384	DNA topoisomerase III [Aneurinibacillus migulanus].	28.23	620	394	17	4	599	1	593	5e-54	207
rs:WP_000838482	DNA topoisomerase 3 [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	5e-54	206
rs:WP_007428825	DNA topoisomerase III [Paenibacillus sp. Aloe-11].	28.45	566	329	18	7	544	5	522	5e-54	206
gpu:CP011686_415	DNA topoisomerase III [Bacillus amyloliquefaciens]	29.72	572	325	19	3	539	12	541	5e-54	207
rs:WP_000766765	DNA topoisomerase III [Bacillus cereus].	30.43	539	343	18	7	530	4	525	5e-54	206
rs:WP_038275861	DNA topoisomerase III [Yersinia ruckeri].	27.84	546	357	15	7	531	4	533	5e-54	206
rs:WP_046044421	topoisomerase [Staphylococcus epidermidis].	27.27	627	386	16	7	606	5	588	5e-54	206
rs:WP_000766766	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.43	539	343	18	7	530	4	525	5e-54	206
rs:WP_021385145	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.29	560	323	17	7	544	6	514	5e-54	206
rs:WP_000838495	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	5e-54	206
rs:WP_017006904	DNA topoisomerase III [Enterovibrio norvegicus].	28.29	562	368	15	7	549	5	550	5e-54	206
rs:WP_032866976	DNA topoisomerase III [Bacillus amyloliquefaciens].	29.72	572	325	19	3	539	2	531	5e-54	206
rs:WP_002499566	DNA topoisomerase III [Staphylococcus epidermidis].	27.11	627	387	16	7	606	5	588	5e-54	206
rs:WP_000838473	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	5e-54	206
rs:WP_016958405	DNA topoisomerase III [Enterovibrio norvegicus].	28.29	562	368	15	7	549	5	550	5e-54	205
gp:HE617159_384	DNA topoisomerase III [Bacillus amyloliquefaciens subsp. plantarum CAU B946]	29.90	572	324	19	3	539	10	539	6e-54	206
rs:WP_046947023	DNA topoisomerase III [Bacillus cereus].	31.17	539	339	19	7	530	4	525	6e-54	206
tr:S4F4D5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.19	579	374	15	5	563	62	624	6e-54	207
rs:WP_000838490	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	6e-54	206
rs:WP_022415164	DNA topoisomerase [Dorea longicatena CAG:42].	28.25	584	347	17	7	539	5	567	6e-54	207
rs:WP_044947481	DNA topoisomerase III [Blautia schinkii].	28.73	550	341	14	7	532	5	527	6e-54	206
rs:WP_017004793	DNA topoisomerase III [Enterovibrio norvegicus].	28.29	562	368	15	7	549	5	550	6e-54	205
rs:WP_018758435	hypothetical protein [Paenibacillus terrigena].	27.97	597	337	19	5	563	3	544	6e-54	206
rs:WP_002491551	DNA topoisomerase III [Staphylococcus epidermidis].	27.11	627	387	16	7	606	5	588	6e-54	206
rs:WP_022620845	DNA topoisomerase type IA Tn1549-like CTn5-Orf16 [Peptoclostridium difficile].	29.20	565	326	18	7	551	4	514	6e-54	204
rs:WP_025906799	DNA topoisomerase III [Staphylococcus sciuri].	28.06	581	345	18	7	559	5	540	6e-54	206
rs:WP_027640143	DNA topoisomerase [Clostridium cadaveris].	29.67	610	378	21	7	590	5	589	6e-54	206
rs:WP_026559271	DNA topoisomerase III [Bacillus sp. J37].	30.37	563	339	18	7	548	4	534	6e-54	206
rs:WP_031866479	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	6e-54	206
rs:WP_046099940	DNA topoisomerase III [Staphylococcus carnosus].	28.01	564	365	16	7	559	5	538	7e-54	206
rs:WP_035326368	DNA topoisomerase III [Bacillus firmus].	29.68	566	324	20	7	548	5	520	7e-54	206
rs:WP_000766735	DNA topoisomerase III [Bacillus cereus].	30.61	539	342	18	7	530	4	525	7e-54	206
rs:WP_017170471	DNA topoisomerase [Xanthomonas axonopodis].	28.49	551	354	13	7	530	4	541	7e-54	206
rs:WP_045178387	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	7e-54	206
sp:TOP3_STAHJ	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	27.12	612	383	19	7	598	5	573	7e-54	206
rs:WP_000838484	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	7e-54	206
rs:WP_024562713	DNA topoisomerase III, partial [Cronobacter turicensis].	28.74	515	336	13	56	552	1	502	7e-54	204
rs:WP_031833188	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	7e-54	206
rs:WP_045660704	DNA topoisomerase [Clostridiaceae bacterium BRH_c20a].	29.76	588	367	17	8	558	7	585	7e-54	205
rs:WP_018589388	DNA topoisomerase III [Terrisporobacter glycolicus].	29.40	568	344	16	7	559	6	531	7e-54	206
rs:WP_031893696	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	7e-54	206
rs:WP_000766774	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	31.17	539	339	19	7	530	4	525	7e-54	206
rs:WP_023627631	hypothetical protein [Bacillus sp. 17376].	30.04	556	350	17	7	544	4	538	7e-54	206
rs:WP_002345924	DNA topoisomerase III [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	7e-54	206
rs:WP_017097009	hypothetical protein [Vibrio tasmaniensis].	31.66	559	334	16	4	532	1	541	8e-54	206
tr:A0A061Q3G6_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.65	562	372	11	8	549	5	557	8e-54	206
rs:WP_028076707	DNA topoisomerase III [Solirubrobacterales bacterium URHD0059].	27.45	572	372	17	5	550	4	558	8e-54	206
rs:WP_031669330	hypothetical protein [Listeria monocytogenes].	30.18	570	333	19	7	544	5	541	8e-54	206
rs:WP_000766744	DNA topoisomerase III [Bacillus cereus].	31.17	539	339	19	7	530	4	525	8e-54	206
rs:WP_038812454	topoisomerase [Staphylococcus epidermidis].	27.06	632	381	16	7	606	5	588	8e-54	206
tr:D4VUU6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.02	579	375	15	5	563	3	565	8e-54	204
rs:WP_005469461	DNA topoisomerase III [Porphyromonas catoniae].	26.95	564	365	14	7	546	2	542	8e-54	206
rs:WP_031901836	DNA topoisomerase 3 [Staphylococcus aureus].	28.17	568	360	18	7	559	5	539	8e-54	206
rs:WP_007349726	DNA topoisomerase III [Marinobacter sp. ELB17].	28.40	567	375	14	8	552	5	562	8e-54	206
rs:WP_017108524	hypothetical protein [Vibrio tasmaniensis].	31.66	559	334	16	4	532	1	541	8e-54	206
rs:WP_025752003	DNA topoisomerase III [Bacillus flexus].	29.18	562	347	17	7	548	4	534	9e-54	206
rs:WP_000766742	DNA topoisomerase III [Bacillus cereus].	30.34	557	347	19	7	548	4	534	9e-54	206
rs:WP_014471442	DNA topoisomerase III [Bacillus amyloliquefaciens].	29.90	572	324	19	3	539	2	531	9e-54	206
rs:WP_016147854	DNA topoisomerase III [Butyricicoccus pullicaecorum].	29.87	549	326	17	7	539	4	509	9e-54	206
rs:WP_041101310	DNA topoisomerase III, partial [Sulfuritalea hydrogenivorans].	30.23	569	352	19	7	550	5	553	9e-54	207
rs:WP_036606074	DNA topoisomerase III [Paenibacillus sp. FSL H7-689].	29.42	571	330	19	5	550	3	525	9e-54	206
rs:WP_000766741	DNA topoisomerase III [Bacillus thuringiensis].	30.34	557	347	19	7	548	4	534	9e-54	206
rs:WP_016114467	DNA topoisomerase III [Bacillus cereus].	28.97	542	353	18	4	530	2	526	9e-54	206
rs:WP_000766759	DNA topoisomerase III [Bacillus cereus].	30.24	539	344	19	7	530	4	525	9e-54	206
rs:WP_037558586	DNA topoisomerase III [Staphylococcus haemolyticus].	27.24	613	381	20	7	598	5	573	9e-54	206
rs:WP_034750165	DNA topoisomerase III [Bacillus wakoensis].	27.95	551	357	14	5	539	4	530	9e-54	206
rs:WP_031870002	DNA topoisomerase III [Staphylococcus aureus].	28.17	568	360	18	7	559	5	539	9e-54	206
rs:WP_000766755	DNA topoisomerase III [Bacillus cereus].	30.43	539	343	18	7	530	4	525	9e-54	206
rs:WP_033859739	DNA topoisomerase III [Staphylococcus aureus].	28.17	568	360	18	7	559	5	539	1e-53	206
rs:WP_019002781	hypothetical protein [Succinimonas amylolytica].	28.62	587	367	17	7	563	4	568	1e-53	206
rs:WP_002337695	DNA topoisomerase III [Enterococcus faecium].	29.19	579	374	15	5	563	3	565	1e-53	206
rs:WP_002461797	DNA topoisomerase III [Staphylococcus simiae].	29.19	620	383	21	7	606	5	588	1e-53	206
rs:WP_016763797	DNA topoisomerase III [Bacillus megaterium].	29.18	562	347	17	7	548	4	534	1e-53	206
rs:WP_034652787	DNA topoisomerase III [Bacillus megaterium].	29.18	562	347	17	7	548	4	534	1e-53	206
rs:WP_013082807	DNA topoisomerase III [Bacillus megaterium].	29.18	562	347	17	7	548	4	534	1e-53	206
rs:WP_000766754	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.43	539	343	18	7	530	4	525	1e-53	206
rs:WP_000766740	DNA topoisomerase III [Bacillus thuringiensis].	30.61	539	342	18	7	530	4	525	1e-53	206
rs:WP_021426535	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.62	557	325	17	7	544	6	514	1e-53	206
rs:WP_013855353	DNA topoisomerase III [Lactobacillus kefiranofaciens].	29.07	633	379	21	5	603	3	599	1e-53	206
rs:WP_034103981	DNA topoisomerase III [Desulfotomaculum sp. BICA1-6].	26.71	584	365	20	7	563	5	552	1e-53	205
rs:WP_025479564	DNA topoisomerase [Enterococcus faecium].	29.85	583	367	18	5	563	3	567	1e-53	206
rs:WP_006427725	DNA topoisomerase III [Dorea longicatena].	27.96	583	350	16	7	539	5	567	1e-53	206
rs:WP_000766784	DNA topoisomerase III [Bacillus cereus].	30.43	539	343	18	7	530	4	525	1e-53	206
rs:WP_000766732	DNA topoisomerase III [Bacillus thuringiensis].	30.88	557	344	20	7	548	4	534	1e-53	206
rs:WP_045029767	DNA topoisomerase III [Draconibacterium sp. JN14CK-3].	28.08	609	383	20	7	597	2	573	1e-53	206
rs:WP_043981980	DNA topoisomerase III [Bacillus aryabhattai].	29.36	562	346	17	7	548	4	534	1e-53	206
rs:WP_000114567	DNA topoisomerase III [Bacillus thuringiensis].	29.14	580	354	19	7	556	5	557	1e-53	206
rs:WP_002509280	DNA topoisomerase III [Staphylococcus arlettae].	28.95	570	354	18	7	559	5	540	1e-53	205
tr:W0S9R8_9RHOO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.23	569	352	19	7	550	5	553	1e-53	207
rs:WP_002496109	DNA topoisomerase III [Staphylococcus epidermidis].	27.27	627	386	16	7	606	5	588	1e-53	205
rs:WP_027391237	DNA topoisomerase III [Aquimarina latercula].	30.14	554	341	17	8	550	5	523	1e-53	206
rs:WP_018963384	hypothetical protein [Coprothermobacter platensis].	30.18	550	341	17	7	550	5	517	1e-53	205
rs:WP_031882918	DNA topoisomerase III [Staphylococcus aureus].	28.17	568	360	18	7	559	5	539	1e-53	205
rs:WP_010726512	DNA topoisomerase III [Enterococcus faecium].	30.03	586	362	19	5	563	3	567	1e-53	206
rs:WP_045509010	DNA topoisomerase III [Bacillus amyloliquefaciens].	29.72	572	325	19	3	539	2	531	1e-53	206
rs:WP_021846108	DNA topoisomerase [Blautia hydrogenotrophica CAG:147].	29.15	566	345	17	7	548	5	538	1e-53	206
rs:WP_021458968	DNA topoisomerase III [Staphylococcus sp. EGD-HP3].	28.95	570	354	18	7	559	5	540	1e-53	205
rs:WP_029550108	DNA topoisomerase III [Staphylococcus aureus].	28.17	568	360	18	7	559	5	539	1e-53	205
rs:WP_016132735	DNA topoisomerase III [Bacillus cereus].	29.13	539	350	18	7	530	6	527	1e-53	205
rs:WP_005426888	DNA topoisomerase III [[Ruminococcus] obeum].	28.02	546	348	14	7	532	5	525	1e-53	206
rs:WP_007845581	MULTISPECIES: DNA topoisomerase [Chryseobacterium].	28.55	571	351	16	7	552	4	542	1e-53	205
tr:C3GTB4_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.14	580	354	19	7	556	11	563	1e-53	205
rs:WP_013106257	DNA topoisomerase III [Thiomonas arsenitoxydans].	29.49	546	345	15	7	536	4	525	1e-53	205
tr:A0A0A3VX20_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.61	539	342	18	7	530	4	525	1e-53	205
rs:WP_021408466	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.62	557	325	17	7	544	6	514	1e-53	205
rs:WP_000838481	DNA topoisomerase III [Staphylococcus aureus].	28.06	588	369	19	7	573	5	559	1e-53	205
rs:WP_037549759	DNA topoisomerase III [Staphylococcus haemolyticus].	27.12	612	383	19	7	598	5	573	1e-53	205
rs:WP_009890468	DNA topoisomerase III [Peptoclostridium difficile].	29.62	557	325	17	7	544	6	514	1e-53	205
rs:WP_022059536	DNA topoisomerase [Coprococcus eutactus CAG:665].	28.31	590	367	19	8	554	6	582	1e-53	205
rs:WP_017553244	DNA topoisomerase III [Bacillus coagulans].	29.49	546	347	18	3	530	2	527	1e-53	205
rs:WP_008459746	DNA topoisomerase [Lactobacillus equicursoris].	30.37	573	352	18	5	555	3	550	1e-53	205
rs:WP_012662275	DNA topoisomerase III [Campylobacter lari].	27.76	580	376	14	8	559	5	569	1e-53	205
rs:WP_002318121	DNA topoisomerase [Enterococcus faecium].	29.33	583	370	17	5	563	3	567	1e-53	205
rs:WP_013859245	DNA topoisomerase III [Bacillus coagulans].	29.49	546	347	18	3	530	2	527	1e-53	205
rs:WP_032732402	DNA topoisomerase III, partial [Bacillus subtilis].	28.87	568	346	18	5	544	3	540	1e-53	204
rs:WP_034264488	DNA topoisomerase III [Bacillus sp. Aph1].	29.41	544	342	16	7	530	4	525	1e-53	205
rs:WP_002422089	DNA topoisomerase III, partial [Yersinia pestis].	27.07	532	361	12	7	522	4	524	1e-53	202
rs:WP_009904388	DNA topoisomerase III [Peptoclostridium difficile].	29.62	557	325	17	7	544	6	514	1e-53	205
rs:WP_014269454	DNA topoisomerase III [Sphaerochaeta pleomorpha].	28.08	577	364	16	7	560	5	553	1e-53	206
tr:W1EZD8_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.21	507	332	11	4	489	1	496	1e-53	201
rs:WP_029141629	DNA topoisomerase III [Bacillus coagulans].	29.49	546	347	18	3	530	2	527	2e-53	205
rs:WP_000766731	DNA topoisomerase III [Bacillus cereus].	30.43	539	343	18	7	530	4	525	2e-53	205
rs:WP_016099578	DNA topoisomerase III [Bacillus cereus].	29.81	577	351	18	7	555	5	555	2e-53	205
rs:WP_031763953	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	2e-53	205
tr:D3LJR4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.33	583	370	17	5	563	4	568	2e-53	205
rs:WP_031905536	DNA topoisomerase 3 [Staphylococcus aureus].	28.17	568	360	18	7	559	5	539	2e-53	205
rs:WP_003033547	MULTISPECIES: DNA topoisomerase III [Bacteria].	30.20	543	324	18	7	539	4	501	2e-53	203
rs:WP_000766781	DNA topoisomerase III [Bacillus cereus].	30.24	539	344	18	7	530	4	525	2e-53	205
rs:WP_031785230	DNA topoisomerase 3 [Staphylococcus aureus].	28.17	568	360	18	7	559	5	539	2e-53	205
rs:WP_004822267	DNA topoisomerase III [Peptoniphilus indolicus].	29.93	548	327	19	7	546	6	504	2e-53	205
rs:WP_002335043	DNA topoisomerase III [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	2e-53	205
rs:WP_038684866	hypothetical protein, partial [Rubrobacter radiotolerans].	28.65	555	360	17	7	544	4	539	2e-53	205
rs:WP_013578458	DNA topoisomerase III [Granulicella tundricola].	29.59	588	356	20	4	563	1	558	2e-53	205
rs:WP_011722358	MULTISPECIES: DNA topoisomerase III [Clostridium].	29.63	567	342	21	8	532	7	558	2e-53	205
rs:WP_029714564	DNA topoisomerase III [Bacillus sp. JGI 001006-L10].	29.18	562	347	17	7	548	4	534	2e-53	205
rs:WP_000766777	DNA topoisomerase III [Bacillus cereus].	30.43	539	343	18	7	530	4	525	2e-53	205
rs:WP_028548262	DNA topoisomerase III [Paenibacillus sp. UNC451MF].	29.42	588	339	17	7	563	5	547	2e-53	205
rs:WP_002489667	DNA topoisomerase 3 [Staphylococcus epidermidis].	27.27	627	386	16	7	606	5	588	2e-53	205
rs:WP_010348782	DNA topoisomerase III [Paenibacillus peoriae].	28.15	572	323	18	7	544	5	522	2e-53	205
rs:WP_002498569	DNA topoisomerase III [Staphylococcus epidermidis].	27.06	632	381	16	7	606	5	588	2e-53	205
rs:WP_042346581	DNA topoisomerase [Bacillus sp. G2(2012b)].	28.50	621	395	19	3	601	2	595	2e-53	205
tr:W7Z0Q0_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.31	563	352	16	3	548	2	535	2e-53	205
rs:WP_047152889	DNA topoisomerase III [Aneurinibacillus tyrosinisolvens].	27.92	566	344	15	5	550	3	524	2e-53	205
rs:WP_045524206	DNA topoisomerase III [Bacillus niacini].	28.85	558	355	15	7	544	4	539	2e-53	205
rs:WP_004849107	DNA topoisomerase III [Coprococcus eutactus].	28.31	590	367	19	8	554	6	582	2e-53	204
rs:WP_044599622	DNA topoisomerase III [Campylobacter peloridis].	27.88	581	374	16	8	559	5	569	2e-53	204
rs:WP_045289425	DNA topoisomerase III [Bacillus aryabhattai].	29.18	562	347	17	7	548	4	534	2e-53	205
rs:WP_043715373	hypothetical protein, partial [Symbiobacterium thermophilum].	28.52	568	354	15	1	544	1	540	2e-53	205
rs:WP_013123595	DNA topoisomerase III [Thiomonas intermedia].	29.23	544	341	17	7	531	4	522	2e-53	205
rs:WP_025479791	DNA topoisomerase [Enterococcus faecium].	28.99	583	372	17	5	563	3	567	2e-53	205
tr:A0A023X4M0_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.65	555	360	17	7	544	4	539	2e-53	205
rs:WP_016088351	DNA topoisomerase III [Bacillus cereus].	30.24	539	344	19	7	530	4	525	2e-53	205
rs:WP_035613615	DNA topoisomerase, partial [Lachnospiraceae bacterium COE1].	28.57	602	359	16	7	550	6	594	2e-53	204
rs:WP_002329190	DNA topoisomerase [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	2e-53	205
rs:WP_042969683	DNA topoisomerase III [Bacillus thuringiensis].	30.43	539	343	18	7	530	4	525	2e-53	205
rs:WP_016134173	DNA topoisomerase III [Bacillus cereus].	30.16	557	348	19	7	548	4	534	2e-53	205
rs:WP_043893430	DNA topoisomerase III, partial [Osedax symbiont Rs2].	27.95	601	389	16	8	582	5	587	2e-53	203
rs:WP_033578745	DNA topoisomerase III [Bacillus aryabhattai].	29.41	544	342	16	7	530	4	525	2e-53	205
rs:WP_021364630	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.44	557	326	17	7	544	6	514	2e-53	205
rs:WP_002485898	DNA topoisomerase III [Staphylococcus epidermidis].	27.27	627	386	16	7	606	5	588	2e-53	205
rs:WP_045173686	DNA topoisomerase III [Staphylococcus aureus].	28.35	568	359	18	7	559	5	539	2e-53	205
rs:WP_039111128	DNA topoisomerase III [Flavobacterium sp. KMS].	30.02	553	342	18	8	550	5	522	2e-53	205
rs:WP_010731512	DNA topoisomerase III [Enterococcus faecium].	29.86	586	363	19	5	563	3	567	2e-53	205
rs:WP_014279833	DNA topoisomerase III [Paenibacillus terrae].	28.01	564	333	18	7	544	5	521	2e-53	205
rs:WP_002171395	DNA topoisomerase III [Bacillus cereus].	30.43	539	343	19	7	530	4	525	2e-53	205
rs:WP_038399531	topoisomerase [Staphylococcus epidermidis].	27.27	627	386	16	7	606	5	588	2e-53	205
rs:WP_010829678	DNA topoisomerase III [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	2e-53	205
rs:WP_010728361	DNA topoisomerase III [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	2e-53	205
rs:WP_013172858	DNA topoisomerase III [[Bacillus] selenitireducens].	27.76	562	371	16	7	552	4	546	2e-53	205
rs:WP_000766752	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.98	539	340	19	7	530	4	525	2e-53	205
rs:WP_009558242	DNA topoisomerase [Lactobacillus equicursoris].	30.66	574	349	19	5	555	3	550	2e-53	204
rs:WP_010235392	DNA topoisomerase III [Clostridium arbusti].	29.37	572	347	20	1	548	1	539	2e-53	205
rs:WP_022201063	DNA topoisomerase [Clostridium clostridioforme CAG:132].	28.72	571	346	18	7	548	5	543	2e-53	205
rs:WP_044930836	DNA topoisomerase III [Clostridium sp. M62/1].	29.81	567	334	18	7	557	4	522	2e-53	204
rs:WP_010727770	DNA topoisomerase III [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	2e-53	205
rs:WP_006783117	DNA topoisomerase III [[Clostridium] hathewayi].	28.30	569	351	17	7	548	5	543	2e-53	205
rs:WP_012368885	DNA topoisomerase III [Proteus mirabilis].	30.60	562	354	13	7	543	4	554	2e-53	205
rs:WP_034130836	DNA topoisomerase III [Peptococcaceae bacterium BICA1-8].	28.37	578	360	18	7	559	6	554	2e-53	205
rs:WP_002170059	DNA topoisomerase III [Bacillus cereus].	30.20	553	338	16	4	531	1	530	2e-53	205
tr:A0A0B5WW23_BACCO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.52	542	344	18	7	530	2	523	2e-53	205
rs:WP_019850806	DNA topoisomerase III [Desulfitobacterium sp. PCE1].	30.05	569	347	19	5	539	4	555	2e-53	205
rs:WP_000838477	DNA topoisomerase III [Staphylococcus aureus].	28.17	568	360	18	7	559	5	539	2e-53	204
rs:WP_039810558	DNA topoisomerase III [Jeotgalibacillus sp. D5].	29.62	574	340	18	4	548	2	540	2e-53	204
rs:WP_035286737	DNA topoisomerase III, partial [Brevibacillus massiliensis].	28.65	548	349	16	4	530	1	527	2e-53	203
rs:WP_023523820	DNA topoisomerase III [Enterococcus mundtii].	29.33	583	370	18	5	563	3	567	2e-53	205
rs:WP_025480388	DNA topoisomerase [Enterococcus faecium].	28.99	583	372	17	5	563	3	567	2e-53	205
rs:WP_028413674	DNA topoisomerase III [Bacillus sp. 278922_107].	29.18	562	347	17	7	548	4	534	2e-53	204
rs:WP_017763026	DNA topoisomerase III [Bacillus thuringiensis].	30.43	539	343	18	7	530	4	525	2e-53	204
tr:A0A098ETD9_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.88	554	331	19	7	546	8	512	2e-53	204
rs:WP_031797387	DNA topoisomerase III [Staphylococcus aureus].	28.17	568	360	18	7	559	5	539	2e-53	204
rs:WP_002470665	DNA topoisomerase III [Staphylococcus epidermidis].	27.27	627	386	16	7	606	5	588	2e-53	204
sp:TOP3_STAEQ	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	27.27	627	386	16	7	606	5	588	2e-53	204
rs:WP_038729615	DNA topoisomerase [Burkholderia sp. ABCPW 1].	27.94	587	365	17	7	547	5	579	2e-53	204
rs:WP_022387855	DNA topoisomerase [Ruminococcus obeum CAG:39].	28.02	546	348	14	7	532	5	525	2e-53	204
tr:G4B181_AGGAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.77	494	292	21	7	468	4	479	2e-53	201
rs:WP_040103605	DNA topoisomerase III [Paenibacillus polymyxa].	29.33	549	339	16	7	530	4	528	3e-53	204
rs:WP_020492503	DNA topoisomerase III [Dehalobacter sp. FTH1].	26.66	574	363	16	7	539	6	562	3e-53	205
rs:WP_024636303	DNA topoisomerase [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	3e-53	205
rs:WP_005944631	DNA topoisomerase III [Blautia hydrogenotrophica].	29.15	566	345	17	7	548	5	538	3e-53	204
sp:TOP3_STAES	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	27.27	627	386	16	7	606	5	588	3e-53	204
rs:WP_000766767	DNA topoisomerase III [Bacillus thuringiensis].	30.43	539	343	18	7	530	4	525	3e-53	204
rs:WP_022345006	DNA topoisomerase [Clostridium sp. CAG:299].	27.82	586	352	18	7	548	5	563	3e-53	205
rs:WP_000766782	DNA topoisomerase III [Bacillus thuringiensis].	30.16	557	348	19	7	548	4	534	3e-53	204
rs:WP_023438760	DNA topoisomerase I [Clostridium tetani].	28.55	599	378	20	7	579	5	579	3e-53	204
rs:WP_032078168	DNA topoisomerase III [Clostridium drakei].	29.05	592	366	21	8	554	7	589	3e-53	205
rs:WP_021362717	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.44	557	326	17	7	544	6	514	3e-53	204
rs:WP_025478649	DNA topoisomerase [Enterococcus faecium].	28.99	583	372	17	5	563	3	567	3e-53	204
rs:WP_000766743	DNA topoisomerase III [Bacillus cereus].	30.98	539	340	19	7	530	4	525	3e-53	204
rs:WP_038563885	DNA topoisomerase III [Terribacillus aidingensis].	28.88	547	342	15	5	532	4	522	3e-53	204
rs:WP_044140538	DNA topoisomerase III [Bacillus pumilus].	29.68	566	348	18	3	548	2	537	3e-53	204
rs:WP_023971603	DNA topoisomerase III, partial [Salmonella enterica].	28.26	506	336	13	7	496	4	498	3e-53	201
rs:WP_002188055	DNA topoisomerase III [Bacillus cereus].	30.38	553	337	16	4	531	1	530	3e-53	204
tr:D4CB69_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.16	567	332	19	7	557	21	539	3e-53	204
rs:WP_035331343	DNA topoisomerase III [Bacillus firmus].	28.73	543	347	15	7	530	4	525	3e-53	204
rs:WP_003196873	MULTISPECIES: DNA topoisomerase III [Bacillus].	28.72	564	347	17	7	548	4	534	3e-53	204
rs:WP_038952236	DNA topoisomerase III, partial [Bradyrhizobium japonicum].	27.21	566	358	14	7	550	6	539	3e-53	202
rs:WP_016082039	DNA topoisomerase III [Bacillus cereus].	30.43	539	343	18	7	530	4	525	3e-53	204
rs:WP_002056427	DNA topoisomerase III [Bacillus cereus].	29.52	542	350	18	4	530	2	526	3e-53	204
tr:S4E644_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.02	579	375	15	5	563	20	582	3e-53	204
rs:WP_019721177	DNA topoisomerase III [Bacillus coagulans].	29.49	546	347	18	3	530	2	527	3e-53	204
rs:WP_029442008	DNA topoisomerase III [Bacillus thuringiensis].	30.43	539	343	18	7	530	4	525	3e-53	204
rs:WP_010732632	DNA topoisomerase III [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	3e-53	204
rs:WP_033829617	DNA topoisomerase III [Bacillus sp. KW-12].	27.21	610	404	17	7	597	4	592	3e-53	204
rs:WP_030091797	hypothetical protein, partial [Sphingomonas sp. DC-6].	30.02	563	348	14	3	546	2	537	3e-53	203
rs:WP_016077855	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	30.43	539	343	18	7	530	4	525	3e-53	204
rs:WP_024635188	DNA topoisomerase [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	3e-53	204
rs:WP_032088529	DNA topoisomerase III [Bacillus aquimaris].	27.15	615	405	16	4	599	1	591	3e-53	204
rs:WP_031901756	DNA topoisomerase III [Staphylococcus aureus].	28.17	568	360	18	7	559	5	539	3e-53	204
rs:WP_045926222	DNA topoisomerase III [Bacillus siamensis].	29.72	572	325	19	3	539	2	531	3e-53	204
rs:WP_013739402	DNA topoisomerase III [Sphaerochaeta coccoides].	28.50	621	383	19	7	602	5	589	3e-53	205
rs:WP_000838507	DNA topoisomerase III [Staphylococcus aureus].	28.60	570	355	19	7	559	5	539	4e-53	204
rs:WP_002494147	DNA topoisomerase III [Staphylococcus epidermidis].	27.44	634	376	17	7	606	5	588	4e-53	204
rs:WP_044736728	DNA topoisomerase III [Geobacillus kaustophilus].	27.99	561	364	15	4	544	1	541	4e-53	204
rs:WP_033125471	DNA topoisomerase III [Eubacterium sp. ER2].	28.06	563	350	16	7	544	5	537	4e-53	204
rs:WP_017706786	DNA topoisomerase III, partial [Pseudomonas syringae].	33.07	387	242	9	7	388	4	378	4e-53	197
rs:WP_036880865	DNA topoisomerase III [Porphyromonas sp. COT-239 OH1446].	28.50	593	351	20	7	563	2	557	4e-53	203
rs:WP_021377959	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.41	561	321	17	7	544	6	514	4e-53	204
rs:WP_032824678	topoisomerase I [Oenococcus oeni].	30.77	624	381	22	5	603	3	600	4e-53	204
rs:WP_021421634	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.44	557	326	17	7	544	6	514	4e-53	204
rs:WP_013274289	DNA topoisomerase III [[Clostridium] saccharolyticum].	29.43	547	334	16	7	539	4	512	4e-53	204
tr:L8PRE1_BACIU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.87	568	346	18	5	544	33	570	4e-53	203
rs:WP_044816425	DNA topoisomerase III, partial [Escherichia coli].	29.61	466	305	11	103	552	2	460	4e-53	201
rs:WP_029440902	DNA topoisomerase III [Bacillus thuringiensis].	30.98	539	340	19	7	530	4	525	4e-53	204
rs:WP_000114568	DNA topoisomerase III [Bacillus thuringiensis].	29.04	582	352	20	7	556	5	557	4e-53	204
rs:WP_038810916	DNA topoisomerase III, partial [Peptoclostridium difficile].	29.41	561	321	17	7	544	6	514	4e-53	204
rs:WP_002477639	DNA topoisomerase 3 [Staphylococcus epidermidis].	27.06	632	381	16	7	606	5	588	4e-53	204
rs:WP_013351049	MULTISPECIES: DNA topoisomerase III [Bacillus subtilis group].	29.72	572	325	19	3	539	2	531	4e-53	204
rs:WP_039272353	DNA topoisomerase III [Paenibacillus polymyxa].	27.45	572	327	16	7	544	5	522	4e-53	204
rs:WP_044145021	DNA topoisomerase [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	4e-53	204
rs:WP_043935007	MULTISPECIES: DNA topoisomerase III [Bacillus].	30.43	539	343	18	7	530	4	525	4e-53	204
rs:WP_034674086	DNA topoisomerase III, partial [Bacillus niacini].	28.52	561	353	16	7	544	4	539	4e-53	204
rs:WP_044146630	DNA topoisomerase [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	4e-53	204
rs:WP_038398917	DNA topoisomerase [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	4e-53	204
rs:WP_029485280	DNA topoisomerase [Enterococcus faecium].	28.97	580	374	16	5	563	3	565	4e-53	204
rs:WP_039842175	DNA topoisomerase III [Vibrio owensii].	28.72	564	370	12	8	549	5	558	5e-53	204
rs:WP_044053591	DNA topoisomerase III [Bacillus subtilis].	29.84	573	324	20	3	539	2	532	5e-53	204
rs:WP_006708809	DNA topoisomerase III [Serratia symbiotica].	27.97	547	355	14	7	531	4	533	5e-53	202
rs:WP_002345093	DNA topoisomerase III [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	5e-53	204
rs:WP_043867614	DNA topoisomerase III [Bacillus amyloliquefaciens].	29.72	572	325	19	3	539	2	531	5e-53	204
rs:WP_025478277	DNA topoisomerase [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	5e-53	204
rs:WP_040107074	DNA topoisomerase [Azotobacter chroococcum].	28.28	548	356	12	7	530	4	538	5e-53	204
rs:WP_017690704	DNA topoisomerase III [Paenibacillus sp. PAMC 26794].	29.93	588	335	21	5	563	3	542	5e-53	204
rs:WP_002319742	DNA topoisomerase [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	5e-53	204
rs:WP_025477051	DNA topoisomerase [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	5e-53	204
rs:WP_000766756	DNA topoisomerase III [Bacillus cereus].	30.24	539	344	18	7	530	4	525	5e-53	204
tr:Q67NT6_SYMTH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.52	568	354	15	1	544	1	540	5e-53	204
rs:WP_014460501	DNA topoisomerase III [Bacillus megaterium].	29.00	562	348	17	7	548	4	534	5e-53	204
tr:J7CXS9_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.02	579	375	15	5	563	20	582	5e-53	204
rs:WP_022618510	DNA topoisomerase III [Peptoclostridium difficile].	29.41	561	321	17	7	544	6	514	5e-53	203
rs:WP_027130404	DNA topoisomerase III [Gemella cuniculi].	29.13	563	329	17	5	546	3	516	5e-53	203
rs:WP_011244861	DNA topoisomerase [Bacillus thuringiensis].	29.04	582	352	20	7	556	11	563	5e-53	204
rs:WP_043199706	DNA topoisomerase III [Bradyrhizobium sp. URHA0002].	28.42	549	336	16	7	530	6	522	5e-53	204
tr:A0NKA9_OENOE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.77	624	381	22	5	603	10	607	5e-53	204
rs:WP_024720230	DNA topoisomerase III [Bacillus pumilus].	29.15	566	351	18	3	548	2	537	5e-53	204
rs:WP_039117708	DNA topoisomerase III [Flavobacterium sp. JRM].	29.84	553	343	18	8	550	5	522	5e-53	204
rs:WP_002846237	DNA topoisomerase III [Peptostreptococcus anaerobius].	29.84	553	313	18	7	539	4	501	6e-53	201
rs:WP_021366949	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.41	561	321	17	7	544	6	514	6e-53	203
rs:WP_000779860	DNA topoisomerase III [Streptococcus agalactiae].	30.20	543	324	18	7	539	4	501	6e-53	201
rs:WP_023607195	DNA topoisomerase III, partial [Staphylococcus epidermidis].	28.93	598	385	18	7	583	5	583	6e-53	201
rs:WP_046472782	DNA topoisomerase III [Staphylococcus aureus].	27.99	568	361	18	7	559	5	539	6e-53	203
rs:WP_012008960	DNA topoisomerase III [Bacillus pumilus].	29.33	566	350	18	3	548	2	537	6e-53	203
rs:WP_042985232	DNA topoisomerase III [Bacillus mycoides].	30.20	553	338	16	4	531	1	530	6e-53	203
rs:WP_040214331	DNA topoisomerase III [Clostridium sp. MS1].	28.75	567	356	17	3	550	2	539	6e-53	203
tr:J8ZXU3_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.84	579	376	15	5	563	20	582	6e-53	204
rs:WP_029055860	DNA topoisomerase III [Staphylococcus sp. URHA0057].	27.47	597	388	16	7	590	5	569	6e-53	203
rs:WP_035703807	DNA topoisomerase III [Bacillus altitudinis].	29.15	566	351	18	3	548	2	537	6e-53	203
rs:WP_002494670	DNA topoisomerase III [Staphylococcus epidermidis].	27.11	627	387	16	7	606	5	588	6e-53	203
rs:WP_002324101	DNA topoisomerase III [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	6e-53	204
rs:WP_021360748	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.66	563	317	18	7	544	6	514	6e-53	203
rs:WP_027625981	DNA topoisomerase III [Clostridium lundense].	29.46	594	360	22	8	554	7	588	6e-53	204
rs:WP_039869614	DNA topoisomerase III [Paenibacillus sp. FSL R7-0273].	29.06	561	332	16	7	544	5	522	6e-53	203
rs:WP_032822570	topoisomerase I [Oenococcus oeni].	30.77	624	381	22	5	603	3	600	7e-53	203
rs:WP_020616882	DNA topoisomerase III [Paenibacillus daejeonensis].	27.73	631	367	21	7	604	5	579	7e-53	203
rs:WP_009332651	DNA topoisomerase III [Bacillus sp. 2_A_57_CT2].	28.07	538	357	13	7	530	4	525	7e-53	203
rs:WP_003440272	DNA topoisomerase III [Peptoclostridium difficile].	29.41	561	321	17	7	544	6	514	7e-53	203
tr:C2HAZ4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.02	579	375	15	5	563	20	582	7e-53	204
rs:WP_000838491	DNA topoisomerase 3 [Staphylococcus aureus].	27.99	568	361	18	7	559	5	539	7e-53	203
rs:WP_035288127	DNA topoisomerase III [Clostridium sp. KNHs214].	30.24	572	339	21	8	532	7	565	7e-53	204
rs:WP_004165034	DNA topoisomerase [Oenococcus oeni].	30.77	624	381	22	5	603	3	600	7e-53	203
rs:WP_041966979	DNA topoisomerase III [Bacillus selenatarsenatis].	29.87	559	348	19	7	544	4	539	7e-53	203
rs:WP_010527810	DNA topoisomerase III [Thermophagus xiamenensis].	29.34	559	349	18	4	550	1	525	7e-53	204
rs:WP_010777139	DNA topoisomerase III [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	7e-53	203
tr:B4D958_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.10	567	355	19	5	548	3	545	7e-53	202
rs:WP_007808804	DNA topoisomerase III [Flavobacterium sp. CF136].	30.00	550	346	17	8	550	5	522	7e-53	204
rs:WP_021365580	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.41	561	321	17	7	544	6	514	7e-53	203
rs:WP_034638379	DNA topoisomerase III, partial [Bacillus manliponensis].	29.16	535	339	19	7	522	4	517	7e-53	200
rs:WP_029516042	DNA topoisomerase III [Paenibacillus polymyxa].	27.19	570	331	15	7	544	5	522	7e-53	203
rs:WP_003423232	DNA topoisomerase III [Peptoclostridium difficile].	29.08	557	328	17	7	544	6	514	7e-53	203
rs:WP_047211640	DNA topoisomerase III [Staphylococcus aureus].	27.99	568	361	18	7	559	5	539	7e-53	203
rs:WP_002344214	DNA topoisomerase III [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	7e-53	203
rs:WP_021390633	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.41	561	321	17	7	544	6	514	8e-53	203
rs:WP_031453405	DNA topoisomerase III [Flavobacterium chungangense].	30.38	553	340	18	8	550	5	522	8e-53	203
rs:WP_041847283	DNA topoisomerase III [Bacillus thermoamylovorans].	30.74	579	328	24	1	544	1	541	8e-53	203
rs:WP_035619101	DNA topoisomerase III [Flavobacterium hydatis].	29.84	553	343	18	8	550	5	522	8e-53	203
rs:WP_025477253	DNA topoisomerase [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	8e-53	203
rs:WP_025719153	DNA topoisomerase III [Paenibacillus sp. 1-18].	27.53	574	324	19	7	544	5	522	8e-53	203
rs:WP_021402614	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.44	557	326	17	7	544	6	514	8e-53	203
rs:WP_022628548	DNA topoisomerase III [Bacillus marmarensis].	29.25	588	371	19	39	603	38	603	8e-53	203
rs:WP_029341148	DNA topoisomerase III [Exiguobacterium acetylicum].	29.23	496	323	12	43	530	42	517	9e-53	203
rs:WP_021359429	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.41	561	321	17	7	544	6	514	9e-53	203
rs:WP_040058895	hypothetical protein [Bacillus sp. REN51N].	28.57	574	367	18	5	557	3	554	9e-53	204
rs:WP_015445012	DNA topoisomerase [Legionella pneumophila].	27.93	623	402	15	8	599	5	611	9e-53	202
rs:WP_016729072	DNA topoisomerase III [Peptoclostridium difficile].	29.41	561	321	17	7	544	6	514	9e-53	203
rs:WP_008408467	DNA topoisomerase III [Bacillus isronensis].	27.58	631	386	21	7	603	4	597	9e-53	203
rs:WP_021254751	DNA topoisomerase III [Paenibacillus alvei].	28.13	583	340	20	7	557	5	540	9e-53	203
rs:WP_041137912	DNA topoisomerase III [Clostridiaceae bacterium GM1].	28.85	558	357	15	5	548	4	535	9e-53	203
rs:WP_002335350	DNA topoisomerase III [Enterococcus faecium].	29.69	586	364	19	5	563	3	567	9e-53	203
rs:WP_009905839	DNA topoisomerase III [Peptoclostridium difficile].	29.08	557	328	17	7	544	6	514	9e-53	202
rs:WP_029283791	DNA topoisomerase III [Bacillus indicus].	29.47	526	333	15	43	550	44	549	9e-53	203
rs:WP_027451300	DNA topoisomerase III [Porphyromonas uenonis].	28.87	568	354	18	7	549	2	544	9e-53	201
rs:WP_021417641	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.41	561	321	17	7	544	6	514	9e-53	202
rs:WP_022412826	DNA topoisomerase [Clostridium sp. CAG:470].	27.29	612	379	17	7	560	6	609	9e-53	202
rs:WP_010776544	DNA topoisomerase III [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	9e-53	203
rs:WP_021370480	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.41	561	321	17	7	544	6	514	9e-53	202
rs:WP_028532117	DNA topoisomerase III [Paenibacillus sp. UNC217MF].	28.13	583	340	20	7	557	5	540	1e-52	203
rs:WP_002343287	DNA topoisomerase III [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	1e-52	203
rs:WP_029567330	DNA topoisomerase III [Bacillus cibi].	29.47	526	333	15	43	550	44	549	1e-52	202
rs:WP_025907666	DNA topoisomerase III [Bacillus flexus].	28.60	549	351	16	4	530	1	530	1e-52	203
rs:WP_035398234	DNA topoisomerase III [Exiguobacterium sp. OS-77].	29.58	497	320	14	43	530	42	517	1e-52	202
rs:WP_002295634	DNA topoisomerase [Enterococcus faecium].	29.69	586	364	19	5	563	3	567	1e-52	203
rs:WP_021413935	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.41	561	321	17	7	544	6	514	1e-52	202
rs:WP_016839134	DNA topoisomerase [Ureibacillus thermosphaericus].	27.96	626	400	19	7	606	4	604	1e-52	203
rs:WP_002192122	DNA topoisomerase III [Bacillus cereus].	30.38	553	337	16	4	531	1	530	1e-52	203
rs:WP_008712616	DNA topoisomerase III [Synergistes sp. 3_1_syn1].	28.29	502	334	10	43	531	39	527	1e-52	202
rs:WP_038809474	DNA topoisomerase [Enterococcus faecium].	29.69	586	364	19	5	563	3	567	1e-52	203
rs:WP_039678617	DNA topoisomerase III [Terrisporobacter othiniensis].	29.66	580	327	20	7	559	6	531	1e-52	202
rs:WP_002486256	DNA topoisomerase III [Staphylococcus epidermidis].	27.33	622	392	15	7	606	5	588	1e-52	202
rs:WP_021394124	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.41	561	321	17	7	544	6	514	1e-52	202
rs:WP_019379736	DNA topoisomerase III [Bacillus oceanisediminis].	28.07	538	357	13	7	530	4	525	1e-52	202
rs:WP_010531156	DNA topoisomerase III [Lentibacillus jeotgali].	26.98	630	396	18	3	602	2	597	1e-52	202
rs:WP_045035034	DNA topoisomerase III [Bacillus invictae].	29.15	566	351	18	3	548	2	537	1e-52	203
rs:WP_009644045	DNA topoisomerase III [Mogibacterium sp. CM50].	28.96	556	322	17	7	543	4	505	1e-52	200
rs:WP_014469759	DNA topoisomerase III [Bacillus amyloliquefaciens].	29.55	572	326	19	3	539	2	531	1e-52	202
tr:H0DFI8_9STAP	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.12	570	353	20	7	559	5	540	1e-52	202
rs:WP_032679819	DNA topoisomerase III [Enterobacter sp. BIDMC 26].	27.96	583	379	14	7	563	5	572	1e-52	203
rs:WP_000115174	DNA topoisomerase III [Bacillus thuringiensis].	28.12	576	362	17	7	555	5	555	1e-52	202
rs:WP_040056402	DNA topoisomerase III [Bacillus sp. REN51N].	28.89	540	329	13	5	535	3	496	1e-52	202
rs:WP_034611031	DNA topoisomerase III [Desulfosporosinus sp. Tol-M].	28.21	592	365	18	5	557	4	574	1e-52	203
rs:WP_002331358	DNA topoisomerase III [Enterococcus faecium].	29.69	586	364	19	5	563	3	567	1e-52	202
rs:WP_028087322	DNA topoisomerase III [Dorea longicatena].	28.08	584	348	17	7	539	5	567	1e-52	203
tr:J9C8M6_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.92	536	349	18	7	527	4	522	1e-52	199
rs:WP_001575003	MULTISPECIES: DNA topoisomerase III [Staphylococcus].	28.95	563	353	15	4	544	1	538	1e-52	202
rs:WP_026591986	DNA topoisomerase III [Bacillus sp. UNC437CL72CviS29].	29.31	539	349	18	7	530	4	525	1e-52	202
tr:R9KJT4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.57	602	359	16	7	550	6	594	1e-52	203
rs:WP_002321299	DNA topoisomerase [Enterococcus faecium].	29.85	583	367	17	5	563	3	567	1e-52	202
rs:WP_042566347	DNA topoisomerase III [Flavobacterium sp. MEB061].	29.64	550	348	17	8	550	5	522	1e-52	203
rs:WP_041487101	DNA topoisomerase III [[Clostridium] sticklandii].	30.03	576	345	20	3	532	2	565	1e-52	202
rs:WP_017152229	DNA topoisomerase III [Bacillus sp. FJAT-13831].	29.26	557	353	19	7	548	4	534	1e-52	202
rs:WP_041508287	DNA topoisomerase III [Bacillus aerophilus].	29.15	566	351	18	3	548	2	537	1e-52	202
rs:WP_018306873	DNA topoisomerase III [Desulfitobacterium hafniense].	29.77	561	353	18	5	539	4	549	1e-52	203
rs:WP_011460046	DNA topoisomerase III [Desulfitobacterium hafniense].	29.34	559	358	16	5	539	4	549	1e-52	203
rs:WP_042983184	DNA topoisomerase III [Bacillus mycoides].	29.14	556	355	17	7	548	4	534	1e-52	202
tr:T4JS35_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.85	583	367	17	5	563	3	567	1e-52	202
rs:WP_025150038	DNA topoisomerase III [Bacillus sp. H1a].	29.50	539	348	18	7	530	4	525	1e-52	202
rs:WP_007061961	DNA topoisomerase III [Clostridium carboxidivorans].	29.39	592	364	21	8	554	7	589	1e-52	203
rs:WP_022777123	DNA topoisomerase [Butyrivibrio sp. AE3009].	28.57	567	354	18	7	532	6	562	1e-52	205
rs:WP_016853417	DNA topoisomerase [Enterococcus faecium].	29.16	583	371	17	5	563	3	567	1e-52	202
rs:WP_010778097	DNA topoisomerase III [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	1e-52	202
rs:WP_002474079	DNA topoisomerase III [Staphylococcus epidermidis].	27.16	626	388	16	7	606	5	588	1e-52	202
tr:E4IYX6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.85	583	367	17	5	563	4	568	1e-52	202
rs:WP_037571267	DNA topoisomerase III [Staphylococcus aureus].	26.96	612	384	19	7	598	5	573	1e-52	202
rs:WP_017465080	DNA topoisomerase III [Staphylococcus epidermidis].	26.90	632	382	16	7	606	5	588	1e-52	202
rs:WP_002299737	DNA topoisomerase [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	1e-52	202
rs:WP_035546994	DNA topoisomerase III [Halobacillus sp. BBL2006].	29.30	570	346	17	7	548	6	546	1e-52	202
rs:WP_041073026	DNA topoisomerase III [Bacillus sp. OxB-1].	28.42	556	359	17	3	544	2	532	2e-52	202
rs:WP_002489011	DNA topoisomerase III [Staphylococcus epidermidis].	27.11	627	387	16	7	606	5	588	2e-52	202
rs:WP_004614870	DNA topoisomerase III [Tyzzerella nexilis].	28.73	550	339	19	7	532	5	525	2e-52	202
rs:WP_022171745	DNA topoisomerase [Blautia sp. CAG:52].	28.02	571	345	17	5	544	3	538	2e-52	202
rs:WP_012959749	DNA topoisomerase III [Bacillus pseudofirmus].	29.28	584	368	19	43	603	42	603	2e-52	202
rs:WP_002318768	DNA topoisomerase [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	2e-52	202
rs:WP_014794498	DNA topoisomerase III [Desulfitobacterium dehalogenans].	29.58	568	351	19	5	539	4	555	2e-52	202
rs:WP_042172682	DNA topoisomerase III [Paenibacillus sp. FSL R7-0331].	29.41	561	330	17	7	544	5	522	2e-52	202
rs:WP_025476753	DNA topoisomerase [Enterococcus faecium].	29.19	579	374	16	5	563	3	565	2e-52	202
rs:WP_010287696	DNA topoisomerase III [Kurthia massiliensis].	27.86	560	373	14	4	550	1	542	2e-52	202
rs:WP_039107208	DNA topoisomerase III [Flavobacterium sp. AED].	30.02	553	342	18	8	550	5	522	2e-52	202
rs:WP_018753683	DNA topoisomerase III [Paenibacillus sanguinis].	28.20	578	341	19	7	559	5	533	2e-52	202
rs:WP_011998820	DNA topoisomerase III [Vibrio campbellii].	28.14	565	372	12	8	549	5	558	2e-52	202
rs:WP_002299813	DNA topoisomerase [Enterococcus faecium].	29.52	586	365	19	5	563	3	567	2e-52	202
rs:WP_047185807	DNA topoisomerase III, partial [Bacilli bacterium VT-13-104].	30.09	565	347	17	7	548	5	544	2e-52	201
rs:WP_010193780	DNA topoisomerase III [Bacillus sp. m3-13].	28.60	549	345	18	7	530	4	530	2e-52	202
rs:WP_043859178	DNA topoisomerase III, partial [Bacillus subtilis].	28.67	565	351	17	5	544	3	540	2e-52	201
rs:WP_007894717	MULTISPECIES: DNA topoisomerase III [Firmicutes].	29.84	553	313	19	7	539	4	501	2e-52	200
rs:WP_005812716	DNA topoisomerase III [Desulfitobacterium hafniense].	29.59	561	354	18	5	539	4	549	2e-52	202
rs:WP_025675355	DNA topoisomerase III [Paenibacillus polymyxa].	28.09	566	331	20	7	544	5	522	2e-52	202
rs:WP_013369460	DNA topoisomerase III [Paenibacillus polymyxa].	28.27	566	330	21	7	544	5	522	2e-52	202
rs:WP_002336984	DNA topoisomerase III [Enterococcus faecium].	29.02	579	375	15	5	563	3	565	2e-52	202
rs:WP_043902904	DNA topoisomerase [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	2e-52	202
tr:W1WMJ5_9ZZZZ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ETJ17674.1};	29.43	547	338	15	7	544	6	513	2e-52	202
rs:WP_012024355	DNA topoisomerase III [Flavobacterium johnsoniae].	30.27	555	338	19	8	550	5	522	2e-52	202
rs:WP_000779857	DNA topoisomerase III [Streptococcus agalactiae].	29.84	553	313	18	7	539	4	501	2e-52	199
rs:WP_015944491	DNA topoisomerase III [Desulfitobacterium hafniense].	29.59	561	354	18	5	539	4	549	2e-52	202
rs:WP_007364773	DNA topoisomerase III [Porphyromonas uenonis].	28.70	568	355	18	7	549	2	544	2e-52	200
rs:WP_002320569	DNA topoisomerase [Enterococcus faecium].	29.86	586	363	19	5	563	3	567	2e-52	202
rs:WP_031836252	DNA topoisomerase III, partial [Staphylococcus aureus].	30.80	552	349	16	5	544	3	533	2e-52	200
rs:WP_020365500	DNA topoisomerase III, partial [Staphylococcus epidermidis].	29.26	598	383	18	7	583	5	583	2e-52	201
rs:WP_000779851	DNA topoisomerase III [Streptococcus agalactiae].	29.84	553	313	19	7	539	4	501	2e-52	199
rs:WP_023987041	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	27.02	570	332	15	7	544	5	522	2e-52	202
rs:WP_045384455	DNA topoisomerase III, partial [Vibrio campbellii].	28.22	567	369	13	8	549	5	558	2e-52	200
rs:WP_040763483	DNA topoisomerase, partial [Sutterella parvirubra].	28.67	579	342	16	7	531	6	567	2e-52	201
rs:WP_002328427	DNA topoisomerase III [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	2e-52	202
rs:WP_002307526	DNA topoisomerase [Enterococcus faecium].	29.69	586	364	19	5	563	3	567	2e-52	202
rs:WP_044715191	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	29.63	567	354	14	7	543	4	555	2e-52	202
tr:L8A4L4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.85	583	367	17	5	563	4	568	2e-52	202
rs:WP_029503852	DNA topoisomerase III [Lachnoclostridium phytofermentans].	28.19	557	357	16	7	548	5	533	2e-52	202
rs:WP_009058926	topoisomerase I [Methylacidiphilum fumariolicum].	28.37	557	366	12	7	544	6	548	2e-52	202
rs:WP_013308786	DNA topoisomerase III [Paenibacillus polymyxa].	27.02	570	332	15	7	544	5	522	2e-52	202
rs:WP_025480603	DNA topoisomerase [Enterococcus faecium].	29.85	583	367	17	5	563	3	567	2e-52	202
rs:WP_021398054	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.41	561	321	17	7	544	6	514	2e-52	201
rs:WP_004331116	DNA topoisomerase III [Porphyromonas asaccharolytica].	28.65	569	354	19	7	549	2	544	2e-52	200
rs:WP_026981915	DNA topoisomerase III [Flavobacterium sp. URHB0058].	29.84	553	343	18	8	550	5	522	2e-52	202
rs:WP_044144889	DNA topoisomerase [Enterococcus faecium].	29.67	583	368	17	5	563	3	567	2e-52	202
rs:WP_045282368	DNA topoisomerase III [Enterobacter sp. 44593].	29.63	567	354	14	7	543	4	555	2e-52	202
rs:WP_028527329	DNA topoisomerase III [Ruminococcus gauvreauii].	27.89	570	351	15	7	548	5	542	2e-52	202
rs:WP_028389296	DNA topoisomerase [Legionella fairfieldensis].	27.69	549	356	13	8	530	5	538	2e-52	201
rs:WP_041197081	DNA topoisomerase [Burkholderia pseudomallei].	27.80	590	362	17	7	547	5	579	2e-52	201
rs:WP_012369865	DNA topoisomerase III [Exiguobacterium sibiricum].	30.71	495	317	13	43	530	42	517	2e-52	201
rs:WP_026828856	DNA topoisomerase III [Exiguobacterium sibiricum].	30.51	495	318	15	43	530	42	517	2e-52	201
rs:WP_000366635	DNA topoisomerase [Streptococcus agalactiae].	28.97	542	332	16	7	539	4	501	2e-52	199
rs:WP_010721414	DNA topoisomerase III [Enterococcus faecium].	29.69	586	364	19	5	563	3	567	2e-52	202
rs:WP_032822357	topoisomerase I [Oenococcus oeni].	30.45	624	383	21	5	603	3	600	3e-52	202
rs:WP_015267562	DNA topoisomerase III [Echinicola vietnamensis].	28.99	545	331	17	8	531	5	514	3e-52	202
tr:A0A0D1IX46_BACIU	SubName: Full=Bacillus subtilis strain HM-66 contig8, whole genome shotgun sequence {ECO:0000313|EMBL:KIU04544.1};	28.57	567	349	18	5	544	3	540	3e-52	201
rs:WP_036176604	DNA topoisomerase III [Lysinibacillus massiliensis].	27.41	540	362	12	7	530	6	531	3e-52	202
tr:E8TUJ8_ALIDB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.82	387	235	10	8	385	5	375	3e-52	195
rs:WP_023966311	DNA topoisomerase III [Paenibacillus sp. JCM 10914].	28.85	572	331	19	7	550	5	528	3e-52	201
rs:WP_040102123	DNA topoisomerase III [Paenibacillus polymyxa].	27.70	574	323	20	7	544	5	522	3e-52	201
rs:WP_002338047	DNA topoisomerase III, partial [Enterococcus faecium].	29.33	583	370	17	5	563	3	567	3e-52	201
rs:WP_002843661	DNA topoisomerase III [Peptostreptococcus anaerobius].	30.02	543	325	18	7	539	4	501	3e-52	199
rs:WP_040427933	DNA topoisomerase III, partial [Acetivibrio cellulolyticus].	29.35	569	357	19	7	559	6	545	3e-52	200
rs:WP_043313879	DNA topoisomerase III, partial [Bacillus cereus].	29.03	534	347	18	7	525	4	520	3e-52	198
rs:WP_000366634	DNA topoisomerase [Streptococcus agalactiae].	28.97	542	332	16	7	539	4	501	3e-52	199
rs:WP_017415987	hypothetical protein [Clostridium tunisiense].	28.59	647	390	24	8	602	7	633	3e-52	202
rs:WP_025206777	DNA topoisomerase III [Bacillus pumilus].	28.80	566	353	18	3	548	2	537	3e-52	201
rs:WP_021666915	DNA topoisomerase III [Porphyromonas sp. oral taxon 278].	29.02	579	336	21	7	546	2	544	3e-52	201
rs:WP_024634928	MULTISPECIES: DNA topoisomerase [Enterococcus].	29.67	583	368	17	5	563	3	567	3e-52	201
tr:L2LKT7_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.67	583	368	17	5	563	4	568	3e-52	201
rs:WP_000838474	DNA topoisomerase III [Staphylococcus aureus].	28.17	568	360	18	7	559	5	539	3e-52	201
rs:WP_014824222	DNA topoisomerase III [Solibacillus silvestris].	27.58	631	386	21	7	603	4	597	3e-52	201
rs:WP_025479080	DNA topoisomerase [Enterococcus faecium].	29.67	583	368	17	5	563	3	567	3e-52	201
rs:WP_005747021	DNA topoisomerase III, partial [Pseudomonas amygdali].	33.60	369	223	10	37	395	16	372	3e-52	194
rs:WP_031789016	DNA topoisomerase III, partial [Staphylococcus aureus].	30.80	552	349	16	5	544	3	533	3e-52	200
rs:WP_035649018	DNA topoisomerase III [Flavobacterium sp. Fl].	30.02	553	342	18	8	550	5	522	3e-52	202
rs:WP_028593686	DNA topoisomerase III [Paenibacillus assamensis].	27.27	572	377	15	45	599	44	593	3e-52	201
rs:WP_003214040	DNA topoisomerase III [Bacillus pumilus].	29.33	566	350	18	3	548	2	537	3e-52	201
rs:WP_025531347	DNA topoisomerase III [[Clostridium] hathewayi].	28.37	571	352	16	7	548	5	547	3e-52	201
rs:WP_017111690	hypothetical protein [Vibrio tasmaniensis].	29.51	576	352	17	7	549	4	558	3e-52	201
tr:V1XDB5_SALMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.92	448	267	13	170	590	8	444	3e-52	198
rs:WP_027320953	DNA topoisomerase III [Bacillus sp. URHB0009].	27.92	616	369	23	7	603	5	564	3e-52	201
rs:WP_002376837	DNA topoisomerase [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	3e-52	201
rs:WP_046342695	DNA topoisomerase III [Bacillus pumilus].	28.98	566	352	18	3	548	2	537	3e-52	201
rs:WP_010860920	DNA topoisomerase III [Lysinibacillus sphaericus].	28.86	544	349	16	7	530	4	529	3e-52	201
rs:WP_005877022	DNA topoisomerase III [Enterococcus durans].	29.52	586	365	19	5	563	3	567	3e-52	201
rs:WP_018671825	DNA topoisomerase III [Brevibacillus laterosporus].	28.59	626	388	19	4	599	1	597	3e-52	201
rs:WP_002198656	DNA topoisomerase III [Bacillus cereus].	28.72	578	356	18	7	555	5	555	3e-52	201
rs:WP_002341526	DNA topoisomerase III [Enterococcus faecium].	28.99	583	372	17	5	563	3	567	3e-52	201
rs:WP_025683568	DNA topoisomerase III [Paenibacillus sp. 1-49].	27.84	564	334	18	7	544	5	521	3e-52	201
rs:WP_036120904	DNA topoisomerase III [Mangrovimonas yunxiaonensis].	28.75	553	349	18	8	550	5	522	3e-52	202
rs:WP_034664011	DNA topoisomerase III [Bacillus pumilus].	29.15	566	351	18	3	548	2	537	3e-52	201
tr:D4MPC5_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.23	585	341	18	7	548	5	559	3e-52	201
rs:WP_035639024	DNA topoisomerase III [Flavobacterium sp. EM1308].	29.48	553	345	18	8	550	5	522	3e-52	202
rs:WP_025480863	DNA topoisomerase [Enterococcus faecium].	29.33	583	370	17	5	563	3	567	3e-52	201
rs:WP_035140704	DNA topoisomerase [Clostridium tetani].	28.12	601	378	20	7	579	5	579	3e-52	201
rs:WP_043902498	DNA topoisomerase [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	3e-52	201
rs:WP_002340635	DNA topoisomerase III [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	3e-52	201
rs:WP_002335714	DNA topoisomerase III [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	3e-52	201
rs:WP_039963133	DNA topoisomerase III [Bacillus stratosphericus].	28.98	566	352	18	3	548	2	537	3e-52	201
rs:WP_041519455	DNA topoisomerase III [Flavobacterium hibernum].	29.48	553	345	18	8	550	5	522	4e-52	201
rs:WP_021259547	DNA topoisomerase III [Paenibacillus alvei].	28.30	583	339	21	7	557	5	540	4e-52	201
tr:Q893I6_CLOTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.01	607	383	20	1	579	1	581	4e-52	201
tr:H3KDU7_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	28.67	579	342	16	7	531	6	567	4e-52	201
rs:WP_002327040	DNA topoisomerase III [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	4e-52	201
rs:WP_014613208	DNA topoisomerase III [Staphylococcus pseudintermedius].	28.19	564	365	15	7	559	6	540	4e-52	201
rs:WP_008347145	MULTISPECIES: DNA topoisomerase III [Bacillus].	28.98	566	352	18	3	548	2	537	4e-52	201
rs:WP_026808919	DNA topoisomerase III [Arenibacter latericius].	29.27	550	351	16	8	550	5	523	4e-52	201
rs:WP_008147589	DNA topoisomerase III [Parabacteroides johnsonii].	28.57	539	338	17	8	531	5	511	4e-52	201
tr:A4NVD0_HAEIF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.90	491	319	12	97	559	2	485	4e-52	199
rs:WP_036125316	MULTISPECIES: DNA topoisomerase III [Lysinibacillus].	28.83	548	345	18	7	530	4	530	4e-52	201
rs:WP_036668403	DNA topoisomerase III [Paenibacillus sp. FSL R5-192].	29.25	588	339	20	5	563	3	542	4e-52	201
rs:WP_007045892	DNA topoisomerase III [Subdoligranulum variabile].	27.86	560	351	15	7	549	4	527	4e-52	201
rs:WP_029268835	DNA topoisomerase III [Flavobacterium sp. KJJ].	29.64	550	348	17	8	550	5	522	4e-52	201
rs:WP_034768980	DNA topoisomerase III [Bacillus thermoamylovorans].	29.26	557	354	16	7	544	4	539	4e-52	201
rs:WP_002602051	DNA topoisomerase III [[Clostridium] hathewayi].	28.20	571	353	16	7	548	5	547	4e-52	201
rs:WP_045424446	DNA topoisomerase III [Vibrio jasicida].	28.37	564	372	12	8	549	5	558	4e-52	201
rs:WP_041072541	DNA topoisomerase III [Bacillus sp. OxB-1].	29.70	559	354	17	7	548	5	541	4e-52	201
rs:WP_045495669	DNA topoisomerase I [Chryseobacterium sp. StRB126].	28.12	576	347	18	7	552	4	542	4e-52	201
rs:WP_042200915	DNA topoisomerase III [Paenibacillus sp. G4].	29.31	563	332	17	5	544	3	522	4e-52	201
rs:WP_029468332	DNA topoisomerase III [Clostridiales bacterium VE202-06].	28.20	571	352	16	7	548	5	546	4e-52	201
rs:WP_022250327	DNA topoisomerase [Clostridium nexile CAG:348].	28.80	552	336	19	7	532	5	525	4e-52	201
rs:WP_046668838	DNA topoisomerase, partial [Enterococcus faecium].	29.39	541	348	14	42	563	6	531	4e-52	201
rs:WP_034324734	DNA topoisomerase III [Bacillus sp. DW5-4].	29.68	566	348	18	3	548	2	537	4e-52	201
rs:WP_017366641	DNA topoisomerase III [Bacillus pumilus].	28.98	566	352	18	3	548	2	537	4e-52	201
tr:A4N2M3_HAEIF	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.44	496	305	16	97	559	1	484	4e-52	199
rs:WP_002327915	DNA topoisomerase III [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	4e-52	201
rs:WP_022272640	DNA topoisomerase [Clostridium sp. CAG:58].	28.20	571	352	19	7	548	5	546	5e-52	201
rs:WP_002484399	DNA topoisomerase III [Staphylococcus epidermidis].	29.10	598	384	18	7	583	5	583	5e-52	201
rs:WP_035109339	DNA topoisomerase [Clostridium tetani].	28.12	601	378	20	7	579	5	579	5e-52	201
rs:WP_018598357	DNA topoisomerase III [Blautia producta].	28.20	571	352	16	7	548	5	546	5e-52	201
rs:WP_020367186	DNA topoisomerase III [Staphylococcus epidermidis].	29.10	598	384	18	7	583	5	583	5e-52	201
rs:WP_010521506	DNA topoisomerase III [Flavobacteriaceae bacterium HQM9].	28.94	539	338	16	8	531	5	513	5e-52	201
rs:WP_041848210	DNA topoisomerase III [Bacillus thermoamylovorans].	29.08	557	355	16	7	544	4	539	5e-52	201
rs:WP_002341464	DNA topoisomerase III [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	5e-52	201
rs:WP_016991292	DNA topoisomerase III [Flavobacterium sp. ACAM 123].	29.82	550	347	17	8	550	5	522	5e-52	201
rs:WP_026901741	DNA topoisomerase III [Peptostreptococcaceae bacterium VA2].	29.62	557	332	18	7	548	6	517	5e-52	201
rs:WP_022112818	DNA topoisomerase [Roseburia intestinalis CAG:13].	27.86	585	368	19	7	550	6	577	5e-52	204
rs:WP_023467640	DNA topoisomerase III [Exiguobacterium sp. MH3].	29.38	497	321	14	43	530	42	517	5e-52	201
rs:WP_031825907	DNA topoisomerase III, partial [Staphylococcus aureus].	30.80	552	349	16	5	544	3	533	5e-52	199
rs:WP_034327551	MULTISPECIES: DNA topoisomerase III [Helicobacter].	27.15	615	390	18	7	590	4	591	5e-52	200
rs:WP_023351307	DNA topoisomerase 3 [Staphylococcus capitis].	26.61	620	399	18	7	606	5	588	5e-52	201
rs:WP_009581364	DNA topoisomerase III [Fulvivirga imtechensis].	29.95	551	319	18	8	531	5	515	5e-52	201
rs:WP_016171196	DNA topoisomerase III [Enterococcus faecium].	28.99	583	372	17	5	563	3	567	5e-52	200
rs:WP_029447957	DNA topoisomerase III [Cellulophaga baltica].	29.04	551	351	16	8	550	5	523	5e-52	201
rs:WP_035390408	DNA topoisomerase III [Bacillus sp. UNC125MFCrub1.1].	28.98	566	352	18	3	548	2	537	5e-52	201
tr:A0A078BN72_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.89	542	337	18	7	531	4	519	5e-52	201
rs:WP_032806200	topoisomerase I [Oenococcus oeni].	30.29	624	384	21	5	603	3	600	5e-52	201
rs:WP_008791950	DNA topoisomerase III [Coprobacillus sp. 8_2_54BFAA].	30.62	552	317	18	7	539	4	508	6e-52	200
rs:WP_031862612	DNA topoisomerase III, partial [Staphylococcus aureus].	30.80	552	349	16	5	544	3	533	6e-52	199
tr:W4RXJ6_9XANT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.43	347	219	6	65	406	13	352	6e-52	193
rs:WP_015056179	DNA topoisomerase III [Staphylococcus aureus].	30.67	551	349	16	5	543	3	532	6e-52	198
rs:WP_035125039	DNA topoisomerase [Clostridium tetani].	28.12	601	378	20	7	579	5	579	6e-52	201
rs:WP_004033898	DNA topoisomerase III [Clostridium sp. ASF356].	30.58	569	338	16	7	552	6	540	6e-52	201
rs:WP_044943098	DNA topoisomerase III [Blautia schinkii].	28.47	562	344	16	7	549	4	526	6e-52	200
rs:WP_040287614	DNA topoisomerase III [Sporosarcina koreensis].	29.72	562	350	21	3	548	11	543	6e-52	201
rs:WP_022072193	DNA topoisomerase III [Clostridium bartlettii CAG:1329].	29.26	598	385	16	4	590	1	571	6e-52	201
rs:WP_034443475	hypothetical protein [Cloacibacillus evryensis].	28.09	502	335	10	43	531	39	527	6e-52	200
rs:WP_045146679	DNA topoisomerase III [Peptoclostridium difficile].	29.08	557	328	17	7	544	6	514	6e-52	200
rs:WP_010777183	DNA topoisomerase III [Enterococcus faecium].	29.69	586	364	19	5	563	3	567	6e-52	201
rs:WP_002686858	DNA topoisomerase III [Treponema denticola].	29.65	570	339	20	1	549	1	529	6e-52	200
rs:WP_041902077	DNA topoisomerase III [Bacillus thermoamylovorans].	29.08	557	355	16	7	544	4	539	6e-52	200
rs:WP_026944559	DNA topoisomerase III [Helicobacter rodentium].	27.10	583	376	17	7	559	4	567	6e-52	201
rs:WP_013606785	DNA topoisomerase III [Sphaerochaeta globosa].	29.81	577	352	18	7	559	5	552	6e-52	201
rs:WP_013271000	DNA topoisomerase III [[Clostridium] saccharolyticum].	28.09	566	353	16	7	548	5	540	6e-52	201
rs:WP_000779852	DNA topoisomerase III [Streptococcus agalactiae].	29.66	553	314	19	7	539	4	501	6e-52	198
rs:WP_039245269	DNA topoisomerase III [Clostridium novyi].	30.04	566	339	17	7	548	6	538	6e-52	201
rs:WP_041091165	DNA topoisomerase III [Bacillus pumilus].	28.98	566	352	18	3	548	2	537	6e-52	201
rs:WP_033142648	DNA topoisomerase III [Blautia producta].	28.22	574	348	17	7	548	5	546	7e-52	201
gpu:CP007601_1368	DNA topoisomerase 3 [Staphylococcus capitis subsp. capitis]	26.61	620	399	17	7	606	5	588	7e-52	200
rs:WP_008396945	DNA topoisomerase III [Clostridium sp. M62/1].	28.72	585	344	17	7	548	5	559	7e-52	201
rs:WP_002340047	DNA topoisomerase III [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	7e-52	201
rs:WP_041189026	DNA topoisomerase [Burkholderia pseudomallei].	27.80	590	362	17	7	547	5	579	7e-52	200
rs:WP_044996546	DNA topoisomerase III [Blautia wexlerae].	27.92	566	354	15	1	549	1	529	7e-52	200
tr:A0A098AZW1_DESHA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.16	559	359	17	5	539	4	549	7e-52	201
rs:WP_012093963	DNA topoisomerase III [Bacillus cytotoxicus].	29.55	538	349	16	7	530	4	525	7e-52	200
rs:WP_026729058	DNA topoisomerase III [Flavobacterium denitrificans].	30.02	553	342	18	8	550	5	522	7e-52	201
rs:WP_011722818	DNA topoisomerase III [Clostridium novyi].	30.04	566	339	17	7	548	6	538	7e-52	200
rs:WP_041964452	DNA topoisomerase III [Bacillus selenatarsenatis].	28.70	561	336	17	7	548	5	520	7e-52	200
rs:WP_022617262	DNA topoisomerase III [Peptoclostridium difficile].	29.08	557	328	17	7	544	6	514	8e-52	200
rs:WP_032119137	DNA topoisomerase III [Clostridium sp. CL-2].	28.64	583	371	19	5	553	4	575	8e-52	199
rs:WP_015256841	DNA topoisomerase III TopB [Klebsiella pneumoniae].	29.63	567	354	14	7	543	4	555	8e-52	201
rs:WP_039226428	DNA topoisomerase III [Clostridium novyi].	30.04	566	339	17	7	548	6	538	8e-52	200
rs:WP_039238656	MULTISPECIES: DNA topoisomerase III [Clostridium].	30.04	566	339	17	7	548	6	538	8e-52	200
rs:WP_003693017	DNA topoisomerase III [Lactobacillus ruminis].	29.38	548	326	20	7	544	5	501	8e-52	200
rs:WP_018705508	hypothetical protein [Bacillus fordii].	29.71	552	327	20	7	544	5	509	8e-52	200
rs:WP_004827735	DNA topoisomerase III [Anaerococcus lactolyticus].	29.66	553	314	19	7	539	4	501	9e-52	198
rs:WP_026694892	DNA topoisomerase [Bacillus kribbensis].	27.59	627	405	19	4	606	2	603	9e-52	200
rs:WP_029162866	DNA topoisomerase III [Clostridium scatologenes].	29.22	592	365	21	8	554	7	589	9e-52	200
rs:WP_045244221	DNA topoisomerase III [Paenibacillus polymyxa].	27.92	566	332	21	7	544	5	522	9e-52	200
rs:WP_022927631	DNA topoisomerase III [Patulibacter americanus].	27.49	633	401	22	5	597	4	618	9e-52	201
rs:WP_015958118	DNA topoisomerase III [Clostridium botulinum].	28.57	609	384	18	7	590	5	587	9e-52	199
rs:WP_003035804	DNA topoisomerase III [Streptococcus anginosus].	28.30	622	367	22	7	606	6	570	9e-52	198
rs:WP_024038076	DNA topoisomerase [Intestinibacter bartlettii].	29.10	598	386	16	4	590	1	571	9e-52	200
rs:WP_022364467	DNA topoisomerase [Clostridium sp. CAG:505].	28.60	570	351	18	5	550	4	541	9e-52	200
rs:WP_004302894	DNA topoisomerase III [Thauera aminoaromatica].	29.86	566	358	20	7	550	6	554	9e-52	201
rs:WP_000366637	MULTISPECIES: DNA topoisomerase [Lactobacillales].	28.78	542	333	16	7	539	4	501	9e-52	198
rs:WP_045657767	DNA topoisomerase III [Clostridiaceae bacterium BRH_c20a].	27.85	578	363	18	7	559	6	554	1e-51	200
rs:WP_003430396	DNA topoisomerase III [Peptoclostridium difficile].	29.08	557	328	17	7	544	6	514	1e-51	200
rs:WP_007287786	DNA topoisomerase III [Intestinibacter bartlettii].	29.10	598	386	16	4	590	1	571	1e-51	200
rs:WP_003029074	MULTISPECIES: DNA topoisomerase III [Streptococcus].	29.52	542	329	17	7	539	4	501	1e-51	198
rs:WP_044359601	DNA topoisomerase III [Staphylococcus microti].	28.55	564	363	14	7	559	5	539	1e-51	200
rs:WP_002823296	DNA topoisomerase [Oenococcus oeni].	30.29	624	384	21	5	603	3	600	1e-51	200
rs:WP_012896713	DNA topoisomerase III [Staphylococcus aureus].	30.98	552	348	16	5	544	3	533	1e-51	200
rs:WP_041114280	DNA topoisomerase [Bacillus badius].	27.73	631	398	17	4	603	1	604	1e-51	200
rs:WP_014726311	DNA topoisomerase [Burkholderia sp. KJ006].	30.12	581	354	17	7	547	5	573	1e-51	200
rs:WP_026581149	DNA topoisomerase III [Bacillus sp. J33].	28.44	538	355	15	7	530	4	525	1e-51	200
rs:WP_037549984	DNA topoisomerase III [Staphylococcus sp. TE8].	26.61	620	399	17	7	606	5	588	1e-51	200
rs:WP_010731122	DNA topoisomerase III [Enterococcus faecium].	29.52	586	365	19	5	563	3	567	1e-51	200
rs:WP_010200379	DNA topoisomerase III, partial [Pseudomonas amygdali].	34.12	422	250	10	145	548	4	415	1e-51	197
rs:WP_021388038	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.08	557	328	17	7	544	6	514	1e-51	199
rs:WP_002818003	DNA topoisomerase [Oenococcus oeni].	30.29	624	384	21	5	603	3	600	1e-51	200
rs:WP_041123572	DNA topoisomerase III [Jeotgalibacillus alimentarius].	29.48	553	347	18	5	544	4	526	1e-51	200
rs:WP_022072241	DNA topoisomerase III [Clostridium bartlettii CAG:1329].	29.25	547	339	15	7	544	6	513	1e-51	199
rs:WP_034225946	DNA topoisomerase, partial [Lachnobacterium bovis].	27.41	580	371	16	7	544	6	577	1e-51	199
rs:WP_009903124	DNA topoisomerase III [Peptoclostridium difficile].	29.23	561	322	17	7	544	6	514	1e-51	199
rs:WP_035976377	DNA topoisomerase III, partial [Bradyrhizobium sp. th.b2].	26.86	566	360	14	7	550	6	539	1e-51	199
rs:WP_031861664	DNA topoisomerase III [Staphylococcus aureus].	30.80	552	349	16	5	544	3	533	1e-51	199
rs:WP_002135700	DNA topoisomerase [Bacillus cereus].	28.25	616	395	18	7	601	5	594	1e-51	200
rs:WP_003374314	DNA topoisomerase [Clostridium botulinum].	28.46	629	393	21	7	602	5	609	1e-51	199
rs:WP_010680147	DNA topoisomerase III [Fusobacterium gonidiaformans].	29.65	543	327	18	7	539	4	501	1e-51	197
rs:WP_000366639	DNA topoisomerase [Streptococcus agalactiae].	28.78	542	333	16	7	539	4	501	1e-51	197
rs:WP_012584241	DNA topoisomerase III [Thauera sp. MZ1T].	29.86	566	358	20	7	550	6	554	1e-51	200
rs:WP_016215923	DNA topoisomerase III [Eubacterium sp. 14-2].	27.56	566	350	17	7	539	5	543	1e-51	200
rs:WP_011986253	DNA topoisomerase [Clostridium botulinum].	28.57	609	384	18	7	590	5	587	1e-51	198
rs:WP_039310023	DNA topoisomerase III [Clostridium botulinum].	28.32	579	364	17	3	559	2	551	1e-51	200
rs:WP_041716195	DNA topoisomerase III, partial [Alicycliphilus denitrificans].	32.46	382	233	10	8	380	5	370	1e-51	193
rs:WP_042512886	DNA topoisomerase [Bacillus cereus].	28.25	616	395	18	7	601	5	594	1e-51	199
rs:WP_025774955	DNA topoisomerase III [Clostridium botulinum].	28.57	609	384	18	7	590	5	587	1e-51	198
rs:WP_002322496	DNA topoisomerase III [Enterococcus faecium].	28.99	583	372	17	5	563	3	567	1e-51	199
rs:WP_023043254	DNA topoisomerase III [Enterococcus faecium].	28.99	583	372	17	5	563	3	567	1e-51	199
rs:WP_002821023	DNA topoisomerase [Oenococcus oeni].	30.29	624	384	21	5	603	3	600	1e-51	199
rs:WP_027642634	DNA topoisomerase III [[Clostridium] clostridioforme].	28.47	562	344	16	7	549	4	526	1e-51	199
rs:WP_005231974	DNA topoisomerase [Enterococcus casseliflavus].	29.36	562	354	17	5	544	3	543	1e-51	199
rs:WP_011949064	DNA topoisomerase [Clostridium botulinum].	28.57	609	384	18	7	590	5	587	1e-51	198
rs:WP_012099617	DNA topoisomerase III [Clostridium botulinum].	28.57	609	384	18	7	590	5	587	1e-51	198
rs:WP_038529514	DNA topoisomerase III [Formosa agariphila].	29.14	549	352	16	8	550	5	522	1e-51	200
rs:WP_035684265	DNA topoisomerase III [Flavobacterium reichenbachii].	29.84	553	343	18	8	550	5	522	1e-51	200
rs:WP_028529857	DNA topoisomerase III [Ruminococcus gauvreauii].	27.19	640	406	20	8	596	7	637	1e-51	199
rs:WP_044647002	DNA topoisomerase III [Paenibacillus terrae].	28.01	564	333	18	7	544	5	521	1e-51	199
rs:WP_000115176	DNA topoisomerase III [Bacillus cereus].	28.55	578	357	18	7	555	5	555	1e-51	199
rs:WP_033421242	DNA topoisomerase, partial [Lachnobacterium bovis].	27.59	580	370	16	7	544	6	577	1e-51	199
rs:WP_036146170	DNA topoisomerase III [Lysinibacillus fusiformis].	28.91	550	342	18	7	530	4	530	1e-51	199
rs:WP_034440668	DNA topoisomerase [Clostridiales bacterium S5-A11].	29.96	544	324	19	7	539	4	501	1e-51	197
rs:WP_029445302	DNA topoisomerase III [Cellulophaga baltica].	29.04	551	351	16	8	550	5	523	1e-51	200
rs:WP_006573250	DNA topoisomerase III [Pseudoflavonifractor capillosus].	28.39	560	345	15	7	549	4	524	1e-51	199
rs:WP_031462889	DNA topoisomerase III [Paenibacillus polymyxa].	27.92	566	332	21	7	544	5	522	1e-51	199
rs:WP_000114569	DNA topoisomerase III [Bacillus cereus].	28.79	587	343	21	7	554	5	555	1e-51	199
rs:WP_044927340	DNA topoisomerase, partial [Roseburia inulinivorans].	27.27	583	371	17	9	550	1	571	1e-51	198
rs:WP_009382803	DNA topoisomerase III [Staphylococcus massiliensis].	28.89	540	338	15	7	532	5	512	1e-51	199
rs:WP_031825561	DNA topoisomerase III, partial [Staphylococcus aureus].	30.80	552	349	16	5	544	3	533	1e-51	199
rs:WP_003696757	DNA topoisomerase III [Lactobacillus ruminis].	29.20	548	327	20	7	544	5	501	1e-51	199
rs:WP_024933790	DNA topoisomerase III [Clostridium botulinum].	28.57	609	384	18	7	590	5	587	1e-51	198
rs:WP_005237632	DNA topoisomerase [Enterococcus casseliflavus].	29.39	558	359	15	5	544	3	543	1e-51	199
rs:WP_021979153	DNA topoisomerase [Clostridium sp. CAG:793].	29.13	563	347	20	7	532	26	573	1e-51	199
rs:WP_044405324	DNA topoisomerase III [Rhodopseudomonas palustris].	27.84	546	342	13	7	530	6	521	1e-51	200
rs:WP_003478477	DNA topoisomerase [Clostridium perfringens].	27.80	615	385	21	7	590	5	591	1e-51	199
rs:WP_032448662	DNA topoisomerase III, partial [Klebsiella pneumoniae].	29.17	569	354	15	7	543	4	555	1e-51	197
rs:WP_042275571	DNA topoisomerase [Clostridium sp. 01].	29.24	595	384	16	7	590	4	572	1e-51	199
rs:WP_002326518	DNA topoisomerase III [Enterococcus faecium].	29.33	583	370	17	5	563	3	567	1e-51	199
rs:WP_040176477	DNA topoisomerase III, partial [Klebsiella pneumoniae].	29.17	569	354	15	7	543	4	555	2e-51	197
rs:WP_046159436	DNA topoisomerase [Streptococcus dysgalactiae].	28.41	542	335	16	7	539	4	501	2e-51	197
rs:WP_042145203	DNA topoisomerase [Paucisalibacillus sp. EB02].	29.47	604	376	22	7	585	4	582	2e-51	199
rs:WP_003358661	DNA topoisomerase III [Clostridium botulinum].	28.57	609	384	18	7	590	5	587	2e-51	198
rs:WP_044383536	DNA topoisomerase [Enterococcus faecium].	28.82	583	373	17	5	563	3	567	2e-51	199
rs:WP_035445052	DNA topoisomerase III, partial [Bacillus sp. UNC41MFS5].	28.68	544	346	17	7	530	4	525	2e-51	199
rs:WP_037542431	DNA topoisomerase III [Staphylococcus pseudintermedius].	28.19	564	365	15	7	559	6	540	2e-51	199
rs:WP_021375833	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.08	557	328	17	7	544	6	514	2e-51	199
rs:WP_027412801	DNA topoisomerase III [Aquimarina muelleri].	28.13	551	356	17	8	550	5	523	2e-51	199
rs:WP_039250550	DNA topoisomerase III [Clostridium novyi].	29.26	564	346	14	7	548	6	538	2e-51	199
rs:WP_006858739	DNA topoisomerase [Roseburia intestinalis].	28.08	577	355	19	7	539	6	566	2e-51	203
rs:WP_003524410	DNA topoisomerase III [[Clostridium] clostridioforme].	27.92	566	357	16	7	548	5	543	2e-51	199
rs:WP_019392302	DNA topoisomerase III [Bacillus endophyticus].	28.52	540	331	13	5	535	3	496	2e-51	199
rs:WP_002937562	DNA topoisomerase III [Thauera sp. 27].	30.22	556	346	20	7	540	6	541	2e-51	200
rs:WP_025613987	DNA topoisomerase III [Cellulophaga baltica].	29.04	551	351	16	8	550	5	523	2e-51	199
rs:WP_042742987	DNA topoisomerase III, partial [Staphylococcus aureus].	28.17	529	335	16	7	522	5	501	2e-51	196
rs:WP_008462312	DNA topoisomerase III [Flavobacterium sp. F52].	29.66	553	344	18	8	550	5	522	2e-51	199
rs:WP_045539673	DNA topoisomerase [Clostridium botulinum].	28.57	609	384	18	7	590	5	587	2e-51	198
rs:WP_041100934	DNA topoisomerase [Bacillus badius].	27.73	631	398	17	4	603	1	604	2e-51	199
rs:WP_002429351	DNA topoisomerase III, partial [Yersinia pestis].	26.84	529	360	12	7	519	4	521	2e-51	196
rs:WP_000063790	DNA topoisomerase [Bacillus cereus].	29.51	566	347	18	7	544	6	547	2e-51	199
rs:WP_003470899	DNA topoisomerase [Clostridium perfringens].	27.80	615	385	21	7	590	5	591	2e-51	199
rs:WP_010074359	DNA topoisomerase [Clostridium cellulovorans].	28.39	620	376	22	7	590	5	592	2e-51	199
rs:WP_002932995	DNA topoisomerase III [Thauera sp. 28].	30.40	556	345	20	7	540	6	541	2e-51	200
rs:WP_021652294	DNA topoisomerase [Blautia sp. KLE 1732].	29.25	547	342	16	7	532	5	527	2e-51	199
tr:F6IUN4_LACPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.25	588	366	19	3	563	2	566	2e-51	199
rs:WP_042743132	DNA topoisomerase III [Staphylococcus aureus].	30.80	552	349	16	5	544	3	533	2e-51	199
rs:WP_001094109	MULTISPECIES: DNA topoisomerase III [Bacilli].	30.80	552	349	16	5	544	3	533	2e-51	199
rs:WP_010714548	MULTISPECIES: DNA topoisomerase III, partial [Bacilli].	30.80	552	349	16	5	544	3	533	2e-51	199
rs:WP_034667368	DNA topoisomerase III [Cellulophaga sp. E6(2014)].	29.04	551	351	16	8	550	5	523	2e-51	199
rs:WP_012423151	DNA topoisomerase [Clostridium botulinum].	28.46	629	393	21	7	602	5	609	2e-51	199
rs:WP_031855974	DNA topoisomerase III [Vibrio parahaemolyticus].	30.32	564	334	18	4	532	1	540	2e-51	199
rs:WP_010726014	DNA topoisomerase III [Enterococcus faecium].	29.52	586	365	19	5	563	3	567	2e-51	199
rs:WP_042457656	DNA topoisomerase III [Bacillus sp. FF4].	27.59	551	371	13	7	544	4	539	2e-51	199
rs:WP_031792597	DNA topoisomerase III [Staphylococcus aureus].	30.80	552	349	16	5	544	3	533	2e-51	199
rs:WP_045352997	topoisomerase I [Lactobacillus plantarum].	29.54	589	359	19	5	563	3	565	2e-51	199
rs:WP_003491116	DNA topoisomerase III [Clostridium sporogenes].	28.85	610	381	19	7	590	5	587	2e-51	198
rs:WP_047209149	DNA topoisomerase III [Staphylococcus aureus].	30.80	552	349	16	5	544	3	533	2e-51	199
rs:WP_002347713	DNA topoisomerase III [Enterococcus faecium].	28.99	583	372	17	5	563	3	567	2e-51	198
rs:WP_031882778	DNA topoisomerase III, partial [Staphylococcus aureus].	30.80	552	349	16	5	544	3	533	2e-51	199
rs:WP_042124020	DNA topoisomerase III [Paenibacillus sp. FSL R5-0345].	28.83	562	335	17	5	544	3	521	2e-51	199
rs:WP_040202207	DNA topoisomerase III, partial [Klebsiella pneumoniae].	29.20	565	351	15	7	539	4	551	2e-51	196
rs:WP_003461793	DNA topoisomerase [Clostridium perfringens].	27.64	615	386	21	7	590	5	591	2e-51	199
rs:WP_016370345	DNA topoisomerase III [Lactobacillus paracasei].	28.89	623	395	20	4	603	2	599	2e-51	199
rs:WP_026714869	DNA topoisomerase III [Flavobacterium daejeonense].	29.09	550	351	16	8	550	5	522	2e-51	199
rs:WP_034630178	DNA topoisomerase III [Desulfotomaculum alcoholivorax].	29.44	574	356	21	7	559	5	550	2e-51	199
rs:WP_025364046	DNA topoisomerase III [Paenibacillus polymyxa].	27.74	566	333	21	7	544	5	522	2e-51	199
gpu:CP011588_29	DNA topoisomerase III [Enterobacter asburiae]	29.45	567	355	14	7	543	4	555	2e-51	199
rs:WP_022254546	DNA topoisomerase [Firmicutes bacterium CAG:466].	28.15	572	355	17	5	552	4	543	2e-51	199
rs:WP_029197378	DNA topoisomerase III [Paenibacillus alginolyticus].	28.10	573	336	18	7	555	5	525	2e-51	199
rs:WP_003481996	DNA topoisomerase [Clostridium perfringens].	27.97	615	384	21	7	590	5	591	2e-51	199
rs:WP_017646113	DNA topoisomerase III [Streptococcus agalactiae].	30.32	554	309	21	7	539	4	501	2e-51	197
rs:WP_035149399	DNA topoisomerase III [Clostridium tetanomorphum].	28.32	558	342	20	45	554	41	588	2e-51	199
rs:WP_031876719	DNA topoisomerase III [Staphylococcus aureus].	30.80	552	349	16	5	544	3	533	2e-51	199
rs:WP_021966620	DNA topoisomerase [Clostridium sp. CAG:149].	29.06	585	342	18	7	548	5	559	2e-51	199
rs:WP_004361566	DNA topoisomerase III [Thauera phenylacetica].	29.86	566	358	20	7	550	6	554	2e-51	199
rs:WP_022512351	DNA topoisomerase [Clostridium clostridioforme CAG:511].	27.74	566	358	16	7	548	5	543	2e-51	199
rs:WP_042882881	hypothetical protein [Cupriavidus necator].	29.02	603	363	20	10	565	10	594	2e-51	198
rs:WP_035674309	DNA topoisomerase III [Flavobacterium sp. 83].	29.57	558	343	18	8	550	5	527	2e-51	199
rs:WP_013721070	DNA topoisomerase III [Lactobacillus buchneri].	28.55	592	361	20	5	563	3	565	2e-51	199
tr:Q0SRJ7_CLOPS	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ABG87621.1};	27.64	615	386	21	7	590	5	591	2e-51	199
rs:WP_043031848	DNA topoisomerase [Clostridium botulinum].	28.85	610	381	19	7	590	5	587	2e-51	197
rs:WP_044906257	DNA topoisomerase III [[Clostridium] innocuum].	29.87	559	341	19	7	555	4	521	2e-51	198
tr:X6SVQ9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.66	553	314	18	7	539	4	501	3e-51	197
rs:WP_002338048	DNA topoisomerase III, partial [Enterococcus faecium].	29.09	550	353	14	38	572	15	542	3e-51	199
rs:WP_017426164	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	27.74	566	333	21	7	544	5	522	3e-51	199
rs:WP_012450313	DNA topoisomerase [Clostridium botulinum].	28.25	630	393	21	7	602	5	609	3e-51	199
rs:WP_035658874	DNA topoisomerase III [Flavobacterium sp. EM1321].	29.64	550	348	17	8	550	5	522	3e-51	199
rs:WP_002593270	DNA topoisomerase III [[Clostridium] clostridioforme].	27.74	566	358	16	7	548	5	543	3e-51	199
rs:WP_027642235	DNA topoisomerase III [[Clostridium] clostridioforme].	28.06	563	357	16	7	548	5	540	3e-51	199
rs:WP_010422921	DNA topoisomerase III [Anaerophaga thermohalophila].	29.19	555	347	18	8	550	5	525	3e-51	199
rs:WP_016290736	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	28.92	574	349	18	8	532	7	570	3e-51	198
rs:WP_041084686	DNA topoisomerase [Clostridium botulinum].	28.25	630	393	21	7	602	5	609	3e-51	199
rs:WP_035796762	DNA topoisomerase [Butyrivibrio sp. MB2005].	29.56	592	358	18	7	553	6	583	3e-51	201
rs:WP_046175909	hypothetical protein [Domibacillus indicus].	27.97	547	357	14	4	532	1	528	3e-51	198
rs:WP_011010711	DNA topoisomerase [Clostridium perfringens].	27.80	615	385	21	7	590	5	591	3e-51	199
rs:WP_031830982	hypothetical protein, partial [Vibrio parahaemolyticus].	33.70	365	228	8	35	389	2	362	3e-51	192
rs:WP_002479576	DNA topoisomerase III [Staphylococcus simulans].	27.00	563	373	14	7	559	5	539	3e-51	198
rs:WP_019117888	DNA topoisomerase III [Anaerococcus obesiensis].	28.97	542	332	17	7	539	4	501	3e-51	196
rs:WP_002586183	DNA topoisomerase III [[Clostridium] clostridioforme].	27.74	566	358	16	7	548	5	543	3e-51	198
rs:WP_003360737	DNA topoisomerase III [Clostridium botulinum].	28.57	609	384	18	7	590	5	587	3e-51	197
rs:WP_037598662	DNA topoisomerase [Streptococcus sp. AS20].	28.60	542	334	15	7	539	4	501	3e-51	196
rs:WP_002432733	DNA topoisomerase III [Staphylococcus capitis].	26.61	620	399	18	7	606	5	588	3e-51	198
gpu:CP006907_185	DNA topoisomerase family protein [Clostridium botulinum CDC_297]	28.57	609	384	18	7	590	5	587	3e-51	197
rs:WP_011379758	DNA topoisomerase III [Nitrosospira multiformis].	29.44	574	351	19	5	550	4	551	3e-51	199
rs:WP_028386704	DNA topoisomerase [Legionella geestiana].	27.89	545	360	12	8	530	5	538	3e-51	198
rs:WP_000779856	DNA topoisomerase III [Streptococcus pneumoniae].	29.48	553	315	19	7	539	4	501	3e-51	196
rs:WP_027126573	DNA topoisomerase III [Gelidibacter mesophilus].	28.78	549	354	16	8	550	5	522	3e-51	199
rs:WP_019166616	DNA topoisomerase III [Staphylococcus delphini].	28.09	566	363	16	7	559	6	540	3e-51	198
rs:WP_018591436	DNA topoisomerase [Terrisporobacter glycolicus].	29.41	595	383	17	7	590	4	572	3e-51	198
rs:WP_022153122	DNA topoisomerase [Firmicutes bacterium CAG:65].	27.38	577	358	18	7	532	6	572	3e-51	198
rs:WP_000115175	DNA topoisomerase III [Bacillus thuringiensis].	28.37	578	358	18	7	555	5	555	3e-51	198
rs:WP_002576947	DNA topoisomerase III [[Clostridium] bolteae].	27.94	562	347	16	7	549	4	526	3e-51	198
rs:WP_034230048	DNA topoisomerase, partial [Lachnobacterium bovis].	27.37	581	370	17	7	544	6	577	3e-51	199
rs:WP_044923300	DNA topoisomerase III [Lachnospiraceae bacterium MA2020].	26.83	656	411	24	5	607	4	643	3e-51	198
rs:WP_024479295	DNA topoisomerase III [Cellulophaga baltica].	29.04	551	351	16	8	550	5	523	3e-51	199
rs:WP_022280887	DNA topoisomerase [Lactobacillus ruminis CAG:367].	29.01	548	328	20	7	544	5	501	3e-51	198
rs:WP_005638697	DNA topoisomerase III [Parabacteroides merdae].	28.49	537	341	17	8	531	5	511	3e-51	198
rs:WP_027438062	DNA topoisomerase III [Lachnospira multipara].	27.51	607	373	19	5	554	4	600	4e-51	198
rs:WP_036756511	hypothetical protein [Photobacterium halotolerans].	26.72	580	380	15	15	559	12	581	4e-51	199
rs:WP_011591016	DNA topoisomerase [Clostridium perfringens].	27.64	615	386	21	7	590	5	591	4e-51	198
rs:WP_002843605	DNA topoisomerase III [Peptostreptococcus anaerobius].	29.15	542	331	17	7	539	4	501	4e-51	196
rs:WP_015262647	DNA topoisomerase III [Desulfitobacterium dichloroeliminans].	28.93	591	351	18	3	543	2	573	4e-51	199
rs:WP_003068295	DNA topoisomerase [Streptococcus intermedius].	28.78	542	333	16	7	539	4	501	4e-51	196
rs:WP_035651436	hypothetical protein, partial [Lachnospiraceae bacterium AD3010].	27.48	615	363	20	5	553	4	601	4e-51	197
rs:WP_036161385	DNA topoisomerase III [Lysinibacillus sphaericus].	28.67	558	332	19	7	530	4	529	4e-51	198
rs:WP_002824608	DNA topoisomerase [Oenococcus oeni].	30.13	624	385	21	5	603	3	600	4e-51	198
rs:WP_017825599	DNA topoisomerase [Clostridium botulinum].	28.25	630	393	21	7	602	5	609	4e-51	198
rs:WP_031419831	DNA topoisomerase III [Lysinibacillus sphaericus].	28.67	558	332	19	7	530	4	529	4e-51	198
rs:WP_003451558	DNA topoisomerase [Clostridium perfringens].	27.80	615	385	21	7	590	5	591	4e-51	198
rs:WP_012703748	DNA topoisomerase III [Clostridium botulinum].	28.41	609	385	18	7	590	5	587	4e-51	197
rs:WP_023014977	DNA topoisomerase III [Staphylococcus simulans].	26.95	564	372	16	7	559	5	539	4e-51	198
rs:WP_036156598	DNA topoisomerase III [Maribacter forsetii].	29.64	550	348	17	8	550	5	522	4e-51	198
rs:WP_000366636	DNA topoisomerase [Streptococcus agalactiae].	28.78	542	333	16	7	539	4	501	4e-51	196
rs:WP_031413506	DNA topoisomerase III [Brevibacillus laterosporus].	27.66	629	398	18	4	603	1	601	4e-51	198
rs:WP_022433308	DNA topoisomerase [Eubacterium sp. CAG:38].	28.16	593	370	21	5	554	4	583	4e-51	197
rs:WP_002303486	DNA topoisomerase III [Enterococcus faecium].	28.82	583	373	17	5	563	3	567	4e-51	197
rs:WP_016819759	DNA topoisomerase III [Paenibacillus polymyxa].	27.39	566	335	20	7	544	5	522	4e-51	198
rs:WP_015729516	DNA topoisomerase III [Staphylococcus pseudintermedius].	28.01	564	366	15	7	559	6	540	4e-51	198
rs:WP_028590838	DNA topoisomerase III [Paenibacillus panacisoli].	29.14	573	329	21	5	550	3	525	4e-51	198
rs:WP_024633551	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	29.42	588	338	21	5	563	3	542	4e-51	198
rs:WP_022321312	DNA topoisomerase III [Parabacteroides merdae CAG:48].	28.33	540	338	18	8	531	5	511	4e-51	198
rs:WP_041053511	DNA topoisomerase III [Jeotgalibacillus campisalis].	28.50	565	352	18	5	548	4	537	4e-51	198
rs:WP_036658025	DNA topoisomerase III [Paenibacillus larvae].	29.48	580	317	22	5	550	3	524	4e-51	198
rs:WP_022584315	DNA topoisomerase III [Brevibacillus laterosporus].	27.82	629	397	18	4	603	1	601	4e-51	198
rs:WP_003336735	DNA topoisomerase III [Brevibacillus laterosporus].	27.66	629	398	18	4	603	1	601	4e-51	198
rs:WP_041487960	DNA topoisomerase III, partial [Bacillus thuringiensis].	29.94	531	340	18	7	522	4	517	4e-51	195
rs:WP_003455196	DNA topoisomerase [Clostridium perfringens].	27.80	615	385	21	7	590	5	591	4e-51	198
rs:WP_047338674	hypothetical protein [Enterococcus cecorum].	28.60	570	350	17	4	546	2	541	4e-51	196
rs:WP_000779858	DNA topoisomerase III [Streptococcus agalactiae].	29.84	553	313	18	7	539	4	501	4e-51	196
rs:WP_032807128	topoisomerase I [Oenococcus oeni].	30.13	624	385	21	5	603	3	600	4e-51	198
rs:WP_046451949	DNA topoisomerase III [Bacteroides sp. UNK.MGS-14].	28.33	540	338	18	8	531	5	511	4e-51	198
rs:WP_012721099	DNA topoisomerase III [Clostridium botulinum].	28.57	609	384	18	7	590	5	587	4e-51	197
rs:WP_043921484	DNA topoisomerase III, partial [Paenibacillus polymyxa].	27.98	629	390	20	4	598	1	600	4e-51	197
tr:D6DE15_CLOSC	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.01	586	342	18	7	548	5	560	4e-51	198
rs:WP_003342705	DNA topoisomerase III [Brevibacillus laterosporus].	27.68	625	395	18	4	599	1	597	4e-51	198
rs:WP_012552822	DNA topoisomerase III [Lactobacillus casei].	28.62	622	396	20	5	603	3	599	4e-51	198
rs:WP_003486473	DNA topoisomerase III [Clostridium sporogenes].	28.85	610	381	19	7	590	5	587	4e-51	197
rs:WP_016612333	DNA topoisomerase [Enterococcus faecium].	29.21	558	360	15	5	544	3	543	4e-51	198
rs:WP_020999685	DNA topoisomerase III [Streptococcus anginosus].	28.14	622	368	22	7	606	6	570	4e-51	196
rs:WP_019741001	DNA topoisomerase III [Pseudomonas savastanoi].	27.21	588	384	14	7	565	4	576	4e-51	198
rs:WP_002332865	DNA topoisomerase III [Enterococcus faecium].	28.82	583	373	17	5	563	3	567	4e-51	197
rs:WP_026677034	DNA topoisomerase III [Fictibacillus gelatini].	30.62	516	309	17	39	530	38	528	4e-51	198
rs:WP_034043867	DNA topoisomerase III [Flaviramulus ichthyoenteri].	28.75	553	349	17	8	550	5	522	5e-51	198
rs:WP_035783947	DNA topoisomerase [Butyrivibrio sp. MC2021].	29.81	567	345	19	7	532	6	560	5e-51	201
rs:WP_043064063	DNA topoisomerase III [Aneurinibacillus migulanus].	28.23	620	394	17	4	599	1	593	5e-51	198
rs:WP_036166280	DNA topoisomerase III [Lysinibacillus sphaericus].	28.67	558	332	19	7	530	4	529	5e-51	198
rs:WP_003561259	DNA topoisomerase III [Lactobacillus buchneri].	28.89	592	359	19	5	563	3	565	5e-51	198
rs:WP_038880477	DNA topoisomerase III, partial [Vibrio jasicida].	28.04	567	370	13	8	549	5	558	5e-51	196
rs:WP_000114570	DNA topoisomerase III [Bacillus cereus].	29.07	578	353	19	7	554	5	555	5e-51	198
rs:WP_035408996	DNA topoisomerase III [Exiguobacterium sp. RIT341].	28.83	496	325	12	43	530	42	517	5e-51	198
rs:WP_026073519	DNA topoisomerase III [Bacillus massiliosenegalensis].	28.42	556	360	15	7	544	4	539	5e-51	198
rs:WP_038268239	DNA topoisomerase [[Clostridium] litorale].	27.47	608	393	17	7	590	5	588	5e-51	198
rs:WP_036227450	DNA topoisomerase III [Lysinibacillus sphaericus].	28.42	549	345	18	7	530	4	529	5e-51	198
rs:WP_022243205	DNA topoisomerase [Roseburia sp. CAG:45].	28.69	596	354	20	7	550	6	582	5e-51	200
rs:WP_022045540	DNA topoisomerase [Roseburia sp. CAG:18].	28.65	562	355	18	7	532	6	557	5e-51	201
rs:WP_004457833	DNA topoisomerase [Clostridium perfringens].	27.64	615	386	21	7	590	5	591	5e-51	198
tr:C7H2S2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.69	549	330	18	7	539	21	529	5e-51	197
rs:WP_033059191	MULTISPECIES: DNA topoisomerase III [Clostridium].	28.69	610	382	19	7	590	5	587	5e-51	197
rs:WP_034288008	DNA topoisomerase III [Helicobacter sp. MIT 11-5569].	26.93	583	377	17	7	559	4	567	5e-51	198
rs:WP_035393366	MULTISPECIES: DNA topoisomerase III [Clostridiales].	29.69	549	330	18	7	539	4	512	5e-51	197
rs:WP_020565900	hypothetical protein [Methylosarcina fibrata].	27.94	569	366	16	7	548	4	555	5e-51	198
rs:WP_026881876	DNA topoisomerase III [Clostridium akagii].	26.29	582	372	16	5	559	4	555	5e-51	198
rs:WP_043052039	DNA topoisomerase [Streptococcus equi].	29.84	553	313	17	7	539	4	501	5e-51	196
tr:C3DIJ7_BACTS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.94	531	340	18	7	522	4	517	5e-51	195
rs:WP_000366638	DNA topoisomerase [Streptococcus agalactiae].	28.60	542	334	16	7	539	4	501	5e-51	196
rs:WP_011677354	DNA topoisomerase [Oenococcus oeni].	30.45	624	383	21	5	603	3	600	5e-51	197
rs:WP_019167893	DNA topoisomerase III [Staphylococcus intermedius].	28.01	564	366	15	7	559	6	540	5e-51	197
rs:WP_022297090	DNA topoisomerase III [Clostridium sp. CAG:465].	29.55	572	344	19	7	532	5	563	5e-51	197
rs:WP_009537698	DNA topoisomerase [Oribacterium asaccharolyticum].	29.48	553	315	19	7	539	4	501	5e-51	196
rs:WP_019423519	DNA topoisomerase III [Paenibacillus sp. OSY-SE].	27.50	571	341	18	7	550	5	529	5e-51	197
rs:WP_009071258	DNA topoisomerase [Metallosphaera yellowstonensis].	30.07	542	315	20	7	539	4	490	6e-51	197
rs:WP_010775606	DNA topoisomerase III [Enterococcus faecalis].	29.15	542	331	16	7	539	4	501	6e-51	196
rs:WP_000779853	DNA topoisomerase III [Streptococcus agalactiae].	29.15	542	331	16	7	539	4	501	6e-51	196
rs:WP_002453790	DNA topoisomerase III [Staphylococcus capitis].	26.45	620	400	18	7	606	5	588	6e-51	197
rs:WP_008790738	MULTISPECIES: DNA topoisomerase III [Coprobacillus].	27.24	602	376	18	3	575	2	570	6e-51	197
rs:WP_018211376	DNA topoisomerase III [Desulfitobacterium hafniense].	28.98	559	360	16	5	539	4	549	6e-51	198
rs:WP_019117159	MULTISPECIES: DNA topoisomerase III [Clostridiales].	27.86	621	367	24	7	604	4	566	6e-51	196
tr:C9BZ11_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.82	583	373	17	5	563	33	597	6e-51	197
rs:WP_003031506	MULTISPECIES: DNA topoisomerase III [Streptococcus anginosus group].	30.09	545	322	20	7	539	4	501	6e-51	196
rs:WP_017498188	DNA topoisomerase III [Flavobacterium sp. WG21].	29.29	553	346	18	8	550	5	522	6e-51	198
rs:WP_044220056	DNA topoisomerase III [Flammeovirga pacifica].	29.17	545	331	17	8	531	5	515	6e-51	198
rs:WP_015474608	DNA topoisomerase III [Lactobacillus brevis].	28.00	625	396	20	5	603	3	599	6e-51	197
rs:WP_031599127	DNA topoisomerase III [Ferrovum myxofaciens].	29.00	538	340	18	8	531	5	514	6e-51	197
rs:WP_013620522	DNA topoisomerase III [Cellulophaga lytica].	28.38	532	343	16	8	531	5	506	6e-51	198
rs:WP_016304003	DNA topoisomerase III [Lachnospiraceae bacterium A2].	27.89	570	344	18	7	539	5	544	6e-51	197
rs:WP_034058450	DNA topoisomerase III [Lacinutrix sp. PAMC 27137].	29.09	550	351	17	8	550	5	522	6e-51	198
rs:WP_002576397	DNA topoisomerase III [[Clostridium] bolteae].	29.87	549	329	18	7	539	4	512	6e-51	197
tr:D6DF30_CLOSC	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.45	561	351	15	7	549	4	526	6e-51	197
rs:WP_002301798	DNA topoisomerase III [Enterococcus faecium].	28.47	583	375	17	5	563	3	567	6e-51	197
rs:WP_038507278	DNA topoisomerase III [Cellulophaga lytica].	28.38	532	343	16	8	531	5	506	6e-51	198
rs:WP_009221177	DNA topoisomerase III [Lachnospiraceae oral taxon 107].	29.64	550	322	20	7	539	4	505	6e-51	196
tr:A0A098EYV3_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.60	598	384	17	7	582	5	581	7e-51	197
rs:WP_001235774	hypothetical protein, partial [Escherichia coli].	28.85	565	361	14	7	543	4	555	7e-51	197
tr:A0A0D0I5N4_BACTM	SubName: Full=TopB protein {ECO:0000313|EMBL:KIP26822.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIP26822.1};	29.94	531	340	18	7	522	4	517	7e-51	194
rs:WP_002346936	DNA topoisomerase III [Enterococcus faecium].	28.82	583	373	17	5	563	3	567	7e-51	197
rs:WP_035785837	DNA topoisomerase [Clostridium botulinum].	28.30	629	394	21	7	602	5	609	7e-51	197
rs:WP_027066133	DNA topoisomerase III [Maribacter sp. Hel_I_7].	29.09	550	351	17	8	550	5	522	7e-51	197
rs:WP_010724052	DNA topoisomerase III [Enterococcus faecium].	28.84	579	376	15	5	563	3	565	7e-51	197
rs:WP_045091551	DNA topoisomerase III [Clostridium sp. FS41].	29.15	566	339	18	7	557	4	522	7e-51	197
rs:WP_004336217	DNA topoisomerase III [Thauera linaloolentis].	29.52	559	348	17	7	540	6	543	7e-51	198
tr:E8LH21_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.22	556	314	18	7	539	6	510	7e-51	197
rs:WP_042598621	DNA topoisomerase III, partial [Bacillus thuringiensis].	29.94	531	340	18	7	522	4	517	7e-51	194
rs:WP_015474661	DNA topoisomerase III [Lactobacillus brevis].	28.89	585	368	19	5	563	3	565	7e-51	197
rs:WP_002578949	MULTISPECIES: DNA topoisomerase III [Firmicutes].	30.22	556	314	18	7	539	4	508	7e-51	197
rs:WP_008901381	DNA topoisomerase [Peptoniphilus duerdenii].	27.86	621	367	24	7	604	4	566	7e-51	195
rs:WP_010691817	DNA topoisomerase III [Treponema denticola].	29.91	565	338	20	5	549	3	529	7e-51	197
rs:WP_019107256	DNA topoisomerase III [Peptoniphilus senegalensis].	27.86	621	367	24	7	604	4	566	7e-51	195
rs:WP_016098187	DNA topoisomerase III [Bacillus cereus].	28.08	616	396	18	7	601	5	594	7e-51	197
tr:G5GKY2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.27	550	324	18	7	539	21	522	7e-51	196
rs:WP_034645991	DNA topoisomerase III [Cellulophaga geojensis].	28.38	532	343	16	8	531	5	506	7e-51	197
rs:WP_040215770	DNA topoisomerase III, partial [Klebsiella pneumoniae].	29.17	569	354	15	7	543	4	555	7e-51	197
rs:WP_021960535	DNA topoisomerase III [Butyrivibrio crossotus CAG:259].	27.90	595	366	18	8	553	6	586	7e-51	197
rs:WP_002567851	DNA topoisomerase III [[Clostridium] bolteae].	28.75	567	348	18	7	548	5	540	7e-51	197
tr:D4LMY3_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.91	550	340	16	7	532	5	527	7e-51	197
rs:WP_041060515	DNA topoisomerase III [Jeotgalibacillus campisalis].	29.53	569	341	18	5	544	3	540	7e-51	197
rs:WP_008634317	DNA topoisomerase III [Bizionia argentinensis].	29.53	552	346	17	8	550	5	522	8e-51	197
rs:WP_034552094	DNA topoisomerase III [Carnobacterium funditum].	29.89	562	354	17	4	548	3	541	8e-51	197
rs:WP_026833507	DNA topoisomerase III [Exiguobacterium undae].	29.92	498	317	15	43	530	42	517	8e-51	197
rs:WP_041845987	DNA topoisomerase III [Bacillus thermoamylovorans].	28.90	557	356	16	7	544	4	539	8e-51	197
rs:WP_027414696	DNA topoisomerase III [Aneurinibacillus terranovensis].	28.78	556	337	14	7	544	5	519	8e-51	197
rs:WP_005603390	DNA topoisomerase III [Butyrivibrio crossotus].	27.73	595	367	17	8	553	6	586	8e-51	197
rs:WP_013994551	DNA topoisomerase III [Zobellia galactanivorans].	29.45	550	349	17	8	550	5	522	8e-51	197
rs:WP_027136773	DNA topoisomerase III [Gaetbulibacter saemankumensis].	29.29	553	346	18	8	550	5	522	8e-51	197
rs:WP_046724002	DNA topoisomerase III [Paenibacillus durus].	27.26	565	339	15	7	544	5	524	9e-51	197
rs:WP_030034759	DNA topoisomerase III [Clostridium botulinum].	28.69	610	382	19	7	590	5	587	9e-51	196
rs:WP_025271989	DNA topoisomerase [Streptococcus anginosus].	28.60	542	334	16	7	539	4	501	9e-51	195
rs:WP_040883102	DNA topoisomerase [Johnsonella ignava].	29.27	550	324	18	7	539	1	502	9e-51	195
rs:WP_040109448	DNA topoisomerase III [Jeotgalibacillus sp. D5].	29.29	553	334	15	7	539	8	523	9e-51	197
rs:WP_010652035	DNA topoisomerase [Oceanobacillus massiliensis].	28.16	625	396	20	4	599	2	602	9e-51	197
rs:WP_010217635	DNA topoisomerase III [Pseudomonas amygdali].	26.90	591	388	14	4	565	1	576	9e-51	197
rs:WP_006745733	DNA topoisomerase III [Bacteroides coprosuis].	28.20	610	389	19	7	602	2	576	9e-51	196
rs:WP_019364747	hypothetical protein [Pseudomonas luteola].	28.72	564	355	14	1	539	1	542	9e-51	197
rs:WP_021250390	DNA topoisomerase III [Thauera terpenica].	29.15	566	362	18	7	550	6	554	9e-51	198
rs:WP_025719810	DNA topoisomerase III [Paenibacillus polymyxa].	26.84	570	333	15	7	544	5	522	9e-51	197
rs:WP_006749824	DNA topoisomerase III [Burkholderia ambifaria].	29.17	528	333	15	48	547	43	557	1e-50	197
tr:R2RSK6_ENTCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.21	558	360	15	5	544	9	549	1e-50	197
rs:WP_040649807	DNA topoisomerase III [Ruminococcaceae bacterium D16].	30.47	558	310	18	7	539	4	508	1e-50	197
rs:WP_036764317	DNA topoisomerase [Peptostreptococcus sp. MV1].	27.42	620	371	22	7	604	4	566	1e-50	195
rs:WP_027130995	DNA topoisomerase [Gemella cuniculi].	28.60	542	334	17	7	539	6	503	1e-50	195
tr:A0A096HU54_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.72	585	369	18	5	563	3	565	1e-50	197
rs:WP_027634967	DNA topoisomerase [Clostridium butyricum].	28.60	598	379	18	7	579	5	579	1e-50	197
rs:WP_040435932	DNA topoisomerase III [[Clostridium] hylemonae].	27.39	566	361	16	7	548	5	544	1e-50	197
rs:WP_031859997	DNA topoisomerase III [Staphylococcus aureus].	30.62	552	350	16	5	544	3	533	1e-50	197
rs:WP_024040672	DNA topoisomerase [Clostridium butyricum].	28.67	600	376	19	7	579	5	579	1e-50	197
rs:WP_007649183	DNA topoisomerase III [Formosa sp. AK20].	28.49	558	350	18	8	550	5	528	1e-50	197
rs:WP_034695777	DNA topoisomerase [Enterococcus casseliflavus].	29.21	558	360	15	5	544	3	543	1e-50	197
rs:WP_006816384	DNA topoisomerase III [Providencia rustigianii].	29.00	562	363	14	7	543	4	554	1e-50	197
rs:WP_043664505	DNA topoisomerase [Clostridium butyricum].	28.60	598	379	18	7	579	5	579	1e-50	197
rs:WP_013725751	DNA topoisomerase III [Clostridium botulinum].	28.80	566	348	22	8	532	7	558	1e-50	197
rs:WP_040800395	DNA topoisomerase III [Stomatobaculum longum].	28.45	608	359	24	7	555	5	595	1e-50	196
rs:WP_000259050	DNA topoisomerase III [Streptococcus agalactiae].	29.07	633	352	22	4	602	2	571	1e-50	195
rs:WP_003321296	DNA topoisomerase [Bacillus alcalophilus].	28.37	557	357	17	7	543	4	538	1e-50	197
rs:WP_002589689	MULTISPECIES: DNA topoisomerase III [Clostridiales].	28.75	567	348	18	7	548	5	540	1e-50	197
rs:WP_022426443	DNA topoisomerase [Ruminococcus sp. CAG:90].	28.73	550	341	16	7	532	5	527	1e-50	197
rs:WP_042968702	DNA topoisomerase III [Escherichia coli].	27.10	572	380	15	8	557	5	561	1e-50	197
rs:WP_025481450	DNA topoisomerase III [Enterococcus faecium].	28.99	583	372	17	5	563	3	567	1e-50	196
rs:WP_042775764	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	30.14	564	335	19	4	532	1	540	1e-50	194
rs:WP_016569421	DNA topoisomerase III [Pseudomonas syringae].	26.90	591	388	14	4	565	1	576	1e-50	197
rs:WP_028106718	DNA topoisomerase III [Exiguobacterium undae].	29.92	498	317	15	43	530	42	517	1e-50	196
rs:WP_000259049	DNA topoisomerase III [Streptococcus agalactiae].	29.07	633	352	22	4	602	2	571	1e-50	195
tr:C0C5H6_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.39	566	361	16	7	548	17	556	1e-50	197
rs:WP_009257933	DNA topoisomerase III [Lachnospiraceae bacterium 7_1_58FAA].	29.86	556	316	19	7	539	4	508	1e-50	196
rs:WP_036293217	hypothetical protein [Methylobacter whittenburyi].	28.70	554	362	14	8	549	5	537	1e-50	196
rs:WP_028557675	DNA topoisomerase III [Paenibacillus sp. URHA0014].	28.78	556	330	17	7	539	5	517	1e-50	196
rs:WP_039240526	DNA topoisomerase III [Clostridium botulinum].	28.80	566	348	22	8	532	7	558	1e-50	197
rs:WP_035129939	DNA topoisomerase [Clostridium sulfidigenes].	27.68	625	386	21	7	590	5	604	1e-50	197
rs:WP_002577786	DNA topoisomerase III [[Clostridium] bolteae].	28.75	567	348	18	7	548	5	540	1e-50	197
rs:WP_036142091	DNA topoisomerase III [Lysinibacillus sp. BF-4].	27.67	553	370	13	5	544	3	538	1e-50	196
rs:WP_026475568	DNA topoisomerase III [Alkaliflexus imshenetskii].	28.99	552	351	17	8	550	5	524	1e-50	197
rs:WP_014202755	DNA topoisomerase III [Owenweeksia hongkongensis].	28.86	544	332	17	8	531	5	513	1e-50	197
rs:WP_021003063	DNA topoisomerase III [Streptococcus intermedius].	29.80	547	321	21	7	539	4	501	1e-50	194
rs:WP_023510288	DNA topoisomerase III [Sporolactobacillus laevolacticus].	27.88	556	320	18	3	534	2	500	1e-50	196
rs:WP_044231725	DNA topoisomerase III [Porphyromonas sp. COT-290 OH3588].	27.69	567	355	16	7	546	2	540	1e-50	196
rs:WP_046525659	DNA topoisomerase III [Bacillus sp. SA2-6].	28.04	624	359	22	7	603	5	565	1e-50	196
rs:WP_004407605	DNA topoisomerase III, partial [Pseudomonas syringae].	32.13	389	239	11	8	387	5	377	1e-50	190
rs:WP_041079115	DNA topoisomerase III [Staphylococcus saprophyticus].	27.24	624	391	20	7	606	5	589	1e-50	196
rs:WP_009662899	DNA topoisomerase III [Lachnoanaerobaculum sp. ICM7].	27.83	618	377	22	7	605	4	571	1e-50	194
rs:WP_038693551	DNA topoisomerase III [Paenibacillus stellifer].	27.85	571	338	17	7	550	5	528	1e-50	196
rs:WP_005644013	DNA topoisomerase III [Parabacteroides merdae].	28.49	537	341	17	8	531	5	511	1e-50	196
rs:WP_033795056	DNA topoisomerase [Enterococcus faecium].	28.76	591	372	17	5	563	3	576	1e-50	197
rs:WP_021397960	DNA topoisomerase III family protein [Peptoclostridium difficile].	30.22	556	314	18	7	539	4	508	1e-50	196
rs:WP_022473457	DNA topoisomerase [Sutterella sp. CAG:521].	28.65	548	363	14	1	534	1	534	1e-50	197
tr:R8NBQ2_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.80	566	353	18	5	544	3	544	1e-50	194
rs:WP_031834541	DNA topoisomerase III, partial [Staphylococcus aureus].	28.01	532	339	16	43	559	7	509	1e-50	196
rs:WP_002576342	MULTISPECIES: DNA topoisomerase III [Lachnospiraceae].	27.73	559	352	15	7	549	4	526	1e-50	196
rs:WP_032823667	topoisomerase I [Oenococcus oeni].	30.13	624	385	21	5	603	3	600	1e-50	196
rs:WP_032121812	DNA topoisomerase [Clostridium sp. LF2].	28.34	607	388	19	7	590	5	587	1e-50	195
rs:WP_040209776	DNA topoisomerase III [Klebsiella pneumoniae].	29.17	569	354	15	7	543	4	555	1e-50	197
rs:WP_015846389	DNA topoisomerase III [Paenibacillus sp. JDR-2].	27.63	637	366	18	7	604	5	585	1e-50	196
rs:WP_022451462	DNA topoisomerase [Clostridium sp. CAG:269].	27.02	581	359	15	7	532	4	574	1e-50	196
rs:WP_010709815	DNA topoisomerase III [Enterococcus faecalis].	29.02	572	350	18	5	544	3	550	1e-50	196
rs:WP_042210448	DNA topoisomerase III [Paenibacillus borealis].	29.23	561	331	18	7	544	5	522	2e-50	196
rs:WP_029497743	DNA topoisomerase III [Kurthia huakuii].	28.55	557	338	19	7	539	6	526	2e-50	196
rs:WP_002579403	DNA topoisomerase III [Clostridium butyricum].	28.67	600	376	19	7	579	5	579	2e-50	196
rs:WP_044960767	DNA topoisomerase III [Faecalibacterium prausnitzii].	27.69	567	354	15	1	549	1	529	2e-50	196
rs:WP_036185771	hypothetical protein, partial [Lysinibacillus manganicus].	29.54	518	324	14	47	547	36	529	2e-50	196
rs:WP_031868422	DNA topoisomerase III, partial [Staphylococcus aureus].	28.01	532	339	16	43	559	6	508	2e-50	196
rs:WP_011860791	DNA topoisomerase [Peptoclostridium difficile].	28.62	552	321	18	7	539	4	501	2e-50	194
rs:WP_035762558	DNA topoisomerase [Clostridium butyricum].	28.67	600	376	19	7	579	5	579	2e-50	196
rs:WP_004199098	MULTISPECIES: DNA topoisomerase III [Bacteria].	29.17	569	354	15	7	543	4	555	2e-50	197
rs:WP_047198600	DNA topoisomerase [Streptococcus agalactiae].	29.29	553	316	18	7	539	4	501	2e-50	194
tr:F4XGQ5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.47	558	310	18	7	539	45	549	2e-50	196
rs:WP_022614817	DNA topoisomerase [Vibrio nigripulchritudo].	29.26	557	346	17	4	532	1	537	2e-50	196
rs:WP_025479193	DNA topoisomerase, partial [Enterococcus faecium].	29.80	547	346	17	5	531	3	531	2e-50	194
tr:A0A0A2VYV2_BEABA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.08	478	305	12	110	564	14	480	2e-50	194
rs:WP_038568657	DNA topoisomerase III [Paenibacillus odorifer].	28.70	561	337	17	5	544	3	521	2e-50	196
rs:WP_025115653	DNA topoisomerase III [Lysinibacillus fusiformis].	28.78	549	343	19	7	530	4	529	2e-50	196
rs:WP_042184736	DNA topoisomerase III [Paenibacillus sp. FSL H7-0737].	28.65	562	336	17	5	544	3	521	2e-50	196
rs:WP_012443232	DNA topoisomerase III [Erwinia tasmaniensis].	27.69	632	407	18	7	599	4	624	2e-50	196
rs:WP_036573498	DNA topoisomerase [Oceanobacillus picturae].	28.34	607	389	19	7	590	4	587	2e-50	196
rs:WP_022792534	DNA topoisomerase III [Marinococcus halotolerans].	27.50	571	354	16	4	544	1	541	2e-50	196
tr:A8SHN5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.69	567	354	15	1	549	3	531	2e-50	196
rs:WP_031420250	DNA topoisomerase III [Vibrio parahaemolyticus].	29.96	564	336	18	4	532	1	540	2e-50	196
rs:WP_011875776	DNA topoisomerase [Burkholderia vietnamiensis].	30.82	558	330	19	7	531	6	540	2e-50	197
rs:WP_046057802	DNA topoisomerase [Clostridium sp. IBUN62F].	28.67	600	376	19	7	579	5	579	2e-50	196
rs:WP_007896555	DNA topoisomerase III [Streptococcus pseudoporcinus].	29.29	553	316	18	7	539	4	501	2e-50	194
rs:WP_026801823	DNA topoisomerase III [Pontibacillus halophilus].	30.00	570	346	19	5	548	4	546	2e-50	196
rs:WP_008721172	DNA topoisomerase III [Clostridiales bacterium 1_7_47FAA].	28.12	569	348	18	7	548	5	539	2e-50	196
rs:WP_002588924	MULTISPECIES: DNA topoisomerase III [Clostridiales].	27.76	562	348	15	7	549	4	526	2e-50	196
tr:A0A081BJM0_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.28	633	392	20	1	603	1	601	2e-50	196
rs:WP_004802669	DNA topoisomerase III [Eggerthia catenaformis].	27.30	608	371	18	7	590	4	564	2e-50	196
rs:WP_006678765	DNA topoisomerase III [Paenibacillus dendritiformis].	27.82	568	339	16	7	550	5	525	2e-50	196
rs:WP_022091491	DNA topoisomerase [Lachnospiraceae bacterium CAG:25].	29.58	551	331	18	7	544	5	511	2e-50	196
rs:WP_021963596	DNA topoisomerase III [Prevotella sp. CAG:1185].	29.10	543	337	15	7	531	2	514	2e-50	196
rs:WP_044031624	DNA topoisomerase [Enterococcus faecium].	29.16	583	371	17	5	563	3	567	2e-50	196
rs:WP_019913667	DNA topoisomerase III [Paenibacillus sp. HW567].	27.94	562	337	17	7	544	5	522	2e-50	196
rs:WP_009221186	DNA topoisomerase III [Lachnospiraceae oral taxon 107].	29.27	550	324	19	7	539	4	505	2e-50	194
rs:WP_011763832	DNA topoisomerase III [Azoarcus sp. BH72].	29.49	590	364	21	7	566	6	573	2e-50	197
rs:WP_010096889	DNA topoisomerase [Ornithinibacillus scapharcae].	28.09	623	392	21	7	598	4	601	2e-50	196
rs:WP_025022469	DNA topoisomerase III [Lactobacillus hayakitensis].	29.32	556	327	20	7	550	5	506	2e-50	196
rs:WP_041142936	topoisomerase I [Lactobacillus plantarum].	28.38	592	362	20	5	563	3	565	2e-50	196
rs:WP_040208500	MULTISPECIES: DNA topoisomerase III [Bacillus].	29.52	542	344	17	7	530	4	525	2e-50	196
rs:WP_034545084	DNA topoisomerase [Clostridiales bacterium S7-1-4].	27.42	620	371	22	7	604	4	566	2e-50	194
tr:H8LFB1_ENTFU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.16	583	371	17	5	563	4	568	2e-50	196
tr:A0A096H590_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.27	626	393	21	5	603	3	599	2e-50	196
rs:WP_022477608	DNA topoisomerase [Coraliomargarita sp. CAG:312].	30.77	559	334	22	7	539	5	536	2e-50	196
rs:WP_043366110	DNA topoisomerase III, partial [Belnapia sp. F-4-1].	26.81	567	359	15	7	550	6	539	2e-50	195
rs:WP_046298229	DNA topoisomerase III [Verrucomicrobia bacterium IMCC26134].	30.80	578	327	23	7	539	5	554	2e-50	197
rs:WP_035425603	DNA topoisomerase III [Bacillus sp. L1(2012)].	29.20	572	369	18	43	599	42	592	2e-50	196
rs:WP_003428725	DNA topoisomerase [Clostridium butyricum].	28.67	600	376	19	7	579	5	579	2e-50	196
rs:WP_001562921	DNA topoisomerase III [Escherichia coli].	27.10	572	380	15	8	557	5	561	2e-50	196
rs:WP_042876255	DNA topoisomerase III, partial [Bacillus cereus].	31.35	453	269	13	116	548	3	433	2e-50	195
rs:WP_000209235	DNA topoisomerase III [Bacillus cereus].	29.36	579	354	20	5	554	3	555	2e-50	196
rs:WP_041501265	topoisomerase I [Lactobacillus heilongjiangensis].	28.89	585	368	19	5	563	3	565	2e-50	196
tr:A0A0C7RDW4_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEQ13906.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEQ13906.1};	28.81	597	382	18	7	590	4	570	2e-50	196
rs:WP_036822275	DNA topoisomerase III [Pontibacillus yanchengensis].	27.94	562	356	17	7	544	6	542	2e-50	196
rs:WP_008101325	DNA topoisomerase [Verrucomicrobiae bacterium DG1235].	29.76	551	332	18	4	531	1	519	2e-50	196
tr:A0A0C7IT59_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEO21894.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEO21894.1};	28.81	597	382	18	7	590	4	570	2e-50	196
rs:WP_022075325	DNA topoisomerase [Firmicutes bacterium CAG:212].	28.32	558	349	16	7	539	6	537	2e-50	196
rs:WP_029333124	DNA topoisomerase III [Exiguobacterium oxidotolerans].	29.05	537	345	16	7	530	4	517	3e-50	196
rs:WP_017473361	hypothetical protein [Amphibacillus jilinensis].	28.03	553	350	16	7	534	4	533	3e-50	196
rs:WP_021985184	DNA topoisomerase [Clostridium sp. CAG:127].	27.50	600	373	18	8	554	6	596	3e-50	195
rs:WP_044875527	DNA topoisomerase III [Paenibacillus sp. IHBB 10380].	27.83	575	329	17	7	550	5	524	3e-50	196
tr:Q3MN26_LACPA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.31	580	372	17	5	563	3	565	3e-50	196
rs:WP_008175979	DNA topoisomerase III [Bacillus sp. B14905].	28.23	549	346	18	7	530	4	529	3e-50	196
rs:WP_036845770	DNA topoisomerase III [Porphyromonas cangingivalis].	29.63	621	372	26	7	602	2	582	3e-50	195
rs:WP_016085280	DNA topoisomerase III [Bacillus cereus].	27.74	584	365	16	7	556	5	565	3e-50	196
rs:WP_017187990	DNA topoisomerase III [Vibrio harveyi].	29.91	565	335	19	4	532	1	540	3e-50	196
rs:WP_045450152	DNA topoisomerase III [Burkholderia sp. RPE67].	28.55	578	380	16	7	568	6	566	3e-50	197
tr:A0A0D4ZYL4_STAEP	SubName: Full=Putative relaxase TraI {ECO:0000313|EMBL:AJW29115.1};	30.22	556	347	15	5	544	3	533	3e-50	196
rs:WP_025483685	DNA topoisomerase III [Clostridiales bacterium VE202-28].	28.12	569	348	18	7	548	5	539	3e-50	196
rs:WP_022375467	DNA topoisomerase [Firmicutes bacterium CAG:270].	28.96	549	337	16	7	544	5	511	3e-50	196
rs:WP_044632471	DNA topoisomerase III [Tamlana sedimentorum].	28.70	554	349	17	8	550	5	523	3e-50	196
rs:WP_003375986	DNA topoisomerase III [Clostridium botulinum].	29.15	566	346	23	8	532	7	558	3e-50	196
rs:WP_037567095	DNA topoisomerase III [Staphylococcus agnetis].	28.14	565	364	17	7	559	5	539	3e-50	196
rs:WP_031587950	DNA topoisomerase III [Lachnospiraceae bacterium P6A3].	29.91	585	336	21	8	532	7	577	3e-50	195
rs:WP_012344603	DNA topoisomerase III [Clostridium botulinum].	28.41	609	385	18	7	590	5	587	3e-50	194
rs:WP_046835674	DNA topoisomerase III [Staphylococcus succinus].	27.63	637	372	24	7	606	5	589	3e-50	196
rs:WP_024838128	DNA topoisomerase III [Clostridium sp. 12(A)].	27.85	571	348	15	7	548	5	540	3e-50	196
rs:WP_039234196	DNA topoisomerase III [Clostridium sp. K25].	29.15	566	346	23	8	532	7	558	3e-50	196
rs:WP_042232421	DNA topoisomerase III [Paenibacillus sp. FSL R5-0912].	28.52	561	335	16	7	544	5	522	3e-50	196
rs:WP_018371562	DNA topoisomerase [Streptococcus massiliensis].	28.60	542	334	16	7	539	4	501	3e-50	194
rs:WP_044638498	DNA topoisomerase III [Siansivirga zeaxanthinifaciens].	28.73	550	353	18	8	550	5	522	3e-50	196
rs:WP_024737330	DNA topoisomerase III [Clostridiales bacterium VE202-15].	27.69	567	358	17	7	548	5	544	3e-50	196
rs:WP_019468637	MULTISPECIES: DNA topoisomerase III [Staphylococcus].	28.43	619	390	21	7	606	5	589	3e-50	196
rs:WP_002842318	DNA topoisomerase [Finegoldia magna].	28.62	566	328	20	7	551	4	514	3e-50	194
tr:C3CTB0_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.99	545	347	12	11	539	3	523	3e-50	196
rs:WP_025788905	DNA topoisomerase III [Vibrio parahaemolyticus].	29.86	566	356	16	8	547	5	555	3e-50	196
rs:WP_028562548	DNA topoisomerase III [Paenibacillus pinihumi].	27.75	627	373	20	7	604	5	580	3e-50	195
rs:WP_039310314	DNA topoisomerase III [Paenibacillus sp. IHB B 3415].	28.60	556	331	16	7	539	5	517	3e-50	195
rs:WP_027702382	DNA topoisomerase [[Clostridium] mangenotii].	29.83	600	373	18	7	590	4	571	3e-50	196
rs:WP_033559033	DNA topoisomerase III [Escherichia coli].	28.85	565	359	14	7	543	4	553	3e-50	196
rs:WP_006122530	DNA topoisomerase III [Pantoea stewartii].	26.32	589	381	15	7	563	5	572	3e-50	196
tr:A0A078MCC0_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.65	562	368	15	7	556	6	546	3e-50	195
rs:WP_000259052	hypothetical protein [Streptococcus agalactiae].	28.22	567	339	17	4	550	2	520	3e-50	194
rs:WP_016106882	DNA topoisomerase III [Bacillus cereus].	28.60	577	361	19	5	554	3	555	3e-50	195
rs:WP_040744842	DNA topoisomerase III, partial [alpha proteobacterium BAL199].	26.89	569	360	15	7	552	6	541	3e-50	194
rs:WP_017684961	DNA topoisomerase III [Pseudomonas syringae].	26.57	591	390	14	4	565	1	576	3e-50	194
rs:WP_040994040	DNA topoisomerase III [Chryseobacterium oranimense].	30.33	544	326	20	8	531	5	515	3e-50	195
rs:WP_003407083	DNA topoisomerase III [Pseudomonas syringae].	27.03	592	387	15	4	565	1	577	4e-50	195
rs:WP_044342681	DNA topoisomerase III [Pseudomonas oryzihabitans].	27.17	552	355	18	34	546	33	576	4e-50	196
rs:WP_042533544	DNA topoisomerase [Oceanobacillus oncorhynchi].	27.79	619	387	19	3	590	2	591	4e-50	195
rs:WP_043291748	hypothetical protein, partial [Burkholderia vietnamiensis].	26.88	573	372	16	8	548	6	563	4e-50	194
rs:WP_040757782	DNA topoisomerase III, partial [Vibrio scophthalmi].	27.45	561	381	12	7	549	4	556	4e-50	195
rs:WP_032716084	DNA topoisomerase III [Enterobacter aerogenes].	28.85	565	359	14	7	543	4	553	4e-50	196
rs:WP_021349356	DNA topoisomerase III [Lactobacillus fermentum].	28.62	622	396	20	5	603	3	599	4e-50	195
rs:WP_026494579	DNA topoisomerase [Butyrivibrio sp. WCD3002].	29.22	592	360	18	7	553	6	583	4e-50	198
rs:WP_013656949	DNA topoisomerase III [Cellulosilyticum lentocellum].	29.44	574	352	21	7	559	6	547	4e-50	195
rs:WP_012263515	TrsI [Staphylococcus aureus].	30.29	548	357	14	5	544	3	533	4e-50	195
rs:WP_023610339	DNA topoisomerase III [Streptococcus pyogenes].	28.97	542	332	16	7	539	4	501	4e-50	193
rs:WP_039217288	MULTISPECIES: DNA topoisomerase III [Clostridium].	29.15	566	346	23	8	532	7	558	4e-50	195
rs:WP_002838913	DNA topoisomerase III [Finegoldia magna].	28.62	566	328	20	7	551	4	514	4e-50	193
rs:WP_044705422	DNA topoisomerase III [Escherichia coli].	27.10	572	380	15	8	557	5	561	4e-50	195
rs:WP_031410708	DNA topoisomerase III [Vibrio parahaemolyticus].	29.96	564	336	18	4	532	1	540	4e-50	195
rs:WP_041348767	DNA topoisomerase [Clostridium botulinum].	28.41	609	385	18	7	590	5	587	4e-50	194
rs:WP_010014514	DNA topoisomerase III [Lactobacillus coryniformis].	27.84	625	397	19	5	603	3	599	4e-50	195
rs:WP_041030302	DNA topoisomerase III, partial [Salmonella enterica].	30.62	418	271	10	147	552	5	415	4e-50	192
rs:WP_012621109	DNA topoisomerase III [Lactobacillus gasseri].	27.97	622	394	20	8	603	7	600	4e-50	195
tr:V5M5L7_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.94	553	339	14	7	532	2	516	4e-50	195
rs:WP_003030107	DNA topoisomerase [Streptococcus anginosus].	28.25	616	381	18	4	603	2	572	4e-50	193
rs:WP_016526810	DNA topoisomerase [Lactobacillus plantarum].	29.38	582	369	18	5	563	3	565	4e-50	195
rs:WP_014642662	DNA topoisomerase III [Halobacillus halophilus].	28.82	569	350	18	7	548	6	546	4e-50	195
rs:WP_004838439	DNA topoisomerase [Anaerococcus vaginalis].	27.42	620	371	22	7	604	4	566	4e-50	193
rs:WP_011345748	DNA topoisomerase TraE [Xanthomonas euvesicatoria].	24.92	594	395	13	1	549	1	588	4e-50	195
rs:WP_005782553	MULTISPECIES: DNA topoisomerase III [Pseudomonas syringae group].	27.58	591	384	15	4	565	1	576	4e-50	195
tr:C0FRI7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	27.49	582	369	17	10	550	2	571	4e-50	196
rs:WP_003590797	DNA topoisomerase III [Lactobacillus casei].	28.00	625	396	20	5	603	3	599	5e-50	195
rs:WP_019155274	DNA topoisomerase III [Bacillus massiliosenegalensis].	26.78	549	349	14	7	546	5	509	5e-50	195
rs:WP_016083876	DNA topoisomerase III [Bacillus cereus].	27.65	586	365	16	7	556	5	567	5e-50	195
rs:WP_000779850	DNA topoisomerase III [Streptococcus agalactiae].	29.29	553	316	18	7	539	4	501	5e-50	193
rs:WP_003414269	DNA topoisomerase [Clostridium butyricum].	28.67	600	376	19	7	579	5	579	5e-50	195
rs:WP_025708278	DNA topoisomerase III [Paenibacillus graminis].	28.88	561	333	17	7	544	5	522	5e-50	195
rs:WP_036693314	DNA topoisomerase III [Paenibacillus sp. FSL R7-269].	28.52	561	335	16	7	544	5	522	5e-50	195
rs:WP_032585756	DNA topoisomerase III [Campylobacter jejuni].	27.69	585	368	18	8	559	5	567	5e-50	195
rs:WP_003497037	DNA topoisomerase 3 [[Clostridium] symbiosum].	28.75	546	340	17	5	535	4	515	5e-50	194
rs:WP_034121403	hypothetical protein, partial [Peptococcaceae bacterium BICA1-7].	30.99	568	335	19	5	550	6	538	5e-50	193
rs:WP_019716635	DNA topoisomerase III, partial [Pseudomonas syringae].	26.50	634	408	18	4	598	1	615	5e-50	194
rs:WP_027415690	DNA topoisomerase [Aneurinibacillus terranovensis].	27.26	598	392	16	4	579	1	577	5e-50	195
tr:A0A0A7U658_LACBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.84	593	358	21	5	563	3	565	5e-50	195
rs:WP_010170286	DNA topoisomerase III [Bacillus coahuilensis].	27.50	571	366	18	5	559	3	541	5e-50	195
rs:WP_024399802	DNA topoisomerase [Streptococcus suis].	27.43	627	370	21	5	606	3	569	5e-50	193
rs:WP_009003768	DNA topoisomerase III [Clostridium sp. D5].	27.22	562	357	15	7	544	5	538	5e-50	195
rs:WP_000090078	DNA topoisomerase III [Bacillus thuringiensis].	28.91	543	346	12	13	539	2	520	5e-50	195
rs:WP_002144421	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	29.12	577	354	19	7	554	5	555	5e-50	195
rs:WP_028408833	DNA topoisomerase [Bacillus sp. 171095_106].	28.27	619	398	19	7	601	4	600	5e-50	195
rs:WP_046921879	DNA topoisomerase III [Lactobacillus ruminis].	28.91	543	325	20	7	539	5	496	5e-50	194
rs:WP_036835670	DNA topoisomerase III [Pontibacillus litoralis].	28.83	607	386	21	7	601	5	577	5e-50	194
rs:WP_007084794	DNA topoisomerase III [Bacillus bataviensis].	27.54	541	356	14	7	530	4	525	5e-50	195
tr:F9RIF7_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.45	561	381	12	7	549	5	557	5e-50	195
rs:WP_028870997	DNA topoisomerase III [Psychroserpens burtonensis].	29.29	536	335	16	8	531	5	508	5e-50	195
tr:A0A0C7Q4Q1_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEP92298.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEP92298.1};	28.81	597	382	18	7	590	4	570	5e-50	195
rs:WP_007895166	DNA topoisomerase III [Streptococcus pseudoporcinus].	29.11	553	317	19	7	539	6	503	6e-50	193
tr:V1S057_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.62	418	271	10	147	552	14	424	6e-50	192
rs:WP_025391090	DNA topoisomerase III [Pseudomonas syringae].	27.13	634	404	19	4	598	1	615	6e-50	195
rs:WP_040239307	DNA topoisomerase [Xanthomonas citri].	30.49	574	342	21	7	550	6	552	6e-50	195
tr:A0A0C7JSX9_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEO32215.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEO32215.1};	28.64	597	383	18	7	590	4	570	6e-50	195
rs:WP_016343946	DNA topoisomerase [Burkholderia sp. RPE64].	28.50	579	379	17	7	568	6	566	6e-50	196
rs:WP_032593162	DNA topoisomerase III [Campylobacter jejuni].	27.69	585	368	18	8	559	5	567	6e-50	195
rs:WP_044624791	DNA topoisomerase III [Tamlana nanhaiensis].	28.70	554	349	18	8	550	5	523	6e-50	195
rs:WP_019875135	DNA topoisomerase [Lactobacillus paracasei].	29.20	589	361	20	5	563	3	565	6e-50	194
rs:WP_009346275	DNA topoisomerase III [Peptoniphilus sp. oral taxon 836].	29.11	553	317	18	7	539	4	501	6e-50	192
rs:WP_035792465	DNA topoisomerase [Butyrivibrio sp. AE3006].	29.39	592	359	18	7	553	6	583	6e-50	197
rs:WP_024028720	DNA topoisomerase III [Bacillus vireti].	28.33	540	353	15	7	530	4	525	6e-50	194
rs:WP_021128957	DNA topoisomerase [[Clostridium] sordellii].	28.64	597	383	18	7	590	4	570	6e-50	194
rs:WP_028545721	DNA topoisomerase III [Paenibacillus taiwanensis].	27.22	562	340	15	7	544	5	521	6e-50	194
rs:WP_040434002	DNA topoisomerase III [Erysipelatoclostridium ramosum].	27.67	571	372	16	3	559	2	545	6e-50	194
rs:WP_033399204	hypothetical protein, partial [Desulfospira joergensenii].	30.20	553	346	17	4	543	1	526	6e-50	195
rs:WP_026815025	DNA topoisomerase III [Arenibacter certesii].	27.62	554	363	15	4	550	1	523	6e-50	195
rs:WP_002107335	DNA topoisomerase III [Bacillus cereus].	29.09	581	349	21	7	554	6	556	6e-50	194
rs:WP_020303949	hypothetical protein [Pseudomonas syringae].	27.41	591	385	15	4	565	1	576	6e-50	194
tr:B0N116_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.67	571	372	16	3	559	13	556	6e-50	194
rs:WP_004666997	DNA topoisomerase III [Pseudomonas savastanoi].	26.40	591	391	14	4	565	1	576	7e-50	194
sp:TOP3_STAS1	RecName: Full=DNA topoisomerase 3 {ECO:0000255|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000255|HAMAP-Rule:MF_00953};	27.02	618	400	18	7	606	5	589	7e-50	194
rs:WP_039098910	topoisomerase I [Lactobacillus curvatus].	28.55	592	361	19	5	563	3	565	7e-50	194
tr:X7RGR9_VIBPH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.91	565	337	19	3	532	14	554	7e-50	194
rs:WP_022004444	DNA topoisomerase III [Firmicutes bacterium CAG:194].	27.38	599	369	17	6	550	5	591	7e-50	194
rs:WP_046235799	DNA topoisomerase III [Pseudomonas syringae pv. coryli].	26.50	634	408	18	4	598	1	615	7e-50	194
rs:WP_015594677	DNA topoisomerase III [Bacillus sp. 1NLA3E].	27.89	545	349	15	7	530	4	525	8e-50	194
tr:S2SI22_LACPA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.89	585	368	19	5	563	3	565	8e-50	194
rs:WP_044039552	DNA topoisomerase III [Clostridium sp. M2/40].	29.10	591	357	21	8	554	7	579	8e-50	194
rs:WP_045721118	DNA topoisomerase III, partial [Salmonella enterica].	29.95	434	285	10	131	552	17	443	8e-50	192
rs:WP_028561132	DNA topoisomerase III [Paenibacillus pinihumi].	28.77	563	344	17	5	539	3	536	8e-50	194
rs:WP_040120508	DNA topoisomerase III [Klebsiella pneumoniae].	29.00	569	355	15	7	543	4	555	8e-50	194
rs:WP_022372341	DNA topoisomerase [Sutterella sp. CAG:397].	29.89	562	360	18	5	550	3	546	8e-50	195
tr:M5JHB5_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.44	423	249	14	7	418	5	397	8e-50	189
rs:WP_025678387	DNA topoisomerase III, partial [Paenibacillus massiliensis].	28.67	572	333	20	5	550	3	525	8e-50	193
tr:A0A0A8VTK4_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.64	597	383	18	7	590	4	570	8e-50	194
rs:WP_000209240	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	28.84	579	357	20	5	554	3	555	8e-50	194
rs:WP_012294074	DNA topoisomerase III [Lysinibacillus sphaericus].	28.60	556	335	20	7	530	4	529	8e-50	194
rs:WP_034528476	topoisomerase I [Lactobacillus oryzae].	28.30	629	389	20	5	603	3	599	8e-50	194
rs:WP_008344184	DNA topoisomerase [Burkholderia sp. SJ98].	30.31	574	343	21	7	550	6	552	8e-50	195
rs:WP_024651600	DNA topoisomerase III [Pseudomonas syringae].	27.41	591	385	15	4	565	1	576	9e-50	194
rs:WP_016511107	DNA topoisomerase III [Lactobacillus plantarum].	27.53	632	390	20	5	603	3	599	9e-50	194
rs:WP_039832234	DNA topoisomerase III [Paenibacillus sonchi].	28.34	561	336	16	7	544	5	522	9e-50	194
rs:WP_031922917	DNA topoisomerase III, partial [Staphylococcus aureus].	30.22	556	347	16	5	544	3	533	9e-50	192
rs:WP_009264856	DNA topoisomerase III [Lachnospiraceae bacterium 5_1_63FAA].	29.58	551	331	18	7	544	5	511	9e-50	194
rs:WP_045372352	DNA topoisomerase III [Jejuia pallidilutea].	28.36	550	355	16	8	550	5	522	9e-50	194
rs:WP_014386915	DNA topoisomerase [Pediococcus claussenii].	28.67	593	359	21	5	563	3	565	9e-50	194
rs:WP_035333217	hypothetical protein [Bacillus firmus].	28.25	630	399	20	3	607	2	603	9e-50	194
rs:WP_012678206	DNA topoisomerase [Streptococcus equi].	28.23	542	336	16	7	539	4	501	9e-50	192
tr:A0A0C7RPC2_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEQ09394.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEQ09394.1};	28.64	597	383	18	7	590	4	570	9e-50	194
rs:WP_019686166	DNA topoisomerase III [Paenibacillus polymyxa].	27.92	566	332	20	7	544	5	522	9e-50	194
rs:WP_046923262	DNA topoisomerase III [Lactobacillus ruminis].	28.83	548	329	20	7	544	5	501	9e-50	194
rs:WP_044684362	DNA topoisomerase [Streptococcus suis].	29.66	553	314	19	7	539	4	501	9e-50	192
rs:WP_043741665	DNA topoisomerase III [Thauera sp. SWB20].	30.04	556	347	20	7	540	6	541	9e-50	195
rs:WP_021977241	DNA topoisomerase [Ruminococcus sp. CAG:17].	27.85	553	341	16	7	532	5	526	9e-50	194
rs:WP_019640460	DNA topoisomerase III [Paenibacillus fonticola].	27.21	588	345	18	5	559	3	540	9e-50	194
rs:WP_018412454	DNA topoisomerase III [Methyloversatilis sp. NVD].	29.73	555	340	20	7	531	6	540	1e-49	195
rs:WP_040249095	DNA topoisomerase III [Psychroserpens mesophilus].	28.49	558	349	18	8	550	5	527	1e-49	194
rs:WP_006439101	DNA topoisomerase III [[Clostridium] hiranonis].	29.98	547	327	18	7	539	6	510	1e-49	194
rs:WP_018662174	DNA topoisomerase III [Bacillus acidiproducens].	27.55	548	355	12	3	530	2	527	1e-49	194
rs:WP_040982951	DNA topoisomerase [Oceanobacillus sp. S5].	28.48	611	390	18	7	592	4	592	1e-49	194
rs:WP_047334783	DNA topoisomerase III [Enterococcus cecorum].	28.24	556	335	20	7	550	5	508	1e-49	194
rs:WP_007860969	MULTISPECIES: DNA topoisomerase III [Clostridiales].	27.70	574	350	17	7	548	5	545	1e-49	194
rs:WP_042506224	DNA topoisomerase III [Algibacter lectus].	28.91	550	352	16	8	550	5	522	1e-49	194
rs:WP_046513834	DNA topoisomerase III [Cryomorphaceae bacterium ASP10-05a].	28.21	553	353	17	8	550	5	523	1e-49	194
rs:WP_002597119	DNA topoisomerase III [Clostridium colicanis].	27.20	614	380	18	7	579	5	592	1e-49	194
tr:R8CJY7_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.62	580	357	18	7	556	5	557	1e-49	194
tr:A0A069DGA2_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.24	569	335	17	7	544	5	525	1e-49	194
rs:WP_036159633	hypothetical protein, partial [Lysinibacillus odysseyi].	28.71	620	379	18	7	598	5	589	1e-49	194
rs:WP_005956640	DNA topoisomerase III [Peptoniphilus harei].	27.54	621	369	24	7	604	4	566	1e-49	192
rs:WP_016224225	DNA topoisomerase III [Lachnospiraceae bacterium 3-2].	26.24	583	358	13	7	544	5	560	1e-49	194
rs:WP_036851418	DNA topoisomerase III [Porphyromonas cangingivalis].	29.47	621	373	26	7	602	2	582	1e-49	193
tr:D4RK56_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.50	583	369	18	5	563	4	568	1e-49	194
rs:WP_028229620	DNA topoisomerase [Burkholderia ferrariae].	30.31	574	343	21	7	550	6	552	1e-49	194
rs:WP_025333127	DNA topoisomerase III [Paenibacillus sabinae].	27.22	562	341	15	7	544	5	522	1e-49	194
rs:WP_026883648	DNA topoisomerase III [Clostridium akagii].	27.92	616	400	18	7	603	4	594	1e-49	194
rs:WP_036949281	DNA topoisomerase, partial [Pseudobutyrivibrio ruminis].	28.31	597	369	18	7	554	6	592	1e-49	194
rs:WP_029865550	DNA topoisomerase III [Vibrio parahaemolyticus].	30.32	564	334	19	4	532	1	540	1e-49	194
rs:WP_002482608	DNA topoisomerase III [Staphylococcus saprophyticus].	27.02	618	400	18	7	606	5	589	1e-49	194
rs:WP_036952801	DNA topoisomerase, partial [Pseudobutyrivibrio ruminis].	27.42	598	373	18	7	554	6	592	1e-49	194
tr:A0A0C7HPT5_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEN96764.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEN96764.1};	28.64	597	383	18	7	590	4	570	1e-49	194
rs:WP_002989354	MULTISPECIES: DNA topoisomerase III [Streptococcus].	29.10	543	330	18	7	539	4	501	1e-49	192
rs:WP_042770153	DNA topoisomerase III [Vibrio parahaemolyticus].	29.96	564	336	19	4	532	1	540	1e-49	194
rs:WP_042074080	DNA topoisomerase III, partial [Escherichia coli].	30.62	418	271	10	147	552	5	415	1e-49	191
rs:WP_025041234	DNA topoisomerase III [Nitrosospira briensis].	29.35	569	358	17	5	550	4	551	1e-49	194
rs:WP_008688344	DNA topoisomerase III [Eubacterium sp. 3_1_31].	27.46	568	355	16	5	550	3	535	1e-49	194
tr:A0A0D0PZV8_9BACI	SubName: Full=Contig8, whole genome shotgun sequence {ECO:0000313|EMBL:KIQ91353.1};	26.62	556	343	14	4	532	1	518	1e-49	194
rs:WP_034978567	DNA topoisomerase I [Epilithonimonas lactis].	27.46	590	354	17	4	552	1	557	1e-49	194
rs:WP_033704841	DNA topoisomerase [Enterococcus faecium].	29.50	583	369	18	5	563	3	567	1e-49	194
rs:WP_014779928	DNA topoisomerase III [Thiocystis violascens].	29.41	561	344	15	5	539	3	537	1e-49	194
rs:WP_018395281	DNA topoisomerase [Bacillus sp. 37MA].	27.30	619	404	19	7	601	6	602	1e-49	194
rs:WP_001996279	DNA topoisomerase III [Bacillus cereus].	29.07	578	353	19	7	554	6	556	1e-49	194
rs:WP_034145118	DNA topoisomerase III [Desulfosporosinus sp. BICA1-9].	28.57	581	360	18	5	550	4	564	1e-49	194
rs:WP_006717210	DNA topoisomerase III [Desulfitobacterium metallireducens].	27.02	607	372	18	7	557	6	597	1e-49	194
rs:WP_023625750	DNA topoisomerase III [Bacillus sp. 17376].	28.16	618	365	22	7	603	5	564	1e-49	193
rs:WP_045227513	DNA topoisomerase III, partial [Escherichia coli].	31.14	395	253	10	170	552	4	391	1e-49	190
tr:A0A0C7T5M5_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEQ28293.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEQ28293.1};	28.64	597	383	18	7	590	4	570	1e-49	194
rs:WP_039107789	topoisomerase I [Lactobacillus brevis].	28.81	590	362	19	5	563	3	565	1e-49	194
rs:WP_020425541	DNA topoisomerase III [Paenibacillus riograndensis].	27.76	562	338	16	7	544	5	522	1e-49	194
rs:WP_018885393	DNA topoisomerase III [Paenibacillus massiliensis].	28.85	572	332	20	5	550	3	525	1e-49	194
rs:WP_038535745	DNA topoisomerase [Bacillus sp. X1(2014)].	26.92	613	398	17	4	590	2	590	1e-49	194
rs:WP_006566731	MULTISPECIES: DNA topoisomerase III [Anaerostipes].	27.88	556	343	14	7	548	6	517	1e-49	193
tr:A0A090WWP2_9FLAO	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.91	550	352	16	8	550	5	522	1e-49	194
rs:WP_027098238	DNA topoisomerase [Clostridium paraputrificum].	28.09	598	382	17	7	579	5	579	1e-49	194
tr:A4JFS2_BURVG	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.88	573	372	16	8	548	6	563	1e-49	194
rs:WP_001094104	DNA topoisomerase III [Bacillus cereus].	28.86	596	335	23	5	554	3	555	1e-49	194
rs:WP_019035128	DNA topoisomerase III [Peptoniphilus lacrimalis].	29.32	556	338	16	7	553	4	513	1e-49	192
rs:WP_040976237	DNA topoisomerase [Pasteurella sp. FF6].	27.86	542	338	16	7	539	4	501	1e-49	192
rs:WP_007790064	DNA topoisomerase [Peptostreptococcus stomatis].	29.26	557	311	20	7	539	4	501	1e-49	192
rs:WP_035509775	DNA topoisomerase III [Burkholderia sp. MP-1].	28.20	578	382	16	7	568	6	566	1e-49	194
rs:WP_025789167	DNA topoisomerase III [Vibrio parahaemolyticus].	30.14	564	335	19	4	532	1	540	1e-49	194
tr:A0A0C7G0C3_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEN75959.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEN75959.1};	28.64	597	383	18	7	590	4	570	1e-49	193
rs:WP_044923880	DNA topoisomerase III [Anaerostipes hadrus].	29.58	551	331	18	7	544	5	511	1e-49	193
tr:A0A0C7TBY2_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEQ30985.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEQ30985.1};	28.64	597	383	18	7	590	4	570	1e-49	193
rs:WP_042095835	DNA topoisomerase III, partial [Escherichia coli].	30.62	418	271	10	147	552	7	417	1e-49	191
rs:WP_009203344	DNA topoisomerase [Anaerostipes hadrus].	29.58	551	331	18	7	544	5	511	1e-49	193
rs:WP_018977667	hypothetical protein [Saccharibacillus kuerlensis].	26.76	639	398	19	7	603	4	614	1e-49	194
rs:WP_008391092	DNA topoisomerase III [Clostridium sp. SS2/1].	29.58	551	331	18	7	544	5	511	2e-49	193
rs:WP_031599028	DNA topoisomerase III, partial [Pseudomonas savastanoi].	27.26	587	383	15	8	565	5	576	2e-49	192
tr:U2EZI4_CLOS4	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.27	561	352	16	7	549	6	528	2e-49	193
rs:WP_042498112	hypothetical protein, partial [Algibacter lectus].	28.73	550	353	16	8	550	5	522	2e-49	194
rs:WP_002556105	DNA topoisomerase III [Pseudomonas savastanoi].	27.07	591	387	15	4	565	1	576	2e-49	193
rs:WP_002326882	DNA topoisomerase III [Enterococcus faecium].	30.00	560	354	17	5	544	3	544	2e-49	193
rs:WP_019142232	DNA topoisomerase III [Herbaspirillum massiliense].	28.84	593	378	19	3	571	2	574	2e-49	194
tr:A0A0C7JCB9_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEO26515.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEO26515.1};	28.64	597	383	18	7	590	4	570	2e-49	193
tr:A0A0D3RLA6_LACRE	SubName: Full=TrsI, DNA Topoisomerase {ECO:0000313|EMBL:AJS10517.1};	28.84	586	367	19	5	563	3	565	2e-49	193
rs:WP_028282183	DNA topoisomerase III [Olleya marilimosa].	28.36	550	355	17	8	550	5	522	2e-49	194
tr:M5RIR6_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.84	534	334	16	35	548	10	517	2e-49	193
rs:WP_015017147	DNA topoisomerase III [Streptococcus dysgalactiae].	29.10	543	330	18	7	539	4	501	2e-49	191
rs:WP_047172050	DNA topoisomerase III [Staphylococcus xylosus].	26.68	566	372	18	7	559	5	540	2e-49	193
rs:WP_043934594	DNA topoisomerase III [Bacillus sp. EB01].	29.13	563	330	20	7	548	5	519	2e-49	193
tr:A0A075G5E7_9EURY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.73	577	385	15	7	567	5	565	2e-49	194
rs:WP_026777671	DNA topoisomerase III [Polaribacter sp. Hel_I_88].	28.36	536	339	16	8	531	5	507	2e-49	194
rs:WP_035004309	DNA topoisomerase III, partial [Betaproteobacteria bacterium MOLA814].	29.03	565	346	18	5	531	3	550	2e-49	194
rs:WP_043711949	topoisomerase I [Weissella cibaria].	28.81	597	362	19	5	563	3	574	2e-49	193
rs:WP_030061483	MULTISPECIES: DNA topoisomerase III [Staphylococcus].	30.04	556	348	15	5	544	3	533	2e-49	193
rs:WP_012375808	DNA topoisomerase III [Opitutus terrae].	29.58	578	330	19	7	539	5	550	2e-49	195
tr:G0LYH7_LACPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.21	582	370	18	5	563	3	565	2e-49	193
rs:WP_024727223	DNA topoisomerase III [Clostridiales bacterium VE202-09].	27.62	554	347	13	7	548	6	517	2e-49	193
rs:WP_031500110	DNA topoisomerase III [Vibrio parahaemolyticus].	30.14	564	335	19	4	532	1	540	2e-49	193
rs:WP_024668846	DNA topoisomerase III, partial [Pseudomonas syringae].	27.24	591	386	15	4	565	1	576	2e-49	193
rs:WP_005746149	DNA topoisomerase III [Pseudomonas amygdali].	27.07	591	387	15	4	565	1	576	2e-49	193
rs:WP_025481001	DNA topoisomerase [Enterococcus faecium].	30.02	583	366	18	5	563	3	567	2e-49	193
rs:WP_021385283	DNA topoisomerase [Peptoclostridium difficile].	29.03	596	384	17	7	590	4	572	2e-49	193
tr:A0A0A1S3R0_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.48	597	384	18	7	590	4	570	2e-49	193
rs:WP_044992660	DNA topoisomerase III [Clostridium sp. ATCC 29733].	27.27	561	352	16	7	549	4	526	2e-49	193
rs:WP_023059217	DNA topoisomerase III [Peptoniphilus sp. BV3AC2].	28.45	566	329	20	7	551	4	514	2e-49	191
rs:WP_014343770	DNA topoisomerase III [Aliivibrio fischeri].	30.02	493	305	15	8	482	5	475	2e-49	190
rs:WP_006861796	DNA topoisomerase III [Marvinbryantia formatexigens].	28.69	589	366	19	8	554	7	583	2e-49	193
tr:A0A0C7S4V2_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEQ22916.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEQ22916.1};	28.64	597	383	18	7	590	4	570	2e-49	193
tr:V5AJ64_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.03	565	346	18	5	531	3	550	2e-49	194
tr:D4N0D7_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	29.58	551	331	18	7	544	5	511	2e-49	193
rs:WP_036764085	DNA topoisomerase [Peptostreptococcus sp. MV1].	28.74	609	393	17	7	599	4	587	2e-49	193
rs:WP_016099670	DNA topoisomerase III [Bacillus cereus].	26.62	556	343	14	4	532	1	518	2e-49	193
rs:WP_009899115	DNA topoisomerase [Peptoclostridium difficile].	29.37	555	354	16	8	548	6	536	2e-49	193
rs:WP_042825262	hypothetical protein [Xanthomonas axonopodis].	24.92	594	395	13	1	549	1	588	2e-49	193
rs:WP_021426560	DNA topoisomerase [Peptoclostridium difficile].	29.19	596	383	17	7	590	4	572	2e-49	193
rs:WP_009893975	MULTISPECIES: DNA topoisomerase [Firmicutes].	29.41	544	311	17	7	531	4	493	2e-49	191
rs:WP_024980194	DNA topoisomerase III [Flavobacterium succinicans].	29.21	558	345	18	8	550	5	527	2e-49	193
rs:WP_014190097	DNA topoisomerase III [Burkholderia sp. YI23].	28.37	578	381	16	7	568	6	566	2e-49	194
rs:WP_022619468	DNA topoisomerase [Peptoclostridium difficile].	29.37	555	354	16	8	548	6	536	2e-49	193
rs:WP_036962358	DNA topoisomerase III [Providencia alcalifaciens].	28.65	562	365	13	7	543	4	554	2e-49	193
rs:WP_036649449	DNA topoisomerase III [Paenibacillus pini].	29.06	554	320	17	7	532	5	513	2e-49	193
tr:A8TU58_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.02	570	358	16	7	552	6	541	2e-49	193
tr:A0A0C7I5E1_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEO07878.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEO07878.1};	28.64	597	383	18	7	590	4	570	2e-49	193
rs:WP_032508493	DNA topoisomerase III, partial [Peptoclostridium difficile].	29.03	596	384	17	7	590	4	572	2e-49	191
rs:WP_021393351	DNA topoisomerase III [Peptoclostridium difficile].	28.41	542	335	17	7	539	4	501	2e-49	191
rs:WP_042722664	DNA topoisomerase I, partial [Flavobacterium sp. B17].	29.73	528	317	16	7	509	4	502	2e-49	190
rs:WP_006439044	DNA topoisomerase III [[Clostridium] hiranonis].	29.05	599	381	17	7	590	4	573	2e-49	193
rs:WP_046041317	topoisomerase I [Lactobacillus plantarum].	27.75	627	395	20	5	603	3	599	2e-49	193
rs:WP_000209237	DNA topoisomerase III [Bacillus cereus].	28.72	585	350	21	5	554	3	555	2e-49	193
rs:WP_031555562	DNA topoisomerase III [Lachnospira multipara].	27.51	607	373	20	5	554	4	600	2e-49	192
tr:A0A0C7NNS0_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEP79536.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEP79536.1};	28.48	597	384	18	7	590	4	570	2e-49	193
rs:WP_021851957	DNA topoisomerase III [Prevotella sp. CAG:1058].	28.70	547	334	18	7	531	2	514	2e-49	192
rs:WP_024700499	DNA topoisomerase III [Vibrio parahaemolyticus].	30.14	564	335	19	4	532	1	540	2e-49	193
rs:WP_022221047	DNA topoisomerase [Coprococcus comes CAG:19].	27.97	572	353	18	7	548	5	547	2e-49	193
rs:WP_016647531	DNA topoisomerase III [Campylobacter ureolyticus].	26.92	587	375	16	7	563	4	566	2e-49	193
rs:WP_003416718	DNA topoisomerase [Peptoclostridium difficile].	29.19	596	383	17	7	590	4	572	2e-49	193
rs:WP_028892471	DNA topoisomerase III [Tenacibaculum sp. 47A_GOM-205m].	27.99	536	341	16	8	531	5	507	2e-49	193
rs:WP_026893097	DNA topoisomerase III [[Clostridium] aerotolerans].	27.67	571	349	15	7	548	5	540	2e-49	193
rs:WP_025838455	DNA topoisomerase III [Porphyromonas cangingivalis].	29.47	621	373	26	7	602	2	582	2e-49	192
rs:WP_033154848	DNA topoisomerase, partial [Pseudobutyrivibrio ruminis].	28.55	599	366	19	7	554	6	593	2e-49	193
rs:WP_034638122	DNA topoisomerase [Bacillus manliponensis].	27.88	617	396	19	7	601	5	594	2e-49	193
rs:WP_004257270	DNA topoisomerase III [Thauera sp. 63].	29.14	556	352	17	7	540	6	541	2e-49	194
rs:WP_021320572	DNA topoisomerase [Streptococcus equi].	28.75	553	319	18	7	539	4	501	2e-49	191
rs:WP_047199997	DNA topoisomerase [Streptococcus agalactiae].	29.48	553	315	18	7	539	4	501	2e-49	191
tr:A0A0C7LPY8_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEP45178.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEP45178.1};	28.64	597	383	18	7	590	4	570	2e-49	193
rs:WP_016128093	DNA topoisomerase III [Bacillus cereus].	28.64	583	353	21	5	554	3	555	2e-49	193
rs:WP_009224508	DNA topoisomerase III [Paenibacillus sp. oral taxon 786].	28.08	584	340	21	5	559	3	535	2e-49	193
rs:WP_018365297	DNA topoisomerase [Streptococcus caballi].	28.41	542	335	17	7	539	4	501	2e-49	191
rs:WP_036781770	DNA topoisomerase III [Pontibacillus chungwhensis].	28.70	554	362	15	7	544	6	542	2e-49	193
rs:WP_021371256	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.23	544	312	17	7	531	4	493	2e-49	191
rs:WP_042253442	topoisomerase I [Lactobacillus brevis].	28.50	586	369	19	5	563	3	565	2e-49	193
rs:WP_016381855	DNA topoisomerase III [Lactobacillus paracasei].	28.06	588	369	16	5	563	3	565	2e-49	193
rs:WP_022089074	DNA topoisomerase [Eubacterium sp. CAG:156].	28.46	622	351	24	8	553	7	610	2e-49	192
rs:WP_006627218	DNA topoisomerase [Bulleidia extructa].	29.04	544	329	18	7	539	4	501	2e-49	191
rs:WP_024866752	DNA topoisomerase [Butyrivibrio sp. FCS014].	28.77	570	351	18	7	532	6	564	2e-49	196
rs:WP_037250833	MULTISPECIES: DNA topoisomerase III, partial [Roseomonas].	26.99	552	345	14	7	531	6	526	3e-49	192
rs:WP_042398858	hypothetical protein [Clostridium sp. JCC].	29.16	559	328	18	7	539	4	520	3e-49	192
rs:WP_016085083	DNA topoisomerase III [Bacillus cereus].	28.89	585	349	21	5	554	3	555	3e-49	192
rs:WP_001094105	DNA topoisomerase III [Bacillus cereus].	28.50	579	359	21	5	554	3	555	3e-49	192
rs:WP_033797970	hypothetical protein [Bacillus mycoides].	26.61	575	365	14	4	555	1	541	3e-49	192
tr:A0A0C7GCE7_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEN79521.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEN79521.1};	28.55	599	381	18	7	590	4	570	3e-49	192
rs:WP_000259048	DNA topoisomerase III [Streptococcus agalactiae].	27.46	619	378	20	4	602	2	569	3e-49	191
rs:WP_016208465	DNA topoisomerase III [Clostridium sartagoforme].	28.47	590	363	25	5	553	4	575	3e-49	192
tr:A0A0C7R9A4_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEQ12311.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEQ12311.1};	28.48	597	384	18	7	590	4	570	3e-49	192
rs:WP_000209238	DNA topoisomerase III [Bacillus cereus].	28.48	597	336	23	5	554	3	555	3e-49	192
rs:WP_039980728	DNA topoisomerase III [Vibrio sagamiensis].	28.77	563	344	18	4	532	1	540	3e-49	193
rs:WP_022405198	DNA topoisomerase III [Prevotella sp. CAG:485].	28.37	557	343	19	7	539	2	526	3e-49	192
rs:WP_038228795	DNA topoisomerase III [Vibrio sp. ER1A].	30.05	559	342	18	4	532	1	540	3e-49	193
rs:WP_003498632	MULTISPECIES: DNA topoisomerase III [Clostridiales].	27.27	572	354	18	7	548	5	544	3e-49	192
rs:WP_029499016	DNA topoisomerase III [Kurthia huakuii].	27.92	566	361	19	7	550	5	545	3e-49	192
rs:WP_027879013	DNA topoisomerase III [Mesoflavibacter zeaxanthinifaciens].	28.47	555	348	18	8	550	5	522	3e-49	193
rs:WP_016078851	DNA topoisomerase III [Bacillus cereus].	28.72	585	350	21	5	554	3	555	3e-49	192
tr:T0XPW2_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.65	452	292	9	107	548	1	436	3e-49	191
rs:WP_022345820	DNA topoisomerase [Clostridium sp. CAG:299].	27.90	595	351	20	8	535	7	590	3e-49	192
rs:WP_038565766	DNA topoisomerase [Terribacillus aidingensis].	29.48	553	339	16	4	532	1	526	3e-49	192
rs:WP_027365920	DNA topoisomerase III, partial [Desulfotomaculum alcoholivorax].	29.14	525	333	14	7	515	5	506	3e-49	189
gpu:CP011068_1036	DNA topoisomerase [Streptococcus pyogenes]	28.75	553	319	19	7	539	6	503	3e-49	191
tr:A0A0E1SW33_HAEIF	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EDK12149.1};	27.55	519	328	16	7	494	4	505	3e-49	190
rs:WP_000186172	DNA topoisomerase III [Bacillus cereus].	29.17	593	342	18	6	556	5	561	3e-49	192
rs:WP_000779854	DNA topoisomerase [Streptococcus agalactiae].	28.60	542	334	18	7	539	4	501	3e-49	191
rs:WP_028540227	DNA topoisomerase III [Paenibacillus sp. J14].	27.79	583	343	20	5	559	3	535	3e-49	192
rs:WP_004361160	DNA topoisomerase III [Prevotella melaninogenica].	29.38	565	323	22	7	531	2	530	3e-49	191
rs:WP_040397454	DNA topoisomerase [Anaerococcus senegalensis].	28.45	566	329	20	7	551	4	514	3e-49	191
rs:WP_024639859	DNA topoisomerase III [Pseudomonas syringae].	26.93	609	392	16	4	574	1	594	3e-49	192
tr:K6KZQ0_KLEOX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.92	505	337	12	7	495	4	497	3e-49	189
rs:WP_016313465	DNA topoisomerase III [Paenibacillus barengoltzii].	27.79	583	343	20	5	559	3	535	3e-49	192
rs:WP_021427439	DNA topoisomerase III [Peptoclostridium difficile].	28.23	542	336	17	7	539	4	501	3e-49	191
rs:WP_039122908	DNA topoisomerase III [Lactobacillus ruminis].	28.62	545	324	21	7	539	5	496	3e-49	192
rs:WP_007708551	DNA topoisomerase III [[Clostridium] asparagiforme].	27.51	567	359	17	7	548	5	544	3e-49	192
rs:WP_024052236	DNA topoisomerase [Streptococcus anginosus].	27.92	616	383	18	4	603	2	572	3e-49	191
rs:WP_029321285	DNA topoisomerase [Bacillus sp. RP1137].	28.22	606	389	19	7	588	4	587	3e-49	192
rs:WP_027471632	DNA topoisomerase III [Saccharicrinis fermentans].	28.09	566	365	17	8	563	5	538	3e-49	193
rs:WP_019034962	DNA topoisomerase III [Peptoniphilus lacrimalis].	28.62	566	328	20	7	551	4	514	3e-49	191
rs:WP_037404202	MULTISPECIES: DNA topoisomerase III [Serratia].	29.53	569	352	15	7	543	4	555	3e-49	192
rs:WP_007862391	DNA topoisomerase III [[Clostridium] citroniae].	26.95	564	350	15	7	549	4	526	3e-49	192
rs:WP_024690810	DNA topoisomerase III [Pseudomonas syringae].	27.07	591	387	15	4	565	1	576	3e-49	192
rs:WP_016251036	DNA topoisomerase III [Enterococcus cecorum].	28.24	556	335	20	7	550	5	508	3e-49	192
rs:WP_000648780	DNA topoisomerase [Bacillus thuringiensis].	28.25	616	395	19	7	601	5	594	3e-49	192
rs:WP_022455370	DNA topoisomerase I [Parabacteroides sp. CAG:409].	28.46	513	323	16	8	505	16	499	3e-49	189
rs:WP_004634442	DNA topoisomerase III [Gemella morbillorum].	29.28	543	329	19	7	539	4	501	3e-49	191
rs:WP_036922967	DNA topoisomerase III [Prevotella sp. ICM33].	29.63	567	319	22	7	531	2	530	4e-49	191
rs:WP_034604312	MULTISPECIES: DNA topoisomerase III, partial [Desulfovibrio].	28.32	579	354	19	5	549	4	555	4e-49	192
rs:WP_043482912	hypothetical protein, partial [Geothrix fermentans].	26.32	608	394	15	7	579	4	592	4e-49	191
tr:A8TWU8_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.02	570	358	16	7	552	6	541	4e-49	193
rs:WP_039542348	DNA topoisomerase III [Vibrio vulnificus].	28.79	639	389	24	4	602	1	613	4e-49	192
rs:WP_046922005	DNA topoisomerase III [Lactobacillus ruminis].	28.73	543	326	20	7	539	5	496	4e-49	192
rs:WP_024855755	DNA topoisomerase III [Lactobacillus brevis].	28.47	590	364	19	5	563	3	565	4e-49	192
rs:WP_033337307	hypothetical protein, partial [Thioalkalivibrio thiocyanodenitrificans].	30.99	455	281	13	1	449	1	428	4e-49	187
rs:WP_043128703	DNA topoisomerase III, partial [Photobacterium leiognathi].	29.98	457	295	11	110	548	1	450	4e-49	190
tr:A0A0C7HUT9_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEO05722.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEO05722.1};	28.31	597	385	17	7	590	4	570	4e-49	192
rs:WP_047185446	DNA topoisomerase [Bacilli bacterium VT-13-104].	28.03	578	362	20	7	558	4	553	4e-49	192
rs:WP_016147228	DNA topoisomerase III [Butyricicoccus pullicaecorum].	27.86	560	348	16	7	549	4	524	4e-49	192
rs:WP_034288249	DNA topoisomerase [Bacillus sp. 72].	27.51	618	404	18	7	601	6	602	4e-49	192
rs:WP_042223993	DNA topoisomerase [Oceanobacillus manasiensis].	28.31	611	384	20	7	590	4	587	4e-49	192
rs:WP_016303791	DNA topoisomerase III [Lachnospiraceae bacterium A2].	28.70	554	335	17	7	539	4	518	4e-49	192
rs:WP_002369673	DNA topoisomerase [Enterococcus faecium].	29.33	583	370	18	5	563	3	567	4e-49	192
rs:WP_026831086	DNA topoisomerase III [Exiguobacterium antarcticum].	29.38	497	321	15	43	530	42	517	4e-49	192
rs:WP_017768572	DNA topoisomerase III [Streptococcus agalactiae].	28.27	626	368	24	4	603	2	572	4e-49	191
rs:WP_044188831	DNA topoisomerase III [Porphyromonas sp. COT-290 OH860].	27.34	567	357	16	7	546	2	540	4e-49	192
rs:WP_027077441	DNA topoisomerase III [Maribacter antarcticus].	28.28	548	356	16	8	550	5	520	4e-49	192
rs:WP_031598161	DNA topoisomerase III [Pseudomonas savastanoi].	26.54	633	409	18	4	598	1	615	5e-49	192
rs:WP_007658541	DNA topoisomerase III [Parabacteroides goldsteinii].	28.20	539	340	19	8	531	5	511	5e-49	192
rs:WP_014969939	DNA topoisomerase III [Exiguobacterium antarcticum].	29.38	497	321	15	43	530	42	517	5e-49	192
rs:WP_025481300	DNA topoisomerase [Enterococcus faecium].	29.85	583	367	18	5	563	3	567	5e-49	192
rs:WP_013551991	DNA topoisomerase III [Cellulophaga algicola].	28.41	535	339	16	8	531	5	506	5e-49	192
tr:A0A0C7QL11_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEP96439.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEP96439.1};	28.31	597	385	17	7	590	4	570	5e-49	192
rs:WP_047000790	DNA topoisomerase III [Clostridium beijerinckii].	28.06	588	368	25	5	553	4	575	5e-49	191
gp:HE577055_73	DNA topoisomerase III [Paenibacillus polymyxa M1]	27.84	625	396	19	4	598	1	600	5e-49	195
rs:WP_044920444	hypothetical protein [Anaerostipes hadrus].	29.22	599	365	21	9	581	6	571	5e-49	192
rs:WP_012108053	DNA topoisomerase III [Campylobacter hominis].	26.92	587	375	16	7	563	4	566	5e-49	192
rs:WP_006525975	DNA topoisomerase [Solobacterium moorei].	28.93	553	318	19	7	539	4	501	5e-49	190
rs:WP_014072880	DNA topoisomerase III [Lactobacillus ruminis].	28.47	548	331	20	7	544	5	501	5e-49	192
rs:WP_021413190	DNA topoisomerase III, partial [Peptoclostridium difficile].	29.19	596	383	17	7	590	4	572	5e-49	192
rs:WP_002589130	DNA topoisomerase III [[Clostridium] clostridioforme].	26.95	564	350	15	7	549	4	526	5e-49	192
rs:WP_033958343	DNA topoisomerase III [Psychroserpens sp. PAMC 27130].	28.62	538	336	16	8	531	5	508	5e-49	192
rs:WP_018716119	DNA topoisomerase III [Brachymonas chironomi].	28.77	584	358	23	3	550	2	563	5e-49	194
rs:WP_016185174	DNA topoisomerase III [Enterococcus sulfureus].	31.46	569	343	19	5	545	4	553	5e-49	192
rs:WP_044001639	DNA topoisomerase III [Hymenobacter swuensis].	27.05	573	360	17	4	539	1	552	5e-49	192
rs:WP_020325450	hypothetical protein, partial [Pseudomonas syringae].	26.71	569	375	14	4	543	1	556	5e-49	190
rs:WP_042775760	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	30.16	557	344	17	4	532	1	540	5e-49	191
rs:WP_024564950	DNA topoisomerase [Elizabethkingia anophelis].	29.07	571	333	17	4	550	1	523	5e-49	191
rs:WP_010632324	DNA topoisomerase III [Sporolactobacillus vineae].	28.09	566	326	19	5	546	4	512	5e-49	192
tr:A0A0A1H2H0_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.52	636	393	20	1	603	1	601	5e-49	192
tr:A0A0A8VZ19_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.48	597	384	18	7	590	4	570	5e-49	192
rs:WP_008978421	DNA topoisomerase III [Erysipelotrichaceae bacterium 5_2_54FAA].	27.05	562	365	15	5	550	3	535	6e-49	192
rs:WP_001263213	DNA topoisomerase III [Vibrio sp. RC341].	28.67	558	351	16	4	532	1	540	6e-49	192
rs:WP_005227252	DNA topoisomerase III [Enterococcus casseliflavus].	29.69	576	328	23	7	563	5	522	6e-49	191
rs:WP_003507970	DNA topoisomerase III [[Clostridium] symbiosum].	27.10	572	355	18	7	548	5	544	6e-49	192
rs:WP_001094110	DNA topoisomerase III [Staphylococcus aureus].	30.22	556	347	16	5	544	3	533	6e-49	191
rs:WP_046147493	DNA topoisomerase III [Parabacteroides goldsteinii].	28.20	539	340	19	8	531	5	511	6e-49	191
rs:WP_042133389	DNA topoisomerase III [Paenibacillus sp. FSL P4-0081].	28.29	562	335	16	7	544	5	522	6e-49	192
rs:WP_003430842	DNA topoisomerase [Peptoclostridium difficile].	29.19	596	383	17	7	590	4	572	6e-49	192
rs:WP_018361859	DNA topoisomerase III [Prevotella nanceiensis].	28.99	545	335	18	7	531	2	514	6e-49	191
rs:WP_047242158	DNA topoisomerase III [Enterococcus cecorum].	28.06	556	336	20	7	550	5	508	6e-49	191
rs:WP_041894446	DNA topoisomerase [Clostridium beijerinckii].	27.92	616	393	19	7	595	5	596	6e-49	192
rs:WP_021419380	DNA topoisomerase [Peptoclostridium difficile].	29.19	596	383	17	7	590	4	572	6e-49	192
rs:WP_021876076	DNA topoisomerase [Clostridium chauvoei].	29.01	586	366	22	5	553	4	576	6e-49	191
rs:WP_045402153	DNA topoisomerase III [Vibrio campbellii].	29.08	564	341	18	4	532	1	540	6e-49	192
rs:WP_011391892	DNA topoisomerase [Moorella thermoacetica].	31.70	489	295	12	107	578	1	467	6e-49	191
rs:WP_045348202	DNA topoisomerase III [Enterobacter cloacae].	29.35	569	353	15	7	543	4	555	6e-49	192
rs:WP_015061875	DNA topoisomerase III [Pseudomonas syringae].	27.26	609	390	16	4	574	1	594	7e-49	191
rs:WP_010496819	DNA topoisomerase III [Lactobacillus acidipiscis].	30.11	568	304	23	7	549	5	504	7e-49	191
rs:WP_003210143	DNA topoisomerase [Bacillus mycoides].	26.95	616	403	18	7	601	5	594	7e-49	191
rs:WP_008370080	DNA topoisomerase III [Coprococcus comes].	27.89	563	349	17	7	539	5	540	7e-49	192
rs:WP_001773473	DNA topoisomerase III [Escherichia coli].	29.00	569	355	15	7	543	4	555	7e-49	192
rs:WP_010802584	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	28.20	539	340	19	8	531	5	511	7e-49	191
rs:WP_012062393	DNA topoisomerase III [Alkaliphilus metalliredigens].	30.19	573	340	18	8	532	7	567	7e-49	192
rs:WP_021421652	DNA topoisomerase [Peptoclostridium difficile].	29.19	596	383	17	7	590	4	572	7e-49	192
rs:WP_001094103	DNA topoisomerase III, partial [Bacillus cereus].	28.69	596	336	23	5	554	3	555	7e-49	190
rs:WP_009263044	DNA topoisomerase III [Lachnospiraceae bacterium 9_1_43BFAA].	28.06	563	345	16	7	539	5	537	7e-49	191
rs:WP_004583756	DNA topoisomerase III [Porphyromonas gingivalis].	27.68	542	343	18	7	531	2	511	7e-49	191
rs:WP_027400099	DNA topoisomerase III [Anaerovorax odorimutans].	27.95	576	350	16	7	550	4	546	7e-49	191
rs:WP_027439694	DNA topoisomerase III [Lachnospiraceae bacterium AC2031].	28.20	617	359	24	8	554	6	608	7e-49	191
rs:WP_042959782	DNA topoisomerase [Enterococcus faecium].	29.67	583	368	17	5	563	3	567	7e-49	191
rs:WP_022269543	DNA topoisomerase [Firmicutes bacterium CAG:424].	27.58	562	355	18	7	548	5	534	7e-49	191
rs:WP_004178242	DNA topoisomerase III [Nitrosospira sp. APG3].	30.62	552	337	20	5	531	4	534	7e-49	192
rs:WP_024738311	DNA topoisomerase III [Clostridiales bacterium VE202-16].	27.27	572	354	18	7	548	5	544	7e-49	191
tr:S5W9T8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.67	583	368	17	5	563	4	568	7e-49	191
rs:WP_011053526	hypothetical protein [Haemophilus influenzae].	28.47	555	352	14	7	531	4	543	7e-49	192
rs:WP_036680927	DNA topoisomerase III [Paenibacillus sp. FSL H8-237].	28.34	561	339	17	5	544	3	521	7e-49	191
rs:WP_035604100	DNA topoisomerase III [Hylemonella gracilis].	27.85	614	368	21	5	568	3	591	7e-49	193
rs:WP_004454701	DNA topoisomerase [Peptoclostridium difficile].	29.19	596	383	17	7	590	4	572	7e-49	191
rs:WP_036764969	DNA topoisomerase [Peptostreptococcus sp. MV1].	29.10	543	330	18	7	539	4	501	7e-49	189
rs:WP_032427309	DNA topoisomerase III, partial [Klebsiella pneumoniae].	29.41	459	293	11	110	548	6	453	7e-49	189
rs:WP_002825295	DNA topoisomerase III [Oenococcus oeni].	29.20	589	361	20	5	563	3	565	8e-49	191
rs:WP_012656100	DNA topoisomerase III [Macrococcus caseolyticus].	29.00	569	356	18	5	559	3	537	8e-49	191
rs:WP_016176677	DNA topoisomerase III [Enterococcus durans].	29.25	588	362	19	5	563	3	565	8e-49	191
rs:WP_025481136	DNA topoisomerase [Enterococcus faecium].	29.50	583	369	18	5	563	3	567	8e-49	191
rs:WP_009897597	DNA topoisomerase [Peptoclostridium difficile].	29.19	596	383	17	7	590	4	572	8e-49	191
rs:WP_044755911	DNA topoisomerase [Streptococcus suis].	27.21	610	389	20	7	606	4	568	8e-49	189
rs:WP_027702332	DNA topoisomerase III [[Clostridium] mangenotii].	27.91	541	332	14	7	532	6	503	8e-49	191
rs:WP_018462451	DNA topoisomerase III [Prevotella paludivivens].	28.21	553	338	17	7	531	2	523	8e-49	191
rs:WP_037328208	DNA topoisomerase [Anaerococcus lactolyticus].	28.04	542	337	16	7	539	6	503	8e-49	189
rs:WP_000209239	DNA topoisomerase III [Bacillus cereus].	28.69	589	345	21	5	554	3	555	8e-49	191
rs:WP_006270428	DNA topoisomerase III [Streptococcus constellatus].	27.84	546	341	16	7	543	4	505	8e-49	189
rs:WP_038888830	DNA topoisomerase III [Vibrio campbellii].	29.08	564	341	18	4	532	1	540	8e-49	191
rs:WP_047342146	DNA topoisomerase III [Enterococcus cecorum].	28.24	556	335	20	7	550	5	508	8e-49	191
rs:WP_022583005	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.23	544	312	17	7	531	4	493	8e-49	189
rs:WP_026954375	DNA topoisomerase III [Algoriphagus vanfongensis].	29.01	555	350	18	7	550	2	523	8e-49	191
rs:WP_019387032	DNA topoisomerase III [Arenitalea lutea].	28.21	553	352	18	8	550	5	522	8e-49	191
rs:WP_038815648	DNA topoisomerase III [Campylobacter jejuni].	26.71	584	375	16	8	559	5	567	8e-49	191
rs:WP_027640180	DNA topoisomerase [Clostridium cadaveris].	29.23	544	312	17	7	531	4	493	8e-49	189
rs:WP_021994635	DNA topoisomerase [Sutterella wadsworthensis CAG:135].	29.35	552	342	20	5	531	4	532	8e-49	192
rs:WP_037606927	DNA topoisomerase [Streptococcus sp. CM7].	28.21	553	322	19	7	539	6	503	9e-49	189
rs:WP_008792719	DNA topoisomerase III [Coprobacillus sp. 8_2_54BFAA].	27.50	571	373	16	3	559	2	545	9e-49	191
rs:WP_022543364	DNA topoisomerase III [Bacillus infantis].	28.93	560	332	22	7	550	5	514	9e-49	191
rs:WP_011152917	hypothetical protein [Pseudomonas syringae].	26.90	591	388	15	4	565	1	576	9e-49	191
rs:WP_025839347	DNA topoisomerase III [Prevotella scopos].	29.20	565	324	22	7	531	2	530	9e-49	190
rs:WP_022036564	hypothetical protein [Roseburia sp. CAG:50].	27.12	601	373	19	8	554	7	596	9e-49	191
rs:WP_009893600	DNA topoisomerase [Peptoclostridium difficile].	29.19	596	383	17	7	590	4	572	9e-49	191
rs:WP_008754320	DNA topoisomerase [Lachnoanaerobaculum saburreum].	29.78	544	325	19	7	539	4	501	9e-49	189
rs:WP_027430564	DNA topoisomerase III [Lachnospira multipara].	26.58	602	379	18	5	554	4	594	9e-49	191
rs:WP_016200501	DNA topoisomerase III [Elizabethkingia meningoseptica].	29.15	542	332	18	8	531	5	512	9e-49	191
rs:WP_021943206	DNA topoisomerase [Clostridium sp. CAG:264].	28.43	591	365	20	8	554	6	582	9e-49	191
rs:WP_019948955	hypothetical protein [Hymenobacter aerophilus].	27.16	626	389	22	7	590	2	602	9e-49	192
rs:WP_039375166	DNA topoisomerase III, partial [Mumia flava].	28.83	600	367	21	7	577	6	574	9e-49	190
rs:WP_002305772	DNA topoisomerase [Enterococcus faecium].	29.67	583	368	17	5	563	3	567	9e-49	191
rs:WP_038486864	DNA topoisomerase III, partial [Halomonas campaniensis].	31.06	396	255	11	200	584	6	394	9e-49	187
rs:WP_016624844	DNA topoisomerase [Enterococcus faecalis].	29.02	579	376	15	5	563	3	566	9e-49	191
rs:WP_005876033	topoisomerase [Enterococcus durans].	29.25	588	362	19	5	563	3	565	9e-49	191
rs:WP_000294907	DNA topoisomerase III, partial [Salmonella enterica].	30.89	395	254	10	170	552	14	401	9e-49	188
rs:WP_045422785	DNA topoisomerase III [Vibrio jasicida].	29.27	550	350	15	8	532	5	540	1e-48	191
rs:WP_015867941	DNA topoisomerase III [Variovorax paradoxus].	29.08	612	362	25	5	568	3	590	1e-48	193
rs:WP_021422494	DNA topoisomerase [Peptoclostridium difficile].	29.19	596	383	17	7	590	4	572	1e-48	191
rs:WP_046152240	DNA topoisomerase III [Burkholderia andropogonis].	28.60	563	363	17	7	550	6	548	1e-48	192
rs:WP_024903475	DNA topoisomerase III [Burkholderia andropogonis].	28.60	563	363	17	7	550	6	548	1e-48	192
rs:WP_013056649	DNA topoisomerase [Bacillus megaterium].	27.95	619	400	19	7	601	4	600	1e-48	191
rs:WP_026752833	DNA topoisomerase III [Sediminibacter sp. Hel_I_10].	28.26	552	356	16	8	550	5	525	1e-48	191
rs:WP_021406476	DNA topoisomerase [Peptoclostridium difficile].	29.19	596	383	17	7	590	4	572	1e-48	191
rs:WP_026977380	DNA topoisomerase III [Flavobacterium tegetincola].	29.11	553	347	18	8	550	5	522	1e-48	191
rs:WP_009229076	DNA topoisomerase III [Prevotella sp. oral taxon 299].	28.88	547	333	19	7	531	2	514	1e-48	191
rs:WP_003436835	MULTISPECIES: DNA topoisomerase III [Pseudomonas syringae group].	26.23	591	392	14	4	565	1	576	1e-48	191
rs:WP_011112497	DNA topoisomerase III [Nitrosomonas europaea].	28.77	577	347	20	7	550	6	551	1e-48	191
rs:WP_029296993	DNA topoisomerase III [Chryseobacterium hispalense].	30.33	544	325	20	8	531	5	514	1e-48	191
rs:WP_006073986	DNA topoisomerase III [Vibrio shilonii].	29.87	559	343	18	4	532	1	540	1e-48	191
rs:WP_012552651	MULTISPECIES: topoisomerase III [Bacillus cereus group].	30.63	555	336	19	5	531	4	537	1e-48	191
rs:WP_022744481	DNA topoisomerase 3 [Clostridium saccharobutylicum].	28.17	600	379	18	7	579	5	579	1e-48	191
tr:A0A0C7H255_CLOSO	SubName: Full=TopB protein {ECO:0000313|EMBL:CEN88271.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEN88271.1};	28.48	597	384	18	7	590	4	570	1e-48	191
rs:WP_000259046	DNA topoisomerase III [Streptococcus agalactiae].	27.38	621	378	21	4	602	2	571	1e-48	189
rs:WP_009461407	DNA topoisomerase III [Lachnospiraceae bacterium 2_1_46FAA].	28.29	562	352	19	7	548	5	535	1e-48	191
rs:WP_009168861	DNA topoisomerase [Clostridium sp. DL-VIII].	27.91	602	379	19	7	579	5	580	1e-48	191
rs:WP_042350292	DNA topoisomerase III, partial [Escherichia coli].	30.89	395	254	10	170	552	4	391	1e-48	187
rs:WP_016728792	DNA topoisomerase [Peptoclostridium difficile].	29.19	596	383	17	7	590	4	572	1e-48	191
rs:WP_024397233	DNA topoisomerase [Streptococcus suis].	28.75	553	319	18	7	539	4	501	1e-48	189
rs:WP_020999707	DNA topoisomerase III [Streptococcus anginosus].	28.91	543	331	18	7	539	4	501	1e-48	189
rs:WP_047340951	DNA topoisomerase III [Enterococcus cecorum].	28.06	556	336	20	7	550	5	508	1e-48	191
rs:WP_036729935	DNA topoisomerase III, partial [Patulibacter minatonensis].	26.37	641	401	21	5	597	4	621	1e-48	191
rs:WP_026573203	DNA topoisomerase III [Bacillus sp. UNC438CL73TsuS30].	28.39	546	346	15	7	530	4	526	1e-48	191
rs:WP_016171207	DNA topoisomerase III [Enterococcus faecium].	29.50	583	369	17	5	563	3	567	1e-48	190
rs:WP_028979020	DNA topoisomerase III [Sporocytophaga myxococcoides].	28.70	540	335	18	8	531	5	510	1e-48	191
rs:WP_021413946	DNA topoisomerase [Peptoclostridium difficile].	29.19	596	383	17	7	590	4	572	1e-48	191
rs:WP_021866241	DNA topoisomerase [Eubacterium sp. CAG:86].	27.17	600	373	20	5	553	4	590	1e-48	190
rs:WP_045488834	DNA topoisomerase [Bacillus sp. TS-2].	28.11	555	351	17	7	539	4	532	1e-48	191
rs:WP_045417592	DNA topoisomerase III [Vibrio owensii].	29.08	564	341	17	4	532	1	540	1e-48	191
rs:WP_028977379	DNA topoisomerase III [Sporolactobacillus terrae].	28.14	565	334	19	7	548	6	521	1e-48	191
rs:WP_009530028	DNA topoisomerase III [Peptostreptococcaceae bacterium CM5].	28.38	613	380	20	7	607	6	571	1e-48	189
rs:WP_044297029	DNA topoisomerase III [Robinsoniella peoriensis].	27.84	564	356	17	7	548	5	539	1e-48	191
rs:WP_003426113	DNA topoisomerase III [Peptoclostridium difficile].	28.04	542	337	17	7	539	4	501	1e-48	189
rs:WP_046150268	DNA topoisomerase III [Parabacteroides sp. HGS0025].	27.97	547	331	19	8	531	5	511	1e-48	191
rs:WP_015245972	DNA topoisomerase III [Singulisphaera acidiphila].	30.04	566	343	22	4	553	1	529	1e-48	191
rs:WP_007392113	DNA topoisomerase [Megasphaera sp. UPII 135-E].	28.57	553	320	19	7	539	6	503	1e-48	189
rs:WP_018377913	DNA topoisomerase III [Streptococcus ovis].	26.98	619	383	20	4	602	2	571	1e-48	189
rs:WP_039345333	DNA topoisomerase III [Chryseobacterium solincola].	29.55	538	333	18	8	531	5	510	1e-48	191
rs:WP_002834103	DNA topoisomerase III, partial [Campylobacter coli].	26.54	584	376	16	8	559	5	567	1e-48	190
rs:WP_044423982	DNA topoisomerase III [Pseudomonas savastanoi].	27.55	588	382	16	7	565	4	576	1e-48	191
rs:WP_021396176	DNA topoisomerase [Peptoclostridium difficile].	29.19	596	383	17	7	590	4	572	1e-48	191
rs:WP_016439735	DNA topoisomerase III [Coprococcus sp. HPP0074].	27.89	563	346	16	7	539	5	537	1e-48	191
rs:WP_036978530	DNA topoisomerase, partial [Pseudobutyrivibrio sp. MD2005].	28.00	600	368	18	7	554	6	593	1e-48	191
tr:R3KM90_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.67	583	368	17	5	563	4	568	1e-48	191
rs:WP_016223842	DNA topoisomerase III [Lachnospiraceae bacterium 3-2].	28.09	566	342	15	7	549	4	527	1e-48	191
rs:WP_018708124	DNA topoisomerase [Bacillus fordii].	27.50	629	395	20	4	598	2	603	1e-48	191
rs:WP_021013085	DNA topoisomerase 3 [Variovorax paradoxus].	28.92	612	363	25	5	568	4	591	1e-48	192
rs:WP_035968559	DNA topoisomerase III [Burkholderia grimmiae].	28.20	578	382	16	7	568	6	566	1e-48	192
rs:WP_025480081	DNA topoisomerase [Enterococcus faecium].	29.67	583	368	17	5	563	3	567	1e-48	191
rs:WP_026905925	DNA topoisomerase [Paucisalibacillus globulus].	28.52	596	381	19	7	579	4	577	1e-48	191
tr:A0A0E1ZME0_CAMJU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EIB53379.1}; Flags: Fragment;	26.54	584	376	16	8	559	5	567	1e-48	190
rs:WP_021403859	DNA topoisomerase [Peptoclostridium difficile].	29.19	596	383	17	7	590	4	572	1e-48	191
rs:WP_005866302	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	28.01	539	341	17	8	531	5	511	1e-48	190
rs:WP_011246962	DNA topoisomerase [Bacillus clausii].	28.76	605	382	20	7	590	4	580	1e-48	191
rs:WP_005657222	DNA topoisomerase III [Bacteroides stercoris].	27.43	565	350	19	7	531	2	546	1e-48	191
rs:WP_045171904	DNA topoisomerase [Enterococcus faecium].	29.67	583	368	17	5	563	3	567	1e-48	191
rs:WP_036862877	DNA topoisomerase III [Prevotella melaninogenica].	29.45	567	320	22	7	531	2	530	1e-48	189
rs:WP_002687992	DNA topoisomerase III [Bergeyella zoohelcum].	29.41	544	329	19	8	531	5	513	2e-48	190
rs:WP_033602639	DNA topoisomerase III [Enterococcus faecium].	29.27	574	333	24	7	563	5	522	2e-48	190
rs:WP_031500043	DNA topoisomerase III [Vibrio parahaemolyticus].	30.16	557	344	17	4	532	1	540	2e-48	191
rs:WP_029699126	DNA topoisomerase III [Clostridium sp. Ade.TY].	28.79	587	364	21	8	554	7	579	2e-48	190
rs:WP_014216307	DNA topoisomerase III [Pediococcus claussenii].	28.73	623	394	21	5	603	3	599	2e-48	190
rs:WP_021740058	DNA topoisomerase [Eubacterium ramulus].	26.96	601	374	19	8	554	7	596	2e-48	190
rs:WP_009906449	DNA topoisomerase III [Peptoclostridium difficile].	27.86	542	338	17	7	539	4	501	2e-48	189
rs:WP_025489788	DNA topoisomerase III [Clostridiales bacterium VE202-27].	26.88	625	370	20	7	554	6	620	2e-48	190
rs:WP_002370882	DNA topoisomerase, partial [Enterococcus faecium].	28.28	541	354	14	42	563	26	551	2e-48	188
rs:WP_002809261	DNA topoisomerase III, partial [Campylobacter coli].	26.54	584	376	16	8	559	5	567	2e-48	189
rs:WP_044394496	DNA topoisomerase III [Bacillus subterraneus].	27.82	611	374	23	7	602	5	563	2e-48	190
rs:WP_002325542	DNA topoisomerase III [Enterococcus faecium].	29.67	583	368	17	5	563	4	568	2e-48	191
rs:WP_029378515	DNA topoisomerase III [Staphylococcus xylosus].	26.42	564	376	18	7	559	5	540	2e-48	190
rs:WP_043037586	DNA topoisomerase, partial [Streptococcus equi].	28.99	552	319	17	7	539	4	501	2e-48	188
rs:WP_025479250	DNA topoisomerase [Enterococcus faecium].	29.67	583	368	17	5	563	3	567	2e-48	191
rs:WP_040175367	hypothetical protein, partial [Phaeobacter sp. S26].	28.50	579	330	19	1	541	1	533	2e-48	190
rs:WP_004281998	conjugal transfer protein TraE [Acinetobacter lwoffii].	25.95	605	406	14	7	585	5	593	2e-48	190
rs:WP_045461521	DNA topoisomerase III [Sporocytophaga myxococcoides].	28.89	540	334	18	8	531	5	510	2e-48	191
rs:WP_042253463	topoisomerase I [Lactobacillus brevis].	27.65	633	388	21	5	603	3	599	2e-48	190
rs:WP_022129902	DNA topoisomerase III [Bacteroides sp. CAG:530].	28.11	555	323	20	7	531	2	510	2e-48	190
rs:WP_043019033	DNA topoisomerase III, partial [Campylobacter jejuni].	26.54	584	376	16	8	559	5	567	2e-48	189
rs:WP_016284646	DNA topoisomerase III [Lachnospiraceae bacterium A4].	28.70	568	336	18	7	549	4	527	2e-48	190
rs:WP_028784638	DNA topoisomerase III [Thalassobacillus devorans].	28.67	565	356	17	7	548	6	546	2e-48	190
rs:WP_012960832	DNA topoisomerase III [Bacillus pseudofirmus].	29.21	558	351	18	5	548	4	531	2e-48	190
rs:WP_016628767	DNA topoisomerase [Enterococcus faecium].	29.67	583	368	17	5	563	3	567	2e-48	190
rs:WP_041095836	topoisomerase I [Lactobacillus hokkaidonensis].	27.53	632	390	20	5	603	3	599	2e-48	190
rs:WP_032597331	DNA topoisomerase III, partial [Campylobacter jejuni].	26.80	582	377	16	8	559	5	567	2e-48	189
rs:WP_019331405	DNA topoisomerase III [Pseudomonas syringae].	26.57	591	390	15	4	565	1	576	2e-48	190
rs:WP_028608020	DNA topoisomerase III [Olleya sp. VCSM12].	27.64	550	359	17	8	550	5	522	2e-48	191
rs:WP_039680621	DNA topoisomerase [Terrisporobacter othiniensis].	28.57	595	388	16	7	590	4	572	2e-48	190
rs:WP_037990282	DNA topoisomerase III [Tepidiphilus margaritifer].	28.19	564	363	20	7	550	6	547	2e-48	191
rs:WP_009511995	DNA topoisomerase III [Opitutaceae bacterium TAV5].	29.55	616	363	22	7	577	5	594	2e-48	192
rs:WP_033606890	DNA topoisomerase III [Enterococcus faecium].	29.27	574	333	24	7	563	5	522	2e-48	190
rs:WP_005429239	DNA topoisomerase III [Sutterella wadsworthensis].	29.17	552	343	20	5	531	4	532	2e-48	191
rs:WP_037029964	DNA topoisomerase [Psychrilyobacter atlanticus].	30.53	583	320	26	7	561	4	529	2e-48	190
rs:WP_003660153	DNA topoisomerase III [Lactobacillus paracasei].	28.82	583	371	18	5	563	3	565	2e-48	190
rs:WP_019241916	DNA topoisomerase [Bacillus massilioanorexius].	26.76	598	389	18	7	582	5	575	2e-48	190
rs:WP_038816692	DNA topoisomerase III [Campylobacter jejuni].	26.71	584	375	16	8	559	5	567	2e-48	190
rs:WP_027094431	DNA topoisomerase III [Cohnella thermotolerans].	26.88	640	392	19	5	601	3	609	2e-48	191
rs:WP_027294681	DNA topoisomerase III [Robinsoniella sp. KNHs210].	27.84	564	356	17	7	548	5	539	2e-48	190
rs:WP_044310701	DNA topoisomerase III [Pseudomonas syringae].	27.38	588	383	15	7	565	4	576	2e-48	190
rs:WP_024269754	DNA topoisomerase III [Escherichia coli].	28.54	459	304	10	7	452	4	451	2e-48	186
rs:WP_016289059	DNA topoisomerase III [Lachnospiraceae bacterium 3-1].	27.18	574	339	19	7	539	5	540	2e-48	190
rs:WP_022312971	DNA topoisomerase [Clostridium sp. CAG:91].	26.84	585	360	17	7	532	6	581	2e-48	190
tr:G5GKW0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.04	542	337	16	7	539	21	518	2e-48	189
rs:WP_021434765	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.23	544	312	17	7	531	4	493	2e-48	188
rs:WP_016475275	DNA topoisomerase III [Sutterella wadsworthensis].	29.35	552	342	20	5	531	4	532	2e-48	191
rs:WP_038501299	DNA topoisomerase III [Basilea psittacipulmonis].	29.32	556	350	17	3	534	2	538	2e-48	191
rs:WP_033585993	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	2e-48	190
rs:WP_025477734	DNA topoisomerase [Enterococcus faecium].	29.50	583	369	17	5	563	3	567	2e-48	190
rs:WP_009537904	MULTISPECIES: DNA topoisomerase [Lachnospiraceae].	28.93	553	318	18	7	539	4	501	2e-48	188
rs:WP_043019247	DNA topoisomerase III, partial [Campylobacter jejuni].	26.54	584	376	16	8	559	5	567	2e-48	189
rs:WP_045216857	hypothetical protein, partial [Desulfobulbus alkaliphilus].	28.96	587	373	17	7	569	8	574	2e-48	189
rs:WP_027821235	DNA topoisomerase III [Lactobacillus plantarum].	28.73	623	394	21	5	603	3	599	2e-48	190
rs:WP_043020510	DNA topoisomerase III, partial [Campylobacter jejuni].	26.54	584	376	16	8	559	5	567	2e-48	189
rs:WP_000209236	DNA topoisomerase III [Bacillus cereus].	28.64	597	335	23	5	554	3	555	2e-48	190
rs:WP_000542403	topoisomerase III [Bacillus cereus].	30.45	555	337	19	5	531	4	537	2e-48	190
rs:WP_021640469	DNA topoisomerase [[Clostridium] symbiosum].	27.10	572	355	18	7	548	5	544	2e-48	190
rs:WP_021635830	DNA topoisomerase III [Clostridium sp. KLE 1755].	26.88	625	370	20	7	554	6	620	2e-48	190
rs:WP_021425657	DNA topoisomerase [Peptoclostridium difficile].	29.03	596	384	17	7	590	4	572	2e-48	190
rs:WP_028290036	DNA topoisomerase III [Olleya sp. VCSA23].	27.45	550	360	17	8	550	5	522	2e-48	190
rs:WP_036656744	DNA topoisomerase III, partial [Paenibacillus larvae].	26.92	613	390	18	5	590	3	584	2e-48	190
rs:WP_025188549	DNA topoisomerase [Enterococcus faecalis].	28.39	553	321	19	7	539	6	503	2e-48	188
rs:WP_025789708	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	564	341	18	4	532	1	540	2e-48	190
rs:WP_034872068	DNA topoisomerase III [Enterococcus faecium].	29.51	576	329	23	7	563	5	522	2e-48	190
rs:WP_033624242	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	2e-48	190
rs:WP_016090159	DNA topoisomerase III [Bacillus cereus].	28.69	596	336	23	5	554	3	555	2e-48	190
rs:WP_016289142	DNA topoisomerase III [Lachnospiraceae bacterium 3-1].	28.26	552	339	16	7	539	4	517	2e-48	190
rs:WP_007789451	DNA topoisomerase III [Peptostreptococcus stomatis].	28.29	608	397	16	7	599	4	587	2e-48	190
rs:WP_044013192	DNA topoisomerase III [Hymenobacter sp. APR13].	27.05	573	360	17	4	539	1	552	2e-48	191
rs:WP_011861544	DNA topoisomerase [Peptoclostridium difficile].	29.03	596	384	17	7	590	4	572	2e-48	190
rs:WP_002314426	DNA topoisomerase [Enterococcus faecium].	29.50	583	369	17	5	563	3	567	2e-48	190
rs:WP_040191961	DNA topoisomerase [Clostridium sp. CL-6].	26.97	634	389	20	7	590	5	614	2e-48	190
rs:WP_022618531	DNA topoisomerase type IA [Peptoclostridium difficile].	29.03	596	384	17	7	590	4	572	2e-48	190
rs:WP_032461281	DNA topoisomerase [Streptococcus pyogenes].	28.39	553	321	19	7	539	6	503	2e-48	188
tr:D4C6M5_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.63	567	360	16	1	549	1	529	2e-48	190
rs:WP_008403089	DNA topoisomerase III [Clostridium sp. L2-50].	28.21	592	365	19	8	554	6	582	2e-48	189
rs:WP_028900129	DNA topoisomerase III [Prevotella sp. HJM029].	29.22	551	334	18	7	531	2	522	2e-48	189
rs:WP_038182308	DNA topoisomerase III [Viridibacillus arenosi].	27.37	559	372	16	3	544	2	543	2e-48	190
rs:WP_029306833	DNA topoisomerase III [Cupriavidus metallidurans].	28.33	593	382	17	7	577	6	577	2e-48	191
rs:WP_011517984	DNA topoisomerase III [Cupriavidus metallidurans].	28.33	593	382	17	7	577	6	577	2e-48	191
rs:WP_033696774	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	2e-48	189
rs:WP_036972697	DNA topoisomerase III, partial [Providencia alcalifaciens].	29.32	440	290	10	107	530	1	435	2e-48	188
rs:WP_003038090	DNA topoisomerase [Streptococcus anginosus].	28.23	542	340	15	5	539	3	502	2e-48	188
rs:WP_033643829	MULTISPECIES: DNA topoisomerase III [Enterococcus].	29.27	574	333	24	7	563	5	522	3e-48	189
rs:WP_042749367	topoisomerase I [Lactobacillus brevis].	28.79	587	366	18	5	563	3	565	3e-48	190
rs:WP_016286472	DNA topoisomerase III [Lachnospiraceae bacterium 3-1].	28.21	631	357	25	8	554	7	625	3e-48	190
rs:WP_022827355	DNA topoisomerase III [Flavobacterium antarcticum].	29.73	555	341	19	8	550	5	522	3e-48	190
rs:WP_044935049	DNA topoisomerase, partial [Pseudobutyrivibrio sp. LB2011].	28.09	598	370	18	7	554	6	593	3e-48	190
rs:WP_039106709	topoisomerase I [Lactobacillus brevis].	28.79	587	366	18	5	563	3	565	3e-48	190
rs:WP_016661811	DNA topoisomerase III [Bacteroides stercoris].	27.43	565	350	19	7	531	2	546	3e-48	190
rs:WP_047200380	DNA topoisomerase [Streptococcus agalactiae].	28.36	543	334	17	7	539	4	501	3e-48	188
rs:WP_002467740	DNA topoisomerase III [Staphylococcus epidermidis].	27.57	526	336	11	7	519	5	498	3e-48	187
rs:WP_025818807	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	564	341	18	4	532	1	540	3e-48	190
rs:WP_023180744	topoisomerase [Salmonella enterica].	26.75	587	379	14	7	564	5	569	3e-48	190
rs:WP_021953303	DNA topoisomerase [Eubacterium sp. CAG:161].	27.04	625	367	21	5	553	4	615	3e-48	189
rs:WP_007360327	DNA topoisomerase III [Opitutaceae bacterium TAV1].	29.40	619	363	22	7	577	5	597	3e-48	191
rs:WP_021422759	DNA topoisomerase III family protein [Peptoclostridium difficile].	29.23	544	312	17	7	531	4	493	3e-48	188
rs:WP_038851175	DNA topoisomerase III, partial [Campylobacter coli].	26.54	584	376	16	8	559	5	567	3e-48	189
rs:WP_025480102	DNA topoisomerase [Enterococcus faecium].	29.67	583	368	17	5	563	3	567	3e-48	190
rs:WP_038834218	DNA topoisomerase III [Campylobacter coli].	26.54	584	376	16	8	559	5	567	3e-48	190
tr:J6BME1_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.39	553	321	19	7	539	42	539	3e-48	189
rs:WP_024093897	DNA topoisomerase 3 [Paenibacillus larvae].	26.92	613	390	18	5	590	3	584	3e-48	190
rs:WP_033655186	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	3e-48	189
rs:WP_047199200	DNA topoisomerase [Streptococcus agalactiae].	28.39	553	321	19	7	539	6	503	3e-48	188
rs:WP_042597590	DNA topoisomerase [Bacillus thuringiensis].	28.08	616	396	19	7	601	5	594	3e-48	189
rs:WP_013264979	DNA topoisomerase III [Prevotella melaninogenica].	29.63	567	319	22	7	531	2	530	3e-48	189
rs:WP_024379017	DNA topoisomerase [Streptococcus suis].	28.80	552	320	18	7	539	4	501	3e-48	188
rs:WP_027446336	DNA topoisomerase III [Pontibacillus marinus].	29.86	566	348	19	7	548	6	546	3e-48	189
rs:WP_026624425	DNA topoisomerase [Eggerthia catenaformis].	29.06	554	316	19	7	539	4	501	3e-48	188
rs:WP_042396023	DNA topoisomerase [Clostridium sp. JCC].	28.53	617	384	19	7	590	5	597	3e-48	190
rs:WP_045492443	DNA topoisomerase III [Vibrio sp. 151112A].	28.72	564	343	18	4	532	1	540	3e-48	190
rs:WP_028728532	DNA topoisomerase III [Parabacteroides gordonii].	27.97	547	331	19	8	531	5	511	3e-48	189
tr:R3HW91_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.67	583	368	17	5	563	4	568	3e-48	190
rs:WP_016097322	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	28.67	579	358	20	5	554	3	555	3e-48	189
rs:WP_042362257	DNA topoisomerase III [Staphylococcus xylosus].	26.42	564	376	18	7	559	5	540	3e-48	189
rs:WP_011886436	MULTISPECIES: DNA topoisomerase III [Burkholderia].	28.16	561	368	15	7	550	6	548	3e-48	191
rs:WP_027424895	DNA topoisomerase III [Lachnospiraceae bacterium NC2004].	26.59	598	369	19	5	547	4	586	3e-48	189
rs:WP_026706744	DNA topoisomerase III [Flavobacterium frigidarium].	29.11	553	347	18	8	550	5	522	3e-48	190
tr:W2E6N4_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.92	613	390	18	5	590	3	584	3e-48	190
rs:WP_003445085	DNA topoisomerase III [Clostridium pasteurianum].	28.46	615	387	20	1	590	1	587	3e-48	189
rs:WP_040883080	DNA topoisomerase [Johnsonella ignava].	28.10	541	336	16	8	539	1	497	3e-48	187
rs:WP_017511104	MULTISPECIES: DNA topoisomerase III [Cupriavidus].	28.33	593	382	17	7	577	6	577	3e-48	191
rs:WP_042519962	MULTISPECIES: DNA topoisomerase III [Prevotella].	28.18	550	336	17	7	531	2	517	3e-48	189
rs:WP_008642749	DNA topoisomerase III [Cupriavidus sp. HMR-1].	28.33	593	382	17	7	577	6	577	3e-48	191
rs:WP_014215559	DNA topoisomerase III [Pediococcus claussenii].	28.81	611	360	22	7	595	6	563	3e-48	189
rs:WP_033426626	DNA topoisomerase III, partial [Salinicoccus albus].	31.71	451	266	16	116	549	4	429	3e-48	188
rs:WP_016322370	DNA topoisomerase III [Oscillibacter sp. 1-3].	28.52	568	337	17	7	549	4	527	3e-48	189
rs:WP_008376150	DNA topoisomerase III [Enterococcus sp. C1].	29.34	576	330	23	7	563	5	522	3e-48	189
rs:WP_004063538	DNA topoisomerase III [Eubacterium plexicaudatum].	27.46	568	350	16	3	548	2	529	3e-48	189
rs:WP_015555481	DNA topoisomerase [Taylorella equigenitalis].	29.25	571	356	17	3	543	2	554	3e-48	190
rs:WP_035881171	DNA topoisomerase III [Cupriavidus metallidurans].	28.33	593	382	17	7	577	6	577	3e-48	191
rs:WP_019109223	MULTISPECIES: DNA topoisomerase III [Campylobacter].	26.54	584	376	16	8	559	5	567	3e-48	189
rs:WP_021671158	DNA topoisomerase III [Prevotella sp. F0091].	28.60	556	339	19	7	531	2	530	3e-48	188
rs:WP_045470857	DNA topoisomerase III [Burkholderiales bacterium GJ-E10].	27.49	593	366	17	1	550	1	572	3e-48	190
rs:WP_021421870	DNA topoisomerase III [Peptoclostridium difficile].	28.04	542	337	17	7	539	4	501	3e-48	187
rs:WP_018357668	DNA topoisomerase III [Porphyromonas levii].	27.79	565	360	18	8	555	5	538	3e-48	188
rs:WP_025480889	DNA topoisomerase III [Enterococcus faecium].	29.16	583	371	17	5	563	3	567	3e-48	189
rs:WP_022517670	DNA topoisomerase [Roseburia sp. CAG:100].	27.15	593	369	18	7	550	6	584	3e-48	192
rs:WP_025481655	DNA topoisomerase [Enterococcus faecium].	29.67	583	368	17	5	563	3	567	3e-48	189
rs:WP_011968211	DNA topoisomerase [Clostridium beijerinckii].	27.76	616	394	19	7	595	5	596	3e-48	189
tr:S4E1Q5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.67	583	368	17	5	563	4	568	3e-48	189
rs:WP_034865743	DNA topoisomerase III [Enterococcus durans].	27.40	562	331	18	7	550	5	507	4e-48	189
rs:WP_046427909	hypothetical protein [Burkholderia vietnamiensis].	27.26	543	366	14	7	530	7	539	4e-48	189
rs:WP_027376452	DNA topoisomerase III [Chryseobacterium palustre].	29.34	542	332	18	8	531	5	513	4e-48	189
rs:WP_036878228	DNA topoisomerase III [Prevotella oryzae].	28.91	550	329	18	7	531	2	514	4e-48	189
rs:WP_033651462	DNA topoisomerase III [Enterococcus faecium].	28.92	574	335	23	7	563	5	522	4e-48	189
rs:WP_044393261	DNA topoisomerase III [Bacillus subterraneus].	27.01	559	370	14	4	544	1	539	4e-48	189
rs:WP_034720218	DNA topoisomerase III [Chryseobacterium antarcticum].	30.29	548	323	21	7	531	2	513	4e-48	189
rs:WP_002586545	DNA topoisomerase III [[Clostridium] clostridioforme].	26.98	567	352	16	7	549	4	532	4e-48	189
rs:WP_039861625	DNA topoisomerase III [Lachnospiraceae bacterium 6_1_37FAA].	27.71	563	347	16	7	539	5	537	4e-48	189
tr:C7X8X1_9PORP	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEU51650.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EEU51650.1};	27.83	539	342	17	8	531	16	522	4e-48	189
rs:WP_005232250	DNA topoisomerase III [Enterococcus casseliflavus].	29.34	576	330	23	7	563	5	522	4e-48	189
tr:A6LCM5_PARD8	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:ABR43439.1};	27.83	539	342	17	8	531	6	512	4e-48	189
rs:WP_036609206	DNA topoisomerase III [Oribacterium sp. P6A1].	26.57	621	387	19	7	568	5	615	4e-48	189
rs:WP_002826426	DNA topoisomerase III, partial [Campylobacter coli].	26.70	588	370	17	8	559	5	567	4e-48	189
rs:WP_022317548	MULTISPECIES: DNA topoisomerase III [Prevotella].	28.18	550	336	17	7	531	2	517	4e-48	189
rs:WP_035765999	DNA topoisomerase [Butyrivibrio sp. NC2002].	29.56	565	349	17	7	532	6	560	4e-48	192
rs:WP_044079817	DNA topoisomerase III [Prevotella sp. P4-65].	28.18	550	336	17	7	531	2	517	4e-48	189
rs:WP_035916419	DNA topoisomerase [Fusobacterium necrophorum].	28.83	555	320	18	5	539	3	502	4e-48	187
rs:WP_032469697	DNA topoisomerase III, partial [Vibrio cholerae].	29.10	457	273	12	116	539	7	445	4e-48	187
rs:WP_022233498	DNA topoisomerase III [Bacteroides sp. CAG:443].	28.39	539	342	17	7	531	2	510	4e-48	189
rs:WP_018227575	DNA topoisomerase III [Methyloversatilis universalis].	28.80	552	347	18	7	531	6	538	4e-48	190
rs:WP_002822851	DNA topoisomerase III, partial [Campylobacter coli].	26.37	584	377	16	8	559	5	567	4e-48	188
tr:E9RWM8_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.71	563	347	16	7	539	16	548	4e-48	189
rs:WP_039257512	DNA topoisomerase III [Clostridium botulinum].	28.27	566	351	22	8	532	7	558	4e-48	189
rs:WP_044679057	DNA topoisomerase [Streptococcus suis].	28.75	553	319	19	7	539	4	501	4e-48	187
rs:WP_032595977	DNA topoisomerase III, partial [Campylobacter jejuni].	26.63	582	378	16	8	559	5	567	4e-48	189
rs:WP_033607115	DNA topoisomerase, partial [Enterococcus faecalis].	29.32	556	362	17	5	544	3	543	4e-48	188
tr:D2MXM3_CAMJU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFC32963.1};	26.54	584	376	16	8	559	5	567	4e-48	189
rs:WP_007201190	DNA topoisomerase III [Fictibacillus macauensis].	27.68	625	396	20	7	601	4	602	4e-48	189
rs:WP_005858139	DNA topoisomerase III [Parabacteroides distasonis].	27.83	539	342	17	8	531	5	511	4e-48	189
rs:WP_029800262	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	29.15	470	302	13	8	459	6	462	4e-48	186
rs:WP_033606645	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	4e-48	189
rs:WP_015592305	DNA topoisomerase III [Bacillus sp. 1NLA3E].	29.21	541	313	17	5	527	3	491	4e-48	189
rs:WP_002339105	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	4e-48	189
rs:WP_022191868	hypothetical protein [Parabacteroides sp. CAG:2].	27.83	539	342	17	8	531	5	511	4e-48	189
rs:WP_017211802	MULTISPECIES: DNA topoisomerase [Clostridium].	27.76	616	394	19	7	595	5	596	4e-48	189
rs:WP_035933687	DNA topoisomerase III [Burkholderia glathei].	27.63	579	384	15	7	568	6	566	4e-48	190
rs:WP_015639749	DNA topoisomerase III [Lactobacillus plantarum].	29.16	583	369	19	5	563	3	565	4e-48	189
rs:WP_041142920	topoisomerase I, partial [Lactobacillus plantarum].	29.16	583	369	19	5	563	3	565	4e-48	189
rs:WP_002872081	DNA topoisomerase III, partial [Campylobacter jejuni].	26.37	584	377	16	8	559	5	567	4e-48	188
rs:WP_031909704	DNA topoisomerase III, partial [Staphylococcus aureus].	27.78	522	332	16	7	515	5	494	4e-48	186
rs:WP_021002848	DNA topoisomerase [Streptococcus intermedius].	28.80	552	320	18	7	539	4	501	4e-48	187
rs:WP_046811118	topoisomerase I [Lactobacillus plantarum].	28.67	586	368	21	5	563	3	565	4e-48	189
rs:WP_013104829	DNA topoisomerase III [Thiomonas arsenitoxydans].	28.86	596	371	21	3	568	2	574	4e-48	190
rs:WP_002304230	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	4e-48	189
rs:WP_044322475	DNA topoisomerase III, partial [Pseudomonas amygdali].	26.71	629	405	18	8	598	5	615	4e-48	188
rs:WP_004308745	MULTISPECIES: DNA topoisomerase I [Bacteroides].	29.09	574	345	20	4	552	1	537	4e-48	189
rs:WP_013964628	DNA topoisomerase III [Nitrosomonas sp. Is79A3].	28.82	569	365	16	3	550	2	551	5e-48	190
rs:WP_040259218	DNA topoisomerase III [Pseudomonas sp. CB1].	26.41	640	403	19	4	598	1	617	5e-48	189
rs:WP_000542404	MULTISPECIES: topoisomerase III [Bacillus cereus group].	30.45	555	337	19	5	531	4	537	5e-48	189
rs:WP_033626145	DNA topoisomerase [Enterococcus faecalis].	28.88	554	337	17	7	550	4	510	5e-48	187
rs:WP_008774235	DNA topoisomerase III [Bacteroides sp. 2_1_33B].	27.83	539	342	17	8	531	5	511	5e-48	189
rs:WP_044544965	DNA topoisomerase III [Parabacteroides distasonis].	27.83	539	342	17	8	531	5	511	5e-48	189
rs:WP_034470315	DNA topoisomerase III [Burkholderia zhejiangensis].	28.18	582	377	17	7	568	6	566	5e-48	190
rs:WP_033698011	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	5e-48	189
rs:WP_002842888	DNA topoisomerase III [Campylobacter coli].	26.54	584	376	16	8	559	5	567	5e-48	189
rs:WP_004313263	DNA topoisomerase I [Bacteroides xylanisolvens].	29.09	574	345	20	4	552	1	537	5e-48	189
rs:WP_034820565	DNA topoisomerase [[Eubacterium] nodatum].	29.23	544	312	18	7	531	4	493	5e-48	187
rs:WP_012544366	DNA topoisomerase III [Coprothermobacter proteolyticus].	28.68	551	349	15	7	550	5	518	5e-48	189
rs:WP_044289457	MULTISPECIES: DNA topoisomerase III [Robinsoniella].	28.60	598	365	21	8	554	7	593	5e-48	189
rs:WP_039259014	DNA topoisomerase III [Clostridium botulinum].	28.27	566	351	22	8	532	7	558	5e-48	189
rs:WP_014262670	MULTISPECIES: DNA topoisomerase III [Firmicutes].	27.23	617	366	23	7	601	4	559	5e-48	187
rs:WP_042964849	DNA topoisomerase III [Campylobacter coli].	26.54	584	376	16	8	559	5	567	5e-48	189
rs:WP_033795073	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	5e-48	189
rs:WP_033581948	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	5e-48	189
rs:WP_032559152	DNA topoisomerase I [Bacteroides fragilis].	29.09	574	345	20	4	552	1	537	5e-48	189
rs:WP_026885431	DNA topoisomerase [Clostridium beijerinckii].	27.67	600	383	19	7	579	5	580	5e-48	189
tr:A0A0A5KV71_BURCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.34	561	367	15	7	550	6	548	5e-48	190
rs:WP_025477545	DNA topoisomerase [Enterococcus faecium].	29.50	583	369	17	5	563	3	567	5e-48	189
rs:WP_022118737	DNA topoisomerase [Firmicutes bacterium CAG:56].	28.60	556	342	16	7	532	5	535	5e-48	189
rs:WP_011546488	DNA topoisomerase III [Burkholderia cenocepacia].	28.34	561	367	15	7	550	6	548	5e-48	190
rs:WP_044930428	DNA topoisomerase III [Clostridium sp. M62/1].	26.74	561	355	16	7	549	4	526	5e-48	189
rs:WP_027281816	DNA topoisomerase III [Roseomonas gilardii].	26.99	552	349	13	7	531	6	530	5e-48	189
rs:WP_008565033	DNA topoisomerase III [Prevotella maculosa].	28.75	574	329	20	7	531	2	544	5e-48	189
rs:WP_007253354	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	26.44	609	395	16	4	574	1	594	5e-48	189
rs:WP_002306019	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	5e-48	189
rs:WP_034527038	DNA topoisomerase III [Bacteroides sp. 3_1_19].	27.83	539	342	17	8	531	5	511	5e-48	189
rs:WP_033583050	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	5e-48	189
rs:WP_007845609	DNA topoisomerase I [Bacteroides dorei].	28.08	616	377	22	4	591	1	578	5e-48	189
rs:WP_036610710	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	27.83	539	342	17	8	531	5	511	5e-48	189
rs:WP_012329439	DNA topoisomerase III [Burkholderia cenocepacia].	28.34	561	367	15	7	550	6	548	5e-48	190
tr:A2VUF6_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.34	561	367	15	7	550	29	571	5e-48	190
tr:D4QPS7_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.50	583	369	17	5	563	4	568	5e-48	189
rs:WP_024990268	DNA topoisomerase III [Prevotella albensis].	29.21	558	327	19	7	531	2	524	5e-48	189
rs:WP_041090884	DNA topoisomerase III [Jeotgalibacillus soli Cunha et al. 2012].	28.90	564	351	17	5	544	3	540	6e-48	189
rs:WP_007207501	DNA topoisomerase III [Enterococcus italicus].	28.14	565	323	21	7	550	5	507	6e-48	189
rs:WP_015480086	DNA topoisomerase III [Polaribacter sp. MED152].	27.88	538	341	16	8	531	5	509	6e-48	189
rs:WP_033606477	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	6e-48	189
rs:WP_033584975	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	6e-48	188
rs:WP_000779859	MULTISPECIES: DNA topoisomerase III [Streptococcus].	27.38	621	374	20	7	606	4	568	6e-48	187
rs:WP_027785766	DNA topoisomerase III [Burkholderia cepacia].	28.34	561	367	15	7	550	6	548	6e-48	189
rs:WP_015639657	DNA topoisomerase III [Lactobacillus plantarum].	29.16	583	369	19	5	563	3	565	6e-48	189
rs:WP_006299012	DNA topoisomerase III [Hylemonella gracilis].	27.93	605	371	21	5	568	3	583	6e-48	191
rs:WP_008513449	DNA topoisomerase III [Mucilaginibacter paludis].	28.22	567	349	16	4	543	1	536	6e-48	187
rs:WP_045243737	DNA topoisomerase III [Campylobacter coli].	26.54	584	376	16	8	559	5	567	6e-48	189
rs:WP_000779855	DNA topoisomerase [Streptococcus pneumoniae].	29.29	553	316	19	7	539	4	501	6e-48	187
tr:B5JFY2_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.78	556	357	16	7	539	5	544	6e-48	189
rs:WP_045409866	DNA topoisomerase III [Vibrio jasicida].	28.88	561	346	19	4	532	1	540	6e-48	189
rs:WP_033641561	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	6e-48	188
rs:WP_002857817	DNA topoisomerase III [Campylobacter jejuni].	26.54	584	376	16	8	559	5	567	6e-48	189
rs:WP_022525413	hypothetical protein [Streptococcus anginosus].	28.08	552	324	17	7	539	4	501	6e-48	187
rs:WP_005638126	conjugal transfer protein TraE [Haemophilus haemolyticus].	28.11	555	354	14	7	531	4	543	6e-48	189
rs:WP_033795582	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	6e-48	188
rs:WP_035114448	DNA topoisomerase [Clostridium sp. NCR].	28.64	597	383	19	7	590	4	570	6e-48	189
tr:F6IW93_LACPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.99	583	370	19	5	563	3	565	6e-48	189
rs:WP_033607310	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	6e-48	188
rs:WP_008352195	MULTISPECIES: DNA topoisomerase III [Burkholderia].	28.18	582	377	17	7	568	6	566	6e-48	189
rs:WP_021432150	DNA topoisomerase [[Clostridium] bifermentans].	28.64	597	383	19	7	590	4	570	6e-48	189
rs:WP_001681355	DNA topoisomerase III, partial [Salmonella enterica].	28.45	457	305	12	7	452	4	449	7e-48	184
rs:WP_033629071	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	7e-48	188
rs:WP_033655380	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	7e-48	188
rs:WP_016998796	hypothetical protein [Staphylococcus lentus].	26.15	566	375	15	7	559	5	540	7e-48	188
rs:WP_006783219	DNA topoisomerase [Turicibacter sanguinis].	30.08	502	320	10	48	534	37	522	7e-48	189
rs:WP_044649609	DNA topoisomerase III, partial [Klebsiella variicola].	28.78	476	308	11	97	552	21	485	7e-48	187
rs:WP_004819943	DNA topoisomerase III [Peptoniphilus indolicus].	28.41	542	335	17	7	539	4	501	7e-48	187
rs:WP_044074329	DNA topoisomerase III [Prevotella sp. P5-60].	28.18	550	336	17	7	531	2	517	7e-48	188
rs:WP_013385940	DNA topoisomerase III [Paenibacillus polymyxa].	26.68	551	364	14	14	546	2	530	7e-48	189
rs:WP_040900160	DNA topoisomerase III, partial [Verrucomicrobiae bacterium DG1235].	28.78	556	357	16	7	539	6	545	7e-48	189
rs:WP_022367814	DNA topoisomerase III [Firmicutes bacterium CAG:882].	26.90	617	362	20	8	554	7	604	7e-48	188
rs:WP_003045929	hypothetical protein [Streptococcus canis].	27.99	561	348	16	4	550	2	520	7e-48	187
rs:WP_023414868	hypothetical protein [uncultured Thiohalocapsa sp. PB-PSB1].	27.75	645	389	20	5	606	3	613	7e-48	190
rs:WP_011187227	cpp49 [Campylobacter coli].	26.37	584	377	16	8	559	5	567	7e-48	189
rs:WP_034280392	conjugal transfer protein TraE, partial [Alkanindiges illinoisensis].	27.15	571	368	16	7	548	7	558	7e-48	188
rs:WP_036740468	DNA topoisomerase III, partial [Peptostreptococcaceae bacterium oral taxon 113].	27.87	610	367	19	7	590	4	566	7e-48	188
rs:WP_009606218	DNA topoisomerase [Turicibacter sp. HGF1].	30.08	502	320	10	48	534	37	522	7e-48	189
rs:WP_028259688	DNA topoisomerase III [Variovorax sp. JGI 0001016-M12].	28.76	612	364	25	5	568	4	591	7e-48	190
rs:WP_027321998	DNA topoisomerase III [Bacillus sp. URHB0009].	27.86	542	353	14	7	530	4	525	8e-48	188
rs:WP_013871149	DNA topoisomerase III [Lacinutrix sp. 5H-3-7-4].	28.18	550	356	17	8	550	5	522	8e-48	189
rs:WP_011633516	DNA topoisomerase III [Nitrosomonas eutropha].	28.60	570	357	17	7	550	6	551	8e-48	189
rs:WP_039597233	DNA topoisomerase III [Ralstonia sp. A12].	28.55	599	370	20	7	577	6	574	8e-48	189
rs:WP_022203700	DNA topoisomerase [Eubacterium sp. CAG:248].	27.99	593	353	21	8	539	7	586	8e-48	188
rs:WP_011861365	DNA topoisomerase [Peptoclostridium difficile].	27.86	542	338	17	7	539	4	501	8e-48	187
rs:WP_022101784	DNA topoisomerase III [Prevotella sp. CAG:5226].	28.47	569	343	18	7	531	2	550	8e-48	188
rs:WP_024668910	DNA topoisomerase III, partial [Pseudomonas syringae].	27.60	587	381	15	8	565	5	576	8e-48	187
rs:WP_021429852	DNA topoisomerase [[Clostridium] bifermentans].	28.64	597	383	19	7	590	4	570	8e-48	188
tr:U2JQH5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.87	610	367	19	7	590	4	566	8e-48	188
rs:WP_018903490	DNA topoisomerase III [Variovorax paradoxus].	28.76	612	364	25	5	568	3	590	8e-48	190
rs:WP_027449112	DNA topoisomerase III [Prevotella brevis].	29.23	561	320	22	7	531	2	521	8e-48	188
rs:WP_025161624	DNA topoisomerase [[Clostridium] bifermentans].	28.64	597	383	19	7	590	4	570	8e-48	188
rs:WP_012779890	DNA topoisomerase III [Dyadobacter fermentans].	29.76	541	328	18	8	531	5	510	8e-48	188
rs:WP_031645736	DNA topoisomerase [Listeria monocytogenes].	28.96	556	364	16	5	544	3	543	8e-48	188
rs:WP_021562493	hypothetical protein [Escherichia coli].	28.92	567	358	15	7	543	4	555	8e-48	189
rs:WP_046465821	DNA topoisomerase III [Staphylococcus equorum].	26.74	576	359	17	7	559	5	540	8e-48	188
rs:WP_015856075	DNA topoisomerase III [Ralstonia pickettii].	29.17	600	365	21	7	577	6	574	9e-48	189
rs:WP_007790408	DNA topoisomerase III [Peptostreptococcus stomatis].	29.60	554	311	20	8	539	5	501	9e-48	186
rs:WP_045706786	DNA topoisomerase III [Desulfobulbaceae bacterium BRH_c16a].	30.30	594	364	22	1	567	1	571	9e-48	189
rs:WP_018704325	MULTISPECIES: hypothetical protein [Veillonellaceae].	28.26	605	378	17	7	582	5	582	9e-48	188
rs:WP_045575207	DNA topoisomerase III [Desulfosporosinus sp. I2].	26.85	648	404	20	7	606	6	631	9e-48	188
rs:WP_002839589	DNA topoisomerase III, partial [Campylobacter coli].	26.20	584	378	16	8	559	5	567	9e-48	187
rs:WP_007709571	hypothetical protein [[Clostridium] asparagiforme].	27.50	560	351	18	7	550	4	524	9e-48	188
rs:WP_016220727	DNA topoisomerase III [Dorea sp. 5-2].	28.22	567	340	18	7	549	4	527	9e-48	188
rs:WP_016276696	DNA topoisomerase III [Bacteroides massiliensis].	28.92	574	346	20	4	552	1	537	9e-48	188
rs:WP_039352756	DNA topoisomerase III [Chryseobacterium jeonii].	29.76	541	331	18	8	531	5	513	9e-48	188
rs:WP_002596245	DNA topoisomerase III [[Clostridium] clostridioforme].	27.86	560	348	15	7	549	4	524	9e-48	188
rs:WP_004570515	DNA topoisomerase III [Polaribacter irgensii].	26.82	537	348	15	8	531	5	509	1e-47	188
rs:WP_002577979	DNA topoisomerase III [[Clostridium] bolteae].	26.69	562	351	16	7	548	6	526	1e-47	188
rs:WP_044931597	hypothetical protein, partial [Butyrivibrio sp. AC2005].	28.87	582	366	20	7	550	5	576	1e-47	188
rs:WP_029997262	DNA topoisomerase [Streptococcus suis].	28.57	567	337	17	4	550	2	520	1e-47	187
rs:WP_005614699	DNA topoisomerase III [Pseudomonas avellanae].	26.40	591	391	15	4	565	1	576	1e-47	188
rs:WP_009316961	DNA topoisomerase III [Tannerella sp. 6_1_58FAA_CT1].	28.94	539	337	18	8	531	5	512	1e-47	188
rs:WP_022168305	DNA topoisomerase [Clostridium sp. CAG:221].	27.45	612	392	21	7	590	5	592	1e-47	188
rs:WP_022629531	DNA topoisomerase III [Bacillus marmarensis].	29.03	558	352	19	5	548	4	531	1e-47	188
rs:WP_033407435	DNA topoisomerase III, partial [Uliginosibacterium gangwonense].	28.34	607	384	21	7	592	6	582	1e-47	189
rs:WP_041512402	DNA topoisomerase III [Nitrosospira sp. NpAV].	29.40	551	345	17	5	531	4	534	1e-47	189
rs:WP_004329672	DNA topoisomerase I [Alistipes putredinis].	29.09	574	345	20	4	552	1	537	1e-47	188
rs:WP_021375895	DNA topoisomerase [Peptoclostridium difficile].	29.03	596	384	17	7	590	4	572	1e-47	188
rs:WP_035119416	DNA topoisomerase III [Cohnella panacarvi].	26.18	634	396	17	5	599	3	603	1e-47	188
rs:WP_022400369	DNA topoisomerase [Roseburia sp. CAG:471].	28.36	550	346	16	5	532	3	526	1e-47	188
rs:WP_033692241	hypothetical protein, partial [Bacillus sp. GeD10].	26.58	523	336	13	4	499	1	502	1e-47	185
rs:WP_036730954	DNA topoisomerase III [Paenibacillus sp. FSL R7-277].	28.16	561	337	16	7	544	5	522	1e-47	188
rs:WP_008427758	topoisomerase IA [Clostridium sp. Maddingley MBC34-26].	27.67	600	383	18	7	579	5	580	1e-47	188
rs:WP_013773769	DNA topoisomerase III [Melissococcus plutonius].	28.03	553	339	18	7	550	7	509	1e-47	187
rs:WP_021196961	DNA topoisomerase III [Ralstonia sp. AU12-08].	28.19	596	376	19	7	577	6	574	1e-47	189
rs:WP_044397968	DNA topoisomerase III [Lacinutrix sp. Hel_I_90].	27.95	551	357	17	8	550	5	523	1e-47	188
rs:WP_042722218	DNA topoisomerase III, partial [Flavobacterium sp. B17].	29.60	544	329	20	8	531	5	514	1e-47	187
rs:WP_007566776	DNA topoisomerase III [Bacteroides coprocola].	28.39	539	342	17	7	531	2	510	1e-47	188
rs:WP_036204228	hypothetical protein, partial [Lysinibacillus sinduriensis].	28.54	522	328	16	47	549	35	530	1e-47	187
rs:WP_020082018	DNA topoisomerase III [Flavobacterium sp. SCGC AAA160-P02].	27.32	538	344	16	8	531	5	509	1e-47	188
rs:WP_040142560	DNA topoisomerase III [Burkholderia cenocepacia].	28.16	561	368	15	7	550	6	548	1e-47	189
rs:WP_042735322	DNA topoisomerase III [Lachnospiraceae bacterium TWA4].	28.83	614	356	23	8	568	6	591	1e-47	187
rs:WP_042258672	DNA topoisomerase III, partial [Butyrivibrio proteoclasticus].	28.60	591	361	22	8	554	7	580	1e-47	187
rs:WP_039660485	DNA topoisomerase III, partial [Pantoea sp. MBLJ3].	30.08	399	252	11	170	552	63	450	1e-47	186
rs:WP_029140971	DNA topoisomerase III [Streptococcus agalactiae].	28.55	543	333	17	7	539	4	501	1e-47	186
rs:WP_039069501	DNA topoisomerase III [Staphylococcus xylosus].	25.28	621	407	20	7	606	5	589	1e-47	187
rs:WP_032517408	DNA topoisomerase III, partial [Peptoclostridium difficile].	30.57	507	285	16	7	491	4	465	1e-47	184
rs:WP_022600591	DNA topoisomerase III [Coprobacter fastidiosus].	28.94	539	337	18	8	531	5	512	1e-47	187
rs:WP_009262078	DNA topoisomerase III [Coprococcus sp. HPP0074].	27.70	574	360	19	5	534	4	566	1e-47	187
rs:WP_045325285	DNA topoisomerase III [Enterobacter cloacae].	29.00	569	355	15	7	543	4	555	1e-47	188
rs:WP_022376747	DNA topoisomerase III [Clostridium sp. CAG:62].	27.90	613	357	23	7	554	6	598	1e-47	187
rs:WP_009239400	MULTISPECIES: DNA topoisomerase III [Ralstonia].	28.83	600	367	21	7	577	6	574	1e-47	189
rs:WP_042890171	DNA topoisomerase III [Enterococcus faecalis].	29.17	576	331	23	7	563	5	522	1e-47	187
rs:WP_003431259	DNA topoisomerase [Peptoclostridium difficile].	28.04	560	348	19	7	550	4	524	1e-47	187
rs:WP_044514344	DNA topoisomerase III [Hymenobacter sp. DG25B].	27.30	586	361	19	4	550	1	560	1e-47	188
rs:WP_041114323	DNA topoisomerase III [Bacillus badius].	29.45	567	351	18	5	548	3	543	1e-47	187
rs:WP_031399650	MULTISPECIES: DNA topoisomerase III [Burkholderia].	26.77	620	412	17	7	603	6	606	1e-47	189
rs:WP_025789617	DNA topoisomerase III [Vibrio parahaemolyticus].	28.29	562	376	12	7	549	4	557	1e-47	187
rs:WP_022182875	DNA topoisomerase [Clostridium sp. CAG:575].	26.40	591	362	15	7	532	6	588	1e-47	187
rs:WP_032585698	DNA topoisomerase I [Bacteroides fragilis].	29.09	574	345	20	4	552	1	537	1e-47	187
tr:C9AL42_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.75	574	336	24	7	563	5	522	1e-47	187
rs:WP_034857843	DNA topoisomerase III [Enterococcus casseliflavus].	28.75	574	336	21	7	563	5	522	1e-47	187
rs:WP_034211840	DNA topoisomerase [Lachnoanaerobaculum sp. MSX33].	29.96	544	324	19	7	539	4	501	1e-47	186
rs:WP_031833160	DNA topoisomerase III, partial [Staphylococcus aureus].	30.09	545	348	16	12	544	1	524	1e-47	187
rs:WP_021542872	hypothetical protein [Escherichia coli].	29.00	569	355	15	7	543	4	555	1e-47	188
rs:WP_031863365	DNA topoisomerase III, partial [Staphylococcus aureus].	27.94	519	330	16	56	559	6	495	1e-47	187
rs:WP_029285251	DNA topoisomerase I [Pedobacter sp. R20-19].	28.09	566	345	17	7	543	4	536	1e-47	187
rs:WP_010027006	DNA topoisomerase III [Sporolactobacillus inulinus].	28.19	564	335	18	7	548	6	521	1e-47	187
rs:WP_044976020	DNA topoisomerase III, partial [[Eubacterium] cellulosolvens].	28.50	572	339	17	7	547	4	536	1e-47	186
tr:Q2BXW9_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.73	436	279	10	114	531	9	439	1e-47	186
rs:WP_021908894	DNA topoisomerase III bacteria and conjugative plasmid [Prevotella sp. CAG:755].	27.06	606	390	15	4	592	1	571	1e-47	187
tr:V2Y4D4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.71	613	365	19	5	558	4	603	2e-47	187
rs:WP_019967377	DNA topoisomerase III [Prevotella maculosa].	28.75	574	329	20	7	531	2	544	2e-47	187
rs:WP_016441614	DNA topoisomerase III [Coprococcus sp. HPP0048].	27.71	563	347	16	7	539	5	537	2e-47	187
rs:WP_016169468	DNA topoisomerase III [Lachnospiraceae bacterium 10-1].	27.16	578	359	19	8	534	7	573	2e-47	187
rs:WP_017646907	DNA topoisomerase [Streptococcus agalactiae].	28.50	621	371	22	4	602	2	571	2e-47	186
rs:WP_010700012	DNA topoisomerase [Acinetobacter radioresistens].	29.29	618	356	21	7	561	4	603	2e-47	189
rs:WP_033624436	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	2e-47	187
rs:WP_002375953	DNA topoisomerase [Enterococcus faecium].	29.33	583	370	17	5	563	3	567	2e-47	187
rs:WP_035664890	DNA topoisomerase III [Bacillus akibai].	28.24	602	389	18	4	583	1	581	2e-47	187
rs:WP_002387619	DNA topoisomerase [Enterococcus faecalis].	28.96	556	364	16	5	544	3	543	2e-47	187
rs:WP_002662996	DNA topoisomerase III [Bergeyella zoohelcum].	28.60	542	336	18	8	531	5	513	2e-47	187
rs:WP_002317775	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	2e-47	187
rs:WP_009274928	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	27.64	539	343	17	8	531	5	511	2e-47	187
rs:WP_032600155	DNA topoisomerase III, partial [Campylobacter jejuni].	26.71	584	375	16	8	559	5	567	2e-47	187
rs:WP_016278733	DNA topoisomerase III [Lachnospiraceae bacterium A4].	28.17	607	362	17	7	550	6	601	2e-47	190
rs:WP_013521814	DNA topoisomerase III [Taylorella equigenitalis].	29.02	572	356	18	3	543	2	554	2e-47	188
rs:WP_035334438	MULTISPECIES: DNA topoisomerase III, partial [Bacillus].	30.45	532	325	20	7	531	5	498	2e-47	187
rs:WP_022126066	DNA topoisomerase III [Bacteroides coprocola CAG:162].	28.39	539	342	17	7	531	2	510	2e-47	187
tr:I5AS62_EUBCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.32	572	340	16	7	547	4	536	2e-47	186
rs:WP_006287544	topoisomerase IA [Paenibacillus popilliae].	27.11	568	343	16	7	550	5	525	2e-47	187
rs:WP_016412253	DNA topoisomerase III [Prevotella sp. CAG:1031].	27.59	551	355	15	8	543	5	526	2e-47	186
rs:WP_035040382	hypothetical protein, partial [Catonella morbi].	28.71	613	365	19	5	558	4	603	2e-47	187
rs:WP_046180764	hypothetical protein [Domibacillus sp. PAMC 80007].	26.65	544	368	13	4	532	1	528	2e-47	187
rs:WP_041335059	DNA topoisomerase III [Bacillus subtilis].	29.17	576	352	21	7	563	5	543	2e-47	187
rs:WP_008772022	DNA topoisomerase I [Bacteroides sp. 2_1_33B].	28.92	574	346	20	4	552	1	537	2e-47	187
rs:WP_024417943	DNA topoisomerase [Streptococcus suis].	28.57	567	337	17	4	550	2	520	2e-47	186
gp:CP002030_34	cpp49 [Campylobacter jejuni subsp. jejuni ICDCCJ07001]	26.71	584	375	16	8	559	5	567	2e-47	187
rs:WP_004070731	DNA topoisomerase III [Clostridium sp. ASF502].	28.52	568	337	17	7	549	4	527	2e-47	187
rs:WP_034179361	DNA topoisomerase III [Burkholderia pyrrocinia].	28.34	561	367	15	7	550	6	548	2e-47	188
rs:WP_022391175	DNA topoisomerase III [Tannerella sp. CAG:51].	28.94	539	337	18	8	531	5	512	2e-47	187
tr:D6DKQ5_CLOSC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.39	560	346	19	7	550	4	524	2e-47	187
rs:WP_035066874	hypothetical protein, partial [Carnobacterium maltaromaticum].	28.18	550	326	21	5	531	4	507	2e-47	187
rs:WP_029949204	DNA topoisomerase [Parvimonas micra].	28.86	544	314	17	7	531	4	493	2e-47	186
rs:WP_026195590	topoisomerase I [Verrucomicrobium sp. 3C].	28.93	553	348	16	5	531	4	537	2e-47	188
rs:WP_036633291	hypothetical protein, partial [Paenibacillus alginolyticus].	28.57	511	328	14	43	531	42	537	2e-47	187
rs:WP_025194984	DNA topoisomerase III [Streptococcus agalactiae].	28.57	553	320	19	7	539	6	503	2e-47	186
rs:WP_011282367	TraE-like protein [Haemophilus influenzae].	27.22	551	364	11	7	531	4	543	2e-47	187
tr:F0GKV0_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.34	561	367	15	7	550	6	548	2e-47	187
tr:G5GB63_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.32	565	344	19	4	531	36	576	2e-47	187
rs:WP_002308233	DNA topoisomerase III [Enterococcus faecium].	27.97	572	343	22	7	563	5	522	2e-47	187
rs:WP_025983421	DNA topoisomerase III [Vibrio parahaemolyticus].	29.08	564	341	18	4	532	1	540	2e-47	187
rs:WP_046544168	DNA topoisomerase III [Burkholderia contaminans].	26.77	620	412	17	7	603	6	606	2e-47	188
rs:WP_022334396	DNA topoisomerase [Clostridium sp. CAG:452].	27.04	577	356	18	7	532	5	567	2e-47	186
rs:WP_045205150	DNA topoisomerase III [Burkholderiaceae bacterium 26].	28.38	599	371	20	7	577	6	574	2e-47	188
rs:WP_041941796	DNA topoisomerase, partial [Waddlia chondrophila].	28.92	574	359	21	4	563	1	539	2e-47	186
rs:WP_045362785	DNA topoisomerase III [Enterobacter aerogenes].	29.00	569	355	15	7	543	4	555	2e-47	187
rs:WP_006774454	DNA topoisomerase III [[Clostridium] hathewayi].	28.39	560	346	19	7	550	4	524	2e-47	187
rs:WP_004381429	DNA topoisomerase III [Prevotella oulorum].	28.68	551	337	17	7	531	2	522	2e-47	187
rs:WP_010815313	DNA topoisomerase III [Enterococcus faecalis].	27.89	563	343	15	7	539	4	533	2e-47	187
rs:WP_018914713	DNA topoisomerase III [Thiomonas sp. FB-6].	28.47	590	375	20	3	567	2	569	2e-47	188
rs:WP_017650630	DNA topoisomerase [Streptococcus agalactiae].	28.50	621	371	22	4	602	2	571	2e-47	186
rs:WP_039930399	DNA topoisomerase III, partial [Anaerostipes sp. 3_2_56FAA].	28.06	506	325	12	7	498	6	486	2e-47	184
rs:WP_002313368	DNA topoisomerase III [Enterococcus faecium].	27.97	572	343	22	7	563	5	522	2e-47	187
rs:WP_038611241	DNA topoisomerase I [Bacteroides dorei].	28.92	574	346	20	4	552	1	537	2e-47	187
rs:WP_016316312	DNA topoisomerase III [Anaerotruncus sp. G3(2012)].	28.10	605	371	20	7	590	5	566	2e-47	187
rs:WP_046822078	DNA topoisomerase [Clostridium sp. JC272].	28.64	597	383	19	7	590	4	570	2e-47	187
rs:WP_029192188	DNA topoisomerase III [Paenibacillus harenae].	27.44	583	320	19	7	544	5	529	2e-47	187
tr:F8LD86_9CHLA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.92	574	359	21	4	563	1	539	2e-47	186
rs:WP_019451929	DNA topoisomerase III [Cupriavidus sp. BIS7].	28.16	593	383	17	7	577	6	577	2e-47	188
rs:WP_002511446	DNA topoisomerase III [Staphylococcus equorum].	26.29	582	354	17	7	559	5	540	2e-47	187
rs:WP_004294818	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	27.70	621	373	22	4	591	1	578	2e-47	187
gpu:CP011503_1109	DNA topoisomerase III [Burkholderia pyrrocinia]	28.16	561	368	15	7	550	6	548	2e-47	188
rs:WP_041877376	DNA topoisomerase I [Pedobacter sp. NL19].	29.53	552	331	19	7	531	4	524	2e-47	186
rs:WP_033612353	DNA topoisomerase III [Enterococcus faecium].	29.09	574	334	24	7	563	5	522	2e-47	187
rs:WP_021956985	DNA topoisomerase [Eubacterium sp. CAG:115].	31.03	551	317	21	7	537	4	511	2e-47	187
rs:WP_002484856	DNA topoisomerase III [Staphylococcus epidermidis].	27.38	526	337	11	7	519	5	498	2e-47	184
rs:WP_019429929	DNA topoisomerase III [Limnohabitans sp. Rim47].	27.89	606	370	23	5	568	3	583	2e-47	189
rs:WP_039042607	DNA topoisomerase III [Sporosarcina sp. ZBG7A].	28.18	550	368	15	7	544	5	539	2e-47	187
rs:WP_033652941	DNA topoisomerase III [Enterococcus faecium].	28.97	573	336	23	7	563	5	522	2e-47	187
rs:WP_016147259	DNA topoisomerase III [Butyricicoccus pullicaecorum].	26.81	567	353	16	7	549	4	532	2e-47	187
rs:WP_042061035	DNA topoisomerase III [Escherichia coli].	28.30	569	359	15	7	543	4	555	2e-47	187
rs:WP_021393615	DNA topoisomerase III family protein [Peptoclostridium difficile].	26.88	558	357	16	7	550	4	524	2e-47	187
rs:WP_000259054	DNA topoisomerase III [Streptococcus agalactiae].	27.21	621	379	21	4	602	2	571	2e-47	185
rs:WP_015059067	DNA topoisomerase III [Escherichia coli].	28.82	569	356	15	7	543	4	555	2e-47	187
rs:WP_010749200	DNA topoisomerase III, partial [Enterococcus casseliflavus].	28.60	556	366	15	5	544	3	543	3e-47	185
rs:WP_040053214	DNA topoisomerase III [Burkholderia sp. MR1].	27.81	579	383	17	7	568	6	566	3e-47	188
rs:WP_032702136	DNA topoisomerase III, partial [Campylobacter coli].	26.63	582	378	16	8	559	5	567	3e-47	186
rs:WP_020162915	DNA topoisomerase III [Methyloversatilis universalis].	29.01	555	344	20	7	531	6	540	3e-47	188
rs:WP_032558364	DNA topoisomerase I [Bacteroides fragilis].	27.70	621	373	22	4	591	1	578	3e-47	187
rs:WP_034446774	DNA topoisomerase [Butyrivibrio sp. AE2032].	27.97	597	368	19	7	553	6	590	3e-47	189
tr:E6PWK5_9ZZZZ	SubName: Full=Putative DNA topoisomerase III, bacterial-type {ECO:0000313|EMBL:CBH99312.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBH99312.1};	29.17	593	373	20	3	568	2	574	3e-47	188
rs:WP_033627655	DNA topoisomerase III [Enterococcus faecium].	28.92	574	335	24	7	563	5	522	3e-47	186
rs:WP_045689151	DNA topoisomerase III [Hymenobacter sp. AT01-02].	27.60	576	352	21	4	539	1	551	3e-47	187
rs:WP_044677942	DNA topoisomerase [Streptococcus suis].	28.40	567	338	17	4	550	2	520	3e-47	185
rs:WP_027955625	DNA topoisomerase III [Halobacillus kuroshimensis].	29.08	564	346	17	7	544	6	541	3e-47	187
rs:WP_022502109	DNA topoisomerase III [Eubacterium sp. CAG:76].	27.21	599	372	21	8	554	7	593	3e-47	186
rs:WP_017643397	DNA topoisomerase III [Streptococcus agalactiae].	27.20	625	374	21	4	602	2	571	3e-47	185
rs:WP_025065874	DNA topoisomerase III [Prevotella enoeca].	27.94	544	342	17	7	531	2	514	3e-47	186
tr:E5VST4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	28.06	506	325	12	7	498	6	486	3e-47	184
rs:WP_006798321	DNA topoisomerase I [Dysgonomonas gadei].	28.17	575	358	17	7	558	4	546	3e-47	186
rs:WP_021909342	DNA topoisomerase III [Prevotella sp. CAG:755].	28.47	555	351	17	7	543	2	528	3e-47	186
rs:WP_039318048	DNA topoisomerase III [Burkholderia sp. A9].	27.99	561	369	15	7	550	6	548	3e-47	187
rs:WP_043933664	DNA topoisomerase [Bacillus sp. EB01].	27.98	604	380	17	7	582	5	581	3e-47	187
rs:WP_034567039	DNA topoisomerase III [Clostridiales bacterium VE202-03].	26.77	564	351	15	7	549	4	526	3e-47	186
rs:WP_038206454	DNA topoisomerase III [Xenophilus azovorans].	29.06	616	359	26	5	568	4	593	3e-47	189
tr:A0A078BQA6_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.69	596	372	21	3	568	2	574	3e-47	187
rs:WP_034217873	DNA topoisomerase III [Lachnospiraceae bacterium AB2028].	28.03	610	348	22	1	532	1	597	3e-47	187
rs:WP_042108034	DNA topoisomerase III, partial [Escherichia coli].	28.51	456	304	12	8	452	5	449	3e-47	182
rs:WP_006037718	DNA topoisomerase III [Paenibacillus curdlanolyticus].	27.71	646	365	25	7	604	5	596	3e-47	187
tr:D4LTS8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.65	555	333	18	7	539	4	517	3e-47	186
rs:WP_006059585	DNA topoisomerase III [Holdemania filiformis].	26.77	564	351	15	7	549	4	526	3e-47	186
rs:WP_013122335	DNA topoisomerase III [Thiomonas intermedia].	28.69	596	372	21	3	568	2	574	3e-47	187
tr:E0S4A4_BUTPB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.60	591	361	22	8	554	7	580	3e-47	187
rs:WP_024389804	DNA topoisomerase [Streptococcus suis].	28.57	567	337	17	4	550	2	520	3e-47	185
rs:WP_009289563	MULTISPECIES: DNA topoisomerase III [Anaerostipes].	26.66	589	378	20	8	554	6	582	3e-47	186
rs:WP_034201218	DNA topoisomerase III [Burkholderia cepacia].	28.16	561	368	15	7	550	6	548	3e-47	187
rs:WP_010232935	DNA topoisomerase [Clostridium arbusti].	28.10	548	351	16	7	532	5	531	3e-47	186
rs:WP_034215261	DNA topoisomerase [Lachnoanaerobaculum sp. MSX33].	29.27	550	324	19	7	539	4	505	3e-47	185
rs:WP_003508269	DNA topoisomerase [[Clostridium] symbiosum].	28.75	560	344	20	7	550	4	524	3e-47	186
rs:WP_045850186	hypothetical protein [Domibacillus enclensis].	27.21	544	365	14	4	532	1	528	3e-47	186
rs:WP_044847346	DNA topoisomerase III [Burkholderia sp. USM B20].	28.16	561	368	15	7	550	6	548	3e-47	187
rs:WP_040041719	DNA topoisomerase III [Herbaspirillum sp. TSA66].	28.11	594	377	19	5	571	4	574	3e-47	187
rs:WP_033649945	DNA topoisomerase, partial [Enterococcus sp. GMD1E].	29.02	510	330	14	5	498	3	496	3e-47	184
rs:WP_023043299	DNA topoisomerase III, partial [Enterococcus faecium].	29.55	511	322	17	5	495	3	495	3e-47	184
rs:WP_022149832	DNA topoisomerase III [Prevotella sp. CAG:1320].	28.49	558	330	19	7	531	2	523	3e-47	186
rs:WP_009524905	DNA topoisomerase III [Peptostreptococcaceae bacterium ACC19a].	27.45	612	385	20	7	606	6	570	3e-47	185
rs:WP_032569621	DNA topoisomerase I [Bacteroides fragilis].	27.70	621	373	22	4	591	1	578	3e-47	186
rs:WP_031444327	DNA topoisomerase III [Arenibacter algicola].	27.87	531	347	15	8	531	5	506	3e-47	187
tr:E1JMD1_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.18	562	321	22	7	550	5	507	3e-47	184
rs:WP_009568422	DNA topoisomerase III family protein [Streptococcus intermedius].	28.80	552	320	18	7	539	4	501	3e-47	185
rs:WP_025020293	DNA topoisomerase III [Lactobacillus equi].	28.83	562	323	20	7	550	6	508	3e-47	186
rs:WP_027454557	DNA topoisomerase III [Prevotella brevis].	29.06	561	321	22	7	531	2	521	3e-47	186
rs:WP_002804385	DNA topoisomerase III, partial [Campylobacter coli].	26.37	584	377	16	8	559	5	567	3e-47	186
rs:WP_009682480	MULTISPECIES: DNA topoisomerase III [Pseudomonas].	26.50	566	364	17	8	530	7	563	3e-47	187
rs:WP_009322007	DNA topoisomerase III [Subdoligranulum sp. 4_3_54A2FAA].	26.76	568	358	15	1	549	1	529	3e-47	186
rs:WP_020897137	DNA topoisomerase III [Winogradskyella psychrotolerans].	28.19	557	355	17	8	550	5	530	3e-47	186
rs:WP_040128547	DNA topoisomerase III [Burkholderia cenocepacia].	28.34	561	367	15	7	550	6	548	4e-47	187
rs:WP_035518992	DNA topoisomerase, partial [Burkholderia sp. Ch1-1].	29.87	539	326	20	7	515	6	522	4e-47	184
rs:WP_036650398	DNA topoisomerase III [Paenibacillus wynnii].	27.34	567	324	17	7	539	5	517	4e-47	186
rs:WP_014003991	DNA topoisomerase [Pseudomonas putida].	26.50	566	364	17	8	530	8	564	4e-47	187
rs:WP_027678685	DNA topoisomerase III [Ralstonia sp. UNC404CL21Col].	29.00	600	366	21	7	577	6	574	4e-47	187
rs:WP_007653064	DNA topoisomerase I [Parabacteroides goldsteinii].	28.82	576	344	20	4	552	1	537	4e-47	186
rs:WP_023237100	DNA topoisomerase, partial [Salmonella enterica].	28.47	569	358	15	7	543	4	555	4e-47	186
rs:WP_037612753	DNA topoisomerase [Streptococcus sp. OBRC6].	27.90	552	325	18	7	539	4	501	4e-47	185
rs:WP_040597623	DNA topoisomerase III [Alloprevotella rava].	28.29	562	342	19	7	531	2	539	4e-47	186
rs:WP_002869583	DNA topoisomerase III [Campylobacter jejuni].	26.37	584	377	16	8	559	5	567	4e-47	186
rs:WP_025367771	DNA topoisomerase III [Klebsiella pneumoniae].	29.17	569	354	15	7	543	4	555	4e-47	186
rs:WP_009672956	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	28.60	542	318	16	29	545	28	525	4e-47	185
rs:WP_032592777	DNA topoisomerase III, partial [Campylobacter jejuni].	26.63	582	378	16	8	559	5	567	4e-47	186
rs:WP_004233245	DNA topoisomerase III [Lysinibacillus fusiformis].	29.23	568	351	17	7	548	6	548	4e-47	186
rs:WP_031527797	DNA topoisomerase III [Dyadobacter crusticola].	29.10	543	329	17	8	531	5	510	4e-47	186
rs:WP_024992172	DNA topoisomerase III [Prevotella pleuritidis].	27.94	544	342	17	7	531	2	514	4e-47	186
rs:WP_021583388	DNA topoisomerase III [Prevotella pleuritidis].	28.26	545	339	18	7	531	2	514	4e-47	186
rs:WP_032572212	DNA topoisomerase I [Bacteroides fragilis].	28.92	574	346	20	4	552	1	537	4e-47	186
rs:WP_040531935	DNA topoisomerase III, partial [Lautropia mirabilis].	28.65	569	356	19	7	550	6	549	4e-47	187
rs:WP_021853873	DNA topoisomerase III [Prevotella sp. CAG:255].	28.68	544	338	16	7	531	2	514	4e-47	186
tr:E2SL06_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.77	564	351	15	7	549	4	526	4e-47	186
rs:WP_025477548	DNA topoisomerase [Enterococcus faecium].	29.33	583	370	17	5	563	3	567	4e-47	186
rs:WP_036786249	DNA topoisomerase III [Polaribacter sp. Hel1_33_49].	27.32	538	344	16	8	531	5	509	4e-47	186
rs:WP_032581312	DNA topoisomerase I [Bacteroides fragilis].	29.09	574	345	20	4	552	1	537	4e-47	186
rs:WP_025082441	DNA topoisomerase III [Lactobacillus fuchuensis].	28.75	567	317	19	7	550	6	508	4e-47	186
rs:WP_002368714	MULTISPECIES: DNA topoisomerase III [Enterococcus].	27.62	554	341	15	7	539	4	518	4e-47	186
gpu:AP013045_655	DNA topoisomerase [Tannerella forsythia KS16]	27.54	541	344	16	8	531	5	514	4e-47	186
rs:WP_021159862	DNA topoisomerase III [Burkholderia sp. AU4i].	28.16	561	368	15	7	550	6	548	4e-47	187
rs:WP_004309983	DNA topoisomerase I [Bacteroides ovatus].	29.09	574	345	20	4	552	1	537	4e-47	186
rs:WP_033643474	DNA topoisomerase III [Enterococcus faecium].	27.97	572	343	22	7	563	5	522	4e-47	186
rs:WP_006763069	DNA topoisomerase III [Burkholderia dolosa].	28.52	561	366	15	7	550	6	548	4e-47	187
rs:WP_039353751	DNA topoisomerase III [Mumia flava].	26.77	620	412	17	7	603	6	606	4e-47	187
rs:WP_040281935	DNA topoisomerase III [Psychroserpens damuponensis].	28.54	536	339	16	8	531	5	508	4e-47	186
rs:WP_043461343	hypothetical protein, partial [Azohydromonas australica].	28.57	588	326	21	5	536	3	552	4e-47	186
rs:WP_021338404	DNA topoisomerase III [Staphylococcus equorum].	26.29	582	354	17	7	559	5	540	4e-47	186
rs:WP_008752394	DNA topoisomerase III [Lachnoanaerobaculum saburreum].	29.27	550	324	19	7	539	4	505	4e-47	184
rs:WP_019427399	DNA topoisomerase III [Limnohabitans sp. Rim28].	28.34	607	366	25	5	568	3	583	4e-47	188
rs:WP_010100721	DNA topoisomerase III [Burkholderia oklahomensis].	27.99	561	369	15	7	550	6	548	4e-47	187
rs:WP_013648723	DNA topoisomerase III [Nitrosomonas sp. AL212].	29.03	565	361	16	7	550	6	551	4e-47	187
rs:WP_025015836	DNA topoisomerase III [Lactobacillus sakei].	28.70	561	326	20	7	550	6	509	4e-47	186
rs:WP_019413664	hypothetical protein [Paenisporosarcina sp. TG20].	28.83	562	356	19	7	548	5	542	4e-47	186
rs:WP_026624798	DNA topoisomerase III [Eggerthia catenaformis].	28.52	554	323	17	5	539	3	502	4e-47	184
rs:WP_043895884	DNA topoisomerase III [Porphyromonas gingivalis].	27.22	540	348	17	7	531	2	511	4e-47	186
rs:WP_004054601	DNA topoisomerase III [Eubacterium plexicaudatum].	28.52	568	337	17	7	549	4	527	5e-47	186
rs:WP_007754171	MULTISPECIES: DNA topoisomerase I [Bacteroides].	29.09	574	345	20	4	552	1	537	5e-47	186
rs:WP_008063202	DNA topoisomerase III [Methyloversatilis universalis].	28.00	550	354	16	7	531	6	538	5e-47	187
rs:WP_038605799	DNA topoisomerase I [Bacteroides dorei].	29.09	574	345	20	4	552	1	537	5e-47	186
rs:WP_037612612	DNA topoisomerase [Streptococcus sp. OBRC6].	27.83	618	377	18	4	601	2	570	5e-47	184
rs:WP_034757415	DNA topoisomerase III [Chryseobacterium sp. OV259].	28.99	545	331	18	8	531	5	514	5e-47	186
tr:G4M7R3_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.88	581	380	17	7	568	6	566	5e-47	187
rs:WP_009259780	DNA topoisomerase III [Lachnospiraceae bacterium 7_1_58FAA].	28.16	554	342	17	7	546	5	516	5e-47	186
rs:WP_027374258	MULTISPECIES: DNA topoisomerase III [Chryseobacterium].	29.43	547	329	20	8	531	5	517	5e-47	186
rs:WP_012365004	DNA topoisomerase III [Burkholderia ambifaria].	27.99	561	369	15	7	550	6	548	5e-47	187
rs:WP_006441522	DNA topoisomerase III [[Clostridium] hylemonae].	27.88	599	371	22	8	554	7	596	5e-47	186
rs:WP_035628096	DNA topoisomerase III [Lachnospiraceae bacterium C6A11].	27.27	616	372	17	7	554	5	612	5e-47	186
rs:WP_047338624	DNA topoisomerase III [Enterococcus cecorum].	28.06	556	336	20	7	550	5	508	5e-47	186
rs:WP_034208701	DNA topoisomerase III [Burkholderia cepacia].	28.16	561	368	15	7	550	6	548	5e-47	187
rs:WP_041592301	DNA topoisomerase III [Terribacillus aidingensis].	28.57	602	389	18	8	603	6	572	5e-47	186
rs:WP_047210003	DNA topoisomerase [Streptococcus agalactiae].	28.88	561	343	17	4	550	2	520	5e-47	184
rs:WP_005875378	DNA topoisomerase III [Porphyromonas gingivalis].	27.22	540	348	17	7	531	2	511	5e-47	186
rs:WP_043894242	DNA topoisomerase III [Porphyromonas gingivalis].	27.22	540	348	17	7	531	2	511	5e-47	186
rs:WP_004342332	DNA topoisomerase III [Prevotella buccae].	28.42	556	331	20	7	531	2	521	5e-47	186
rs:WP_039445782	DNA topoisomerase III [Porphyromonas gulae].	27.04	540	349	18	7	531	2	511	5e-47	186
tr:S9BCI7_STRAG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.34	554	320	20	7	539	41	538	5e-47	185
rs:WP_021993625	DNA topoisomerase III [Prevotella sp. CAG:487].	28.31	551	331	17	7	531	2	514	5e-47	186
rs:WP_045785422	DNA topoisomerase III [Ralstonia mannitolilytica].	27.81	622	403	18	7	606	6	603	5e-47	187
tr:X0NXT2_PHOLE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.32	432	280	10	131	548	15	439	5e-47	184
rs:WP_017650048	DNA topoisomerase [Streptococcus agalactiae].	27.81	561	349	16	4	550	2	520	5e-47	184
rs:WP_014224886	DNA topoisomerase III [Tannerella forsythia].	28.10	541	341	17	8	531	5	514	5e-47	186
rs:WP_033911109	conjugal transfer protein TraE, partial [Neisseria gonorrhoeae].	26.89	569	373	15	8	548	6	559	5e-47	184
rs:WP_008975260	DNA topoisomerase III [Lachnospiraceae bacterium 6_1_37FAA].	27.53	574	361	19	5	534	4	566	5e-47	186
rs:WP_010113203	DNA topoisomerase III [Burkholderia oklahomensis].	27.99	561	369	15	7	550	6	548	6e-47	187
rs:WP_006750079	DNA topoisomerase III [Burkholderia ambifaria].	27.99	561	369	15	7	550	6	548	6e-47	187
rs:WP_011187245	DNA topoisomerase III [Campylobacter jejuni].	26.37	584	377	16	8	559	5	567	6e-47	186
tr:A0A069DAW1_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.88	625	395	19	5	599	3	595	6e-47	186
rs:WP_011658238	DNA topoisomerase III [Burkholderia ambifaria].	27.99	561	369	15	7	550	6	548	6e-47	187
rs:WP_001235773	MULTISPECIES: DNA topoisomerase III [Escherichia].	27.18	563	373	14	7	543	4	555	6e-47	186
rs:WP_001549937	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	28.65	569	357	15	7	543	4	555	6e-47	186
rs:WP_039419614	DNA topoisomerase III [Porphyromonas gulae].	27.04	540	349	18	7	531	2	511	6e-47	186
rs:WP_032459396	DNA topoisomerase III [Streptococcus agalactiae].	28.34	554	320	20	7	539	6	503	6e-47	184
rs:WP_017876401	hypothetical protein [Janthinobacterium sp. CG3].	27.32	560	374	17	7	547	4	549	6e-47	186
rs:WP_007416564	DNA topoisomerase III [Pedosphaera parvula].	27.62	630	402	22	7	606	6	611	6e-47	186
rs:WP_004346762	DNA topoisomerase III [Prevotella buccae].	28.78	556	329	20	7	531	2	521	6e-47	186
rs:WP_010899528	DNA topoisomerase III [Bacillus halodurans].	28.77	570	369	18	45	599	46	593	6e-47	186
rs:WP_021034341	hypothetical protein [Campylobacter coli].	26.37	584	377	16	8	559	5	567	6e-47	186
rs:WP_023984861	DNA topoisomerase III [Prevotella oralis].	28.47	548	334	17	7	531	2	514	6e-47	186
rs:WP_037616756	DNA topoisomerase [Streptococcus sinensis].	28.24	563	344	18	4	550	2	520	6e-47	184
rs:WP_014895687	DNA topoisomerase III [Burkholderia cepacia].	28.34	561	367	15	7	550	6	548	6e-47	187
rs:WP_021801651	DNA topoisomerase III [Clostridium intestinale].	28.60	556	357	16	8	534	7	551	6e-47	185
rs:WP_004628306	DNA topoisomerase III [Ralstonia pickettii].	28.38	599	371	20	7	577	6	574	6e-47	187
rs:WP_002779644	MULTISPECIES: DNA topoisomerase III [Campylobacter].	26.37	584	377	16	8	559	5	567	6e-47	186
rs:WP_016355620	DNA topoisomerase [Pseudomonas migulae].	26.35	554	356	15	35	546	33	576	6e-47	186
rs:WP_043275216	DNA topoisomerase III [Burkholderia pseudomallei].	28.16	561	368	15	7	550	6	548	6e-47	187
rs:WP_038784157	DNA topoisomerase III [Burkholderia pseudomallei].	28.16	561	368	15	7	550	6	548	6e-47	187
rs:WP_042165346	DNA topoisomerase III [Paenibacillus sp. G1].	27.87	574	330	17	7	544	5	530	6e-47	186
tr:E7RZM8_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.65	569	356	19	7	550	6	549	6e-47	187
rs:WP_035987223	DNA topoisomerase III [Burkholderia caribensis].	28.34	561	367	16	7	550	6	548	6e-47	187
rs:WP_009530372	DNA topoisomerase III [Peptostreptococcaceae bacterium OBRC8].	26.97	608	373	18	7	590	4	564	6e-47	186
rs:WP_037288732	DNA topoisomerase III [Saccharibacillus sacchari].	25.63	632	415	15	7	603	4	615	6e-47	186
rs:WP_043894827	DNA topoisomerase III [Porphyromonas gingivalis].	27.22	540	348	17	7	531	2	511	6e-47	185
rs:WP_042257786	DNA topoisomerase, partial [Butyrivibrio proteoclasticus].	27.58	591	361	20	7	544	6	582	6e-47	185
rs:WP_023612253	DNA topoisomerase III [Streptococcus pyogenes].	28.39	553	321	19	7	539	6	503	6e-47	184
rs:WP_038787866	DNA topoisomerase III [Burkholderia pseudomallei].	28.16	561	368	15	7	550	6	548	6e-47	187
rs:WP_007411728	DNA topoisomerase III [Prevotella sp. MSX73].	28.78	556	329	20	7	531	2	521	6e-47	186
rs:WP_015617751	topoisomerase IA [Clostridium pasteurianum].	27.21	599	386	17	7	579	5	579	7e-47	186
rs:WP_039086231	conjugal transfer protein TraE [Gallibacterium anatis].	26.94	553	363	11	7	531	4	543	7e-47	186
rs:WP_003034176	DNA topoisomerase III [Streptococcus anginosus].	27.68	542	339	17	7	539	4	501	7e-47	184
rs:WP_042677102	DNA topoisomerase III, partial [Pantoea sp. B40].	31.93	379	231	11	170	531	30	398	7e-47	181
rs:WP_038781805	DNA topoisomerase III [Burkholderia pseudomallei].	28.16	561	368	15	7	550	6	548	7e-47	186
rs:WP_039439757	DNA topoisomerase III [Porphyromonas gulae].	27.04	540	349	18	7	531	2	511	7e-47	185
rs:WP_024004637	DNA topoisomerase III [Advenella kashmirensis].	29.77	561	338	19	5	534	4	539	7e-47	187
rs:WP_043889999	DNA topoisomerase III [Porphyromonas gingivalis].	27.86	542	342	18	7	531	2	511	7e-47	185
rs:WP_039417509	DNA topoisomerase III [Porphyromonas gingivalis].	27.22	540	348	17	7	531	2	511	7e-47	185
rs:WP_045499150	DNA topoisomerase III [Chryseobacterium sp. StRB126].	30.16	547	325	20	8	531	5	517	7e-47	186
rs:WP_039446752	DNA topoisomerase III [Porphyromonas gulae].	27.04	540	349	18	7	531	2	511	7e-47	185
rs:WP_012492332	MULTISPECIES: DNA topoisomerase III [Burkholderia cepacia complex].	28.16	561	368	15	7	550	6	548	7e-47	186
rs:WP_024977063	DNA topoisomerase III [Ralstonia pickettii].	28.50	600	369	21	7	577	6	574	7e-47	187
rs:WP_039170259	conjugal transfer protein TraE [Gallibacterium anatis].	26.94	553	363	11	7	531	4	543	7e-47	186
rs:WP_034410032	DNA topoisomerase III, partial [Derxia gummosa].	28.47	583	356	19	3	550	2	558	7e-47	186
tr:A0A0E2LU45_PORGN	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERJ69010.1};	27.22	540	348	17	7	531	37	546	7e-47	185
rs:WP_033572488	DNA topoisomerase I [Bacteroides sp. UW].	28.69	582	337	21	4	552	1	537	7e-47	185
rs:WP_017772360	DNA topoisomerase III [Burkholderia kururiensis].	27.99	561	369	15	7	550	6	548	7e-47	187
rs:WP_046826025	DNA topoisomerase III [Tannerella forsythia].	27.36	541	345	16	8	531	5	514	7e-47	185
rs:WP_046200217	DNA topoisomerase III [Porphyromonas gulae].	27.31	542	345	18	7	531	2	511	7e-47	185
rs:WP_044906266	hypothetical protein, partial [Lachnospiraceae bacterium MC2017].	27.94	612	361	23	5	551	11	607	7e-47	185
rs:WP_000259055	DNA topoisomerase III [Streptococcus agalactiae].	28.98	566	336	18	4	550	2	520	7e-47	184
rs:WP_038758558	DNA topoisomerase III [Burkholderia pseudomallei].	28.16	561	368	15	7	550	6	548	7e-47	186
rs:WP_046835606	DNA topoisomerase III, partial [Pseudomonas amygdali].	30.97	352	225	7	213	549	4	352	7e-47	179
rs:WP_015695070	DNA topoisomerase III [Melissococcus plutonius].	27.85	553	340	18	7	550	7	509	7e-47	185
rs:WP_043894029	DNA topoisomerase III [Porphyromonas gingivalis].	27.22	540	348	17	7	531	2	511	7e-47	185
rs:WP_005307127	DNA topoisomerase III [Photobacterium damselae].	27.61	547	356	15	7	530	4	533	7e-47	186
rs:WP_009927580	DNA topoisomerase III [Burkholderia pseudomallei].	28.16	561	368	15	7	550	6	548	7e-47	186
rs:WP_038773172	DNA topoisomerase III [Burkholderia pseudomallei].	28.16	561	368	15	7	550	6	548	7e-47	186
rs:WP_038709762	DNA topoisomerase III [Burkholderia sp. lig30].	27.81	561	370	15	7	550	6	548	7e-47	186
rs:WP_011353576	DNA topoisomerase III [Burkholderia lata].	26.77	620	412	17	7	603	6	606	7e-47	186
rs:WP_036739241	DNA topoisomerase [Peptoniphilus sp. BV3C26].	28.21	553	322	19	7	539	6	503	7e-47	184
rs:WP_007581951	MULTISPECIES: DNA topoisomerase III [Burkholderia].	28.34	561	367	16	7	550	6	548	8e-47	186
rs:WP_016440647	DNA topoisomerase III [Coprococcus sp. HPP0048].	27.87	574	359	20	5	534	4	566	8e-47	185
rs:WP_012436841	MULTISPECIES: DNA topoisomerase III [Ralstonia].	28.38	599	371	20	7	577	6	574	8e-47	186
rs:WP_004537740	DNA topoisomerase III [Burkholderia pseudomallei].	28.16	561	368	15	7	550	6	548	8e-47	186
rs:WP_023940994	MULTISPECIES: DNA topoisomerase III [Porphyromonas].	27.41	591	379	17	8	579	5	564	8e-47	185
rs:WP_027101633	DNA topoisomerase III [Comamonadaceae bacterium URHA0028].	28.10	612	376	19	1	568	1	592	8e-47	187
tr:D6DKA4_CLOSC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.87	603	347	18	8	535	7	590	8e-47	185
rs:WP_009979581	DNA topoisomerase III [Burkholderia pseudomallei].	28.16	561	368	15	7	550	6	548	8e-47	186
rs:WP_020998778	DNA topoisomerase [Streptococcus intermedius].	28.39	553	321	18	7	539	4	501	8e-47	184
rs:WP_025653856	DNA topoisomerase III [Clostridiales bacterium VE202-21].	27.14	560	352	16	7	550	5	524	8e-47	185
rs:WP_038793625	DNA topoisomerase III [Burkholderia pseudomallei].	28.16	561	368	15	7	550	6	548	8e-47	186
rs:WP_043992340	DNA topoisomerase III, partial [Vibrio cholerae].	29.03	434	261	10	135	539	3	418	8e-47	183
rs:WP_017759289	DNA topoisomerase III [Pseudacidovorax intermedius].	29.11	615	360	27	5	568	4	593	8e-47	187
rs:WP_000259051	DNA topoisomerase III [Streptococcus agalactiae].	27.36	625	373	22	4	602	2	571	8e-47	184
rs:WP_043299896	DNA topoisomerase III [Burkholderia sp. TSV202].	28.16	561	368	15	7	550	6	548	8e-47	186
rs:WP_004189734	DNA topoisomerase III [Burkholderia mallei].	28.16	561	368	15	7	550	6	548	8e-47	186
rs:WP_004523103	DNA topoisomerase III [Burkholderia pseudomallei].	28.16	561	368	15	7	550	6	548	8e-47	186
rs:WP_009249295	DNA topoisomerase III [Lachnospiraceae bacterium 5_1_57FAA].	27.90	595	372	20	8	554	7	592	8e-47	185
tr:F5X8C0_PORGT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:BAK24552.1};	27.86	542	342	18	7	531	17	526	8e-47	185
tr:W1R7K4_PORGN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ETA26501.1};	27.22	540	348	17	7	531	17	526	8e-47	185
tr:B2RH95_PORG3	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:BAG32740.1};	27.68	542	343	18	7	531	37	546	8e-47	185
rs:WP_009298985	MULTISPECIES: DNA topoisomerase III [Clostridiales].	26.95	564	350	16	7	549	4	526	8e-47	185
rs:WP_038798357	DNA topoisomerase III [Burkholderia pseudomallei].	28.16	561	368	15	7	550	6	548	8e-47	186
rs:WP_002587416	DNA topoisomerase III [[Clostridium] clostridioforme].	26.95	564	351	15	7	549	6	529	8e-47	185
rs:WP_043895468	DNA topoisomerase III [Porphyromonas gingivalis].	27.86	542	342	18	7	531	2	511	8e-47	185
rs:WP_024973868	DNA topoisomerase III [Ralstonia pickettii].	28.38	599	371	20	7	577	6	574	8e-47	186
rs:WP_040296029	DNA topoisomerase III [Barnesiella intestinihominis].	27.74	530	349	14	8	531	5	506	9e-47	185
rs:WP_038729298	DNA topoisomerase III [Burkholderia pseudomallei].	28.16	561	368	15	7	550	6	548	9e-47	186
rs:WP_041098558	DNA topoisomerase III [Bacillus badius].	29.23	568	351	19	5	548	3	543	9e-47	185
rs:WP_004200734	MULTISPECIES: DNA topoisomerase III [pseudomallei group].	28.16	561	368	15	7	550	6	548	9e-47	186
rs:WP_011850901	DNA topoisomerase III [Burkholderia pseudomallei].	28.16	561	368	15	7	550	6	548	9e-47	186
rs:WP_004525850	MULTISPECIES: DNA topoisomerase III [Burkholderia].	28.16	561	368	15	7	550	6	548	9e-47	186
rs:WP_021992003	DNA topoisomerase III [Prevotella sp. CAG:1092].	28.60	556	333	22	7	531	2	524	9e-47	185
tr:U7UNB0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.21	553	322	19	7	539	30	527	9e-47	184
rs:WP_044879959	DNA topoisomerase III [Paenibacillus sp. IHBB 10380].	27.94	630	382	21	5	599	3	595	9e-47	185
rs:WP_026504840	DNA topoisomerase III [Butyrivibrio sp. NC3005].	27.18	618	367	19	7	582	4	580	9e-47	184
rs:WP_040068217	DNA topoisomerase III [Aeromonas veronii].	27.38	577	378	13	7	557	7	568	9e-47	185
rs:WP_023937515	DNA topoisomerase III [Porphyromonas crevioricanis].	27.41	591	379	17	8	579	5	564	9e-47	185
rs:WP_036803215	hypothetical protein [Pontibacillus halophilus].	27.31	520	347	12	43	544	31	537	9e-47	185
tr:W7WV89_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.87	379	235	9	171	530	9	379	9e-47	183
rs:WP_006759746	DNA topoisomerase III [Burkholderia ambifaria].	28.34	561	367	16	7	550	6	548	9e-47	186
tr:D4JPB1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.35	611	374	16	7	553	6	604	9e-47	188
tr:I7IL22_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.02	572	356	18	3	543	2	554	9e-47	186
rs:WP_025399361	DNA topoisomerase III [Campylobacter coli].	26.37	584	377	16	8	559	5	567	9e-47	185
rs:WP_041617834	DNA topoisomerase III, partial [Paenibacillus mucilaginosus].	27.29	623	385	18	5	590	3	594	9e-47	184
rs:WP_028884328	DNA topoisomerase III [Taylorella asinigenitalis].	29.02	572	356	18	3	543	2	554	9e-47	186
rs:WP_025755768	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	27.18	563	373	14	7	543	4	555	9e-47	185
rs:WP_034190221	DNA topoisomerase III [Burkholderia cenocepacia].	27.99	561	369	15	7	550	6	548	9e-47	186
rs:WP_043756124	DNA topoisomerase III [Thiorhodococcus sp. AK35].	28.72	564	343	18	4	539	2	534	9e-47	186
rs:WP_006268556	DNA topoisomerase [Streptococcus constellatus].	27.86	542	338	16	7	539	4	501	9e-47	184
rs:WP_011803324	DNA topoisomerase III [Polaromonas naphthalenivorans].	28.67	586	359	18	5	550	3	569	1e-46	187
rs:WP_022292366	DNA topoisomerase [Eubacterium rectale CAG:36].	26.35	611	374	16	7	553	6	604	1e-46	188
rs:WP_027788846	DNA topoisomerase III [Burkholderia cepacia].	27.99	561	369	15	7	550	6	548	1e-46	186
rs:WP_044995209	DNA topoisomerase III [Lachnospiraceae bacterium JC7].	27.36	625	377	21	7	568	5	615	1e-46	184
rs:WP_036890366	DNA topoisomerase III [Porphyromonas crevioricanis].	27.41	591	379	17	8	579	5	564	1e-46	184
rs:WP_026462624	DNA topoisomerase III [Adhaeribacter aquaticus].	28.00	550	332	19	8	531	5	516	1e-46	186
rs:WP_043012959	DNA topoisomerase III [Campylobacter jejuni].	26.37	584	377	16	8	559	5	567	1e-46	185
rs:WP_026882027	DNA topoisomerase [Clostridium akagii].	27.12	601	387	17	7	579	5	582	1e-46	185
rs:WP_004083334	DNA topoisomerase III [Clostridium sp. ASF502].	28.47	555	334	18	7	539	4	517	1e-46	185
rs:WP_023859599	DNA topoisomerase III [Lactobacillus equi].	29.36	562	318	22	7	550	6	506	1e-46	185
rs:WP_017771170	MULTISPECIES: DNA topoisomerase III [Streptococcus].	26.73	621	382	21	4	602	2	571	1e-46	184
tr:U2LGV2_PORGN	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERJ88694.1};	27.86	542	342	18	7	531	17	526	1e-46	185
rs:WP_026969602	DNA topoisomerase III [Algoriphagus terrigena].	28.46	534	339	16	8	531	5	505	1e-46	185
rs:WP_043834996	DNA topoisomerase III [Roseomonas aerilata].	26.24	545	354	12	7	531	6	522	1e-46	185
rs:WP_016184912	DNA topoisomerase III [Enterococcus sulfureus].	28.75	553	330	20	7	548	5	504	1e-46	185
rs:WP_007886640	DNA topoisomerase III [Roseburia inulinivorans].	26.67	570	356	15	1	549	1	529	1e-46	185
tr:Q3JXE5_BURP1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.16	561	368	15	7	550	42	584	1e-46	186
rs:WP_006803319	DNA topoisomerase III [Helicobacter winghamensis].	25.79	605	394	16	7	575	4	589	1e-46	185
rs:WP_007845711	DNA topoisomerase I [Bacteroides dorei].	28.92	574	346	20	4	552	1	537	1e-46	185
rs:WP_009092112	DNA topoisomerase [Elizabethkingia anophelis].	28.55	620	374	19	4	601	1	573	1e-46	185
rs:WP_025478641	DNA topoisomerase [Enterococcus faecium].	29.33	583	370	17	5	563	3	567	1e-46	185
rs:WP_029175409	DNA topoisomerase [Streptococcus suis].	28.57	567	337	17	4	550	2	520	1e-46	184
rs:WP_024739084	DNA topoisomerase III [Clostridiales bacterium VE202-16].	26.60	564	352	15	7	549	4	526	1e-46	185
tr:B1HHD0_BURPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.16	561	368	15	7	550	43	585	1e-46	186
tr:K0WYG1_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJZ64257.1};	27.74	530	349	14	8	531	35	536	1e-46	185
tr:C4Z0Y0_EUBE2	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.77	579	358	21	8	532	24	590	1e-46	185
rs:WP_002570999	DNA topoisomerase III [[Clostridium] bolteae].	26.42	564	353	15	7	549	6	528	1e-46	185
rs:WP_009529996	DNA topoisomerase III [Peptostreptococcaceae bacterium CM5].	27.29	612	386	20	7	606	6	570	1e-46	183
rs:WP_041688620	DNA topoisomerase III [[Eubacterium] eligens].	26.63	582	361	21	5	532	4	573	1e-46	184
rs:WP_043184744	DNA topoisomerase III [Burkholderia cepacia].	26.77	620	412	17	7	603	6	606	1e-46	186
tr:A3NQ18_BURP0	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.16	561	368	15	7	550	43	585	1e-46	186
rs:WP_042299241	DNA topoisomerase III [Burkholderia kururiensis].	27.99	561	369	15	7	550	6	548	1e-46	186
tr:A0A0D8YIF7_BACLI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KJH56470.1};	29.70	532	329	20	7	531	5	498	1e-46	185
rs:WP_017722920	DNA topoisomerase III [Staphylococcus xylosus].	26.06	564	378	16	7	559	5	540	1e-46	185
rs:WP_010803479	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	28.67	579	341	20	4	552	1	537	1e-46	185
rs:WP_022097691	DNA topoisomerase [Eubacterium eligens CAG:72].	26.64	578	360	20	8	532	24	590	1e-46	184
rs:WP_045366128	DNA topoisomerase III, partial [bacterium endosymbiont of Mortierella elongata FMR23-6].	28.60	563	363	18	7	550	6	548	1e-46	186
tr:A0A070C158_BURCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.61	620	413	17	7	603	6	606	1e-46	186
rs:WP_016264956	DNA topoisomerase III [Lactobacillus sakei].	28.70	561	326	20	7	550	6	509	1e-46	184
rs:WP_044982516	hypothetical protein, partial [Lachnospiraceae bacterium NK4A144].	28.15	604	353	23	5	543	11	598	1e-46	184
rs:WP_044377079	DNA topoisomerase III, partial [Escherichia coli].	28.12	480	318	13	8	471	5	473	1e-46	182
rs:WP_019915921	DNA topoisomerase III [Methyloversatilis sp. FAM1].	28.83	555	345	20	7	531	6	540	1e-46	186
rs:WP_010181876	DNA topoisomerase III [Aquimarina agarilytica].	28.83	548	334	18	8	531	5	520	1e-46	185
rs:WP_007482184	DNA topoisomerase III [Bacteroides salyersiae].	27.91	541	341	15	7	531	2	509	1e-46	184
rs:WP_007139586	DNA topoisomerase [Flavobacterium frigoris].	28.47	548	342	17	4	531	1	518	1e-46	184
rs:WP_042626312	DNA topoisomerase III [Burkholderia glumae].	27.81	561	370	15	7	550	6	548	1e-46	186
rs:WP_007705937	DNA topoisomerase III [[Clostridium] asparagiforme].	27.19	559	353	16	7	550	5	524	1e-46	184
rs:WP_006566846	DNA topoisomerase III [Anaerostipes caccae].	26.49	589	379	20	8	554	12	588	1e-46	184
rs:WP_034713734	DNA topoisomerase III [Chryseobacterium soli].	29.04	544	332	20	8	531	5	514	1e-46	184
rs:WP_043485858	hypothetical protein, partial [Holophaga foetida].	27.67	571	361	16	7	544	6	557	1e-46	184
rs:WP_047212299	DNA topoisomerase [Streptococcus agalactiae].	28.21	553	322	19	7	539	6	503	1e-46	183
rs:WP_042739088	DNA topoisomerase III [Staphylococcus gallinarum].	27.43	565	369	17	7	559	5	540	1e-46	184
tr:C6LDA7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.01	564	337	19	1	539	3	522	1e-46	184
rs:WP_035344579	DNA topoisomerase [Bacillus hemicellulosilyticus].	28.62	601	377	21	4	579	1	574	1e-46	184
tr:U7UHG3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.21	553	322	19	7	539	30	527	1e-46	183
rs:WP_018965808	DNA topoisomerase III [Porphyromonas gulae].	27.04	540	349	18	7	531	2	511	1e-46	184
rs:WP_016289907	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	27.67	571	344	15	7	548	6	536	1e-46	184
rs:WP_034957209	DNA topoisomerase III, partial [Glomeribacter sp. 1016415].	28.60	563	363	18	7	550	6	548	1e-46	185
rs:WP_009445426	DNA topoisomerase III [Lachnospiraceae bacterium oral taxon 082].	27.50	589	365	22	8	550	6	578	1e-46	184
rs:WP_031554387	DNA topoisomerase III, partial [Oribacterium sp. FC2011].	26.58	632	382	21	7	568	5	624	1e-46	184
rs:WP_009767084	DNA topoisomerase [Moraxella macacae].	27.07	580	368	18	7	548	4	566	1e-46	185
rs:WP_023916854	DNA topoisomerase III [Streptococcus sanguinis].	27.77	569	343	18	4	552	2	522	1e-46	183
rs:WP_009535407	DNA topoisomerase III [Oribacterium parvum].	28.08	609	371	23	7	601	4	559	1e-46	183
rs:WP_002801286	DNA topoisomerase III, partial [Campylobacter coli].	26.20	584	378	16	8	559	5	567	1e-46	184
rs:WP_039432547	DNA topoisomerase III [Porphyromonas gulae].	26.85	540	350	18	7	531	2	511	1e-46	184
rs:WP_021935895	DNA topoisomerase III [Bacteroides sp. CAG:189].	27.91	541	341	15	7	531	2	509	1e-46	184
rs:WP_039830311	DNA topoisomerase III, partial [Pandoraea sp. B-6].	28.60	598	367	22	7	571	6	576	1e-46	186
rs:WP_038762203	DNA topoisomerase III [Burkholderia pseudomallei].	28.29	562	366	16	7	550	6	548	1e-46	186
rs:WP_007391818	MULTISPECIES: DNA topoisomerase [Firmicutes].	28.21	553	322	19	7	539	6	503	1e-46	183
rs:WP_039427007	DNA topoisomerase III [Porphyromonas gulae].	27.31	542	345	18	7	531	2	511	1e-46	184
tr:W1WUK7_9ZZZZ	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:ETJ21606.1}; Flags: Fragment;	26.99	578	356	15	56	606	6	544	1e-46	184
rs:WP_034579773	DNA topoisomerase [Kallipyga massiliensis].	28.21	553	322	19	7	539	6	503	1e-46	183
rs:WP_004820017	DNA topoisomerase [Peptoniphilus indolicus].	27.12	542	342	16	7	539	4	501	1e-46	183
rs:WP_008639302	MULTISPECIES: DNA topoisomerase III [Bacillaceae].	28.47	555	360	14	7	544	6	540	1e-46	184
rs:WP_014110704	DNA topoisomerase III [Taylorella asinigenitalis].	29.02	572	356	18	3	543	2	554	1e-46	185
rs:WP_023152731	DNA topoisomerase [Eubacterium brachy].	27.15	641	404	19	7	601	5	628	2e-46	184
rs:WP_022207365	DNA topoisomerase [Eubacterium sp. CAG:252].	26.36	588	367	19	8	539	7	584	2e-46	184
rs:WP_021749501	MULTISPECIES: DNA topoisomerase [Oscillibacter].	28.57	560	345	20	7	550	4	524	2e-46	184
rs:WP_019653808	DNA topoisomerase III [Variovorax paradoxus].	27.69	614	372	22	5	568	4	595	2e-46	186
rs:WP_042586599	DNA topoisomerase III [Burkholderia sp. MSHR3999].	27.99	561	369	15	7	550	6	548	2e-46	186
rs:WP_021932094	DNA topoisomerase III [Tannerella sp. CAG:118].	28.75	546	332	21	8	531	5	515	2e-46	184
rs:WP_043043642	hypothetical protein, partial [Streptococcus equi].	27.70	556	363	12	7	543	4	539	2e-46	184
rs:WP_025271724	DNA topoisomerase [Streptococcus anginosus].	27.67	618	378	18	4	601	2	570	2e-46	183
rs:WP_036625876	DNA topoisomerase III [Paenibacillus macerans].	27.84	582	343	20	5	559	3	534	2e-46	184
rs:WP_047211463	DNA topoisomerase [Streptococcus agalactiae].	28.04	542	337	16	7	539	4	501	2e-46	183
rs:WP_032543297	DNA topoisomerase I [Bacteroides fragilis].	28.69	582	337	21	4	552	1	537	2e-46	184
rs:WP_034433748	DNA topoisomerase [Clostridiales bacterium S5-A14a].	28.21	553	322	19	7	539	6	503	2e-46	183
rs:WP_034686218	DNA topoisomerase III [Chryseobacterium piperi].	28.81	545	333	20	8	531	5	515	2e-46	184
rs:WP_007856134	DNA topoisomerase III, partial [Acidovorax sp. CF316].	28.17	607	367	21	5	568	4	584	2e-46	186
rs:WP_009756925	DNA topoisomerase III [Lachnospiraceae bacterium 2_1_46FAA].	28.27	612	369	24	8	570	7	597	2e-46	184
rs:WP_007840343	MULTISPECIES: DNA topoisomerase III [Chryseobacterium].	28.86	544	334	19	8	531	5	515	2e-46	184
rs:WP_029054036	DNA topoisomerase III [Sporosarcina ureae].	29.22	551	360	15	7	544	5	538	2e-46	184
rs:WP_032560966	DNA topoisomerase I [Bacteroides fragilis].	27.60	616	380	22	4	591	1	578	2e-46	184
rs:WP_024538446	DNA topoisomerase III [Comamonas badia].	29.34	593	347	24	3	550	2	567	2e-46	186
rs:WP_008679608	DNA topoisomerase III [Clostridium sp. 7_2_43FAA].	28.01	589	367	23	5	553	4	575	2e-46	184
rs:WP_033480338	DNA topoisomerase, partial [Xanthomonas axonopodis].	27.18	504	326	13	72	548	2	491	2e-46	183
rs:WP_028071503	DNA topoisomerase I [Sphingobacterium thalpophilum].	28.09	559	340	17	4	531	1	528	2e-46	184
rs:WP_022375749	DNA topoisomerase III [Firmicutes bacterium CAG:270].	27.80	590	373	22	8	555	6	584	2e-46	184
rs:WP_016295879	DNA topoisomerase III [Lachnospiraceae bacterium M18-1].	27.53	574	338	18	7	550	4	529	2e-46	184
rs:WP_039438134	DNA topoisomerase III [Porphyromonas gulae].	26.85	540	350	18	7	531	2	511	2e-46	184
rs:WP_040955857	DNA topoisomerase [Virgibacillus sp. SK37].	28.73	616	392	19	7	597	4	597	2e-46	184
tr:A0A0B6S0Y1_BURGL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.81	561	370	15	7	550	28	570	2e-46	186
rs:WP_042987762	DNA topoisomerase I [Bacteroides fragilis].	27.54	621	374	22	4	591	1	578	2e-46	184
rs:WP_009264837	DNA topoisomerase III [Lachnospiraceae bacterium 5_1_63FAA].	27.41	591	376	20	7	555	5	584	2e-46	184
rs:WP_010090307	DNA topoisomerase III [Burkholderia ubonensis].	27.99	561	369	15	7	550	6	548	2e-46	185
rs:WP_028910324	DNA topoisomerase III [Prevotella sp. AGR2160].	28.98	566	331	19	7	531	2	537	2e-46	184
rs:WP_011282541	DNA topoisomerase III [Pseudomonas savastanoi].	26.57	591	390	15	4	565	1	576	2e-46	184
rs:WP_040782654	DNA topoisomerase III [Marvinbryantia formatexigens].	28.32	558	331	19	7	539	4	517	2e-46	184
rs:WP_022361881	DNA topoisomerase [Bacteroides pectinophilus CAG:437].	26.97	623	368	19	5	553	4	613	2e-46	184
rs:WP_036647111	DNA topoisomerase III [Paenibacillus pini].	26.98	630	387	20	5	599	3	594	2e-46	184
rs:WP_032587100	DNA topoisomerase I [Bacteroides fragilis].	27.54	621	374	22	4	591	1	578	2e-46	184
rs:WP_042967424	DNA topoisomerase III, partial [Burkholderia glumae].	27.99	561	369	15	7	550	6	548	2e-46	185
rs:WP_029706781	DNA topoisomerase III [Rhodoferax saidenbachensis].	28.26	591	352	20	5	550	3	566	2e-46	186
tr:D4CEE7_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.70	603	348	18	8	535	22	605	2e-46	184
rs:WP_044666441	DNA topoisomerase [Streptococcus suis].	28.60	542	334	17	7	539	6	503	2e-46	182
tr:W1U0R1_STRAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.21	553	322	19	7	539	41	538	2e-46	183
rs:WP_039204385	DNA topoisomerase III, partial [Burkholderia glumae].	27.99	561	369	15	7	550	6	548	2e-46	185
rs:WP_032587447	DNA topoisomerase III [Campylobacter jejuni].	26.20	584	378	16	8	559	5	567	2e-46	184
rs:WP_018312052	DNA topoisomerase III [Cupriavidus sp. UYPR2.512].	28.82	569	357	18	7	550	6	551	2e-46	185
rs:WP_004368552	DNA topoisomerase III [Prevotella oralis].	28.47	548	334	17	7	531	2	514	2e-46	184
rs:WP_035978137	DNA topoisomerase III, partial [Burkholderia glumae].	27.99	561	369	15	7	550	6	548	2e-46	185
rs:WP_039677235	DNA topoisomerase [Streptococcus constellatus].	27.90	552	325	17	7	539	4	501	2e-46	182
rs:WP_006416665	DNA topoisomerase III [Burkholderia multivorans].	27.99	561	369	15	7	550	6	548	2e-46	185
rs:WP_006401840	DNA topoisomerase III [Burkholderia multivorans].	27.99	561	369	15	7	550	6	548	2e-46	185
rs:WP_019721174	DNA topoisomerase III [Bacillus coagulans].	27.87	549	332	17	7	540	5	504	2e-46	184
rs:WP_015391084	DNA topoisomerase 3 [Clostridium saccharoperbutylacetonicum].	27.42	598	387	17	7	579	5	580	2e-46	184
rs:WP_016426347	DNA topoisomerase III [Staphylococcus sp. HGB0015].	28.37	564	364	18	7	559	5	539	2e-46	184
rs:WP_015877326	DNA topoisomerase III [Burkholderia glumae].	27.99	561	369	15	7	550	6	548	2e-46	185
tr:A0A078BLX7_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.81	486	307	12	97	561	12	479	2e-46	183
rs:WP_045715460	DNA topoisomerase III, partial [Salmonella enterica].	31.51	365	234	9	200	552	2	362	2e-46	180
rs:WP_025146083	hypothetical protein [Sphingobacterium sp. H1ai].	28.04	560	360	13	4	543	1	537	2e-46	184
rs:WP_016181416	DNA topoisomerase III [Enterococcus avium].	27.22	551	345	15	7	550	5	506	2e-46	184
rs:WP_016249872	DNA topoisomerase III [Enterococcus casseliflavus].	28.60	556	366	15	5	544	3	543	2e-46	184
rs:WP_006844208	DNA topoisomerase I [Dysgonomonas mossii].	28.00	575	359	17	7	558	4	546	2e-46	184
rs:WP_017768091	DNA topoisomerase III [Streptococcus agalactiae].	27.65	622	375	23	4	602	2	571	2e-46	182
rs:WP_044931349	DNA topoisomerase III [Clostridium sp. M62/1].	26.70	603	348	18	8	535	7	590	2e-46	184
rs:WP_028889542	DNA topoisomerase III [Tenacibaculum ovolyticum].	27.66	535	343	17	8	531	5	506	2e-46	184
rs:WP_002595170	DNA topoisomerase III [[Clostridium] clostridioforme].	27.39	566	347	15	7	550	6	529	2e-46	184
rs:WP_033125583	DNA topoisomerase III [Eubacterium sp. ER2].	27.45	623	365	22	8	554	7	618	2e-46	184
rs:WP_019393159	MULTISPECIES: DNA topoisomerase [Bacillus].	27.39	617	404	18	7	601	4	598	2e-46	184
rs:WP_009673239	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	26.60	579	345	19	3	550	2	531	2e-46	184
rs:WP_025194606	DNA topoisomerase III [Streptococcus agalactiae].	28.75	553	319	19	7	539	6	503	2e-46	182
tr:A0A022NBM7_ENTMU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.89	563	327	21	7	550	5	507	2e-46	184
rs:WP_004039093	DNA topoisomerase III [Clostridium sp. ASF356].	26.38	561	354	17	7	550	4	522	2e-46	184
rs:WP_043924753	hypothetical protein [Bacillus thuringiensis].	26.26	537	333	13	23	532	7	507	2e-46	184
rs:WP_018919556	DNA topoisomerase III [Prevotella oris].	28.57	574	330	20	7	531	2	544	2e-46	184
rs:WP_034982849	DNA topoisomerase III [Lactobacillus salivarius].	29.11	560	324	21	7	550	5	507	2e-46	184
rs:WP_003042371	DNA topoisomerase III [Streptococcus anginosus].	27.90	552	325	18	7	539	4	501	3e-46	182
rs:WP_011237506	DNA topoisomerase III [Aromatoleum aromaticum].	29.37	555	345	19	7	536	6	538	3e-46	185
rs:WP_035587590	DNA topoisomerase III [Elizabethkingia anophelis].	28.84	541	335	18	8	531	5	512	3e-46	184
rs:WP_008816736	DNA topoisomerase III [Erysipelotrichaceae bacterium 6_1_45].	26.77	564	351	15	7	549	4	526	3e-46	184
rs:WP_039429215	DNA topoisomerase III [Porphyromonas sp. COT-052 OH4946].	27.04	540	349	18	7	531	2	511	3e-46	184
rs:WP_002506961	DNA topoisomerase III [Staphylococcus sp. OJ82].	26.12	582	355	17	7	559	5	540	3e-46	184
rs:WP_024430099	DNA topoisomerase III [Burkholderia pseudomallei].	28.29	562	366	16	7	550	6	548	3e-46	185
rs:WP_000259047	MULTISPECIES: DNA topoisomerase III [Streptococcus].	27.65	622	375	23	4	602	2	571	3e-46	182
rs:WP_036723764	DNA topoisomerase III, partial [Paenibacillus forsythiae].	27.43	565	349	18	5	539	3	536	3e-46	183
rs:WP_031356953	DNA topoisomerase III [Burkholderia sordidicola].	27.41	580	384	16	7	568	6	566	3e-46	185
rs:WP_021966453	DNA topoisomerase III [Clostridium sp. CAG:149].	26.70	603	348	18	8	535	7	590	3e-46	184
rs:WP_029200156	DNA topoisomerase III [Oribacterium sp. NK2B42].	26.51	630	385	20	7	568	5	624	3e-46	183
rs:WP_004377279	DNA topoisomerase III [Prevotella oris].	28.57	574	330	20	7	531	2	544	3e-46	184
rs:WP_014568628	DNA topoisomerase III [Lactobacillus salivarius].	29.11	560	324	20	7	550	5	507	3e-46	184
rs:WP_011476268	DNA topoisomerase III [Lactobacillus salivarius].	29.36	562	320	22	7	550	5	507	3e-46	184
rs:WP_040177890	DNA topoisomerase III, partial [Klebsiella pneumoniae].	30.89	395	246	10	170	548	9	392	3e-46	181
rs:WP_010746590	DNA topoisomerase III [Enterococcus raffinosus].	27.44	554	340	16	7	550	5	506	3e-46	183
rs:WP_013085583	conjugal transfer protein TraE [Neisseria gonorrhoeae].	26.89	569	373	15	8	548	6	559	3e-46	184
rs:WP_047035846	DNA topoisomerase III [Lactobacillus salivarius].	29.29	560	323	21	7	550	5	507	3e-46	183
rs:WP_013859236	DNA topoisomerase III [Bacillus coagulans].	27.87	549	332	17	7	540	5	504	3e-46	183
tr:A0A0B0I044_9BACL	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:KHF34212.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHF34212.1};	28.23	620	381	22	5	590	3	592	3e-46	184
tr:D6E5U2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.47	612	372	17	7	553	6	604	3e-46	187
tr:R2B9H1_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.24	556	368	16	5	544	3	543	3e-46	183
rs:WP_044320067	DNA topoisomerase III [Pseudomonas amygdali].	26.70	588	387	15	7	565	4	576	3e-46	184
rs:WP_021948190	DNA topoisomerase III [Prevotella sp. CAG:1124].	28.26	545	339	17	7	531	2	514	3e-46	183
rs:WP_035817413	DNA topoisomerase III [Cupriavidus sp. SK-4].	28.97	573	351	19	7	550	6	551	3e-46	185
rs:WP_039421649	DNA topoisomerase III [Porphyromonas gulae].	27.04	540	349	18	7	531	2	511	3e-46	183
rs:WP_005348013	MULTISPECIES: DNA topoisomerase [Eubacterium].	27.71	599	388	18	7	582	5	581	3e-46	184
rs:WP_044422738	DNA topoisomerase III [Pseudomonas syringae group genomosp. 3].	26.40	591	391	15	4	565	1	576	3e-46	184
rs:WP_036899393	DNA topoisomerase III [Prevotella sp. S7 MS 2].	28.26	559	329	20	7	531	2	522	3e-46	183
rs:WP_039435848	DNA topoisomerase III [Porphyromonas gulae].	27.04	540	349	18	7	531	2	511	3e-46	183
rs:WP_046674940	DNA topoisomerase I [Sphingobacterium sp. Ag1].	28.44	559	338	17	4	531	1	528	3e-46	183
rs:WP_009962376	DNA topoisomerase III [Burkholderia pseudomallei].	27.99	561	369	15	7	550	6	548	3e-46	184
rs:WP_044923851	DNA topoisomerase III [Anaerostipes hadrus].	27.24	591	377	20	7	555	5	584	3e-46	183
rs:WP_018375466	DNA topoisomerase [Streptococcus orisratti].	29.03	558	338	19	4	547	2	515	3e-46	182
rs:WP_011374468	DNA topoisomerase III [Lactobacillus sakei].	28.70	561	326	20	7	550	6	509	3e-46	183
rs:WP_007884149	DNA topoisomerase III [Roseburia inulinivorans].	27.67	571	344	15	7	548	2	532	3e-46	183
rs:WP_026045275	DNA topoisomerase III [Burkholderia pyrrocinia].	28.16	561	368	15	7	550	6	548	3e-46	184
rs:WP_039730506	DNA topoisomerase, partial [Enterococcus mundtii].	29.42	486	317	12	72	544	1	473	3e-46	183
rs:WP_029642229	DNA topoisomerase III, partial [Acinetobacter baumannii].	32.88	368	221	7	194	537	10	375	3e-46	181
rs:WP_002340557	DNA topoisomerase III [Enterococcus faecium].	28.20	571	353	18	4	544	2	545	3e-46	183
rs:WP_002977772	DNA topoisomerase III [Chryseobacterium gleum].	30.09	545	326	20	8	531	5	515	3e-46	183
rs:WP_002578877	DNA topoisomerase III [[Clostridium] bolteae].	26.16	562	357	15	7	549	4	526	4e-46	183
rs:WP_007037046	DNA topoisomerase III [[Clostridium] bolteae].	27.67	571	344	15	7	548	4	534	4e-46	183
tr:X8IV48_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.77	504	289	16	7	491	4	456	4e-46	180
rs:WP_042371118	DNA topoisomerase III [Bacteroidaceae bacterium MS4].	27.31	542	344	15	7	531	2	510	4e-46	183
rs:WP_036796284	DNA topoisomerase III, partial [Photobacterium phosphoreum].	29.71	451	290	12	116	548	3	444	4e-46	181
rs:WP_003705193	DNA topoisomerase III [Lactobacillus salivarius].	28.93	560	325	20	7	550	5	507	4e-46	183
rs:WP_031944022	TraE conjugative transfer protein, DNA topoisomerase [uncultured bacterium pAKD4].	26.26	575	374	15	7	550	4	559	4e-46	183
rs:WP_026771463	DNA topoisomerase [Sediminibacillus halophilus].	26.77	609	398	20	7	590	4	589	4e-46	183
rs:WP_012742985	DNA topoisomerase [Eubacterium rectale].	26.19	611	375	16	7	553	6	604	4e-46	186
rs:WP_015063531	TraE Conjugative transfer protein, DNA topoisomerase [Burkholderia cepacia].	25.82	608	392	16	7	574	4	592	4e-46	183
rs:WP_010811329	DNA topoisomerase III [Ralstonia sp. GA3-3].	28.50	600	371	20	7	577	6	576	4e-46	184
rs:WP_034909951	DNA topoisomerase, partial [Peptostreptococcaceae bacterium OBRC8].	28.91	505	287	18	7	491	4	456	4e-46	180
rs:WP_034820457	DNA topoisomerase [[Eubacterium] nodatum].	29.23	544	328	19	7	539	4	501	4e-46	182
tr:N0DXA8_STRPY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.67	558	363	17	5	544	3	543	4e-46	183
rs:WP_045716702	DNA topoisomerase III, partial [Salmonella enterica].	29.17	432	284	12	8	428	5	425	4e-46	179
rs:WP_011171725	DNA topoisomerase III [Achromobacter denitrificans].	26.26	575	374	15	7	550	4	559	4e-46	183
rs:WP_036380219	DNA topoisomerase, partial [Mogibacterium timidum].	28.77	504	289	16	7	491	4	456	4e-46	179
rs:WP_029471079	DNA topoisomerase III [Clostridiales bacterium VE202-06].	27.98	554	338	16	7	539	4	517	4e-46	183
rs:WP_041228250	DNA topoisomerase III [Cupriavidus necator].	28.97	573	351	19	7	550	6	551	4e-46	184
rs:WP_035508200	MULTISPECIES: DNA topoisomerase III [Halobacillus].	28.27	566	349	19	7	544	5	541	4e-46	183
rs:WP_045121307	hypothetical protein, partial [Haliangium ochraceum].	25.00	624	410	15	1	580	1	610	4e-46	184
rs:WP_010759745	DNA topoisomerase III [Enterococcus pallens].	26.93	557	339	18	7	550	5	506	4e-46	183
tr:A0A0B7JB60_PHOPO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.71	451	290	12	116	548	15	456	4e-46	181
tr:J4WI89_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.91	505	287	18	7	491	4	456	4e-46	180
rs:WP_008653004	DNA topoisomerase I [Bacteroides sp. 3_1_33FAA].	28.92	574	346	20	4	552	1	537	4e-46	183
rs:WP_009491930	DNA topoisomerase III [Catellicoccus marimammalium].	28.73	536	317	17	7	532	5	485	4e-46	183
rs:WP_022277691	DNA topoisomerase III [Bacteroides coprophilus CAG:333].	27.67	571	339	20	7	531	2	544	4e-46	183
rs:WP_008143492	DNA topoisomerase III [Bacteroides coprophilus].	27.67	571	339	20	7	531	2	544	4e-46	183
rs:WP_004564283	DNA topoisomerase III [Lactobacillus salivarius].	29.29	560	323	21	7	550	5	507	4e-46	183
rs:WP_011616268	DNA topoisomerase III [Cupriavidus necator].	28.50	600	371	20	7	577	6	576	4e-46	184
rs:WP_004607961	DNA topoisomerase III [[Clostridium] scindens].	27.67	571	344	15	7	548	4	534	4e-46	183
rs:WP_045048228	DNA topoisomerase III, partial [Rouxiella chamberiensis].	30.42	378	238	9	170	531	63	431	4e-46	181
tr:B7U5A8_BACIU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.87	529	332	18	7	531	5	498	4e-46	183
rs:WP_044909883	DNA topoisomerase III [Lachnospiraceae bacterium MC2017].	28.09	559	338	17	7	539	4	524	4e-46	183
tr:D0LL88_HALO1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.00	624	410	15	1	580	1	610	4e-46	184
rs:WP_007486318	DNA topoisomerase I [Bacteroides nordii].	27.29	568	363	18	4	552	1	537	4e-46	183
rs:WP_039644438	DNA topoisomerase III [Staphylococcus hyicus].	26.46	567	371	15	7	559	5	539	4e-46	183
rs:WP_022978745	DNA topoisomerase III [Ideonella sp. B508-1].	28.97	604	370	23	3	567	2	585	4e-46	184
rs:WP_014680744	DNA topoisomerase III [Solitalea canadensis].	29.10	543	329	18	8	531	5	510	4e-46	183
tr:R6E059_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:CDA83657.1};	27.52	556	353	17	7	531	2	538	4e-46	183
rs:WP_017755419	hypothetical protein [Bacillus sp. ZYK].	26.64	608	381	20	4	579	1	575	4e-46	183
rs:WP_023249656	DNA topoisomerase III, partial [Salmonella enterica].	29.17	432	284	12	8	428	5	425	4e-46	179
rs:WP_028820891	DNA topoisomerase III [beta proteobacterium SCGC AAA027-I06].	27.96	608	373	19	5	568	3	589	4e-46	185
tr:W7YS18_9BACT	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:GAF05224.1};	28.44	524	335	16	8	521	5	498	4e-46	181
rs:WP_005933470	DNA topoisomerase III [Bacteroides salyersiae].	27.73	541	342	15	7	531	2	509	4e-46	183
rs:WP_025277526	DNA topoisomerase III [Barnesiella viscericola].	28.63	531	344	14	8	531	5	507	4e-46	183
rs:WP_031840280	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	30.10	392	253	9	172	548	2	387	5e-46	180
rs:WP_022219532	DNA topoisomerase III [Bacteroides clarus CAG:160].	27.39	566	349	21	7	531	2	546	5e-46	183
rs:WP_036297314	DNA topoisomerase [Methylobacter whittenburyi].	28.99	545	349	18	4	539	1	516	5e-46	183
tr:A0A0D8IXC4_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KJF39154.1};	26.29	563	355	15	7	549	4	526	5e-46	183
rs:WP_025271599	DNA topoisomerase [Streptococcus anginosus].	27.79	547	332	19	7	539	4	501	5e-46	181
rs:WP_029506177	DNA topoisomerase III, partial [Lachnospiraceae bacterium AC2012].	27.97	572	342	16	7	547	4	536	5e-46	182
tr:J9GKB8_9ZZZZ	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EJX00095.1};	28.01	557	349	18	7	531	2	538	5e-46	183
rs:WP_020315918	DNA topoisomerase III, partial [Pseudomonas syringae].	33.15	365	221	10	7	364	4	352	5e-46	177
rs:WP_040882743	DNA topoisomerase III [Johnsonella ignava].	27.45	561	349	16	7	550	2	521	5e-46	183
rs:WP_016268580	DNA topoisomerase III [Bacteroides thetaiotaomicron].	27.03	555	356	16	7	531	2	537	5e-46	183
rs:WP_008271599	DNA topoisomerase III [Flavobacteriales bacterium ALC-1].	28.09	534	345	16	8	531	5	509	5e-46	183
rs:WP_017553252	DNA topoisomerase III [Bacillus coagulans].	27.87	549	332	17	7	540	5	504	5e-46	183
rs:WP_003078034	toprim domain / DNA topoisomerase multi-domain protein [Streptococcus intermedius].	27.65	622	377	19	4	603	2	572	5e-46	182
rs:WP_005470120	MULTISPECIES: DNA topoisomerase III [Enterococcus].	27.61	612	370	21	7	603	5	558	5e-46	183
rs:WP_003128167	DNA topoisomerase III [Enterococcus gallinarum].	27.61	612	370	21	7	603	5	558	5e-46	183
rs:WP_017550807	DNA topoisomerase III [Bacillus coagulans].	27.69	549	333	17	7	540	5	504	5e-46	183
rs:WP_002351490	hypothetical protein [Streptococcus mutans].	27.87	628	366	24	4	602	2	571	5e-46	182
tr:B7ATA4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.81	623	369	19	5	553	8	617	5e-46	183
rs:WP_029046468	DNA topoisomerase III [Cupriavidus sp. amp6].	28.33	600	372	20	7	577	6	576	5e-46	184
rs:WP_022123622	DNA topoisomerase [Clostridium sp. CAG:510].	26.89	595	374	18	7	554	6	586	5e-46	186
rs:WP_029277927	DNA topoisomerase III [Pedobacter borealis].	28.80	566	341	18	7	543	4	536	5e-46	182
rs:WP_036247736	DNA topoisomerase III [Massilia sp. BSC265].	28.75	567	360	16	7	550	6	551	5e-46	184
tr:G5Q3L3_SALMO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.51	365	234	9	200	552	17	377	5e-46	180
rs:WP_046242841	DNA topoisomerase III [Hymenobacter sp. MIMtkLc17].	26.46	567	354	16	7	531	2	547	5e-46	184
rs:WP_020152122	hypothetical protein [Verrucomicrobia bacterium SCGC AAA300-N18].	30.05	549	338	18	7	531	5	531	5e-46	184
rs:WP_047097004	DNA topoisomerase III [Chryseobacterium indologenes].	30.09	545	326	20	8	531	5	515	5e-46	183
rs:WP_034697604	DNA topoisomerase III [Chryseobacterium sp. CF365].	29.54	545	329	20	8	531	5	515	5e-46	183
tr:D4LSE8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.62	601	369	22	8	554	7	595	5e-46	182
rs:WP_040893084	DNA topoisomerase III [[Bacteroides] pectinophilus].	26.81	623	369	19	5	553	4	613	5e-46	182
rs:WP_002576229	DNA topoisomerase III [[Clostridium] bolteae].	26.41	568	360	15	1	549	1	529	5e-46	182
tr:G5GJE6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.45	561	349	16	7	550	18	537	5e-46	183
rs:WP_013390829	DNA topoisomerase III [Achromobacter xylosoxidans].	28.82	576	353	18	5	550	4	552	6e-46	184
rs:WP_029453315	DNA topoisomerase III [Clostridium algidicarnis].	28.52	610	383	21	7	590	5	587	6e-46	182
rs:WP_038696442	DNA topoisomerase III [Paenibacillus stellifer].	26.98	630	389	21	5	599	3	596	6e-46	183
rs:WP_045670938	DNA topoisomerase III [Paenibacillus beijingensis].	27.84	643	362	25	7	604	5	590	6e-46	183
rs:WP_035463497	DNA topoisomerase III [Lactobacillus ceti].	26.93	557	340	18	7	550	6	508	6e-46	182
rs:WP_022510519	DNA topoisomerase [Prevotella sp. CAG:617].	28.04	560	354	19	8	550	5	532	6e-46	182
rs:WP_044954121	DNA topoisomerase III [Faecalibacterium prausnitzii].	27.13	575	347	19	7	550	4	537	6e-46	182
rs:WP_020157765	DNA topoisomerase [Methylobacter marinus].	29.42	537	341	18	4	531	1	508	6e-46	183
rs:WP_006843458	DNA topoisomerase III [Dysgonomonas mossii].	27.64	539	345	17	8	531	5	513	6e-46	182
rs:WP_039866065	DNA topoisomerase I, partial [Pedobacter sp. BAL39].	28.65	548	341	17	7	531	4	524	6e-46	182
rs:WP_035779841	DNA topoisomerase III [Butyrivibrio sp. MC2013].	28.15	572	341	16	7	547	4	536	6e-46	182
rs:WP_004563798	DNA topoisomerase III [Lactobacillus salivarius].	29.16	559	321	22	7	549	5	504	6e-46	182
rs:WP_002790206	DNA topoisomerase III, partial [Campylobacter coli].	26.20	584	378	16	8	559	5	567	6e-46	182
rs:WP_008979754	DNA topoisomerase III [Peptoclostridium difficile].	27.91	559	350	18	7	550	4	524	6e-46	182
rs:WP_022233792	DNA topoisomerase TopB [Bacteroides sp. CAG:443].	27.83	557	353	17	4	543	1	525	6e-46	182
rs:WP_046311290	DNA topoisomerase III [Pontibacter korlensis].	27.61	547	342	19	8	531	5	520	6e-46	183
rs:WP_009381486	DNA topoisomerase III [Megasphaera genomosp. type_1].	28.21	553	322	19	7	539	6	503	6e-46	181
rs:WP_025370374	hypothetical protein [Campylobacter fetus].	26.22	595	389	15	7	566	5	584	6e-46	183
rs:WP_007172766	DNA topoisomerase III [Prevotella bergensis].	26.99	552	346	15	7	531	2	523	6e-46	182
rs:WP_047034075	DNA topoisomerase I [Elizabethkingia meningoseptica].	28.15	572	353	18	4	552	1	537	6e-46	182
rs:WP_015389216	DNA topoisomerase III [Candidatus Kinetoplastibacterium galatii].	29.58	568	356	17	7	550	6	553	6e-46	183
rs:WP_045181198	DNA topoisomerase III [Elizabethkingia sp. BM10].	29.13	539	336	18	8	531	5	512	6e-46	182
rs:WP_007828684	DNA topoisomerase III [Variovorax sp. CF313].	28.16	618	364	25	5	568	4	595	6e-46	185
rs:WP_020566248	DNA topoisomerase III [Burkholderia sp. JPY347].	28.16	561	368	16	7	550	6	548	6e-46	184
rs:WP_003510888	DNA topoisomerase III [[Clostridium] symbiosum].	26.64	563	352	19	7	550	4	524	6e-46	182
rs:WP_039959342	DNA topoisomerase III [[Ruminococcus] gnavus].	26.01	569	361	14	1	549	1	529	6e-46	182
rs:WP_025577806	DNA topoisomerase III [Blautia wexlerae].	27.56	566	346	15	7	550	6	529	6e-46	182
rs:WP_009123155	DNA topoisomerase III [Bacteroides clarus].	27.39	566	349	21	7	531	2	546	6e-46	182
tr:A7AZM6_RUMGN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.01	569	361	14	1	549	3	531	6e-46	182
rs:WP_008759804	DNA topoisomerase III [Bacteroides sp. 1_1_14].	26.77	564	346	18	7	531	2	537	6e-46	182
rs:WP_036057673	hypothetical protein, partial [Burkholderia mallei].	28.88	561	347	19	5	544	3	532	6e-46	181
rs:WP_031538172	DNA topoisomerase [Bacillus sp. MB2021].	27.60	605	395	17	7	590	4	586	6e-46	182
rs:WP_015602408	DNA topoisomerase III family protein [Burkholderia thailandensis].	27.99	561	369	15	7	550	6	548	6e-46	184
rs:WP_009291857	DNA topoisomerase I [Bacteroides sp. 2_1_56FAA].	28.75	574	347	20	4	552	1	537	6e-46	182
rs:WP_009249981	DNA topoisomerase III [Lachnospiraceae bacterium 3_1_57FAA_CT1].	28.34	554	336	17	7	539	4	517	6e-46	182
rs:WP_012679621	DNA topoisomerase III [Streptococcus equi].	27.94	544	339	16	5	539	3	502	7e-46	181
rs:WP_013978336	DNA topoisomerase III [Clostridium sp. SY8519].	27.71	599	364	21	8	554	7	588	7e-46	182
rs:WP_007870325	DNA topoisomerase III [Polaromonas sp. CF318].	28.03	603	377	18	5	568	3	587	7e-46	184
rs:WP_034474891	DNA topoisomerase [Butyrivibrio proteoclasticus].	27.75	591	360	20	7	544	6	582	7e-46	185
rs:WP_002584963	MULTISPECIES: DNA topoisomerase III [Clostridiales].	25.99	558	362	16	7	550	4	524	7e-46	182
rs:WP_007851815	MULTISPECIES: DNA topoisomerase I [Bacteroides].	27.11	568	364	18	4	552	1	537	7e-46	182
rs:WP_046977534	conjugal transfer protein TraE [Xanthomonas hyacinthi].	26.09	575	375	15	7	550	4	559	7e-46	182
rs:WP_033143528	DNA topoisomerase III [Blautia producta].	27.96	558	333	19	7	539	4	517	7e-46	182
rs:WP_011299539	DNA topoisomerase III [Cupriavidus pinatubonensis].	28.33	600	372	20	7	577	6	576	7e-46	184
rs:WP_039139562	DNA topoisomerase III, partial [Gallibacterium anatis].	32.51	363	214	12	210	548	6	361	7e-46	179
rs:WP_023263469	DNA topoisomerase III [Cupriavidus sp. HPC(L)].	27.62	601	373	21	7	577	6	574	7e-46	184
rs:WP_014098426	DNA topoisomerase III [Bacillus coagulans].	28.02	546	335	18	7	540	5	504	7e-46	182
rs:WP_036039160	DNA topoisomerase III [Burkholderia gladioli].	27.63	561	371	15	7	550	6	548	7e-46	184
gpu:CP009928_37	DNA topoisomerase III [Chryseobacterium gallinarum]	29.72	545	328	20	8	531	5	515	7e-46	182
rs:WP_016219336	DNA topoisomerase III [Dorea sp. 5-2].	28.08	552	340	16	7	539	4	517	7e-46	182
rs:WP_044314482	DNA topoisomerase III, partial [Pseudomonas stutzeri].	33.14	338	211	8	8	342	5	330	7e-46	176
rs:WP_029731804	DNA topoisomerase III [Dorea sp. AGR2135].	28.11	555	336	18	7	539	4	517	7e-46	182
rs:WP_042233258	DNA topoisomerase III, partial [Paenibacillus chitinolyticus].	26.89	621	388	19	5	590	3	592	7e-46	182
rs:WP_002261844	hypothetical protein [Streptococcus mutans].	29.00	562	333	20	4	547	2	515	7e-46	181
rs:WP_009218765	DNA topoisomerase III [Lachnospiraceae oral taxon 107].	28.57	553	320	19	7	539	4	501	7e-46	181
tr:D8L9Y3_CAMFE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:CBH51817.1};	26.26	594	389	16	7	566	5	583	7e-46	182
rs:WP_032854695	DNA topoisomerase I [Bacteroides ovatus].	27.11	568	364	18	4	552	1	537	7e-46	182
rs:WP_025154735	hypothetical protein [Morganella morganii].	27.39	566	364	13	8	543	5	553	7e-46	182
rs:WP_036623080	DNA topoisomerase III [Paenibacillus macerans].	28.60	563	346	19	5	540	3	536	7e-46	182
rs:WP_031533880	MULTISPECIES: DNA topoisomerase III [Bacteroides].	28.07	545	341	17	7	531	2	515	7e-46	182
rs:WP_004371446	DNA topoisomerase III [Prevotella oris].	28.40	574	331	20	7	531	2	544	7e-46	182
tr:E6J286_STRAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.29	502	311	14	47	539	1	462	7e-46	180
rs:WP_033612972	DNA topoisomerase, partial [Enterococcus faecium].	28.42	556	367	16	5	544	3	543	7e-46	182
rs:WP_021824609	DNA topoisomerase III [Prevotella salivae].	28.52	575	329	20	7	531	2	544	7e-46	182
rs:WP_021974742	DNA topoisomerase [Firmicutes bacterium CAG:884].	30.24	572	341	22	7	556	4	539	7e-46	182
rs:WP_043192735	DNA topoisomerase III, partial [Burkholderia glumae].	27.81	561	370	15	7	550	6	548	7e-46	183
rs:WP_032854693	MULTISPECIES: DNA topoisomerase I [Bacteroides].	27.11	568	364	18	4	552	1	537	7e-46	182
rs:WP_031543238	DNA topoisomerase III, partial [Lachnospiraceae bacterium AC2014].	27.80	572	343	16	7	547	4	536	7e-46	182
tr:A0A086F9L8_9FLAO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KFF75632.1};	29.72	545	328	20	8	531	5	515	7e-46	182
rs:WP_026683480	DNA topoisomerase III [Bacillus coagulans].	27.84	546	336	17	7	540	5	504	7e-46	182
rs:WP_020916758	DNA topoisomerase III [Streptococcus lutetiensis].	26.64	563	357	16	4	552	2	522	7e-46	181
rs:WP_002592896	DNA topoisomerase III [[Clostridium] clostridioforme].	26.32	570	358	15	1	549	1	529	8e-46	182
rs:WP_004326100	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.67	579	341	20	4	552	1	537	8e-46	182
rs:WP_007516585	DNA topoisomerase III [Streptococcus tigurinus].	28.21	553	322	19	7	539	4	501	8e-46	181
rs:WP_025571064	DNA topoisomerase III, partial [Flavobacterium sp. JGI 0001001-D01].	29.41	493	314	14	65	550	7	472	8e-46	182
rs:WP_004270975	DNA topoisomerase III [Lactobacillus curvatus].	28.98	559	328	19	7	550	6	510	8e-46	182
rs:WP_038748593	DNA topoisomerase III [Burkholderia pseudomallei].	27.81	561	370	15	7	550	6	548	8e-46	183
rs:WP_032535951	DNA topoisomerase I [Bacteroides fragilis].	28.92	574	346	20	4	552	1	537	8e-46	182
rs:WP_004832505	DNA topoisomerase [Parvimonas micra].	28.62	545	314	18	7	531	4	493	8e-46	181
rs:WP_034549249	DNA topoisomerase III [Clostridiales bacterium VE202-09].	26.15	589	381	20	8	554	12	588	8e-46	182
rs:WP_007134283	DNA topoisomerase III [Prevotella salivae].	28.52	575	329	20	7	531	2	544	8e-46	182
tr:H5SNX8_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.57	584	377	20	7	567	13	573	8e-46	183
rs:WP_045469078	DNA topoisomerase III [Burkholderiales bacterium GJ-E10].	27.24	536	352	16	34	557	28	537	8e-46	182
rs:WP_046575281	DNA topoisomerase III [Burkholderia gladioli].	27.12	579	387	15	7	568	6	566	8e-46	184
rs:WP_044478705	DNA topoisomerase III, partial [Peptoclostridium difficile].	28.02	546	331	14	7	530	4	509	8e-46	180
rs:WP_032459628	DNA topoisomerase III [Streptococcus agalactiae].	28.16	554	321	20	7	539	6	503	8e-46	181
rs:WP_016174178	DNA topoisomerase III [Enterococcus saccharolyticus].	28.04	560	330	21	7	550	5	507	8e-46	182
rs:WP_016911088	hypothetical protein [Staphylococcus vitulinus].	26.03	584	353	18	7	559	5	540	8e-46	182
tr:A6E8D3_9SPHI	SubName: Full=Putative transposon excision protein {ECO:0000313|EMBL:EDM38263.1};	28.47	548	342	17	7	531	4	524	8e-46	182
rs:WP_039099504	DNA topoisomerase III [Lactobacillus curvatus].	28.47	555	336	18	7	550	6	510	8e-46	182
rs:WP_028555965	DNA topoisomerase III [Paenibacillus sp. URHA0014].	27.07	639	393	23	5	601	3	610	8e-46	182
rs:WP_036887964	DNA topoisomerase I [Prevotella bivia].	27.95	551	335	16	5	531	3	515	8e-46	182
rs:WP_009520786	DNA topoisomerase III [Ralstonia sp. PBA].	28.38	599	370	21	7	577	6	573	8e-46	183
rs:WP_033910164	conjugal transfer protein TraE [Neisseria gonorrhoeae].	26.71	569	374	15	8	548	6	559	8e-46	182
rs:WP_019924412	DNA topoisomerase III [Duganella zoogloeoides].	28.99	576	360	18	3	550	2	556	8e-46	184
rs:WP_014749157	DNA topoisomerase III [Advenella kashmirensis].	29.75	558	336	19	5	531	4	536	8e-46	184
rs:WP_032842963	DNA topoisomerase I [Bacteroides ovatus].	27.11	568	364	18	4	552	1	537	8e-46	182
rs:WP_040287707	DNA topoisomerase III [Sporosarcina koreensis].	28.24	556	360	17	7	544	5	539	8e-46	182
rs:WP_020505068	hypothetical protein [Lamprocystis purpurea].	27.46	568	353	16	5	539	3	544	8e-46	183
rs:WP_026350873	DNA topoisomerase III [Dyadobacter beijingensis].	28.73	543	331	18	8	531	5	510	9e-46	182
rs:WP_034866021	DNA topoisomerase III [Elizabethkingia miricola].	28.84	541	335	18	8	531	5	512	9e-46	182
rs:WP_034847279	DNA topoisomerase III [Elizabethkingia meningoseptica].	28.65	541	336	18	8	531	5	512	9e-46	182
rs:WP_040212160	DNA topoisomerase [Clostridium sp. MS1].	28.18	628	400	20	3	601	2	607	9e-46	182
rs:WP_013702783	DNA topoisomerase [Treponema succinifaciens].	29.39	558	336	20	7	540	3	526	9e-46	181
rs:WP_009672854	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	27.05	621	387	19	5	590	3	592	9e-46	182
rs:WP_036048796	MULTISPECIES: DNA topoisomerase III [Burkholderia].	27.12	579	387	15	7	568	6	566	9e-46	183
rs:WP_044013492	hypothetical protein [Treponema sp. OMZ 838].	29.26	557	341	20	4	539	1	525	9e-46	182
rs:WP_009003369	DNA topoisomerase III [Clostridium sp. D5].	26.58	568	359	15	1	549	1	529	9e-46	182
rs:WP_016362617	DNA topoisomerase III [Paenibacillus mucilaginosus].	27.29	623	385	18	5	590	3	594	9e-46	184
rs:WP_025097237	DNA topoisomerase III [Burkholderia sp. A1].	27.63	561	371	15	7	550	6	548	9e-46	183
rs:WP_024962447	DNA topoisomerase III [Campylobacter ureolyticus].	26.06	587	380	16	7	563	4	566	9e-46	182
tr:A0A0A1H8R7_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.24	536	352	16	34	557	30	539	9e-46	182
rs:WP_045474264	DNA topoisomerase III [Winogradskyella sp. PG-2].	27.69	549	360	16	8	550	5	522	9e-46	182
rs:WP_036248694	DNA topoisomerase [Methylobacter sp. BBA5.1].	29.24	537	342	18	4	531	1	508	9e-46	182
rs:WP_024535808	DNA topoisomerase III [Sporosarcina sp. EUR3 2.2.2].	28.29	555	360	16	7	544	5	538	9e-46	182
tr:R1K8N3_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.24	556	368	16	5	544	3	543	9e-46	182
rs:WP_013699754	DNA topoisomerase III [Burkholderia gladioli].	27.12	579	387	15	7	568	6	566	9e-46	183
rs:WP_027380549	DNA topoisomerase III [Chryseobacterium daeguense].	29.91	545	327	21	8	531	5	515	9e-46	182
rs:WP_009125918	DNA topoisomerase I [Bacteroides fluxus].	27.11	568	364	18	4	552	1	537	9e-46	182
tr:A0A099Y2H8_9FLAO	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.75	557	342	17	8	531	5	528	9e-46	182
rs:WP_022471349	DNA topoisomerase III [Bacteroides thetaiotaomicron CAG:40].	26.67	555	358	16	7	531	2	537	1e-45	182
rs:WP_035185010	DNA topoisomerase III [Bacillus coagulans].	27.69	549	333	17	7	540	5	504	1e-45	182
rs:WP_043935294	MULTISPECIES: hypothetical protein [Bacillus].	26.07	537	334	13	23	532	7	507	1e-45	182
tr:A0A0D0S6Q2_9FIRM	SubName: Full=TWA4_scaffold00001, whole genome shotgun sequence {ECO:0000313|EMBL:KIR01912.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIR01912.1};	28.77	584	338	22	38	568	10	568	1e-45	181
rs:WP_008766576	DNA topoisomerase III [Bacteroides sp. 1_1_6].	26.67	555	358	16	7	531	2	537	1e-45	182
rs:WP_025809633	DNA topoisomerase III [Bacillus licheniformis].	29.04	575	354	22	7	563	5	543	1e-45	182
rs:WP_017867276	DNA topoisomerase III [Lactobacillus pobuzihii].	27.98	554	338	19	7	550	5	507	1e-45	182
rs:WP_045754349	DNA topoisomerase I [Sphingobacterium sp. PM2-P1-29].	28.17	568	358	19	4	552	1	537	1e-45	182
rs:WP_022100017	DNA topoisomerase [Proteobacteria bacterium CAG:139].	28.18	582	379	19	5	567	4	565	1e-45	183
rs:WP_017921309	DNA topoisomerase III [Burkholderia gladioli].	27.12	579	387	15	7	568	6	566	1e-45	183
rs:WP_011108131	DNA topoisomerase III [Bacteroides thetaiotaomicron].	27.03	555	356	16	7	531	2	537	1e-45	182
rs:WP_027815887	DNA topoisomerase III [Burkholderia bannensis].	27.96	583	377	17	7	568	6	566	1e-45	183
rs:WP_006024093	DNA topoisomerase III [Burkholderia thailandensis].	27.99	561	369	15	7	550	6	548	1e-45	183
rs:WP_027973723	DNA topoisomerase [Streptococcus porci].	29.03	558	338	19	4	547	2	515	1e-45	181
rs:WP_044230524	DNA topoisomerase I [Coprobacter sp. 177].	28.55	578	342	21	4	552	1	536	1e-45	182
rs:WP_022463020	DNA topoisomerase III [Blautia sp. CAG:37].	27.39	595	371	19	8	553	7	589	1e-45	182
rs:WP_044322571	DNA topoisomerase III, partial [Pseudomonas amygdali].	26.57	591	390	15	4	565	1	576	1e-45	181
tr:D7IPC2_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFI09260.1};	27.44	532	339	17	15	531	2	501	1e-45	182
rs:WP_024566950	DNA topoisomerase III [Elizabethkingia anophelis].	28.65	541	336	18	8	531	5	512	1e-45	182
rs:WP_029141630	DNA topoisomerase III [Bacillus coagulans].	27.71	545	338	15	7	540	5	504	1e-45	182
rs:WP_020999844	DNA topoisomerase III [Streptococcus anginosus].	27.49	542	340	17	7	539	4	501	1e-45	181
tr:F3QYD9_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EGG50486.1};	27.66	564	347	17	7	531	35	576	1e-45	182
rs:WP_009092056	DNA topoisomerase III [Elizabethkingia anophelis].	28.65	541	336	18	8	531	5	512	1e-45	182
rs:WP_041734236	DNA topoisomerase III [Burkholderia sp. CCGE1002].	27.24	580	385	16	7	568	6	566	1e-45	183
rs:WP_046447476	DNA topoisomerase III [Acinetobacter sp. N54.MGS-139].	28.18	582	379	19	5	567	4	565	1e-45	182
rs:WP_020485826	hypothetical protein [Methylomonas sp. MK1].	25.62	566	377	15	7	544	4	553	1e-45	182
rs:WP_042206965	DNA topoisomerase III [Paenibacillus durus].	27.19	629	389	20	5	599	3	596	1e-45	182
rs:WP_043902450	DNA topoisomerase, partial [Enterococcus faecium].	28.42	556	367	16	5	544	3	543	1e-45	181
rs:WP_012219851	DNA topoisomerase III [Vibrio sp. 23023].	29.17	552	356	14	4	532	1	540	1e-45	182
rs:WP_022319653	DNA topoisomerase [Dorea sp. CAG:317].	27.62	601	380	18	8	570	7	590	1e-45	181
rs:WP_007764104	DNA topoisomerase I [Bacteroides finegoldii].	26.82	604	394	18	4	591	1	572	1e-45	181
rs:WP_022823336	DNA topoisomerase III [Hymenobacter norwichensis].	26.12	582	373	17	4	550	1	560	1e-45	183
rs:WP_026320152	DNA topoisomerase III [Bacteroides barnesiae].	27.74	566	341	19	7	531	2	540	1e-45	182
rs:WP_022091462	DNA topoisomerase III [Lachnospiraceae bacterium CAG:25].	27.42	598	367	21	7	555	5	584	1e-45	181
rs:WP_033700641	DNA topoisomerase, partial [Enterococcus faecium].	28.42	556	367	16	5	544	3	543	1e-45	181
rs:WP_044271662	DNA topoisomerase III [Candidatus Bacteroides timonensis].	27.39	566	349	20	7	531	2	546	1e-45	182
rs:WP_018697076	DNA topoisomerase I [Alistipes onderdonkii].	27.11	568	364	18	4	552	1	537	1e-45	182
rs:WP_007124650	DNA topoisomerase, partial [Lactobacillus antri].	27.59	580	378	16	43	603	1	557	1e-45	181
rs:WP_016121292	DNA topoisomerase III [Bacillus cereus].	29.71	589	344	19	6	556	5	561	1e-45	182
rs:WP_031644658	DNA topoisomerase [Listeria monocytogenes].	28.42	556	367	16	5	544	3	543	1e-45	182
rs:WP_036823047	DNA topoisomerase III, partial [Polaribacter sp. Hel1_85].	26.75	557	342	17	8	531	5	528	1e-45	182
tr:W6UCE3_9SPHI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.11	553	332	20	7	531	4	524	1e-45	181
rs:WP_018436954	DNA topoisomerase III [Burkholderia sp. JPY251].	27.24	580	385	16	7	568	6	566	1e-45	183
rs:WP_023934205	DNA topoisomerase [Photobacterium leiognathi].	28.11	555	351	15	7	532	4	539	1e-45	182
rs:WP_013685590	DNA topoisomerase III [Fluviicola taffensis].	27.71	545	338	17	8	531	5	514	1e-45	182
rs:WP_024467148	hypothetical protein [Treponema pedis].	28.93	553	350	19	7	543	4	529	1e-45	180
tr:G9YLU1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.15	508	314	14	1	491	1	474	1e-45	179
rs:WP_014620285	DNA topoisomerase III [Streptococcus gallolyticus].	27.27	550	344	17	4	539	2	509	1e-45	181
rs:WP_025585606	DNA topoisomerase III [Cupriavidus taiwanensis].	27.95	601	373	20	7	577	6	576	1e-45	183
tr:D5W9E3_BURSC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.24	580	385	16	7	568	23	583	1e-45	183
rs:WP_004291456	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	26.82	604	394	18	4	591	1	572	1e-45	181
rs:WP_027799096	DNA topoisomerase III [Burkholderia dilworthii].	28.11	562	367	17	7	550	6	548	1e-45	183
rs:WP_040603203	DNA topoisomerase III [Paraprevotella xylaniphila].	27.66	564	347	17	7	531	2	543	1e-45	182
rs:WP_003710611	DNA topoisomerase III [Lactobacillus salivarius].	28.93	560	325	20	7	550	5	507	1e-45	181
rs:WP_021661456	DNA topoisomerase [Clostridium sp. ATCC 29733].	26.64	563	352	19	7	550	4	524	1e-45	181
rs:WP_038352446	hypothetical protein, partial [Eubacterium limosum].	27.87	610	387	22	7	590	5	587	1e-45	181
rs:WP_042228689	DNA topoisomerase III [Paenibacillus chitinolyticus].	26.60	579	345	19	3	550	2	531	1e-45	182
rs:WP_031580844	DNA topoisomerase III [Lachnospiraceae bacterium AC2028].	26.43	681	398	24	8	603	7	669	1e-45	181
rs:WP_047033420	DNA topoisomerase III [Elizabethkingia meningoseptica].	28.86	537	340	17	8	531	5	512	1e-45	181
rs:WP_002326769	DNA topoisomerase III, partial [Enterococcus faecium].	28.42	556	367	16	5	544	3	543	1e-45	181
rs:WP_025143486	DNA topoisomerase III [Sphingobacterium sp. H1ai].	28.27	566	344	18	7	543	4	536	1e-45	181
rs:WP_041505349	DNA topoisomerase I [Sanguibacteroides justesenii].	27.97	572	354	17	4	552	1	537	1e-45	181
rs:WP_015547215	DNA topoisomerase III, bacteria and conjugative plasmid [Alistipes shahii].	27.11	568	364	18	4	552	1	537	1e-45	181
rs:WP_022272651	DNA topoisomerase III [Clostridium sp. CAG:58].	26.59	613	369	23	7	550	6	606	1e-45	181
tr:Q3II03_PSEHT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.82	387	240	10	155	531	8	384	1e-45	179
rs:WP_007651964	DNA topoisomerase III [Pontibacter sp. BAB1700].	27.47	546	342	17	8	531	5	518	1e-45	182
rs:WP_026191728	DNA topoisomerase III [Methylosinus sp. LW4].	27.00	611	386	16	5	584	3	584	1e-45	181
rs:WP_032459429	DNA topoisomerase [Streptococcus agalactiae].	28.03	553	323	19	7	539	6	503	1e-45	180
rs:WP_045221390	hypothetical protein, partial [Desulfonatronum thioautotrophicum].	27.54	501	340	11	7	498	5	491	1e-45	181
rs:WP_044655159	DNA topoisomerase III [Bacteroides acidifaciens].	27.52	556	353	17	7	531	2	538	1e-45	181
rs:WP_032558157	MULTISPECIES: DNA topoisomerase I [Bacteroides].	27.11	568	364	18	4	552	1	537	1e-45	181
rs:WP_031786070	DNA topoisomerase III, partial [Staphylococcus aureus].	30.47	512	325	15	43	544	4	494	1e-45	181
rs:WP_020979454	DNA topoisomerase III [Burkholderia cenocepacia].	27.99	561	369	15	7	550	6	548	1e-45	182
rs:WP_011202386	DNA topoisomerase I [Bacteroides fragilis].	28.75	574	347	20	4	552	1	537	1e-45	181
tr:K1V4F0_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78771.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EKC78771.1};	28.29	555	335	17	7	539	4	517	1e-45	181
rs:WP_027213817	DNA topoisomerase III [Burkholderia sp. WSM2232].	28.29	562	366	17	7	550	6	548	1e-45	183
rs:WP_000463492	DNA topoisomerase III, partial [Salmonella enterica].	32.88	368	221	7	194	537	10	375	1e-45	180
rs:WP_007660662	DNA topoisomerase I [Bacteroides intestinalis].	26.82	604	394	18	4	591	1	572	1e-45	181
rs:WP_021346323	DNA topoisomerase III [Elizabethkingia meningoseptica].	28.65	541	336	18	8	531	5	512	1e-45	181
rs:WP_045930539	DNA topoisomerase III [Alcaligenes faecalis].	28.18	589	372	18	5	566	4	568	1e-45	182
tr:D4M0W5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.23	568	361	15	1	549	1	529	2e-45	181
rs:WP_027117982	DNA topoisomerase III [Lachnospiraceae bacterium YSB2008].	26.76	624	369	20	7	554	5	616	2e-45	181
rs:WP_029486302	DNA topoisomerase III [Enterococcus gallinarum].	27.45	612	371	21	7	603	5	558	2e-45	181
rs:WP_024733189	DNA topoisomerase III [Clostridiales bacterium VE202-14].	26.86	618	389	18	7	603	4	579	2e-45	181
rs:WP_044956898	DNA topoisomerase III [Butyrivibrio sp. LC3010].	26.73	550	345	17	7	539	5	513	2e-45	181
rs:WP_005213949	DNA topoisomerase [Clostridium celatum].	27.46	619	385	19	7	590	5	594	2e-45	181
rs:WP_003600531	DNA topoisomerase III, partial [Lactobacillus casei].	29.02	541	346	18	43	563	1	523	2e-45	181
rs:WP_026769694	DNA topoisomerase I [Sediminibacterium sp. OR53].	28.60	556	330	19	4	531	1	517	2e-45	181
rs:WP_006947859	DNA topoisomerase III [Prevotella marshii].	27.97	547	338	18	7	531	2	514	2e-45	181
rs:WP_047068304	DNA topoisomerase III [Brevibacillus formosus].	27.39	639	379	23	7	599	5	604	2e-45	181
rs:WP_021967732	MULTISPECIES: DNA topoisomerase III [Bacteroides].	27.26	565	351	19	7	531	2	546	2e-45	181
rs:WP_005812009	DNA topoisomerase I [Bacteroides fragilis].	26.82	604	394	18	4	591	1	572	2e-45	181
rs:WP_033918726	DNA topoisomerase, partial [Enterococcus faecalis].	28.60	556	366	17	5	544	3	543	2e-45	180
tr:U3N979_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.57	504	308	15	7	491	4	474	2e-45	179
rs:WP_009203366	DNA topoisomerase III [Anaerostipes hadrus].	27.12	590	377	20	8	555	6	584	2e-45	181
rs:WP_002594792	DNA topoisomerase III [[Clostridium] clostridioforme].	26.47	563	356	17	7	550	6	529	2e-45	181
rs:WP_007594042	DNA topoisomerase III [Lachnoanaerobaculum sp. OBRC5-5].	28.08	609	371	25	7	601	4	559	2e-45	180
rs:WP_007659952	DNA topoisomerase III [Bacteroides intestinalis].	27.26	565	351	19	7	531	2	546	2e-45	181
rs:WP_034684347	DNA topoisomerase III [Enterococcus phoeniculicola].	27.36	552	340	17	7	548	5	505	2e-45	181
rs:WP_039476110	DNA topoisomerase III [Pectobacterium carotovorum].	27.39	566	371	13	7	543	4	558	2e-45	182
rs:WP_002595835	DNA topoisomerase III [[Clostridium] clostridioforme].	26.32	570	358	15	1	549	1	529	2e-45	181
rs:WP_021980997	DNA topoisomerase III [Paraprevotella clara CAG:116].	27.13	564	350	17	7	531	2	543	2e-45	181
rs:WP_008664059	DNA topoisomerase III [Bacteroides sp. 4_1_36].	27.21	566	351	18	7	531	2	547	2e-45	181
rs:WP_005681364	MULTISPECIES: DNA topoisomerase I [Bacteroides].	27.11	568	364	18	4	552	1	537	2e-45	181
rs:WP_008751237	DNA topoisomerase III [Lachnoanaerobaculum saburreum].	26.58	647	380	25	8	590	6	621	2e-45	181
rs:WP_002351810	DNA topoisomerase III, partial [Enterococcus faecium].	28.42	556	367	17	5	544	3	543	2e-45	181
rs:WP_003800563	DNA topoisomerase III [Alcaligenes faecalis].	28.18	589	372	18	5	566	4	568	2e-45	182
rs:WP_026483868	DNA topoisomerase III [Alcaligenes faecalis].	28.18	589	372	18	5	566	4	568	2e-45	182
rs:WP_038142129	DNA topoisomerase III, partial [Verrucomicrobia bacterium SCGC AAA164-E04].	29.24	578	343	22	7	550	6	551	2e-45	182
rs:WP_004322053	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	28.35	568	349	18	4	550	1	531	2e-45	181
rs:WP_035269284	DNA topoisomerase III [Alcaligenes faecalis].	28.18	589	372	18	5	566	4	568	2e-45	182
rs:WP_009090442	DNA topoisomerase [Elizabethkingia anophelis].	28.35	575	332	18	4	550	1	523	2e-45	181
rs:WP_037622473	DNA topoisomerase [Streptococcus sp. 2_1_36FAA].	27.59	569	344	18	4	552	2	522	2e-45	180
rs:WP_000108743	MULTISPECIES: DNA topoisomerase [Bacilli].	28.42	556	367	16	5	544	3	543	2e-45	181
rs:WP_008391044	DNA topoisomerase III [Clostridium sp. SS2/1].	27.24	591	377	21	7	555	5	584	2e-45	181
rs:WP_028221532	DNA topoisomerase III [Burkholderia oxyphila].	27.46	579	385	15	7	568	6	566	2e-45	182
rs:WP_044467849	DNA topoisomerase III [Bacteroides uniformis].	27.21	566	351	18	7	531	2	547	2e-45	181
rs:WP_043210668	DNA topoisomerase III [Bordetella hinzii].	29.37	572	355	19	5	550	4	552	2e-45	182
rs:WP_013634106	DNA topoisomerase III [Pedobacter saltans].	28.09	566	352	17	4	543	1	537	2e-45	180
rs:WP_007045777	DNA topoisomerase III [Subdoligranulum variabile].	26.97	571	353	17	1	549	1	529	2e-45	181
rs:WP_022495166	DNA topoisomerase [Ruminococcus sp. CAG:624].	27.32	615	401	19	7	604	4	589	2e-45	181
tr:G9X0K0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.64	496	295	18	7	491	4	456	2e-45	178
rs:WP_015535784	DNA topoisomerase III, bacteria and conjugative plasmid [Faecalitalea cylindroides].	26.63	567	348	15	7	549	4	526	2e-45	181
rs:WP_038327617	DNA topoisomerase III, partial [beta proteobacterium SCGC AAA027-K21].	28.96	556	347	17	5	534	4	537	2e-45	182
rs:WP_044005117	DNA topoisomerase III [Lactobacillus salivarius].	28.93	560	325	20	7	550	5	507	2e-45	181
rs:WP_004357490	DNA topoisomerase III [Prevotella disiens].	28.70	554	336	20	8	531	5	529	2e-45	180
rs:WP_046797616	conjugal transfer protein TraE [Rhizobium sp. LC145].	26.56	576	367	17	7	548	7	560	2e-45	181
rs:WP_018711724	DNA topoisomerase I [Bacteroides barnesiae].	26.82	604	394	18	4	591	1	572	2e-45	181
rs:WP_012020800	DNA topoisomerase [Metallosphaera sedula].	27.82	550	328	18	7	548	4	492	2e-45	181
rs:WP_005924167	DNA topoisomerase III [Bacteroides salyersiae].	28.75	574	347	20	4	552	1	537	2e-45	181
rs:WP_044225363	DNA topoisomerase III [Coprobacter sp. 177].	28.57	546	333	21	8	531	5	515	2e-45	181
rs:WP_008620900	DNA topoisomerase I [Paraprevotella clara].	28.75	574	347	20	4	552	1	537	2e-45	181
rs:WP_000108741	MULTISPECIES: DNA topoisomerase [Bacilli].	28.06	556	369	16	5	544	3	543	2e-45	181
rs:WP_022173204	DNA topoisomerase [Blautia sp. CAG:52].	27.54	621	364	22	5	553	4	610	2e-45	181
rs:WP_029657514	DNA topoisomerase III, partial [Staphylococcus aureus].	30.47	512	325	15	43	544	14	504	2e-45	181
rs:WP_033892104	DNA topoisomerase III [Bifidobacterium saguini].	27.58	562	350	17	7	539	4	537	2e-45	181
rs:WP_036881990	DNA topoisomerase III [Prevotella disiens].	28.34	554	338	19	8	531	5	529	2e-45	180
rs:WP_025064416	DNA topoisomerase III [Prevotella disiens].	28.70	554	336	20	8	531	5	529	2e-45	180
rs:WP_022537063	DNA topoisomerase III [Ralstonia pickettii].	28.12	601	372	20	7	577	6	576	2e-45	182
rs:WP_029232734	DNA topoisomerase [Butyrivibrio sp. VCB2006].	28.40	581	353	20	7	536	6	574	2e-45	184
rs:WP_018666382	DNA topoisomerase III [Bacteroides gallinarum].	26.90	565	353	18	7	531	2	546	2e-45	181
rs:WP_031835761	DNA topoisomerase III, partial [Staphylococcus aureus].	30.47	512	325	15	43	544	8	498	2e-45	181
rs:WP_018005000	DNA topoisomerase III [Cupriavidus taiwanensis].	28.00	600	374	20	7	577	6	576	2e-45	182
rs:WP_044545931	DNA topoisomerase I, partial [Parabacteroides distasonis].	28.57	574	348	20	4	552	1	537	2e-45	180
rs:WP_022010842	DNA topoisomerase III [Firmicutes bacterium CAG:646].	26.90	606	376	19	3	553	2	595	2e-45	181
rs:WP_012354342	DNA topoisomerase III [Cupriavidus taiwanensis].	27.95	601	373	20	7	577	6	576	2e-45	182
rs:WP_036210415	DNA topoisomerase III [Massilia sp. LC238].	28.40	567	362	16	7	550	6	551	2e-45	182
rs:WP_013438841	topoisomerase [Enterococcus faecalis].	28.42	556	367	16	5	544	3	543	2e-45	181
rs:WP_009893647	DNA topoisomerase III [Burkholderia thailandensis].	27.81	561	370	15	7	550	6	548	2e-45	182
rs:WP_028357446	DNA topoisomerase III [Brackiella oedipodis].	29.44	574	338	22	3	534	2	550	2e-45	182
rs:WP_004666758	DNA topoisomerase III [Pseudomonas savastanoi].	26.17	554	357	15	35	546	33	576	2e-45	182
tr:D0RWS4_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.59	569	344	18	4	552	43	563	2e-45	180
tr:F3F3R3_PSEA0	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	28.87	568	351	17	8	540	5	554	2e-45	179
rs:WP_021653369	DNA topoisomerase III [Clostridiales bacterium oral taxon 876].	26.63	597	391	16	7	579	6	579	2e-45	181
rs:WP_032597189	DNA topoisomerase I [Bacteroides fragilis].	27.19	570	361	19	4	552	1	537	2e-45	181
rs:WP_022776439	DNA topoisomerase [Butyrivibrio sp. AE2015].	28.52	582	350	18	7	534	6	575	2e-45	184
rs:WP_009902112	DNA topoisomerase III [Burkholderia thailandensis].	27.81	561	370	15	7	550	6	548	2e-45	182
rs:WP_015807862	DNA topoisomerase III [Pedobacter heparinus].	28.87	568	338	18	7	543	4	536	2e-45	180
rs:WP_025141104	DNA topoisomerase III [Achromobacter sp. DH1f].	29.64	577	347	19	5	550	4	552	2e-45	182
rs:WP_032489173	type I topoisomerase [Enterococcus faecalis].	28.42	556	367	17	5	544	3	543	2e-45	181
tr:R5HV76_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.48	604	367	22	8	554	7	596	2e-45	181
rs:WP_028537582	DNA topoisomerase III [Paenibacillus sp. J14].	26.97	634	395	21	5	601	3	605	2e-45	181
rs:WP_004303817	DNA topoisomerase I [Bacteroides ovatus].	27.19	570	361	19	4	552	1	537	2e-45	181
rs:WP_016662202	DNA topoisomerase III [Bacteroides stercoris].	28.57	574	348	20	4	552	1	537	2e-45	181
rs:WP_044270609	DNA topoisomerase I [Candidatus Bacteroides timonensis].	28.75	574	347	20	4	552	1	537	3e-45	181
rs:WP_040581963	hypothetical protein [Sedimentibacter sp. B4].	27.94	569	350	20	7	550	4	537	3e-45	181
rs:WP_009447128	DNA topoisomerase III [Lachnospiraceae bacterium oral taxon 082].	27.11	568	354	14	3	550	2	529	3e-45	181
rs:WP_035482038	DNA topoisomerase III [Burkholderia phenoliruptrix].	27.73	559	373	15	7	550	6	548	3e-45	182
rs:WP_039996512	DNA topoisomerase III, partial [Flavonifractor plautii].	28.29	502	309	14	7	491	4	471	3e-45	177
rs:WP_014237640	topoisomerase IA [Azospira oryzae].	29.65	570	356	16	1	550	1	545	3e-45	181
rs:WP_022339504	DNA topoisomerase III [Bacteroides sp. CAG:714].	27.64	568	341	19	7	531	46	586	3e-45	181
rs:WP_033143458	DNA topoisomerase III [Blautia producta].	26.83	600	381	19	3	554	2	591	3e-45	181
rs:WP_034675203	DNA topoisomerase I [Chryseobacterium formosense].	26.11	586	364	15	4	552	1	554	3e-45	181
rs:WP_046740998	DNA topoisomerase III [Lampropedia sp. CT6].	28.72	578	348	20	3	531	2	564	3e-45	183
rs:WP_004342576	DNA topoisomerase I [Prevotella buccae].	27.19	570	351	16	5	550	3	532	3e-45	181
rs:WP_026490610	DNA topoisomerase III [Butyrivibrio sp. XPD2002].	27.85	614	368	20	5	554	4	606	3e-45	181
rs:WP_014078553	DNA topoisomerase III [Roseburia hominis].	26.58	568	359	15	1	549	1	529	3e-45	181
rs:WP_035055399	DNA topoisomerase III [Carnobacterium pleistocenium].	26.93	557	345	15	5	550	3	508	3e-45	181
rs:WP_007665430	DNA topoisomerase I [Bacteroides intestinalis].	27.80	572	355	17	4	552	1	537	3e-45	181
rs:WP_025799526	DNA topoisomerase III [Prevotella saccharolytica].	28.28	541	344	15	7	531	2	514	3e-45	181
rs:WP_045481397	DNA topoisomerase III [Bacillus sp. TS-2].	27.44	616	389	22	5	599	4	582	3e-45	181
rs:WP_007366263	DNA topoisomerase III [Porphyromonas uenonis].	28.92	574	341	19	1	544	1	537	3e-45	181
rs:WP_028362087	DNA topoisomerase III [Burkholderia sp. JPY366].	27.73	559	373	15	7	550	6	548	3e-45	182
rs:WP_040012714	DNA topoisomerase, partial [Peptostreptococcaceae bacterium ACC19a].	29.64	496	295	18	7	491	4	456	3e-45	177
rs:WP_013671195	DNA topoisomerase III [Prevotella denticola].	29.00	562	327	21	7	531	2	528	3e-45	180
tr:A4T0M8_POLSQ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.21	592	375	18	7	568	8	579	3e-45	182
rs:WP_009463602	MULTISPECIES: DNA topoisomerase III [Alcaligenes].	28.18	589	372	18	5	566	4	568	3e-45	182
rs:WP_009908309	DNA topoisomerase III [Burkholderia thailandensis].	27.81	561	370	15	7	550	6	548	3e-45	182
rs:WP_022438027	DNA topoisomerase III [Prevotella sp. CAG:279].	28.49	544	338	20	7	531	2	513	3e-45	180
rs:WP_009226172	DNA topoisomerase III [Paenibacillus sp. oral taxon 786].	26.97	634	395	21	5	601	3	605	3e-45	181
rs:WP_044132009	DNA topoisomerase I [Bacteroides fragilis].	26.82	604	394	18	4	591	1	572	3e-45	181
rs:WP_007662652	DNA topoisomerase I [Bacteroides intestinalis].	27.19	570	361	19	4	552	1	537	3e-45	181
rs:WP_025371025	DNA topoisomerase III [Advenella mimigardefordensis].	28.96	556	349	16	5	534	4	539	3e-45	182
tr:V6Q728_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.68	551	351	14	7	550	5	509	3e-45	181
rs:WP_023567376	DNA topoisomerase III, partial [Escherichia coli].	29.17	432	284	12	8	428	5	425	3e-45	177
rs:WP_044963946	DNA topoisomerase III [Clostridiaceae bacterium MS3].	27.26	620	369	22	7	554	6	615	3e-45	181
rs:WP_018596389	DNA topoisomerase III [Blautia producta].	27.17	600	379	18	3	554	2	591	3e-45	180
rs:WP_041690182	hypothetical protein, partial [Eubacterium limosum].	27.70	610	388	22	7	590	5	587	3e-45	180
rs:WP_031861022	DNA topoisomerase III, partial [Staphylococcus aureus].	30.36	504	320	15	43	536	14	496	3e-45	178
rs:WP_042971805	DNA topoisomerase I [Bacteroides fragilis].	27.19	570	361	19	4	552	1	537	3e-45	181
rs:WP_036854117	DNA topoisomerase III [Prevotella denticola].	29.13	563	325	22	7	531	2	528	3e-45	180
rs:WP_002352589	MULTISPECIES: DNA topoisomerase [Enterococcus].	28.42	556	367	17	5	544	3	543	3e-45	181
rs:WP_029468581	DNA topoisomerase III [Clostridiales bacterium VE202-06].	27.17	600	379	18	3	554	2	591	3e-45	180
rs:WP_013586805	DNA topoisomerase III [Burkholderia sp. CCGE1001].	27.73	559	373	15	7	550	6	548	3e-45	182
rs:WP_026570600	DNA topoisomerase [Bacillus sp. NSP22.2].	26.48	608	401	19	7	590	4	589	3e-45	181
rs:WP_017225403	DNA topoisomerase III [Cupriavidus basilensis].	28.02	596	377	20	7	577	6	574	3e-45	182
rs:WP_034219466	DNA topoisomerase, partial [Lachnospiraceae bacterium AC2014].	27.01	585	367	18	7	543	6	578	3e-45	180
rs:WP_046720418	DNA topoisomerase III [Pseudomonas syringae].	26.44	590	391	14	4	565	1	575	3e-45	181
rs:WP_042484801	DNA topoisomerase III [Alcaligenes faecalis].	28.18	589	372	18	5	566	4	568	3e-45	182
rs:WP_004293865	DNA topoisomerase I [Bacteroides eggerthii].	27.03	603	392	18	4	590	1	571	3e-45	180
rs:WP_016359756	MULTISPECIES: DNA topoisomerase III [Clostridiales].	27.26	620	369	22	7	554	6	615	3e-45	180
tr:Q2T2B5_BURTA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.81	561	370	15	7	550	28	570	3e-45	182
rs:WP_015001367	DNA topoisomerase III [Burkholderia phenoliruptrix].	27.73	559	373	15	7	550	6	548	3e-45	182
rs:WP_004295480	DNA topoisomerase I [Bacteroides eggerthii].	27.11	568	364	18	4	552	1	537	3e-45	180
rs:WP_029768989	hypothetical protein, partial [Ralstonia sp. JGI 0001001-A05].	27.24	569	356	17	7	553	4	536	3e-45	179
rs:WP_018478536	DNA topoisomerase III [Pontibacter roseus].	26.94	542	348	16	8	531	5	516	3e-45	181
rs:WP_008999438	DNA topoisomerase I [Bacteroides sp. D2].	27.75	573	363	17	7	558	4	546	3e-45	180
rs:WP_009132146	DNA topoisomerase III [Bacteroides oleiciplenus].	27.02	570	362	19	4	552	1	537	3e-45	180
rs:WP_016177605	DNA topoisomerase III [Enterococcus durans].	28.60	556	366	16	5	544	3	543	3e-45	180
rs:WP_037022461	MULTISPECIES: hypothetical protein, partial [Ralstonia].	27.24	569	356	17	7	553	4	536	3e-45	179
rs:WP_024565255	DNA topoisomerase III [Elizabethkingia anophelis].	28.86	537	340	17	8	531	5	512	3e-45	180
rs:WP_021997716	DNA topoisomerase [Ruminococcus sp. CAG:724].	29.24	595	345	19	4	555	1	562	3e-45	180
tr:U2JF73_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERJ78677.1};	28.70	554	336	20	8	531	21	545	3e-45	180
rs:WP_011222029	DNA topoisomerase [Lactobacillus plantarum].	27.69	632	389	21	5	603	3	599	3e-45	180
rs:WP_014298481	DNA topoisomerase I [Bacteroides fragilis].	28.75	574	347	20	4	552	1	537	3e-45	180
rs:WP_008810305	MULTISPECIES: DNA topoisomerase III [Parasutterella].	28.06	581	381	17	5	567	4	565	4e-45	181
rs:WP_016428507	DNA topoisomerase III [Paenisporosarcina sp. HGH0030].	28.08	552	365	14	7	544	5	538	4e-45	180
rs:WP_036287960	DNA topoisomerase III [Methylosinus sp. PW1].	26.64	608	387	15	5	582	3	581	4e-45	180
rs:WP_042897089	DNA topoisomerase III, partial [Enterobacter aerogenes].	28.78	542	337	15	34	543	6	530	4e-45	181
rs:WP_008015944	DNA topoisomerase, partial [Bacteroides xylanisolvens].	27.99	561	358	17	4	550	1	529	4e-45	178
rs:WP_000542405	topoisomerase III [Bacillus cereus].	30.37	563	327	19	5	531	4	537	4e-45	180
rs:WP_016312076	DNA topoisomerase III [Paenibacillus barengoltzii].	26.66	634	397	20	5	601	3	605	4e-45	181
rs:WP_010539317	DNA topoisomerase III [Bacteroides faecis].	26.93	557	354	17	7	531	2	537	4e-45	180
rs:WP_021885805	DNA topoisomerase [Clostridium sp. CAG:590].	27.47	597	379	18	8	560	16	602	4e-45	180
rs:WP_006780354	DNA topoisomerase III [[Clostridium] hathewayi].	25.92	598	360	17	8	532	7	594	4e-45	180
rs:WP_008917977	DNA topoisomerase III [Burkholderia sp. H160].	27.24	580	385	16	7	568	6	566	4e-45	182
rs:WP_011485578	DNA topoisomerase III [Polaromonas sp. JS666].	27.21	599	387	15	5	568	3	587	4e-45	182
rs:WP_032570624	DNA topoisomerase I [Bacteroides fragilis].	29.03	565	349	19	4	550	1	531	4e-45	180
rs:WP_021940547	DNA topoisomerase III [Bacteroides eggerthii CAG:109].	26.90	565	353	19	7	531	2	546	4e-45	180
rs:WP_039630371	DNA topoisomerase [Clostridium argentinense].	28.30	636	393	22	7	603	5	616	4e-45	180
rs:WP_004606705	DNA topoisomerase III [[Clostridium] scindens].	27.39	595	375	20	8	554	7	592	4e-45	180
tr:V4ZF16_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.77	533	354	13	35	550	10	528	4e-45	181
rs:WP_008618622	DNA topoisomerase III [Paraprevotella clara].	27.30	564	349	17	7	531	2	543	4e-45	180
rs:WP_005956335	DNA topoisomerase III [Peptoniphilus harei].	26.94	542	344	15	7	539	4	502	4e-45	179
rs:WP_029429174	DNA topoisomerase III [Bacteroides cellulosilyticus].	27.21	566	350	20	7	531	2	546	4e-45	180
rs:WP_028462024	DNA topoisomerase III [Nitrosomonas cryotolerans].	29.46	577	343	20	7	550	6	551	4e-45	181
rs:WP_002343776	MULTISPECIES: DNA topoisomerase III [Lactobacillales].	28.24	556	368	15	5	544	3	543	4e-45	180
rs:WP_018361007	DNA topoisomerase III [Porphyromonas macacae].	27.80	572	350	20	7	550	2	538	4e-45	180
rs:WP_007210360	DNA topoisomerase III [Bacteroides cellulosilyticus].	27.21	566	350	20	7	531	2	546	4e-45	180
rs:WP_040427949	DNA topoisomerase III, partial [Acetivibrio cellulolyticus].	29.06	523	328	17	7	514	6	500	4e-45	177
rs:WP_039407184	DNA topoisomerase III [Pandoraea pulmonicola].	28.45	601	367	21	7	571	6	579	4e-45	181
rs:WP_004288554	DNA topoisomerase III [Bacteroides eggerthii].	26.90	565	353	19	7	531	2	546	4e-45	180
rs:WP_047209919	DNA topoisomerase [Streptococcus agalactiae].	27.29	579	355	17	7	569	5	533	4e-45	179
rs:WP_029969429	DNA topoisomerase III [Burkholderia sp. URHA0054].	28.29	562	366	17	7	550	6	548	4e-45	181
rs:WP_042230926	DNA topoisomerase [Peptoniphilus senegalensis].	28.03	553	323	19	7	539	6	503	4e-45	179
tr:E0RWM5_BUTPB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.79	583	354	20	7	536	6	574	4e-45	183
rs:WP_006050553	DNA topoisomerase III [Burkholderia graminis].	27.91	559	372	15	7	550	6	548	4e-45	181
rs:WP_006906929	DNA topoisomerase III [Shuttleworthia satelles].	27.90	552	325	18	7	539	4	501	4e-45	179
rs:WP_009435078	DNA topoisomerase III [Prevotella sp. oral taxon 306].	27.99	568	329	21	8	531	5	536	4e-45	179
rs:WP_027199369	DNA topoisomerase III [Burkholderia sprentiae].	28.32	565	362	18	7	550	6	548	4e-45	181
rs:WP_013337716	DNA topoisomerase III [Burkholderia sp. CCGE1003].	28.11	562	367	17	7	550	6	548	5e-45	181
rs:WP_024396453	DNA topoisomerase [Streptococcus suis].	27.48	575	359	17	7	569	5	533	5e-45	179
rs:WP_025335202	DNA topoisomerase III [Paenibacillus sabinae].	26.87	629	391	20	5	599	3	596	5e-45	180
rs:WP_028211930	DNA topoisomerase III [Burkholderia mimosarum].	27.79	583	378	16	7	568	6	566	5e-45	181
rs:WP_033017430	DNA topoisomerase III [Geobacillus stearothermophilus].	28.66	464	307	11	94	544	17	469	5e-45	179
rs:WP_024380179	hypothetical protein [Streptococcus suis].	25.25	610	385	19	5	590	3	565	5e-45	179
rs:WP_014008078	DNA topoisomerase III [Collimonas fungivorans].	28.35	568	371	16	3	550	2	553	5e-45	181
rs:WP_008753349	DNA topoisomerase III [Lachnoanaerobaculum saburreum].	26.89	647	378	26	8	590	6	621	5e-45	179
rs:WP_039011607	DNA topoisomerase III [Cupriavidus sp. IDO].	28.33	600	372	20	7	577	6	576	5e-45	181
rs:WP_039310032	DNA topoisomerase III, partial [Clostridium botulinum].	29.68	465	284	13	117	559	5	448	5e-45	179
rs:WP_006036811	DNA topoisomerase III [Paenibacillus curdlanolyticus].	26.38	633	395	20	5	603	3	598	5e-45	180
rs:WP_032972388	DNA topoisomerase III [Bordetella hinzii].	29.37	572	355	19	5	550	4	552	5e-45	181
rs:WP_008592302	DNA topoisomerase III [Salimicrobium sp. MJ3].	27.32	560	365	15	7	548	6	541	5e-45	180
rs:WP_009548295	DNA topoisomerase III [Burkholderiales bacterium JOSHI_001].	28.02	596	372	22	7	567	6	579	5e-45	181
rs:WP_032962115	DNA topoisomerase III [Bordetella hinzii].	29.37	572	355	19	5	550	4	552	5e-45	181
rs:WP_036304041	DNA topoisomerase [Methylomicrobium agile].	28.20	539	348	17	4	531	1	511	5e-45	180
rs:WP_025598065	DNA topoisomerase III [Burkholderia sp. WSM2230].	28.11	562	367	17	7	550	6	548	5e-45	181
rs:WP_032532316	hypothetical protein, partial [Streptococcus suis].	25.25	610	385	19	5	590	3	565	5e-45	179
tr:H8GM49_METAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.20	539	348	17	4	531	1	511	5e-45	179
rs:WP_004313571	MULTISPECIES: DNA topoisomerase III [Bacteroides].	26.67	555	359	15	7	531	2	538	5e-45	180
rs:WP_042883607	DNA topoisomerase III [Cupriavidus necator].	28.12	601	372	20	7	577	6	576	5e-45	181
rs:WP_032978941	DNA topoisomerase III [Bordetella hinzii].	29.37	572	355	19	5	550	4	552	5e-45	181
rs:WP_021253879	DNA topoisomerase III [Paenibacillus alvei].	26.28	647	396	19	5	603	3	616	5e-45	180
rs:WP_017170279	hypothetical protein, partial [Xanthomonas axonopodis].	27.40	489	317	12	87	548	11	488	5e-45	179
rs:WP_029577833	DNA topoisomerase III [Bordetella hinzii].	29.37	572	355	19	5	550	4	552	5e-45	181
rs:WP_032957599	DNA topoisomerase III [Bordetella hinzii].	29.37	572	355	19	5	550	4	552	5e-45	181
rs:WP_042988115	DNA topoisomerase I [Bacteroides fragilis].	26.82	604	394	18	4	591	1	572	5e-45	180
rs:WP_040578486	DNA topoisomerase, partial [Methylomicrobium album].	28.20	539	348	17	4	531	1	511	5e-45	179
rs:WP_018676469	DNA topoisomerase I [Riemerella columbina].	26.82	604	394	18	4	591	1	572	5e-45	180
rs:WP_043223945	DNA topoisomerase III [Bordetella hinzii].	29.37	572	355	19	5	550	4	552	5e-45	181
rs:WP_004319201	MULTISPECIES: DNA topoisomerase I [Bacteroides].	27.11	568	364	18	4	552	1	537	5e-45	180
rs:WP_035554140	DNA topoisomerase III [Burkholderia sp. 9120].	28.11	562	367	17	7	550	6	548	5e-45	181
rs:WP_021325878	DNA topoisomerase III [Photorhabdus temperata].	26.88	584	371	18	7	557	4	564	5e-45	180
rs:WP_024469514	hypothetical protein [Treponema pedis].	28.62	559	356	19	7	549	4	535	5e-45	179
rs:WP_036172716	DNA topoisomerase III [Massilia sp. 9096].	28.92	567	358	18	7	550	6	550	5e-45	181
rs:WP_029486035	DNA topoisomerase [Enterococcus gallinarum].	28.42	556	367	16	5	544	3	543	6e-45	180
tr:D6D8L2_9BACE	SubName: Full=Bacteroides xylanisolvens XB1A draft genome {ECO:0000313|EMBL:CBK66357.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBK66357.1};	26.49	555	360	15	7	531	2	538	6e-45	180
rs:WP_029527029	DNA topoisomerase III [Polaromonas glacialis].	27.84	589	363	18	5	550	3	572	6e-45	182
rs:WP_025726041	DNA topoisomerase III [Bacteroides sp. 14(A)].	27.21	566	350	20	7	531	2	546	6e-45	180
rs:WP_007482644	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.57	574	348	20	4	552	1	537	6e-45	179
rs:WP_047201597	DNA topoisomerase [Streptococcus agalactiae].	27.66	564	346	17	4	550	2	520	6e-45	179
rs:WP_025604343	DNA topoisomerase III [Pontibacter actiniarum].	26.82	548	351	17	4	531	1	518	6e-45	180
rs:WP_008024816	MULTISPECIES: DNA topoisomerase III [Bacteroides].	26.67	555	359	15	7	531	2	538	6e-45	180
rs:WP_009011127	DNA topoisomerase III [Prevotella sp. C561].	28.83	555	335	18	8	531	5	530	6e-45	179
rs:WP_032588335	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.57	574	348	20	4	552	1	537	6e-45	179
rs:WP_016212888	DNA topoisomerase III [Parabacteroides goldsteinii].	27.02	570	362	19	4	552	1	537	6e-45	179
rs:WP_045241973	DNA topoisomerase III [Burkholderiaceae bacterium 16].	28.25	570	357	19	7	550	6	549	6e-45	181
rs:WP_026432170	DNA topoisomerase III [Acidovorax oryzae].	28.71	606	367	24	5	568	4	586	6e-45	182
rs:WP_026508071	DNA topoisomerase III [Butyrivibrio sp. MC2013].	27.71	563	329	20	7	539	4	518	6e-45	179
rs:WP_046409534	DNA topoisomerase III [Bacteroides sp. N54.MGS-20].	27.74	530	349	14	8	531	5	506	6e-45	179
rs:WP_000765173	DNA topoisomerase III [Escherichia coli].	28.95	563	354	17	7	540	4	549	6e-45	179
rs:WP_009038766	DNA topoisomerase III [Bacteroides sp. D22].	26.49	555	360	15	7	531	2	538	6e-45	179
rs:WP_033150038	DNA topoisomerase III [Prevotella sp. RM4].	28.39	560	328	21	7	531	2	523	6e-45	179
tr:A0A095FRA6_BURML	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.93	560	346	19	5	543	3	531	6e-45	180
rs:WP_018662197	DNA topoisomerase III [Bacillus acidiproducens].	28.37	557	334	19	7	548	5	511	6e-45	179
rs:WP_006906961	DNA topoisomerase [Shuttleworthia satelles].	28.12	544	318	18	7	531	4	493	6e-45	178
rs:WP_044527626	DNA topoisomerase III [Escherichia coli].	28.95	563	354	17	7	540	4	549	6e-45	179
rs:WP_033143219	DNA topoisomerase III [Blautia producta].	27.03	592	353	21	7	566	4	548	7e-45	179
rs:WP_032967783	DNA topoisomerase III [Bordetella holmesii].	29.19	555	342	17	5	531	4	535	7e-45	181
rs:WP_027793206	DNA topoisomerase III [Burkholderia acidipaludis].	27.29	579	386	15	7	568	6	566	7e-45	181
rs:WP_024741910	DNA topoisomerase III [Tenacibaculum maritimum].	27.42	547	341	18	8	531	5	518	7e-45	180
rs:WP_007218955	DNA topoisomerase III [Bacteroides cellulosilyticus].	27.21	566	350	20	7	531	2	546	7e-45	179
rs:WP_009218495	DNA topoisomerase III [Lachnospiraceae oral taxon 107].	25.98	639	396	24	8	590	6	623	7e-45	179
rs:WP_026067918	DNA topoisomerase III [Pusillimonas noertemannii].	27.27	605	394	16	7	592	6	583	7e-45	181
rs:WP_004293951	DNA topoisomerase III [Bacteroides eggerthii].	26.90	565	353	19	7	531	2	546	7e-45	179
rs:WP_009510834	DNA topoisomerase [Opitutaceae bacterium TAV5].	27.85	578	345	17	4	539	1	548	7e-45	180
rs:WP_034374893	DNA topoisomerase III [Comamonas testosteroni].	27.77	605	373	21	5	568	4	585	7e-45	181
rs:WP_041485226	DNA topoisomerase III [beta proteobacterium CB].	27.60	616	397	18	7	590	2	600	7e-45	181
rs:WP_017184069	conjugal transfer protein TraE [Sphingobium xenophagum].	25.82	577	374	14	1	548	1	552	7e-45	179
rs:WP_004325469	DNA topoisomerase I [Bacteroides ovatus].	28.22	574	350	20	4	552	1	537	7e-45	179
rs:WP_044322592	DNA topoisomerase III, partial [Pseudomonas amygdali].	28.87	568	351	17	8	540	5	554	7e-45	178
rs:WP_044396211	DNA topoisomerase III [Acidovorax temperans].	28.10	612	361	23	5	568	4	584	7e-45	181
rs:WP_028227275	DNA topoisomerase III [Burkholderia ferrariae].	27.46	579	385	16	7	568	6	566	7e-45	181
rs:WP_033872237	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	35.27	292	171	6	276	552	31	319	7e-45	175
rs:WP_022275766	DNA topoisomerase III [Bacteroides finegoldii CAG:203].	27.08	565	345	18	7	531	2	539	7e-45	179
rs:WP_035070160	DNA topoisomerase III [Anditalea andensis].	29.87	539	328	21	8	531	5	508	7e-45	179
rs:WP_026334985	DNA topoisomerase III [Oxalobacteraceae bacterium AB_14].	29.41	578	350	21	5	550	4	555	7e-45	181
rs:WP_031943130	DNA processing protein [uncultured bacterium].	26.39	576	368	17	7	548	7	560	7e-45	179
rs:WP_041701982	DNA topoisomerase III [Gottschalkia acidurici].	29.19	579	338	21	8	532	7	567	7e-45	180
rs:WP_022328708	DNA topoisomerase III [Prevotella sp. CAG:732].	27.50	589	320	23	7	531	2	547	7e-45	179
rs:WP_017450116	MULTISPECIES: DNA topoisomerase III [Herbaspirillum].	28.37	578	359	17	3	550	2	554	7e-45	181
rs:WP_004312405	DNA topoisomerase III [Bacteroides ovatus].	26.31	555	360	16	7	531	2	537	7e-45	179
rs:WP_028533041	DNA topoisomerase III [Paenibacillus sp. UNC217MF].	26.43	647	395	19	5	603	3	616	7e-45	180
rs:WP_004353362	DNA topoisomerase III [Prevotella denticola].	29.00	562	327	21	7	531	2	528	7e-45	179
rs:WP_036851975	DNA topoisomerase III [Porphyromonas macacae].	27.51	578	357	20	7	557	2	544	7e-45	179
tr:M1T6W7_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.60	616	397	18	7	590	24	622	7e-45	181
rs:WP_024418977	DNA topoisomerase [Streptococcus suis].	26.87	603	389	16	7	599	5	565	7e-45	178
rs:WP_042305031	DNA topoisomerase III [Burkholderia terrae].	27.81	561	370	16	7	550	6	548	7e-45	181
tr:K0B0G9_CLOA9	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.19	579	338	21	8	532	11	571	7e-45	180
rs:WP_032593111	DNA topoisomerase I [Bacteroides fragilis].	29.03	565	349	19	4	550	1	531	7e-45	179
rs:WP_043610175	DNA topoisomerase III, partial [Desulfovibrio sp. A2].	25.84	596	386	15	5	564	4	579	7e-45	179
rs:WP_029486090	DNA topoisomerase [Enterococcus gallinarum].	28.73	557	364	17	5	544	3	543	7e-45	179
rs:WP_039472425	DNA topoisomerase I [Pedobacter kyungheensis].	28.98	566	340	18	7	543	4	536	7e-45	179
rs:WP_011205815	MULTISPECIES: DNA topoisomerase [Proteobacteria].	26.39	576	368	17	7	548	7	560	7e-45	179
tr:F3J5T5_PSEAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	34.82	336	202	7	86	412	3	330	8e-45	172
rs:WP_005017120	DNA topoisomerase III [Bordetella holmesii].	29.19	555	342	17	5	531	4	535	8e-45	181
rs:WP_032584277	DNA topoisomerase I [Bacteroides fragilis].	29.03	565	349	19	4	550	1	531	8e-45	179
rs:WP_044912868	DNA topoisomerase III [Butyrivibrio sp. WCE2006].	27.12	612	372	19	5	554	4	603	8e-45	179
rs:WP_026630256	DNA topoisomerase III [Dyadobacter alkalitolerans].	28.28	541	336	17	8	531	5	510	8e-45	179
rs:WP_002585092	DNA topoisomerase III [[Clostridium] clostridioforme].	27.62	583	354	17	7	563	6	546	8e-45	179
rs:WP_005881848	DNA topoisomerase III [Oxalobacter formigenes].	28.98	597	368	23	5	571	4	574	8e-45	181
tr:D4JQ77_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.67	571	371	21	7	552	20	573	8e-45	180
tr:A0A0A0M4X3_9LACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.34	469	279	16	29	473	3	452	8e-45	177
rs:WP_035208559	DNA topoisomerase III, partial [Acidovorax avenae].	28.71	606	367	24	5	568	4	586	8e-45	181
rs:WP_009428925	DNA topoisomerase III [Oribacterium sp. oral taxon 108].	27.26	598	376	22	7	555	5	592	8e-45	179
rs:WP_013617264	DNA topoisomerase III [Bacteroides salanitronis].	27.45	561	348	18	7	531	2	539	8e-45	179
rs:WP_017648987	hypothetical protein, partial [Streptococcus agalactiae].	30.58	497	278	16	4	472	2	459	8e-45	176
rs:WP_020750047	DNA topoisomerase III [Ralstonia solanacearum].	27.75	627	401	20	7	606	6	607	8e-45	181
rs:WP_024221956	DNA topoisomerase III [Escherichia coli].	29.00	562	353	17	8	540	5	549	8e-45	179
rs:WP_023043465	hypothetical protein [Photorhabdus temperata].	26.93	557	353	17	7	530	4	539	8e-45	179
rs:WP_035865596	DNA topoisomerase III [Cupriavidus sp. SK-3].	28.25	570	357	19	7	550	6	549	8e-45	181
rs:WP_032563947	DNA topoisomerase I [Bacteroides fragilis].	26.82	604	394	18	4	591	1	572	8e-45	179
rs:WP_008620097	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	27.11	568	364	18	4	552	1	537	8e-45	179
rs:WP_018752813	DNA topoisomerase III [Paenibacillus sanguinis].	26.65	638	394	22	5	600	3	608	8e-45	179
rs:WP_034705127	DNA topoisomerase III [Chryseobacterium luteum].	29.17	545	331	20	8	531	5	515	8e-45	179
tr:W7CFI9_BROTH	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	27.67	571	362	20	7	559	5	542	8e-45	179
rs:WP_044907652	DNA topoisomerase III [[Clostridium] innocuum].	26.42	564	353	15	7	549	4	526	8e-45	179
rs:WP_039671403	DNA topoisomerase [Streptococcus macedonicus].	26.73	550	347	16	4	539	2	509	9e-45	178
rs:WP_022583212	DNA topoisomerase III family protein [Peptoclostridium difficile].	25.96	570	360	15	1	549	1	529	9e-45	179
rs:WP_013548841	DNA topoisomerase III [Bacteroides helcogenes].	26.63	567	354	19	7	531	2	548	9e-45	179
rs:WP_032826676	DNA topoisomerase III [Bordetella holmesii].	29.19	555	342	17	5	531	4	535	9e-45	181
rs:WP_022383850	DNA topoisomerase III [Bacteroides sp. CAG:462].	26.58	587	335	19	7	531	2	554	9e-45	179
tr:D1W4E5_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.78	605	395	18	3	591	19	591	9e-45	179
rs:WP_005790822	MULTISPECIES: DNA topoisomerase I [Bacteroidetes].	26.82	604	394	18	4	591	1	572	9e-45	179
rs:WP_035790822	DNA topoisomerase III [Butyrivibrio sp. FC2001].	27.69	614	369	20	5	554	4	606	9e-45	179
tr:C5A9D2_BURGB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.61	590	360	16	10	539	7	583	9e-45	179
rs:WP_046414281	DNA topoisomerase III [Bacteroides sp. UNK.MGS-13].	27.74	530	349	14	8	531	5	506	9e-45	179
rs:WP_015016310	DNA topoisomerase III [Acidovorax sp. KKS102].	28.27	612	360	23	5	568	4	584	9e-45	181
tr:A7LZL4_BACO1	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EDO11386.1};	26.31	555	360	16	7	531	2	537	9e-45	179
rs:WP_044063820	DNA topoisomerase III [Prevotella saccharolytica].	28.28	541	344	15	7	531	2	514	9e-45	179
rs:WP_035357163	ATP-dependent DNA helicase RecQ [Edaphobacter aggregans].	29.16	583	357	19	2	548	6	568	1e-44	182
rs:WP_004797795	DNA topoisomerase III [[Eubacterium] dolichum].	26.14	570	359	15	1	549	1	529	1e-44	179
rs:WP_010739950	DNA topoisomerase III [Enterococcus malodoratus].	26.61	560	337	17	7	550	5	506	1e-44	179
rs:WP_038167760	DNA topoisomerase III [Verrucomicrobium sp. BvORR106].	29.46	577	333	24	3	531	2	552	1e-44	180
rs:WP_019150869	DNA topoisomerase I [Alistipes senegalensis].	26.49	619	401	19	4	602	1	585	1e-44	179
rs:WP_029321244	DNA topoisomerase III, partial [Butyrivibrio sp. AE3004].	26.35	611	378	18	5	554	4	603	1e-44	179
rs:WP_036027634	DNA topoisomerase III [Brochothrix thermosphacta].	27.67	571	362	20	7	559	5	542	1e-44	179
rs:WP_042198563	DNA topoisomerase III [Paenibacillus sp. G4].	26.61	635	398	18	5	600	3	608	1e-44	179
rs:WP_032559101	MULTISPECIES: DNA topoisomerase I [Bacteroides].	26.66	604	395	18	4	591	1	572	1e-44	179
rs:WP_004798049	DNA topoisomerase III [[Eubacterium] dolichum].	25.96	570	360	15	1	549	1	529	1e-44	179
rs:WP_024997486	DNA topoisomerase III [Bacteroides graminisolvens].	27.32	560	349	18	7	531	2	538	1e-44	179
rs:WP_036873209	DNA topoisomerase III [Porphyromonas macacae].	27.62	572	351	20	7	550	2	538	1e-44	179
rs:WP_007179718	DNA topoisomerase III [Burkholderia sp. Ch1-1].	27.94	562	368	17	7	550	6	548	1e-44	180
tr:H1PME7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.71	505	288	18	7	491	44	496	1e-44	176
rs:WP_007039216	DNA topoisomerase III [Thiorhodococcus drewsii].	28.93	560	341	18	7	539	5	534	1e-44	180
rs:WP_006775893	DNA topoisomerase III [[Clostridium] hathewayi].	26.06	564	355	15	7	549	7	529	1e-44	179
rs:WP_002590573	MULTISPECIES: DNA topoisomerase III [Lachnospiraceae].	27.55	548	335	14	7	532	6	513	1e-44	179
rs:WP_040227551	DNA topoisomerase III, partial [Bhargavaea cecembensis].	28.81	486	304	17	3	473	2	460	1e-44	176
rs:WP_005797214	DNA topoisomerase III [Acidovorax delafieldii].	28.27	612	360	23	5	568	4	584	1e-44	181
rs:WP_010731205	DNA topoisomerase III [Enterococcus faecium].	28.24	556	368	16	5	544	3	543	1e-44	179
rs:WP_044593794	DNA topoisomerase III, partial [Cronobacter sakazakii].	28.11	434	288	13	7	428	4	425	1e-44	175
rs:WP_011689341	ATP-dependent DNA helicase RecQ [Candidatus Solibacter usitatus].	25.84	592	373	16	2	552	6	572	1e-44	182
rs:WP_047218931	DNA topoisomerase III [Delftia lacustris].	28.12	608	370	22	5	568	4	588	1e-44	181
rs:WP_022199129	DNA topoisomerase III [Bacteroides ovatus CAG:22].	26.31	555	360	16	7	531	2	537	1e-44	179
tr:D4KA47_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.71	564	357	15	7	549	6	528	1e-44	179
tr:E3GMG1_EUBLK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.70	610	388	22	7	590	5	587	1e-44	179
tr:D8P0T1_RALSL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.38	621	406	18	7	606	6	602	1e-44	180
rs:WP_013444792	DNA topoisomerase III [Paludibacter propionicigenes].	28.57	546	333	18	7	531	2	511	1e-44	178
rs:WP_017648495	DNA topoisomerase [Streptococcus agalactiae].	27.21	621	379	22	4	602	2	571	1e-44	177
rs:WP_034728006	DNA topoisomerase III [Chryseobacterium sp. JM1].	29.17	545	331	20	8	531	5	515	1e-44	179
tr:L1NI24_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.28	541	344	15	7	531	24	536	1e-44	179
rs:WP_008759619	DNA topoisomerase I [Bacteroides sp. 1_1_14].	27.53	603	381	19	4	592	1	561	1e-44	179
tr:D4JTZ1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.71	564	357	15	7	549	7	529	1e-44	179
rs:WP_009222474	DNA topoisomerase III [Peptoniphilus sp. oral taxon 386].	27.86	542	338	17	7	539	6	503	1e-44	177
rs:WP_039695713	DNA topoisomerase [Streptococcus gallolyticus].	26.47	563	358	16	4	552	2	522	1e-44	177
rs:WP_022389358	DNA topoisomerase III [Ruminococcus obeum CAG:39].	26.87	603	373	21	8	554	7	597	1e-44	179
rs:WP_033874157	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	35.27	292	171	6	276	552	32	320	1e-44	175
rs:WP_004321870	MULTISPECIES: DNA topoisomerase III [Bacteroides].	26.31	555	360	16	7	531	2	537	1e-44	179
rs:WP_026597778	DNA topoisomerase III [Methylocystis sp. LW5].	26.40	606	385	15	5	579	3	578	1e-44	179
rs:WP_008728394	DNA topoisomerase III [Erysipelotrichaceae bacterium 2_2_44A].	26.23	568	361	15	1	549	1	529	1e-44	179
rs:WP_046290345	DNA topoisomerase III [Pandoraea oxalativorans].	28.55	599	369	21	7	571	6	579	1e-44	180
rs:WP_036978385	DNA topoisomerase III [Pseudobutyrivibrio sp. MD2005].	28.09	566	333	18	7	539	4	528	1e-44	178
rs:WP_004306716	MULTISPECIES: DNA topoisomerase III [Bacteroides].	26.31	555	360	16	7	531	2	537	1e-44	179
rs:WP_035674877	DNA topoisomerase III, partial [Azospirillum brasilense].	27.48	644	370	25	5	603	3	594	1e-44	178
rs:WP_035561877	hypothetical protein [Halomonas sp. KO116].	28.74	595	357	23	1	548	1	575	1e-44	179
rs:WP_047193235	DNA topoisomerase III [[Polyangium] brachysporum].	28.26	598	370	22	7	567	6	581	1e-44	180
rs:WP_040555026	DNA topoisomerase III [Prevotella multiformis].	28.24	556	340	21	7	531	2	529	1e-44	178
tr:G3A3B1_9RALS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.38	621	406	18	7	606	6	602	1e-44	180
tr:W2CPA6_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.64	548	356	16	8	539	5	522	1e-44	177
rs:WP_013596902	DNA topoisomerase III [Acidovorax avenae].	28.71	606	367	24	5	568	4	586	1e-44	181
rs:WP_007362128	DNA topoisomerase [Opitutaceae bacterium TAV1].	27.85	578	345	17	4	539	1	548	1e-44	179
rs:WP_008016669	DNA topoisomerase, partial [Bacteroides xylanisolvens].	29.35	535	320	18	43	552	8	509	1e-44	178
rs:WP_020067280	DNA topoisomerase III [Burkholderia bryophila].	27.94	562	368	17	7	550	6	548	1e-44	180
rs:WP_004326163	DNA topoisomerase III [Bacteroides ovatus].	26.31	555	360	16	7	531	2	537	1e-44	179
rs:WP_026891460	DNA topoisomerase III [[Clostridium] aerotolerans].	26.64	593	352	22	8	532	7	584	1e-44	178
gp:HF952106_658	DNA topoisomerase III [Streptococcus agalactiae ILRI112]	26.51	611	389	19	7	604	4	567	1e-44	177
rs:WP_020313368	DNA topoisomerase III [Pseudomonas syringae].	28.87	568	351	17	8	540	5	554	1e-44	179
tr:D5HIG2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.27	550	346	16	7	539	4	516	1e-44	179
rs:WP_030102534	DNA topoisomerase III [Burkholderia sp. K24].	27.73	559	373	15	7	550	6	548	1e-44	180
rs:WP_005680567	DNA topoisomerase I [Bacteroides caccae].	27.48	604	381	19	4	592	1	562	1e-44	178
tr:G2ZP25_9RALS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.38	621	406	18	7	606	6	602	1e-44	180
rs:WP_034490094	DNA topoisomerase III [Butyrivibrio fibrisolvens].	28.32	565	334	17	7	539	4	529	1e-44	178
rs:WP_044427394	DNA topoisomerase III [Skermanella aerolata].	27.86	585	342	19	5	550	3	546	1e-44	179
rs:WP_028197702	DNA topoisomerase III [Burkholderia fungorum].	27.73	559	373	15	7	550	6	548	1e-44	180
rs:WP_022210148	DNA topoisomerase III [Bacteroides cellulosilyticus CAG:158].	27.21	566	350	20	7	531	2	546	1e-44	179
rs:WP_011466216	DNA topoisomerase III [Rhodoferax ferrireducens].	28.64	604	346	23	5	550	3	579	1e-44	181
rs:WP_019124129	DNA topoisomerase [Peptoniphilus grossensis].	26.51	611	389	19	7	604	4	567	1e-44	177
rs:WP_041954170	DNA topoisomerase [Parvimonas micra].	29.10	543	330	19	7	539	4	501	1e-44	177
rs:WP_018341696	DNA topoisomerase III [Cytophaga aurantiaca].	29.39	541	332	17	8	531	5	512	1e-44	178
rs:WP_037982365	DNA topoisomerase III, partial [Tannerella sp. oral taxon BU063].	26.64	548	356	16	8	539	5	522	1e-44	177
rs:WP_005833152	MULTISPECIES: DNA topoisomerase III [Bacteroides].	27.21	566	351	18	7	531	2	547	1e-44	179
rs:WP_018026660	hypothetical protein [Oligella urethralis].	29.11	560	347	17	3	534	2	539	1e-44	179
rs:WP_010464480	DNA topoisomerase III [Acidovorax radicis].	28.27	612	360	23	5	568	4	584	1e-44	181
rs:WP_036559719	DNA topoisomerase III [Oligella urethralis].	29.11	560	347	17	3	534	2	539	2e-44	179
tr:Q21RE9_RHOFT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.64	604	346	23	5	550	18	594	2e-44	181
rs:WP_043588193	DNA topoisomerase [Diplosphaera colitermitum].	27.75	591	342	16	4	539	1	561	2e-44	179
rs:WP_009855757	DNA topoisomerase III [Rubrivivax benzoatilyticus].	28.45	608	362	24	5	567	4	583	2e-44	179
rs:WP_006255133	DNA topoisomerase III [Alloprevotella tannerae].	28.17	600	379	22	7	582	2	573	2e-44	178
rs:WP_009461692	hypothetical protein [Lachnospiraceae bacterium 2_1_46FAA].	25.62	609	384	19	7	590	4	568	2e-44	178
rs:WP_016308801	DNA topoisomerase III [Enterorhabdus caecimuris].	25.18	564	374	15	7	548	4	541	2e-44	178
rs:WP_046850419	DNA topoisomerase III [Nitrosomonas communis].	28.67	565	363	18	7	550	6	551	2e-44	179
rs:WP_011797628	DNA topoisomerase III [Acidovorax citrulli].	28.71	606	367	24	5	568	4	586	2e-44	181
rs:WP_021891241	DNA topoisomerase III, partial [Bacteroides sp. CAG:20].	27.74	530	349	14	8	531	31	532	2e-44	178
rs:WP_018029103	hypothetical protein [Porphyromonas somerae].	27.96	565	357	17	8	553	5	538	2e-44	177
rs:WP_000108742	MULTISPECIES: hypothetical protein [Lactobacillales].	28.85	558	362	17	5	544	3	543	2e-44	178
rs:WP_022026173	DNA topoisomerase III [Clostridium sp. CAG:75].	26.10	659	406	24	7	598	6	650	2e-44	178
rs:WP_011189858	DNA topoisomerase III [Desulfotalea psychrophila].	29.01	624	374	24	1	592	1	587	2e-44	179
rs:WP_028993922	DNA topoisomerase III [Azonexus hydrophilus].	28.03	585	350	20	7	550	6	560	2e-44	179
rs:WP_036885935	DNA topoisomerase III [Prevotella bivia].	27.32	549	348	17	8	531	5	527	2e-44	177
rs:WP_012789015	DNA topoisomerase III [Chitinophaga pinensis].	29.05	537	337	17	8	531	5	510	2e-44	178
rs:WP_025019241	DNA topoisomerase I [Bacteroides sartorii].	28.22	574	350	20	4	552	1	537	2e-44	178
rs:WP_042355746	DNA topoisomerase III [Bacillus sp. MT2].	26.70	543	359	17	7	530	4	526	2e-44	178
rs:WP_021243382	conjugal transfer protein TraE [Sphingobium baderi].	25.65	577	375	14	1	548	1	552	2e-44	178
rs:WP_011586942	DNA topoisomerase III [Cytophaga hutchinsonii].	29.83	543	326	19	8	531	5	511	2e-44	178
tr:N9XV23_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.82	550	360	17	7	540	4	532	2e-44	177
rs:WP_043003296	DNA topoisomerase III [Comamonas testosteroni].	27.93	605	372	21	5	568	4	585	2e-44	180
rs:WP_004228801	DNA topoisomerase III [Lysinibacillus fusiformis].	27.46	579	360	20	7	556	6	553	2e-44	178
rs:WP_026773238	DNA topoisomerase I [Sediminibacterium sp. OR43].	28.60	556	330	19	4	531	1	517	2e-44	178
tr:F0F5I7_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.24	556	340	21	7	531	94	621	2e-44	178
rs:WP_046060633	DNA topoisomerase III [Acidovorax citrulli].	28.71	606	367	24	5	568	4	586	2e-44	180
rs:WP_022242126	DNA topoisomerase [Clostridium sp. CAG:413].	27.29	634	394	20	4	604	1	600	2e-44	178
rs:WP_019188572	DNA topoisomerase III [Candidatus Prevotella conceptionensis].	28.23	549	335	21	7	531	2	515	2e-44	178
rs:WP_017382019	hypothetical protein [Paenisporosarcina sp. TG-14].	28.47	562	358	19	7	548	5	542	2e-44	178
rs:WP_044278434	ATP-dependent DNA helicase RecQ [Myxococcus stipitatus].	27.49	593	342	20	3	531	23	591	2e-44	182
rs:WP_025654210	DNA topoisomerase III [Clostridiales bacterium VE202-21].	26.27	552	348	18	7	539	4	515	2e-44	178
rs:WP_041160385	DNA topoisomerase [Peptoclostridium difficile].	26.27	609	393	19	7	604	4	567	2e-44	177
rs:WP_040012585	DNA topoisomerase, partial [Peptostreptococcaceae bacterium CM5].	29.11	505	286	17	7	491	6	458	2e-44	175
rs:WP_023177191	DNA topoisomerase III [Carnobacterium sp. WN1359].	27.34	629	353	25	5	603	3	557	2e-44	178
rs:WP_012419017	DNA topoisomerase III [Bordetella avium].	28.57	574	357	17	5	550	4	552	2e-44	179
tr:L7TZD2_MYXSD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.49	593	342	20	3	531	28	596	2e-44	182
rs:WP_008701761	DNA topoisomerase [Fusobacterium nucleatum].	26.42	579	375	14	7	561	4	555	2e-44	177
rs:WP_035408325	DNA topoisomerase III [Bacillus sp. SJS].	26.56	561	368	15	4	544	1	537	2e-44	178
rs:WP_036866402	DNA topoisomerase III [Prevotella bivia].	27.32	549	348	17	8	531	5	527	2e-44	177
rs:WP_024633998	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	26.70	633	388	21	5	599	3	597	2e-44	179
rs:WP_041890459	DNA topoisomerase I [Myroides profundi].	26.89	569	363	15	4	552	1	536	2e-44	178
rs:WP_026510388	DNA topoisomerase III [Butyrivibrio sp. LC3010].	26.96	612	373	20	5	554	4	603	2e-44	178
rs:WP_038502539	DNA topoisomerase III [Achromobacter xylosoxidans].	29.12	577	350	19	5	550	4	552	2e-44	179
rs:WP_021902623	DNA topoisomerase III [Porphyromonas sp. CAG:1061].	27.79	565	358	17	8	553	5	538	2e-44	177
rs:WP_029044368	DNA topoisomerase III [Cupriavidus sp. WS].	27.46	590	388	17	7	577	6	574	2e-44	179
rs:WP_043375951	DNA topoisomerase III [Comamonas testosteroni].	28.10	605	371	22	5	568	4	585	2e-44	180
rs:WP_020925716	DNA topoisomerase III [Achromobacter xylosoxidans].	29.12	577	350	19	5	550	4	552	2e-44	179
rs:WP_013632693	DNA topoisomerase [Pedobacter saltans].	28.44	552	337	19	4	531	1	518	2e-44	178
rs:WP_043339226	DNA topoisomerase III [Belnapia moabensis].	26.02	565	366	13	7	550	6	539	2e-44	178
rs:WP_017258167	DNA topoisomerase III [Pedobacter arcticus].	27.95	551	347	16	4	531	1	524	2e-44	177
rs:WP_021651108	DNA topoisomerase III [Blautia sp. KLE 1732].	28.42	577	349	21	8	532	7	571	2e-44	178
rs:WP_005827194	DNA topoisomerase III [Bacteroides uniformis].	26.86	566	353	18	7	531	2	547	2e-44	178
rs:WP_002636140	ATP-dependent DNA helicase RecQ [Myxococcus sp. (contaminant ex DSM 436)].	26.75	587	354	17	2	531	24	591	2e-44	181
rs:WP_003060036	DNA topoisomerase III [Comamonas testosteroni].	28.10	605	371	22	5	568	4	585	2e-44	180
rs:WP_006389468	DNA topoisomerase III [Achromobacter xylosoxidans].	29.12	577	350	19	5	550	4	552	2e-44	179
rs:WP_034054058	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	36.01	286	168	5	279	552	17	299	2e-44	174
rs:WP_025074494	DNA topoisomerase III [Bacteroides faecichinchillae].	27.16	556	354	17	7	531	2	537	2e-44	178
rs:WP_009003584	DNA topoisomerase III [Clostridium sp. D5].	27.55	548	335	14	7	532	6	513	2e-44	178
rs:WP_009229127	DNA topoisomerase III [Prevotella sp. oral taxon 317].	28.55	550	333	22	7	531	2	516	2e-44	178
rs:WP_003072146	DNA topoisomerase III [Comamonas testosteroni].	28.10	605	371	22	5	568	4	585	2e-44	180
rs:WP_010188183	conjugal transfer protein TraE [Sphingomonas sp. PAMC 26605].	25.30	577	377	14	1	548	1	552	2e-44	178
rs:WP_027386103	DNA topoisomerase III [Chryseobacterium gregarium].	28.26	545	336	20	8	531	5	515	2e-44	178
rs:WP_034255094	DNA topoisomerase III [Bifidobacterium kashiwanohense].	27.89	631	356	24	7	579	4	593	2e-44	178
rs:WP_006216705	DNA topoisomerase III [Achromobacter piechaudii].	29.29	577	349	19	5	550	4	552	2e-44	179
rs:WP_009667728	DNA topoisomerase III [Oxalobacteraceae bacterium IMCC9480].	28.40	574	359	17	5	550	4	553	2e-44	179
rs:WP_034298270	DNA topoisomerase III [Herbaspirillum sp. RV1423].	28.15	572	366	17	3	550	2	552	2e-44	179
rs:WP_018395842	hypothetical protein [Bacillus sp. 37MA].	27.54	581	361	19	5	555	4	554	2e-44	178
rs:WP_016214645	DNA topoisomerase III [Eubacterium sp. 14-2].	27.27	627	363	22	8	554	7	620	2e-44	178
rs:WP_036861766	DNA topoisomerase III [Prevotella bivia].	27.14	549	349	17	8	531	5	527	2e-44	177
tr:A0A0D6FEB7_ALCXX	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:CKG66100.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CKG66100.1};	28.94	577	351	19	5	550	4	552	2e-44	179
rs:WP_029466987	DNA topoisomerase III [[Clostridium] hathewayi].	26.42	564	353	15	7	549	4	526	2e-44	178
rs:WP_017879692	hypothetical protein [Janthinobacterium sp. CG3].	26.57	572	376	16	7	550	4	559	2e-44	178
rs:WP_010272697	DNA topoisomerase III [Paenibacillus senegalensis].	26.74	647	393	25	7	606	5	617	2e-44	178
rs:WP_035112638	DNA topoisomerase [Finegoldia magna].	26.68	611	388	20	7	604	4	567	2e-44	177
rs:WP_004604812	DNA topoisomerase III [[Clostridium] scindens].	30.14	564	335	18	7	550	4	528	2e-44	177
tr:G9XCL0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.11	505	286	17	7	491	6	458	2e-44	175
rs:WP_023078866	DNA topoisomerase III [Streptococcus pyogenes].	26.94	542	344	15	7	539	4	502	2e-44	176
rs:WP_040381961	DNA topoisomerase III [Clostridiales bacterium 1_7_47FAA].	25.96	570	360	15	1	549	1	529	2e-44	177
rs:WP_041224587	DNA topoisomerase III, partial [Dechloromonas aromatica].	29.43	564	333	22	7	531	6	543	2e-44	179
rs:WP_008823097	DNA topoisomerase III [Prevotella histicola].	28.22	567	336	21	8	531	5	543	2e-44	177
rs:WP_025790876	DNA topoisomerase III [Prevotella histicola].	28.22	567	336	21	8	531	5	543	2e-44	177
rs:WP_027776822	DNA topoisomerase III [Burkholderia caledonica].	27.94	562	368	17	7	550	6	548	2e-44	179
rs:WP_038530696	DNA topoisomerase III [Azospirillum brasilense].	28.55	571	320	21	5	531	3	529	2e-44	178
rs:WP_032212589	DNA topoisomerase III, partial [Escherichia coli].	29.29	420	276	10	101	504	5	419	2e-44	174
rs:WP_014862450	DNA topoisomerase [Enterococcus faecalis].	28.24	556	368	16	5	544	3	543	2e-44	178
rs:WP_016225184	DNA topoisomerase III [Lachnospiraceae bacterium 3-2].	27.26	620	362	21	8	554	7	610	2e-44	177
rs:WP_036628384	DNA topoisomerase III [Oscillospiraceae bacterium VE202-24].	27.59	551	343	17	7	539	5	517	2e-44	177
rs:WP_042177283	DNA topoisomerase III [Paenibacillus sp. FSL R7-0331].	26.46	635	399	18	5	600	3	608	3e-44	178
rs:WP_043004228	DNA topoisomerase III, partial [Vibrio anguillarum].	25.99	504	344	13	116	597	7	503	3e-44	176
rs:WP_041763180	DNA topoisomerase III [Burkholderia phymatum].	27.63	561	371	15	7	550	6	548	3e-44	179
rs:WP_011486439	DNA topoisomerase III [Burkholderia xenovorans].	27.76	562	369	17	7	550	6	548	3e-44	179
rs:WP_034678541	DNA topoisomerase III [Chryseobacterium formosense].	29.09	550	325	22	8	531	5	515	3e-44	177
rs:WP_038493688	DNA topoisomerase III [Collimonas arenae].	28.72	571	365	17	3	550	2	553	3e-44	179
rs:WP_044942468	DNA topoisomerase III [Flavonifractor plautii].	27.86	560	349	19	7	550	4	524	3e-44	177
rs:WP_010781442	DNA topoisomerase III [Enterococcus gilvus].	26.13	551	351	14	7	550	5	506	3e-44	177
rs:WP_024882202	DNA topoisomerase III [Methylosinus sp. LW3].	26.59	613	388	16	5	584	3	586	3e-44	177
tr:B2JJU0_BURP8	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.63	561	371	15	7	550	28	570	3e-44	179
rs:WP_036930306	DNA topoisomerase III [Prevotella sp. 10(H)].	28.14	622	380	24	8	603	5	585	3e-44	177
rs:WP_022042877	DNA topoisomerase III [Bacteroides caccae CAG:21].	27.52	556	353	17	7	531	2	538	3e-44	177
rs:WP_013710309	DNA topoisomerase III [Carnobacterium sp. 17-4].	26.49	555	350	16	5	550	3	508	3e-44	177
tr:G5GKI5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.14	494	305	15	7	491	21	473	3e-44	175
rs:WP_036805062	DNA topoisomerase III [Planomicrobium glaciei].	28.68	551	361	15	7	544	5	536	3e-44	177
rs:WP_021261414	DNA topoisomerase III [Paenibacillus alvei].	26.28	647	396	19	5	603	3	616	3e-44	178
rs:WP_025487928	DNA topoisomerase III [Clostridiales bacterium VE202-27].	26.42	564	353	15	7	549	4	526	3e-44	177
rs:WP_005678837	DNA topoisomerase III [Bacteroides caccae].	27.52	556	353	17	7	531	2	538	3e-44	177
rs:WP_013903096	DNA topoisomerase III [Ramlibacter tataouinensis].	28.60	605	367	24	3	568	2	580	3e-44	180
rs:WP_004276310	DNA topoisomerase III [Campylobacter upsaliensis].	26.46	582	387	17	4	562	1	564	3e-44	177
rs:WP_006464583	DNA topoisomerase III [Herbaspirillum frisingense].	28.20	571	369	16	3	550	2	554	3e-44	179
rs:WP_005682722	DNA topoisomerase III [Bacteroides caccae].	27.52	556	353	17	7	531	2	538	3e-44	177
rs:WP_033626047	DNA topoisomerase [Enterococcus faecalis].	28.42	556	367	16	5	544	3	543	3e-44	177
rs:WP_026526973	DNA topoisomerase III [Butyrivibrio sp. VCD2006].	26.34	615	372	18	5	554	4	602	3e-44	177
rs:WP_034538462	DNA topoisomerase III [Carnobacterium inhibens].	27.34	629	353	25	5	603	3	557	3e-44	177
rs:WP_002571033	MULTISPECIES: DNA topoisomerase III [Lachnoclostridium].	26.26	575	358	16	1	549	1	535	3e-44	177
rs:WP_008372305	MULTISPECIES: DNA topoisomerase III [Coprococcus].	29.21	582	345	23	5	532	4	572	3e-44	177
tr:Q47K54_DECAR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.43	564	333	22	7	531	15	552	3e-44	179
rs:WP_008776282	DNA topoisomerase III [Bacteroides sp. 2_2_4].	26.13	555	361	16	7	531	2	537	3e-44	177
rs:WP_019573873	DNA topoisomerase III [Curvibacter lanceolatus].	28.52	610	367	21	5	568	4	590	3e-44	179
rs:WP_020616278	hypothetical protein [Paenibacillus daejeonensis].	27.54	639	378	23	5	599	3	600	3e-44	178
rs:WP_011000033	DNA topoisomerase III [Ralstonia solanacearum].	27.16	626	406	18	7	606	6	607	3e-44	179
rs:WP_036871357	DNA topoisomerase III [Prevotella histicola].	28.50	572	328	22	8	531	5	543	3e-44	177
rs:WP_009093060	DNA topoisomerase [Elizabethkingia anophelis].	28.30	576	331	19	4	550	1	523	3e-44	177
rs:WP_009246241	MULTISPECIES: DNA topoisomerase III [Lachnospiraceae].	28.02	596	371	20	7	554	6	591	3e-44	177
rs:WP_008978034	DNA topoisomerase III [Erysipelotrichaceae bacterium 5_2_54FAA].	27.03	566	349	15	7	550	6	529	3e-44	177
tr:C5ER81_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.06	564	355	15	7	549	6	528	3e-44	177
tr:D3AGG1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.26	575	358	16	1	549	3	537	3e-44	177
rs:WP_016740752	DNA topoisomerase III [Brevibacillus brevis].	27.01	633	389	21	7	599	5	604	4e-44	177
rs:WP_021563361	hypothetical protein [Escherichia coli].	28.60	563	356	16	7	540	4	549	4e-44	177
rs:WP_022351764	DNA topoisomerase [Firmicutes bacterium CAG:534].	26.34	577	361	19	8	532	7	571	4e-44	177
tr:J8F712_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.50	518	315	18	5	498	4	500	4e-44	175
rs:WP_010763001	DNA topoisomerase III [Enterococcus haemoperoxidus].	27.90	577	321	21	1	550	1	509	4e-44	177
tr:A0A0B5GGH3_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.06	556	369	16	5	544	3	543	4e-44	177
rs:WP_017070755	DNA topoisomerase III, partial [Vibrio crassostreae].	28.51	463	302	12	7	452	5	455	4e-44	174
rs:WP_033560771	DNA topoisomerase III [Escherichia coli].	28.83	562	354	16	8	540	1	545	4e-44	177
rs:WP_002569206	DNA topoisomerase III [[Clostridium] bolteae].	26.42	564	353	15	7	549	4	526	4e-44	177
rs:WP_025815981	DNA topoisomerase III [Prevotella shahii].	28.05	549	337	19	7	531	2	516	4e-44	177
rs:WP_027586242	DNA topoisomerase III [Prolixibacter bellariivorans].	28.54	536	338	16	8	531	5	507	4e-44	177
rs:WP_045487459	DNA topoisomerase III [Bacillus sp. TS-2].	28.67	572	369	18	8	574	8	545	4e-44	177
rs:WP_034122848	DNA topoisomerase III, partial [Peptococcaceae bacterium BICA1-7].	29.32	573	354	20	5	559	3	542	4e-44	177
tr:W2CXK5_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.32	551	357	16	8	539	5	525	4e-44	176
rs:WP_035566908	DNA topoisomerase III [Hymenobacter sp. IS2118].	26.06	568	359	18	4	531	1	547	4e-44	178
rs:WP_016726768	DNA topoisomerase III [Ralstonia solanacearum].	27.59	627	402	20	7	606	6	607	4e-44	179
rs:WP_016722609	DNA topoisomerase III [Ralstonia solanacearum].	27.59	627	402	20	7	606	6	607	4e-44	179
rs:WP_026686798	DNA topoisomerase III [Azovibrio restrictus].	28.08	584	355	22	7	550	6	564	4e-44	178
rs:WP_015396725	DNA topoisomerase III [Candidatus Kinetoplastibacterium oncopeltii].	27.87	567	363	16	7	543	6	556	4e-44	178
rs:WP_028249919	DNA topoisomerase III [Variovorax sp. URHB0020].	28.22	613	368	26	5	568	3	592	4e-44	179
rs:WP_028203227	DNA topoisomerase III [Burkholderia nodosa].	27.63	561	371	15	7	550	6	548	4e-44	179
rs:WP_002339809	DNA topoisomerase III [Enterococcus faecium].	28.24	556	368	16	5	544	3	543	4e-44	177
rs:WP_043307593	DNA topoisomerase III [Burkholderia glumae].	26.39	557	340	14	43	539	27	573	4e-44	177
rs:WP_023872752	MULTISPECIES: DNA topoisomerase III [Pandoraea].	28.38	599	370	21	7	571	6	579	4e-44	179
rs:WP_023598157	DNA topoisomerase III [Pandoraea pnomenusa].	28.38	599	370	21	7	571	6	579	4e-44	179
rs:WP_038012980	DNA topoisomerase III, partial [Terasakiella pusilla].	28.55	557	333	17	5	530	3	525	4e-44	177
rs:WP_032944498	DNA topoisomerase I [Bacteroides vulgatus].	26.16	604	398	17	4	591	1	572	4e-44	177
tr:E3PWY5_CLOSD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.02	523	311	19	56	532	4	517	4e-44	177
rs:WP_010538243	DNA topoisomerase I [Bacteroides faecis].	26.53	603	395	17	4	590	1	571	4e-44	177
tr:S7WTU8_9BACT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EPR70149.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EPR70149.1};	29.90	485	300	14	84	557	10	465	4e-44	177
rs:WP_000765171	DNA topoisomerase III [Escherichia coli].	28.77	563	355	16	7	540	4	549	4e-44	177
tr:A0A097NA41_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.38	599	370	21	7	571	6	579	4e-44	179
rs:WP_044317211	DNA topoisomerase III [Escherichia coli].	28.60	563	356	16	7	540	4	549	4e-44	177
rs:WP_012431376	DNA topoisomerase III [Burkholderia phytofirmans].	27.76	562	369	17	7	550	6	548	4e-44	179
rs:WP_033534309	DNA topoisomerase III [Bordetella trematum].	29.37	555	341	17	5	531	4	535	4e-44	178
rs:WP_024564660	MULTISPECIES: DNA topoisomerase I [Elizabethkingia].	28.52	575	343	19	4	550	1	535	4e-44	177
rs:WP_012816538	DNA topoisomerase III [Staphylococcus aureus].	29.41	561	348	18	5	544	3	536	4e-44	177
rs:WP_025514931	DNA topoisomerase III [Bordetella trematum].	29.37	555	341	17	5	531	4	535	4e-44	178
rs:WP_009220366	DNA topoisomerase III [Lachnospiraceae oral taxon 107].	26.15	608	378	18	7	590	4	564	5e-44	177
rs:WP_008816171	DNA topoisomerase III [Erysipelotrichaceae bacterium 6_1_45].	26.79	560	354	17	7	550	4	523	5e-44	177
rs:WP_005594981	DNA topoisomerase III, partial [Vibrio scophthalmi].	28.78	556	339	17	15	535	2	535	5e-44	177
gp:FP929058_263	DNA topoisomerase III, bacteria and conjugative plasmid [Enterococcus sp. 7L76]	28.24	556	368	16	5	544	3	543	5e-44	177
rs:WP_034212370	DNA topoisomerase III [Lachnoanaerobaculum sp. MSX33].	26.41	640	393	24	8	590	6	624	5e-44	177
rs:WP_019376132	hypothetical protein [Virgibacillus halodenitrificans].	28.10	605	391	20	7	590	4	585	5e-44	177
rs:WP_028363905	DNA topoisomerase III [Burkholderia sp. UYPR1.413].	27.63	561	371	15	7	550	6	548	5e-44	178
tr:X0RBQ7_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.67	572	369	18	8	574	9	546	5e-44	177
rs:WP_007484229	DNA topoisomerase III [Bacteroides nordii].	26.26	556	360	16	7	531	2	538	5e-44	177
rs:WP_000765170	DNA topoisomerase III [Escherichia coli].	29.00	562	353	17	8	540	5	549	5e-44	177
rs:WP_044453283	DNA topoisomerase III [Pandoraea vervacti].	28.38	599	370	21	7	571	6	579	5e-44	178
rs:WP_021773317	DNA topoisomerase [Oribacterium sp. oral taxon 078].	27.42	558	352	19	7	549	4	523	5e-44	177
rs:WP_006485782	DNA topoisomerase III [Burkholderia cenocepacia].	27.58	533	355	13	35	550	10	528	5e-44	178
rs:WP_033624327	DNA topoisomerase III [Enterococcus faecalis].	27.35	563	338	18	1	548	1	507	5e-44	177
rs:WP_003267350	DNA topoisomerase III [Ralstonia solanacearum].	27.04	625	406	18	7	606	6	605	5e-44	178
tr:W7ZEF8_9BACI	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	28.38	511	324	14	3	498	2	485	5e-44	177
rs:WP_006799305	DNA topoisomerase III [Dysgonomonas gadei].	28.28	548	336	18	8	531	5	519	5e-44	177
rs:WP_003021050	DNA topoisomerase III [Blautia hansenii].	27.85	596	372	18	7	554	6	591	5e-44	177
rs:WP_018418959	DNA topoisomerase III [Burkholderia sp. WSM4176].	27.94	562	368	16	7	550	6	548	5e-44	178
rs:WP_003830724	DNA topoisomerase III [Bifidobacterium breve].	26.28	624	375	21	7	579	4	593	5e-44	177
rs:WP_007591669	DNA topoisomerase III [Lachnoanaerobaculum sp. OBRC5-5].	27.40	573	358	20	8	535	6	565	5e-44	176
rs:WP_008333592	DNA topoisomerase III [Herbaspirillum sp. GW103].	28.03	578	361	17	3	550	2	554	5e-44	178
rs:WP_015402308	DNA topoisomerase III [Desulfocapsa sulfexigens].	29.70	596	365	24	1	567	1	571	5e-44	177
rs:WP_021849768	DNA topoisomerase III [Firmicutes bacterium CAG:791].	27.49	582	364	20	7	539	6	578	5e-44	177
rs:WP_040446585	DNA topoisomerase III [Eubacterium ventriosum].	28.47	555	334	18	7	539	4	517	5e-44	177
rs:WP_025866525	DNA topoisomerase III [Bacteroides nordii].	26.26	556	360	16	7	531	2	538	5e-44	177
rs:WP_016273003	DNA topoisomerase III [Bacteroides uniformis].	27.03	566	352	18	7	531	2	547	5e-44	177
rs:WP_010805658	DNA topoisomerase III [Pandoraea sp. SD6-2].	28.48	604	363	23	7	571	6	579	6e-44	178
rs:WP_008650257	DNA topoisomerase III [Bacteroides sp. 3_1_23].	26.13	555	361	16	7	531	2	537	6e-44	177
rs:WP_002667236	DNA topoisomerase III [Capnocytophaga gingivalis].	27.05	562	364	14	40	567	33	582	6e-44	177
rs:WP_015548008	DNA topoisomerase III, bacteria and conjugative plasmid [Alistipes shahii].	26.49	604	396	18	4	591	1	572	6e-44	176
rs:WP_008982916	DNA topoisomerase III [Ruminococcaceae bacterium D16].	26.32	570	358	16	1	549	1	529	6e-44	177
rs:WP_039394586	DNA topoisomerase III [Pandoraea sputorum].	28.38	599	370	21	7	571	6	579	6e-44	178
rs:WP_002997248	transposase [Sphingobacterium spiritivorum].	27.68	560	342	15	4	531	1	529	6e-44	177
rs:WP_039367564	DNA topoisomerase III [Chryseobacterium taiwanense].	29.17	545	331	20	8	531	5	515	6e-44	177
rs:WP_000765167	DNA topoisomerase III [Escherichia coli].	28.60	563	356	16	7	540	4	549	6e-44	177
rs:WP_002569178	MULTISPECIES: DNA topoisomerase III [Firmicutes].	27.03	566	349	15	7	550	6	529	6e-44	176
rs:WP_021538564	hypothetical protein [Escherichia coli].	28.65	562	355	16	8	540	5	549	6e-44	177
rs:WP_007751728	DNA topoisomerase III [Bacteroides finegoldii].	26.90	565	346	18	7	531	2	539	6e-44	176
rs:WP_004611672	hypothetical protein [Tyzzerella nexilis].	25.57	610	383	20	7	590	4	568	6e-44	176
rs:WP_006268790	DNA topoisomerase III [Streptococcus constellatus].	28.73	543	332	19	7	539	4	501	6e-44	175
rs:WP_019638659	DNA topoisomerase III [Paenibacillus fonticola].	26.11	628	394	22	5	599	3	593	6e-44	177
rs:WP_039790282	DNA topoisomerase III, partial [Herbaspirillum huttiense].	28.03	578	361	17	3	550	2	554	6e-44	178
rs:WP_022396805	DNA topoisomerase III [Akkermansia sp. CAG:344].	28.32	579	358	20	3	548	2	556	6e-44	178
rs:WP_013236594	DNA topoisomerase III [Herbaspirillum seropedicae].	28.03	578	361	17	3	550	2	554	6e-44	178
rs:WP_027474744	DNA topoisomerase III [Curvibacter gracilis].	28.52	610	367	21	5	568	4	590	6e-44	179
rs:WP_042266102	DNA topoisomerase III [Burkholderia heleia].	27.45	561	372	15	7	550	6	548	6e-44	178
rs:WP_041753934	DNA topoisomerase III [Burkholderia rhizoxinica].	27.24	580	385	17	7	568	6	566	6e-44	178
rs:WP_034194827	hypothetical protein, partial [Burkholderia sp. WP42].	30.95	349	227	8	8	354	5	341	6e-44	171
rs:WP_041048759	DNA topoisomerase III [Paenibacillus sp. VKM B-2647].	27.10	631	389	20	5	598	3	599	6e-44	177
rs:WP_006162279	DNA topoisomerase III [Cupriavidus basilensis].	27.27	572	360	17	7	550	6	549	6e-44	178
rs:WP_040636960	hypothetical protein, partial [Mucispirillum schaedleri].	28.11	562	359	17	7	539	4	549	6e-44	176
rs:WP_004336120	DNA topoisomerase III [Prevotella bivia].	27.14	549	349	17	8	531	5	527	6e-44	176
rs:WP_009988109	DNA topoisomerase III [Ruminococcus flavefaciens].	27.37	559	347	19	7	552	5	517	6e-44	176
rs:WP_000765168	DNA topoisomerase III [Escherichia coli].	28.65	562	355	16	8	540	5	549	7e-44	176
rs:WP_010731398	DNA topoisomerase III [Enterococcus faecium].	27.88	556	370	16	5	544	3	543	7e-44	176
rs:WP_001401704	DNA topoisomerase III family protein [Escherichia coli].	28.65	562	355	16	8	540	5	549	7e-44	176
rs:WP_035635729	DNA topoisomerase III [Lachnospiraceae bacterium ND2006].	25.27	649	406	23	7	596	6	634	7e-44	176
rs:WP_010105941	DNA topoisomerase III [Verminephrobacter aporrectodeae].	28.36	610	362	25	5	568	4	584	7e-44	179
rs:WP_012247063	DNA topoisomerase III [Bordetella petrii].	28.99	576	356	18	3	550	2	552	7e-44	178
rs:WP_038336868	DNA topoisomerase III [Empedobacter falsenii].	28.12	544	342	18	8	531	5	519	7e-44	176
rs:WP_036655982	DNA topoisomerase III [Paenibacillus wynnii].	26.86	633	394	22	5	599	3	604	7e-44	177
rs:WP_032569384	DNA topoisomerase I [Bacteroides fragilis].	26.66	604	395	18	4	591	1	572	7e-44	176
rs:WP_027865830	DNA topoisomerase III [Massilia alkalitolerans].	29.05	568	357	18	7	550	6	551	7e-44	178
rs:WP_021738124	DNA topoisomerase [Eubacterium ramulus].	27.14	560	352	17	7	550	5	524	7e-44	176
rs:WP_025881445	DNA topoisomerase III [Prevotella baroniae].	28.08	552	340	19	7	531	2	523	7e-44	176
rs:WP_033121899	DNA topoisomerase III [Oscillibacter sp. ER4].	26.96	560	353	17	7	550	4	523	7e-44	176
rs:WP_019937515	DNA topoisomerase III [Bordetella sp. FB-8].	28.01	557	354	16	1	531	1	536	7e-44	178
rs:WP_032572319	DNA topoisomerase I [Bacteroides fragilis].	28.85	565	350	19	4	550	1	531	7e-44	176
rs:WP_008157627	DNA topoisomerase III [Achromobacter arsenitoxydans].	28.94	577	351	19	5	550	4	552	7e-44	178
rs:WP_019004931	hypothetical protein [Cohnella laeviribosi].	26.50	649	387	22	5	599	3	615	7e-44	178
rs:WP_034750284	DNA topoisomerase III [Chryseobacterium vrystaatense].	28.99	545	332	20	8	531	5	515	7e-44	176
rs:WP_013041960	DNA topoisomerase III [Coraliomargarita akajimensis].	28.50	565	352	17	7	539	5	549	7e-44	177
tr:E5AND1_BURRH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.24	580	385	17	7	568	27	587	7e-44	178
rs:WP_043541241	DNA topoisomerase III [Achromobacter sp. RTa].	29.19	555	342	17	5	531	4	535	7e-44	177
rs:WP_044727511	DNA topoisomerase [Streptococcus pneumoniae].	26.19	611	391	19	7	604	4	567	8e-44	175
rs:WP_022479411	DNA topoisomerase III [Prevotella sp. CAG:891].	27.79	565	351	19	7	531	2	549	8e-44	176
rs:WP_003064768	DNA topoisomerase III [Comamonas testosteroni].	27.77	605	373	21	5	568	4	585	8e-44	178
rs:WP_032567317	DNA topoisomerase I [Bacteroides fragilis].	26.66	604	395	18	4	591	1	572	8e-44	176
rs:WP_026626030	DNA topoisomerase III [Dysgonomonas capnocytophagoides].	27.52	545	340	19	8	531	5	515	8e-44	176
rs:WP_002841135	DNA topoisomerase III [Finegoldia magna].	26.35	611	390	20	7	604	4	567	8e-44	175
rs:WP_013544274	DNA topoisomerase III [Variovorax paradoxus].	28.46	615	366	26	5	568	4	595	8e-44	178
tr:H1HW63_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.44	559	327	22	56	555	4	548	8e-44	176
tr:A4MY79_HAEIF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.28	393	236	14	200	563	17	400	8e-44	173
rs:WP_022398796	DNA topoisomerase [Roseburia sp. CAG:471].	27.21	621	366	22	5	553	4	610	8e-44	176
rs:WP_006556993	DNA topoisomerase III [Veillonella ratti].	25.65	612	390	19	8	581	5	589	8e-44	176
rs:WP_025761771	DNA topoisomerase III [Dyadobacter tibetensis].	28.57	539	337	16	8	531	5	510	8e-44	176
rs:WP_013485776	DNA topoisomerase III [Ethanoligenens harbinense].	27.19	548	352	18	7	548	4	510	8e-44	176
rs:WP_006847775	DNA topoisomerase III [Prevotella copri].	27.37	581	331	20	7	531	2	547	8e-44	176
rs:WP_019717336	DNA topoisomerase III [Ralstonia solanacearum].	27.59	627	402	20	7	606	6	607	8e-44	177
tr:G2HD77_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.27	571	367	14	5	539	4	556	8e-44	177
rs:WP_014618279	DNA topoisomerase III [Ralstonia solanacearum].	26.88	625	407	18	7	606	6	605	8e-44	177
rs:WP_044921529	hypothetical protein [Anaerostipes hadrus].	26.62	556	355	19	8	544	7	528	8e-44	176
rs:WP_017249528	DNA topoisomerase III [Brevibacillus brevis].	27.63	637	376	25	5	599	3	596	9e-44	176
rs:WP_039370276	DNA topoisomerase III [Pandoraea pnomenusa].	28.76	605	360	24	7	571	6	579	9e-44	177
tr:G8AN84_AZOBR	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.55	571	320	21	5	531	6	532	9e-44	176
rs:WP_047326379	DNA topoisomerase III [Delftia tsuruhatensis].	27.96	608	371	22	5	568	4	588	9e-44	178
rs:WP_027428651	DNA topoisomerase III [Lachnospiraceae bacterium AD3010].	26.98	556	340	19	7	539	4	516	9e-44	176
rs:WP_025081433	DNA topoisomerase III [Porphyromonas bennonis].	27.09	550	354	15	8	539	5	525	9e-44	176
rs:WP_038592879	DNA topoisomerase III [Paenibacillus sp. FSL H7-0357].	26.14	635	401	18	5	600	3	608	9e-44	176
rs:WP_010750414	DNA topoisomerase III, partial [Enterococcus villorum].	26.93	531	309	18	41	550	1	473	9e-44	176
rs:WP_042590295	DNA topoisomerase III [Ralstonia solanacearum].	26.88	625	407	18	7	606	6	605	9e-44	177
rs:WP_003464782	DNA topoisomerase III [Clostridium perfringens].	29.86	566	342	18	7	550	5	537	9e-44	176
rs:WP_012840372	DNA topoisomerase III [Comamonas testosteroni].	27.77	605	373	21	5	568	4	585	9e-44	178
rs:WP_046424380	DNA topoisomerase III [Escherichia coli].	28.60	563	356	16	7	540	4	549	9e-44	176
rs:WP_016562551	DNA topoisomerase III [Bacteroides sp. CAG:927].	28.25	538	343	17	8	531	3	511	9e-44	176
rs:WP_001687633	DNA topoisomerase III family protein [Escherichia coli].	28.65	562	355	16	8	540	5	549	9e-44	176
rs:WP_028860034	DNA topoisomerase III [Ralstonia solanacearum].	27.16	626	406	18	7	606	6	607	9e-44	177
rs:WP_013207290	DNA topoisomerase III [Ralstonia solanacearum].	26.88	625	407	18	7	606	6	605	9e-44	177
rs:WP_042106000	DNA topoisomerase III [Escherichia coli].	28.60	563	356	16	7	540	4	549	9e-44	176
rs:WP_046460388	DNA topoisomerase III [Comamonas testosteroni].	27.77	605	373	21	5	568	4	585	9e-44	178
rs:WP_016183792	DNA topoisomerase III [Enterococcus columbae].	28.50	572	343	22	7	563	5	525	9e-44	176
rs:WP_034368856	DNA topoisomerase III [Delftia sp. 670].	27.96	608	371	22	5	568	4	588	9e-44	178
rs:WP_001542045	DNA topoisomerase III [Escherichia coli].	28.65	562	355	16	8	540	5	549	9e-44	176
rs:WP_016449409	DNA topoisomerase III [Delftia acidovorans].	27.96	608	371	22	5	568	4	588	9e-44	178
tr:T0U6H2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.56	566	354	19	1	534	206	747	1e-43	176
tr:E2CSK1_9RHOB	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.75	573	353	18	1	546	1	539	1e-43	176
rs:WP_021907748	DNA topoisomerase [Eubacterium sp. CAG:146].	26.61	605	387	20	7	582	5	581	1e-43	176
rs:WP_036928229	DNA topoisomerase III [Prevotella timonensis].	26.99	552	345	19	7	531	2	522	1e-43	175
rs:WP_032274624	DNA topoisomerase III [Escherichia coli].	28.60	563	356	16	7	540	4	549	1e-43	176
rs:WP_023225984	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	28.60	563	356	16	7	540	4	549	1e-43	176
rs:WP_025380732	DNA topoisomerase III [Escherichia coli].	28.60	563	356	16	7	540	4	549	1e-43	176
rs:WP_001631999	DNA topoisomerase III [Staphylococcus aureus].	28.98	559	353	17	5	544	3	536	1e-43	176
rs:WP_034339994	DNA topoisomerase III [Herbaspirillum sp. B39].	28.03	578	361	17	3	550	2	554	1e-43	177
rs:WP_004366086	DNA topoisomerase III [Prevotella nigrescens].	27.14	560	337	19	8	531	5	529	1e-43	175
rs:WP_021434670	DNA topoisomerase III [Peptoclostridium difficile].	28.35	568	340	17	7	550	4	528	1e-43	176
rs:WP_041811868	DNA topoisomerase III [Azospirillum brasilense].	28.55	571	320	21	5	531	3	529	1e-43	176
rs:WP_032249640	DNA topoisomerase III [Escherichia coli].	28.60	563	356	16	7	540	4	549	1e-43	176
rs:WP_033544695	DNA topoisomerase III [Escherichia coli].	28.60	563	356	16	7	540	4	549	1e-43	176
rs:WP_042113879	DNA topoisomerase III [Pandoraea apista].	28.81	604	361	24	7	571	6	579	1e-43	177
rs:WP_042327278	DNA topoisomerase III [Burkholderia ginsengisoli].	27.92	566	363	18	7	550	6	548	1e-43	177
rs:WP_009536236	DNA topoisomerase III [Oribacterium asaccharolyticum].	26.58	602	380	19	7	556	5	596	1e-43	176
rs:WP_025068261	DNA topoisomerase I [Prevotella denticola].	27.17	552	340	16	4	531	2	515	1e-43	176
rs:WP_024813405	DNA topoisomerase III [Acidovorax sp. JHL-3].	27.42	609	373	20	5	568	4	588	1e-43	178
tr:B1XSN4_POLNS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.80	590	380	16	7	568	24	595	1e-43	177
rs:WP_015892060	DNA topoisomerase III [Brevibacillus brevis].	27.49	633	386	22	7	599	5	604	1e-43	176
rs:WP_013744085	DNA topoisomerase III [Pusillimonas sp. T7-7].	26.97	608	397	17	5	592	4	584	1e-43	177
rs:WP_035711184	hypothetical protein, partial [Bacillus aidingensis].	27.52	545	352	15	5	532	3	521	1e-43	176
rs:WP_027324472	DNA topoisomerase III [Bacteroides pyogenes].	26.52	577	353	19	7	531	2	559	1e-43	176
rs:WP_043944901	DNA topoisomerase III [Ralstonia solanacearum].	26.88	625	407	18	7	606	6	605	1e-43	177
rs:WP_044278347	DNA topoisomerase III, partial [Campylobacter jejuni].	26.29	525	346	14	8	512	5	508	1e-43	174
rs:WP_024732370	DNA topoisomerase III [Clostridiales bacterium VE202-14].	28.33	600	359	22	8	554	7	588	1e-43	176
rs:WP_008445093	DNA topoisomerase 3 [Janthinobacterium sp. HH01].	29.07	578	352	21	5	550	4	555	1e-43	177
rs:WP_021426980	DNA topoisomerase III [Peptoclostridium difficile].	28.52	568	339	17	7	550	4	528	1e-43	176
rs:WP_042137824	DNA topoisomerase III [Paenibacillus sp. FSL P4-0081].	26.06	637	399	20	5	600	3	608	1e-43	176
tr:J6YLM5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.01	557	330	23	24	563	2	504	1e-43	176
rs:WP_034054055	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	33.79	293	175	5	276	552	14	303	1e-43	172
rs:WP_020314981	DNA topoisomerase III [Klebsiella pneumoniae].	28.60	563	356	16	7	540	4	549	1e-43	176
rs:WP_000765172	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	28.65	562	355	16	8	540	5	549	1e-43	176
rs:WP_027866328	hypothetical protein [Massilia alkalitolerans].	29.93	578	341	26	5	550	4	549	1e-43	176
rs:WP_024409560	DNA topoisomerase [Streptococcus suis].	26.70	603	390	16	7	599	5	565	1e-43	174
rs:WP_033542386	DNA topoisomerase III [Planococcus sp. CAU13].	29.26	564	349	20	7	548	5	540	1e-43	176
rs:WP_022617840	DNA topoisomerase III; Tn1549-like, CTn4-Orf15 [Peptoclostridium difficile].	28.22	567	342	17	7	550	4	528	1e-43	176
rs:WP_035359824	DNA topoisomerase III [Achromobacter insuavis].	28.77	577	352	19	5	550	4	552	1e-43	177
rs:WP_031906002	DNA topoisomerase III [Staphylococcus aureus].	29.23	561	349	18	5	544	3	536	1e-43	176
rs:WP_017645376	DNA topoisomerase III [Streptococcus agalactiae].	26.10	613	393	19	7	606	4	569	1e-43	174
rs:WP_025699539	DNA topoisomerase III, partial [Paenibacillus durus].	26.47	631	391	21	5	599	3	596	1e-43	175
rs:WP_001420449	DNA topoisomerase III family protein [Escherichia coli].	28.60	563	356	16	7	540	4	549	1e-43	176
rs:WP_031919412	DNA topoisomerase III [Staphylococcus aureus].	29.23	561	349	18	5	544	3	536	1e-43	176
rs:WP_002559428	DNA topoisomerase III [Bacteroides sp. HPS0048].	26.26	556	360	16	7	531	2	538	1e-43	176
rs:WP_007717774	DNA topoisomerase III [Brevibacillus sp. BC25].	27.99	636	383	24	5	599	3	604	1e-43	176
rs:WP_022230861	DNA topoisomerase 3 (DNA topoisomerase III) [Firmicutes bacterium CAG:41].	26.93	583	379	17	7	559	4	569	1e-43	177
rs:WP_037443261	DNA topoisomerase I [Sphingobacterium antarcticum].	28.99	552	334	18	7	531	4	524	1e-43	175
rs:WP_007881181	DNA topoisomerase III [Herbaspirillum sp. CF444].	27.94	569	371	16	3	550	2	552	1e-43	177
rs:WP_044983936	DNA topoisomerase III, partial [Lachnospiraceae bacterium 3_1_57FAA_CT1].	26.98	504	315	13	7	491	4	473	1e-43	173
tr:E0NMC4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.86	611	393	19	7	604	8	571	1e-43	174
rs:WP_043947600	DNA topoisomerase III [Ralstonia solanacearum].	26.88	625	407	18	7	606	6	605	1e-43	177
rs:WP_034965253	DNA topoisomerase III [Epilithonimonas sp. FH1].	28.10	541	340	18	8	531	5	513	1e-43	176
rs:WP_032131993	DNA topoisomerase III [Weeksella sp. FF8].	28.81	538	336	19	8	531	5	509	1e-43	176
rs:WP_002596359	DNA topoisomerase III [[Clostridium] clostridioforme].	26.98	556	341	15	7	539	4	517	1e-43	176
rs:WP_046683462	DNA topoisomerase III [Janthinobacterium sp. KBS0711].	28.05	574	363	18	5	550	4	555	1e-43	177
tr:J6Y259_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.83	557	331	23	24	563	2	504	1e-43	175
rs:WP_006282052	DNA topoisomerase III [Prevotella bryantii].	27.73	559	335	20	7	531	2	525	1e-43	176
rs:WP_034976722	DNA topoisomerase III [Epilithonimonas lactis].	28.10	541	340	18	8	531	5	513	1e-43	176
rs:WP_042577333	DNA topoisomerase III [Variovorax paradoxus].	28.43	619	361	27	5	568	3	594	1e-43	178
rs:WP_034543388	DNA topoisomerase III, partial [Bacteroides pyogenes].	26.47	578	352	19	7	531	2	559	1e-43	175
rs:WP_043679321	DNA topoisomerase III [Castellaniella defragrans].	27.39	566	374	14	5	550	4	552	1e-43	177
rs:WP_024348418	DNA topoisomerase III [[Clostridium] methoxybenzovorans].	27.43	565	345	19	7	550	4	524	1e-43	176
rs:WP_022158033	DNA topoisomerase III [Prevotella sp. CAG:520].	27.85	553	340	17	7	531	2	523	1e-43	175
rs:WP_021589015	DNA topoisomerase III [Prevotella baroniae].	27.90	552	341	19	7	531	2	523	1e-43	175
rs:WP_034749282	DNA topoisomerase III [Janthinobacterium lividum].	28.05	574	363	18	5	550	4	555	1e-43	177
rs:WP_038987553	DNA topoisomerase I [Myroides odoratimimus].	28.02	571	355	19	4	552	1	537	1e-43	175
rs:WP_008125946	DNA topoisomerase III [Prevotella timonensis].	26.99	552	345	19	7	531	2	522	1e-43	175
rs:WP_018574459	hypothetical protein [Oligella ureolytica].	28.88	561	347	16	3	534	2	539	1e-43	177
rs:WP_040551369	DNA topoisomerase [Peptoniphilus duerdenii].	25.86	611	393	19	7	604	4	567	1e-43	174
rs:WP_042474231	hypothetical protein, partial [Bacillus sp. FF3].	28.49	530	325	18	47	553	35	533	1e-43	175
rs:WP_013657846	DNA topoisomerase [Cellulosilyticum lentocellum].	27.02	570	356	17	7	532	5	558	1e-43	176
rs:WP_031878368	DNA topoisomerase III, partial [Staphylococcus aureus].	27.33	505	324	15	7	500	5	477	1e-43	172
rs:WP_026781568	DNA topoisomerase III [Polaromonas sp. EUR3 1.2.1].	27.82	586	364	19	5	550	3	569	2e-43	177
rs:WP_045716821	DNA topoisomerase III, partial [Salmonella enterica].	31.61	348	222	9	217	552	2	345	2e-43	172
tr:A0A061NZC6_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.34	615	401	19	5	606	11	586	2e-43	175
rs:WP_004310571	DNA topoisomerase I [Bacteroides ovatus].	26.49	604	396	18	4	591	1	572	2e-43	175
rs:WP_029194220	DNA topoisomerase III [Paenibacillus alginolyticus].	25.55	638	403	20	5	601	3	609	2e-43	176
rs:WP_028904646	DNA topoisomerase III [Prevotella intermedia].	27.14	560	337	19	8	531	5	529	2e-43	175
rs:WP_020655828	DNA topoisomerase III [Massilia niastensis].	28.95	570	355	20	7	550	6	551	2e-43	177
rs:WP_035824548	DNA topoisomerase III [Janthinobacterium sp. RA13].	28.05	574	363	18	5	550	4	555	2e-43	177
rs:WP_042744647	DNA topoisomerase III, partial [Staphylococcus aureus].	29.23	561	349	18	5	544	3	536	2e-43	174
rs:WP_008982719	DNA topoisomerase III [Ruminococcaceae bacterium D16].	27.14	560	352	17	7	550	4	523	2e-43	175
rs:WP_015914564	DNA topoisomerase III [Acidovorax ebreus].	28.72	592	348	25	5	550	4	567	2e-43	177
rs:WP_012202816	DNA topoisomerase III [Delftia acidovorans].	27.80	608	372	22	5	568	4	588	2e-43	177
rs:WP_002352807	DNA topoisomerase, partial [Enterococcus faecium].	28.60	507	324	16	5	491	3	491	2e-43	173
rs:WP_046226190	DNA topoisomerase III [Paenibacillus dauci].	25.78	574	349	16	7	550	5	531	2e-43	175
rs:WP_039299128	DNA topoisomerase III [Paenibacillus sp. IHB B 3415].	26.06	637	399	20	5	600	3	608	2e-43	176
rs:WP_039198697	DNA topoisomerase III [Bifidobacterium kashiwanohense].	27.20	592	347	22	7	549	4	560	2e-43	175
rs:WP_026696403	hypothetical protein [Bacillus chagannorensis].	27.50	549	371	16	7	544	4	536	2e-43	175
rs:WP_009662480	DNA topoisomerase III [Lachnoanaerobaculum sp. ICM7].	26.95	590	369	20	8	550	6	580	2e-43	175
rs:WP_026640596	DNA topoisomerase III [Bordetella petrii].	28.37	578	357	18	3	550	2	552	2e-43	177
rs:WP_010771366	DNA topoisomerase III [Enterococcus caccae].	26.32	570	339	16	1	550	1	509	2e-43	175
rs:WP_025579750	DNA topoisomerase III [Blautia wexlerae].	28.52	568	339	17	7	550	4	528	2e-43	175
rs:WP_029309062	DNA topoisomerase [Cupriavidus metallidurans].	29.23	585	350	20	7	556	6	561	2e-43	177
rs:WP_028818553	DNA topoisomerase III [beta proteobacterium SCGC AAA027-C02].	27.99	593	379	17	5	568	15	588	2e-43	177
tr:T2NSF2_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.29	555	324	22	28	563	4	503	2e-43	175
rs:WP_010828882	DNA topoisomerase III [Enterococcus faecalis].	27.00	563	340	17	1	548	1	507	2e-43	175
rs:WP_006227776	DNA topoisomerase III [Achromobacter piechaudii].	28.82	576	353	18	5	550	4	552	2e-43	177
tr:W2C565_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.40	553	354	17	8	539	5	525	2e-43	174
rs:WP_027633415	hypothetical protein [Clostridium hydrogeniformans].	26.71	599	371	21	1	573	11	567	2e-43	175
tr:W1K7D6_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.15	543	327	17	26	550	3	489	2e-43	175
rs:WP_011979365	DNA topoisomerase III [Janthinobacterium sp. Marseille].	28.77	570	362	19	5	550	4	553	2e-43	177
rs:WP_034389805	DNA topoisomerase III [Delftia acidovorans].	27.80	608	372	22	5	568	4	588	2e-43	177
rs:WP_035236464	ATP-dependent DNA helicase RecQ, partial [Acidobacteriaceae bacterium URHE0068].	28.67	593	355	20	5	552	17	586	2e-43	176
rs:WP_007766830	DNA topoisomerase III [Bacteroides finegoldii].	26.90	565	346	18	7	531	2	539	2e-43	175
tr:W8A717_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.08	527	334	17	5	509	3	506	2e-43	173
rs:WP_021539434	hypothetical protein [Escherichia coli].	27.23	573	365	15	8	544	5	561	2e-43	175
rs:WP_000002937	DNA topoisomerase [Streptococcus agalactiae].	29.38	497	300	16	53	539	1	456	2e-43	173
rs:WP_014710026	DNA topoisomerase III [Prevotella intermedia].	27.14	560	337	19	8	531	5	529	2e-43	174
rs:WP_038011289	DNA topoisomerase III, partial [Tannerella sp. oral taxon BU063].	26.22	553	355	17	8	539	5	525	2e-43	174
tr:A0A0D3LDW1_9BACT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AHM60286.1};	28.78	549	332	20	7	531	2	515	2e-43	175
rs:WP_009263227	DNA topoisomerase III [Lachnospiraceae bacterium 9_1_43BFAA].	27.27	594	349	22	7	566	4	548	2e-43	175
rs:WP_036889711	DNA topoisomerase I [Porphyromonas crevioricanis].	27.02	570	354	16	5	552	3	532	2e-43	175
tr:V2RK58_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESJ98103.1};	28.11	562	359	17	7	539	4	549	2e-43	176
rs:WP_032586196	DNA topoisomerase I [Bacteroides fragilis].	26.87	603	385	17	4	592	1	561	2e-43	175
rs:WP_025000225	DNA topoisomerase III [Prevotella aurantiaca].	27.14	560	337	19	8	531	5	529	2e-43	174
rs:WP_019131012	DNA topoisomerase I [Bacteroidales bacterium ph8].	26.87	603	385	17	4	592	1	561	2e-43	175
rs:WP_041729228	DNA topoisomerase III, partial [Desulfovibrio vulgaris].	25.72	591	375	15	3	548	2	573	2e-43	175
rs:WP_015713669	DNA topoisomerase III [Bifidobacterium longum].	27.39	628	363	23	7	579	4	593	2e-43	175
rs:WP_042795811	DNA topoisomerase III [Achromobacter xylosoxidans].	28.88	554	345	16	5	531	4	535	2e-43	176
rs:WP_032538771	DNA topoisomerase, partial [Peptoclostridium difficile].	27.67	506	317	15	43	539	13	478	2e-43	173
rs:WP_002561001	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	26.87	603	385	17	4	592	1	561	2e-43	175
tr:W7WFC9_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.33	600	377	20	7	568	6	584	2e-43	174
tr:C9AEQ4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.40	507	336	12	72	563	1	495	2e-43	175
rs:WP_000859496	DNA topoisomerase III [Staphylococcus aureus].	29.23	561	349	18	5	544	3	536	2e-43	175
rs:WP_003264700	DNA topoisomerase III [Ralstonia solanacearum].	26.88	625	407	18	7	606	6	605	2e-43	176
rs:WP_036613668	DNA topoisomerase III [Paenibacillus sp. FSL H7-689].	26.50	634	390	21	5	599	3	599	2e-43	175
rs:WP_025491675	DNA topoisomerase III, partial [Clostridiales bacterium VE202-27].	27.00	526	330	14	43	549	5	495	2e-43	174
rs:WP_001235764	DNA topoisomerase III [Escherichia coli].	28.83	562	354	17	8	540	5	549	2e-43	175
tr:C9BBV7_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.40	507	336	12	72	563	1	495	2e-43	174
rs:WP_036872645	DNA topoisomerase III [Prevotella buccalis].	27.49	553	341	21	7	531	2	522	2e-43	174
tr:F7KHC2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.98	504	315	13	7	491	4	473	2e-43	172
rs:WP_040349721	DNA topoisomerase [Anaerococcus tetradius].	25.86	611	393	19	7	604	4	567	2e-43	174
rs:WP_046803989	DNA topoisomerase III [Achromobacter sp. LC458].	28.82	576	353	18	5	550	4	552	2e-43	176
rs:WP_024835747	DNA topoisomerase III [Clostridium sp. 12(A)].	26.05	618	371	23	8	554	7	609	2e-43	175
rs:WP_025698624	DNA topoisomerase III, partial [Paenibacillus durus].	27.88	477	305	13	7	472	5	453	2e-43	172
rs:WP_013804570	DNA topoisomerase III [Delftia sp. Cs1-4].	27.80	608	372	22	5	568	4	588	2e-43	177
rs:WP_019879542	hypothetical protein [Succinispira mobilis].	27.52	596	388	17	7	579	5	579	2e-43	175
rs:WP_014081130	DNA topoisomerase III [Roseburia hominis].	26.98	556	341	15	7	539	4	517	2e-43	175
rs:WP_026435498	DNA topoisomerase III [Acidovorax sp. JHL-9].	27.50	611	366	22	5	568	4	584	2e-43	177
rs:WP_041397274	DNA topoisomerase III [Polynucleobacter necessarius].	27.63	590	381	16	7	568	1	572	2e-43	176
rs:WP_033448977	DNA topoisomerase III [Bordetella bronchiseptica].	28.92	574	355	19	5	550	4	552	2e-43	176
rs:WP_002321930	DNA topoisomerase III [Enterococcus faecium].	28.01	557	330	23	24	563	2	504	2e-43	174
rs:WP_034784739	DNA topoisomerase III [Janthinobacterium lividum].	28.05	574	363	18	5	550	4	555	2e-43	176
rs:WP_002594223	DNA topoisomerase III [[Clostridium] clostridioforme].	27.45	612	369	21	7	590	4	568	2e-43	175
tr:C0AQN2_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.12	415	264	13	8	409	5	406	2e-43	171
rs:WP_032587146	DNA topoisomerase I [Bacteroides fragilis].	26.61	605	395	18	4	591	1	573	2e-43	174
tr:G5GKN4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.74	515	296	16	45	539	3	466	2e-43	173
rs:WP_038574535	DNA topoisomerase III [Paenibacillus odorifer].	26.37	637	397	21	5	600	3	608	2e-43	175
rs:WP_024990781	DNA topoisomerase I [Prevotella marshii].	26.87	603	385	17	4	592	1	561	2e-43	174
tr:J6WLB4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.83	557	331	22	24	563	2	504	3e-43	174
rs:WP_016222100	DNA topoisomerase III [Dorea sp. 5-2].	27.31	553	342	17	7	539	5	517	3e-43	174
rs:WP_043825380	DNA topoisomerase III [Delftia sp. RIT313].	27.80	608	372	22	5	568	4	588	3e-43	177
rs:WP_036673825	DNA topoisomerase III [Paenibacillus sp. FSL R5-192].	26.50	634	390	21	5	599	3	599	3e-43	175
rs:WP_031867296	DNA topoisomerase III [Staphylococcus aureus].	29.06	561	350	18	5	544	3	536	3e-43	174
rs:WP_023056591	MULTISPECIES: DNA topoisomerase III [Prevotella].	27.49	553	341	21	7	531	2	522	3e-43	174
rs:WP_034439060	DNA topoisomerase [Candidatus Clostridium anorexicamassiliense].	28.12	569	358	19	5	548	3	545	3e-43	174
rs:WP_000765166	DNA topoisomerase III [Escherichia coli].	28.60	563	356	16	7	540	4	549	3e-43	175
rs:WP_015057151	DNA topoisomerase III [Escherichia coli].	28.60	563	356	16	7	540	4	549	3e-43	175
rs:WP_021361815	DNA topoisomerase III [Peptoclostridium difficile].	28.04	567	343	17	7	550	4	528	3e-43	174
rs:WP_033471215	DNA topoisomerase III [Bordetella bronchiseptica].	28.75	574	356	18	5	550	4	552	3e-43	176
rs:WP_025844504	DNA topoisomerase III, partial [Paenibacillus ehimensis].	26.32	623	392	19	5	590	3	595	3e-43	174
rs:WP_013389292	DNA topoisomerase III [Ilyobacter polytropus].	27.65	604	367	22	7	589	4	558	3e-43	174
tr:W4PUM3_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE22789.1};	26.47	578	352	19	7	531	17	574	3e-43	175
rs:WP_032537012	MULTISPECIES: DNA topoisomerase III [Bacteroides].	26.62	556	358	15	7	531	2	538	3e-43	174
tr:W4PIV4_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE19069.1};	26.52	577	353	19	7	531	71	628	3e-43	176
tr:V6V9G4_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.47	475	288	17	4	456	1	450	3e-43	171
rs:WP_003831767	DNA topoisomerase III [Bifidobacterium breve].	27.39	628	363	23	7	579	4	593	3e-43	175
tr:E0NQU0_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFM02460.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFM02460.1};	26.82	604	386	17	3	592	19	580	3e-43	174
rs:WP_031906444	DNA topoisomerase III [Staphylococcus aureus].	28.98	559	353	17	5	544	3	536	3e-43	174
tr:R2LGJ5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.33	540	318	22	41	563	1	488	3e-43	174
rs:WP_036590367	DNA topoisomerase III, partial [Paenibacillus sophorae].	26.73	565	353	18	5	539	3	536	3e-43	174
rs:WP_035109583	DNA topoisomerase [Finegoldia magna].	25.86	611	393	19	7	604	4	567	3e-43	173
tr:E4IH74_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.01	557	330	23	24	563	2	504	3e-43	174
rs:WP_014248119	DNA topoisomerase III [Azospirillum lipoferum].	27.62	572	331	17	5	531	3	536	3e-43	175
rs:WP_028353834	DNA topoisomerase III [Bordetella petrii].	28.82	576	357	18	3	550	2	552	3e-43	176
rs:WP_018989244	DNA topoisomerase III [Azoarcus toluclasticus].	28.47	576	353	22	7	550	6	554	3e-43	176
rs:WP_021113548	DNA topoisomerase III family protein, partial [Haemophilus parasuis].	30.25	400	250	12	8	391	5	391	3e-43	170
rs:WP_016833774	DNA topoisomerase III [Herbaspirillum lusitanum].	28.15	572	366	18	3	550	2	552	3e-43	176
tr:S4EWF5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.01	557	330	23	24	563	2	504	3e-43	174
tr:A0A098EIM9_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.80	552	359	15	7	544	5	536	3e-43	174
rs:WP_039121402	DNA topoisomerase [Fusobacterium necrophorum].	25.99	608	396	20	7	604	4	567	3e-43	173
rs:WP_021537783	hypothetical protein [Escherichia coli].	28.60	563	356	16	7	540	4	549	3e-43	174
rs:WP_014430656	DNA topoisomerase III [Rubrivivax gelatinosus].	28.45	608	362	24	5	567	4	583	3e-43	176
rs:WP_032537565	DNA topoisomerase III [Bacteroides fragilis].	26.62	556	358	15	7	531	2	538	3e-43	174
rs:WP_005781365	DNA topoisomerase III [Bacteroides fragilis].	26.62	556	358	15	7	531	2	538	3e-43	174
rs:WP_022429476	DNA topoisomerase III [Prevotella stercorea CAG:629].	28.26	552	338	18	7	531	2	522	3e-43	174
tr:S4DV85_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.01	557	330	23	24	563	2	504	3e-43	174
rs:WP_026823973	DNA topoisomerase III [Arsenophonus nasoniae].	27.44	554	367	15	8	539	5	545	3e-43	174
rs:WP_021824923	DNA topoisomerase [Prevotella salivae].	26.93	635	384	19	4	595	1	598	3e-43	174
tr:A0A024FL16_9FLAO	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.31	542	357	16	15	550	2	512	3e-43	174
rs:WP_012816503	DNA topoisomerase III [Staphylococcus aureus].	28.98	559	353	17	5	544	3	536	3e-43	174
rs:WP_026287158	hypothetical protein [Gilvimarinus chinensis].	27.38	577	367	14	1	544	1	558	3e-43	174
rs:WP_022474363	DNA topoisomerase III [Ruminococcus sp. CAG:353].	27.63	608	364	20	7	588	7	564	3e-43	175
rs:WP_008957431	DNA topoisomerase III [Halomonas sp. HAL1].	27.99	593	360	21	1	546	1	573	3e-43	175
rs:WP_042128274	DNA topoisomerase III [Paenibacillus sp. FSL R5-0345].	26.22	637	398	20	5	600	3	608	3e-43	175
rs:WP_019117236	DNA topoisomerase III [Anaerococcus sp. PH9].	26.35	611	390	20	7	604	4	567	3e-43	173
rs:WP_010820938	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	3e-43	174
rs:WP_039972867	DNA topoisomerase III [Bacteroides pyogenes].	26.30	578	353	19	7	531	2	559	3e-43	175
rs:WP_046228621	DNA topoisomerase III [Paenibacillus algorifonticola].	27.02	581	338	20	7	550	5	536	3e-43	174
tr:A0A099I8C9_CLOIN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	25.73	548	356	16	17	550	2	512	3e-43	174
rs:WP_031874414	DNA topoisomerase III [Staphylococcus aureus].	28.98	559	353	17	5	544	3	536	3e-43	174
rs:WP_012290743	DNA topoisomerase III [Finegoldia magna].	25.86	611	393	19	7	604	4	567	3e-43	173
rs:WP_015040782	DNA topoisomerase iii [Bordetella parapertussis].	28.57	574	357	18	5	550	4	552	3e-43	176
rs:WP_025073101	DNA topoisomerase III [Prevotella timonensis].	26.99	552	345	19	7	531	2	522	3e-43	174
rs:WP_044201455	DNA topoisomerase III [Flammeovirga sp. OC4].	27.06	547	341	17	8	531	5	516	3e-43	175
rs:WP_005366709	DNA topoisomerase III [[Eubacterium] yurii].	28.00	550	331	20	7	539	4	505	3e-43	173
tr:D6SB76_FINMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.86	611	393	19	7	604	8	571	3e-43	173
rs:WP_033466984	DNA topoisomerase III [Bordetella bronchiseptica].	28.88	554	345	16	5	531	4	535	3e-43	176
rs:WP_042853333	DNA topoisomerase III [Staphylococcus aureus].	29.23	561	349	18	5	544	3	536	3e-43	174
rs:WP_017644362	DNA topoisomerase III [Streptococcus agalactiae].	25.86	611	393	19	7	604	4	567	3e-43	173
rs:WP_024300313	DNA topoisomerase [Methylosarcina lacus].	28.15	540	346	17	4	531	1	510	3e-43	174
rs:WP_031864418	DNA topoisomerase III [Staphylococcus aureus].	28.98	559	353	17	5	544	3	536	4e-43	174
tr:J6LFB8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.01	557	330	23	24	563	2	504	4e-43	174
rs:WP_046213924	DNA topoisomerase III [Paenibacillus wulumuqiensis].	26.50	566	344	14	7	544	5	526	4e-43	174
rs:WP_026835960	DNA topoisomerase III [Eubacterium xylanophilum].	27.73	642	388	27	8	590	7	631	4e-43	174
tr:K1G861_BACFG	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKA90429.1};	26.62	556	358	15	7	531	26	562	4e-43	174
rs:WP_034169408	DNA topoisomerase III [Escherichia coli].	28.60	563	356	16	7	540	4	549	4e-43	174
rs:WP_039328218	DNA topoisomerase I [Myroides sp. A21].	26.71	569	364	15	4	552	1	536	4e-43	174
rs:WP_038496368	DNA topoisomerase III [Janthinobacterium agaricidamnosum].	28.77	577	355	20	5	550	4	555	4e-43	176
rs:WP_033452845	DNA topoisomerase III [Bordetella bronchiseptica].	28.57	574	357	18	5	550	4	552	4e-43	175
tr:C2CIB3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.86	611	393	19	7	604	8	571	4e-43	173
rs:WP_019968966	DNA topoisomerase I [Prevotella maculosa].	27.55	559	360	17	4	543	1	533	4e-43	174
tr:K1FRK7_BACFG	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKA80127.1};	26.62	556	358	15	7	531	26	562	4e-43	174
rs:WP_013597426	DNA topoisomerase III [Weeksella virosa].	29.15	542	329	20	8	531	5	509	4e-43	174
rs:WP_003815970	DNA topoisomerase III [Bordetella bronchiseptica].	28.57	574	357	18	5	550	4	552	4e-43	176
rs:WP_043400217	ATP-dependent DNA helicase RecQ [Cystobacter violaceus].	25.34	588	371	18	7	547	4	570	4e-43	177
tr:U2CVP4_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERI88620.1};	26.30	578	353	19	7	531	18	575	4e-43	175
rs:WP_021503224	DNA topoisomerase III family protein [Escherichia coli].	28.47	562	356	16	8	540	5	549	4e-43	174
rs:WP_035523344	DNA topoisomerase III [Burkholderia sacchari].	27.09	561	374	15	7	550	6	548	4e-43	176
rs:WP_033469647	DNA topoisomerase III [Bordetella bronchiseptica].	28.57	574	357	18	5	550	4	552	4e-43	176
rs:WP_021848434	DNA topoisomerase III [Bacteroides sp. CAG:598].	26.32	570	355	18	7	531	2	551	4e-43	174
rs:WP_021388935	DNA topoisomerase, partial [Peptoclostridium difficile].	28.12	569	340	18	7	550	4	528	4e-43	172
rs:WP_036081149	DNA topoisomerase III [Lysinibacillus boronitolerans].	27.56	566	351	19	7	544	6	540	4e-43	174
rs:WP_033592006	DNA topoisomerase III [Enterococcus faecalis].	27.35	563	338	18	1	548	1	507	4e-43	174
rs:WP_033657898	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	4e-43	174
rs:WP_016462896	DNA topoisomerase III [Bifidobacterium breve].	26.20	561	360	13	7	539	4	538	4e-43	174
rs:WP_045147076	DNA topoisomerase III [Escherichia coli].	28.60	563	356	16	7	540	4	549	4e-43	174
sp:TOP1_BACPE	RecName: Full=DNA topoisomerase 1; EC=5.99.1.2; AltName: Full=DNA topoisomerase I; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	26.60	594	396	16	7	581	4	576	4e-43	174
rs:WP_031864845	DNA topoisomerase III [Staphylococcus aureus].	29.23	561	349	18	5	544	3	536	4e-43	174
rs:WP_022833319	DNA topoisomerase III [Cytophagales bacterium B6].	27.99	561	350	18	4	539	1	532	4e-43	173
tr:R3I7T2_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.15	540	319	22	41	563	1	488	4e-43	174
rs:WP_000779865	DNA topoisomerase III [Streptococcus agalactiae].	26.35	611	390	20	7	604	4	567	4e-43	173
tr:I3Z129_BELBD	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.36	550	341	18	4	531	1	519	4e-43	173
rs:WP_017688080	DNA topoisomerase III [Paenibacillus sp. PAMC 26794].	26.34	634	391	20	5	599	3	599	4e-43	174
tr:S4G1Y5_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.78	558	330	19	7	548	63	563	4e-43	174
rs:WP_024998619	DNA topoisomerase III [Prevotella falsenii].	27.27	561	335	20	8	531	5	529	4e-43	173
rs:WP_010929817	DNA topoisomerase III [Bordetella pertussis].	28.57	574	357	18	5	550	4	552	4e-43	176
rs:WP_003818222	DNA topoisomerase iii [Bordetella bronchiseptica].	28.57	574	357	18	5	550	4	552	4e-43	175
rs:WP_042997783	DNA topoisomerase III [Bordetella bronchiseptica].	28.57	574	357	18	5	550	4	552	4e-43	175
rs:WP_032594406	DNA topoisomerase I [Bacteroides fragilis].	26.52	607	393	21	4	591	1	573	4e-43	174
tr:E6FP47_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.60	558	331	19	7	548	63	563	4e-43	174
rs:WP_021580495	hypothetical protein [Escherichia coli].	28.42	563	357	16	7	540	4	549	4e-43	174
rs:WP_025478548	DNA topoisomerase III, partial [Enterococcus faecium].	27.96	540	320	22	41	563	1	488	5e-43	174
rs:WP_019053936	conjugal transfer protein TraE [Sphingobium xenophagum].	25.87	576	375	15	1	548	1	552	5e-43	174
rs:WP_038930464	DNA topoisomerase III, partial [Yersinia pestis].	30.16	378	239	9	170	531	32	400	5e-43	172
tr:U6RS94_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOA58661.1};	26.76	568	354	19	7	531	20	568	5e-43	174
rs:WP_033450699	DNA topoisomerase III [Bordetella bronchiseptica].	28.57	574	357	18	5	550	4	552	5e-43	175
rs:WP_006058367	DNA topoisomerase III [Holdemania filiformis].	27.14	560	352	16	7	550	5	524	5e-43	174
rs:WP_002372058	DNA topoisomerase III [Enterococcus faecalis].	27.29	557	334	18	7	548	7	507	5e-43	174
rs:WP_016278636	DNA topoisomerase III [Bacteroides massiliensis].	26.36	569	368	18	4	552	1	538	5e-43	174
rs:WP_046723272	DNA topoisomerase III [Paenibacillus durus].	26.47	631	391	21	5	599	3	596	5e-43	175
rs:WP_011810900	DNA topoisomerase III [Verminephrobacter eiseniae].	27.52	625	357	25	5	568	4	593	5e-43	176
rs:WP_023353350	DNA topoisomerase III [Catonella morbi].	25.99	608	379	18	7	590	4	564	5e-43	174
rs:WP_042692623	DNA topoisomerase III, partial [Azospirillum sp. B506].	27.48	524	327	14	43	531	1	506	5e-43	172
rs:WP_033458597	DNA topoisomerase III [Bordetella bronchiseptica].	28.57	574	357	18	5	550	4	552	5e-43	175
rs:WP_035854511	DNA topoisomerase III [Dechloromonas agitata].	28.67	572	335	22	7	535	6	547	5e-43	175
rs:WP_025692666	DNA topoisomerase III [Paenibacillus zanthoxyli].	26.06	637	386	23	5	599	3	596	5e-43	174
tr:S0RWA0_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.52	528	315	16	41	550	1	473	5e-43	174
rs:WP_043701074	DNA topoisomerase III, partial [Tepidimonas taiwanensis].	27.86	621	365	23	5	568	7	601	5e-43	175
rs:WP_009961403	DNA topoisomerase III [Verrucomicrobium spinosum].	28.99	576	337	23	3	531	2	552	5e-43	175
rs:WP_033839942	DNA topoisomerase III [Bordetella bronchiseptica].	28.57	574	357	18	5	550	4	552	5e-43	175
rs:WP_009520705	MULTISPECIES: DNA topoisomerase III [Hydrogenophaga].	28.53	617	359	26	5	567	3	591	5e-43	176
rs:WP_022780297	DNA topoisomerase III [Lachnospiraceae bacterium NK4A136].	26.90	617	370	23	7	554	6	610	5e-43	174
rs:WP_017814627	DNA topoisomerase III [Paenibacillus sp. A9].	25.78	574	349	16	7	550	5	531	5e-43	174
rs:WP_033027589	DNA topoisomerase III, partial [Geobacillus sp. MAS1].	29.64	469	283	17	4	450	1	444	5e-43	171
rs:WP_034549119	DNA topoisomerase III [Carnobacterium alterfunditum].	25.90	610	386	19	5	603	3	557	5e-43	174
rs:WP_033467544	DNA topoisomerase III [Bordetella bronchiseptica].	28.57	574	357	18	5	550	4	552	5e-43	175
rs:WP_044707711	DNA topoisomerase III, partial [Escherichia coli].	31.61	348	222	9	217	552	1	344	5e-43	171
rs:WP_033626659	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	5e-43	174
rs:WP_018451999	DNA topoisomerase III [Bacteroides massiliensis].	26.76	568	354	19	7	531	2	550	5e-43	174
rs:WP_041779466	DNA topoisomerase I, partial [Belliella baltica].	28.36	550	341	18	4	531	1	519	5e-43	172
rs:WP_032569262	DNA topoisomerase I [Bacteroides fragilis].	26.49	604	396	18	4	591	1	572	5e-43	174
rs:WP_009430769	DNA topoisomerase III [Peptoniphilus sp. oral taxon 375].	25.94	609	395	19	7	604	4	567	5e-43	172
rs:WP_015389938	DNA topoisomerase III [Kinetoplastibacterium blastocrithidii].	27.91	559	354	17	7	540	6	540	5e-43	175
rs:WP_015042051	DNA topoisomerase iii [Bordetella bronchiseptica].	28.57	574	357	18	5	550	4	552	5e-43	175
rs:WP_010929538	MULTISPECIES: DNA topoisomerase III [Bordetella].	28.57	574	357	18	5	550	4	552	5e-43	175
rs:WP_008617926	DNA topoisomerase I [Paraprevotella clara].	27.76	562	347	16	4	543	1	525	5e-43	174
rs:WP_015237730	DNA topoisomerase III [Kinetoplastibacterium blastocrithidii].	27.91	559	354	17	7	540	6	540	5e-43	174
rs:WP_010730827	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	5e-43	174
rs:WP_039451807	DNA topoisomerase I [Pedobacter glucosidilyticus].	28.16	554	336	18	7	531	4	524	5e-43	173
rs:WP_042742432	DNA topoisomerase III [Staphylococcus aureus].	29.23	561	349	18	5	544	3	536	5e-43	174
rs:WP_004350923	DNA topoisomerase III [Prevotella buccalis].	27.49	553	341	21	7	531	2	522	5e-43	173
tr:E0GCU2_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.60	558	331	19	7	548	63	563	5e-43	174
rs:WP_025341761	DNA topoisomerase III [Bifidobacterium breve].	26.20	561	360	13	7	539	4	538	6e-43	174
rs:WP_031925419	DNA topoisomerase III [Staphylococcus aureus].	28.98	559	353	17	5	544	3	536	6e-43	174
rs:WP_027158454	DNA topoisomerase [Methylobacter luteus].	28.12	537	348	17	4	531	1	508	6e-43	174
tr:E0H3Y9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.60	558	331	19	7	548	63	563	6e-43	174
rs:WP_009130680	DNA topoisomerase III [Bacteroides oleiciplenus].	26.86	566	352	20	7	531	2	546	6e-43	174
rs:WP_021861155	DNA topoisomerase III [Dorea sp. CAG:105].	27.26	598	374	18	8	553	7	595	6e-43	173
rs:WP_010731992	DNA topoisomerase III [Enterococcus faecium].	27.96	540	320	22	41	563	1	488	6e-43	173
rs:WP_018108421	DNA topoisomerase III [Bacteroides propionicifaciens].	27.73	541	342	18	7	531	2	509	6e-43	173
rs:WP_000779864	DNA topoisomerase III [Streptococcus agalactiae].	26.19	611	391	20	7	604	4	567	6e-43	172
rs:WP_022506815	DNA topoisomerase III [Bacteroides sp. CAG:98].	26.76	568	354	19	7	531	20	568	6e-43	174
rs:WP_004338303	MULTISPECIES: DNA topoisomerase I [Prevotella].	27.36	552	339	16	4	531	2	515	6e-43	173
tr:C9ANH7_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.40	507	336	12	72	563	1	495	6e-43	173
rs:WP_036745280	hypothetical protein, partial [Peptoclostridium difficile].	26.20	561	371	13	7	544	4	544	6e-43	173
rs:WP_032562869	DNA topoisomerase I [Bacteroides fragilis].	26.46	616	390	20	4	591	1	581	6e-43	174
rs:WP_002359812	DNA topoisomerase, partial [Enterococcus faecium].	28.51	505	323	16	5	489	3	489	6e-43	171
rs:WP_016306102	hypothetical protein [Lachnospiraceae bacterium A2].	27.15	641	356	24	8	550	7	634	6e-43	174
tr:K1RRE4_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC46094.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EKC46094.1};	28.26	552	339	16	7	539	4	517	6e-43	173
rs:WP_010815836	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	6e-43	173
rs:WP_018579558	MULTISPECIES: DNA topoisomerase III [Firmicutes].	28.18	543	334	16	7	539	4	500	6e-43	172
tr:L2R6Q6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.15	540	319	22	41	563	1	488	6e-43	173
rs:WP_003610064	DNA topoisomerase III [Methylosinus trichosporium].	26.49	619	379	19	5	584	3	584	6e-43	173
rs:WP_007173335	DNA topoisomerase I [Prevotella bergensis].	27.62	554	335	17	4	531	2	515	6e-43	173
rs:WP_033656229	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	6e-43	173
rs:WP_005878079	DNA topoisomerase III [Oxalobacter formigenes].	28.52	596	372	23	5	571	4	574	6e-43	175
rs:WP_000779863	DNA topoisomerase III [Streptococcus agalactiae].	26.10	613	393	20	7	606	4	569	6e-43	172
rs:WP_002363152	DNA topoisomerase, partial [Enterococcus faecium].	28.51	505	323	16	5	489	3	489	6e-43	171
rs:WP_044722401	DNA topoisomerase III [Escherichia coli].	28.01	614	393	19	7	590	4	598	7e-43	173
tr:C3DWF6_BACTS	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEM37751.1};	27.57	573	372	17	50	601	1	551	7e-43	173
rs:WP_035637696	DNA topoisomerase III [Lachnospiraceae bacterium ND2006].	27.89	563	335	20	7	539	4	525	7e-43	173
tr:E6ILE0_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.60	558	331	19	7	548	63	563	7e-43	174
rs:WP_033656182	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	7e-43	173
tr:L2MPF4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.15	540	319	22	41	563	1	488	7e-43	173
rs:WP_013583068	DNA topoisomerase [Yersinia pestis].	27.08	565	366	15	8	544	5	551	7e-43	173
rs:WP_004334692	DNA topoisomerase III [Porphyromonas endodontalis].	26.90	632	386	22	7	602	2	593	7e-43	172
rs:WP_000259053	DNA topoisomerase III [Streptococcus agalactiae].	26.98	619	383	21	4	602	2	571	7e-43	172
rs:WP_044271898	DNA topoisomerase I [Candidatus Bacteroides timonensis].	26.70	543	351	14	7	531	4	517	7e-43	173
rs:WP_033456757	DNA topoisomerase III [Bordetella bronchiseptica].	28.57	574	357	18	5	550	4	552	7e-43	175
rs:WP_007895910	DNA topoisomerase III [Streptococcus pseudoporcinus].	26.94	542	344	16	7	539	4	502	7e-43	172
rs:WP_008642133	DNA topoisomerase III [Cupriavidus sp. HMR-1].	26.39	557	340	14	43	539	27	573	7e-43	173
tr:J9H4U6_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJX11118.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EJX11118.1};	27.40	573	344	21	7	531	50	598	7e-43	174
rs:WP_022498679	DNA topoisomerase [Firmicutes bacterium CAG:95].	25.60	582	367	16	8	532	7	579	7e-43	173
rs:WP_002362072	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	7e-43	173
rs:WP_034820674	DNA topoisomerase, partial [[Eubacterium] nodatum].	29.03	503	307	17	5	498	3	464	7e-43	171
rs:WP_043816567	DNA topoisomerase III [Rubrivivax gelatinosus].	28.29	608	363	24	5	567	4	583	8e-43	174
rs:WP_036892672	DNA topoisomerase III [Prevotella sp. S7-1-8].	27.75	555	338	18	7	531	2	523	8e-43	173
rs:WP_031838445	DNA topoisomerase III, partial [Staphylococcus aureus].	28.11	466	297	13	107	559	1	441	8e-43	172
rs:WP_010818429	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	8e-43	173
rs:WP_010773489	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	8e-43	173
rs:WP_028121874	DNA topoisomerase III [Epilithonimonas tenax].	28.47	541	338	18	8	531	5	513	8e-43	173
rs:WP_045147099	DNA topoisomerase III [Peptoclostridium difficile].	26.32	585	367	16	3	563	2	546	8e-43	173
rs:WP_016203107	DNA topoisomerase [Bacillus nealsonii].	26.94	605	399	17	7	590	4	586	8e-43	173
rs:WP_032825815	DNA topoisomerase III, partial [Haemophilus haemolyticus].	30.25	433	260	17	7	413	4	420	8e-43	169
rs:WP_042744581	topoisomerase I, partial [Oenococcus oeni].	31.21	503	305	19	5	486	3	485	8e-43	171
rs:WP_010764183	DNA topoisomerase III [Enterococcus moraviensis].	27.10	572	332	19	1	550	1	509	8e-43	173
rs:WP_033659502	MULTISPECIES: DNA topoisomerase III [Enterococcus].	27.29	557	334	18	7	548	7	507	8e-43	173
rs:WP_004346383	DNA topoisomerase I [Prevotella buccae].	27.98	554	329	19	7	531	5	517	8e-43	173
tr:E6HHC9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.60	558	331	19	7	548	63	563	8e-43	173
rs:WP_038704916	DNA topoisomerase III [Planococcus sp. PAMC 21323].	29.24	554	354	17	7	544	5	536	8e-43	173
rs:WP_033591694	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	8e-43	173
tr:W7WFD4_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.33	600	377	20	7	568	6	584	8e-43	174
rs:WP_017812425	hypothetical protein [Paenibacillus sp. A9].	26.39	629	392	23	7	599	5	598	8e-43	174
tr:R4BFE2_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.15	540	319	22	41	563	1	488	8e-43	173
rs:WP_036915603	DNA topoisomerase III, partial [Prevotella sp. P6B4].	27.56	566	331	21	7	531	2	529	8e-43	172
rs:WP_006256849	DNA topoisomerase [Myroides odoratimimus].	26.54	569	365	15	4	552	1	536	8e-43	173
rs:WP_032285169	DNA topoisomerase III [Escherichia coli].	28.01	614	393	19	7	590	4	598	8e-43	173
tr:G0F0R0_CUPNN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.84	534	328	17	46	550	5	515	8e-43	174
tr:A0A059MY33_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.29	557	334	18	7	548	63	563	8e-43	173
rs:WP_025577250	DNA topoisomerase III [Blautia wexlerae].	26.87	603	351	22	8	532	7	597	8e-43	173
rs:WP_029730844	DNA topoisomerase III [Dorea sp. AGR2135].	26.82	563	354	19	7	550	6	529	8e-43	173
rs:WP_031902829	DNA topoisomerase III [Staphylococcus aureus].	29.06	561	350	18	5	544	3	536	8e-43	173
tr:E6ICX1_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.42	558	332	19	7	548	63	563	8e-43	173
tr:L8A5I9_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.15	540	319	22	41	563	1	488	8e-43	173
rs:WP_033625995	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	8e-43	173
tr:E2ZLR8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.02	533	326	17	40	550	18	509	8e-43	173
tr:F9GLD9_HAEHA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.34	435	261	17	7	415	4	422	8e-43	170
rs:WP_020229248	DNA topoisomerase III [Acidovorax sp. MR-S7].	27.93	605	371	21	5	568	4	584	8e-43	175
rs:WP_006427278	DNA topoisomerase III [Dorea longicatena].	26.62	601	378	18	8	554	7	598	8e-43	173
tr:G4L3K7_TETHN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.06	556	369	16	5	544	3	543	8e-43	172
rs:WP_043350930	DNA topoisomerase III [Cupriavidus basilensis].	27.12	590	390	17	7	577	6	574	8e-43	175
rs:WP_042161815	DNA topoisomerase III [Paenibacillus sp. G1].	26.29	639	399	19	5	600	3	612	8e-43	174
rs:WP_042236846	DNA topoisomerase III [Paenibacillus sp. FSL R5-0912].	25.90	637	400	20	5	600	3	608	8e-43	173
tr:R4EG70_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.15	540	319	22	41	563	1	488	8e-43	173
rs:WP_044704774	DNA topoisomerase III [Escherichia coli].	28.60	563	356	17	7	540	4	549	8e-43	173
rs:WP_016648539	DNA topoisomerase III [Facklamia hominis].	26.02	611	392	20	7	604	4	567	9e-43	172
rs:WP_002838480	DNA topoisomerase III [Finegoldia magna].	27.49	542	341	16	7	539	4	502	9e-43	172
rs:WP_022621591	DNA topoisomerase III; Tn1549-like, CTn4-Orf15 [Peptoclostridium difficile].	28.40	567	341	17	7	550	4	528	9e-43	173
rs:WP_037986700	DNA topoisomerase III, partial [Tannerella sp. oral taxon BU063].	26.36	550	355	17	8	539	5	522	9e-43	172
rs:WP_007895001	DNA topoisomerase III [Streptococcus pseudoporcinus].	26.94	542	344	16	7	539	4	502	9e-43	172
tr:A0A091CID4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.15	540	319	22	41	563	1	488	9e-43	173
rs:WP_002330030	DNA topoisomerase III, partial [Enterococcus faecium].	28.15	540	319	22	41	563	1	488	9e-43	173
rs:WP_036695438	DNA topoisomerase III [Paenibacillus sp. FSL R7-269].	26.22	637	398	21	5	600	3	608	9e-43	173
tr:R2NIZ1_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.15	540	319	22	41	563	1	488	9e-43	172
tr:D4QJS4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.15	540	319	22	41	563	1	488	9e-43	172
rs:WP_021419783	DNA topoisomerase III [Peptoclostridium difficile].	28.57	567	340	17	7	550	4	528	9e-43	173
tr:S4FHU0_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.60	558	331	19	7	548	63	563	9e-43	173
rs:WP_022252283	DNA topoisomerase III [Prevotella sp. CAG:386].	27.40	573	334	20	7	531	2	540	9e-43	173
tr:A0A073BI74_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.15	540	319	22	41	563	1	488	9e-43	172
rs:WP_004351990	DNA topoisomerase I [Prevotella denticola].	27.09	561	360	16	4	543	1	533	9e-43	173
rs:WP_002366910	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	9e-43	173
tr:W3Z2X6_9FUSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.29	555	350	19	7	550	4	521	9e-43	173
rs:WP_022163221	DNA topoisomerase III [Bacteroides sp. CAG:633].	26.89	569	352	20	7	531	2	550	9e-43	173
tr:E6FJ07_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.29	557	334	18	7	548	63	563	9e-43	173
tr:S4EN54_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.29	557	334	18	7	548	63	563	9e-43	173
rs:WP_033660098	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	9e-43	173
rs:WP_002381707	DNA topoisomerase III [Enterococcus faecalis].	27.48	564	336	19	1	548	1	507	9e-43	173
rs:WP_032463650	DNA topoisomerase III [Streptococcus pyogenes].	25.94	609	395	18	7	604	4	567	9e-43	172
rs:WP_047199848	DNA topoisomerase [Streptococcus agalactiae].	26.14	612	394	20	7	606	4	569	9e-43	172
rs:WP_004349950	DNA topoisomerase I [Prevotella buccalis].	27.39	555	335	18	4	531	2	515	9e-43	173
rs:WP_002992175	MULTISPECIES: DNA topoisomerase [Myroides].	26.54	569	365	15	4	552	1	536	9e-43	173
rs:WP_018357839	DNA topoisomerase I [Porphyromonas levii].	27.27	572	353	17	4	552	2	533	9e-43	173
rs:WP_037582686	DNA topoisomerase [Streptococcus anginosus].	28.02	496	308	14	53	539	1	456	9e-43	171
rs:WP_027016978	DNA topoisomerase III [Comamonas composti].	29.17	593	344	26	5	550	4	567	9e-43	175
rs:WP_009345214	DNA topoisomerase III [Peptoniphilus sp. oral taxon 836].	26.23	610	392	21	7	604	4	567	1e-42	172
rs:WP_015059543	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	28.01	614	393	19	7	590	4	598	1e-42	173
rs:WP_018910666	DNA topoisomerase I [Prevotella veroralis].	27.17	552	340	17	4	531	2	515	1e-42	173
rs:WP_022223423	DNA topoisomerase III [Clostridium sp. CAG:253].	27.23	683	389	28	3	603	2	658	1e-42	173
rs:WP_002388224	DNA topoisomerase III [Enterococcus faecalis].	27.29	557	334	18	7	548	7	507	1e-42	173
rs:WP_007173277	DNA topoisomerase I [Prevotella bergensis].	26.63	552	343	16	4	531	2	515	1e-42	173
rs:WP_031897507	DNA topoisomerase III, partial [Staphylococcus aureus].	28.11	466	297	13	107	559	17	457	1e-42	172
tr:Q099E1_STIAD	SubName: Full=Topoisomerase B {ECO:0000313|EMBL:EAU68374.1};	25.93	590	354	19	2	531	28	594	1e-42	176
rs:WP_036687820	DNA topoisomerase III [Paenibacillus sp. FSL H8-237].	26.37	637	397	21	5	600	3	608	1e-42	173
tr:W4BTV7_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.37	637	397	21	5	600	5	610	1e-42	173
rs:WP_026747454	DNA topoisomerase [Leptotrichia trevisanii].	28.78	556	340	19	7	548	5	518	1e-42	173
rs:WP_005800963	DNA topoisomerase I [Bacteroides fragilis].	28.10	580	343	21	4	552	1	537	1e-42	173
rs:WP_044555099	DNA topoisomerase [Streptococcus pyogenes].	26.02	611	392	20	7	604	4	567	1e-42	172
rs:WP_009080346	DNA topoisomerase, partial [Peptostreptococcaceae bacterium AS15].	28.54	508	303	18	7	498	4	467	1e-42	170
rs:WP_046151725	DNA topoisomerase I [Parabacteroides sp. HGS0025].	27.11	557	357	14	7	543	4	531	1e-42	173
rs:WP_009336444	hypothetical protein, partial [Bacillus sp. 2_A_57_CT2].	26.79	504	330	14	7	489	6	491	1e-42	171
rs:WP_036790611	DNA topoisomerase I [Porphyromonas canoris].	26.08	579	353	16	5	552	3	537	1e-42	173
rs:WP_014079867	DNA topoisomerase [Roseburia hominis].	26.58	617	366	22	7	554	6	604	1e-42	176
rs:WP_006954185	DNA topoisomerase III [Sphingobium japonicum].	25.87	576	375	15	1	548	1	552	1e-42	173
rs:WP_032840587	DNA topoisomerase [Fusobacterium sp. CM21].	28.29	555	350	19	7	550	8	525	1e-42	173
rs:WP_027951620	DNA topoisomerase III [Hallella seregens].	27.45	561	332	20	7	531	2	523	1e-42	173
rs:WP_007902515	DNA topoisomerase III [Prevotella stercorea].	27.78	558	339	18	7	531	2	528	1e-42	173
rs:WP_022354483	DNA topoisomerase III [Bacteroides sp. CAG:875].	27.35	574	335	19	7	531	2	542	1e-42	173
rs:WP_021904993	DNA topoisomerase III [Clostridium sp. CAG:81].	26.68	611	368	21	7	550	6	603	1e-42	172
rs:WP_021424740	DNA topoisomerase [Peptoclostridium difficile].	29.47	543	332	20	5	533	3	508	1e-42	173
rs:WP_004381796	DNA topoisomerase III [Prevotella veroralis].	27.64	568	331	20	8	531	5	536	1e-42	172
rs:WP_002340969	DNA topoisomerase III, partial [Enterococcus faecium].	27.78	540	321	22	41	563	1	488	1e-42	172
rs:WP_000779862	DNA topoisomerase III [Streptococcus pneumoniae].	26.15	608	395	19	7	604	4	567	1e-42	172
rs:WP_016195967	DNA topoisomerase III [Arcticibacter svalbardensis].	27.93	555	342	17	4	531	1	524	1e-42	173
rs:WP_023958691	DNA topoisomerase III [Paenibacillus sp. JCM 10914].	26.87	629	392	21	5	599	3	597	1e-42	173
rs:WP_018910169	DNA topoisomerase III [Prevotella veroralis].	27.69	567	332	20	8	531	5	536	1e-42	172
rs:WP_013378047	ATP-dependent DNA helicase RecQ [Stigmatella aurantiaca].	25.93	590	354	19	2	531	23	589	1e-42	176
rs:WP_011861108	DNA topoisomerase III [Peptoclostridium difficile].	28.04	567	343	17	7	550	4	528	1e-42	172
rs:WP_010710575	DNA topoisomerase III [Enterococcus faecalis].	27.29	557	334	18	7	548	7	507	1e-42	172
rs:WP_034552912	DNA topoisomerase III [Carnobacterium funditum].	25.72	556	353	16	5	550	3	508	1e-42	172
rs:WP_004362216	DNA topoisomerase III [Prevotella nigrescens].	26.79	560	339	19	8	531	5	529	1e-42	172
rs:WP_010708822	DNA topoisomerase III [Enterococcus faecalis].	27.00	563	340	18	1	548	1	507	1e-42	172
rs:WP_036880331	DNA topoisomerase I [Prevotella buccalis].	25.21	603	405	15	4	591	1	572	1e-42	172
rs:WP_041655760	DNA topoisomerase III [Azoarcus sp. KH32C].	28.09	559	356	18	7	539	6	544	1e-42	174
rs:WP_019976661	hypothetical protein [Empedobacter brevis].	28.15	547	338	20	8	531	5	519	1e-42	173
tr:F2MQ93_ENTFO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.60	558	331	19	7	548	63	563	1e-42	173
rs:WP_033627478	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	1e-42	172
rs:WP_044111880	hypothetical protein [Porphyromonas uenonis].	28.65	576	340	20	1	544	1	537	1e-42	172
tr:S4BBF3_ENTCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.49	553	331	20	28	563	4	503	1e-42	172
rs:WP_036797036	hypothetical protein, partial [Leisingera caerulea].	25.70	607	375	17	1	557	1	581	1e-42	172
rs:WP_027109670	DNA topoisomerase III [Lachnospiraceae bacterium NC2008].	26.30	616	375	21	7	554	6	610	1e-42	172
rs:WP_025831777	DNA topoisomerase III [Bacteroides stercorirosoris].	26.90	565	353	19	7	531	2	546	1e-42	173
rs:WP_032542968	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	25.21	603	405	15	4	591	1	572	1e-42	172
rs:WP_023059450	DNA topoisomerase III [Peptoniphilus sp. BV3AC2].	25.86	611	393	19	7	604	4	567	1e-42	171
rs:WP_046226540	DNA topoisomerase III [Paenibacillus dauci].	26.23	629	393	23	7	599	5	598	1e-42	173
gpu:CP011509_1477	DNA topoisomerase III [Archangium gephyra]	25.34	592	374	18	3	547	8	578	1e-42	176
rs:WP_033524055	DNA topoisomerase III [Bifidobacterium pseudocatenulatum].	26.58	632	363	24	7	579	4	593	1e-42	173
rs:WP_006255415	DNA topoisomerase I [Alloprevotella tannerae].	26.57	572	358	17	4	552	2	534	1e-42	172
rs:WP_005817457	DNA topoisomerase III [Bacteroides fragilis].	26.50	566	346	18	7	531	2	538	1e-42	172
rs:WP_032561755	DNA topoisomerase III [Bacteroides fragilis].	26.50	566	346	18	7	531	2	538	1e-42	172
rs:WP_036894906	DNA topoisomerase I [Prevotella sp. S7-1-8].	26.86	551	343	16	4	531	2	515	1e-42	172
rs:WP_006801223	DNA topoisomerase I [Dysgonomonas gadei].	27.23	573	366	17	7	558	4	546	1e-42	172
rs:WP_031613135	DNA topoisomerase III, partial [Salmonella enterica].	31.69	344	219	9	221	552	1	340	1e-42	169
rs:WP_038146532	DNA topoisomerase III [Verrucomicrobia bacterium SCGC AAA027-I19].	29.28	567	348	19	7	536	6	556	1e-42	174
rs:WP_007056103	DNA topoisomerase III [Bifidobacterium longum].	26.47	563	356	14	7	539	4	538	1e-42	172
rs:WP_033148685	DNA topoisomerase III, partial [Prevotella sp. P6B1].	27.56	566	331	21	7	531	2	529	1e-42	172
rs:WP_008790355	MULTISPECIES: hypothetical protein [Coprobacillus].	29.25	588	366	24	34	601	40	597	1e-42	172
rs:WP_022021451	DNA topoisomerase III [Bacteroides sp. CAG:661].	26.14	570	356	18	7	531	2	551	1e-42	172
rs:WP_022267008	DNA topoisomerase [Firmicutes bacterium CAG:449].	29.60	544	314	22	34	544	7	514	1e-42	172
rs:WP_023557382	DNA topoisomerase III [Brevibacillus panacihumi].	26.55	629	393	22	5	599	3	596	1e-42	173
rs:WP_017877597	DNA topoisomerase III [Janthinobacterium sp. CG3].	28.05	574	363	18	5	550	4	555	1e-42	174
rs:WP_039873735	DNA topoisomerase III [Paenibacillus sp. FSL R7-0273].	25.98	635	402	18	5	600	3	608	1e-42	173
rs:WP_036726462	DNA topoisomerase III [Paenibacillus sp. FSL R7-277].	26.14	635	401	19	5	600	3	608	1e-42	173
rs:WP_014219927	DNA topoisomerase III [Niastella koreensis].	28.89	540	335	17	8	531	5	511	1e-42	172
rs:WP_032734795	DNA topoisomerase III, partial [Bifidobacterium breve].	26.90	632	361	25	7	579	4	593	1e-42	173
rs:WP_033600878	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	1e-42	172
rs:WP_033626788	DNA topoisomerase III [Enterococcus faecalis].	27.35	563	338	18	1	548	1	507	1e-42	172
tr:S4D4N9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.93	555	326	22	28	563	4	503	1e-42	172
rs:WP_021747342	MULTISPECIES: DNA topoisomerase III [Oscillibacter].	26.96	560	353	17	7	550	4	523	1e-42	172
rs:WP_040015752	DNA topoisomerase III, partial [Dorea formicigenerans].	27.06	510	319	13	1	491	1	476	1e-42	170
tr:E2YTF1_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.42	558	332	19	7	548	63	563	1e-42	173
rs:WP_013666865	DNA topoisomerase [Sphingobacterium sp. 21].	28.17	575	349	20	4	552	1	537	1e-42	172
rs:WP_035314731	DNA topoisomerase III [Brochothrix campestris].	26.73	565	374	16	7	559	5	541	1e-42	172
rs:WP_010715326	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	1e-42	172
rs:WP_036165815	DNA topoisomerase III [Lysinibacillus sphaericus].	28.62	573	352	21	5	548	3	547	1e-42	172
tr:H0PYH2_9RHOO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.09	559	356	18	7	539	15	553	1e-42	174
rs:WP_002380452	DNA topoisomerase III [Enterococcus faecalis].	27.00	563	340	18	1	548	1	507	1e-42	172
rs:WP_019036208	MULTISPECIES: DNA topoisomerase I [Prevotella].	27.17	552	340	16	4	531	2	515	1e-42	172
rs:WP_006044967	DNA topoisomerase III [Prevotella pallens].	26.05	641	382	23	8	603	5	598	1e-42	172
rs:WP_047351249	DNA topoisomerase III, partial [Diaphorobacter sp. J5-51].	28.11	587	358	22	5	550	4	567	1e-42	174
rs:WP_035070810	DNA topoisomerase III, partial [Desulfovibrio termitidis].	25.47	581	366	14	5	537	4	565	1e-42	173
rs:WP_015298395	DNA topoisomerase III [Prevotella dentalis].	27.45	561	332	20	7	531	2	523	1e-42	172
rs:WP_010080729	DNA topoisomerase III [Bifidobacterium longum].	26.20	561	360	14	7	539	4	538	1e-42	172
rs:WP_032533840	DNA topoisomerase III [Bacteroides fragilis].	26.50	566	346	18	7	531	2	538	1e-42	172
rs:WP_006859375	DNA topoisomerase III [Roseburia intestinalis].	28.42	563	326	21	7	539	4	519	1e-42	172
rs:WP_010777799	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	1e-42	172
tr:Q1J4U0_STRPF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.02	611	392	20	7	604	8	571	2e-42	171
rs:WP_002374513	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	2e-42	172
rs:WP_020491229	hypothetical protein [Dehalobacter sp. FTH1].	28.24	556	346	19	7	548	4	520	2e-42	172
rs:WP_010826160	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	2e-42	172
rs:WP_015844258	DNA topoisomerase III [Paenibacillus sp. JDR-2].	27.21	577	340	16	5	539	3	541	2e-42	173
rs:WP_004611958	DNA topoisomerase III [Tyzzerella nexilis].	26.92	561	352	16	7	550	4	523	2e-42	172
rs:WP_002378482	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	2e-42	172
rs:WP_014546643	DNA topoisomerase III [Fibrobacter succinogenes].	27.27	561	375	19	5	550	34	576	2e-42	174
rs:WP_027641614	DNA topoisomerase III [[Clostridium] clostridioforme].	26.44	590	358	23	8	532	7	585	2e-42	172
rs:WP_021640983	DNA topoisomerase III [[Clostridium] symbiosum].	26.09	594	355	22	8	532	7	585	2e-42	172
rs:WP_004377587	DNA topoisomerase I [Prevotella oris].	27.40	551	340	16	4	531	2	515	2e-42	172
rs:WP_021361579	DNA topoisomerase III [Peptoclostridium difficile].	27.64	568	344	17	7	550	4	528	2e-42	172
rs:WP_033591622	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	2e-42	172
rs:WP_031909847	DNA topoisomerase III, partial [Staphylococcus aureus].	30.18	507	321	16	5	499	3	488	2e-42	170
rs:WP_010993481	DNA topoisomerase III [Bacteroides fragilis].	26.63	567	344	19	7	531	2	538	2e-42	172
rs:WP_002369154	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	2e-42	172
rs:WP_032573824	DNA topoisomerase III [Bacteroides fragilis].	26.63	567	344	19	7	531	2	538	2e-42	172
rs:WP_002356968	DNA topoisomerase III [Enterococcus faecalis].	27.18	563	339	18	1	548	1	507	2e-42	172
tr:U6S1R1_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.29	557	334	18	7	548	63	563	2e-42	172
rs:WP_003510596	MULTISPECIES: DNA topoisomerase III [Clostridiales].	26.09	594	355	22	8	532	7	585	2e-42	172
rs:WP_000419478	hypothetical protein, partial [Salmonella enterica].	36.50	274	159	6	278	539	57	327	2e-42	169
tr:T4NA99_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.20	561	371	13	7	544	4	544	2e-42	172
rs:WP_005790880	DNA topoisomerase III [Bacteroides fragilis].	26.50	566	346	18	7	531	2	538	2e-42	172
rs:WP_010823795	DNA topoisomerase III [Enterococcus faecalis].	27.74	566	332	20	1	548	1	507	2e-42	172
rs:WP_033611595	DNA topoisomerase, partial [Enterococcus faecium].	26.87	562	345	17	5	539	3	525	2e-42	172
rs:WP_044947806	DNA topoisomerase III [Blautia schinkii].	26.90	606	370	22	8	554	7	598	2e-42	172
rs:WP_032567764	DNA topoisomerase I [Bacteroides fragilis].	25.21	603	405	15	4	591	1	572	2e-42	172
tr:S2ZM87_BIFBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EPD75485.1};	27.06	632	360	25	7	579	4	593	2e-42	173
rs:WP_035275918	DNA topoisomerase III [Desulfobulbus japonicus].	27.13	586	385	21	5	567	4	570	2e-42	173
tr:E6GNJ7_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.29	557	334	18	7	548	63	563	2e-42	172
rs:WP_008769960	DNA topoisomerase III [Bacteroides sp. 2_1_16].	26.63	567	344	19	7	531	2	538	2e-42	172
rs:WP_032529132	DNA topoisomerase III [Bacteroides fragilis].	26.63	567	344	19	7	531	2	538	2e-42	172
rs:WP_022295803	DNA topoisomerase [Firmicutes bacterium CAG:272].	28.75	574	350	18	7	551	4	547	2e-42	172
rs:WP_046331014	DNA topoisomerase III [Polynucleobacter necessarius].	26.95	616	401	18	7	590	24	622	2e-42	174
tr:W2BXL6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.03	503	307	17	5	498	3	464	2e-42	171
rs:WP_000779868	DNA topoisomerase III [Streptococcus agalactiae].	26.51	611	389	20	7	604	4	567	2e-42	171
rs:WP_005825426	DNA topoisomerase I [Bacteroides uniformis].	26.70	543	351	14	7	531	4	517	2e-42	172
tr:D4ELR4_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.60	558	331	19	7	548	63	563	2e-42	172
rs:WP_042188790	DNA topoisomerase III [Paenibacillus sp. FSL H7-0737].	26.22	637	398	21	5	600	3	608	2e-42	172
tr:F9D0D7_PREDD	SubName: Full=DNA topoisomerase TopB {ECO:0000313|EMBL:EGQ16953.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EGQ16953.1};	27.45	561	332	20	7	531	37	558	2e-42	172
rs:WP_042214434	DNA topoisomerase III [Paenibacillus borealis].	25.75	637	401	20	5	600	3	608	2e-42	172
rs:WP_032590617	DNA topoisomerase III [Bacteroides fragilis].	26.63	567	344	19	7	531	2	538	2e-42	172
rs:WP_039931025	DNA topoisomerase [Anaerococcus lactolyticus].	26.75	542	345	16	7	539	4	502	2e-42	171
rs:WP_005609809	DNA topoisomerase III [Ruminococcus lactaris].	26.67	615	363	21	8	550	7	605	2e-42	172
rs:WP_006739580	DNA topoisomerase [Streptococcus urinalis].	27.86	542	333	19	4	530	2	500	2e-42	171
rs:WP_034255044	DNA topoisomerase III [Bifidobacterium kashiwanohense].	26.20	561	360	15	7	539	4	538	2e-42	172
tr:B0GA94_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.06	510	319	13	1	491	1	476	2e-42	170
rs:WP_037476926	DNA topoisomerase III [Sphaerotilus natans].	27.79	601	378	23	3	567	2	582	2e-42	174
rs:WP_044567173	DNA topoisomerase [Anaerococcus sp. 9402080].	26.35	611	390	20	7	604	4	567	2e-42	171
rs:WP_039913594	DNA topoisomerase [Anaerococcus hydrogenalis].	25.62	609	397	19	7	604	4	567	2e-42	171
tr:C9B5N6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.60	507	335	13	72	563	1	495	2e-42	172
rs:WP_024807736	topoisomerase I [Verrucomicrobia bacterium LP2A].	27.22	551	361	15	5	531	4	538	2e-42	173
rs:WP_022348346	MULTISPECIES: DNA topoisomerase III [Bacteroides].	26.63	567	344	19	7	531	2	538	2e-42	172
rs:WP_002996062	MULTISPECIES: DNA topoisomerase [Bacteroidetes].	27.36	625	378	19	4	592	1	585	2e-42	172
rs:WP_041929814	DNA topoisomerase III [Methylibium petroleiphilum].	27.33	600	377	20	7	568	6	584	2e-42	173
gpu:CP009928_787	DNA topoisomerase I [Chryseobacterium gallinarum]	28.47	555	334	19	4	531	1	519	2e-42	172
rs:WP_011807073	DNA topoisomerase III [Acidovorax sp. JS42].	28.11	587	358	22	5	550	4	567	2e-42	174
rs:WP_014235929	DNA topoisomerase III [Azospira oryzae].	29.28	567	343	20	7	540	6	547	2e-42	173
rs:WP_019138735	DNA topoisomerase [Peptoniphilus timonensis].	26.19	611	391	20	7	604	4	567	2e-42	171
rs:WP_010726543	DNA topoisomerase III [Enterococcus faecium].	26.87	562	345	17	5	539	3	525	2e-42	172
rs:WP_029103745	hypothetical protein [Moraxella caprae].	26.39	576	375	18	7	548	4	564	2e-42	172
rs:WP_021870156	DNA topoisomerase [Clostridium sp. CAG:7].	25.67	596	363	20	8	535	7	590	2e-42	172
rs:WP_005798157	DNA topoisomerase III [Bacteroides fragilis].	26.50	566	346	18	7	531	2	538	2e-42	172
rs:WP_028899761	DNA topoisomerase I [Prevotella sp. HJM029].	27.19	559	362	15	4	543	1	533	2e-42	172
rs:WP_009905259	DNA topoisomerase III [Peptoclostridium difficile].	28.04	567	343	17	7	550	4	528	2e-42	172
rs:WP_009983779	DNA topoisomerase III [Ruminococcus flavefaciens].	27.37	559	347	19	7	552	5	517	2e-42	172
rs:WP_004026788	DNA topoisomerase III [Ureaplasma urealyticum].	26.11	609	394	19	7	604	4	567	2e-42	171
rs:WP_022527651	toprim domain protein [Bifidobacterium longum].	26.02	561	361	14	7	539	4	538	2e-42	172
rs:WP_032563483	DNA topoisomerase III [Bacteroides fragilis].	26.63	567	344	19	7	531	2	538	2e-42	172
rs:WP_005802239	DNA topoisomerase III [Bacteroides fragilis].	26.63	567	344	19	7	531	2	538	2e-42	172
rs:WP_009534223	DNA topoisomerase III [Oribacterium parvum].	26.25	602	382	19	7	556	5	596	2e-42	171
tr:D3LED0_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.15	540	319	22	41	563	1	488	2e-42	171
rs:WP_000237217	DNA topoisomerase III [Streptococcus oralis].	27.01	559	355	15	4	550	2	519	2e-42	171
rs:WP_032565346	DNA topoisomerase III [Bacteroides fragilis].	26.28	567	346	18	7	531	2	538	2e-42	172
rs:WP_010825356	DNA topoisomerase III [Enterococcus faecalis].	27.29	557	334	18	7	548	7	507	2e-42	172
rs:WP_036757769	DNA topoisomerase [Peptoniphilus lacrimalis].	26.94	542	344	16	7	539	4	502	2e-42	171
rs:WP_004907636	hypothetical protein [Acinetobacter junii].	29.91	565	344	20	7	542	5	546	2e-42	172
tr:L2JGT7_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.15	540	319	22	41	563	1	488	2e-42	171
rs:WP_028548283	DNA topoisomerase III [Paenibacillus sp. UNC451MF].	27.35	618	387	18	5	590	3	590	2e-42	172
rs:WP_023945960	DNA topoisomerase III [Helicobacter fennelliae].	24.62	589	385	15	8	563	5	567	2e-42	171
rs:WP_032593454	DNA topoisomerase III [Bacteroides fragilis].	26.63	567	344	19	7	531	2	538	2e-42	172
rs:WP_046710691	ATP-dependent DNA helicase RecQ [Myxococcus fulvus].	26.22	595	349	20	2	531	22	591	2e-42	175
tr:B6W693_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.62	609	397	19	7	604	8	571	2e-42	171
tr:F3FB75_PSEA0	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.14	365	237	7	200	549	14	375	2e-42	169
rs:WP_025876744	DNA topoisomerase I [Prevotella corporis].	25.85	557	349	15	5	531	3	525	2e-42	172
tr:S4BMI7_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.60	558	331	19	7	548	63	563	2e-42	172
tr:J8WAQ0_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.85	555	339	21	24	563	2	504	2e-42	171
rs:WP_014299351	DNA topoisomerase III [Bacteroides fragilis].	26.63	567	344	19	7	531	2	538	2e-42	172
rs:WP_032737758	DNA topoisomerase III [Bifidobacterium longum].	26.02	561	361	14	7	539	4	538	2e-42	172
rs:WP_026660106	DNA topoisomerase III [Butyrivibrio sp. AC2005].	26.77	609	377	17	5	554	4	602	2e-42	171
rs:WP_010815630	DNA topoisomerase III [Enterococcus faecalis].	26.67	615	387	22	7	606	4	569	2e-42	171
tr:A2SCD8_METPP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.33	600	377	20	7	568	22	600	2e-42	173
tr:C9C9G9_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.78	490	325	11	89	563	2	482	2e-42	171
rs:WP_027384776	DNA topoisomerase III [Chryseobacterium caeni].	28.36	543	336	19	8	531	5	513	3e-42	172
rs:WP_043431407	ATP-dependent DNA helicase RecQ [Cystobacter fuscus].	26.20	603	361	19	3	547	7	583	3e-42	175
rs:WP_046213986	DNA topoisomerase III [Paenibacillus wulumuqiensis].	26.32	627	393	22	7	599	5	596	3e-42	172
rs:WP_016421320	DNA topoisomerase III [Capnocytophaga granulosa].	26.25	621	389	18	4	590	1	586	3e-42	172
rs:WP_004081462	DNA topoisomerase III [Clostridium sp. ASF502].	27.30	586	363	16	1	563	1	546	3e-42	171
rs:WP_025477199	DNA topoisomerase III, partial [Enterococcus faecium].	27.78	540	321	22	41	563	1	488	3e-42	171
rs:WP_028905786	DNA topoisomerase I [Prevotella intermedia].	27.16	545	341	18	5	531	3	509	3e-42	171
rs:WP_033563343	DNA topoisomerase I [Sphingobacteriaceae bacterium DW12].	27.19	559	346	15	4	531	1	529	3e-42	171
rs:WP_032887862	DNA topoisomerase [Fusobacterium nucleatum].	26.92	561	353	14	7	539	4	535	3e-42	171
rs:WP_012655857	hypothetical protein [Macrococcus caseolyticus].	29.34	559	353	21	5	543	3	539	3e-42	172
rs:WP_045167716	DNA topoisomerase III [Prevotella intermedia].	27.32	560	336	20	8	531	5	529	3e-42	171
rs:WP_026903538	DNA topoisomerase III [Pedobacter glucosidilyticus].	27.80	554	338	18	7	531	4	524	3e-42	171
rs:WP_004825718	DNA topoisomerase III [Peptoniphilus lacrimalis].	26.67	540	348	14	7	539	4	502	3e-42	171
tr:A0A0D8IWN4_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KJF39097.1};	26.43	560	356	14	7	550	4	523	3e-42	171
rs:WP_028902015	DNA topoisomerase I [Prevotella corporis].	25.85	557	349	15	5	531	3	525	3e-42	171
rs:WP_032576270	DNA topoisomerase III [Bacteroides fragilis].	26.63	567	344	19	7	531	2	538	3e-42	172
rs:WP_026649430	DNA topoisomerase III [Blautia wexlerae].	26.37	603	354	20	8	532	7	597	3e-42	172
rs:WP_032581749	DNA topoisomerase III [Bacteroides fragilis].	26.63	567	344	19	7	531	2	538	3e-42	171
rs:WP_020478294	ATP-dependent DNA helicase RecQ [Myxococcus xanthus].	26.24	587	357	17	2	531	24	591	3e-42	175
rs:WP_008657518	MULTISPECIES: DNA topoisomerase III [Bacteroides].	26.63	567	344	19	7	531	2	538	3e-42	171
rs:WP_022465005	DNA topoisomerase III [Clostridium sp. CAG:277].	27.26	620	361	22	7	550	6	611	3e-42	171
rs:WP_024635340	DNA topoisomerase III, partial [Enterococcus faecium].	27.78	540	321	22	41	563	1	488	3e-42	171
rs:WP_007665500	DNA topoisomerase I [Bacteroides intestinalis].	28.49	544	345	17	4	531	1	516	3e-42	171
rs:WP_000779867	DNA topoisomerase III [Streptococcus agalactiae].	25.70	611	398	18	7	606	4	569	3e-42	170
rs:WP_028319719	DNA topoisomerase III [Desulfobulbus elongatus].	28.27	612	385	22	5	592	4	585	3e-42	172
tr:C2BCS2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.75	542	345	16	7	539	8	506	3e-42	170
rs:WP_010784036	DNA topoisomerase III [Enterococcus faecalis].	27.35	563	338	19	1	548	1	507	3e-42	171
rs:WP_007654023	DNA topoisomerase I [Parabacteroides goldsteinii].	26.85	607	391	22	4	591	1	573	3e-42	171
rs:WP_031388728	DNA topoisomerase III, partial [Desulfonatronum thiodismutans].	27.52	505	339	12	5	498	3	491	3e-42	171
rs:WP_042902897	DNA topoisomerase [Streptococcus oralis].	26.48	559	358	16	4	550	2	519	3e-42	170
rs:WP_028896492	DNA topoisomerase I [Prevotella sp. HUN102].	26.44	571	356	17	4	550	2	532	3e-42	171
rs:WP_032684902	DNA topoisomerase III [Bifidobacterium longum].	26.20	561	360	14	7	539	4	538	3e-42	171
rs:WP_036910457	DNA topoisomerase III, partial [Prevotella sp. FD3004].	27.64	568	325	23	7	531	2	526	3e-42	171
rs:WP_014485593	DNA topoisomerase III [Bifidobacterium longum].	26.20	561	360	14	7	539	4	538	3e-42	171
rs:WP_034347888	DNA topoisomerase III, partial [Helicobacter trogontum].	25.76	594	373	18	8	559	5	572	3e-42	171
rs:WP_009906246	DNA topoisomerase III [Peptoclostridium difficile].	28.52	568	339	18	7	550	4	528	3e-42	171
rs:WP_001995833	DNA topoisomerase III [Bacillus cereus].	29.14	549	319	19	43	550	46	565	3e-42	172
rs:WP_023155063	DNA topoisomerase [Escherichia coli].	28.01	614	393	19	7	590	4	598	3e-42	171
rs:WP_010817457	DNA topoisomerase III [Enterococcus faecalis].	27.00	563	340	18	1	548	1	507	3e-42	171
rs:WP_022338804	DNA topoisomerase [Clostridium sp. CAG:433].	28.01	582	340	23	7	550	4	544	3e-42	171
rs:WP_033121926	DNA topoisomerase III [Oscillibacter sp. ER4].	26.68	566	347	18	7	550	4	523	3e-42	171
rs:WP_022784300	DNA topoisomerase III [Lachnospiraceae bacterium NK4A179].	26.36	626	381	22	1	558	1	614	3e-42	171
rs:WP_034881273	DNA topoisomerase III [Bifidobacterium pseudocatenulatum].	26.42	632	364	24	7	579	4	593	3e-42	171
rs:WP_038323548	DNA topoisomerase III [bacterium MS4].	26.28	548	357	16	7	548	4	510	4e-42	171
rs:WP_039076293	DNA topoisomerase III [Bacillus sp. MSP13].	27.72	606	392	18	7	603	5	573	4e-42	171
rs:WP_002356083	DNA topoisomerase [Enterococcus faecium].	29.55	467	287	13	108	556	1	443	4e-42	169
rs:WP_033598758	DNA topoisomerase III [Enterococcus faecalis].	27.53	563	337	19	1	548	1	507	4e-42	171
tr:A0A0A6VJT5_BIFLN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHD94841.1};	26.47	563	356	14	7	539	4	538	4e-42	171
rs:WP_012974496	DNA topoisomerase III [Azospirillum lipoferum].	26.78	575	341	16	5	531	3	545	4e-42	172
rs:WP_000779861	DNA topoisomerase III [Streptococcus agalactiae].	26.43	541	348	15	7	539	4	502	4e-42	170
rs:WP_023925335	DNA topoisomerase III [Prevotella nigrescens].	26.90	565	332	20	8	531	5	529	4e-42	171
rs:WP_013063148	DNA topoisomerase III [Prevotella ruminicola].	27.57	573	330	21	7	531	2	537	4e-42	171
tr:L2R3E3_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.95	538	328	20	41	563	1	488	4e-42	171
rs:WP_002344553	DNA topoisomerase III, partial [Enterococcus faecium].	27.29	546	316	21	41	563	1	488	4e-42	171
tr:R2AXZ8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.15	540	319	22	41	563	1	488	4e-42	171
rs:WP_008707501	DNA topoisomerase III [Ruminococcus sp. 5_1_39BFAA].	26.37	603	354	20	8	532	7	597	4e-42	171
rs:WP_019132809	DNA topoisomerase [Peptoniphilus obesi].	25.53	611	399	18	7	606	4	569	4e-42	170
rs:WP_028790806	DNA topoisomerase III [Tetragenococcus muriaticus].	26.74	561	336	21	7	550	5	507	4e-42	171
tr:S9PA36_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.25	602	360	19	4	547	1	576	4e-42	174
rs:WP_033168144	DNA topoisomerase III [Clostridium sp. KNHs205].	24.81	665	408	21	8	590	7	661	4e-42	171
rs:WP_007130011	DNA topoisomerase III [Paenibacillus lactis].	26.53	622	389	20	5	590	3	592	4e-42	171
rs:WP_021983043	DNA topoisomerase III [Eubacterium sp. CAG:603].	26.85	581	359	20	8	532	7	577	4e-42	171
rs:WP_002979405	DNA topoisomerase [Chryseobacterium gleum].	28.13	551	340	17	4	531	1	518	4e-42	171
rs:WP_028610693	DNA topoisomerase III [Paenibacillus harenae].	25.16	636	405	19	5	600	3	607	4e-42	171
rs:WP_019192519	DNA topoisomerase [Anaerococcus pacaensis].	27.12	542	343	16	7	539	4	502	4e-42	170
rs:WP_022379889	DNA topoisomerase III [Ruminococcus sp. CAG:9].	26.37	603	354	20	8	532	7	597	4e-42	171
rs:WP_002993293	DNA topoisomerase [Sphingobacterium spiritivorum].	28.08	552	339	17	4	531	1	518	4e-42	171
tr:D4VW42_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.95	538	328	20	41	563	1	488	4e-42	171
rs:WP_009389013	DNA topoisomerase [Capnocytophaga sp. oral taxon 329].	27.05	599	362	18	4	566	1	560	4e-42	171
rs:WP_007156047	DNA topoisomerase III [Oribacterium sinus].	26.74	617	380	20	8	562	14	620	4e-42	171
rs:WP_028069430	DNA topoisomerase I [Sphingobacterium thalpophilum].	28.60	549	340	18	4	531	1	518	4e-42	171
rs:WP_025491694	DNA topoisomerase III [Clostridiales bacterium VE202-27].	26.89	569	351	18	3	550	2	526	4e-42	171
rs:WP_005934783	DNA topoisomerase III [Faecalibacterium prausnitzii].	26.96	560	353	17	7	550	4	523	4e-42	171
rs:WP_002978178	DNA topoisomerase [Chryseobacterium gleum].	27.62	572	351	17	4	550	1	534	4e-42	171
rs:WP_032542096	DNA topoisomerase III, partial [Peptoclostridium difficile].	26.33	528	331	14	43	549	14	504	4e-42	171
rs:WP_039423446	DNA topoisomerase I [Porphyromonas gulae].	26.93	557	333	18	7	531	4	518	4e-42	171
rs:WP_033493981	DNA topoisomerase III [Bifidobacterium thermophilum].	27.01	585	348	20	7	548	4	552	5e-42	171
rs:WP_022268381	DNA topoisomerase [Firmicutes bacterium CAG:424].	26.47	597	379	17	7	554	6	591	5e-42	171
rs:WP_002307507	DNA topoisomerase [Enterococcus faecium].	29.55	467	287	13	108	556	1	443	5e-42	169
rs:WP_008432102	DNA topoisomerase III [Planococcus donghaensis].	29.46	560	345	19	7	544	5	536	5e-42	171
rs:WP_019034344	DNA topoisomerase III [Peptoniphilus lacrimalis].	26.19	611	391	19	7	604	4	567	5e-42	170
rs:WP_034867809	DNA topoisomerase I [Elizabethkingia miricola].	28.28	580	338	20	4	550	1	535	5e-42	171
rs:WP_031471795	DNA topoisomerase III, partial [[Clostridium] aminophilum].	24.72	627	383	20	3	550	2	618	5e-42	171
rs:WP_044904689	DNA topoisomerase III [[Clostridium] innocuum].	25.42	539	354	15	26	550	2	506	5e-42	171
rs:WP_013816520	DNA topoisomerase I [Porphyromonas gingivalis].	26.75	557	334	18	7	531	4	518	5e-42	171
rs:WP_002329557	DNA topoisomerase III, partial [Enterococcus faecium].	27.29	546	316	21	41	563	1	488	5e-42	171
rs:WP_004461886	DNA topoisomerase III [[Clostridium] symbiosum].	25.93	594	356	22	8	532	7	585	5e-42	171
rs:WP_004081256	DNA topoisomerase III [Clostridium sp. ASF502].	26.68	566	351	15	7	550	6	529	5e-42	171
rs:WP_029493414	DNA topoisomerase III [Fusobacterium hwasookii].	26.75	557	359	13	7	539	4	535	5e-42	170
rs:WP_045265866	DNA topoisomerase III [Comamonas aquatica].	27.49	593	354	24	5	550	4	567	5e-42	173
rs:WP_021665030	DNA topoisomerase [Porphyromonas gingivalis].	26.55	565	341	18	7	539	4	526	5e-42	171
rs:WP_005467933	DNA topoisomerase [Porphyromonas catoniae].	25.80	566	344	15	5	539	3	523	5e-42	171
rs:WP_007574002	DNA topoisomerase III [Prevotella multisaccharivorax].	26.94	553	345	18	7	531	2	523	5e-42	171
tr:E0GRL9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.42	558	332	19	7	548	63	563	5e-42	171
rs:WP_002360012	DNA topoisomerase III [Enterococcus faecalis].	27.00	563	340	18	1	548	1	507	5e-42	171
rs:WP_004360034	DNA topoisomerase I [Prevotella melaninogenica].	27.40	551	340	16	4	531	2	515	5e-42	171
rs:WP_025070215	DNA topoisomerase I [Prevotella oulorum].	27.22	551	339	17	5	531	3	515	5e-42	171
rs:WP_042100636	DNA topoisomerase III [Escherichia coli].	28.42	570	355	17	7	544	4	552	5e-42	171
rs:WP_025883360	DNA topoisomerase I [Porphyromonas uenonis].	26.91	576	348	18	5	552	3	533	5e-42	171
rs:WP_002672191	DNA topoisomerase [Capnocytophaga ochracea].	26.72	595	369	17	4	566	1	560	5e-42	171
rs:WP_034736742	DNA topoisomerase I [Chryseobacterium indologenes].	28.45	580	337	20	4	550	1	535	5e-42	171
tr:L2QP66_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.96	540	320	22	41	563	1	488	5e-42	170
rs:WP_025067452	DNA topoisomerase I [Prevotella denticola].	27.19	559	362	15	4	543	1	533	5e-42	171
rs:WP_006892423	DNA topoisomerase [Methylobacter tundripaludum].	28.37	557	338	18	4	531	1	525	5e-42	171
rs:WP_032566369	DNA topoisomerase I [Bacteroides fragilis].	26.30	616	391	20	4	591	1	581	5e-42	171
rs:WP_035170845	hypothetical protein [Campylobacter fetus].	26.63	567	374	18	8	553	5	550	5e-42	170
rs:WP_009124378	DNA topoisomerase III [Bacteroides fluxus].	25.48	569	359	18	7	531	2	549	5e-42	171
rs:WP_025434822	DNA topoisomerase [Eubacterium acidaminophilum].	26.89	543	345	17	7	539	4	504	5e-42	169
rs:WP_010393247	DNA topoisomerase III [Janthinobacterium lividum].	27.87	574	364	18	5	550	4	555	5e-42	172
rs:WP_001235743	DNA topoisomerase III [Escherichia coli].	28.60	570	354	18	7	544	4	552	6e-42	171
rs:WP_007593005	DNA topoisomerase III [Lachnoanaerobaculum sp. OBRC5-5].	26.79	560	354	17	7	550	4	523	6e-42	171
rs:WP_028908338	DNA topoisomerase III [Prevotella ruminicola].	27.40	573	331	21	7	531	2	537	6e-42	171
rs:WP_009148607	DNA topoisomerase III [Thiorhodovibrio sp. 970].	26.96	601	347	19	5	539	3	577	6e-42	172
rs:WP_036235380	DNA topoisomerase III [Massilia sp. JS1662].	27.33	622	397	18	7	605	6	595	6e-42	172
rs:WP_019969023	DNA topoisomerase I [Prevotella maculosa].	27.10	583	356	18	4	543	1	557	6e-42	171
rs:WP_016218703	DNA topoisomerase III [Dorea sp. 5-2].	26.44	624	380	23	8	570	7	612	6e-42	170
gp:CP007064_1426	DNA topoisomerase III [Fusobacterium nucleatum subsp. vincentii 3_1_27]	27.99	586	364	21	7	573	4	550	6e-42	170
rs:WP_045244502	DNA topoisomerase III [Paenibacillus polymyxa].	25.52	627	402	19	5	599	3	596	6e-42	171
tr:T1CM99_9HELI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.80	562	374	15	7	546	4	544	6e-42	170
rs:WP_028604968	DNA topoisomerase III [Ottowia thiooxydans].	26.89	636	374	22	5	568	3	619	6e-42	173
rs:WP_019975895	DNA topoisomerase [Empedobacter brevis].	28.70	561	324	19	4	531	1	518	6e-42	170
rs:WP_031620292	DNA topoisomerase III, partial [Salmonella enterica].	28.37	557	346	17	7	531	4	539	6e-42	169
rs:WP_022066938	DNA topoisomerase III [Blautia sp. CAG:257].	26.62	601	375	22	8	554	7	595	6e-42	170
rs:WP_008783291	DNA topoisomerase III [Bifidobacterium sp. 12_1_47BFAA].	26.20	561	360	14	7	539	4	538	6e-42	171
rs:WP_007054353	DNA topoisomerase III [Bifidobacterium longum].	26.02	561	361	14	7	539	4	538	7e-42	171
tr:B8DNH0_DESVM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.95	582	369	14	3	539	2	566	7e-42	172
rs:WP_036679138	DNA topoisomerase I [Pedobacter oryzae].	28.01	564	348	17	7	543	4	536	7e-42	170
rs:WP_044478733	DNA topoisomerase III [Paenibacillus sp. GD11].	26.42	632	390	21	5	599	3	596	7e-42	171
rs:WP_003010128	DNA topoisomerase [Sphingobacterium spiritivorum].	28.08	552	339	17	4	531	1	518	7e-42	170
rs:WP_019118541	DNA topoisomerase III [Anaerococcus obesiensis].	26.07	610	397	20	7	606	4	569	7e-42	169
rs:WP_026984412	DNA topoisomerase I [Flavobacterium sp. URHB0058].	27.68	560	348	19	4	539	1	527	7e-42	170
tr:D7GWX3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.90	610	374	20	7	550	6	603	7e-42	170
rs:WP_033553424	DNA topoisomerase III [Escherichia coli].	28.01	557	347	19	8	531	5	540	7e-42	171
rs:WP_009589194	DNA topoisomerase III [Paenibacillus sp. HGF5].	26.23	629	396	19	5	599	3	597	7e-42	171
rs:WP_042371906	DNA topoisomerase I [Bacteroidaceae bacterium MS4].	26.52	607	389	22	7	591	4	575	7e-42	170
rs:WP_025365018	DNA topoisomerase III [Paenibacillus polymyxa].	25.52	627	402	19	5	599	3	596	7e-42	171
tr:E0GLT5_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.42	558	332	19	7	548	63	563	7e-42	171
rs:WP_009730737	DNA topoisomerase III [Streptococcus sp. F0441].	26.61	560	356	16	4	550	2	519	7e-42	169
rs:WP_014125497	DNA topoisomerase III [Tetragenococcus halophilus].	26.69	562	335	21	7	550	5	507	7e-42	170
rs:WP_045092577	DNA topoisomerase III [Clostridium sp. FS41].	25.67	600	361	20	8	532	7	596	7e-42	170
rs:WP_031480058	DNA topoisomerase I [Desulfovibrio frigidus].	26.76	583	388	16	7	567	4	569	7e-42	171
rs:WP_002414495	DNA topoisomerase III [Enterococcus faecalis].	27.00	563	340	18	1	548	1	507	7e-42	170
rs:WP_002364251	DNA topoisomerase III [Enterococcus faecalis].	27.00	563	340	18	1	548	1	507	7e-42	170
rs:WP_032881471	DNA topoisomerase III [Pseudomonas sp. BRG-100].	27.48	604	384	16	8	574	5	591	7e-42	170
rs:WP_046217659	DNA topoisomerase III, partial [Bacillus endophyticus].	29.36	436	263	9	107	535	11	408	7e-42	169
rs:WP_003458909	DNA topoisomerase III [Clostridium perfringens].	29.51	566	344	19	7	550	5	537	7e-42	170
rs:WP_022438332	DNA topoisomerase III [Clostridium sp. CAG:411].	27.56	606	374	17	3	553	2	597	7e-42	170
rs:WP_002573997	DNA topoisomerase III [[Clostridium] bolteae].	26.03	634	392	22	3	607	2	587	7e-42	170
rs:WP_010494009	DNA topoisomerase III, partial [Paenibacillus elgii].	26.28	624	391	20	5	590	3	595	7e-42	170
tr:A0A0A1SBJ6_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.52	554	341	21	7	543	5	520	7e-42	170
rs:WP_004835552	DNA topoisomerase III [Anaerococcus prevotii].	26.39	610	391	20	7	604	4	567	8e-42	169
rs:WP_042421644	DNA topoisomerase III [Comamonas granuli].	27.47	608	375	21	3	568	2	585	8e-42	172
rs:WP_034700637	DNA topoisomerase III [Enterococcus hirae].	27.24	525	315	19	41	550	1	473	8e-42	170
rs:WP_044786072	DNA topoisomerase III [Paenibacillus polymyxa].	25.52	627	402	19	5	599	3	596	8e-42	171
rs:WP_008797619	type I topoisomerase [Fusobacterium nucleatum].	27.99	586	364	21	7	573	8	554	8e-42	170
tr:A8U7S1_9LACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.94	559	348	17	5	550	13	518	8e-42	170
rs:WP_037599285	DNA topoisomerase [Streptococcus sp. ACS2].	25.70	572	376	16	7	569	6	537	8e-42	169
rs:WP_012797160	DNA topoisomerase III [Anaerococcus prevotii].	26.02	611	392	20	7	604	4	567	8e-42	169
rs:WP_017427723	MULTISPECIES: DNA topoisomerase III [Paenibacillus].	25.52	627	402	19	5	599	3	596	8e-42	171
rs:WP_004364408	DNA topoisomerase III [Prevotella nigrescens].	26.62	571	353	17	5	550	3	532	8e-42	170
rs:WP_029515045	DNA topoisomerase III [Paenibacillus polymyxa].	25.52	627	402	19	5	599	3	596	8e-42	171
rs:WP_029514379	DNA topoisomerase III [Paenibacillus polymyxa].	25.52	627	402	19	5	599	3	596	8e-42	171
rs:WP_029276362	MULTISPECIES: DNA topoisomerase III [Carnobacterium].	25.94	559	348	17	5	550	3	508	8e-42	170
rs:WP_039276074	DNA topoisomerase III [Paenibacillus polymyxa].	25.52	627	402	19	5	599	3	596	8e-42	171
rs:WP_016304287	DNA topoisomerase III [Lachnospiraceae bacterium A2].	28.65	555	331	19	7	539	4	515	8e-42	170
rs:WP_036279667	DNA topoisomerase III [Methylocystis sp. ATCC 49242].	27.52	585	342	19	5	550	3	544	8e-42	170
rs:WP_024725165	hypothetical protein [Clostridiales bacterium VE202-03].	27.41	580	358	20	7	559	4	547	9e-42	170
tr:R9II52_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.71	569	352	14	7	548	4	534	9e-42	170
rs:WP_005421647	hypothetical protein [[Ruminococcus] obeum].	25.49	565	359	18	7	550	6	529	9e-42	170
rs:WP_008665854	DNA topoisomerase I [Bacteroides sp. 4_1_36].	25.87	603	393	16	4	592	1	563	9e-42	170
rs:WP_043533225	DNA topoisomerase III [Klebsiella pneumoniae].	28.42	563	352	17	7	540	4	544	9e-42	170
rs:WP_002336691	DNA topoisomerase III [Enterococcus faecium].	29.76	467	286	13	108	556	1	443	9e-42	169
rs:WP_024234184	DNA topoisomerase III [Escherichia coli].	27.99	568	360	15	7	544	4	552	9e-42	170
rs:WP_032557817	DNA topoisomerase I [Bacteroides fragilis].	25.79	605	400	18	4	591	1	573	1e-41	170
tr:A0A015WCI0_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EXZ05162.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EXZ05162.1};	27.21	544	352	16	4	531	2	517	1e-41	170
rs:WP_002342368	DNA topoisomerase III [Enterococcus faecium].	29.55	467	287	13	108	556	1	443	1e-41	168
rs:WP_034229460	DNA topoisomerase III [Lachnospiraceae bacterium 3-1].	26.71	569	352	14	7	548	6	536	1e-41	170
rs:WP_010737146	MULTISPECIES: DNA topoisomerase III, partial [Enterococcus].	27.24	525	315	19	41	550	1	473	1e-41	169
rs:WP_022426265	DNA topoisomerase [Ruminococcus sp. CAG:90].	28.65	562	339	22	23	532	8	559	1e-41	169
rs:WP_026707121	DNA topoisomerase I [Flavobacterium frigidarium].	27.90	552	340	19	4	531	1	518	1e-41	170
rs:WP_007057140	DNA topoisomerase III [Bifidobacterium longum].	26.20	561	360	14	7	539	4	538	1e-41	170
rs:WP_016479364	DNA topoisomerase III [Capnocytophaga sp. oral taxon 336].	26.80	597	366	18	4	566	1	560	1e-41	170
tr:D4X4C7_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.50	556	344	21	5	536	3	534	1e-41	171
rs:WP_032557320	DNA topoisomerase III [Bacteroides fragilis].	26.46	567	345	19	7	531	2	538	1e-41	170
rs:WP_021388553	DNA topoisomerase III [Peptoclostridium difficile].	27.82	568	343	17	7	550	4	528	1e-41	170
rs:WP_010720799	DNA topoisomerase III, partial [Enterococcus hirae].	27.24	525	315	19	41	550	1	473	1e-41	169
rs:WP_039882454	DNA topoisomerase [Achromobacter piechaudii].	29.50	556	344	21	5	536	4	535	1e-41	171
rs:WP_034930384	DNA topoisomerase III [Candidatus Accumulibacter sp. SK-01].	28.30	583	351	21	7	550	6	560	1e-41	171
rs:WP_032735465	DNA topoisomerase III [Bifidobacterium longum].	26.02	561	361	14	7	539	4	538	1e-41	170
rs:WP_036889370	DNA topoisomerase I [Porphyromonas crevioricanis].	26.17	554	344	15	4	531	2	516	1e-41	169
rs:WP_032568947	DNA topoisomerase III [Bacteroides fragilis].	26.46	567	345	19	7	531	2	538	1e-41	170
rs:WP_007857917	DNA topoisomerase III [[Clostridium] citroniae].	25.50	600	362	20	8	532	7	596	1e-41	170
rs:WP_002341369	DNA topoisomerase III [Enterococcus faecium].	29.34	467	288	13	108	556	1	443	1e-41	167
rs:WP_031461576	DNA topoisomerase III [Paenibacillus polymyxa].	25.52	627	402	19	5	599	3	596	1e-41	170
tr:A0A078QAC8_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:KDS20329.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KDS20329.1};	26.80	571	361	17	4	552	2	537	1e-41	169
rs:WP_015238851	DNA topoisomerase III [Candidatus Kinetoplastibacterium crithidii].	27.52	585	382	16	7	568	6	571	1e-41	171
rs:WP_043320923	ATP-dependent DNA helicase RecQ [Corallococcus coralloides].	26.73	591	352	21	2	531	27	597	1e-41	173
tr:S4DYY5_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.75	536	340	17	24	550	2	488	1e-41	169
tr:W1H5Z8_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.73	358	232	8	203	548	1	354	1e-41	167
rs:WP_045167309	DNA topoisomerase I [Prevotella intermedia].	26.99	552	335	18	4	531	2	509	1e-41	169
rs:WP_035779454	DNA topoisomerase III, partial [Clostridium butyricum].	28.37	504	308	16	7	491	4	473	1e-41	167
rs:WP_008982250	DNA topoisomerase III [Ruminococcaceae bacterium D16].	26.25	560	357	16	7	550	4	523	1e-41	169
rs:WP_032586616	DNA topoisomerase I [Bacteroides fragilis].	26.10	613	396	19	4	591	1	581	1e-41	169
rs:WP_042825712	conjugal transfer protein TraE [Xanthomonas axonopodis].	25.69	576	372	17	7	548	4	557	1e-41	170
tr:H8N181_CORCM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.73	591	352	21	2	531	32	602	1e-41	173
rs:WP_005800102	DNA topoisomerase I [Bacteroides fragilis].	26.14	616	392	20	4	591	1	581	1e-41	169
rs:WP_028996896	DNA topoisomerase III [Azohydromonas australica].	29.04	575	349	22	3	540	2	554	1e-41	171
rs:WP_041992690	hypothetical protein [Capnocytophaga cynodegmi].	26.26	575	356	17	7	552	4	539	1e-41	169
rs:WP_026382163	DNA topoisomerase [Achromobacter xylosoxidans].	29.50	556	344	21	5	536	4	535	1e-41	171
tr:W1HVM3_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.73	358	232	8	203	548	1	354	1e-41	167
rs:WP_018112824	DNA topoisomerase III [Peptoclostridium difficile].	27.87	567	344	16	7	550	4	528	1e-41	169
rs:WP_009235005	DNA topoisomerase III [Prevotella sp. oral taxon 472].	27.01	548	343	19	7	531	2	515	1e-41	169
rs:WP_024236378	DNA topoisomerase III [Escherichia coli].	28.25	570	356	17	7	544	4	552	1e-41	169
rs:WP_004331500	DNA topoisomerase I [Porphyromonas asaccharolytica].	26.69	547	346	15	5	531	3	514	1e-41	169
rs:WP_016504282	DNA topoisomerase III, partial [Pasteurella multocida].	36.05	294	168	10	279	559	34	320	1e-41	165
rs:WP_001235737	DNA topoisomerase III [Salmonella enterica].	28.25	570	356	17	7	544	4	552	1e-41	169
rs:WP_020151346	hypothetical protein [Verrucomicrobia bacterium SCGC AAA164-M04].	28.52	596	355	21	3	554	2	570	1e-41	171
rs:WP_005805798	DNA topoisomerase I [Bacteroides fragilis].	27.37	570	348	18	7	550	10	539	1e-41	169
rs:WP_004577989	Topoisomerase IA, partial [nanoarchaeote Nst1].	27.79	547	313	20	7	531	3	489	1e-41	167
rs:WP_002349886	DNA topoisomerase, partial [Enterococcus faecium].	28.63	531	345	14	52	563	1	516	1e-41	169
tr:R0AE94_CLOBU	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.37	504	308	16	7	491	4	473	1e-41	167
rs:WP_006209708	DNA topoisomerase III [Paenibacillus vortex].	26.30	635	389	20	5	599	3	598	1e-41	170
rs:WP_024994449	DNA topoisomerase III [Bacteroides paurosaccharolyticus].	27.88	556	348	18	7	531	2	535	1e-41	169
rs:WP_009323494	DNA topoisomerase III [Subdoligranulum sp. 4_3_54A2FAA].	26.96	560	353	17	7	550	4	523	1e-41	169
rs:WP_027851694	DNA topoisomerase III [Marinospirillum insulare].	26.59	583	358	18	7	543	5	563	1e-41	170
rs:WP_022411924	DNA topoisomerase III [Ruminococcus sp. CAG:330].	28.60	563	338	21	7	548	4	523	1e-41	169
rs:WP_042840071	DNA topoisomerase III [Salmonella enterica].	28.25	570	356	17	7	544	4	552	1e-41	169
rs:WP_023055012	DNA topoisomerase III [Peptoniphilus sp. BV3C26].	25.90	610	396	19	7	605	4	568	1e-41	168
tr:A0A016FRT4_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EYA20988.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EYA20988.1};	26.92	572	359	18	4	552	2	537	1e-41	169
rs:WP_000864636	DNA topoisomerase [Bacillus cereus].	25.54	466	306	12	4	449	1	445	1e-41	166
rs:WP_008449295	DNA topoisomerase III [Prevotella amnii].	27.06	558	345	17	8	531	5	534	1e-41	169
rs:WP_025643309	DNA topoisomerase III [[Clostridium] scindens].	26.89	595	378	20	8	554	7	592	1e-41	169
rs:WP_032536062	MULTISPECIES: DNA topoisomerase I [Bacteroides].	27.37	570	348	18	7	550	10	539	1e-41	169
rs:WP_038821515	DNA topoisomerase III, partial [Pseudomonas syringae].	31.99	322	208	6	43	361	3	316	1e-41	163
rs:WP_032881383	DNA topoisomerase [Fusobacterium nucleatum].	27.91	584	367	21	7	573	8	554	1e-41	169
tr:M5T3X4_9PLAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.01	557	348	20	4	534	2	531	2e-41	171
rs:WP_028403521	DNA topoisomerase III [Bacillus sp. J13].	26.37	622	390	20	5	590	3	592	2e-41	170
rs:WP_021663330	DNA topoisomerase [Porphyromonas gingivalis].	26.40	553	341	18	7	531	4	518	2e-41	169
rs:WP_010801747	MULTISPECIES: DNA topoisomerase III [Bacteroidales].	26.12	605	398	18	4	591	1	573	2e-41	169
rs:WP_003464928	DNA topoisomerase III [Clostridium perfringens].	29.68	566	343	18	7	550	5	537	2e-41	169
rs:WP_032738539	DNA topoisomerase III [Bifidobacterium longum].	26.02	561	361	14	7	539	4	538	2e-41	169
rs:WP_016271901	DNA topoisomerase III [Bacteroides vulgatus].	26.12	605	398	18	4	591	1	573	2e-41	169
rs:WP_045167922	DNA topoisomerase I [Prevotella intermedia].	26.96	575	347	21	5	552	3	531	2e-41	169
rs:WP_035262180	hypothetical protein, partial [Desulfonatronum lacustre].	28.71	505	329	14	7	498	5	491	2e-41	169
rs:WP_010822981	DNA topoisomerase III [Enterococcus faecalis].	27.35	563	338	19	1	548	1	507	2e-41	169
rs:WP_001556719	DNA topoisomerase III [Escherichia coli].	27.82	568	361	15	7	544	4	552	2e-41	169
rs:WP_045538028	DNA topoisomerase III, partial [Comamonadaceae bacterium B1].	27.12	590	373	20	2	550	6	579	2e-41	171
tr:R9I6C5_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS11739.1};	26.03	580	353	19	2	531	13	566	2e-41	169
rs:WP_008672316	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	25.95	605	399	19	4	591	1	573	2e-41	169
rs:WP_036685684	DNA topoisomerase III [Paenibacillus sp. MSt1].	26.60	624	389	22	5	590	3	595	2e-41	170
rs:WP_020531862	hypothetical protein [Flexithrix dorotheae].	27.51	618	384	19	4	598	1	577	2e-41	170
rs:WP_001567310	DNA topoisomerase III [Escherichia coli].	27.82	568	361	15	7	544	4	552	2e-41	169
rs:WP_015045035	DNA topoisomerase III [Dehalobacter sp. CF].	27.96	558	326	20	7	539	4	510	2e-41	169
rs:WP_002584840	MULTISPECIES: DNA topoisomerase III [Lachnoclostridium].	26.11	563	338	17	7	539	4	518	2e-41	169
rs:WP_000237216	DNA topoisomerase III [Streptococcus pneumoniae].	26.30	559	359	15	4	550	2	519	2e-41	168
rs:WP_031942376	DNA topoisomerase III [Escherichia coli].	27.82	568	361	15	7	544	4	552	2e-41	169
rs:WP_028585602	DNA topoisomerase III [Desulfobulbus mediterraneus].	27.45	612	391	23	5	592	4	586	2e-41	170
rs:WP_031770311	DNA topoisomerase III [Staphylococcus aureus].	28.68	551	342	18	5	531	3	526	2e-41	169
rs:WP_006266598	DNA topoisomerase [Myroides odoratimimus].	26.01	569	368	16	4	552	1	536	2e-41	169
rs:WP_018967490	DNA topoisomerase III [Prevotella loescheii].	27.01	548	343	19	7	531	2	515	2e-41	169
rs:WP_038426447	DNA topoisomerase III [Bifidobacterium longum].	26.02	561	361	14	7	539	4	538	2e-41	169
tr:U7T6W8_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.91	584	367	21	7	573	4	550	2e-41	169
rs:WP_005867781	DNA topoisomerase I [Parabacteroides distasonis].	26.73	606	383	20	4	592	1	562	2e-41	169
rs:WP_022263573	DNA topoisomerase III [Butyrivibrio sp. CAG:318].	26.44	609	371	22	8	553	7	601	2e-41	169
rs:WP_001235751	DNA topoisomerase III [Escherichia coli].	27.82	568	361	15	7	544	4	552	2e-41	169
rs:WP_004066586	DNA topoisomerase III [Eubacterium plexicaudatum].	27.41	613	359	23	8	554	7	599	2e-41	169
rs:WP_038136279	DNA topoisomerase III [Verrucomicrobia bacterium SCGC AAA168-F10].	28.52	596	355	21	3	554	2	570	2e-41	170
rs:WP_012291470	topoisomerase IA [Escherichia coli].	27.82	568	361	15	7	544	4	552	2e-41	169
rs:WP_034727120	DNA topoisomerase I [Chryseobacterium sp. JM1].	27.88	556	335	18	4	531	1	518	2e-41	169
rs:WP_008396829	DNA topoisomerase III [Clostridium sp. M62/1].	26.79	560	354	17	7	550	4	523	2e-41	169
rs:WP_001565875	DNA topoisomerase III [Escherichia coli].	28.42	570	355	17	7	544	4	552	2e-41	169
rs:WP_021680133	DNA topoisomerase [Porphyromonas gingivalis].	27.78	558	345	19	7	539	4	528	2e-41	169
rs:WP_039445299	conjugal transfer protein TraE [Xanthomonas vasicola].	25.52	576	373	17	7	548	4	557	2e-41	169
rs:WP_022490063	DNA topoisomerase [Clostridium sp. CAG:567].	29.74	390	230	10	201	552	29	412	2e-41	166
rs:WP_005667883	DNA topoisomerase III [Massilia timonae].	28.50	565	363	17	7	550	6	550	2e-41	171
rs:WP_029491115	DNA topoisomerase III [Fusobacterium hwasookii].	26.74	561	354	14	7	539	4	535	2e-41	168
tr:A0A068N6R0_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.11	455	289	12	103	548	29	463	2e-41	168
rs:WP_032890733	DNA topoisomerase [Fusobacterium nucleatum].	27.50	560	348	19	7	550	8	525	2e-41	169
rs:WP_047299168	DNA topoisomerase III [Bifidobacterium bifidum].	27.06	595	345	22	7	549	4	561	2e-41	169
rs:WP_022399462	DNA topoisomerase III [Roseburia sp. CAG:471].	26.28	567	350	19	7	552	4	523	2e-41	169
rs:WP_010719185	DNA topoisomerase III [Enterococcus hirae].	26.42	617	351	21	5	599	3	538	2e-41	169
rs:WP_022765397	DNA topoisomerase III [Butyrivibrio sp. XPD2006].	26.90	591	363	19	1	532	1	581	2e-41	169
rs:WP_047270549	DNA topoisomerase III [Bifidobacterium bifidum].	26.81	593	349	21	7	549	4	561	2e-41	169
rs:WP_036870016	DNA topoisomerase I [Prevotella histicola].	26.59	549	345	15	5	531	3	515	2e-41	169
rs:WP_044254218	DNA topoisomerase [Rhodopirellula sp. SWK7].	28.01	557	348	20	4	534	1	530	2e-41	170
tr:A0A060NXQ2_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.12	590	373	20	2	550	7	580	2e-41	171
rs:WP_044822506	DNA topoisomerase III [Bacillus thuringiensis].	28.96	549	320	19	43	550	46	565	2e-41	170
rs:WP_021975616	topoisomerase IA [Bifidobacterium longum CAG:69].	26.02	561	361	14	7	539	4	538	2e-41	169
rs:WP_035029208	DNA topoisomerase III [Carnobacterium mobile].	26.84	570	329	20	5	550	3	508	2e-41	169
rs:WP_004343312	MULTISPECIES: DNA topoisomerase I [Prevotellaceae].	27.55	559	337	18	5	531	3	525	2e-41	169
rs:WP_036856717	DNA topoisomerase I [Prevotella amnii].	26.81	552	342	16	4	531	2	515	2e-41	169
rs:WP_010728928	DNA topoisomerase III [Enterococcus faecium].	29.34	467	288	13	108	556	1	443	2e-41	167
rs:WP_042415945	DNA topoisomerase III [Comamonas aquatica].	27.32	593	355	23	5	550	4	567	2e-41	171
rs:WP_022056443	DNA topoisomerase III [Clostridium sp. CAG:167].	27.22	654	402	26	7	601	6	644	2e-41	169
tr:D2U0X3_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.63	537	360	12	18	532	5	529	2e-41	169
rs:WP_002588973	DNA topoisomerase III, partial [[Clostridium] clostridioforme].	27.89	459	279	11	110	549	21	446	2e-41	168
rs:WP_015512177	Topoisomerase IA [Bifidobacterium longum].	26.02	561	361	14	7	539	4	538	2e-41	169
rs:WP_043378607	DNA topoisomerase III [Comamonas aquatica].	27.32	593	355	23	5	550	4	567	2e-41	171
rs:WP_011068071	DNA topoisomerase III [Bifidobacterium longum].	26.20	561	360	15	7	539	163	697	2e-41	170
rs:WP_035290026	DNA topoisomerase III [Clostridium sp. KNHs214].	27.58	562	351	15	7	550	4	527	2e-41	169
rs:WP_010297015	DNA topoisomerase III [Clostridium senegalense].	27.11	616	391	20	5	590	3	590	2e-41	168
rs:WP_047215475	DNA topoisomerase III [Pandoraea thiooxydans].	27.29	601	374	21	7	571	6	579	2e-41	170
rs:WP_004320647	DNA topoisomerase I [Bacteroides ovatus].	25.45	605	402	15	4	591	1	573	2e-41	169
rs:WP_044784436	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	28.96	549	320	19	43	550	46	565	2e-41	170
rs:WP_024360979	DNA topoisomerase III [Lysinibacillus sphaericus].	26.71	569	377	16	7	556	6	553	2e-41	169
rs:WP_038330896	DNA topoisomerase I [Empedobacter falsenii].	28.47	576	342	20	4	550	1	535	2e-41	169
rs:WP_029427372	DNA topoisomerase I [Bacteroides cellulosilyticus].	26.62	571	362	17	4	552	1	536	2e-41	169
rs:WP_004585380	DNA topoisomerase [Porphyromonas gingivalis].	27.50	560	326	21	7	531	4	518	2e-41	169
rs:WP_025800019	DNA topoisomerase I [Prevotella saccharolytica].	26.93	583	357	18	4	543	1	557	3e-41	169
tr:X7RXE5_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.50	560	348	19	7	550	4	521	3e-41	168
rs:WP_019375117	DNA topoisomerase III [Alicycliphilus sp. CRZ1].	27.03	603	362	22	3	550	2	581	3e-41	171
rs:WP_009433650	DNA topoisomerase I [Porphyromonas sp. oral taxon 279].	25.57	571	349	15	5	544	3	528	3e-41	169
rs:WP_036854427	DNA topoisomerase III [Prevotella amnii].	27.06	558	345	17	8	531	5	534	3e-41	168
rs:WP_032594315	DNA topoisomerase I [Bacteroides fragilis].	27.02	544	353	16	4	531	1	516	3e-41	168
rs:WP_014262114	DNA topoisomerase III [Filifactor alocis].	28.36	543	334	19	7	539	6	503	3e-41	167
rs:WP_040084152	DNA topoisomerase III [Escherichia coli].	27.64	568	362	15	7	544	4	552	3e-41	169
rs:WP_004602163	DNA topoisomerase III [[Eubacterium] cellulosolvens].	27.38	599	356	20	3	532	2	590	3e-41	169
tr:D4LVC5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.49	565	359	18	7	550	6	529	3e-41	168
rs:WP_042988804	hypothetical protein [Vibrio cholerae].	25.04	559	379	13	7	539	4	548	3e-41	169
rs:WP_025219815	DNA topoisomerase III [Lysinibacillus varians].	26.71	569	377	16	7	556	6	553	3e-41	169
rs:WP_002377042	DNA topoisomerase III [Enterococcus faecalis].	27.00	563	340	18	1	548	1	507	3e-41	168
rs:WP_042994340	DNA topoisomerase I [Bacteroides fragilis].	26.62	571	362	17	4	552	1	536	3e-41	168
rs:WP_032941992	DNA topoisomerase III [Bacteroides massiliensis].	26.09	575	349	19	7	531	2	550	3e-41	169
tr:A0A0A8W477_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.34	554	342	21	7	543	5	520	3e-41	168
rs:WP_041080612	DNA topoisomerase III [Bifidobacterium longum].	26.02	561	361	14	7	539	4	538	3e-41	169
rs:WP_023251690	DNA topoisomerase III, partial [Salmonella enterica].	32.58	310	197	7	251	552	2	307	3e-41	164
rs:WP_026504229	DNA topoisomerase III [Butyrivibrio sp. NC3005].	25.90	614	385	17	5	553	4	612	3e-41	168
rs:WP_032575783	DNA topoisomerase I [Bacteroides fragilis].	25.97	616	393	20	4	591	1	581	3e-41	168
rs:WP_005642341	DNA topoisomerase I [Parabacteroides merdae].	25.08	602	409	15	4	591	1	574	3e-41	168
rs:WP_043567723	DNA topoisomerase III [Candidatus Accumulibacter sp. BA-93].	28.64	583	349	21	7	550	6	560	3e-41	170
rs:WP_028298222	DNA topoisomerase III [Olivibacter sitiensis].	27.37	537	346	15	8	531	5	510	3e-41	168
rs:WP_004460131	DNA topoisomerase III [Clostridium perfringens].	30.04	566	341	18	7	550	5	537	3e-41	168
rs:WP_002316086	DNA topoisomerase [Enterococcus faecium].	29.55	467	287	13	108	556	1	443	3e-41	167
rs:WP_002610336	MULTISPECIES: DNA topoisomerase III [Firmicutes].	27.99	568	342	17	7	550	4	528	3e-41	168
tr:F7JS33_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.85	499	326	13	7	491	4	472	3e-41	166
rs:WP_008268666	DNA topoisomerase [Enterococcus sp. GMD1E].	29.55	467	287	13	108	556	1	443	3e-41	167
rs:WP_028087700	DNA topoisomerase III [Dorea longicatena].	26.37	603	379	18	8	554	7	600	3e-41	168
rs:WP_036812954	DNA topoisomerase III [Polaromonas sp. CG9_12].	26.58	617	363	20	5	550	3	600	3e-41	171
rs:WP_015395978	DNA topoisomerase III [Candidatus Kinetoplastibacterium desouzaii].	26.81	593	376	15	7	568	6	571	3e-41	169
tr:U2QF86_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.55	467	287	13	108	556	1	443	3e-41	167
rs:WP_034947418	DNA topoisomerase III [Candidatus Accumulibacter sp. SK-02].	27.65	575	365	17	7	550	6	560	3e-41	170
rs:WP_044159254	DNA topoisomerase I [Bacteroides reticulotermitis].	29.91	468	285	18	97	550	35	473	3e-41	167
tr:X8ID75_9FUSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.74	584	368	21	7	573	4	550	3e-41	168
rs:WP_008271225	MULTISPECIES: DNA topoisomerase [Enterococcus].	29.55	467	287	13	108	556	1	443	3e-41	167
rs:WP_032532598	DNA topoisomerase I [Bacteroides fragilis].	26.75	572	360	18	4	552	1	536	3e-41	168
tr:W4UM81_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	29.91	468	285	18	97	550	50	488	3e-41	168
rs:WP_001235758	DNA topoisomerase III [Escherichia coli].	28.14	565	363	16	7	544	4	552	3e-41	168
rs:WP_035021888	DNA topoisomerase III [Carnobacterium sp. WN1374].	25.95	555	353	16	5	550	3	508	4e-41	168
rs:WP_029729038	DNA topoisomerase I [Elizabethkingia anophelis].	28.50	572	352	19	4	552	1	538	4e-41	168
tr:W4V0T6_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.47	563	362	18	8	550	5	535	4e-41	167
rs:WP_044955363	DNA topoisomerase III, partial [Lachnospiraceae bacterium 1_4_56FAA].	25.85	499	326	13	7	491	4	472	4e-41	166
rs:WP_003525508	DNA topoisomerase III [[Clostridium] clostridioforme].	26.98	567	353	16	3	550	2	526	4e-41	168
rs:WP_015058978	Topo3 [Escherichia coli].	28.32	565	362	16	7	544	4	552	4e-41	168
rs:WP_003813716	DNA topoisomerase III [Bifidobacterium bifidum].	26.81	593	349	21	7	549	4	561	4e-41	168
rs:WP_034440685	DNA topoisomerase [Clostridiales bacterium S5-A11].	25.61	613	396	19	7	606	4	569	4e-41	167
rs:WP_006829051	DNA topoisomerase III [Planococcus antarcticus].	28.39	560	351	18	7	544	5	536	4e-41	168
rs:WP_019035605	DNA topoisomerase III [Prevotella amnii].	27.24	558	344	17	8	531	5	534	4e-41	167
rs:WP_047211613	DNA topoisomerase [Streptococcus agalactiae].	26.07	610	393	21	7	604	4	567	4e-41	167
tr:A0A0A8W8B0_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.88	554	339	21	7	543	5	520	4e-41	168
rs:WP_022453611	DNA topoisomerase [Prevotella sp. CAG:873].	27.25	510	327	12	63	550	1	488	4e-41	167
rs:WP_004278181	DNA topoisomerase III [Campylobacter upsaliensis].	27.35	574	355	20	4	546	1	543	4e-41	168
rs:WP_002370359	DNA topoisomerase III, partial [Enterococcus faecalis].	28.29	516	306	19	1	496	1	472	4e-41	166
rs:WP_012908954	DNA topoisomerase III [Citrobacter rodentium].	28.14	565	363	16	7	544	4	552	4e-41	168
rs:WP_021348945	hypothetical protein [Elizabethkingia meningoseptica].	28.50	572	352	19	4	552	1	538	4e-41	168
rs:WP_002338064	DNA topoisomerase III [Enterococcus faecium].	29.34	467	288	13	108	556	1	443	4e-41	167
rs:WP_032837319	DNA topoisomerase [Fusobacterium sp. CM1].	27.74	584	368	21	7	573	8	554	4e-41	168
tr:D0TV73_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	28.76	525	320	18	48	550	3	495	4e-41	167
rs:WP_034319070	DNA topoisomerase III, partial [Helicobacter trogontum].	25.76	594	373	18	8	559	5	572	4e-41	167
rs:WP_033655545	DNA topoisomerase, partial [Enterococcus faecium].	29.41	510	322	16	5	494	3	494	4e-41	166
tr:H1DE94_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EHP49991.1};	27.67	571	350	18	7	550	6	540	4e-41	168
rs:WP_035639814	hypothetical protein, partial [Lachnospiraceae bacterium ND2006].	27.84	582	372	19	8	553	7	576	4e-41	167
tr:A0A061NAW1_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.91	576	358	19	43	599	29	560	4e-41	168
rs:WP_036665367	DNA topoisomerase III [Paenibacillus sp. FSL H8-457].	26.27	628	396	19	5	599	3	596	4e-41	168
rs:WP_024235642	DNA topoisomerase III [Escherichia coli].	28.07	570	357	17	7	544	4	552	4e-41	168
rs:WP_043036435	DNA topoisomerase [Streptococcus equi].	27.89	563	346	16	5	553	3	519	4e-41	167
rs:WP_044188344	ATP-dependent DNA helicase RecQ [Hyalangium minutum].	25.21	587	362	18	2	531	32	598	4e-41	171
tr:M5U4I0_9PLAN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.38	577	364	18	3	553	9	556	4e-41	169
rs:WP_034688920	DNA topoisomerase III [Enterococcus mundtii].	26.84	529	312	19	41	550	1	473	4e-41	167
tr:Q1DEW9_MYXXD	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.12	582	354	17	7	531	1	563	4e-41	171
rs:WP_002311029	DNA topoisomerase [Enterococcus faecium].	29.60	446	273	12	108	536	1	422	4e-41	166
rs:WP_034932201	DNA topoisomerase III [Candidatus Accumulibacter sp. SK-12].	28.23	581	354	20	7	550	6	560	4e-41	169
tr:A0A0C7LW27_CLOSO	SubName: Full=TopA_3 protein {ECO:0000313|EMBL:CEP45829.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEP45829.1};	28.16	554	343	21	7	543	5	520	5e-41	168
rs:WP_032106904	DNA topoisomerase III, partial [Escherichia coli].	32.58	310	197	7	251	552	8	313	5e-41	164
rs:WP_038695639	DNA topoisomerase I [Sphingobacterium sp. ML3W].	26.52	626	395	19	4	598	1	592	5e-41	168
rs:WP_005874605	DNA topoisomerase I [Porphyromonas gingivalis].	26.57	557	335	18	7	531	4	518	5e-41	168
rs:WP_039920388	DNA topoisomerase [Anaerococcus vaginalis].	25.94	613	394	20	7	606	4	569	5e-41	167
rs:WP_001550443	DNA topoisomerase III family protein [Escherichia coli].	28.42	570	355	18	7	544	4	552	5e-41	168
rs:WP_026706431	DNA topoisomerase I [Flavobacterium soli].	28.24	556	333	21	4	531	1	518	5e-41	168
rs:WP_032180613	DNA topoisomerase III [Escherichia coli].	28.25	570	356	17	7	544	4	552	5e-41	168
rs:WP_040611578	DNA topoisomerase I [Odoribacter laneus].	27.67	571	350	18	7	550	4	538	5e-41	168
rs:WP_021900326	DNA topoisomerase [Eggerthella sp. CAG:1427].	27.83	557	353	17	4	543	1	525	5e-41	168
rs:WP_031485737	DNA topoisomerase I [Desulfovibrio frigidus].	26.21	618	415	17	7	602	4	602	5e-41	168
rs:WP_024854553	DNA topoisomerase III [[Ruminococcus] gnavus].	26.77	594	370	19	8	554	7	582	5e-41	167
tr:C7HSY0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.94	613	394	20	7	606	8	573	5e-41	167
rs:WP_007884408	DNA topoisomerase III [Roseburia inulinivorans].	26.51	562	357	14	7	550	4	527	5e-41	167
rs:WP_026161838	DNA topoisomerase I [Porphyromonas somerae].	26.44	571	357	17	5	552	3	533	5e-41	167
rs:WP_021633201	DNA topoisomerase [Clostridium sp. ATCC BAA-442].	27.80	554	338	18	7	546	4	509	5e-41	167
rs:WP_028309380	DNA topoisomerase III [Desulfitibacter alkalitolerans].	27.19	548	346	15	7	538	4	514	5e-41	167
rs:WP_010723882	DNA topoisomerase III [Enterococcus faecium].	29.34	467	288	13	108	556	1	443	5e-41	167
rs:WP_016324269	DNA topoisomerase III [Oscillibacter sp. 1-3].	26.18	550	352	16	7	539	7	519	5e-41	167
rs:WP_032880430	DNA topoisomerase [Fusobacterium nucleatum].	27.74	584	368	21	7	573	8	554	5e-41	167
rs:WP_034860927	DNA topoisomerase III [Enterococcus faecalis].	25.92	517	327	16	43	550	1	470	5e-41	167
rs:WP_001503703	DNA topoisomerase III family protein, partial [Escherichia coli].	28.25	570	356	17	7	544	4	552	5e-41	167
rs:WP_033946171	DNA topoisomerase III [Pseudomonas aeruginosa].	25.58	606	396	15	7	573	4	593	5e-41	168
rs:WP_007052706	DNA topoisomerase III [Bifidobacterium longum].	25.85	561	362	14	7	539	4	538	5e-41	168
tr:Q19V32_HAEIF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.90	423	269	13	7	406	4	413	5e-41	164
rs:WP_002205096	DNA topoisomerase I [Bacillus cereus].	26.43	628	395	17	5	599	4	597	5e-41	169
rs:WP_005549947	DNA topoisomerase III [Paenibacillus alvei].	26.11	651	394	23	5	600	3	621	5e-41	168
rs:WP_023156604	DNA topoisomerase [Escherichia coli].	28.42	570	355	18	7	544	4	552	5e-41	168
rs:WP_022110771	DNA topoisomerase III [Prevotella sp. CAG:604].	26.90	580	334	20	7	531	2	546	5e-41	168
rs:WP_039446882	DNA topoisomerase I [Porphyromonas gulae].	26.23	549	344	15	7	531	5	516	6e-41	167
rs:WP_023924313	DNA topoisomerase III [[Ruminococcus] gnavus].	26.59	598	366	19	8	554	7	582	6e-41	167
rs:WP_005861699	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	26.82	604	385	20	4	592	1	562	6e-41	167
rs:WP_023519206	DNA topoisomerase III, partial [Enterococcus mundtii].	26.43	526	318	18	41	550	1	473	6e-41	167
rs:WP_044925917	DNA topoisomerase III [[Ruminococcus] obeum].	25.92	625	383	20	7	603	4	576	6e-41	167
rs:WP_021127600	DNA topoisomerase III [[Clostridium] sordellii].	28.16	554	343	21	7	543	5	520	6e-41	167
rs:WP_032331421	DNA topoisomerase III [Escherichia coli].	28.57	567	361	18	7	546	4	553	6e-41	167
rs:WP_036865053	DNA topoisomerase I [Porphyromonas sp. COT-108 OH2963].	26.31	555	342	16	4	531	2	516	6e-41	167
rs:WP_037450141	DNA topoisomerase III [Skermanella stibiiresistens].	27.62	601	352	20	5	561	3	564	6e-41	167
tr:T0VIC8_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.62	586	360	20	33	603	9	539	6e-41	167
rs:WP_008693641	type I topoisomease [Fusobacterium nucleatum].	27.74	584	368	21	7	573	8	554	6e-41	167
tr:U7TAX9_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.74	584	368	21	7	573	4	550	6e-41	167
rs:WP_004461109	DNA topoisomerase III [Clostridium perfringens].	28.47	562	355	18	7	550	5	537	6e-41	167
rs:WP_039836735	DNA topoisomerase III, partial [Paenibacillus sonchi].	25.77	613	383	18	5	580	3	580	6e-41	167
rs:WP_029437123	DNA topoisomerase I [Bacillus thuringiensis].	26.77	609	381	17	5	583	4	577	6e-41	169
rs:WP_021026750	DNA topoisomerase III [Comamonas sp. B-9].	26.93	609	377	20	3	568	2	585	6e-41	169
rs:WP_036863984	MULTISPECIES: DNA topoisomerase I [Prevotella].	26.32	551	346	15	4	531	2	515	6e-41	167
rs:WP_008124769	DNA topoisomerase I [Prevotella timonensis].	26.50	551	345	16	4	531	2	515	6e-41	167
rs:WP_015734703	DNA topoisomerase III [Paenibacillus sp. Y412MC10].	26.27	628	396	19	5	599	3	596	6e-41	168
rs:WP_040949651	DNA topoisomerase III, partial [Paenibacillaceae bacterium G5].	26.69	577	339	16	5	532	3	544	6e-41	166
rs:WP_038281769	DNA topoisomerase III [[Clostridium] celerecrescens].	26.02	611	355	22	8	532	7	606	7e-41	167
rs:WP_021533550	hypothetical protein [Escherichia coli].	28.25	570	356	17	7	544	4	552	7e-41	167
tr:F7M0K7_9BACE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN09098.1};	26.57	572	361	19	4	552	2	537	7e-41	167
rs:WP_005809261	DNA topoisomerase I [Bacteroides fragilis].	25.37	603	395	16	4	592	1	562	7e-41	167
rs:WP_032904947	DNA topoisomerase III [Yersinia enterocolitica].	28.49	558	346	17	7	532	4	540	7e-41	167
rs:WP_021534058	hypothetical protein [Escherichia coli].	28.07	570	357	17	7	544	4	552	7e-41	167
rs:WP_010249847	DNA topoisomerase [Myroides injenensis].	26.32	570	365	15	4	552	1	536	7e-41	167
tr:U7T468_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.01	557	349	19	7	550	4	521	7e-41	167
rs:WP_036638054	DNA topoisomerase III [Paenibacillus sp. FSL R5-808].	26.14	635	390	20	5	599	3	598	7e-41	168
rs:WP_028597698	DNA topoisomerase III [Paenibacillus pasadenensis].	26.10	636	401	21	5	600	3	609	7e-41	168
rs:WP_025001427	DNA topoisomerase I [Prevotella aurantiaca].	25.82	550	348	15	5	531	3	515	7e-41	167
rs:WP_001423372	DNA topoisomerase III family protein [Escherichia coli].	28.42	570	355	17	7	544	4	552	7e-41	167
rs:WP_008246963	DNA topoisomerase III [Limnobacter sp. MED105].	27.22	551	356	16	7	531	10	541	7e-41	169
rs:WP_031884038	DNA topoisomerase III [Staphylococcus aureus].	28.47	548	347	18	5	531	3	526	7e-41	167
rs:WP_041937893	DNA topoisomerase III, partial [Klebsiella pneumoniae].	27.51	618	382	19	7	579	4	600	7e-41	167
tr:U5N7W5_9BURK	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AGX87651.1};	25.40	622	386	20	5	568	8	609	7e-41	169
rs:WP_046535048	DNA topoisomerase III [Candidatus Accumulibacter phosphatis].	27.65	575	365	17	7	550	6	560	7e-41	169
tr:W1AZV1_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.58	310	197	7	251	552	31	336	7e-41	164
tr:A0A0D1K8U8_9LACT	SubName: Full=TopB_3 protein {ECO:0000313|EMBL:KIU21474.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIU21474.1};	29.83	466	288	14	5	452	3	447	7e-41	165
rs:WP_032201902	DNA topoisomerase III [Escherichia coli].	28.25	570	356	17	7	544	4	552	7e-41	167
rs:WP_021544332	hypothetical protein [Escherichia coli].	28.42	570	355	17	7	544	4	552	7e-41	167
gp:HE577054_2591	DNA topoisomerase III [Paenibacillus polymyxa M1]	25.36	627	403	19	5	599	6	599	7e-41	168
rs:WP_010736168	DNA topoisomerase III, partial [Enterococcus mundtii].	26.43	526	318	18	41	550	1	473	7e-41	167
rs:WP_021548626	hypothetical protein [Escherichia coli].	28.22	613	392	21	7	590	4	597	7e-41	167
rs:WP_047287793	DNA topoisomerase III [Bifidobacterium bifidum].	26.57	591	353	20	7	549	4	561	7e-41	167
rs:WP_019977041	DNA topoisomerase [Empedobacter brevis].	28.16	561	327	19	4	531	1	518	7e-41	167
rs:WP_036850011	DNA topoisomerase I [Porphyromonas cangingivalis].	25.00	632	409	18	4	602	1	600	7e-41	167
rs:WP_008701260	DNA topoisomerase III [Fusobacterium nucleatum].	27.93	555	352	19	7	550	8	525	7e-41	167
rs:WP_016231999	DNA topoisomerase III [Escherichia coli].	28.60	570	354	18	7	544	4	552	7e-41	167
rs:WP_011869699	DNA topoisomerase III [Herminiimonas arsenicoxydans].	28.94	577	353	21	5	550	4	554	8e-41	169
rs:WP_016290959	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	26.45	552	351	17	7	539	5	520	8e-41	167
rs:WP_035642014	DNA topoisomerase III [Lachnospiraceae bacterium FE2018].	24.20	657	382	21	1	553	1	645	8e-41	167
rs:WP_033552208	DNA topoisomerase III [Escherichia coli].	28.42	570	355	18	7	544	4	552	8e-41	167
rs:WP_034110802	DNA topoisomerase III, partial [Comamonadaceae bacterium BICA1-1].	27.18	596	365	23	2	550	4	577	8e-41	169
rs:WP_036117316	DNA topoisomerase III [Lysinibacillus sphaericus].	27.10	594	343	20	7	556	6	553	8e-41	167
rs:WP_002328357	DNA topoisomerase III [Enterococcus faecium].	29.48	441	270	12	108	531	1	417	8e-41	165
rs:WP_029397051	DNA topoisomerase III [Escherichia coli].	28.42	570	355	17	7	544	4	552	8e-41	167
rs:WP_001235762	DNA topoisomerase III [Escherichia coli].	28.42	570	355	17	7	544	4	552	8e-41	167
rs:WP_041193372	DNA topoisomerase III [Candidatus Symbiobacter mobilis].	25.40	622	386	20	5	568	3	604	8e-41	169
rs:WP_008782576	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	26.25	602	391	17	4	592	1	562	8e-41	167
rs:WP_032843340	DNA topoisomerase I [Bacteroides ovatus].	26.62	571	362	17	4	552	1	536	8e-41	167
rs:WP_045533713	DNA topoisomerase III, partial [Comamonadaceae bacterium A1].	27.01	596	366	22	2	550	4	577	8e-41	169
rs:WP_002343079	DNA topoisomerase III [Enterococcus faecium].	29.34	467	288	13	108	556	1	443	8e-41	166
rs:WP_036705368	DNA topoisomerase III, partial [Paenibacillus graminis].	25.54	607	392	17	5	580	3	580	8e-41	167
rs:WP_043886117	DNA topoisomerase III [Paenibacillus polymyxa].	25.36	627	403	19	5	599	3	596	8e-41	168
tr:A0A060NIK4_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.01	596	366	22	2	550	6	579	8e-41	169
tr:A4JV87_BURVG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.27	594	371	18	7	567	6	571	8e-41	168
rs:WP_046112814	DNA topoisomerase III [Aquincola tertiaricarbonis].	28.80	566	340	20	7	531	6	549	8e-41	169
rs:WP_006151577	DNA topoisomerase [Streptococcus infantis].	26.83	559	344	17	4	544	2	513	8e-41	165
rs:WP_044344485	DNA topoisomerase III [Escherichia coli].	28.25	570	356	17	7	544	4	552	8e-41	167
rs:WP_040072224	DNA topoisomerase III [Escherichia coli].	28.25	570	356	17	7	544	4	552	8e-41	167
rs:WP_021526654	hypothetical protein [Escherichia coli].	28.42	570	355	17	7	544	4	552	8e-41	167
rs:WP_010688141	DNA topoisomerase III [Lactobacillus animalis].	28.14	558	320	22	7	544	5	501	8e-41	167
rs:WP_036716163	DNA topoisomerase III, partial [Paenibacillus darwinianus].	24.61	634	404	18	5	599	3	601	8e-41	167
rs:WP_044302118	DNA topoisomerase [Rhodopirellula sallentina].	27.60	576	362	18	4	553	1	547	8e-41	168
rs:WP_036579540	DNA topoisomerase III, partial [Paenibacillus darwinianus].	24.61	634	404	18	5	599	3	601	8e-41	167
rs:WP_035447780	DNA topoisomerase III [Lactobacillus animalis].	28.14	558	320	22	7	544	5	501	8e-41	167
rs:WP_044115448	DNA topoisomerase I [Porphyromonas sp. KLE 1280].	26.15	566	342	16	5	539	3	523	8e-41	167
rs:WP_010968273	DNA topoisomerase III [Clostridium perfringens].	28.34	561	357	16	7	550	5	537	9e-41	167
rs:WP_025674601	DNA topoisomerase III [Paenibacillus polymyxa].	25.36	627	403	19	5	599	3	596	9e-41	168
rs:WP_024236815	DNA topoisomerase III [Escherichia coli].	28.25	570	356	17	7	544	4	552	9e-41	167
rs:WP_001235749	DNA topoisomerase III [Escherichia coli].	28.42	570	355	18	7	544	4	552	9e-41	167
rs:WP_001235744	DNA topoisomerase III [Salmonella enterica].	28.42	570	355	17	7	544	4	552	9e-41	167
rs:WP_001235736	DNA topoisomerase III [Escherichia coli].	28.07	570	357	17	7	544	4	552	9e-41	167
rs:WP_024269854	DNA topoisomerase III [Clostridium perfringens].	28.34	561	357	16	7	550	5	537	9e-41	167
rs:WP_001694195	DNA topoisomerase III family protein [Escherichia coli].	28.25	570	356	17	7	544	4	552	9e-41	167
rs:WP_043293089	DNA topoisomerase III, partial [Burkholderia vietnamiensis].	27.27	594	371	18	7	567	6	571	9e-41	168
rs:WP_045756463	DNA topoisomerase I [Sphingobacterium sp. PM2-P1-29].	28.28	580	338	20	4	550	1	535	9e-41	167
rs:WP_001429160	DNA topoisomerase III family protein [Escherichia coli].	28.60	570	354	18	7	544	4	552	9e-41	167
rs:WP_015062761	MULTISPECIES: DNA topoisomerase III [Salmonella].	25.58	606	390	17	8	574	6	589	9e-41	167
rs:WP_001235750	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	28.25	570	356	17	7	544	4	552	9e-41	167
rs:WP_039052484	DNA topoisomerase III [Escherichia coli].	28.42	570	355	17	7	544	4	552	9e-41	167
rs:WP_014760411	DNA topoisomerase III [Bifidobacterium bifidum].	26.52	592	352	20	7	549	4	561	9e-41	167
rs:WP_021422174	DNA topoisomerase III [Peptoclostridium difficile].	27.64	568	344	17	7	550	4	528	9e-41	167
rs:WP_001576902	DNA topoisomerase III [Escherichia coli].	28.42	570	355	17	7	544	4	552	9e-41	167
rs:WP_016121209	DNA topoisomerase III [Bacillus cereus].	26.86	577	355	15	5	547	4	547	1e-40	169
rs:WP_045754926	DNA topoisomerase I [Sphingobacterium sp. PM2-P1-29].	27.24	624	393	21	4	598	1	592	1e-40	167
rs:WP_016128424	DNA topoisomerase III [Bacillus cereus].	27.42	558	353	13	5	539	4	532	1e-40	169
rs:WP_009016629	DNA topoisomerase I [Parabacteroides sp. D13].	25.50	604	393	15	4	592	1	562	1e-40	167
rs:WP_025883495	DNA topoisomerase I [Porphyromonas uenonis].	26.44	571	357	17	5	552	3	533	1e-40	167
rs:WP_031896211	DNA topoisomerase III [Staphylococcus aureus].	28.47	548	347	18	5	531	3	526	1e-40	167
rs:WP_027722150	DNA topoisomerase I [Desulfovibrio zosterae].	26.98	619	409	16	7	602	4	602	1e-40	167
rs:WP_027870499	DNA topoisomerase III [[Eubacterium] cellulosolvens].	26.54	599	361	18	3	532	2	590	1e-40	167
rs:WP_001401828	DNA topoisomerase III family protein [Escherichia coli].	28.25	570	356	17	7	544	4	552	1e-40	167
tr:F7LKF0_9BACE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN04413.1};	26.75	572	360	18	4	552	2	537	1e-40	167
rs:WP_021666176	DNA topoisomerase [Porphyromonas sp. oral taxon 278].	25.80	566	344	15	5	539	3	523	1e-40	167
rs:WP_025693453	DNA topoisomerase III [Escherichia coli].	28.25	570	356	17	7	544	4	552	1e-40	167
rs:WP_022150917	DNA topoisomerase III [Lachnospiraceae bacterium CAG:215].	27.52	596	357	19	5	534	4	590	1e-40	167
tr:R3TLQ7_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.98	535	337	16	24	548	1	486	1e-40	166
rs:WP_010803751	MULTISPECIES: DNA topoisomerase III [Parabacteroides].	26.58	617	405	19	4	602	1	587	1e-40	167
rs:WP_004070246	DNA topoisomerase III [Clostridium sp. ASF502].	28.04	560	331	21	7	539	4	518	1e-40	167
rs:WP_021311269	DNA topoisomerase III [Bacteroidetes bacterium oral taxon 272].	27.08	576	342	23	7	531	2	550	1e-40	167
rs:WP_006224636	DNA topoisomerase [Achromobacter piechaudii].	29.19	555	346	19	5	536	4	534	1e-40	168
rs:WP_009242248	MULTISPECIES: DNA topoisomerase III [unclassified Lachnospiraceae].	27.63	590	349	21	8	534	7	581	1e-40	166
rs:WP_034669318	MULTISPECIES: DNA topoisomerase I [Chryseobacterium].	25.80	566	370	15	4	550	1	535	1e-40	167
rs:WP_013671966	DNA topoisomerase I [Prevotella denticola].	26.06	568	360	15	5	550	3	532	1e-40	167
rs:WP_022278616	MULTISPECIES: DNA topoisomerase III [Dorea].	26.48	676	393	22	8	596	7	665	1e-40	167
rs:WP_040015482	DNA topoisomerase III, partial [Dorea formicigenerans].	26.78	676	391	25	8	596	7	665	1e-40	167
rs:WP_028068979	DNA topoisomerase I [Sphingobacterium thalpophilum].	27.10	620	377	18	4	588	1	580	1e-40	167
rs:WP_008802445	type I topoisomease [Fusobacterium nucleatum].	27.65	586	366	21	7	573	8	554	1e-40	167
rs:WP_017648563	DNA topoisomerase III [Streptococcus agalactiae].	27.43	565	345	18	4	550	2	519	1e-40	166
rs:WP_022178733	DNA topoisomerase [Firmicutes bacterium CAG:582].	26.94	605	336	21	7	555	4	558	1e-40	167
tr:A0A0D6ISH5_ALCXX	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:CKI21189.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CKI21189.1};	29.19	555	346	19	5	536	4	534	1e-40	168
rs:WP_046147969	DNA topoisomerase I [Parabacteroides goldsteinii].	25.42	594	390	14	4	584	1	554	1e-40	167
rs:WP_019036784	DNA topoisomerase I, partial [Prevotella amnii].	26.12	559	343	16	5	531	3	523	1e-40	166
rs:WP_010054218	DNA topoisomerase III [Carnobacterium maltaromaticum].	26.74	561	337	18	7	550	5	508	1e-40	166
rs:WP_042068605	DNA topoisomerase III [Escherichia coli].	28.25	570	356	17	7	544	4	552	1e-40	167
rs:WP_042978736	DNA topoisomerase I [Bacillus mycoides].	26.94	579	352	17	5	547	4	547	1e-40	168
tr:D4LZE7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.70	607	355	20	8	532	7	599	1e-40	167
rs:WP_008675430	DNA topoisomerase I [Bacteroides sp. 9_1_42FAA].	26.64	563	366	16	7	552	5	537	1e-40	167
rs:WP_000779866	DNA topoisomerase III [Streptococcus agalactiae].	25.70	611	394	20	7	604	4	567	1e-40	166
rs:WP_001478770	DNA topoisomerase III family protein [Escherichia coli].	28.42	570	355	18	7	544	4	552	1e-40	167
rs:WP_001235742	DNA topoisomerase III [Escherichia coli].	28.73	557	344	18	7	531	4	539	1e-40	167
rs:WP_032346759	DNA topoisomerase III [Escherichia coli].	28.07	570	357	17	7	544	4	552	1e-40	167
tr:J2T8C6_9FLAO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJL74342.1};	25.80	566	370	15	4	550	25	559	1e-40	167
rs:WP_009413679	DNA topoisomerase [Capnocytophaga sp. oral taxon 326].	26.47	612	366	19	4	566	1	577	1e-40	167
tr:B0G5U8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.78	676	391	25	8	596	7	665	1e-40	167
rs:WP_017694259	MULTISPECIES: DNA topoisomerase III [Enterobacter cloacae complex].	27.94	569	364	17	8	548	5	555	1e-40	167
rs:WP_025716118	DNA topoisomerase III, partial [Paenibacillus sp. 1-18].	25.52	627	402	19	5	599	3	596	1e-40	166
tr:A5Z4Y4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.02	546	330	18	16	539	1	505	1e-40	166
rs:WP_029740844	DNA topoisomerase III, partial [Enterobacter asburiae].	27.01	522	343	15	8	509	5	508	1e-40	165
rs:WP_042098135	DNA topoisomerase III [Escherichia coli].	28.14	565	363	16	7	544	4	552	1e-40	167
rs:WP_038438416	DNA topoisomerase III [Salmonella enterica].	28.25	570	357	17	7	544	4	553	1e-40	167
rs:WP_015059104	DNA topoisomerase III [Escherichia coli].	28.25	570	356	17	7	544	4	552	1e-40	166
rs:WP_001505439	DNA topoisomerase III family protein [Escherichia coli].	28.25	570	356	17	7	544	4	552	1e-40	166
rs:WP_035234409	hypothetical protein, partial [Desulfobulbus sp. Tol-SR].	29.12	570	348	23	4	553	1	534	1e-40	166
rs:WP_025892911	DNA topoisomerase I [Bacteroides barnesiae].	26.77	564	364	15	7	552	5	537	1e-40	166
rs:WP_013671538	DNA topoisomerase I [Prevotella denticola].	26.50	551	345	15	4	531	2	515	1e-40	166
rs:WP_039428003	DNA topoisomerase I [Porphyromonas sp. COT-052 OH4946].	27.42	558	347	19	7	539	4	528	1e-40	166
rs:WP_032841868	DNA topoisomerase I [Bacteroides sp. 1_1_30].	26.40	572	362	19	4	552	1	536	1e-40	166
rs:WP_001235746	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	28.25	570	356	17	7	544	4	552	1e-40	166
tr:A0A068Z373_BIFBI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.32	593	346	23	7	549	4	561	1e-40	167
rs:WP_008783346	DNA topoisomerase III [Bifidobacterium sp. 12_1_47BFAA].	26.50	634	361	24	7	579	4	593	1e-40	167
rs:WP_023983524	hypothetical protein [Prevotella oralis].	27.01	559	363	16	4	543	1	533	1e-40	166
rs:WP_038100411	DNA topoisomerase III [Vagococcus lutrae].	26.11	517	333	13	41	550	1	475	1e-40	166
rs:WP_005336206	DNA topoisomerase III [Dorea formicigenerans].	26.48	676	393	22	8	596	7	665	1e-40	166
rs:WP_018968449	DNA topoisomerase I [Prevotella loescheii].	26.22	572	356	16	4	550	2	532	1e-40	166
rs:WP_032195778	DNA topoisomerase III [Escherichia coli].	28.25	570	356	17	7	544	4	552	1e-40	166
rs:WP_028898404	DNA topoisomerase I [Prevotella sp. HUN102].	24.53	632	412	19	4	602	1	600	1e-40	166
rs:WP_036666677	DNA topoisomerase III, partial [Paenibacillus darwinianus].	24.61	634	404	18	5	599	3	601	1e-40	166
rs:WP_025018050	DNA topoisomerase III [Bacteroides sartorii].	26.36	569	355	19	7	531	2	550	1e-40	166
rs:WP_033560648	DNA topoisomerase III [Escherichia coli].	28.42	570	355	17	7	544	4	552	2e-40	166
tr:J9C5L9_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJW95125.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EJW95125.1};	26.88	573	340	19	7	531	2	543	2e-40	166
rs:WP_027952894	DNA topoisomerase I [Hallella seregens].	25.43	633	405	19	4	602	1	600	2e-40	166
rs:WP_006531800	DNA topoisomerase [Streptococcus infantarius].	25.61	617	400	18	7	607	5	578	2e-40	165
rs:WP_038810986	DNA topoisomerase [Enterococcus faecium].	29.34	467	288	13	108	556	1	443	2e-40	166
rs:WP_001235747	MULTISPECIES: DNA topoisomerase III [Gammaproteobacteria].	28.25	570	356	17	7	544	4	552	2e-40	166
rs:WP_005816781	DNA topoisomerase I [Bacteroides fragilis].	26.12	605	398	19	4	591	1	573	2e-40	166
rs:WP_016289972	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	26.87	588	365	17	1	563	1	548	2e-40	166
rs:WP_015058228	DNA topoisomerase III [Escherichia coli].	28.25	570	356	17	7	544	4	552	2e-40	166
rs:WP_022201940	DNA topoisomerase III [Clostridium clostridioforme CAG:132].	26.02	611	351	23	8	532	7	602	2e-40	166
rs:WP_006675493	DNA topoisomerase III [Paenibacillus dendritiformis].	24.68	628	406	18	5	599	3	596	2e-40	167
rs:WP_039890715	DNA topoisomerase III [[Clostridium] hathewayi].	26.50	566	349	18	8	550	1	522	2e-40	166
rs:WP_046617322	DNA topoisomerase III [Salmonella enterica].	28.07	570	357	17	7	544	4	552	2e-40	166
rs:WP_004845710	DNA topoisomerase III [[Ruminococcus] torques].	27.75	591	347	22	8	534	7	581	2e-40	166
rs:WP_022037158	DNA topoisomerase III [Ruminococcus gnavus CAG:126].	26.59	598	366	19	8	554	7	582	2e-40	166
rs:WP_033804686	DNA topoisomerase III [Escherichia coli].	28.25	570	356	17	7	544	4	552	2e-40	166
rs:WP_032341387	DNA topoisomerase III [Escherichia coli].	28.62	552	351	16	7	531	4	539	2e-40	166
rs:WP_021941314	DNA topoisomerase [Clostridium sp. CAG:632].	25.20	639	406	20	8	590	6	628	2e-40	166
rs:WP_037441084	DNA topoisomerase I [Sphingobacterium antarcticum].	27.24	580	344	20	4	550	1	535	2e-40	166
rs:WP_002417647	DNA topoisomerase III [Enterococcus faecalis].	26.13	620	384	21	7	601	6	576	2e-40	166
rs:WP_021526210	hypothetical protein [Escherichia coli].	28.25	570	356	17	7	544	4	552	2e-40	166
rs:WP_003817179	DNA topoisomerase III [Bifidobacterium bifidum].	27.56	595	342	24	7	549	4	561	2e-40	166
rs:WP_032509776	DNA topoisomerase III [Peptoclostridium difficile].	27.69	567	345	16	7	550	4	528	2e-40	166
rs:WP_035476679	hypothetical protein [Burkholderia phenoliruptrix].	28.27	474	303	18	6	460	5	460	2e-40	164
rs:WP_001235760	DNA topoisomerase III [Escherichia coli].	27.64	568	362	15	7	544	4	552	2e-40	166
rs:WP_001235752	DNA topoisomerase III [Salmonella enterica].	28.25	570	356	17	7	544	4	552	2e-40	166
rs:WP_023893457	DNA topoisomerase III [Salmonella enterica].	25.37	603	395	17	8	574	6	589	2e-40	167
rs:WP_032181595	DNA topoisomerase III [Escherichia coli].	28.25	570	356	17	7	544	4	552	2e-40	166
rs:WP_033798032	DNA topoisomerase III, partial [Bacillus mycoides].	33.62	354	205	12	213	548	17	358	2e-40	165
tr:A0A0C7LRN9_CLOSO	SubName: Full=TopA_2 protein {ECO:0000313|EMBL:CEP45728.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEP45728.1};	28.70	554	340	21	7	543	5	520	2e-40	166
rs:WP_046597968	DNA topoisomerase III [Salmonella enterica].	28.25	570	356	17	7	544	4	552	2e-40	166
rs:WP_033584657	DNA topoisomerase [Streptococcus sp. SR1].	26.37	565	351	17	4	550	2	519	2e-40	165
rs:WP_004366614	DNA topoisomerase I [Prevotella nigrescens].	25.12	633	407	19	4	602	1	600	2e-40	166
rs:WP_036872688	DNA topoisomerase I [Porphyromonas macacae].	27.64	568	353	19	7	550	4	537	2e-40	166
rs:WP_020956887	DNA topoisomerase [Klebsiella pneumoniae].	27.51	618	382	19	7	579	4	600	2e-40	167
rs:WP_006286037	topoisomerase IA [Paenibacillus popilliae].	25.00	628	404	19	5	599	3	596	2e-40	166
rs:WP_025487227	DNA topoisomerase III [Clostridiales bacterium VE202-28].	25.43	641	380	21	8	570	7	627	2e-40	166
rs:WP_044796831	DNA topoisomerase I [Bacillus cereus].	26.17	577	359	15	5	547	4	547	2e-40	167
rs:WP_000237218	DNA topoisomerase III [Streptococcus sp. oral taxon 071].	25.94	559	361	15	4	550	2	519	2e-40	165
rs:WP_024139110	DNA topoisomerase III [Salmonella enterica].	25.37	603	395	17	8	574	6	589	2e-40	166
rs:WP_016770543	DNA topoisomerase [Salmonella enterica].	28.07	570	357	17	7	544	4	552	2e-40	166
rs:WP_001235753	DNA topoisomerase III [Salmonella enterica].	28.25	570	356	17	7	544	4	552	2e-40	166
rs:WP_001235745	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	28.25	570	356	17	7	544	4	552	2e-40	166
rs:WP_031653319	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	32.33	300	182	7	8	301	5	289	2e-40	159
rs:WP_016359326	DNA topoisomerase III [Pseudomonas fluorescens].	26.68	566	352	17	7	532	4	546	2e-40	166
rs:WP_009272259	DNA topoisomerase III [Erysipelotrichaceae bacterium 3_1_53].	26.27	552	361	16	5	531	3	533	2e-40	166
rs:WP_012859159	DNA topoisomerase [Streptobacillus moniliformis].	27.74	548	335	19	7	540	4	504	2e-40	166
rs:WP_007520053	DNA topoisomerase III [Streptococcus tigurinus].	26.25	560	358	15	4	550	2	519	2e-40	165
rs:WP_031417620	DNA topoisomerase III [Lysinibacillus sphaericus].	28.42	570	353	20	7	548	5	547	2e-40	166
rs:WP_002981562	DNA topoisomerase [Chryseobacterium gleum].	26.62	571	363	20	4	552	1	537	2e-40	166
rs:WP_004192797	DNA topoisomerase III [Klebsiella pneumoniae].	27.77	569	365	17	8	548	5	555	2e-40	166
rs:WP_025370412	hypothetical protein [Campylobacter fetus].	25.93	567	379	17	8	553	5	551	2e-40	166
rs:WP_014709363	DNA topoisomerase I [Prevotella intermedia].	25.12	633	407	19	4	602	1	600	2e-40	166
tr:D3ABL1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	26.50	566	349	18	8	550	1	522	2e-40	166
rs:WP_001235756	DNA topoisomerase III [Escherichia coli].	28.07	570	357	17	7	544	4	552	2e-40	166
rs:WP_021069091	transposase [Sphingobacterium paucimobilis].	27.01	559	346	15	4	531	1	528	2e-40	166
rs:WP_028102328	DNA topoisomerase III [Pseudoduganella violaceinigra].	28.65	569	361	20	7	550	6	554	2e-40	167
rs:WP_046602256	DNA topoisomerase III [Pseudomonas aeruginosa].	26.07	606	392	16	8	573	5	594	2e-40	166
rs:WP_013520941	DNA topoisomerase III [Alicycliphilus denitrificans].	27.66	611	366	22	5	568	4	585	2e-40	168
rs:WP_044976667	hypothetical protein [Ruminococcus sp. HUN007].	29.08	588	344	19	4	550	1	556	2e-40	166
rs:WP_029463186	DNA topoisomerase III, partial [Comamonadaceae bacterium H1].	27.27	594	367	21	2	550	4	577	2e-40	168
rs:WP_019208345	DNA topoisomerase III [Phocaeicola abscessus].	27.08	576	342	23	7	531	2	550	2e-40	166
rs:WP_007365528	DNA topoisomerase I [Porphyromonas uenonis].	26.76	568	355	17	5	550	3	531	2e-40	166
rs:WP_023052298	hypothetical protein [Cetobacterium somerae].	25.69	689	404	21	7	606	4	673	2e-40	166
rs:WP_008799063	type I topoisomease [Fusobacterium nucleatum].	27.65	586	366	21	7	573	8	554	2e-40	166
rs:WP_032496642	MULTISPECIES: DNA topoisomerase I [Bacteroides].	26.57	572	361	18	4	552	1	536	2e-40	166
rs:WP_019561538	DNA topoisomerase III [Caldimonas manganoxidans].	27.53	603	371	23	7	567	6	584	2e-40	167
tr:A0A078SW41_9PORP	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:KDS64711.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KDS64711.1};	26.67	570	359	18	4	550	2	535	2e-40	166
rs:WP_004842675	DNA topoisomerase III [[Ruminococcus] gnavus].	26.59	598	366	19	8	554	7	582	2e-40	166
rs:WP_039422551	DNA topoisomerase I [Porphyromonas gulae].	25.28	633	406	19	4	602	1	600	2e-40	166
rs:WP_007860201	hypothetical protein [[Clostridium] citroniae].	25.81	558	363	16	7	550	4	524	2e-40	166
rs:WP_001235767	DNA topoisomerase III [Escherichia coli].	27.89	570	358	17	7	544	4	552	2e-40	166
rs:WP_047298255	DNA topoisomerase III [Bifidobacterium bifidum].	27.15	593	347	23	7	549	4	561	2e-40	166
rs:WP_045853554	DNA topoisomerase III [Raoultella terrigena].	28.70	575	361	20	8	552	5	560	2e-40	166
rs:WP_022759902	DNA topoisomerase III [Butyrivibrio sp. AD3002].	27.02	607	376	19	5	554	4	600	2e-40	166
rs:WP_032569313	DNA topoisomerase I [Bacteroides fragilis].	25.62	605	401	18	4	591	1	573	2e-40	166
rs:WP_039416653	DNA topoisomerase I [Porphyromonas gingivalis].	27.32	560	327	22	7	531	4	518	2e-40	166
rs:WP_042266884	DNA topoisomerase III [Paenibacillus graminis].	25.54	607	392	17	5	580	3	580	2e-40	166
rs:WP_004371701	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	26.87	603	384	20	4	591	1	561	2e-40	166
rs:WP_029485981	DNA topoisomerase [Enterococcus faecium].	29.12	467	289	13	108	556	1	443	2e-40	165
rs:WP_019533739	DNA topoisomerase III [Paenibacillus ginsengihumi].	25.36	631	401	19	5	599	3	599	3e-40	167
rs:WP_029473397	DNA topoisomerase III [Clostridiales bacterium VE202-08].	25.09	558	371	12	5	539	3	536	3e-40	166
rs:WP_001241818	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	27.77	569	365	17	8	548	5	555	3e-40	166
rs:WP_001235740	DNA topoisomerase III [Escherichia coli].	28.42	570	355	18	7	544	4	552	3e-40	166
rs:WP_046504073	DNA topoisomerase III [Paenibacillus riograndensis].	25.54	607	392	17	5	580	3	580	3e-40	166
rs:WP_032666425	DNA topoisomerase III [Enterobacter cloacae].	28.12	569	363	17	8	548	5	555	3e-40	166
rs:WP_003045441	DNA topoisomerase III [Streptococcus canis].	26.43	575	355	18	5	561	3	527	3e-40	164
rs:WP_028913321	DNA topoisomerase III [Prevotella sp. MA2016].	27.07	569	342	19	7	531	2	541	3e-40	166
rs:WP_045369874	DNA topoisomerase III [Enterobacter asburiae].	28.12	569	363	17	8	548	5	555	3e-40	166
rs:WP_023281073	hypothetical protein [Escherichia coli].	27.77	569	365	17	8	548	5	555	3e-40	166
rs:WP_008716160	DNA topoisomerase III [Clostridiales bacterium 1_7_47FAA].	26.00	600	357	19	8	532	7	594	3e-40	166
rs:WP_026497541	DNA topoisomerase III [Butyrivibrio sp. WCD2001].	26.64	608	378	19	5	554	4	601	3e-40	165
rs:WP_001714225	DNA topoisomerase III [Salmonella enterica].	28.25	570	356	17	7	544	4	552	3e-40	166
rs:WP_000237215	DNA topoisomerase III [Streptococcus agalactiae].	27.26	565	346	18	4	550	2	519	3e-40	164
rs:WP_025577921	DNA topoisomerase III [Blautia wexlerae].	28.94	508	301	17	7	491	4	474	3e-40	163
rs:WP_001235754	DNA topoisomerase III [Salmonella enterica].	28.07	570	357	17	7	544	4	552	3e-40	166
rs:WP_021912630	DNA topoisomerase [Eubacterium sp. CAG:786].	26.78	575	358	15	7	556	4	540	3e-40	166
rs:WP_001235741	DNA topoisomerase III [Escherichia coli].	28.42	570	355	18	7	544	4	552	3e-40	166
tr:A0A085WJV1_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.13	585	361	18	4	531	1	565	3e-40	168
rs:WP_024127756	DNA topoisomerase III [Escherichia coli].	27.89	570	358	17	7	544	4	552	3e-40	166
rs:WP_001235763	DNA topoisomerase III [Escherichia coli].	28.25	570	356	17	7	544	4	552	3e-40	166
rs:WP_022309500	DNA topoisomerase III [Prevotella sp. CAG:474].	27.64	550	334	20	7	531	2	512	3e-40	165
rs:WP_020191335	hypothetical protein [Pseudomonas putida].	27.23	617	372	24	5	581	4	583	3e-40	167
rs:WP_026651907	DNA topoisomerase III [Butyrivibrio proteoclasticus].	25.99	631	379	19	1	553	1	621	3e-40	166
rs:WP_031825716	DNA topoisomerase III, partial [Staphylococcus aureus].	30.53	475	303	13	80	544	8	465	3e-40	165
rs:WP_032325884	DNA topoisomerase III [Escherichia coli].	28.27	566	361	17	7	544	4	552	3e-40	166
rs:WP_032602824	DNA topoisomerase I, partial [Bacteroides fragilis].	25.62	605	401	18	4	591	1	573	3e-40	165
rs:WP_040118784	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	27.57	584	342	16	5	547	4	547	3e-40	167
rs:WP_044074388	DNA topoisomerase III [Escherichia coli].	28.25	570	356	17	7	544	4	552	3e-40	166
rs:WP_035690956	DNA topoisomerase III [Azospirillum halopraeferens].	26.55	565	340	17	5	531	3	530	3e-40	166
rs:WP_032490885	topoisomerase [Yersinia enterocolitica].	26.53	573	357	16	43	567	36	592	3e-40	166
rs:WP_006951164	DNA topoisomerase III [Prevotella micans].	26.32	551	347	19	7	531	2	519	3e-40	164
rs:WP_001482238	DNA topoisomerase III family protein [Escherichia coli].	28.42	570	355	18	7	544	4	552	3e-40	166
rs:WP_024256650	DNA topoisomerase III [Escherichia coli].	28.42	570	355	18	7	544	4	552	3e-40	166
rs:WP_021528064	hypothetical protein [Escherichia coli].	28.07	570	357	17	7	544	4	552	3e-40	166
rs:WP_038369398	hypothetical protein [Brackiella oedipodis].	27.74	548	328	18	5	532	3	502	3e-40	165
rs:WP_000557251	DNA topoisomerase III [Streptococcus agalactiae].	27.32	560	353	15	5	553	3	519	3e-40	164
rs:WP_016731587	MULTISPECIES: DNA topoisomerase [Enterobacteriaceae].	27.64	568	362	15	7	544	4	552	3e-40	166
tr:D4K2M3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.72	539	341	16	16	539	1	500	3e-40	165
rs:WP_022076405	DNA topoisomerase III [Firmicutes bacterium CAG:212].	27.17	600	376	22	5	554	4	592	3e-40	165
rs:WP_023988966	DNA topoisomerase III [Paenibacillus polymyxa].	25.36	627	403	20	5	599	3	596	3e-40	166
rs:WP_033798183	DNA topoisomerase I [Bacillus mycoides].	27.23	584	344	17	5	547	4	547	3e-40	167
rs:WP_020373506	hypothetical protein [Sulfobacillus thermosulfidooxidans].	26.67	555	343	17	7	539	4	516	3e-40	165
rs:WP_039972488	DNA topoisomerase I [Bacteroides pyogenes].	26.98	556	334	20	7	531	4	518	3e-40	165
rs:WP_004584311	DNA topoisomerase [Porphyromonas gingivalis].	24.68	632	411	18	4	602	1	600	3e-40	165
rs:WP_029216649	DNA topoisomerase I [Prevotella denticola].	26.79	545	343	17	5	531	3	509	3e-40	165
rs:WP_013272546	DNA topoisomerase III [[Clostridium] saccharolyticum].	25.24	618	352	19	8	532	7	607	3e-40	165
rs:WP_047254498	DNA topoisomerase [Enterococcus cecorum].	26.25	560	348	17	5	539	3	522	3e-40	165
rs:WP_040118351	DNA topoisomerase III [Pectobacterium atrosepticum].	26.53	573	357	16	43	567	36	592	4e-40	166
rs:WP_023383812	DNA topoisomerase [Pseudomonas sp. VLB120].	27.44	616	372	24	5	581	4	583	4e-40	166
rs:WP_032242577	DNA topoisomerase III [Escherichia coli].	28.25	570	356	18	7	544	4	552	4e-40	165
gp:HE963029_27	DNA topoisomerase (pseudogene) [Enterococcus faecium]	25.97	620	385	21	7	601	6	576	4e-40	165
rs:WP_005802302	DNA topoisomerase I [Bacteroides fragilis].	26.49	604	387	18	4	592	1	562	4e-40	165
rs:WP_008645574	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	25.76	594	388	15	4	584	1	554	4e-40	165
rs:WP_021646279	DNA topoisomerase [Bacteroides pyogenes].	26.26	617	386	21	6	591	3	581	4e-40	165
rs:WP_007366532	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	25.04	603	407	14	4	591	1	573	4e-40	165
tr:F8K7Y7_STRPY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.48	540	349	14	7	539	8	506	4e-40	164
rs:WP_021774656	DNA topoisomerase III [Oribacterium sp. oral taxon 078].	25.43	586	391	16	7	553	5	583	4e-40	164
rs:WP_005601674	DNA topoisomerase III [Butyrivibrio crossotus].	27.35	574	347	18	3	547	2	534	4e-40	165
tr:D6BE65_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.83	574	355	16	7	548	6	546	4e-40	166
rs:WP_016110475	DNA topoisomerase III [Bacillus cereus].	26.99	578	353	16	5	547	4	547	4e-40	167
rs:WP_038699441	DNA topoisomerase I [Sphingobacterium sp. ML3W].	28.01	582	337	19	4	550	1	535	4e-40	165
rs:WP_001235738	DNA topoisomerase III [Escherichia coli].	27.88	617	389	21	7	590	4	597	4e-40	165
rs:WP_006261870	DNA topoisomerase [Myroides odoratimimus].	26.18	550	352	17	4	531	1	518	4e-40	165
rs:WP_036868643	DNA topoisomerase I [Porphyromonas canoris].	25.77	555	345	16	4	531	2	516	4e-40	165
rs:WP_001436419	DNA topoisomerase III family protein [Escherichia coli].	28.42	570	355	18	7	544	4	552	4e-40	165
rs:WP_036616528	DNA topoisomerase I [Parabacteroides distasonis].	25.76	594	388	15	4	584	1	554	4e-40	165
rs:WP_046598252	DNA topoisomerase III [Salmonella enterica].	28.07	570	357	17	7	544	4	552	4e-40	165
rs:WP_001419801	DNA topoisomerase III family protein [Escherichia coli].	27.89	570	358	17	7	544	4	552	4e-40	165
rs:WP_025140922	hypothetical protein [Achromobacter sp. DH1f].	26.47	597	362	19	35	566	4	588	4e-40	164
rs:WP_012858882	DNA topoisomerase [Streptobacillus moniliformis].	27.55	548	336	19	7	540	4	504	4e-40	165
rs:WP_032567475	DNA topoisomerase I, partial [Bacteroides fragilis].	26.10	590	388	18	18	591	3	560	4e-40	165
rs:WP_021515666	hypothetical protein [Escherichia coli].	28.07	570	357	17	7	544	4	552	4e-40	165
rs:WP_001235739	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	28.55	557	345	18	7	531	4	539	4e-40	165
tr:G2JB72_9BURK	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:CCD30025.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CCD30025.1};	28.02	464	299	16	7	452	6	452	4e-40	162
rs:WP_016247728	DNA topoisomerase III [Escherichia coli].	28.07	570	357	17	7	544	4	552	4e-40	165
rs:WP_034564290	DNA topoisomerase III [Carnobacterium gallinarum].	25.71	564	343	17	5	550	3	508	4e-40	165
rs:WP_034233149	DNA topoisomerase III [Lachnospiraceae bacterium AC2029].	26.05	622	374	20	7	554	5	614	4e-40	165
rs:WP_008979388	DNA topoisomerase III [Erysipelotrichaceae bacterium 5_2_54FAA].	26.19	569	373	16	5	548	3	549	4e-40	165
rs:WP_002360282	DNA topoisomerase, partial [Enterococcus faecium].	28.35	462	300	14	5	452	3	447	4e-40	162
rs:WP_001677783	DNA topoisomerase III family protein [Escherichia coli].	28.07	570	357	18	7	544	4	552	4e-40	165
rs:WP_027970847	DNA topoisomerase III [Streptococcus castoreus].	27.89	563	346	16	5	553	3	519	4e-40	164
rs:WP_012477155	DNA topoisomerase III [Salmonella enterica].	28.07	570	357	17	7	544	4	552	4e-40	165
rs:WP_032302216	DNA topoisomerase III [Escherichia coli].	28.19	557	347	17	7	531	4	539	4e-40	165
rs:WP_025232898	DNA topoisomerase III [Clostridium sp. ASBs410].	25.90	614	353	23	8	532	7	607	4e-40	165
rs:WP_047284460	DNA topoisomerase III [Bifidobacterium bifidum].	27.15	593	347	23	7	549	4	561	4e-40	165
rs:WP_040239386	DNA topoisomerase III, partial [Klebsiella pneumoniae].	28.66	499	312	12	74	543	6	489	4e-40	163
rs:WP_022752908	DNA topoisomerase III [Butyrivibrio fibrisolvens].	27.07	617	378	18	3	553	2	612	4e-40	165
rs:WP_035450702	DNA topoisomerase III [Lactobacillus composti].	27.50	549	333	18	3	539	2	497	4e-40	165
rs:WP_032349584	DNA topoisomerase III [Escherichia coli].	27.59	569	361	15	7	544	4	552	5e-40	165
rs:WP_045168253	DNA topoisomerase I [Prevotella intermedia].	25.12	633	407	19	4	602	1	600	5e-40	165
rs:WP_002317284	MULTISPECIES: DNA topoisomerase III [Bacteria].	25.97	620	385	21	7	601	6	576	5e-40	165
rs:WP_007430622	DNA topoisomerase III [Paenibacillus sp. Aloe-11].	25.20	631	399	19	5	599	3	596	5e-40	166
rs:WP_031842635	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	34.30	277	172	5	279	548	4	277	5e-40	159
rs:WP_033572507	DNA topoisomerase I [Bacteroides sp. UW].	26.47	578	354	19	4	552	1	536	5e-40	165
rs:WP_036889351	DNA topoisomerase I [Porphyromonas crevioricanis].	24.84	632	410	18	4	602	1	600	5e-40	165
rs:WP_022296137	DNA topoisomerase III [Firmicutes bacterium CAG:272].	27.71	563	345	20	7	550	4	523	5e-40	165
rs:WP_034568898	DNA topoisomerase III [Carnobacterium divergens].	25.70	568	338	16	5	550	3	508	5e-40	165
rs:WP_007566594	DNA topoisomerase I [Bacteroides coprocola].	28.32	572	355	20	4	550	1	542	5e-40	165
tr:A0A0E2SB13_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EXZ62045.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EXZ62045.1};	26.65	529	322	17	43	531	26	528	5e-40	165
rs:WP_008564100	DNA topoisomerase I [Prevotella maculosa].	26.77	579	359	18	4	550	1	546	5e-40	165
rs:WP_021672576	DNA topoisomerase [Prevotella sp. F0091].	25.12	633	407	19	4	602	1	600	5e-40	165
rs:WP_008687136	DNA topoisomerase III [Eubacterium sp. 3_1_31].	26.19	569	373	16	5	548	3	549	5e-40	165
rs:WP_042367709	DNA topoisomerase I [Bacteroidaceae bacterium MS4].	26.50	566	364	16	7	550	4	539	5e-40	164
rs:WP_036632665	DNA topoisomerase I [Parabacteroides distasonis].	26.36	569	362	17	4	550	1	534	5e-40	164
tr:A0A015X0P0_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EXZ04049.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EXZ04049.1};	26.65	529	322	17	43	531	26	528	5e-40	165
rs:WP_007883189	DNA topoisomerase III [Roseburia inulinivorans].	28.13	551	340	18	7	546	4	509	5e-40	164
rs:WP_002564358	MULTISPECIES: DNA topoisomerase III [Lachnoclostridium].	25.96	601	359	23	8	532	7	597	5e-40	164
rs:WP_016219894	DNA topoisomerase III [Dorea sp. 5-2].	25.47	585	372	17	7	566	4	549	5e-40	165
rs:WP_021558908	hypothetical protein [Escherichia coli].	28.37	557	346	18	7	531	4	539	5e-40	165
rs:WP_033596185	DNA topoisomerase III, partial [Enterococcus faecalis].	29.46	448	272	16	1	435	1	417	5e-40	161
rs:WP_016234218	DNA topoisomerase III [Escherichia coli].	28.50	572	355	19	7	546	4	553	5e-40	165
rs:WP_037440266	DNA topoisomerase I [Sphingobacterium antarcticum].	26.83	615	385	17	4	588	1	580	5e-40	164
tr:J4W6P3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.79	493	307	14	56	539	4	456	5e-40	163
rs:WP_003012643	DNA topoisomerase [Sphingobacterium spiritivorum].	26.40	625	384	18	4	592	1	585	5e-40	164
rs:WP_001235755	DNA topoisomerase III [Escherichia coli].	28.19	557	347	18	7	531	4	539	6e-40	165
rs:WP_011831764	DNA topoisomerase [Methylibium petroleiphilum].	28.68	551	350	17	7	536	6	534	6e-40	166
rs:WP_037298423	DNA topoisomerase III [Ruminococcus flavefaciens].	28.16	561	341	23	7	552	5	518	6e-40	164
rs:WP_029364096	DNA topoisomerase III [Escherichia coli].	28.07	570	357	17	7	544	4	552	6e-40	165
rs:WP_007195525	DNA topoisomerase III [Thiocapsa marina].	27.15	571	338	19	7	532	5	542	6e-40	166
rs:WP_045665981	hypothetical protein, partial [Pseudomonas sp. BRH_c35].	26.19	569	368	14	5	551	3	541	6e-40	164
rs:WP_044168813	DNA topoisomerase I [Porphyromonas catoniae].	25.62	566	345	15	5	539	3	523	6e-40	164
rs:WP_038994990	DNA topoisomerase III [Escherichia coli].	28.07	570	357	18	7	544	4	552	6e-40	165
rs:WP_039417014	DNA topoisomerase I [Porphyromonas gingivalis].	27.42	569	354	18	7	550	4	538	6e-40	164
rs:WP_044820516	DNA topoisomerase III [Bacteroides fragilis].	26.65	529	322	17	43	531	26	528	6e-40	164
rs:WP_002574756	DNA topoisomerase III [[Clostridium] bolteae].	25.96	601	359	23	8	532	7	597	6e-40	164
rs:WP_005944290	DNA topoisomerase III [Bacteroides massiliensis].	25.50	596	387	15	4	584	1	554	6e-40	164
rs:WP_001235748	DNA topoisomerase III [Escherichia coli].	28.32	572	356	18	7	546	4	553	6e-40	165
rs:WP_044545505	DNA topoisomerase I [Parabacteroides distasonis].	27.00	563	365	17	4	550	1	533	6e-40	164
tr:A0A084IJ21_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.91	329	202	10	1	322	12	325	6e-40	159
rs:WP_002583310	MULTISPECIES: DNA topoisomerase III [Clostridiales].	25.86	611	352	23	8	532	7	602	6e-40	164
rs:WP_016486988	MULTISPECIES: hypothetical protein [Pseudomonas putida group].	27.27	616	373	23	5	581	4	583	6e-40	166
rs:WP_003505019	DNA topoisomerase III [[Clostridium] symbiosum].	26.09	571	355	18	3	550	2	528	6e-40	164
rs:WP_021677873	DNA topoisomerase [Porphyromonas gingivalis].	26.35	554	343	15	4	531	2	516	6e-40	164
rs:WP_022146082	DNA topoisomerase [Firmicutes bacterium CAG:238].	28.04	535	326	15	48	545	41	553	6e-40	166
rs:WP_021523567	hypothetical protein [Escherichia coli].	28.07	570	357	17	7	544	4	552	6e-40	164
tr:A8RRB2_CLOBW	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.96	601	359	23	8	532	11	601	6e-40	164
rs:WP_013666927	DNA topoisomerase III [Sphingobacterium sp. 21].	26.86	566	353	19	7	543	4	537	6e-40	164
rs:WP_016284650	DNA topoisomerase III [Lachnospiraceae bacterium A4].	27.93	555	335	19	7	539	4	515	6e-40	164
rs:WP_031667774	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	26.07	606	392	16	8	573	5	594	7e-40	164
rs:WP_028298779	DNA topoisomerase I [Olivibacter sitiensis].	27.93	580	340	20	4	550	1	535	7e-40	164
rs:WP_024981683	DNA topoisomerase I [Flavobacterium succinicans].	27.21	577	358	20	7	554	4	547	7e-40	164
rs:WP_018755653	hypothetical protein [Paenibacillus terrigena].	25.81	651	396	21	5	603	3	618	7e-40	165
rs:WP_005434089	DNA topoisomerase III [Sutterella wadsworthensis].	27.52	556	349	19	3	531	2	530	7e-40	166
tr:K6AE20_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKN21946.1};	26.50	566	369	16	4	552	2	537	7e-40	164
rs:WP_040663200	DNA topoisomerase III [Oscillibacter ruminantium].	27.01	548	353	17	7	548	4	510	7e-40	164
rs:WP_024717739	MULTISPECIES: DNA topoisomerase [Pseudomonas].	27.23	617	372	24	5	581	4	583	7e-40	166
rs:WP_001701798	DNA topoisomerase III, partial [Salmonella enterica].	33.82	275	171	6	285	552	4	274	7e-40	159
rs:WP_002339858	DNA topoisomerase III [Enterococcus faecium].	28.85	468	289	13	108	556	1	443	7e-40	163
rs:WP_034028189	DNA topoisomerase III [Pseudomonas aeruginosa].	25.70	607	395	15	7	573	4	594	7e-40	164
rs:WP_022508538	DNA topoisomerase III [Bacteroides vulgatus CAG:6].	26.49	570	353	20	7	531	2	550	7e-40	164
rs:WP_005845872	DNA topoisomerase III [Bacteroides vulgatus].	26.49	570	353	20	7	531	2	550	7e-40	164
rs:WP_028856605	DNA topoisomerase III [Psychrilyobacter atlanticus].	28.85	565	335	23	7	550	5	523	8e-40	164
rs:WP_006045120	DNA topoisomerase I [Prevotella pallens].	25.83	573	357	18	4	550	2	532	8e-40	164
rs:WP_034484200	DNA topoisomerase III, partial [Butyrivibrio fibrisolvens].	27.35	618	375	20	3	553	2	612	8e-40	164
rs:WP_032361994	DNA topoisomerase III, partial [Escherichia coli].	28.01	557	348	17	7	531	4	539	8e-40	163
rs:WP_035063737	DNA topoisomerase III [Carnobacterium maltaromaticum].	26.38	561	339	18	7	550	5	508	8e-40	164
rs:WP_007836205	DNA topoisomerase III [Bacteroides dorei].	26.36	569	355	19	7	531	2	550	8e-40	164
rs:WP_009683128	DNA topoisomerase III, partial [Pseudomonas sp. TJI-51].	37.40	254	145	5	306	548	9	259	8e-40	159
rs:WP_005680137	MULTISPECIES: DNA topoisomerase I [Bacteroides].	28.80	500	307	16	72	550	2	473	8e-40	164
rs:WP_044677372	DNA topoisomerase, partial [Streptococcus suis].	28.41	521	342	17	5	509	3	508	8e-40	162
rs:WP_003207662	DNA topoisomerase I [Bacillus mycoides].	26.94	579	352	17	5	547	4	547	8e-40	166
rs:WP_001776115	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	27.77	569	365	17	8	548	5	555	8e-40	164
tr:A0A0E2RW48_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EXZ52234.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EXZ52234.1};	26.65	529	322	17	43	531	26	528	8e-40	164
rs:WP_032529718	DNA topoisomerase I [Bacteroides fragilis].	27.84	564	359	19	4	550	1	533	8e-40	164
rs:WP_002566666	DNA topoisomerase III [[Clostridium] bolteae].	26.84	570	352	19	3	550	2	528	8e-40	164
rs:WP_023662223	DNA topoisomerase [Pseudomonas taiwanensis].	27.23	617	372	24	5	581	4	583	8e-40	166
rs:WP_009228981	DNA topoisomerase I [Prevotella sp. oral taxon 299].	25.50	549	351	13	5	531	3	515	8e-40	164
rs:WP_006714456	DNA topoisomerase III [Vibrio ichthyoenteri].	26.23	549	365	14	7	532	4	535	8e-40	164
rs:WP_003562019	DNA topoisomerase III family protein [Escherichia coli].	28.25	570	356	18	7	544	4	552	8e-40	164
tr:C3QRJ0_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.80	500	307	16	72	550	19	490	8e-40	164
tr:A0A0E2SUF0_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EXZ76979.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EXZ76979.1};	26.65	529	322	17	43	531	26	528	9e-40	164
tr:F8F8M0_PAEMK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.77	623	382	20	5	590	3	594	9e-40	167
rs:WP_009268350	DNA topoisomerase III [Lachnospiraceae bacterium 1_4_56FAA].	27.18	596	359	19	5	534	4	590	9e-40	164
rs:WP_032843242	DNA topoisomerase I [Bacteroides ovatus].	28.06	563	359	19	4	550	1	533	9e-40	164
rs:WP_004346359	DNA topoisomerase I [Prevotella buccae].	27.01	548	338	19	5	531	3	509	9e-40	164
rs:WP_006255807	DNA topoisomerase I [Alloprevotella tannerae].	26.83	600	382	20	7	591	4	561	1e-39	164
tr:R2W3D4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.93	484	307	15	5	468	4	470	1e-39	161
rs:WP_046041454	topoisomerase I [Lactobacillus plantarum].	30.24	582	368	18	5	566	3	566	1e-39	164
rs:WP_009215951	DNA topoisomerase III [Oribacterium sp. oral taxon 078].	25.43	586	391	16	7	553	5	583	1e-39	163
rs:WP_001235761	DNA topoisomerase III [Escherichia coli].	28.37	557	346	18	7	531	4	539	1e-39	164
rs:WP_022282048	DNA topoisomerase [Clostridium sp. CAG:448].	27.77	587	350	21	7	551	4	558	1e-39	164
rs:WP_022197248	DNA topoisomerase III [Akkermansia muciniphila CAG:154].	27.27	583	359	21	3	548	2	556	1e-39	165
tr:A0A078R730_BACVU	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:KDS29757.1};	27.00	574	356	17	4	550	3	540	1e-39	164
rs:WP_013737914	DNA topoisomerase [Metallosphaera cuprina].	27.77	551	328	20	7	549	4	492	1e-39	164
tr:D4C6D6_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.93	505	315	15	7	491	4	474	1e-39	162
rs:WP_028897907	DNA topoisomerase I [Prevotella sp. HUN102].	27.57	544	350	16	4	531	1	516	1e-39	164
rs:WP_044930417	DNA topoisomerase III, partial [Clostridium sp. M62/1].	26.93	505	315	15	7	491	4	474	1e-39	161
rs:WP_031436385	DNA topoisomerase [Methylobacter tundripaludum].	27.89	570	337	18	4	531	1	538	1e-39	165
rs:WP_040126097	DNA topoisomerase III [Escherichia coli].	28.37	557	346	18	7	531	4	539	1e-39	164
rs:WP_001235759	DNA topoisomerase III, partial [Escherichia coli].	28.41	521	336	16	7	507	4	507	1e-39	162
rs:WP_027952609	DNA topoisomerase I [Hallella seregens].	26.58	568	339	18	5	531	3	533	1e-39	164
rs:WP_025657742	DNA topoisomerase III [Clostridiales bacterium VE202-21].	25.63	597	363	19	5	534	4	586	1e-39	164
rs:WP_035604997	DNA topoisomerase III [Haloferula sp. BvORR071].	26.88	584	357	19	7	548	6	561	1e-39	165
rs:WP_027432286	hypothetical protein [Lachnospira multipara].	29.70	468	285	13	94	540	49	493	1e-39	164
tr:A0A073IBB1_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KEJ86811.1};	26.07	560	355	17	4	539	2	526	1e-39	164
rs:WP_016270904	DNA topoisomerase III [Bacteroides vulgatus].	26.49	570	353	20	7	531	2	550	1e-39	164
rs:WP_032533104	DNA topoisomerase I [Bacteroides fragilis].	27.89	545	347	17	4	531	1	516	1e-39	164
gpu:AP013045_2147	DNA topoisomerase III [Tannerella forsythia KS16]	25.12	633	407	19	4	602	1	600	1e-39	164
rs:WP_045582666	DNA topoisomerase III [Azospirillum thiophilum].	26.30	578	343	15	5	531	3	548	1e-39	164
rs:WP_004374762	DNA topoisomerase I [Prevotella oris].	26.35	554	342	16	4	531	2	515	1e-39	164
rs:WP_005794610	DNA topoisomerase I [Bacteroides fragilis].	26.46	548	352	17	4	531	1	517	1e-39	164
rs:WP_016295429	DNA topoisomerase III [Lachnospiraceae bacterium M18-1].	27.57	555	337	19	7	539	4	515	1e-39	164
rs:WP_011965390	DNA topoisomerase III [Bacteroides vulgatus].	26.49	570	353	20	7	531	2	550	1e-39	164
rs:WP_034174036	DNA topoisomerase III [Escherichia coli].	28.25	570	356	18	7	544	4	552	1e-39	164
rs:WP_001694638	DNA topoisomerase III family protein [Escherichia coli].	28.07	570	357	17	7	544	4	552	1e-39	164
rs:WP_043039283	DNA topoisomerase [Streptococcus equi].	26.09	571	372	14	7	569	5	533	1e-39	162
rs:WP_004318624	DNA topoisomerase I [Bacteroides ovatus].	28.80	500	307	16	72	550	2	473	1e-39	163
rs:WP_007216070	DNA topoisomerase I [Bacteroides cellulosilyticus].	27.53	563	362	18	4	550	1	533	1e-39	163
rs:WP_010742428	DNA topoisomerase III [Enterococcus malodoratus].	29.12	467	289	13	108	556	1	443	1e-39	162
rs:WP_034023840	hypothetical protein [Pseudomonas aeruginosa].	26.36	569	367	14	5	551	3	541	1e-39	164
rs:WP_008777083	DNA topoisomerase I [Bacteroides sp. 2_2_4].	27.83	557	348	19	4	539	1	524	1e-39	163
rs:WP_010345965	DNA topoisomerase III [Paenibacillus peoriae].	25.20	631	399	19	5	599	3	596	1e-39	164
rs:WP_015336640	DNA topoisomerase type IA central domain protein [Desulfovibrio hydrothermalis].	27.14	619	408	17	7	602	4	602	1e-39	164
rs:WP_007545235	DNA topoisomerase III, partial [Listeria fleischmannii].	28.51	435	268	15	170	590	5	410	1e-39	162
rs:WP_044707261	DNA topoisomerase III [Escherichia coli].	27.96	565	363	17	7	544	4	551	1e-39	164
rs:WP_046442595	DNA topoisomerase III [Catabacter hongkongensis].	27.79	565	346	19	7	550	4	527	1e-39	163
rs:WP_016286623	DNA topoisomerase III [Lachnospiraceae bacterium 3-1].	28.11	555	334	19	7	539	4	515	1e-39	163
rs:WP_001505316	DNA topoisomerase III family protein [Escherichia coli].	28.19	557	347	18	7	531	4	539	1e-39	164
rs:WP_002320596	DNA topoisomerase [Enterococcus faecium].	27.77	515	345	14	43	544	20	520	1e-39	163
rs:WP_024733367	DNA topoisomerase III [Clostridiales bacterium VE202-14].	26.56	546	336	18	7	532	5	505	1e-39	163
rs:WP_001675950	DNA topoisomerase III [Salmonella enterica].	28.07	570	357	17	7	544	4	552	1e-39	164
rs:WP_008653364	DNA topoisomerase I [Bacteroides sp. 3_1_33FAA].	25.62	605	401	18	4	591	1	573	1e-39	163
rs:WP_032640105	DNA topoisomerase III [Enterobacter sp. EGD-HP1].	28.12	569	363	18	8	548	5	555	1e-39	164
rs:WP_031622287	DNA topoisomerase III [Salmonella enterica].	28.07	570	357	17	7	544	4	552	1e-39	164
rs:WP_022757070	DNA topoisomerase III [Butyrivibrio fibrisolvens].	27.18	618	376	19	3	553	2	612	1e-39	163
rs:WP_042932890	DNA topoisomerase III, partial [Pseudomonas coronafaciens].	31.60	288	181	6	275	549	5	289	2e-39	160
rs:WP_023198293	DNA topoisomerase III, partial [Salmonella enterica].	33.82	275	171	6	285	552	30	300	2e-39	159
rs:WP_039430831	DNA topoisomerase I [Porphyromonas gulae].	27.29	568	355	19	7	550	4	537	2e-39	163
rs:WP_032532245	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	26.33	566	370	16	4	552	1	536	2e-39	163
rs:WP_044190226	DNA topoisomerase I [Porphyromonas sp. COT-290 OH860].	24.68	632	411	18	4	602	1	600	2e-39	163
rs:WP_034014013	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	31.99	297	181	7	8	298	5	286	2e-39	156
rs:WP_023926441	hypothetical protein [Prevotella nigrescens].	25.00	572	367	17	5	553	3	535	2e-39	163
rs:WP_022250918	DNA topoisomerase III [Clostridium nexile CAG:348].	26.64	608	386	20	5	570	4	593	2e-39	163
rs:WP_029881403	MULTISPECIES: hypothetical protein [Paenibacillus].	28.05	606	375	22	29	603	13	588	2e-39	163
tr:A0A0A8VYF7_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.67	553	347	20	7	543	5	520	2e-39	163
rs:WP_006256385	DNA topoisomerase I [Alloprevotella tannerae].	26.37	565	338	17	5	531	3	527	2e-39	163
rs:WP_036059528	hypothetical protein [Listeria weihenstephanensis].	26.67	570	357	21	7	559	4	529	2e-39	163
rs:WP_036930050	DNA topoisomerase I [Prevotella timonensis].	27.07	543	351	17	4	531	1	513	2e-39	163
rs:WP_032242288	DNA topoisomerase III, partial [Escherichia coli].	28.39	539	336	16	38	544	8	528	2e-39	163
tr:A9KSH4_CLOPH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.70	646	370	22	8	554	13	647	2e-39	163
rs:WP_008141550	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	26.95	564	361	19	4	550	1	530	2e-39	163
rs:WP_007215190	DNA topoisomerase I [Bacteroides cellulosilyticus].	25.49	561	373	13	4	550	1	530	2e-39	163
rs:WP_034490071	DNA topoisomerase III [Butyrivibrio fibrisolvens].	27.18	618	376	19	3	553	2	612	2e-39	163
rs:WP_014281498	DNA topoisomerase III [Paenibacillus terrae].	25.63	632	395	20	5	599	3	596	2e-39	164
rs:WP_005805519	DNA topoisomerase I [Bacteroides fragilis].	26.52	543	336	14	7	531	4	501	2e-39	163
rs:WP_040121204	DNA topoisomerase III [Salmonella enterica].	28.07	570	357	17	7	544	4	552	2e-39	163
rs:WP_036849905	DNA topoisomerase I [Porphyromonas macacae].	26.26	556	338	17	7	531	4	518	2e-39	163
tr:E7PTU5_PSESG	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFW82968.1};	26.83	492	327	10	101	565	2	487	2e-39	162
rs:WP_032707380	DNA topoisomerase III, partial [Pseudomonas savastanoi].	26.83	492	327	10	101	565	2	487	2e-39	162
tr:F2ZR01_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.60	288	181	6	275	549	14	298	2e-39	159
rs:WP_046940204	hypothetical protein, partial [Xanthomonas euvesicatoria].	27.59	424	267	10	161	549	21	439	2e-39	162
rs:WP_009228524	DNA topoisomerase I [Prevotella sp. oral taxon 299].	26.36	569	357	18	5	550	3	532	2e-39	163
rs:WP_025731506	DNA topoisomerase III [Bacillus ginsengihumi].	27.63	579	380	15	4	571	3	553	2e-39	163
rs:WP_008674864	DNA topoisomerase III [Bacteroides sp. 9_1_42FAA].	26.19	569	356	19	7	531	2	550	2e-39	163
rs:WP_023208305	DNA topoisomerase III [Salmonella enterica].	28.60	570	356	19	8	546	5	554	2e-39	163
rs:WP_032812369	DNA topoisomerase I [Bacteroides xylanisolvens].	25.04	611	394	15	4	592	1	569	2e-39	163
rs:WP_002370803	DNA topoisomerase III [Enterococcus faecium].	25.81	620	386	21	7	601	6	576	2e-39	163
rs:WP_004010072	DNA topoisomerase, partial [Escherichia coli].	28.39	539	336	16	38	544	16	536	2e-39	162
rs:WP_007840712	MULTISPECIES: DNA topoisomerase III [Bacteroides].	26.19	569	356	19	7	531	2	550	2e-39	163
rs:WP_032941057	DNA topoisomerase III [Bacteroides sp. 3_1_33FAA].	26.19	569	356	19	7	531	2	550	2e-39	163
tr:W8YT76_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.68	566	356	17	5	539	3	540	2e-39	164
rs:WP_041703756	DNA topoisomerase III [Lachnoclostridium phytofermentans].	25.70	646	370	22	8	554	7	641	2e-39	163
rs:WP_009229667	DNA topoisomerase I [Prevotella sp. oral taxon 317].	26.13	551	347	16	4	531	2	515	2e-39	163
rs:WP_018109310	DNA topoisomerase I [Bacteroides propionicifaciens].	26.50	551	343	17	5	531	3	515	2e-39	163
rs:WP_007856244	DNA topoisomerase III [Bacteroides dorei].	26.19	569	356	19	7	531	2	550	2e-39	163
tr:U7TS60_FUSNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.39	555	355	19	7	550	4	521	2e-39	162
rs:WP_032945967	DNA topoisomerase I [Bacteroides vulgatus].	26.97	571	354	17	7	550	4	538	2e-39	163
rs:WP_038653193	DNA topoisomerase I [Mucinivorans hirudinis].	26.64	608	369	22	4	584	1	558	2e-39	163
rs:WP_032856232	DNA topoisomerase I [Bacteroides ovatus].	28.60	500	308	16	72	550	2	473	2e-39	162
rs:WP_031612378	DNA topoisomerase III, partial [Salmonella enterica].	34.31	341	199	12	8	340	5	328	2e-39	157
rs:WP_008667766	MULTISPECIES: DNA topoisomerase III [Bacteroides].	26.49	570	353	20	7	531	2	550	2e-39	163
rs:WP_012419946	DNA topoisomerase III [Akkermansia muciniphila].	27.27	583	359	21	3	548	2	556	2e-39	164
tr:D4WMC6_BACOV	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.60	500	308	16	72	550	19	490	2e-39	162
rs:WP_021566151	hypothetical protein [Escherichia coli].	28.12	569	360	18	7	546	4	552	2e-39	163
tr:B1BLL7_CLOPF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.52	561	356	17	7	550	5	537	3e-39	162
rs:WP_019910740	DNA topoisomerase III [Paenibacillus sp. HW567].	25.27	641	399	20	5	600	3	608	3e-39	163
rs:WP_029517449	DNA topoisomerase III [Paenibacillus polymyxa].	25.31	640	400	21	5	600	3	608	3e-39	163
rs:WP_033801728	DNA topoisomerase III, partial [Escherichia coli].	28.19	525	332	16	7	507	4	507	3e-39	160
rs:WP_031874330	DNA topoisomerase III, partial [Staphylococcus aureus].	27.20	478	305	15	7	473	5	450	3e-39	160
rs:WP_025682658	DNA topoisomerase III [Paenibacillus sp. 1-49].	25.63	632	395	20	5	599	3	596	3e-39	163
rs:WP_032221747	DNA topoisomerase III, partial [Escherichia coli].	28.39	539	336	16	38	544	8	528	3e-39	162
rs:WP_046434613	DNA topoisomerase III [Akkermansia sp. UNK.MGS-1].	27.27	583	359	21	3	548	2	556	3e-39	164
rs:WP_005922872	DNA topoisomerase III [Faecalibacterium prausnitzii].	25.94	613	380	23	3	590	2	565	3e-39	162
rs:WP_022769064	DNA topoisomerase III [Butyrivibrio sp. NC2007].	26.02	611	386	19	1	553	1	603	3e-39	162
rs:WP_036611732	DNA topoisomerase III [Oribacterium sp. P6A1].	26.90	580	331	21	7	539	4	537	3e-39	162
rs:WP_012457228	DNA topoisomerase I [Porphyromonas gingivalis].	24.53	632	412	18	4	602	1	600	3e-39	162
rs:WP_007653480	DNA topoisomerase I [Parabacteroides goldsteinii].	27.66	564	360	19	4	550	1	533	3e-39	162
tr:W1E140_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.79	341	220	8	220	548	3	339	3e-39	159
rs:WP_008766823	DNA topoisomerase I [Bacteroides sp. 1_1_6].	28.26	545	345	19	4	531	1	516	3e-39	162
rs:WP_010992404	DNA topoisomerase I [Bacteroides fragilis].	28.26	545	345	19	4	531	1	516	3e-39	162
rs:WP_023038729	DNA topoisomerase III [Fusobacterium nucleatum].	26.66	574	356	16	7	548	6	546	3e-39	163
rs:WP_018969030	hypothetical protein [Rubritalea marina].	27.10	583	367	22	3	548	2	563	3e-39	164
rs:WP_044021390	DNA topoisomerase [Streptococcus sp. VT 162].	25.57	567	353	16	4	550	2	519	3e-39	161
rs:WP_021661971	DNA topoisomerase [Porphyromonas gingivalis].	26.21	557	337	18	7	531	4	518	3e-39	162
rs:WP_047090416	DNA topoisomerase III [Escherichia coli].	28.07	570	357	17	7	544	4	552	3e-39	162
rs:WP_025966435	DNA topoisomerase I [Bacillus cereus].	28.10	516	323	13	43	539	46	532	3e-39	164
rs:WP_041516059	DNA topoisomerase I [Flavobacterium hibernum].	27.07	580	345	20	4	550	1	535	3e-39	162
rs:WP_005794081	DNA topoisomerase I [Bacteroides fragilis].	25.91	606	388	20	4	592	1	562	3e-39	162
rs:WP_021979974	DNA topoisomerase III [Paraprevotella clara CAG:116].	28.26	545	345	18	4	531	1	516	3e-39	162
rs:WP_031834544	DNA topoisomerase III, partial [Staphylococcus aureus].	27.20	478	305	15	7	473	5	450	3e-39	159
rs:WP_034491856	DNA topoisomerase III, partial [Butyrivibrio fibrisolvens].	27.35	618	375	20	3	553	2	612	3e-39	162
tr:A0A014MIW0_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.11	568	340	22	28	550	17	555	3e-39	164
rs:WP_004319756	DNA topoisomerase I [Bacteroides ovatus].	27.53	563	362	18	4	550	1	533	3e-39	162
rs:WP_003482634	DNA topoisomerase III [Clostridium perfringens].	28.52	561	356	17	7	550	5	537	3e-39	162
tr:D1K925_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEZ19663.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EEZ19663.1};	26.19	569	356	19	7	531	13	561	3e-39	162
rs:WP_009347193	DNA topoisomerase I [Alloprevotella rava].	24.80	633	409	19	4	602	1	600	3e-39	162
rs:WP_032893455	DNA topoisomerase [Fusobacterium nucleatum].	27.39	555	355	19	7	550	8	525	3e-39	162
rs:WP_004335184	DNA topoisomerase I [Porphyromonas endodontalis].	26.09	552	344	15	5	531	3	515	4e-39	162
rs:WP_029503437	DNA topoisomerase III [Lachnoclostridium phytofermentans].	25.93	648	366	23	8	554	7	641	4e-39	162
rs:WP_018964968	DNA topoisomerase I [Porphyromonas gulae].	25.95	551	343	15	7	531	5	516	4e-39	162
rs:WP_014194428	DNA topoisomerase [Burkholderia sp. YI23].	27.69	603	374	20	7	567	6	588	4e-39	164
rs:WP_035230495	DNA topoisomerase III [Desulfobulbus sp. Tol-SR].	26.94	579	369	24	1	550	1	554	4e-39	163
rs:WP_017707254	DNA topoisomerase III, partial [Pseudomonas syringae].	30.15	335	216	7	230	549	5	336	4e-39	159
tr:F3HNM9_PSEYM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.38	281	174	6	282	549	1	278	4e-39	158
rs:WP_014112244	DNA topoisomerase III [Oscillibacter valericigenes].	25.95	659	405	24	8	607	5	639	4e-39	162
rs:WP_007483903	DNA topoisomerase I [Bacteroides nordii].	27.84	564	359	20	4	550	1	533	4e-39	162
rs:WP_044164756	DNA topoisomerase III [Bacteroides reticulotermitis].	26.35	573	346	19	7	531	2	546	4e-39	162
rs:WP_041531187	hypothetical protein, partial [Persephonella marina].	26.30	559	314	21	7	531	4	498	4e-39	161
rs:WP_021894879	DNA topoisomerase [Clostridium bolteae CAG:59].	25.75	602	359	23	8	532	7	597	4e-39	162
rs:WP_009347068	DNA topoisomerase I [Alloprevotella rava].	26.18	550	346	17	5	531	3	515	4e-39	162
rs:WP_039956461	DNA topoisomerase III [Bacillus sp. M 2-6].	28.38	606	388	23	7	602	6	575	4e-39	162
rs:WP_001235765	DNA topoisomerase III [Escherichia coli].	28.19	557	347	18	7	531	4	539	5e-39	162
rs:WP_033949820	DNA topoisomerase III [Pseudomonas aeruginosa].	25.74	606	394	15	8	573	5	594	5e-39	162
rs:WP_028590812	DNA topoisomerase III [Paenibacillus panacisoli].	25.87	630	398	20	5	599	3	598	5e-39	162
rs:WP_025147939	DNA topoisomerase I [Bacillus sp. H1a].	27.48	564	355	14	5	544	4	537	5e-39	163
tr:A0A011RAP0_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.66	593	342	22	7	550	6	560	5e-39	163
rs:WP_004068688	DNA topoisomerase III [Clostridium sp. ASF502].	25.67	600	378	21	8	550	7	595	5e-39	162
rs:WP_015499506	DNA recombination protein RmuC [Octadecabacter antarcticus].	26.53	554	342	16	7	531	6	523	5e-39	162
rs:WP_011876105	DNA topoisomerase [Burkholderia vietnamiensis].	26.99	604	381	18	5	567	4	588	5e-39	163
tr:A0A017NAF6_BACFG	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EYE44609.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EYE44609.1};	26.47	529	323	17	43	531	26	528	5e-39	162
rs:WP_046532154	DNA topoisomerase III, partial [Candidatus Accumulibacter phosphatis].	27.85	578	360	19	7	550	6	560	5e-39	163
rs:WP_026503225	DNA topoisomerase III [Bifidobacterium boum].	26.69	592	341	23	7	548	4	552	5e-39	162
rs:WP_042562302	hypothetical protein [Yersinia frederiksenii].	27.75	573	361	18	8	543	6	562	5e-39	162
rs:WP_009004429	DNA topoisomerase III [Clostridium sp. D5].	26.39	576	355	19	2	550	3	536	5e-39	162
rs:WP_001832808	MULTISPECIES: DNA topoisomerase [Staphylococcus].	28.06	588	334	23	5	544	3	549	5e-39	162
tr:I4V807_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.38	606	388	23	7	602	4	573	5e-39	161
rs:WP_046337887	DNA topoisomerase III, partial [Xenorhabdus bovienii].	37.22	266	154	7	308	563	1	263	5e-39	157
rs:WP_005650116	DNA topoisomerase I [Parabacteroides merdae].	28.35	575	351	22	4	550	1	542	5e-39	162
rs:WP_012806869	DNA topoisomerase III [Candidatus Accumulibacter phosphatis].	27.73	577	362	20	7	550	6	560	5e-39	163
rs:WP_016084166	DNA topoisomerase III [Bacillus cereus].	27.24	558	364	15	5	544	4	537	5e-39	163
rs:WP_017895115	hypothetical protein [Clostridium tyrobutyricum].	29.00	562	339	20	7	543	4	530	5e-39	162
rs:WP_022140739	DNA topoisomerase III [Clostridium sp. CAG:230].	26.48	608	351	22	7	532	6	599	5e-39	162
rs:WP_034064609	DNA topoisomerase III [Pseudomonas aeruginosa].	25.74	606	394	15	8	573	5	594	5e-39	162
rs:WP_027374792	DNA topoisomerase I [Chryseobacterium sp. UNC8MFCol].	26.54	569	366	19	4	552	1	537	5e-39	162
rs:WP_027147611	DNA topoisomerase [Methylobacter tundripaludum].	27.85	571	336	19	4	531	1	538	5e-39	162
rs:WP_021956947	DNA topoisomerase [Eubacterium sp. CAG:115].	26.08	579	358	15	7	556	4	541	6e-39	161
rs:WP_019423903	DNA topoisomerase III [Paenibacillus sp. OSY-SE].	25.66	643	394	21	5	599	3	609	6e-39	162
rs:WP_016526652	DNA topoisomerase [Lactobacillus plantarum].	29.26	581	375	16	5	566	3	566	6e-39	162
rs:WP_025072617	DNA topoisomerase I [Prevotella timonensis].	26.73	550	339	18	7	531	5	515	6e-39	161
rs:WP_023056934	DNA topoisomerase [Prevotella sp. BV3P1].	26.07	606	387	20	4	592	1	562	6e-39	161
rs:WP_039652910	hypothetical protein [Clostridium tyrobutyricum].	29.17	552	331	20	7	533	4	520	6e-39	162
rs:WP_008707174	DNA topoisomerase III [Rhodopirellula maiorica].	28.02	571	356	18	4	553	1	537	6e-39	162
rs:WP_039657745	hypothetical protein [Clostridium tyrobutyricum].	28.83	562	340	20	7	543	4	530	6e-39	162
rs:WP_002604273	DNA topoisomerase III [[Clostridium] hathewayi].	25.47	589	365	19	8	532	7	585	6e-39	161
rs:WP_026667054	MULTISPECIES: DNA topoisomerase III [Butyrivibrio].	25.35	572	369	14	7	561	6	536	6e-39	161
rs:WP_025531786	DNA topoisomerase III [[Clostridium] hathewayi].	25.81	589	363	20	8	532	7	585	6e-39	161
rs:WP_025722650	DNA topoisomerase III [Paenibacillus polymyxa].	25.20	631	399	20	5	599	3	596	6e-39	162
rs:WP_046232591	DNA topoisomerase III [Paenibacillus algorifonticola].	26.86	618	390	19	7	590	5	594	6e-39	162
rs:WP_025078801	DNA topoisomerase I [Prevotella fusca].	25.70	572	357	18	5	550	3	532	6e-39	161
rs:WP_029471610	DNA topoisomerase III [Clostridiales bacterium VE202-06].	25.85	588	365	21	7	566	4	548	6e-39	161
rs:WP_036929574	DNA topoisomerase I, partial [Prevotella timonensis].	26.41	549	346	16	5	531	3	515	6e-39	161
tr:A0A078RJZ0_BACVU	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:KDS34242.1};	26.83	574	357	17	4	550	3	540	7e-39	161
rs:WP_022418595	DNA topoisomerase [Acidiphilium sp. CAG:727].	28.77	570	342	21	4	544	1	535	7e-39	161
rs:WP_036846849	MULTISPECIES: DNA topoisomerase I [Porphyromonas].	25.77	555	345	16	4	531	2	516	7e-39	161
rs:WP_003509283	DNA topoisomerase III [[Clostridium] symbiosum].	27.02	570	351	20	3	550	2	528	7e-39	161
rs:WP_004353783	DNA topoisomerase I [Prevotella denticola].	25.95	551	348	17	4	531	2	515	7e-39	161
tr:R3T638_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.34	484	305	15	5	468	4	470	7e-39	159
rs:WP_007656370	DNA topoisomerase I [Parabacteroides goldsteinii].	26.09	598	381	20	4	584	1	554	7e-39	161
rs:WP_013815808	DNA topoisomerase I [Porphyromonas gingivalis].	24.49	633	411	19	4	602	1	600	7e-39	161
rs:WP_025434990	DNA topoisomerase III [Eubacterium acidaminophilum].	29.04	551	329	19	7	539	4	510	7e-39	161
rs:WP_037608064	DNA topoisomerase [Streptococcus sp. CM7].	26.11	609	394	19	7	603	5	569	7e-39	160
rs:WP_044907008	DNA topoisomerase III [[Clostridium] innocuum].	26.08	556	357	18	5	531	3	533	7e-39	162
tr:X8JXS9_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.11	609	394	19	7	603	9	573	7e-39	160
rs:WP_005539987	DNA topoisomerase III [Johnsonella ignava].	29.86	432	272	12	8	417	6	428	7e-39	161
rs:WP_037526447	DNA topoisomerase I, partial [Sphingobacterium sp. IITKGP-BTPF85].	28.57	462	282	14	7	450	4	435	7e-39	158
rs:WP_004083178	DNA topoisomerase III [Clostridium sp. ASF502].	25.30	585	373	17	7	566	4	549	7e-39	161
rs:WP_014298777	DNA topoisomerase I [Bacteroides fragilis].	27.11	557	352	18	4	539	1	524	7e-39	161
rs:WP_022020959	DNA topoisomerase [Bacteroides sp. CAG:661].	28.35	575	351	22	4	550	1	542	7e-39	161
rs:WP_039271318	DNA topoisomerase III [Paenibacillus polymyxa].	25.16	640	401	21	5	600	3	608	8e-39	162
rs:WP_029902380	DNA topoisomerase I [Prevotella sp. 10(H)].	24.36	628	393	18	4	590	1	587	8e-39	161
rs:WP_034486619	DNA topoisomerase III [Butyrivibrio fibrisolvens].	26.69	622	374	19	3	553	2	612	8e-39	161
rs:WP_022423482	DNA topoisomerase [Clostridium sp. CAG:440].	27.80	464	297	13	7	441	6	460	8e-39	159
rs:WP_013265186	DNA topoisomerase I [Prevotella melaninogenica].	25.54	552	349	16	5	531	3	517	8e-39	161
rs:WP_038605690	DNA topoisomerase III [Bacteroides dorei].	25.88	568	359	18	7	531	2	550	8e-39	161
rs:WP_035038491	DNA topoisomerase III [Aquabacterium sp. NJ1].	27.29	612	374	22	7	567	6	597	8e-39	162
tr:R2RVG6_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.11	505	328	17	7	495	5	495	8e-39	159
rs:WP_046676093	DNA topoisomerase I [Sphingobacterium sp. Ag1].	26.36	569	367	17	4	552	1	537	8e-39	161
rs:WP_006740590	DNA topoisomerase III [Streptococcus urinalis].	26.11	609	394	19	7	604	4	567	8e-39	160
tr:W7ZEP5_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.79	535	359	15	38	555	23	536	8e-39	161
rs:WP_008778183	DNA topoisomerase I [Parabacteroides sp. 20_3].	25.04	611	394	15	4	592	1	569	8e-39	161
rs:WP_036868224	DNA topoisomerase I [Porphyromonas canoris].	24.96	633	408	19	4	602	1	600	8e-39	161
rs:WP_001235766	DNA topoisomerase III [Escherichia albertii].	27.26	565	367	16	7	544	4	551	8e-39	161
rs:WP_012345266	DNA topoisomerase III [Leptothrix cholodnii].	27.04	577	354	22	3	531	2	559	8e-39	162
rs:WP_002592974	DNA topoisomerase III [[Clostridium] clostridioforme].	26.43	560	358	16	7	550	4	525	9e-39	161
rs:WP_045673653	DNA topoisomerase III [Paenibacillus beijingensis].	26.60	564	358	17	5	540	3	538	9e-39	162
rs:WP_001547190	DNA topoisomerase III [Escherichia coli].	28.10	573	355	19	7	546	4	552	9e-39	161
rs:WP_027116342	DNA topoisomerase III [Lachnospiraceae bacterium P6B14].	24.55	672	374	22	7	554	6	668	9e-39	161
rs:WP_032596729	DNA topoisomerase I [Bacteroides fragilis].	25.67	561	372	13	4	550	1	530	9e-39	161
tr:F3QUZ7_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EGG53247.1};	25.95	555	362	15	4	539	2	526	9e-39	161
rs:WP_005643615	DNA topoisomerase I [Parabacteroides merdae].	27.16	556	353	16	4	539	1	524	9e-39	161
rs:WP_004364080	DNA topoisomerase III [Prevotella nigrescens].	25.28	621	399	19	4	591	1	589	9e-39	161
rs:WP_042994218	DNA topoisomerase I [Bacteroides fragilis].	27.84	564	359	20	4	550	1	533	9e-39	161
tr:T4J8S2_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.00	525	309	22	56	563	2	474	9e-39	160
rs:WP_035016504	DNA topoisomerase, partial [Enterococcus raffinosus].	29.11	505	328	17	7	495	5	495	9e-39	159
rs:WP_006060481	DNA topoisomerase III [Holdemania filiformis].	26.18	638	386	26	3	607	2	587	1e-38	161
rs:WP_002193616	DNA topoisomerase I [Bacillus cereus].	27.26	521	331	13	43	544	46	537	1e-38	162
rs:WP_005800238	DNA topoisomerase I [Bacteroides fragilis].	27.11	557	352	18	4	539	1	524	1e-38	161
tr:M1P191_DESSD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.87	530	342	16	35	553	16	521	1e-38	160
rs:WP_027996519	DNA topoisomerase III [Simplicispira psychrophila].	28.10	580	345	22	5	536	4	559	1e-38	163
rs:WP_041193069	DNA topoisomerase III, partial [Candidatus Profftella armatura].	28.72	571	341	19	7	540	6	547	1e-38	162
rs:WP_013407034	DNA topoisomerase [Leadbetterella byssophila].	26.40	572	359	16	4	550	1	535	1e-38	160
rs:WP_018709306	DNA topoisomerase I [Bacteroides barnesiae].	28.35	575	351	22	4	550	1	542	1e-38	161
rs:WP_032567528	DNA topoisomerase I [Bacteroides fragilis].	26.92	613	380	21	4	592	1	569	1e-38	160
rs:WP_032572846	DNA topoisomerase I [Bacteroides fragilis].	25.67	561	372	13	4	550	1	530	1e-38	160
rs:WP_040647948	hypothetical protein [Ruminococcus callidus].	25.54	556	356	16	7	539	4	524	1e-38	160
rs:WP_016172934	DNA topoisomerase III [Enterococcus dispar].	28.34	561	328	19	7	550	6	509	1e-38	160
rs:WP_044648482	DNA topoisomerase III [Paenibacillus terrae].	25.63	632	395	20	5	599	3	596	1e-38	162
rs:WP_044300564	DNA topoisomerase I [Bacteroides fragilis].	28.01	564	358	20	4	550	1	533	1e-38	160
tr:S5R840_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.72	571	341	19	7	540	6	547	1e-38	162
rs:WP_023650177	DNA topoisomerase III family protein, partial [Vibrio parahaemolyticus].	34.30	277	172	5	279	548	19	292	1e-38	157
rs:WP_016220887	DNA topoisomerase III [Dorea sp. 5-2].	26.80	582	361	17	7	563	4	545	1e-38	160
rs:WP_015267011	topoisomerase IA [Echinicola vietnamensis].	27.36	552	344	17	4	531	1	519	1e-38	160
tr:B5D0F1_BACPM	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EDY94995.1};	27.43	576	336	20	5	531	31	573	1e-38	161
rs:WP_031890592	DNA topoisomerase III, partial [Staphylococcus aureus].	30.94	446	283	12	107	544	11	439	1e-38	159
rs:WP_032530912	DNA topoisomerase I [Bacteroides fragilis].	27.34	556	352	18	4	539	1	524	1e-38	160
rs:WP_001727078	DNA topoisomerase III, partial [Salmonella enterica].	33.58	271	169	6	289	552	2	268	1e-38	156
rs:WP_032135135	DNA topoisomerase I [Alistipes sp. AL-1].	27.11	546	346	17	7	531	4	518	1e-38	160
rs:WP_007485367	MULTISPECIES: DNA topoisomerase I [Bacteroides].	27.29	557	351	18	4	539	1	524	1e-38	160
rs:WP_044135992	DNA topoisomerase I [Bacteroides fragilis].	28.01	564	358	20	4	550	1	533	1e-38	160
rs:WP_017752917	hypothetical protein [Clostridium tyrobutyricum].	29.00	562	339	20	7	543	4	530	1e-38	161
gp:CP003859_761	DNA topoisomerase III [Streptococcus constellatus subsp. pharyngis C1050]	26.11	609	394	19	7	603	9	573	1e-38	159
rs:WP_021825728	DNA topoisomerase III [Prevotella salivae].	25.82	550	348	15	5	531	3	515	1e-38	160
rs:WP_043032798	hypothetical protein [Clostridium botulinum].	27.69	549	341	21	7	533	5	519	1e-38	161
tr:F7SZR1_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.92	548	339	18	34	550	10	532	1e-38	162
rs:WP_045497641	DNA topoisomerase I [Chryseobacterium sp. StRB126].	27.81	579	342	20	4	550	1	535	1e-38	160
rs:WP_028897449	DNA topoisomerase I [Prevotella sp. HUN102].	25.12	633	407	19	4	602	1	600	1e-38	160
rs:WP_021663186	DNA topoisomerase, partial [Porphyromonas gingivalis].	24.49	633	411	19	4	602	1	600	1e-38	160
tr:R2AW14_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.34	484	305	15	5	468	4	470	1e-38	158
rs:WP_032846518	MULTISPECIES: DNA topoisomerase I [Bacteroides].	27.34	556	352	18	4	539	1	524	1e-38	160
rs:WP_001722392	DNA topoisomerase III family protein [Escherichia coli].	27.89	570	358	17	7	544	4	552	1e-38	160
tr:K5Y4M0_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKN08087.1};	26.15	566	371	16	4	552	2	537	1e-38	160
rs:WP_032948782	DNA topoisomerase I [Bacteroides vulgatus].	26.80	571	355	17	7	550	4	538	1e-38	160
tr:D4V835_BACVU	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFG17986.1};	26.15	566	371	16	4	552	2	537	1e-38	160
rs:WP_009000847	DNA topoisomerase I [Bacteroides sp. D2].	27.48	564	361	19	4	550	1	533	1e-38	160
rs:WP_034893651	DNA topoisomerase III, partial [Candidatus Accumulibacter sp. SK-11].	27.44	583	356	19	7	550	6	560	1e-38	160
rs:WP_022032138	DNA topoisomerase III [Clostridium hathewayi CAG:224].	26.15	589	361	22	8	532	7	585	1e-38	160
rs:WP_041787144	DNA topoisomerase [Streptococcus constellatus].	26.11	609	394	19	7	603	5	569	1e-38	159
rs:WP_028541705	DNA topoisomerase III [Paenibacillus sp. UNCCL52].	25.36	631	398	20	5	599	3	596	1e-38	161
rs:WP_042007418	hypothetical protein [Capnocytophaga canimorsus].	26.98	619	383	20	5	590	3	585	1e-38	160
rs:WP_022041252	DNA topoisomerase III [Bacteroides sp. CAG:702].	27.18	563	349	17	7	531	2	541	1e-38	160
rs:WP_021315120	DNA topoisomerase III [Dehalobacter sp. UNSWDHB].	27.55	548	341	18	7	539	4	510	2e-38	160
tr:J1BJU3_STREE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.21	557	354	19	56	601	4	514	2e-38	159
rs:WP_032600052	DNA topoisomerase I [Bacteroides fragilis].	27.29	557	351	18	4	539	1	524	2e-38	160
rs:WP_002502793	DNA topoisomerase [Staphylococcus epidermidis].	27.77	587	337	22	5	544	3	549	2e-38	160
rs:WP_006882087	MULTISPECIES: topoisomerase [Enterobacteriaceae].	25.45	617	383	17	8	572	5	596	2e-38	160
rs:WP_022937740	DNA topoisomerase III [Dielma fastidiosa].	25.54	560	366	13	5	539	3	536	2e-38	160
tr:J6CXX6_PASMD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.20	511	324	17	8	485	5	500	2e-38	158
rs:WP_009012816	DNA topoisomerase I [Prevotella sp. C561].	27.17	552	338	17	5	531	3	515	2e-38	160
rs:WP_000520744	DNA topoisomerase I [Bacillus cereus].	26.58	568	367	14	43	590	46	583	2e-38	162
rs:WP_026520344	DNA topoisomerase III [Butyrivibrio sp. FCS006].	25.86	611	387	19	1	553	1	603	2e-38	160
rs:WP_044546247	DNA topoisomerase I, partial [Parabacteroides distasonis].	25.56	579	366	17	4	550	1	546	2e-38	159
rs:WP_026522671	DNA topoisomerase III [Butyrivibrio sp. VCB2001].	25.86	611	387	19	1	553	1	603	2e-38	160
rs:WP_006775974	DNA topoisomerase III [[Clostridium] hathewayi].	26.15	589	361	21	8	532	7	585	2e-38	160
rs:WP_031236772	DNA topoisomerase III, partial [Salmonella enterica].	25.58	563	368	16	48	574	1	548	2e-38	159
rs:WP_029199505	DNA topoisomerase III [Oribacterium sp. NK2B42].	24.83	572	372	14	7	561	6	536	2e-38	160
tr:M1JAI4_PHODP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.89	502	327	14	7	491	4	487	2e-38	158
rs:WP_029505782	DNA topoisomerase III [Lachnospiraceae bacterium AC2012].	26.21	622	370	24	8	554	7	614	2e-38	160
rs:WP_031935420	DNA topoisomerase III, partial [Escherichia coli].	29.72	360	234	10	43	391	7	358	2e-38	155
rs:WP_009064311	DNA topoisomerase III [Clostridium sp. MSTE9].	26.24	583	360	18	7	563	4	542	2e-38	160
rs:WP_017648013	DNA topoisomerase [Streptococcus agalactiae].	26.29	563	362	18	7	557	5	526	2e-38	159
rs:WP_028509289	hypothetical protein [Ruminococcus sp. NK3A76].	28.16	554	327	19	7	540	4	506	2e-38	160
rs:WP_018783115	DNA topoisomerase I [Bacillus sp. 95MFCvi2.1].	26.98	582	348	15	5	547	4	547	2e-38	162
rs:WP_012961408	DNA topoisomerase III [Streptococcus gallolyticus].	25.81	616	400	20	7	607	9	582	2e-38	159
tr:K9E6L5_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKU91481.1};	26.87	547	350	18	4	531	2	517	2e-38	160
rs:WP_011108225	DNA topoisomerase III [Bacteroides thetaiotaomicron].	27.29	557	351	18	4	539	1	524	2e-38	160
rs:WP_004612752	hypothetical protein [Tyzzerella nexilis].	25.57	567	356	21	7	550	6	529	2e-38	160
rs:WP_031893288	DNA topoisomerase [Staphylococcus aureus].	27.89	588	335	23	5	544	3	549	2e-38	160
rs:WP_039086265	conjugal transfer protein TraE, partial [Gallibacterium anatis].	29.40	432	282	10	7	428	4	422	2e-38	157
rs:WP_044932415	DNA topoisomerase III [Faecalitalea cylindroides].	25.81	589	364	21	7	566	4	548	2e-38	160
rs:WP_032581436	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	25.77	555	363	15	4	539	1	525	2e-38	160
rs:WP_005947007	DNA topoisomerase III [Blautia hydrogenotrophica].	26.71	569	354	19	3	550	2	528	2e-38	160
tr:W6LQR6_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	24.64	625	377	18	6	557	4	607	2e-38	162
rs:WP_016103582	DNA topoisomerase III [Bacillus cereus].	27.71	516	325	13	43	539	46	532	2e-38	161
rs:WP_031557102	DNA topoisomerase III [Lachnospiraceae bacterium FD2005].	25.88	622	372	23	8	554	7	614	2e-38	160
tr:R6P0H2_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.37	607	357	20	8	532	7	599	2e-38	160
rs:WP_033981023	DNA topoisomerase III [Pseudomonas aeruginosa].	25.66	608	394	15	8	573	5	596	2e-38	160
rs:WP_036651035	DNA topoisomerase I [Parabacteroides distasonis].	26.96	560	349	19	4	539	1	524	2e-38	160
rs:WP_016362159	DNA topoisomerase III [Bacillus cereus].	27.60	558	352	15	5	539	4	532	2e-38	161
rs:WP_035649896	DNA topoisomerase I [Flavobacterium sp. Fl].	27.37	570	356	19	4	550	1	535	2e-38	160
rs:WP_045756432	DNA topoisomerase I [Sphingobacterium sp. PM2-P1-29].	26.73	565	347	19	4	539	1	527	2e-38	160
rs:WP_040313084	DNA topoisomerase III [Bacteroides plebeius].	27.35	574	335	20	7	531	2	542	2e-38	160
rs:WP_025692485	hypothetical protein, partial [Paenibacillus zanthoxyli].	28.04	428	270	12	7	424	5	404	2e-38	156
rs:WP_018884314	DNA topoisomerase III [Paenibacillus massiliensis].	25.87	630	398	20	5	599	3	598	2e-38	160
rs:WP_024549111	MULTISPECIES: DNA topoisomerase III [Cronobacter].	25.45	617	383	17	8	572	5	596	2e-38	160
rs:WP_034431315	ATP-dependent DNA helicase RecQ, partial [Candidatus Contendobacter odensis].	24.64	625	377	18	6	557	2	605	2e-38	162
rs:WP_004574786	DNA topoisomerase [Pseudomonas putida].	27.11	616	374	24	5	581	4	583	3e-38	161
rs:WP_000520726	DNA topoisomerase I [Bacillus cereus].	27.06	558	355	13	5	539	4	532	3e-38	161
rs:WP_005800863	DNA topoisomerase I [Bacteroides fragilis].	27.71	545	348	18	4	531	1	516	3e-38	159
rs:WP_025677653	DNA topoisomerase III [Paenibacillus massiliensis].	25.87	630	398	20	5	599	3	598	3e-38	160
rs:WP_000520753	hypothetical protein, partial [Bacillus cereus].	27.66	517	326	12	42	539	45	532	3e-38	158
rs:WP_009324599	DNA topoisomerase III [Subdoligranulum sp. 4_3_54A2FAA].	26.44	571	353	19	3	550	2	528	3e-38	159
rs:WP_018968363	DNA topoisomerase I [Prevotella loescheii].	25.83	569	360	16	5	550	3	532	3e-38	159
rs:WP_027433226	DNA topoisomerase III [Lachnospiraceae bacterium MD2004].	25.88	622	372	23	8	554	7	614	3e-38	160
rs:WP_015498061	DNA recombination protein RmuC [Octadecabacter antarcticus].	27.26	554	338	19	7	531	6	523	3e-38	160
rs:WP_034898779	DNA topoisomerase III [Erwinia typographi].	25.22	567	370	14	43	567	36	590	3e-38	160
rs:WP_036845243	DNA topoisomerase I, partial [Porphyromonas sp. COT-108 OH1349].	24.73	647	403	19	4	591	1	622	3e-38	159
rs:WP_014298129	DNA topoisomerase I [Bacteroides fragilis].	25.08	634	406	20	4	602	1	600	3e-38	159
rs:WP_034587670	DNA topoisomerase III [Helicobacter magdeburgensis].	25.38	587	383	17	7	562	4	566	3e-38	160
rs:WP_024167399	DNA topoisomerase III, partial [Escherichia coli].	28.20	539	337	16	38	544	1	521	3e-38	159
rs:WP_032938611	DNA topoisomerase I [Bacteroides vulgatus].	26.10	567	370	17	4	552	1	536	3e-38	159
rs:WP_036889583	DNA topoisomerase I [Porphyromonas crevioricanis].	25.76	625	391	22	4	591	1	589	3e-38	159
rs:WP_040110015	hypothetical protein, partial [Thalassospira xiamenensis].	26.40	625	360	22	1	563	1	587	3e-38	159
rs:WP_044942700	DNA topoisomerase III [Blautia schinkii].	25.81	616	381	22	3	590	2	569	3e-38	159
rs:WP_047081943	DNA topoisomerase III [Escherichia coli].	27.70	574	369	18	7	553	4	558	3e-38	159
rs:WP_034525879	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	26.10	567	370	17	4	552	1	536	3e-38	159
rs:WP_000520752	DNA topoisomerase I [Bacillus thuringiensis].	28.10	516	323	13	43	539	46	532	3e-38	161
rs:WP_041783995	DNA topoisomerase [Streptococcus anginosus].	26.62	556	353	15	7	550	5	517	4e-38	158
tr:D5Q4K0_PEPDI	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFH07133.1};	24.80	633	400	21	1	607	1	583	4e-38	159
tr:V1UW93_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	31.70	347	220	7	8	347	5	341	4e-38	154
rs:WP_031504379	DNA topoisomerase I [Chryseobacterium haifense].	27.67	553	340	19	4	531	1	518	4e-38	159
rs:WP_037499141	DNA topoisomerase I [Sphingobacterium sp. ACCC 05744].	27.55	559	343	16	4	531	1	528	4e-38	159
rs:WP_016268745	DNA topoisomerase III [Bacteroides thetaiotaomicron].	27.76	544	349	17	4	531	1	516	4e-38	159
rs:WP_007845849	DNA topoisomerase III [Bacteroides dorei].	26.01	569	357	19	7	531	2	550	4e-38	159
rs:WP_004384681	DNA topoisomerase I [Prevotella veroralis].	25.86	553	344	17	5	531	3	515	4e-38	159
rs:WP_044180300	DNA topoisomerase III, partial [Photobacterium damselae].	27.91	498	324	14	7	487	4	483	4e-38	157
rs:WP_025478727	DNA topoisomerase, partial [Enterococcus faecium].	29.34	467	299	14	5	457	3	452	4e-38	156
rs:WP_046481675	DNA topoisomerase, partial [Pseudomonas veronii].	25.78	609	397	17	5	581	4	589	4e-38	160
tr:F9PXW2_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.54	556	353	16	4	543	2	512	4e-38	157
rs:WP_002151036	DNA topoisomerase I [Bacillus cereus].	27.06	558	355	13	5	539	4	532	4e-38	160
rs:WP_031811082	DNA topoisomerase III, partial [Staphylococcus aureus].	30.94	446	283	12	107	544	11	439	4e-38	158
tr:A0A090P8Q4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.80	273	168	7	283	548	5	274	4e-38	154
rs:WP_033713469	DNA topoisomerase III, partial [Bacillus cereus].	32.02	356	208	13	213	548	8	349	5e-38	157
rs:WP_034735059	DNA topoisomerase I [Chryseobacterium indologenes].	26.70	558	339	17	4	531	1	518	5e-38	159
rs:WP_005338472	hypothetical protein [Dorea formicigenerans].	25.93	567	354	21	7	550	6	529	5e-38	159
rs:WP_011107114	DNA topoisomerase I [Bacteroides thetaiotaomicron].	27.39	566	359	19	4	550	1	533	5e-38	159
tr:G5S0U4_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	37.10	248	141	7	312	549	4	246	5e-38	154
rs:WP_042165951	DNA topoisomerase III [Pseudomonas aeruginosa].	25.58	606	395	15	8	573	5	594	5e-38	159
rs:WP_028898264	DNA topoisomerase III [Prevotella sp. HUN102].	25.70	572	352	17	8	531	5	551	5e-38	158
rs:WP_009296552	DNA topoisomerase III [Clostridium sp. 7_3_54FAA].	27.45	572	346	21	3	550	2	528	5e-38	159
rs:WP_024858731	DNA topoisomerase III [Ruminococcus albus].	26.92	561	348	19	7	552	5	518	5e-38	159
rs:WP_003679507	DNA topoisomerase III [Lactobacillus coryniformis].	25.97	566	359	17	5	563	3	515	5e-38	159
rs:WP_031649805	DNA topoisomerase III, partial [Listeria innocua].	31.37	408	238	14	217	606	1	384	5e-38	157
tr:A0A0C5PL74_SHIFL	SubName: Full=Strain 072 plasmid pSF07202, complete sequence {ECO:0000313|EMBL:AJQ17353.1};	28.11	530	331	16	47	544	5	516	5e-38	159
rs:WP_013310504	DNA topoisomerase III [Paenibacillus polymyxa].	25.52	631	397	20	5	599	3	596	5e-38	160
rs:WP_008616570	DNA topoisomerase I [Paraprevotella clara].	24.88	611	395	15	4	592	1	569	5e-38	159
rs:WP_044137846	DNA topoisomerase I [Bacteroides oleiciplenus].	26.69	547	351	18	4	531	1	516	5e-38	159
tr:J8I0M2_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.02	356	208	12	213	548	27	368	5e-38	157
rs:WP_021769906	DNA topoisomerase III [Leptotrichia sp. oral taxon 225].	27.60	558	351	20	7	548	5	525	5e-38	159
rs:WP_015254593	DNA topoisomerase III [Thermobacillus composti].	24.92	634	400	20	5	599	3	599	5e-38	159
rs:WP_033995596	DNA topoisomerase III [Pseudomonas aeruginosa].	25.49	608	395	15	8	573	5	596	5e-38	159
rs:WP_014546985	DNA topoisomerase [Fibrobacter succinogenes].	27.16	567	332	16	38	544	37	582	5e-38	160
rs:WP_042968464	DNA topoisomerase III [Escherichia coli].	27.69	567	365	17	7	546	4	552	6e-38	159
rs:WP_044727381	DNA topoisomerase III [Pseudomonas aeruginosa].	25.49	608	395	15	8	573	5	596	6e-38	159
rs:WP_016186698	DNA topoisomerase III, partial [Staphylococcus aureus].	28.28	435	269	15	7	430	5	407	6e-38	155
rs:WP_009296637	DNA topoisomerase III [Clostridium sp. 7_3_54FAA].	26.54	569	355	19	3	550	2	528	6e-38	159
rs:WP_033715361	DNA topoisomerase III, partial [Bacillus cereus].	32.02	356	208	12	213	548	17	358	6e-38	157
rs:WP_028545467	DNA topoisomerase III [Paenibacillus taiwanensis].	25.43	637	394	20	7	594	11	615	6e-38	159
rs:WP_042958334	DNA topoisomerase, partial [Enterococcus faecium].	29.28	461	260	15	110	551	1	414	6e-38	155
rs:WP_005423585	DNA topoisomerase III [[Ruminococcus] obeum].	25.81	589	364	21	7	566	4	548	6e-38	159
rs:WP_012263710	DNA topoisomerase [Bacillus thuringiensis].	27.49	553	359	15	5	539	4	532	6e-38	160
rs:WP_016105662	DNA topoisomerase III [Bacillus cereus].	26.88	558	356	14	5	539	4	532	6e-38	160
rs:WP_020367711	hypothetical protein, partial [Staphylococcus epidermidis].	29.78	450	288	13	147	583	2	436	6e-38	156
rs:WP_043037304	DNA topoisomerase [Streptococcus equi].	25.65	620	396	21	7	607	5	578	6e-38	157
tr:R8H0D5_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.02	356	208	12	213	548	31	372	6e-38	157
rs:WP_044563142	DNA topoisomerase [Streptococcus macedonicus].	25.73	618	398	20	7	607	16	589	7e-38	157
rs:WP_021744852	DNA topoisomerase III [Leptotrichia sp. oral taxon 879].	28.26	559	346	20	7	548	5	525	7e-38	158
rs:WP_008816880	MULTISPECIES: DNA topoisomerase III [Clostridiales].	26.31	555	357	17	5	531	3	533	7e-38	159
rs:WP_035314400	DNA topoisomerase III [Clostridium sp. D5].	25.46	597	364	20	5	534	4	586	7e-38	158
rs:WP_045900057	DNA topoisomerase, partial [Enterobacter cloacae].	31.07	354	218	9	198	530	15	363	7e-38	154
tr:C3HV26_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.77	362	201	13	213	548	1	342	7e-38	157
tr:D4JA74_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.81	589	364	21	7	566	4	548	7e-38	158
rs:WP_002609437	DNA topoisomerase III [[Clostridium] innocuum].	26.31	555	357	17	5	531	3	533	7e-38	159
rs:WP_042688348	hypothetical protein [Candidatus Glomeribacter gigasporarum].	28.27	428	275	15	43	452	23	436	7e-38	155
rs:WP_039433724	DNA topoisomerase I [Porphyromonas gulae].	26.62	556	336	20	7	531	4	518	7e-38	158
rs:WP_005834124	DNA topoisomerase I [Bacteroides uniformis].	26.74	576	361	19	4	552	1	542	8e-38	158
rs:WP_022524170	DNA topoisomerase III [Halomonas sp. A3H3].	27.46	590	367	22	1	546	1	573	8e-38	159
rs:WP_013330742	MULTISPECIES: topoisomerase IA [Enterococcus].	31.67	420	248	16	166	563	45	447	8e-38	157
tr:W4V045_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE86442.1};	28.06	474	307	12	97	558	7	458	8e-38	157
rs:WP_015497327	DNA recombination protein RmuC [Octadecabacter arcticus].	27.54	552	339	20	7	531	6	523	8e-38	158
rs:WP_000520743	DNA topoisomerase I [Bacillus cereus].	27.29	568	341	15	5	539	4	532	9e-38	159
rs:WP_036874401	DNA topoisomerase I, partial [Prevotella nigrescens].	27.12	520	338	14	43	543	8	505	9e-38	158
tr:V8CKV1_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.12	520	338	14	43	543	7	504	9e-38	158
tr:E8REX8_DESPD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.61	612	389	23	5	592	4	585	9e-38	159
tr:H2A926_STRMD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.73	618	398	20	7	607	5	578	9e-38	157
rs:WP_004584872	DNA topoisomerase [Porphyromonas gingivalis].	26.22	576	360	16	5	552	3	541	9e-38	158
rs:WP_024346744	DNA topoisomerase III [[Clostridium] methoxybenzovorans].	25.61	617	362	22	3	532	2	608	1e-37	158
rs:WP_047338920	hypothetical protein [Enterococcus cecorum].	26.28	567	342	21	7	544	5	524	1e-37	158
rs:WP_002166603	DNA topoisomerase I [Bacillus cereus].	27.24	558	354	13	5	539	4	532	1e-37	159
rs:WP_032585411	DNA topoisomerase I [Bacteroides fragilis].	27.11	557	352	18	4	539	1	524	1e-37	158
rs:WP_032131825	DNA topoisomerase I [Weeksella sp. FF8].	28.10	580	339	20	4	550	1	535	1e-37	158
rs:WP_005927750	DNA topoisomerase III [Faecalibacterium prausnitzii].	26.16	627	384	24	3	603	2	575	1e-37	158
tr:A0A0C8ZUT9_SALTI	SubName: Full=TopB_3 protein {ECO:0000313|EMBL:CEU15733.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEU15733.1};	28.03	528	334	14	47	544	5	516	1e-37	158
rs:WP_016316298	DNA topoisomerase III [Anaerotruncus sp. G3(2012)].	26.71	569	354	19	3	550	2	528	1e-37	158
rs:WP_033951578	DNA topoisomerase III [Pseudomonas aeruginosa].	25.29	609	397	15	7	573	4	596	1e-37	158
rs:WP_043770622	DNA topoisomerase III [Desulfobulbus propionicus].	27.61	612	389	23	5	592	16	597	1e-37	159
rs:WP_046400357	DNA topoisomerase III, partial [Staphylococcus aureus].	27.27	462	293	15	7	457	5	434	1e-37	155
tr:J7YG53_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.06	558	355	13	5	539	4	532	1e-37	159
rs:WP_041639329	DNA topoisomerase III, partial [Anoxybacillus flavithermus].	31.58	342	205	11	7	343	5	322	1e-37	152
rs:WP_026513782	DNA topoisomerase III [Butyrivibrio sp. LB2008].	25.74	606	379	19	8	553	7	601	1e-37	158
tr:T0XU08_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.21	357	217	11	200	539	20	368	1e-37	156
rs:WP_026713482	DNA topoisomerase I [Flavobacterium daejeonense].	27.04	551	346	17	4	531	1	518	1e-37	157
rs:WP_026713731	DNA topoisomerase I [Flavobacterium daejeonense].	27.45	550	345	18	4	531	1	518	1e-37	157
rs:WP_024727418	hypothetical protein [Clostridiales bacterium VE202-09].	25.48	577	392	17	43	606	66	617	1e-37	158
rs:WP_018593291	DNA topoisomerase III [Blautia producta].	26.26	556	309	16	7	539	4	481	1e-37	157
rs:WP_018595759	DNA topoisomerase III [Blautia producta].	26.67	570	353	20	3	550	2	528	1e-37	157
rs:WP_033716935	DNA topoisomerase III, partial [Bacillus cereus].	31.77	362	201	13	213	548	17	358	1e-37	156
rs:WP_004051183	DNA topoisomerase III [Lactobacillus murinus].	27.42	558	324	21	7	544	5	501	1e-37	157
rs:WP_034020521	DNA topoisomerase III [Pseudomonas aeruginosa].	25.29	609	397	15	7	573	4	596	1e-37	158
tr:A0A0B6X7U4_XENBV	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	37.22	266	154	7	308	563	171	433	1e-37	156
rs:WP_018920050	DNA topoisomerase I [Prevotella oris].	24.49	633	411	19	4	602	1	600	1e-37	157
tr:J8ACM7_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.30	356	207	13	213	548	31	372	1e-37	156
rs:WP_028504491	hypothetical protein [Ruminococcus albus].	28.91	543	336	15	7	540	4	505	1e-37	157
rs:WP_022409634	DNA topoisomerase [Clostridium sp. CAG:354].	28.65	569	342	22	7	546	6	539	1e-37	157
rs:WP_004364188	MULTISPECIES: DNA topoisomerase I [Prevotella].	25.59	551	348	16	5	531	3	515	1e-37	157
rs:WP_033119050	DNA topoisomerase III [Intestinimonas butyriciproducens].	25.20	627	393	21	1	601	1	577	1e-37	157
tr:H1HVV1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.84	592	346	20	7	547	6	555	1e-37	156
rs:WP_013555135	DNA topoisomerase [Bacillus thuringiensis].	29.58	453	283	14	101	531	1	439	1e-37	157
rs:WP_028901949	DNA topoisomerase III [Prevotella corporis].	25.90	583	337	21	8	531	5	551	1e-37	157
rs:WP_000520756	DNA topoisomerase I [Bacillus cereus].	27.51	527	334	12	43	550	46	543	1e-37	159
rs:WP_006573547	hypothetical protein [Pseudoflavonifractor capillosus].	26.65	499	321	14	7	491	4	471	1e-37	155
rs:WP_000604074	DNA topoisomerase III [Salmonella enterica].	25.28	617	384	17	8	572	5	596	1e-37	157
rs:WP_031908286	DNA topoisomerase III, partial [Staphylococcus aureus].	28.04	542	339	18	14	531	1	515	1e-37	157
rs:WP_034073868	DNA topoisomerase III [Pseudomonas aeruginosa].	25.33	608	396	15	8	573	5	596	2e-37	157
rs:WP_002191962	DNA topoisomerase I [Bacillus cereus].	27.42	558	353	14	5	539	4	532	2e-37	159
rs:WP_017643219	DNA topoisomerase [Streptococcus agalactiae].	26.11	563	363	18	7	557	5	526	2e-37	156
rs:WP_039419382	DNA topoisomerase I [Porphyromonas gulae].	27.82	568	354	20	4	550	1	533	2e-37	157
rs:WP_009131566	DNA topoisomerase III [Bacteroides oleiciplenus].	25.81	558	364	18	1	531	1	535	2e-37	157
rs:WP_014791711	DNA topoisomerase [Ornithobacterium rhinotracheale].	26.19	607	379	22	4	579	1	569	2e-37	157
rs:WP_021897294	DNA topoisomerase III [Prevotella sp. CAG:924].	25.88	568	347	17	8	531	5	542	2e-37	157
rs:WP_045152427	DNA topoisomerase III, partial [Escherichia coli].	30.05	416	264	11	7	410	4	404	2e-37	153
rs:WP_005364064	DNA topoisomerase III [Eubacterium ventriosum].	28.00	450	289	14	7	429	5	446	2e-37	157
rs:WP_004362423	DNA topoisomerase III [Prevotella nigrescens].	24.80	633	409	19	4	602	1	600	2e-37	157
rs:WP_018910191	DNA topoisomerase I [Prevotella veroralis].	25.70	572	357	19	5	550	3	532	2e-37	157
rs:WP_021676799	DNA topoisomerase [Porphyromonas gingivalis].	24.33	633	412	19	4	602	1	600	2e-37	157
rs:WP_037315920	DNA topoisomerase I [Salegentibacter sp. Hel_I_6].	27.59	551	343	19	4	531	1	518	2e-37	157
rs:WP_042967269	DNA topoisomerase III [Escherichia coli].	25.24	622	378	18	8	572	5	596	2e-37	157
rs:WP_008688070	DNA topoisomerase III [Eubacterium sp. 3_1_31].	25.43	633	384	20	7	607	4	580	2e-37	157
rs:WP_005776763	DNA topoisomerase I [Bacteroides fragilis].	26.85	555	356	16	4	539	1	524	2e-37	157
rs:WP_000520754	DNA topoisomerase I [Bacillus cereus].	27.71	516	325	12	43	539	46	532	2e-37	159
rs:WP_020561698	hypothetical protein [Methylosarcina fibrata].	28.36	543	341	21	4	531	1	510	2e-37	158
rs:WP_047345337	DNA topoisomerase III [Enterobacter sp. GN03164].	25.28	617	384	17	8	572	5	596	2e-37	157
rs:WP_036894232	DNA topoisomerase I [Prevotella sp. S7-1-8].	25.43	578	359	17	5	550	3	540	2e-37	157
rs:WP_009683127	DNA topoisomerase III, partial [Pseudomonas sp. TJI-51].	33.21	262	164	5	7	268	4	254	2e-37	149
tr:A0A0B4Y581_9PROT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AJD54325.1};	26.75	587	337	20	1	531	1	550	2e-37	158
rs:WP_032542359	DNA topoisomerase I [Bacteroides fragilis].	25.91	548	347	14	8	531	5	517	2e-37	157
rs:WP_036617832	DNA topoisomerase I [Parabacteroides distasonis].	26.79	560	350	19	4	539	1	524	2e-37	157
rs:WP_026748846	DNA topoisomerase III [Leptotrichia trevisanii].	27.59	609	374	25	7	589	5	572	2e-37	157
rs:WP_000520740	DNA topoisomerase I [Bacillus cereus].	27.06	558	355	13	5	539	4	532	2e-37	158
rs:WP_004380945	DNA topoisomerase I [Prevotella oulorum].	25.54	552	345	16	7	531	5	517	2e-37	157
rs:WP_021444245	hypothetical protein, partial [Pseudomonas sp. EGD-AK9].	31.07	354	218	9	198	530	4	352	2e-37	155
tr:C3FBJ1_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.52	516	326	12	43	539	46	532	2e-37	158
rs:WP_005643883	DNA topoisomerase I [Parabacteroides merdae].	25.04	611	394	15	4	592	1	569	2e-37	157
tr:D4LWP6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.22	567	358	20	7	550	6	529	2e-37	157
tr:M7NHP8_9BACT	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EMR01315.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EMR01315.1};	28.29	456	283	12	94	531	5	434	2e-37	156
rs:WP_001235768	DNA topoisomerase III [Escherichia coli].	26.80	612	401	19	7	590	4	596	2e-37	157
tr:A0A0D0HY40_BACTM	SubName: Full=Bacillus thuringiensis serovar morrisoni strain HD 600 BG10.Contig244, whole genome shotgun sequence {ECO:0000313|EMBL:KIP25139.1};	32.16	342	204	11	7	344	6	323	2e-37	151
rs:WP_011191426	DNA topoisomerase III [Yersinia pseudotuberculosis].	25.45	605	396	17	7	573	4	591	3e-37	157
rs:WP_036857240	DNA topoisomerase I [Prevotella denticola].	25.80	566	340	17	5	531	3	527	3e-37	157
rs:WP_024728265	MULTISPECIES: DNA topoisomerase III [unclassified Clostridiales (miscellaneous)].	25.08	630	390	20	7	607	4	580	3e-37	156
tr:C0QUY8_PERMH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.70	543	332	20	7	531	4	498	3e-37	158
rs:WP_004308419	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.04	611	394	15	4	592	1	569	3e-37	157
tr:R8CKW2_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.88	558	356	12	5	539	4	532	3e-37	158
rs:WP_010008973	DNA topoisomerase III [Lactobacillus coryniformis].	25.80	566	360	17	5	563	3	515	3e-37	156
rs:WP_014611673	DNA topoisomerase [Shewanella putrefaciens].	26.58	568	359	16	7	531	4	556	3e-37	157
rs:WP_022638687	topoisomerase IA [Lactobacillus plantarum].	27.97	590	372	19	5	566	3	567	3e-37	157
rs:WP_024566104	DNA topoisomerase I, partial [Elizabethkingia anophelis].	26.83	574	358	20	4	552	1	537	3e-37	156
rs:WP_047209062	DNA topoisomerase [Streptococcus agalactiae].	26.94	568	345	19	5	553	3	519	3e-37	155
rs:WP_003105435	DNA topoisomerase [Streptococcus parauberis].	27.30	564	353	18	7	557	5	524	3e-37	155
tr:A0A091BZB1_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.00	527	319	19	41	550	1	473	3e-37	156
tr:N0DX73_STRPY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.64	563	360	18	7	557	20	541	3e-37	155
rs:WP_000520727	DNA topoisomerase I [Bacillus anthracis].	26.71	629	398	19	5	606	4	596	3e-37	158
rs:WP_024566642	DNA topoisomerase I [Elizabethkingia anophelis].	26.88	558	338	18	4	531	1	518	4e-37	156
rs:WP_016317940	DNA topoisomerase III [Anaerotruncus sp. G3(2012)].	25.20	611	382	22	7	590	4	566	4e-37	156
rs:WP_002353593	DNA topoisomerase, partial [Enterococcus faecium].	28.70	439	282	14	5	429	3	424	4e-37	153
rs:WP_025067905	DNA topoisomerase I [Prevotella denticola].	26.66	574	349	20	5	550	3	532	4e-37	156
rs:WP_007046111	DNA topoisomerase [Subdoligranulum variabile].	26.65	499	321	13	7	491	4	471	4e-37	154
rs:WP_044345686	DNA topoisomerase III, partial [Pseudomonas meliae].	29.31	464	282	16	8	452	5	441	4e-37	154
rs:WP_018362612	DNA topoisomerase I [Prevotella nanceiensis].	25.96	570	358	18	5	550	3	532	4e-37	156
rs:WP_033701090	DNA topoisomerase III, partial [Enterococcus faecium].	25.86	584	363	19	43	601	17	555	4e-37	156
rs:WP_043810271	DNA topoisomerase [Rubrivivax gelatinosus].	28.60	556	346	18	7	536	6	536	4e-37	157
rs:WP_008689666	DNA topoisomerase III [Eubacterium sp. 3_1_31].	26.71	569	354	19	3	550	2	528	4e-37	156
rs:WP_027384303	DNA topoisomerase I [Chryseobacterium caeni].	25.73	618	388	19	4	588	1	580	4e-37	156
tr:A0A084IJ20_9GAMM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KEZ76704.1};	33.61	241	150	3	329	559	1	241	4e-37	151
rs:WP_002204216	DNA topoisomerase I [Bacillus cereus].	26.88	558	356	12	5	539	4	532	4e-37	157
rs:WP_002187829	DNA topoisomerase I [Bacillus cereus].	26.88	558	356	14	5	539	4	532	4e-37	157
rs:WP_044243489	DNA topoisomerase III, partial [Pantoea stewartii].	27.43	565	365	16	8	544	6	553	4e-37	155
rs:WP_003002368	DNA topoisomerase [Sphingobacterium spiritivorum].	26.88	558	338	18	4	531	1	518	4e-37	156
rs:WP_000520741	DNA topoisomerase I [Bacillus cereus].	26.70	558	357	13	5	539	4	532	4e-37	157
rs:WP_032849733	DNA topoisomerase I [Bacteroides sp. 2_2_4].	27.08	469	297	14	97	550	35	473	4e-37	155
gp:AE011190_192	DNA topoisomerase [Bacillus anthracis str. A2012]	26.71	629	398	19	5	606	11	603	4e-37	157
tr:A0A0E0W8Z3_BACAN	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:AFH87063.1};	26.71	629	398	19	5	606	15	607	5e-37	157
tr:C3R196_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.08	469	297	14	97	550	53	491	5e-37	155
rs:WP_035393821	DNA topoisomerase III, partial [Faecalibacterium prausnitzii].	28.31	498	315	14	7	491	10	478	5e-37	153
rs:WP_002169636	DNA topoisomerase I [Bacillus cereus].	27.24	558	354	14	5	539	4	532	5e-37	157
rs:WP_005819871	DNA topoisomerase I [Bacteroides fragilis].	25.50	549	364	12	8	539	5	525	5e-37	156
rs:WP_038267162	DNA topoisomerase III [Xenorhabdus cabanillasii].	26.36	497	333	11	94	563	18	508	5e-37	155
rs:WP_008982747	DNA topoisomerase III [Ruminococcaceae bacterium D16].	25.78	609	386	22	3	590	2	565	5e-37	155
rs:WP_041619455	DNA topoisomerase III, partial [Paenibacillus mucilaginosus].	27.71	462	300	12	5	459	3	437	5e-37	153
rs:WP_022053972	DNA topoisomerase III [Bacteroides plebeius CAG:211].	27.04	577	333	21	7	531	2	542	5e-37	156
rs:WP_046960179	DNA topoisomerase I [Bacillus cereus].	27.24	558	354	14	5	539	4	532	5e-37	157
rs:WP_035458073	DNA topoisomerase I [Bacteroides uniformis].	27.13	575	358	20	4	552	1	540	5e-37	155
tr:R9HYZ0_BACUN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS06385.1};	27.13	575	358	20	4	552	30	569	6e-37	156
rs:WP_033126088	DNA topoisomerase III [Eubacterium sp. ER2].	25.47	589	366	20	7	566	4	548	6e-37	155
rs:WP_044192291	DNA topoisomerase I [Parabacteroides gordonii].	26.64	533	336	16	43	552	22	522	6e-37	155
rs:WP_000520737	DNA topoisomerase I [Bacillus thuringiensis].	26.54	569	366	13	5	550	4	543	6e-37	157
rs:WP_047334070	hypothetical protein [Enterococcus cecorum].	26.57	572	334	24	7	544	5	524	6e-37	156
rs:WP_006844378	DNA topoisomerase I [Dysgonomonas mossii].	25.09	550	359	16	4	531	1	519	6e-37	155
rs:WP_000520755	DNA topoisomerase I [Bacillus thuringiensis].	27.13	527	336	12	43	550	46	543	7e-37	157
rs:WP_042335867	DNA topoisomerase III [Candidatus Accumulibacter sp. BA-92].	27.51	578	362	20	7	550	6	560	7e-37	157
rs:WP_002585004	MULTISPECIES: DNA topoisomerase III [Clostridiales].	24.72	627	396	21	7	607	4	580	7e-37	155
rs:WP_008775022	DNA topoisomerase I [Bacteroides sp. 2_2_4].	26.24	564	368	19	4	550	1	533	7e-37	155
rs:WP_015851562	DNA topoisomerase type IA central domain-containing protein [Desulfovibrio salexigens].	27.18	585	382	18	7	567	4	568	7e-37	155
rs:WP_039421179	DNA topoisomerase I [Porphyromonas gulae].	24.92	634	407	20	4	602	1	600	8e-37	155
rs:WP_042986068	DNA topoisomerase I, partial [Bacteroides fragilis].	26.16	558	368	16	50	591	1	530	8e-37	155
rs:WP_036927629	DNA topoisomerase I, partial [Prevotella timonensis].	25.31	569	371	16	5	550	3	540	8e-37	155
rs:WP_024343926	DNA topoisomerase [Streptococcus equinus].	26.02	565	361	19	7	557	5	526	8e-37	154
rs:WP_033678243	DNA topoisomerase I [Bacillus gaemokensis].	25.76	621	396	17	5	597	4	587	8e-37	157
rs:WP_040087766	DNA topoisomerase [Lactococcus garvieae].	27.30	564	353	18	7	557	5	524	8e-37	154
tr:E7S6H7_STRAG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.65	620	396	21	7	607	12	585	8e-37	154
tr:A0A0C2D1G0_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.32	589	360	18	5	546	3	564	8e-37	157
rs:WP_001235769	hypothetical protein [Escherichia coli].	27.01	585	363	18	8	544	5	573	8e-37	155
rs:WP_013632654	DNA topoisomerase [Pedobacter saltans].	26.70	558	339	18	4	531	1	518	9e-37	155
rs:WP_004234233	DNA topoisomerase III [Streptococcus parauberis].	26.75	572	367	16	7	569	5	533	9e-37	154
rs:WP_031537411	DNA topoisomerase III, partial [Bacillus sp. MB2021].	29.95	394	227	15	7	385	5	364	9e-37	150
rs:WP_024295612	MULTISPECIES: DNA topoisomerase III [Lachnoclostridium].	25.45	617	363	22	3	532	2	608	9e-37	155
rs:WP_002978408	MULTISPECIES: DNA topoisomerase [Chryseobacterium].	27.19	559	335	18	4	531	1	518	9e-37	155
rs:WP_005334803	DNA topoisomerase III [Dorea formicigenerans].	25.64	589	365	20	7	566	4	548	9e-37	155
rs:WP_016513361	DNA topoisomerase III [Bacillus cereus].	26.88	558	356	13	5	539	4	532	9e-37	156
rs:WP_019842535	hypothetical protein [Escherichia coli].	27.05	584	364	18	8	544	5	573	9e-37	155
rs:WP_002960235	DNA topoisomerase III [Streptococcus sobrinus].	25.93	567	350	18	5	550	3	520	9e-37	154
rs:WP_017768605	DNA topoisomerase [Streptococcus agalactiae].	25.75	563	365	18	7	557	5	526	1e-36	154
rs:WP_019484713	hypothetical protein, partial [Pseudomonas aeruginosa].	34.78	253	150	5	312	552	2	251	1e-36	150
rs:WP_000876323	DNA topoisomerase [Streptococcus agalactiae].	25.65	620	396	21	7	607	5	578	1e-36	154
rs:WP_016102507	DNA topoisomerase III [Bacillus cereus].	26.70	558	357	14	5	539	4	532	1e-36	156
rs:WP_000604073	hypothetical protein [Escherichia coli].	25.08	622	379	18	8	572	5	596	1e-36	155
rs:WP_026824282	DNA topoisomerase III, partial [Arsenophonus nasoniae].	26.55	452	305	8	103	532	21	467	1e-36	154
rs:WP_043013020	DNA topoisomerase III [Clostridium perfringens].	25.85	561	373	17	7	548	5	541	1e-36	155
tr:B1BR51_CLOPF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.85	561	373	17	7	548	4	540	1e-36	155
rs:WP_033728948	DNA topoisomerase I [Bacillus weihenstephanensis].	26.47	563	362	13	5	544	4	537	1e-36	156
rs:WP_025494540	DNA topoisomerase III, partial [Lachnospiraceae bacterium VE202-12].	28.45	457	288	14	2	452	3	426	1e-36	152
rs:WP_021624136	DNA topoisomerase [Aneurinibacillus aneurinilyticus].	28.14	558	341	23	5	550	3	512	1e-36	154
rs:WP_026712906	DNA topoisomerase I [Flavobacterium daejeonense].	26.70	558	339	18	4	531	1	518	1e-36	154
tr:A0A0B3AS91_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.44	543	314	19	7	531	112	592	1e-36	155
rs:WP_034070008	DNA topoisomerase III [Pseudomonas aeruginosa].	25.29	613	392	17	7	573	4	596	1e-36	155
gp:CP008816_932	DNA topoisomerase III family protein [Enterococcus faecalis ATCC 29212]	26.53	524	316	17	41	548	1	471	1e-36	154
rs:WP_012744292	MULTISPECIES: DNA topoisomerase III [Clostridiales].	25.20	627	393	19	7	607	4	580	1e-36	154
rs:WP_038654227	DNA topoisomerase I [Mucinivorans hirudinis].	26.64	563	364	18	4	550	1	530	1e-36	154
rs:WP_016107050	DNA topoisomerase III [Bacillus cereus].	26.51	611	393	16	5	590	4	583	1e-36	156
rs:WP_019485491	hypothetical protein, partial [Pseudomonas aeruginosa].	34.78	253	150	5	312	552	2	251	1e-36	150
rs:WP_009009747	DNA topoisomerase [Coprobacillus sp. D7].	27.36	614	384	22	7	590	4	585	1e-36	155
gp:CP001927_17	DNA topoisomerase III [Escherichia coli Xuzhou21]	25.08	622	379	18	8	572	53	644	2e-36	155
rs:WP_035620641	DNA topoisomerase I [Flavobacterium hydatis].	27.68	578	344	19	4	550	1	535	2e-36	154
rs:WP_002094784	DNA topoisomerase I [Bacillus cereus].	26.74	546	362	14	5	534	4	527	2e-36	155
rs:WP_029662198	DNA topoisomerase III [Streptococcus agalactiae].	25.40	618	400	21	7	607	12	585	2e-36	153
rs:WP_040343003	DNA topoisomerase III, partial [Bacillus nealsonii].	30.26	390	231	15	7	385	5	364	2e-36	150
rs:WP_025279158	DNA topoisomerase I [Barnesiella viscericola].	26.57	572	359	18	7	552	4	540	2e-36	154
rs:WP_025070722	DNA topoisomerase I [Prevotella oulorum].	24.33	633	412	19	4	602	1	600	2e-36	154
rs:WP_000520739	DNA topoisomerase I [Bacillus cereus].	26.88	573	360	15	5	547	4	547	2e-36	155
tr:S4W680_STRAG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.84	565	362	19	7	557	5	526	2e-36	153
rs:WP_005344197	DNA topoisomerase III [[Eubacterium] hallii].	25.20	627	393	19	7	607	4	580	2e-36	154
rs:WP_008566167	DNA topoisomerase I [Prevotella maculosa].	26.08	556	345	18	5	531	3	521	2e-36	154
rs:WP_009300879	DNA topoisomerase [Coprobacillus sp. 3_3_56FAA].	27.36	614	384	22	7	590	4	585	2e-36	155
rs:WP_034500952	hypothetical protein, partial [Butyrivibrio hungatei].	25.74	606	379	19	8	553	7	601	2e-36	154
rs:WP_031921360	DNA topoisomerase III, partial [Staphylococcus aureus].	28.04	403	252	13	170	559	14	391	2e-36	150
rs:WP_010752776	DNA topoisomerase III [Enterococcus asini].	27.81	561	330	20	7	550	6	508	2e-36	154
rs:WP_043793203	DNA topoisomerase III, partial [Delftia tsuruhatensis].	27.83	557	335	22	56	568	1	534	2e-36	155
rs:WP_035778518	DNA topoisomerase III [Butyrivibrio sp. MC2013].	25.16	632	378	19	8	553	6	628	2e-36	154
rs:WP_015495977	DNA recombination protein RmuC [Octadecabacter arcticus].	26.40	553	348	16	5	531	4	523	2e-36	154
rs:WP_034462255	hypothetical protein, partial [Butyrivibrio sp. AE3003].	25.74	606	379	19	8	553	7	601	2e-36	154
tr:R9C509_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	30.26	390	231	15	7	385	5	364	2e-36	149
rs:WP_021560353	hypothetical protein [Escherichia coli].	27.23	584	363	18	8	544	5	573	2e-36	154
rs:WP_032834767	DNA topoisomerase [Fusobacterium sp. OBRC1].	27.07	580	367	18	7	561	4	552	2e-36	154
rs:WP_042060806	DNA topoisomerase III [Escherichia coli].	25.08	622	379	18	8	572	5	596	2e-36	154
rs:WP_021914626	DNA topoisomerase [Firmicutes bacterium CAG:24].	25.80	593	342	20	43	554	12	587	2e-36	154
rs:WP_013499826	DNA topoisomerase III [Ruminococcus albus].	26.09	571	357	18	7	546	5	541	2e-36	154
rs:WP_012816677	DNA topoisomerase III [Staphylococcus aureus].	29.75	474	301	15	5	466	3	456	2e-36	151
rs:WP_021639605	DNA topoisomerase [Clostridium sp. KLE 1755].	25.71	560	362	15	7	550	4	525	3e-36	154
rs:WP_004341621	DNA topoisomerase I [Prevotella buccae].	24.33	633	412	19	4	602	1	600	3e-36	154
rs:WP_005832597	DNA topoisomerase I [Bacteroides uniformis].	25.21	599	393	16	1	584	1	559	3e-36	154
rs:WP_016128043	DNA topoisomerase III [Bacillus cereus].	26.52	558	358	13	5	539	4	532	3e-36	155
rs:WP_028513383	DNA topoisomerase III [Ruminococcaceae bacterium AE2021].	26.68	551	340	20	7	535	4	512	3e-36	154
rs:WP_018919957	DNA topoisomerase I [Prevotella oris].	25.74	571	360	17	5	550	3	534	3e-36	154
rs:WP_006842135	DNA topoisomerase I [Dysgonomonas mossii].	25.44	574	369	18	5	550	3	545	3e-36	154
rs:WP_004352634	DNA topoisomerase I [Prevotella denticola].	25.14	553	348	17	5	531	3	515	3e-36	154
rs:WP_019781775	hypothetical protein [Streptococcus sobrinus].	26.28	567	348	18	5	550	3	520	3e-36	152
rs:WP_008780590	DNA topoisomerase I [Bacteroides sp. 3_1_19].	24.71	611	396	15	4	592	1	569	3e-36	154
rs:WP_002163405	DNA topoisomerase III [Bacillus cereus].	26.82	619	386	25	7	603	6	579	3e-36	153
tr:D4J464_9FIRM	RecName: Full=DNA topoisomerase 3 {ECO:0000256|HAMAP-Rule:MF_00953}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00953, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase III {ECO:0000256|HAMAP-Rule:MF_00953};	25.64	550	336	17	5	530	3	503	3e-36	154
rs:WP_034468441	hypothetical protein, partial [Butyrivibrio sp. AE2005].	25.74	606	379	19	8	553	7	601	3e-36	153
rs:WP_005957513	DNA topoisomerase III [Fusobacterium necrophorum].	25.31	565	358	16	4	540	1	529	3e-36	154
rs:WP_033066679	hypothetical protein [Clostridium botulinum].	27.14	549	344	21	7	533	5	519	3e-36	154
rs:WP_044423261	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	32.69	309	186	8	8	309	5	298	3e-36	147
rs:WP_033405780	hypothetical protein, partial [Kiloniella laminariae].	26.39	576	346	19	5	530	3	550	3e-36	153
rs:WP_031915414	DNA topoisomerase III, partial [Staphylococcus aureus].	28.04	403	252	13	170	559	24	401	4e-36	150
rs:WP_043010875	DNA topoisomerase III [Campylobacter jejuni].	26.65	454	289	11	136	559	12	451	4e-36	152
rs:WP_022954113	conjugal transfer protein TraE [Leucothrix mucor].	26.74	576	356	18	8	548	5	549	4e-36	154
rs:WP_026726938	DNA topoisomerase I [Flavobacterium denitrificans].	27.65	575	348	19	4	550	1	535	4e-36	153
rs:WP_046308328	hypothetical protein [Lactobacillus apis].	26.19	565	375	13	5	540	3	554	4e-36	154
rs:WP_005943447	DNA topoisomerase III [Faecalibacterium prausnitzii].	25.49	612	386	23	3	590	2	567	4e-36	153
rs:WP_023058387	MULTISPECIES: DNA topoisomerase [Prevotella].	24.88	623	399	20	4	591	1	589	4e-36	153
rs:WP_043511603	DNA topoisomerase III, partial [Halomonas sp. BC04].	31.25	304	199	7	285	582	2	301	4e-36	149
rs:WP_000520742	hypothetical protein [Bacillus cereus].	26.19	569	368	13	5	550	4	543	4e-36	154
rs:WP_019777165	hypothetical protein [Streptococcus sobrinus].	26.28	567	348	18	5	550	3	520	4e-36	152
rs:WP_033608220	topoisomerase I, partial [Lactobacillus plantarum].	29.14	580	377	16	5	566	3	566	5e-36	152
rs:WP_015769197	DNA topoisomerase III [Leptotrichia buccalis].	27.27	561	349	21	7	548	5	525	5e-36	153
tr:R9M7W1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	24.13	605	396	20	7	590	4	566	5e-36	153
sp:TOP1_BACAN	RecName: Full=DNA topoisomerase 1; EC=5.99.1.2; AltName: Full=DNA topoisomerase I; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	27.09	587	369	18	43	606	29	579	5e-36	154
rs:WP_035393414	DNA topoisomerase III, partial [Faecalibacterium prausnitzii].	26.65	499	317	12	7	487	4	471	5e-36	150
rs:WP_042688973	DNA topoisomerase I [Thermococcus nautili].	26.19	611	381	19	4	589	2	567	5e-36	153
rs:WP_040654648	DNA topoisomerase III [Oscillibacter sp. 1-3].	24.13	605	396	20	7	590	6	568	5e-36	153
rs:WP_041311293	hypothetical protein, partial [Sebaldella termitidis].	26.30	578	358	16	7	549	4	548	5e-36	152
tr:W4QCD4_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.92	391	249	11	3	389	2	371	5e-36	149
tr:C7H1C5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.65	499	317	12	7	487	4	471	5e-36	150
rs:WP_035102953	DNA topoisomerase III, partial [Coprococcus sp. HPP0074].	26.80	459	281	14	7	450	4	422	5e-36	150
rs:WP_039431396	DNA topoisomerase I [Porphyromonas gulae].	27.03	566	361	18	4	550	1	533	5e-36	153
rs:WP_017168920	hypothetical protein, partial [Xanthomonas axonopodis].	28.65	363	235	10	7	361	4	350	6e-36	147
rs:WP_041992809	DNA topoisomerase I, partial [Capnocytophaga cynodegmi].	27.55	548	345	19	4	531	1	516	6e-36	151
rs:WP_016526770	DNA topoisomerase [Lactobacillus plantarum].	29.73	555	358	15	5	544	3	540	6e-36	153
rs:WP_032948603	DNA topoisomerase I, partial [Bacteroides vulgatus].	27.08	480	307	14	4	469	1	451	6e-36	150
tr:A0A069YSN5_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.98	504	318	16	7	486	4	486	6e-36	150
rs:WP_040077835	DNA topoisomerase III, partial [Escherichia coli].	32.43	296	188	5	8	301	5	290	7e-36	147
rs:WP_040109967	hypothetical protein [Clostridium botulinum].	27.11	546	348	20	7	533	5	519	7e-36	153
rs:WP_039372716	DNA topoisomerase I [Chryseobacterium taiwanense].	26.32	551	350	16	4	531	1	518	7e-36	152
tr:A0A0B3AAN5_9ARCH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KHO49463.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHO49463.1};	28.21	468	288	15	97	556	15	442	7e-36	152
rs:WP_032429271	hypothetical protein, partial [Klebsiella pneumoniae].	25.29	526	360	12	7	512	4	516	7e-36	153
tr:D4JW68_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.87	595	382	23	43	607	47	606	7e-36	153
tr:S2YZQ0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.80	459	281	14	7	450	4	422	7e-36	150
tr:F7JRL0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.80	459	281	14	7	450	4	422	8e-36	150
tr:E2XSJ7_PSEFL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFQ63311.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFQ63311.1};	32.25	307	173	8	8	301	5	289	8e-36	146
rs:WP_017168565	hypothetical protein, partial [Xanthomonas axonopodis].	28.53	361	234	10	7	359	4	348	9e-36	147
tr:F3VI83_STREE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.73	449	269	15	7	436	4	411	9e-36	149
rs:WP_031358079	DNA topoisomerase III, partial [Burkholderia sordidicola].	27.24	558	351	18	7	540	5	531	9e-36	151
tr:H6NHR0_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.71	462	300	12	5	459	3	437	9e-36	152
rs:WP_012720245	hypothetical protein [Clostridium botulinum].	26.92	546	349	20	7	533	5	519	9e-36	153
tr:D4E5Q2_SEROD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.18	289	186	6	251	531	11	297	9e-36	149
rs:WP_030032216	hypothetical protein [Clostridium botulinum].	27.27	550	342	23	7	533	5	519	9e-36	153
rs:WP_005935077	DNA topoisomerase III [Faecalibacterium prausnitzii].	25.92	625	382	23	3	590	2	582	1e-35	152
rs:WP_021747026	DNA topoisomerase III [Leptotrichia wadei].	27.27	561	349	21	7	548	5	525	1e-35	152
tr:Q33E26_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.40	553	342	19	7	534	5	517	1e-35	153
rs:WP_012695386	DNA topoisomerase [Lactobacillus brevis].	25.63	558	351	18	7	546	5	516	1e-35	152
rs:WP_046502101	DNA topoisomerase III, partial [Kiloniella sp. P1-1].	27.94	587	349	19	5	552	3	554	1e-35	152
rs:WP_008799769	DNA topoisomerase III [Fusobacterium nucleatum].	26.99	578	349	20	7	548	6	546	1e-35	153
rs:WP_042743737	DNA topoisomerase III, partial [Staphylococcus aureus].	29.98	457	289	14	5	450	3	439	1e-35	149
tr:W4V5H9_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.29	447	280	14	176	603	2	422	1e-35	150
rs:WP_022357530	DNA topoisomerase III [Ruminococcus sp. CAG:379].	26.46	548	341	17	7	531	4	512	1e-35	152
rs:WP_007135634	DNA topoisomerase I [Prevotella salivae].	25.54	560	345	16	5	531	3	523	1e-35	152
rs:WP_046938350	DNA topoisomerase III, partial [Xanthomonas perforans].	28.45	348	224	9	202	531	6	346	1e-35	147
rs:WP_011989128	hypothetical protein [Clostridium kluyveri].	28.30	576	358	19	7	557	4	549	1e-35	152
rs:WP_031872897	DNA topoisomerase III, partial [Staphylococcus aureus].	29.98	457	289	14	5	450	3	439	1e-35	149
tr:I4Z0W6_9RHIZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.30	577	352	19	2	532	6	549	1e-35	150
rs:WP_042260024	DNA topoisomerase III [Clostridium perfringens].	28.08	552	352	17	16	550	1	524	1e-35	152
rs:WP_014118863	DNA topoisomerase III [Oscillibacter valericigenes].	25.54	556	351	16	7	548	4	510	1e-35	151
rs:WP_011988545	DNA topoisomerase III [Yersinia pseudotuberculosis].	28.72	564	349	22	1	536	1	539	1e-35	152
rs:WP_027089858	DNA topoisomerase III [[Clostridium] saccharogumia].	24.80	633	388	20	7	607	4	580	1e-35	152
rs:WP_000520748	DNA topoisomerase I [Bacillus cereus].	27.07	580	368	15	48	606	51	596	1e-35	153
rs:WP_035303104	hypothetical protein, partial [Clostridium sp. HGF2].	27.30	564	347	21	7	550	4	524	1e-35	151
rs:WP_009644006	toprim domain protein, partial [Mogibacterium sp. CM50].	28.74	414	256	11	7	414	4	384	1e-35	147
rs:WP_038700296	DNA topoisomerase I [Sphingobacterium sp. ML3W].	27.70	556	337	19	4	531	1	519	1e-35	152
rs:WP_002164824	DNA topoisomerase III [Bacillus cereus].	26.09	617	393	24	7	603	6	579	1e-35	151
rs:WP_044720911	DNA topoisomerase [Streptococcus suis].	24.96	625	394	22	7	607	5	578	1e-35	150
rs:WP_047094745	DNA topoisomerase I [Chryseobacterium indologenes].	26.52	558	340	18	4	531	1	518	1e-35	151
rs:WP_033694665	DNA topoisomerase III, partial [Bacillus thuringiensis].	31.03	377	235	11	89	450	5	371	1e-35	147
rs:WP_020322465	toprim domain protein, partial [Klebsiella pneumoniae].	29.97	397	251	11	7	391	4	385	2e-35	147
rs:WP_016112277	DNA topoisomerase 1 [Bacillus cereus].	26.71	629	398	17	5	606	4	596	2e-35	152
rs:WP_047090595	DNA topoisomerase III, partial [Escherichia coli].	29.29	437	286	13	7	435	4	425	2e-35	148
tr:A0A073IAB4_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KEJ86500.1};	27.60	558	348	20	4	539	1	524	2e-35	151
rs:WP_033624355	DNA topoisomerase, partial [Enterococcus faecium].	26.22	553	343	19	7	534	5	517	2e-35	152
rs:WP_044167350	DNA topoisomerase III, partial [Staphylococcus aureus].	28.89	398	241	14	7	393	5	371	2e-35	147
rs:WP_000520746	DNA topoisomerase I [Bacillus cereus].	27.07	580	368	15	48	606	51	596	2e-35	152
rs:WP_005935499	DNA topoisomerase III [Faecalibacterium prausnitzii].	25.28	621	391	22	3	590	2	582	2e-35	151
tr:F0Z4H4_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.26	578	353	20	24	534	9	574	2e-35	151
rs:WP_005909733	DNA topoisomerase III [Fusobacterium nucleatum].	26.07	583	369	18	7	561	4	552	2e-35	151
rs:WP_041240562	hypothetical protein, partial [Gordonibacter pamelaeae].	25.13	561	355	19	5	532	3	531	2e-35	151
tr:A0A084ITG9_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.70	558	357	13	5	539	4	532	2e-35	152
rs:WP_006785942	DNA topoisomerase [Turicibacter sanguinis].	25.17	604	397	17	7	587	5	576	2e-35	151
rs:WP_040638147	DNA topoisomerase, partial [Microvirga lotononidis].	25.27	550	345	18	29	532	11	540	2e-35	149
rs:WP_034014014	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	34.17	278	162	7	293	552	1	275	2e-35	147
rs:WP_002338430	DNA topoisomerase III, partial [Enterococcus faecium].	27.35	490	332	13	67	544	1	478	2e-35	150
rs:WP_002311832	DNA topoisomerase [Enterococcus faecium].	26.22	553	343	19	7	534	5	517	2e-35	152
rs:WP_041657828	hypothetical protein [Achromobacter xylosoxidans].	26.40	606	368	23	8	546	13	607	2e-35	151
rs:WP_025068869	DNA topoisomerase I [Bacteroides gallinarum].	26.69	577	354	21	4	550	1	538	2e-35	151
rs:WP_044652667	DNA topoisomerase III, partial [Klebsiella variicola].	32.73	275	174	6	285	552	18	288	2e-35	147
tr:F9EMU8_FUSNU	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EGQ79718.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EGQ79718.1};	24.91	530	336	14	42	539	43	542	2e-35	151
rs:WP_000520747	DNA topoisomerase I [Bacillus cereus].	27.07	580	368	15	48	606	51	596	2e-35	152
rs:WP_002362705	DNA topoisomerase [Enterococcus faecium].	26.22	553	343	19	7	534	5	517	2e-35	152
rs:WP_000520749	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	27.07	580	368	15	48	606	51	596	2e-35	152
rs:WP_002337938	DNA topoisomerase III [Enterococcus faecium].	26.22	553	343	19	7	534	5	517	2e-35	152
rs:WP_043712494	ATP-dependent DNA helicase RecQ, partial [Myxococcus fulvus].	25.97	543	326	16	48	531	1	526	2e-35	153
rs:WP_000520738	DNA topoisomerase I [Bacillus cereus].	26.52	558	358	13	5	539	4	532	2e-35	152
rs:WP_010776949	DNA topoisomerase III [Enterococcus faecium].	26.22	553	343	19	7	534	5	517	2e-35	152
rs:WP_035342059	DNA topoisomerase III, partial [Dickeya sp. DW 0440].	29.52	332	216	10	214	531	1	328	2e-35	148
rs:WP_039420015	DNA topoisomerase I [Porphyromonas gulae].	27.55	548	345	19	4	531	1	516	2e-35	151
rs:WP_016095076	DNA topoisomerase 1 [Bacillus cereus].	26.67	630	397	18	5	606	4	596	2e-35	152
rs:WP_023195012	DNA topoisomerase III, partial [Salmonella enterica].	32.69	260	164	6	300	552	1	256	2e-35	146
tr:E3HYK0_ACHXA	SubName: Full=DNA topoisomerase III 3 {ECO:0000313|EMBL:ADP20154.1}; EC=5.99.1.2 {ECO:0000313|EMBL:ADP20154.1};	26.40	606	368	23	8	546	26	620	2e-35	151
rs:WP_041691717	hypothetical protein, partial [Eggerthella lenta].	25.22	563	353	20	5	532	3	532	3e-35	151
rs:WP_016090829	DNA topoisomerase III [Bacillus cereus].	26.52	558	358	13	5	539	4	532	3e-35	152
rs:WP_036031200	hypothetical protein, partial [Burkholderia gladioli].	28.39	465	290	17	102	543	7	451	3e-35	149
rs:WP_036868535	MULTISPECIES: DNA topoisomerase I [Porphyromonas].	27.06	547	349	17	4	531	1	516	3e-35	150
rs:WP_016274760	DNA topoisomerase III [Bacteroides massiliensis].	26.53	573	364	19	4	552	1	540	3e-35	151
tr:A0A090R3W2_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.68	303	196	7	254	548	1	300	3e-35	147
tr:E4LQP4_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.30	564	347	21	7	550	4	524	3e-35	150
rs:WP_023041758	hypothetical protein [Fusobacterium nucleatum].	25.82	577	378	17	7	561	4	552	3e-35	151
rs:WP_024858121	DNA topoisomerase III [Ruminococcus albus].	25.68	584	367	20	7	557	5	554	3e-35	151
rs:WP_044231743	DNA topoisomerase I [Porphyromonas sp. COT-290 OH3588].	24.61	634	409	20	4	602	1	600	3e-35	150
rs:WP_044797016	DNA topoisomerase I [Bacillus cereus].	26.84	585	363	16	48	606	51	596	3e-35	152
tr:F3GHG4_PSESJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.25	256	161	5	306	549	2	254	3e-35	146
rs:WP_034849209	DNA topoisomerase, partial [Clostridium hydrogeniformans].	26.32	627	384	21	5	590	3	592	3e-35	149
tr:C8WNM4_EGGLE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.22	563	353	20	5	532	3	532	3e-35	151
rs:WP_039311041	DNA topoisomerase III, partial [Pectobacterium atrosepticum].	25.52	576	386	15	7	557	4	561	3e-35	150
rs:WP_044192363	DNA topoisomerase I [Parabacteroides gordonii].	26.35	554	351	17	26	552	5	528	3e-35	150
rs:WP_021107261	type I topoisomease [Clostridium botulinum].	26.52	558	336	20	7	533	5	519	4e-35	151
rs:WP_028086447	DNA topoisomerase III [Dorea longicatena].	26.43	575	339	18	7	552	4	523	4e-35	150
rs:WP_002139803	DNA topoisomerase I [Bacillus cereus].	26.78	631	396	19	5	606	4	597	4e-35	151
rs:WP_003230046	DNA topoisomerase III [Pseudomonas fluorescens].	25.18	560	365	16	8	532	5	545	4e-35	150
rs:WP_040411739	DNA topoisomerase III [[Clostridium] asparagiforme].	24.72	623	380	18	8	553	7	617	4e-35	150
rs:WP_040638921	DNA topoisomerase, partial [Microvirga lotononidis].	26.05	549	342	18	29	532	11	540	4e-35	151
rs:WP_014012324	DNA topoisomerase I [Thermococcus sp. 4557].	27.07	617	368	23	4	589	2	567	4e-35	150
rs:WP_033869006	DNA topoisomerase III, partial [Staphylococcus aureus].	27.23	437	280	13	136	559	7	418	4e-35	149
rs:WP_031794362	DNA topoisomerase III, partial [Staphylococcus aureus].	28.30	417	256	15	7	412	5	389	4e-35	146
rs:WP_022341006	DNA topoisomerase III [Roseburia sp. CAG:309].	26.57	670	407	26	7	606	6	660	4e-35	150
rs:WP_015695732	DNA topoisomerase [Streptococcus infantarius].	24.15	617	409	18	7	607	5	578	5e-35	149
rs:WP_031922918	DNA topoisomerase III, partial [Staphylococcus aureus].	28.64	398	242	14	7	393	5	371	5e-35	146
rs:WP_024526862	hypothetical protein [Lactobacillus brevis].	25.63	558	351	18	7	546	5	516	5e-35	150
tr:C0D086_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.08	602	362	18	8	532	11	600	5e-35	150
rs:WP_044496677	DNA topoisomerase III, partial [Peptoclostridium difficile].	30.00	400	245	13	7	402	4	372	5e-35	146
rs:WP_023161792	DNA topoisomerase [Clostridium autoethanogenum].	27.87	549	346	19	5	533	3	521	5e-35	151
rs:WP_003106651	DNA topoisomerase III [Streptococcus parauberis].	27.13	564	354	18	7	557	5	524	5e-35	149
rs:WP_017144927	DNA topoisomerase [Fusobacterium nucleatum].	25.24	531	335	14	42	540	38	538	5e-35	150
rs:WP_013701945	DNA topoisomerase III [Treponema succinifaciens].	26.64	563	347	21	7	539	3	529	5e-35	150
tr:G4ADB6_AGGAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	37.25	255	137	11	279	518	12	258	5e-35	144
rs:WP_025836956	DNA topoisomerase I [Prevotella scopos].	25.27	550	351	16	5	531	3	515	5e-35	150
rs:WP_003524692	hypothetical protein, partial [[Clostridium] clostridioforme].	27.99	393	246	11	1	389	1	360	5e-35	145
rs:WP_031811100	DNA topoisomerase III, partial [Staphylococcus aureus].	28.64	398	242	14	7	393	5	371	5e-35	145
rs:WP_000520751	DNA topoisomerase I [Bacillus cereus].	27.15	582	365	15	48	606	51	596	5e-35	151
rs:WP_025191329	DNA topoisomerase, partial [Enterococcus faecalis].	26.75	471	292	13	124	563	1	449	5e-35	149
tr:T1ZSD4_STRAP	SubName: Full=Putative DNA topoisomerase III {ECO:0000313|EMBL:AGU81119.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AGU81119.1};	26.12	513	326	14	48	550	17	486	6e-35	148
rs:WP_016270792	DNA topoisomerase III [Bacteroides vulgatus].	26.80	571	355	19	7	550	4	538	6e-35	150
rs:WP_005801814	DNA topoisomerase I [Bacteroides fragilis].	26.66	574	358	19	4	550	1	538	6e-35	150
rs:WP_023039176	hypothetical protein [Fusobacterium nucleatum].	25.90	583	370	18	7	561	4	552	6e-35	150
rs:WP_003308699	DNA topoisomerase III [Bacillus thuringiensis].	25.93	617	394	24	7	603	6	579	6e-35	150
tr:A0A075LS84_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.13	551	338	20	5	539	3	511	6e-35	150
tr:F3GC87_PSESJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.25	256	161	5	306	549	2	254	6e-35	145
rs:WP_012300871	hypothetical protein [Clostridium botulinum].	26.21	557	339	20	7	533	5	519	6e-35	150
rs:WP_042991347	DNA topoisomerase III, partial [Bifidobacterium adolescentis].	26.67	540	307	18	93	579	22	525	6e-35	149
rs:WP_028828555	DNA topoisomerase III [Proteocatella sphenisci].	26.50	585	344	20	7	543	5	551	6e-35	150
rs:XP_001786801	predicted protein [Physcomitrella patens].	28.44	422	241	10	135	532	11	395	7e-35	146
rs:WP_019778497	hypothetical protein [Streptococcus sobrinus].	25.75	567	351	18	5	550	3	520	7e-35	148
rs:WP_016662014	DNA topoisomerase III [Bacteroides stercoris].	27.34	556	352	19	4	539	1	524	7e-35	150
tr:D1AS14_SEBTE	SubName: Full=DNA topoisomerase type IA central domain protein {ECO:0000313|EMBL:ACZ11001.1};	26.30	578	358	16	7	549	4	548	7e-35	150
rs:WP_034054043	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	35.29	255	146	6	8	258	5	244	7e-35	142
rs:WP_000520728	DNA topoisomerase I [Bacillus cereus].	26.87	629	397	20	5	606	4	596	7e-35	150
rs:WP_000520729	DNA topoisomerase I [Bacillus cereus].	27.05	621	406	18	5	606	4	596	7e-35	150
rs:WP_031653318	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	34.09	264	154	6	306	552	3	263	7e-35	145
tr:I4YSH0_9RHIZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.05	549	342	18	29	532	20	549	7e-35	150
rs:WP_025775433	hypothetical protein [Clostridium botulinum].	26.52	558	336	20	7	533	5	519	8e-35	150
rs:WP_014893884	DNA topoisomerase I [Bacillus cereus].	26.42	632	396	19	5	606	4	596	8e-35	150
tr:A0A087DS06_9BIFI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KFI98306.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KFI98306.1};	26.68	581	357	19	7	549	16	565	8e-35	150
rs:WP_033692010	DNA topoisomerase I [Bacillus cereus].	26.87	629	397	20	5	606	4	596	8e-35	150
rs:WP_042797823	hypothetical protein [Achromobacter xylosoxidans].	25.99	604	373	20	8	546	13	607	9e-35	149
rs:WP_041488010	DNA topoisomerase I, partial [Bacillus thuringiensis].	26.80	571	375	19	34	587	38	582	9e-35	148
rs:WP_005945902	hypothetical protein, partial [Blautia hydrogenotrophica].	27.52	556	327	19	1	500	1	536	9e-35	147
tr:R3JUZ9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.46	426	259	12	166	563	46	449	9e-35	148
rs:WP_000520745	DNA topoisomerase I [Bacillus cereus].	26.55	629	399	17	5	606	4	596	9e-35	150
tr:F9MPK7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.19	233	137	5	291	512	2	231	9e-35	141
rs:WP_031826169	DNA topoisomerase III, partial [Staphylococcus aureus].	28.50	393	240	13	7	389	5	366	9e-35	145
rs:WP_027105433	DNA topoisomerase III [Lachnospiraceae bacterium V9D3004].	25.78	640	348	21	8	532	7	634	9e-35	149
rs:WP_000520733	DNA topoisomerase I [Bacillus thuringiensis].	27.17	622	404	18	5	606	4	596	1e-34	150
rs:WP_032568995	DNA topoisomerase I [Bacteroides fragilis].	25.21	583	369	16	7	550	7	561	1e-34	149
rs:WP_002597132	hypothetical protein [Clostridium colicanis].	27.54	501	320	15	116	590	5	488	1e-34	148
rs:WP_021628044	DNA topoisomerase, partial [Capnocytophaga sp. oral taxon 863].	26.86	484	305	12	105	566	14	470	1e-34	147
rs:WP_000520730	DNA topoisomerase I [Bacillus thuringiensis].	27.38	621	404	19	5	606	4	596	1e-34	150
rs:WP_014788241	DNA topoisomerase I [Thermococcus sp. CL1].	25.85	619	373	20	4	589	2	567	1e-34	149
tr:J7HU65_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.80	571	375	19	34	587	38	582	1e-34	149
rs:WP_032599027	DNA topoisomerase I [Bacteroides fragilis].	26.50	566	363	17	7	550	4	538	1e-34	149
rs:WP_033500273	hypothetical protein [Bifidobacterium stercoris].	26.68	581	357	19	7	549	4	553	1e-34	149
rs:WP_000520736	DNA topoisomerase I [Bacillus thuringiensis].	27.10	620	407	19	5	606	4	596	1e-34	150
rs:WP_033694064	DNA topoisomerase III [Bacillus cereus].	26.19	611	384	24	7	595	6	571	1e-34	149
rs:WP_016119511	hypothetical protein, partial [Bacillus cereus].	27.33	505	316	12	5	486	4	480	1e-34	146
rs:WP_002405920	DNA topoisomerase, partial [Enterococcus faecalis].	27.42	485	322	15	5	473	3	473	1e-34	146
rs:WP_033698227	DNA topoisomerase I [Bacillus thuringiensis].	26.97	623	404	20	5	606	4	596	1e-34	150
rs:WP_014121655	DNA topoisomerase I [Thermococcus sp. AM4].	26.18	615	376	20	4	589	2	567	2e-34	149
rs:WP_012025057	DNA topoisomerase [Flavobacterium johnsoniae].	25.66	569	367	17	4	550	1	535	2e-34	149
rs:WP_013438822	DNA topoisomerase III [Edwardsiella tarda].	27.95	458	303	14	8	455	5	445	2e-34	147
rs:WP_042866226	DNA topoisomerase III [Bacillus cereus].	28.98	452	261	15	136	550	7	435	2e-34	148
rs:WP_032944513	DNA topoisomerase I [Bacteroides vulgatus].	25.79	570	368	16	4	550	1	538	2e-34	148
rs:WP_032072421	DNA topoisomerase III [Clostridium botulinum].	26.96	549	345	21	7	533	5	519	2e-34	149
rs:WP_000520750	DNA topoisomerase I [Bacillus thuringiensis].	26.90	580	369	15	48	606	51	596	2e-34	149
rs:WP_046648653	DNA topoisomerase I [Bacillus cereus].	26.42	632	396	19	5	606	4	596	2e-34	149
rs:WP_032585083	MULTISPECIES: DNA topoisomerase I [Bacteroides].	26.62	571	356	19	7	550	4	538	2e-34	148
rs:WP_005921736	DNA topoisomerase III [Faecalibacterium prausnitzii].	27.14	538	343	16	16	539	1	503	2e-34	148
rs:WP_040468959	DNA topoisomerase III, partial [Eubacterium plexicaudatum].	28.57	448	269	12	111	539	1	416	2e-34	147
tr:Q3EKS2_BACTI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.85	412	260	16	7	406	4	398	2e-34	144
rs:WP_033874173	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	31.42	296	182	8	4	293	1	281	2e-34	142
rs:WP_005945111	DNA topoisomerase, partial [Faecalibacterium prausnitzii].	27.48	444	274	12	111	539	17	427	2e-34	145
tr:C6IR36_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EES67056.2};	26.43	575	360	19	3	550	22	560	2e-34	148
tr:X3PRR7_SALEN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	32.71	266	169	6	251	508	2	265	2e-34	141
rs:WP_036844649	DNA topoisomerase I [Porphyromonas sp. COT-108 OH1349].	26.68	566	363	18	4	550	1	533	2e-34	148
rs:WP_043308972	hypothetical protein, partial [Bacillus sp. 7_6_55CFAA_CT2].	27.92	437	286	9	114	539	2	420	2e-34	149
rs:WP_022230671	DNA topoisomerase [Firmicutes bacterium CAG:41].	27.27	561	343	23	7	548	4	518	2e-34	148
rs:WP_032708797	DNA topoisomerase, partial [Pseudomonas syringae].	26.00	627	393	23	7	592	6	602	2e-34	149
rs:WP_022085420	DNA topoisomerase [Roseburia sp. CAG:197].	27.50	509	298	15	110	553	11	513	2e-34	149
tr:V2BXS5_SALDE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.86	384	256	11	7	379	4	377	2e-34	144
rs:WP_034951167	DNA topoisomerase III, partial [Erwinia oleae].	39.27	219	118	4	326	531	1	217	2e-34	143
rs:WP_017643941	DNA topoisomerase [Streptococcus agalactiae].	28.10	452	258	14	107	539	25	428	3e-34	145
rs:WP_025002755	DNA topoisomerase I [Prevotella dentasini].	24.47	658	404	22	4	602	1	624	3e-34	148
rs:WP_006885830	DNA topoisomerase I [Halosimplex carlsbadense].	25.68	549	352	17	7	541	4	510	3e-34	149
rs:WP_039107348	hypothetical protein [Lactobacillus brevis].	25.45	558	352	18	7	546	5	516	3e-34	148
rs:WP_021729338	DNA topoisomerase 1 [Bacillus thuringiensis].	26.97	571	374	19	34	587	38	582	3e-34	149
rs:WP_000520732	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	27.10	620	407	19	5	606	4	596	3e-34	149
tr:A0A0B8QFV7_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.75	400	246	13	7	387	5	388	3e-34	144
tr:W1EWP4_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.74	393	260	12	7	385	4	386	3e-34	144
rs:WP_000520757	DNA topoisomerase I [Bacillus cereus].	26.87	588	385	20	34	602	38	599	3e-34	149
tr:C2FZU9_9SPHI	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEI91545.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EEI91545.1};	29.53	403	240	11	4	389	1	376	3e-34	144
rs:WP_036350533	DNA topoisomerase, partial [Microvirga sp. BSC39].	25.09	550	347	18	29	532	11	541	4e-34	148
rs:WP_012008596	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	26.97	571	374	19	34	587	38	582	4e-34	148
tr:C3DWP7_BACTS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.97	571	374	19	34	587	38	582	4e-34	148
rs:WP_032889348	DNA topoisomerase [Fusobacterium nucleatum].	24.77	533	335	15	42	540	38	538	4e-34	147
rs:WP_011695783	DNA topoisomerase I [Methanosaeta thermophila].	24.47	609	379	20	7	593	4	553	4e-34	147
tr:J8HJV3_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.45	561	366	16	5	548	4	540	4e-34	146
rs:WP_036247157	DNA topoisomerase, partial [Methylobacter sp. BBA5.1].	33.10	290	173	7	279	548	9	297	5e-34	141
rs:WP_009419771	DNA topoisomerase [Capnocytophaga sp. oral taxon 380].	26.76	583	368	19	5	557	4	557	5e-34	147
rs:WP_013238946	hypothetical protein [Clostridium ljungdahlii].	27.77	551	344	20	5	533	3	521	5e-34	148
rs:WP_015283225	DNA topoisomerase I, archaeal [Aciduliprofundum sp. MAR08-339].	25.58	559	349	19	7	553	5	508	5e-34	147
rs:WP_026648908	DNA topoisomerase III [Blautia wexlerae].	25.91	575	342	18	7	552	4	523	5e-34	147
rs:WP_012443177	DNA topoisomerase III [Erwinia tasmaniensis].	25.61	617	383	23	8	572	5	597	5e-34	147
rs:WP_015858922	DNA topoisomerase I [Thermococcus gammatolerans].	26.26	617	373	20	4	589	2	567	5e-34	147
rs:WP_012457618	DNA topoisomerase I [Porphyromonas gingivalis].	26.81	567	361	19	4	550	1	533	6e-34	147
rs:WP_025190821	DNA topoisomerase, partial [Enterococcus faecalis].	26.33	471	294	13	124	563	1	449	6e-34	145
rs:WP_027365964	hypothetical protein, partial [Desulfotomaculum alcoholivorax].	33.14	338	201	9	1	334	1	317	6e-34	141
rs:WP_028728974	DNA topoisomerase I, partial [Parabacteroides gordonii].	28.54	410	254	13	136	531	2	386	7e-34	142
rs:WP_019792391	hypothetical protein [Streptococcus sobrinus].	25.40	567	353	18	5	550	3	520	7e-34	145
rs:WP_046999514	hypothetical protein [Bifidobacterium adolescentis].	26.85	581	356	20	7	549	4	553	7e-34	147
rs:WP_017172407	hypothetical protein [Xanthomonas axonopodis].	27.26	576	362	21	7	550	6	556	7e-34	147
rs:WP_001895995	DNA topoisomerase III, partial [Vibrio cholerae].	32.94	252	157	6	297	539	1	249	7e-34	142
rs:WP_000520758	DNA topoisomerase I [Bacillus thuringiensis].	26.80	571	375	19	34	587	38	582	7e-34	147
rs:WP_000520734	DNA topoisomerase I [Bacillus cereus].	27.21	621	405	19	5	606	4	596	8e-34	147
sp:TOP1_ARCFU	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.69	567	356	18	7	566	7	509	8e-34	146
rs:WP_047192026	DNA topoisomerase [Microvirga vignae].	25.87	549	343	18	29	532	11	540	8e-34	147
tr:A0A075WFN2_ARCFL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.69	567	356	18	7	566	5	507	8e-34	146
tr:A0A091C1Y9_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.93	427	262	15	41	450	1	394	8e-34	143
rs:WP_044858971	DNA topoisomerase III, partial [Enterobacter cloacae].	32.25	276	173	7	298	563	1	272	8e-34	141
rs:WP_013293439	DNA topoisomerase [Gallionella capsiferriformans].	26.58	632	323	24	5	595	16	547	9e-34	145
tr:C7X9U5_9PORP	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEU51022.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EEU51022.1};	26.44	522	339	14	49	552	5	499	9e-34	146
rs:WP_029427001	DNA topoisomerase I [Bacteroides cellulosilyticus].	26.35	573	355	21	7	550	4	538	9e-34	146
rs:WP_021439520	DNA topoisomerase [Neisseria meningitidis].	27.24	569	332	20	3	532	2	527	9e-34	147
rs:WP_042512118	DNA topoisomerase I [Bacillus cereus].	26.23	629	401	17	5	606	4	596	1e-33	147
rs:WP_042827078	DNA topoisomerase [Xanthomonas axonopodis].	27.26	576	362	21	7	550	6	556	1e-33	147
rs:WP_017170432	hypothetical protein [Xanthomonas axonopodis].	27.26	576	362	21	7	550	6	556	1e-33	147
gpu:CP009928_113	DNA topoisomerase I [Chryseobacterium gallinarum]	26.49	570	355	18	7	550	4	535	1e-33	146
rs:WP_035725181	DNA topoisomerase III, partial [Gracilibacillus boraciitolerans].	32.24	335	199	12	3	333	2	312	1e-33	140
tr:D8HAD9_BACAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.15	582	365	18	48	606	34	579	1e-33	147
rs:WP_044782902	MULTISPECIES: DNA topoisomerase III [Bacillus cereus group].	25.77	617	395	24	7	603	6	579	1e-33	146
rs:WP_042700412	DNA topoisomerase I [Thermococcus sp. PK].	26.88	558	336	19	5	539	3	511	1e-33	146
rs:WP_017143085	DNA topoisomerase I [Bacteroides finegoldii].	28.28	442	276	14	122	550	2	415	1e-33	144
tr:A8SC99_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.21	452	281	12	111	547	17	435	1e-33	145
rs:WP_005965580	DNA topoisomerase [Fusobacterium periodonticum].	24.81	532	335	16	42	540	38	537	1e-33	146
rs:WP_014733804	DNA topoisomerase I [Pyrococcus sp. ST04].	26.08	625	358	25	7	589	4	566	2e-33	145
rs:WP_046831107	DNA topoisomerase III, partial [Xanthomonas axonopodis].	28.09	356	231	10	202	539	6	354	2e-33	142
rs:WP_046985670	DNA topoisomerase III, partial [Thermomonas brevis].	34.31	239	143	4	326	552	5	241	2e-33	141
tr:C7H3L1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.61	489	312	14	16	491	1	460	2e-33	143
rs:WP_031860929	DNA topoisomerase III, partial [Staphylococcus aureus].	30.37	438	274	14	5	431	3	420	2e-33	142
tr:A0A011QH80_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.87	562	340	19	7	527	6	537	2e-33	144
rs:WP_019226534	hypothetical protein [Dehalobacter sp. E1].	25.00	568	352	18	7	539	4	532	2e-33	145
rs:WP_036857289	DNA topoisomerase I [Prevotella denticola].	25.18	552	349	17	5	531	3	515	2e-33	145
rs:WP_009751280	DNA topoisomerase [Capnocytophaga sp. oral taxon 332].	25.70	642	400	19	5	603	4	611	2e-33	145
rs:WP_007749118	DNA topoisomerase I [Bacteroides finegoldii].	24.50	600	389	15	15	592	2	559	2e-33	145
rs:WP_016078683	DNA topoisomerase 1 [Bacillus cereus].	26.35	630	399	18	5	606	4	596	2e-33	146
tr:W4VNY9_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	32.24	335	199	12	3	333	2	312	2e-33	140
rs:WP_034951136	DNA topoisomerase III, partial [Erwinia oleae].	39.17	217	117	4	328	531	1	215	2e-33	140
tr:A0A097QU60_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.71	614	372	21	5	589	3	567	2e-33	145
rs:WP_002244206	DNA topoisomerase [Neisseria meningitidis].	26.46	567	339	17	3	532	2	527	2e-33	146
rs:WP_044423162	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	32.36	309	187	8	8	309	5	298	2e-33	139
rs:WP_027866354	hypothetical protein [Massilia alkalitolerans].	26.21	496	315	18	7	470	2	478	2e-33	143
rs:WP_012571272	DNA topoisomerase I [Thermococcus onnurineus].	26.99	615	371	22	4	589	2	567	2e-33	145
tr:X5NVB0_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.18	508	308	16	56	548	2	457	2e-33	144
rs:WP_042276999	hypothetical protein, partial [Burkholderia fungorum].	26.84	585	361	22	7	557	5	556	2e-33	144
tr:A0A075H2Q2_9EURY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.19	537	334	17	4	531	2	490	2e-33	145
rs:WP_038694802	DNA topoisomerase I [Sphingobacterium sp. ML3W].	26.16	558	353	19	7	539	4	527	2e-33	145
rs:WP_012966107	DNA topoisomerase I [Ferroglobus placidus].	26.22	572	338	24	7	566	4	503	2e-33	145
tr:R4NN51_CLOBO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.81	369	224	12	213	559	1	356	2e-33	143
rs:WP_016478637	DNA topoisomerase III [Capnocytophaga sp. oral taxon 336].	26.59	583	369	19	5	557	4	557	2e-33	145
tr:Z2EZT3_VIBPH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.06	316	200	9	155	459	25	330	2e-33	140
rs:WP_027829209	hypothetical protein [Lactobacillus harbinensis].	24.56	562	372	17	7	552	6	531	3e-33	145
rs:WP_020331515	DNA topoisomerase III [Vibrio fluvialis].	25.70	607	360	24	7	531	4	601	3e-33	146
rs:WP_045592690	hypothetical protein [Vibrio vulnificus].	25.45	605	364	23	7	531	4	601	3e-33	146
rs:WP_022358423	DNA topoisomerase [Clostridium sp. CAG:43].	27.35	468	272	17	7	417	6	462	3e-33	145
rs:WP_002349797	DNA topoisomerase, partial [Enterococcus faecium].	28.61	416	266	14	5	406	3	401	3e-33	141
rs:WP_009640589	DNA topoisomerase [Capnocytophaga sp. CM59].	25.12	641	400	20	5	603	4	606	3e-33	145
rs:WP_036613568	DNA topoisomerase III, partial [Oribacterium sp. P6A1].	28.00	425	254	14	7	419	6	390	3e-33	141
rs:WP_034948907	DNA topoisomerase III, partial [Erwinia oleae].	31.15	321	196	9	279	581	55	368	3e-33	142
rs:WP_035586006	hypothetical protein, partial [Eggerthella lenta].	24.65	564	355	20	5	532	3	532	3e-33	145
rs:WP_023842835	DNA topoisomerase [Burkholderia sp. M701].	27.26	609	365	21	5	561	4	586	3e-33	145
rs:WP_016121531	DNA topoisomerase 3, partial [Bacillus cereus].	31.25	336	203	11	5	336	4	315	3e-33	139
rs:WP_000280351	hypothetical protein [Bacillus cereus].	25.88	541	342	16	43	544	43	563	3e-33	145
rs:WP_009905893	DNA topoisomerase [Peptoclostridium difficile].	27.90	466	306	12	134	590	8	452	3e-33	144
rs:WP_010782941	DNA topoisomerase III, partial [Enterococcus faecalis].	30.25	433	277	12	120	544	2	417	3e-33	143
rs:WP_039784659	hypothetical protein, partial [Ancylobacter sp. FA202].	26.82	466	294	13	5	450	3	441	3e-33	141
rs:WP_013292672	DNA topoisomerase [Gallionella capsiferriformans].	27.22	562	285	20	5	539	16	480	3e-33	143
tr:C2UN45_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.88	541	342	16	43	544	39	559	3e-33	145
rs:WP_002678088	DNA topoisomerase [Capnocytophaga sputigena].	26.15	585	373	18	3	557	2	557	3e-33	145
rs:WP_044996218	DNA topoisomerase III [Lachnospiraceae bacterium JC7].	25.22	567	349	18	7	539	6	531	4e-33	144
tr:W6M0Y1_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.95	622	369	20	7	548	5	602	4e-33	146
rs:WP_029392519	DNA topoisomerase III, partial [Escherichia coli].	28.42	468	298	11	100	540	18	475	4e-33	144
tr:D4L9E3_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.08	469	288	11	102	550	4	438	4e-33	143
rs:WP_044456500	DNA topoisomerase, partial [Bacillus subtilis].	26.86	484	324	15	5	472	3	472	4e-33	142
rs:WP_036872634	DNA topoisomerase I [Porphyromonas macacae].	26.69	547	351	17	4	531	1	516	4e-33	144
rs:WP_044423544	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	32.11	246	153	5	285	517	1	245	5e-33	137
rs:WP_002643085	DNA topoisomerase III [Simonsiella muelleri].	25.00	564	350	17	3	532	2	526	5e-33	144
tr:A0A096LKN5_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	24.65	564	355	20	5	532	3	532	5e-33	144
tr:K5DE93_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKJ91283.1};	28.18	440	275	14	124	550	1	412	5e-33	143
rs:WP_032548386	DNA topoisomerase, partial [Peptoclostridium difficile].	27.22	485	329	14	72	544	3	475	5e-33	143
rs:WP_033874207	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	33.47	248	146	6	8	251	5	237	5e-33	136
tr:A0A0A7GF84_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.52	558	342	20	7	553	4	504	5e-33	144
rs:WP_044798599	DNA topoisomerase I [Bacillus thuringiensis].	27.50	571	372	20	34	587	38	583	5e-33	145
rs:WP_003526249	hypothetical protein, partial [[Clostridium] clostridioforme].	27.58	388	242	11	7	389	4	357	5e-33	139
tr:A0A090T775_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.46	383	231	12	155	513	8	371	5e-33	140
rs:WP_046420451	DNA topoisomerase, partial [Xylella fastidiosa].	31.77	299	174	9	254	530	16	306	5e-33	141
rs:WP_015590146	DNA topoisomerase I [Archaeoglobus sulfaticallidus].	24.87	559	363	15	1	553	1	508	6e-33	144
rs:WP_009270778	DNA topoisomerase III [Erysipelotrichaceae bacterium 21_3].	25.99	558	355	15	3	539	2	522	6e-33	144
tr:G6C564_9FUSO	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHI77883.1};	24.20	533	338	15	42	540	52	552	6e-33	144
tr:F8K840_STRPY	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.27	554	335	18	7	539	42	537	6e-33	143
rs:WP_039698954	hypothetical protein [Clostridium botulinum].	26.96	549	345	21	7	533	5	519	6e-33	144
rs:WP_035495790	DNA topoisomerase [Fusobacterium sp. oral taxon 370].	24.20	533	338	15	42	540	38	538	6e-33	144
rs:WP_007754045	DNA topoisomerase I [Bacteroides finegoldii].	26.87	547	344	20	15	539	2	514	7e-33	144
rs:WP_007716460	DNA topoisomerase III [[Clostridium] asparagiforme].	25.43	578	346	21	7	548	4	532	7e-33	144
rs:WP_000280354	hypothetical protein [Bacillus cereus].	25.32	541	345	15	43	544	43	563	7e-33	144
rs:WP_038167017	DNA topoisomerase III, partial [Vibrio shilonii].	31.08	399	234	13	162	532	6	391	8e-33	142
rs:WP_032517984	DNA topoisomerase, partial [Peptoclostridium difficile].	27.22	485	329	14	72	544	3	475	8e-33	143
rs:WP_002318450	DNA topoisomerase, partial [Enterococcus faecium].	28.68	408	250	12	166	556	11	394	8e-33	142
rs:WP_044193063	DNA topoisomerase I, partial [Parabacteroides gordonii].	28.81	413	249	14	136	531	2	386	8e-33	139
rs:WP_000165792	DNA topoisomerase III [Bacillus cereus].	28.07	431	281	10	135	544	6	428	8e-33	144
rs:WP_004318971	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.57	571	368	19	4	550	1	538	8e-33	144
rs:WP_033496031	DNA topoisomerase III [Bifidobacterium biavatii].	26.15	608	365	21	7	566	4	575	8e-33	144
rs:WP_016682821	DNA topoisomerase III, partial [Yersinia pestis].	29.40	398	261	9	67	453	3	391	9e-33	140
tr:V2NIF4_SALET	SubName: Full=Topoisomerase {ECO:0000313|EMBL:ESJ74434.1};	25.84	507	323	14	107	574	31	523	1e-32	143
tr:A0A0B5HW63_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.42	549	313	21	7	531	6	498	1e-32	144
rs:WP_008389044	DNA topoisomerase I [Halosarcina pallida].	24.77	541	351	17	7	532	8	507	1e-32	144
rs:WP_013293892	DNA topoisomerase [Gallionella capsiferriformans].	26.66	604	305	22	5	567	16	522	1e-32	142
tr:U5JDV2_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.01	485	330	14	72	544	1	473	1e-32	142
rs:WP_034217778	DNA topoisomerase III, partial [Lachnospiraceae bacterium AB2028].	26.18	550	348	18	7	539	11	519	1e-32	142
rs:WP_016296807	hypothetical protein [Lachnospiraceae bacterium M18-1].	23.81	609	367	20	8	534	7	600	1e-32	143
rs:WP_032133432	DNA topoisomerase III [Kingella kingae].	27.53	563	337	17	3	532	2	526	1e-32	143
rs:WP_033624195	DNA topoisomerase, partial [Enterococcus faecium].	27.82	435	289	14	5	428	3	423	1e-32	140
rs:WP_036421357	DNA topoisomerase III, partial [Morganella morganii].	27.97	472	298	17	7	459	4	452	1e-32	140
rs:WP_047021715	topoisomerase I, partial [Lactobacillus brevis].	29.37	412	250	13	174	563	4	396	1e-32	141
tr:S4EDR9_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.60	402	262	11	174	563	3	395	1e-32	141
rs:WP_020736077	ATP-dependent DNA helicase RecQ [Sorangium cellulosum].	24.39	615	357	18	4	531	1	594	1e-32	144
rs:WP_043544899	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	34.43	244	141	5	326	552	6	247	1e-32	138
rs:WP_043459152	hypothetical protein, partial [Azohydromonas australica].	27.74	465	267	18	135	557	8	445	1e-32	142
rs:WP_033389182	topoisomerase I, partial [Lactobacillus parabrevis].	27.62	449	284	14	174	603	4	430	1e-32	141
rs:WP_029739023	DNA topoisomerase, partial [Enterococcus faecalis].	27.66	441	294	13	5	434	3	429	1e-32	139
tr:C2XKX2_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.63	627	401	20	5	606	11	603	1e-32	144
tr:L2JM52_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.60	402	262	11	174	563	3	395	1e-32	141
tr:C3DEJ5_BACTS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.31	294	161	9	280	548	1	281	2e-32	140
rs:WP_009411156	DNA topoisomerase [Capnocytophaga sp. oral taxon 324].	25.81	585	373	18	5	557	3	558	2e-32	143
rs:WP_040220752	DNA topoisomerase III, partial [Klebsiella pneumoniae].	28.07	456	286	15	38	469	8	445	2e-32	140
rs:WP_040221470	DNA topoisomerase [Collinsella sp. MS5].	25.33	537	342	16	65	587	109	600	2e-32	143
rs:WP_047184914	DNA topoisomerase III, partial [Bacilli bacterium VT-13-104].	30.75	348	209	11	3	344	2	323	2e-32	138
tr:C2BCN7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.64	426	238	15	145	551	4	382	2e-32	139
tr:A0A073ICB2_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KEJ87404.1};	29.13	381	230	13	166	531	28	383	2e-32	141
rs:WP_034284084	DNA topoisomerase, partial [Aeromonas salmonicida].	31.35	303	190	6	251	539	11	309	2e-32	139
rs:WP_021630736	DNA topoisomerase [Clostridium sp. ATCC BAA-442].	26.09	552	356	16	7	548	5	514	2e-32	142
rs:WP_044444103	DNA topoisomerase I [Bacillus mycoides].	27.91	473	287	11	5	451	4	448	2e-32	143
rs:WP_019789876	hypothetical protein [Streptococcus sobrinus].	25.04	567	355	18	5	550	3	520	2e-32	141
tr:E0H2D5_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.66	441	294	13	5	434	3	429	2e-32	139
rs:WP_042226552	DNA topoisomerase III [Kingella kingae].	25.00	564	347	17	5	532	4	527	2e-32	142
rs:WP_034949874	DNA topoisomerase III, partial [Erwinia oleae].	32.16	255	163	3	8	262	5	249	2e-32	135
tr:F2ZR02_9PSED	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGI04855.1}; Flags: Fragment;	32.70	263	158	6	8	266	5	252	2e-32	135
rs:WP_038303891	DNA topoisomerase III [Kingella kingae].	24.96	561	351	16	5	532	4	527	2e-32	142
rs:WP_026648650	DNA topoisomerase III [Blautia wexlerae].	25.13	557	348	18	7	539	4	515	2e-32	142
rs:WP_022386816	hypothetical protein [Collinsella sp. CAG:289].	25.33	537	342	16	65	587	109	600	2e-32	143
rs:WP_000165791	DNA topoisomerase III [Bacillus thuringiensis].	28.07	431	281	10	135	544	6	428	2e-32	142
rs:WP_005962827	DNA topoisomerase III [Fusobacterium necrophorum].	28.94	387	238	10	7	389	4	357	2e-32	140
tr:K1U494_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC73180.1}; Flags: Fragment;	29.87	385	227	13	7	384	17	365	2e-32	138
rs:WP_035478371	hypothetical protein, partial [Burkholderia phenoliruptrix].	26.33	581	369	21	7	557	5	556	2e-32	141
rs:XP_004334075	DNA topoisomerase [Acanthamoeba castellanii str. Neff].	25.59	719	383	29	4	597	239	930	2e-32	143
rs:WP_038309401	DNA topoisomerase III [Kingella kingae].	25.00	564	347	17	5	532	4	527	2e-32	142
rs:WP_033872209	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	33.88	242	141	6	8	245	5	231	2e-32	134
rs:WP_008824364	hypothetical protein, partial [Prevotella histicola].	25.71	459	296	13	4	452	2	425	2e-32	139
rs:WP_000520731	DNA topoisomerase I [Bacillus cereus].	26.63	627	401	20	5	606	4	596	2e-32	143
rs:WP_034706710	DNA topoisomerase, partial [Enterococcus gallinarum].	27.82	435	289	14	5	428	3	423	2e-32	139
rs:WP_046148757	DNA topoisomerase I [Parabacteroides sp. HGS0025].	25.13	577	363	20	4	550	1	538	3e-32	142
rs:WP_021485677	DNA topoisomerase III [Vibrio parahaemolyticus].	24.88	607	367	23	7	532	4	602	3e-32	143
sp:TOP1_PYRAB	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.72	623	369	22	7	589	4	566	3e-32	142
rs:WP_039064406	DNA topoisomerase III, partial [Shigella boydii].	28.42	461	297	12	112	548	39	490	3e-32	142
rs:WP_005794014	DNA topoisomerase I [Bacteroides fragilis].	25.52	572	367	22	4	550	1	538	3e-32	142
rs:WP_013683176	DNA topoisomerase I [Archaeoglobus veneficus].	26.04	553	347	19	7	550	5	504	3e-32	141
rs:WP_044561089	hypothetical protein [Azospirillum sp. B4].	25.91	548	351	18	40	544	49	584	3e-32	142
rs:WP_012194426	DNA topoisomerase I [Methanococcus maripaludis].	28.62	545	329	24	7	539	5	501	3e-32	142
tr:A0A090QXC2_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.65	370	245	9	8	368	6	365	3e-32	137
tr:K1TSU6_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC76072.1}; Flags: Fragment;	27.48	393	244	9	110	486	12	379	3e-32	139
rs:WP_031604130	DNA topoisomerase III, partial [Salmonella enterica].	31.97	244	156	5	315	552	2	241	3e-32	136
tr:R8UL10_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.19	418	236	15	170	550	10	404	3e-32	141
tr:V2LUX5_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	28.02	364	242	10	8	361	5	358	4e-32	137
rs:WP_040466192	DNA topoisomerase III, partial [Holdemanella biformis].	25.20	508	322	16	7	491	4	476	4e-32	139
rs:WP_000280355	DNA topoisomerase III [Bacillus thuringiensis].	25.19	540	347	15	43	544	43	563	4e-32	142
tr:F9Y0V9_BIFBU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.29	502	279	18	100	549	2	469	4e-32	141
rs:WP_041473510	hypothetical protein, partial [Bifidobacterium breve].	27.29	502	279	18	100	549	15	482	4e-32	141
tr:B7C9A6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.20	508	322	16	7	491	4	476	4e-32	139
rs:WP_042932891	DNA topoisomerase III, partial [Pseudomonas coronafaciens].	33.33	255	151	6	8	258	5	244	4e-32	134
rs:WP_042101431	DNA topoisomerase III, partial [Escherichia coli].	31.47	251	162	5	308	552	1	247	4e-32	136
rs:WP_000280352	hypothetical protein [Bacillus cereus].	25.00	540	348	15	43	544	43	563	4e-32	142
rs:WP_029491379	DNA topoisomerase [Fusobacterium hwasookii].	23.62	580	370	17	42	584	38	581	4e-32	141
rs:WP_036888889	DNA topoisomerase I, partial [Porphyromonas crevioricanis].	26.50	517	312	19	4	485	1	484	5e-32	139
rs:WP_035458144	hypothetical protein, partial [Bacteroides uniformis].	28.34	434	264	15	136	552	3	406	5e-32	140
rs:WP_021670479	DNA topoisomerase, partial [Prevotella sp. F0091].	26.98	441	275	11	107	531	47	456	5e-32	140
tr:R9HPA4_BACUN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS05606.1};	28.34	434	264	15	136	552	2	405	5e-32	140
rs:WP_037305170	hypothetical protein [Ruminococcus albus].	28.03	528	330	15	22	540	1	487	5e-32	141
rs:WP_044133343	DNA topoisomerase III, partial [Bacteroides fragilis].	27.01	422	272	12	7	408	2	407	5e-32	137
rs:WP_002349703	DNA topoisomerase, partial [Enterococcus faecium].	28.22	411	267	10	170	563	29	428	5e-32	139
tr:E6UKV8_RUMA7	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.72	534	336	15	16	540	1	493	5e-32	141
tr:A6G6C2_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.99	581	360	17	7	539	5	563	6e-32	142
tr:U5SB31_9LACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.15	388	241	12	6	385	7	372	6e-32	137
rs:WP_002561265	DNA topoisomerase III [Bacteroides sp. HPS0048].	24.96	577	364	20	4	550	1	538	6e-32	141
rs:WP_009432418	DNA topoisomerase, partial [Porphyromonas sp. oral taxon 279].	25.89	448	287	12	107	539	8	425	6e-32	140
rs:WP_032329999	DNA topoisomerase III, partial [Escherichia coli].	28.24	393	263	11	7	391	4	385	6e-32	137
rs:WP_043945782	DNA topoisomerase III, partial [Carnobacterium sp. WN1359].	30.15	388	241	12	6	385	4	369	6e-32	137
rs:WP_045719108	DNA topoisomerase III, partial [Salmonella enterica].	31.97	244	156	5	315	552	1	240	6e-32	136
rs:WP_045116179	hypothetical protein [Plesiocystis pacifica].	25.90	583	362	17	5	539	11	571	6e-32	142
rs:WP_031910263	DNA topoisomerase III, partial [Staphylococcus aureus].	28.49	372	236	12	201	559	15	369	7e-32	138
rs:WP_019780742	hypothetical protein, partial [Streptococcus sobrinus].	25.82	519	322	16	48	550	23	494	7e-32	139
rs:WP_000280353	DNA topoisomerase III [Bacillus cereus].	24.60	569	361	16	43	563	43	591	7e-32	141
tr:A0A031KIR6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.75	400	223	13	110	491	1	356	7e-32	136
rs:WP_001235772	MULTISPECIES: DNA topoisomerase III [Enterobacteriaceae].	28.24	393	263	11	7	391	4	385	7e-32	137
rs:WP_041326775	DNA topoisomerase III, partial [Ruminococcus champanellensis].	25.54	462	296	14	7	458	5	428	7e-32	137
rs:WP_015791283	DNA topoisomerase I [Methanocaldococcus fervens].	29.41	578	335	23	7	567	5	526	8e-32	141
rs:WP_033607002	hypothetical protein, partial [Enterococcus faecium].	26.84	421	286	9	135	544	4	413	8e-32	139
rs:WP_024720786	DNA topoisomerase III [Clostridiales bacterium VE202-01].	26.13	509	309	15	7	491	4	469	8e-32	138
rs:WP_023625372	hypothetical protein, partial [Clostridium tyrobutyricum].	27.91	455	286	15	7	448	4	429	8e-32	137
tr:D7INW6_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFI09104.1};	25.68	584	351	20	4	550	1	538	8e-32	140
rs:WP_033644788	DNA topoisomerase, partial [Enterococcus faecium].	28.75	400	223	13	110	491	1	356	8e-32	136
rs:WP_005644270	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	25.68	584	351	20	4	550	24	561	9e-32	140
rs:WP_001545303	DNA topoisomerase, partial [Escherichia coli].	30.19	265	175	3	8	272	5	259	9e-32	134
tr:C2TQW3_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	24.77	541	348	14	43	544	39	559	9e-32	140
rs:WP_000280356	hypothetical protein [Bacillus cereus].	24.77	541	348	14	43	544	43	563	9e-32	140
rs:WP_033693711	DNA topoisomerase III [Bacillus cereus].	24.77	541	348	14	43	544	43	563	9e-32	140
rs:WP_027181485	DNA topoisomerase III [Desulfovibrio alaskensis].	30.13	375	237	12	242	603	292	654	9e-32	141
rs:WP_027181485	DNA topoisomerase III [Desulfovibrio alaskensis].	25.21	238	160	5	1	236	1	222	8e-12	78.6
rs:WP_001235771	hypothetical protein, partial [Salmonella enterica].	28.24	393	263	11	7	391	4	385	9e-32	136
tr:F5X1Y0_STRPX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.05	527	344	17	41	557	5	490	9e-32	139
rs:WP_032072231	DNA topoisomerase III [Escherichia coli].	28.24	393	263	11	7	391	4	385	9e-32	137
rs:WP_022775098	hypothetical protein [Butyrivibrio sp. AE2015].	27.08	613	369	26	1	579	1	569	1e-31	140
rs:WP_042631280	DNA topoisomerase III [Bacillus cereus].	24.77	541	348	14	43	544	43	563	1e-31	140
rs:WP_011367300	DNA topoisomerase III [Desulfovibrio alaskensis].	30.13	375	237	12	242	603	292	654	1e-31	140
rs:WP_011367300	DNA topoisomerase III [Desulfovibrio alaskensis].	25.21	238	160	5	1	236	1	222	1e-11	78.2
tr:D4LEK1_RUMC1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.54	462	296	14	7	458	5	428	1e-31	137
rs:WP_031613730	DNA topoisomerase III, partial [Salmonella enterica].	31.97	244	156	5	315	552	4	243	1e-31	135
rs:WP_031942367	DNA topoisomerase III [Escherichia coli].	27.70	473	302	10	100	544	21	481	1e-31	139
tr:A0A0D5V227_9BURK	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:AJZ56126.1};	27.21	566	350	21	7	543	5	537	1e-31	140
rs:WP_039931121	hypothetical protein, partial [Anaerococcus lactolyticus].	25.41	547	350	20	7	539	4	506	1e-31	139
rs:WP_033017353	DNA topoisomerase III, partial [Geobacillus stearothermophilus].	27.15	372	249	9	94	456	17	375	1e-31	136
rs:WP_033858676	DNA topoisomerase III, partial [Staphylococcus aureus].	28.49	372	236	12	201	559	13	367	2e-31	138
rs:WP_031921622	DNA topoisomerase III, partial [Staphylococcus aureus].	28.65	370	234	12	203	559	1	353	2e-31	138
rs:WP_010206361	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	29.90	301	195	6	220	505	2	301	2e-31	134
rs:WP_031786141	DNA topoisomerase III, partial [Staphylococcus aureus].	28.49	372	236	12	201	559	14	368	2e-31	138
rs:WP_031923560	DNA topoisomerase III, partial [Staphylococcus aureus].	30.99	413	254	14	5	406	3	395	2e-31	136
tr:A0A0A2V3B3_BEABA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.36	436	260	15	5	414	4	417	2e-31	136
rs:WP_012289980	DNA topoisomerase III [Finegoldia magna].	27.32	571	347	21	43	596	36	555	2e-31	139
gpu:CP011267_459	DNA topoisomerase I [Geoglobus ahangari]	24.68	555	356	17	7	553	4	504	2e-31	139
rs:WP_018153854	DNA topoisomerase I [Methanothermococcus thermolithotrophicus].	27.64	550	330	22	7	539	5	503	2e-31	140
rs:WP_036681478	hypothetical protein [Paenibacillus sp. FSL H8-237].	26.15	566	363	18	7	544	6	544	2e-31	140
rs:WP_031620761	DNA topoisomerase III, partial [Salmonella enterica].	31.67	240	154	5	319	552	1	236	2e-31	133
rs:WP_013466927	DNA topoisomerase I [Thermococcus barophilus].	25.67	561	341	18	4	539	2	511	2e-31	139
tr:E1KTZ0_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFL45038.1};	26.26	514	316	18	7	495	5	480	2e-31	137
rs:WP_032133874	DNA topoisomerase III [Kingella kingae].	25.09	566	348	17	3	532	2	527	2e-31	139
rs:WP_005552553	DNA topoisomerase 3 [Paenibacillus alvei].	26.48	574	373	16	4	544	1	558	2e-31	140
rs:WP_044798418	DNA topoisomerase I [Bacillus thuringiensis].	26.23	629	401	19	5	606	4	596	2e-31	140
tr:T1ZVG8_STRAP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AGU81557.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AGU81557.1};	25.51	494	322	13	67	550	7	464	2e-31	137
rs:WP_009276709	MULTISPECIES: DNA topoisomerase I [Parabacteroides].	25.68	584	351	20	4	550	24	561	2e-31	139
rs:WP_008084733	DNA topoisomerase I [Aciduliprofundum boonei].	25.58	559	349	21	7	553	5	508	3e-31	139
rs:WP_021938600	DNA topoisomerase [Coprococcus sp. CAG:782].	28.29	410	253	12	177	550	1	405	3e-31	137
rs:WP_000165790	DNA topoisomerase III [Bacillus thuringiensis].	27.67	430	284	9	135	544	6	428	3e-31	139
rs:WP_008009864	DNA topoisomerase I [Haloterrigena limicola].	23.72	607	394	20	7	589	4	565	3e-31	139
rs:WP_026745683	DNA topoisomerase III [Leptotrichia hofstadii].	28.39	560	344	21	7	548	5	525	3e-31	139
rs:WP_044356048	DNA topoisomerase III, partial [Paenibacillus sp. E194].	29.71	340	209	10	7	341	5	319	3e-31	134
rs:WP_034292903	DNA topoisomerase III [Alysiella crassa].	25.18	564	349	17	3	532	2	526	3e-31	139
rs:WP_031904996	DNA topoisomerase III, partial [Staphylococcus aureus].	31.31	396	241	14	5	389	3	378	3e-31	135
rs:WP_042080259	DNA topoisomerase III, partial [Escherichia coli].	31.97	244	156	5	315	552	1	240	4e-31	134
rs:WP_040187426	DNA topoisomerase III, partial [Halomonas salina].	27.90	319	217	8	7	322	4	312	4e-31	133
tr:A0A078RFF4_BACVU	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:KDS33481.1};	25.45	558	361	16	16	550	1	526	4e-31	139
rs:WP_043553820	DNA topoisomerase I, partial [Acetobacter malorum].	27.10	465	296	13	91	536	59	499	4e-31	137
tr:C2BD67_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.41	547	350	20	7	539	8	510	4e-31	138
rs:WP_021738983	DNA topoisomerase, partial [Eubacterium ramulus].	27.82	417	262	14	17	427	1	384	4e-31	134
rs:WP_044803320	DNA topoisomerase III, partial [Bacillus amyloliquefaciens].	35.14	276	151	11	292	548	2	268	4e-31	135
rs:WP_039585037	DNA topoisomerase III, partial [Xanthomonas axonopodis].	30.22	278	173	8	280	539	11	285	4e-31	133
rs:WP_010601443	DNA topoisomerase type IA central domain-containing protein, partial [Pedobacter agri].	29.17	408	244	15	156	543	2	384	5e-31	135
rs:WP_013194169	DNA topoisomerase I [Methanohalobium evestigatum].	25.73	548	346	18	7	539	4	505	5e-31	139
rs:WP_001840255	DNA topoisomerase III, partial [Salmonella enterica].	28.95	342	223	10	8	339	5	336	5e-31	133
tr:A0A0E2SWY0_BACFG	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXZ78927.1};	25.25	503	331	13	56	539	2	478	5e-31	138
rs:WP_039575838	DNA topoisomerase III, partial [Xanthomonas axonopodis].	30.22	278	173	8	280	539	15	289	5e-31	133
tr:V1URM1_SALET	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESG40303.1};	34.31	204	127	2	343	539	1	204	5e-31	132
rs:WP_040227468	hypothetical protein [Bhargavaea cecembensis].	34.50	258	151	10	286	530	6	258	5e-31	135
rs:WP_008084369	DNA topoisomerase I [Aciduliprofundum boonei].	25.40	559	350	21	7	553	5	508	5e-31	138
rs:WP_036295630	DNA topoisomerase, partial [Methylobacter whittenburyi].	31.07	280	153	6	279	548	9	258	6e-31	131
rs:WP_041019761	DNA topoisomerase III, partial [Xanthomonas axonopodis].	30.22	278	173	8	280	539	17	291	6e-31	133
rs:WP_010902213	DNA topoisomerase I [Halobacterium salinarum].	24.08	544	365	15	7	539	4	510	6e-31	138
tr:A0A087PJ20_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.10	465	296	13	91	536	59	499	7e-31	137
rs:WP_042832016	DNA topoisomerase III, partial [Xanthomonas citri].	32.91	234	151	4	200	428	15	247	7e-31	131
rs:WP_022348616	hypothetical protein [Collinsella sp. CAG:398].	25.60	543	336	17	65	587	108	602	7e-31	138
rs:WP_025790182	DNA topoisomerase I, partial [Prevotella loescheii].	25.97	462	291	13	4	452	2	425	7e-31	134
tr:F7LSI8_9BACE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN05987.1};	26.10	433	282	13	7	418	2	417	7e-31	134
rs:WP_040078239	DNA topoisomerase III, partial [Escherichia coli].	34.13	252	142	7	315	549	10	254	8e-31	134
rs:WP_000165793	hypothetical protein [Bacillus cereus].	27.48	433	281	11	135	544	6	428	8e-31	137
rs:WP_008645707	hypothetical protein, partial [Bacteroides sp. 1_1_30].	26.88	506	315	17	4	485	1	475	9e-31	135
rs:WP_019128852	DNA topoisomerase [Enorma massiliensis].	25.60	543	336	17	65	587	108	602	9e-31	138
rs:WP_021632670	DNA topoisomerase, partial [Clostridium sp. ATCC BAA-442].	30.27	337	200	12	291	601	2	329	9e-31	135
rs:WP_046735973	DNA topoisomerase III, partial [Xanthomonas axonopodis].	27.83	345	224	10	213	539	2	339	9e-31	134
rs:WP_005798105	DNA topoisomerase I [Bacteroides fragilis].	25.74	470	283	14	97	544	42	467	9e-31	137
rs:WP_012514069	DNA topoisomerase III [Hydrogenobaculum sp. Y04AAS1].	29.16	463	256	21	7	423	5	441	1e-30	137
tr:L9TE08_SALEN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	31.67	240	154	5	319	552	1	236	1e-30	132
rs:WP_033426509	hypothetical protein, partial [Salinicoccus albus].	28.57	420	275	9	135	544	5	409	1e-30	136
rs:WP_008777471	DNA topoisomerase I [Bacteroides sp. 2_2_4].	25.44	570	370	18	4	550	1	538	1e-30	137
rs:WP_036856688	DNA topoisomerase I, partial [Prevotella amnii].	25.36	489	306	15	5	469	3	456	1e-30	134
sp:TOP1_METJA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	27.79	583	352	22	1	567	1	530	1e-30	137
tr:B8IEL1_METNO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.05	547	349	17	29	532	20	548	1e-30	137
rs:WP_043751848	DNA topoisomerase [Methylobacterium nodulans].	25.05	547	349	17	29	532	11	539	1e-30	137
rs:WP_046720325	DNA topoisomerase III, partial [Pseudomonas syringae].	32.94	255	150	7	8	258	5	242	1e-30	130
rs:WP_009244366	DNA topoisomerase III [Lachnospiraceae bacterium 2_1_58FAA].	26.07	514	314	16	69	534	1	496	1e-30	136
rs:WP_020221956	DNA topoisomerase I [Halarchaeum acidiphilum].	24.18	550	357	18	7	539	4	510	1e-30	137
rs:WP_004032475	MULTISPECIES: DNA topoisomerase I [Methanobrevibacter].	27.65	557	329	23	7	543	5	507	2e-30	137
rs:WP_008800967	DNA topoisomerase III [Fusobacterium gonidiaformans].	25.47	585	367	22	4	557	1	547	2e-30	137
rs:WP_002366151	DNA topoisomerase, partial [Enterococcus faecium].	28.64	419	265	12	165	563	24	428	2e-30	135
rs:WP_004409943	DNA topoisomerase [Bacillus thuringiensis].	26.43	367	233	11	4	354	1	346	2e-30	132
rs:WP_004310027	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.44	570	370	18	4	550	1	538	2e-30	136
rs:WP_005680447	DNA topoisomerase I [Bacteroides caccae].	25.44	570	370	18	4	550	1	538	2e-30	136
rs:WP_012035064	DNA topoisomerase I [Methanocella arvoryzae].	26.00	550	334	20	7	539	4	497	2e-30	137
rs:WP_044798480	DNA topoisomerase I, partial [Bacillus thuringiensis].	25.87	630	402	19	5	606	4	596	2e-30	137
rs:WP_015419613	MULTISPECIES: DNA topoisomerase III [Hydrogenobaculum].	26.27	628	328	23	7	550	5	581	2e-30	137
rs:WP_042120515	DNA topoisomerase I, partial [Porphyromonas crevioricanis].	26.50	517	312	19	4	485	1	484	2e-30	134
rs:WP_031894067	DNA topoisomerase III, partial [Staphylococcus aureus].	30.25	400	256	11	151	544	1	383	2e-30	134
rs:WP_011954063	DNA topoisomerase I [Methanobrevibacter smithii].	27.65	557	329	22	7	543	5	507	2e-30	136
rs:WP_023039571	hypothetical protein [Fusobacterium nucleatum].	24.63	536	332	15	42	540	38	538	2e-30	136
rs:WP_017144917	DNA topoisomerase [Fusobacterium nucleatum].	24.63	536	332	15	42	540	38	538	2e-30	136
rs:WP_032136827	DNA topoisomerase [Kingella sp. Sch538].	25.92	571	338	20	3	532	2	528	2e-30	137
rs:WP_031271200	DNA topoisomerase III, partial [Lachnospiraceae bacterium 10-1].	26.17	447	285	12	110	539	1	419	2e-30	135
rs:WP_042680133	DNA topoisomerase I [Thermococcus sp. ES1].	25.36	556	349	18	4	539	2	511	2e-30	136
rs:WP_034530141	DNA topoisomerase I [Parabacteroides sp. 20_3].	25.17	584	354	20	4	550	24	561	2e-30	136
rs:WP_008645712	hypothetical protein, partial [Bacteroides sp. 1_1_30].	24.60	504	329	12	4	485	1	475	2e-30	134
rs:WP_010890147	hypothetical protein [Enterobacter aerogenes].	25.04	579	337	19	7	530	4	540	2e-30	136
tr:A0A0B5HKC5_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.43	582	363	21	4	567	2	530	3e-30	136
rs:WP_002887270	topoisomerase IA [Streptococcus salivarius].	25.18	560	344	23	41	546	37	575	3e-30	136
tr:E1YNZ2_9PORP	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFK64041.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFK64041.1};	25.17	584	354	20	4	550	1	538	3e-30	136
rs:WP_032576687	DNA topoisomerase I [Bacteroides fragilis].	25.74	571	367	19	4	550	1	538	3e-30	136
rs:WP_007838676	DNA topoisomerase I [Bacteroides dorei].	25.61	574	358	18	7	550	4	538	3e-30	136
tr:A0A0B3AKA5_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.87	545	332	18	7	539	135	619	3e-30	136
rs:WP_007044609	DNA topoisomerase I [Methanotorris formicicus].	28.72	578	344	24	4	567	2	525	3e-30	136
rs:WP_031860277	DNA topoisomerase III, partial [Staphylococcus aureus].	31.36	287	179	9	285	559	20	300	3e-30	131
rs:WP_019239215	DNA topoisomerase [Collinsella sp. GD3].	25.58	516	321	15	65	563	108	577	3e-30	136
tr:A0A0B3A8L9_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.16	567	344	19	7	565	128	633	3e-30	136
rs:WP_008656087	DNA topoisomerase I [Bacteroides sp. 3_1_33FAA].	27.35	457	268	16	97	536	42	451	3e-30	135
rs:WP_044067990	DNA topoisomerase III, partial [Escherichia coli].	31.56	244	157	5	315	552	5	244	3e-30	131
rs:WP_024599854	hypothetical protein [Pseudoalteromonas haloplanktis].	30.54	334	212	9	8	331	5	328	3e-30	131
tr:W7C7N0_LISGR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.11	338	222	8	277	603	1	328	4e-30	133
rs:WP_033609362	topoisomerase I, partial [Lactobacillus plantarum].	30.20	351	208	11	5	339	3	332	4e-30	131
rs:WP_033518198	DNA topoisomerase III, partial [Bifidobacterium cuniculi].	24.22	545	346	16	40	548	34	547	4e-30	135
tr:G9QFT9_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.19	415	253	13	166	556	4	397	4e-30	134
tr:A0A087AVV4_9BIFI	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KFI62904.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KFI62904.1};	24.22	545	346	16	40	548	34	547	4e-30	135
tr:A0A062V8Y9_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.60	496	319	14	48	539	47	496	4e-30	135
rs:WP_039893601	DNA topoisomerase, partial [Methylobacterium mesophilicum].	24.87	567	362	17	25	546	6	553	4e-30	135
rs:WP_012333944	DNA topoisomerase [Methylobacterium sp. 4-46].	24.01	554	360	15	29	539	11	546	4e-30	135
tr:B7IYV7_BACC2	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.57	428	277	11	140	544	4	421	4e-30	135
rs:WP_005898479	DNA topoisomerase [Fusobacterium nucleatum].	23.83	533	340	15	42	540	38	538	5e-30	135
rs:WP_011976610	DNA topoisomerase I [Methanococcus maripaludis].	27.42	547	333	23	7	539	5	501	5e-30	135
rs:WP_011868545	DNA topoisomerase I [Methanococcus maripaludis].	27.66	546	333	23	7	539	5	501	5e-30	135
tr:A0A0C6FJ59_9RHIZ	SubName: Full=TopA protein {ECO:0000313|EMBL:BAQ48568.1};	24.78	561	355	17	29	544	30	568	5e-30	135
rs:WP_008153388	hypothetical protein, partial [Parabacteroides johnsonii].	26.10	433	287	12	167	591	2	409	5e-30	133
tr:W4PNB6_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	26.65	514	329	16	56	550	2	486	5e-30	135
rs:WP_018261492	DNA topoisomerase [Methylobacterium sp. WSM2598].	23.83	554	361	15	29	539	11	546	6e-30	135
rs:WP_021885775	DNA topoisomerase [Clostridium sp. CAG:590].	28.22	443	275	14	107	539	9	418	6e-30	134
tr:H1HC00_FUSNU	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EHO79969.1}; Flags: Fragment;	25.00	468	297	10	103	540	30	473	6e-30	134
rs:WP_044132082	DNA topoisomerase I [Bacteroides fragilis].	25.26	570	371	18	4	550	1	538	7e-30	135
tr:A5ZNQ6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.82	548	346	16	81	603	5	511	7e-30	134
rs:WP_041909636	hypothetical protein, partial [Candidatus Iainarchaeum andersonii].	24.84	612	384	18	7	593	4	564	7e-30	134
rs:WP_011972751	DNA topoisomerase I [Methanococcus aeolicus].	27.14	549	341	22	7	539	5	510	7e-30	135
rs:WP_031883559	DNA topoisomerase III, partial [Staphylococcus aureus].	28.61	360	227	12	213	559	1	343	7e-30	132
rs:WP_005039100	DNA topoisomerase I [Halococcus salifodinae].	24.95	553	348	21	7	539	4	509	8e-30	135
tr:M7XYJ7_9RHIZ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.96	557	354	17	35	546	7	544	8e-30	135
rs:WP_041315236	hypothetical protein, partial [Heliobacterium modesticaldum].	25.42	590	371	20	5	550	3	567	8e-30	135
rs:WP_004367624	DNA topoisomerase TopB, partial [Prevotella nigrescens].	27.91	430	263	14	118	531	1	399	9e-30	133
tr:W4LYF2_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.05	358	225	9	5	357	3	336	9e-30	130
rs:WP_032882988	DNA topoisomerase, partial [Fusobacterium nucleatum].	25.00	464	294	10	107	540	2	441	1e-29	133
tr:W1FAC4_ENTCL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.56	384	261	10	7	379	4	377	1e-29	131
rs:WP_019264601	DNA topoisomerase I [Methanobrevibacter smithii].	27.94	544	322	21	7	532	5	496	1e-29	134
rs:WP_033627137	DNA topoisomerase, partial [Enterococcus faecium].	28.18	401	265	11	38	429	7	393	1e-29	130
rs:WP_031868979	DNA topoisomerase III, partial [Staphylococcus aureus].	30.09	319	204	10	254	559	15	327	1e-29	132
rs:WP_015319853	DNA topoisomerase I [Natronococcus occultus].	23.82	550	364	17	7	541	4	513	1e-29	134
rs:WP_008312743	DNA topoisomerase I [Haloarcula amylolytica].	23.78	614	403	16	7	603	4	569	1e-29	134
tr:A0A090RXB4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.73	271	174	6	251	512	24	292	1e-29	129
rs:WP_022010557	DNA topoisomerase [Firmicutes bacterium CAG:646].	31.23	301	186	9	262	544	43	340	1e-29	132
rs:WP_041329053	hypothetical protein, partial [Rubrobacter xylanophilus].	23.96	601	390	18	7	589	4	555	1e-29	134
rs:WP_042712403	DNA topoisomerase III, partial [Klebsiella cf. planticola B43].	30.29	350	212	13	7	340	4	337	1e-29	130
tr:B0TFR0_HELMI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.42	590	371	20	5	550	3	567	1e-29	134
rs:WP_044904480	DNA topoisomerase III, partial [Lachnospiraceae bacterium 3-2].	27.09	454	269	15	111	539	1	417	1e-29	133
tr:Q1AUL7_RUBXD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.96	601	390	18	7	589	4	555	1e-29	134
rs:WP_004591511	DNA topoisomerase I [Haloarcula japonica].	24.17	604	393	17	7	589	4	563	1e-29	134
tr:T3QN90_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.60	430	272	12	170	590	11	414	1e-29	132
rs:WP_005538001	DNA topoisomerase I [Haloarcula argentinensis].	24.26	606	390	17	7	589	4	563	2e-29	134
rs:WP_002347691	hypothetical protein, partial [Enterococcus faecium].	28.21	397	262	11	42	429	4	386	2e-29	130
tr:E4LJS5_9FIRM	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EFR40693.1};	37.05	224	119	7	329	538	1	216	2e-29	130
rs:WP_002348823	DNA topoisomerase, partial [Enterococcus faecium].	27.25	411	271	10	170	563	29	428	2e-29	132
rs:WP_032566798	DNA topoisomerase I, partial [Bacteroides fragilis].	25.87	433	288	12	167	591	19	426	2e-29	132
rs:WP_014040904	DNA topoisomerase I [Haloarcula hispanica].	24.17	604	393	16	7	589	4	563	2e-29	134
rs:WP_012035171	DNA topoisomerase I [Methanocella arvoryzae].	25.97	516	322	16	34	539	34	499	2e-29	134
tr:A0A0B5GGX8_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.17	604	393	16	7	589	4	563	2e-29	134
tr:A0A069D2D9_9LACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.97	377	217	14	213	563	1	356	2e-29	131
rs:WP_011170900	DNA topoisomerase I [Methanococcus maripaludis].	27.08	554	326	22	7	539	5	501	2e-29	134
rs:WP_040154704	DNA topoisomerase III, partial [Klebsiella pneumoniae].	31.40	293	171	6	221	489	1	287	2e-29	127
rs:WP_043881503	DNA topoisomerase III, partial [Vibrio cholerae].	28.02	364	211	12	8	344	6	345	3e-29	129
rs:WP_021060176	Topoisomerase IA, partial [Halonotius sp. J07HN6].	24.12	626	394	21	7	595	8	589	3e-29	133
gpu:CP006256_3668	Topoisomerase IA [Pseudomonas syringae pv. syringae HS191]	32.94	255	150	7	8	258	5	242	3e-29	130
gpu:CP006256_3668	Topoisomerase IA [Pseudomonas syringae pv. syringae HS191]	31.68	161	106	3	202	359	273	432	2e-12	80.1
rs:WP_031892888	DNA topoisomerase III, partial [Staphylococcus aureus].	27.34	384	238	13	7	380	5	357	3e-29	129
rs:WP_006734849	DNA topoisomerase [Lactobacillus iners].	27.00	574	349	19	5	536	3	548	3e-29	133
gp:CP008854_358	DNA topoisomerase III [Bacillus anthracis]	32.58	267	143	9	306	548	8	261	3e-29	130
tr:K8CP04_CROSK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	29.45	309	198	10	43	340	2	301	3e-29	128
rs:WP_036857354	DNA topoisomerase I, partial [Prevotella amnii].	25.25	495	304	17	5	474	3	456	3e-29	130
tr:A0A099T0T3_METMT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.79	605	367	23	4	588	15	551	3e-29	133
rs:WP_032845637	DNA topoisomerase I [Bacteroides ovatus].	25.26	570	371	18	4	550	1	538	3e-29	133
rs:WP_038231122	DNA topoisomerase, partial [Xylella fastidiosa].	28.21	351	229	8	8	346	5	344	3e-29	128
rs:WP_046058708	DNA topoisomerase III, partial [Clostridium sp. IBUN13A].	29.11	292	193	7	279	559	44	332	3e-29	131
rs:WP_042994626	DNA topoisomerase I [Bacteroides fragilis].	25.26	570	371	18	4	550	1	538	4e-29	132
rs:WP_032946838	hypothetical protein [Lactococcus lactis].	25.35	564	347	24	7	539	5	525	4e-29	132
rs:WP_025700989	hypothetical protein, partial [Paenibacillus forsythiae].	28.78	337	211	9	7	339	5	316	4e-29	127
tr:S6EZC3_LACLL	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.35	564	347	24	7	539	9	529	4e-29	132
rs:WP_006076577	DNA topoisomerase I [Halococcus saccharolyticus].	25.63	554	343	22	7	539	4	509	4e-29	133
rs:WP_023036564	hypothetical protein [Fusobacterium nucleatum].	24.25	536	334	15	42	540	38	538	4e-29	132
rs:WP_038233057	DNA topoisomerase, partial [Xylella fastidiosa].	27.92	351	230	8	8	346	5	344	4e-29	128
rs:WP_038284267	DNA topoisomerase, partial [Xylella fastidiosa].	28.49	351	228	9	8	346	5	344	5e-29	128
gpu:CP009505_1773	DNA topoisomerase I [Methanosarcina sp. MTP4]	26.13	555	328	21	75	595	62	568	5e-29	132
rs:WP_002352683	toprim domain protein, partial [Enterococcus faecium].	29.74	343	219	11	5	339	3	331	6e-29	127
sp:TOP1_PYRHO	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.80	625	366	25	7	589	4	566	6e-29	132
tr:W4LDQ7_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.01	355	223	9	8	357	1	331	6e-29	128
tr:D6CZ79_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.33	471	279	15	97	544	42	467	6e-29	132
rs:WP_032991710	DNA topoisomerase III, partial [Cronobacter dublinensis].	29.77	309	197	10	43	340	2	301	6e-29	127
rs:WP_015413028	DNA topoisomerase I [Methanosarcina mazei].	26.08	556	334	19	75	601	62	569	6e-29	132
rs:WP_036381281	hypothetical protein [Mogibacterium timidum].	24.78	573	371	19	3	546	2	543	6e-29	132
rs:WP_013826367	DNA topoisomerase I [Methanobacterium paludis].	27.11	546	323	22	7	530	5	497	6e-29	132
rs:WP_040223245	DNA topoisomerase III, partial [Klebsiella pneumoniae].	29.08	368	230	9	170	516	6	363	6e-29	128
rs:WP_046438492	DNA topoisomerase III, partial [Ruminococcus sp. UNK.MGS-30].	28.65	342	209	10	7	344	5	315	6e-29	127
rs:WP_026605122	DNA topoisomerase [Methylobacterium sp. 285MFTsu5.1].	25.44	562	345	21	29	540	11	548	6e-29	132
rs:WP_031892894	DNA topoisomerase III, partial [Staphylococcus aureus].	30.99	284	178	9	288	559	1	278	6e-29	127
rs:WP_044064261	DNA topoisomerase I, partial [Prevotella saccharolytica].	26.05	453	298	11	65	498	3	437	7e-29	129
gpu:CP009518_720	DNA topoisomerase I [Methanococcoides methylutens MM1]	23.75	602	387	18	7	589	4	552	7e-29	132
rs:WP_008802992	DNA topoisomerase III [Fusobacterium nucleatum].	25.95	578	362	19	7	548	6	553	7e-29	132
tr:A0A0B0HYH2_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.74	341	216	11	7	344	5	321	7e-29	128
rs:WP_044124897	DNA topoisomerase I, partial [Prevotella loescheii].	26.74	430	264	13	4	420	2	393	8e-29	129
rs:WP_023040405	DNA topoisomerase III [Fusobacterium nucleatum].	26.42	583	353	21	7	548	6	553	8e-29	132
tr:E2ZFS1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.55	544	336	20	72	590	2	501	9e-29	131
rs:WP_038684634	hypothetical protein, partial [Rubrobacter radiotolerans].	25.61	578	361	19	7	567	4	529	9e-29	131
tr:N1ZTU5_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EMZ19346.1};	27.78	414	248	12	145	539	4	385	9e-29	130
rs:WP_006664395	DNA topoisomerase I [Natrialba aegyptia].	23.64	550	364	17	7	541	4	512	1e-28	132
rs:WP_010546708	DNA topoisomerase I, partial [Halobiforma lacisalsi].	22.55	550	372	15	7	541	4	514	1e-28	131
tr:A0A023X4A7_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.78	578	360	20	7	567	4	529	1e-28	131
rs:WP_022300463	DNA topoisomerase III [Erysipelotrichaceae bacterium CAG:64].	26.36	459	293	13	101	531	4	445	1e-28	131
rs:WP_009366453	DNA topoisomerase I [Halogranum salarium].	23.80	563	358	18	7	541	8	527	1e-28	131
rs:WP_021073552	DNA topoisomerase I [haloarchaeon 3A1_DGR].	23.50	583	354	18	7	539	8	548	1e-28	131
rs:WP_025867914	DNA topoisomerase I, partial [Bacteroides nordii].	29.50	400	241	14	4	389	1	373	1e-28	127
tr:F6IZ93_LACPE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.93	426	263	13	200	603	23	426	1e-28	129
tr:W6N420_CLOTY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.21	384	233	12	162	533	12	372	1e-28	130
rs:WP_013718626	DNA topoisomerase I [Methanosaeta concilii].	24.76	513	315	14	75	562	54	520	1e-28	131
rs:WP_031903950	DNA topoisomerase III, partial [Staphylococcus aureus].	30.97	381	240	11	170	544	14	377	1e-28	129
tr:A0A0B3AFU7_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.43	569	355	20	3	553	2	513	1e-28	131
rs:WP_013999415	DNA topoisomerase I [Methanococcus maripaludis].	26.90	554	327	22	7	539	5	501	1e-28	131
rs:WP_034530646	DNA topoisomerase I, partial [Parabacteroides sp. 20_3].	29.50	400	241	14	4	389	1	373	1e-28	127
rs:WP_032838476	DNA topoisomerase I [Fusobacterium sp. CM1].	26.24	583	354	20	7	548	6	553	1e-28	131
rs:WP_021844917	DNA topoisomerase [Blautia hydrogenotrophica CAG:147].	30.09	422	242	16	157	532	21	435	1e-28	129
rs:WP_005681887	DNA topoisomerase I [Bacteroides caccae].	26.15	455	276	14	97	536	42	451	1e-28	130
rs:WP_011570557	DNA topoisomerase I [Haloquadratum walsbyi].	23.74	556	364	17	7	539	8	526	1e-28	131
tr:Q4MMD9_BACCE	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:AJI07793.1};	29.31	389	246	16	7	383	4	375	1e-28	127
rs:WP_017161855	hypothetical protein, partial [Xanthomonas axonopodis].	28.40	324	209	9	7	322	4	312	1e-28	126
tr:E1YZG1_9PORP	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EFK61037.1}; Flags: Fragment;	29.43	401	242	14	3	389	19	392	2e-28	127
rs:WP_014555165	DNA topoisomerase I [Haloquadratum walsbyi].	23.74	556	364	17	7	539	8	526	2e-28	131
rs:WP_025790155	DNA topoisomerase I, partial [Prevotella loescheii].	25.49	459	295	13	5	452	3	425	2e-28	127
rs:WP_013295046	DNA topoisomerase I [Methanothermobacter marburgensis].	26.66	574	321	24	6	549	4	507	2e-28	130
rs:WP_013023049	DNA topoisomerase I [Helicobacter mustelae].	28.15	444	264	13	89	505	59	474	2e-28	130
rs:WP_007140501	DNA topoisomerase I [Halobiforma lacisalsi].	22.43	602	403	18	7	587	4	562	2e-28	131
rs:WP_021787017	hypothetical protein, partial [Ferroplasma sp. Type II].	25.26	570	357	20	7	563	2	515	2e-28	130
tr:C7DGI7_MICA2	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.27	572	329	26	5	549	3	514	2e-28	130
rs:WP_028896239	DNA topoisomerase I [Prevotella sp. HUN102].	25.17	572	351	23	4	540	1	530	2e-28	130
rs:WP_047021469	hypothetical protein [Lactobacillus brevis].	26.56	610	370	23	8	590	5	563	2e-28	130
rs:WP_013867618	DNA topoisomerase I [Methanothermococcus okinawensis].	27.39	595	360	27	7	584	5	544	2e-28	130
gpu:CP009511_1531	DNA topoisomerase I [Methanosarcina mazei SarPi]	25.90	556	335	19	75	601	62	569	2e-28	130
rs:WP_023408496	hypothetical protein [uncultured Desulfofustis sp. PB-SRB1].	28.27	421	248	19	1	391	1	397	2e-28	127
rs:WP_011971973	DNA topoisomerase I [Methanococcus vannielii].	25.73	548	341	19	7	539	5	501	2e-28	130
tr:G9QDN0_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.79	418	277	9	133	539	4	403	2e-28	130
rs:WP_006723677	DNA topoisomerase [Collinsella intestinalis].	25.84	538	338	17	65	587	109	600	2e-28	130
tr:R2V5M3_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.69	390	260	11	5	386	3	378	3e-28	127
rs:WP_032739622	DNA topoisomerase III, partial [Klebsiella pneumoniae].	31.15	244	158	5	315	552	5	244	3e-28	125
rs:WP_011998043	DNA topoisomerase I [Ignicoccus hospitalis].	26.27	590	366	23	1	578	1	533	3e-28	130
rs:WP_022757655	hypothetical protein [Butyrivibrio fibrisolvens].	27.77	605	365	26	7	579	4	568	3e-28	130
tr:H3RLD1_PANSE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EHT97815.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EHT97815.1};	27.70	444	289	11	112	531	25	460	3e-28	129
rs:WP_044310449	DNA topoisomerase III, partial [Pseudomonas syringae].	35.22	247	145	6	108	347	1	239	3e-28	124
rs:WP_006056449	DNA topoisomerase I [Halogeometricum borinquense].	23.99	542	354	16	7	532	8	507	3e-28	130
rs:WP_008018278	DNA topoisomerase, partial [Bacteroides xylanisolvens].	24.79	468	313	10	97	550	21	463	3e-28	127
tr:I2WFK0_ECOLX	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EII23428.1};	26.98	341	234	8	8	345	5	333	3e-28	125
rs:WP_032706893	DNA topoisomerase III, partial [Pseudomonas savastanoi].	34.84	221	125	6	8	224	5	210	3e-28	122
tr:T0L554_9NEIS	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	27.78	396	248	12	1	389	1	365	4e-28	126
rs:WP_013329862	DNA topoisomerase I [Methanolacinia petrolearia].	25.70	498	306	16	48	532	48	494	4e-28	130
rs:WP_036668036	topoisomerase I, partial [Pediococcus acidilactici].	29.02	386	236	12	200	563	1	370	4e-28	128
rs:WP_021368817	DNA topoisomerase, partial [Peptoclostridium difficile].	28.74	334	203	12	7	337	4	305	4e-28	124
rs:WP_011223762	DNA topoisomerase I [Haloarcula marismortui].	24.55	505	344	13	7	498	4	484	4e-28	130
rs:WP_031860269	DNA topoisomerase III, partial [Staphylococcus aureus].	28.07	342	214	11	7	344	5	318	4e-28	125
rs:WP_021792813	hypothetical protein [Thermoplasmatales archaeon E-plasma].	26.55	501	301	17	75	553	60	515	4e-28	129
rs:WP_021789620	hypothetical protein [Thermoplasmatales archaeon Gpl].	24.73	562	360	17	5	553	8	519	4e-28	130
rs:WP_031837088	DNA topoisomerase III, partial [Staphylococcus aureus].	28.07	342	214	11	7	344	5	318	4e-28	125
rs:WP_038270228	hypothetical protein, partial [[Clostridium] clostridioforme].	26.70	457	270	15	112	548	1	412	5e-28	128
tr:G1VGY7_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGW46163.1};	25.54	466	300	13	5	459	3	432	5e-28	127
rs:WP_007953650	DNA topoisomerase I [Pelosinus fermentans].	25.56	622	356	22	7	593	6	555	5e-28	129
rs:WP_016292371	DNA topoisomerase III [Lachnospiraceae bacterium 28-4].	27.58	417	245	13	170	563	52	434	5e-28	128
rs:WP_031875882	DNA topoisomerase III, partial [Staphylococcus aureus].	28.07	342	214	11	7	344	5	318	5e-28	125
gpu:CP009512_1612	DNA topoisomerase I [Methanosarcina mazei S-6]	25.90	556	335	19	75	601	62	569	5e-28	129
rs:WP_021049991	Topoisomerase IA [Haloquadratum walsbyi].	23.92	556	363	18	7	539	8	526	5e-28	129
rs:WP_007934880	MULTISPECIES: DNA topoisomerase I [Pelosinus].	25.56	622	356	22	7	593	6	555	5e-28	129
rs:WP_022541864	DNA topoisomerase I [Aeropyrum camini].	25.09	570	364	19	2	554	16	539	5e-28	129
rs:WP_000596661	hypothetical protein, partial [Shigella boydii].	30.27	261	172	4	288	539	1	260	6e-28	125
rs:WP_004517003	DNA topoisomerase I [Haloarcula vallismortis].	23.57	594	389	16	7	581	4	551	6e-28	129
rs:WP_001689493	DNA topoisomerase, partial [Escherichia coli].	28.05	435	276	11	124	531	1	425	6e-28	128
rs:WP_001689137	DNA topoisomerase, partial [Escherichia coli].	28.05	435	276	11	124	531	1	425	6e-28	128
gpu:CP009501_559	DNA topoisomerase I [Methanosarcina thermophila TM-1]	25.82	546	331	19	36	562	44	534	6e-28	129
rs:WP_007187672	DNA topoisomerase I [Haloarcula californiae].	24.55	505	344	13	7	498	4	484	7e-28	129
rs:WP_022238218	DNA topoisomerase [Clostridium sp. CAG:343].	30.69	290	162	10	279	532	33	319	7e-28	125
rs:WP_013881179	DNA topoisomerase I [Halopiger xanaduensis].	23.19	608	396	21	7	589	4	565	7e-28	129
rs:WP_042253559	hypothetical protein [Lactobacillus brevis].	26.23	610	372	23	8	590	6	564	7e-28	129
rs:WP_040180632	DNA topoisomerase III, partial [Klebsiella pneumoniae].	29.71	340	211	9	229	543	7	343	8e-28	127
rs:WP_005553766	DNA topoisomerase I [Natronococcus amylolyticus].	23.45	550	366	17	7	541	4	513	8e-28	129
rs:WP_046864111	DNA topoisomerase [Microvirga sp. JC119].	24.68	551	347	19	29	532	20	549	8e-28	129
rs:WP_039106749	hypothetical protein [Lactobacillus brevis].	26.12	605	379	21	8	590	5	563	9e-28	128
rs:WP_006109876	DNA topoisomerase I [Natrialba asiatica].	23.82	550	363	16	7	541	4	512	9e-28	129
rs:WP_033669627	DNA topoisomerase III, partial [Bacillus cereus].	29.05	358	230	13	7	356	4	345	9e-28	125
tr:T1AUZ1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD60138.1}; Flags: Fragment;	28.40	338	219	8	216	539	2	330	9e-28	124
tr:R3GZL3_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.35	346	201	14	1	337	1	315	9e-28	124
rs:WP_006825523	DNA topoisomerase I [Natrialba taiwanensis].	23.82	550	363	16	7	541	4	512	1e-27	129
rs:WP_015732803	DNA topoisomerase I [Methanocaldococcus vulcanius].	29.42	503	308	20	7	495	5	474	1e-27	129
rs:WP_040152278	DNA topoisomerase III, partial [Xanthomonas citri].	34.11	214	135	4	200	408	17	229	1e-27	122
rs:WP_004367385	DNA topoisomerase TopB, partial [Prevotella nigrescens].	25.50	447	288	12	118	550	1	416	1e-27	127
rs:WP_044962176	DNA topoisomerase III, partial [Blautia sp. KLE 1732].	27.85	395	236	13	7	391	4	359	1e-27	124
rs:WP_012376245	DNA topoisomerase [Opitutus terrae].	24.72	623	402	23	7	573	6	617	1e-27	128
rs:WP_005581320	DNA topoisomerase I [Natronobacterium gregoryi].	23.59	551	364	19	7	541	4	513	1e-27	128
rs:WP_004038803	DNA topoisomerase I [Methanofollis liminatans].	24.03	516	324	16	48	550	48	508	1e-27	129
rs:WP_046988255	DNA topoisomerase III, partial [Thermomonas brevis].	36.42	173	102	3	8	180	5	169	1e-27	120
tr:B6FVP8_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	26.73	505	324	17	23	488	3	500	1e-27	126
tr:R8S7W4_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.05	358	230	13	7	356	4	345	1e-27	124
rs:YP_004289757	DNA topoisomerase i [Methanobacterium lacus].	27.45	550	316	23	7	530	5	497	1e-27	128
rs:WP_016301096	hypothetical protein [Lachnospiraceae bacterium COE1].	26.71	438	253	18	136	544	9	407	1e-27	127
rs:WP_021040976	Topoisomerase IA [Halonotius sp. J07HN4].	23.12	558	367	15	7	539	8	528	1e-27	128
rs:WP_034303586	DNA topoisomerase III, partial [Bacillus sp. 123MFChir2].	28.13	391	252	16	7	385	4	377	1e-27	124
rs:WP_006649229	DNA topoisomerase I [Haloterrigena thermotolerans].	22.87	621	399	19	7	589	4	582	1e-27	128
rs:WP_010209953	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	34.39	221	126	6	8	224	4	209	1e-27	121
rs:WP_023847589	DNA topoisomerase I, partial [Porphyromonas gingivalis].	27.13	435	252	16	7	417	4	397	1e-27	125
rs:WP_044988648	DNA topoisomerase III, partial [Tyzzerella nexilis].	27.38	493	313	18	35	488	9	495	2e-27	125
rs:WP_004957538	DNA topoisomerase I [Haloarcula sinaiiensis].	24.36	505	345	13	7	498	4	484	2e-27	128
tr:D2U1Z5_9ENTR	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:CBA74913.1}; Flags: Fragment;	27.34	395	268	12	18	407	5	385	2e-27	124
rs:WP_042993550	DNA topoisomerase I, partial [Bordetella bronchiseptica].	26.24	526	306	18	5	505	3	471	2e-27	126
tr:C7GHN5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.83	436	257	14	129	539	2	400	2e-27	127
rs:WP_033160575	DNA topoisomerase I, partial [Bacteroides cellulosilyticus].	29.89	368	218	14	202	552	16	360	2e-27	126
rs:WP_016284600	DNA topoisomerase III [Lachnospiraceae bacterium A4].	27.78	450	270	14	136	563	18	434	2e-27	127
rs:WP_009140840	DNA topoisomerase [Collinsella tanakaei].	24.85	511	331	15	65	563	108	577	2e-27	128
tr:A0A0B3AMM6_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.31	574	341	26	7	565	4	510	2e-27	127
gpu:CP009513_1559	DNA topoisomerase I [Methanosarcina mazei LYC]	25.72	556	336	19	75	601	62	569	2e-27	127
rs:WP_038308316	DNA topoisomerase III, partial [Kingella kingae].	24.42	520	328	14	46	532	24	511	2e-27	127
rs:WP_044153114	hypothetical protein [Salinibacillus aidingensis].	24.22	512	345	16	44	528	44	539	2e-27	127
rs:WP_020304534	DNA topoisomerase III, partial [Pseudomonas syringae].	28.36	335	207	8	256	565	38	364	2e-27	125
rs:WP_014868235	DNA topoisomerase I [Methanoculleus bourgensis].	24.56	509	330	15	48	550	48	508	2e-27	127
rs:WP_006746967	DNA topoisomerase I [Thioalkalivibrio thiocyanoxidans].	27.43	536	306	21	7	505	6	495	2e-27	127
rs:WP_021970827	DNA topoisomerase [Bacteroides sp. CAG:1076].	30.03	333	203	11	210	531	6	319	2e-27	125
tr:A0A063ZJV9_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.30	572	351	22	7	541	4	530	2e-27	127
tr:A0A0B3B3K1_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.04	477	282	15	78	531	7	440	2e-27	127
rs:WP_011034974	DNA topoisomerase I [Methanosarcina mazei].	25.72	556	336	19	75	601	62	569	2e-27	127
tr:B1M8L6_METRJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.42	557	357	18	29	540	2	539	2e-27	127
rs:WP_013708289	DNA topoisomerase [Coriobacterium glomerans].	24.95	513	328	15	65	563	108	577	2e-27	127
rs:WP_013798929	DNA topoisomerase I [Methanotorris igneus].	29.86	509	304	21	4	495	2	474	3e-27	128
rs:WP_031786349	DNA topoisomerase III, partial [Staphylococcus aureus].	31.34	351	221	9	200	544	12	348	3e-27	124
rs:WP_043342545	DNA topoisomerase [Methylobacterium sp. EUR3 AL-11].	24.42	557	357	18	29	540	11	548	3e-27	127
rs:WP_008451377	DNA topoisomerase, partial [Prevotella amnii].	26.27	472	271	14	107	531	52	493	3e-27	127
rs:WP_033617346	topoisomerase I, partial [Lactobacillus plantarum].	29.65	371	227	13	213	563	8	364	3e-27	123
rs:WP_007979591	DNA topoisomerase I [Haladaptatus paucihalophilus].	22.57	545	376	14	7	541	4	512	3e-27	127
tr:U2DIJ0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.85	395	236	13	7	391	11	366	3e-27	124
rs:WP_041373011	DNA topoisomerase [Methylobacterium radiotolerans].	24.42	557	357	18	29	540	11	548	3e-27	127
rs:WP_044423340	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	37.57	173	100	3	8	180	5	169	3e-27	119
tr:A0A034TX81_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.45	209	132	4	255	459	6	213	3e-27	121
rs:WP_032242256	DNA topoisomerase III, partial [Escherichia coli].	28.54	410	262	14	7	405	4	393	3e-27	123
rs:WP_021055826	Topoisomerase IA [Haloquadratum walsbyi].	24.04	549	357	16	7	532	8	519	3e-27	127
rs:WP_016357804	DNA topoisomerase I TopA [Methanobrevibacter sp. AbM4].	28.10	548	315	21	7	532	5	495	4e-27	127
rs:WP_007315375	DNA topoisomerase I [Methanolinea tarda].	23.68	511	332	18	48	550	48	508	4e-27	127
rs:WP_005352530	hypothetical protein [[Eubacterium] siraeum].	25.05	495	325	19	135	607	4	474	4e-27	126
rs:WP_040682411	DNA topoisomerase I, partial [Methanobrevibacter boviskoreani].	28.10	548	315	21	7	532	5	495	4e-27	126
rs:WP_006091896	DNA topoisomerase I [Natronorubrum tibetense].	23.51	553	366	18	7	541	4	517	4e-27	127
rs:WP_006429603	DNA topoisomerase I [Natrinema versiforme].	24.14	551	360	18	7	541	4	512	4e-27	127
rs:WP_006182012	DNA topoisomerase I [Natrinema pellirubrum].	22.52	564	370	16	7	541	4	529	5e-27	127
rs:WP_012617952	DNA topoisomerase I [Methanosphaerula palustris].	24.68	470	305	13	88	550	81	508	5e-27	127
rs:WP_032312320	DNA topoisomerase III, partial [Escherichia coli].	27.21	441	281	10	119	531	1	429	5e-27	125
rs:WP_032596671	DNA topoisomerase I, partial [Bacteroides fragilis].	26.45	431	279	12	167	592	44	441	5e-27	125
rs:WP_034054047	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	39.31	173	97	4	8	180	5	169	5e-27	118
rs:WP_005022546	DNA topoisomerase I [Helicobacter pullorum].	25.91	579	356	18	47	599	20	551	5e-27	126
rs:WP_017262381	hypothetical protein [Lactobacillus rossiae].	22.38	621	423	16	5	602	8	592	5e-27	126
rs:WP_044647931	DNA topoisomerase III, partial [Paenibacillus terrae].	26.93	401	252	12	4	385	1	379	5e-27	122
rs:WP_005742386	DNA topoisomerase III [Pseudomonas amygdali].	23.64	664	408	24	6	580	5	658	6e-27	126
tr:W0JKP4_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.09	574	343	25	7	541	4	529	6e-27	126
rs:WP_043074761	DNA topoisomerase [Methylobacterium radiotolerans].	24.24	557	358	18	29	540	11	548	6e-27	126
rs:WP_002322909	DNA topoisomerase III, partial [Enterococcus faecium].	30.26	304	193	9	5	301	3	294	6e-27	121
tr:A0A099VSN8_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.68	623	363	22	7	599	5	557	7e-27	126
rs:WP_041269880	DNA topoisomerase III, partial [Geobacillus sp. WCH70].	31.10	254	162	7	300	544	2	251	7e-27	123
rs:WP_042971014	DNA topoisomerase I, partial [Bacteroides fragilis].	26.45	431	279	12	167	592	44	441	7e-27	125
rs:WP_043373106	DNA topoisomerase [Methylobacterium sp. L2-4].	24.24	557	358	18	29	540	11	548	7e-27	126
rs:WP_032734728	DNA topoisomerase I [Klebsiella oxytoca].	26.86	525	304	20	5	505	3	471	8e-27	125
rs:WP_031806817	DNA topoisomerase III, partial [Staphylococcus aureus].	27.03	344	218	10	170	504	22	341	8e-27	122
rs:WP_022211948	DNA topoisomerase [Clostridium sp. CAG:265].	26.40	394	258	13	7	385	5	381	8e-27	122
tr:H1PYH8_9FUSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.48	424	252	16	119	530	1	389	9e-27	124
rs:WP_011405969	DNA topoisomerase I [Methanosphaera stadtmanae].	27.81	543	322	23	7	530	5	496	9e-27	125
tr:A0A015W1D8_BACFG	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXY92028.1};	26.45	431	279	12	167	592	33	430	9e-27	124
rs:WP_015017538	DNA topoisomerase IA [Candidatus Nitrososphaera gargensis].	27.13	586	360	23	5	570	3	541	1e-26	125
rs:WP_033629053	DNA topoisomerase, partial [Enterococcus faecium].	26.42	424	254	13	136	539	19	404	1e-26	124
rs:WP_035960666	hypothetical protein, partial [Fusobacterium ulcerans].	29.41	425	253	16	118	530	6	395	1e-26	124
rs:WP_022655238	DNA topoisomerase I [Desulfovibrio sp. Dsv1].	28.17	426	253	16	107	505	72	471	1e-26	125
rs:WP_009368920	DNA topoisomerase I [Bilophila sp. 4_1_30].	28.19	454	265	17	81	505	46	467	1e-26	125
tr:D9ZB73_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.13	586	360	23	5	570	3	541	1e-26	125
rs:WP_006169072	DNA topoisomerase I [Natrialba chahannaoensis].	22.81	548	371	15	7	541	4	512	1e-26	125
rs:WP_023114036	hypothetical protein, partial [Pseudomonas aeruginosa].	35.05	214	120	6	8	217	5	203	1e-26	118
rs:WP_040103882	DNA topoisomerase III, partial [Paenibacillus polymyxa].	24.41	508	326	15	124	599	7	488	1e-26	125
rs:WP_038892183	DNA topoisomerase III, partial [Vibrio campbellii].	28.96	335	227	8	8	339	5	331	1e-26	121
rs:WP_013037640	DNA topoisomerase I [Methanohalophilus mahii].	23.42	602	388	20	7	589	4	551	1e-26	125
rs:WP_015286106	topoisomerase IA [Methanoregula formicica].	23.56	556	362	18	7	550	4	508	1e-26	125
rs:WP_011448040	DNA topoisomerase I [Methanospirillum hungatei].	24.28	556	357	19	7	550	4	507	1e-26	125
rs:WP_006064421	DNA topoisomerase I [Natronorubrum bangense].	23.23	551	367	18	7	541	4	514	1e-26	125
rs:WP_040235486	DNA topoisomerase III, partial [Klebsiella pneumoniae].	32.97	276	159	7	291	543	19	291	1e-26	123
rs:WP_017707273	hypothetical protein, partial [Pseudomonas syringae].	35.96	203	111	6	8	206	5	192	1e-26	117
rs:WP_034229263	hypothetical protein, partial [Lachnospiraceae bacterium 3-1].	25.84	445	284	11	111	539	1	415	1e-26	124
rs:WP_040177565	DNA topoisomerase III, partial [Klebsiella pneumoniae].	32.97	276	159	7	291	543	29	301	1e-26	123
rs:WP_023114038	hypothetical protein, partial [Pseudomonas aeruginosa].	35.05	214	120	6	8	217	5	203	1e-26	117
tr:S5VD34_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.99	345	220	11	5	339	3	332	2e-26	121
rs:WP_032542490	DNA topoisomerase I [Bacteroides fragilis].	25.93	455	277	14	97	536	42	451	2e-26	124
rs:WP_033474582	DNA topoisomerase I [Bordetella bronchiseptica].	26.43	526	305	19	5	505	3	471	2e-26	124
rs:WP_016276248	DNA topoisomerase III, partial [Bacteroides massiliensis].	29.68	374	215	16	200	552	10	356	2e-26	123
tr:W7KLC0_9CREN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.11	618	395	21	5	601	8	572	2e-26	124
rs:WP_031826156	DNA topoisomerase III, partial [Staphylococcus aureus].	30.94	265	166	8	306	559	7	265	2e-26	122
rs:WP_044860248	DNA topoisomerase III, partial [Enterobacter cloacae].	27.49	342	228	9	8	339	3	334	2e-26	120
rs:WP_031811092	DNA topoisomerase III, partial [Staphylococcus aureus].	30.94	265	166	8	306	559	4	262	2e-26	122
rs:WP_044860249	DNA topoisomerase III, partial [Enterobacter cloacae].	27.49	342	228	9	8	339	3	334	2e-26	120
rs:WP_008415922	DNA topoisomerase I [Halalkalicoccus jeotgali].	23.13	549	364	16	7	539	4	510	2e-26	124
tr:U2AIP4_XYLFS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.16	316	208	7	43	346	16	324	2e-26	120
rs:WP_026487967	DNA topoisomerase III [Butyrivibrio sp. XBB1001].	26.54	471	298	13	1	430	1	464	2e-26	124
rs:WP_038891121	DNA topoisomerase III, partial [Vibrio campbellii].	28.96	335	227	8	8	339	5	331	2e-26	120
rs:WP_034290689	DNA topoisomerase I [Helicobacter sp. MIT 11-5569].	25.09	586	358	20	47	599	20	557	2e-26	124
rs:WP_035137691	DNA topoisomerase [Collinsella sp. 4_8_47FAA].	25.29	522	319	17	65	563	108	581	3e-26	124
gpu:CP009507_1289	DNA topoisomerase I [Methanosarcina siciliae HI350]	25.78	543	328	19	75	589	62	557	3e-26	124
rs:WP_009278772	DNA topoisomerase [Olsenella sp. oral taxon 809].	24.58	537	351	18	65	587	109	605	3e-26	124
gpu:CP009506_1343	DNA topoisomerase I [Methanosarcina siciliae T4/M]	25.78	543	328	19	75	589	62	557	3e-26	124
tr:A0A0A7U5Q4_LACBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.75	382	246	11	200	563	1	370	3e-26	122
rs:WP_012939689	DNA topoisomerase I [Archaeoglobus profundus].	24.43	618	379	21	7	603	4	554	3e-26	124
rs:WP_023502268	Topoisomerase IA [uncultured archaeon A07HN63].	23.70	519	347	16	7	498	8	504	3e-26	124
rs:WP_015324220	DNA topoisomerase I, archaeal [Methanomethylovorans hollandica].	24.63	544	331	20	75	588	58	552	3e-26	124
rs:WP_016628541	DNA topoisomerase [Enterococcus faecium].	32.04	284	172	8	285	557	2	275	3e-26	120
rs:WP_022011364	DNA topoisomerase III [Bacteroides fragilis CAG:558].	25.39	453	269	14	177	602	1	411	3e-26	122
rs:WP_044999629	DNA topoisomerase III [Roseburia intestinalis].	27.03	418	243	14	147	539	6	386	4e-26	122
tr:A4EC43_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.29	522	319	17	65	563	30	503	4e-26	124
rs:WP_015300379	topoisomerase IA [Halovivax ruber].	22.64	605	397	21	2	581	21	579	4e-26	124
rs:WP_040359782	DNA topoisomerase [Collinsella aerofaciens].	25.29	522	319	17	65	563	108	581	4e-26	124
rs:WP_022093857	DNA topoisomerase [Collinsella sp. CAG:166].	25.29	522	319	17	65	563	108	581	4e-26	124
rs:WP_014865375	DNA topoisomerase I [Natrinema sp. J7-2].	25.56	536	334	18	75	581	54	553	4e-26	124
rs:WP_031834529	DNA topoisomerase III, partial [Staphylococcus aureus].	31.32	348	219	9	203	544	1	334	4e-26	121
rs:WP_044124831	DNA topoisomerase I, partial [Prevotella loescheii].	26.23	427	268	13	5	420	3	393	4e-26	120
tr:C3J9A0_9PORP	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEN83247.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EEN83247.1};	23.96	505	332	15	124	602	9	487	5e-26	122
rs:WP_040101183	DNA topoisomerase III, partial [Escherichia coli].	29.53	386	236	11	189	544	38	417	5e-26	122
rs:WP_002353327	DNA topoisomerase, partial [Enterococcus faecium].	27.95	347	226	10	165	498	24	359	5e-26	120
sp:TOP1_METTH	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.96	574	325	26	6	549	11	514	5e-26	123
tr:A0A0B3AMV3_9ARCH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KHO51615.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHO51615.1};	24.79	585	362	21	1	564	1	528	5e-26	123
gpu:CP009515_2186	DNA topoisomerase I [Methanosarcina lacustris Z-7289]	25.19	540	333	18	75	588	62	556	5e-26	123
rs:WP_008092043	DNA topoisomerase I [Haloferax prahovense].	22.97	627	414	20	7	607	8	591	5e-26	123
rs:WP_008778027	DNA topoisomerase III, partial [Parabacteroides sp. 20_3].	29.78	366	216	14	4	355	1	339	5e-26	119
tr:T0Y7L8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD31086.1}; Flags: Fragment;	29.55	291	191	5	263	550	1	280	5e-26	120
rs:WP_010939590	DNA topoisomerase III [Desulfovibrio vulgaris].	27.92	351	229	12	265	601	346	686	6e-26	123
rs:WP_010939590	DNA topoisomerase III [Desulfovibrio vulgaris].	26.01	273	176	7	3	264	2	259	3e-13	83.2
rs:WP_044061963	hypothetical protein, partial [Escherichia coli].	26.20	458	296	14	8	443	5	442	6e-26	120
rs:WP_006773686	DNA topoisomerase III, partial [[Clostridium] hathewayi].	27.84	370	224	11	199	550	3	347	6e-26	121
rs:WP_008896716	DNA topoisomerase I [Haloterrigena salina].	23.72	607	394	20	7	589	4	565	6e-26	123
rs:WP_005933789	DNA topoisomerase III [Faecalibacterium prausnitzii].	27.30	403	236	12	170	550	29	396	6e-26	122
rs:WP_008457790	DNA topoisomerase I [Natrinema gari].	23.96	551	361	18	7	541	4	512	6e-26	123
rs:WP_008577482	MULTISPECIES: DNA topoisomerase I [Haloferax].	23.24	555	364	17	7	541	8	520	6e-26	123
gpu:CP009516_2375	DNA topoisomerase I [Methanosarcina horonobensis HB-1]	25.90	556	335	20	75	601	62	569	7e-26	123
rs:WP_034663111	DNA topoisomerase I [Corynebacterium tuscaniense].	25.73	579	337	23	5	544	10	534	7e-26	123
rs:WP_024725066	hypothetical protein, partial [Clostridiales bacterium VE202-03].	32.91	234	139	7	5	236	4	221	7e-26	117
rs:WP_045121537	DNA topoisomerase, partial [Fusobacterium nucleatum].	26.47	374	235	11	56	419	7	350	7e-26	120
tr:L2HCI8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.37	363	242	9	213	563	1	357	7e-26	121
rs:WP_040580315	DNA topoisomerase I [Porphyromonas endodontalis].	23.96	505	332	15	124	602	47	525	7e-26	122
rs:WP_015790454	DNA topoisomerase I [Halorhabdus utahensis].	24.20	562	340	20	7	539	4	508	8e-26	123
tr:H1HI78_FUSNU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHO75743.1}; Flags: Fragment;	26.47	374	235	11	56	419	7	350	8e-26	120
rs:WP_021632671	toprim domain protein, partial [Clostridium sp. ATCC BAA-442].	32.91	234	139	7	5	236	4	221	8e-26	117
rs:WP_010916276	DNA topoisomerase I [Thermoplasma volcanium].	25.28	538	327	19	33	557	40	515	8e-26	122
tr:K1SJ22_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC47331.1}; Flags: Fragment;	32.06	262	149	7	279	529	2	245	9e-26	117
rs:WP_038671386	DNA topoisomerase I [Pelosinus sp. UFO1].	26.20	603	346	22	7	580	6	538	9e-26	122
tr:A0A0D6JSG2_9EURY	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:CQR50836.1};	22.70	555	367	16	7	541	8	520	9e-26	122
rs:WP_007697630	DNA topoisomerase I [Halovivax asiaticus].	22.67	600	393	21	7	581	4	557	9e-26	122
rs:WP_032825010	topoisomerase I, partial [Oenococcus oeni].	28.69	373	228	12	213	563	1	357	1e-25	119
tr:T2GJI9_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.71	595	335	27	6	563	4	528	1e-25	122
tr:K1TWC1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC77422.1}; Flags: Fragment;	27.58	359	221	11	4	357	1	325	1e-25	118
rs:WP_004970153	DNA topoisomerase I [Haloferax denitrificans].	22.97	627	414	20	7	607	8	591	1e-25	122
rs:WP_031796200	DNA topoisomerase III, partial [Staphylococcus aureus].	31.91	282	175	9	269	544	54	324	1e-25	119
rs:WP_040360493	DNA topoisomerase [Collinsella stercoris].	25.14	537	343	16	65	587	109	600	1e-25	122
rs:WP_038313770	DNA topoisomerase III [Kingella kingae].	25.11	462	287	12	105	532	33	469	1e-25	122
tr:N9YPK9_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ENZ09687.1};	26.00	450	268	15	119	548	1	405	1e-25	121
tr:I7KUW7_9CLOT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.14	528	311	18	3	504	2	476	1e-25	121
gpu:CP009504_1119	DNA topoisomerase I [Methanosarcina sp. WH1]	25.36	552	343	18	75	601	62	569	1e-25	122
tr:F0NX69_LACHH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.84	378	221	14	213	563	3	359	1e-25	120
tr:B6G8D3_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.14	537	343	16	65	587	122	613	1e-25	122
rs:WP_004972896	DNA topoisomerase I [Haloferax gibbonsii].	22.97	627	414	20	7	607	8	591	1e-25	122
rs:WP_034554683	DNA topoisomerase I [Helicobacter apodemus].	25.81	585	349	20	47	599	20	551	1e-25	122
rs:WP_015257273	DNA topoisomerase I [Thioalkalivibrio nitratireducens].	27.36	541	300	22	7	505	6	495	1e-25	122
rs:WP_006629579	DNA topoisomerase I [Halorubrum tebenquichense].	23.16	544	340	16	7	498	8	525	1e-25	122
rs:WP_025480891	DNA topoisomerase, partial [Enterococcus faecium].	27.81	392	255	10	192	563	3	386	1e-25	120
rs:WP_033628386	DNA topoisomerase, partial [Enterococcus faecalis].	27.14	409	276	11	147	544	9	406	1e-25	119
rs:WP_016228891	hypothetical protein [Lachnospiraceae bacterium 10-1].	27.95	390	225	15	162	531	38	391	1e-25	121
rs:WP_011791944	DNA topoisomerase III [Desulfovibrio vulgaris].	27.92	351	229	12	265	601	346	686	1e-25	122
rs:WP_011791944	DNA topoisomerase III [Desulfovibrio vulgaris].	26.01	273	176	7	3	264	2	259	5e-13	82.8
tr:U6FEN0_LACHE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.96	366	236	11	213	563	1	357	1e-25	120
rs:WP_042664917	hypothetical protein [Thaumarchaeota archaeon SCGC AB-179-E04].	26.00	573	348	23	2	553	4	521	1e-25	122
gpu:CP009503_1191	DNA topoisomerase I [Methanosarcina sp. WWM596]	25.36	552	343	18	75	601	62	569	2e-25	122
tr:J6WY89_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.81	392	255	10	192	563	3	386	2e-25	120
rs:WP_008527508	DNA topoisomerase I [Halorhabdus tiamatea].	23.91	552	354	17	7	539	4	508	2e-25	122
tr:C5ZW76_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.24	626	368	21	1	599	1	553	2e-25	122
tr:C6ANJ9_AGGAN	SubName: Full=DNA topoisomerase 3 (DNA topoisomerase III) {ECO:0000313|EMBL:ACS97410.1};	33.94	221	130	5	8	224	5	213	2e-25	115
rs:WP_025477514	DNA topoisomerase, partial [Enterococcus faecium].	28.97	359	230	12	5	355	3	344	2e-25	118
rs:WP_012942649	DNA topoisomerase I [Haloterrigena turkmenica].	23.87	553	360	18	7	541	4	513	2e-25	122
rs:WP_012799454	DNA topoisomerase [Slackia heliotrinireducens].	23.88	536	349	17	67	588	111	601	2e-25	122
rs:WP_025477723	DNA topoisomerase, partial [Enterococcus faecium].	28.97	359	230	12	5	355	3	344	2e-25	118
rs:WP_032996320	DNA topoisomerase III, partial [Aggregatibacter aphrophilus].	33.94	221	130	5	8	224	5	213	2e-25	115
tr:T8F165_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.97	359	230	12	5	355	4	345	2e-25	118
rs:WP_038328472	DNA topoisomerase III [Kingella kingae].	24.14	497	313	14	72	532	1	469	2e-25	121
rs:WP_016317479	DNA topoisomerase III, partial [Anaerotruncus sp. G3(2012)].	27.98	361	212	11	210	549	5	338	2e-25	118
rs:WP_040682714	DNA topoisomerase I, partial [Methanocaldococcus villosus].	27.87	506	306	19	7	495	4	467	2e-25	122
rs:WP_007695272	DNA topoisomerase I [Halococcus hamelinensis].	25.18	552	352	22	7	541	4	511	2e-25	122
rs:WP_003368142	DNA topoisomerase III, partial [Pseudomonas syringae].	35.47	203	112	6	8	206	5	192	2e-25	114
rs:WP_021044116	DNA topoisomerase I [halophilic archaeon J07HX64].	23.68	549	358	17	7	539	4	507	2e-25	122
rs:WP_045135956	DNA topoisomerase, partial [Enterococcus faecium].	26.59	440	302	11	117	544	4	434	2e-25	121
rs:WP_002819867	hypothetical protein [Oenococcus oeni].	28.95	373	227	13	213	563	1	357	2e-25	120
tr:D3LK86_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.97	359	230	12	5	355	4	345	2e-25	117
rs:WP_040153697	DNA topoisomerase III, partial [Klebsiella pneumoniae].	32.09	268	160	9	8	269	5	256	2e-25	116
gpu:CP009524_1651	DNA topoisomerase I [Methanosarcina sp. Kolksee]	24.96	569	358	19	48	601	55	569	2e-25	121
rs:WP_006655377	DNA topoisomerase I [Helicobacter canadensis].	25.56	583	353	19	47	599	20	551	2e-25	121
rs:WP_019389429	hypothetical protein [Kingella kingae].	24.14	497	313	14	72	532	1	469	2e-25	121
rs:WP_033602985	DNA topoisomerase, partial [Enterococcus faecalis].	25.84	418	292	9	136	544	19	427	2e-25	120
rs:WP_013776134	DNA topoisomerase I [Acidianus hospitalis].	25.18	552	354	20	76	606	7	520	2e-25	120
rs:WP_004057583	DNA topoisomerase I [Haloferax mediterranei].	22.89	629	412	20	7	607	8	591	2e-25	121
tr:L2IN04_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELA69015.1};	27.91	344	227	9	201	531	38	373	2e-25	118
rs:WP_033739473	DNA topoisomerase I [Helicobacter pylori].	27.78	450	259	15	89	505	59	475	3e-25	121
tr:F7JP30_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.62	272	154	8	297	539	4	272	3e-25	119
rs:WP_025481759	DNA topoisomerase [Enterococcus faecium].	31.83	289	176	8	279	556	43	321	3e-25	119
rs:WP_042702305	DNA topoisomerase I [Methanobrevibacter arboriphilus].	26.97	545	333	23	7	532	5	503	3e-25	121
tr:A0A0D8DM63_9EURY	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJE49771.1};	24.61	581	356	17	3	564	2	519	3e-25	121
rs:WP_006672595	DNA topoisomerase I [Halobiforma nitratireducens].	23.32	609	395	23	7	589	4	566	3e-25	121
rs:WP_042441694	DNA topoisomerase III, partial [Rhodopseudomonas palustris].	30.25	238	145	6	313	530	6	242	3e-25	119
rs:WP_044155318	DNA topoisomerase I, partial [Bacteroides intestinalis].	25.86	406	269	11	135	531	23	405	3e-25	120
rs:WP_011647269	MULTISPECIES: DNA topoisomerase I [Hyphomonas].	26.47	529	309	21	7	505	4	482	3e-25	121
rs:WP_012901188	DNA topoisomerase I [Methanocella paludicola].	24.43	483	308	13	75	539	53	496	3e-25	120
rs:WP_045715631	DNA topoisomerase III, partial [Salmonella enterica].	29.27	386	237	11	189	544	11	390	3e-25	120
rs:WP_007257738	DNA topoisomerase I [Natronolimnobius innermongolicus].	23.68	608	394	22	7	589	4	566	3e-25	121
rs:WP_001719610	DNA topoisomerase III, partial [Salmonella enterica].	28.43	394	251	13	7	389	4	377	3e-25	117
rs:WP_004077426	DNA topoisomerase I [Methanoplanus limicola].	24.44	495	321	14	48	535	48	496	3e-25	121
rs:WP_044295331	DNA topoisomerase III [Pseudomonas amygdali].	31.58	228	138	5	338	549	183	408	3e-25	119
rs:WP_044295331	DNA topoisomerase III [Pseudomonas amygdali].	33.82	204	127	3	8	211	5	200	8e-25	118
rs:WP_029657351	DNA topoisomerase, partial [Enterococcus faecalis].	27.14	409	276	11	147	544	9	406	4e-25	119
tr:F3FB74_PSEA0	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH27460.1}; Flags: Fragment;	36.42	173	102	3	8	180	5	169	4e-25	113
rs:WP_027081111	DNA topoisomerase I [Luteimonas mephitis].	25.21	591	342	21	7	563	6	530	4e-25	120
tr:B3CB28_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EDV04280.1};	25.86	406	269	11	135	531	58	440	4e-25	120
tr:C7X7R3_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	24.32	518	342	14	48	544	3	491	4e-25	120
tr:R9N328_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS77715.1};	25.61	410	260	12	147	539	6	387	4e-25	119
rs:WP_021583868	DNA topoisomerase, partial [Prevotella pleuritidis].	25.16	461	294	13	5	452	3	425	4e-25	118
tr:R2NSX6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.27	415	248	13	145	539	3	379	4e-25	119
rs:WP_033603659	DNA topoisomerase, partial [Enterococcus faecalis].	26.04	407	283	9	147	544	9	406	4e-25	119
rs:WP_002418951	DNA topoisomerase, partial [Enterococcus faecalis].	27.65	340	214	9	7	344	6	315	4e-25	116
tr:K1URV5_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC74216.1}; Flags: Fragment;	28.74	348	198	11	7	343	5	313	4e-25	116
rs:WP_002338426	hypothetical protein, partial [Enterococcus faecium].	29.45	343	221	10	5	339	3	332	4e-25	117
rs:WP_044119591	DNA topoisomerase, partial [Staphylococcus aureus].	26.43	420	287	10	136	544	19	427	4e-25	119
tr:A0A075MM36_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.30	564	345	23	1	543	1	520	4e-25	120
rs:WP_036683311	DNA topoisomerase I, partial [Pelobacter seleniigenes].	27.10	535	305	22	7	505	6	491	5e-25	120
rs:WP_006450818	topoisomerase IA, partial [Xanthomonas gardneri].	30.80	250	148	10	291	520	2	246	5e-25	114
rs:WP_003703765	DNA topoisomerase I [Lactobacillus salivarius].	26.35	520	312	19	7	504	21	491	5e-25	120
rs:WP_033603135	DNA topoisomerase, partial [Enterococcus faecalis].	26.65	409	278	10	147	544	9	406	5e-25	118
tr:B7BDS6_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.08	381	243	12	177	550	1	357	5e-25	119
gpu:CP009520_1676	DNA topoisomerase I [Methanosarcina vacuolata Z-761]	24.78	569	359	19	48	601	55	569	5e-25	120
tr:C2EF62_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.73	520	310	20	7	504	33	503	5e-25	120
rs:WP_034918008	DNA topoisomerase III, partial [Candidatus Accumulibacter sp. BA-91].	27.32	421	243	15	170	550	2	399	5e-25	120
tr:V5EIH7_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.11	370	234	12	213	563	1	357	5e-25	119
rs:WP_011843614	DNA topoisomerase I [Methanoculleus marisnigri].	23.56	556	362	18	7	550	4	508	5e-25	120
rs:WP_031861946	DNA topoisomerase III, partial [Staphylococcus aureus].	30.16	368	234	12	140	501	1	351	5e-25	117
tr:Q6N2B4_RHOPA	SubName: Full=Complete genome; segment 14/16 {ECO:0000313|EMBL:CAE29577.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CAE29577.1};	29.66	263	159	7	293	530	87	348	5e-25	120
rs:WP_031929814	DNA topoisomerase, partial [Staphylococcus aureus].	26.04	407	283	9	147	544	2	399	5e-25	119
rs:WP_031884499	DNA topoisomerase III, partial [Staphylococcus aureus].	31.56	282	176	8	269	544	14	284	5e-25	117
rs:WP_033606624	DNA topoisomerase, partial [Enterococcus faecium].	29.45	343	221	10	5	339	3	332	5e-25	116
rs:WP_007275720	DNA topoisomerase I [Haloferax sulfurifontis].	22.81	627	415	20	7	607	8	591	5e-25	120
tr:J6U692_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.04	392	258	10	192	563	8	391	5e-25	118
tr:K4XDU0_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.83	333	220	9	67	391	6	329	6e-25	116
rs:WP_003710032	DNA topoisomerase I [Lactobacillus salivarius].	26.54	520	311	19	7	504	21	491	6e-25	120
rs:WP_011307376	DNA topoisomerase I [Methanosarcina barkeri].	25.46	538	332	18	75	587	62	555	6e-25	120
rs:WP_031611768	DNA topoisomerase III, partial [Salmonella enterica].	29.49	373	227	11	189	531	14	380	6e-25	119
gpu:CP009517_952	DNA topoisomerase I [Methanosarcina barkeri 3]	24.87	571	356	20	48	601	55	569	6e-25	120
rs:WP_047035564	DNA topoisomerase I [Lactobacillus salivarius].	26.35	520	312	19	7	504	21	491	6e-25	120
rs:WP_036140441	DNA topoisomerase I, partial [Lysobacter daejeonensis].	25.93	594	340	22	7	563	6	536	6e-25	120
rs:WP_002350554	toprim domain protein, partial [Enterococcus faecium].	30.29	307	189	10	5	301	3	294	6e-25	115
rs:WP_002409753	toprim domain protein, partial [Enterococcus faecalis].	31.47	251	156	8	5	248	3	244	6e-25	115
rs:WP_004044253	MULTISPECIES: DNA topoisomerase I [Haloferax].	23.06	555	365	17	7	541	8	520	6e-25	120
rs:WP_016384083	DNA topoisomerase I, partial [Lactobacillus paracasei].	26.83	533	310	21	1	504	1	482	6e-25	118
rs:WP_033615871	DNA topoisomerase, partial [Enterococcus faecium].	26.04	407	283	9	147	544	9	406	6e-25	119
rs:WP_019036494	hypothetical protein, partial [Prevotella amnii].	26.14	440	260	16	5	420	3	401	6e-25	117
tr:G9QZP7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.45	341	215	10	3	339	2	317	6e-25	116
rs:WP_032582746	DNA topoisomerase I, partial [Bacteroides fragilis].	26.42	405	267	11	136	531	9	391	6e-25	119
rs:WP_014052595	DNA topoisomerase I [halophilic archaeon DL31].	23.83	554	348	19	7	532	4	511	6e-25	120
tr:R1VFV3_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.88	391	260	11	165	544	8	387	6e-25	117
rs:WP_008582161	DNA topoisomerase I [Halorubrum hochstenium].	23.35	544	338	18	7	498	8	524	6e-25	120
rs:WP_032703532	DNA topoisomerase III, partial [Campylobacter coli].	30.00	310	183	9	280	559	21	326	6e-25	117
rs:WP_004051361	DNA topoisomerase I [Halococcus morrhuae].	24.14	551	360	20	7	541	4	512	6e-25	120
rs:WP_033629072	DNA topoisomerase, partial [Enterococcus faecium].	29.45	343	221	10	5	339	3	332	6e-25	116
rs:WP_011475885	DNA topoisomerase I [Lactobacillus salivarius].	26.35	520	312	19	7	504	21	491	6e-25	120
rs:WP_027242705	DNA topoisomerase I [Piscirickettsia salmonis].	25.46	538	313	17	7	505	6	494	7e-25	120
rs:WP_031879283	DNA topoisomerase III, partial [Staphylococcus aureus].	31.56	282	176	8	269	544	25	295	7e-25	117
rs:WP_008323216	DNA topoisomerase I [Haloferax elongans].	22.87	634	406	21	7	607	8	591	7e-25	120
tr:L2P8Z6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.45	343	221	10	5	339	3	332	7e-25	116
rs:WP_036819223	DNA topoisomerase I, partial [Piscirickettsia salmonis].	25.46	538	313	17	7	505	6	494	7e-25	119
tr:C0B625_9FIRM	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EEG91159.1};	28.74	348	198	11	7	343	4	312	8e-25	115
rs:WP_031921854	DNA topoisomerase III, partial [Staphylococcus aureus].	31.56	282	176	8	269	544	15	285	8e-25	117
rs:WP_031859981	DNA topoisomerase III, partial [Staphylococcus aureus].	31.34	335	210	11	5	332	3	324	8e-25	115
rs:WP_029675935	MULTISPECIES: DNA topoisomerase, partial [Bacilli].	25.84	418	292	9	136	544	19	427	8e-25	119
rs:WP_001241571	hypothetical protein, partial [Salmonella enterica].	32.26	217	137	3	7	223	4	210	8e-25	113
rs:WP_004064987	DNA topoisomerase I [Haloferax lucentense].	23.06	555	365	17	7	541	8	520	8e-25	119
rs:WP_012083020	DNA topoisomerase I [Nitratiruptor sp. SB155-2].	27.59	435	279	13	89	505	60	476	8e-25	119
rs:WP_023394812	DNA topoisomerase I [Candidatus Halobonum tyrrellensis].	23.42	568	361	15	7	541	4	530	8e-25	120
rs:WP_007545055	DNA topoisomerase I [Haloferax larsenii].	22.89	629	412	21	7	607	8	591	8e-25	119
rs:WP_044343070	DNA topoisomerase I [Pseudomonas oryzihabitans].	26.05	526	307	19	5	505	3	471	9e-25	119
rs:WP_031922934	DNA topoisomerase III, partial [Staphylococcus aureus].	31.25	256	159	8	315	559	3	252	9e-25	116
rs:WP_039993093	DNA topoisomerase [Slackia sp. CM382].	23.32	609	382	22	35	607	64	623	9e-25	119
rs:WP_034998089	DNA topoisomerase I [Lactobacillus salivarius].	26.35	520	312	19	7	504	21	491	9e-25	119
tr:R2NN65_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.14	345	216	11	5	339	3	332	9e-25	116
rs:WP_035145808	DNA topoisomerase I [Lactobacillus sakei].	24.80	613	357	21	1	581	1	541	9e-25	119
tr:C7UVJ8_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.84	418	292	9	136	544	31	439	1e-24	119
rs:WP_002825272	TraA family conjugation nicking enzyme, partial [Oenococcus oeni].	28.69	373	228	12	213	563	1	357	1e-24	117
rs:WP_032494175	topoisomerase I, partial [Enterococcus faecium].	25.78	419	293	9	135	544	19	428	1e-24	119
rs:WP_035457587	topoisomerase I, partial [Lactobacillus coryniformis].	28.08	381	246	12	200	563	8	377	1e-24	118
tr:J2Z439_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.08	381	246	12	200	563	16	385	1e-24	118
rs:WP_003706174	DNA topoisomerase I [Lactobacillus salivarius].	26.35	520	312	19	7	504	21	491	1e-24	119
rs:WP_016265142	DNA topoisomerase I [Lactobacillus sakei].	24.80	613	357	21	1	581	1	541	1e-24	119
tr:I6F131_SHIBO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.90	233	152	3	315	539	2	233	1e-24	115
rs:WP_011374691	DNA topoisomerase I [Lactobacillus sakei].	24.80	613	357	21	1	581	1	541	1e-24	119
tr:S5ZEH2_9CREN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AGT35503.1};	26.76	482	292	19	75	530	61	507	1e-24	119
tr:S6ULM2_PSESF	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EPN39347.1};	36.21	174	103	4	7	180	4	169	1e-24	112
tr:J6IWI6_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.32	609	382	22	35	607	62	621	1e-24	119
tr:R4EHX8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.37	391	262	10	165	544	8	387	1e-24	117
rs:WP_034983386	DNA topoisomerase I [Lactobacillus salivarius].	26.35	520	312	19	7	504	21	491	1e-24	119
rs:WP_034558194	DNA topoisomerase, partial [Carnobacterium gallinarum].	26.08	418	291	9	136	544	19	427	1e-24	119
rs:WP_044270718	DNA topoisomerase I [Candidatus Bacteroides timonensis].	23.88	578	354	24	4	550	1	523	1e-24	118
rs:WP_014406775	DNA topoisomerase I [Methanocella conradii].	23.91	481	313	12	75	539	53	496	1e-24	119
rs:WP_036592880	DNA topoisomerase III, partial [Paenibacillus sophorae].	26.89	331	213	9	7	333	5	310	1e-24	115
rs:WP_025480915	DNA topoisomerase, partial [Enterococcus faecalis].	26.74	389	267	9	165	544	12	391	1e-24	117
rs:WP_044261765	DNA topoisomerase I [Campylobacter jejuni].	25.80	438	283	13	89	505	60	476	1e-24	119
tr:I6H4J4_SHIFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.37	214	141	4	306	513	1	212	1e-24	113
rs:WP_033742789	DNA topoisomerase I [Helicobacter pylori].	28.00	450	258	16	89	505	59	475	1e-24	119
rs:WP_006185387	DNA topoisomerase I [Natrinema pallidum].	24.16	563	345	17	75	589	54	582	1e-24	119
rs:WP_019774270	hypothetical protein, partial [Streptococcus sobrinus].	26.01	446	278	14	5	430	3	416	1e-24	116
rs:WP_034276065	DNA topoisomerase III, partial [Bacillus sp. 171095_106].	27.49	371	233	12	7	360	4	355	1e-24	115
rs:WP_028641865	hypothetical protein [Novosphingobium acidiphilum].	24.62	455	293	12	105	531	47	479	1e-24	119
tr:U1QGR1_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.58	589	365	18	7	541	77	628	2e-24	119
rs:WP_025280338	DNA topoisomerase I [Ectothiorhodospira haloalkaliphila].	25.05	539	314	17	7	505	6	494	2e-24	119
rs:WP_008321710	DNA topoisomerase I [Haloferax mucosum].	22.26	557	367	16	7	541	8	520	2e-24	119
rs:WP_033760176	DNA topoisomerase I [Helicobacter pylori].	27.78	450	259	15	89	505	59	475	2e-24	119
rs:WP_024118415	DNA topoisomerase I [Helicobacter pylori].	28.00	450	258	16	89	505	59	475	2e-24	119
rs:WP_026937567	DNA topoisomerase I [Gulosibacter molinativorax].	25.84	623	344	21	7	579	6	560	2e-24	119
rs:WP_033744865	DNA topoisomerase I [Helicobacter pylori].	27.78	450	259	15	89	505	59	475	2e-24	118
tr:A0A089ZH13_METFO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.37	546	321	26	7	530	5	491	2e-24	118
rs:WP_023505674	DNA topoisomerase I [uncultured archaeon A07HR60].	22.58	589	365	18	7	541	8	559	2e-24	119
rs:WP_034018007	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	26.21	412	263	10	200	573	1	409	2e-24	117
rs:WP_002823696	DNA topoisomerase [Oenococcus oeni].	28.69	373	228	12	213	563	1	357	2e-24	117
rs:WP_016241259	DNA topoisomerase III [Escherichia coli].	29.22	373	228	11	189	531	48	414	2e-24	118
rs:WP_016627781	DNA topoisomerase [Enterococcus faecium].	31.14	289	178	8	279	556	43	321	2e-24	116
tr:A0A090JUA7_METFO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.37	546	321	26	7	530	5	491	2e-24	118
rs:WP_011833511	DNA topoisomerase I [Methanocorpusculum labreanum].	24.95	541	342	19	7	532	4	495	2e-24	119
tr:T1DTV0_9PORP	SubName: Full=DNA topoisomerase III, Bacteroidales-type {ECO:0000313|EMBL:GAD06024.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAD06024.1};	26.67	465	277	17	56	485	2	437	2e-24	116
rs:WP_031868977	DNA topoisomerase III, partial [Staphylococcus aureus].	27.41	332	209	11	7	334	5	308	2e-24	114
rs:WP_038587908	DNA topoisomerase I [Corynebacterium imitans].	25.78	578	333	22	5	544	11	530	2e-24	119
rs:WP_036171533	DNA topoisomerase I [Lysobacter dokdonensis].	25.34	592	340	21	7	563	6	530	2e-24	118
rs:WP_014406759	DNA topoisomerase I [Methanocella conradii].	25.73	517	322	18	34	539	52	517	2e-24	118
rs:WP_013180152	DNA topoisomerase I [Methanococcus voltae].	26.55	550	341	18	7	539	5	508	2e-24	118
rs:WP_033603300	DNA topoisomerase, partial [Enterococcus faecalis].	26.89	409	277	11	147	544	9	406	2e-24	116
rs:WP_009886426	DNA topoisomerase I [Ferroplasma acidarmanus].	25.36	556	352	19	18	563	7	509	2e-24	118
rs:WP_047137101	DNA topoisomerase I [Luteimonas sp. FCS-9].	26.05	595	332	20	7	563	6	530	3e-24	118
rs:WP_029658328	DNA topoisomerase, partial [Enterococcus faecalis].	26.30	403	279	9	151	544	1	394	3e-24	117
rs:WP_002346508	DNA topoisomerase III [Streptococcus suis].	27.37	391	262	10	165	544	8	387	3e-24	117
rs:WP_043315150	hypothetical protein [Pseudomonas sp. PI1].	35.84	173	103	4	8	180	5	169	3e-24	110
rs:WP_006363114	DNA topoisomerase [Slackia exigua].	23.32	609	382	22	35	607	64	623	3e-24	118
rs:WP_002355348	toprim domain protein, partial [Enterococcus faecium].	30.03	343	218	11	5	339	3	331	3e-24	114
rs:WP_035594534	DNA topoisomerase I [Hyphomonas polymorpha].	26.55	531	306	21	7	505	4	482	3e-24	118
rs:WP_004323380	MULTISPECIES: DNA topoisomerase III [Bacteroides].	23.14	631	393	20	4	591	1	582	3e-24	117
rs:WP_014027476	DNA topoisomerase I [Pyrolobus fumarii].	25.21	607	389	21	7	594	15	575	3e-24	117
gpu:CP009530_812	DNA topoisomerase I [Methanosarcina barkeri 227]	25.18	568	358	19	48	601	55	569	3e-24	118
rs:WP_038452680	DNA topoisomerase I [Campylobacter fetus].	27.46	437	277	13	89	505	59	475	3e-24	117
rs:WP_035147818	DNA topoisomerase I [Campylobacter fetus].	27.46	437	277	13	89	505	59	475	3e-24	117
rs:WP_012659505	DNA topoisomerase I [Halorubrum lacusprofundi].	23.00	574	353	17	7	532	8	540	3e-24	118
rs:WP_012901076	DNA topoisomerase I [Methanocella paludicola].	25.46	538	337	19	17	539	11	499	3e-24	117
tr:E1YRP3_9PORP	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFK63720.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFK63720.1};	26.18	317	224	6	278	591	39	348	3e-24	116
sp:TOP1_THEAC	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.88	619	379	26	1	593	1	559	3e-24	117
tr:R9MBF0_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOS68163.1};	26.32	418	246	15	147	539	6	386	3e-24	117
rs:WP_007108079	DNA topoisomerase I [Natrinema altunense].	24.80	508	341	17	7	498	4	486	3e-24	118
rs:WP_020971805	DNA topoisomerase I [Helicobacter pylori].	27.78	450	259	15	89	505	59	475	3e-24	117
rs:WP_011731723	DNA topoisomerase I [Campylobacter fetus].	27.46	437	277	13	89	505	59	475	3e-24	117
tr:G0QAX5_NANSJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.45	544	345	21	5	531	3	497	3e-24	117
rs:WP_024623473	DNA topoisomerase, partial [Streptococcus pyogenes].	28.32	346	189	12	213	539	3	308	3e-24	114
rs:WP_019618173	hypothetical protein [Pseudoclavibacter faecalis].	25.22	559	316	20	7	505	6	522	3e-24	118
rs:WP_008848835	DNA topoisomerase I [Halorubrum kocurii].	23.05	577	350	19	7	532	8	541	3e-24	118
rs:WP_006801926	DNA topoisomerase I [Helicobacter winghamensis].	25.24	531	340	14	90	599	60	554	4e-24	117
rs:WP_024635937	DNA topoisomerase [Enterococcus faecium].	31.14	289	178	8	279	556	43	321	4e-24	115
rs:WP_008685770	DNA topoisomerase I [Desulfovibrio sp. 3_1_syn3].	27.42	423	258	15	107	504	72	470	4e-24	117
rs:WP_002330416	hypothetical protein [Enterococcus faecium].	31.14	289	178	8	279	556	43	321	4e-24	115
rs:WP_040367708	DNA topoisomerase, partial [Enterococcus italicus].	25.84	418	292	9	136	544	19	427	4e-24	117
rs:WP_002352835	DNA topoisomerase, partial [Enterococcus faecium].	27.06	340	224	9	165	491	24	352	4e-24	114
rs:WP_019338924	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.68	588	343	20	7	563	6	530	4e-24	117
rs:WP_002314343	DNA topoisomerase [Enterococcus faecium].	31.14	289	178	8	279	556	43	321	4e-24	115
rs:WP_022215638	DNA topoisomerase [Blautia sp. CAG:237].	29.36	344	194	13	253	554	30	366	4e-24	115
rs:WP_021725319	DNA topoisomerase I [Olsenella profusa].	24.68	547	340	22	65	588	109	606	4e-24	117
rs:WP_044960508	DNA topoisomerase III [Faecalibacterium prausnitzii].	27.22	360	222	11	203	547	20	354	4e-24	116
rs:WP_032129673	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.68	588	343	20	7	563	6	530	4e-24	117
rs:WP_021791689	hypothetical protein [Thermoplasmatales archaeon I-plasma].	25.16	612	370	22	1	588	1	548	4e-24	117
rs:WP_043272436	hypothetical protein [Pseudomonas sp. AAC].	35.84	173	103	4	8	180	5	169	4e-24	110
tr:L2JIY6_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.81	392	255	10	192	563	8	391	4e-24	116
rs:WP_033606902	DNA topoisomerase, partial [Enterococcus faecium].	25.84	418	292	9	136	544	19	427	4e-24	117
rs:WP_041064938	DNA topoisomerase I [Thiolapillus brandeum].	25.86	553	312	21	7	512	4	505	4e-24	117
tr:S9RZV6_9RHOB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.68	257	145	7	317	548	1	254	4e-24	116
rs:WP_005841655	DNA topoisomerase, partial [Bacteroides vulgatus].	24.12	398	282	9	200	591	15	398	5e-24	116
rs:WP_044325068	DNA topoisomerase III, partial [Pseudomonas amygdali].	32.06	287	163	8	282	540	20	302	5e-24	115
tr:W0JX63_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.26	548	368	18	7	539	4	508	5e-24	117
rs:WP_029657371	DNA topoisomerase, partial [Enterococcus faecalis].	31.45	248	154	8	5	245	3	241	5e-24	111
rs:WP_019595578	DNA topoisomerase I [Peptostreptococcus anaerobius].	24.40	627	380	23	7	607	6	564	5e-24	117
tr:D4RDK3_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.17	368	243	10	213	563	1	360	5e-24	116
tr:K1UE89_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC76530.1}; Flags: Fragment;	29.41	323	188	11	7	322	17	306	5e-24	113
rs:WP_005414607	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.68	588	343	20	7	563	6	530	5e-24	117
rs:WP_005411198	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.68	588	343	20	7	563	6	530	5e-24	117
rs:WP_021935290	DNA topoisomerase [Peptostreptococcus anaerobius CAG:621].	24.40	627	380	23	7	607	6	564	5e-24	117
gpu:CP009528_1551	DNA topoisomerase I [Methanosarcina barkeri MS]	25.18	568	358	19	48	601	55	569	5e-24	117
rs:WP_043640256	DNA topoisomerase I [Desulfovibrio sp. TomC].	27.63	438	270	15	91	505	58	471	5e-24	117
tr:A7LUK2_BACO1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.09	628	397	20	4	591	1	582	5e-24	116
rs:WP_023992619	DNA topoisomerase 1 [Methanobacterium sp. MB1].	26.25	541	328	25	7	530	5	491	6e-24	117
rs:WP_019550692	DNA topoisomerase I [Thermus scotoductus].	25.66	565	302	23	1	505	14	520	6e-24	117
rs:WP_012646645	DNA topoisomerase I [Geobacter daltonii].	26.50	532	310	18	7	505	6	489	6e-24	117
rs:WP_004312901	DNA topoisomerase, partial [Bacteroides xylanisolvens].	26.05	311	220	6	284	591	1	304	6e-24	114
rs:WP_042963560	DNA topoisomerase I [Campylobacter coli].	26.03	438	280	13	89	504	60	475	6e-24	117
rs:WP_016370883	DNA topoisomerase I, partial [Lactobacillus paracasei].	26.83	533	310	21	1	504	1	482	6e-24	116
rs:WP_033630599	DNA topoisomerase, partial [Enterococcus faecium].	25.60	418	293	9	136	544	19	427	6e-24	116
rs:WP_002884212	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	6e-24	117
rs:WP_019660785	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.68	588	343	20	7	563	6	530	6e-24	117
rs:WP_025477999	DNA topoisomerase [Enterococcus faecium].	31.14	289	178	8	279	556	43	321	6e-24	114
rs:WP_014648569	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.68	588	343	20	7	563	6	530	6e-24	117
tr:J9W7D3_LACBU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.65	409	264	12	213	603	1	391	6e-24	115
rs:WP_010481170	DNA topoisomerase I [[Pseudomonas] geniculata].	25.68	588	343	20	7	563	6	530	7e-24	117
rs:WP_005710553	DNA topoisomerase I [Lactobacillus rhamnosus].	26.37	531	315	20	1	504	1	482	7e-24	116
rs:WP_010214857	DNA topoisomerase III, partial [Pseudomonas syringae group genomosp. 3].	34.88	172	104	3	8	179	5	168	7e-24	109
rs:WP_002825508	DNA topoisomerase I [Campylobacter coli].	26.03	438	280	13	89	504	60	475	7e-24	116
rs:WP_002872293	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	7e-24	116
rs:WP_014659216	DNA topoisomerase I [Helicobacter cetorum].	27.38	442	271	14	89	505	59	475	7e-24	117
rs:WP_002376294	DNA topoisomerase [Enterococcus faecium].	31.14	289	178	8	279	556	43	321	7e-24	114
rs:WP_010715569	hypothetical protein [Enterococcus faecalis].	31.45	248	154	8	5	245	3	241	7e-24	111
rs:WP_042707682	DNA topoisomerase I [Methanobrevibacter wolinii].	26.23	549	324	23	7	532	5	495	7e-24	117
rs:WP_011022481	DNA topoisomerase I [Methanosarcina acetivorans].	24.47	523	337	15	81	589	79	557	7e-24	117
rs:WP_024404254	DNA topoisomerase I [Streptococcus suis].	25.10	526	309	17	7	504	18	486	7e-24	116
rs:WP_020445669	DNA topoisomerase I [Salinarchaeum sp. Harcht-Bsk1].	22.92	589	367	19	7	555	4	545	7e-24	117
rs:WP_042685532	DNA topoisomerase I [Methermicoccus shengliensis].	23.88	624	384	24	7	599	4	567	7e-24	116
tr:R8QQ81_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.88	373	237	10	201	554	12	371	7e-24	115
rs:WP_044766305	DNA topoisomerase I [Streptococcus suis].	25.10	526	308	17	7	504	18	485	7e-24	116
gpu:CP008874_633	DNA topoisomerase I [Halanaeroarchaeum sulfurireducens]	23.13	549	364	18	7	539	4	510	8e-24	117
rs:WP_021203233	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.68	588	343	20	7	563	6	530	8e-24	117
rs:WP_033714660	DNA topoisomerase III, partial [Bacillus cereus].	27.88	373	237	10	201	554	1	360	8e-24	115
rs:WP_016363891	DNA topoisomerase I, partial [Lactobacillus paracasei].	26.83	533	310	21	1	504	1	482	8e-24	116
rs:WP_032958266	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.68	588	343	20	7	563	6	530	8e-24	116
rs:WP_029656734	DNA topoisomerase, partial [Enterococcus faecalis].	31.47	251	156	8	5	248	3	244	8e-24	112
rs:WP_002351371	toprim domain protein, partial [Enterococcus faecium].	30.28	251	159	8	5	248	3	244	9e-24	111
rs:WP_034813314	DNA topoisomerase I [Hyphomonas sp. L-53-1-40].	26.88	532	303	22	7	505	4	482	9e-24	116
rs:WP_007994801	DNA topoisomerase I [Halorubrum arcis].	23.02	543	341	18	7	498	8	524	9e-24	116
rs:WP_027890873	DNA topoisomerase I [Megamonas hypermegale].	24.87	591	331	23	1	553	1	516	9e-24	116
rs:WP_042706517	DNA topoisomerase I [Methanomicrobium mobile].	24.34	493	319	16	48	532	48	494	9e-24	116
tr:K1U396_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC76693.1}; Flags: Fragment;	28.97	359	226	10	99	450	9	345	1e-23	112
rs:WP_022227777	DNA topoisomerase [Megamonas funiformis CAG:377].	24.75	590	333	23	1	553	1	516	1e-23	116
rs:WP_038855449	DNA topoisomerase I [Campylobacter coli].	25.97	439	281	13	89	505	60	476	1e-23	116
rs:WP_002894594	DNA topoisomerase I [Campylobacter jejuni].	25.57	442	279	14	89	505	60	476	1e-23	116
rs:WP_031825299	DNA topoisomerase III, partial [Staphylococcus aureus].	27.19	331	209	11	7	333	5	307	1e-23	112
tr:E6LIS5_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.74	389	267	9	165	544	8	387	1e-23	115
rs:WP_008163680	DNA topoisomerase I [Natronorubrum sulfidifaciens].	22.91	550	370	18	7	541	4	514	1e-23	116
rs:WP_002928190	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	1e-23	116
rs:WP_021033792	DNA topoisomerase I [Campylobacter coli].	25.57	442	279	14	89	505	60	476	1e-23	116
rs:WP_010714235	hypothetical protein [Enterococcus faecalis].	32.41	253	151	9	5	248	3	244	1e-23	112
rs:WP_029176280	DNA topoisomerase I [Streptococcus suis].	25.10	526	308	17	7	504	18	485	1e-23	116
rs:WP_012481370	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.51	588	344	20	7	563	6	530	1e-23	116
rs:WP_043034573	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.51	588	344	20	7	563	6	530	1e-23	116
rs:WP_025083276	DNA topoisomerase I [Lactobacillus fuchuensis].	25.05	535	318	19	1	504	1	483	1e-23	116
rs:WP_024400616	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	1e-23	116
rs:WP_008538386	DNA topoisomerase I [Megamonas funiformis].	24.75	590	333	23	1	553	1	516	1e-23	116
rs:WP_018999216	DNA topoisomerase I [Megamonas rupellensis].	24.75	590	333	23	1	553	1	516	1e-23	116
rs:WP_024383462	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	1e-23	116
rs:WP_023444285	hypothetical protein [Pseudomonas chloritidismutans].	27.69	437	263	13	86	495	48	458	1e-23	115
rs:WP_032590264	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	1e-23	116
rs:WP_044764051	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	1e-23	115
rs:WP_008267195	DNA topoisomerase I [Stenotrophomonas sp. SKA14].	25.68	588	343	20	7	563	6	530	1e-23	116
rs:WP_000681456	DNA topoisomerase I [Helicobacter pylori].	27.68	448	262	15	89	505	59	475	1e-23	116
tr:F3GEZ0_PSESJ	SubName: Full=Orf50 {ECO:0000313|EMBL:EGH45640.1}; Flags: Fragment;	25.98	358	247	10	4	356	1	345	1e-23	112
rs:WP_031921633	DNA topoisomerase III, partial [Staphylococcus aureus].	31.54	260	162	7	291	544	3	252	1e-23	113
rs:WP_043012938	DNA topoisomerase 1 [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	1e-23	115
rs:WP_002902895	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	1e-23	115
rs:WP_012775596	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	1e-23	115
rs:WP_002945497	DNA topoisomerase I [Campylobacter rectus].	27.98	436	276	14	89	505	59	475	1e-23	115
rs:WP_014038639	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.51	588	344	20	7	563	6	530	1e-23	116
rs:WP_002917004	DNA topoisomerase I, partial [Campylobacter jejuni].	24.23	520	324	17	7	505	6	476	1e-23	115
rs:WP_020675223	hypothetical protein [Geopsychrobacter electrodiphilus].	25.95	528	320	16	7	505	6	491	1e-23	116
sp:TOP1_CAMJE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.57	438	284	13	89	505	60	476	1e-23	115
rs:WP_024405688	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	1e-23	115
rs:WP_035168818	topoisomerase I, partial [Lactobacillus curieae].	29.17	312	187	9	5	301	3	295	1e-23	112
rs:WP_016385941	DNA topoisomerase I [Lactobacillus paracasei].	25.99	531	317	19	1	504	1	482	1e-23	115
rs:WP_044683261	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	1e-23	115
rs:WP_005713869	DNA topoisomerase I [Lactobacillus rhamnosus].	26.37	531	315	20	1	504	1	482	1e-23	115
rs:WP_012775128	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	1e-23	115
tr:A0A061P6L2_9BACL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAK11904.1};	33.77	228	134	7	5	225	3	220	1e-23	110
rs:WP_044475278	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	1e-23	115
rs:WP_007082332	DNA topoisomerase I [Rhodanobacter fulvus].	26.25	541	311	19	7	505	6	500	1e-23	116
rs:WP_032592152	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	1e-23	115
rs:WP_039848609	DNA topoisomerase I [Parabacteroides sp. D13].	24.73	461	308	12	97	544	39	473	1e-23	115
rs:WP_008005249	DNA topoisomerase I [Halorubrum lipolyticum].	22.92	576	352	19	7	532	8	541	1e-23	116
rs:WP_044979376	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	1e-23	115
rs:WP_017355382	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.46	593	338	21	7	563	6	530	1e-23	115
rs:WP_003598643	MULTISPECIES: DNA topoisomerase I [Lactobacillus casei group].	25.99	531	317	19	1	504	1	482	1e-23	115
rs:WP_003565415	MULTISPECIES: DNA topoisomerase I [Lactobacillus casei group].	25.99	531	317	19	1	504	1	482	1e-23	115
rs:WP_016371159	DNA topoisomerase I [Lactobacillus paracasei].	25.99	531	317	19	1	504	1	482	1e-23	115
rs:WP_045136213	DNA topoisomerase I [Lactobacillus paracasei].	25.99	531	317	19	1	504	1	482	1e-23	115
rs:WP_042853364	DNA topoisomerase III, partial [Staphylococcus aureus].	31.54	260	162	7	291	544	3	252	1e-23	113
tr:A0A011P1L8_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.39	449	283	12	107	519	13	445	1e-23	114
rs:WP_011177548	DNA topoisomerase I [Picrophilus torridus].	23.50	549	357	17	3	540	2	498	1e-23	115
rs:WP_012491591	MULTISPECIES: DNA topoisomerase I [Lactobacillus casei group].	25.99	531	317	19	1	504	1	482	1e-23	115
rs:WP_003602230	DNA topoisomerase I [Lactobacillus casei].	25.99	531	317	19	1	504	1	482	1e-23	115
rs:WP_032511243	DNA topoisomerase I [Streptococcus suis].	25.10	526	308	17	7	504	18	485	2e-23	115
rs:WP_016368026	DNA topoisomerase I [Lactobacillus paracasei].	25.99	531	317	19	1	504	1	482	2e-23	115
rs:WP_008515661	DNA topoisomerase I, archaeal [Methanobacterium sp. Maddingley MBC34].	25.36	548	324	25	7	530	5	491	2e-23	115
rs:WP_004049062	DNA topoisomerase I [Halorubrum saccharovorum].	22.78	575	353	18	7	532	8	540	2e-23	115
rs:WP_029658009	DNA topoisomerase, partial [Enterococcus faecalis].	30.98	255	160	8	1	248	1	246	2e-23	112
rs:WP_029657249	MULTISPECIES: DNA topoisomerase, partial [Enterococcus].	29.67	337	216	11	5	333	3	326	2e-23	112
rs:WP_002844064	DNA topoisomerase I [Peptostreptococcus anaerobius].	24.40	627	380	23	7	607	6	564	2e-23	115
rs:WP_007739277	DNA topoisomerase I [Halococcus thailandensis].	23.77	551	362	20	7	541	4	512	2e-23	115
rs:WP_044688674	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	2e-23	115
rs:WP_006191226	DNA topoisomerase I [Selenomonas sputigena].	27.13	575	318	25	5	553	117	616	2e-23	115
rs:WP_034605787	DNA topoisomerase I [Desulfovibrio desulfuricans].	27.23	426	256	16	107	505	76	474	2e-23	115
rs:WP_018297915	DNA topoisomerase I [Corynebacterium lubricantis].	25.36	556	321	21	2	505	7	520	2e-23	115
rs:WP_002322390	DNA topoisomerase, partial [Enterococcus faecium].	25.85	441	306	12	116	544	10	441	2e-23	114
rs:WP_045697622	DNA topoisomerase I [Hyphomonas sp. BRH_c22].	26.55	531	306	21	7	505	4	482	2e-23	115
rs:WP_002322285	DNA topoisomerase, partial [Enterococcus faecium].	25.85	441	306	12	116	544	9	440	2e-23	114
rs:WP_029943206	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	2e-23	115
rs:WP_024394027	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	2e-23	115
rs:WP_008002399	DNA topoisomerase I [Halorubrum aidingense].	23.09	576	351	18	7	532	8	541	2e-23	115
rs:WP_011839553	DNA topoisomerase I [Staphylothermus marinus].	23.85	587	371	23	6	566	56	592	2e-23	115
rs:WP_002874307	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	2e-23	115
rs:WP_002409429	toprim domain protein, partial [Enterococcus faecalis].	30.28	251	159	7	5	248	3	244	2e-23	110
rs:WP_002899161	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	2e-23	115
rs:WP_045625031	DNA topoisomerase I [Lactobacillus paracasei].	25.99	531	317	19	1	504	1	482	2e-23	115
rs:WP_024417185	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	2e-23	115
rs:WP_040966555	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	2e-23	115
rs:WP_014149842	DNA topoisomerase I [Methylomicrobium alcaliphilum].	25.92	544	304	19	7	505	6	495	2e-23	115
tr:C9CGT7_ENTFC	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEV43808.1}; Flags: Fragment;	32.00	250	153	8	5	247	4	243	2e-23	110
rs:WP_002878738	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	2e-23	115
rs:WP_035552266	DNA topoisomerase I [Hyphomonas atlantica].	26.65	529	308	21	7	505	4	482	2e-23	115
rs:WP_044778602	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	2e-23	115
rs:WP_044635092	DNA topoisomerase, partial [Treponema phagedenis].	30.48	292	160	9	266	539	27	293	2e-23	112
rs:WP_000681510	DNA topoisomerase I [Helicobacter pylori].	28.44	450	256	15	89	505	59	475	2e-23	115
rs:WP_002918791	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	2e-23	115
rs:WP_033795207	DNA topoisomerase, partial [Enterococcus faecium].	32.00	250	153	8	5	247	3	242	2e-23	110
rs:WP_002869687	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	2e-23	115
rs:WP_002867521	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	2e-23	115
rs:WP_018581804	DNA topoisomerase I [Corynebacterium pilosum].	26.13	555	318	22	2	505	7	520	2e-23	115
rs:WP_004816326	DNA topoisomerase, partial [Anaerococcus hydrogenalis].	26.72	348	231	10	266	604	35	367	2e-23	112
gp:CP008854_359	DNA topoisomerase III [Bacillus anthracis]	31.90	232	140	6	5	234	4	219	2e-23	110
rs:WP_015646822	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	2e-23	115
rs:WP_032575310	DNA topoisomerase I [Bacteroides fragilis].	25.89	448	299	12	107	544	49	473	2e-23	115
tr:A0A0B8NL35_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.17	312	190	11	56	350	2	299	2e-23	111
rs:WP_044278477	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	2e-23	115
rs:WP_044670821	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	2e-23	115
rs:WP_038231947	DNA topoisomerase, partial [Xylella fastidiosa].	27.70	343	221	10	8	336	5	334	2e-23	111
rs:WP_002873255	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	2e-23	115
rs:WP_002870465	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	2e-23	115
rs:WP_024407141	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	2e-23	115
rs:WP_014558129	DNA topoisomerase III [Fervidicoccus fontis].	24.47	617	376	24	5	589	14	572	2e-23	115
rs:WP_021639559	DNA topoisomerase, partial [Clostridium sp. KLE 1755].	29.68	283	175	9	282	550	11	283	2e-23	113
rs:WP_002829326	DNA topoisomerase I [Campylobacter coli].	25.11	442	281	14	89	505	60	476	2e-23	115
rs:WP_044765802	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	2e-23	115
rs:WP_029171748	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	2e-23	115
rs:WP_011498278	DNA topoisomerase I [Methanococcoides burtonii].	23.63	546	333	16	41	562	46	531	2e-23	115
rs:WP_044768045	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	2e-23	115
rs:WP_023499727	Topoisomerase IA [uncultured archaeon A07HB70].	23.02	556	363	18	7	541	4	515	2e-23	115
rs:WP_036889132	DNA topoisomerase I, partial [Prevotella enoeca].	29.18	329	200	14	213	531	1	306	2e-23	111
rs:WP_032586403	DNA topoisomerase I [Campylobacter jejuni].	25.34	438	285	13	89	505	60	476	2e-23	115
rs:WP_031834058	DNA topoisomerase III, partial [Staphylococcus aureus].	30.93	333	196	12	5	322	3	316	2e-23	111
rs:WP_039635672	hypothetical protein [Clostridium argentinense].	24.14	497	306	17	135	580	24	500	2e-23	114
rs:WP_044769796	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	2e-23	115
rs:WP_038230219	DNA topoisomerase, partial [Xylella fastidiosa].	27.70	343	221	10	8	336	5	334	3e-23	111
rs:WP_002864986	DNA topoisomerase I [Campylobacter jejuni].	25.34	438	285	13	89	505	60	476	3e-23	115
rs:WP_029751772	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	115
gp:CP007493_220	DNA topoisomerase I [Thermofilum carboxyditrophus 1505]	25.36	548	340	20	6	530	6	507	3e-23	114
rs:WP_010733726	MULTISPECIES: DNA topoisomerase III, partial [Enterococcus].	25.55	407	285	10	147	544	2	399	3e-23	113
rs:WP_024385241	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	114
rs:WP_024419473	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	114
rs:WP_044771230	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	114
rs:WP_024387763	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	114
rs:WP_005688022	DNA topoisomerase I [Lactobacillus rhamnosus].	26.18	531	316	20	1	504	1	482	3e-23	114
rs:WP_044781401	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	114
rs:WP_004195696	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	114
rs:WP_024394484	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	114
rs:WP_009618233	DNA topoisomerase III [Pseudomonas sp. M1].	35.26	173	104	4	8	180	5	169	3e-23	108
rs:WP_012955193	DNA topoisomerase I [Methanobrevibacter ruminantium].	24.86	547	333	20	7	532	5	494	3e-23	115
rs:WP_024408846	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	114
rs:WP_044758837	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	114
rs:WP_032591081	DNA topoisomerase I [Campylobacter jejuni].	25.34	438	285	13	89	505	60	476	3e-23	114
rs:WP_000681414	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	17	89	505	59	475	3e-23	114
rs:WP_023370336	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	114
rs:WP_035396024	hypothetical protein, partial [Chloroflexi bacterium SCGC AB-629-P13].	25.00	648	371	26	7	607	6	585	3e-23	114
rs:WP_002877023	DNA topoisomerase I [Campylobacter jejuni].	25.34	438	285	13	89	505	60	476	3e-23	114
rs:WP_042630907	DNA topoisomerase III, partial [Escherichia coli].	30.92	249	151	5	315	543	5	252	3e-23	113
rs:WP_044771417	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	114
rs:WP_044667700	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	114
rs:WP_002305037	type I topoisomerase, partial [Enterococcus faecium].	32.40	250	152	8	5	247	3	242	3e-23	109
rs:WP_044762088	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	114
rs:WP_002358513	toprim domain protein, partial [Enterococcus faecium].	32.00	250	153	8	5	247	3	242	3e-23	109
rs:WP_024409355	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	114
rs:WP_008026309	DNA topoisomerase III [Bacteroides xylanisolvens].	22.98	631	394	20	4	591	1	582	3e-23	114
rs:WP_004215386	DNA topoisomerase I [Natrialba magadii].	22.65	565	368	18	7	541	4	529	3e-23	114
tr:A0A0A6SU61_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.92	249	151	5	315	543	12	259	3e-23	113
rs:WP_027081690	DNA topoisomerase I [Lysobacter sp. URHA0019].	25.00	592	342	21	7	563	6	530	3e-23	114
rs:WP_044762879	DNA topoisomerase I [Streptococcus suis].	24.71	526	310	17	7	504	18	485	3e-23	114
rs:WP_024410540	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	3e-23	114
tr:M3NPB4_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.38	451	255	16	89	505	59	475	4e-23	114
rs:WP_002841473	DNA topoisomerase I [Campylobacter coli].	25.11	442	281	14	89	505	60	476	4e-23	114
rs:WP_044689880	DNA topoisomerase I [Streptococcus suis].	24.95	521	315	17	7	504	18	485	4e-23	114
rs:WP_002936490	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	4e-23	114
rs:WP_044755138	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	4e-23	114
rs:WP_038814824	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	4e-23	114
rs:WP_024397127	DNA topoisomerase I [Streptococcus suis].	24.71	526	310	17	7	504	18	485	4e-23	114
rs:WP_025346247	DNA topoisomerase I [Sulfurospirillum multivorans].	25.38	520	318	18	7	505	5	475	4e-23	114
rs:WP_029750153	DNA topoisomerase, partial [Streptococcus agalactiae].	30.90	301	177	10	254	539	3	287	4e-23	111
rs:WP_032126693	DNA topoisomerase I [Piscirickettsia salmonis].	25.09	538	315	17	7	505	6	494	4e-23	114
rs:WP_029588602	DNA topoisomerase I [Campylobacter jejuni].	24.23	520	324	18	7	505	6	476	4e-23	114
rs:WP_044769733	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	4e-23	114
rs:WP_002362367	DNA topoisomerase, partial [Enterococcus faecium].	27.22	338	222	10	165	489	30	356	4e-23	111
tr:E4IKL2_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.85	441	306	12	116	544	10	441	4e-23	114
rs:WP_033642401	DNA topoisomerase, partial [Enterococcus faecium].	25.85	441	306	12	116	544	1	432	4e-23	114
rs:WP_024388699	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	4e-23	114
rs:WP_000681438	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	4e-23	114
tr:A0A0B8PFG7_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.41	332	200	11	107	418	43	353	4e-23	111
rs:WP_024392292	DNA topoisomerase I [Streptococcus suis].	24.71	526	310	17	7	504	18	485	4e-23	114
tr:E2XSJ8_PSEFL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFQ63312.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFQ63312.1};	36.78	174	99	3	375	539	6	177	4e-23	110
rs:WP_013245718	DNA topoisomerase I [Lactobacillus casei].	25.99	531	317	19	1	504	1	482	4e-23	114
tr:E4ICB9_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.85	441	306	12	116	544	10	441	4e-23	114
rs:WP_013730365	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	4e-23	114
rs:WP_029173296	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	4e-23	114
rs:WP_014636962	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	4e-23	114
tr:E7PGW7_PSESG	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFW87203.1}; Flags: Fragment;	34.57	188	108	5	41	224	1	177	4e-23	107
rs:WP_002888820	DNA topoisomerase I [Campylobacter jejuni].	25.34	438	285	13	89	505	60	476	4e-23	114
rs:WP_038851041	DNA topoisomerase I [Campylobacter coli].	25.11	438	286	13	89	505	60	476	4e-23	114
rs:WP_038846354	DNA topoisomerase I [Campylobacter coli].	25.11	438	286	13	89	505	60	476	4e-23	114
rs:WP_022370128	DNA topoisomerase type IA central domain protein [Eggerthella sp. CAG:368].	23.70	557	354	18	66	602	108	613	4e-23	114
rs:WP_002809711	DNA topoisomerase I [Campylobacter coli].	25.11	438	286	13	89	505	60	476	4e-23	114
rs:WP_000681500	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	4e-23	114
rs:WP_002908846	DNA topoisomerase I [Campylobacter jejuni].	25.57	438	284	13	89	505	60	476	4e-23	114
rs:WP_033743595	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	4e-23	114
rs:WP_044686750	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	4e-23	114
rs:WP_016544013	DNA topoisomerase I [Leptospira wolffii].	24.57	521	319	18	7	505	5	473	4e-23	114
rs:WP_033645481	DNA topoisomerase, partial [Enterococcus faecium].	25.85	441	306	12	116	544	1	432	5e-23	114
rs:WP_002913205	DNA topoisomerase I [Campylobacter jejuni].	25.74	439	282	13	89	505	60	476	5e-23	114
rs:WP_005823252	DNA topoisomerase I [Bacteroides fragilis].	25.67	448	300	12	107	544	49	473	5e-23	114
rs:WP_000681446	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	5e-23	114
rs:WP_044684533	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	5e-23	114
rs:WP_046983426	DNA topoisomerase I [Thermomonas brevis].	25.51	588	344	20	7	563	6	530	5e-23	114
rs:WP_002789823	DNA topoisomerase I [Campylobacter coli].	25.11	442	281	14	89	505	60	476	5e-23	114
rs:WP_002842632	DNA topoisomerase I [Campylobacter coli].	25.11	442	281	14	89	505	60	476	5e-23	114
rs:WP_002911147	DNA topoisomerase I [Campylobacter jejuni].	25.11	438	286	13	89	505	60	476	5e-23	114
rs:WP_002803036	DNA topoisomerase I [Campylobacter coli].	25.11	442	281	14	89	505	60	476	5e-23	114
rs:WP_023048857	hypothetical protein, partial [Pseudomonas putida].	34.55	165	100	4	3	167	11	167	5e-23	107
rs:WP_023384164	DNA topoisomerase I [Campylobacter fetus].	27.23	437	278	13	89	505	59	475	5e-23	114
rs:WP_034738529	DNA topoisomerase I [Hyphomonas chukchiensis].	26.37	531	307	21	7	505	4	482	5e-23	114
rs:WP_000681435	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	5e-23	114
rs:WP_000681433	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	5e-23	114
rs:WP_011822082	DNA topoisomerase I [Hyperthermus butylicus].	24.35	616	391	20	5	595	14	579	5e-23	114
rs:WP_040152275	DNA topoisomerase III, partial [Xanthomonas citri].	36.63	172	101	4	7	178	4	167	5e-23	107
rs:WP_024381859	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	5e-23	114
rs:WP_039361773	DNA topoisomerase I [Campylobacter fetus].	27.23	437	278	13	89	505	59	475	5e-23	114
rs:WP_041958543	DNA topoisomerase I [Sulfurospirillum arsenophilum].	25.58	520	317	18	7	505	5	475	5e-23	114
rs:WP_029658570	DNA topoisomerase, partial [Enterococcus faecalis].	25.81	403	281	9	151	544	1	394	5e-23	113
rs:WP_000681522	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	5e-23	114
rs:WP_000681405	DNA topoisomerase I [Helicobacter pylori].	28.22	450	257	17	89	505	59	475	5e-23	114
rs:WP_001961309	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	5e-23	114
rs:WP_032976671	DNA topoisomerase I [Stenotrophomonas sp. RIT309].	25.47	589	344	20	7	563	6	531	5e-23	114
rs:WP_027305561	DNA topoisomerase I [Campylobacter cuniculorum].	24.76	517	325	17	7	505	6	476	5e-23	114
rs:WP_002564088	MULTISPECIES: DNA topoisomerase I [Atopobium].	24.35	542	335	19	65	584	109	597	5e-23	114
rs:WP_005805288	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.67	448	300	12	107	544	49	473	5e-23	114
rs:WP_025879065	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.47	589	344	20	7	563	6	531	5e-23	114
rs:WP_033832335	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.47	589	344	20	7	563	6	531	5e-23	114
rs:WP_000681506	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	5e-23	114
rs:WP_024398072	DNA topoisomerase I [Streptococcus suis].	24.95	521	315	17	7	504	18	485	5e-23	114
rs:WP_004030988	DNA topoisomerase I [Methanobacterium formicicum].	26.28	548	319	28	7	530	5	491	5e-23	114
rs:WP_001972196	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	5e-23	114
rs:WP_044754361	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	5e-23	114
tr:S5W9P8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.18	369	242	11	47	406	2	356	5e-23	110
rs:WP_023845950	DNA topoisomerase I, archaeal [Methanolobus tindarius].	23.75	598	378	19	7	583	10	550	5e-23	114
rs:WP_033573047	DNA topoisomerase I [Lactobacillus rhamnosus].	25.80	531	318	19	1	504	1	482	5e-23	114
rs:WP_013898006	DNA topoisomerase I [Methanosalsum zhilinae].	25.59	547	333	20	7	532	4	497	5e-23	114
rs:WP_044775437	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	5e-23	114
rs:WP_029180300	DNA topoisomerase I [Streptococcus suis].	24.62	532	303	18	7	504	18	485	5e-23	114
rs:WP_001957767	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	5e-23	114
tr:M3LLJ8_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.38	451	255	16	89	505	59	475	5e-23	114
rs:WP_002937473	DNA topoisomerase I [Campylobacter jejuni].	25.34	438	285	13	89	505	60	476	5e-23	114
rs:WP_002856309	MULTISPECIES: DNA topoisomerase I [Campylobacter].	25.11	438	286	13	89	505	60	476	5e-23	114
tr:J6Y116_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJY32199.1}; Flags: Fragment;	32.00	250	153	8	5	247	3	242	5e-23	109
rs:WP_014758637	MULTISPECIES: DNA topoisomerase I [Thermoanaerobacterium].	25.63	632	351	25	7	598	6	558	6e-23	114
rs:WP_006036001	DNA topoisomerase I [Rickettsiella grylli].	26.59	549	303	18	7	505	6	504	6e-23	114
rs:WP_033595303	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	6e-23	114
rs:WP_010488381	MULTISPECIES: DNA topoisomerase I [Lactobacillus casei group].	25.61	531	319	19	1	504	1	482	6e-23	114
rs:WP_037619942	DNA topoisomerase, partial [Streptococcus parauberis].	29.88	251	160	7	5	248	3	244	6e-23	108
rs:WP_039638996	DNA topoisomerase I [Lactobacillus sp. FMNP02].	25.61	531	319	19	1	504	1	482	6e-23	114
rs:WP_024390017	DNA topoisomerase I [Streptococcus suis].	24.86	527	308	18	7	504	18	485	6e-23	114
rs:WP_009644989	DNA topoisomerase I [Selenomonas sp. CM52].	26.96	575	319	25	5	553	112	611	6e-23	114
rs:WP_000681507	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	6e-23	114
tr:F0FDB0_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.42	520	318	17	7	504	19	485	6e-23	113
rs:WP_000681508	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	6e-23	114
rs:WP_044776982	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	6e-23	113
rs:WP_005419627	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.51	588	344	20	7	563	6	530	6e-23	114
rs:WP_034825430	DNA topoisomerase I [Hyphomonas sp. T16B2].	26.47	529	309	21	7	505	4	482	6e-23	114
rs:WP_000681447	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	7e-23	114
rs:WP_015763957	DNA topoisomerase I [Halomicrobium mukohataei].	23.00	626	398	22	7	602	4	575	7e-23	114
rs:WP_033622086	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	7e-23	114
rs:WP_002208130	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	7e-23	114
rs:WP_032914840	DNA topoisomerase I [Streptococcus sanguinis].	24.42	520	318	17	7	504	16	482	7e-23	113
rs:WP_044759764	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	7e-23	113
rs:WP_038841321	DNA topoisomerase I [Campylobacter coli].	25.74	439	282	13	89	505	60	476	7e-23	113
rs:WP_033655636	DNA topoisomerase, partial [Enterococcus faecium].	29.88	251	160	8	5	248	3	244	7e-23	110
rs:WP_000681516	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	7e-23	113
rs:WP_002826940	DNA topoisomerase I [Campylobacter coli].	25.34	438	285	13	89	505	60	476	7e-23	113
rs:WP_001931094	DNA topoisomerase I [Helicobacter pylori].	28.29	449	258	17	89	505	59	475	7e-23	113
rs:WP_029659095	DNA topoisomerase, partial [Enterococcus faecalis].	26.05	403	280	9	151	544	1	394	7e-23	113
tr:A0A066ZGK8_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.48	389	268	9	165	544	22	401	7e-23	113
rs:WP_011139337	DNA topoisomerase I [Wolinella succinogenes].	24.71	526	314	19	7	505	5	475	7e-23	113
rs:WP_043027054	DNA topoisomerase I [Streptococcus suis].	24.62	532	303	18	7	504	18	485	7e-23	113
rs:WP_014638935	DNA topoisomerase I [Streptococcus suis].	24.62	532	303	18	7	504	18	485	7e-23	113
rs:WP_001943348	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	7e-23	113
rs:WP_000681514	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	8e-23	113
rs:WP_044693788	DNA topoisomerase I, partial [Streptococcus suis].	24.71	526	310	17	7	504	18	485	8e-23	113
rs:WP_012512224	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.34	588	345	20	7	563	6	530	8e-23	113
rs:WP_033781617	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	8e-23	113
rs:WP_044779754	DNA topoisomerase I [Campylobacter jejuni].	25.34	438	285	13	89	505	60	476	8e-23	113
rs:WP_005715619	DNA topoisomerase I [Lactobacillus rhamnosus].	25.80	531	318	19	1	504	1	482	8e-23	113
rs:WP_042964624	DNA topoisomerase I [Campylobacter coli].	25.74	439	282	13	89	505	60	476	8e-23	113
tr:R3FTE9_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.48	389	268	9	165	544	8	387	8e-23	112
tr:C3DEJ6_BACTS	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EEM43623.1};	31.62	234	142	6	3	234	2	219	8e-23	108
rs:WP_008153390	hypothetical protein, partial [Parabacteroides johnsonii].	27.91	258	179	5	276	531	84	336	8e-23	110
rs:WP_035537897	DNA topoisomerase I [Hyphomonas oceanitis].	26.18	531	308	21	7	505	4	482	8e-23	113
rs:WP_002335445	hypothetical protein [Enterococcus faecalis].	29.88	251	160	8	5	248	3	244	8e-23	109
rs:WP_039943978	DNA topoisomerase, partial [Treponema phagedenis].	30.48	292	160	9	266	539	88	354	8e-23	111
tr:A0A0B7H388_TREPH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.48	292	160	9	266	539	115	381	8e-23	111
rs:WP_022948084	DNA topoisomerase I [Methylohalobius crimeensis].	25.51	541	309	18	7	505	6	494	8e-23	113
rs:WP_033745323	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	8e-23	113
rs:WP_011922475	DNA topoisomerase I [Streptococcus suis].	24.81	520	318	15	7	504	33	501	9e-23	113
rs:WP_002892042	DNA topoisomerase I [Campylobacter jejuni].	25.11	438	286	13	89	505	60	476	9e-23	113
rs:WP_014660517	DNA topoisomerase I [Helicobacter cetorum].	27.90	448	261	15	89	505	59	475	9e-23	113
rs:WP_015409059	DNA topoisomerase I [Natronomonas moolapensis].	23.58	547	366	19	7	541	4	510	9e-23	113
rs:WP_029178045	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	9e-23	113
tr:S4E3Z4_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EPI14111.1};	29.88	251	160	7	5	248	3	244	9e-23	108
rs:WP_039085178	DNA topoisomerase I [Helicobacter pylori].	28.29	449	258	16	89	505	59	475	9e-23	113
rs:WP_027327234	DNA topoisomerase I [Helicobacter pametensis].	27.73	440	272	13	89	505	59	475	9e-23	113
rs:WP_032963408	DNA topoisomerase I [Lactobacillus rhamnosus].	25.80	531	318	19	1	504	1	482	9e-23	113
rs:WP_032582168	DNA topoisomerase I [Campylobacter jejuni].	25.11	438	286	13	89	505	60	476	9e-23	113
rs:WP_011990971	DNA topoisomerase I [Campylobacter jejuni].	25.34	438	285	13	89	505	60	476	9e-23	113
rs:WP_046835605	hypothetical protein, partial [Pseudomonas amygdali].	32.26	217	132	5	40	252	3	208	1e-22	107
rs:WP_027836252	DNA topoisomerase I [Mastigocoleus testarum].	26.47	529	309	21	7	505	4	482	1e-22	113
rs:WP_024390904	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	1e-22	113
rs:WP_002882239	DNA topoisomerase I [Campylobacter jejuni].	25.11	438	286	13	89	505	60	476	1e-22	113
rs:WP_008427267	DNA topoisomerase I [Natronococcus jeotgali].	22.93	567	365	20	7	541	4	530	1e-22	113
rs:WP_023916231	DNA topoisomerase 1 [Streptococcus sanguinis].	24.81	520	316	17	7	504	16	482	1e-22	113
rs:WP_044953325	DNA topoisomerase III [Faecalibacterium prausnitzii].	25.37	469	286	18	145	590	4	431	1e-22	112
rs:WP_044794031	DNA topoisomerase I [Campylobacter jejuni].	25.34	438	285	13	89	505	60	476	1e-22	113
rs:WP_002352634	toprim domain protein, partial [Enterococcus faecium].	31.60	250	154	8	5	247	3	242	1e-22	108
rs:WP_033774513	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	1e-22	113
rs:WP_013638549	DNA topoisomerase I [Desulfurobacterium thermolithotrophum].	23.95	572	349	19	1	553	1	505	1e-22	113
rs:WP_043949226	DNA topoisomerase I [Candidatus Phaeomarinobacter ectocarpi].	26.76	553	301	25	7	510	6	503	1e-22	113
rs:WP_011322338	DNA topoisomerase I [Natronomonas pharaonis].	22.99	548	368	18	7	541	4	510	1e-22	113
tr:U3N9M1_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.68	283	175	9	282	550	15	287	1e-22	111
rs:WP_045411980	DNA topoisomerase I [Thermoanaerobacterium saccharolyticum].	24.84	632	356	24	7	598	6	558	1e-22	113
tr:A0A0B7GQ73_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	629	379	21	7	607	16	570	1e-22	113
rs:WP_038401936	DNA topoisomerase I [Campylobacter jejuni].	25.46	436	287	13	89	505	60	476	1e-22	113
rs:WP_041877706	DNA topoisomerase III, partial [Verrucomicrobia bacterium SCGC AAA164-O14].	30.82	292	173	9	283	554	24	306	1e-22	112
rs:WP_032910423	DNA topoisomerase I [Streptococcus sanguinis].	23.53	629	379	21	7	607	16	570	1e-22	113
rs:WP_042832014	DNA topoisomerase III, partial [Xanthomonas citri].	36.47	170	100	4	7	176	4	165	1e-22	105
rs:WP_012676889	DNA topoisomerase I [Persephonella marina].	24.47	564	350	16	7	561	10	506	1e-22	112
rs:WP_013617089	DNA topoisomerase III [Bacteroides salanitronis].	23.62	580	352	20	5	550	4	526	1e-22	112
rs:WP_032913392	DNA topoisomerase I [Streptococcus sanguinis].	23.53	629	379	21	7	607	16	570	1e-22	113
rs:WP_032912913	DNA topoisomerase I [Streptococcus sanguinis].	23.53	629	379	21	7	607	16	570	1e-22	113
gpu:CP011403_722	DNA topoisomerase I [Lactobacillus salivarius str. Ren]	27.65	434	272	15	93	504	36	449	1e-22	112
rs:WP_000557252	hypothetical protein, partial [Streptococcus agalactiae].	28.82	347	210	11	5	341	3	322	1e-22	110
rs:WP_044775889	DNA topoisomerase I [Streptococcus suis].	24.71	526	310	17	7	504	18	485	1e-22	112
rs:WP_018257964	DNA topoisomerase I [Halomicrobium katesii].	22.84	626	399	22	7	602	4	575	1e-22	113
tr:F0IUZ5_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	629	379	21	7	607	19	573	1e-22	112
rs:WP_024385723	DNA topoisomerase I [Streptococcus suis].	24.71	526	310	17	7	504	18	485	1e-22	112
tr:F3SHN7_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	629	379	21	7	607	19	573	1e-22	112
rs:WP_016368965	DNA topoisomerase I, partial [Lactobacillus paracasei].	28.02	439	269	15	93	504	17	435	1e-22	112
rs:WP_032912452	DNA topoisomerase I [Streptococcus sanguinis].	23.69	629	378	21	7	607	16	570	1e-22	112
rs:WP_033704523	DNA topoisomerase, partial [Enterococcus faecium].	30.65	248	155	8	5	245	3	240	1e-22	108
rs:WP_014705479	DNA topoisomerase I [Methylophaga nitratireducenticrescens].	24.77	537	317	18	7	505	6	493	1e-22	113
tr:A0A0B5HG25_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.29	554	364	14	4	543	1	507	1e-22	112
rs:WP_044306347	DNA topoisomerase I [Campylobacter jejuni].	25.11	438	286	13	89	505	60	476	1e-22	112
rs:WP_014767919	DNA topoisomerase I [Desulfurococcus fermentans].	24.09	631	382	22	7	599	16	587	1e-22	112
rs:WP_021172441	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	1e-22	112
rs:WP_006834330	DNA topoisomerase I [Erythrobacter sp. SD-21].	27.82	550	284	27	7	510	4	486	1e-22	113
rs:WP_033768917	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	1e-22	112
rs:WP_029998768	DNA topoisomerase I [Streptococcus suis].	24.71	526	310	17	7	504	18	485	1e-22	112
tr:F9E0C3_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	629	379	21	7	607	19	573	1e-22	112
rs:WP_001953097	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	1e-22	112
rs:WP_014704495	DNA topoisomerase I [Methylophaga frappieri].	24.67	535	320	17	7	505	6	493	1e-22	112
rs:WP_003678435	DNA topoisomerase I [Lactobacillus coryniformis].	25.89	533	313	22	1	504	1	480	1e-22	112
rs:WP_020448704	DNA topoisomerase I [Candidatus Methanomassiliicoccus intestinalis].	24.73	558	347	18	7	542	5	511	1e-22	112
rs:WP_045004125	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	1e-22	112
tr:F0IMD6_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.69	629	378	21	7	607	19	573	1e-22	112
rs:WP_044679670	DNA topoisomerase I [Streptococcus suis].	24.90	526	309	17	7	504	18	485	1e-22	112
rs:WP_032908166	DNA topoisomerase I [Streptococcus sanguinis].	23.53	629	379	21	7	607	16	570	1e-22	112
rs:WP_032906559	DNA topoisomerase I [Streptococcus sanguinis].	24.62	520	317	17	7	504	16	482	1e-22	112
rs:WP_026444414	DNA topoisomerase I [Acinetobacter sp. UNC436CL71CviS28].	25.84	538	313	21	80	581	46	533	1e-22	112
rs:WP_000681499	DNA topoisomerase I [Helicobacter pylori].	27.44	492	280	19	51	505	24	475	1e-22	112
rs:WP_010979235	DNA topoisomerase I [Sulfolobus tokodaii].	24.62	593	377	22	7	579	11	553	1e-22	112
rs:WP_032823308	DNA topoisomerase I [Oenococcus oeni].	25.70	533	298	20	7	504	12	481	1e-22	112
rs:WP_029645004	MULTISPECIES: DNA topoisomerase, partial [Enterococcus].	31.23	253	154	9	5	248	3	244	1e-22	108
rs:WP_032914166	DNA topoisomerase I [Streptococcus sanguinis].	24.62	520	317	17	7	504	16	482	1e-22	112
rs:WP_018372628	DNA topoisomerase I [Streptococcus merionis].	24.95	521	314	18	7	504	19	485	1e-22	112
rs:WP_000210271	MULTISPECIES: DNA topoisomerase I [Gammaproteobacteria].	24.72	530	308	19	5	505	3	470	1e-22	112
rs:WP_021582057	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	1e-22	112
rs:WP_002207369	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	1e-22	112
rs:WP_038837322	DNA topoisomerase I [Campylobacter coli].	25.46	436	287	12	89	505	60	476	1e-22	112
tr:E8KPH4_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.62	520	317	17	7	504	19	485	1e-22	112
rs:WP_024380821	DNA topoisomerase I [Streptococcus suis].	24.71	526	310	17	7	504	18	485	1e-22	112
rs:WP_033754862	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	2e-22	112
rs:WP_001941587	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_000681460	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	17	89	505	59	475	2e-22	112
rs:WP_038839415	DNA topoisomerase I [Campylobacter coli].	25.46	436	287	12	89	505	60	476	2e-22	112
rs:WP_000681521	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
tr:F3USB2_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.62	520	317	17	7	504	19	485	2e-22	112
rs:WP_001950177	DNA topoisomerase I [Helicobacter pylori].	28.29	449	258	17	89	505	59	475	2e-22	112
tr:T1BI43_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD53810.1}; Flags: Fragment;	28.66	335	199	11	24	346	77	383	2e-22	109
rs:WP_028494122	DNA topoisomerase I [Thermus antranikianii].	25.45	554	305	22	7	505	1	501	2e-22	112
rs:WP_001974755	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
tr:F8XV09_9GAMM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGQ63552.1}; Flags: Fragment;	29.52	271	166	7	8	269	5	259	2e-22	108
rs:WP_002860825	DNA topoisomerase I [Campylobacter jejuni].	24.89	438	287	13	89	505	60	476	2e-22	112
rs:WP_000681402	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
tr:J6HK20_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJY30873.1}; Flags: Fragment;	31.60	250	154	8	5	247	3	242	2e-22	108
tr:L2J129_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELA74246.1};	29.88	251	160	7	5	248	3	244	2e-22	108
rs:WP_043959647	DNA topoisomerase I [Lysobacter sp. A03].	24.35	538	322	17	7	505	6	497	2e-22	112
rs:WP_033620616	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	2e-22	112
tr:F7QV08_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.65	434	272	15	93	504	36	449	2e-22	112
rs:WP_001970510	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_005689318	DNA topoisomerase I [Lactobacillus rhamnosus].	26.18	531	316	20	1	504	1	482	2e-22	112
rs:WP_000681512	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_044672450	DNA topoisomerase I [Streptococcus suis].	24.71	526	310	17	7	504	18	485	2e-22	112
rs:WP_027837687	DNA topoisomerase I [Mastigocoleus testarum].	26.84	544	317	22	4	510	2	501	2e-22	112
rs:WP_000681524	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_002798917	DNA topoisomerase I [Campylobacter coli].	24.89	438	287	13	89	505	60	476	2e-22	112
rs:WP_000681436	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_042700233	DNA topoisomerase I [Methanocorpusculum bavaricum].	24.12	539	349	18	7	532	4	495	2e-22	112
rs:WP_001944744	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_000681429	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_042762851	DNA topoisomerase I [Streptococcus sanguinis].	23.53	629	379	21	7	607	16	570	2e-22	112
rs:WP_032911974	DNA topoisomerase I [Streptococcus sanguinis].	23.53	629	379	21	7	607	16	570	2e-22	112
rs:WP_021186885	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	2e-22	112
rs:WP_009660457	DNA topoisomerase I [Streptococcus sp. AS14].	23.69	629	378	21	7	607	16	570	2e-22	112
rs:WP_000681421	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_008471813	DNA topoisomerase I [Lactobacillus hominis].	26.10	525	308	20	7	505	11	481	2e-22	112
rs:WP_026943886	DNA topoisomerase I [Helicobacter rodentium].	25.39	579	362	17	47	599	20	554	2e-22	112
tr:M5YMY3_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_000681440	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_000681511	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_032911148	DNA topoisomerase I [Streptococcus sanguinis].	24.62	520	317	17	7	504	16	482	2e-22	112
rs:WP_002812072	DNA topoisomerase I [Nitrosococcus oceani].	24.24	557	313	16	3	505	2	503	2e-22	112
rs:WP_033592450	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_001940876	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_029655964	DNA topoisomerase, partial [Enterococcus faecalis].	26.05	403	280	9	151	544	1	394	2e-22	111
rs:WP_002812170	DNA topoisomerase I [Campylobacter coli].	25.28	439	284	13	89	505	60	476	2e-22	112
rs:WP_003524694	hypothetical protein, partial [[Clostridium] clostridioforme].	27.15	291	185	7	276	549	1	281	2e-22	110
rs:WP_028388168	DNA topoisomerase I [Legionella fairfieldensis].	26.31	536	311	18	7	505	6	494	2e-22	112
rs:WP_033613056	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_021954365	DNA topoisomerase [Clostridium sp. CAG:921].	27.19	526	290	22	7	504	6	466	2e-22	112
rs:WP_000681505	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_002822893	DNA topoisomerase I [Campylobacter coli].	25.28	439	284	13	89	505	60	476	2e-22	112
rs:WP_038685971	DNA topoisomerase I [Stenotrophomonas rhizophila].	25.04	591	344	19	7	563	6	531	2e-22	112
rs:WP_004513038	DNA topoisomerase I [Geobacter metallireducens].	26.03	534	312	18	7	505	6	491	2e-22	112
rs:WP_033758945	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_000681488	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	16	89	505	59	475	2e-22	112
rs:WP_000681430	DNA topoisomerase I [Helicobacter pylori].	28.29	449	258	17	89	505	59	475	2e-22	112
rs:WP_000681444	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
tr:F0I7E3_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	629	379	21	7	607	19	573	2e-22	112
rs:WP_042744536	DNA topoisomerase I, partial [Oenococcus oeni].	25.52	533	299	20	7	504	12	481	2e-22	112
rs:WP_032907384	DNA topoisomerase I [Streptococcus sanguinis].	23.21	629	381	21	7	607	16	570	2e-22	112
rs:WP_008766575	DNA topoisomerase I [Bacteroides sp. 1_1_6].	25.11	458	310	12	97	544	39	473	2e-22	112
rs:WP_015644696	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	17	89	505	59	475	2e-22	112
rs:WP_013969129	DNA topoisomerase I [Treponema caldaria].	24.38	640	364	27	5	606	14	571	2e-22	112
rs:WP_002869288	DNA topoisomerase I [Campylobacter jejuni].	24.89	438	287	13	89	505	60	476	2e-22	112
rs:WP_032915919	DNA topoisomerase I [Streptococcus sanguinis].	23.53	629	379	21	7	607	16	570	2e-22	112
rs:WP_035582537	DNA topoisomerase I [Hyphomonas jannaschiana].	26.70	528	309	22	7	505	4	482	2e-22	112
rs:WP_016309110	DNA topoisomerase I [Enterorhabdus caecimuris].	23.63	567	368	19	65	607	107	632	2e-22	112
rs:WP_032212518	DNA topoisomerase III, partial [Escherichia coli].	28.25	354	235	11	7	354	4	344	2e-22	108
rs:WP_024376241	DNA topoisomerase I [Streptococcus suis].	24.71	526	310	17	7	504	18	485	2e-22	112
rs:WP_002780003	DNA topoisomerase I [Campylobacter coli].	25.34	438	283	13	89	504	60	475	2e-22	112
rs:WP_032909719	DNA topoisomerase I [Streptococcus sanguinis].	25.00	520	315	18	7	504	16	482	2e-22	112
rs:WP_042631886	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	2e-22	112
rs:WP_044598192	DNA topoisomerase I [Campylobacter peloridis].	25.31	482	309	15	47	504	21	475	3e-22	112
rs:WP_040422144	DNA topoisomerase I [Corynebacterium lipophiloflavum].	24.58	541	327	19	5	505	11	510	3e-22	112
tr:C0XU91_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.58	541	327	19	5	505	20	519	3e-22	112
tr:F3UAY0_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	629	379	21	7	607	19	573	3e-22	112
tr:F2BS11_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	629	379	21	7	607	19	573	3e-22	112
rs:WP_013034676	DNA topoisomerase I [Nitrosococcus halophilus].	25.00	548	313	18	7	505	6	504	3e-22	112
rs:WP_033748728	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	3e-22	112
rs:WP_001934270	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	3e-22	112
rs:WP_001947707	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	17	89	505	59	475	3e-22	112
rs:WP_022157133	DNA topoisomerase [Firmicutes bacterium CAG:145].	28.25	577	304	26	5	553	19	513	3e-22	111
rs:WP_002206977	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	3e-22	112
rs:WP_038813768	DNA topoisomerase I [Campylobacter jejuni].	23.85	520	326	17	7	505	6	476	3e-22	111
rs:WP_000681423	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	3e-22	112
rs:WP_017842229	DNA topoisomerase I [Methylomicrobium buryatense].	26.11	540	308	20	7	505	6	495	3e-22	112
rs:WP_032806012	DNA topoisomerase I [Oenococcus oeni].	25.52	533	299	20	7	504	12	481	3e-22	111
rs:WP_000681432	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	3e-22	111
rs:WP_015052783	DNA topoisomerase I [Methanolobus psychrophilus].	23.76	543	355	16	7	539	10	503	3e-22	111
rs:WP_044773639	DNA topoisomerase I [Streptococcus suis].	24.71	526	310	17	7	504	18	485	3e-22	111
rs:WP_031942101	DNA topoisomerase III, partial [Staphylococcus aureus].	31.15	244	153	6	306	544	9	242	3e-22	108
rs:WP_013562560	DNA topoisomerase I [Desulfurococcus mucosus].	25.04	615	384	25	7	594	24	588	3e-22	111
rs:WP_033482235	DNA topoisomerase III, partial [Xanthomonas axonopodis].	27.53	316	213	8	8	322	5	305	3e-22	107
rs:WP_032822705	DNA topoisomerase I [Oenococcus oeni].	25.47	534	298	20	7	504	12	481	3e-22	111
rs:WP_033599198	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	3e-22	111
rs:WP_000681439	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	3e-22	111
rs:WP_040421020	DNA topoisomerase I [Corynebacterium timonense].	24.82	564	343	22	2	522	8	533	3e-22	112
rs:WP_039088321	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	3e-22	111
rs:WP_040155991	DNA topoisomerase I [Helicobacter pylori].	28.06	449	259	16	89	505	59	475	3e-22	111
rs:WP_032820195	DNA topoisomerase I, partial [Oenococcus oeni].	25.52	533	299	20	7	504	15	484	3e-22	111
rs:WP_002779424	DNA topoisomerase I [Campylobacter coli].	24.89	438	287	13	89	505	60	476	3e-22	111
tr:F0FTK4_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	629	379	21	7	607	19	573	3e-22	111
tr:F2CD39_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	629	379	21	7	607	19	573	3e-22	111
rs:WP_038831465	DNA topoisomerase I [Campylobacter coli].	25.51	439	283	13	89	505	60	476	3e-22	111
rs:WP_039082230	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	17	89	505	59	475	3e-22	111
rs:WP_000681403	DNA topoisomerase I [Helicobacter pylori].	28.29	449	258	16	89	505	59	475	3e-22	111
rs:WP_018865472	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	26.07	537	311	22	7	505	6	494	3e-22	112
tr:F3UXP6_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.21	629	381	21	7	607	19	573	3e-22	111
rs:WP_015086777	DNA topoisomerase I [Helicobacter pylori].	28.44	450	256	16	89	505	59	475	3e-22	111
rs:WP_022969384	DNA topoisomerase I [Arenimonas oryziterrae].	24.11	593	356	19	7	568	6	535	3e-22	111
rs:WP_000681501	DNA topoisomerase I [Helicobacter pylori].	27.88	452	256	16	89	505	59	475	3e-22	111
rs:WP_001926900	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	3e-22	111
rs:WP_015449009	MULTISPECIES: DNA topoisomerase I [Rhodanobacter].	26.34	543	308	21	7	505	6	500	3e-22	111
rs:WP_011108421	DNA topoisomerase I [Bacteroides thetaiotaomicron].	23.15	553	353	18	4	531	1	506	3e-22	111
rs:WP_038833965	DNA topoisomerase I [Campylobacter coli].	25.51	439	283	13	89	505	60	476	3e-22	111
rs:WP_001963288	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	3e-22	111
rs:WP_002791644	DNA topoisomerase I [Campylobacter coli].	24.89	438	287	13	89	505	60	476	3e-22	111
rs:WP_007513531	DNA topoisomerase I [Rhodanobacter denitrificans].	26.34	543	308	21	7	505	6	500	3e-22	111
rs:WP_006302460	DNA topoisomerase [Atopobium vaginae].	24.81	524	320	19	65	563	109	583	3e-22	111
tr:F2C637_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	520	315	18	7	504	19	485	3e-22	111
rs:WP_037332935	DNA topoisomerase I [Salinisphaera hydrothermalis].	25.50	553	318	20	7	512	6	511	4e-22	111
rs:WP_040179383	DNA topoisomerase I [Helicobacter pylori].	28.06	449	259	16	89	505	59	475	4e-22	111
tr:M5AIA3_LACBR	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:BAN08120.1};	28.24	301	186	8	5	292	3	286	4e-22	107
rs:WP_043104337	DNA topoisomerase I [Xanthomonadaceae bacterium 3.5X].	27.07	543	297	22	7	505	6	493	4e-22	111
rs:WP_000681434	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	4e-22	111
rs:WP_032909544	DNA topoisomerase I [Streptococcus sanguinis].	23.53	629	379	21	7	607	16	570	4e-22	111
rs:WP_032908811	DNA topoisomerase I [Streptococcus sanguinis].	23.53	629	379	21	7	607	16	570	4e-22	111
rs:WP_000681490	DNA topoisomerase I [Helicobacter pylori].	28.38	451	255	17	89	505	59	475	4e-22	111
rs:WP_015058240	DNA topoisomerase III [Escherichia coli].	30.49	246	150	5	318	543	1	245	4e-22	109
rs:WP_002815000	DNA topoisomerase I [Campylobacter coli].	25.34	438	283	13	89	504	60	475	4e-22	111
rs:WP_024532816	DNA topoisomerase I [Streptococcus suis].	24.57	521	317	17	7	504	18	485	4e-22	111
rs:WP_042880445	hypothetical protein [Bacillus anthracis].	31.84	245	142	9	5	238	3	233	4e-22	106
tr:D4ELA0_ENTFL	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EFE19574.1};	32.46	228	138	8	5	225	3	221	4e-22	106
tr:K2CUE4_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	25.82	519	308	13	7	494	6	478	4e-22	109
rs:WP_000681425	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	4e-22	111
rs:WP_034371259	DNA topoisomerase I, partial [Helicobacter sp. MIT 05-5293].	25.85	441	289	11	85	504	55	478	4e-22	110
rs:WP_045475869	DNA topoisomerase I [Thioploca ingrica].	25.78	543	305	20	7	505	6	494	4e-22	111
rs:WP_042866267	DNA topoisomerase III, partial [Bacillus cereus].	32.05	234	141	6	116	347	4	221	4e-22	106
rs:WP_026475992	DNA topoisomerase I [Alkaliphilus transvaalensis].	26.07	610	340	24	7	583	6	537	4e-22	111
rs:WP_013159046	DNA topoisomerase I [Meiothermus silvanus].	24.91	534	317	22	5	505	6	488	4e-22	111
rs:WP_002818660	DNA topoisomerase I [Campylobacter coli].	25.34	438	283	13	89	504	60	475	4e-22	111
rs:WP_033916179	DNA topoisomerase I [Campylobacter sputorum].	26.24	442	276	15	89	505	59	475	4e-22	111
rs:WP_037614931	DNA topoisomerase I [Streptococcus sinensis].	23.37	629	380	21	7	607	16	570	4e-22	111
rs:WP_031923562	DNA topoisomerase III, partial [Staphylococcus aureus].	31.15	244	153	6	306	544	5	238	4e-22	108
rs:WP_033763286	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	17	89	505	59	475	4e-22	111
rs:WP_013129043	DNA topoisomerase I [Thermosphaera aggregans].	25.22	563	349	21	7	548	26	537	4e-22	111
rs:WP_031834942	MULTISPECIES: DNA topoisomerase, partial [Bacilli].	32.46	228	138	8	5	225	3	221	4e-22	105
rs:WP_045778769	DNA topoisomerase I [Methylococcaceae bacterium Sn10-6].	25.69	541	309	18	7	505	6	495	4e-22	111
tr:D2EGP7_PARA4	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.75	501	330	12	48	540	72	523	4e-22	111
rs:WP_001954546	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	4e-22	111
rs:WP_001956918	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	4e-22	111
rs:WP_005729974	hypothetical protein [Lactobacillus crispatus].	25.62	601	347	22	5	526	3	582	4e-22	111
rs:WP_006111841	DNA topoisomerase I [Halorubrum coriense].	22.59	540	347	15	7	498	8	524	4e-22	111
rs:WP_001950705	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	4e-22	111
rs:WP_016477303	DNA topoisomerase I [Atopobium sp. oral taxon 199].	24.66	515	331	17	65	563	109	582	4e-22	111
rs:WP_044134826	DNA topoisomerase I, partial [Bacteroides fragilis].	23.15	553	353	18	4	531	1	506	4e-22	110
rs:WP_001946536	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	4e-22	111
rs:WP_039095210	DNA topoisomerase I [Kirrobacter mercurialis].	27.14	549	291	27	7	510	4	488	4e-22	111
tr:N1ZFX7_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.12	320	196	10	7	322	4	293	4e-22	107
rs:WP_039091272	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	17	89	505	59	475	5e-22	111
rs:WP_045614986	DNA topoisomerase I [Streptococcus mitis].	25.00	520	315	18	7	504	17	483	5e-22	110
rs:WP_002817146	DNA topoisomerase I [Oenococcus oeni].	27.07	447	257	16	93	504	69	481	5e-22	110
rs:WP_038848444	DNA topoisomerase I [Campylobacter coli].	25.46	436	287	12	89	505	60	476	5e-22	110
rs:WP_033869926	DNA topoisomerase III, partial [Staphylococcus aureus].	30.94	320	203	10	5	317	3	311	5e-22	107
rs:WP_046655876	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	5e-22	111
rs:WP_042080261	DNA topoisomerase III, partial [Escherichia coli].	27.04	318	213	9	8	315	5	313	5e-22	107
rs:WP_001935335	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	5e-22	111
rs:WP_000681509	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	5e-22	110
rs:WP_038417165	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	5e-22	110
rs:WP_000681437	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	5e-22	110
rs:WP_029808434	DNA topoisomerase I [Vibrio parahaemolyticus].	26.76	482	291	17	91	553	58	496	5e-22	110
rs:WP_006626394	DNA topoisomerase I [Bulleidia extructa].	24.39	615	368	23	7	593	5	550	5e-22	110
rs:WP_040235479	DNA topoisomerase III, partial [Klebsiella pneumoniae].	27.89	337	218	10	7	333	4	325	5e-22	107
rs:WP_033786383	DNA topoisomerase I [Helicobacter pylori].	28.06	449	259	16	89	505	59	475	5e-22	110
rs:WP_013778279	DNA topoisomerase I [Tepidanaerobacter acetatoxydans].	27.12	531	301	20	7	505	6	482	5e-22	110
rs:WP_036869100	DNA topoisomerase I, partial [Prevotella bivia].	29.82	285	172	9	262	531	48	319	5e-22	109
rs:WP_015427359	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	17	89	505	59	475	5e-22	110
rs:WP_034129460	DNA topoisomerase I [Acinetobacter baumannii].	25.65	538	314	21	80	581	46	533	5e-22	110
rs:WP_023846762	DNA topoisomerase I, partial [Porphyromonas gingivalis].	27.30	348	216	11	77	417	18	335	5e-22	107
rs:WP_000681513	DNA topoisomerase I [Helicobacter pylori].	28.06	449	259	17	89	505	59	475	5e-22	110
rs:WP_032811318	DNA topoisomerase I, partial [Oenococcus oeni].	25.52	533	299	20	7	504	12	481	5e-22	110
rs:WP_001916775	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	17	89	505	59	475	5e-22	110
rs:WP_020974013	DNA topoisomerase I [Campylobacter coli].	25.51	439	283	13	89	505	60	476	5e-22	110
rs:WP_001922728	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	5e-22	110
rs:WP_015060283	DNA topoisomerase I [uncultured bacterium HHV35].	25.65	538	314	21	80	581	46	533	5e-22	110
rs:WP_019624066	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	26.25	541	305	22	7	505	6	494	5e-22	111
rs:WP_039090455	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	5e-22	110
rs:WP_033616372	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	5e-22	110
rs:WP_002932097	DNA topoisomerase I [Campylobacter jejuni].	25.11	438	286	13	89	505	60	476	5e-22	110
rs:WP_002922085	DNA topoisomerase I [Campylobacter jejuni].	25.23	440	283	14	89	505	60	476	5e-22	110
tr:E1L2T0_9ACTN	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	24.75	501	299	15	65	532	109	564	5e-22	111
rs:WP_001938164	DNA topoisomerase I [Helicobacter pylori].	28.06	449	259	17	89	505	59	475	5e-22	110
rs:WP_032823878	DNA topoisomerase I [Oenococcus oeni].	25.52	533	299	20	7	504	12	481	5e-22	110
rs:WP_000681398	DNA topoisomerase I [Helicobacter pylori].	28.06	449	259	17	89	505	59	475	5e-22	110
rs:WP_040327148	DNA topoisomerase, partial [Atopobium vaginae].	24.75	501	299	15	65	532	109	564	5e-22	111
rs:WP_029175455	DNA topoisomerase I [Streptococcus suis].	24.71	526	310	17	7	504	18	485	6e-22	110
rs:WP_044653275	DNA topoisomerase I [Bacteroides acidifaciens].	23.05	551	356	17	4	531	1	506	6e-22	110
rs:WP_018864622	DNA topoisomerase I [Thioalkalivibrio sp. ARh3].	26.25	541	305	22	7	505	6	494	6e-22	110
tr:F0I228_STRSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.85	629	377	22	7	607	19	573	6e-22	110
rs:WP_001939020	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	6e-22	110
rs:WP_033609574	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	17	89	505	59	475	6e-22	110
rs:WP_002691935	DNA topoisomerase I [Beggiatoa alba].	25.00	536	318	17	7	505	6	494	6e-22	110
rs:WP_000209234	DNA topoisomerase III, partial [Bacillus anthracis].	31.84	245	142	9	5	238	3	233	6e-22	106
rs:WP_036610755	DNA topoisomerase I [Oribacterium sp. P6A1].	24.09	606	360	22	7	586	6	537	6e-22	110
tr:A0A060HRZ8_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.31	574	351	21	5	553	3	529	6e-22	110
tr:W1FZU6_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	27.22	316	211	9	8	313	5	311	6e-22	107
rs:WP_000681503	DNA topoisomerase I [Helicobacter pylori].	27.88	452	256	16	89	505	59	475	6e-22	110
rs:WP_000681502	DNA topoisomerase I [Helicobacter pylori].	27.88	452	256	16	89	505	59	475	6e-22	110
rs:WP_001928282	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	6e-22	110
rs:WP_012106401	DNA topoisomerase I [Methanoregula boonei].	23.12	558	362	21	7	550	4	508	6e-22	111
rs:WP_033596589	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	6e-22	110
rs:WP_000681491	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	17	89	505	59	475	6e-22	110
rs:WP_006654231	DNA topoisomerase I [Natrialba hulunbeirensis].	22.75	567	365	20	7	541	4	529	6e-22	110
rs:WP_000681407	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	6e-22	110
rs:WP_000681406	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	6e-22	110
rs:WP_002822536	DNA topoisomerase I [Oenococcus oeni].	25.52	533	299	20	7	504	12	481	6e-22	110
rs:WP_001981450	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	6e-22	110
rs:WP_001918750	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	6e-22	110
rs:WP_002349115	toprim domain protein, partial [Enterococcus faecium].	32.07	237	144	8	5	234	3	229	6e-22	105
rs:WP_000681422	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	6e-22	110
rs:WP_021678245	DNA topoisomerase, partial [Porphyromonas gingivalis].	25.66	378	233	13	178	531	1	354	6e-22	107
rs:WP_041631689	DNA topoisomerase I [Corynebacterium maris].	25.92	463	283	16	86	505	77	522	7e-22	110
rs:WP_032913578	DNA topoisomerase I [Streptococcus sanguinis].	23.85	629	377	22	7	607	16	570	7e-22	110
rs:WP_034686384	DNA topoisomerase I [Acinetobacter baumannii].	25.65	538	314	21	80	581	46	533	7e-22	110
rs:WP_012809178	DNA topoisomerase [Atopobium parvulum].	22.50	511	346	15	65	563	109	581	7e-22	110
rs:WP_039583461	DNA topoisomerase III, partial [Xanthomonas axonopodis].	27.85	316	212	8	8	322	5	305	7e-22	107
rs:WP_040759096	DNA topoisomerase III, partial [Sporosarcina newyorkensis].	28.44	334	214	13	7	332	6	322	7e-22	107
rs:WP_033770665	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	7e-22	110
rs:WP_001948369	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	7e-22	110
rs:WP_000681420	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	7e-22	110
tr:F9DSK4_9BACL	SubName: Full=DNA topoisomerase TopB {ECO:0000313|EMBL:EGQ26216.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EGQ26216.1};	28.44	334	214	13	7	332	6	322	7e-22	107
rs:WP_033478926	DNA topoisomerase III, partial [Xanthomonas perforans].	27.53	316	213	8	8	322	5	305	7e-22	107
rs:WP_002863984	DNA topoisomerase I [Campylobacter jejuni].	24.89	438	287	13	89	505	60	476	7e-22	110
rs:WP_000681413	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	7e-22	110
rs:WP_035572607	DNA topoisomerase I [Hyphomonas adhaerens].	26.14	528	312	20	7	505	4	482	7e-22	110
rs:WP_000681515	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	7e-22	110
rs:WP_037372277	DNA topoisomerase I [Selenomonas noxia].	24.57	635	362	27	7	602	34	590	7e-22	110
rs:WP_000681504	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	7e-22	110
rs:WP_013143479	DNA topoisomerase I [Staphylothermus hellenicus].	23.68	587	372	23	6	566	56	592	7e-22	110
rs:WP_021177330	DNA topoisomerase I [Helicobacter pylori].	28.34	441	253	15	89	500	59	465	7e-22	110
rs:WP_008026503	DNA topoisomerase III [Bacteroides xylanisolvens].	22.97	553	354	18	4	531	1	506	7e-22	110
rs:WP_014343005	DNA topoisomerase III [Klebsiella pneumoniae].	27.27	330	213	9	7	322	4	320	7e-22	107
rs:WP_034996971	DNA topoisomerase I [Corynebacterium sp. GD7].	25.46	542	326	20	5	505	7	511	7e-22	110
rs:WP_023524932	DNA topoisomerase I [Leptospirillum sp. Group II 'C75'].	24.90	526	303	19	7	505	4	464	7e-22	110
rs:WP_045503129	DNA topoisomerase I [Streptococcus gordonii].	23.78	635	370	23	7	607	16	570	7e-22	110
tr:S5SRZ9_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.92	463	283	16	86	505	65	510	7e-22	110
rs:WP_032807188	DNA topoisomerase I [Oenococcus oeni].	25.52	533	299	20	7	504	12	481	8e-22	110
rs:WP_001972760	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	8e-22	110
rs:WP_008628880	DNA topoisomerase, partial [Paraprevotella xylaniphila].	28.00	275	189	6	278	550	51	318	8e-22	107
rs:WP_005253290	DNA topoisomerase I [Acinetobacter sp. CIP 102136].	26.18	531	320	20	80	581	46	533	8e-22	110
rs:WP_036105783	DNA topoisomerase I [Lysobacter capsici].	23.69	591	351	20	7	563	6	530	8e-22	110
rs:WP_046658174	DNA topoisomerase I [Lysobacter capsici].	23.69	591	351	20	7	563	6	530	8e-22	110
rs:WP_001937468	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	8e-22	110
rs:WP_000681497	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	8e-22	110
rs:WP_017913294	DNA topoisomerase I [Xanthomonas sp. SHU166].	25.68	588	343	20	7	563	6	530	8e-22	110
rs:WP_011836973	DNA topoisomerase I [Streptococcus sanguinis].	23.85	629	377	22	7	607	19	573	8e-22	110
rs:WP_034220760	DNA topoisomerase I [Arenimonas donghaensis].	25.00	588	347	21	7	563	6	530	8e-22	110
rs:WP_034789719	DNA topoisomerase I [Hyphomonas beringensis].	26.33	528	311	20	7	505	4	482	8e-22	110
rs:WP_013495388	DNA topoisomerase I [Thermaerobacter marianensis].	25.43	578	332	22	5	553	4	511	8e-22	110
rs:WP_017914936	DNA topoisomerase I [Xanthomonas sp. SHU308].	25.68	588	343	20	7	563	6	530	8e-22	110
tr:Q702B0_9CREN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.96	561	355	18	7	545	15	531	8e-22	110
rs:WP_005368869	MULTISPECIES: DNA topoisomerase I [Methylomicrobium].	25.84	596	330	23	7	562	6	529	8e-22	110
rs:WP_046165540	DNA topoisomerase I [Streptococcus gordonii].	23.89	632	373	23	7	607	16	570	8e-22	110
tr:T3QPZ8_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.50	254	129	7	307	544	2	226	8e-22	107
rs:WP_028027328	DNA topoisomerase [Enterorhabdus mucosicola].	23.63	567	368	19	65	607	107	632	8e-22	110
rs:WP_002839175	DNA topoisomerase I [Campylobacter coli].	25.06	439	285	13	89	505	60	476	8e-22	110
rs:WP_000681465	DNA topoisomerase I [Helicobacter pylori].	28.06	449	259	16	89	505	59	475	8e-22	110
rs:WP_042037109	DNA topoisomerase III, partial [Escherichia coli].	30.29	340	195	11	232	546	9	331	8e-22	108
tr:T0YZJ2_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD37372.1}; Flags: Fragment;	31.36	236	150	6	1	235	131	355	8e-22	107
rs:WP_004321457	DNA topoisomerase I [Campylobacter showae].	27.00	437	279	13	89	505	59	475	8e-22	110
rs:WP_029187270	DNA topoisomerase I [Streptococcus suis].	24.52	526	311	17	7	504	18	485	8e-22	110
rs:WP_020564824	DNA topoisomerase I [Methylosarcina fibrata].	25.76	594	333	21	7	562	6	529	9e-22	110
rs:WP_041789689	DNA topoisomerase I [Streptococcus gordonii].	23.46	635	372	22	7	607	16	570	9e-22	110
rs:WP_002821098	DNA topoisomerase I [Oenococcus oeni].	25.52	533	299	20	7	504	12	481	9e-22	110
tr:A8AXH4_STRGC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.46	635	372	22	7	607	19	573	9e-22	110
rs:WP_035308717	DNA topoisomerase, partial [Clostridium sp. HMP27].	26.58	301	194	8	7	295	5	290	9e-22	106
rs:WP_032808585	DNA topoisomerase I [Oenococcus oeni].	25.52	533	299	20	7	504	12	481	9e-22	110
rs:WP_043094550	DNA topoisomerase I [Xanthomonas sacchari].	25.68	588	343	20	7	563	6	530	9e-22	110
tr:F5RLS8_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.20	635	364	31	7	607	20	577	9e-22	110
rs:WP_001920473	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	9e-22	110
rs:WP_038031619	DNA topoisomerase I [Thermus sp. NMX2.A1].	25.27	554	306	22	7	505	1	501	9e-22	110
tr:M3QQR9_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.94	451	257	16	89	505	59	475	9e-22	110
rs:WP_039675625	DNA topoisomerase I [Sulfurospirillum sp. MES].	25.19	520	319	18	7	505	9	479	9e-22	110
rs:WP_020992625	DNA topoisomerase 1 [Streptococcus sp. 2_1_36FAA].	23.46	635	372	22	7	607	16	570	9e-22	110
rs:WP_014586061	DNA topoisomerase I [Methanosaeta harundinacea].	22.36	492	322	11	75	550	54	501	9e-22	110
rs:WP_024377726	DNA topoisomerase I [Streptococcus suis].	24.44	532	304	18	7	504	18	485	9e-22	110
rs:WP_000681517	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	16	89	505	59	475	9e-22	110
rs:WP_000681426	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	9e-22	110
gp:CP000408_998	DNA topoisomerase I [Streptococcus suis 98HAH33]	25.44	452	286	13	81	504	9	437	9e-22	110
rs:WP_032190916	DNA topoisomerase III, partial [Escherichia coli].	27.16	313	209	9	8	310	5	308	9e-22	106
tr:K2B533_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.57	542	304	21	7	505	6	496	9e-22	110
rs:WP_018578499	DNA topoisomerase I [Legionella shakespearei].	27.34	534	307	17	7	505	6	493	9e-22	110
rs:WP_013413259	DNA topoisomerase I [Methanothermus fervidus].	28.15	547	312	26	6	530	7	494	9e-22	110
rs:WP_002823480	DNA topoisomerase I [Campylobacter coli].	25.06	439	285	13	89	505	60	476	9e-22	110
rs:WP_032177407	DNA topoisomerase III, partial [Escherichia coli].	31.56	282	166	8	287	546	25	301	9e-22	107
rs:WP_002820441	DNA topoisomerase I [Oenococcus oeni].	25.52	533	299	20	7	504	12	481	9e-22	110
rs:WP_000681441	DNA topoisomerase I [Helicobacter pylori].	28.06	449	259	17	89	505	59	475	9e-22	110
rs:WP_032820757	DNA topoisomerase I [Oenococcus oeni].	25.52	533	299	20	7	504	12	481	1e-21	110
rs:WP_000681445	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	1e-21	110
rs:WP_005874995	hypothetical protein, partial [Enterococcus faecium].	27.73	321	197	13	253	563	26	321	1e-21	108
rs:WP_000681424	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	1e-21	110
rs:WP_000681419	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	1e-21	110
rs:WP_002800263	DNA topoisomerase I [Campylobacter coli].	25.06	439	285	13	89	505	60	476	1e-21	110
rs:WP_020396072	hypothetical protein [Thiothrix disciformis].	26.92	535	307	20	7	505	6	492	1e-21	110
tr:T0ZCB8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD42728.1};	25.58	563	333	22	7	540	5	510	1e-21	110
rs:WP_032816112	DNA topoisomerase I [Oenococcus oeni].	25.52	533	299	20	7	504	12	481	1e-21	110
rs:WP_002785538	DNA topoisomerase I [Campylobacter coli].	25.06	439	285	13	89	505	60	476	1e-21	110
rs:WP_042614482	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.38	591	341	22	7	563	6	530	1e-21	110
rs:WP_018879677	DNA topoisomerase I [Thioalkalivibrio sp. ALE9].	26.07	537	311	22	7	505	6	494	1e-21	110
rs:WP_045635329	DNA topoisomerase I [Streptococcus mitis].	23.62	635	371	22	7	607	16	570	1e-21	110
rs:WP_000681427	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	1e-21	110
rs:WP_009754430	DNA topoisomerase I [Streptococcus sp. oral taxon 056].	24.01	629	376	22	7	607	16	570	1e-21	110
tr:K1T893_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC69387.1}; Flags: Fragment;	25.76	295	209	6	300	591	2	289	1e-21	106
rs:WP_013537158	DNA topoisomerase I [Thermovibrio ammonificans].	23.39	620	376	21	7	607	6	545	1e-21	110
rs:WP_027883605	DNA topoisomerase I [Meiothermus rufus].	22.90	607	374	22	1	579	1	541	1e-21	110
rs:WP_004323216	DNA topoisomerase III [Bacteroides ovatus].	23.15	553	353	18	4	531	1	506	1e-21	109
rs:WP_015085368	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	17	89	505	59	475	1e-21	110
rs:WP_000681525	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	17	89	505	59	475	1e-21	110
rs:WP_012803306	DNA topoisomerase [Cryptobacterium curtum].	23.01	552	368	17	65	603	107	614	1e-21	110
rs:WP_040394655	DNA topoisomerase I [Centipeda periodontii].	25.20	635	364	31	7	607	33	590	1e-21	110
rs:WP_041140988	DNA topoisomerase I [Sulfurovum sp. PC08-66].	25.12	430	280	13	97	505	69	477	1e-21	109
rs:WP_000681529	DNA topoisomerase I [Helicobacter pylori].	26.45	533	296	20	7	505	5	475	1e-21	109
rs:WP_015604970	DNA topoisomerase I [Streptococcus oligofermentans].	24.23	520	319	17	7	504	16	482	1e-21	109
rs:WP_000681404	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	16	89	505	59	475	1e-21	109
rs:WP_037958625	DNA topoisomerase I [Sulfurospirillum sp. SCADC].	26.48	438	280	13	89	505	68	484	1e-21	109
rs:WP_001952760	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	17	89	505	59	475	1e-21	109
rs:WP_015718165	DNA topoisomerase I [Thermus scotoductus].	25.58	559	298	23	7	505	1	501	1e-21	110
rs:WP_036176735	hypothetical protein, partial [Lysinibacillus massiliensis].	30.03	293	179	10	47	334	36	307	1e-21	106
rs:WP_041285285	DNA topoisomerase III, partial [Desulfotomaculum gibsoniae].	29.62	287	174	10	292	559	11	288	1e-21	108
rs:WP_022146067	DNA topoisomerase [Firmicutes bacterium CAG:238].	25.90	525	313	19	5	505	20	492	1e-21	109
rs:WP_000681468	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	1e-21	109
tr:R2PZL1_9ENTE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOH89812.1};	30.36	247	154	6	5	243	3	239	1e-21	105
rs:WP_042636706	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	1e-21	109
rs:WP_000681431	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	1e-21	109
rs:WP_016220726	DNA topoisomerase III, partial [Dorea sp. 5-2].	29.28	321	191	10	7	322	4	293	1e-21	105
rs:WP_020851581	DNA topoisomerase I [Xylella fastidiosa].	25.75	598	340	22	7	568	6	535	1e-21	109
rs:WP_033589834	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	1e-21	109
rs:WP_003150200	DNA topoisomerase [Atopobium rimae].	25.24	531	308	21	65	563	109	582	1e-21	110
rs:WP_000681428	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	1e-21	109
rs:WP_039022797	DNA topoisomerase III, partial [Escherichia coli].	31.31	297	177	8	258	531	2	294	1e-21	108
rs:WP_044345975	DNA topoisomerase III, partial [Pseudomonas meliae].	30.31	254	172	5	200	450	67	318	1e-21	106
tr:Q9HS90_HALSA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.65	347	232	8	198	539	19	344	1e-21	109
rs:WP_040423432	DNA topoisomerase I [Corynebacterium genitalium].	24.87	579	342	21	5	544	7	531	1e-21	110
rs:WP_034767886	DNA topoisomerase I [Hyphomonas sp. CY54-11-8].	26.14	528	312	21	7	505	4	482	1e-21	109
rs:WP_033765728	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	17	89	505	59	475	1e-21	109
rs:WP_025309579	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	17	89	505	59	475	1e-21	109
tr:I2X3M9_ECOLX	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EII43599.1};	30.12	332	195	10	242	544	2	325	1e-21	108
rs:WP_015359063	DNA topoisomerase 1 [[Clostridium] stercorarium].	25.57	575	330	24	7	553	6	510	1e-21	109
rs:WP_032340913	DNA topoisomerase III, partial [Escherichia coli].	31.84	267	156	7	287	531	29	291	1e-21	108
tr:R4KED7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.62	287	174	10	292	559	23	300	1e-21	108
rs:WP_027484108	DNA topoisomerase I [Rhodanobacter sp. OR87].	26.15	543	309	21	7	505	6	500	1e-21	109
rs:WP_021174553	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	1e-21	109
rs:WP_037348525	DNA topoisomerase I [Selenomonas sp. F0473].	26.32	532	302	24	7	505	34	508	1e-21	109
tr:T1DDP8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD79519.1}; Flags: Fragment;	32.20	236	125	5	330	536	2	231	1e-21	105
rs:WP_000681412	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	1e-21	109
rs:WP_018121110	DNA topoisomerase I [Corynebacterium propinquum].	25.75	563	326	23	1	510	1	524	1e-21	110
rs:WP_031372129	DNA topoisomerase I [Lysobacter antibioticus].	23.69	591	351	20	7	563	6	530	1e-21	109
rs:WP_009496920	DNA topoisomerase I [Campylobacter showae].	27.46	437	277	13	89	505	59	475	1e-21	109
rs:WP_000681454	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	1e-21	109
rs:WP_014002039	DNA topoisomerase I [Acidithiobacillus caldus].	25.37	540	311	18	7	505	6	494	1e-21	109
rs:WP_034842450	DNA topoisomerase I [[Clostridium] cellulosi].	25.57	575	330	24	7	553	6	510	1e-21	109
rs:WP_021625049	DNA topoisomerase [Atopobium sp. oral taxon 810].	22.61	513	347	16	65	563	109	585	2e-21	109
rs:WP_001840612	DNA topoisomerase III, partial [Salmonella enterica].	30.69	202	132	3	356	552	18	216	2e-21	105
tr:D7WBB2_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.87	579	342	21	5	544	24	548	2e-21	109
rs:WP_013854176	DNA topoisomerase I [Lactobacillus kefiranofaciens].	25.00	524	316	18	7	505	24	495	2e-21	109
rs:WP_000681472	DNA topoisomerase I [Helicobacter pylori].	28.06	449	259	16	89	505	59	475	2e-21	109
rs:WP_002350895	DNA topoisomerase, partial [Enterococcus faecium].	28.02	364	239	11	52	406	1	350	2e-21	106
rs:WP_010623475	DNA topoisomerase I [Lactobacillus versmoldensis].	26.07	583	322	22	2	553	3	507	2e-21	109
rs:WP_018195577	hypothetical protein [Candidatus Fervidibacter sacchari].	24.13	688	354	28	7	603	34	644	2e-21	109
tr:K1ZG32_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.90	556	310	22	7	514	22	523	2e-21	109
rs:WP_021175304	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	2e-21	109
rs:WP_016381346	DNA topoisomerase I, partial [Lactobacillus paracasei].	27.06	510	297	20	1	486	1	459	2e-21	107
rs:WP_000681410	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	2e-21	109
rs:WP_033764451	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	2e-21	109
rs:WP_004869654	DNA topoisomerase I [Acidithiobacillus caldus].	25.56	540	310	18	7	505	6	494	2e-21	109
rs:WP_038272057	DNA topoisomerase I [Xylella fastidiosa].	26.05	595	332	22	7	563	6	530	2e-21	109
rs:WP_000681480	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	2e-21	109
rs:WP_000681463	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	2e-21	109
tr:X2H807_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	35.35	198	121	6	199	391	19	214	2e-21	103
rs:WP_045655781	DNA topoisomerase I [Hyphomonadaceae bacterium BRH_c29].	25.95	528	313	21	7	505	4	482	2e-21	109
rs:WP_013533917	DNA topoisomerase I [Pseudoxanthomonas suwonensis].	25.13	593	340	21	7	563	6	530	2e-21	109
rs:WP_019183580	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.13	589	346	18	7	563	6	531	2e-21	109
rs:WP_041147928	DNA topoisomerase I [Sulfuricurvum sp. PC08-66].	26.64	533	296	18	7	505	5	476	2e-21	109
tr:K2A4J6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.89	519	327	17	7	504	6	477	2e-21	108
rs:WP_032818446	DNA topoisomerase I [Oenococcus oeni].	25.52	533	299	20	7	504	12	481	2e-21	108
rs:WP_031552912	DNA topoisomerase I [Oribacterium sp. FC2011].	25.33	525	320	20	3	505	2	476	2e-21	108
rs:WP_000681527	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	2e-21	109
rs:WP_033750475	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	2e-21	109
rs:WP_000681526	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	2e-21	109
rs:WP_019177234	hypothetical protein [Methanomassiliicoccus luminyensis].	24.45	634	379	24	2	607	14	575	2e-21	109
rs:WP_005248729	DNA topoisomerase I [Acinetobacter sp. CIP 51.11].	25.46	538	315	21	80	581	46	533	2e-21	109
rs:WP_046272835	DNA topoisomerase I [Stenotrophomonas maltophilia].	25.13	589	346	18	7	563	6	531	2e-21	109
rs:WP_001956342	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	16	89	505	59	475	2e-21	109
rs:WP_000681452	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	2e-21	109
rs:WP_042667972	DNA topoisomerase I [Desulfurococcus amylolyticus].	25.10	510	326	15	110	599	110	583	2e-21	108
rs:WP_011940495	DNA topoisomerase I [Geobacter uraniireducens].	26.68	536	305	20	7	505	6	490	2e-21	109
rs:WP_033619145	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	16	89	505	59	475	2e-21	108
rs:WP_018873178	DNA topoisomerase I [Thioalkalivibrio sp. ALJ16].	25.70	537	313	21	7	505	6	494	2e-21	109
rs:WP_041269879	DNA topoisomerase III, partial [Geobacillus sp. WCH70].	26.64	304	203	8	4	300	1	291	2e-21	105
rs:WP_010340683	DNA topoisomerase I [Xanthomonas sacchari].	25.51	588	344	20	7	563	6	530	2e-21	109
rs:WP_024395842	DNA topoisomerase I [Streptococcus suis].	24.18	521	319	17	7	504	18	485	2e-21	108
rs:WP_000681459	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	2e-21	108
rs:WP_021173223	DNA topoisomerase I [Helicobacter pylori].	28.06	449	259	16	89	505	59	475	2e-21	108
rs:WP_000681443	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	2e-21	108
rs:WP_017909761	DNA topoisomerase I [Xanthomonas sp. SHU199].	25.51	588	344	20	7	563	6	530	2e-21	109
rs:WP_036294629	hypothetical protein, partial [Methylobacter whittenburyi].	25.53	517	287	24	29	504	14	473	2e-21	108
rs:WP_002350831	toprim domain protein, partial [Enterococcus faecium].	32.46	228	137	8	5	225	3	220	2e-21	103
rs:WP_012635699	DNA topoisomerase I [Halothermothrix orenii].	23.10	632	391	22	2	607	5	567	2e-21	108
rs:WP_033768970	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	17	89	505	59	475	2e-21	108
rs:WP_024368809	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	2e-21	108
rs:WP_000681458	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	2e-21	108
rs:WP_001993203	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	40	456	2e-21	108
rs:WP_000681476	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	16	89	505	59	475	2e-21	108
rs:WP_042630303	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	16	89	505	59	475	2e-21	108
rs:WP_012608703	DNA topoisomerase I [Desulfurococcus kamchatkensis].	25.10	510	326	15	110	599	115	588	2e-21	108
rs:WP_033122603	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	17	89	505	59	475	2e-21	108
rs:WP_022972837	DNA topoisomerase I, partial [Xanthomonas sp. M97].	24.83	592	343	21	7	563	6	530	2e-21	108
rs:WP_042713119	DNA topoisomerase III, partial [Klebsiella cf. planticola B43].	32.61	184	116	3	374	552	6	186	2e-21	104
rs:WP_005679476	DNA topoisomerase III [Bacteroides caccae].	23.05	551	356	18	4	531	1	506	2e-21	108
rs:WP_042749308	DNA topoisomerase I, partial [Lactobacillus gasseri].	25.90	525	309	20	7	505	7	477	2e-21	108
rs:WP_017281509	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	2e-21	108
tr:V2LGS5_SALET	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESJ51281.1};	31.25	192	124	3	366	552	2	190	2e-21	105
rs:WP_009650966	DNA topoisomerase I [Campylobacter sp. FOBRC14].	25.34	517	322	17	7	505	5	475	2e-21	108
rs:WP_017925209	DNA topoisomerase I [Thioalkalivibrio sp. HL-Eb18].	26.38	542	303	24	7	505	6	494	2e-21	108
rs:WP_000179632	DNA topoisomerase I [Streptococcus pneumoniae].	25.05	527	306	20	7	504	17	483	2e-21	108
rs:WP_029689622	DNA topoisomerase I [Streptococcus infantis].	24.42	520	316	17	8	504	1	466	3e-21	108
rs:WP_003776900	DNA topoisomerase I [Alloiococcus otitis].	24.72	542	308	21	1	505	1	479	3e-21	108
rs:WP_000681442	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	16	89	505	59	475	3e-21	108
rs:WP_021301973	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	3e-21	108
rs:WP_037358086	DNA topoisomerase I [Selenomonas sp. oral taxon 892].	25.62	609	340	29	7	580	33	563	3e-21	108
sp:TOP1_XYLFA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.80	593	336	22	7	563	6	530	3e-21	108
rs:WP_000681494	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	3e-21	108
tr:U4TCR0_PISSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.55	501	300	16	44	505	1	467	3e-21	108
rs:WP_003647374	DNA topoisomerase I [Lactobacillus gasseri].	25.90	525	309	20	7	505	12	482	3e-21	108
tr:A0A0D5LX21_ACIBA	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AJY48480.1};	25.65	538	314	21	80	581	46	533	3e-21	108
rs:WP_044145861	DNA topoisomerase, partial [Enterococcus faecium].	29.37	303	191	8	278	563	54	350	3e-21	107
tr:U2KLI8_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.62	609	340	29	7	580	47	577	3e-21	108
rs:WP_019627543	DNA topoisomerase I [Thioalkalivibrio sp. AKL10].	26.25	541	305	23	7	505	6	494	3e-21	108
rs:WP_022378698	DNA topoisomerase type IA central domain protein [Cryptobacterium sp. CAG:338].	23.09	550	362	16	65	597	107	612	3e-21	108
rs:WP_033753531	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	3e-21	108
rs:WP_045773382	DNA topoisomerase I [Streptococcus sanguinis].	24.67	523	313	18	7	504	16	482	3e-21	108
rs:WP_017282916	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	3e-21	108
rs:WP_000681528	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	3e-21	108
rs:WP_000681481	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	3e-21	108
rs:WP_022283279	DNA topoisomerase [Clostridium sp. CAG:417].	24.48	629	372	25	7	606	6	560	3e-21	108
rs:WP_017291142	hypothetical protein [Leptolyngbya boryana].	25.49	463	281	14	91	516	66	501	3e-21	108
rs:WP_010508168	DNA topoisomerase I [Komagataeibacter europaeus].	26.13	555	305	25	7	510	5	505	3e-21	108
rs:WP_000179676	DNA topoisomerase I [Streptococcus oralis].	24.42	520	318	17	7	504	17	483	3e-21	108
rs:WP_017113416	hypothetical protein [Xanthomonas campestris].	26.27	316	217	8	8	322	5	305	3e-21	105
rs:WP_009106276	DNA topoisomerase I [Desulfovibrio sp. U5L].	26.78	422	261	16	107	505	75	471	3e-21	108
rs:WP_012983639	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	25.51	537	314	21	7	505	6	494	3e-21	108
tr:D4S8C7_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.57	635	362	27	7	602	45	601	3e-21	108
rs:WP_040571153	DNA topoisomerase I [Selenomonas noxia].	24.57	635	362	27	7	602	34	590	3e-21	108
rs:WP_019625965	DNA topoisomerase I [Thioalkalivibrio sp. ALJT].	25.87	549	308	23	7	505	6	505	3e-21	108
rs:WP_000681409	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	3e-21	108
rs:WP_003648735	DNA topoisomerase I [Lactobacillus gasseri].	25.90	525	309	20	7	505	12	482	3e-21	108
rs:WP_008287467	DNA topoisomerase I [Hydrogenivirga sp. 128-5-R1-1].	25.37	615	352	26	7	603	4	529	3e-21	107
rs:WP_013841888	DNA topoisomerase I [Desulfotomaculum ruminis].	25.04	615	353	25	3	584	2	541	3e-21	108
rs:WP_047250598	DNA topoisomerase I [Thioalkalivibrio versutus].	26.44	537	309	22	7	505	6	494	3e-21	108
rs:WP_023591798	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	17	89	505	59	475	3e-21	108
rs:WP_015643269	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	3e-21	108
rs:WP_025276614	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	3e-21	108
rs:WP_041963169	DNA topoisomerase I [Sulfurospirillum cavolei].	25.00	520	320	18	7	505	9	479	3e-21	108
rs:WP_013553114	DNA topoisomerase I [Nitratifractor salsuginis].	25.72	521	315	18	7	505	5	475	3e-21	108
rs:WP_018135954	DNA topoisomerase I [Campylobacter curvus].	25.53	517	321	17	7	505	5	475	3e-21	108
rs:WP_001924354	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	16	89	505	59	475	3e-21	108
rs:WP_021962295	DNA topoisomerase [Mycoplasma sp. CAG:877].	24.28	626	375	21	7	606	6	558	3e-21	108
rs:WP_040965890	DNA topoisomerase I [Erythrobacter vulgaris].	26.82	548	292	25	7	510	4	486	3e-21	108
rs:WP_018868630	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	25.70	537	313	21	7	505	6	494	3e-21	108
rs:WP_018862529	DNA topoisomerase I [Thioalkalivibrio sp. ALJ3].	25.70	537	313	21	7	505	6	494	3e-21	108
rs:WP_015645546	DNA topoisomerase I [Helicobacter pylori].	28.25	439	271	14	89	505	59	475	3e-21	108
rs:WP_003651155	DNA topoisomerase I [Lactobacillus gasseri].	25.90	525	309	20	7	505	12	482	3e-21	108
rs:WP_018993201	DNA topoisomerase I [Thioalkalivibrio sp. ALgr1].	25.51	537	314	21	7	505	6	494	3e-21	108
rs:WP_018017365	DNA topoisomerase I [Corynebacterium capitovis].	25.00	544	324	20	5	505	7	509	3e-21	108
rs:WP_000681486	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	3e-21	108
rs:WP_000681484	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	3e-21	108
rs:WP_000681400	DNA topoisomerase I [Helicobacter pylori].	27.03	492	282	19	51	505	24	475	3e-21	108
rs:WP_028770836	DNA topoisomerase I [Silanimonas lenta].	24.60	618	362	24	7	586	6	557	3e-21	108
tr:F0H7Y1_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EGC86078.1};	26.82	343	216	11	203	531	1	322	3e-21	107
rs:WP_033756196	DNA topoisomerase I [Helicobacter pylori].	28.16	451	256	17	89	505	59	475	3e-21	108
rs:WP_021308843	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	3e-21	108
tr:A0A080LRY5_9PROT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.25	389	223	14	202	550	15	383	3e-21	108
rs:WP_039061692	DNA topoisomerase III, partial [Shigella flexneri].	32.18	261	151	7	287	525	3	259	3e-21	103
rs:WP_004253452	DNA topoisomerase I [Streptococcus mitis].	24.52	522	315	18	7	504	17	483	3e-21	108
rs:WP_034963909	DNA topoisomerase I [Campylobacter hyointestinalis].	26.09	437	283	12	89	505	59	475	3e-21	108
rs:WP_000681485	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	3e-21	108
rs:WP_024116083	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	3e-21	108
rs:WP_001965050	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	16	89	505	59	475	3e-21	108
rs:WP_001921627	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	3e-21	108
rs:WP_000681399	DNA topoisomerase I [Helicobacter pylori].	27.03	492	282	19	51	505	24	475	3e-21	108
rs:WP_019090899	DNA topoisomerase I [Komagataeibacter europaeus].	26.13	555	305	25	7	510	5	505	3e-21	108
rs:WP_040410425	DNA topoisomerase I [[Clostridium] hiranonis].	24.84	632	374	26	7	607	6	567	3e-21	108
rs:WP_008283969	DNA topoisomerase I [gamma proteobacterium HTCC5015].	25.69	541	308	22	7	505	6	494	4e-21	108
rs:WP_033683782	DNA topoisomerase I [Streptococcus mitis].	25.24	527	305	20	7	504	17	483	4e-21	108
rs:WP_018951810	DNA topoisomerase I [Thioalkalivibrio sp. AKL12].	26.44	537	309	22	7	505	6	494	4e-21	108
rs:WP_012636779	DNA topoisomerase I [Thioalkalivibrio sulfidiphilus].	25.70	533	318	19	7	505	6	494	4e-21	108
rs:WP_001678913	DNA topoisomerase III, partial [Salmonella enterica].	26.84	313	210	9	8	310	5	308	4e-21	104
tr:A0A0D6PWM0_KOMEU	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN95180.1};	26.13	555	305	25	7	510	5	505	4e-21	108
sp:TOP1_HELPY	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	27.62	449	261	16	89	505	59	475	4e-21	108
rs:WP_032331321	DNA topoisomerase III, partial [Escherichia coli].	30.69	202	132	3	356	552	1	199	4e-21	104
rs:WP_023458044	DNA topoisomerase I [Asticcacaulis sp. AC466].	25.92	544	319	23	4	510	1	497	4e-21	108
rs:WP_033776699	DNA topoisomerase I [Helicobacter pylori].	28.00	450	258	18	89	505	59	475	4e-21	108
rs:WP_015428573	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	4e-21	108
rs:WP_000681478	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	4e-21	108
rs:WP_000681498	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	4e-21	108
rs:WP_000681418	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	4e-21	108
rs:WP_006145648	DNA topoisomerase I [Streptococcus peroris].	24.90	522	313	19	7	504	17	483	4e-21	108
rs:WP_042105386	DNA topoisomerase I [Parachlamydiaceae bacterium HS-T3].	25.69	541	320	21	3	505	2	498	4e-21	108
rs:WP_033587723	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	4e-21	108
rs:WP_000681483	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	4e-21	108
rs:WP_000681417	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	4e-21	108
rs:WP_042633138	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	4e-21	108
rs:WP_033789637	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	16	89	505	59	475	4e-21	108
rs:WP_013221847	DNA topoisomerase I [Nitrosococcus watsonii].	24.68	555	311	19	3	504	2	502	4e-21	108
rs:WP_031796378	DNA topoisomerase III, partial [Staphylococcus aureus].	32.46	228	141	7	5	226	3	223	4e-21	103
rs:WP_024650439	hypothetical protein [Pseudomonas syringae].	26.35	539	291	22	5	505	3	473	4e-21	108
rs:WP_029200664	DNA topoisomerase I [Oribacterium sp. NK2B42].	25.52	525	319	20	3	505	2	476	4e-21	108
rs:WP_010642515	DNA topoisomerase I [Acidithiobacillus thiooxidans].	26.20	458	284	17	81	505	49	485	4e-21	108
rs:WP_040316801	DNA topoisomerase I [Actinomyces europaeus].	24.56	566	326	19	1	505	1	526	4e-21	108
rs:WP_020088643	DNA topoisomerase I [Lactobacillus parabrevis].	24.62	524	318	20	7	505	22	493	4e-21	108
rs:WP_036757601	DNA topoisomerase I [Peptoniphilus lacrimalis].	24.81	520	316	18	7	504	17	483	4e-21	108
rs:WP_035012822	DNA topoisomerase I [Catenovulum agarivorans].	27.17	460	285	16	69	505	72	504	4e-21	108
tr:E8JTB1_STRCR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.62	520	317	18	7	504	19	485	4e-21	108
tr:B6FZ87_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.60	630	378	25	7	607	12	573	4e-21	108
rs:WP_000681479	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	4e-21	108
rs:WP_000681415	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	4e-21	108
rs:WP_009554367	DNA topoisomerase I [Lactobacillus saerimneri].	25.81	523	312	21	7	505	16	486	4e-21	108
rs:WP_027149269	DNA topoisomerase I [Methylobacter tundripaludum].	25.64	589	339	20	7	562	6	528	4e-21	108
rs:WP_033614663	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	16	89	505	59	475	4e-21	108
rs:WP_000681416	DNA topoisomerase I [Helicobacter pylori].	27.39	449	262	16	89	505	59	475	4e-21	108
rs:WP_045497387	DNA topoisomerase I [Streptococcus cristatus].	24.62	520	317	18	7	504	16	482	4e-21	108
rs:WP_019084977	DNA topoisomerase I [Komagataeibacter europaeus].	26.13	555	305	25	7	510	5	505	4e-21	108
rs:WP_005591982	DNA topoisomerase I [Streptococcus cristatus].	24.62	520	317	18	7	504	16	482	4e-21	108
tr:S2VVK6_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.64	560	321	19	7	505	20	539	4e-21	108
rs:WP_024116767	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	17	89	505	59	475	4e-21	108
rs:WP_019558996	DNA topoisomerase I [Thioalkalivibrio sp. ALE12].	25.88	537	312	22	7	505	6	494	4e-21	108
rs:WP_036503429	DNA topoisomerase I [Nitrosococcus oceani].	24.06	557	314	16	3	505	2	503	4e-21	108
rs:WP_007144187	DNA topoisomerase I [Methylophaga aminisulfidivorans].	24.63	536	320	16	7	505	6	494	4e-21	108
rs:WP_025287779	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	4e-21	107
rs:WP_028383191	DNA topoisomerase I [Legionella moravica].	26.54	535	311	15	7	505	6	494	5e-21	108
rs:WP_025385032	DNA topoisomerase I [Legionella oakridgensis].	27.09	539	302	20	7	505	6	493	5e-21	108
rs:WP_025222407	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	5e-21	107
rs:WP_042942923	DNA topoisomerase III, partial [Klebsiella pneumoniae].	33.33	213	133	6	203	408	1	211	5e-21	102
rs:WP_033601513	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	16	89	505	59	475	5e-21	107
rs:WP_033793824	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	16	89	505	59	475	5e-21	107
rs:WP_000681453	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	17	89	505	59	475	5e-21	107
tr:S4NK75_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.38	303	189	10	279	563	15	307	5e-21	104
rs:WP_034840251	DNA topoisomerase I [[Clostridium] cellulosi].	24.55	607	356	25	7	583	5	539	5e-21	107
rs:WP_045085262	DNA topoisomerase I [[Clostridium] cellulosi].	24.55	607	356	25	7	583	5	539	5e-21	107
rs:WP_009731066	DNA topoisomerase 1 [Streptococcus sp. F0442].	24.09	523	316	17	7	504	15	481	5e-21	107
rs:WP_000681477	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	17	89	505	59	475	5e-21	107
rs:WP_018876614	DNA topoisomerase I [Thioalkalivibrio sp. ALE31].	25.88	537	312	22	7	505	6	494	5e-21	108
tr:W7QXB4_9ALTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.17	460	285	16	69	505	19	451	5e-21	108
rs:WP_034815084	DNA topoisomerase I [Exiguobacterium alkaliphilum].	24.49	641	370	22	7	607	6	572	5e-21	107
rs:WP_004636185	DNA topoisomerase I [Dolosigranulum pigrum].	24.24	528	315	20	7	505	7	478	5e-21	107
rs:WP_025366675	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	17	89	505	59	475	5e-21	107
rs:WP_023171016	DNA topoisomerase III, partial [Salmonella enterica].	31.07	280	167	7	287	544	21	296	5e-21	106
rs:WP_033584725	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	16	89	505	59	475	5e-21	107
rs:WP_031623077	DNA topoisomerase III, partial [Salmonella enterica].	31.07	280	167	7	287	544	20	295	5e-21	106
rs:WP_018878614	DNA topoisomerase I [Thioalkalivibrio sp. ALE28].	25.88	537	312	22	7	505	6	494	5e-21	108
rs:WP_008436951	DNA topoisomerase I [Rhodanobacter thiooxydans].	25.50	545	310	20	7	505	6	500	5e-21	108
rs:WP_019584255	DNA topoisomerase I [Thioalkalivibrio sp. ALE16].	25.88	537	312	22	7	505	6	494	5e-21	108
rs:WP_043951828	DNA topoisomerase, partial [Enterococcus faecium].	32.46	228	137	8	5	225	33	250	5e-21	103
rs:WP_012283267	DNA topoisomerase I [Heliobacterium modesticaldum].	25.84	565	322	23	1	539	1	494	5e-21	107
rs:WP_014343006	DNA topoisomerase III, partial [Klebsiella pneumoniae].	32.22	180	114	3	374	548	9	185	5e-21	103
rs:WP_000179670	DNA topoisomerase I [Streptococcus oralis].	24.42	520	318	17	7	504	17	483	5e-21	107
tr:I6F9D3_SHIBO	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EIQ52875.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EIQ52875.1};	28.51	249	169	4	69	314	1	243	5e-21	103
rs:WP_041151453	DNA topoisomerase I [Sulfurovum sp. FS08-3].	25.12	430	280	13	97	505	69	477	5e-21	107
tr:A0A061PB57_9BACL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.22	332	192	11	278	593	20	324	5e-21	106
rs:WP_002953849	DNA topoisomerase I [Campylobacter showae].	27.00	437	279	13	89	505	59	475	5e-21	107
rs:WP_033603498	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	16	89	505	59	475	6e-21	107
rs:WP_033617385	topoisomerase I, partial [Lactobacillus plantarum].	28.21	312	198	11	174	472	4	302	6e-21	104
rs:WP_000681450	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	17	89	505	59	475	6e-21	107
tr:A0A090RC47_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.71	254	167	6	110	359	3	251	6e-21	103
rs:WP_018882556	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	25.88	537	312	22	7	505	6	494	6e-21	107
rs:WP_027826532	DNA topoisomerase I [Lactobacillus saerimneri].	25.81	523	312	21	7	505	16	486	6e-21	107
rs:WP_041971679	DNA topoisomerase I [Geobacter sp. OR-1].	25.88	537	308	21	7	505	6	490	6e-21	107
rs:WP_000179644	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	6e-21	107
rs:WP_018286108	hypothetical protein [zeta proteobacterium SCGC AB-137-I08].	26.29	445	270	14	97	505	66	488	6e-21	107
rs:WP_000179622	DNA topoisomerase I [Streptococcus oralis].	24.42	520	318	17	7	504	17	483	6e-21	107
rs:WP_003526250	hypothetical protein, partial [[Clostridium] clostridioforme].	26.90	290	185	7	277	549	1	280	6e-21	105
rs:WP_029662309	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	6e-21	107
gp:CP002165_604	DNA topoisomerase I [Xylella fastidiosa subsp. fastidiosa GB514]	25.59	598	341	22	7	568	6	535	6e-21	107
rs:WP_008441419	DNA topoisomerase I, archaeal [Thermoplasmatales archaeon SCGC AB-539-N05].	22.92	576	367	17	7	566	4	518	6e-21	107
rs:WP_019029394	topoisomerase I [Colwellia piezophila].	25.92	544	313	20	7	505	6	504	6e-21	107
rs:WP_000681471	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	17	89	505	59	475	6e-21	107
tr:F2QD08_STROU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.42	520	318	17	7	504	17	483	6e-21	107
rs:WP_044020637	DNA topoisomerase I [Streptococcus sp. VT 162].	24.42	520	318	17	7	504	17	483	6e-21	107
rs:WP_040161716	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	17	89	505	59	475	6e-21	107
rs:WP_000179671	DNA topoisomerase I [Streptococcus oralis].	24.42	520	318	17	7	504	17	483	6e-21	107
rs:WP_000179619	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	6e-21	107
rs:WP_022850531	DNA topoisomerase [Geovibrio sp. L21-Ace-BES].	24.72	538	328	20	7	512	6	498	6e-21	107
rs:WP_041572324	DNA topoisomerase I, partial [Xylella fastidiosa].	25.59	598	341	22	7	568	6	535	6e-21	107
rs:WP_000681482	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	6e-21	107
rs:WP_021735919	DNA topoisomerase I [Coriobacteriaceae bacterium BV3Ac1].	22.27	512	350	15	65	563	109	585	6e-21	107
rs:WP_023944170	DNA topoisomerase I [Streptococcus mitis].	25.05	527	306	20	7	504	17	483	7e-21	107
rs:WP_004086454	DNA topoisomerase I [Xylella fastidiosa].	25.59	598	341	22	7	568	6	535	7e-21	107
tr:W4UVJ6_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.10	554	352	20	4	531	11	516	7e-21	107
rs:WP_024949339	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	7e-21	107
rs:WP_000681519	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	17	89	505	59	475	7e-21	107
rs:WP_031228895	DNA topoisomerase III, partial [Salmonella enterica].	28.77	292	183	9	287	557	17	304	7e-21	104
rs:WP_042902188	DNA topoisomerase I [Streptococcus oralis].	24.42	520	318	17	7	504	17	483	7e-21	107
rs:WP_042767797	DNA topoisomerase I [Streptococcus sp. DBCMS].	24.42	520	318	17	7	504	17	483	7e-21	107
rs:WP_000179629	DNA topoisomerase I [Streptococcus mitis].	24.42	520	318	17	7	504	17	483	7e-21	107
tr:B2I572_XYLF2	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.80	306	205	7	43	336	16	314	7e-21	103
rs:WP_000681492	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	16	89	505	59	475	7e-21	107
rs:WP_014404407	DNA topoisomerase I [Frateuria aurantia].	25.97	543	310	17	7	505	6	500	7e-21	107
rs:WP_029567813	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	17	89	505	59	475	7e-21	107
rs:WP_037993304	DNA topoisomerase III, partial [Tannerella sp. oral taxon BU063].	26.59	331	210	12	8	332	3	306	7e-21	103
rs:WP_007516861	DNA topoisomerase I [Streptococcus tigurinus].	24.42	520	318	17	7	504	17	483	7e-21	107
sp:TOP1_XYLFT	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.59	598	341	22	7	568	6	535	7e-21	107
rs:WP_000179655	DNA topoisomerase I [Streptococcus mitis].	25.05	527	306	20	7	504	17	483	7e-21	107
rs:WP_031586825	DNA topoisomerase I [Selenomonas bovis].	25.00	628	365	28	5	594	39	598	7e-21	107
tr:Q2B125_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EAR63544.1};	31.03	232	142	7	7	236	5	220	7e-21	103
rs:WP_024773959	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	7e-21	107
rs:WP_024751547	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	7e-21	107
rs:WP_000681449	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	7e-21	107
rs:WP_000179669	DNA topoisomerase I [Streptococcus sp. oral taxon 071].	24.42	520	318	17	7	504	17	483	7e-21	107
rs:WP_016465755	DNA topoisomerase 1 [Streptococcus sp. HPH0090].	24.62	520	317	18	7	504	17	483	7e-21	107
rs:WP_000681411	DNA topoisomerase I [Helicobacter pylori].	27.84	449	260	16	89	505	59	475	7e-21	107
rs:WP_011815111	DNA topoisomerase I [Halorhodospira halophila].	24.64	560	311	20	7	505	6	515	7e-21	107
rs:WP_000681455	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	7e-21	107
rs:WP_044498954	DNA topoisomerase I [Pseudomonas sp. 12M76_air].	23.77	530	318	18	5	505	3	475	7e-21	107
rs:WP_000681469	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	7e-21	107
tr:F9Q4Y2_STROR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.53	521	307	20	9	504	1	465	8e-21	106
tr:S3JEW5_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	33.33	213	133	6	203	408	1	211	8e-21	102
rs:WP_034549947	hypothetical protein, partial [Helicobacter fennelliae].	26.02	488	301	17	47	505	20	476	8e-21	107
tr:K1S1X7_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EKC54717.1};	24.32	629	373	25	7	606	6	560	8e-21	107
rs:WP_000179657	DNA topoisomerase I [Streptococcus mitis].	25.05	527	306	20	7	504	17	483	8e-21	107
rs:WP_000179682	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	8e-21	107
rs:WP_045617272	DNA topoisomerase I [Streptococcus mitis].	24.42	520	318	17	7	504	17	483	8e-21	107
rs:WP_027700506	DNA topoisomerase I [Xylella fastidiosa].	25.59	598	341	22	7	568	6	535	8e-21	107
tr:A0A031LP74_9CREN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.89	540	346	20	5	531	9	496	8e-21	107
rs:WP_018144652	DNA topoisomerase I [Thioalkalivibrio sp. AKL6].	26.44	537	309	22	7	505	6	494	8e-21	107
rs:WP_044163783	DNA topoisomerase I [Bacteroides reticulotermitis].	23.10	554	352	20	4	531	1	506	8e-21	106
rs:WP_014162685	DNA topoisomerase I [Thermovirga lienii].	25.70	533	309	19	5	504	16	494	8e-21	107
rs:WP_045759471	DNA topoisomerase I [Streptococcus parasanguinis].	24.38	525	312	19	7	504	15	481	8e-21	107
tr:T1CRF0_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.02	488	301	17	47	505	20	476	8e-21	107
rs:WP_010021434	DNA topoisomerase I [Lactobacillus fructivorans].	26.05	522	311	19	7	504	24	494	8e-21	107
rs:WP_000681401	DNA topoisomerase I [Helicobacter pylori].	27.49	451	259	16	89	505	59	475	8e-21	107
rs:WP_000681523	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	17	89	505	59	475	8e-21	107
rs:WP_000179653	DNA topoisomerase I [Streptococcus mitis].	25.05	527	306	20	7	504	17	483	8e-21	107
rs:WP_024869872	DNA topoisomerase I [Pseudoxanthomonas suwonensis].	25.51	541	311	19	7	505	6	496	9e-21	107
rs:WP_039142858	DNA topoisomerase I [Lactobacillus fructivorans].	26.05	522	311	19	7	504	28	498	9e-21	107
rs:WP_038229912	DNA topoisomerase I [Xylella fastidiosa].	25.59	598	341	22	7	568	6	535	9e-21	107
rs:WP_033629621	DNA topoisomerase I [Streptococcus oralis].	24.42	520	318	17	7	504	17	483	9e-21	107
rs:WP_026938559	DNA topoisomerase I [Helicobacter pylori].	27.49	451	259	16	89	505	59	475	9e-21	107
rs:WP_000179667	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.42	520	318	17	7	504	17	483	9e-21	107
rs:WP_029362891	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	9e-21	107
rs:WP_000681474	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	9e-21	107
rs:WP_000179668	DNA topoisomerase I [Streptococcus sp. oral taxon 058].	24.42	520	318	17	7	504	17	483	9e-21	107
tr:R2NN74_9ENTE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOH73452.1};	29.08	251	162	7	5	248	3	244	9e-21	102
rs:WP_000681470	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	9e-21	107
rs:WP_008315788	DNA topoisomerase 1 [Wohlfahrtiimonas chitiniclastica].	25.97	543	309	19	3	504	2	492	1e-20	107
rs:WP_037910128	DNA topoisomerase I [Sulfitobacter mediterraneus].	25.87	549	307	23	4	510	1	491	1e-20	107
rs:WP_028919946	DNA topoisomerase I [Pseudoxanthomonas suwonensis].	25.51	541	311	19	7	505	6	496	1e-20	107
tr:A0A060HA84_XYLFS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.80	306	205	7	43	336	16	314	1e-20	103
rs:WP_033582285	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	1e-20	107
rs:WP_009725216	DNA topoisomerase I [Methylophaga lonarensis].	24.49	543	311	18	7	505	6	493	1e-20	107
rs:WP_033585366	DNA topoisomerase I [Streptococcus sp. SR1].	24.42	520	318	17	7	504	17	483	1e-20	107
tr:R9IKQ1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.94	409	261	11	147	539	6	384	1e-20	106
rs:WP_003013852	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	17	89	505	59	475	1e-20	107
rs:WP_028928297	DNA topoisomerase I [Pseudoxanthomonas suwonensis].	25.51	541	311	19	7	505	6	496	1e-20	107
rs:WP_023526886	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	17	89	505	59	475	1e-20	107
rs:WP_000681487	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	1e-20	107
rs:WP_000681464	DNA topoisomerase I [Helicobacter pylori].	27.94	451	257	16	89	505	59	475	1e-20	107
rs:WP_007403904	MULTISPECIES: DNA topoisomerase I [Sphingomonas].	26.67	525	305	23	7	505	4	474	1e-20	107
rs:WP_035431967	DNA topoisomerase [Atopobium parvulum].	22.70	511	345	16	65	563	109	581	1e-20	107
rs:WP_000179673	DNA topoisomerase I [Streptococcus mitis].	24.86	527	307	20	7	504	17	483	1e-20	106
tr:J6QSP7_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJX60598.1}; Flags: Fragment;	32.30	226	136	8	5	223	3	218	1e-20	101
rs:WP_033771067	DNA topoisomerase I [Helicobacter pylori].	27.38	442	271	14	89	505	59	475	1e-20	107
rs:WP_001919591	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	1e-20	107
rs:WP_000179656	DNA topoisomerase I [Streptococcus pseudopneumoniae].	25.05	527	306	20	7	504	17	483	1e-20	106
rs:WP_033680386	DNA topoisomerase I [Streptococcus mitis].	25.24	527	305	20	7	504	17	483	1e-20	106
rs:WP_020199469	hypothetical protein [Sulfolobales archaeon Acd1].	25.80	566	341	22	5	548	10	518	1e-20	106
rs:WP_013468922	DNA topoisomerase I [Helicobacter felis].	24.46	466	288	13	85	505	58	504	1e-20	107
tr:G0QFA3_NANS0	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.08	559	342	22	5	532	4	505	1e-20	106
rs:WP_044811425	DNA topoisomerase I [Streptococcus pneumoniae].	25.05	527	306	20	7	504	17	483	1e-20	106
rs:WP_029919888	DNA topoisomerase I [Nevskia soli].	26.21	538	308	19	7	504	6	494	1e-20	107
rs:WP_000179666	DNA topoisomerase I [Streptococcus oralis].	24.42	520	318	17	7	504	17	483	1e-20	106
rs:WP_008213199	toprim domain protein, partial [Lactobacillus parafarraginis].	30.52	249	159	6	5	247	3	243	1e-20	102
rs:WP_021300989	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	17	89	505	59	475	1e-20	106
rs:WP_000179626	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.42	520	318	17	7	504	17	483	1e-20	106
rs:WP_018953624	DNA topoisomerase I [Thioalkalivibrio sp. ALJ17].	25.70	533	318	19	7	505	6	494	1e-20	107
rs:WP_021085359	DNA topoisomerase I [Campylobacter concisus].	26.54	437	281	13	89	505	59	475	1e-20	106
rs:WP_009166274	DNA topoisomerase I [Lactobacillus florum].	25.48	522	314	20	7	504	24	494	1e-20	106
rs:WP_002833092	DNA topoisomerase I [Pediococcus pentosaceus].	25.62	527	309	20	7	505	9	480	1e-20	106
rs:WP_034968372	DNA topoisomerase I [Campylobacter mucosalis].	25.90	444	275	14	89	505	59	475	1e-20	106
rs:WP_000179624	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.42	520	318	17	7	504	17	483	1e-20	106
rs:WP_024525219	DNA topoisomerase I [Lactobacillus brevis].	25.00	528	311	21	7	505	22	493	1e-20	106
rs:WP_000179627	DNA topoisomerase I [Streptococcus mitis].	24.42	520	318	17	7	504	17	483	1e-20	106
rs:WP_043023131	DNA topoisomerase I [Lactobacillus brevis].	25.00	528	311	21	7	505	22	493	1e-20	106
rs:WP_012674102	DNA topoisomerase I [Sulfurihydrogenibium azorense].	23.65	613	360	21	7	593	5	535	1e-20	106
rs:WP_000179628	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.42	520	318	17	7	504	17	483	1e-20	106
rs:WP_032819641	topoisomerase I, partial [Oenococcus oeni].	28.13	327	201	11	200	508	1	311	1e-20	103
rs:WP_000179635	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	1e-20	106
rs:WP_041074035	DNA topoisomerase I [Bacillus sp. OxB-1].	27.51	429	256	16	107	504	77	481	1e-20	106
rs:WP_002349701	toprim domain protein, partial [Enterococcus faecium].	32.74	226	135	8	5	223	3	218	1e-20	101
rs:WP_000179625	DNA topoisomerase I [Streptococcus oralis].	24.42	520	318	17	7	504	17	483	1e-20	106
rs:WP_024325912	DNA topoisomerase I [Thioalkalivibrio sp. AKL19].	26.44	537	309	22	7	505	6	494	1e-20	107
rs:WP_034855894	DNA topoisomerase I [Ignatzschineria larvae].	25.88	541	316	19	3	505	2	495	1e-20	106
rs:WP_012857987	DNA topoisomerase I [Sulfurospirillum deleyianum].	24.95	525	314	17	7	505	9	479	1e-20	106
rs:WP_014806151	DNA topoisomerase I [Anaerobaculum mobile].	25.33	529	316	17	1	504	4	478	1e-20	106
rs:WP_033617937	DNA topoisomerase I [Helicobacter pylori].	27.49	451	259	16	89	505	59	475	1e-20	106
rs:WP_000179654	DNA topoisomerase I [Streptococcus pseudopneumoniae].	25.05	527	306	20	7	504	17	483	1e-20	106
rs:WP_019724267	hypothetical protein, partial [Enterococcus mundtii].	27.37	285	164	10	278	550	47	300	1e-20	105
rs:WP_019593470	DNA topoisomerase I [Thioalkalivibrio sp. ALM2T].	26.44	537	309	22	7	505	6	494	1e-20	106
rs:WP_017284169	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	1e-20	106
rs:WP_035218062	DNA topoisomerase I, partial [Acidithiobacillus thiooxidans].	26.85	447	274	17	89	505	59	482	1e-20	106
sp:TOP1_HELPJ	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	27.72	451	258	16	89	505	59	475	1e-20	106
rs:WP_046920631	DNA topoisomerase I [Lactobacillus ruminis].	25.38	528	309	21	7	505	26	497	1e-20	106
rs:WP_009438447	DNA topoisomerase I [Selenomonas sp. oral taxon 137].	25.94	532	308	22	5	505	26	502	1e-20	106
rs:WP_026147909	DNA topoisomerase I [Robiginitomaculum antarcticum].	25.78	543	307	23	4	505	1	488	1e-20	106
rs:WP_033606327	DNA topoisomerase I [Streptococcus sp. CM6].	24.42	520	318	17	7	504	17	483	1e-20	106
rs:WP_039968868	DNA topoisomerase I [Selenomonas artemidis].	26.18	531	308	22	5	505	26	502	1e-20	106
rs:WP_004362759	hypothetical protein [Prevotella nigrescens].	27.27	341	211	10	4	333	2	316	1e-20	103
rs:WP_018176248	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	26.26	537	310	22	7	505	6	494	1e-20	106
tr:A0A0B4BBE9_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.85	530	304	22	7	505	26	497	1e-20	106
rs:WP_000681462	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	1e-20	106
rs:WP_018650578	DNA topoisomerase I [Thioalkalivibrio sp. ALMg3].	26.26	537	310	22	7	505	6	494	1e-20	106
rs:WP_006152356	DNA topoisomerase I [Streptococcus infantis].	24.95	517	313	18	10	504	2	465	1e-20	106
tr:W4LTG6_9DELT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETX01011.1};	24.93	369	246	10	200	540	1	366	1e-20	105
rs:WP_037349343	DNA topoisomerase I [Selenomonas artemidis].	26.18	531	308	22	5	505	26	502	1e-20	106
rs:WP_009658146	DNA topoisomerase I [Selenomonas sp. FOBRC9].	25.94	532	308	22	5	505	26	502	1e-20	106
rs:WP_013337555	DNA topoisomerase [Vulcanisaeta distributa].	23.51	553	359	21	7	537	7	517	1e-20	106
rs:WP_039847570	DNA topoisomerase III, partial [Pseudomonas amygdali].	30.81	185	116	3	375	549	2	184	1e-20	103
rs:WP_009436399	DNA topoisomerase III [Prevotella sp. oral taxon 473].	28.13	327	182	9	260	539	320	640	1e-20	106
rs:WP_009436399	DNA topoisomerase III [Prevotella sp. oral taxon 473].	29.69	229	140	5	7	225	2	219	4e-17	95.5
rs:WP_046859941	DNA topoisomerase I [Sedimenticola sp. SIP-G1].	25.46	538	313	18	7	505	4	492	1e-20	106
rs:WP_006474388	DNA topoisomerase I [endosymbiont of Tevnia jerichonana].	24.95	533	322	16	7	505	4	492	1e-20	106
rs:WP_040572300	DNA topoisomerase I [Selenomonas flueggei].	26.69	532	300	26	7	505	34	508	1e-20	106
rs:WP_018938918	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	26.26	537	310	22	7	505	6	494	1e-20	106
rs:WP_008543520	toprim domain protein, partial [Sutterella parvirubra].	29.56	318	186	10	5	304	4	301	1e-20	102
rs:WP_045591152	DNA topoisomerase I [Streptococcus mitis].	24.23	520	319	17	7	504	17	483	1e-20	106
rs:WP_021900264	DNA topoisomerase type IA central domain protein [Eggerthella sp. CAG:1427].	22.91	550	363	16	65	597	107	612	1e-20	106
rs:WP_013810225	DNA topoisomerase I [Desulfotomaculum carboxydivorans].	24.07	615	359	22	3	584	7	546	1e-20	106
rs:WP_021306574	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	17	89	505	59	475	1e-20	106
rs:WP_004269684	DNA topoisomerase I [Streptococcus mitis].	24.86	527	307	20	7	504	17	483	2e-20	106
tr:K7HB21_CAEJA	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:CJA21342b};	23.70	540	312	18	5	505	476	954	2e-20	107
rs:WP_019568140	DNA topoisomerase I [Thioalkalivibrio sp. ALMg13-2].	26.26	537	310	22	7	505	6	494	2e-20	106
rs:WP_005964300	DNA topoisomerase I [endosymbiont of Riftia pachyptila].	24.95	533	322	16	7	505	4	492	2e-20	106
rs:WP_018168364	DNA topoisomerase I [Thioalkalivibrio sp. ALMg9].	26.26	537	310	22	7	505	6	494	2e-20	106
tr:K7HB20_CAEJA	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:CJA21342a};	23.70	540	312	18	5	505	476	954	2e-20	107
rs:WP_021303226	DNA topoisomerase I [Helicobacter pylori].	28.09	445	264	15	89	505	59	475	2e-20	106
rs:WP_035435739	DNA topoisomerase [Atopobium sp. BS2].	21.92	511	349	15	65	563	109	581	2e-20	106
rs:WP_021288439	DNA topoisomerase I [Sulfurimonas sp. AST-10].	24.28	523	321	18	7	505	4	475	2e-20	106
rs:WP_036876890	DNA topoisomerase [Prevotella denticola].	29.85	268	162	9	277	531	58	312	2e-20	105
rs:WP_012846247	DNA topoisomerase I [Lactobacillus johnsonii].	25.52	525	311	20	7	505	12	482	2e-20	106
rs:WP_003001546	DNA topoisomerase I [Streptococcus parasanguinis].	24.38	525	312	19	7	504	15	481	2e-20	106
rs:WP_000179645	DNA topoisomerase I [Streptococcus pneumoniae].	25.19	524	309	20	7	504	17	483	2e-20	106
rs:WP_027835164	DNA topoisomerase I [Maritalea myrionectae].	25.89	533	306	20	7	505	4	481	2e-20	106
rs:WP_039209848	DNA topoisomerase, partial [Anaerovibrio lipolyticus].	30.70	228	146	5	8	234	5	221	2e-20	101
rs:WP_012175861	DNA topoisomerase I [Desulfococcus oleovorans].	27.21	544	303	25	7	510	6	496	2e-20	106
tr:E7MZJ2_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.94	532	308	22	5	505	40	516	2e-20	106
rs:WP_014947339	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	106
rs:WP_004644771	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	25.09	538	317	21	80	581	46	533	2e-20	106
tr:C4V2Y3_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.69	532	300	26	7	505	48	522	2e-20	106
rs:WP_046318093	hypothetical protein [Lactobacillus mellifer].	24.14	580	349	20	7	539	4	539	2e-20	106
rs:WP_021153232	DNA topoisomerase I [Streptococcus sp. HSISM1].	24.67	527	308	20	7	504	15	481	2e-20	106
rs:WP_011578289	DNA topoisomerase I [Helicobacter acinonychis].	27.72	451	258	16	89	505	59	475	2e-20	106
rs:WP_043951823	hypothetical protein, partial [Enterococcus faecium].	30.26	304	193	9	5	301	3	294	2e-20	102
rs:WP_000179665	DNA topoisomerase I [Streptococcus oralis].	24.42	520	318	17	7	504	17	483	2e-20	106
rs:WP_000179663	DNA topoisomerase I [Streptococcus mitis].	24.86	527	307	20	7	504	17	483	2e-20	106
rs:WP_015060259	MULTISPECIES: DNA topoisomerase I [environmental samples].	25.24	531	325	19	80	581	46	533	2e-20	106
rs:WP_001844626	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	106
rs:WP_007288449	DNA topoisomerase I [Thermosinus carboxydivorans].	24.57	635	368	25	7	606	6	564	2e-20	106
rs:WP_033874305	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	34.76	164	103	3	292	452	1	163	2e-20	100
rs:WP_003541173	DNA topoisomerase I [Desulfotomaculum nigrificans].	24.07	615	359	22	3	584	7	546	2e-20	106
rs:WP_022406180	DNA topoisomerase [Prevotella sp. CAG:485].	26.40	519	301	17	7	505	5	462	2e-20	106
rs:WP_023599657	DNA topoisomerase I [Lactobacillus johnsonii].	25.33	525	312	20	7	505	12	482	2e-20	105
rs:WP_038052696	DNA topoisomerase I, partial [Thermomonas fusca].	26.69	592	332	24	7	563	6	530	2e-20	106
rs:WP_027846908	DNA topoisomerase I [Mastigocoleus testarum].	25.77	454	276	15	91	504	66	498	2e-20	106
rs:WP_000246896	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	105
rs:WP_000179640	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	105
tr:K7HB22_CAEJA	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:CJA21342c};	23.70	540	312	18	5	505	476	954	2e-20	107
rs:WP_023495199	DNA topoisomerase 1 [Methyloglobulus morosus].	25.21	591	339	21	7	562	6	528	2e-20	106
rs:WP_000179651	DNA topoisomerase I [Streptococcus pneumoniae].	25.19	524	309	20	7	504	17	483	2e-20	105
rs:WP_019553209	hypothetical protein [Propionispira raffinosivorans].	25.65	581	321	26	5	553	8	509	2e-20	106
rs:WP_000681473	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	2e-20	106
rs:WP_000179639	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	105
rs:WP_000179681	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	105
rs:WP_039936927	DNA topoisomerase I [Leptospira terpstrae].	25.32	466	285	18	76	504	23	462	2e-20	105
rs:WP_000179638	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	105
rs:WP_003011242	DNA topoisomerase I [Streptococcus parasanguinis].	24.38	525	312	19	7	504	17	483	2e-20	105
rs:WP_040534196	DNA topoisomerase I [Lactobacillus shenzhenensis].	25.49	612	348	25	7	586	6	541	2e-20	105
tr:D4K6W0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.05	479	290	18	145	590	4	446	2e-20	105
rs:WP_013897831	DNA topoisomerase [Methanosalsum zhilinae].	26.63	507	291	24	75	548	59	517	2e-20	106
rs:WP_033586562	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	2e-20	105
rs:WP_034508749	DNA topoisomerase I [Actinomyces sp. S4-C9].	24.73	566	325	19	1	505	1	526	2e-20	106
tr:U3TRG9_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.55	452	294	15	69	504	68	497	2e-20	105
rs:WP_018378171	DNA topoisomerase I [Streptococcus ovis].	24.09	523	317	18	7	504	18	485	2e-20	105
rs:WP_006148622	DNA topoisomerase I [Streptococcus infantis].	24.62	520	317	18	7	504	17	483	2e-20	105
tr:K2EGY6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.05	511	314	17	7	504	4	458	2e-20	105
rs:WP_000179672	DNA topoisomerase I [Streptococcus mitis].	24.42	520	318	17	7	504	17	483	2e-20	105
rs:WP_000179637	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	105
rs:WP_000179623	DNA topoisomerase I [Streptococcus sp. C300].	24.42	520	318	17	7	504	17	483	2e-20	105
rs:WP_016399457	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	105
rs:WP_009730244	DNA topoisomerase 1 [Streptococcus sp. F0441].	24.42	520	318	17	7	504	17	483	2e-20	105
rs:WP_023488722	DNA topoisomerase [Lactobacillus crispatus].	24.09	635	372	24	7	607	18	576	2e-20	105
rs:WP_004897408	DNA topoisomerase I [Lactobacillus johnsonii].	25.33	525	312	20	7	505	12	482	2e-20	105
rs:WP_018084360	hypothetical protein [Desulfurispora thermophila].	24.38	603	359	24	5	579	4	537	2e-20	105
rs:WP_004894564	DNA topoisomerase I [Lactobacillus johnsonii].	25.71	525	310	20	7	505	12	482	2e-20	105
rs:WP_000179679	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	105
rs:WP_000179661	DNA topoisomerase I [Streptococcus mitis].	24.86	527	307	20	7	504	17	483	2e-20	105
rs:WP_014713336	DNA topoisomerase I [Streptococcus parasanguinis].	24.38	525	312	19	7	504	17	483	2e-20	105
tr:O53042_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.94	451	257	17	89	505	59	475	2e-20	105
rs:WP_023918171	DNA topoisomerase 1 [Streptococcus parasanguinis].	24.38	525	312	19	7	504	15	481	2e-20	105
rs:WP_000179680	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	105
rs:WP_000179642	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	105
rs:WP_013903584	DNA topoisomerase I [Streptococcus parasanguinis].	24.38	525	312	19	7	504	17	483	2e-20	105
rs:WP_017279968	DNA topoisomerase I [Helicobacter pylori].	27.39	449	262	16	89	505	59	475	2e-20	105
rs:WP_003632876	DNA topoisomerase I [Legionella longbeachae].	26.12	536	310	18	7	504	6	493	2e-20	105
rs:WP_000246895	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	105
rs:WP_028918474	DNA topoisomerase I [Pseudoxanthomonas sp. J35].	25.51	541	311	19	7	505	6	496	2e-20	106
rs:WP_000179678	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	105
rs:WP_031437885	DNA topoisomerase I [Methylobacter tundripaludum].	25.47	589	340	20	7	562	6	528	2e-20	105
rs:WP_000681448	DNA topoisomerase I [Helicobacter pylori].	27.39	449	262	16	89	505	59	475	2e-20	105
rs:WP_003014956	DNA topoisomerase I [Streptococcus parasanguinis].	24.38	525	312	19	7	504	17	483	2e-20	105
rs:WP_043872469	DNA topoisomerase I [Legionella massiliensis].	26.58	538	307	22	7	505	6	494	2e-20	105
rs:WP_031573190	DNA topoisomerase I [Streptococcus parasanguinis].	24.38	525	312	19	7	504	15	481	2e-20	105
rs:WP_043951872	DNA topoisomerase, partial [Enterococcus faecium].	32.30	226	136	8	5	223	33	248	2e-20	101
rs:WP_013788113	DNA topoisomerase I [Thermoanaerobacterium xylanolyticum].	24.78	577	326	21	7	553	6	504	2e-20	105
rs:WP_011153042	hypothetical protein [Nanoarchaeum equitans].	28.00	425	244	18	7	419	3	377	2e-20	103
rs:WP_034808918	DNA topoisomerase I [Exiguobacterium sp. AB2].	24.34	641	371	22	7	607	6	572	2e-20	105
rs:WP_019893231	hypothetical protein [Allobaculum stercoricanis].	26.44	522	310	20	7	505	6	476	2e-20	105
rs:WP_032443669	DNA topoisomerase III, partial [Klebsiella pneumoniae].	30.30	264	155	7	306	546	10	267	2e-20	103
rs:WP_000179650	DNA topoisomerase I [Streptococcus pneumoniae].	25.19	524	309	20	7	504	17	483	2e-20	105
rs:WP_046923200	DNA topoisomerase I [Lactobacillus ruminis].	25.38	528	309	21	7	505	26	497	2e-20	105
rs:WP_002883915	DNA topoisomerase I [Streptococcus salivarius].	24.14	526	312	18	7	504	34	500	2e-20	105
rs:WP_043752749	DNA topoisomerase I, partial [Thiorhodococcus sp. AK35].	24.36	546	310	19	7	505	4	493	2e-20	105
rs:WP_000179648	DNA topoisomerase I [Streptococcus pneumoniae].	25.19	524	309	20	7	504	17	483	2e-20	105
rs:WP_041171366	DNA topoisomerase I [Streptococcus pneumoniae].	25.05	527	306	20	7	504	17	483	2e-20	105
tr:B2IPL8_STRPS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.86	527	307	20	7	504	23	489	2e-20	105
rs:WP_000179643	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	105
rs:WP_042520547	DNA topoisomerase I [Lactobacillus brevis].	25.00	528	311	21	7	505	22	493	2e-20	105
rs:WP_017707944	hypothetical protein [Pseudomonas syringae].	26.54	437	260	15	99	504	66	472	2e-20	105
rs:WP_000179631	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	2e-20	105
rs:WP_042096603	DNA topoisomerase III, partial [Escherichia coli].	30.30	264	155	7	306	546	10	267	2e-20	103
rs:WP_002831689	DNA topoisomerase I [Pediococcus acidilactici].	25.52	525	312	22	7	505	9	480	2e-20	105
tr:X1DF39_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_C00312 {ECO:0000313|EMBL:GAH19441.1}; Flags: Fragment;	22.91	537	356	14	7	530	4	495	3e-20	104
rs:WP_025313569	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	17	89	505	59	475	3e-20	105
rs:WP_013247607	DNA topoisomerase I [Candidatus Nitrospira defluvii].	25.35	576	310	24	7	516	6	527	3e-20	105
rs:WP_032820832	topoisomerase I, partial [Oenococcus oeni].	30.00	300	188	11	279	563	6	298	3e-20	103
rs:WP_000179658	DNA topoisomerase I [Streptococcus mitis].	24.86	527	307	20	7	504	17	483	3e-20	105
rs:WP_019563323	DNA topoisomerase I [Thioalkalivibrio sp. ALMg2].	26.07	537	311	22	7	505	6	494	3e-20	105
rs:WP_025801906	DNA topoisomerase I [Campylobacter sp. CIT045].	24.83	435	289	13	89	505	59	473	3e-20	105
rs:WP_000179620	DNA topoisomerase I [Streptococcus pneumoniae].	25.19	524	309	20	7	504	17	483	3e-20	105
rs:WP_032825761	topoisomerase I, partial [Oenococcus oeni].	28.53	340	215	12	279	603	6	332	3e-20	103
rs:WP_020057405	DNA topoisomerase I [alpha proteobacterium SCGC AAA076-C03].	26.31	536	307	25	4	505	1	482	3e-20	105
rs:WP_000179659	DNA topoisomerase I [Streptococcus mitis].	24.86	527	307	20	7	504	17	483	3e-20	105
rs:WP_023940227	DNA topoisomerase I [Streptococcus pseudopneumoniae].	26.14	528	299	23	7	504	17	483	3e-20	105
rs:WP_024862330	DNA topoisomerase I [Pediococcus acidilactici].	25.47	530	306	22	7	505	9	480	3e-20	105
tr:E9FHA4_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.42	520	318	17	7	504	23	489	3e-20	105
rs:WP_023938619	DNA topoisomerase I [Streptococcus pseudopneumoniae].	25.19	524	309	20	7	504	17	483	3e-20	105
rs:WP_008036521	DNA topoisomerase I [Rhodobacterales bacterium HTCC2255].	26.31	536	307	25	4	505	1	482	3e-20	105
rs:WP_018949196	DNA topoisomerase I [Thioalkalivibrio sp. ALMg11].	26.07	537	311	22	7	505	6	494	3e-20	105
rs:WP_033123370	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	17	89	505	59	475	3e-20	105
rs:WP_000179646	DNA topoisomerase I [Streptococcus pneumoniae].	25.19	524	309	20	7	504	17	483	3e-20	105
rs:WP_025046431	DNA topoisomerase I [Sulfitobacter mediterraneus].	25.73	548	309	23	4	510	1	491	3e-20	105
rs:WP_024114980	DNA topoisomerase I [Helicobacter pylori].	27.39	449	262	16	89	505	59	475	3e-20	105
rs:WP_000962891	hypothetical protein, partial [Vibrio cholerae].	31.76	170	112	1	374	539	1	170	3e-20	101
rs:WP_042751276	DNA topoisomerase I [Streptococcus mitis].	24.86	527	307	20	7	504	17	483	3e-20	105
rs:WP_000445597	DNA topoisomerase I [Streptococcus pneumoniae].	25.00	524	304	20	10	504	2	465	3e-20	105
rs:WP_002358501	DNA topoisomerase, partial [Enterococcus faecium].	30.45	266	163	7	314	563	12	271	3e-20	102
rs:WP_000179618	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	3e-20	105
rs:WP_039665002	DNA topoisomerase I [Campylobacter volucris].	23.93	514	318	15	7	500	5	465	3e-20	105
tr:A0A077HMZ8_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.64	546	320	22	5	505	7	511	3e-20	105
rs:WP_042490506	DNA topoisomerase I [Sphingomonas parapaucimobilis].	26.86	525	304	23	7	505	4	474	3e-20	105
tr:D1YJE5_LACGS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.36	435	265	16	97	505	26	435	3e-20	105
rs:WP_033677361	DNA topoisomerase I [Streptococcus mitis].	24.86	527	307	20	7	504	17	483	3e-20	105
tr:G5H1L9_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.46	542	322	22	97	602	37	532	3e-20	105
rs:WP_014567529	DNA topoisomerase I [Lactobacillus johnsonii].	25.71	525	310	20	7	505	12	482	3e-20	105
rs:WP_010783371	DNA topoisomerase III, partial [Enterococcus faecalis].	27.20	353	242	8	201	544	9	355	3e-20	104
rs:WP_038613599	DNA topoisomerase I [Corynebacterium ureicelerivorans].	25.64	546	320	22	5	505	11	515	3e-20	105
rs:WP_024894350	DNA topoisomerase I [Acidithiobacillus thiooxidans].	23.79	597	341	21	7	563	6	528	3e-20	105
rs:WP_018364712	DNA topoisomerase I [Streptococcus caballi].	24.90	518	318	18	7	504	32	498	3e-20	105
rs:WP_046971205	DNA topoisomerase I [Dyella japonica].	26.34	543	308	21	7	505	6	500	3e-20	105
rs:WP_007522106	DNA topoisomerase I [Streptococcus tigurinus].	24.42	520	318	17	7	504	17	483	3e-20	105
tr:U4TQT7_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.49	612	348	25	7	586	1	536	3e-20	105
gpu:CP011770_2062	DNA topoisomerase I [Croceicoccus naphthovorans]	28.25	538	281	27	7	505	4	475	3e-20	105
rs:WP_017380848	DNA topoisomerase I [Paenisporosarcina sp. TG-14].	28.04	428	244	16	112	504	82	480	3e-20	105
rs:WP_000179647	DNA topoisomerase I, partial [Streptococcus pneumoniae].	25.19	524	309	20	7	504	17	483	3e-20	105
rs:WP_028893704	hypothetical protein [Syntrophorhabdus aromaticivorans].	26.21	538	310	20	7	510	6	490	3e-20	105
rs:WP_029639161	DNA topoisomerase I [alpha proteobacterium Mf 1.05b.01].	24.68	543	315	22	4	505	1	490	3e-20	105
rs:WP_045611818	DNA topoisomerase I [Streptococcus mitis].	24.86	527	307	20	7	504	17	483	3e-20	105
rs:WP_012824940	DNA topoisomerase I [Halothiobacillus neapolitanus].	26.69	547	307	24	3	505	2	498	3e-20	105
rs:WP_022184182	DNA topoisomerase type IA central domain protein [Eggerthella sp. CAG:209].	24.07	511	333	15	65	562	107	575	3e-20	105
rs:WP_022735463	DNA topoisomerase I [Candidatus Pelagibacter ubique].	24.58	541	316	23	4	505	1	488	3e-20	105
rs:WP_045763428	DNA topoisomerase I [Streptococcus mitis].	23.85	520	321	17	7	504	17	483	3e-20	105
rs:WP_000179630	DNA topoisomerase I [Streptococcus pneumoniae].	25.05	527	306	20	7	504	17	483	3e-20	105
rs:WP_011992733	DNA topoisomerase I [Campylobacter curvus].	25.53	517	321	17	7	505	5	475	3e-20	105
rs:WP_040429651	DNA topoisomerase I, partial [Acidithiobacillus thiooxidans].	23.79	597	341	21	7	563	6	528	3e-20	105
rs:WP_026804216	DNA topoisomerase I [Arcobacter sp. AF1581].	26.58	538	298	23	7	504	5	485	3e-20	105
rs:WP_011161948	DNA topoisomerase I [Lactobacillus johnsonii].	25.52	525	311	20	7	505	12	482	3e-20	105
rs:WP_045124713	MULTISPECIES: conjugal transfer protein TraB [Acinetobacter calcoaceticus/baumannii complex].	25.30	498	294	19	93	558	59	510	3e-20	105
rs:WP_026808340	MULTISPECIES: DNA topoisomerase I [Arcobacter].	26.58	538	298	23	7	504	5	485	3e-20	105
rs:WP_045829100	DNA topoisomerase I [Luteibacter yeojuensis].	25.51	490	300	18	109	568	79	533	3e-20	105
rs:WP_035421699	DNA topoisomerase I [Lactobacillus florum].	25.67	526	308	22	7	504	24	494	3e-20	105
rs:WP_000179674	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	3e-20	105
rs:WP_024421569	DNA topoisomerase I [Helicobacter pylori].	27.39	449	262	16	89	505	59	475	3e-20	105
rs:WP_000179652	DNA topoisomerase I [Streptococcus pneumoniae].	25.19	524	309	20	7	504	17	483	3e-20	105
rs:WP_018122573	hypothetical protein [Wohlfahrtiimonas chitiniclastica].	25.78	543	310	19	3	504	2	492	3e-20	105
rs:WP_032821696	topoisomerase I, partial [Oenococcus oeni].	28.13	327	201	11	200	508	1	311	3e-20	102
rs:WP_033685170	DNA topoisomerase I [Streptococcus mitis].	24.86	527	307	20	7	504	17	483	3e-20	105
rs:WP_000179649	DNA topoisomerase I [Streptococcus pneumoniae].	25.19	524	309	20	7	504	17	483	3e-20	105
rs:WP_039395112	DNA topoisomerase I, partial [Novosphingobium sp. MBES04].	27.53	523	304	21	7	505	4	475	3e-20	105
rs:WP_025015133	DNA topoisomerase I [Lactobacillus kitasatonis].	24.52	526	320	18	5	505	17	490	3e-20	105
rs:WP_024948064	DNA topoisomerase I [Helicobacter pylori].	27.39	449	262	16	89	505	59	475	3e-20	105
rs:WP_034017814	hypothetical protein [Pseudomonas aeruginosa].	25.97	489	295	18	43	505	26	473	3e-20	105
rs:WP_028273113	DNA topoisomerase I [Atopococcus tabaci].	24.72	534	322	18	1	505	1	483	3e-20	105
tr:C9LHI7_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEX71447.1};	28.77	285	175	9	262	531	41	312	3e-20	103
rs:WP_000179677	DNA topoisomerase I [Streptococcus sp. SK140].	24.23	520	319	17	7	504	17	483	3e-20	105
rs:WP_025439297	DNA topoisomerase I [Komagataeibacter xylinus].	25.77	555	307	25	7	510	5	505	4e-20	105
rs:WP_011096652	DNA topoisomerase I [Tropheryma whipplei].	24.95	537	323	18	7	504	5	500	4e-20	105
rs:WP_006904981	DNA topoisomerase I [Thermaerobacter subterraneus].	25.26	578	333	21	5	553	4	511	4e-20	105
rs:WP_000681495	DNA topoisomerase I [Helicobacter pylori].	27.39	449	262	16	89	505	59	475	4e-20	105
rs:WP_022280660	DNA topoisomerase [Lactobacillus ruminis CAG:367].	25.38	528	309	21	7	505	26	497	4e-20	105
rs:WP_044477088	DNA topoisomerase III, partial [Oceanobacillus massiliensis].	34.93	209	119	7	5	206	4	202	4e-20	99.8
tr:U2E4L1_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERI89122.1};	31.01	258	150	11	291	531	24	270	4e-20	103
rs:WP_039384579	DNA topoisomerase I [Pantoea sp. PSNIH1].	26.59	455	292	15	69	505	68	498	4e-20	105
rs:WP_039704144	DNA topoisomerase I [Helicobacter pylori].	27.90	448	260	17	89	505	59	474	4e-20	105
rs:WP_000179633	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	4e-20	105
rs:WP_000681493	DNA topoisomerase I [Helicobacter pylori].	27.39	449	262	16	89	505	59	475	4e-20	105
tr:F8XQU4_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	27.58	446	266	20	89	505	59	476	4e-20	103
rs:WP_011102734	DNA topoisomerase I [Tropheryma whipplei].	24.95	537	323	18	7	504	5	500	4e-20	105
rs:WP_025084927	DNA topoisomerase I [Lactobacillus paralimentarius].	24.62	528	317	18	7	505	9	484	4e-20	105
sp:TOP1_AQUAE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	26.47	612	328	28	7	589	4	522	4e-20	104
rs:WP_031572692	DNA topoisomerase I [Acidithiobacillus thiooxidans].	23.79	597	341	21	7	563	6	528	4e-20	105
rs:WP_033681703	DNA topoisomerase I [Streptococcus mitis].	25.19	524	303	20	10	504	2	465	4e-20	105
tr:A0A015PAY0_BACFG	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXY30277.1}; Flags: Fragment;	23.01	539	343	18	18	531	5	496	4e-20	104
rs:WP_000681496	DNA topoisomerase I [Helicobacter pylori].	27.17	449	263	16	89	505	59	475	4e-20	105
rs:WP_000681489	DNA topoisomerase I [Helicobacter pylori].	27.72	451	258	17	89	505	59	475	4e-20	105
rs:WP_027307457	DNA topoisomerase I [Caloramator sp. ALD01].	24.15	621	373	22	7	601	6	554	4e-20	104
rs:WP_006341833	DNA topoisomerase I [Parachlamydia acanthamoebae].	25.70	533	320	19	7	504	6	497	4e-20	105
rs:WP_010976540	DNA topoisomerase I [Streptococcus pneumoniae].	25.19	524	309	20	7	504	23	489	4e-20	105
rs:WP_003088291	DNA topoisomerase I [Streptococcus ratti].	25.05	527	307	19	7	504	24	491	4e-20	105
rs:WP_032991737	DNA topoisomerase III, partial [Cronobacter dublinensis].	32.42	182	111	4	374	548	4	180	4e-20	101
rs:WP_008840962	DNA topoisomerase I [Pediococcus lolii].	25.52	525	312	22	7	505	9	480	4e-20	104
rs:WP_025916648	DNA topoisomerase III, partial [Herminiimonas sp. CN].	29.77	309	186	13	260	550	23	318	4e-20	104
rs:WP_020902794	DNA topoisomerase I [Streptococcus mitis].	24.86	527	307	20	7	504	17	483	4e-20	104
rs:WP_039123365	DNA topoisomerase I [Lactobacillus ruminis].	26.00	527	301	22	10	505	2	470	4e-20	104
rs:WP_000179664	DNA topoisomerase I [Streptococcus mitis].	24.86	527	307	20	7	504	17	483	4e-20	104
rs:WP_021310272	DNA topoisomerase I [Helicobacter pylori].	27.39	449	262	16	89	505	59	475	4e-20	105
rs:WP_044791351	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	4e-20	104
rs:WP_028317283	DNA topoisomerase I [Desulfobulbus elongatus].	26.24	423	263	13	107	505	74	471	4e-20	104
rs:WP_006892984	DNA topoisomerase I [Methylobacter tundripaludum].	25.47	589	340	20	7	562	6	528	4e-20	105
rs:WP_022623213	topoisomerase I [Pantoea ananatis].	27.57	457	285	16	69	505	68	498	4e-20	105
rs:WP_043118135	DNA topoisomerase I [Solemya velum gill symbiont].	26.63	552	309	23	7	512	4	505	4e-20	105
rs:WP_016398196	DNA topoisomerase I [Streptococcus pneumoniae].	24.86	527	307	20	7	504	17	483	4e-20	104
rs:WP_035612931	DNA topoisomerase I [Hyphomonas johnsonii].	26.18	531	308	23	7	505	4	482	4e-20	105
rs:WP_000681475	DNA topoisomerase I [Helicobacter pylori].	27.39	449	262	16	89	505	59	475	4e-20	104
rs:WP_000681467	DNA topoisomerase I [Helicobacter pylori].	27.39	449	262	17	89	505	59	475	4e-20	104
rs:WP_023440369	DNA topoisomerase I [Pediococcus pentosaceus].	25.62	527	309	20	7	505	9	480	5e-20	104
rs:WP_010726672	hypothetical protein, partial [Enterococcus faecium].	24.48	429	267	15	124	534	7	396	5e-20	104
tr:T2SB35_HELPX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.27	451	260	16	89	505	59	475	5e-20	104
tr:F5W1Z7_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.12	430	276	12	97	504	31	436	5e-20	104
rs:WP_032825177	topoisomerase I, partial [Oenococcus oeni].	28.13	327	201	11	200	508	1	311	5e-20	101
rs:WP_033368960	DNA topoisomerase I [Selenomonas bovis].	24.84	628	366	28	5	594	39	598	5e-20	104
rs:WP_029658312	DNA topoisomerase I [Streptococcus pneumoniae].	25.53	521	305	20	10	504	2	465	5e-20	104
tr:T2J8Q9_CROWT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.29	445	278	15	104	519	77	500	5e-20	104
rs:WP_010619796	DNA topoisomerase I [Lactobacillus malefermentans].	25.76	528	305	22	7	504	18	488	5e-20	104
rs:WP_024111853	DNA topoisomerase I [Helicobacter pylori].	27.39	449	262	16	89	505	59	475	5e-20	104
rs:WP_000681451	DNA topoisomerase I [Helicobacter pylori].	27.39	449	262	16	89	505	59	475	5e-20	104
rs:WP_012570516	DNA topoisomerase I [Coxiella burnetii].	24.27	651	357	28	7	582	6	595	5e-20	104
rs:WP_011667572	DNA topoisomerase I [Lactobacillus brevis].	24.81	528	312	21	7	505	22	493	5e-20	104
rs:WP_004222575	DNA topoisomerase III [Bifidobacterium pseudocatenulatum].	26.38	326	201	10	7	322	4	300	5e-20	102
rs:WP_000445593	DNA topoisomerase I [Streptococcus pneumoniae].	25.00	524	304	20	10	504	2	465	5e-20	104
rs:WP_009161146	DNA topoisomerase, partial [Prevotella saccharolytica].	28.29	251	165	6	275	515	57	302	5e-20	101
gpu:LN847353_1153	DNA topoisomerase I [Streptococcus pneumoniae]	24.62	532	302	20	7	504	17	483	5e-20	104
rs:WP_029238789	DNA topoisomerase I, partial [Streptococcus sobrinus].	25.90	529	300	23	7	504	33	500	5e-20	104
rs:WP_005720234	DNA topoisomerase I [Lactobacillus crispatus].	24.09	635	372	24	7	607	18	576	5e-20	104
rs:WP_005769743	DNA topoisomerase I [Coxiella burnetii].	24.27	651	357	28	7	582	6	595	5e-20	104
rs:WP_013820830	DNA topoisomerase I [Methylomonas methanica].	26.20	542	314	18	3	505	2	496	5e-20	104
rs:WP_025229321	hypothetical protein [Fimbriimonas ginsengisoli].	24.70	660	348	29	7	590	6	592	5e-20	105
rs:WP_025024322	DNA topoisomerase I [Lactobacillus nodensis].	25.10	526	315	19	7	504	9	483	5e-20	104
rs:WP_024370092	DNA topoisomerase I [Exiguobacterium sp. 8-11-1].	24.49	637	375	22	7	607	6	572	5e-20	104
rs:WP_031881006	DNA topoisomerase III, partial [Staphylococcus aureus].	31.02	303	192	9	5	301	3	294	5e-20	101
rs:WP_040948035	DNA topoisomerase I [Coxiella burnetii].	24.27	651	357	28	7	582	6	595	5e-20	104
tr:T0RST2_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.43	572	339	19	7	544	73	579	5e-20	104
rs:WP_039669638	DNA topoisomerase I [Coxiella burnetii].	24.27	651	357	28	7	582	6	595	5e-20	104
rs:WP_005772159	DNA topoisomerase I [Coxiella burnetii].	24.27	651	357	28	7	582	6	595	5e-20	104
rs:WP_010958589	DNA topoisomerase I [Coxiella burnetii].	24.27	651	357	28	7	582	6	595	5e-20	104
rs:WP_025167044	DNA topoisomerase I [Pseudomonas taeanensis].	25.90	529	327	19	97	603	75	560	5e-20	104
rs:WP_000179636	DNA topoisomerase I [Streptococcus pneumoniae].	24.67	527	308	20	7	504	17	483	5e-20	104
tr:E7FNV6_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.38	528	309	21	7	505	26	497	6e-20	104
rs:WP_035426888	DNA topoisomerase [Atopobium sp. ICM42b].	22.11	511	348	15	65	563	109	581	6e-20	104
rs:WP_034419954	DNA topoisomerase I [Clostridiales bacterium DRI-13].	25.38	528	312	20	7	504	9	484	6e-20	104
rs:WP_042900774	DNA topoisomerase I [Streptococcus mitis].	24.86	527	307	20	7	504	17	483	6e-20	104
rs:WP_015473756	DNA topoisomerase 1 [Lactobacillus brevis].	24.81	528	312	21	7	505	22	493	6e-20	104
rs:WP_023946902	DNA topoisomerase I [Streptococcus mitis].	24.86	527	307	20	7	504	17	483	6e-20	104
tr:G5GLW4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.10	639	370	28	5	607	4	563	6e-20	104
rs:WP_024650174	DNA topoisomerase III, partial [Pseudomonas syringae].	26.27	335	229	10	4	333	1	322	6e-20	101
tr:L2H5I4_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.20	353	242	8	201	544	15	361	6e-20	103
rs:WP_034722352	hypothetical protein, partial [Bacteriovorax sp. DB6_IX].	23.43	572	339	19	7	544	76	582	6e-20	104
rs:YP_003446332	DNA topoisomerase I [Streptococcus mitis B6].	24.86	527	307	20	7	504	17	483	6e-20	104
rs:WP_027886918	MULTISPECIES: DNA topoisomerase I [Meiothermus].	23.91	644	356	25	1	579	1	575	6e-20	104
rs:WP_045642951	DNA topoisomerase I [Peptococcaceae bacterium BRH_c8a].	24.15	617	357	25	5	586	21	561	6e-20	104
rs:WP_022724748	DNA topoisomerase I [alpha proteobacterium SCGC AAA536-K22].	27.22	529	305	22	7	505	4	482	6e-20	104
rs:WP_003024471	DNA topoisomerase I [Streptococcus anginosus].	24.29	531	305	18	7	504	16	482	6e-20	104
rs:WP_033655835	DNA topoisomerase, partial [Enterococcus faecium].	27.20	353	242	8	201	544	16	362	6e-20	103
tr:R2SAC7_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.16	316	207	9	295	599	2	308	6e-20	102
rs:WP_000179675	DNA topoisomerase I [Streptococcus oralis].	24.23	520	319	17	7	504	17	483	6e-20	104
rs:WP_013979502	DNA topoisomerase [Eggerthella sp. YY7918].	23.94	543	352	18	65	585	107	610	6e-20	104
rs:WP_008609910	topoisomerase I [Alishewanella aestuarii].	25.23	539	314	19	7	505	6	495	6e-20	104
rs:WP_007307655	DNA topoisomerase I [Crocosphaera watsonii].	26.29	445	278	15	104	519	77	500	6e-20	104
rs:WP_038144779	DNA topoisomerase I [Thioclava sp. 13D2W-2].	26.45	533	305	24	4	505	1	477	6e-20	104
rs:WP_039099413	DNA topoisomerase I [Lactobacillus curvatus].	24.58	533	323	18	1	504	1	483	6e-20	104
rs:WP_013437787	MULTISPECIES: DNA topoisomerase I [Lactobacillus].	24.52	526	320	18	5	505	17	490	6e-20	104
rs:WP_011413890	DNA topoisomerase I [Erythrobacter litoralis].	27.49	542	296	25	7	510	4	486	6e-20	104
rs:WP_021304414	DNA topoisomerase I [Helicobacter pylori].	27.62	449	261	16	89	505	59	475	6e-20	104
rs:WP_031440482	MULTISPECIES: DNA topoisomerase I [Sphingomonas].	26.45	518	315	19	7	505	4	474	6e-20	104
rs:WP_036085525	DNA topoisomerase I [Listeria booriae].	27.80	428	251	16	109	504	79	480	6e-20	104
rs:WP_005407451	DNA topoisomerase I [Acinetobacter radioresistens].	25.09	538	317	21	80	581	46	533	6e-20	104
rs:WP_000179641	DNA topoisomerase I [Streptococcus pneumoniae].	24.67	527	308	20	7	504	17	483	6e-20	104
rs:WP_006905958	DNA topoisomerase III [Shuttleworthia satelles].	25.53	376	215	11	284	598	356	727	6e-20	104
rs:WP_006905958	DNA topoisomerase III [Shuttleworthia satelles].	25.42	236	167	6	5	236	4	234	7e-13	82.0
rs:WP_007344964	DNA topoisomerase I [Halorubrum terrestre].	22.65	543	343	18	7	498	8	524	6e-20	104
rs:WP_038074878	DNA topoisomerase I [Thioclava pacifica].	26.07	537	302	24	4	505	1	477	7e-20	104
rs:WP_019491917	DNA topoisomerase I [Calothrix sp. PCC 7103].	25.72	451	285	14	84	504	59	489	7e-20	104
rs:WP_021307189	DNA topoisomerase I [Helicobacter pylori].	27.46	448	263	15	89	505	59	475	7e-20	104
rs:WP_018167332	DNA topoisomerase I [Streptococcus minor].	23.72	527	314	19	7	504	22	489	7e-20	104
rs:WP_034102734	DNA topoisomerase I [Desulfotomaculum sp. BICA1-6].	24.76	618	352	26	5	586	4	544	7e-20	104
rs:WP_045597118	DNA topoisomerase I [Streptococcus mitis].	24.67	527	308	20	7	504	17	483	7e-20	104
tr:K1Z1A0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.52	525	316	19	7	505	5	480	7e-20	104
rs:WP_044010110	DNA topoisomerase I [Lactobacillus sp. WDC04].	26.29	525	308	23	7	505	27	498	7e-20	104
rs:WP_000445598	DNA topoisomerase I [Streptococcus pneumoniae].	25.34	521	306	20	10	504	2	465	7e-20	104
rs:WP_035028195	DNA topoisomerase I [Carnobacterium mobile].	26.00	523	314	18	7	504	7	481	7e-20	104
rs:WP_021510115	topoisomerase I [Pantoea dispersa].	27.25	455	289	16	69	505	68	498	7e-20	104
rs:WP_009182186	DNA topoisomerase I [Desulfovibrio sp. FW1012B].	26.30	422	263	16	107	505	75	471	7e-20	103
rs:WP_008844703	DNA topoisomerase I [Aliiglaciecola lipolytica].	25.23	539	324	19	7	505	6	505	7e-20	104
rs:WP_007746465	DNA topoisomerase I [Oenococcus kitaharae].	27.48	433	245	16	107	504	83	481	7e-20	103
rs:WP_012711318	DNA topoisomerase I [Sulfolobus islandicus].	23.33	540	339	18	42	564	53	534	7e-20	103
rs:WP_044993277	DNA topoisomerase I [Lachnospiraceae bacterium JC7].	23.61	610	358	23	7	586	6	537	7e-20	103
rs:WP_019791054	DNA topoisomerase I, partial [Streptococcus sobrinus].	25.80	531	298	23	7	504	33	500	7e-20	103
rs:WP_013320619	DNA topoisomerase I [Cyanothece sp. PCC 7822].	26.93	453	269	17	88	505	63	488	7e-20	104
rs:WP_004818409	DNA topoisomerase, partial [Anaerococcus hydrogenalis].	27.24	279	187	6	266	539	35	302	7e-20	101
rs:WP_039718007	DNA topoisomerase I [Scytonema millei].	25.32	541	311	22	4	505	1	487	7e-20	104
rs:WP_010229101	DNA topoisomerase I [Chlamydia muridarum].	26.09	552	327	21	46	563	30	534	7e-20	104
rs:WP_043106819	DNA topoisomerase I [endosymbiont of unidentified scaly snail isolate Monju].	25.56	536	314	20	7	505	4	491	7e-20	104
rs:WP_034434629	DNA topoisomerase I [Clostridiales bacterium S5-A14a].	27.43	536	302	25	7	510	14	494	7e-20	103
rs:WP_031396094	DNA topoisomerase I, partial [Sphingomonas sp. STIS6.2].	26.64	518	314	19	7	505	4	474	7e-20	103
rs:WP_044346183	DNA topoisomerase I [Desulfarculus sp. SPR].	26.36	535	304	21	7	505	6	486	7e-20	104
tr:A7BSD2_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.17	554	300	22	7	505	6	505	7e-20	104
rs:WP_031434896	DNA topoisomerase I [Methylomarinum vadi].	24.21	537	322	16	7	505	6	495	7e-20	104
rs:WP_039957093	DNA topoisomerase I [Selenomonas infelix].	24.10	639	370	28	5	607	20	579	7e-20	104
rs:WP_038104331	DNA topoisomerase I [Tropheryma whipplei].	24.95	537	323	18	7	504	5	500	7e-20	104
rs:WP_034077591	DNA topoisomerase I [Pseudomonas aeruginosa].	27.00	437	273	16	91	505	59	471	7e-20	103
rs:WP_045923410	DNA topoisomerase I [Lactobacillus mellis].	25.81	527	311	22	7	504	24	499	7e-20	103
rs:WP_021155407	MULTISPECIES: DNA topoisomerase I [Proteobacteria].	27.00	437	273	16	91	505	59	471	7e-20	103
tr:T0NBF8_9CLOT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EQB87485.1};	27.63	304	195	11	7	293	6	301	8e-20	100
rs:WP_007892424	topoisomerase I [Pantoea sp. GM01].	27.25	455	289	16	69	505	68	498	8e-20	104
rs:WP_001722109	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	25.60	539	315	20	7	505	6	498	8e-20	103
rs:WP_020997791	DNA topoisomerase I [Streptococcus constellatus].	24.29	531	305	18	7	504	16	482	8e-20	103
tr:A0A0B8PEW1_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	34.74	190	110	4	278	459	20	203	8e-20	99.8
rs:WP_034821487	DNA topoisomerase I [Enterobacter cancerogenus].	26.37	455	293	15	69	505	68	498	8e-20	104
rs:WP_043061269	DNA topoisomerase I [Sphingomonas taxi].	27.60	529	295	24	7	505	4	474	8e-20	104
rs:WP_029570068	DNA topoisomerase I [Pantoea ananatis].	27.35	457	286	16	69	505	68	498	8e-20	104
rs:WP_009201701	DNA topoisomerase I [Anaerobaculum hydrogeniformans].	26.05	526	304	21	7	504	10	478	8e-20	103
rs:WP_011181594	DNA topoisomerase I, partial [Bacillus thuringiensis].	29.14	302	192	6	112	408	51	335	8e-20	100
rs:WP_042506202	DNA topoisomerase I [Tropheryma whipplei].	24.95	537	323	18	7	504	5	500	8e-20	104
rs:WP_001734569	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	25.60	539	315	20	7	505	6	498	8e-20	103
tr:C7VPQ1_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.91	353	243	8	201	544	12	358	8e-20	103
rs:WP_041784112	DNA topoisomerase I, partial [Streptococcus anginosus].	24.39	533	302	19	7	504	16	482	8e-20	103
tr:T1ZVG1_STRAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.39	533	302	19	7	504	16	482	8e-20	103
rs:WP_018375537	DNA topoisomerase I [Streptococcus orisratti].	25.05	527	307	19	7	504	28	495	8e-20	103
rs:WP_010269604	DNA topoisomerase I [Paenibacillus senegalensis].	25.38	524	317	21	7	504	6	481	8e-20	103
rs:WP_021305666	DNA topoisomerase I [Helicobacter pylori].	27.39	449	262	16	89	505	59	475	8e-20	103
rs:WP_029335400	DNA topoisomerase I [Exiguobacterium aurantiacum].	24.64	629	368	22	7	599	6	564	8e-20	103
rs:WP_007312723	DNA topoisomerase I, partial [Crocosphaera watsonii].	26.62	447	274	16	104	519	77	500	9e-20	103
rs:WP_000445595	DNA topoisomerase I [Streptococcus pneumoniae].	25.00	524	304	20	10	504	2	465	9e-20	103
rs:WP_033623889	DNA topoisomerase, partial [Enterococcus faecalis].	26.91	353	243	8	201	544	1	347	9e-20	103
rs:WP_013252301	DNA topoisomerase [Olsenella uli].	23.12	545	351	19	65	588	109	606	9e-20	104
rs:WP_020901448	DNA topoisomerase I [Streptococcus mitis].	24.67	527	308	20	7	504	17	483	9e-20	103
rs:WP_021273797	DNA topoisomerase I [Bacteriovorax sp. Seq25_V].	24.12	622	358	23	7	585	72	622	9e-20	103
rs:WP_001725981	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	25.60	539	315	20	7	505	6	498	9e-20	103
rs:WP_005016677	MULTISPECIES: topoisomerase I [Acinetobacter].	25.70	537	317	19	7	505	26	518	9e-20	104
rs:WP_039334683	DNA topoisomerase I [Pantoea rodasii].	26.48	457	290	16	69	505	68	498	9e-20	104
rs:WP_000445594	DNA topoisomerase I [Streptococcus pneumoniae].	25.00	524	304	20	10	504	2	465	9e-20	103
rs:WP_018146992	DNA topoisomerase I [Henriciella marina].	26.43	541	299	25	4	505	1	481	9e-20	103
rs:WP_034428678	DNA topoisomerase I [Acinetobacter radioresistens].	25.70	537	317	19	7	505	26	518	9e-20	104
rs:WP_036575662	DNA topoisomerase [Olsenella uli].	23.12	545	351	19	65	588	109	606	9e-20	103
rs:WP_000179662	DNA topoisomerase I [Streptococcus sp. M334].	24.67	527	308	20	7	504	17	483	9e-20	103
rs:WP_031268127	DNA topoisomerase I, partial [Corynebacterium pseudodiphtheriticum].	25.40	567	323	25	1	510	1	524	9e-20	104
rs:WP_018287834	DNA topoisomerase I [zeta proteobacterium SCGC AB-133-G06].	25.55	544	310	21	1	505	1	488	9e-20	103
tr:J9GIY8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJX07582.1};	27.21	294	178	8	43	327	2	268	9e-20	100
rs:WP_047263090	DNA topoisomerase I [Corynebacterium mustelae].	26.67	480	277	20	80	505	67	525	9e-20	104
rs:WP_003007403	DNA topoisomerase I [Streptococcus parasanguinis].	24.23	520	319	19	7	504	15	481	9e-20	103
tr:E7SBC1_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.76	529	305	21	7	504	27	493	9e-20	103
rs:WP_000445596	DNA topoisomerase I [Streptococcus pneumoniae].	25.00	524	304	20	10	504	2	465	9e-20	103
rs:WP_020858636	DNA topoisomerase I [SAR86 cluster bacterium SAR86B].	24.68	551	325	20	7	512	6	511	9e-20	103
rs:WP_014215391	DNA topoisomerase I [Pediococcus claussenii].	25.43	527	310	23	7	505	9	480	9e-20	103
rs:WP_022362848	DNA topoisomerase type IA central domain protein [Eggerthella sp. CAG:298].	24.20	533	344	18	66	584	108	594	1e-19	103
rs:WP_026861812	DNA topoisomerase I [Idiomarina sediminum].	22.94	523	356	14	7	505	6	505	1e-19	103
rs:WP_011256239	DNA topoisomerase I [Wolbachia endosymbiont of Brugia malayi].	25.47	534	311	21	7	504	4	486	1e-19	103
rs:WP_010962038	DNA topoisomerase I [Methylococcus capsulatus].	24.96	589	342	20	7	562	6	527	1e-19	103
rs:WP_033688907	DNA topoisomerase I [Streptococcus mitis].	25.00	524	304	20	10	504	2	465	1e-19	103
rs:WP_025068471	hypothetical protein, partial [Prevotella denticola].	26.51	347	216	11	5	339	3	322	1e-19	100
rs:WP_034038052	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	34.62	156	94	4	8	163	5	152	1e-19	97.4
rs:WP_019399203	DNA topoisomerase I [Pseudoxanthomonas sp. GW2].	26.02	538	312	19	7	505	6	496	1e-19	103
rs:WP_033627502	DNA topoisomerase, partial [Enterococcus faecium].	31.32	265	160	9	315	563	22	280	1e-19	102
rs:WP_036213490	DNA topoisomerase I [Lysobacter arseniciresistens].	24.39	537	322	19	7	505	6	496	1e-19	103
rs:WP_003693908	DNA topoisomerase I [Lactobacillus ruminis].	25.52	525	306	21	10	505	2	470	1e-19	103
rs:WP_038805367	DNA topoisomerase I [Streptococcus dentisani].	24.23	520	319	17	7	504	17	483	1e-19	103
rs:WP_027160116	DNA topoisomerase I [Methylobacter luteus].	25.47	589	340	20	7	562	6	528	1e-19	103
rs:WP_028914417	DNA topoisomerase I [Pseudoxanthomonas sp. J31].	26.02	538	312	19	7	505	6	496	1e-19	103
rs:WP_010406126	DNA topoisomerase I [Sphingomonas echinoides].	26.82	522	308	22	7	505	4	474	1e-19	103
rs:WP_045807821	DNA topoisomerase I [Lactobacillus spicheri].	24.76	521	321	20	7	505	22	493	1e-19	103
rs:WP_022028557	DNA topoisomerase [Clostridium sp. CAG:1219].	25.24	523	307	22	7	504	6	469	1e-19	103
rs:WP_005023286	MULTISPECIES: topoisomerase I [Acinetobacter].	25.70	537	317	19	7	505	26	518	1e-19	103
tr:K2EI12_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.91	548	305	20	4	506	1	492	1e-19	103
rs:WP_036101696	DNA topoisomerase I [Listeria riparia].	27.80	428	251	16	109	504	79	480	1e-19	103
rs:WP_021890495	DNA topoisomerase [Succinatimonas sp. CAG:777].	26.58	587	327	27	7	558	6	523	1e-19	103
rs:WP_041027941	DNA topoisomerase I, partial [Salmonella enterica].	25.60	539	315	20	7	505	6	498	1e-19	103
rs:WP_046922440	DNA topoisomerase I [Lactobacillus ruminis].	25.10	522	318	20	7	505	26	497	1e-19	103
rs:WP_009606631	DNA topoisomerase I [Turicibacter sp. HGF1].	24.67	612	368	23	7	595	6	547	1e-19	103
rs:WP_019790039	DNA topoisomerase I [Streptococcus sobrinus].	24.19	525	314	18	7	504	33	500	1e-19	103
rs:WP_027493257	DNA topoisomerase I [Rhodanobacter sp. OR444].	26.25	541	311	21	7	505	6	500	1e-19	103
rs:WP_022685102	DNA topoisomerase I [Sphingomonas phyllosphaerae].	27.15	523	305	25	7	505	4	474	1e-19	103
rs:WP_012211826	DNA topoisomerase I [Lactobacillus helveticus].	24.81	524	317	17	7	505	19	490	1e-19	103
rs:WP_022740226	DNA topoisomerase [Adlercreutzia equolifaciens].	23.23	564	374	17	65	607	107	632	1e-19	103
rs:WP_009440258	DNA topoisomerase I [Selenomonas sp. oral taxon 138].	24.48	629	364	28	7	599	51	604	1e-19	103
rs:WP_003069065	DNA topoisomerase I [Streptococcus intermedius].	24.11	531	306	18	7	504	1	467	1e-19	103
rs:WP_046143534	DNA topoisomerase I [Devosia soli].	26.65	544	297	25	4	505	1	484	1e-19	103
tr:A0A060QAM0_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.67	561	312	25	1	510	1	507	1e-19	103
tr:R8ULT3_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.74	231	142	6	119	347	1	215	1e-19	99.4
rs:WP_028484168	DNA topoisomerase I [Thioalkalivibrio sp. ALE17].	25.91	548	309	24	7	505	6	505	1e-19	103
rs:WP_017942609	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	26.07	537	311	22	7	505	6	494	1e-19	103
rs:WP_011543972	DNA topoisomerase I [Lactobacillus delbrueckii].	25.72	521	314	18	7	504	39	509	1e-19	103
rs:WP_000681457	DNA topoisomerase I [Helicobacter pylori].	27.15	453	258	16	89	505	59	475	1e-19	103
rs:WP_038622494	DNA topoisomerase I [Dyella jiangningensis].	25.93	594	338	24	7	563	6	534	1e-19	103
tr:N1W1T2_9LEPT	SubName: Full=Putative DNA topoisomerase I {ECO:0000313|EMBL:EMY63225.1};	25.00	460	283	17	81	504	2	435	1e-19	103
rs:WP_029669905	DNA topoisomerase I [Streptococcus pneumoniae].	25.34	521	306	20	10	504	2	465	1e-19	103
rs:WP_000445599	DNA topoisomerase I [Streptococcus pneumoniae].	25.34	521	306	20	10	504	2	465	1e-19	103
rs:WP_004276466	DNA topoisomerase I [Campylobacter upsaliensis].	24.05	528	315	18	7	505	6	476	1e-19	103
rs:WP_008106525	topoisomerase I [Pantoea sp. YR343].	27.03	455	290	16	69	505	68	498	1e-19	103
rs:WP_019786482	DNA topoisomerase I, partial [Streptococcus sobrinus].	24.76	529	306	20	7	504	33	500	1e-19	103
rs:WP_003615350	DNA topoisomerase I [Lactobacillus delbrueckii].	25.72	521	314	18	7	504	36	506	1e-19	103
tr:A0A009N8A3_ACIBA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.70	537	317	19	7	505	1	493	1e-19	103
rs:WP_000179660	DNA topoisomerase I [Streptococcus mitis].	24.48	527	309	20	7	504	17	483	1e-19	103
tr:E9FJZ9_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.67	527	308	20	7	504	23	489	1e-19	103
rs:WP_009596063	DNA topoisomerase I [Xanthomonas translucens].	23.99	592	348	18	7	563	6	530	1e-19	103
rs:WP_024535012	DNA topoisomerase I [Sporosarcina sp. EUR3 2.2.2].	27.70	426	248	15	112	504	82	480	1e-19	103
rs:WP_040803059	DNA topoisomerase I [Streptococcus australis].	24.76	529	305	21	7	504	17	483	1e-19	103
tr:K9D1Y5_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.01	432	250	20	107	505	47	450	1e-19	103
rs:WP_003480796	DNA topoisomerase I [Xanthomonas translucens].	23.99	592	348	18	7	563	6	530	1e-19	103
rs:WP_038464132	DNA topoisomerase I [Candidatus Paracaedibacter acanthamoebae].	25.64	546	305	25	5	505	3	492	1e-19	103
tr:A0A0D6ZGG3_LACDE	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KIY24607.1};	25.72	521	314	18	7	504	39	509	1e-19	103
rs:WP_021002711	DNA topoisomerase I [Streptococcus intermedius].	24.95	533	299	19	7	504	16	482	1e-19	103
rs:WP_010019870	DNA topoisomerase I [Lactobacillus farciminis].	24.67	527	316	19	7	504	10	484	1e-19	103
rs:WP_009765522	DNA topoisomerase I [Sporosarcina newyorkensis].	27.06	425	262	15	107	504	77	480	1e-19	103
rs:WP_007039086	DNA topoisomerase I [Thiorhodococcus drewsii].	24.58	537	320	19	7	505	4	493	1e-19	103
rs:WP_003076379	DNA topoisomerase I [Streptococcus intermedius].	24.58	533	301	19	7	504	16	482	1e-19	103
rs:WP_027017461	DNA topoisomerase I [Corynebacterium pseudodiphtheriticum].	25.40	567	323	25	1	510	1	524	1e-19	103
rs:WP_042753922	DNA topoisomerase I [Streptococcus anginosus].	24.29	531	305	18	7	504	16	482	1e-19	103
rs:WP_035162822	DNA topoisomerase I [Caloranaerobacter azorensis].	25.41	492	310	16	93	564	63	517	1e-19	103
rs:WP_014770598	DNA topoisomerase I [Sulfurospirillum barnesii].	23.89	519	327	16	7	505	9	479	1e-19	103
rs:WP_023905388	DNA topoisomerase I [Xanthomonas hortorum].	24.32	592	346	20	7	563	6	530	1e-19	103
rs:WP_023018857	MULTISPECIES: DNA topoisomerase I [Corynebacterium].	25.40	567	323	25	1	510	1	524	1e-19	103
rs:WP_028989890	DNA topoisomerase I [Thermithiobacillus tepidarius].	25.19	536	316	18	7	505	6	493	1e-19	103
rs:WP_013025933	topoisomerase I [Pantoea ananatis].	27.35	457	286	16	69	505	68	498	1e-19	103
rs:WP_003470405	DNA topoisomerase I [Xanthomonas translucens].	23.99	592	348	18	7	563	6	530	1e-19	103
rs:WP_008366091	DNA topoisomerase I [Halorubrum litoreum].	22.65	543	343	18	7	498	8	524	1e-19	103
rs:WP_004598104	DNA topoisomerase I [Halorubrum distributum].	22.65	543	343	18	7	498	8	524	1e-19	103
rs:WP_044650215	DNA topoisomerase III, partial [Klebsiella variicola].	26.77	310	201	8	8	304	5	301	1e-19	99.8
rs:WP_047022332	DNA topoisomerase I [Arcobacter butzleri].	24.50	645	360	25	7	605	5	568	1e-19	103
gp:AP010969_875	DNA topoisomerase I [Streptococcus intermedius JTH08]	24.58	533	301	19	7	504	19	485	1e-19	103
rs:WP_018285616	hypothetical protein [zeta proteobacterium SCGC AB-133-C04].	25.11	442	279	13	97	505	66	488	1e-19	103
rs:WP_009568636	DNA topoisomerase I [Streptococcus intermedius].	24.95	533	299	19	7	504	16	482	1e-19	103
rs:WP_008459965	DNA topoisomerase I [Lactobacillus equicursoris].	24.44	626	365	24	7	603	38	584	1e-19	103
rs:WP_031514382	DNA topoisomerase I, partial [Desulfotomaculum alkaliphilum].	23.82	634	378	24	1	598	1	565	1e-19	103
rs:WP_018993132	DNA topoisomerase I [Thioalkalivibrio sp. ARh4].	25.54	556	307	23	7	505	6	511	1e-19	103
tr:A0A010EZ36_ACIBA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.70	537	317	19	7	505	1	493	1e-19	103
rs:WP_004270304	DNA topoisomerase I [Lactobacillus curvatus].	24.58	533	323	18	1	504	1	483	1e-19	103
rs:WP_021250287	DNA topoisomerase I [Thauera terpenica].	25.26	487	297	16	93	555	60	503	1e-19	103
tr:U2GQ65_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.40	567	323	25	1	510	1	524	1e-19	103
rs:WP_046995026	DNA topoisomerase I [Arcobacter butzleri].	24.50	645	360	25	7	605	5	568	1e-19	103
rs:WP_046998345	DNA topoisomerase I [Arcobacter butzleri].	24.50	645	360	25	7	605	5	568	1e-19	103
rs:WP_017296559	hypothetical protein [Nodosilinea nodulosa].	25.34	442	279	16	91	505	65	482	1e-19	103
tr:I0IL87_LEPFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.73	550	310	21	2	505	42	533	1e-19	103
tr:D4RGS5_ENTFC	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EFF26847.1}; Flags: Fragment;	30.13	229	142	6	5	225	3	221	1e-19	98.6
rs:WP_023023206	DNA topoisomerase I [Streptococcus sp. I-P16].	24.76	529	305	21	7	504	17	483	1e-19	103
rs:WP_020998619	DNA topoisomerase I [Streptococcus intermedius].	24.67	531	303	18	7	504	16	482	2e-19	103
tr:W1TZD8_STRAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.29	531	305	18	7	504	19	485	2e-19	103
tr:X5MHV7_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.94	516	288	24	44	510	1	476	2e-19	103
rs:WP_027071533	DNA topoisomerase I [Luteimonas sp. J29].	25.34	596	335	24	7	563	6	530	2e-19	103
rs:WP_006915959	DNA topoisomerase I [Lactobacillus coleohominis].	25.66	534	298	23	7	504	28	498	2e-19	103
rs:WP_009557733	DNA topoisomerase I [Lactobacillus equicursoris].	24.44	626	365	24	7	603	38	584	2e-19	103
rs:WP_034527452	DNA topoisomerase I [Lactobacillus oryzae].	25.72	521	314	21	7	504	17	487	2e-19	103
rs:WP_010943185	DNA topoisomerase I [Geobacter sulfurreducens].	25.89	533	313	19	7	505	6	490	2e-19	103
rs:WP_043561693	DNA topoisomerase I [Saccharibacter sp. AM169].	25.77	555	307	25	7	510	5	505	2e-19	103
rs:WP_034682714	DNA topoisomerase I [Acinetobacter baumannii].	25.70	537	317	19	7	505	26	518	2e-19	103
rs:WP_019304179	DNA topoisomerase I [Xanthomonas oryzae].	23.86	591	350	20	7	563	6	530	2e-19	103
rs:WP_024746280	DNA topoisomerase I [Lactobacillus namurensis].	24.57	521	322	20	7	505	22	493	2e-19	103
rs:WP_036692472	DNA topoisomerase I [Paenibacillus sp. FSL R7-269].	25.14	525	317	20	7	504	6	481	2e-19	103
rs:WP_013037299	DNA topoisomerase [Methanohalophilus mahii].	26.42	424	263	14	97	498	92	488	2e-19	103
rs:WP_016657559	DNA topoisomerase I [Acinetobacter rudis].	24.63	536	323	17	7	505	25	516	2e-19	103
rs:WP_000681466	DNA topoisomerase I [Helicobacter pylori].	27.27	451	260	17	89	505	59	475	2e-19	103
rs:WP_023169027	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	25.46	538	315	20	7	504	6	497	2e-19	102
tr:G4WVT3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.32	555	331	19	5	550	4	478	2e-19	103
rs:WP_006783782	DNA topoisomerase I [Turicibacter sanguinis].	24.67	612	368	23	7	595	6	547	2e-19	102
rs:WP_028263348	DNA topoisomerase [Atopobium fossor].	23.33	540	347	18	65	586	109	599	2e-19	103
rs:WP_034047566	DNA topoisomerase I [Pseudomonas aeruginosa].	26.77	437	274	16	91	505	59	471	2e-19	102
rs:WP_039006187	DNA topoisomerase I [Xanthomonas translucens].	23.99	592	348	18	7	563	6	530	2e-19	103
rs:WP_020504206	DNA topoisomerase I [Lamprocystis purpurea].	23.48	541	327	19	4	505	1	493	2e-19	103
rs:WP_040467782	DNA topoisomerase I [Lactobacillus gastricus].	26.24	526	305	24	7	504	35	505	2e-19	103
rs:WP_037584519	DNA topoisomerase I [Streptococcus intermedius].	24.58	533	301	19	7	504	17	483	2e-19	102
rs:WP_026485929	DNA topoisomerase I [Caldanaerobius polysaccharolyticus].	25.82	577	325	23	5	553	4	505	2e-19	102
rs:WP_019463844	DNA topoisomerase I [Dyella japonica].	25.14	541	317	20	7	505	6	500	2e-19	103
rs:WP_015202460	DNA topoisomerase I [Crinalium epipsammum].	24.40	545	340	18	91	603	65	569	2e-19	103
rs:WP_038110921	DNA topoisomerase I [Tropheryma whipplei].	24.95	537	323	18	7	504	5	500	2e-19	103
tr:U2KVD6_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.76	281	182	6	275	539	50	325	2e-19	102
rs:WP_006458716	DNA topoisomerase I [Synechococcus sp. PCC 7335].	26.09	460	281	16	93	517	68	503	2e-19	102
rs:WP_011678373	DNA topoisomerase I [Lactobacillus delbrueckii].	25.72	521	314	18	7	504	37	507	2e-19	103
rs:WP_021092863	DNA topoisomerase I [Campylobacter concisus].	27.83	442	269	16	89	505	59	475	2e-19	102
rs:WP_014469493	DNA topoisomerase I [Arcobacter butzleri].	24.50	645	360	25	7	605	5	568	2e-19	103
rs:WP_003618692	DNA topoisomerase I [Lactobacillus delbrueckii].	25.72	521	314	18	7	504	39	509	2e-19	103
rs:WP_029764261	DNA topoisomerase I [Gemmatimonadetes bacterium JGI 0000112-M07].	26.29	525	313	20	7	505	6	482	2e-19	102
rs:WP_019300052	DNA topoisomerase I [Xanthomonas oryzae].	23.86	591	350	20	7	563	6	530	2e-19	103
rs:WP_000513585	topoisomerase I [Salmonella enterica].	26.07	537	315	21	7	505	6	498	2e-19	103
tr:H4GHS5_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.05	526	306	23	7	504	25	495	2e-19	102
rs:WP_018371247	DNA topoisomerase I [Streptococcus massiliensis].	24.14	526	312	18	7	504	16	482	2e-19	102
rs:WP_017400709	topoisomerase I [Acinetobacter radioresistens].	25.70	537	317	19	7	505	26	518	2e-19	103
rs:WP_022416141	DNA topoisomerase [Dorea longicatena CAG:42].	25.69	401	235	13	213	554	7	403	2e-19	102
rs:WP_006269520	DNA topoisomerase I [Streptococcus constellatus].	24.11	531	306	18	7	504	16	482	2e-19	102
rs:WP_034550064	DNA topoisomerase I [Carnobacterium funditum].	24.86	523	320	17	7	504	7	481	2e-19	102
rs:WP_003698300	DNA topoisomerase I [Lactobacillus ruminis].	25.52	525	306	21	10	505	2	470	2e-19	102
rs:WP_047340222	DNA topoisomerase I [Xanthomonas oryzae].	23.86	591	350	20	7	563	6	530	2e-19	103
rs:WP_046438496	DNA topoisomerase I [Corynebacterium kutscheri].	26.44	469	277	17	86	505	75	524	2e-19	103
rs:WP_042824672	DNA topoisomerase III, partial [Xanthomonas axonopodis].	32.34	167	101	3	383	539	6	170	2e-19	98.2
rs:WP_042507044	DNA topoisomerase I [Tropheryma whipplei].	24.95	537	323	18	7	504	5	500	2e-19	103
rs:WP_018543479	MULTISPECIES: DNA topoisomerase I [Streptococcus anginosus group].	24.11	531	306	18	7	504	16	482	2e-19	102
rs:WP_020848635	DNA topoisomerase I [Arcobacter butzleri].	24.50	645	360	25	7	605	5	568	2e-19	103
rs:WP_046992000	DNA topoisomerase I [Arcobacter butzleri].	24.50	645	360	25	7	605	5	568	2e-19	102
rs:WP_035444428	DNA topoisomerase I [Asaia platycodi].	24.68	551	316	26	7	510	5	503	2e-19	103
rs:WP_019773343	DNA topoisomerase I, partial [Streptococcus sobrinus].	24.86	527	308	20	7	504	31	498	2e-19	102
rs:WP_024113581	DNA topoisomerase I [Helicobacter pylori].	27.17	449	263	16	89	505	59	475	2e-19	102
rs:WP_014073449	DNA topoisomerase I [Lactobacillus ruminis].	25.52	525	306	21	10	505	2	470	2e-19	102
rs:WP_041774651	DNA topoisomerase [Leptospirillum ferrooxidans].	24.73	550	310	21	2	505	8	499	2e-19	103
rs:WP_024711277	DNA topoisomerase I [Xanthomonas oryzae].	23.86	591	350	20	7	563	6	530	2e-19	103
tr:J7SJ75_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.32	629	365	28	7	599	37	590	2e-19	102
rs:WP_044960776	DNA topoisomerase III [Shuttleworthia sp. MSX8B].	25.99	377	213	12	284	598	356	728	2e-19	102
rs:WP_044960776	DNA topoisomerase III [Shuttleworthia sp. MSX8B].	25.63	238	164	7	5	236	4	234	1e-11	78.6
rs:WP_046996530	DNA topoisomerase I [Arcobacter butzleri].	24.50	645	360	25	7	605	5	568	2e-19	102
rs:WP_003030274	DNA topoisomerase I [Streptococcus anginosus].	24.11	531	306	18	7	504	16	482	2e-19	102
tr:A0A0B8REZ8_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.30	540	311	23	1	505	1	488	2e-19	103
rs:WP_022176407	DNA topoisomerase [Firmicutes bacterium CAG:552].	24.34	534	334	18	97	601	65	557	2e-19	102
rs:WP_032111009	DNA topoisomerase [bacterium OL-1].	22.69	542	353	19	65	588	109	602	2e-19	103
rs:WP_041645026	DNA topoisomerase I [Arcobacter butzleri].	24.50	645	360	25	7	605	5	568	2e-19	102
rs:WP_027253391	DNA topoisomerase I [Photobacterium halotolerans].	24.40	545	319	19	7	505	6	503	2e-19	103
rs:WP_011257487	DNA topoisomerase I [Xanthomonas oryzae].	23.52	591	352	18	7	563	6	530	2e-19	102
rs:WP_044828820	DNA topoisomerase I [Thalassospira sp. HJ].	26.20	542	307	24	4	505	1	489	2e-19	103
rs:WP_014159758	DNA topoisomerase I [Pseudoxanthomonas spadix].	24.58	590	347	20	7	563	6	530	2e-19	102
rs:WP_037597010	DNA topoisomerase I [Streptococcus sp. AS20].	24.11	531	306	18	7	504	16	482	2e-19	102
rs:WP_024745936	DNA topoisomerase I [Xanthomonas oryzae].	23.86	591	350	20	7	563	6	530	2e-19	102
rs:WP_037365465	DNA topoisomerase I [Selenomonas sp. FOBRC6].	24.32	629	365	28	7	599	51	604	2e-19	102
rs:WP_007546838	DNA topoisomerase I [Sulfurihydrogenibium yellowstonense].	24.00	575	360	17	1	563	1	510	2e-19	102
rs:WP_000179621	DNA topoisomerase I [Streptococcus sp. SK643].	24.52	522	315	18	7	504	17	483	2e-19	102
rs:WP_045721371	DNA topoisomerase I, partial [Salmonella enterica].	25.42	539	316	20	7	505	6	498	2e-19	102
rs:WP_028641269	DNA topoisomerase I [Novosphingobium acidiphilum].	25.14	553	297	25	7	510	4	488	2e-19	102
rs:WP_003613142	DNA topoisomerase I [Lactobacillus delbrueckii].	25.72	521	314	18	7	504	36	506	2e-19	102
rs:WP_020044548	DNA topoisomerase I [alpha proteobacterium SCGC AAA298-K06].	25.65	538	308	25	4	505	1	482	2e-19	102
rs:WP_014504887	DNA topoisomerase I [Xanthomonas oryzae].	23.86	591	350	20	7	563	6	530	2e-19	102
rs:WP_041501630	DNA topoisomerase I [Lactobacillus heilongjiangensis].	25.05	523	319	18	7	504	10	484	2e-19	102
rs:WP_038071896	DNA topoisomerase I [Thermus scotoductus].	25.22	567	298	24	7	505	1	509	2e-19	102
rs:WP_008278471	DNA topoisomerase I [Cyanothece sp. CCY0110].	25.78	446	278	15	104	519	77	499	2e-19	102
rs:WP_037624562	DNA topoisomerase I [Streptococcus uberis].	22.79	531	314	17	7	504	30	497	2e-19	102
rs:WP_036191546	DNA topoisomerase I [Lysobacter concretionis].	24.44	540	319	18	7	505	6	497	2e-19	102
tr:A0A0D5ZFV8_9ARCH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AKA48510.1};	23.70	540	337	20	28	553	40	518	2e-19	102
tr:U7RYE7_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.94	360	242	11	165	515	8	355	2e-19	99.8
rs:WP_027894204	DNA topoisomerase I [Meiothermus chliarophilus].	24.53	534	326	22	1	505	1	486	2e-19	102
rs:WP_033687089	DNA topoisomerase I [Streptococcus mitis].	24.81	524	305	20	10	504	2	465	2e-19	102
rs:WP_011310523	DNA topoisomerase I [Thiobacillus denitrificans].	27.63	427	261	16	107	505	75	481	2e-19	102
rs:WP_007193248	DNA topoisomerase I [Thiocapsa marina].	23.84	541	319	17	7	505	4	493	2e-19	102
rs:WP_006453157	DNA topoisomerase I [Xanthomonas gardneri].	24.32	592	346	20	7	563	6	530	3e-19	102
rs:WP_026756381	DNA topoisomerase I [Sediminimonas qiaohouensis].	25.09	554	307	25	4	510	1	493	3e-19	102
rs:WP_045354052	topoisomerase I, partial [Lactobacillus plantarum].	31.88	229	138	8	5	225	3	221	3e-19	97.8
rs:WP_026610181	DNA topoisomerase I [Methylocaldum szegediense].	25.28	542	308	20	7	505	6	493	3e-19	102
rs:WP_023169833	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	25.42	539	316	20	7	505	6	498	3e-19	102
rs:WP_013439705	DNA topoisomerase I [Lactobacillus delbrueckii].	25.53	521	315	18	7	504	36	506	3e-19	102
rs:WP_022525855	topoisomerase IA [Streptococcus anginosus].	24.62	528	307	19	7	504	16	482	3e-19	102
rs:WP_011747004	DNA topoisomerase I [Paracoccus denitrificans].	25.14	537	309	21	4	505	1	479	3e-19	102
rs:WP_036859048	DNA topoisomerase I, partial [Prevotella disiens].	25.94	347	216	9	5	333	3	326	3e-19	99.4
rs:WP_027069793	DNA topoisomerase I [Lysobacter defluvii].	24.77	541	315	20	7	505	6	496	3e-19	102
rs:WP_042527530	DNA topoisomerase I [Coxiella burnetii].	24.27	651	357	28	7	582	6	595	3e-19	102
rs:WP_004317674	DNA topoisomerase I [Campylobacter concisus].	26.70	442	274	15	89	505	59	475	3e-19	102
rs:WP_015778211	DNA topoisomerase I [Anaerococcus prevotii].	23.69	612	371	24	7	598	6	541	3e-19	102
rs:WP_036869692	DNA topoisomerase I, partial [Prevotella disiens].	26.32	342	211	10	5	333	3	316	3e-19	99.4
rs:WP_045224643	DNA topoisomerase I [Methylococcaceae bacterium 73a].	24.30	539	318	17	7	505	6	494	3e-19	102
rs:WP_009992334	DNA topoisomerase I [Sulfolobus solfataricus].	23.14	579	368	20	7	564	12	534	3e-19	102
rs:WP_022557737	hypothetical protein [Xanthomonas fuscans].	29.75	242	156	6	8	249	5	232	3e-19	99.0
rs:WP_002836341	DNA topoisomerase I [Finegoldia magna].	24.48	527	327	17	1	505	1	478	3e-19	102
rs:WP_034058858	DNA topoisomerase I [Pseudomonas aeruginosa].	24.38	525	326	16	43	545	16	491	3e-19	102
rs:WP_013302117	DNA topoisomerase I [Mycoplasma hyorhinis].	23.54	514	323	20	7	504	10	469	3e-19	102
tr:U2KBX5_9BACT	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:ERJ72353.1};	26.32	342	211	10	5	333	3	316	3e-19	99.4
rs:WP_039431940	DNA topoisomerase I [Xanthomonas vasicola].	23.99	592	348	20	7	563	6	530	3e-19	102
rs:WP_003623892	DNA topoisomerase I [Lactobacillus delbrueckii].	25.72	521	314	18	7	504	39	509	3e-19	102
rs:WP_026472027	DNA topoisomerase I [Alkanindiges illinoisensis].	25.92	436	283	14	88	505	125	538	3e-19	102
tr:W1WYM7_9FIRM	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ETJ23046.1}; Flags: Fragment;	26.77	269	185	6	8	273	5	264	3e-19	98.6
rs:WP_021183094	DNA topoisomerase I [Pantoea sp. AS-PWVM4].	27.29	436	275	15	88	505	88	499	3e-19	102
rs:WP_018972214	DNA topoisomerase I [Rudaea cellulosilytica].	25.34	592	340	23	7	563	6	530	3e-19	102
tr:A0A081PQQ6_STRMT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.92	436	265	15	97	504	31	436	3e-19	102
tr:A0A091CCP3_9ENTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.81	532	309	19	7	504	7	481	3e-19	102
rs:WP_018233248	DNA topoisomerase I [Thioalkalivibrio thiocyanodenitrificans].	26.08	533	316	19	7	505	6	494	3e-19	102
rs:WP_006597227	DNA topoisomerase I [Streptococcus australis].	25.62	527	297	23	10	504	2	465	3e-19	102
rs:WP_039574954	DNA topoisomerase III, partial [Xanthomonas axonopodis].	30.09	226	147	5	8	233	5	219	3e-19	97.4
tr:R4BEW2_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOM38169.1};	31.95	241	142	7	329	557	2	232	3e-19	100
rs:WP_009138456	DNA topoisomerase [Slackia piriformis].	22.68	538	341	15	66	581	109	593	3e-19	102
rs:WP_041093558	DNA topoisomerase I [Lactobacillus hokkaidonensis].	26.72	524	305	23	7	504	27	497	3e-19	102
rs:WP_033481886	MULTISPECIES: DNA topoisomerase III, partial [Xanthomonas].	30.09	226	147	5	8	233	5	219	3e-19	97.4
rs:WP_046550239	DNA topoisomerase I [Sulfurovum lithotrophicum].	27.33	439	259	16	97	505	69	477	3e-19	102
rs:WP_023409931	hypothetical protein [uncultured Thiohalocapsa sp. PB-PSB1].	26.10	272	176	8	312	561	2	270	3e-19	100
rs:WP_019864876	DNA topoisomerase I [Methylovulum miyakonense].	26.30	597	327	25	7	562	6	530	3e-19	102
rs:WP_003658699	topoisomerase I [Moraxella catarrhalis].	24.95	529	325	20	88	596	104	580	3e-19	102
rs:WP_031234877	DNA topoisomerase III, partial [Salmonella enterica].	28.27	283	178	9	296	557	1	279	3e-19	99.0
rs:WP_010776959	DNA topoisomerase III, partial [Enterococcus faecium].	26.63	353	244	8	201	544	13	359	3e-19	100
rs:WP_039980895	DNA topoisomerase I [Selenomonas sp. oral taxon 149].	26.50	532	301	26	7	505	34	508	3e-19	102
tr:A9MQ04_SALAR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.05	535	323	19	7	505	6	498	3e-19	102
rs:WP_009294935	DNA topoisomerase I [Campylobacter sp. 10_1_50].	27.60	442	270	16	89	505	59	475	3e-19	102
rs:WP_020104497	DNA topoisomerase I [Mycoplasma hyorhinis].	23.54	514	323	20	7	504	10	469	3e-19	101
rs:WP_028950752	DNA topoisomerase I [Sulfurihydrogenibium subterraneum].	23.93	631	365	24	7	607	5	550	3e-19	102
rs:WP_008890785	DNA topoisomerase I [Thalassospira profundimaris].	25.65	538	315	21	4	505	1	489	3e-19	102
rs:WP_023926566	hypothetical protein [Prevotella nigrescens].	25.96	339	216	9	5	333	3	316	3e-19	99.0
rs:WP_038395914	DNA topoisomerase I [Salmonella enterica].	25.05	535	323	19	7	505	6	498	3e-19	102
rs:WP_021770527	DNA topoisomerase I [Mitsuokella sp. oral taxon 131].	25.65	581	332	25	5	553	40	552	3e-19	102
rs:WP_014513937	DNA topoisomerase I [Sulfolobus islandicus].	23.02	582	366	20	7	564	12	535	3e-19	102
rs:WP_018661545	DNA topoisomerase I [Thermobrachium celere].	24.36	628	373	23	7	606	6	559	3e-19	102
rs:WP_014563693	DNA topoisomerase I [Lactobacillus helveticus].	24.62	524	318	17	7	505	19	490	4e-19	102
rs:WP_042605792	DNA topoisomerase III, partial [Vibrio harveyi].	27.10	321	218	8	8	322	5	315	4e-19	99.0
tr:E1GTM7_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EFN91994.1};	26.54	309	193	12	262	553	13	304	4e-19	100
rs:WP_020021509	hypothetical protein [alpha proteobacterium SCGC AAA536-G10].	26.81	526	311	21	7	505	4	482	4e-19	102
rs:WP_042510470	DNA topoisomerase I [Moraxella catarrhalis].	24.95	529	325	20	88	596	104	580	4e-19	102
rs:WP_035052659	DNA topoisomerase I [Carnobacterium pleistocenium].	25.00	532	320	19	1	504	1	481	4e-19	102
tr:T0MS31_9SPHI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.73	355	205	11	4	337	1	328	4e-19	99.0
rs:WP_019768655	DNA topoisomerase I [Streptococcus sobrinus].	24.10	527	312	18	7	504	33	500	4e-19	102
rs:WP_009546432	MULTISPECIES: DNA topoisomerase I [Cyanothece].	25.64	429	263	13	107	504	85	488	4e-19	102
rs:WP_045846408	DNA topoisomerase I [Aquitalea magnusonii].	25.82	546	311	20	7	510	6	499	4e-19	102
rs:WP_044119010	DNA topoisomerase III, partial [Staphylococcus aureus].	30.67	300	191	9	5	298	3	291	4e-19	98.6
rs:WP_003672057	topoisomerase I [Moraxella catarrhalis].	24.95	529	325	20	88	596	104	580	4e-19	102
rs:WP_003657116	topoisomerase I [Moraxella catarrhalis].	24.95	529	325	20	88	596	104	580	4e-19	102
tr:F9P671_STRCV	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.15	517	289	20	7	492	1	450	4e-19	100
rs:WP_002839237	DNA topoisomerase, partial [Finegoldia magna].	26.01	346	222	11	273	604	1	326	4e-19	99.0
rs:WP_022319904	DNA topoisomerase [Clostridium sp. CAG:349].	24.62	597	332	22	7	557	6	530	4e-19	102
rs:WP_031921849	DNA topoisomerase III, partial [Staphylococcus aureus].	31.84	223	139	7	5	221	3	218	4e-19	97.8
rs:WP_036864533	DNA topoisomerase I, partial [Prevotella bivia].	26.74	344	207	11	5	333	3	316	4e-19	99.0
rs:WP_046407983	DNA topoisomerase I [Sphingomonas sp. Ag1].	26.63	522	309	23	7	505	4	474	4e-19	102
rs:WP_038046302	hypothetical protein [Thermoanaerobaculum aquaticum].	24.77	541	306	21	7	506	6	486	4e-19	102
rs:WP_039688410	DNA topoisomerase [Coriobacteriaceae bacterium 68-1-3].	22.80	557	375	15	65	607	108	623	4e-19	102
rs:WP_016427618	DNA topoisomerase 1 [Paenisporosarcina sp. HGH0030].	27.46	426	249	15	112	504	82	480	4e-19	102
rs:WP_046653556	DNA topoisomerase I [Brevundimonas diminuta].	25.82	546	314	22	7	510	4	500	4e-19	102
rs:WP_003106911	DNA topoisomerase I [Streptococcus parauberis].	24.28	523	316	16	7	504	30	497	4e-19	102
rs:WP_003663911	topoisomerase I [Moraxella catarrhalis].	24.95	529	325	20	88	596	104	580	4e-19	102
rs:WP_019770716	DNA topoisomerase I [Streptococcus sobrinus].	24.19	525	314	18	7	504	33	500	4e-19	102
rs:WP_045607034	DNA topoisomerase I [Streptococcus mitis].	24.67	527	308	20	7	504	17	483	4e-19	102
rs:WP_039207818	hypothetical protein, partial [Anaerovibrio lipolyticus].	26.02	538	305	24	107	599	107	596	4e-19	102
rs:WP_039190177	DNA topoisomerase I [Aureimonas altamirensis].	25.64	550	310	24	4	505	1	499	4e-19	102
rs:WP_045814401	DNA topoisomerase I [Pantoea sp. SM3].	26.15	455	294	15	69	505	68	498	4e-19	102
rs:WP_014512616	DNA topoisomerase I [Sulfolobus islandicus].	23.15	540	340	18	42	564	53	534	4e-19	101
rs:WP_018368536	DNA topoisomerase I [Streptococcus entericus].	24.90	526	309	19	7	504	17	484	4e-19	101
tr:A7ZFR7_CAMC1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.60	442	270	16	89	505	59	475	4e-19	102
rs:WP_024299256	DNA topoisomerase I [Methylosarcina lacus].	25.25	590	341	20	7	562	6	529	4e-19	102
rs:WP_029775121	DNA topoisomerase I, partial [delta proteobacterium JGI 0000059-J07].	25.38	528	315	19	7	505	2	479	4e-19	102
rs:WP_003626499	DNA topoisomerase I [Lactobacillus helveticus].	24.62	524	318	17	7	505	19	490	4e-19	101
rs:WP_025283551	DNA topoisomerase I [Lactobacillus helveticus].	24.62	524	318	17	7	505	19	490	4e-19	101
tr:J3HUJ6_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.22	287	179	9	283	550	15	293	4e-19	101
rs:WP_023920771	DNA topoisomerase I [Rhodobacter capsulatus].	25.38	528	317	20	4	505	1	477	4e-19	102
rs:WP_008442944	DNA topoisomerase I [Halorubrum californiense].	21.88	544	346	17	7	498	8	524	4e-19	102
rs:WP_015117455	DNA topoisomerase I [Rivularia sp. PCC 7116].	24.85	499	308	15	89	561	64	521	4e-19	102
rs:WP_031877508	DNA topoisomerase III, partial [Staphylococcus aureus].	31.84	223	139	7	5	221	3	218	4e-19	97.8
tr:A0A0C7E5F3_XANCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	592	348	20	7	563	6	530	4e-19	102
tr:A0A0A7U047_LACBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.62	528	313	21	7	505	23	494	4e-19	101
rs:WP_033858482	DNA topoisomerase III, partial [Staphylococcus aureus].	31.84	223	139	7	5	221	3	218	4e-19	97.8
rs:WP_023061818	DNA topoisomerase [Lactobacillus helveticus].	24.62	524	318	17	7	505	19	490	4e-19	101
rs:WP_023198122	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	25.42	539	316	20	7	505	6	498	4e-19	101
rs:WP_037368858	DNA topoisomerase I [Selenomonas ruminantium].	25.12	609	345	28	7	580	34	566	4e-19	102
rs:WP_003042684	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.11	531	306	18	7	504	16	482	4e-19	101
rs:WP_037364714	DNA topoisomerase I [Selenomonas ruminantium].	25.86	611	342	28	5	580	33	567	4e-19	102
rs:WP_018939267	DNA topoisomerase I [Thioalkalivibrio sp. AKL11].	25.70	537	313	22	7	505	6	494	4e-19	102
tr:F3PYL3_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.65	574	365	19	4	550	10	531	4e-19	101
tr:B1X1Z5_CYAA5	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.64	429	263	13	107	504	100	503	4e-19	101
rs:WP_046814120	DNA topoisomerase I [Lactobacillus helveticus].	24.62	524	318	17	7	505	19	490	4e-19	101
rs:WP_044757939	DNA topoisomerase, partial [Streptococcus suis].	27.25	356	237	11	165	509	8	352	4e-19	99.0
rs:WP_023376403	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	25.42	539	316	20	7	505	6	498	4e-19	101
rs:WP_037330088	hypothetical protein, partial [Anaerovibrio lipolyticus].	25.00	640	358	29	5	599	44	606	4e-19	102
rs:WP_019023224	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	25.51	537	314	22	7	505	6	494	4e-19	102
rs:WP_019781670	DNA topoisomerase I [Streptococcus sobrinus].	24.10	527	312	18	7	504	33	500	4e-19	101
rs:WP_028798425	DNA topoisomerase I [Streptococcus sobrinus].	24.43	528	309	19	7	504	33	500	4e-19	101
rs:WP_036365716	DNA topoisomerase I [Moraxella bovoculi].	25.17	437	280	15	88	505	106	514	4e-19	102
rs:WP_036486938	DNA topoisomerase I, partial [Myxosarcina sp. GI1].	25.19	528	316	17	91	590	66	542	4e-19	101
tr:K1TYJ3_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78082.1}; Flags: Fragment;	27.91	301	188	8	7	306	4	276	4e-19	98.2
rs:WP_012814316	DNA topoisomerase I [Candidatus Methylomirabilis oxyfera].	24.54	546	314	22	7	505	6	500	4e-19	102
rs:WP_039743749	DNA topoisomerase I [Geobacter pickeringii].	25.33	533	316	18	7	505	6	490	4e-19	101
rs:WP_031879277	DNA topoisomerase III, partial [Staphylococcus aureus].	31.84	223	139	7	5	221	3	218	4e-19	97.4
rs:WP_046736113	DNA topoisomerase III, partial [Xanthomonas axonopodis].	30.09	226	147	5	8	233	5	219	4e-19	97.4
rs:WP_003108440	DNA topoisomerase I [Streptococcus parauberis].	24.28	523	316	16	7	504	30	497	4e-19	101
rs:WP_036737880	DNA topoisomerase I [Paracoccus halophilus].	25.42	531	315	19	4	505	1	479	4e-19	102
rs:WP_035078850	DNA topoisomerase I [Devosia riboflavina].	26.73	535	308	22	4	505	1	484	4e-19	102
rs:WP_003034456	DNA topoisomerase I [Streptococcus anginosus].	24.11	531	306	18	7	504	16	482	4e-19	101
rs:WP_038052939	DNA topoisomerase I [Thioalkalivibrio sp. ALJ1].	25.70	537	313	22	7	505	6	494	4e-19	102
rs:WP_027443042	DNA topoisomerase I [Porphyrobacter cryptus].	26.53	539	288	25	7	505	4	474	4e-19	102
rs:WP_019785014	DNA topoisomerase I [Streptococcus sobrinus].	24.19	525	314	18	7	504	33	500	4e-19	101
rs:WP_035210349	hypothetical protein, partial [Acidithiobacillus thiooxidans].	25.11	466	282	16	75	505	37	470	4e-19	101
tr:D4KBC0_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.49	351	216	11	203	539	20	349	4e-19	100
rs:WP_033624486	DNA topoisomerase, partial [Enterococcus faecalis].	25.48	361	251	9	147	498	9	360	4e-19	99.0
rs:WP_014345297	DNA topoisomerase I [Sulfobacillus acidophilus].	26.75	542	294	28	7	504	8	490	4e-19	101
rs:WP_033396689	hypothetical protein, partial [Thermodesulfobacterium thermophilum].	26.06	564	323	24	7	553	6	492	4e-19	101
rs:WP_040501928	DNA topoisomerase III, partial [Herbaspirillum sp. YR522].	28.22	287	179	9	283	550	15	293	4e-19	101
rs:WP_021084556	DNA topoisomerase I [Campylobacter concisus].	26.70	442	274	15	89	505	59	475	4e-19	101
rs:WP_008522909	DNA topoisomerase I [Jonquetella anthropi].	25.42	535	311	18	5	505	118	598	4e-19	102
rs:WP_036171681	DNA topoisomerase I [Lysinibacillus massiliensis].	26.89	424	255	16	112	504	82	481	4e-19	101
rs:WP_023184162	DNA topoisomerase I subunit omega [Salmonella enterica].	25.97	539	313	21	7	505	6	498	5e-19	102
rs:WP_038060592	hypothetical protein, partial [Thermodesulfobacterium commune].	26.27	571	324	25	7	557	6	499	5e-19	101
tr:U1MJ04_9EURY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.02	545	348	17	7	526	5	497	5e-19	101
rs:WP_014784854	DNA topoisomerase [Terriglobus roseus].	25.31	569	308	24	7	510	6	522	5e-19	102
rs:WP_035217216	hypothetical protein, partial [Acidithiobacillus thiooxidans].	25.11	466	282	16	75	505	37	470	5e-19	101
rs:WP_043746353	DNA topoisomerase I [Oceanicola sp. 22II-S11g].	26.97	534	305	23	4	505	1	481	5e-19	102
tr:W0E1F8_MARPU	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:AHF04680.1};	30.98	184	116	1	358	530	1	184	5e-19	98.6
rs:WP_016971647	topoisomerase I [Pseudomonas tolaasii].	23.88	582	371	19	43	603	30	560	5e-19	101
rs:WP_023253082	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	25.42	539	316	20	7	505	6	498	5e-19	101
rs:WP_045098244	DNA topoisomerase I [Tatlockia micdadei].	25.98	535	313	18	7	505	6	493	5e-19	101
tr:X1KIM1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C00809 {ECO:0000313|EMBL:GAH89974.1}; Flags: Fragment;	26.21	538	309	22	7	504	3	492	5e-19	101
rs:WP_039969953	DNA topoisomerase I [Bacteroides fluxus].	22.65	574	365	19	4	550	1	522	5e-19	101
rs:WP_021775997	DNA topoisomerase I [Jonquetella sp. BV3C21].	25.42	535	311	18	5	505	118	598	5e-19	101
rs:WP_013524908	DNA topoisomerase I [Thermovibrio ammonificans].	24.83	572	333	24	7	561	3	494	5e-19	101
rs:WP_018141432	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	25.88	541	307	22	7	505	6	494	5e-19	101
rs:WP_031887218	DNA topoisomerase III, partial [Staphylococcus aureus].	31.84	223	139	7	5	221	3	218	5e-19	97.8
tr:E0NXP6_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.50	532	301	26	7	505	48	522	5e-19	101
rs:WP_028722826	DNA topoisomerase I [Pantoea ananatis].	27.13	457	287	16	69	505	68	498	5e-19	101
rs:WP_037356697	DNA topoisomerase I [Selenomonas sp. FC4001].	25.12	609	345	28	7	580	34	566	5e-19	101
rs:WP_038625919	DNA topoisomerase I [Pantoea sp. PSNIH2].	24.62	528	331	17	7	505	6	495	5e-19	101
rs:WP_046699395	DNA topoisomerase I [Moraxella bovoculi].	25.17	437	280	15	88	505	106	514	5e-19	101
rs:WP_009470741	topoisomerase I [gamma proteobacterium HIMB55].	22.39	545	336	17	7	505	6	509	5e-19	101
rs:WP_021795786	hypothetical protein [Thermoplasmatales archaeon A-plasma].	24.28	523	317	19	48	550	57	520	5e-19	101
rs:WP_022698960	DNA topoisomerase I [Maricaulis sp. JL2009].	26.52	528	309	21	4	505	1	475	5e-19	101
rs:WP_019776889	DNA topoisomerase I [Streptococcus sobrinus].	24.10	527	312	18	7	504	33	500	5e-19	101
rs:WP_009821529	DNA topoisomerase I [Sphingomonas sp. SKA58].	25.62	523	313	20	7	505	4	474	5e-19	101
rs:WP_018465097	hypothetical protein [Meiothermus timidus].	24.91	538	322	22	1	505	1	489	5e-19	101
rs:WP_027976116	DNA topoisomerase I [Streptococcus devriesei].	25.10	522	313	19	7	504	24	491	5e-19	101
tr:E6J331_STRAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.11	531	306	18	7	504	19	485	5e-19	101
rs:WP_016174777	DNA topoisomerase 1 [Enterococcus saccharolyticus].	24.25	532	324	17	1	504	1	481	5e-19	101
rs:WP_036762982	DNA topoisomerase I [Peptostreptococcus sp. MV1].	23.23	637	376	26	7	607	6	565	5e-19	101
rs:WP_035184592	DNA topoisomerase I [Lactobacillus delbrueckii].	25.53	521	315	18	7	504	36	506	6e-19	101
tr:U2ILG3_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.10	527	312	18	7	504	35	502	6e-19	101
rs:WP_013068797	DNA topoisomerase I [Rhodobacter capsulatus].	25.19	528	318	20	4	505	1	477	6e-19	101
rs:WP_029520244	DNA topoisomerase I [Persephonella sp. IF05-L8].	22.97	553	350	16	7	550	8	493	6e-19	101
rs:WP_035266776	DNA topoisomerase I [Acinetobacter sp. Ver3].	24.39	537	323	17	7	505	26	517	6e-19	101
rs:WP_023918843	DNA topoisomerase I [Rhodobacter capsulatus].	25.19	528	318	20	4	505	1	477	6e-19	101
rs:WP_038041147	DNA topoisomerase I [Thermus yunnanensis].	24.49	539	326	20	2	505	23	515	6e-19	101
rs:WP_046697158	DNA topoisomerase I [Moraxella bovoculi].	25.17	437	280	15	88	505	106	514	6e-19	101
rs:WP_007125556	DNA topoisomerase I [Lactobacillus ultunensis].	24.24	524	320	18	7	505	19	490	6e-19	101
rs:WP_021228023	DNA topoisomerase I [Sphingobium lactosutens].	26.00	523	311	20	7	505	4	474	6e-19	101
rs:WP_000246607	DNA topoisomerase I [Streptococcus agalactiae].	24.86	519	318	19	7	504	25	492	6e-19	101
rs:WP_046344689	DNA topoisomerase I [Xanthomonas campestris].	23.99	592	348	20	7	563	6	530	6e-19	101
tr:E6QVF7_9ZZZZ	SubName: Full=DNA topoisomerase 1 (DNA topoisomerase I) (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) {ECO:0000313|EMBL:CBI11230.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI11230.1};	26.93	557	298	25	5	510	3	501	6e-19	101
rs:WP_033935563	DNA topoisomerase I [Lactobacillus mucosae].	25.43	523	313	22	7	504	42	512	6e-19	101
tr:W7ASG1_9LIST	SubName: Full=Topoisomerase IA {ECO:0000313|EMBL:EUJ16552.1};	28.69	251	161	6	5	247	3	243	6e-19	97.8
rs:WP_021088986	DNA topoisomerase I [Campylobacter concisus].	27.60	442	270	16	89	505	59	475	6e-19	101
rs:WP_003547140	DNA topoisomerase I [Lactobacillus acidophilus].	23.85	524	322	18	7	505	19	490	6e-19	101
rs:WP_023212465	DNA topoisomerase I subunit omega [Salmonella enterica].	25.97	539	313	21	7	505	6	498	6e-19	101
rs:WP_016182471	DNA topoisomerase 1 [Enterococcus columbae].	24.14	526	320	16	7	504	7	481	6e-19	101
rs:WP_043763722	DNA topoisomerase, partial [Marichromatium purpuratum].	32.75	171	104	1	371	530	3	173	6e-19	98.2
rs:WP_012220043	DNA topoisomerase I [Coxiella burnetii].	24.12	651	358	28	7	582	6	595	6e-19	101
rs:WP_040941924	DNA topoisomerase I [Xanthomonas campestris].	23.82	592	349	20	7	563	6	530	6e-19	101
rs:WP_021774356	DNA topoisomerase I [Oribacterium sp. oral taxon 078].	24.48	527	320	18	7	505	6	482	6e-19	101
rs:WP_021087516	DNA topoisomerase I [Campylobacter concisus].	27.60	442	270	16	89	505	59	475	6e-19	101
rs:WP_040228112	DNA topoisomerase I [Bhargavaea cecembensis].	25.28	538	298	21	7	504	6	479	6e-19	101
rs:WP_045832147	DNA topoisomerase I [Pantoea sp. BL1].	26.15	455	294	15	69	505	68	498	6e-19	101
rs:WP_021167566	DNA topoisomerase 1 [Sporomusa ovata].	24.86	539	312	19	7	505	6	491	6e-19	101
rs:WP_025056227	DNA topoisomerase I [Sulfitobacter sp. NB-77].	25.28	538	308	23	4	505	1	480	6e-19	101
rs:WP_039944916	DNA topoisomerase I [Lactobacillus mucosae].	25.43	523	313	22	7	504	42	512	7e-19	101
rs:WP_014032176	DNA topoisomerase I [Muricauda ruestringensis].	24.90	518	310	18	7	504	6	464	7e-19	101
rs:WP_014621523	DNA topoisomerase I [Streptococcus thermophilus].	24.47	523	314	18	7	504	32	498	7e-19	101
rs:WP_039879571	DNA topoisomerase I [Jonquetella anthropi].	24.95	533	316	18	5	505	118	598	7e-19	101
rs:WP_045716645	DNA topoisomerase I, partial [Salmonella enterica].	25.79	539	314	21	7	505	6	498	7e-19	101
tr:C0N5G6_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.25	532	325	18	7	504	19	506	7e-19	101
rs:WP_043888070	DNA topoisomerase I [Methylophaga thiooxydans].	24.20	533	326	18	7	505	6	494	7e-19	101
rs:WP_038646692	DNA topoisomerase I [Pantoea rwandensis].	26.15	455	294	15	69	505	68	498	7e-19	101
rs:WP_042513650	hypothetical protein [Bacillus anthracis].	29.29	280	171	10	295	556	2	272	7e-19	98.6
rs:WP_006352524	DNA topoisomerase I [Lactobacillus amylolyticus].	24.71	526	319	18	5	505	17	490	7e-19	100
rs:WP_040919489	DNA topoisomerase I, partial [Leptonema illini].	24.23	582	324	21	5	553	30	527	7e-19	100
rs:WP_003171354	DNA topoisomerase III [Bacillus anthracis].	29.50	278	169	10	295	554	2	270	7e-19	99.0
rs:WP_043087498	DNA topoisomerase I [Xanthomonas arboricola].	23.99	592	348	20	7	563	6	530	7e-19	101
rs:WP_003105989	DNA topoisomerase I [Streptococcus parauberis].	24.28	523	316	16	7	504	30	497	7e-19	100
rs:WP_029221354	DNA topoisomerase I [Xanthomonas cassavae].	23.65	592	350	18	7	563	6	530	7e-19	101
rs:WP_016480750	DNA topoisomerase I [Streptococcus agalactiae].	24.86	519	318	19	7	504	25	492	7e-19	100
rs:WP_038519001	DNA topoisomerase I [Moraxella catarrhalis].	24.95	529	325	20	88	596	104	580	7e-19	101
rs:WP_020967061	DNA topoisomerase I [Chlamydia trachomatis].	25.95	555	324	22	46	563	30	534	7e-19	101
rs:WP_011643221	DNA topoisomerase I [Maricaulis maris].	25.14	549	317	23	4	510	1	497	7e-19	101
rs:WP_004511123	DNA topoisomerase I [Arcobacter butzleri].	24.34	645	361	25	7	605	5	568	7e-19	101
rs:WP_046964308	DNA topoisomerase I [Xanthomonas pisi].	23.99	592	348	20	7	563	6	530	7e-19	101
rs:WP_045874334	DNA topoisomerase I [Tolypothrix sp. PCC 7601].	24.75	497	311	16	89	561	64	521	7e-19	101
rs:WP_035305590	DNA topoisomerase, partial [Clostridium sp. HMP27].	28.01	332	209	11	279	590	4	325	7e-19	99.8
rs:WP_026817248	DNA topoisomerase I [Arenimonas composti].	24.45	593	354	21	7	568	6	535	7e-19	101
rs:WP_002839112	DNA topoisomerase I [Finegoldia magna].	24.48	527	327	17	1	505	1	478	7e-19	100
rs:WP_040304038	DNA topoisomerase I, partial [Campylobacter gracilis].	25.51	443	276	13	89	505	59	473	7e-19	100
rs:WP_040653704	DNA topoisomerase I, partial [Oribacterium sp. oral taxon 078].	24.48	527	320	18	7	505	6	482	7e-19	100
rs:WP_047127472	DNA topoisomerase I [Xanthomonas arboricola].	23.99	592	348	20	7	563	6	530	7e-19	101
tr:J1JMX7_STREE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.10	433	268	15	97	504	31	436	7e-19	100
tr:V2KZL9_SALET	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.42	539	316	20	7	505	6	498	7e-19	100
rs:WP_031883560	DNA topoisomerase III, partial [Staphylococcus aureus].	26.20	313	200	10	7	315	5	290	7e-19	97.4
rs:WP_024938530	DNA topoisomerase I [Xanthomonas arboricola].	23.99	592	348	20	7	563	6	530	7e-19	101
tr:D7WI62_BACCE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFI65102.1};	24.76	412	265	12	43	429	43	434	7e-19	99.4
rs:WP_017793097	DNA topoisomerase I [Leucobacter salsicius].	25.13	561	313	23	7	505	8	523	7e-19	101
rs:WP_039677107	DNA topoisomerase I [Streptococcus constellatus].	23.92	531	307	18	7	504	16	482	7e-19	100
rs:WP_001527825	topoisomerase I [Salmonella enterica].	25.97	539	313	21	7	505	6	498	7e-19	101
rs:WP_039815909	DNA topoisomerase I [Xanthomonas arboricola].	23.99	592	348	20	7	563	6	530	7e-19	101
rs:WP_014030375	DNA topoisomerase I [Acidithiobacillus ferrivorans].	24.90	494	300	20	57	505	14	481	8e-19	100
rs:WP_038247321	DNA topoisomerase I [Zetaproteobacteria bacterium TAG-1].	25.63	558	311	22	1	510	1	502	8e-19	100
rs:WP_000513597	topoisomerase I [Salmonella enterica].	25.51	537	318	20	7	505	6	498	8e-19	101
rs:WP_012290577	DNA topoisomerase I [Finegoldia magna].	24.48	527	327	17	1	505	1	478	8e-19	100
rs:XP_009367980	PREDICTED: uncharacterized protein LOC103957527 isoform X1 [Pyrus x bretschneideri].	26.60	530	299	22	36	505	371	870	8e-19	101
rs:WP_031915409	DNA topoisomerase III, partial [Staphylococcus aureus].	26.28	312	199	10	7	314	5	289	8e-19	97.4
rs:WP_019254030	DNA topoisomerase I [Lactobacillus reuteri].	24.76	525	314	19	7	504	25	495	8e-19	100
rs:WP_016902511	DNA topoisomerase I [Xanthomonas arboricola].	23.99	592	348	20	7	563	6	530	8e-19	101
rs:WP_024782601	DNA topoisomerase I [Streptococcus mutans].	24.38	521	318	19	7	504	24	491	8e-19	100
rs:WP_033095677	DNA topoisomerase I [Colwellia psychrerythraea].	25.60	543	316	20	7	505	6	504	8e-19	101
tr:H2CDW9_9LEPT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.57	582	322	22	5	553	51	548	8e-19	100
rs:WP_040914528	hypothetical protein, partial [Lentisphaera araneosa].	24.33	559	318	21	1	510	1	503	8e-19	100
rs:WP_019518815	topoisomerase I [Moraxella boevrei].	25.35	568	337	20	7	541	38	551	8e-19	101
gp:FP929058_741	DNA topoisomerase I [Enterococcus sp. 7L76]	24.33	526	319	18	7	504	7	481	8e-19	100
rs:WP_039332040	DNA topoisomerase I [Novosphingobium subterraneum].	26.67	540	289	24	7	505	4	477	8e-19	101
tr:G5Q277_SALMO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.97	539	313	21	7	505	6	498	8e-19	100
rs:WP_039446947	DNA topoisomerase I [Xanthomonas vasicola].	23.99	592	348	20	7	563	6	530	8e-19	101
rs:WP_042595233	DNA topoisomerase I [Xanthomonas campestris].	23.82	592	349	20	7	563	6	530	8e-19	101
rs:WP_045161401	DNA topoisomerase I [Salmonella enterica].	25.51	537	318	20	7	505	6	498	8e-19	101
rs:WP_018111526	DNA topoisomerase I [Thermus igniterrae].	25.09	530	322	19	7	505	2	487	8e-19	100
rs:WP_028790321	DNA topoisomerase I [Tetragenococcus muriaticus].	24.81	532	309	19	7	504	7	481	8e-19	100
rs:WP_025022073	DNA topoisomerase I [Lactobacillus hayakitensis].	24.62	524	316	21	7	504	23	493	8e-19	100
rs:WP_009429851	DNA topoisomerase I [Oribacterium sp. oral taxon 108].	25.43	527	312	21	7	504	6	480	8e-19	100
rs:NP_639100	DNA topoisomerase I [Xanthomonas campestris pv. campestris str. ATCC 33913].	23.82	592	349	20	7	563	6	530	8e-19	100
gp:CP002165_2004	DNA topoisomerase [Xylella fastidiosa subsp. fastidiosa GB514]	28.32	279	185	8	64	336	23	292	8e-19	97.4
gp:CP003231_259	DNA topoisomerase I [Mycoplasma hyorhinis GDL-1]	23.74	514	322	20	7	504	5	464	8e-19	100
rs:WP_019819801	hypothetical protein, partial [Vibrio splendidus].	35.53	197	121	5	200	391	9	204	8e-19	95.9
rs:WP_007119147	DNA topoisomerase I [Oceanibulbus indolifex].	25.18	552	307	25	4	510	1	491	8e-19	101
rs:WP_039524995	DNA topoisomerase I [Xanthomonas arboricola].	23.99	592	348	20	7	563	6	530	8e-19	100
rs:WP_002386831	DNA topoisomerase I, partial [Enterococcus faecalis].	24.33	526	319	18	7	504	7	481	8e-19	100
rs:WP_033082724	DNA topoisomerase I [Colwellia psychrerythraea].	25.37	544	316	19	7	505	6	504	8e-19	101
rs:WP_004578652	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	25.51	537	318	20	7	505	6	498	9e-19	100
rs:WP_015072720	DNA topoisomerase I [Gluconobacter oxydans].	25.68	549	313	25	7	510	5	503	9e-19	101
rs:WP_013509246	topoisomerase I [Pantoea sp. At-9b].	27.29	436	275	15	88	505	88	499	9e-19	100
rs:WP_029523172	DNA topoisomerase I [Persephonella sp. KM09-Lau-8].	23.15	553	349	16	7	550	8	493	9e-19	100
rs:WP_043104942	DNA topoisomerase I [Xanthomonas arboricola].	23.99	592	348	20	7	563	6	530	9e-19	100
rs:WP_031610507	DNA topoisomerase III, partial [Salmonella enterica].	30.71	254	151	6	312	544	1	250	9e-19	99.0
rs:WP_009643973	DNA topoisomerase, partial [Mogibacterium sp. CM50].	30.60	268	155	9	284	539	2	250	9e-19	97.8
rs:WP_023908201	DNA topoisomerase I [Xylella fastidiosa].	25.20	508	306	16	73	555	45	503	9e-19	100
rs:WP_032821592	topoisomerase I, partial [Oenococcus oeni].	30.25	238	152	6	5	236	3	232	9e-19	96.3
rs:WP_043901710	DNA topoisomerase I [Streptococcus sp. DORA_10].	25.69	436	266	15	97	504	63	468	9e-19	100
rs:WP_015631990	DNA topoisomerase I [Streptococcus agalactiae].	24.86	519	318	19	7	504	25	492	9e-19	100
rs:WP_006527281	DNA topoisomerase I [Gloeocapsa sp. PCC 73106].	25.59	469	281	16	88	515	63	504	9e-19	100
rs:WP_018996076	DNA topoisomerase I [Hirschia maritima].	26.27	552	302	25	4	510	1	492	9e-19	100
rs:WP_000246608	DNA topoisomerase I [Streptococcus agalactiae].	24.86	519	318	19	7	504	25	492	9e-19	100
rs:WP_034211709	DNA topoisomerase I [Arenimonas metalli].	24.49	592	345	24	7	563	6	530	9e-19	100
tr:D4CLC3_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.48	527	320	18	7	505	6	482	9e-19	100
rs:WP_010934214	DNA topoisomerase I [Corynebacterium diphtheriae].	26.13	463	282	17	86	505	75	520	9e-19	100
rs:WP_012109387	DNA topoisomerase I [Campylobacter hominis].	22.95	597	369	21	7	582	5	531	9e-19	100
rs:WP_008440553	DNA topoisomerase I, archaeal [Thaumarchaeota archaeon SCGC AB-539-E09].	24.90	522	329	24	1	495	1	486	9e-19	99.8
tr:K2EQB9_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	27.00	474	283	16	46	486	10	453	9e-19	99.4
rs:WP_036069502	DNA topoisomerase I [Listeria rocourtiae].	26.84	421	258	14	112	504	82	480	9e-19	100
rs:WP_016730808	DNA topoisomerase I [Sulfolobus islandicus].	23.06	581	366	20	7	564	12	534	9e-19	100
tr:V2BAJ7_SALET	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.95	537	321	19	7	505	6	498	9e-19	100
tr:A0A0D6PQ44_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN89483.1};	25.68	549	313	25	7	510	5	503	9e-19	100
rs:WP_022189573	DNA topoisomerase [Ruminococcus sp. CAG:177].	25.60	543	302	22	5	504	3	486	9e-19	100
tr:A0A0E1MML2_BACAN	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:AJH85612.1};	29.50	278	169	10	295	554	2	270	9e-19	99.0
rs:WP_007163929	DNA topoisomerase I [Erythrobacter sp. NAP1].	27.16	545	293	24	7	510	4	485	9e-19	100
tr:A0A081QGC6_STRMT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.69	436	266	15	97	504	31	436	9e-19	100
rs:WP_004278075	DNA topoisomerase I [Campylobacter upsaliensis].	24.49	486	310	17	47	505	21	476	9e-19	100
rs:WP_019773981	DNA topoisomerase I [Streptococcus sobrinus].	24.10	527	312	18	7	504	33	500	1e-18	100
rs:WP_004042619	DNA topoisomerase I, partial [Lactobacillus sp. ASF360].	23.85	524	322	18	7	505	18	489	1e-18	100
tr:F0R4F1_BACSH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	22.90	559	356	20	4	536	23	532	1e-18	100
tr:W7L256_XYLFS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.32	279	185	8	64	336	23	292	1e-18	97.4
rs:WP_014582537	DNA topoisomerase I [Mycoplasma hyorhinis].	23.74	514	322	20	7	504	10	469	1e-18	100
rs:WP_019795444	DNA topoisomerase I [Streptococcus sobrinus].	24.10	527	312	18	7	504	33	500	1e-18	100
rs:WP_007283133	DNA topoisomerase I [Gluconobacter thailandicus].	25.68	549	313	25	7	510	5	503	1e-18	100
rs:WP_033736007	DNA topoisomerase I [Helicobacter pylori].	26.95	449	264	16	89	505	59	475	1e-18	100
rs:WP_000681461	DNA topoisomerase I [Helicobacter pylori].	26.95	449	264	16	89	505	59	475	1e-18	100
rs:WP_012718809	DNA topoisomerase I [Sulfolobus islandicus].	23.06	581	366	20	7	564	12	534	1e-18	100
rs:WP_047207904	DNA topoisomerase I [Campylobacter lari].	23.93	514	318	16	7	500	6	466	1e-18	100
rs:WP_035442137	hypothetical protein [Bacillus sp. JCM 19046].	29.56	203	134	5	38	238	10	205	1e-18	95.9
rs:WP_014918887	DNA topoisomerase I [Lactobacillus helveticus].	24.43	524	319	17	7	505	19	490	1e-18	100
rs:WP_036109494	MULTISPECIES: DNA topoisomerase I [Luteibacter].	25.23	535	318	20	7	505	6	494	1e-18	100
rs:YP_001654102	DNA topoisomerase I [Chlamydia trachomatis 434/Bu].	25.95	555	324	22	46	563	30	534	1e-18	100
tr:W6P9Q2_9BACE	SubName: Full=DNA topoisomerase III, Bacteroidales-type {ECO:0000313|EMBL:CDM06736.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDM06736.1};	30.97	268	162	11	297	552	4	260	1e-18	98.6
rs:WP_032946806	MULTISPECIES: DNA topoisomerase I [Bacteroides].	22.34	564	353	21	4	536	1	510	1e-18	100
tr:H7QP91_STREE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.10	433	268	15	97	504	31	436	1e-18	100
rs:WP_046700364	DNA topoisomerase I [Moraxella bovoculi].	25.17	437	280	15	88	505	106	514	1e-18	100
rs:WP_007808660	DNA topoisomerase I [Rhodanobacter spathiphylli].	25.78	543	311	20	7	505	6	500	1e-18	100
tr:W1UK62_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.69	436	266	15	97	504	131	536	1e-18	100
rs:WP_040550400	DNA topoisomerase I [Pyramidobacter piscolens].	25.69	541	301	23	5	505	15	494	1e-18	100
rs:WP_012263525	DNA topoisomerase I [Chlamydia trachomatis].	25.95	555	324	22	46	563	30	534	1e-18	100
tr:A0A0D6Q8Q4_KOMXY	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN99809.1};	25.59	551	313	25	7	510	5	505	1e-18	100
rs:WP_029103165	DNA topoisomerase I [Moraxella caprae].	25.14	529	324	19	7	505	14	500	1e-18	100
rs:WP_015506487	DNA topoisomerase I/SWI domain fusion protein [Chlamydia trachomatis].	25.95	555	324	22	46	563	30	534	1e-18	100
rs:WP_038213506	DNA topoisomerase I [Xenophilus azovorans].	24.79	468	289	15	73	505	46	485	1e-18	100
rs:WP_035886894	DNA topoisomerase I [Legionella norrlandica].	25.42	535	317	16	7	505	6	494	1e-18	100
rs:WP_023427494	DNA topoisomerase I, archaeal [uncultured Acidilobus sp. OSP8].	24.69	559	344	20	6	541	14	518	1e-18	100
rs:WP_007476321	DNA topoisomerase I [Listeria fleischmannii].	27.01	422	256	16	112	504	82	480	1e-18	100
rs:WP_007544534	DNA topoisomerase I [Listeria fleischmannii].	26.78	422	257	16	112	504	82	480	1e-18	100
rs:WP_043696433	DNA topoisomerase I [Luteibacter sp. 9133].	26.17	535	313	21	7	505	6	494	1e-18	100
rs:WP_045391379	DNA topoisomerase I [Falsirhodobacter sp. alg1].	26.42	545	306	24	4	510	1	488	1e-18	100
rs:WP_002349400	DNA topoisomerase, partial [Enterococcus faecium].	30.08	266	164	8	314	563	12	271	1e-18	96.7
rs:WP_000513586	DNA topoisomerase I subunit omega [Salmonella enterica].	25.33	537	319	20	7	505	6	498	1e-18	100
rs:WP_027229115	DNA topoisomerase I [Legionella pneumophila].	25.05	535	319	15	7	505	6	494	1e-18	100
rs:WP_010393696	DNA topoisomerase I [Paracoccus sp. TRP].	25.93	536	306	22	4	505	1	479	1e-18	100
tr:G4NN22_CHLT4	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.95	555	324	22	46	563	43	547	1e-18	100
rs:WP_042746299	DNA topoisomerase I [Lactobacillus reuteri].	24.76	525	314	19	7	504	25	495	1e-18	100
rs:WP_015506113	DNA topoisomerase I/SWI domain fusion protein [Chlamydia trachomatis].	25.95	555	324	22	46	563	30	534	1e-18	100
rs:NP_220161	DNA topoisomerase I [Chlamydia trachomatis D/UW-3/CX].	25.95	555	324	22	46	563	30	534	1e-18	100
rs:WP_002841675	DNA topoisomerase I [Finegoldia magna].	24.48	527	327	17	1	505	1	478	1e-18	100
rs:WP_003666071	DNA topoisomerase I [Lactobacillus reuteri].	24.76	525	314	19	7	504	25	495	1e-18	100
rs:WP_020743415	DNA topoisomerase I subunit omega [Alteromonas macleodii].	26.45	431	276	14	93	505	99	506	1e-18	100
rs:WP_003674222	DNA topoisomerase I [Lactobacillus reuteri].	24.71	522	318	18	7	504	25	495	1e-18	100
rs:WP_015058546	DNA topoisomerase I [Streptococcus agalactiae].	24.86	519	318	19	7	504	25	492	1e-18	100
rs:WP_044413633	DNA topoisomerase I [Thioalkalimicrobium microaerophilum].	25.62	523	302	22	7	504	5	465	1e-18	100
rs:WP_045737421	DNA topoisomerase I [Xanthomonas sp. MUS 060].	24.68	539	318	18	7	505	6	496	1e-18	100
tr:Q64CK3_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.19	554	343	20	75	595	54	563	1e-18	100
rs:WP_035505356	MULTISPECIES: DNA topoisomerase I [Halobacillus].	28.03	421	255	14	112	505	82	481	1e-18	100
rs:WP_041584091	DNA topoisomerase I [Bacteroides salanitronis].	22.90	559	356	20	4	536	1	510	1e-18	99.8
tr:A0A0E2RVE6_STRTR	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EWM61844.1};	24.47	523	314	18	7	504	32	498	1e-18	100
rs:WP_039044872	DNA topoisomerase I [Plesiomonas shigelloides].	24.26	544	322	19	7	505	6	504	1e-18	100
rs:WP_011681086	DNA topoisomerase I [Streptococcus thermophilus].	24.47	523	314	18	7	504	34	500	1e-18	100
rs:WP_046206438	DNA topoisomerase I [Streptococcus thermophilus].	24.47	523	314	18	7	504	34	500	1e-18	100
rs:WP_011227156	DNA topoisomerase I [Streptococcus thermophilus].	24.47	523	314	18	7	504	34	500	1e-18	100
rs:WP_003668086	DNA topoisomerase I [Lactobacillus reuteri].	24.76	525	314	19	7	504	25	495	1e-18	100
rs:WP_024809418	DNA topoisomerase I [Oceanicola sp. HL-35].	26.14	547	309	24	4	510	1	492	1e-18	100
rs:WP_041018111	DNA topoisomerase I [Criblamydia sequanensis].	25.37	540	321	21	7	505	6	504	1e-18	100
rs:WP_039564478	DNA topoisomerase I, partial [Xanthomonas campestris].	23.82	592	349	20	7	563	6	530	1e-18	100
rs:WP_000246615	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	1e-18	100
rs:WP_036010230	DNA topoisomerase I [Leptolyngbya sp. JSC-1].	26.30	441	259	16	103	505	78	490	1e-18	100
rs:WP_009880163	DNA topoisomerase III [Bacillus anthracis].	29.50	278	169	10	295	554	2	270	1e-18	97.8
rs:WP_035169862	DNA topoisomerase I [Lactobacillus reuteri].	24.76	525	314	19	7	504	25	495	1e-18	100
rs:WP_011752551	DNA topoisomerase [Thermofilum pendens].	24.96	557	341	17	1	530	1	507	1e-18	100
tr:C8PI89_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.51	443	276	13	89	505	59	473	1e-18	100
rs:WP_003167051	DNA topoisomerase I [Brevundimonas diminuta].	25.82	546	314	22	7	510	4	500	1e-18	100
tr:A6DJX4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.51	559	317	21	1	510	1	503	1e-18	100
tr:W7B1H7_9LIST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.57	224	150	4	329	544	10	231	1e-18	98.2
rs:WP_005224424	DNA topoisomerase I [Marichromatium purpuratum].	24.30	539	325	20	4	505	1	493	1e-18	100
rs:WP_023211986	DNA topoisomerase I subunit omega [Salmonella enterica].	26.35	463	293	16	64	505	63	498	1e-18	100
rs:WP_007184766	DNA topoisomerase I [Hydrocarboniphaga effusa].	25.23	543	312	19	7	505	6	498	1e-18	100
rs:WP_002880197	DNA topoisomerase I [Lactobacillus delbrueckii].	25.34	521	316	18	7	504	36	506	1e-18	100
rs:WP_010503653	DNA topoisomerase I subunit omega [Gluconobacter frateurii].	25.68	549	313	25	7	510	5	503	1e-18	100
rs:WP_041125153	DNA topoisomerase I, partial [Sulfurovum sp. FS06-10].	25.91	521	313	21	7	504	5	475	1e-18	100
rs:WP_020976736	DNA topoisomerase I, omega protein I [Salmonella enterica].	25.97	539	313	21	7	505	6	498	1e-18	100
rs:WP_014565034	DNA topoisomerase I [Lactobacillus delbrueckii].	25.14	521	317	18	7	504	39	509	1e-18	100
rs:WP_009872013	DNA topoisomerase I [Chlamydia trachomatis].	25.95	555	324	22	46	563	30	534	1e-18	100
rs:WP_036443188	DNA topoisomerase I [Mycoplasma hyosynoviae].	25.06	443	281	16	84	504	56	469	1e-18	99.8
rs:WP_035157700	DNA topoisomerase I [Lactobacillus reuteri].	24.76	525	314	19	7	504	25	495	1e-18	100
sp:TOP1_AERPE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.36	552	345	20	7	539	1	504	1e-18	100
rs:WP_002273112	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	1e-18	100
rs:WP_042225960	DNA topoisomerase I, partial [Porphyromonas cansulci].	24.32	366	243	12	262	602	28	384	1e-18	99.4
tr:R0MTD2_STRMT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.69	436	266	15	97	504	26	431	1e-18	99.8
tr:K8ECN4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.57	628	369	23	3	593	2	555	1e-18	100
rs:WP_020744912	DNA topoisomerase I subunit omega [Alteromonas macleodii].	26.45	431	276	14	93	505	99	506	1e-18	100
rs:WP_041136416	DNA topoisomerase I [Sulfurovum sp. AS07-7].	26.74	430	268	18	99	504	68	474	1e-18	100
tr:L8JJT3_9BACT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ELR68513.1};	29.44	231	142	6	8	233	5	219	1e-18	96.3
rs:WP_009092353	DNA topoisomerase I subunit omega, partial [Elizabethkingia anophelis].	32.46	228	137	5	4	231	1	211	1e-18	96.3
rs:WP_002838175	DNA topoisomerase I [Finegoldia magna].	24.48	527	327	17	1	505	1	478	2e-18	100
rs:WP_014085710	DNA topoisomerase I [Pseudogulbenkiania sp. NH8B].	24.72	538	327	18	7	510	6	499	2e-18	100
rs:WP_014103479	DNA topoisomerase I [Micavibrio aeruginosavorus].	26.59	549	303	24	1	505	1	493	2e-18	100
tr:G5JN01_STRCG	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.10	527	312	19	7	504	46	513	2e-18	100
rs:WP_023409680	DNA topoisomerase I [uncultured Thiohalocapsa sp. PB-PSB1].	25.64	546	311	22	7	505	4	501	2e-18	100
rs:WP_021828753	MULTISPECIES: DNA topoisomerase I [Bacteria].	25.23	543	314	23	7	505	6	500	2e-18	100
rs:WP_039926969	DNA topoisomerase I [Leptospira vanthielii].	23.78	576	343	22	39	584	7	516	2e-18	99.8
rs:WP_040804917	DNA topoisomerase I [Streptococcus criceti].	24.10	527	312	19	7	504	33	500	2e-18	100
rs:WP_012971263	DNA topoisomerase I [Allochromatium vinosum].	24.67	535	322	19	7	505	4	493	2e-18	100
rs:WP_029237111	DNA topoisomerase I [Streptococcus sobrinus].	24.57	521	317	19	7	504	33	500	2e-18	100
rs:WP_005010707	DNA topoisomerase I [Nitrospina gracilis].	24.09	552	311	22	7	510	6	497	2e-18	100
rs:WP_027827406	DNA topoisomerase I [Lactobacillus harbinensis].	25.04	607	348	24	7	581	6	537	2e-18	99.8
gp:HE983624_851	DNA topoisomerase I [Streptococcus pneumoniae SPNA45]	25.46	436	267	15	97	504	26	431	2e-18	99.8
sp:TOP1_SALTI	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.33	537	319	20	7	505	6	498	2e-18	100
rs:WP_002275215	DNA topoisomerase I [Streptococcus mutans].	24.71	522	315	20	7	504	24	491	2e-18	99.8
rs:WP_011264301	topoisomerase I [Salmonella enterica].	25.33	537	319	20	7	505	6	498	2e-18	100
tr:D1Y390_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.69	541	301	23	5	505	73	552	2e-18	100
tr:B9YAX6_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.88	627	368	27	1	596	1	555	2e-18	99.8
rs:WP_034933050	DNA topoisomerase I [Erwinia mallotivora].	25.81	461	288	16	69	505	68	498	2e-18	100
rs:WP_023423913	DNA topoisomerase I, archaeal [uncultured Acidilobus sp. MG].	25.00	564	336	23	6	541	2	506	2e-18	99.8
rs:WP_013010160	DNA topoisomerase I [Denitrovibrio acetiphilus].	25.75	532	308	21	7	505	6	483	2e-18	100
rs:WP_018075375	DNA topoisomerase I [Novosphingobium nitrogenifigens].	25.93	540	293	25	7	505	4	477	2e-18	100
rs:WP_027333036	DNA topoisomerase I [Mycoplasma gallinarum].	24.16	538	333	19	7	517	5	494	2e-18	99.8
rs:WP_015468187	DNA topoisomerase I [Micavibrio aeruginosavorus].	26.79	545	307	25	1	505	1	493	2e-18	100
rs:WP_017124206	DNA topoisomerase I [Pseudomonas gingeri].	23.68	604	372	20	41	600	3	561	2e-18	99.8
rs:WP_010093441	DNA topoisomerase I [Ornithinibacillus scapharcae].	23.76	526	323	19	7	504	6	481	2e-18	99.8
rs:WP_023246917	DNA topoisomerase I subunit omega [Salmonella enterica].	24.95	537	321	19	7	505	6	498	2e-18	100
rs:WP_002285804	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	2e-18	99.8
rs:WP_008949746	topoisomerase I [Alishewanella jeotgali].	24.86	539	316	19	7	505	6	495	2e-18	100
tr:F8I2K1_SULAT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.53	539	293	28	10	504	2	481	2e-18	99.8
rs:WP_013013879	DNA topoisomerase I [Meiothermus ruber].	23.92	623	355	26	1	579	1	548	2e-18	100
rs:WP_021091637	DNA topoisomerase I [Campylobacter concisus].	26.47	442	275	15	89	505	59	475	2e-18	99.8
rs:WP_019251607	DNA topoisomerase I [Lactobacillus reuteri].	24.76	525	314	19	7	504	25	495	2e-18	99.8
rs:WP_022233276	DNA topoisomerase III [Bacteroides sp. CAG:443].	22.16	564	354	22	4	536	1	510	2e-18	99.4
tr:F1ZA60_9SPHN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.48	433	250	19	107	505	70	472	2e-18	100
rs:WP_029052307	DNA topoisomerase I [Sporosarcina ureae].	27.38	431	253	18	107	504	77	480	2e-18	99.8
rs:WP_046993897	DNA topoisomerase I [Arcobacter butzleri].	24.34	645	361	25	7	605	5	568	2e-18	100
rs:WP_023243911	DNA topoisomerase 1 [Salmonella enterica].	25.33	537	319	20	7	505	6	498	2e-18	100
rs:WP_008089323	DNA topoisomerase I [Streptococcus ictaluri].	23.90	523	318	17	7	504	30	497	2e-18	99.8
rs:WP_026317155	DNA topoisomerase I [Ahrensia kielensis].	26.50	566	298	26	4	510	1	507	2e-18	100
rs:WP_036311140	DNA topoisomerase I [Methylophaga thiooxydans].	24.02	533	327	18	7	505	6	494	2e-18	99.8
rs:WP_022096555	DNA topoisomerase [Streptococcus thermophilus CAG:236].	24.28	523	315	18	7	504	34	500	2e-18	99.8
rs:WP_002950606	DNA topoisomerase I [Streptococcus thermophilus].	24.28	523	315	18	7	504	34	500	2e-18	99.8
rs:WP_000513592	topoisomerase I [Salmonella enterica].	25.79	539	314	21	7	505	6	498	2e-18	100
tr:I0GNA0_SELRL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.33	612	346	27	5	581	19	554	2e-18	99.8
rs:WP_046093242	DNA topoisomerase I [Salmonella enterica].	25.33	537	319	20	7	505	6	498	2e-18	100
rs:WP_000513591	DNA topoisomerase 1 [Salmonella enterica].	25.33	537	319	20	7	505	6	498	2e-18	100
rs:WP_039518565	DNA topoisomerase I [Xanthomonas arboricola].	23.99	592	348	20	7	563	6	530	2e-18	100
rs:WP_036124760	DNA topoisomerase I [Lysinibacillus sphaericus].	26.51	430	255	16	109	504	79	481	2e-18	99.8
rs:WP_046902757	DNA topoisomerase I [Altererythrobacter atlanticus].	26.33	547	298	24	7	510	4	488	2e-18	100
rs:WP_003717034	DNA topoisomerase I [Lactobacillus vaginalis].	25.62	523	312	21	7	504	27	497	2e-18	99.8
rs:WP_006119337	topoisomerase I [Pantoea stewartii].	26.59	455	292	15	69	505	68	498	2e-18	100
rs:WP_023138314	DNA topoisomerase I [Salmonella enterica].	25.33	537	319	20	7	505	6	498	2e-18	100
rs:WP_028967690	DNA topoisomerase I [Sphingomonas phyllosphaerae].	26.96	523	306	25	7	505	4	474	2e-18	100
rs:WP_003048468	DNA topoisomerase I [Streptococcus canis].	24.18	521	319	18	7	504	29	496	2e-18	99.8
tr:D1J990_9ARCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.73	552	348	19	75	595	54	563	2e-18	99.8
rs:WP_001633920	DNA topoisomerase 1 [Salmonella enterica].	25.79	539	314	21	7	505	6	498	2e-18	100
rs:WP_023206147	DNA topoisomerase I subunit omega [Salmonella enterica].	25.33	537	319	20	7	505	6	498	2e-18	100
gp:CP006631_2795	DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Newport str.]	25.79	539	314	21	7	505	8	500	2e-18	100
rs:WP_028129147	DNA topoisomerase I [Selenomonas sp. AE3005].	24.84	628	353	29	7	595	36	583	2e-18	99.8
rs:WP_034276053	DNA topoisomerase III, partial [Bacillus sp. 171095_106].	33.77	151	97	2	383	530	2	152	2e-18	97.1
rs:WP_023207743	DNA topoisomerase 1 [Salmonella enterica].	25.33	537	319	20	7	505	6	498	2e-18	100
rs:WP_019468457	DNA topoisomerase I [Staphylococcus sp. AL1].	25.05	527	313	19	7	505	6	478	2e-18	99.8
rs:WP_038803946	DNA topoisomerase I, partial [Salmonella enterica].	25.33	537	319	20	7	505	6	498	2e-18	100
rs:WP_024955483	DNA topoisomerase I [Sulfurospirillum arcachonense].	23.82	529	315	20	7	505	5	475	2e-18	99.8
gpu:CP007584_1792	DNA topoisomerase 1 [Salmonella enterica subsp. enterica serovar Anatum str.]	25.33	537	319	20	7	505	8	500	2e-18	100
tr:A0A0E2Q2V1_STRTR	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:ETW89632.1};	24.47	523	314	18	7	504	34	500	2e-18	99.8
rs:WP_040205630	DNA topoisomerase III, partial [Klebsiella pneumoniae].	31.62	234	136	5	332	543	1	232	2e-18	98.2
rs:WP_035547526	DNA topoisomerase I, partial [Halobacillus sp. BBL2006].	25.71	529	310	18	7	505	6	481	2e-18	99.4
gpu:CP009695_24	DNA topoisomerase family protein [Bacillus anthracis]	29.50	278	169	10	295	554	2	270	2e-18	98.2
rs:WP_019321618	DNA topoisomerase I [Streptococcus mutans].	24.38	521	318	19	7	504	24	491	2e-18	99.8
tr:T4BJJ7_PEPDI	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	23.63	512	334	16	65	562	107	575	2e-18	99.8
rs:WP_042272078	DNA topoisomerase I [Clostridium sp. 01].	27.00	526	307	20	5	504	4	478	2e-18	99.8
rs:WP_003670294	topoisomerase I [Moraxella catarrhalis].	24.76	529	326	20	88	596	104	580	2e-18	99.8
rs:WP_045728597	DNA topoisomerase I [Xanthomonas sp. GPE 39].	24.68	539	318	18	7	505	6	496	2e-18	99.8
rs:WP_044144925	DNA topoisomerase I, partial [Salmonella enterica].	25.79	539	314	21	7	505	6	498	2e-18	99.8
rs:WP_013833968	DNA topoisomerase I [Novosphingobium sp. PP1Y].	25.99	531	302	22	7	505	4	475	2e-18	99.8
rs:WP_015158856	DNA topoisomerase I [Chamaesiphon minutus].	25.05	459	290	17	91	516	65	502	2e-18	99.8
rs:WP_002300224	DNA topoisomerase I [Streptococcus mutans].	25.90	525	305	22	7	504	24	491	2e-18	99.8
rs:WP_037563553	DNA topoisomerase I [Streptococcus agalactiae].	24.43	524	314	18	7	504	25	492	2e-18	99.8
rs:WP_021872352	DNA topoisomerase [Clostridium sp. CAG:1193].	25.38	524	313	21	7	506	5	474	2e-18	99.4
rs:WP_026893862	DNA topoisomerase I [Clostridiisalibacter paucivorans].	25.05	555	328	19	7	539	6	494	2e-18	99.8
rs:WP_023926537	hypothetical protein [Prevotella nigrescens].	26.93	349	210	11	5	333	3	326	2e-18	96.7
rs:WP_033500581	DNA topoisomerase III, partial [Bifidobacterium kashiwanohense].	27.39	303	184	9	7	301	4	278	2e-18	96.3
rs:WP_033741827	DNA topoisomerase I [Pantoea stewartii].	26.59	455	292	15	69	505	68	498	2e-18	99.8
rs:WP_002952806	DNA topoisomerase 1 [Salmonella enterica].	25.33	537	319	20	7	505	6	498	2e-18	99.8
rs:WP_012917334	DNA topoisomerase I [Xanthomonas albilineans].	24.68	539	318	18	7	505	6	496	2e-18	99.8
rs:WP_013459042	DNA topoisomerase I [Sulfuricurvum kujiense].	24.71	433	288	10	92	505	61	474	2e-18	99.8
rs:WP_017650225	DNA topoisomerase I [Streptococcus agalactiae].	24.86	519	318	19	7	504	25	492	2e-18	99.8
gp:CP007804_1672	DNA topoisomerase I [Salmonella enterica subsp. enterica serovar Typhimurium]	25.79	539	314	21	7	505	8	500	2e-18	99.8
rs:WP_019318811	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	2e-18	99.8
rs:WP_043520017	DNA topoisomerase, partial [Acidobacteriaceae bacterium TAA166].	24.02	587	316	23	7	510	6	545	2e-18	99.8
rs:WP_024352735	DNA topoisomerase I [Brevundimonas naejangsanensis].	25.05	543	322	20	7	510	4	500	2e-18	99.8
rs:WP_019517463	DNA topoisomerase I [Sphingomonas sp. Mn802worker].	26.73	520	311	22	7	505	4	474	2e-18	99.8
rs:WP_012660909	DNA topoisomerase I [Campylobacter lari].	24.36	427	288	11	89	500	59	465	2e-18	99.4
rs:WP_042092685	hypothetical protein, partial [Escherichia coli].	29.89	271	151	8	304	544	52	313	2e-18	97.1
rs:WP_045490136	DNA topoisomerase I [Candidatus Liberibacter asiaticus].	24.36	546	313	22	4	504	1	491	2e-18	99.8
rs:WP_023240746	DNA topoisomerase 1 [Salmonella enterica].	25.33	537	319	20	7	505	6	498	2e-18	99.8
rs:WP_040099963	DNA topoisomerase I, partial [Geoalkalibacter ferrihydriticus].	25.14	537	315	19	7	505	6	493	2e-18	99.8
rs:WP_000246612	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	2e-18	99.4
rs:WP_045770649	DNA topoisomerase I [Xanthomonas albilineans].	24.68	539	318	18	7	505	6	496	2e-18	99.8
rs:WP_042394310	DNA topoisomerase I [Escherichia vulneris].	24.72	534	326	19	7	505	6	498	2e-18	99.8
rs:WP_025005757	DNA topoisomerase I [Lactobacillus gallinarum].	24.24	524	320	17	7	505	19	490	2e-18	99.4
rs:WP_041914241	DNA topoisomerase I [Selenomonas ruminantium].	25.37	611	345	27	5	580	26	560	2e-18	99.8
rs:WP_006787029	DNA topoisomerase I [Thiorhodospira sibirica].	23.56	539	322	16	7	505	6	494	2e-18	99.8
rs:WP_039413639	DNA topoisomerase I [Xanthomonas campestris].	23.82	592	349	20	7	563	6	530	2e-18	99.8
rs:XP_006596164	PREDICTED: uncharacterized protein LOC100778913 [Glycine max].	25.24	523	312	18	36	504	274	771	2e-18	100
rs:WP_000246614	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	2e-18	99.4
rs:WP_040611837	DNA topoisomerase I [Roseomonas cervicalis].	25.28	542	313	23	7	505	5	497	2e-18	99.8
rs:WP_019836908	topoisomerase I [Acinetobacter sp. MDS7A].	25.74	439	276	14	88	505	108	517	2e-18	99.8
rs:WP_019413034	DNA topoisomerase I [Paenisporosarcina sp. TG20].	26.59	425	254	16	112	504	82	480	2e-18	99.4
rs:WP_045766368	DNA topoisomerase I [Xanthomonas albilineans].	24.68	539	318	18	7	505	6	496	2e-18	99.8
rs:WP_012778525	DNA topoisomerase I [Candidatus Liberibacter asiaticus].	24.54	546	312	23	4	504	1	491	2e-18	99.8
rs:WP_022305902	DNA topoisomerase [Roseburia sp. CAG:380].	25.27	364	213	15	289	604	34	386	2e-18	97.4
rs:WP_000513590	topoisomerase I [Salmonella enterica].	25.33	537	319	20	7	505	6	498	2e-18	99.8
rs:WP_002382349	DNA topoisomerase I, partial [Enterococcus faecalis].	24.33	526	319	18	7	504	7	481	2e-18	99.4
rs:WP_002265839	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	2e-18	99.4
rs:WP_007622319	DNA topoisomerase I [Glaciecola arctica].	25.29	435	276	15	93	505	99	506	2e-18	99.8
rs:WP_023168632	DNA topoisomerase I subunit omega [Salmonella enterica].	25.33	537	319	20	7	505	6	498	2e-18	99.8
tr:V6Z0Z2_STRAG	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.43	524	314	18	7	504	22	489	2e-18	99.4
rs:WP_036441042	DNA topoisomerase I [Mycoplasma hyosynoviae].	25.45	448	273	17	84	504	56	469	2e-18	99.4
rs:WP_006738721	DNA topoisomerase I [Streptococcus urinalis].	24.05	524	316	18	7	504	29	496	2e-18	99.4
tr:A0A0C9PQX4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.09	534	313	21	7	505	9	490	2e-18	99.4
rs:WP_003003886	DNA topoisomerase I [Sphingobacterium spiritivorum].	26.07	445	269	12	89	505	59	471	2e-18	99.4
rs:WP_000513589	topoisomerase I [Salmonella enterica].	24.95	537	321	19	7	505	6	498	2e-18	99.8
rs:WP_002282013	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	2e-18	99.4
rs:WP_008226122	DNA topoisomerase I [Roseobacter sp. GAI101].	25.27	546	315	22	4	510	1	492	2e-18	99.8
rs:WP_022798377	DNA topoisomerase I [Thermus islandicus].	25.65	538	312	25	5	505	14	500	2e-18	99.8
rs:WP_018250549	DNA topoisomerase I [Sphingomonas melonis].	27.60	529	295	24	7	505	4	474	2e-18	99.8
rs:WP_019805905	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	2e-18	99.4
rs:WP_014868857	DNA topoisomerase I [Wolbachia endosymbiont of Onchocerca ochengi].	25.09	550	311	22	7	510	4	498	2e-18	99.8
rs:WP_043153070	DNA topoisomerase I [Pseudomonas aeruginosa].	25.84	476	287	17	99	553	76	506	2e-18	99.4
rs:WP_011452790	DNA topoisomerase I [Ehrlichia chaffeensis].	26.42	545	318	20	4	510	1	500	2e-18	99.4
rs:WP_020843081	DNA topoisomerase I [Lactobacillus reuteri].	24.57	525	315	20	7	504	25	495	3e-18	99.4
rs:WP_031935128	DNA topoisomerase I [Candidatus Liberibacter asiaticus].	24.39	537	318	21	7	504	10	497	3e-18	99.4
rs:WP_028118478	DNA topoisomerase I [Facklamia sourekii].	25.76	528	317	19	1	505	1	476	3e-18	99.4
rs:WP_041122387	DNA topoisomerase I [Jeotgalibacillus alimentarius].	25.14	533	307	20	7	504	6	481	3e-18	99.4
rs:WP_025902260	DNA topoisomerase I, partial [Tatumella sp. UCD-D_suzukii].	26.25	320	206	9	201	505	13	317	3e-18	98.6
sp:TOP1P_XYLFA	RecName: Full=DNA topoisomerase I, plasmid {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.00	508	307	16	73	555	45	503	3e-18	99.4
rs:WP_016994084	DNA topoisomerase I [Lysinibacillus boronitolerans].	26.73	434	249	16	109	504	79	481	3e-18	99.4
rs:WP_027466409	DNA topoisomerase I [Curtobacterium sp. UNCCL17].	24.46	560	320	21	7	504	8	526	3e-18	99.8
rs:WP_035439122	DNA topoisomerase III, partial [Bacillus sp. RP1137].	33.77	151	97	2	383	530	2	152	3e-18	96.7
rs:WP_000246601	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	3e-18	99.4
rs:WP_008336353	DNA topoisomerase I [Sulfurimonas gotlandica].	23.40	517	333	15	7	505	4	475	3e-18	99.4
rs:WP_010376861	DNA topoisomerase I [Xanthomonas campestris].	23.65	592	350	20	7	563	6	530	3e-18	99.4
rs:WP_039643387	DNA topoisomerase I [Geobacter sp. GSS01].	25.70	533	314	19	7	505	6	490	3e-18	99.4
rs:WP_016396514	DNA topoisomerase I [Lactobacillus delbrueckii].	26.91	431	271	14	97	504	10	419	3e-18	99.0
rs:WP_017977323	DNA topoisomerase I [Sphingomonas melonis].	27.60	529	295	24	7	505	4	474	3e-18	99.4
rs:WP_017115144	DNA topoisomerase I [Xanthomonas vasicola].	23.65	592	350	20	7	563	6	530	3e-18	99.4
rs:WP_003083749	DNA topoisomerase I [Streptococcus porcinus].	23.85	524	317	17	7	504	29	496	3e-18	99.4
rs:WP_029140909	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	3e-18	99.4
rs:WP_000513581	DNA topoisomerase I subunit omega [Salmonella enterica].	25.33	537	319	20	7	505	6	498	3e-18	99.4
tr:A0A090SLL0_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL27763.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL27763.1};	27.39	303	205	7	4	301	1	293	3e-18	96.3
rs:WP_003020611	MULTISPECIES: topoisomerase I [Citrobacter].	24.67	535	325	19	7	505	6	498	3e-18	99.4
tr:S4NKE1_9PORP	SubName: Full=DNA topoisomerase III, Bacteroidales-type {ECO:0000313|EMBL:GAD07880.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAD07880.1};	24.56	342	226	11	284	602	2	334	3e-18	97.8
tr:C9M7U6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.48	457	287	15	81	505	26	465	3e-18	99.0
rs:WP_008954815	DNA topoisomerase I [Pseudogulbenkiania ferrooxidans].	24.72	538	327	18	7	510	6	499	3e-18	99.4
gpu:CP010867_998	DNA topoisomerase 1 [Streptococcus agalactiae]	24.66	519	319	19	7	504	28	495	3e-18	99.4
rs:WP_002351232	toprim domain protein, partial [Enterococcus faecium].	35.14	185	106	7	5	182	3	180	3e-18	94.0
rs:WP_012111753	DNA topoisomerase I [Parvibaculum lavamentivorans].	24.73	562	307	26	4	510	1	501	3e-18	99.4
tr:D5RQA4_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.28	542	313	23	7	505	18	510	3e-18	99.4
rs:WP_002275904	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	3e-18	99.4
rs:WP_000246605	DNA topoisomerase I [Streptococcus agalactiae].	24.86	519	318	19	7	504	25	492	3e-18	99.4
tr:K1SYX7_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC52511.1}; Flags: Fragment;	29.53	254	154	7	107	359	17	246	3e-18	95.5
rs:WP_019314697	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	3e-18	99.4
rs:WP_003164641	DNA topoisomerase I [Brevundimonas diminuta].	25.27	546	317	21	7	510	4	500	3e-18	99.4
rs:WP_033158878	DNA topoisomerase I [Methylomonas sp. LW13].	25.84	592	343	21	3	562	2	529	3e-18	99.4
rs:WP_041981298	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	3e-18	99.4
rs:WP_000246613	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	3e-18	99.4
rs:WP_010370069	DNA topoisomerase I [Xanthomonas vasicola].	23.65	592	350	20	7	563	6	530	3e-18	99.4
rs:WP_039865010	DNA topoisomerase I [Holdemania filiformis].	24.96	621	363	27	7	596	5	553	3e-18	99.0
rs:WP_006821526	DNA topoisomerase I [Corynebacterium casei].	24.77	553	328	22	2	505	5	518	3e-18	99.8
rs:WP_025386990	DNA topoisomerase I [Corynebacterium casei].	24.77	553	328	22	2	505	5	518	3e-18	99.8
rs:WP_017647390	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	3e-18	99.0
rs:WP_033047184	hypothetical protein, partial [Clostridium botulinum].	30.04	263	148	9	158	417	36	265	3e-18	96.3
rs:WP_015898448	DNA topoisomerase [Acidobacterium capsulatum].	23.87	666	369	28	3	607	2	590	3e-18	99.4
rs:WP_044710918	DNA topoisomerase I, partial [Citrobacter freundii].	24.77	537	322	19	7	505	6	498	3e-18	99.0
rs:WP_002272153	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	3e-18	99.0
rs:WP_024783829	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	3e-18	99.0
rs:WP_014334730	DNA topoisomerase I [Streptococcus infantarius].	24.66	519	319	18	7	504	31	498	3e-18	99.0
rs:WP_019773825	DNA topoisomerase I, partial [Streptococcus sobrinus].	25.35	434	271	13	97	504	13	419	3e-18	99.0
gpu:CP009695_23	DNA topoisomerase family protein [Bacillus anthracis]	32.00	225	128	9	5	218	3	213	3e-18	94.4
tr:H8YX88_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	554	320	21	4	505	11	513	3e-18	99.4
rs:WP_024785984	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	3e-18	99.0
rs:WP_024891862	DNA topoisomerase I [Luteimonas huabeiensis].	24.86	539	317	18	7	505	6	496	3e-18	99.4
rs:WP_015606150	DNA topoisomerase I [Salmonella enterica].	25.33	537	319	20	7	505	6	498	3e-18	99.4
tr:A0A0A8I1J1_CAMLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.18	409	271	11	107	500	77	465	3e-18	99.0
rs:WP_019802704	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	3e-18	99.0
rs:WP_002286698	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	3e-18	99.0
tr:A0A075H5S9_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.74	577	377	19	7	567	24	553	3e-18	99.0
rs:WP_033161459	DNA topoisomerase I [Mycoplasma collis].	24.28	519	324	17	7	504	5	475	3e-18	99.0
rs:WP_033973126	DNA topoisomerase I [Pseudomonas aeruginosa].	25.45	495	296	18	86	553	58	506	3e-18	99.0
rs:WP_013758112	DNA topoisomerase I [Treponema brennaborense].	25.38	528	308	20	7	504	22	493	3e-18	99.0
rs:WP_008238576	DNA topoisomerase I [Pedobacter sp. BAL39].	24.94	449	264	15	89	504	59	467	3e-18	99.4
rs:WP_042057047	DNA topoisomerase I, partial [Acidomonas methanolica].	24.91	546	315	24	1	505	1	492	3e-18	99.4
tr:A0A0A8HWB1_CAMLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.18	409	271	11	107	500	77	465	3e-18	99.0
rs:WP_002287969	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	3e-18	99.0
rs:WP_039617287	DNA topoisomerase I [Campylobacter lari].	25.18	409	271	11	107	500	78	466	3e-18	99.0
rs:WP_007256547	DNA topoisomerase I [Oceanicola granulosus].	24.82	556	307	21	4	510	1	494	3e-18	99.4
rs:WP_000246609	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	3e-18	99.0
rs:WP_017121437	DNA topoisomerase I [Xanthomonas vasicola].	23.65	592	350	20	7	563	6	530	3e-18	99.4
tr:A0A023D3N6_ACIMT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.91	546	315	24	1	505	1	492	3e-18	99.4
rs:WP_002282653	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	3e-18	99.0
rs:WP_040855033	DNA topoisomerase I [Thiorhodovibrio sp. 970].	23.65	554	320	21	4	505	1	503	3e-18	99.4
rs:WP_012274955	hypothetical protein [Collimonas fungivorans].	23.00	526	329	15	43	543	25	499	3e-18	99.4
rs:WP_012521875	DNA topoisomerase I [Phenylobacterium zucineum].	25.68	553	309	26	4	510	1	497	3e-18	99.4
rs:WP_019320014	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	3e-18	99.0
rs:WP_000246610	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	3e-18	99.0
rs:WP_039696903	DNA topoisomerase I [Streptococcus equinus].	24.62	520	318	17	7	504	31	498	3e-18	99.0
rs:WP_044170579	DNA topoisomerase I [Ehrlichia chaffeensis].	26.64	548	313	22	4	510	1	500	3e-18	99.4
tr:V8LW74_STRTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.28	523	315	18	7	504	34	500	3e-18	99.0
tr:K1RY66_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EKC50268.1}; Flags: Fragment;	25.76	528	301	21	7	498	5	477	3e-18	98.2
rs:WP_041657431	DNA topoisomerase I, partial [Marinobacter hydrocarbonoclasticus].	26.65	529	295	22	7	506	6	470	3e-18	98.6
rs:WP_010713378	DNA topoisomerase 1 [Enterococcus faecalis].	24.33	526	319	18	7	504	7	481	3e-18	99.0
rs:WP_014608256	DNA topoisomerase I [Streptococcus thermophilus].	24.28	523	315	18	7	504	34	500	3e-18	99.0
rs:WP_020966639	DNA topoisomerase I [Chlamydia trachomatis].	25.77	555	325	22	46	563	30	534	3e-18	99.4
rs:WP_002262866	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	3e-18	99.0
rs:WP_001649179	DNA topoisomerase I [Salmonella enterica].	25.33	537	319	20	7	505	6	498	3e-18	99.4
rs:WP_014727521	DNA topoisomerase I [Streptococcus thermophilus].	24.28	523	315	18	7	504	34	500	3e-18	99.0
rs:WP_014306395	DNA topoisomerase I [Corynebacterium diphtheriae].	25.92	463	283	17	86	505	75	520	3e-18	99.4
rs:WP_041816684	DNA topoisomerase III, partial [Bacillus megaterium].	33.77	151	97	2	383	530	2	152	3e-18	96.3
rs:WP_039625170	DNA topoisomerase I [Campylobacter lari].	25.18	409	271	11	107	500	78	466	3e-18	99.0
rs:WP_000246611	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	3e-18	99.0
rs:WP_000246600	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	3e-18	99.0
rs:WP_005987997	DNA topoisomerase I [Xanthomonas vesicatoria].	23.82	592	349	20	7	563	6	530	3e-18	99.4
rs:WP_023101571	DNA topoisomerase I [Pseudomonas aeruginosa].	25.45	495	296	18	86	553	58	506	3e-18	99.0
rs:WP_023234051	DNA topoisomerase I subunit omega [Salmonella enterica].	25.33	537	319	20	7	505	6	498	3e-18	99.4
rs:WP_023213660	DNA topoisomerase I subunit omega [Salmonella enterica].	25.33	537	319	20	7	505	6	498	3e-18	99.4
tr:A0A099Q3J4_9XANT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	592	350	20	7	563	6	530	3e-18	99.4
rs:WP_011062924	DNA topoisomerase I [Pseudomonas protegens].	25.23	432	274	16	97	504	75	481	3e-18	99.0
rs:WP_005682871	DNA topoisomerase III [Bacteroides caccae].	22.18	568	372	21	4	550	1	519	3e-18	98.6
rs:WP_019532523	DNA topoisomerase I [Paenibacillus ginsengihumi].	24.81	528	321	19	5	504	4	483	3e-18	99.0
rs:WP_029236761	DNA topoisomerase I [Streptococcus sobrinus].	24.38	521	318	19	7	504	33	500	3e-18	99.0
rs:WP_017644456	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	3e-18	99.0
rs:WP_004229276	DNA topoisomerase I [Lysinibacillus fusiformis].	26.73	434	249	16	109	504	79	481	3e-18	99.0
rs:WP_007788928	DNA topoisomerase I [Peptostreptococcus stomatis].	23.70	633	378	26	7	607	6	565	3e-18	99.0
tr:J6CY98_PASMD	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJS91690.1}; Flags: Fragment;	36.42	162	90	5	377	530	1	157	3e-18	93.2
rs:WP_012308892	DNA topoisomerase I [Candidatus Korarchaeum cryptofilum].	25.29	601	366	27	5	579	3	546	3e-18	99.0
rs:WP_034130508	DNA topoisomerase I [Peptococcaceae bacterium BICA1-8].	23.38	633	381	24	5	606	4	563	3e-18	99.0
rs:WP_045443510	DNA topoisomerase I [Citrobacter sp. S-77].	24.86	535	324	19	7	505	6	498	3e-18	99.4
rs:WP_040030611	DNA topoisomerase I [Staphylococcus cohnii].	25.05	527	313	19	7	505	6	478	3e-18	99.0
tr:A0A078L6H7_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.53	591	351	23	7	564	6	534	3e-18	99.4
rs:WP_038893010	DNA topoisomerase III, partial [Vibrio campbellii].	30.39	204	125	3	361	549	5	206	3e-18	94.7
rs:WP_038391634	DNA topoisomerase I [Salmonella bongori].	25.05	535	323	19	7	505	6	498	3e-18	99.4
rs:WP_019641165	DNA topoisomerase I [Thioalkalivibrio sp. ALSr1].	24.86	535	320	19	7	505	6	494	3e-18	99.4
tr:K2EQ64_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.52	447	260	19	91	510	60	469	3e-18	99.0
rs:WP_002283154	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	3e-18	99.0
rs:WP_017646538	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	3e-18	99.0
rs:WP_047207279	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	3e-18	99.0
rs:WP_002642410	DNA topoisomerase I [Simonsiella muelleri].	27.44	441	261	14	103	505	73	492	3e-18	99.0
rs:WP_021246507	DNA topoisomerase I [Sphingobium baderi].	26.00	523	311	20	7	505	4	474	3e-18	99.4
rs:WP_002305945	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	3e-18	99.0
tr:W7VEV5_STRTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.28	523	315	18	7	504	34	500	3e-18	99.0
rs:WP_019557205	DNA topoisomerase I [Thiomicrospira arctica].	24.76	513	318	19	7	504	5	464	3e-18	99.0
rs:WP_033502000	DNA topoisomerase III, partial [Bifidobacterium kashiwanohense].	28.88	232	152	4	7	236	4	224	3e-18	95.5
rs:WP_000513582	topoisomerase I [Salmonella bongori].	25.05	535	323	19	7	505	6	498	3e-18	99.0
rs:WP_034161568	DNA topoisomerase I [Sphingomonas sp. ERG5].	26.25	522	311	22	7	505	4	474	3e-18	99.0
rs:WP_013458656	DNA topoisomerase I [Oceanithermus profundus].	23.74	636	378	23	1	599	1	566	3e-18	99.0
rs:WP_032131555	DNA topoisomerase I [Weeksella sp. FF8].	25.72	521	302	20	7	504	6	464	3e-18	99.0
rs:WP_045792501	DNA topoisomerase I [Acinetobacter brisouii].	26.42	439	273	13	88	505	109	518	3e-18	99.0
rs:WP_042957237	DNA topoisomerase, partial [Enterococcus faecium].	29.43	265	165	7	315	563	17	275	4e-18	96.7
rs:WP_019792460	DNA topoisomerase I, partial [Streptococcus sobrinus].	25.23	436	269	13	97	504	51	457	4e-18	98.6
rs:WP_045750540	DNA topoisomerase I [Methylophilaceae bacterium MMS-10A-171].	25.66	534	314	20	7	504	5	491	4e-18	99.0
rs:WP_043114455	DNA topoisomerase I [Solimonas soli].	25.25	598	338	24	7	562	6	536	4e-18	99.0
rs:WP_028716244	DNA topoisomerase I [Paracoccus sp. J39].	25.19	532	315	18	4	505	1	479	4e-18	99.0
rs:WP_046219671	DNA topoisomerase I [Photobacterium halotolerans].	24.22	545	320	19	7	505	6	503	4e-18	99.0
rs:WP_028713422	DNA topoisomerase I [Paracoccus sp. J55].	25.19	532	315	18	4	505	1	479	4e-18	99.0
rs:WP_047210202	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	4e-18	99.0
rs:WP_022513709	DNA topoisomerase [Dialister sp. CAG:588].	24.72	534	310	21	7	504	38	515	4e-18	99.0
rs:WP_021678025	DNA topoisomerase, partial [Porphyromonas gingivalis].	27.96	304	179	14	162	455	5	278	4e-18	95.5
rs:WP_009872811	DNA topoisomerase I [Chlamydia trachomatis].	25.77	555	325	22	46	563	30	534	4e-18	99.0
rs:WP_037325674	DNA topoisomerase I [Anaerovibrio sp. RM50].	25.46	538	308	24	107	599	72	561	4e-18	99.0
rs:WP_002352070	DNA topoisomerase, partial [Enterococcus faecium].	29.43	265	165	7	315	563	10	268	4e-18	96.3
rs:WP_002267968	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	4e-18	98.6
tr:T0CMX4_CLOSO	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EPZ55487.1};	30.47	233	147	5	7	237	4	223	4e-18	95.5
rs:WP_002809370	DNA topoisomerase I [Xanthomonas fragariae].	23.82	592	349	20	7	563	6	530	4e-18	99.0
rs:WP_018589680	DNA topoisomerase I [Terrisporobacter glycolicus].	25.28	621	348	28	5	589	4	544	4e-18	98.6
rs:WP_002350833	DNA topoisomerase, partial [Enterococcus faecium].	29.43	265	165	7	315	563	2	260	4e-18	96.3
rs:WP_038805147	DNA topoisomerase I, partial [Salmonella enterica].	25.33	537	319	20	7	505	6	498	4e-18	99.0
rs:WP_000513595	DNA topoisomerase 1 [Salmonella enterica].	25.60	539	315	21	7	505	6	498	4e-18	99.0
rs:WP_002309563	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	4e-18	98.6
rs:WP_018509290	DNA topoisomerase I [Thiobacillus thioparus].	26.29	426	267	16	107	505	75	480	4e-18	99.0
rs:WP_016506808	DNA topoisomerase 1 [Salmonella enterica].	25.14	537	320	20	7	505	6	498	4e-18	99.0
rs:WP_023178015	MULTISPECIES: DNA topoisomerase I [Carnobacterium].	24.43	569	347	20	1	540	1	515	4e-18	98.6
tr:W1MU77_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.45	495	296	18	86	553	10	458	4e-18	98.6
rs:WP_039732367	DNA topoisomerase I [Komagataeibacter intermedius].	25.41	551	314	25	7	510	5	505	4e-18	99.0
rs:WP_005182090	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	23.64	533	332	17	7	505	25	516	4e-18	99.0
rs:WP_045284154	DNA topoisomerase I [Enterobacter sp. 35032].	24.51	559	332	19	5	545	3	489	4e-18	98.6
rs:WP_002281097	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	4e-18	98.6
rs:WP_021334812	DNA topoisomerase I subunit omega, partial [Corynebacterium diphtheriae].	25.70	463	284	16	86	505	75	520	4e-18	98.6
tr:A3IRZ5_9CHRO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.12	430	264	13	107	504	105	508	4e-18	98.6
tr:A0A0A3W6Y3_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.27	471	282	17	56	505	73	494	4e-18	99.0
rs:WP_003092737	DNA topoisomerase I [Streptococcus vestibularis].	24.43	524	313	19	7	504	30	496	4e-18	98.6
rs:WP_010237231	DNA topoisomerase I [Citromicrobium bathyomarinum].	25.27	546	304	24	7	510	4	487	4e-18	99.0
rs:WP_034281770	DNA topoisomerase I [Bacillus safensis].	25.61	531	316	20	112	607	82	568	4e-18	98.6
rs:WP_009807374	DNA topoisomerase I [Oceanicola batsensis].	26.40	534	308	22	4	505	1	481	4e-18	99.0
rs:WP_008990855	DNA topoisomerase I [Galbibacter marinus].	25.58	516	308	19	7	504	6	463	4e-18	99.0
gpu:CP009498_962	DNA topoisomerase 1 [Candidatus Endomicrobium sp. Rsa215]	24.95	529	317	18	7	505	6	484	4e-18	98.6
rs:WP_027304177	DNA topoisomerase I [Campylobacter upsaliensis].	23.86	528	316	18	7	505	6	476	4e-18	98.6
rs:WP_033973543	DNA topoisomerase I [Pseudomonas aeruginosa].	25.35	497	294	19	86	553	58	506	4e-18	98.6
rs:WP_033077867	DNA topoisomerase I [Thalassotalea sp. ND16A].	25.00	544	321	18	7	505	6	507	4e-18	99.0
rs:WP_000513596	topoisomerase I [Salmonella enterica].	25.14	537	320	20	7	505	6	498	4e-18	99.0
rs:WP_015158955	DNA topoisomerase I [Chamaesiphon minutus].	24.62	459	292	17	91	516	65	502	4e-18	98.6
rs:WP_031674614	DNA topoisomerase I [Listeria monocytogenes].	26.78	422	263	14	109	504	79	480	4e-18	98.6
rs:WP_024783479	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	4e-18	98.6
rs:WP_006010019	DNA topoisomerase I [Ehrlichia chaffeensis].	26.42	545	318	20	4	510	1	500	4e-18	99.0
tr:R2W343_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOI37178.1};	30.32	221	138	7	5	218	3	214	4e-18	94.7
rs:WP_042838739	DNA topoisomerase I [Xanthomonas citri].	23.95	593	347	21	7	563	6	530	4e-18	99.0
rs:WP_045796399	DNA topoisomerase I [Acinetobacter indicus].	23.83	533	331	17	7	505	25	516	4e-18	99.0
rs:WP_000246604	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	4e-18	98.6
tr:A0A0D7M0I9_CITFR	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJC12167.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJC12167.1}; Flags: Fragment;	24.77	537	322	19	7	505	6	498	4e-18	98.6
rs:WP_039284392	DNA topoisomerase I [Novosphingobium malaysiense].	26.18	531	301	22	7	505	4	475	4e-18	99.0
rs:WP_024785252	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	4e-18	98.6
rs:WP_034585104	DNA topoisomerase I [Acinetobacter sp. HR7].	25.27	471	282	17	56	505	97	518	4e-18	99.0
rs:WP_046135880	DNA topoisomerase I [Devosia limi].	27.54	472	263	20	80	505	46	484	4e-18	99.0
rs:WP_010785477	DNA topoisomerase 1 [Enterococcus faecalis].	24.33	526	319	18	7	504	7	481	4e-18	98.6
gpu:CP011805_1000	DNA topoisomerase 1 [Altererythrobacter marensis]	26.79	545	296	25	7	510	4	486	4e-18	99.0
rs:WP_018365968	DNA topoisomerase I [Streptococcus didelphis].	23.94	518	324	16	7	504	34	501	4e-18	98.6
rs:WP_002357484	MULTISPECIES: DNA topoisomerase I [Enterococcus].	24.33	526	319	18	7	504	7	481	4e-18	98.6
rs:WP_016616347	DNA topoisomerase I [Enterococcus faecalis].	24.33	526	319	18	7	504	7	481	4e-18	98.6
rs:WP_035221505	DNA topoisomerase, partial [Acidobacteriaceae bacterium KBS 83].	22.68	626	368	24	3	579	2	560	4e-18	98.6
tr:J0V077_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.71	522	321	17	7	505	12	484	4e-18	98.6
rs:WP_014366395	DNA topoisomerase I [Corynebacterium pseudotuberculosis].	25.70	463	284	16	86	505	75	520	4e-18	99.0
rs:WP_019396332	DNA topoisomerase I [Pseudomonas aeruginosa].	25.25	495	297	18	86	553	58	506	4e-18	98.2
rs:WP_034455431	DNA topoisomerase I [Buttiauxella agrestis].	25.43	464	296	15	64	505	63	498	4e-18	99.0
rs:WP_010514841	DNA topoisomerase I [Komagataeibacter oboediens].	25.41	551	314	25	7	510	5	505	4e-18	99.0
rs:WP_040849999	DNA topoisomerase I [Thiovulum sp. ES].	24.71	522	321	17	7	505	5	477	4e-18	98.6
rs:WP_025209884	DNA topoisomerase I [Hippea sp. KM1].	23.83	621	371	21	7	598	4	551	5e-18	98.6
rs:WP_016505322	DNA topoisomerase I [Salmonella enterica].	25.14	537	320	20	7	505	6	498	5e-18	98.6
rs:WP_036634295	DNA topoisomerase I, partial [Paenirhodobacter enshiensis].	24.76	529	319	20	4	505	1	477	5e-18	98.6
tr:E3YPQ4_9LIST	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.73	419	261	14	112	504	82	480	5e-18	98.6
tr:C9KMX8_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.72	615	350	28	7	580	32	574	5e-18	98.6
rs:WP_044662359	DNA topoisomerase I [Sphingobium sp. YBL2].	25.81	523	312	20	7	505	4	474	5e-18	98.6
rs:WP_010666274	DNA topoisomerase I [Acetobacter aceti].	25.09	554	311	27	7	510	5	504	5e-18	98.6
rs:WP_042434696	DNA topoisomerase [Senegalimassilia anaerobia].	23.84	516	338	16	65	562	107	585	5e-18	98.6
rs:WP_020208865	hypothetical protein [Gilvimarinus chinensis].	25.24	511	318	22	91	580	58	525	5e-18	98.2
rs:WP_002380330	DNA topoisomerase I [Enterococcus faecalis].	24.33	526	319	18	7	504	7	481	5e-18	98.6
rs:WP_025986837	DNA topoisomerase I [Pseudomonas aeruginosa].	25.55	497	293	20	86	553	58	506	5e-18	98.2
rs:WP_000513594	topoisomerase I [Salmonella enterica].	25.14	537	320	20	7	505	6	498	5e-18	98.6
rs:WP_021064912	hypothetical protein [Agrococcus pavilionensis].	24.13	543	331	19	7	505	6	511	5e-18	98.6
rs:WP_032802204	DNA topoisomerase I [Corynebacterium pseudotuberculosis].	25.70	463	284	16	86	505	75	520	5e-18	99.0
rs:WP_034216741	MULTISPECIES: DNA topoisomerase I [Arcobacter].	25.79	539	301	21	7	504	5	485	5e-18	98.6
rs:WP_010784903	DNA topoisomerase 1 [Enterococcus faecalis].	24.33	526	319	18	7	504	7	481	5e-18	98.2
rs:WP_002276719	DNA topoisomerase I [Streptococcus mutans].	24.81	524	312	21	7	504	24	491	5e-18	98.6
rs:WP_016508253	DNA topoisomerase I [Exiguobacterium sp. S17].	24.33	637	376	24	7	607	6	572	5e-18	98.2
rs:WP_025977129	DNA topoisomerase I [Brevundimonas naejangsanensis].	25.27	546	317	22	7	510	4	500	5e-18	98.6
rs:WP_002264284	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	5e-18	98.2
rs:WP_013784485	topoisomerase I [Alteromonas sp. SN2].	27.00	426	269	15	99	505	104	506	5e-18	98.6
rs:WP_035152627	DNA topoisomerase I [Lactobacillus reuteri].	24.57	525	315	19	7	504	25	495	5e-18	98.2
rs:WP_027191454	DNA topoisomerase I [Desulfovibrio putealis].	24.82	544	324	20	63	567	19	516	5e-18	98.2
rs:WP_023098077	DNA topoisomerase I [Pseudomonas aeruginosa].	25.45	495	296	18	86	553	58	506	5e-18	98.2
rs:WP_018718076	DNA topoisomerase I [Arhodomonas aquaeolei].	24.68	539	317	20	7	505	6	495	5e-18	98.6
rs:WP_046140197	DNA topoisomerase I [Devosia insulae].	26.51	547	294	25	4	505	1	484	5e-18	98.6
rs:WP_039503944	DNA topoisomerase I [Salmonella enterica].	25.23	535	322	19	7	505	6	498	5e-18	98.6
rs:WP_037599980	DNA topoisomerase I [Streptococcus sp. ACS2].	24.90	526	308	20	7	504	34	500	5e-18	98.2
rs:WP_002278553	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	5e-18	98.2
rs:WP_007351674	DNA topoisomerase I [Marinobacter sp. ELB17].	24.91	578	315	25	7	551	6	497	5e-18	98.2
rs:WP_032272977	DNA topoisomerase III, partial [Escherichia coli].	32.39	176	104	1	379	539	7	182	5e-18	95.9
rs:WP_029889569	hypothetical protein, partial [Polycyclovorans algicola].	24.07	536	321	18	7	504	6	493	5e-18	98.6
rs:WP_002381874	DNA topoisomerase I [Enterococcus faecalis].	24.33	526	319	18	7	504	7	481	5e-18	98.2
rs:WP_044275446	DNA topoisomerase I [Pseudomonas fluorescens].	25.29	514	318	16	43	539	30	494	5e-18	98.2
rs:WP_002997891	DNA topoisomerase I [Streptococcus downei].	23.66	524	318	17	7	504	33	500	5e-18	98.2
rs:WP_045926121	DNA topoisomerase I [Bacillus siamensis].	26.25	522	308	19	112	599	82	560	5e-18	98.2
rs:WP_016936131	DNA topoisomerase I [Bacillus siamensis].	26.25	522	308	19	112	599	82	560	5e-18	98.2
rs:WP_016830088	DNA topoisomerase I [Corynebacterium diphtheriae].	25.70	463	284	16	86	505	75	520	5e-18	98.6
rs:WP_014318578	DNA topoisomerase I [Corynebacterium diphtheriae].	25.70	463	284	16	86	505	75	520	5e-18	98.6
rs:WP_036292883	DNA topoisomerase I [Methylobacter whittenburyi].	25.13	589	342	20	7	562	6	528	5e-18	98.6
rs:WP_023026804	DNA topoisomerase I [Streptococcus sp. I-G2].	25.52	525	306	23	7	504	17	483	5e-18	98.2
rs:WP_014317501	DNA topoisomerase I [Corynebacterium diphtheriae].	25.92	463	283	17	86	505	75	520	5e-18	98.6
rs:WP_025315708	DNA topoisomerase I [Gilliamella apicola].	24.86	535	323	21	7	505	6	497	5e-18	98.6
rs:WP_045808600	DNA topoisomerase I [Candidatus Neoehrlichia lotoris].	26.40	534	313	20	4	504	1	487	5e-18	98.6
rs:WP_009304728	MULTISPECIES: DNA topoisomerase [Eggerthella].	23.93	514	330	17	65	562	107	575	5e-18	98.6
tr:V8CFY5_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.11	442	282	14	89	505	59	476	5e-18	98.6
rs:WP_003723893	DNA topoisomerase I, partial [Listeria monocytogenes].	27.14	409	255	14	112	498	82	469	5e-18	97.1
rs:WP_035055313	DNA topoisomerase I, partial [Desulfuromonas sp. TF].	25.09	534	316	20	7	505	6	490	5e-18	98.2
tr:B1SFB3_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.66	519	319	18	7	504	49	516	5e-18	98.2
rs:WP_020650998	DNA topoisomerase I [Solimonas variicoloris].	25.00	604	332	26	7	562	6	536	5e-18	98.6
rs:WP_002290910	DNA topoisomerase I [Streptococcus mutans].	25.57	524	308	21	7	504	24	491	5e-18	98.2
rs:WP_035096835	DNA topoisomerase I [Devosia sp. LC5].	26.37	546	296	24	4	505	1	484	5e-18	98.6
rs:WP_039584828	DNA topoisomerase III, partial [Xanthomonas axonopodis].	29.65	226	148	5	8	233	5	219	5e-18	94.0
rs:WP_029238067	DNA topoisomerase I [Streptococcus sobrinus].	23.66	524	318	17	7	504	33	500	5e-18	98.2
rs:WP_020482931	DNA topoisomerase I [Methylomonas sp. MK1].	25.59	594	342	21	3	562	2	529	5e-18	98.2
rs:WP_006317433	DNA topoisomerase I [Caldisalinibacter kiritimatiensis].	24.04	624	368	24	7	598	6	555	5e-18	98.2
rs:WP_024365688	DNA topoisomerase I [Arthrobacter sp. TB 26].	25.54	556	312	21	7	505	12	522	5e-18	98.6
rs:WP_011927903	DNA topoisomerase I [Dichelobacter nodosus].	24.68	539	319	19	1	505	1	486	5e-18	98.6
tr:A8EWX5_ARCB4	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.22	563	323	22	89	605	32	542	5e-18	98.2
rs:WP_000246603	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	5e-18	98.2
rs:WP_010829429	DNA topoisomerase 1 [Enterococcus faecalis].	24.33	526	319	18	7	504	7	481	5e-18	98.2
rs:WP_040286872	DNA topoisomerase I [Sporosarcina koreensis].	25.62	527	312	19	7	504	6	481	5e-18	98.2
rs:WP_046701437	DNA topoisomerase I [Moraxella bovoculi].	24.94	437	281	15	88	505	106	514	5e-18	98.6
rs:WP_016119355	DNA topoisomerase 1, partial [Bacillus cereus].	26.10	341	222	9	5	337	4	322	5e-18	95.5
rs:WP_020949217	DNA topoisomerase I [Paracoccus aminophilus].	25.98	535	307	24	4	505	1	479	5e-18	98.6
rs:WP_036890994	DNA topoisomerase I, partial [Prevotella corporis].	25.65	347	217	9	5	333	3	326	6e-18	95.5
rs:WP_017173006	DNA topoisomerase I, partial [Xanthomonas axonopodis].	23.65	592	350	20	7	563	6	530	6e-18	98.6
rs:WP_038452705	DNA topoisomerase I [Campylobacter iguaniorum].	25.74	439	282	13	89	505	59	475	6e-18	98.2
rs:WP_034578557	DNA topoisomerase I, partial [Helicobacter canis].	25.11	442	282	14	89	505	59	476	6e-18	98.2
rs:WP_043878370	DNA topoisomerase I [Streptococcus infantarius].	24.66	519	319	18	7	504	31	498	6e-18	98.2
rs:WP_041041004	DNA topoisomerase I [Tolypothrix campylonemoides].	24.67	450	289	14	84	504	59	487	6e-18	98.2
rs:WP_029325907	MULTISPECIES: DNA topoisomerase I [Bacillus].	26.60	421	259	14	112	504	82	480	6e-18	98.2
rs:WP_026601896	DNA topoisomerase I [Methylomonas sp. 11b].	25.59	594	342	21	3	562	2	529	6e-18	98.2
rs:WP_004231665	DNA topoisomerase I [Streptococcus equinus].	24.62	520	318	17	7	504	31	498	6e-18	98.2
rs:WP_000513598	topoisomerase I [Salmonella enterica].	25.33	537	319	20	7	505	6	498	6e-18	98.6
rs:WP_044056878	DNA topoisomerase I [Alteromonas australica].	26.22	431	277	14	93	505	99	506	6e-18	98.6
rs:WP_002407054	DNA topoisomerase I [Enterococcus faecalis].	24.33	526	319	18	7	504	7	481	6e-18	98.2
rs:WP_003853868	MULTISPECIES: topoisomerase I [Pantoea].	26.04	457	292	16	69	505	77	507	6e-18	98.6
rs:WP_029775883	DNA topoisomerase I, partial [delta proteobacterium JGI 0000059-K16].	25.62	441	278	14	94	505	75	494	6e-18	98.2
rs:WP_005036280	DNA topoisomerase I [Holophaga foetida].	25.87	549	308	22	7	505	5	504	6e-18	98.2
rs:WP_038892912	DNA topoisomerase III, partial [Vibrio campbellii].	29.21	202	130	2	361	549	5	206	6e-18	94.0
rs:WP_007635410	DNA topoisomerase I [Glaciecola psychrophila].	24.83	435	278	15	93	505	99	506	6e-18	98.6
rs:WP_027222752	DNA topoisomerase I [Legionella pneumophila].	24.91	542	311	16	7	505	6	494	6e-18	98.2
rs:WP_022846308	DNA topoisomerase I [Desulfurobacterium sp. TC5-1].	23.99	567	344	18	7	553	9	508	6e-18	98.2
rs:WP_035799481	DNA topoisomerase I [Cyanothece sp. CCY0110].	25.12	430	264	13	107	504	85	488	6e-18	98.2
rs:WP_002308087	topoisomerase I [Enterococcus faecium].	28.71	209	139	5	43	248	12	213	6e-18	94.0
rs:WP_032136609	DNA topoisomerase I [Kingella sp. Sch538].	26.83	451	266	15	103	510	73	502	6e-18	98.2
rs:WP_003136185	DNA topoisomerase I [Lactococcus garvieae].	26.84	421	261	15	107	504	106	502	6e-18	98.2
rs:WP_002287487	DNA topoisomerase I [Streptococcus mutans].	25.71	525	306	22	7	504	24	491	6e-18	98.2
rs:WP_019316381	DNA topoisomerase I [Streptococcus mutans].	24.81	524	312	21	7	504	24	491	6e-18	98.2
rs:WP_040636070	DNA topoisomerase I [Mitsuokella multacida].	24.55	615	351	28	7	580	39	581	6e-18	98.2
rs:WP_037590747	DNA topoisomerase I [Streptococcus hyovaginalis].	24.24	524	315	18	7	504	25	492	6e-18	98.2
tr:A1U7T2_MARHV	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:ABM21051.1}; EC=5.99.1.2 {ECO:0000313|EMBL:ABM21051.1};	26.93	531	291	23	7	506	6	470	6e-18	98.2
rs:WP_045797922	DNA topoisomerase I [Streptococcus equinus].	24.28	519	321	17	7	504	31	498	6e-18	98.2
rs:WP_007970275	DNA topoisomerase I [Xanthomonas fuscans].	23.65	592	350	20	7	563	6	530	6e-18	98.2
rs:WP_025547373	DNA topoisomerase I [Sphingobium sp. KK22].	25.81	523	312	20	7	505	4	474	6e-18	98.2
rs:WP_014302829	DNA topoisomerase I [Corynebacterium diphtheriae].	25.92	463	283	17	86	505	75	520	6e-18	98.6
rs:WP_013297943	DNA topoisomerase I [Thermoanaerobacterium thermosaccharolyticum].	23.84	625	372	22	7	598	6	559	6e-18	98.2
rs:WP_037019380	DNA topoisomerase I [Pseudomonas lutea].	23.27	507	328	16	38	515	25	499	6e-18	98.2
rs:WP_014316296	DNA topoisomerase I [Corynebacterium diphtheriae].	25.92	463	283	17	86	505	75	520	6e-18	98.6
rs:WP_008572030	DNA topoisomerase I [Xanthomonas perforans].	23.65	592	350	20	7	563	6	530	6e-18	98.2
rs:WP_044447104	DNA topoisomerase I [Alteromonas australica].	26.22	431	277	14	93	505	99	506	6e-18	98.2
rs:WP_029820479	DNA topoisomerase I [Xanthomonas alfalfae].	23.65	592	350	20	7	563	6	530	6e-18	98.2
rs:WP_015311654	DNA topoisomerase I [Thermoanaerobacterium thermosaccharolyticum].	23.36	625	375	20	7	598	6	559	6e-18	98.2
rs:WP_020083156	topoisomerase I [gamma proteobacterium SCGC AAA160-D02].	24.60	435	291	12	88	505	98	512	6e-18	98.2
rs:WP_003850467	DNA topoisomerase I [Corynebacterium diphtheriae].	25.92	463	283	17	86	505	75	520	6e-18	98.6
rs:WP_012032416	DNA topoisomerase I [Pelotomaculum thermopropionicum].	24.61	577	340	22	3	553	2	509	6e-18	98.2
tr:I2HR12_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.60	421	259	14	112	504	84	482	6e-18	98.2
rs:WP_028991696	DNA topoisomerase I [Thermoanaerobacter thermocopriae].	24.65	568	339	21	7	553	6	505	6e-18	98.2
rs:WP_014309924	DNA topoisomerase I [Corynebacterium diphtheriae].	25.92	463	283	17	86	505	75	520	6e-18	98.6
rs:WP_006701213	DNA topoisomerase I [Facklamia ignava].	25.33	525	311	20	7	504	6	476	6e-18	97.8
rs:WP_021067110	MULTISPECIES: DNA topoisomerase I [Exiguobacterium].	24.18	637	377	22	7	607	6	572	6e-18	97.8
rs:WP_029508370	DNA topoisomerase I [Lactobacillus suebicus].	25.76	524	310	22	7	504	24	494	6e-18	98.2
rs:WP_020033631	hypothetical protein [Oceanospirillales bacterium SCGC AAA298-N10].	24.91	534	325	18	7	505	6	498	6e-18	98.2
rs:WP_032631661	DNA topoisomerase III, partial [Pseudomonas syringae].	31.46	178	106	3	324	485	2	179	6e-18	92.8
rs:WP_045107952	DNA topoisomerase I [Pseudomonas sp. HMSC05H02].	25.35	497	294	20	86	553	58	506	6e-18	97.8
rs:WP_023093022	DNA topoisomerase I [Pseudomonas aeruginosa].	25.45	495	296	18	86	553	58	506	6e-18	97.8
rs:WP_021335436	DNA topoisomerase I subunit omega [Corynebacterium diphtheriae].	25.92	463	283	17	86	505	75	520	6e-18	98.2
rs:WP_011348788	MULTISPECIES: DNA topoisomerase I [Xanthomonas].	23.65	592	350	20	7	563	6	530	6e-18	98.2
rs:WP_038048163	DNA topoisomerase I [Thermus caliditerrae].	24.73	546	314	22	3	505	24	515	6e-18	98.2
rs:WP_039690742	DNA topoisomerase I [Streptococcus equinus].	24.42	520	319	17	7	504	31	498	7e-18	97.8
tr:S4TL54_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.03	595	350	21	7	564	6	535	7e-18	98.2
rs:WP_038020773	DNA topoisomerase I [Tatumella morbirosei].	26.39	451	260	17	88	505	87	498	7e-18	98.2
rs:WP_022246783	DNA topoisomerase [Clostridium sp. CAG:306].	24.64	625	366	24	7	597	19	572	7e-18	98.2
rs:WP_024301152	DNA topoisomerase I [Pseudogulbenkiania sp. MAI-1].	24.72	538	327	18	7	510	6	499	7e-18	98.2
rs:WP_028447198	DNA topoisomerase I [Chitinimonas koreensis].	26.59	440	270	14	107	510	77	499	7e-18	98.2
gp:CP003149_4723	DNA topoisomerase I [Pseudomonas aeruginosa DK2]	25.45	495	296	18	86	553	10	458	7e-18	97.8
rs:XP_009367981	PREDICTED: uncharacterized protein LOC103957527 isoform X2 [Pyrus x bretschneideri].	26.19	527	302	20	36	505	371	867	7e-18	98.6
rs:WP_019312541	DNA topoisomerase I [Streptococcus mutans].	25.52	525	307	22	7	504	24	491	7e-18	97.8
rs:WP_027232501	DNA topoisomerase I [Phyllobacterium sp. UNC302MFCol5.2].	26.39	557	300	27	7	510	4	503	7e-18	98.2
rs:WP_046169030	DNA topoisomerase I [Devosia psychrophila].	27.02	470	268	18	80	505	46	484	7e-18	98.2
rs:WP_014307889	DNA topoisomerase I [Corynebacterium diphtheriae].	25.92	463	283	17	86	505	75	520	7e-18	98.2
rs:WP_035122695	DNA topoisomerase I [Corynebacterium freneyi].	26.37	474	278	19	86	505	75	531	7e-18	98.2
rs:WP_023944543	DNA topoisomerase 1 [Gluconobacter frateurii].	25.50	549	314	25	7	510	5	503	7e-18	98.2
rs:WP_014533317	DNA topoisomerase I [Staphylococcus lugdunensis].	27.34	428	251	16	107	504	77	474	7e-18	97.8
rs:WP_003840713	MULTISPECIES: DNA topoisomerase I subunit omega [Enterobacteriaceae].	24.67	535	325	19	7	505	6	498	7e-18	98.2
rs:WP_041111666	DNA topoisomerase I [Gluconobacter oxydans].	25.95	555	304	27	7	510	5	503	7e-18	98.2
rs:WP_011252816	DNA topoisomerase I [Gluconobacter oxydans].	25.95	555	304	27	7	510	5	503	7e-18	98.2
rs:WP_022090080	DNA topoisomerase [Clostridium sp. CAG:492].	24.39	537	328	19	7	512	6	495	7e-18	97.8
rs:WP_010751238	DNA topoisomerase 1 [Enterococcus villorum].	24.52	526	318	18	7	504	7	481	7e-18	97.8
rs:WP_012535748	DNA topoisomerase I [Acidithiobacillus ferrooxidans].	23.11	541	322	17	7	505	6	494	7e-18	98.2
rs:WP_043895033	DNA topoisomerase I [Streptococcus lutetiensis].	24.57	525	312	17	7	504	31	498	7e-18	97.8
rs:WP_013944621	DNA topoisomerase I [Simkania negevensis].	24.39	619	361	25	5	580	8	562	7e-18	98.2
rs:WP_034773800	DNA topoisomerase I [Idiomarina salinarum].	24.05	528	344	19	7	505	6	505	7e-18	98.2
rs:WP_032017180	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	7e-18	98.2
rs:WP_019995290	DNA topoisomerase I [Aureimonas ureilytica].	26.93	557	294	27	4	505	1	499	7e-18	98.2
rs:WP_037441137	DNA topoisomerase I [Sphingobacterium antarcticum].	25.45	448	263	15	89	504	59	467	7e-18	98.2
rs:WP_041433679	DNA topoisomerase I [Thermus sp. CCB_US3_UF1].	25.32	541	309	23	7	505	2	489	7e-18	98.2
rs:WP_020303003	DNA topoisomerase I [Pseudomonas sp. CF150].	23.88	582	371	18	43	603	30	560	7e-18	97.8
rs:WP_033918373	DNA topoisomerase I [Listeria monocytogenes].	27.14	420	258	15	112	504	82	480	7e-18	97.8
rs:WP_026375035	DNA topoisomerase I [Aestuariibacter salexigens].	25.32	541	322	21	7	505	6	506	7e-18	98.2
rs:WP_034051068	DNA topoisomerase I [Pseudomonas aeruginosa].	25.35	497	294	19	86	553	58	506	7e-18	97.8
rs:WP_002351757	DNA topoisomerase I [Streptococcus mutans].	25.52	525	307	22	7	504	24	491	7e-18	97.8
rs:WP_013150348	DNA topoisomerase I [Thermoanaerobacter mathranii].	24.65	568	339	21	7	553	6	505	7e-18	97.8
rs:WP_006418410	DNA topoisomerase I [Eremococcus coleocola].	24.05	528	325	17	1	505	1	475	8e-18	97.8
rs:WP_007123236	DNA topoisomerase I [Lactobacillus antri].	25.05	523	315	22	7	504	31	501	8e-18	97.8
rs:WP_011146662	topoisomerase I [Photorhabdus luminescens].	24.84	455	298	15	69	504	68	497	8e-18	98.2
rs:WP_017157050	DNA topoisomerase I [Xanthomonas axonopodis].	23.65	592	350	20	7	563	6	530	8e-18	97.8
rs:WP_038268119	DNA topoisomerase I [[Clostridium] litorale].	26.01	569	327	24	7	553	6	502	8e-18	97.8
rs:WP_007891355	DNA topoisomerase I [Streptococcus pseudoporcinus].	23.76	526	315	18	7	504	29	496	8e-18	97.8
rs:WP_018935946	DNA topoisomerase I [Thioalkalivibrio sp. ALJ24].	24.86	535	320	19	7	505	6	494	8e-18	98.2
rs:WP_042538864	DNA topoisomerase I [Curtobacterium flaccumfaciens].	24.29	560	321	21	7	504	8	526	8e-18	98.2
rs:WP_004899308	DNA topoisomerase I [Acinetobacter brisouii].	25.85	441	273	15	88	505	109	518	8e-18	97.8
rs:WP_033657820	hypothetical protein [Enterococcus faecium].	34.59	185	107	7	5	182	3	180	8e-18	93.2
rs:WP_005776835	MULTISPECIES: DNA topoisomerase III [Bacteroides].	22.30	565	352	20	4	536	1	510	8e-18	97.4
rs:WP_017666344	DNA topoisomerase I [Porphyrobacter sp. AAP82].	26.70	543	298	27	7	510	4	485	8e-18	97.8
rs:WP_042199154	DNA topoisomerase I [Paenibacillus sp. G4].	24.72	530	317	20	5	504	4	481	8e-18	97.8
rs:WP_046208644	DNA topoisomerase I [Staphylococcus cohnii].	24.81	524	318	18	7	505	6	478	8e-18	97.8
rs:WP_014091221	DNA topoisomerase I [Xanthomonas alfalfae].	23.65	592	350	20	7	563	6	530	8e-18	97.8
rs:WP_028491545	DNA topoisomerase I [Thioalkalivibrio sp. ALE19].	24.82	544	309	20	7	505	6	494	8e-18	97.8
rs:WP_044841803	DNA topoisomerase I [Thalassomonas viridans].	24.86	543	320	20	7	505	6	504	8e-18	97.8
rs:WP_022134546	DNA topoisomerase [Clostridium sp. CAG:594].	25.77	520	310	22	7	504	6	471	8e-18	97.4
tr:S5QX37_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.57	525	312	17	7	504	49	516	8e-18	97.8
rs:WP_004352838	DNA topoisomerase I [Pseudomonas aeruginosa].	25.55	497	293	20	86	553	58	506	8e-18	97.4
rs:WP_019714400	DNA topoisomerase I [Bacillus subtilis].	27.25	422	255	15	112	504	82	480	8e-18	97.8
rs:WP_033985421	DNA topoisomerase I [Pseudomonas aeruginosa].	25.45	495	296	19	86	553	58	506	8e-18	97.4
rs:WP_014522099	DNA topoisomerase I [Corynebacterium pseudotuberculosis].	25.70	463	284	16	86	505	75	520	8e-18	98.2
rs:WP_042177548	DNA topoisomerase I [Paenibacillus sp. FSL R7-0331].	24.72	530	317	20	5	504	4	481	8e-18	97.8
rs:WP_034777177	DNA topoisomerase I [Exiguobacterium mexicanum].	24.33	637	376	22	7	607	6	572	8e-18	97.8
rs:WP_019591561	DNA topoisomerase I [Thioalkalivibrio sp. ALE20].	24.82	544	309	20	7	505	6	494	8e-18	97.8
rs:WP_031875871	DNA topoisomerase III, partial [Staphylococcus aureus].	31.34	201	131	5	364	559	7	205	8e-18	95.5
rs:WP_046155113	DNA topoisomerase I [Citrobacter freundii].	24.67	535	325	19	7	505	6	498	8e-18	97.8
rs:WP_038320683	DNA topoisomerase I [Kingella kingae].	27.05	451	265	15	103	510	73	502	8e-18	97.8
rs:WP_009987542	DNA topoisomerase III [Ruminococcus flavefaciens].	27.60	337	212	10	4	322	1	323	8e-18	94.7
gpu:CP010889_230	DNA topoisomerase 1 [Corynebacterium pseudotuberculosis]	25.70	463	284	16	86	505	65	510	8e-18	97.8
rs:WP_032048758	DNA topoisomerase I [Acinetobacter baumannii].	23.75	539	324	18	7	505	25	516	8e-18	97.8
rs:WP_014799952	DNA topoisomerase I [Corynebacterium pseudotuberculosis].	25.70	463	284	16	86	505	75	520	9e-18	97.8
rs:WP_036883715	DNA topoisomerase I [Porphyromonas gingivicanis].	24.64	552	326	19	7	530	8	497	9e-18	97.8
rs:WP_019805740	DNA topoisomerase I [Streptococcus mutans].	25.52	525	307	22	7	504	24	491	9e-18	97.4
rs:WP_034820062	DNA topoisomerase I [Idiomarina sp. 28-8].	22.99	522	357	15	7	505	6	505	9e-18	97.8
gpu:CP011474_232	DNA topoisomerase I [Corynebacterium pseudotuberculosis]	25.70	463	284	16	86	505	117	562	9e-18	98.2
rs:WP_000352443	DNA topoisomerase I, partial [Bacillus thuringiensis].	27.04	355	225	9	271	606	45	384	9e-18	97.4
rs:XP_001620777	hypothetical protein NEMVEDRAFT_v1g222712, partial [Nematostella vectensis].	27.85	237	158	6	8	244	5	228	9e-18	93.6
tr:A0A0A8H7G6_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.43	409	270	11	107	500	77	465	9e-18	97.4
rs:WP_014558563	DNA topoisomerase I [Corynebacterium pseudotuberculosis].	25.70	463	284	16	86	505	75	520	9e-18	97.8
tr:M2PJT3_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EMD15854.1};	25.44	287	182	10	7	291	4	260	9e-18	94.0
tr:D9QDZ9_CORP2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.70	463	284	16	86	505	81	526	9e-18	97.8
rs:WP_010714635	hypothetical protein, partial [Enterococcus faecalis].	34.59	185	108	7	5	182	3	181	9e-18	92.8
rs:WP_026443392	DNA topoisomerase [Acidobacterium sp. PMMR2].	23.40	624	362	25	3	579	2	556	9e-18	97.8
rs:WP_044617686	DNA topoisomerase I [Gynuella sunshinyii].	23.20	543	335	16	7	505	6	510	9e-18	97.8
rs:WP_017888707	hypothetical protein [Curtobacterium flaccumfaciens].	24.29	560	321	21	7	504	8	526	9e-18	97.8
rs:WP_024562448	MULTISPECIES: DNA topoisomerase I [Cronobacter].	24.30	535	327	18	7	505	6	498	9e-18	97.8
rs:WP_043801410	DNA topoisomerase I [Arenimonas malthae].	23.79	597	353	22	7	568	6	535	9e-18	97.8
rs:WP_026799764	DNA topoisomerase I [Pontibacillus halophilus].	25.96	443	275	15	93	505	63	482	9e-18	97.4
gp:CP003385_222	DNA topoisomerase I [Corynebacterium pseudotuberculosis P54B96]	25.70	463	284	16	86	505	75	520	9e-18	97.8
rs:WP_024344084	DNA topoisomerase I [Streptococcus equinus].	24.42	520	319	17	7	504	31	498	9e-18	97.4
rs:WP_038184057	DNA topoisomerase I [Viridibacillus arenosi].	27.23	426	250	15	112	504	82	480	9e-18	97.4
tr:A0A0D6A520_9LACO	SubName: Full=Truncated topoisomerase {ECO:0000313|EMBL:BAQ57555.1};	29.32	266	166	11	279	531	15	271	9e-18	94.4
rs:WP_042823960	DNA topoisomerase I [Xanthomonas axonopodis].	23.65	592	350	20	7	563	6	530	9e-18	97.8
rs:WP_044147783	DNA topoisomerase I [Ehrlichia chaffeensis].	26.24	545	319	20	4	510	1	500	9e-18	97.8
rs:WP_028124627	DNA topoisomerase I [Eremococcus coleocola].	24.05	528	325	17	1	505	1	475	9e-18	97.4
rs:WP_027398235	DNA topoisomerase I [Anaerovorax odorimutans].	26.55	531	315	21	1	504	1	483	9e-18	97.4
rs:WP_028040262	DNA topoisomerase I [Caulobacter sp. URHA0033].	24.86	547	321	24	4	510	1	497	9e-18	97.8
tr:C3HSH8_BACTU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.04	355	225	9	271	606	19	358	9e-18	97.4
rs:WP_035146261	DNA topoisomerase III, partial [Lactobacillus sakei].	30.98	255	148	9	7	255	6	238	9e-18	94.0
tr:F3GKN5_PSESJ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH47638.1}; Flags: Fragment;	31.44	194	119	4	69	258	1	184	9e-18	92.4
rs:WP_047213735	DNA topoisomerase III, partial [Staphylococcus aureus].	31.34	201	131	5	364	559	26	224	9e-18	95.5
rs:WP_037948397	DNA topoisomerase I [Sulfuricurvum sp. MLSB].	25.89	448	282	13	86	505	49	474	9e-18	97.4
rs:WP_000629137	hypothetical protein, partial [Escherichia coli].	29.32	266	175	8	200	459	9	267	9e-18	94.4
rs:WP_003099575	DNA topoisomerase I [Streptococcus iniae].	23.61	521	322	16	7	504	30	497	9e-18	97.4
rs:WP_018869175	DNA topoisomerase I [Thioalkalivibrio sp. ALgr3].	25.00	540	313	21	7	505	6	494	9e-18	97.8
rs:WP_029274672	DNA topoisomerase I [Pedobacter borealis].	24.19	525	308	19	7	504	6	467	9e-18	97.8
rs:WP_028539393	DNA topoisomerase I [Paenibacillus sp. J14].	24.43	528	320	18	7	505	6	483	1e-17	97.4
rs:WP_015469497	DNA topoisomerase I [Bdellovibrio exovorus].	24.12	626	385	20	2	590	14	586	1e-17	97.8
rs:WP_033646108	hypothetical protein [Bacillus anthracis].	29.14	278	170	10	295	554	2	270	1e-17	95.5
rs:WP_003001121	DNA topoisomerase I [Sphingobacterium spiritivorum].	25.84	445	270	12	89	505	59	471	1e-17	97.4
rs:WP_033599499	DNA topoisomerase I [Enterococcus faecalis].	24.33	526	319	18	7	504	7	481	1e-17	97.4
rs:WP_002888489	DNA topoisomerase I [Streptococcus salivarius].	24.43	524	313	19	7	504	34	500	1e-17	97.4
rs:WP_025264359	DNA topoisomerase I [Wolbachia endosymbiont of Onchocerca volvulus].	24.91	550	312	22	7	510	4	498	1e-17	97.8
rs:WP_039472168	DNA topoisomerase I [Pedobacter kyungheensis].	24.15	530	302	19	7	504	6	467	1e-17	97.8
rs:WP_015638932	DNA topoisomerase I [Lactobacillus fermentum].	24.86	523	316	21	7	504	29	499	1e-17	97.4
rs:WP_006233149	topoisomerase I [Photobacterium profundum].	24.44	540	325	19	7	505	6	503	1e-17	97.8
rs:WP_001933799	DNA topoisomerase I [Streptococcus agalactiae].	24.66	519	319	19	7	504	25	492	1e-17	97.4
rs:WP_038305813	DNA topoisomerase I [Kingella kingae].	26.83	451	266	15	103	510	73	502	1e-17	97.4
rs:WP_029285403	DNA topoisomerase I [Pedobacter sp. R20-19].	24.00	525	309	18	7	504	6	467	1e-17	97.8
rs:WP_045175688	DNA topoisomerase I [Caldicellulosiruptor sp. Wai35.B1].	23.82	571	340	20	7	553	6	505	1e-17	97.4
rs:WP_039662514	DNA topoisomerase I [Campylobacter subantarcticus].	25.43	409	270	11	107	500	78	466	1e-17	97.4
tr:W6PRZ7_9BACE	SubName: Full=DNA topoisomerase III, Bacteroidales-type {ECO:0000313|EMBL:CDM06735.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDM06735.1};	28.85	253	158	6	4	248	1	239	1e-17	94.0
rs:WP_038634524	DNA topoisomerase I [Pseudomonas chlororaphis].	24.69	490	307	18	52	505	21	484	1e-17	97.4
rs:WP_044069353	DNA topoisomerase I [Pseudomonas aeruginosa].	25.35	497	294	19	86	553	58	506	1e-17	97.4
rs:WP_036386129	DNA topoisomerase I [Muricauda sp. MAR_2010_75].	24.52	522	308	18	7	504	6	465	1e-17	97.4
rs:WP_016271548	DNA topoisomerase III [Bacteroides vulgatus].	21.38	566	379	19	4	550	1	519	1e-17	97.1
rs:WP_016850507	DNA topoisomerase I [Xanthomonas axonopodis].	23.65	592	350	20	7	563	6	530	1e-17	97.4
rs:WP_036489275	DNA topoisomerase I, partial [Myxosarcina sp. GI1].	25.24	511	322	18	97	590	72	539	1e-17	97.1
rs:WP_016150334	DNA topoisomerase 1 [Citrobacter sp. KTE30].	24.95	537	321	20	7	505	6	498	1e-17	97.8
rs:WP_010331111	DNA topoisomerase I [Bacillus vallismortis].	27.25	422	255	15	112	504	82	480	1e-17	97.4
rs:WP_041108973	DNA topoisomerase I [Bacillus pumilus].	25.42	531	317	20	112	607	82	568	1e-17	97.4
rs:WP_036724648	DNA topoisomerase I [Paenibacillus sp. FSL R7-277].	25.05	527	315	22	7	504	6	481	1e-17	97.4
rs:WP_032611192	DNA topoisomerase I [Leclercia adecarboxylata].	24.72	534	325	20	7	505	6	497	1e-17	97.8
rs:WP_004836449	DNA topoisomerase I [Anaerococcus tetradius].	23.41	615	369	24	7	598	6	541	1e-17	97.4
rs:WP_028776179	DNA topoisomerase I [Shimazuella kribbensis].	25.19	524	318	19	7	504	6	481	1e-17	97.4
rs:WP_023913525	DNA topoisomerase I [Rhodobacter capsulatus].	25.14	525	322	20	4	505	1	477	1e-17	97.8
rs:WP_004207248	DNA topoisomerase I [Sphingobium yanoikuyae].	26.00	523	311	20	7	505	4	474	1e-17	97.4
rs:WP_031659876	DNA topoisomerase I [Listeria monocytogenes].	26.73	419	261	14	112	504	82	480	1e-17	97.4
rs:WP_019388943	DNA topoisomerase I [Kingella kingae].	27.05	451	265	15	103	510	73	502	1e-17	97.4
rs:WP_024329307	DNA topoisomerase I [Thioalkalivibrio sp. ALR17-21].	24.82	544	309	20	7	505	6	494	1e-17	97.8
rs:WP_017499589	DNA topoisomerase I [alpha proteobacterium LLX12A].	25.81	523	312	20	7	505	4	474	1e-17	97.4
tr:U2DT69_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.06	310	192	8	4	304	1	288	1e-17	94.4
tr:A0A081EW32_9EURY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.19	434	288	15	7	424	8	416	1e-17	95.9
rs:WP_039568675	DNA topoisomerase I [Xanthomonas axonopodis].	23.65	592	350	20	7	563	6	530	1e-17	97.4
rs:WP_008552945	DNA topoisomerase I [Pseudovibrio sp. JE062].	25.09	558	315	24	4	512	1	504	1e-17	97.8
rs:WP_039073950	DNA topoisomerase I [Bacillus sp. MSP13].	27.25	422	255	15	112	504	82	480	1e-17	97.4
rs:WP_031966320	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	1e-17	97.4
rs:WP_016647809	DNA topoisomerase I [Facklamia hominis].	24.28	523	319	20	7	505	7	476	1e-17	97.4
rs:WP_022560127	MULTISPECIES: DNA topoisomerase 1 [Xanthomonas].	23.65	592	350	20	7	563	6	530	1e-17	97.4
rs:WP_023119716	DNA topoisomerase I [Pseudomonas aeruginosa].	25.44	515	303	21	72	553	40	506	1e-17	97.1
rs:WP_027090882	DNA topoisomerase I [Cohnella thermotolerans].	25.38	532	307	21	7	504	6	481	1e-17	97.4
rs:WP_047166403	DNA topoisomerase I [Sphingomonas sp. Y57].	25.34	521	317	19	7	505	4	474	1e-17	97.4
rs:WP_019589952	MULTISPECIES: DNA topoisomerase I [Thioalkalivibrio].	24.86	535	320	19	7	505	6	494	1e-17	97.4
rs:WP_034687887	DNA topoisomerase I [Enterococcus mundtii].	23.90	523	325	18	7	504	7	481	1e-17	97.4
rs:WP_025633988	hypothetical protein [Vibrio parahaemolyticus].	23.38	633	366	24	8	547	5	611	1e-17	97.4
rs:WP_032027328	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	1e-17	97.4
rs:WP_008209996	DNA topoisomerase I [Rhodanobacter sp. 115].	24.86	543	316	17	7	505	6	500	1e-17	97.4
rs:WP_016185340	DNA topoisomerase I [Enterococcus sulfureus].	23.81	525	323	18	7	504	7	481	1e-17	97.4
rs:WP_041080448	DNA topoisomerase I [Staphylococcus saprophyticus].	25.38	524	313	20	7	504	6	477	1e-17	97.1
rs:WP_028093990	DNA topoisomerase I [Donghicola xiamenensis].	25.56	540	305	22	4	505	1	481	1e-17	97.4
rs:WP_007964211	DNA topoisomerase I [Xanthomonas fuscans].	23.65	592	350	20	7	563	6	530	1e-17	97.4
gp:CP006744_95	DNA topoisomerase [Bacillus anthracis str. SVA11]	29.14	278	170	10	295	554	2	270	1e-17	95.9
rs:WP_022976701	DNA topoisomerase I [Nevskia ramosa].	24.91	542	312	19	7	505	6	495	1e-17	97.4
rs:WP_036891898	DNA topoisomerase I, partial [Prevotella corporis].	25.65	347	217	9	5	333	3	326	1e-17	94.4
rs:WP_006101735	DNA topoisomerase I [Coleofasciculus chthonoplastes].	24.30	535	331	16	89	590	63	556	1e-17	97.4
rs:WP_018675578	hypothetical protein [Riemerella columbina].	28.37	289	180	12	279	552	93	369	1e-17	96.7
rs:WP_038312059	DNA topoisomerase I [Kingella kingae].	27.49	451	263	16	103	510	73	502	1e-17	97.4
rs:WP_045333127	DNA topoisomerase I [Enterobacter cloacae].	25.42	535	321	20	7	505	6	498	1e-17	97.4
rs:WP_039579585	DNA topoisomerase I [Xanthomonas axonopodis].	23.65	592	350	20	7	563	6	530	1e-17	97.4
rs:WP_022575798	topoisomerase I [Acinetobacter nosocomialis].	23.93	539	323	18	7	505	25	516	1e-17	97.4
rs:WP_024716065	DNA topoisomerase I [Bacillus tequilensis].	25.99	531	314	20	112	607	82	568	1e-17	97.1
rs:WP_007047795	DNA topoisomerase I [Subdoligranulum variabile].	25.14	529	317	21	7	505	5	484	1e-17	97.1
rs:WP_011225888	DNA topoisomerase I [Streptococcus thermophilus].	24.28	523	315	18	7	504	34	500	1e-17	97.1
tr:K2F5I4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.42	434	293	13	88	504	56	471	1e-17	97.1
rs:WP_022679588	DNA topoisomerase I [Sandarakinorhabdus limnophila].	25.09	546	309	24	7	510	4	491	1e-17	97.4
rs:WP_015652572	hypothetical protein [uncultured Sulfuricurvum sp. RIFRC-1].	24.77	432	289	10	92	505	61	474	1e-17	97.4
rs:WP_041768668	DNA topoisomerase I [Pseudovibrio sp. FO-BEG1].	25.49	557	314	24	4	512	1	504	1e-17	97.4
rs:WP_005927347	DNA topoisomerase I [Xanthomonas axonopodis].	23.65	592	350	20	7	563	6	530	1e-17	97.4
rs:WP_013990513	DNA topoisomerase I [Streptococcus salivarius].	24.43	524	313	19	7	504	34	500	1e-17	97.1
rs:WP_004463162	DNA topoisomerase I [Ruminiclostridium thermocellum].	25.52	572	331	18	7	553	6	507	1e-17	97.1
rs:WP_020985551	DNA topoisomerase I [Leptospira kmetyi].	25.42	531	302	21	7	505	5	473	1e-17	97.1
rs:WP_017727299	DNA topoisomerase I [Bacillus sp. L1(2012)].	24.81	528	314	19	7	504	6	480	1e-17	97.1
tr:C9CG38_ENTFC	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EEV43554.1};	33.17	202	121	4	375	563	1	201	1e-17	94.7
rs:WP_023429490	DNA topoisomerase I, archaeal [uncultured Acidilobus sp. JCHS].	25.00	564	336	23	6	541	2	506	1e-17	97.1
rs:WP_033963813	DNA topoisomerase I [Pseudomonas aeruginosa].	25.35	497	294	19	86	553	58	506	1e-17	97.1
tr:G8N977_9DEIN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.32	541	309	23	7	505	1	488	1e-17	97.4
rs:WP_015463664	DNA topoisomerase I [Xanthomonas axonopodis].	23.65	592	350	20	7	563	6	530	1e-17	97.4
rs:WP_038321536	DNA topoisomerase I [Kingella kingae].	27.05	451	265	15	103	510	73	502	1e-17	97.4
rs:WP_011630365	DNA topoisomerase I [Alkalilimnicola ehrlichii].	24.25	664	363	25	7	602	6	597	1e-17	97.4
rs:WP_032585425	DNA topoisomerase I [Bacteroides fragilis].	21.22	575	373	18	4	550	1	523	1e-17	96.7
rs:WP_012713672	DNA topoisomerase I [Sulfolobus islandicus].	22.96	540	341	18	42	564	53	534	1e-17	97.1
rs:WP_005911395	MULTISPECIES: DNA topoisomerase I [Xanthomonas].	23.65	592	350	20	7	563	6	530	1e-17	97.4
rs:WP_031491537	DNA topoisomerase I [Succinivibrio dextrinosolvens].	26.30	460	277	17	72	505	69	492	1e-17	97.4
rs:WP_037502696	DNA topoisomerase I [Sphingobacterium sp. ACCC 05744].	25.45	448	268	13	89	505	59	471	1e-17	97.4
rs:WP_014779492	DNA topoisomerase I [Thiocystis violascens].	24.44	536	322	19	7	505	4	493	1e-17	97.1
rs:WP_031961607	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	1e-17	97.4
rs:WP_010780938	DNA topoisomerase 1 [Enterococcus gilvus].	24.72	530	312	19	7	504	7	481	1e-17	97.1
rs:XP_008393932	PREDICTED: uncharacterized protein LOC103456080 isoform X1 [Malus domestica].	26.16	516	291	20	50	505	311	796	1e-17	97.4
rs:WP_031965029	DNA topoisomerase I [Acinetobacter baumannii].	24.12	539	322	18	7	505	25	516	1e-17	97.4
rs:WP_015954503	DNA topoisomerase I [Cyanothece sp. PCC 7424].	25.33	450	280	17	88	505	63	488	1e-17	97.1
rs:WP_022695662	DNA topoisomerase I [Ponticaulis koreensis].	25.09	542	304	24	4	505	1	480	1e-17	97.4
rs:WP_006915168	DNA topoisomerase I [Salinisphaera shabanensis].	25.77	551	318	21	7	512	6	510	1e-17	97.4
rs:WP_011052536	DNA topoisomerase I [Xanthomonas citri].	23.65	592	350	20	7	563	6	530	1e-17	97.4
rs:WP_045544581	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	1e-17	97.4
rs:WP_026479789	DNA topoisomerase I [Ahrensia sp. 13_GOM-1096m].	25.88	568	299	26	4	510	1	507	1e-17	97.4
rs:WP_040146339	DNA topoisomerase I [Legionella pneumophila].	24.91	542	311	16	7	505	6	494	1e-17	97.1
rs:WP_043895620	DNA topoisomerase I, partial [Porphyromonas gingivalis].	24.14	348	232	11	278	602	9	347	1e-17	95.5
rs:WP_004855164	DNA topoisomerase I [Acinetobacter gerneri].	24.91	538	320	19	7	505	25	517	1e-17	97.4
rs:WP_038329203	DNA topoisomerase I [Kingella kingae].	27.05	451	265	15	103	510	73	502	1e-17	97.1
rs:WP_012459087	DNA topoisomerase I [Sulfurihydrogenibium sp. YO3AOP1].	24.05	578	358	17	1	563	1	512	1e-17	97.1
rs:WP_037534984	DNA topoisomerase I [Sphingomonas sp. RIT328].	26.44	522	310	22	7	505	4	474	1e-17	97.4
rs:WP_027347737	DNA topoisomerase I [Helcococcus sueciensis].	25.04	579	342	21	7	564	6	513	1e-17	97.1
rs:WP_020875156	DNA topoisomerase I [Desulfococcus multivorans].	25.56	540	311	23	1	505	4	487	1e-17	97.1
rs:WP_016312454	DNA topoisomerase I [Paenibacillus barengoltzii].	24.43	528	320	18	7	505	6	483	1e-17	97.1
rs:WP_031764727	DNA topoisomerase I [Staphylococcus aureus].	25.71	529	308	22	7	505	6	479	1e-17	97.1
rs:WP_002686763	DNA topoisomerase I [Bergeyella zoohelcum].	24.05	528	300	19	7	504	6	462	1e-17	97.4
rs:WP_034979206	DNA topoisomerase I [Lactobacillus sp. wkB10].	24.09	523	322	17	7	505	15	486	1e-17	97.1
rs:WP_011216475	DNA topoisomerase I [Legionella pneumophila].	24.91	542	311	16	7	505	6	494	1e-17	97.1
rs:WP_022076495	DNA topoisomerase [Clostridium sp. CAG:571].	24.68	624	337	25	7	585	6	541	1e-17	96.7
rs:WP_018048827	hypothetical protein [Nitrospina sp. AB-629-B18].	26.06	545	311	22	7	510	32	525	1e-17	97.1
rs:WP_038310428	DNA topoisomerase I [Kingella kingae].	27.05	451	265	15	103	510	73	502	1e-17	97.1
rs:WP_014844720	DNA topoisomerase I [Legionella pneumophila].	24.91	542	311	16	7	505	6	494	1e-17	97.1
rs:WP_004182436	DNA topoisomerase I [Streptococcus salivarius].	24.43	524	313	19	7	504	34	500	1e-17	97.1
rs:WP_014634563	DNA topoisomerase I [Streptococcus salivarius].	24.43	524	313	19	7	504	34	500	1e-17	97.1
rs:WP_038839607	DNA topoisomerase I [Legionella pneumophila].	24.91	542	311	16	7	505	6	494	1e-17	97.1
tr:Q6WWY9_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.45	499	291	20	86	553	50	498	1e-17	96.7
rs:WP_039126264	DNA topoisomerase I [Gilliamella apicola].	25.09	534	323	21	7	505	6	497	1e-17	97.4
rs:WP_000024270	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	1e-17	97.4
rs:WP_002891063	DNA topoisomerase I [Streptococcus salivarius].	24.90	526	308	20	7	504	34	500	1e-17	97.1
rs:WP_015017017	DNA topoisomerase I [Streptococcus dysgalactiae].	23.80	521	321	16	7	504	39	506	1e-17	97.1
rs:WP_018946671	DNA topoisomerase I [Thioalkalivibrio sp. AKL17].	24.82	544	309	20	7	505	6	494	1e-17	97.4
rs:WP_031285200	DNA topoisomerase I [Pseudomonas aeruginosa].	24.55	505	288	19	86	553	58	506	1e-17	96.7
rs:WP_004754292	DNA topoisomerase I [Acinetobacter sp. ANC 3789].	25.85	441	273	15	88	505	109	518	1e-17	97.4
rs:WP_008534745	DNA topoisomerase I [Streptococcus sp. C150].	24.43	524	313	19	7	504	34	500	1e-17	97.1
gpu:CP011341_608	DNA topoisomerase I [Rhodococcus aetherivorans]	24.27	585	350	20	7	550	19	551	1e-17	97.4
tr:V8EN21_PSEAI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	25.45	495	296	19	86	553	10	458	1e-17	96.7
rs:WP_007555187	DNA topoisomerase I [Dialister micraerophilus].	24.14	526	321	18	7	504	35	510	1e-17	97.1
rs:WP_027266315	DNA topoisomerase I [Legionella pneumophila].	24.91	542	311	16	7	505	6	494	1e-17	97.1
rs:WP_006499529	topoisomerase [Lactobacillus mucosae].	24.63	467	319	13	7	455	6	457	1e-17	97.1
rs:WP_014633069	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.43	524	313	19	7	504	34	500	1e-17	97.1
rs:WP_021144079	DNA topoisomerase I [Streptococcus sp. HSISS1].	24.43	524	313	19	7	504	34	500	1e-17	97.1
rs:WP_010948299	DNA topoisomerase I [Legionella pneumophila].	24.91	542	311	16	7	505	6	494	1e-17	97.1
rs:WP_005302100	DNA topoisomerase I [Acinetobacter sp. NIPH 542].	23.55	535	330	18	7	505	25	516	1e-17	97.1
rs:WP_036783079	DNA topoisomerase I [Polaribacter sp. Hel1_33_49].	27.24	525	288	23	7	504	6	463	1e-17	97.1
rs:WP_015955838	DNA topoisomerase I [Cyanothece sp. PCC 7424].	25.56	450	273	17	91	505	66	488	1e-17	97.1
rs:WP_003670912	DNA topoisomerase I [Lactobacillus reuteri].	24.19	525	317	19	7	504	25	495	1e-17	97.1
rs:WP_007014845	DNA topoisomerase I [Novosphingobium pentaromativorans].	26.09	529	304	22	7	505	4	475	1e-17	97.1
rs:WP_012995298	DNA topoisomerase I [Thermoanaerobacter italicus].	24.65	568	339	21	7	553	6	505	1e-17	97.1
rs:WP_026209402	DNA topoisomerase I [Corynebacterium caspium].	26.43	473	262	19	97	505	85	535	1e-17	97.4
rs:WP_006062743	DNA topoisomerase I [Corynebacterium durum].	25.97	466	282	16	86	505	74	522	1e-17	97.4
rs:WP_031994209	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	1e-17	97.1
rs:WP_036805757	DNA topoisomerase I [Photorhabdus luminescens].	24.78	456	299	15	69	505	68	498	1e-17	97.1
rs:WP_010200378	DNA topoisomerase III, partial [Pseudomonas amygdali].	36.92	130	74	4	8	137	5	126	1e-17	90.5
rs:WP_011947523	DNA topoisomerase I [Legionella pneumophila].	24.91	542	311	16	7	505	6	494	1e-17	97.1
rs:WP_031872092	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	1e-17	96.7
rs:WP_004911045	DNA topoisomerase I subunit omega [Providencia rettgeri].	26.76	441	271	17	88	505	90	501	1e-17	97.1
rs:WP_002416968	toprim domain protein, partial [Enterococcus faecalis].	32.21	208	125	8	5	205	3	201	1e-17	92.0
rs:WP_014079538	DNA topoisomerase I [Roseburia hominis].	24.76	529	314	21	7	504	6	481	1e-17	96.7
rs:WP_004794819	DNA topoisomerase I [Acinetobacter sp. NIPH 817].	23.55	535	330	18	7	505	25	516	1e-17	97.1
rs:WP_033795164	DNA topoisomerase, partial [Enterococcus faecium].	33.33	201	120	4	376	563	26	225	1e-17	94.7
rs:WP_032062207	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	97.1
rs:WP_032025980	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	97.1
rs:WP_032133092	DNA topoisomerase I [Kingella kingae].	27.29	447	261	15	107	510	77	502	2e-17	97.1
rs:WP_004976132	DNA topoisomerase I [Acinetobacter towneri].	25.74	439	276	14	88	505	108	517	2e-17	97.1
rs:WP_013687041	DNA topoisomerase I [Fluviicola taffensis].	23.57	526	309	17	7	504	6	466	2e-17	97.1
rs:WP_017398783	topoisomerase I [Acinetobacter pittii].	23.75	539	324	18	7	505	25	516	2e-17	97.1
rs:WP_031959721	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	97.1
rs:WP_003732799	DNA topoisomerase I [Listeria monocytogenes].	26.90	420	259	15	112	504	82	480	2e-17	96.7
rs:WP_018360551	hypothetical protein [Porphyromonas macacae].	25.00	576	315	22	7	541	6	505	2e-17	97.1
rs:WP_031277332	DNA topoisomerase I [Pseudomonas aeruginosa].	25.45	495	296	19	86	553	58	506	2e-17	96.7
tr:E4Q5B6_CALOW	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.91	619	370	22	7	599	5	548	2e-17	96.7
rs:WP_019313223	DNA topoisomerase I [Streptococcus mutans].	25.52	525	307	22	7	504	24	491	2e-17	96.7
rs:WP_023060391	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	97.1
rs:WP_003766673	DNA topoisomerase I [Listeria innocua].	26.49	419	262	14	112	504	82	480	2e-17	96.7
rs:WP_003738814	DNA topoisomerase I [Listeria monocytogenes].	26.73	419	261	14	112	504	82	480	2e-17	96.7
rs:WP_028265367	DNA topoisomerase I [Arthrobacter sp. MA-N2].	25.54	552	313	21	7	505	12	518	2e-17	97.1
tr:E1X628_BACMS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.29	560	328	22	1	512	74	585	2e-17	97.1
rs:WP_032012359	DNA topoisomerase I [Acinetobacter baumannii].	23.75	539	324	18	7	505	25	516	2e-17	97.1
rs:WP_046080869	DNA topoisomerase I [Escherichia fergusonii].	25.27	459	303	15	64	505	63	498	2e-17	97.1
rs:WP_035401765	DNA topoisomerase I, partial [Chlorobium sp. GBChlB].	24.15	530	317	22	7	500	9	489	2e-17	97.1
rs:WP_031925401	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	2e-17	96.7
rs:WP_036138397	DNA topoisomerase I [Luteibacter sp. 9135].	24.77	533	323	19	7	505	6	494	2e-17	97.1
rs:WP_002352642	DNA topoisomerase, partial [Enterococcus faecium].	32.84	201	121	4	376	563	42	241	2e-17	93.6
rs:WP_014842657	DNA topoisomerase I [Legionella pneumophila].	24.91	542	311	16	7	505	6	494	2e-17	97.1
rs:WP_031979792	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	97.1
rs:WP_003715207	DNA topoisomerase I [Lactobacillus oris].	25.00	520	319	21	7	504	31	501	2e-17	96.7
rs:WP_041978506	hypothetical protein [Pyrinomonas methylaliphatogenes].	24.24	561	327	23	7	514	6	521	2e-17	97.1
rs:WP_007115615	DNA topoisomerase I, partial [Enhydrobacter aerosaccus].	25.60	418	267	15	107	505	157	549	2e-17	97.1
rs:WP_039667896	DNA topoisomerase I [Campylobacter lari].	25.43	409	270	11	107	500	78	466	2e-17	96.7
rs:WP_010863937	DNA topoisomerase I subunit omega [Plesiomonas shigelloides].	24.08	544	323	19	7	505	6	504	2e-17	97.1
rs:WP_019723732	DNA topoisomerase I [Enterococcus mundtii].	25.19	524	317	20	7	504	7	481	2e-17	96.7
rs:WP_027267691	DNA topoisomerase I [Legionella pneumophila].	24.91	542	311	16	7	505	6	494	2e-17	97.1
tr:A0A0A8H6T1_CAMLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.43	409	270	11	107	500	77	465	2e-17	96.7
rs:WP_005066066	MULTISPECIES: DNA topoisomerase I [Acinetobacter calcoaceticus/baumannii complex].	23.75	539	324	18	7	505	25	516	2e-17	97.1
rs:WP_032043705	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	97.1
rs:WP_037506680	DNA topoisomerase I [Sphingobium yanoikuyae].	26.00	523	311	20	7	505	4	474	2e-17	97.1
rs:WP_015199931	DNA topoisomerase I [Calothrix parietina].	25.21	484	298	18	97	540	72	531	2e-17	96.7
rs:WP_038307892	DNA topoisomerase I [Kingella kingae].	27.29	447	261	15	107	510	77	502	2e-17	97.1
rs:WP_022648322	MULTISPECIES: DNA topoisomerase 1 [Enterobacter].	25.42	535	321	20	7	505	6	498	2e-17	97.1
rs:WP_023300259	DNA topoisomerase 1 [Enterobacter cloacae].	25.42	535	321	20	7	505	6	498	2e-17	97.1
rs:WP_031684974	DNA topoisomerase I [Pseudomonas aeruginosa].	25.35	497	294	19	86	553	58	506	2e-17	96.7
rs:WP_029712355	hypothetical protein, partial [BRC1 bacterium SCGC AAA257-C11].	23.02	556	337	20	7	531	8	503	2e-17	96.7
rs:WP_038302802	DNA topoisomerase I [Kingella kingae].	27.29	447	261	15	107	510	77	502	2e-17	96.7
rs:WP_019021654	DNA topoisomerase I [Thioalkalivibrio sp. ALE23].	24.86	535	320	19	7	505	6	494	2e-17	97.1
rs:WP_044474989	DNA topoisomerase III, partial [Xanthomonas campestris].	30.28	218	141	5	8	225	5	211	2e-17	92.4
rs:WP_031950010	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	97.1
rs:WP_038314451	DNA topoisomerase I [Kingella kingae].	27.29	447	261	15	107	510	77	502	2e-17	96.7
sp:TOP1_STAA3	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.76	528	309	22	7	505	6	479	2e-17	96.7
rs:WP_012951572	DNA topoisomerase I [Listeria monocytogenes].	26.90	420	259	15	112	504	82	480	2e-17	96.7
rs:WP_003787925	DNA topoisomerase I [Kingella kingae].	27.29	447	261	15	107	510	77	502	2e-17	96.7
rs:WP_029052236	DNA topoisomerase I, partial [Staphylococcus aureus].	25.81	527	308	22	7	504	6	478	2e-17	96.7
rs:WP_000024268	topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	97.1
rs:WP_016803628	topoisomerase I [Acinetobacter nosocomialis].	23.93	539	323	18	7	505	25	516	2e-17	97.1
rs:WP_000024269	topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	97.1
rs:WP_031952294	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	97.1
rs:WP_016168270	DNA topoisomerase I [Acinetobacter tandoii].	26.88	439	271	15	88	505	110	519	2e-17	97.1
rs:WP_033917940	DNA topoisomerase I [Enterococcus faecalis].	24.14	526	320	18	7	504	7	481	2e-17	96.7
rs:WP_031994669	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	97.1
rs:WP_004738038	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	97.1
rs:WP_005172815	DNA topoisomerase I [Acinetobacter sp. NIPH 713].	24.58	537	323	18	7	505	26	518	2e-17	97.1
rs:WP_009924617	DNA topoisomerase I [Listeria monocytogenes].	26.73	419	261	14	112	504	82	480	2e-17	96.7
rs:WP_042923545	DNA topoisomerase I [Kingella kingae].	27.29	447	261	15	107	510	77	502	2e-17	96.7
rs:WP_043044512	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	2e-17	96.7
rs:WP_032058555	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	97.1
rs:WP_004842577	DNA topoisomerase I [Acinetobacter baumannii].	23.75	539	324	18	7	505	25	516	2e-17	97.1
rs:WP_023103391	DNA topoisomerase I [Pseudomonas aeruginosa].	25.52	478	286	18	99	553	76	506	2e-17	96.7
rs:WP_036872829	DNA topoisomerase I [Porphyromonas macacae].	25.00	576	315	22	7	541	6	505	2e-17	96.7
rs:WP_041738085	DNA topoisomerase I [Caldicellulosiruptor owensensis].	23.91	619	370	22	7	599	6	549	2e-17	96.7
rs:WP_031947281	DNA topoisomerase I [Acinetobacter baumannii].	23.75	539	324	18	7	505	25	516	2e-17	97.1
rs:WP_040163317	DNA topoisomerase I [Microbacterium sp. G3].	23.80	584	347	22	7	550	8	533	2e-17	97.1
rs:WP_014294544	DNA topoisomerase I [Streptococcus macedonicus].	24.09	635	369	24	7	607	32	587	2e-17	96.7
rs:WP_034548728	DNA topoisomerase I [Carnobacterium alterfunditum].	24.25	532	324	18	1	504	1	481	2e-17	96.7
rs:WP_040133195	DNA topoisomerase I [Providencia stuartii].	26.54	437	277	14	88	505	86	497	2e-17	97.1
tr:D4FWK7_BACNB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.09	530	320	19	112	607	84	570	2e-17	96.7
rs:WP_031921185	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	2e-17	96.7
rs:WP_016424904	DNA topoisomerase 1 [Staphylococcus sp. HGB0015].	24.62	528	313	20	7	504	6	478	2e-17	96.7
rs:WP_021265626	DNA topoisomerase I [Salmonella enterica].	25.73	443	270	16	91	505	58	469	2e-17	96.7
rs:WP_036798385	DNA topoisomerase I [Photobacterium sp. AK15].	25.93	459	289	17	69	505	74	503	2e-17	97.1
rs:WP_003212237	DNA topoisomerase I [Bacillus pumilus].	26.65	424	261	14	109	504	79	480	2e-17	96.7
rs:WP_003517938	DNA topoisomerase I [Ruminiclostridium thermocellum].	25.52	572	331	18	7	553	6	507	2e-17	96.7
rs:WP_033993318	DNA topoisomerase I [Pseudomonas aeruginosa].	25.05	499	293	19	86	553	58	506	2e-17	96.3
rs:WP_033798018	hypothetical protein [Bacillus mycoides].	30.24	205	125	6	5	207	4	192	2e-17	92.0
rs:WP_003829064	DNA topoisomerase I [Citrobacter freundii].	24.51	559	332	19	5	545	3	489	2e-17	96.7
rs:WP_044558127	hypothetical protein, partial [Bacteriovorax marinus].	24.29	560	328	22	1	512	60	571	2e-17	96.7
rs:WP_024332001	DNA topoisomerase I [Actinomyces neuii].	24.14	580	340	17	7	535	11	541	2e-17	97.1
rs:WP_046397491	DNA topoisomerase I [Photorhabdus luminescens].	24.78	456	299	15	69	505	68	498	2e-17	97.1
rs:WP_016669102	DNA topoisomerase I [Propionibacterium sp. oral taxon 192].	25.04	559	314	24	7	505	9	522	2e-17	97.1
rs:WP_012581412	DNA topoisomerase I [Listeria monocytogenes].	26.73	419	261	14	112	504	82	480	2e-17	96.7
rs:WP_014600791	DNA topoisomerase I [Listeria monocytogenes].	26.90	420	259	15	112	504	82	480	2e-17	96.7
rs:WP_046619715	DNA topoisomerase I [Enterobacter cloacae].	25.42	535	321	20	7	505	6	498	2e-17	96.7
tr:E3C6K9_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	520	319	21	7	504	6	476	2e-17	96.7
rs:WP_017385701	MULTISPECIES: topoisomerase I [Acinetobacter].	23.75	539	324	18	7	505	25	516	2e-17	96.7
rs:WP_017482015	topoisomerase I [Acinetobacter calcoaceticus].	23.75	539	324	18	7	505	25	516	2e-17	96.7
tr:S2UTZ2_LACPA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.61	402	244	15	129	504	10	390	2e-17	96.3
rs:WP_018379577	DNA topoisomerase I [Streptococcus thoraltensis].	24.01	529	310	20	7	504	30	497	2e-17	96.7
rs:WP_039821720	DNA topoisomerase I [Nocardia testacea].	25.21	591	341	22	7	550	19	555	2e-17	97.1
rs:WP_016252326	DNA topoisomerase 1 [Enterococcus cecorum].	23.66	524	325	18	7	504	7	481	2e-17	96.7
rs:WP_010991808	TraB protein [uncultured bacterium].	23.66	524	330	16	43	544	25	500	2e-17	96.7
rs:WP_009536215	DNA topoisomerase I [Oribacterium asaccharolyticum].	25.19	528	312	22	7	504	6	480	2e-17	96.3
rs:WP_019570205	DNA topoisomerase I [Thioalkalivibrio sp. ALE11].	24.86	535	320	19	7	505	6	494	2e-17	96.7
rs:WP_006684311	topoisomerase I [Citrobacter youngae].	24.49	535	326	19	7	505	6	498	2e-17	96.7
rs:WP_032622442	DNA topoisomerase I [Lelliottia amnigena].	25.42	535	321	20	7	505	6	498	2e-17	96.7
rs:WP_043857492	DNA topoisomerase 1 [Bacillus subtilis].	25.09	530	320	19	112	607	82	568	2e-17	96.7
rs:WP_008858871	DNA topoisomerase I [Dialister succinatiphilus].	23.92	531	322	19	5	505	36	514	2e-17	96.7
rs:WP_002115027	MULTISPECIES: topoisomerase I [Acinetobacter calcoaceticus/baumannii complex].	23.75	539	324	18	7	505	25	516	2e-17	96.7
rs:WP_004710690	DNA topoisomerase I [Acinetobacter nosocomialis].	23.93	539	323	18	7	505	25	516	2e-17	96.7
rs:WP_022436798	DNA topoisomerase [Prevotella sp. CAG:279].	24.48	576	328	22	7	547	43	546	2e-17	96.7
rs:WP_024121390	DNA topoisomerase I [Bacillus mojavensis].	27.01	422	256	15	112	504	82	480	2e-17	96.7
rs:WP_002053435	MULTISPECIES: topoisomerase I [Acinetobacter calcoaceticus/baumannii complex].	23.93	539	323	18	7	505	25	516	2e-17	96.7
rs:WP_040564319	DNA topoisomerase I [Kingella denitrificans].	27.13	446	267	17	97	505	67	491	2e-17	96.7
rs:WP_017486547	DNA topoisomerase I [Methylobacterium sp. MB200].	25.05	551	320	23	4	510	1	502	2e-17	96.7
rs:WP_044832579	DNA topoisomerase I [Thalassomonas actiniarum].	24.68	543	321	20	7	505	6	504	2e-17	96.7
rs:WP_029741796	DNA topoisomerase I [Enterobacter asburiae].	25.73	443	270	16	91	505	58	469	2e-17	96.3
rs:WP_037503922	DNA topoisomerase I, partial [Sphingomonas jaspsi].	25.66	530	320	21	7	510	4	485	2e-17	96.7
rs:WP_016264249	DNA topoisomerase I [Pseudomonas aeruginosa].	25.25	495	297	18	86	553	58	506	2e-17	96.3
rs:WP_031954307	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	96.7
rs:WP_044131834	DNA topoisomerase I, partial [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	2e-17	96.3
rs:WP_031666351	DNA topoisomerase I [Listeria monocytogenes].	26.97	419	260	14	112	504	82	480	2e-17	96.3
rs:WP_018777017	MULTISPECIES: DNA topoisomerase I [Arthrobacter].	25.73	548	317	19	7	505	12	518	2e-17	96.7
rs:WP_024667726	hypothetical protein, partial [Pseudomonas syringae].	36.92	130	74	4	8	137	5	126	2e-17	90.1
rs:WP_031929655	DNA topoisomerase 1 [Staphylococcus aureus].	25.95	528	308	22	7	505	6	479	2e-17	96.3
rs:WP_042415599	DNA topoisomerase I [Geomicrobium sp. JCM 19038].	24.30	609	365	24	7	586	6	547	2e-17	96.3
tr:A0A0E1X6A0_STAAU	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EFH94907.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFH94907.1};	25.95	528	308	22	7	505	8	481	2e-17	96.3
rs:WP_031891318	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	2e-17	96.3
rs:WP_031844621	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	2e-17	96.3
rs:WP_044740086	DNA topoisomerase I [Bacillus mycoides].	26.88	439	271	15	88	505	110	519	2e-17	96.7
rs:WP_037519864	DNA topoisomerase I [Sphingobium yanoikuyae].	25.81	523	312	20	7	505	4	474	2e-17	96.7
rs:WP_022132257	DNA topoisomerase [Clostridium sp. CAG:242].	25.86	526	314	21	7	505	61	537	2e-17	96.7
rs:WP_016144255	DNA topoisomerase I [Acinetobacter pittii].	23.75	539	324	18	7	505	25	516	2e-17	96.7
rs:WP_034637643	DNA topoisomerase I [Desulfovibrio cuneatus].	23.50	549	305	22	63	544	21	521	2e-17	96.3
rs:WP_038318343	DNA topoisomerase I [Kingella kingae].	27.29	447	261	15	107	510	77	502	2e-17	96.7
rs:WP_020359163	DNA topoisomerase I [Chlamydia psittaci].	24.54	542	319	21	7	505	6	500	2e-17	96.7
rs:WP_040233192	DNA topoisomerase I [Citrobacter sp. CIP 55.13].	24.49	535	326	19	7	505	6	498	2e-17	96.7
rs:WP_001548566	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	8	481	2e-17	96.3
rs:WP_032054351	DNA topoisomerase I [Acinetobacter baumannii].	23.75	539	324	18	7	505	25	516	2e-17	96.7
tr:F0EZX1_9NEIS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.13	446	267	17	97	505	82	506	2e-17	96.7
tr:G4ADB7_AGGAC	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGY43437.1};	27.03	259	167	8	7	252	4	253	2e-17	93.2
tr:W8JMV0_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.54	542	319	21	7	505	9	503	2e-17	96.7
rs:WP_033855510	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	96.7
rs:WP_015505597	DNA topoisomerase I [Erwinia amylovora].	25.73	443	270	16	91	505	58	469	2e-17	96.3
rs:WP_010431771	topoisomerase I [Enterobacter mori].	25.23	535	322	20	7	505	6	498	2e-17	96.7
rs:WP_039929908	DNA topoisomerase I, partial [Lactobacillus oris].	25.00	520	319	21	7	504	24	494	2e-17	96.3
rs:WP_039210129	DNA topoisomerase I [Acinetobacter baumannii].	24.12	539	322	18	7	505	25	516	2e-17	96.7
tr:K1SDD2_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC45401.1}; Flags: Fragment;	24.93	357	236	9	4	351	1	334	2e-17	93.6
rs:WP_047242530	DNA topoisomerase I [Enterococcus cecorum].	23.66	524	325	18	7	504	7	481	2e-17	96.3
rs:WP_022935905	DNA topoisomerase I [Mycoplasma orale].	24.83	431	281	12	93	504	64	470	2e-17	96.3
rs:WP_039874304	DNA topoisomerase I [Paenibacillus sp. FSL R7-0273].	24.91	530	316	20	5	504	4	481	2e-17	96.3
rs:WP_035341963	DNA topoisomerase I [Dickeya sp. DW 0440].	25.70	463	283	20	79	510	77	509	2e-17	96.7
rs:WP_038500965	DNA topoisomerase I [Chlamydia avium].	24.54	542	319	21	7	505	6	500	2e-17	96.7
tr:L8JIZ1_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.93	459	289	17	69	505	44	473	2e-17	96.7
rs:WP_039808869	DNA topoisomerase I [Jeotgalibacillus sp. D5].	25.38	528	314	20	7	505	6	482	2e-17	96.3
rs:WP_034086288	DNA topoisomerase I [Pseudomonas aeruginosa].	25.52	478	286	18	99	553	76	506	2e-17	96.3
rs:WP_017393949	MULTISPECIES: topoisomerase I [Acinetobacter calcoaceticus/baumannii complex].	23.93	539	323	18	7	505	25	516	2e-17	96.7
rs:WP_003727517	DNA topoisomerase I [Listeria monocytogenes].	26.73	419	261	14	112	504	82	480	2e-17	96.3
rs:WP_011174621	DNA topoisomerase I [Candidatus Protochlamydia amoebophila].	24.58	594	348	22	7	564	6	535	2e-17	96.7
rs:WP_038663823	DNA topoisomerase I [Sphingomonas taxi].	26.53	524	307	20	7	505	4	474	2e-17	96.7
rs:WP_046104204	DNA topoisomerase I [Devosia chinhatensis].	26.06	541	304	21	4	505	1	484	2e-17	96.7
rs:WP_037377166	DNA topoisomerase I [Selenomonas ruminantium].	24.63	536	312	23	5	505	35	513	2e-17	96.3
rs:WP_046101912	DNA topoisomerase I [Pantoea anthophila].	25.80	469	278	17	69	505	68	498	2e-17	96.7
rs:WP_019789487	DNA topoisomerase I, partial [Streptococcus sobrinus].	25.59	422	261	13	109	504	1	395	2e-17	95.9
rs:WP_016390852	MULTISPECIES: DNA topoisomerase I [Cycloclasticus].	25.79	539	311	19	7	505	5	494	2e-17	96.3
rs:WP_047341422	DNA topoisomerase I [Enterococcus cecorum].	23.66	524	325	18	7	504	7	481	2e-17	96.3
rs:WP_043041331	DNA topoisomerase I [Acinetobacter baumannii].	23.75	539	324	18	7	505	25	516	2e-17	96.7
rs:WP_011371807	DNA topoisomerase I [Sulfurimonas denitrificans].	24.05	524	321	18	7	505	4	475	2e-17	96.3
rs:WP_009089965	topoisomerase I [Pantoea sp. Sc1].	25.80	469	278	17	69	505	68	498	2e-17	96.7
rs:WP_023519488	DNA topoisomerase I [Enterococcus mundtii].	25.00	524	318	20	7	504	7	481	2e-17	96.3
rs:WP_025981576	DNA topoisomerase I [Pseudomonas aeruginosa].	25.52	478	286	18	99	553	76	506	2e-17	96.3
rs:WP_033867932	DNA topoisomerase I [Staphylococcus aureus].	25.95	528	308	22	7	505	6	479	2e-17	96.3
rs:WP_000774791	DNA topoisomerase I [Staphylococcus aureus].	25.95	528	308	22	7	505	6	479	2e-17	96.3
rs:WP_015262991	DNA topoisomerase I [Desulfitobacterium dichloroeliminans].	25.81	585	323	22	5	555	4	511	2e-17	96.3
rs:WP_031378741	DNA topoisomerase I [Bacillus amyloliquefaciens].	26.37	421	260	14	112	504	82	480	2e-17	96.3
rs:WP_004806974	DNA topoisomerase I [Actinomyces neuii].	24.74	578	339	19	7	535	11	541	2e-17	96.7
rs:WP_033991699	DNA topoisomerase I [Pseudomonas aeruginosa].	24.55	505	288	19	86	553	58	506	2e-17	96.3
rs:WP_032048135	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	96.7
rs:WP_014479776	DNA topoisomerase I [Bacillus subtilis].	25.09	530	320	19	112	607	82	568	2e-17	96.3
rs:WP_002132868	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	2e-17	96.7
rs:WP_022672346	DNA topoisomerase I [Sphingopyxis baekryungensis].	26.70	528	301	21	7	505	4	474	2e-17	96.7
rs:WP_014967754	DNA topoisomerase I [Gottschalkia acidurici].	23.90	569	341	20	7	553	6	504	2e-17	96.3
rs:WP_038357410	DNA topoisomerase I, partial [Bacillus anthracis].	24.90	526	318	20	7	505	6	481	2e-17	95.5
rs:WP_003792156	DNA topoisomerase I [Kingella kingae].	26.83	451	266	15	103	510	73	502	2e-17	96.3
rs:WP_023110980	DNA topoisomerase I [Pseudomonas aeruginosa].	25.52	478	286	18	99	553	76	506	2e-17	95.9
rs:WP_033162674	DNA topoisomerase I [Sharpea azabuensis].	22.31	641	384	22	1	605	1	563	2e-17	96.3
tr:Q1H4T9_METFK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.23	543	305	21	7	504	5	491	2e-17	96.3
rs:WP_013303640	DNA topoisomerase I [Ignisphaera aggregans].	23.25	628	390	26	7	598	9	580	2e-17	96.3
rs:WP_000366820	hypothetical protein, partial [Acinetobacter baumannii].	35.43	175	102	6	8	180	5	170	2e-17	91.3
rs:WP_036850036	DNA topoisomerase I [Porphyromonas macacae].	25.00	576	315	22	7	541	6	505	2e-17	96.3
rs:WP_024947298	DNA topoisomerase I [Pseudomonas aeruginosa].	25.05	495	298	18	86	553	58	506	2e-17	95.9
rs:WP_028036917	DNA topoisomerase I [Candidatus Pelagibacter ubique].	24.16	534	319	19	7	505	4	486	2e-17	96.3
gp:CP003695_2276	DNA topoisomerase I [Bacillus subtilis subsp. subtilis str. BSP1]	25.09	530	320	19	112	607	87	573	2e-17	96.3
rs:WP_020254513	hypothetical protein [Parcubacteria bacterium SCGC AAA036-E14].	26.14	417	272	14	107	505	75	473	2e-17	96.3
rs:WP_042166570	DNA topoisomerase I [Pseudomonas aeruginosa].	25.25	495	297	18	86	553	58	506	2e-17	95.9
rs:WP_038428950	DNA topoisomerase I [Bacillus subtilis].	25.09	530	320	19	112	607	82	568	2e-17	96.3
rs:WP_001701436	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	26.77	437	272	16	90	505	3	412	2e-17	96.3
rs:WP_037031563	DNA topoisomerase I [Psychrobacter phenylpyruvicus].	25.66	456	283	19	84	505	85	518	2e-17	96.3
rs:WP_038036917	DNA topoisomerase I, partial [Thermopetrobacter sp. TC1].	24.11	647	363	25	7	603	5	573	2e-17	96.3
rs:WP_029039839	DNA topoisomerase I [Cucumibacter marinus].	25.93	540	310	20	4	505	1	488	2e-17	96.3
rs:WP_032009232	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	96.3
rs:WP_031972313	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	96.3
rs:WP_011539659	DNA topoisomerase I [Ruegeria sp. TM1040].	24.91	570	308	25	4	510	1	513	3e-17	96.3
rs:WP_030425043	DNA topoisomerase I, partial [Acinetobacter baumannii].	23.93	539	323	18	7	505	12	503	3e-17	96.3
tr:G4EWD2_BACIU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.09	530	320	19	112	607	75	561	3e-17	95.9
rs:WP_046418721	DNA topoisomerase I [Xylella fastidiosa].	25.80	593	336	22	7	563	6	530	3e-17	96.3
rs:WP_029547225	DNA topoisomerase I [Rhodococcus sp. BCP1].	24.27	585	350	20	7	550	19	551	3e-17	96.7
rs:WP_007409771	MULTISPECIES: DNA topoisomerase I [Bacillus].	26.37	421	260	14	112	504	82	480	3e-17	95.9
rs:WP_034063959	DNA topoisomerase I [Pseudomonas aeruginosa].	25.35	497	294	19	86	553	58	506	3e-17	95.9
rs:WP_042916887	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	25.25	499	294	19	86	553	58	508	3e-17	95.9
rs:WP_015006903	MULTISPECIES: DNA topoisomerase I [Cycloclasticus].	25.79	539	311	19	7	505	5	494	3e-17	96.3
rs:WP_014663959	MULTISPECIES: DNA topoisomerase I [Bacillus].	25.09	530	320	19	112	607	82	568	3e-17	95.9
rs:WP_002483473	DNA topoisomerase 1 [Staphylococcus saprophyticus].	25.38	524	313	20	7	504	6	477	3e-17	95.9
rs:WP_013555570	DNA topoisomerase I [Deinococcus maricopensis].	25.58	430	269	14	107	505	90	499	3e-17	95.9
rs:WP_035662616	DNA topoisomerase I [Bacillus akibai].	25.52	525	315	19	7	504	6	481	3e-17	95.9
rs:WP_038334579	DNA topoisomerase I [Kingella kingae].	27.29	447	261	15	107	510	77	502	3e-17	96.3
rs:WP_011042034	topoisomerase I [Colwellia psychrerythraea].	27.02	544	321	22	88	606	94	586	3e-17	96.3
tr:J5UYF0_ENTFC	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EJX43737.1}; Flags: Fragment;	33.94	165	99	3	376	531	32	195	3e-17	91.3
rs:WP_018750904	DNA topoisomerase I [Paenibacillus sanguinis].	24.72	530	316	19	7	505	6	483	3e-17	95.9
tr:M3GG24_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.57	259	172	8	295	544	2	256	3e-17	92.8
rs:WP_003484458	DNA topoisomerase I [Xanthomonas citri].	23.65	592	350	20	7	563	6	530	3e-17	96.3
rs:WP_010373951	MULTISPECIES: topoisomerase I [Pseudoalteromonas].	22.92	541	336	17	7	505	6	507	3e-17	96.3
rs:WP_020020763	hypothetical protein [alpha proteobacterium SCGC AAA160-J14].	26.28	529	310	21	7	505	4	482	3e-17	96.3
tr:J6PTL9_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJX56890.1}; Flags: Fragment;	32.07	184	116	5	42	223	26	202	3e-17	91.3
rs:WP_042975774	DNA topoisomerase 1 [Bacillus subtilis].	25.09	530	320	19	112	607	82	568	3e-17	95.9
sp:TOP1_BACHD	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.19	528	314	18	7	505	6	481	3e-17	95.9
rs:WP_003141417	DNA topoisomerase I [Pseudomonas aeruginosa].	25.25	499	294	19	86	553	58	508	3e-17	95.9
rs:WP_021973169	DNA topoisomerase [Eubacterium sp. CAG:180].	25.37	540	307	22	7	505	5	489	3e-17	95.9
rs:WP_013910673	DNA topoisomerase I [Corynebacterium ulcerans].	26.11	452	274	17	97	505	86	520	3e-17	96.3
tr:A0A0D6DXL3_9LACT	SubName: Full=DNA topoisomerase 1 TopA {ECO:0000313|EMBL:CEN28525.1};	24.47	523	315	21	7	504	78	545	3e-17	96.3
rs:WP_038316816	DNA topoisomerase I [Kingella kingae].	27.29	447	261	15	107	510	77	502	3e-17	96.3
tr:D7UYI7_LISGR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.54	422	258	14	112	504	93	491	3e-17	95.9
rs:WP_033917814	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	96.3
tr:A0A076LKY0_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	29.41	323	198	11	7	322	5	304	3e-17	96.7
gpu:CP011528_1102	DNA topoisomerase I [Staphylococcus aureus]	25.76	528	309	22	7	505	6	479	3e-17	95.9
rs:WP_018369651	DNA topoisomerase I [Streptococcus marimammalium].	25.90	525	305	22	7	504	19	486	3e-17	95.9
rs:WP_043452439	DNA topoisomerase I [Arthrobacter phenanthrenivorans].	25.68	553	311	21	7	505	12	518	3e-17	96.3
rs:WP_034026384	DNA topoisomerase I [Pseudomonas aeruginosa].	25.25	495	297	18	86	553	58	506	3e-17	95.9
rs:WP_018160535	DNA topoisomerase I [Smaragdicoccus niigatensis].	24.45	589	344	23	7	550	19	551	3e-17	96.3
tr:T0TG73_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.56	517	316	17	10	504	2	466	3e-17	95.9
rs:WP_012810735	DNA topoisomerase I [Alicyclobacillus acidocaldarius].	25.62	527	312	20	7	504	6	481	3e-17	95.9
rs:WP_000024265	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	96.3
rs:WP_032051078	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	96.3
rs:WP_034957424	DNA topoisomerase I [Erythrobacter longus].	26.47	544	300	25	7	510	4	487	3e-17	96.3
rs:WP_040486417	DNA topoisomerase I [Listeria grayi].	26.54	422	258	14	112	504	82	480	3e-17	95.9
gp:CP002906_1692	DNA topoisomerase I [Bacillus subtilis subsp. subtilis str. RO-NN-1]	25.09	530	320	19	112	607	84	570	3e-17	95.9
rs:WP_021479296	DNA topoisomerase 1 [Bacillus sp. EGD-AK10].	25.09	530	320	19	112	607	82	568	3e-17	95.9
rs:WP_022474281	DNA topoisomerase [Ruminococcus sp. CAG:353].	24.38	525	319	21	7	504	5	478	3e-17	95.9
rs:WP_036123967	MULTISPECIES: DNA topoisomerase I [Lysinibacillus].	26.05	430	257	16	109	504	79	481	3e-17	95.9
tr:A0A0A8GV49_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.03	411	265	13	107	500	77	465	3e-17	95.9
tr:U2I1J4_LACPN	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:ERJ61682.1}; Flags: Fragment;	32.13	221	132	7	3	215	2	212	3e-17	91.7
rs:WP_008354502	DNA topoisomerase I [Bacillus xiamenensis].	26.79	418	262	13	112	504	82	480	3e-17	95.9
rs:WP_042144852	DNA topoisomerase I [Paucisalibacillus sp. EB02].	23.76	526	323	19	7	504	6	481	3e-17	95.9
rs:WP_008181277	DNA topoisomerase I [Bacillus sp. B14905].	26.05	430	257	16	109	504	79	481	3e-17	95.9
rs:WP_042930287	DNA topoisomerase I [Pseudomonas aeruginosa].	25.42	476	289	17	99	553	76	506	3e-17	95.9
rs:WP_015902075	DNA topoisomerase I [Nautilia profundicola].	25.90	417	270	13	107	505	78	473	3e-17	95.9
rs:WP_005079182	MULTISPECIES: DNA topoisomerase I [Acinetobacter calcoaceticus/baumannii complex].	23.75	539	324	18	7	505	25	516	3e-17	96.3
rs:WP_004932739	DNA topoisomerase I [Acinetobacter soli].	24.39	537	324	19	7	505	27	519	3e-17	96.3
rs:WP_023123989	DNA topoisomerase I [Pseudomonas aeruginosa].	25.15	501	292	19	86	553	58	508	3e-17	95.9
tr:E3EPR9_BIFBS	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ADO52606.1};	25.96	312	181	9	7	301	5	283	3e-17	93.6
rs:WP_000774792	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	3e-17	95.9
rs:WP_023132186	DNA topoisomerase I [Pseudomonas aeruginosa].	25.35	497	294	19	86	553	58	506	3e-17	95.9
rs:WP_023498024	Topoisomerase IA [uncultured archaeon A07HR67].	21.78	551	337	18	7	498	8	523	3e-17	95.5
rs:WP_034343711	DNA topoisomerase I [Helicobacter typhlonius].	23.39	590	356	18	7	579	5	515	3e-17	95.9
rs:WP_038268974	DNA topoisomerase I [Zhouia amylolytica].	25.34	517	309	17	7	504	6	464	3e-17	95.9
rs:WP_039666460	DNA topoisomerase I [Campylobacter sp. RM16704].	26.03	411	265	13	107	500	78	466	3e-17	95.9
rs:WP_046623771	DNA topoisomerase I [Salmonella enterica].	25.42	539	316	21	7	505	6	498	3e-17	96.3
rs:WP_036248415	DNA topoisomerase I [Methylobacter sp. BBA5.1].	24.96	589	343	20	7	562	6	528	3e-17	95.9
rs:WP_020159280	DNA topoisomerase I [Methylobacter marinus].	24.96	589	343	20	7	562	6	528	3e-17	95.9
rs:WP_003123327	DNA topoisomerase I [Pseudomonas aeruginosa].	25.20	488	275	19	99	553	76	506	3e-17	95.5
rs:WP_034325702	DNA topoisomerase I [Helicobacter sp. MIT 03-1616].	23.39	590	356	18	7	579	5	515	3e-17	95.9
rs:WP_033659063	hypothetical protein [Enterococcus faecium].	32.07	184	116	5	42	223	1	177	3e-17	90.9
rs:WP_033974776	DNA topoisomerase I [Pseudomonas aeruginosa].	24.36	505	289	19	86	553	58	506	3e-17	95.5
rs:WP_002283689	DNA topoisomerase I [Streptococcus mutans].	25.52	525	307	22	7	504	24	491	3e-17	95.9
rs:WP_046736800	DNA topoisomerase I [Dehalogenimonas sp. WBC-2].	25.91	467	285	16	92	516	64	511	3e-17	95.9
rs:WP_040775025	DNA topoisomerase I [Rhodococcus rhodnii].	26.06	591	332	25	7	550	24	556	3e-17	96.3
rs:WP_026585548	DNA topoisomerase I [Bacillus sp. J33].	27.59	424	253	16	112	505	82	481	3e-17	95.9
rs:WP_000024267	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	96.3
rs:WP_031999729	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	96.3
rs:WP_009812653	DNA topoisomerase I [Roseovarius nubinhibens].	24.86	535	316	21	4	505	1	482	3e-17	95.9
rs:WP_029975064	DNA topoisomerase I [Corynebacterium ulcerans].	26.11	452	274	17	97	505	86	520	3e-17	96.3
rs:WP_031838416	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	3e-17	95.9
gp:CP010526_1201	DNA topoisomerase I [Staphylococcus aureus subsp. aureus ST772-MRSA-V]	25.76	528	309	22	7	505	8	481	3e-17	95.9
rs:WP_025649465	DNA topoisomerase I [Bacillus methylotrophicus].	26.37	421	260	14	112	504	82	480	3e-17	95.9
rs:WP_009393140	DNA topoisomerase I [Acinetobacter sp. WC-141].	23.36	535	331	18	7	505	25	516	3e-17	95.9
rs:WP_012606724	DNA topoisomerase I [Acidithiobacillus ferrooxidans].	26.12	425	263	17	107	505	77	476	3e-17	95.9
rs:WP_000024263	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	95.9
rs:WP_000024262	DNA topoisomerase I subunit omega [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	95.9
rs:WP_000024264	topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	95.9
rs:WP_032068885	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	95.9
rs:WP_032035863	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	95.9
rs:WP_035627404	DNA topoisomerase III, partial [Herminiimonas sp. CN].	30.17	242	158	6	5	245	4	235	3e-17	92.0
rs:WP_031368321	hypothetical protein, partial [Clostridium botulinum].	28.81	236	154	7	7	240	5	228	3e-17	92.0
rs:WP_027963176	DNA topoisomerase I [Halalkalibacillus halophilus].	24.57	529	316	17	7	505	6	481	3e-17	95.9
rs:WP_035119821	DNA topoisomerase I [Cohnella panacarvi].	26.48	423	268	13	107	504	77	481	3e-17	95.9
rs:WP_033169858	DNA topoisomerase I [Selenomonas sp. ND2010].	24.67	608	349	27	7	580	25	557	3e-17	95.9
rs:WP_031973291	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	95.9
rs:WP_000024261	topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	95.9
rs:WP_014113782	DNA topoisomerase I [Bacillus subtilis].	27.01	422	256	15	112	504	82	480	3e-17	95.9
rs:WP_023082041	DNA topoisomerase I [Pseudomonas aeruginosa].	25.52	478	286	18	99	553	76	506	3e-17	95.5
rs:WP_004834834	DNA topoisomerase I [Anaerococcus prevotii].	23.71	599	358	23	7	580	6	530	3e-17	95.5
sp:TOP1_BACSU	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.09	530	320	19	112	607	82	568	3e-17	95.9
rs:WP_028708795	DNA topoisomerase I [Propionicicella superfundia].	24.64	552	326	21	7	505	10	524	3e-17	95.9
rs:WP_013325931	DNA topoisomerase I [Sulfurimonas autotrophica].	26.13	421	267	12	107	505	78	476	3e-17	95.9
rs:WP_000024260	topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	95.9
rs:WP_031869532	DNA topoisomerase 1 [Staphylococcus aureus].	25.95	528	308	22	7	505	6	479	3e-17	95.5
rs:WP_031867779	DNA topoisomerase 1 [Staphylococcus aureus].	25.95	528	308	22	7	505	6	479	3e-17	95.5
rs:WP_003690280	DNA topoisomerase I [Lactobacillus mali].	25.19	528	308	21	7	504	19	489	3e-17	95.5
rs:WP_016153252	MULTISPECIES: DNA topoisomerase 1 [Citrobacter].	24.49	535	326	19	7	505	6	498	3e-17	95.9
rs:WP_004748376	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	95.9
tr:J9CNG0_9ZZZZ	SubName: Full=DNA topoisomerase TopB {ECO:0000313|EMBL:EJX01646.1};	22.36	577	363	19	4	550	10	531	3e-17	95.5
rs:WP_023648458	DNA topoisomerase I [Candidatus Pelagibacter ubique].	23.41	534	323	19	7	505	4	486	3e-17	95.9
rs:WP_011219142	topoisomerase I [Photobacterium profundum].	24.44	540	325	19	7	505	6	503	3e-17	95.9
rs:WP_024434017	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	95.9
rs:WP_022730658	DNA topoisomerase I [Thalassospira lucentensis].	25.37	540	314	21	4	505	1	489	3e-17	95.9
rs:WP_031789231	DNA topoisomerase I, partial [Staphylococcus aureus].	25.81	527	308	22	7	504	6	478	3e-17	95.5
rs:WP_025767074	hypothetical protein [Vibrio parahaemolyticus].	23.03	634	367	23	8	547	5	611	3e-17	95.9
rs:WP_022532720	DNA topoisomerase [Methanoculleus sp. CAG:1088].	22.79	544	355	17	4	539	17	503	3e-17	95.9
rs:WP_038621424	DNA topoisomerase I [Corynebacterium ulcerans].	26.11	452	274	17	97	505	86	520	3e-17	95.9
rs:WP_031974178	DNA topoisomerase I [Acinetobacter baumannii].	23.93	539	323	18	7	505	25	516	3e-17	95.9
rs:WP_032095784	MULTISPECIES: DNA topoisomerase I [Alteromonas].	25.09	546	317	20	7	505	6	506	4e-17	95.9
rs:WP_020156269	DNA topoisomerase I [Caldibacillus debilis].	23.92	531	315	18	7	504	6	480	4e-17	95.5
rs:WP_029441257	DNA topoisomerase I [Bacillus mojavensis].	27.01	422	256	15	112	504	82	480	4e-17	95.5
tr:W4LII3_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.57	545	331	20	7	510	6	500	4e-17	95.9
rs:WP_033995540	DNA topoisomerase I [Pseudomonas aeruginosa].	25.10	478	288	17	99	553	76	506	4e-17	95.5
rs:WP_003154274	MULTISPECIES: DNA topoisomerase I [Bacillus subtilis group].	26.37	421	260	14	112	504	82	480	4e-17	95.5
rs:WP_015505040	DNA topoisomerase I [Candidatus Methanomethylophilus alvus].	22.79	544	355	17	4	539	17	503	4e-17	95.9
rs:WP_034240461	DNA topoisomerase I [Actinopolyspora iraqiensis].	25.68	479	284	16	86	510	89	549	4e-17	95.9
rs:WP_005007267	DNA topoisomerase I [Acinetobacter bouvetii].	26.20	439	274	15	88	505	108	517	4e-17	95.9
rs:WP_031770059	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	4e-17	95.5
sp:TOP1_BUCAI	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	22.82	631	397	24	5	607	4	572	4e-17	95.9
rs:WP_011234261	topoisomerase I [Idiomarina loihiensis].	24.72	542	323	22	7	505	6	505	4e-17	95.9
rs:WP_010744647	DNA topoisomerase 1 [Enterococcus raffinosus].	24.34	530	314	19	7	504	7	481	4e-17	95.5
tr:A0A0A8I747_CAMLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.18	409	271	11	107	500	77	465	4e-17	95.5
rs:WP_014027527	DNA topoisomerase I [Acidithiobacillus ferrivorans].	24.08	598	338	21	7	563	6	528	4e-17	95.9
rs:WP_022579620	DNA topoisomerase I [Pseudomonas aeruginosa].	25.52	478	286	18	99	553	76	506	4e-17	95.5
rs:WP_041239714	DNA topoisomerase [Gordonibacter pamelaeae].	22.83	508	343	13	65	562	107	575	4e-17	95.9
rs:WP_003220843	DNA topoisomerase I [Bacillus subtilis].	27.01	422	256	15	112	504	82	480	4e-17	95.5
rs:WP_023478680	DNA topoisomerase I [Enterobacter cloacae].	23.93	535	329	18	7	505	6	498	4e-17	95.9
rs:WP_038407211	DNA topoisomerase I [Listeria ivanovii].	26.73	419	261	14	112	504	82	480	4e-17	95.5
rs:WP_042281596	DNA topoisomerase I [Candidatus Protochlamydia sp. R18].	24.58	594	348	22	7	564	6	535	4e-17	95.9
rs:WP_033849501	DNA topoisomerase I [Acinetobacter baumannii].	23.75	539	324	18	7	505	25	516	4e-17	95.9
rs:WP_013451230	DNA topoisomerase I [Calditerrivibrio nitroreducens].	24.82	560	323	21	7	539	6	494	4e-17	95.9
tr:T0E7I0_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.71	254	158	9	295	543	2	242	4e-17	92.4
rs:WP_039640613	DNA topoisomerase I [Campylobacter lari].	25.18	409	271	11	107	500	78	466	4e-17	95.5
rs:WP_003797825	DNA topoisomerase I [Kingella oralis].	26.40	447	270	14	97	505	67	492	4e-17	95.5
rs:WP_014835855	DNA topoisomerase I [Corynebacterium ulcerans].	26.11	452	274	17	97	505	86	520	4e-17	95.9
rs:WP_041907184	MULTISPECIES: DNA topoisomerase I [Bacillus].	27.01	422	256	15	112	504	82	480	4e-17	95.5
rs:WP_046762942	DNA topoisomerase I [Sphingobium chungbukense].	25.43	523	314	20	7	505	4	474	4e-17	95.9
rs:WP_029061438	DNA topoisomerase I [Labrenzia sp. DG1229].	25.09	562	317	24	4	512	1	511	4e-17	95.9
rs:WP_004920177	MULTISPECIES: topoisomerase I [Acinetobacter].	24.95	537	321	19	7	505	27	519	4e-17	95.9
rs:WP_025052246	DNA topoisomerase I [Sulfitobacter sp. NB-68].	24.86	539	309	23	4	505	1	480	4e-17	95.9
rs:WP_013199013	topoisomerase I [Acinetobacter oleivorans].	23.36	535	331	18	7	505	25	516	4e-17	95.9
rs:WP_034945873	DNA topoisomerase I [Gilliamella apicola].	27.01	448	261	20	88	505	89	500	4e-17	95.9
rs:WP_003238559	DNA topoisomerase I [Bacillus subtilis].	27.01	422	256	15	112	504	82	480	4e-17	95.5
rs:WP_043580749	DNA topoisomerase I [Gemmatimonas sp. AP64].	24.41	549	304	24	8	505	1	489	4e-17	95.5
rs:WP_017391319	topoisomerase I [Acinetobacter calcoaceticus].	23.51	536	329	19	7	505	25	516	4e-17	95.9
rs:WP_014208301	topoisomerase I [Acinetobacter calcoaceticus].	23.61	538	326	18	7	505	25	516	4e-17	95.9
rs:WP_014612281	DNA topoisomerase I [Streptococcus dysgalactiae].	23.61	521	322	16	7	504	29	496	4e-17	95.5
rs:WP_031894812	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	4e-17	95.5
tr:H5SCU4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	571	312	23	7	505	10	530	4e-17	95.9
rs:WP_013358013	MULTISPECIES: topoisomerase I [Pantoea].	25.60	457	294	16	69	505	77	507	4e-17	95.9
tr:W0RPS3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.08	544	322	21	2	505	58	550	4e-17	95.9
rs:WP_019318257	DNA topoisomerase I [Streptococcus mutans].	25.52	525	307	22	7	504	24	491	4e-17	95.5
rs:WP_033936377	DNA topoisomerase I [Pseudomonas aeruginosa].	25.55	497	293	19	86	553	58	506	4e-17	95.5
rs:WP_010189916	DNA topoisomerase I [Corynebacterium aurimucosum].	24.77	541	329	21	5	505	10	512	4e-17	95.9
tr:D0DRB1_LACFE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.24	524	320	20	7	505	27	498	4e-17	95.5
rs:WP_009345264	DNA topoisomerase I [Peptoniphilus sp. oral taxon 836].	24.90	522	320	20	7	504	6	479	4e-17	95.5
rs:WP_039497466	DNA topoisomerase I [Pseudoalteromonas elyakovii].	22.45	539	341	16	7	505	6	507	4e-17	95.9
rs:WP_046347030	DNA topoisomerase I [Sphingomonas changbaiensis].	26.40	519	314	20	7	505	4	474	4e-17	95.9
rs:WP_045246069	DNA topoisomerase I [Microbacterium ginsengisoli].	24.40	545	340	21	43	550	14	523	4e-17	95.9
rs:WP_035111286	DNA topoisomerase I [Corynebacterium freiburgense].	26.01	469	279	18	86	505	78	527	4e-17	95.9
rs:WP_005522405	DNA topoisomerase I [Corynebacterium matruchotii].	24.53	530	307	21	40	505	29	529	4e-17	95.9
rs:WP_008119941	topoisomerase IA, partial [Herbaspirillum sp. YR522].	30.58	242	157	6	3	243	2	233	4e-17	92.0
rs:WP_022468862	DNA topoisomerase [Clostridium sp. CAG:451].	24.96	629	367	24	7	606	6	558	4e-17	95.5
rs:WP_005037005	DNA topoisomerase I [Acinetobacter calcoaceticus].	23.51	536	329	19	7	505	25	516	4e-17	95.9
rs:WP_014525263	DNA topoisomerase I [Corynebacterium ulcerans].	26.11	452	274	17	97	505	86	520	4e-17	95.9
rs:WP_003553968	DNA topoisomerase I [Lactobacillus brevis].	25.26	483	309	18	47	504	44	499	4e-17	95.5
rs:WP_023462771	DNA topoisomerase I [Asticcacaulis sp. YBE204].	26.04	553	307	24	4	510	1	497	4e-17	95.9
rs:WP_023634983	DNA topoisomerase I [Corynebacterium ulcerans].	26.11	452	274	17	97	505	86	520	4e-17	95.9
rs:WP_010735743	DNA topoisomerase 1 [Enterococcus mundtii].	25.00	524	318	20	7	504	7	481	4e-17	95.5
rs:WP_026704084	DNA topoisomerase I [Flavobacterium soli].	26.47	529	287	26	7	504	6	463	4e-17	95.5
rs:WP_023839464	DNA topoisomerase I [Blastomonas sp. CACIA14H2].	26.29	525	307	22	7	505	4	474	4e-17	95.5
rs:WP_010547138	topoisomerase I [gamma proteobacterium HIMB30].	23.95	547	330	18	7	512	6	507	4e-17	95.5
rs:WP_014092677	DNA topoisomerase I [Listeria ivanovii].	26.73	419	261	14	112	504	82	480	4e-17	95.5
rs:WP_017390083	topoisomerase I [Acinetobacter calcoaceticus].	23.51	536	329	19	7	505	25	516	4e-17	95.5
rs:WP_034802148	DNA topoisomerase I [Eubacterium sp. AB3007].	26.58	444	273	14	105	517	78	499	4e-17	95.5
rs:WP_000774786	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	4e-17	95.5
rs:WP_046306847	DNA topoisomerase I [Lactobacillus apis].	23.95	522	328	17	5	505	13	486	4e-17	95.5
rs:WP_003654752	topoisomerase I [Acinetobacter calcoaceticus].	23.51	536	329	19	7	505	25	516	4e-17	95.5
rs:WP_047172476	DNA topoisomerase I [Staphylococcus xylosus].	25.19	528	309	19	7	504	6	477	4e-17	95.5
rs:WP_000774785	DNA topoisomerase 1 [Staphylococcus aureus].	25.19	528	312	21	7	505	6	479	4e-17	95.5
rs:WP_037558001	DNA topoisomerase I [Staphylococcus haemolyticus].	24.43	528	314	18	7	504	6	478	4e-17	95.5
rs:WP_028646671	DNA topoisomerase I [Nocardiopsis sp. CNT312].	24.91	550	324	20	7	505	26	537	4e-17	95.9
rs:WP_010768602	DNA topoisomerase 1 [Enterococcus phoeniculicola].	24.62	532	322	19	1	504	1	481	4e-17	95.5
rs:WP_031693912	DNA topoisomerase I [Pseudomonas aeruginosa].	25.15	497	295	19	86	553	58	506	4e-17	95.1
rs:WP_000774778	DNA topoisomerase I [Staphylococcus aureus].	25.19	528	312	21	7	505	6	479	4e-17	95.5
rs:WP_046327098	DNA topoisomerase I [Lactobacillus helsingborgensis].	23.71	523	324	17	7	505	15	486	4e-17	95.5
rs:WP_038617458	DNA topoisomerase I [Corynebacterium ulcerans].	26.11	452	274	17	97	505	86	520	4e-17	95.9
rs:WP_026172433	hypothetical protein, partial [euryarchaeote SCGC AAA261-G15].	23.13	549	334	18	7	532	1	484	4e-17	95.1
rs:WP_046474260	DNA topoisomerase I [marine gamma proteobacterium ASP10-03a].	23.98	442	289	13	88	505	98	516	4e-17	95.5
rs:WP_025080665	DNA topoisomerase I [Lactobacillus hamsteri].	23.63	529	317	18	7	505	19	490	4e-17	95.5
rs:WP_039457938	DNA topoisomerase I [Thermus sp. 2.9].	24.54	542	319	22	2	505	16	505	4e-17	95.5
rs:WP_023004052	MULTISPECIES: DNA topoisomerase I [Labrenzia].	26.01	569	303	27	4	512	1	511	4e-17	95.5
sp:TOP1_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.76	528	309	22	7	505	6	479	4e-17	95.1
tr:M1NV36_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.43	468	284	17	86	505	63	513	4e-17	95.9
rs:WP_033790335	DNA topoisomerase I [Pantoea sp. FF5].	26.54	456	291	16	69	505	68	498	4e-17	95.5
rs:WP_012391203	DNA topoisomerase I [Lactobacillus fermentum].	24.67	523	317	21	7	504	29	499	4e-17	95.5
rs:WP_014562385	DNA topoisomerase I [Lactobacillus fermentum].	24.67	523	317	21	7	504	29	499	4e-17	95.5
rs:WP_027004206	DNA topoisomerase I [Corynebacterium halotolerans].	25.43	468	284	17	86	505	77	527	5e-17	95.5
gp:CP001996_1224	DNA topoisomerase I [Staphylococcus aureus subsp. aureus ED133]	25.76	528	309	22	7	505	8	481	5e-17	95.1
rs:WP_010759374	DNA topoisomerase 1 [Enterococcus pallens].	24.33	526	319	18	7	504	7	481	5e-17	95.1
rs:WP_016139347	DNA topoisomerase I [Acinetobacter calcoaceticus].	23.51	536	329	19	7	505	25	516	5e-17	95.5
rs:WP_004641017	DNA topoisomerase I [Acinetobacter calcoaceticus].	23.51	536	329	19	7	505	25	516	5e-17	95.5
rs:WP_024843173	DNA topoisomerase I [Paracoccus pantotrophus].	25.14	537	309	21	4	505	1	479	5e-17	95.5
gp:CP010941_1149	DNA topoisomerase I [Staphylococcus aureus]	25.76	528	309	22	7	505	6	479	5e-17	95.1
rs:WP_045336485	DNA topoisomerase I [Enterobacter cloacae].	25.23	535	322	20	7	505	6	498	5e-17	95.5
rs:WP_044141928	DNA topoisomerase I [Bacillus pumilus].	26.60	421	259	14	112	504	82	480	5e-17	95.1
rs:WP_039355843	DNA topoisomerase I [Candidatus Protochlamydia amoebophila].	24.58	594	348	22	7	564	6	535	5e-17	95.5
rs:WP_017671279	DNA topoisomerase I [Blastomonas sp. AAP53].	26.48	525	306	22	7	505	4	474	5e-17	95.5
rs:WP_013266347	DNA topoisomerase III [Acidilobus saccharovorans].	23.30	631	389	27	7	602	16	586	5e-17	95.1
rs:WP_014976305	topoisomerase I [Alteromonas macleodii].	25.99	431	278	14	93	505	99	506	5e-17	95.5
rs:WP_009795914	MULTISPECIES: DNA topoisomerase I [Bacillus].	26.37	421	262	15	112	505	82	481	5e-17	95.1
tr:B0VL89_ACIBS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.63	540	318	20	7	505	25	516	5e-17	95.5
rs:WP_042843673	DNA topoisomerase I [Providencia rettgeri].	26.53	441	272	17	88	505	90	501	5e-17	95.5
rs:WP_036593777	DNA topoisomerase I, partial [Paenibacillus sophorae].	25.60	418	267	15	107	505	127	519	5e-17	95.5
rs:WP_017384217	MULTISPECIES: topoisomerase I [Enterobacter cloacae complex].	25.23	535	322	20	7	505	6	498	5e-17	95.5
rs:WP_044155905	DNA topoisomerase I [Salinibacillus aidingensis].	27.01	422	256	15	112	504	82	480	5e-17	95.1
rs:WP_042894703	DNA topoisomerase I [Acinetobacter oleivorans].	23.89	540	322	19	7	505	25	516	5e-17	95.5
sp:TOP1_STAS1	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.00	524	315	19	7	504	6	477	5e-17	95.1
rs:WP_039270612	DNA topoisomerase I [Enterobacter cloacae].	25.23	535	322	20	7	505	6	498	5e-17	95.5
tr:I0DNS9_PROSM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.32	437	278	14	88	505	20	431	5e-17	95.5
rs:WP_003856806	MULTISPECIES: topoisomerase I [Enterobacter cloacae complex].	25.23	535	322	20	7	505	6	498	5e-17	95.5
rs:WP_031552739	DNA topoisomerase I [Parvularcula oceani].	23.35	651	365	27	4	607	1	564	5e-17	95.5
rs:WP_016192569	DNA topoisomerase I subunit omega [Erwinia tracheiphila].	25.66	456	295	14	69	505	68	498	5e-17	95.5
rs:WP_023102572	DNA topoisomerase I [Pseudomonas aeruginosa].	24.95	497	296	19	86	553	58	506	5e-17	95.1
rs:WP_027974779	DNA topoisomerase I [Streptococcus porci].	25.14	521	313	19	7	504	25	491	5e-17	95.1
rs:WP_031826017	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	5e-17	95.1
rs:WP_045345096	DNA topoisomerase I [Enterobacter cloacae].	25.23	535	322	20	7	505	6	498	5e-17	95.5
rs:WP_006175684	topoisomerase I [Enterobacter cancerogenus].	24.86	531	329	19	7	505	6	498	5e-17	95.5
rs:WP_034072159	DNA topoisomerase I [Pseudomonas aeruginosa].	24.95	497	296	19	86	553	58	506	5e-17	95.1
rs:WP_046693466	DNA topoisomerase I [Corynebacterium ulcerans].	26.11	452	274	17	97	505	86	520	5e-17	95.5
rs:WP_045341511	DNA topoisomerase I [Enterobacter cloacae].	25.23	535	322	20	7	505	6	498	5e-17	95.5
rs:WP_038041729	hypothetical protein, partial [Thermodesulfobacterium hveragerdense].	25.88	568	328	25	7	558	6	496	5e-17	94.7
rs:WP_025113925	DNA topoisomerase I [Lysinibacillus fusiformis].	26.05	430	257	16	109	504	79	481	5e-17	95.1
rs:WP_045071992	DNA topoisomerase I [Chlamydophila abortus].	23.70	595	350	23	7	563	6	534	5e-17	95.5
rs:WP_016504476	DNA topoisomerase III, partial [Pasteurella multocida].	27.23	235	158	6	8	238	5	230	5e-17	91.7
rs:WP_040537360	DNA topoisomerase [Lactobacillus pasteurii].	24.60	435	288	17	7	424	5	416	5e-17	95.1
rs:WP_005357832	DNA topoisomerase I [[Eubacterium] siraeum].	23.77	530	320	18	7	505	19	495	5e-17	95.1
rs:WP_044023756	DNA topoisomerase I, partial [Bacillus cereus].	24.90	526	318	20	7	505	6	481	5e-17	94.7
tr:T0TYN3_9STRE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.12	425	258	15	107	504	20	415	5e-17	95.1
rs:WP_023101907	DNA topoisomerase I [Pseudomonas aeruginosa].	25.25	495	297	19	86	553	58	506	5e-17	95.1
rs:WP_004920164	topoisomerase I [Providencia stuartii].	26.32	437	278	14	88	505	86	497	5e-17	95.5
rs:WP_035423519	DNA topoisomerase I [Lactobacillus fermentum].	24.24	524	320	20	7	505	29	500	5e-17	95.1
rs:WP_004326356	MULTISPECIES: DNA topoisomerase III [Bacteroides].	21.63	564	357	20	4	536	1	510	5e-17	94.7
rs:WP_031824418	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	5e-17	95.1
rs:WP_044172924	DNA topoisomerase I, partial [Oscillatoria sp. PCC 10802].	24.13	460	299	16	91	520	65	504	5e-17	94.7
rs:WP_040469686	DNA topoisomerase I [Lactobacillus ingluviei].	25.43	527	308	23	7	504	26	496	5e-17	95.1
tr:A0A090VZF4_9FLAO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL68624.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL68624.1};	30.09	226	145	6	8	231	5	219	5e-17	91.3
rs:WP_005935543	DNA topoisomerase I [Faecalibacterium prausnitzii].	25.99	531	308	21	7	505	5	482	5e-17	95.1
rs:WP_019034424	DNA topoisomerase I [Peptoniphilus lacrimalis].	25.29	522	318	19	7	504	6	479	5e-17	95.1
rs:WP_031903339	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	5e-17	95.1
rs:WP_036940356	DNA topoisomerase I [Providencia stuartii].	26.32	437	278	14	88	505	86	497	5e-17	95.5
rs:WP_044142794	DNA topoisomerase I [Anaplasma phagocytophilum].	25.38	532	320	21	4	504	1	486	5e-17	95.5
rs:WP_036767626	DNA topoisomerase I, partial [Peptostreptococcaceae bacterium VA2].	25.42	598	356	22	5	579	4	534	5e-17	95.1
rs:WP_009874238	topoisomerase I [Buchnera aphidicola].	22.82	631	397	24	5	607	4	572	5e-17	95.5
rs:WP_033861012	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	5e-17	95.1
rs:WP_029563674	DNA topoisomerase I [alpha proteobacterium SCGC AAA240-E13].	23.78	534	327	21	4	505	1	486	5e-17	95.5
rs:WP_041704980	DNA topoisomerase I [Providencia stuartii].	26.32	437	278	14	88	505	17	428	5e-17	95.1
tr:T0RV12_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.92	577	338	20	7	544	58	572	5e-17	95.5
rs:WP_004668544	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	26.76	441	269	16	88	505	108	517	5e-17	95.5
rs:WP_012716149	DNA topoisomerase I [Sulfolobus islandicus].	22.78	540	342	18	42	564	53	534	5e-17	95.1
rs:WP_022272018	DNA topoisomerase [Eubacterium siraeum CAG:80].	23.66	524	328	17	7	505	5	481	5e-17	95.1
rs:WP_003134111	DNA topoisomerase I [Pseudomonas aeruginosa].	25.35	497	294	19	86	553	58	506	5e-17	95.1
rs:WP_024460340	DNA topoisomerase I [Marinimicrobium sp. LS-A18].	24.45	454	303	14	69	505	79	509	5e-17	95.5
rs:WP_034923839	DNA topoisomerase I [Erysipelotrichaceae bacterium NK3D112].	24.44	536	332	23	97	603	69	560	5e-17	95.1
tr:A0A077TXL4_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.24	527	311	21	7	504	8	480	5e-17	95.1
tr:A0A009FW92_ACIBA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	537	328	17	7	505	2	494	5e-17	95.5
rs:WP_010259203	DNA topoisomerase I [Treponema primitia].	27.75	436	243	21	107	504	87	488	5e-17	95.1
rs:WP_038471906	DNA topoisomerase I [Cedecea neteri].	24.84	459	305	13	64	505	63	498	5e-17	95.5
rs:WP_000513606	hypothetical protein, partial [Escherichia coli].	24.81	536	321	21	7	504	6	497	5e-17	94.7
rs:WP_005232311	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	23.65	537	328	17	7	505	26	518	5e-17	95.5
rs:WP_003683147	DNA topoisomerase I [Lactobacillus fermentum].	24.67	523	317	21	7	504	29	499	5e-17	95.1
rs:WP_003797809	DNA topoisomerase I [Arthrobacter globiformis].	26.26	556	304	24	7	505	12	518	5e-17	95.5
tr:W8UYB5_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.76	528	309	22	7	505	8	481	5e-17	95.1
rs:WP_046948315	DNA topoisomerase I [Lactobacillus fermentum].	24.67	523	317	21	7	504	27	497	5e-17	95.1
tr:H3KHJ1_9BURK	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.63	234	152	6	306	531	5	231	5e-17	94.7
rs:WP_010114390	topoisomerase I [Acinetobacter sp. P8-3-8].	24.21	537	325	17	7	505	27	519	5e-17	95.5
rs:WP_033866760	DNA topoisomerase I [Pseudomonas aeruginosa].	24.95	497	296	19	86	553	58	506	5e-17	94.7
rs:WP_039031854	DNA topoisomerase I [Leclercia adecarboxylata].	24.34	534	327	19	7	505	6	497	5e-17	95.5
rs:WP_005605437	DNA topoisomerase I [Granulicatella adiacens].	24.42	520	324	18	7	504	7	479	5e-17	95.1
tr:A0A0A8HDI3_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.18	409	271	11	107	500	77	465	5e-17	94.7
rs:WP_002270391	DNA topoisomerase I [Streptococcus mutans].	25.52	525	307	22	7	504	24	491	5e-17	95.1
rs:WP_000774783	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	5e-17	95.1
rs:WP_000774782	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	5e-17	95.1
sp:TOP1_STAAM	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.76	528	309	22	7	505	6	479	5e-17	95.1
rs:WP_013597664	DNA topoisomerase I [Weeksella virosa].	27.11	450	270	18	80	504	48	464	5e-17	95.1
rs:WP_025095361	DNA topoisomerase I [Acinetobacter soli].	24.11	535	328	16	7	505	27	519	5e-17	95.5
rs:WP_031637565	DNA topoisomerase I [Pseudomonas aeruginosa].	24.36	505	289	19	86	553	58	506	6e-17	94.7
rs:WP_031807729	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	6e-17	95.1
rs:WP_034821739	DNA topoisomerase I [[Eubacterium] nodatum].	26.88	532	298	23	5	505	7	478	6e-17	95.1
rs:WP_039426347	DNA topoisomerase I, partial [Porphyromonas gulae].	29.86	221	125	8	172	389	2	195	6e-17	90.5
rs:WP_014639162	topoisomerase I [Escherichia coli].	24.44	540	320	20	7	505	6	498	6e-17	95.1
rs:WP_015808006	DNA topoisomerase I [Pedobacter heparinus].	25.56	450	262	14	89	505	59	468	6e-17	95.1
rs:WP_012980200	DNA topoisomerase I [Methanocaldococcus sp. FS406-22].	29.41	323	198	11	7	322	5	304	6e-17	95.5
rs:WP_005044934	DNA topoisomerase I [Acinetobacter calcoaceticus].	23.80	521	321	18	7	495	25	501	6e-17	95.1
rs:WP_034169866	DNA topoisomerase I [Acinetobacter sp. YZS-X1-1].	23.65	537	328	17	7	505	26	518	6e-17	95.1
rs:WP_033945040	DNA topoisomerase I [Pseudomonas aeruginosa].	25.42	476	289	17	99	553	76	506	6e-17	94.7
rs:WP_046095456	DNA topoisomerase I [Corynebacterium ulcerans].	26.11	452	274	17	97	505	86	520	6e-17	95.5
rs:WP_016103249	DNA topoisomerase 3 [Bacillus cereus].	29.27	205	127	6	5	207	4	192	6e-17	90.5
tr:A0A0C2LFM7_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.76	528	309	22	7	505	8	481	6e-17	95.1
rs:WP_045928058	DNA topoisomerase I [Lactobacillus kullabergensis].	23.71	523	324	17	7	505	15	486	6e-17	95.1
rs:WP_031865838	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	6e-17	95.1
tr:W8YLE3_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.36	440	267	15	98	505	33	447	6e-17	94.7
rs:WP_029418511	DNA topoisomerase I [Bacillus sonorensis].	25.84	418	266	13	112	504	82	480	6e-17	95.1
rs:WP_002355040	toprim domain protein, partial [Enterococcus faecium].	31.52	184	117	5	42	223	26	202	6e-17	90.5
gpu:CP010423_1540	DNA topoisomerase I [Pragia fontium]	24.67	531	325	22	7	505	6	493	6e-17	95.1
rs:WP_034303372	DNA topoisomerase I [Alkalibacterium sp. AK22].	24.48	527	316	18	7	505	7	479	6e-17	95.1
tr:J6NN72_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJX43865.1}; Flags: Fragment;	32.74	226	135	8	5	223	3	218	6e-17	90.9
rs:WP_005095508	DNA topoisomerase I [Acinetobacter lwoffii].	25.51	439	277	14	88	505	109	518	6e-17	95.1
rs:WP_000774781	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	6e-17	95.1
rs:WP_034533897	DNA topoisomerase I [Lactobacillus kunkeei].	24.52	526	316	19	7	505	21	492	6e-17	95.1
rs:WP_031421645	DNA topoisomerase I [Exiguobacterium sp. NG55].	23.97	630	371	23	7	599	6	564	6e-17	95.1
rs:WP_041046419	DNA topoisomerase I [Wolbachia endosymbiont of Cimex lectularius].	25.05	463	287	15	80	504	46	486	6e-17	95.1
rs:XP_007011462	DNA topoisomerase isoform 1 [Theobroma cacao].	25.97	516	298	19	47	505	221	709	6e-17	95.5
rs:WP_006638185	DNA topoisomerase I [Bacillus sonorensis].	25.84	418	266	13	112	504	82	480	6e-17	94.7
rs:WP_023875927	DNA topoisomerase I [Pseudomonas aeruginosa].	25.25	495	297	18	86	553	58	506	6e-17	94.7
rs:WP_000774779	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	6e-17	94.7
rs:WP_011959681	topoisomerase I [Psychrobacter sp. PRwf-1].	24.49	535	329	22	7	505	23	518	6e-17	95.1
rs:WP_039425451	DNA topoisomerase I [Vibrio navarrensis].	23.79	454	305	13	69	505	74	503	6e-17	95.1
rs:WP_023466136	DNA topoisomerase I [Lactobacillus fermentum].	24.67	523	317	21	7	504	29	499	6e-17	95.1
rs:WP_031895351	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	6e-17	94.7
tr:X1LU46_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C00382 {ECO:0000313|EMBL:GAH97648.1}; Flags: Fragment;	28.49	351	203	16	201	539	3	317	6e-17	94.4
rs:WP_021799565	DNA topoisomerase I [Anaplasma phagocytophilum].	25.38	532	320	21	4	504	1	486	6e-17	95.1
tr:V1CS44_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.75	522	322	17	7	505	35	503	6e-17	95.1
tr:R7WHZ6_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.06	591	332	25	7	550	1	533	6e-17	95.1
rs:WP_002719330	DNA topoisomerase I [Rhodobacter sphaeroides].	25.32	545	317	24	4	510	1	493	6e-17	95.1
rs:WP_020975460	DNA topoisomerase I [Corynebacterium argentoratense].	26.26	476	284	18	80	505	68	526	6e-17	95.1
rs:WP_019638089	DNA topoisomerase I [Paenibacillus fonticola].	24.39	529	318	20	7	505	6	482	6e-17	94.7
rs:WP_027506713	DNA topoisomerase I [Rhodococcus sp. UNC23MFCrub1.1].	25.00	588	342	22	7	550	21	553	6e-17	95.1
rs:WP_034905489	DNA topoisomerase I [Campylobacter sp. MIT 97-5078].	23.97	438	289	13	89	504	59	474	6e-17	94.7
rs:WP_027263490	DNA topoisomerase I [Sedimentitalea nanhaiensis].	24.86	547	317	23	4	510	1	493	6e-17	95.1
rs:WP_028372589	DNA topoisomerase I [Legionella lansingensis].	26.35	539	306	20	7	505	6	493	6e-17	95.1
rs:WP_007988003	MULTISPECIES: DNA topoisomerase I [Glaciecola].	24.68	539	328	19	7	505	6	506	6e-17	95.1
rs:WP_005220842	DNA topoisomerase I [Acinetobacter sp. CIP 101934].	23.84	537	327	18	7	505	26	518	6e-17	95.1
rs:XP_007011463	DNA topoisomerase isoform 2 [Theobroma cacao].	25.97	516	298	19	47	505	297	785	6e-17	95.5
rs:WP_000774787	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	6e-17	94.7
rs:WP_038335130	DNA topoisomerase I [Kingella kingae].	26.83	451	266	15	103	510	73	502	6e-17	95.1
rs:XP_004291220	PREDICTED: uncharacterized protein LOC101314719 isoform X1 [Fragaria vesca subsp. vesca].	26.49	521	289	21	47	505	444	932	6e-17	95.5
tr:T0TU76_LACFE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.67	523	317	21	7	504	29	499	6e-17	94.7
rs:WP_015705739	topoisomerase I [Enterobacter aerogenes].	25.14	537	320	20	7	505	6	498	6e-17	95.1
rs:WP_036751414	DNA topoisomerase I [Paracoccus versutus].	24.77	537	311	21	4	505	1	479	6e-17	95.1
rs:WP_034727506	hypothetical protein, partial [Bacteriovorax sp. BSW11_IV].	23.92	577	338	20	7	544	71	585	6e-17	95.1
rs:XP_007011466	DNA topoisomerase isoform 5 [Theobroma cacao].	26.06	518	295	20	47	505	388	876	6e-17	95.1
rs:WP_034030652	DNA topoisomerase I [Pseudomonas aeruginosa].	25.05	495	298	19	86	553	58	506	6e-17	94.7
rs:WP_033868999	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	6e-17	94.7
rs:WP_047247320	DNA topoisomerase I [Maribacter thermophilus].	24.90	518	311	17	7	504	6	465	6e-17	95.1
rs:WP_046025708	DNA topoisomerase I [Lactobacillus fermentum].	24.67	523	317	21	7	504	29	499	6e-17	94.7
rs:WP_031788381	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	6e-17	94.7
rs:WP_015827822	DNA topoisomerase I [Hirschia baltica].	25.87	549	318	23	4	515	1	497	6e-17	95.1
rs:WP_022423366	DNA topoisomerase [Clostridium sp. CAG:440].	24.91	538	301	23	7	504	6	480	6e-17	94.7
tr:E6MFE6_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.58	430	279	15	93	504	62	468	6e-17	94.7
rs:WP_045434910	DNA topoisomerase I [Acinetobacter calcoaceticus].	23.51	536	329	19	7	505	25	516	6e-17	95.1
rs:WP_023110927	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	25.25	499	294	19	86	553	58	508	6e-17	94.4
rs:WP_036888715	DNA topoisomerase I [Porphyromonas crevioricanis].	24.47	523	311	17	7	504	6	469	6e-17	95.1
rs:WP_012717494	DNA topoisomerase I [Sulfolobus islandicus].	22.72	581	368	20	7	564	12	534	6e-17	94.7
rs:WP_021689324	DNA topoisomerase I [Novosphingobium tardaugens].	26.78	534	294	24	7	505	4	475	6e-17	95.1
rs:WP_041654938	DNA topoisomerase I [Arcobacter sp. L].	24.87	599	332	25	7	568	5	522	6e-17	95.1
rs:WP_009222995	DNA topoisomerase I [Paenibacillus sp. oral taxon 786].	24.24	528	321	18	7	505	6	483	6e-17	94.7
rs:WP_047186038	DNA topoisomerase I [Bacilli bacterium VT-13-104].	24.62	528	317	20	7	505	6	481	6e-17	94.7
rs:WP_032044815	DNA topoisomerase I [Acinetobacter baumannii].	23.75	539	324	18	7	505	25	516	6e-17	95.1
rs:WP_005899117	DNA topoisomerase I subunit omega [Aeromonas molluscorum].	22.57	536	338	17	7	505	6	501	6e-17	95.1
rs:WP_004993992	DNA topoisomerase I [Acinetobacter ursingii].	24.49	535	326	20	7	505	27	519	7e-17	95.1
rs:WP_035427363	DNA topoisomerase I [Lactobacillus fermentum].	24.67	523	317	21	7	504	27	497	7e-17	94.7
rs:WP_013753682	topoisomerase I [Glaciecola sp. 4H-3-7+YE-5].	24.68	539	328	19	7	505	6	506	7e-17	95.1
rs:WP_031418983	DNA topoisomerase I [Lysinibacillus sphaericus].	26.05	430	257	16	109	504	79	481	7e-17	94.7
rs:WP_000774784	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	7e-17	94.7
rs:WP_009562909	DNA topoisomerase I [Rhodobacter sp. AKP1].	25.32	545	317	24	4	510	1	493	7e-17	95.1
rs:WP_000320658	hypothetical protein, partial [Vibrio cholerae].	30.49	164	110	1	380	539	1	164	7e-17	91.3
rs:WP_040639880	DNA topoisomerase I [Pseudoramibacter alactolyticus].	25.58	430	279	15	93	504	63	469	7e-17	94.7
rs:WP_046434318	DNA topoisomerase I [Ruminococcus sp. UNK.MGS-30].	24.52	526	323	17	7	505	5	483	7e-17	94.7
rs:WP_046414027	DNA topoisomerase I [Ruminococcus sp. A254.MGS-254].	24.29	638	375	27	7	605	5	573	7e-17	94.7
rs:WP_035428782	DNA topoisomerase I [Lactobacillus fermentum].	24.67	523	317	21	7	504	29	499	7e-17	94.7
rs:WP_044195038	DNA topoisomerase I [Ehrlichia sp. HF].	25.73	548	318	22	4	510	1	500	7e-17	95.1
tr:W1F1E9_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.77	537	322	21	7	505	6	498	7e-17	94.4
tr:H4J7F7_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.77	537	322	21	7	505	6	498	7e-17	94.4
rs:WP_012542049	topoisomerase I [Klebsiella pneumoniae].	24.11	535	328	19	7	505	6	498	7e-17	95.1
rs:WP_030524188	DNA topoisomerase I [Nocardia rhamnosiphila].	24.70	591	344	21	7	550	19	555	7e-17	95.1
rs:WP_034038751	DNA topoisomerase I [Pseudomonas aeruginosa].	25.15	497	295	19	86	553	58	506	7e-17	94.7
rs:WP_036651426	DNA topoisomerase I [Paenibacillus pini].	24.34	534	310	22	7	504	6	481	7e-17	94.7
rs:WP_022468181	DNA topoisomerase [Acidaminococcus sp. CAG:917].	24.53	587	343	23	7	564	5	520	7e-17	94.7
rs:WP_046811441	DNA topoisomerase I [Acinetobacter pittii].	23.56	539	325	18	7	505	25	516	7e-17	95.1
rs:WP_006907650	DNA topoisomerase I [Facklamia hominis].	24.09	523	320	21	7	505	7	476	7e-17	94.7
rs:WP_002478284	DNA topoisomerase I [Staphylococcus lugdunensis].	26.85	432	252	16	107	504	77	478	7e-17	94.7
rs:WP_031906744	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	7e-17	94.7
rs:WP_004991376	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	24.49	535	326	20	7	505	27	519	7e-17	95.1
rs:WP_037592149	DNA topoisomerase I [Streptococcus hongkongensis].	23.72	527	314	17	7	504	29	496	7e-17	94.7
rs:WP_012658424	DNA topoisomerase I [Streptococcus uberis].	23.72	527	314	17	7	504	29	496	7e-17	94.7
rs:WP_031914685	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	7e-17	94.7
rs:WP_000513600	topoisomerase I [Escherichia fergusonii].	25.11	466	295	16	64	505	63	498	7e-17	95.1
rs:WP_025027668	DNA topoisomerase I [Bacillus mannanilyticus].	25.96	443	275	16	92	504	61	480	7e-17	94.7
rs:WP_031649808	DNA topoisomerase III, partial [Listeria innocua].	28.05	221	137	6	5	221	4	206	7e-17	90.5
tr:L7NK28_PHODP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.60	461	288	17	69	505	75	504	7e-17	95.1
sp:TOP1_STAHJ	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.43	528	314	18	7	504	6	478	7e-17	94.7
rs:WP_012765531	MULTISPECIES: topoisomerase I [Dickeya].	24.51	457	298	14	69	505	72	501	7e-17	95.1
rs:WP_029749639	DNA topoisomerase, partial [Streptococcus agalactiae].	29.88	251	132	9	307	539	2	226	7e-17	91.7
rs:WP_004561483	DNA topoisomerase I [Lactobacillus hilgardii].	25.26	483	309	18	47	504	44	499	7e-17	94.7
tr:W6TY68_9SPHI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.48	353	209	11	91	431	61	378	7e-17	93.2
rs:WP_036983237	DNA topoisomerase I [Providencia alcalifaciens].	25.51	443	271	16	91	505	58	469	7e-17	94.7
rs:WP_014281069	DNA topoisomerase I [Paenibacillus terrae].	25.00	528	314	20	7	504	6	481	7e-17	94.7
rs:WP_014643263	DNA topoisomerase I [Halobacillus halophilus].	27.79	421	256	15	112	505	82	481	7e-17	94.7
rs:WP_003747402	DNA topoisomerase I [Listeria seeligeri].	26.49	419	262	14	112	504	82	480	7e-17	94.7
rs:WP_012985514	DNA topoisomerase I [Listeria seeligeri].	26.49	419	262	14	112	504	82	480	7e-17	94.7
rs:WP_033746803	DNA topoisomerase I [Pantoea sp. NGS-ED-1003].	26.54	456	291	16	69	505	68	498	7e-17	94.7
rs:WP_005001350	DNA topoisomerase I [Acinetobacter ursingii].	24.20	533	330	19	7	505	27	519	7e-17	94.7
rs:WP_044175323	DNA topoisomerase I [Photobacterium damselae].	25.81	461	287	17	69	505	75	504	7e-17	94.7
rs:WP_011640264	DNA topoisomerase I [Syntrophomonas wolfei].	25.78	547	299	23	1	505	1	482	7e-17	94.7
rs:WP_031765830	DNA topoisomerase 1 [Staphylococcus aureus].	25.57	528	310	22	7	505	6	479	7e-17	94.7
rs:WP_041152313	DNA topoisomerase I [Lactobacillus kunkeei].	24.52	526	316	19	7	505	21	492	7e-17	94.7
rs:WP_032070408	DNA topoisomerase I [Acinetobacter baumannii].	23.56	539	325	18	7	505	25	516	7e-17	94.7
rs:XP_007011465	DNA topoisomerase isoform 4 [Theobroma cacao].	26.06	518	295	20	47	505	346	834	7e-17	95.1
rs:WP_002459295	DNA topoisomerase I [Staphylococcus lugdunensis].	25.38	532	304	21	7	504	6	478	7e-17	94.7
rs:WP_026541356	DNA topoisomerase I [Arthrobacter nicotinovorans].	25.05	547	322	19	7	505	12	518	7e-17	95.1
rs:WP_014464133	DNA topoisomerase I [Alicyclobacillus acidocaldarius].	25.14	533	307	21	7	504	6	481	7e-17	94.7
sp:TOP1_THEMA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.23	551	323	20	7	544	9	483	7e-17	94.4
rs:WP_031773420	DNA topoisomerase I [Pseudomonas aeruginosa].	25.15	497	295	19	86	553	58	506	7e-17	94.4
rs:WP_023105002	DNA topoisomerase I [Pseudomonas aeruginosa].	25.31	478	287	18	99	553	76	506	7e-17	94.4
rs:WP_033244489	MULTISPECIES: DNA topoisomerase I, partial [Actinomycetales].	25.04	591	342	21	7	550	19	555	7e-17	95.1
rs:WP_023628782	DNA topoisomerase I [Pseudomonas mosselii].	25.32	474	295	15	97	553	75	506	7e-17	94.4
rs:WP_034317776	DNA topoisomerase I [Bacillus sp. DW5-4].	26.60	421	259	14	112	504	82	480	7e-17	94.7
rs:WP_008193802	MULTISPECIES: DNA topoisomerase I [Thermotoga].	25.23	551	323	20	7	544	9	483	8e-17	94.4
rs:WP_008930828	DNA topoisomerase I [Ectothiorhodospira sp. PHS-1].	24.21	541	316	17	7	505	6	494	8e-17	94.7
rs:XP_007011464	DNA topoisomerase isoform 3 [Theobroma cacao].	26.06	518	295	20	47	505	346	834	8e-17	95.1
rs:WP_011979781	DNA topoisomerase I [Sulfurovum sp. NBC37-1].	26.15	436	268	15	97	505	69	477	8e-17	94.7
rs:WP_013961209	DNA topoisomerase I [Roseobacter litoralis].	25.05	547	317	22	4	510	1	494	8e-17	94.7
rs:WP_035240901	DNA topoisomerase I [Desulfobacter vibrioformis].	26.25	461	277	18	93	515	63	498	8e-17	94.7
rs:WP_010236162	DNA topoisomerase I [Clostridium arbusti].	25.43	527	312	21	7	504	6	480	8e-17	94.7
rs:WP_031790580	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	8e-17	94.7
rs:WP_044857889	DNA topoisomerase I, partial [Enterobacter cloacae].	24.49	535	326	19	7	505	6	498	8e-17	94.0
rs:WP_011858247	DNA topoisomerase I [Acinetobacter baumannii].	25.57	442	273	15	88	505	17	426	8e-17	94.7
rs:WP_007001207	DNA topoisomerase I [Actinobaculum massiliense].	24.23	553	328	18	5	505	3	516	8e-17	94.7
rs:WP_040463505	DNA topoisomerase I [Helicobacter bilis].	26.14	440	273	15	109	515	75	495	8e-17	94.7
tr:G8PNI3_PSEUV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.77	551	308	24	10	512	2	499	8e-17	94.7
rs:WP_044720923	hypothetical protein [Streptococcus suis].	34.43	183	107	7	5	180	3	179	8e-17	89.7
rs:WP_046381022	DNA topoisomerase I [Bacillus sp. LM 4-2].	25.09	530	320	19	112	607	82	568	8e-17	94.7
rs:WP_047252202	DNA topoisomerase I [Corynebacterium testudinoris].	26.38	470	278	19	86	505	77	528	8e-17	95.1
tr:E3ZYQ7_LISSE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.49	419	262	14	112	504	82	480	8e-17	94.7
rs:WP_044444178	DNA topoisomerase I, partial [Bacillus mycoides].	27.76	299	202	7	252	539	18	313	8e-17	94.4
rs:WP_004826339	DNA topoisomerase I [Peptoniphilus lacrimalis].	25.29	522	318	19	7	504	6	479	8e-17	94.7
rs:WP_003846154	DNA topoisomerase I [Corynebacterium ammoniagenes].	24.73	554	327	24	2	505	5	518	8e-17	95.1
rs:WP_008807785	MULTISPECIES: topoisomerase I [Klebsiella].	24.20	533	330	18	7	505	6	498	8e-17	94.7
rs:WP_022297042	DNA topoisomerase [Clostridium sp. CAG:465].	24.72	534	305	20	7	504	19	491	8e-17	94.4
rs:WP_038004586	MULTISPECIES: DNA topoisomerase I [Thalassobacter].	25.23	535	314	21	4	505	1	482	8e-17	94.7
rs:WP_021680539	DNA topoisomerase I [Ruminococcus callidus].	24.24	524	327	16	7	505	5	483	8e-17	94.4
rs:WP_046332083	DNA topoisomerase I [Lactobacillus kimbladii].	23.52	523	325	17	7	505	15	486	8e-17	94.7
rs:WP_016171692	DNA topoisomerase 1 [Enterococcus dispar].	23.64	533	314	18	7	504	7	481	8e-17	94.4
rs:WP_023094336	DNA topoisomerase I [Pseudomonas aeruginosa].	24.95	497	296	19	86	553	58	506	8e-17	94.4
rs:WP_025146647	DNA topoisomerase I [Sphingobacterium sp. H1ai].	24.06	532	300	19	7	504	6	467	8e-17	94.7
rs:WP_022937729	DNA topoisomerase I [Dielma fastidiosa].	26.08	556	308	24	7	522	5	497	8e-17	94.7
rs:WP_021317628	DNA topoisomerase I [Sphingobium ummariense].	25.48	526	310	21	7	505	4	474	8e-17	94.7
rs:WP_019152799	DNA topoisomerase I [Bacillus massiliosenegalensis].	23.91	527	323	19	7	505	6	482	8e-17	94.4
rs:WP_045096318	DNA topoisomerase I [Legionella fallonii].	24.67	535	321	15	7	505	6	494	8e-17	94.7
rs:WP_011025719	DNA topoisomerase I [Caldanaerobacter subterraneus].	24.82	568	339	20	7	553	6	506	8e-17	94.4
rs:WP_031882457	DNA topoisomerase 1 [Staphylococcus aureus].	25.57	528	310	22	7	505	6	479	8e-17	94.4
rs:WP_044360969	DNA topoisomerase I [Staphylococcus microti].	25.10	526	313	20	7	504	6	478	8e-17	94.4
rs:WP_025684918	DNA topoisomerase I [Paenibacillus sp. 1-49].	24.52	526	319	19	7	504	6	481	8e-17	94.4
rs:WP_024237790	DNA topoisomerase I [Escherichia coli].	24.54	542	317	21	7	505	6	498	8e-17	94.7
rs:WP_035358326	DNA topoisomerase I [Acholeplasma equifetale].	24.90	498	310	19	26	504	12	464	8e-17	94.4
rs:WP_015010243	DNA topoisomerase I [Amphibacillus xylanus].	24.33	526	322	18	7	505	6	482	8e-17	94.4
rs:WP_043273977	DNA topoisomerase I [Pseudomonas sp. AAC].	21.99	532	343	18	88	593	66	551	8e-17	94.4
rs:WP_043831062	DNA topoisomerase I [Roseomonas aerilata].	25.42	539	314	24	7	505	5	495	8e-17	94.7
rs:WP_045335024	DNA topoisomerase I [Enterobacter cloacae].	25.23	535	322	20	7	505	6	498	8e-17	94.7
tr:A0A090LVT9_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.76	528	309	22	7	505	8	481	8e-17	94.4
rs:WP_044862322	DNA topoisomerase I, partial [Escherichia coli].	24.77	537	322	21	7	505	6	498	8e-17	94.4
rs:WP_031755155	DNA topoisomerase I [Pseudomonas aeruginosa].	25.25	495	297	18	86	553	58	506	8e-17	94.4
rs:WP_016622928	hypothetical protein, partial [Enterococcus faecalis].	33.73	166	100	4	375	531	16	180	8e-17	89.7
rs:WP_008856759	DNA topoisomerase I [Lactobacillus kisonensis].	24.38	525	320	20	5	504	24	496	8e-17	94.4
rs:WP_041726937	DNA topoisomerase I, partial [Desulfurispirillum indicum].	24.59	545	328	22	1	512	1	495	8e-17	94.4
rs:WP_031368241	hypothetical protein, partial [Clostridium botulinum].	26.01	273	180	9	199	460	11	272	8e-17	91.3
rs:WP_003833325	MULTISPECIES: topoisomerase I [Citrobacter].	24.49	535	326	19	7	505	6	498	8e-17	94.7
rs:WP_033982829	DNA topoisomerase I [Pseudomonas aeruginosa].	25.25	499	294	19	86	553	58	508	8e-17	94.4
tr:C3XFJ0_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.09	437	271	15	109	512	130	547	8e-17	94.7
rs:WP_015711082	DNA topoisomerase I [Treponema azotonutricium].	26.42	530	305	25	5	504	18	492	8e-17	94.4
rs:WP_046097185	DNA topoisomerase I, partial [Mycoplasma meleagridis].	24.66	442	283	13	89	504	61	478	8e-17	94.4
rs:WP_022050564	DNA topoisomerase [Ruminococcus sp. CAG:254].	24.29	638	375	27	7	605	5	573	8e-17	94.4
rs:WP_023124573	DNA topoisomerase I [Pseudomonas aeruginosa].	25.15	497	295	19	86	553	58	506	9e-17	94.4
rs:WP_038315269	DNA topoisomerase I [Kingella kingae].	26.83	451	266	15	103	510	73	502	9e-17	94.7
rs:WP_004347969	DNA topoisomerase I [Pseudomonas aeruginosa].	25.25	499	294	19	86	553	58	508	9e-17	94.4
rs:WP_024775835	DNA topoisomerase I [Arcobacter cibarius].	25.56	536	308	22	7	505	5	486	9e-17	94.7
rs:WP_026739446	DNA topoisomerase I [Lonsdalea quercina].	25.19	540	316	22	7	505	6	498	9e-17	94.7
rs:WP_028832336	DNA topoisomerase I, partial [Proteobacteria bacterium JGI 0000113-E04].	26.88	439	264	17	89	504	2	406	9e-17	94.4
rs:WP_002169243	DNA topoisomerase III [Bacillus cereus].	29.90	204	125	6	5	206	4	191	9e-17	89.7
rs:WP_006870710	DNA topoisomerase I [Legionella drancourtii].	25.37	536	317	16	7	505	6	495	9e-17	94.4
rs:WP_022296446	MULTISPECIES: DNA topoisomerase [Escherichia].	24.54	542	317	21	7	505	6	498	9e-17	94.7
tr:A0A098EFI4_ANAPH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.38	532	320	21	4	504	1	486	9e-17	94.7
rs:WP_008303258	topoisomerase I [Acinetobacter sp. HA].	23.84	537	327	18	7	505	26	518	9e-17	94.7
rs:WP_003081026	DNA topoisomerase I [Streptococcus macacae].	24.86	519	320	17	7	505	24	492	9e-17	94.4
rs:WP_047119826	DNA topoisomerase I [Arthrobacter sp. YC-RL1].	25.18	560	310	27	7	505	14	525	9e-17	94.7
rs:WP_012455374	DNA topoisomerase I [Methylobacterium populi].	24.86	551	321	23	4	510	1	502	9e-17	94.7
rs:WP_033924726	DNA topoisomerase I [Sphingomonas sp. 35-24ZXX].	26.29	525	307	22	7	505	4	474	9e-17	94.7
rs:WP_034035504	DNA topoisomerase I [Pseudomonas aeruginosa].	25.25	499	294	19	86	553	58	508	9e-17	94.4
rs:WP_010494155	DNA topoisomerase I [Lactobacillus acidipiscis].	25.67	526	310	20	7	505	1	472	9e-17	94.4
rs:WP_001607265	DNA topoisomerase 1 [Escherichia coli].	24.49	535	326	20	7	505	6	498	9e-17	94.7
rs:WP_004294133	DNA topoisomerase III [Bacteroides eggerthii].	21.29	559	365	17	4	536	1	510	9e-17	94.0
rs:WP_005524983	DNA topoisomerase I [Corynebacterium matruchotii].	24.53	530	307	21	40	505	29	529	9e-17	94.7
rs:WP_010858431	DNA topoisomerase I [Lysinibacillus sphaericus].	25.57	442	276	15	93	504	63	481	9e-17	94.4
rs:WP_034491437	DNA topoisomerase I [Afifella pfennigii].	26.34	558	298	29	7	510	4	502	9e-17	94.7
rs:WP_042738862	DNA topoisomerase I [Staphylococcus gallinarum].	24.95	529	311	18	7	505	6	478	9e-17	94.4
rs:WP_022065862	DNA topoisomerase [Klebsiella variicola CAG:634].	24.20	533	330	18	7	505	6	498	9e-17	94.7
rs:WP_011450708	DNA topoisomerase I [Anaplasma phagocytophilum].	25.38	532	320	21	4	504	1	486	9e-17	94.7
rs:WP_006838846	DNA topoisomerase I, partial [Bacillus sp. SG-1].	25.29	526	314	19	7	504	6	480	9e-17	93.6
rs:WP_031631577	DNA topoisomerase I [Pseudomonas aeruginosa].	25.15	497	295	19	86	553	58	506	9e-17	94.4
rs:WP_011759437	topoisomerase I [Shewanella amazonensis].	23.25	542	333	18	7	505	6	507	9e-17	94.7
rs:WP_002348936	DNA topoisomerase, partial [Enterococcus faecium].	32.34	201	122	4	376	563	32	231	9e-17	92.4
rs:WP_038098345	hypothetical protein, partial [Thioalkalivibrio sp. HK1].	26.96	460	265	17	97	505	67	506	9e-17	94.7
rs:WP_003560399	DNA topoisomerase I [Lactobacillus buchneri].	25.26	483	309	18	47	504	44	499	9e-17	94.4
rs:WP_046159897	DNA topoisomerase I [Caldanaerobacter subterraneus].	24.82	568	339	20	7	553	6	506	9e-17	94.4
rs:WP_031911407	DNA topoisomerase I [Staphylococcus aureus].	25.62	527	311	21	7	505	6	479	9e-17	94.4
rs:WP_009207200	DNA topoisomerase I [Sulfuricella denitrificans].	26.14	547	308	22	1	505	1	493	9e-17	94.4
rs:WP_026398617	DNA topoisomerase I [Acetobacter nitrogenifigens].	24.82	552	315	26	7	510	5	504	9e-17	94.7
rs:WP_034897251	DNA topoisomerase I [Erwinia typographi].	23.94	543	319	20	7	505	6	498	9e-17	94.7
rs:WP_028487358	DNA topoisomerase I [Thiomicrospira chilensis].	24.48	531	297	21	7	504	5	464	9e-17	94.4
rs:WP_011702101	DNA topoisomerase I [Listeria welshimeri].	26.49	419	262	14	112	504	82	480	9e-17	94.4
rs:WP_000774776	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	9e-17	94.4
rs:WP_035081584	DNA topoisomerase I [Caulobacter henricii].	25.05	547	320	24	4	510	1	497	9e-17	94.7
rs:WP_000513608	DNA topoisomerase I subunit omega, partial [Shigella dysenteriae].	24.58	537	323	20	7	505	6	498	9e-17	94.4
rs:WP_046599101	DNA topoisomerase I [Pseudomonas aeruginosa].	25.31	478	287	18	99	553	76	506	9e-17	94.0
rs:WP_001385318	DNA topoisomerase 1 [Escherichia coli].	24.54	542	317	21	7	505	6	498	9e-17	94.7
tr:F4SWU8_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.54	542	317	21	7	505	28	520	9e-17	94.7
gp:CP003885_439	DNA topoisomerase I [Legionella pneumophila subsp. pneumophila LPE509]	26.56	482	282	15	72	505	11	468	1e-16	94.4
rs:WP_029916231	DNA topoisomerase I [Caulobacter sp. UNC358MFTsu5.1].	25.23	547	319	24	4	510	1	497	1e-16	94.7
tr:X0TLT1_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_S01025 {ECO:0000313|EMBL:GAF94503.1}; Flags: Fragment;	31.23	301	174	13	140	430	4	281	1e-16	91.3
rs:WP_012874441	DNA topoisomerase I [Thermobaculum terrenum].	25.23	551	301	23	7	504	6	498	1e-16	94.4
rs:WP_001526939	DNA topoisomerase 1 [Escherichia coli].	24.54	542	317	21	7	505	6	498	1e-16	94.4
rs:WP_021151812	DNA topoisomerase I [Streptococcus sp. HSISS3].	24.71	526	309	20	7	504	34	500	1e-16	94.4
rs:WP_019002142	hypothetical protein [Succinimonas amylolytica].	24.19	525	324	17	7	505	6	482	1e-16	94.4
rs:WP_016171183	hypothetical protein, partial [Enterococcus faecium].	32.34	201	122	4	376	563	13	212	1e-16	92.0
rs:WP_027022206	DNA topoisomerase I [Conchiformibius steedae].	26.73	505	288	21	43	505	27	491	1e-16	94.4
rs:WP_042085044	DNA topoisomerase I [Acinetobacter bereziniae].	26.06	472	277	18	56	505	97	518	1e-16	94.4
rs:WP_016532151	DNA topoisomerase I subunit omega, partial [Klebsiella pneumoniae].	24.95	537	321	22	7	505	6	498	1e-16	93.6
rs:WP_012698584	DNA topoisomerase I [Laribacter hongkongensis].	25.38	599	318	25	7	557	6	523	1e-16	94.4
rs:WP_039627787	DNA topoisomerase I [Campylobacter lari].	25.18	409	271	11	107	500	78	466	1e-16	94.4
rs:WP_005035632	MULTISPECIES: topoisomerase I [Acinetobacter].	26.06	472	277	18	56	505	97	518	1e-16	94.4
rs:WP_033444675	DNA topoisomerase I, partial [Candidatus Odyssella thessalonicensis].	26.15	543	306	25	5	505	3	492	1e-16	94.4
rs:WP_044175108	DNA topoisomerase I [Enterobacter massiliensis].	24.39	533	329	18	7	505	6	498	1e-16	94.4
rs:WP_014614088	DNA topoisomerase I [Staphylococcus pseudintermedius].	25.19	528	310	21	7	504	6	478	1e-16	94.4
rs:WP_044433901	DNA topoisomerase I [Acinetobacter ursingii].	24.20	533	330	19	7	505	27	519	1e-16	94.4
rs:WP_020054580	hypothetical protein [alpha proteobacterium SCGC AAA015-N04].	26.18	531	308	21	7	505	4	482	1e-16	94.4
rs:WP_035253559	DNA topoisomerase I [Agrococcus lahaulensis].	23.91	548	331	20	7	505	6	516	1e-16	94.4
rs:WP_044644877	DNA topoisomerase I [Paenibacillus terrae].	24.52	526	319	19	7	504	6	481	1e-16	94.4
rs:WP_045970886	DNA topoisomerase I [Xenorhabdus doucetiae].	25.43	460	291	17	69	505	68	498	1e-16	94.4
rs:WP_041692327	DNA topoisomerase I, partial [Erwinia billingiae].	23.98	538	325	19	7	505	6	498	1e-16	94.4
rs:WP_017030849	topoisomerase I [Vibrio breoganii].	23.43	542	328	20	7	505	6	503	1e-16	94.4
rs:WP_002661675	DNA topoisomerase I [Bergeyella zoohelcum].	23.80	521	310	20	7	504	6	462	1e-16	94.4
rs:WP_008245900	DNA topoisomerase I [Sulfurovum sp. AR].	25.92	436	269	14	97	505	69	477	1e-16	94.4
rs:WP_014998125	topoisomerase I [Alteromonas macleodii].	25.99	431	278	14	93	505	99	506	1e-16	94.4
rs:WP_031913953	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	1e-16	94.0
tr:A0A077VAY5_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.24	527	311	21	7	504	8	480	1e-16	94.0
rs:WP_036688567	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	25.00	528	314	20	7	504	6	481	1e-16	94.0
rs:WP_004813291	DNA topoisomerase I [Acinetobacter schindleri].	23.84	537	327	18	7	505	26	518	1e-16	94.4
tr:E4QCU7_CALH1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.64	571	341	21	7	553	5	504	1e-16	94.0
rs:WP_004781880	DNA topoisomerase I [Acinetobacter sp. NIPH 899].	23.65	537	328	17	7	505	26	518	1e-16	94.4
tr:D5T991_LEGP2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.56	482	282	15	72	505	11	468	1e-16	94.0
rs:WP_010782788	hypothetical protein, partial [Enterococcus faecium].	32.34	201	122	4	376	563	7	206	1e-16	92.0
rs:WP_047353322	DNA topoisomerase I [Enterobacter sp. GN02315].	25.33	533	324	20	7	505	6	498	1e-16	94.4
rs:WP_000774777	DNA topoisomerase 1 [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	1e-16	94.0
rs:WP_015881378	DNA topoisomerase I [Exiguobacterium sp. AT1b].	23.81	630	372	23	7	599	6	564	1e-16	94.0
rs:WP_039025800	DNA topoisomerase I [Escherichia coli].	24.39	533	329	19	7	505	6	498	1e-16	94.4
rs:WP_046660009	DNA topoisomerase I, partial [Escherichia coli].	24.77	537	322	21	7	505	6	498	1e-16	94.0
rs:WP_046647868	DNA topoisomerase I [Corynebacterium minutissimum].	24.77	541	329	21	5	505	10	512	1e-16	94.4
rs:WP_034123499	DNA topoisomerase I, partial [Peptococcaceae bacterium BICA1-7].	23.70	616	361	23	5	586	7	547	1e-16	94.0
rs:WP_011421751	DNA topoisomerase I [Anaeromyxobacter dehalogenans].	24.20	562	312	23	2	505	45	550	1e-16	94.4
tr:A0A077V3Z6_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.24	527	311	21	7	504	8	480	1e-16	94.0
rs:WP_008344821	MULTISPECIES: DNA topoisomerase I [Bacillus].	26.60	421	259	14	112	504	82	480	1e-16	94.0
rs:WP_037987568	DNA topoisomerase I [Thalassospira permensis].	25.56	540	313	23	4	505	1	489	1e-16	94.4
rs:WP_006986741	DNA topoisomerase I [Cardiobacterium valvarum].	24.53	530	319	18	7	505	6	485	1e-16	94.4
rs:WP_018768948	DNA topoisomerase I [Arthrobacter sp. 162MFSha1.1].	25.18	548	320	19	7	505	12	518	1e-16	94.4
rs:WP_006810845	MULTISPECIES: topoisomerase I [Enterobacter].	25.33	533	324	20	7	505	6	498	1e-16	94.4
rs:WP_024262109	DNA topoisomerase I [Escherichia coli].	24.54	542	317	21	7	505	6	498	1e-16	94.4
rs:WP_005656946	DNA topoisomerase III [Bacteroides stercoris].	22.06	612	401	23	4	590	1	561	1e-16	93.6
tr:D0YYM1_LISDA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.60	461	288	17	69	505	45	474	1e-16	94.4
rs:WP_005032880	topoisomerase I [Shigella dysenteriae].	24.17	542	319	20	7	505	6	498	1e-16	94.4
rs:WP_042108431	DNA topoisomerase I, partial [Escherichia coli].	24.77	537	322	21	7	505	6	498	1e-16	94.0
rs:WP_018076642	DNA topoisomerase I [Thiobacillus denitrificans].	26.06	426	268	15	107	505	75	480	1e-16	94.4
rs:WP_042853351	DNA topoisomerase III, partial [Staphylococcus aureus].	31.43	210	131	7	5	208	3	205	1e-16	89.7
tr:D8MSU2_ERWBE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.98	538	325	19	7	505	6	498	1e-16	94.4
rs:WP_031786944	DNA topoisomerase I [Staphylococcus aureus].	25.24	527	311	21	7	504	6	478	1e-16	94.0
rs:WP_008473278	DNA topoisomerase [Lactobacillus gigeriorum].	23.91	435	291	17	7	424	5	416	1e-16	94.0
rs:WP_035038494	DNA topoisomerase I [Devosia sp. DBB001].	26.68	461	281	17	80	505	46	484	1e-16	94.4
rs:WP_044335050	DNA topoisomerase I [Sphingomonas sp. WHSC-8].	24.90	522	318	20	7	505	4	474	1e-16	94.4
rs:WP_018922566	DNA topoisomerase I [Salsuginibacillus kocurii].	24.20	624	371	24	7	598	6	559	1e-16	94.0
rs:WP_017367241	MULTISPECIES: DNA topoisomerase I [Bacillus].	26.60	421	259	14	112	504	82	480	1e-16	94.0
rs:WP_009157827	DNA topoisomerase I [Thalassobium sp. R2A62].	24.86	551	312	22	4	510	1	493	1e-16	94.4
tr:N1W6Q6_9LEPT	SubName: Full=Putative DNA topoisomerase I {ECO:0000313|EMBL:EMY68927.1};	23.60	534	332	19	81	584	2	489	1e-16	93.6
rs:WP_044806905	DNA topoisomerase I, partial [Escherichia coli].	24.77	537	322	21	7	505	6	498	1e-16	94.0
rs:WP_035088805	DNA topoisomerase I [Devosia sp. 17-2-E-8].	26.68	461	281	17	80	505	46	484	1e-16	94.4
rs:WP_028830031	DNA topoisomerase I [Proteocatella sphenisci].	24.21	570	348	21	7	555	6	512	1e-16	94.0
rs:WP_012968444	topoisomerase I [Klebsiella variicola].	23.93	535	329	19	7	505	6	498	1e-16	94.4
rs:WP_036752627	DNA topoisomerase I [Peptoniphilus lacrimalis].	25.29	522	318	19	7	504	6	479	1e-16	94.0
tr:K1S3C4_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC55112.1}; Flags: Fragment;	29.24	277	152	10	162	430	6	246	1e-16	90.9
rs:WP_033659603	DNA topoisomerase, partial [Enterococcus faecium].	32.74	226	135	8	5	223	33	248	1e-16	90.5
rs:WP_044069817	DNA topoisomerase I [Pseudomonas aeruginosa].	25.10	478	288	18	99	553	76	506	1e-16	94.0
rs:WP_037537327	DNA topoisomerase I [Staphylococcus haemolyticus].	24.43	528	314	18	7	504	6	478	1e-16	94.0
rs:WP_007089913	DNA topoisomerase I [Thalassospira xiamenensis].	25.56	540	313	23	4	505	1	489	1e-16	94.4
gp:FJ666348_34	TraB [Synthetic plasmid pMOL98]	24.47	523	325	17	43	543	25	499	1e-16	94.0
rs:WP_026635325	DNA topoisomerase I [Dyella japonica].	25.92	544	309	21	7	505	6	500	1e-16	94.4
rs:WP_033978938	DNA topoisomerase I [Pseudomonas aeruginosa].	24.95	497	296	19	86	553	58	506	1e-16	94.0
rs:WP_035700740	DNA topoisomerase I [Bacillus altitudinis].	26.60	421	259	14	112	504	82	480	1e-16	94.0
rs:WP_036764082	DNA topoisomerase I [Photobacterium damselae].	25.60	461	288	17	69	505	75	504	1e-16	94.4
tr:Q48NI0_PSE14	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AAZ34932.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AAZ34932.1};	39.02	123	67	3	8	130	5	119	1e-16	93.2
rs:WP_040466951	DNA topoisomerase I [Eubacterium brachy].	24.47	523	315	18	8	505	1	468	1e-16	94.0
rs:WP_040234733	DNA topoisomerase I, partial [Klebsiella pneumoniae].	24.86	535	324	20	7	505	6	498	1e-16	93.6
rs:WP_002201903	DNA topoisomerase III [Bacillus cereus].	29.90	204	125	6	5	206	4	191	1e-16	89.4
rs:WP_039883879	DNA topoisomerase III, partial [Achromobacter piechaudii].	33.54	158	90	4	406	552	1	154	1e-16	89.7
rs:WP_004890309	DNA topoisomerase I [Acinetobacter schindleri].	23.65	537	328	18	7	505	26	518	1e-16	94.4
rs:WP_038640964	DNA topoisomerase I [Citrobacter freundii].	24.30	535	327	19	7	505	6	498	1e-16	94.4
tr:A0A0A8HYI3_CAMLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.18	409	271	11	107	500	77	465	1e-16	94.0
rs:WP_024424184	MULTISPECIES: DNA topoisomerase I [Bacillus].	25.24	531	318	20	112	607	82	568	1e-16	94.0
rs:WP_014105207	DNA topoisomerase I [Komagataeibacter medellinensis].	25.23	555	310	26	7	510	5	505	1e-16	94.4
rs:WP_037468625	DNA topoisomerase I [Sphingobium herbicidovorans].	25.05	523	316	20	7	505	4	474	1e-16	94.0
rs:WP_014417765	MULTISPECIES: DNA topoisomerase I [Bacillales].	26.18	424	257	14	112	504	82	480	1e-16	94.0
rs:WP_036202949	DNA topoisomerase I [Lysinibacillus sinduriensis].	28.24	425	248	16	112	504	82	481	1e-16	94.0
rs:WP_020805409	DNA topoisomerase, partial [Klebsiella pneumoniae].	33.72	172	110	3	285	453	29	199	1e-16	89.7
rs:WP_007025070	DNA topoisomerase I [Saccharomonospora paurometabolica].	25.47	479	285	16	86	510	89	549	1e-16	94.4
rs:WP_033757842	DNA topoisomerase I [Pantoea agglomerans].	25.60	457	294	16	69	505	77	507	1e-16	94.0
rs:WP_028405688	DNA topoisomerase I [Bacillus sp. J13].	24.62	528	316	20	7	504	6	481	1e-16	94.0
rs:WP_009490010	DNA topoisomerase I [Catellicoccus marimammalium].	24.23	520	324	18	7	504	7	478	1e-16	94.0
rs:WP_008336478	DNA topoisomerase I [Alicyclobacillus acidocaldarius].	25.24	527	314	20	7	504	6	481	1e-16	94.0
tr:V8C8D1_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.50	449	270	17	90	505	106	527	1e-16	94.0
rs:WP_043943121	DNA topoisomerase I, partial [Salmonella enterica].	25.80	500	284	19	7	474	6	450	1e-16	92.8
rs:WP_046833028	hypothetical protein [Xanthomonas axonopodis].	24.41	426	268	14	107	504	75	474	1e-16	94.0
rs:WP_034530828	DNA topoisomerase I [Lactobacillus kunkeei].	26.48	423	265	14	107	505	92	492	1e-16	94.0
rs:WP_025785060	MULTISPECIES: DNA topoisomerase I [Sporosarcina].	24.95	525	318	19	7	504	6	481	1e-16	94.0
rs:WP_031591590	DNA topoisomerase I [Pantoea agglomerans].	25.60	457	294	16	69	505	77	507	1e-16	94.0
rs:WP_013361711	DNA topoisomerase I [[Clostridium] sticklandii].	24.90	526	312	21	7	504	6	476	1e-16	94.0
rs:WP_028387468	DNA topoisomerase I [Legionella geestiana].	26.35	463	287	13	80	505	48	493	1e-16	94.0
rs:WP_020223114	DNA topoisomerase I [Holdemania massiliensis].	27.05	440	266	20	107	517	79	492	1e-16	94.0
rs:WP_032261103	DNA topoisomerase 1 [Escherichia coli].	24.49	535	326	20	7	505	6	498	1e-16	94.0
tr:M5RDN2_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.60	421	259	14	112	504	84	482	1e-16	94.0
rs:WP_004101613	DNA topoisomerase I [Thermosipho africanus].	24.60	622	360	22	7	604	2	538	1e-16	94.0
rs:WP_017020611	topoisomerase I [Aliivibrio logei].	25.43	460	290	19	69	505	74	503	1e-16	94.0
rs:WP_034561232	DNA topoisomerase I [Helicobacter macacae].	26.50	449	270	17	90	505	56	477	1e-16	94.0
tr:A0A0A8VSW0_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.31	573	328	21	7	553	6	504	1e-16	94.0
rs:WP_029413081	DNA topoisomerase I [Acidobacteria bacterium JGI 0001001-H03].	24.82	568	334	21	7	555	6	499	1e-16	94.0
rs:WP_014544362	topoisomerase I [Erwinia sp. Ejp617].	26.20	458	290	16	69	505	68	498	1e-16	94.0
rs:WP_027088939	DNA topoisomerase I [[Clostridium] saccharogumia].	24.81	528	332	19	80	584	51	536	1e-16	94.0
tr:A0A0C7SWK7_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.61	573	332	20	7	553	6	504	1e-16	94.0
tr:C0EHG4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.82	440	267	17	97	505	80	495	1e-16	94.0
rs:WP_010244475	MULTISPECIES: topoisomerase I [Pantoea].	25.60	457	294	16	69	505	77	507	1e-16	94.0
tr:S7J7E5_CHLPS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.49	539	317	21	10	505	2	493	1e-16	94.0
tr:N2BCF8_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.30	441	265	15	109	512	130	547	1e-16	94.0
rs:WP_033787708	DNA topoisomerase I [Pantoea agglomerans].	25.60	457	294	16	69	505	77	507	1e-16	94.0
rs:WP_027971276	DNA topoisomerase I [Streptococcus plurextorum].	23.64	626	366	23	7	603	24	566	1e-16	94.0
rs:WP_024817958	DNA topoisomerase I [Arthrobacter sp. 31Y].	25.36	548	319	19	7	505	12	518	1e-16	94.0
rs:WP_039223928	DNA topoisomerase I [Alteromonas marina].	25.99	431	278	14	93	505	99	506	1e-16	94.0
rs:WP_041723101	DNA topoisomerase I [Caldicellulosiruptor hydrothermalis].	23.64	571	341	21	7	553	6	505	1e-16	93.6
rs:WP_004415122	DNA topoisomerase I [Mycoplasma arginini].	25.14	525	301	21	7	504	6	465	1e-16	93.6
rs:WP_040686122	DNA topoisomerase I [Nocardia vinacea].	25.34	592	339	23	7	550	19	555	1e-16	94.0
rs:WP_027066041	DNA topoisomerase I [Maribacter sp. Hel_I_7].	25.29	518	309	17	7	504	6	465	1e-16	94.0
rs:WP_043088831	DNA topoisomerase I [Pseudomonas aeruginosa].	24.36	505	289	19	86	553	58	506	1e-16	93.6
rs:WP_013643118	DNA topoisomerase I [Streptococcus gallolyticus].	24.71	526	310	19	7	504	32	499	1e-16	94.0
rs:WP_027338521	DNA topoisomerase I [Helicobacter bilis].	26.14	440	273	15	109	515	75	495	1e-16	94.0
rs:WP_039738802	DNA topoisomerase I, partial [Saccharomonospora halophila].	25.52	482	281	17	86	510	99	559	1e-16	94.0
rs:WP_011840645	DNA topoisomerase I [Rhodobacter sphaeroides].	25.32	545	317	24	4	510	1	493	1e-16	94.0
rs:WP_045715043	DNA topoisomerase I, partial [Salmonella enterica].	27.14	420	258	16	107	505	6	398	1e-16	94.0
rs:XP_009353313	PREDICTED: DNA topoisomerase 3 isoform X2 [Pyrus x bretschneideri].	26.42	530	298	22	36	504	49	547	1e-16	94.0
tr:A0A0C7QKE4_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.61	573	332	20	7	553	6	504	1e-16	93.6
gp:KJ850907_18	TraB [uncultured bacterium]	23.52	523	330	16	43	543	25	499	1e-16	94.0
tr:E0PDM1_STREI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.71	526	310	19	7	504	70	537	1e-16	94.0
rs:WP_039178505	DNA topoisomerase I [Bacillus sp. WP8].	25.24	531	318	20	112	607	82	568	1e-16	93.6
tr:R3UNR0_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.57	259	172	8	295	544	2	256	1e-16	92.4
rs:WP_034036278	DNA topoisomerase I [Pseudomonas aeruginosa].	25.05	495	298	19	86	553	58	506	1e-16	93.6
rs:WP_018712559	hypothetical protein [Campylobacter ureolyticus].	24.08	519	324	17	7	505	5	473	1e-16	93.6
rs:WP_041973403	MULTISPECIES: DNA topoisomerase I [Streptococcus].	24.71	526	310	19	7	504	34	501	1e-16	93.6
rs:WP_042041488	DNA topoisomerase I [Aeromonas rivuli].	22.68	538	335	18	7	505	6	501	1e-16	94.0
rs:WP_038214901	DNA topoisomerase I [Xenorhabdus bovienii].	25.22	460	292	16	69	505	66	496	1e-16	94.0
rs:WP_013100547	DNA topoisomerase I [Methanocaldococcus infernus].	29.09	330	187	12	7	322	4	300	1e-16	94.0
rs:WP_013100547	DNA topoisomerase I [Methanocaldococcus infernus].	28.10	242	147	7	330	567	463	681	6e-09	69.3
rs:WP_026742481	DNA topoisomerase I [Lonsdalea quercina].	25.19	540	316	22	7	505	6	498	1e-16	94.0
rs:WP_036239280	DNA topoisomerase I [Marinospirillum insulare].	24.71	437	286	14	88	505	88	500	1e-16	94.0
tr:I2C540_BACAM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.18	424	257	14	112	504	84	482	1e-16	93.6
rs:WP_028013404	DNA topoisomerase I [Enterobacter cloacae].	24.44	540	320	20	7	505	6	498	1e-16	94.0
tr:C9BIL0_ENTFC	SubName: Full=Topoisomerase {ECO:0000313|EMBL:EEV52135.1};	29.08	196	129	5	42	234	11	199	1e-16	89.4
rs:WP_039076930	DNA topoisomerase I [Enterobacter sp. Bisph2].	23.26	533	335	18	7	505	6	498	1e-16	94.0
rs:WP_009117526	DNA topoisomerase I [Neisseria wadsworthii].	25.96	520	290	21	107	581	77	546	1e-16	94.0
rs:WP_036889220	DNA topoisomerase I, partial [Prevotella aurantiaca].	26.69	341	211	11	5	333	3	316	1e-16	90.9
tr:A0A0A1SK48_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.61	573	332	20	7	553	6	504	1e-16	93.6
tr:A0A0C7P0Z4_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.61	573	332	20	7	553	6	504	1e-16	93.6
tr:R2NT98_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOH42604.1};	31.68	202	124	4	375	563	1	201	1e-16	91.7
rs:WP_023103773	DNA topoisomerase I [Pseudomonas aeruginosa].	24.95	497	296	19	86	553	58	506	1e-16	93.6
tr:A0A0E1XFF3_STRGY	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EFM29549.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFM29549.1};	24.71	526	310	19	7	504	70	537	1e-16	93.6
rs:WP_036301768	DNA topoisomerase I [Microbacterium sp. C448].	23.46	584	355	21	7	550	8	539	1e-16	94.0
rs:WP_039433148	DNA topoisomerase I [Vibrio navarrensis].	23.57	454	306	13	69	505	74	503	1e-16	94.0
rs:WP_000774789	DNA topoisomerase I [Staphylococcus aureus].	25.19	528	312	21	7	505	6	479	2e-16	93.6
rs:WP_036373819	DNA topoisomerase I [Mitsuokella jalaludinii].	24.23	615	353	28	7	580	36	578	2e-16	93.6
rs:WP_023155299	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	2e-16	94.0
rs:WP_018029792	DNA topoisomerase I [Streptococcus ferus].	24.20	529	309	19	7	504	24	491	2e-16	93.6
rs:WP_024556117	DNA topoisomerase I [Cronobacter pulveris].	24.02	533	332	18	7	505	6	499	2e-16	94.0
rs:WP_039693667	DNA topoisomerase I [Streptococcus gallolyticus].	24.71	526	310	19	7	504	32	499	2e-16	93.6
rs:WP_015849264	endonuclease [Thermococcus sibiricus].	27.67	347	211	13	5	333	3	327	2e-16	94.4
rs:WP_015849264	endonuclease [Thermococcus sibiricus].	26.82	220	126	8	330	539	828	1022	9e-06	59.3
rs:WP_024090959	DNA topoisomerase I [Leisingera methylohalidivorans].	24.96	569	309	25	4	510	1	513	2e-16	94.0
rs:WP_012549908	topoisomerase I [Aliivibrio salmonicida].	25.43	460	290	19	69	505	74	503	2e-16	94.0
tr:A0A077UHQ3_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	528	313	21	7	505	8	481	2e-16	93.6
tr:E5B5W3_ERWAM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.42	439	275	15	88	505	87	498	2e-16	94.0
rs:WP_047370484	DNA topoisomerase I [Kluyvera intermedia].	23.26	533	335	18	7	505	6	498	2e-16	94.0
rs:WP_023425866	DNA topoisomerase I, archaeal [uncultured Acidilobus sp. CIS].	23.90	569	352	21	5	548	14	526	2e-16	93.6
rs:WP_039229698	DNA topoisomerase I [Alteromonas macleodii].	25.99	431	278	14	93	505	99	506	2e-16	94.0
rs:WP_036093842	DNA topoisomerase I [Listeria newyorkensis].	26.49	419	262	14	112	504	82	480	2e-16	93.6
rs:WP_021639560	toprim domain protein, partial [Clostridium sp. KLE 1755].	28.57	231	149	7	7	236	4	219	2e-16	90.1
rs:WP_032025368	DNA topoisomerase I [Acinetobacter baumannii].	23.75	539	324	18	7	505	25	516	2e-16	94.0
rs:WP_031952082	DNA topoisomerase I [Acinetobacter baumannii].	23.75	539	324	18	7	505	25	516	2e-16	94.0
rs:WP_004254195	topoisomerase I [Providencia rettgeri].	26.53	441	272	17	88	505	90	501	2e-16	94.0
rs:WP_027359053	DNA topoisomerase I [Desulforegula conservatrix].	26.43	526	317	19	93	591	63	545	2e-16	93.6
tr:A0A0C7IC58_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.61	573	332	20	7	553	6	504	2e-16	93.6
rs:WP_021127832	DNA topoisomerase I [[Clostridium] sordellii].	24.61	573	332	20	7	553	6	504	2e-16	93.6
rs:WP_029149405	DNA topoisomerase I [Microbacterium indicum].	25.44	452	283	15	95	505	79	517	2e-16	94.0
rs:WP_022869417	DNA topoisomerase I [Yaniella halotolerans].	24.41	549	327	16	7	505	17	527	2e-16	94.0
rs:WP_046204013	DNA topoisomerase I [Corynebacterium argentoratense].	26.05	476	285	18	80	505	68	526	2e-16	94.0
rs:WP_037565328	DNA topoisomerase III, partial [Staphylococcus agnetis].	29.62	260	151	11	1	245	1	243	2e-16	90.1
rs:WP_040438574	DNA topoisomerase I [[Clostridium] methylpentosum].	26.82	440	267	17	97	505	71	486	2e-16	93.6
rs:WP_031892024	DNA topoisomerase III, partial [Staphylococcus aureus].	27.35	234	152	6	7	238	5	222	2e-16	89.7
rs:WP_004828589	DNA topoisomerase I [Anaerococcus lactolyticus].	23.06	633	378	25	7	605	6	563	2e-16	93.6
rs:WP_027825571	DNA topoisomerase I [Lactobacillus psittaci].	25.72	521	314	20	7	504	9	479	2e-16	93.6
tr:M4KRT9_BACIU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.91	530	321	19	112	607	84	570	2e-16	93.6
rs:WP_043065995	DNA topoisomerase I [Aneurinibacillus migulanus].	24.43	528	316	20	7	504	6	480	2e-16	93.6
rs:XP_009353312	PREDICTED: uncharacterized protein LOC103944567 isoform X1 [Pyrus x bretschneideri].	26.37	531	299	22	36	505	376	875	2e-16	94.0
tr:G7ZMZ8_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.24	527	311	21	7	504	8	480	2e-16	93.6
rs:WP_031921358	DNA topoisomerase III, partial [Staphylococcus aureus].	27.35	234	152	6	7	238	5	222	2e-16	90.1
rs:WP_002303238	topoisomerase I [Enterococcus faecium].	29.23	195	128	5	43	234	12	199	2e-16	89.0
rs:WP_004157737	topoisomerase I [Erwinia amylovora].	26.42	439	275	15	88	505	87	498	2e-16	94.0
rs:WP_041741519	DNA topoisomerase I [Caldicellulosiruptor kronotskyensis].	23.29	571	343	21	7	553	6	505	2e-16	93.6
rs:WP_040532974	DNA topoisomerase I [Lactobacillus pobuzihii].	26.01	519	311	21	10	505	2	470	2e-16	93.6
tr:A0A077VUX2_STAAU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.24	527	311	21	7	504	8	480	2e-16	93.6
tr:A0A0C7GJT9_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.61	573	332	20	7	553	6	504	2e-16	93.6
tr:E7G433_9HELI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.16	465	280	16	89	504	64	509	2e-16	93.6
rs:WP_010518278	DNA topoisomerase I [Mesoflavibacter zeaxanthinifaciens].	25.80	562	323	23	7	540	6	501	2e-16	93.6
rs:WP_002498363	DNA topoisomerase I [Staphylococcus epidermidis].	24.81	528	312	18	7	504	6	478	2e-16	93.6
rs:WP_040321351	DNA topoisomerase I [Austwickia chelonae].	24.01	558	334	18	7	510	10	531	2e-16	94.0
rs:WP_043058862	DNA topoisomerase I [Mesorhizobium sp. UASWS1009].	24.23	549	328	17	7	505	17	527	2e-16	94.0
rs:WP_031859570	DNA topoisomerase III, partial [Staphylococcus aureus].	27.35	234	152	6	7	238	5	222	2e-16	89.7
rs:WP_014828436	DNA topoisomerase I [Desulfosporosinus acidiphilus].	26.41	587	323	26	3	555	2	513	2e-16	93.6
rs:WP_035328942	DNA topoisomerase I [Bacillus firmus].	26.67	420	260	15	112	504	82	480	2e-16	93.6
rs:WP_031670651	DNA topoisomerase I [Pseudomonas aeruginosa].	25.42	480	286	18	99	553	76	508	2e-16	93.2
rs:WP_011445453	DNA topoisomerase I [Novosphingobium aromaticivorans].	26.35	539	292	25	7	505	4	477	2e-16	93.6
rs:WP_032104631	DNA topoisomerase I, partial [Klebsiella pneumoniae].	24.39	533	329	19	7	505	6	498	2e-16	93.2
rs:WP_025254952	DNA topoisomerase I [Alteromonas sp. ALT199].	25.99	431	278	14	93	505	99	506	2e-16	94.0
rs:WP_042357400	DNA topoisomerase, partial [Streptococcus equi].	26.86	283	175	9	7	287	4	256	2e-16	90.1
rs:WP_007399927	DNA topoisomerase I [Gluconacetobacter sp. SXCC-1].	25.36	560	303	27	7	510	5	505	2e-16	94.0
rs:WP_024921477	MULTISPECIES: DNA topoisomerase I [Afipia].	25.41	543	307	24	7	505	4	492	2e-16	94.0
rs:WP_031794621	DNA topoisomerase III, partial [Staphylococcus aureus].	27.35	234	152	6	7	238	5	222	2e-16	89.7
rs:WP_034064766	DNA topoisomerase I [Pseudomonas aeruginosa].	24.75	497	297	19	86	553	58	506	2e-16	93.2
rs:WP_010334238	DNA topoisomerase I [Bacillus mojavensis].	26.95	423	255	16	112	504	82	480	2e-16	93.6
rs:WP_015570386	DNA topoisomerase I [Enterobacter cloacae].	25.05	535	323	20	7	505	6	498	2e-16	93.6
tr:A0A0C6FHI5_PSEAI	SubName: Full=Pseudomonas aeruginosa DNA, complete genome, strain: NCGM257 {ECO:0000313|EMBL:BAQ42215.1}; EC=5.99.1.2 {ECO:0000313|EMBL:BAQ42215.1};	24.36	505	289	19	86	553	10	458	2e-16	93.2
rs:WP_034928589	DNA topoisomerase I [Komagataeibacter rhaeticus].	25.36	560	303	27	7	510	5	505	2e-16	94.0
rs:WP_003139282	DNA topoisomerase I [Lactococcus raffinolactis].	25.62	523	309	23	7	504	38	505	2e-16	93.6
rs:WP_031806809	DNA topoisomerase III, partial [Staphylococcus aureus].	27.35	234	152	6	7	238	5	222	2e-16	89.7
rs:WP_022187731	DNA topoisomerase [Azospirillum sp. CAG:260].	26.37	546	304	25	7	510	4	493	2e-16	93.6
rs:WP_016536693	DNA topoisomerase I [Cedecea davisae].	24.78	464	299	15	64	505	63	498	2e-16	93.6
rs:WP_024720597	DNA topoisomerase I [Clostridiales bacterium VE202-01].	24.81	528	332	19	80	584	51	536	2e-16	93.6
rs:WP_041517853	DNA topoisomerase I [Bacillus subtilis].	24.91	530	321	19	112	607	82	568	2e-16	93.6
rs:WP_040038412	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	2e-16	93.6
rs:WP_002443101	topoisomerase I [Shimwellia blattae].	24.73	461	293	17	69	505	71	501	2e-16	93.6
rs:WP_027108419	DNA topoisomerase I [Lacticigenium naphtae].	24.47	523	322	18	7	504	7	481	2e-16	93.6
rs:WP_012447839	DNA topoisomerase I [Natranaerobius thermophilus].	24.31	576	334	24	7	555	6	506	2e-16	93.6
rs:WP_036891772	DNA topoisomerase I, partial [Prevotella corporis].	25.88	340	211	9	7	333	5	316	2e-16	90.5
tr:S5SY71_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.41	272	171	9	306	563	4	268	2e-16	92.0
rs:WP_040773167	DNA topoisomerase I [Nocardia pneumoniae].	24.79	593	343	22	7	550	19	557	2e-16	94.0
rs:WP_015874127	topoisomerase I [Candidatus Hamiltonella defensa].	23.95	547	316	20	7	505	6	500	2e-16	93.6
tr:K1US83_9ZZZZ	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:EKC81125.1};	26.38	235	152	7	329	550	1	227	2e-16	91.3
rs:WP_020082763	hypothetical protein [gamma proteobacterium SCGC AAA076-P09].	23.64	550	333	19	7	512	6	512	2e-16	93.6
rs:WP_014979097	topoisomerase I [Alteromonas macleodii].	25.99	431	278	14	93	505	99	506	2e-16	93.6
rs:WP_033629029	DNA topoisomerase, partial [Enterococcus faecium].	31.84	201	123	4	376	563	10	209	2e-16	91.3
rs:WP_026976557	DNA topoisomerase I [Flavobacterium tegetincola].	26.36	535	280	25	7	504	6	463	2e-16	93.6
tr:E9YZQ1_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.35	542	318	20	7	505	20	512	2e-16	93.2
rs:WP_031921871	DNA topoisomerase III, partial [Staphylococcus aureus].	27.35	234	152	6	7	238	5	222	2e-16	89.7
tr:A0A0C7RVM9_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.61	573	332	20	7	553	6	504	2e-16	93.6
rs:WP_043953492	DNA topoisomerase I [Enterobacter sp. YD4].	23.83	533	332	18	7	505	6	498	2e-16	93.6
rs:WP_022179515	DNA topoisomerase [Firmicutes bacterium CAG:582].	25.67	526	308	20	7	506	4	472	2e-16	93.2
rs:WP_033987969	DNA topoisomerase I [Pseudomonas aeruginosa].	25.15	497	295	20	86	553	58	506	2e-16	93.2
rs:WP_037326601	DNA topoisomerase I [Anaerococcus lactolyticus].	23.06	633	378	25	7	605	6	563	2e-16	93.2
rs:WP_017359093	DNA topoisomerase I [Bacillus pumilus].	26.60	421	259	14	112	504	82	480	2e-16	93.2
rs:WP_034005999	DNA topoisomerase I [Pseudomonas aeruginosa].	24.95	497	296	19	86	553	58	506	2e-16	93.2
rs:WP_023940314	DNA topoisomerase I [Porphyromonas cansulci].	24.28	523	312	17	7	504	6	469	2e-16	93.6
rs:XP_001025000	DNA topoisomerase I [Tetrahymena thermophila SB210].	23.06	594	366	23	1	553	238	781	2e-16	94.0
rs:WP_001554983	DNA topoisomerase 1 [Escherichia coli].	24.30	535	327	20	7	505	6	498	2e-16	93.6
tr:G2PUY5_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.47	571	342	21	7	553	5	504	2e-16	93.2
rs:WP_046526653	DNA topoisomerase I [Bacillus sp. L_1B0_12].	26.60	421	259	14	112	504	82	480	2e-16	93.2
rs:WP_027357341	DNA topoisomerase I [Desulfotomaculum thermocisternum].	24.53	530	322	21	3	504	2	481	2e-16	93.6
rs:WP_023015697	DNA topoisomerase I [Staphylococcus simulans].	24.29	527	315	20	7	504	6	477	2e-16	93.2
rs:WP_029473387	DNA topoisomerase I [Clostridiales bacterium VE202-08].	25.90	556	309	24	7	522	5	497	2e-16	93.6
tr:E6W3Q7_DESIS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.59	545	328	22	1	512	1	495	2e-16	93.6
rs:XP_008378234	PREDICTED: uncharacterized protein LOC103441330 [Malus domestica].	26.27	533	297	22	36	505	326	825	2e-16	93.6
rs:WP_004047861	DNA topoisomerase I [Lactobacillus murinus].	25.38	520	317	20	7	504	23	493	2e-16	93.2
tr:A0A0C7RRP1_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.61	573	332	20	7	553	6	504	2e-16	93.2
rs:WP_012850362	DNA topoisomerase I [Edwardsiella tarda].	24.39	533	316	19	91	591	58	535	2e-16	93.2
rs:WP_014949190	topoisomerase I [Alteromonas macleodii].	25.99	431	278	14	93	505	99	506	2e-16	93.6
rs:WP_025796836	DNA topoisomerase I [Hafnia alvei].	24.95	545	311	22	7	505	6	498	2e-16	93.6
rs:WP_017199192	DNA topoisomerase I [Arthrobacter sp. M2012083].	25.41	547	320	19	7	505	12	518	2e-16	93.6
tr:E7MMK8_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.59	568	333	21	7	549	16	507	2e-16	93.2
rs:WP_032656725	DNA topoisomerase I [Enterobacter sp. DC1].	24.20	533	330	18	7	505	6	498	2e-16	93.6
rs:WP_018163831	DNA topoisomerase I [Streptococcus henryi].	24.48	527	310	20	7	504	26	493	2e-16	93.2
rs:WP_042492497	DNA topoisomerase I [Weissella hellenica].	24.76	525	316	19	7	504	37	509	2e-16	93.2
rs:WP_040627511	DNA topoisomerase I [Solobacterium moorei].	23.59	568	333	21	7	549	5	496	2e-16	93.2
rs:WP_036721378	DNA topoisomerase I [Paracoccus sphaerophysae].	24.02	533	318	21	4	505	1	477	2e-16	93.6
rs:WP_037552772	DNA topoisomerase I [Sphingomonas sp. URHD0057].	25.10	526	312	23	7	505	4	474	2e-16	93.6
rs:WP_004826641	DNA topoisomerase I [Acinetobacter bereziniae].	25.85	472	278	18	56	505	97	518	2e-16	93.6
rs:WP_012896210	DNA topoisomerase I [Thermotoga naphthophila].	25.41	551	322	20	7	544	9	483	2e-16	93.2
rs:WP_027259853	DNA topoisomerase I [Leisingera aquimarina].	25.31	569	307	26	4	510	1	513	2e-16	93.6
rs:WP_001427498	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	2e-16	93.6
rs:WP_023957456	DNA topoisomerase I [Paenibacillus sp. JCM 10914].	24.62	528	316	20	7	504	6	481	2e-16	93.2
rs:WP_040430347	DNA topoisomerase I [Corynebacterium nuruki].	24.87	559	323	22	7	505	2	523	2e-16	93.6
rs:WP_027876542	DNA topoisomerase I [Meiothermus cerbereus].	24.10	610	364	24	1	579	1	542	2e-16	93.6
rs:WP_040205353	DNA topoisomerase III, partial [Klebsiella pneumoniae].	26.97	304	199	8	7	301	4	293	2e-16	90.5
rs:WP_035392076	DNA topoisomerase I [Bacillus sp. UNC125MFCrub1.1].	26.37	421	260	14	112	504	82	480	2e-16	93.2
rs:WP_042049273	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	2e-16	93.6
tr:K6W5C8_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.01	558	334	18	7	510	32	553	2e-16	93.6
tr:E4SE67_CALK2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.29	571	343	21	7	553	5	504	2e-16	93.2
rs:WP_045590468	DNA topoisomerase I [Vibrio vulnificus].	25.05	459	293	17	69	505	74	503	2e-16	93.6
rs:WP_005154109	topoisomerase I [Shigella sonnei].	24.54	542	317	21	7	505	6	498	2e-16	93.6
tr:A0A085UHC4_9STAP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KFE42587.1};	29.62	260	151	11	1	245	1	243	2e-16	89.7
rs:WP_023937657	DNA topoisomerase I [Porphyromonas crevioricanis].	24.28	523	312	17	7	504	6	469	2e-16	93.6
rs:WP_024212414	MULTISPECIES: DNA topoisomerase I [Escherichia].	24.77	537	322	21	7	505	6	498	2e-16	93.6
rs:WP_005137003	topoisomerase I [Shigella sonnei].	24.54	542	317	21	7	505	6	498	2e-16	93.6
tr:A0A0D1PJJ0_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.23	549	328	17	7	505	2	512	2e-16	93.6
rs:WP_033145741	DNA topoisomerase I [Enterobacter cloacae].	24.20	533	330	18	7	505	6	498	2e-16	93.6
rs:WP_027390823	DNA topoisomerase I [Chrysiogenes arsenatis].	23.96	551	328	20	1	512	1	499	2e-16	93.2
rs:WP_021071562	DNA topoisomerase I [Sphingobacterium paucimobilis].	26.15	455	256	18	89	505	59	471	2e-16	93.2
rs:WP_038522534	DNA topoisomerase I [Lactobacillus sp. wkB8].	23.52	523	325	17	7	505	15	486	2e-16	93.2
rs:WP_013172665	DNA topoisomerase I [[Bacillus] selenitireducens].	24.24	524	323	17	7	505	6	480	2e-16	93.2
rs:WP_002503404	DNA topoisomerase I [Staphylococcus epidermidis].	24.81	528	312	18	7	504	6	478	2e-16	93.2
tr:X2NB55_SALEN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.19	146	96	3	315	459	2	145	2e-16	87.8
rs:WP_009501685	DNA topoisomerase I subunit omega [Moraxella macacae].	25.00	436	282	14	88	505	128	536	2e-16	93.6
rs:WP_041725675	DNA topoisomerase I [Caldicellulosiruptor lactoaceticus].	23.47	571	342	21	7	553	6	505	2e-16	93.2
rs:WP_031910262	DNA topoisomerase III, partial [Staphylococcus aureus].	27.35	234	152	6	7	238	5	222	2e-16	89.7
rs:WP_017471872	DNA topoisomerase I [Amphibacillus jilinensis].	26.34	429	259	15	109	505	79	482	2e-16	93.2
rs:WP_031627730	DNA topoisomerase I [Pseudomonas sp. 2_1_26].	25.15	497	295	19	86	553	58	506	2e-16	93.2
rs:WP_031834509	DNA topoisomerase III, partial [Staphylococcus aureus].	31.87	182	114	5	5	180	3	180	2e-16	88.6
rs:WP_014838214	topoisomerase I [Klebsiella oxytoca].	24.58	537	323	19	7	505	6	498	2e-16	93.6
rs:WP_019234829	DNA topoisomerase I [Legionella anisa].	25.61	535	316	17	7	505	6	494	2e-16	93.2
rs:WP_023104979	DNA topoisomerase I [Pseudomonas aeruginosa].	24.95	497	296	19	86	553	58	506	2e-16	93.2
rs:WP_008789958	MULTISPECIES: DNA topoisomerase I [Coprobacillus].	24.23	520	325	19	101	596	74	548	2e-16	93.2
rs:WP_012009947	DNA topoisomerase I [Bacillus pumilus].	26.60	421	259	14	112	504	82	480	2e-16	93.2
rs:WP_001286967	DNA topoisomerase I [Bacillus cereus].	26.37	421	262	15	112	505	82	481	2e-16	93.2
rs:WP_043016148	DNA topoisomerase I [Citrobacter freundii].	24.30	535	327	19	7	505	6	498	2e-16	93.6
rs:WP_009112799	topoisomerase I [Brenneria sp. EniD312].	26.36	440	274	16	88	505	87	498	2e-16	93.6
rs:WP_025368922	DNA topoisomerase I [Buchnera aphidicola].	24.33	563	339	23	7	544	6	506	2e-16	93.6
rs:WP_001433303	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	2e-16	93.6
rs:WP_005619805	DNA topoisomerase I subunit omega [Ruegeria mobilis].	25.26	570	306	26	4	510	1	513	2e-16	93.6
rs:WP_002446285	DNA topoisomerase I [Staphylococcus epidermidis].	24.67	527	314	18	7	504	6	478	2e-16	93.2
rs:WP_039794607	DNA topoisomerase I [Nocardia araoensis].	24.79	593	343	22	7	550	19	557	2e-16	93.6
rs:WP_010595034	MULTISPECIES: DNA topoisomerase I [Rhodococcus].	24.10	585	351	20	7	550	19	551	2e-16	93.6
rs:WP_033944334	DNA topoisomerase I [Pseudomonas aeruginosa].	24.95	497	296	19	86	553	58	506	2e-16	92.8
rs:YP_029935	DNA topoisomerase I [Bacillus anthracis str. Sterne].	26.37	421	262	15	112	505	82	481	2e-16	93.2
rs:WP_005248447	DNA topoisomerase I [Rhodococcus opacus].	25.21	591	337	22	7	550	23	555	2e-16	93.6
rs:WP_001643336	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	2e-16	93.2
rs:WP_019165481	DNA topoisomerase I [Staphylococcus delphini].	25.00	528	311	21	7	504	6	478	2e-16	93.2
tr:W1E0K2_KLEPN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.49	535	326	21	7	505	6	498	2e-16	92.8
rs:WP_029880927	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	25.09	534	308	21	7	505	6	482	2e-16	93.2
rs:WP_011775956	DNA topoisomerase I [Arthrobacter aurescens].	25.36	548	319	19	7	505	12	518	2e-16	93.6
rs:WP_045360425	DNA topoisomerase I [Enterobacter aerogenes].	24.58	537	323	19	7	505	6	498	2e-16	93.2
rs:WP_046640933	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	2e-16	93.2
tr:Q3MN56_LACPA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.56	312	199	10	306	603	4	302	2e-16	91.3
rs:WP_037545865	DNA topoisomerase I [Staphylococcus lugdunensis].	26.85	432	252	16	107	504	77	478	2e-16	93.2
rs:WP_026674294	DNA topoisomerase I [Bacillus bogoriensis].	25.38	528	312	19	7	504	6	481	2e-16	93.2
rs:WP_020621258	DNA topoisomerase I [Cohnella laeviribosi].	25.80	438	282	13	92	504	62	481	2e-16	93.2
rs:WP_046651444	DNA topoisomerase I [Corynebacterium xerosis].	25.74	474	281	18	86	505	75	531	2e-16	93.6
rs:WP_035344662	DNA topoisomerase I [Acholeplasma modicum].	25.43	523	306	21	7	506	6	467	2e-16	92.8
tr:A0A0B7MJT6_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.37	536	311	22	1	504	1	479	2e-16	93.2
rs:WP_034353657	DNA topoisomerase I [Helicobacter sp. MIT 09-6949].	24.29	531	317	21	7	505	5	482	2e-16	93.2
rs:WP_027623453	DNA topoisomerase I [Clostridium lundense].	24.57	529	314	21	7	504	6	480	2e-16	93.2
rs:WP_021572102	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	2e-16	93.2
rs:WP_031786154	DNA topoisomerase III, partial [Staphylococcus aureus].	27.35	234	152	6	7	238	5	222	2e-16	89.7
rs:WP_003120981	DNA topoisomerase I [Pseudomonas aeruginosa].	25.31	478	287	18	99	553	76	506	2e-16	92.8
rs:WP_011097448	DNA topoisomerase I [Chlamydophila abortus].	23.53	595	351	23	7	563	6	534	2e-16	93.2
rs:WP_001678703	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	2e-16	93.2
rs:WP_003935250	DNA topoisomerase I subunit omega [Rhodococcus ruber].	24.10	585	351	20	7	550	19	551	2e-16	93.6
rs:WP_017033749	topoisomerase I [Vibrio genomosp. F10].	23.72	548	319	21	7	505	6	503	2e-16	93.2
rs:WP_001681014	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	2e-16	93.2
rs:WP_004093343	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	2e-16	93.2
tr:G9Z6S3_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.49	535	326	20	7	505	18	510	2e-16	93.2
rs:WP_017548529	DNA topoisomerase I [Salinicoccus carnicancri].	25.71	424	269	15	107	505	77	479	2e-16	93.2
tr:A0A0D6QN89_9DELT	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:GAO04267.1};	23.34	557	323	20	2	505	45	550	2e-16	93.2
rs:WP_033946933	DNA topoisomerase I [Pseudomonas aeruginosa].	25.15	497	295	20	86	553	58	506	2e-16	92.8
rs:WP_038257868	DNA topoisomerase I [Yokenella regensburgei].	24.11	535	328	19	7	505	6	498	2e-16	93.2
rs:WP_001669681	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	2e-16	93.2
rs:WP_001298801	topoisomerase I [Escherichia coli].	24.26	540	321	20	7	505	6	498	2e-16	93.2
rs:WP_016525066	DNA topoisomerase I [Treponema maltophilum].	25.38	528	312	20	5	504	9	482	2e-16	93.2
rs:WP_003320692	DNA topoisomerase I [Bacillus alcalophilus].	24.33	526	319	19	7	504	6	480	2e-16	93.2
rs:WP_017796659	DNA topoisomerase I [Oceanobacillus kimchii].	26.82	425	256	15	112	505	82	482	2e-16	93.2
rs:WP_001286968	DNA topoisomerase I [Bacillus thuringiensis].	26.37	421	262	15	112	505	82	481	2e-16	93.2
rs:WP_006564301	DNA topoisomerase I [Helicobacter suis].	25.11	466	281	16	89	505	64	510	2e-16	93.2
rs:WP_034913033	DNA topoisomerase I [Gilliamella apicola].	24.89	446	273	16	88	505	89	500	2e-16	93.2
rs:WP_004970853	topoisomerase I [Shigella boydii].	24.35	542	318	21	7	505	6	498	2e-16	93.2
rs:WP_018932685	DNA topoisomerase I [Gracilibacillus lacisalsi].	24.33	526	322	16	7	505	6	482	2e-16	92.8
rs:WP_040572020	DNA topoisomerase I [Shewanella benthica].	23.06	542	334	19	7	505	6	507	2e-16	93.2
rs:WP_041727195	DNA topoisomerase I [Caldicellulosiruptor bescii].	23.29	571	343	21	7	553	6	505	2e-16	92.8
tr:W1GKJ1_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.63	536	324	21	7	505	6	498	2e-16	92.8
rs:WP_001383172	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	2e-16	93.2
tr:H1PLC7_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.43	526	306	21	5	504	21	491	2e-16	92.8
rs:WP_002476657	DNA topoisomerase I [Staphylococcus epidermidis].	24.81	528	312	18	7	504	6	478	2e-16	92.8
rs:WP_015366223	DNA topoisomerase I [Enterobacter aerogenes].	24.58	537	323	19	7	505	6	498	2e-16	93.2
rs:WP_009177887	DNA topoisomerase I [Silicibacter sp. TrichCH4B].	25.26	570	306	26	4	510	1	513	2e-16	93.2
rs:WP_038332922	DNA topoisomerase I [Empedobacter falsenii].	24.62	520	309	20	7	504	6	464	2e-16	93.2
rs:WP_001593985	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	2e-16	93.2
rs:WP_046976139	DNA topoisomerase I [Photorhabdus temperata].	24.95	461	292	17	69	505	68	498	2e-16	93.2
rs:WP_011304445	DNA topoisomerase I [Ehrlichia canis].	25.55	548	319	22	4	510	1	500	2e-16	93.2
rs:WP_046900255	DNA topoisomerase I [Gluconobacter oxydans].	26.18	550	309	27	7	510	5	503	2e-16	93.2
rs:WP_018981455	topoisomerase I [Salinimonas chungwhensis].	24.95	541	324	20	7	505	6	506	2e-16	93.2
rs:WP_015492626	Topoisomerase IA [Thermoplasmatales archaeon BRNA1].	22.22	540	349	17	4	532	16	495	2e-16	93.2
rs:WP_023129305	DNA topoisomerase I [Pseudomonas aeruginosa].	25.15	497	295	20	86	553	58	506	2e-16	92.8
rs:WP_005977801	DNA topoisomerase I [Ruegeria lacuscaerulensis].	24.82	564	305	24	4	505	1	507	2e-16	93.2
rs:WP_033963406	DNA topoisomerase I [Pseudomonas aeruginosa].	25.05	495	298	19	86	553	58	506	2e-16	92.8
tr:A0A0C1R6M7_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.34	438	276	14	97	504	72	488	3e-16	92.8
rs:WP_041981348	DNA topoisomerase I [Xenorhabdus nematophila].	25.86	464	284	20	69	505	68	498	3e-16	93.2
rs:WP_025324779	DNA topoisomerase I [Pseudomonas aeruginosa].	25.15	497	295	20	86	553	58	506	3e-16	92.8
rs:WP_041497609	DNA topoisomerase I, partial [Staphylococcus aureus].	27.38	442	267	18	93	505	23	439	3e-16	92.8
rs:WP_039211367	DNA topoisomerase I [Brevibacterium linens].	25.09	546	327	16	7	505	12	522	3e-16	93.2
rs:WP_007560996	DNA topoisomerase III [Bacteroides plebeius].	21.53	562	360	18	4	536	1	510	3e-16	92.8
rs:WP_035168545	MULTISPECIES: DNA topoisomerase I [Caldicellulosiruptor].	23.47	571	342	21	7	553	6	505	3e-16	92.8
tr:C3F5U4_BACTU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.37	421	262	15	112	505	75	474	3e-16	92.8
rs:WP_037203507	MULTISPECIES: DNA topoisomerase I [Rhodococcus].	25.21	591	337	22	7	550	23	555	3e-16	93.2
rs:WP_046822586	DNA topoisomerase I [Clostridium sp. JC272].	25.14	525	315	22	7	504	6	479	3e-16	92.8
rs:WP_014070501	topoisomerase I [Enterobacter asburiae].	24.54	538	322	20	7	505	6	498	3e-16	93.2
rs:WP_028126135	DNA topoisomerase I [Escherichia coli].	24.26	540	321	20	7	505	6	498	3e-16	93.2
rs:WP_024071957	DNA topoisomerase I [Ehrlichia muris].	26.07	537	313	21	4	504	1	489	3e-16	93.2
rs:WP_002496234	DNA topoisomerase I [Staphylococcus epidermidis].	24.67	527	314	18	7	504	6	478	3e-16	92.8
tr:E4S8P0_CALKI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.47	571	342	21	7	553	5	504	3e-16	92.8
rs:WP_033089386	hypothetical protein, partial [Nocardia seriolae].	24.83	592	341	22	7	550	26	561	3e-16	93.2
rs:WP_034029993	DNA topoisomerase I [Pseudomonas aeruginosa].	25.15	497	295	20	86	553	58	506	3e-16	92.8
rs:WP_001497537	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	3e-16	93.2
rs:WP_014124944	DNA topoisomerase I [Tetragenococcus halophilus].	24.43	524	323	18	7	505	7	482	3e-16	92.8
tr:A0A0C7SBB9_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.61	573	332	20	7	553	6	504	3e-16	92.8
rs:WP_043884230	DNA topoisomerase I, partial [Caldanaerobacter subterraneus].	25.00	524	319	19	7	504	6	481	3e-16	92.0
rs:WP_023102685	DNA topoisomerase I [Pseudomonas aeruginosa].	25.21	476	290	17	99	553	76	506	3e-16	92.8
rs:WP_041455453	DNA topoisomerase I [Anaerolinea thermophila].	21.96	592	356	21	7	559	2	526	3e-16	92.8
tr:C2VXP8_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.37	421	262	15	112	505	52	451	3e-16	92.8
rs:WP_035176689	DNA topoisomerase [Acidobacteria bacterium KBS 146].	23.59	585	319	24	7	510	6	543	3e-16	93.2
rs:WP_034732693	DNA topoisomerase I [Idiomarina sp. MCCC 1A10513].	23.73	531	342	19	7	505	6	505	3e-16	93.2
tr:B9MM33_CALBD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.29	571	343	21	7	553	5	504	3e-16	92.8
rs:WP_003050739	DNA topoisomerase I [Streptococcus dysgalactiae].	23.99	521	320	16	7	504	24	491	3e-16	92.8
tr:A0A0D6S764_BACMY	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KIV64387.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIV64387.1};	28.18	291	195	7	260	539	7	294	3e-16	92.8
rs:WP_011048772	DNA topoisomerase I [Ruegeria pomeroyi].	24.57	578	312	26	4	510	1	525	3e-16	93.2
rs:WP_024962665	DNA topoisomerase I [Campylobacter ureolyticus].	24.08	519	324	17	7	505	5	473	3e-16	92.8
rs:WP_029377477	DNA topoisomerase I [Staphylococcus xylosus].	25.19	524	314	20	7	504	6	477	3e-16	92.8
rs:WP_046836243	DNA topoisomerase I [Staphylococcus succinus].	25.14	525	315	20	7	505	6	478	3e-16	92.8
rs:WP_039683338	DNA topoisomerase I [Tateyamaria sp. ANG-S1].	24.77	533	319	19	4	505	1	482	3e-16	93.2
rs:WP_038551051	DNA topoisomerase I [Corynebacterium glyciniphilum].	26.28	487	281	21	80	505	71	540	3e-16	93.2
rs:WP_017365594	DNA topoisomerase I [Methylococcus capsulatus].	24.79	589	343	20	7	562	6	527	3e-16	92.8
rs:WP_001663866	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	93.2
rs:WP_001592150	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	93.2
rs:WP_001468644	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	3e-16	93.2
rs:WP_032464379	DNA topoisomerase I [Streptococcus pyogenes].	23.61	521	322	16	7	504	29	496	3e-16	92.8
rs:WP_034038659	DNA topoisomerase I [Pseudomonas aeruginosa].	24.95	497	296	19	86	553	58	506	3e-16	92.8
rs:WP_007298531	DNA topoisomerase I [Rhodococcus imtechensis].	25.21	591	337	22	7	550	23	555	3e-16	93.2
rs:WP_043928301	DNA topoisomerase I [Bacillus licheniformis].	24.67	531	321	19	112	607	82	568	3e-16	92.8
rs:WP_020451381	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.43	528	326	19	112	607	82	568	3e-16	92.8
rs:WP_039064846	DNA topoisomerase I [Shigella flexneri].	23.93	535	329	19	7	505	6	498	3e-16	93.2
rs:WP_004991834	topoisomerase I [Shigella boydii].	24.35	542	318	21	7	505	6	498	3e-16	93.2
tr:F4VBV2_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.35	542	318	21	7	505	20	512	3e-16	93.2
tr:A9EHJ0_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.06	542	334	19	7	505	22	523	3e-16	93.2
rs:WP_026898152	DNA topoisomerase I [Pedobacter oryzae].	24.50	453	267	15	89	505	59	472	3e-16	93.2
tr:J8T6M4_PASMD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	37.59	141	81	5	210	346	1	138	3e-16	87.0
rs:WP_005998667	DNA topoisomerase I [Desulfuromonas acetoxidans].	25.09	538	316	19	7	505	6	495	3e-16	92.8
rs:WP_036609379	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	24.81	532	312	21	7	505	6	482	3e-16	92.8
rs:WP_023273414	DNA topoisomerase I [Acinetobacter nectaris].	24.95	541	317	21	7	505	26	519	3e-16	93.2
rs:WP_007669468	DNA topoisomerase I [alpha proteobacterium BAL199].	24.63	544	310	22	7	505	5	493	3e-16	93.2
rs:WP_038465909	DNA topoisomerase I [Arthrobacter sp. PAMC25486].	25.32	549	322	20	7	505	17	527	3e-16	93.2
rs:WP_044067989	DNA topoisomerase III, partial [Escherichia coli].	25.17	294	202	8	8	292	5	289	3e-16	89.7
rs:WP_045894874	DNA topoisomerase I [Escherichia coli].	24.30	535	327	20	7	505	6	498	3e-16	93.2
rs:WP_023045298	topoisomerase I [Photorhabdus temperata].	24.95	461	292	17	69	505	68	498	3e-16	93.2
rs:WP_023787408	DNA topoisomerase I [Hyphomicrobium nitrativorans].	24.32	555	318	22	4	505	1	506	3e-16	93.2
rs:WP_007128765	DNA topoisomerase I [Paenibacillus lactis].	24.43	528	317	20	7	504	6	481	3e-16	92.8
rs:WP_002480688	DNA topoisomerase 1 [Staphylococcus simulans].	24.29	527	315	20	7	504	6	477	3e-16	92.8
rs:WP_034021225	DNA topoisomerase I [Pseudomonas aeruginosa].	25.15	497	295	20	86	553	58	506	3e-16	92.8
rs:WP_028078437	DNA topoisomerase I [Solobacterium moorei].	23.59	568	333	21	7	549	5	496	3e-16	92.8
rs:WP_033500972	DNA topoisomerase III, partial [Bifidobacterium kashiwanohense].	29.50	322	165	15	307	579	11	319	3e-16	92.0
rs:WP_022183068	DNA topoisomerase [Clostridium sp. CAG:575].	23.86	528	319	19	7	504	6	480	3e-16	92.8
rs:WP_039294073	DNA topoisomerase I [Cedecea neteri].	24.78	464	299	16	64	505	63	498	3e-16	93.2
rs:WP_001573409	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	93.2
rs:WP_001372673	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	93.2
rs:WP_016520265	DNA topoisomerase I [Treponema socranskii].	24.20	533	312	20	5	504	16	489	3e-16	92.8
rs:WP_045181206	DNA topoisomerase I [Staphylococcus aureus].	25.76	528	309	22	7	505	6	479	3e-16	92.8
rs:WP_032257049	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	93.2
rs:WP_001373327	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	93.2
rs:WP_039295145	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	24.81	528	315	21	7	504	6	481	3e-16	92.8
tr:A0A090NCS4_SHIDY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.35	542	318	21	7	505	20	512	3e-16	93.2
rs:WP_044330667	DNA topoisomerase I [Bacillus safensis].	25.05	531	319	20	112	607	82	568	3e-16	92.8
rs:WP_001394200	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_001355506	DNA topoisomerase I subunit omega [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_024551692	DNA topoisomerase I [Cronobacter helveticus].	24.02	533	332	17	7	505	6	499	3e-16	92.8
rs:WP_022260022	DNA topoisomerase [Eubacterium sp. CAG:251].	27.77	443	260	17	97	505	66	482	3e-16	92.8
rs:WP_031868161	DNA topoisomerase I [Staphylococcus aureus].	27.38	442	267	18	93	505	63	479	3e-16	92.8
rs:WP_031447743	DNA topoisomerase I [Caulobacteraceae bacterium PMMR1].	23.49	562	319	21	4	510	1	506	3e-16	93.2
rs:WP_044702697	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_044808717	DNA topoisomerase I [Escherichia coli].	24.30	535	327	20	7	505	6	498	3e-16	92.8
rs:WP_021550866	DNA topoisomerase 1 [Escherichia coli].	24.77	537	322	21	7	505	6	498	3e-16	92.8
rs:WP_001286965	DNA topoisomerase I [Bacillus cereus].	26.37	421	262	15	112	505	82	481	3e-16	92.8
rs:WP_004998368	topoisomerase I [Shigella boydii].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_025044027	DNA topoisomerase I [Sulfitobacter sp. MM-124].	26.26	537	305	23	4	505	1	481	3e-16	93.2
rs:WP_001646990	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	3e-16	92.8
rs:WP_040765487	DNA topoisomerase III, partial [Sutterella parvirubra].	29.33	225	144	6	315	531	4	221	3e-16	92.4
rs:WP_034662386	DNA topoisomerase I [Bacillus pumilus].	26.13	421	261	13	112	504	82	480	3e-16	92.8
rs:WP_044721998	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
tr:B7R9S8_9THEO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.00	524	319	19	7	504	24	499	3e-16	92.0
rs:WP_026821992	DNA topoisomerase I [Arsenophonus nasoniae].	23.64	533	330	17	7	504	6	496	3e-16	92.8
tr:A0A0E0W3G8_BACAN	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:AFH85168.1};	26.37	421	262	15	112	505	41	440	3e-16	92.4
tr:M5AH10_LACBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.84	313	200	10	306	603	4	302	3e-16	91.3
rs:WP_001347791	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_045433809	DNA topoisomerase I [Mycoplasma canadense].	25.19	528	297	22	7	504	6	465	3e-16	92.4
rs:WP_037228878	DNA topoisomerase I [Rhodococcus wratislaviensis].	25.21	591	337	22	7	550	23	555	3e-16	93.2
rs:WP_047071578	DNA topoisomerase I [Enterobacter asburiae].	24.77	541	317	21	7	505	6	498	3e-16	92.8
rs:WP_046481020	DNA topoisomerase I [Citrobacter amalonaticus].	24.49	535	326	19	7	505	6	498	3e-16	92.8
rs:WP_001704495	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	3e-16	92.8
rs:XP_011652536	PREDICTED: uncharacterized protein LOC101210581 [Cucumis sativus].	25.66	534	293	22	47	510	353	852	3e-16	93.2
rs:WP_011909276	DNA topoisomerase I [Rhodobacter sphaeroides].	24.82	544	320	25	4	510	1	492	3e-16	92.8
rs:WP_042575756	DNA topoisomerase I [Rhodococcus sp. MEB064].	25.00	588	342	22	7	550	21	553	3e-16	93.2
rs:WP_047091085	DNA topoisomerase I, partial [Escherichia coli].	24.82	544	313	22	7	505	6	498	3e-16	92.8
rs:WP_016884539	DNA topoisomerase I [Rhodococcus sp. DK17].	25.21	591	337	22	7	550	23	555	3e-16	93.2
sp:TOP1_ECOLI	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.35	542	318	21	7	505	6	498	3e-16	92.8
tr:A0A0A0F9H1_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.35	542	318	21	7	505	20	512	3e-16	92.8
rs:WP_002489763	DNA topoisomerase I [Staphylococcus epidermidis].	24.81	528	312	19	7	504	6	478	3e-16	92.4
rs:WP_032352450	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_043972525	DNA topoisomerase I [Novosphingobium sp. P6W].	26.41	549	294	26	7	510	4	487	3e-16	92.8
rs:WP_045639399	DNA topoisomerase I [Flavobacteriales bacterium BRH_c54].	23.36	518	319	17	7	504	6	465	3e-16	92.8
rs:WP_018052407	hypothetical protein [Marinimicrobia bacterium SCGC AB-629-J13].	25.05	543	324	23	1	504	1	499	3e-16	92.8
rs:WP_001726005	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_001541847	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
tr:D6HW37_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.35	542	318	21	7	505	8	500	3e-16	92.8
rs:WP_001382110	topoisomerase I [Escherichia coli].	24.26	540	321	20	7	505	6	498	3e-16	92.8
rs:WP_014922671	DNA topoisomerase I [Arthrobacter sp. Rue61a].	25.36	548	319	19	7	505	12	518	3e-16	92.8
rs:WP_020301296	DNA topoisomerase I [Pseudomonas sp. CF150].	25.62	484	306	18	43	504	30	481	3e-16	92.0
rs:WP_032191162	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_023330550	MULTISPECIES: DNA topoisomerase 1 [Enterobacter].	24.63	540	319	20	7	505	6	498	3e-16	92.8
rs:WP_042203615	DNA topoisomerase I [Escherichia coli].	24.30	535	327	20	7	505	6	498	3e-16	92.8
rs:WP_028518733	DNA topoisomerase I [Ruminococcus flavefaciens].	26.00	527	312	20	7	505	5	481	3e-16	92.4
rs:WP_043597838	DNA topoisomerase I [Aeromonas diversa].	22.40	634	392	23	7	599	6	580	3e-16	92.8
rs:WP_018021499	DNA topoisomerase I [Corynebacterium doosanense].	24.78	561	315	23	5	505	11	524	3e-16	92.8
rs:WP_032642185	DNA topoisomerase I [Enterobacter sp. EGD-HP1].	24.54	538	322	20	7	505	6	498	3e-16	92.8
rs:WP_032206808	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
tr:G1FGU3_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.27	467	296	17	80	505	48	502	3e-16	92.8
rs:WP_016709380	topoisomerase I [Pseudoalteromonas haloplanktis].	25.00	436	285	15	88	505	96	507	3e-16	92.8
rs:WP_034031775	DNA topoisomerase I [Pseudomonas aeruginosa].	24.85	499	294	20	86	553	58	506	3e-16	92.4
rs:WP_047109379	DNA topoisomerase I [Vibrio vulnificus].	24.67	458	296	16	69	505	74	503	3e-16	92.8
rs:WP_040089153	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_032221027	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_001428676	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_003915304	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_045281238	DNA topoisomerase I [Enterobacter sp. 44593].	24.63	540	319	20	7	505	6	498	3e-16	92.8
rs:WP_009121355	DNA topoisomerase III [Bacteroides clarus].	22.12	529	339	20	4	498	1	490	3e-16	92.4
tr:A0A098ED90_9ZZZZ	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:CEG13983.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CEG13983.1};	29.59	294	176	11	170	449	32	308	3e-16	90.1
rs:WP_005587787	DNA topoisomerase I [Clostridium ultunense].	24.52	624	372	23	7	599	6	561	3e-16	92.4
rs:WP_035463685	DNA topoisomerase I [Lactobacillus ceti].	25.24	523	313	21	8	504	1	471	3e-16	92.4
rs:WP_023104007	DNA topoisomerase I [Pseudomonas aeruginosa].	25.15	497	295	20	86	553	58	506	3e-16	92.4
rs:WP_039444195	DNA topoisomerase I [Vibrio navarrensis].	23.57	454	306	13	69	505	74	503	3e-16	92.8
rs:WP_011080010	topoisomerase I [Vibrio vulnificus].	24.67	458	296	16	69	505	74	503	3e-16	92.8
rs:WP_045149545	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_001391746	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
tr:E8N5B1_ANATU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.96	592	356	21	7	559	73	597	3e-16	92.8
rs:WP_024246437	DNA topoisomerase I [Escherichia coli].	24.77	537	322	21	7	505	6	498	3e-16	92.8
rs:WP_027663457	DNA topoisomerase I [Escherichia coli].	24.26	540	321	20	7	505	6	498	3e-16	92.8
rs:WP_001466145	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_047085249	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_005515801	DNA topoisomerase I [Rhodococcus equi].	24.70	587	345	21	7	550	19	551	3e-16	92.8
rs:WP_013414752	DNA topoisomerase I [Rhodococcus equi].	24.70	587	345	21	7	550	19	551	3e-16	92.8
rs:WP_032092645	DNA topoisomerase I [Necropsobacter rosorum].	25.11	450	287	17	79	505	82	504	3e-16	92.8
rs:WP_018046902	hypothetical protein [Nitrospina sp. AB-629-B06].	25.05	547	320	21	7	513	42	538	3e-16	92.8
rs:WP_021676309	toprim domain protein, partial [Peptostreptococcaceae bacterium oral taxon 113].	33.49	212	122	10	5	213	3	198	3e-16	88.2
rs:WP_001591966	DNA topoisomerase 1 [Escherichia coli].	24.40	541	319	21	7	505	6	498	3e-16	92.8
rs:WP_001396571	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_015503574	topoisomerase I - like protein [Pseudomonas aeruginosa].	25.05	495	298	19	86	553	58	506	3e-16	92.4
rs:WP_032179017	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_044325484	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_013604174	DNA topoisomerase [Vulcanisaeta moutnovskia].	22.79	544	347	25	15	537	26	517	3e-16	92.4
rs:WP_005062053	topoisomerase I [Shigella flexneri].	23.99	542	320	20	7	505	6	498	3e-16	92.8
rs:WP_045152100	DNA topoisomerase I [Escherichia coli].	24.54	542	314	21	7	505	6	495	3e-16	92.8
rs:WP_039303632	DNA topoisomerase I [Cedecea neteri].	25.00	460	303	15	64	505	63	498	3e-16	92.8
rs:WP_011184520	DNA topoisomerase I [Streptococcus pyogenes].	23.61	521	322	16	7	504	29	496	3e-16	92.4
rs:WP_045716257	DNA topoisomerase I, partial [Salmonella enterica].	25.60	496	282	19	7	470	6	446	3e-16	91.3
tr:X5DQT1_9CORY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.28	487	281	21	80	505	91	560	3e-16	92.8
rs:WP_001682840	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_001599360	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	3e-16	92.8
rs:WP_033808261	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	3e-16	92.8
rs:WP_036889217	DNA topoisomerase I, partial [Prevotella aurantiaca].	26.02	342	212	10	5	333	3	316	3e-16	89.7
tr:A5IKG3_THEP1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.41	551	322	20	7	544	9	483	3e-16	92.4
rs:WP_001619376	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_013184437	topoisomerase I [Xenorhabdus nematophila].	26.08	464	283	20	69	505	68	498	3e-16	92.8
rs:WP_017799901	topoisomerase I [Erwinia toletana].	24.89	458	296	15	69	505	69	499	3e-16	92.8
tr:J1RFB0_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.21	591	337	22	7	550	1	533	3e-16	92.8
tr:A0A0A8KSB6_LACFE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.47	523	318	21	7	504	29	499	3e-16	92.4
rs:WP_038051617	DNA topoisomerase I [Thermotoga sp. Mc24].	25.41	551	322	20	7	544	9	483	3e-16	92.4
rs:WP_012421655	MULTISPECIES: DNA topoisomerase 1 [Shigella].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_001684861	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_001698309	DNA topoisomerase I [Escherichia coli].	24.72	542	316	21	7	505	6	498	3e-16	92.8
rs:WP_001698223	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
rs:WP_032084999	DNA topoisomerase I, partial [Escherichia coli].	24.35	542	318	21	7	505	6	498	3e-16	92.8
tr:V9QQE9_9PSED	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.90	514	320	18	43	539	43	507	4e-16	92.4
rs:WP_008437341	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	25.10	514	319	19	43	539	30	494	4e-16	92.4
rs:WP_039679626	DNA topoisomerase I [Terrisporobacter othiniensis].	26.32	570	330	25	5	553	4	504	4e-16	92.4
rs:WP_022684221	DNA topoisomerase I [Sphingobium sp. YL23].	25.05	523	316	20	7	505	4	474	4e-16	92.8
rs:WP_028131801	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_024234990	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_021552277	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_006934918	DNA topoisomerase I [Labrenzia aggregata].	25.70	568	306	28	4	512	1	511	4e-16	92.8
rs:WP_017030334	topoisomerase I [Vibrio breoganii].	24.51	457	298	17	69	505	74	503	4e-16	92.8
rs:WP_036887869	DNA topoisomerase I, partial [Prevotella bivia].	25.66	343	220	11	5	333	3	324	4e-16	89.7
tr:L2TJV5_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.21	591	337	22	7	550	1	533	4e-16	92.8
rs:WP_034949065	DNA topoisomerase I [Erwinia oleae].	26.38	436	258	17	99	505	97	498	4e-16	92.8
rs:WP_022571625	DNA topoisomerase I [Rhodobacteraceae bacterium HIMB11].	25.73	548	312	24	4	510	1	494	4e-16	92.8
rs:WP_025759091	DNA topoisomerase I [Shigella flexneri].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_015697113	topoisomerase I [Rahnella aquatilis].	25.63	437	281	15	88	505	87	498	4e-16	92.8
rs:WP_033714662	DNA topoisomerase III, partial [Bacillus cereus].	31.32	182	113	6	7	182	5	180	4e-16	88.2
rs:WP_005068394	topoisomerase I [Shigella flexneri].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_016179974	DNA topoisomerase 1 [Enterococcus avium].	23.96	530	316	19	7	504	7	481	4e-16	92.4
rs:WP_003059104	DNA topoisomerase I, partial [Streptococcus dysgalactiae].	24.10	502	318	16	26	504	2	463	4e-16	92.4
rs:WP_000513603	DNA topoisomerase I subunit omega, partial [Escherichia coli].	24.67	535	325	20	7	505	6	498	4e-16	92.4
rs:WP_013079883	DNA topoisomerase I [Caulobacter segnis].	25.05	547	320	24	4	510	1	497	4e-16	92.8
rs:WP_023335949	DNA topoisomerase 1 [Enterobacter sp. MGH 24].	24.44	540	320	20	7	505	6	498	4e-16	92.8
rs:WP_046932689	hypothetical protein [Xanthomonas perforans].	23.56	539	317	17	5	505	3	484	4e-16	92.4
rs:WP_047338534	DNA topoisomerase I [Enterococcus cecorum].	23.47	524	326	18	7	504	7	481	4e-16	92.4
rs:WP_042362837	DNA topoisomerase I [Staphylococcus xylosus].	25.19	524	314	20	7	504	6	477	4e-16	92.4
rs:WP_034167620	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_039263555	MULTISPECIES: DNA topoisomerase I [Enterobacter].	23.83	533	332	17	7	505	6	498	4e-16	92.8
rs:WP_001295576	MULTISPECIES: DNA topoisomerase I [Enterobacteriaceae].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_012667988	topoisomerase I [Erwinia pyrifoliae].	25.98	458	291	16	69	505	68	498	4e-16	92.8
rs:WP_001397166	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_047086937	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_022446921	DNA topoisomerase [Faecalibacterium sp. CAG:74].	25.84	538	303	22	7	505	9	489	4e-16	92.4
rs:WP_009380839	DNA topoisomerase I [Brevibacterium casei].	24.82	544	331	20	7	505	12	522	4e-16	92.8
rs:WP_005074608	topoisomerase I [Shigella flexneri].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_045177202	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_001691736	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_012601486	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_044577397	DNA topoisomerase I [Arthrobacter sp. A3].	25.64	550	319	20	7	505	17	527	4e-16	92.8
rs:WP_028954489	DNA topoisomerase I [Synechocystis sp. PCC 7509].	25.00	464	278	18	107	526	82	519	4e-16	92.4
rs:WP_034428118	DNA topoisomerase, partial [Anaerococcus pacaensis].	26.89	305	187	10	7	307	4	276	4e-16	89.4
rs:WP_039464588	DNA topoisomerase I [Vibrio navarrensis].	23.57	454	306	13	69	505	74	503	4e-16	92.8
rs:WP_001761127	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_040017644	DNA topoisomerase I [Enterobacter ludwigii].	24.39	533	329	19	7	505	6	498	4e-16	92.8
rs:WP_016495870	topoisomerase I [Enterobacter sp. R4-368].	24.21	537	325	19	7	505	6	498	4e-16	92.8
rs:WP_032253403	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	4e-16	92.8
rs:WP_046426265	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_001641657	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_001583462	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_001482712	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	4e-16	92.8
rs:WP_023610295	DNA topoisomerase I [Streptococcus pyogenes].	23.61	521	322	16	7	504	29	496	4e-16	92.4
rs:WP_011378684	DNA topoisomerase I [Shigella dysenteriae].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_009534199	DNA topoisomerase I [Oribacterium parvum].	24.29	527	320	18	7	505	6	481	4e-16	92.4
rs:WP_028399000	DNA topoisomerase I [Bacillus panaciterrae].	26.30	422	260	14	112	505	82	480	4e-16	92.4
rs:WP_014956947	DNA topoisomerase I [Desulfobacula toluolica].	26.91	457	277	18	93	514	63	497	4e-16	92.4
rs:WP_018300335	hypothetical protein [Fangia hongkongensis].	24.44	540	317	20	7	505	6	495	4e-16	92.4
rs:WP_001342100	MULTISPECIES: topoisomerase I [Enterobacteriaceae].	24.35	542	318	21	7	505	6	498	4e-16	92.8
rs:WP_012619491	topoisomerase I [Buchnera aphidicola].	22.66	631	398	24	5	607	4	572	4e-16	92.4
rs:WP_029940950	DNA topoisomerase I, partial [Sphingomonas astaxanthinifaciens].	27.35	446	246	20	107	510	75	484	4e-16	92.4
rs:WP_032280486	DNA topoisomerase 1 [Escherichia coli].	24.30	535	327	20	7	505	6	498	4e-16	92.4
rs:WP_005023339	topoisomerase I [Shigella dysenteriae].	24.35	542	318	21	7	505	6	498	4e-16	92.4
rs:WP_001360019	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.4
rs:WP_026566452	DNA topoisomerase I [Bacillus sp. UNC41MFS5].	26.71	423	257	15	112	504	82	481	4e-16	92.4
rs:WP_018677342	topoisomerase I [Acinetobacter tjernbergiae].	25.17	441	276	15	88	505	108	517	4e-16	92.8
tr:D2TAL0_ERWP6	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.55	458	293	15	69	505	43	473	4e-16	92.4
rs:WP_001361672	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.4
rs:WP_001625658	DNA topoisomerase I [Escherichia coli].	24.72	542	316	21	7	505	6	498	4e-16	92.4
rs:WP_044664589	DNA topoisomerase I [Syntrophaceticus schinkii].	26.23	427	258	16	107	504	77	475	4e-16	92.4
rs:WP_022866500	DNA topoisomerase I [Actinobaculum urinale].	24.73	554	319	22	7	505	5	515	4e-16	92.8
rs:WP_022506394	DNA topoisomerase [Eubacterium sp. CAG:581].	26.14	528	309	21	7	504	5	481	4e-16	92.4
rs:WP_010845973	DNA topoisomerase 1 [Xenorhabdus nematophila].	26.08	464	283	20	69	505	68	498	4e-16	92.4
rs:WP_012017586	topoisomerase I [Enterobacter sp. 638].	24.11	535	328	19	7	505	6	498	4e-16	92.4
rs:WP_042283444	DNA topoisomerase I [Citrobacter sedlakii].	24.07	540	322	20	7	505	6	498	4e-16	92.4
rs:WP_019705470	topoisomerase I [Klebsiella pneumoniae].	24.39	533	329	19	7	505	6	498	4e-16	92.4
rs:WP_001485714	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.4
rs:WP_028954651	DNA topoisomerase I [Sulfitobacter sp. 20_GPM-1509m].	25.50	549	311	24	4	510	1	493	4e-16	92.4
rs:WP_010920309	DNA topoisomerase I [Caulobacter vibrioides].	25.32	553	311	26	4	510	1	497	4e-16	92.4
rs:WP_025648226	DNA topoisomerase I [Clostridium perfringens].	24.76	525	318	20	7	505	6	479	4e-16	92.4
rs:WP_022220378	DNA topoisomerase [Coprococcus comes CAG:19].	24.25	532	316	23	7	504	6	484	4e-16	92.4
rs:WP_011596786	MULTISPECIES: DNA topoisomerase I [Rhodococcus].	25.21	591	337	22	7	550	23	555	4e-16	92.8
rs:WP_044653610	DNA topoisomerase I, partial [Bacteroides acidifaciens].	27.46	295	167	11	137	415	17	280	4e-16	89.4
rs:WP_038289556	DNA topoisomerase I [Zooshikella ganghwensis].	23.45	533	345	19	7	505	6	509	4e-16	92.4
rs:WP_001703146	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.4
rs:WP_023392189	DNA topoisomerase I [Abiotrophia defectiva].	24.32	518	323	18	7	504	7	475	4e-16	92.4
rs:WP_026775681	DNA topoisomerase I [Polaribacter sp. Hel_I_88].	25.53	521	302	20	7	504	6	463	4e-16	92.4
rs:WP_007816808	DNA topoisomerase I [Roseobacter sp. AzwK-3b].	24.62	532	321	19	4	505	1	482	4e-16	92.4
rs:WP_014945663	DNA topoisomerase I [Chlamydia psittaci].	23.77	589	357	22	7	563	6	534	4e-16	92.4
rs:WP_008375020	DNA topoisomerase I [Coprococcus comes].	24.25	532	316	23	7	504	6	484	4e-16	92.4
rs:WP_032169931	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.4
rs:WP_039056062	DNA topoisomerase I [Enterobacter sp. Bisph1].	24.30	535	327	18	7	505	6	498	4e-16	92.4
rs:WP_001423441	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.4
rs:WP_019943304	DNA topoisomerase I [Dyadobacter beijingensis].	24.72	530	298	21	7	505	6	465	4e-16	92.4
rs:WP_009330770	MULTISPECIES: DNA topoisomerase I [Bacillus].	26.19	420	262	15	112	504	82	480	4e-16	92.4
rs:WP_046406360	DNA topoisomerase I [Clostridium sp. A254.MGS-251].	27.77	443	260	17	97	505	66	482	4e-16	92.4
rs:WP_001235858	hypothetical protein, partial [Salmonella enterica].	25.08	295	203	8	8	293	5	290	4e-16	89.4
rs:WP_036178576	hypothetical protein, partial [Lysinibacillus massiliensis].	27.31	227	150	5	333	547	1	224	4e-16	90.5
rs:WP_020240018	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.4
rs:WP_001553967	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.4
rs:WP_004698880	DNA topoisomerase I [Acinetobacter sp. NIPH 973].	23.38	539	326	18	7	505	25	516	4e-16	92.4
tr:K1RSX6_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC46549.1}; Flags: Fragment;	28.12	288	173	9	284	550	7	281	4e-16	91.3
rs:WP_040504074	hypothetical protein, partial [Leucothrix mucor].	24.02	562	318	18	3	505	2	513	4e-16	92.4
rs:WP_002502089	DNA topoisomerase I [Staphylococcus epidermidis].	24.67	527	314	18	7	504	6	478	4e-16	92.4
rs:WP_044864065	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	4e-16	92.4
rs:WP_046128972	DNA topoisomerase I [Bacillus sp. TH008].	24.62	528	325	19	112	607	82	568	4e-16	92.4
rs:WP_022257719	DNA topoisomerase [Faecalibacterium sp. CAG:82].	25.42	531	311	20	7	505	5	482	4e-16	92.4
rs:WP_042101137	DNA topoisomerase I [Escherichia coli].	24.30	535	327	20	7	505	6	498	4e-16	92.4
rs:WP_047066985	DNA topoisomerase I, partial [Enterobacter aerogenes].	24.32	551	329	20	7	513	6	512	4e-16	92.0
rs:WP_012526797	DNA topoisomerase I [Anaeromyxobacter sp. K].	23.87	553	325	21	2	505	45	550	4e-16	92.4
rs:WP_022286039	DNA topoisomerase [Bacteroides sp. CAG:770].	25.24	527	299	22	7	504	76	536	4e-16	92.4
rs:WP_014944633	DNA topoisomerase I [Chlamydia psittaci].	23.77	589	357	22	7	563	6	534	4e-16	92.4
rs:WP_025392403	DNA topoisomerase I [Desulfurella acetivorans].	23.97	634	367	27	7	601	5	562	4e-16	92.4
rs:WP_019167868	DNA topoisomerase I [Staphylococcus intermedius].	25.00	528	311	21	7	504	6	478	4e-16	92.0
rs:WP_016239518	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.4
rs:WP_021580713	DNA topoisomerase 1 [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.4
gp:AJ938182_1074	DNA topoisomerase I [Staphylococcus aureus RF122]	25.76	528	309	22	7	505	8	481	4e-16	92.0
rs:WP_040555347	DNA topoisomerase I, partial [Prevotella disiens].	25.94	347	210	11	7	333	5	324	4e-16	89.7
rs:WP_012766956	DNA topoisomerase I [Streptococcus dysgalactiae].	23.61	521	322	16	7	504	29	496	4e-16	92.4
rs:WP_016981692	DNA topoisomerase I [Chlamydia psittaci].	23.77	589	357	22	7	563	6	534	4e-16	92.4
rs:WP_012580135	DNA topoisomerase I [Thermosipho africanus].	24.87	579	327	21	7	562	8	501	4e-16	92.0
rs:WP_046871126	DNA topoisomerase I [Pediococcus damnosus].	24.62	524	318	22	7	505	25	496	4e-16	92.4
rs:WP_008461318	topoisomerase I [Enterobacter sp. Ag1].	25.00	460	303	15	64	505	63	498	4e-16	92.4
rs:WP_032072733	DNA topoisomerase I TopA [uncultured bacterium].	25.66	452	280	16	81	505	49	471	4e-16	92.0
rs:WP_046510821	DNA topoisomerase I [Salinicoccus sp. SV-16].	25.71	424	269	15	107	505	77	479	4e-16	92.0
rs:WP_014946975	DNA topoisomerase I [Chlamydia psittaci].	23.52	591	356	23	7	563	6	534	4e-16	92.4
rs:WP_045329359	DNA topoisomerase I [Enterobacter asburiae].	24.20	533	330	18	7	505	6	498	4e-16	92.4
rs:WP_042726447	DNA topoisomerase I, partial [Curtobacterium sp. B8].	23.21	560	328	22	7	505	13	531	4e-16	92.0
tr:E1KMG8_9BACT	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EFL47335.1};	25.94	347	210	11	7	333	5	324	4e-16	89.7
tr:X1JH75_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S15831 {ECO:0000313|EMBL:GAH69093.1}; Flags: Fragment;	27.62	286	176	7	73	354	1	259	4e-16	89.0
tr:A0A0C1HCF0_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00046608}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	592	360	22	5	564	17	548	4e-16	92.4
tr:A0A0B8NKQ9_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.83	592	341	22	7	550	1	536	4e-16	92.4
rs:WP_012961976	DNA topoisomerase I [Streptococcus gallolyticus].	24.71	526	310	19	7	504	32	499	4e-16	92.0
rs:WP_043487167	DNA topoisomerase I [Pseudomonas aeruginosa].	25.10	478	288	19	99	553	76	506	4e-16	92.0
rs:WP_032349710	DNA topoisomerase I [Escherichia coli].	25.00	544	312	23	7	505	6	498	4e-16	92.4
rs:WP_001718167	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	4e-16	92.4
rs:WP_010777005	hypothetical protein, partial [Enterococcus faecalis].	32.97	185	111	6	5	182	3	181	4e-16	87.4
tr:A0A076ETH3_RHOOP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.21	591	337	22	7	550	23	555	4e-16	92.4
rs:WP_023289334	MULTISPECIES: DNA topoisomerase 1 [Klebsiella].	24.02	533	331	18	7	505	6	498	4e-16	92.4
rs:WP_013390513	MULTISPECIES: DNA topoisomerase I [Bacillus subtilis group].	25.90	525	306	21	112	599	82	560	4e-16	92.0
rs:WP_004762171	DNA topoisomerase I [Acinetobacter sp. CIP 102129].	24.12	539	323	19	7	505	25	517	4e-16	92.4
rs:WP_013445935	DNA topoisomerase I [Paludibacter propionicigenes].	26.20	523	301	23	7	504	6	468	4e-16	92.4
rs:WP_010890220	hypothetical protein [Streptococcus agalactiae].	31.96	219	130	8	5	215	3	210	4e-16	88.2
rs:WP_019841512	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	4e-16	92.4
rs:WP_034495665	DNA topoisomerase I [Buttiauxella agrestis].	25.00	464	298	16	64	505	63	498	4e-16	92.4
rs:WP_019879161	hypothetical protein [Succinispira mobilis].	25.00	628	365	28	5	598	4	559	4e-16	92.0
rs:WP_001707026	DNA topoisomerase I [Escherichia coli].	25.00	544	312	23	7	505	6	498	4e-16	92.4
rs:WP_033069543	DNA topoisomerase I [Thalassospira australica].	25.32	541	313	22	4	505	1	489	4e-16	92.4
rs:WP_016247142	DNA topoisomerase 1 [Escherichia coli].	24.30	535	327	20	7	505	6	498	4e-16	92.4
rs:WP_000513601	topoisomerase I [Escherichia fergusonii].	24.89	466	296	16	64	505	63	498	4e-16	92.4
rs:WP_001481542	DNA topoisomerase I [Escherichia coli].	24.72	542	316	21	7	505	6	498	4e-16	92.4
rs:WP_012583876	DNA topoisomerase I [Dictyoglomus turgidum].	25.00	556	313	22	1	513	1	495	4e-16	92.0
rs:WP_036891111	DNA topoisomerase I, partial [Prevotella corporis].	26.18	340	210	10	7	333	5	316	4e-16	89.4
rs:WP_015736334	DNA topoisomerase I [Paenibacillus sp. Y412MC10].	24.33	526	320	19	7	504	6	481	4e-16	92.0
rs:WP_039383557	DNA topoisomerase I [Neochlamydia sp. TUME1].	23.65	592	360	22	5	564	4	535	4e-16	92.4
rs:WP_008898159	topoisomerase I [Rheinheimera sp. A13L].	24.67	535	322	20	7	505	6	495	4e-16	92.4
rs:WP_020804553	DNA topoisomerase I, partial [Klebsiella pneumoniae].	24.86	535	324	20	7	505	6	498	4e-16	92.0
rs:WP_019458040	MULTISPECIES: topoisomerase I [Acinetobacter].	23.38	539	326	18	7	505	25	516	4e-16	92.4
rs:WP_041560585	DNA topoisomerase I, partial [Nocardia farcinica].	24.79	597	338	22	7	550	19	557	4e-16	92.4
rs:WP_036659208	DNA topoisomerase I [Paenibacillus sp. FSL H8-457].	24.33	526	320	19	7	504	6	481	4e-16	92.0
rs:WP_020166935	MULTISPECIES: DNA topoisomerase I [Methylotenera].	24.77	533	322	20	7	505	5	492	4e-16	92.4
rs:WP_004203874	MULTISPECIES: DNA topoisomerase I subunit omega [Klebsiella].	24.49	535	326	19	7	505	6	498	4e-16	92.4
rs:WP_024907119	DNA topoisomerase I [Enterobacter asburiae].	24.44	540	320	20	7	505	6	498	4e-16	92.4
rs:WP_010696774	DNA topoisomerase I [Treponema denticola].	26.33	528	303	23	7	504	24	495	4e-16	92.0
rs:WP_039620968	DNA topoisomerase I [Acinetobacter harbinensis].	25.06	439	279	14	88	505	108	517	4e-16	92.4
rs:WP_001705049	DNA topoisomerase I [Escherichia coli].	25.00	544	312	23	7	505	6	498	5e-16	92.4
tr:T0ZDY5_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD42442.1};	23.45	597	342	22	7	562	6	528	5e-16	92.4
rs:WP_006343649	DNA topoisomerase I [Chlamydia psittaci].	23.77	589	357	22	7	563	6	534	5e-16	92.4
rs:WP_016966554	DNA topoisomerase I [Chlamydia psittaci].	23.52	591	356	23	7	563	6	534	5e-16	92.4
rs:WP_044785597	DNA topoisomerase I [Paenibacillus polymyxa].	23.95	526	322	19	7	504	6	481	5e-16	92.0
rs:WP_007474867	DNA topoisomerase I [Caminibacter mediatlanticus].	25.92	436	282	14	89	505	60	473	5e-16	92.0
rs:WP_021576142	DNA topoisomerase 1 [Escherichia coli].	24.63	536	324	21	7	505	6	498	5e-16	92.4
rs:WP_039420547	DNA topoisomerase I [Porphyromonas gulae].	24.05	528	304	21	7	504	5	465	5e-16	92.4
rs:WP_001437686	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	5e-16	92.4
rs:WP_006344557	DNA topoisomerase I [Chlamydophila abortus].	23.03	595	354	23	7	563	6	534	5e-16	92.4
rs:WP_008403299	DNA topoisomerase I [Bacillus isronensis].	23.67	528	321	19	7	504	6	481	5e-16	92.0
tr:D0U4M2_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.90	529	302	20	7	510	6	469	5e-16	92.4
rs:WP_016820944	DNA topoisomerase I [Paenibacillus polymyxa].	23.95	526	322	19	7	504	6	481	5e-16	92.0
sp:TOP1_STAAB	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.76	528	309	22	7	505	6	479	5e-16	92.0
rs:WP_007371932	topoisomerase I [Kosakonia radicincitans].	24.30	535	327	19	7	505	6	498	5e-16	92.4
tr:K1YG08_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.71	522	324	18	7	505	4	479	5e-16	92.0
rs:WP_044697417	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	5e-16	92.4
rs:WP_001339670	MULTISPECIES: topoisomerase I [Enterobacteriaceae].	24.35	542	318	21	7	505	6	498	5e-16	92.4
rs:WP_042242210	DNA topoisomerase I [Neochlamydia sp. S13].	23.65	592	360	22	5	564	4	535	5e-16	92.4
rs:WP_022016854	DNA topoisomerase [Bacteroides sp. CAG:545].	25.10	526	301	22	7	504	6	466	5e-16	92.0
gp:CP004054_4499	DNA topoisomerase III [Pseudomonas aeruginosa PA1]	25.00	476	291	18	99	553	28	458	5e-16	91.7
rs:WP_046157929	DNA topoisomerase I [Chromobacterium vaccinii].	25.05	543	319	20	7	510	6	499	5e-16	92.0
tr:D1KCD6_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.90	529	302	20	7	510	6	469	5e-16	92.0
rs:WP_016234290	DNA topoisomerase 1 [Escherichia coli].	24.17	542	319	21	7	505	6	498	5e-16	92.4
rs:WP_038233626	DNA topoisomerase I [Xenorhabdus szentirmaii].	25.22	460	292	16	69	505	69	499	5e-16	92.4
rs:WP_006611233	DNA topoisomerase I [Bradyrhizobium sp. ORS 285].	24.25	536	327	20	4	505	1	491	5e-16	92.4
rs:WP_009594778	DNA topoisomerase I [Paenibacillus sp. HGF5].	24.33	526	320	19	7	504	6	481	5e-16	92.0
rs:WP_045508058	DNA topoisomerase I [Kosakonia oryzae].	23.74	535	330	18	7	505	6	498	5e-16	92.4
rs:WP_015589399	DNA topoisomerase [Wolbachia endosymbiont of Drosophila simulans].	25.22	460	290	15	80	504	46	486	5e-16	92.0
rs:WP_021331401	DNA topoisomerase I [Treponema socranskii].	24.20	533	312	20	5	504	16	489	5e-16	92.0
rs:WP_042318669	DNA topoisomerase I [Citrobacter farmeri].	24.49	535	326	19	7	505	6	498	5e-16	92.4
rs:WP_001661269	DNA topoisomerase I [Escherichia coli].	25.00	544	312	23	7	505	6	498	5e-16	92.4
rs:WP_025903084	MULTISPECIES: DNA topoisomerase I [Tatumella].	25.65	460	290	17	69	505	68	498	5e-16	92.4
rs:WP_014946333	DNA topoisomerase I [Chlamydia psittaci].	23.52	591	356	23	7	563	6	534	5e-16	92.4
rs:WP_006735030	MULTISPECIES: DNA topoisomerase I [Lactobacillus].	24.57	521	321	17	7	504	11	482	5e-16	92.0
rs:WP_001354108	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	5e-16	92.4
rs:WP_032749439	DNA topoisomerase I [Klebsiella oxytoca].	24.39	537	324	19	7	505	6	498	5e-16	92.4
rs:WP_021518134	DNA topoisomerase 1 [Escherichia coli].	24.26	540	321	20	7	505	6	498	5e-16	92.4
tr:F8DPI6_LACRS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.46	436	279	14	93	504	22	435	5e-16	92.0
rs:WP_047061015	DNA topoisomerase I [Enterobacter asburiae].	24.07	540	322	19	7	505	6	498	5e-16	92.4
rs:WP_029656511	DNA topoisomerase, partial [Enterococcus faecalis].	28.05	246	165	7	307	544	78	319	5e-16	90.5
rs:WP_001714078	DNA topoisomerase I [Escherichia coli].	25.00	544	312	23	7	505	6	498	5e-16	92.4
rs:WP_025435532	DNA topoisomerase I [Eubacterium acidaminophilum].	24.13	572	337	22	7	555	6	503	5e-16	92.0
rs:WP_011900829	DNA topoisomerase [Pyrobaculum arsenaticum].	22.28	588	371	22	7	565	4	534	5e-16	91.7
rs:WP_001326307	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	5e-16	92.4
rs:WP_019192864	hypothetical protein, partial [Anaerococcus pacaensis].	25.58	301	197	10	314	604	1	284	5e-16	89.0
tr:R8QQ92_BACCE	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOP72678.1};	31.32	182	113	5	7	182	5	180	5e-16	87.8
rs:WP_001422890	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	5e-16	92.4
rs:WP_045442954	DNA topoisomerase I, partial [alpha proteobacterium MA2].	24.59	553	320	25	4	510	1	502	5e-16	92.0
rs:WP_046027573	DNA topoisomerase I [Vibrio vulnificus].	24.45	458	297	16	69	505	74	503	5e-16	92.4
rs:WP_001437935	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	5e-16	92.4
rs:WP_023955026	topoisomerase IA [Microbacterium sp. TS-1].	24.36	546	339	20	43	550	29	538	5e-16	92.4
rs:WP_032576955	DNA topoisomerase I, partial [Bacteroides fragilis].	22.79	487	313	18	43	498	2	456	5e-16	91.3
rs:WP_013571404	topoisomerase I [Vibrio vulnificus].	24.67	458	296	16	69	505	74	503	5e-16	92.4
rs:WP_041885017	DNA topoisomerase I [Pedobacter sp. NL19].	24.89	450	263	15	89	504	59	467	5e-16	92.0
rs:WP_013575912	MULTISPECIES: topoisomerase I [Rahnella].	25.00	456	298	15	69	505	68	498	5e-16	92.0
rs:WP_001335024	topoisomerase I [Escherichia coli].	24.21	541	320	21	7	505	6	498	5e-16	92.0
rs:WP_008043313	topoisomerase I [Reinekea blandensis].	23.48	541	333	18	7	505	6	507	5e-16	92.4
rs:WP_016858466	DNA topoisomerase I [Fischerella muscicola].	25.28	447	281	17	89	504	64	488	5e-16	92.0
tr:F4TDH0_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.26	540	321	20	7	505	20	512	5e-16	92.4
rs:WP_044882774	DNA topoisomerase I [Neochlamydia sp. EPS4].	23.65	592	360	22	5	564	4	535	5e-16	92.0
rs:WP_015361490	DNA topoisomerase [Nonlabens dokdonensis].	26.06	541	296	25	7	512	6	477	5e-16	92.0
rs:WP_040578076	DNA topoisomerase I, partial [Methylophilales bacterium HTCC2181].	24.41	635	371	23	7	601	5	570	5e-16	92.0
sp:TOP1_STAEQ	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.81	528	312	19	7	504	6	478	5e-16	92.0
rs:WP_033865378	DNA topoisomerase I [Escherichia coli].	24.86	535	324	21	7	505	6	498	5e-16	92.0
rs:WP_047134706	DNA topoisomerase I [bacterium JGI-5].	25.68	475	291	17	91	539	71	509	5e-16	92.0
tr:E1YHR2_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.55	550	319	22	7	516	6	499	5e-16	92.0
rs:WP_036622237	DNA topoisomerase I [Paenibacillus macerans].	25.00	532	312	22	7	505	6	483	5e-16	92.0
rs:WP_031991904	DNA topoisomerase I [Acinetobacter baumannii].	23.75	539	324	18	7	505	25	516	5e-16	92.0
tr:A0P4J6_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.41	635	371	23	7	601	5	570	5e-16	92.0
rs:WP_013218143	DNA topoisomerase I [Dehalogenimonas lykanthroporepellens].	25.40	567	303	23	7	516	8	511	5e-16	92.0
tr:Q5Z2Y2_NOCFA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.79	597	338	22	7	550	23	561	5e-16	92.4
tr:G8LDT2_ENTCL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.39	533	329	19	7	505	8	500	5e-16	92.0
rs:WP_017883608	DNA topoisomerase I [Leucobacter sp. UCD-THU].	24.08	598	343	24	7	550	8	548	5e-16	92.4
rs:WP_028052717	DNA topoisomerase I [Carboxydothermus ferrireducens].	23.99	571	339	19	7	553	5	504	5e-16	92.0
rs:WP_013370667	DNA topoisomerase I [Paenibacillus polymyxa].	23.95	526	322	19	7	504	6	481	5e-16	92.0
rs:WP_013933412	DNA topoisomerase I [Zymomonas mobilis].	24.91	534	316	21	7	505	4	487	5e-16	92.4
rs:WP_001680391	topoisomerase I [Escherichia coli].	24.16	534	329	20	7	505	6	498	5e-16	92.0
rs:WP_001454855	DNA topoisomerase I [Escherichia coli].	24.67	527	310	20	7	495	6	483	5e-16	92.0
rs:WP_021181262	DNA topoisomerase I [Serratia fonticola].	26.07	468	278	19	69	505	72	502	5e-16	92.0
rs:WP_000772478	DNA topoisomerase I [Escherichia coli].	25.67	448	264	17	91	505	58	469	5e-16	91.7
rs:WP_037543181	DNA topoisomerase I [Staphylococcus pseudintermedius].	25.00	528	311	21	7	504	6	478	5e-16	92.0
tr:Q0T5C5_SHIF8	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	542	320	20	7	505	20	512	5e-16	92.0
rs:WP_014945419	DNA topoisomerase I [Chlamydia psittaci].	23.77	589	357	22	7	563	6	534	5e-16	92.0
rs:WP_018761827	DNA topoisomerase I [Arthrobacter sp. 135MFCol5.1].	25.18	548	320	19	7	505	12	518	5e-16	92.0
rs:WP_043718443	DNA topoisomerase I [Nocardia asiatica].	24.62	593	344	22	7	550	19	557	5e-16	92.4
rs:WP_045355889	DNA topoisomerase I [Enterobacter asburiae].	24.44	540	320	20	7	505	6	498	5e-16	92.0
rs:WP_001460827	DNA topoisomerase I [Escherichia coli].	25.00	544	312	23	7	505	6	498	5e-16	92.0
rs:WP_041495996	DNA topoisomerase I [Nonlabens marinus].	25.38	599	336	27	7	568	6	530	5e-16	92.0
rs:WP_019954750	DNA topoisomerase I [Loktanella vestfoldensis].	24.49	543	327	20	4	512	1	494	5e-16	92.0
rs:WP_001353238	MULTISPECIES: topoisomerase I [Escherichia].	24.26	540	321	20	7	505	6	498	5e-16	92.0
rs:WP_032297743	DNA topoisomerase I [Escherichia coli].	25.00	544	312	23	7	505	6	498	5e-16	92.0
rs:WP_022653837	DNA topoisomerase I [Aquaspirillum serpens].	25.09	542	321	20	7	510	6	500	5e-16	92.0
rs:WP_014832223	topoisomerase I [Enterobacter cloacae].	24.44	540	320	20	7	505	6	498	5e-16	92.0
rs:WP_014229012	MULTISPECIES: topoisomerase I [Klebsiella].	24.39	537	324	19	7	505	6	498	5e-16	92.0
rs:WP_023312071	DNA topoisomerase 1 [Enterobacter cloacae].	24.44	540	320	20	7	505	6	498	5e-16	92.0
rs:WP_037925496	DNA topoisomerase I [Sulfitobacter pseudonitzschiae].	25.50	549	311	24	4	510	1	493	5e-16	92.0
rs:WP_031449654	DNA topoisomerase I [Desulfobacula sp. TS].	25.60	543	318	23	7	514	6	497	5e-16	92.0
rs:WP_005061282	DNA topoisomerase I [Acinetobacter beijerinckii].	25.62	441	274	15	88	505	108	517	5e-16	92.0
rs:WP_003471661	DNA topoisomerase I [Clostridium perfringens].	24.76	525	318	20	7	505	6	479	6e-16	92.0
rs:WP_042944939	DNA topoisomerase I [Klebsiella oxytoca].	24.02	537	326	18	7	505	6	498	6e-16	92.0
rs:WP_028098167	DNA topoisomerase I [Dongia sp. URHE0060].	26.64	548	301	23	4	505	1	493	6e-16	92.0
rs:WP_044954275	DNA topoisomerase III, partial [Faecalibacterium prausnitzii].	27.06	255	170	6	3	257	2	240	6e-16	88.6
rs:WP_046808290	DNA topoisomerase I [Serratia fonticola].	26.07	468	278	19	69	505	72	502	6e-16	92.0
rs:WP_043777938	hypothetical protein, partial [Deinococcus ficus].	23.56	505	331	17	43	515	26	507	6e-16	91.7
rs:WP_023846213	topoisomerase IA [Methanolobus tindarius].	24.86	523	326	18	43	548	47	519	6e-16	92.0
rs:WP_042237164	DNA topoisomerase I [Paenibacillus sp. FSL R5-0912].	24.95	529	313	22	7	504	6	481	6e-16	91.7
rs:WP_042642291	DNA topoisomerase I [Aeromonas eucrenophila].	22.49	538	336	16	7	505	6	501	6e-16	92.0
rs:WP_013309879	DNA topoisomerase I [Paenibacillus polymyxa].	24.24	528	318	20	7	504	6	481	6e-16	91.7
rs:WP_031837316	DNA topoisomerase III, partial [Staphylococcus aureus].	28.51	221	140	6	7	225	5	209	6e-16	87.8
rs:WP_003985132	DNA topoisomerase I [Escherichia coli].	25.14	545	310	23	7	505	6	498	6e-16	92.0
rs:WP_045620487	DNA topoisomerase I [Enterobacter cloacae].	24.44	540	320	20	7	505	6	498	6e-16	92.0
rs:WP_005239880	MULTISPECIES: topoisomerase I [Acinetobacter].	25.40	441	275	15	88	505	108	517	6e-16	92.0
rs:WP_016542433	DNA topoisomerase I [Acinetobacter gyllenbergii].	24.30	539	322	19	7	505	25	517	6e-16	92.0
rs:WP_035107542	DNA topoisomerase I, partial [Desulfovirgula thermocuniculi].	23.92	531	325	18	3	504	2	482	6e-16	91.7
rs:WP_041064802	DNA topoisomerase I [Cohnella sp. VKM B-2846].	26.65	424	267	14	107	504	77	482	6e-16	91.7
rs:WP_029399852	DNA topoisomerase 1 [Escherichia coli].	24.26	540	321	20	7	505	6	498	6e-16	92.0
rs:WP_020882439	MULTISPECIES: DNA topoisomerase I [Enterobacter cloacae complex].	24.39	533	329	19	7	505	6	498	6e-16	92.0
rs:WP_046507750	DNA topoisomerase I [Kiloniella sp. P1-1].	26.09	552	298	24	4	505	1	492	6e-16	92.0
tr:K2CW40_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.49	535	315	21	7	504	5	487	6e-16	91.7
rs:WP_004096816	DNA topoisomerase I [Acetonema longum].	23.54	633	356	24	7	593	6	556	6e-16	92.0
rs:WP_017457189	topoisomerase I [Kosakonia sacchari].	24.02	533	331	19	7	505	6	498	6e-16	92.0
rs:WP_001559015	DNA topoisomerase 1 [Escherichia coli].	24.26	540	321	20	7	505	6	498	6e-16	92.0
rs:WP_026826260	DNA topoisomerase I [Exiguobacterium marinum].	23.81	630	372	23	7	599	6	564	6e-16	91.7
rs:WP_003181746	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.48	531	322	19	112	607	82	568	6e-16	91.7
rs:WP_004692508	DNA topoisomerase I [Acinetobacter johnsonii].	26.21	435	279	15	88	505	109	518	6e-16	92.0
rs:WP_022826790	DNA topoisomerase I [Flavobacterium antarcticum].	25.84	534	284	23	7	504	6	463	6e-16	92.0
rs:WP_013681861	DNA topoisomerase I [Hippea maritima].	23.84	625	366	24	7	598	4	551	6e-16	91.7
rs:WP_011390950	DNA topoisomerase I [Rhodospirillum rubrum].	24.95	549	307	24	7	505	4	497	6e-16	92.0
rs:WP_005049701	topoisomerase I [Shigella flexneri].	23.99	542	320	20	7	505	6	498	6e-16	92.0
rs:WP_024623694	DNA topoisomerase I [Lactobacillus fabifermentans].	26.48	525	306	22	7	505	35	505	6e-16	91.7
rs:WP_019391804	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.57	521	319	20	112	599	82	561	6e-16	91.7
rs:WP_034569661	DNA topoisomerase I [Carnobacterium divergens].	24.13	543	311	21	1	504	1	481	6e-16	91.7
rs:WP_025677610	DNA topoisomerase I [Paenibacillus polymyxa].	23.95	526	322	19	7	504	6	481	6e-16	91.7
rs:WP_003863283	DNA topoisomerase I [Corynebacterium glutamicum].	25.11	474	280	18	86	505	83	535	6e-16	92.0
rs:WP_035603017	DNA topoisomerase I [Edwardsiella tarda].	25.60	461	289	20	69	505	68	498	6e-16	92.0
tr:D6J9Q0_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.26	540	321	20	7	505	8	500	6e-16	92.0
rs:WP_045855064	DNA topoisomerase I [Raoultella terrigena].	25.23	535	322	20	7	505	6	498	6e-16	92.0
rs:WP_039020811	DNA topoisomerase I [Escherichia coli].	24.26	540	321	20	7	505	6	498	6e-16	92.0
rs:WP_001309471	MULTISPECIES: DNA topoisomerase I [Escherichia].	24.26	540	321	20	7	505	6	498	6e-16	92.0
rs:WP_003449413	DNA topoisomerase I [Clostridium perfringens].	24.76	525	318	20	7	505	6	479	6e-16	91.7
rs:WP_024212192	DNA topoisomerase I [Escherichia sp. TW15838].	24.26	540	321	20	7	505	6	498	6e-16	92.0
rs:WP_041909639	MULTISPECIES: DNA topoisomerase I [Enterobacter].	24.44	540	320	20	7	505	6	498	6e-16	92.0
rs:WP_046887713	DNA topoisomerase I [Enterobacter cloacae].	24.44	540	320	20	7	505	6	498	6e-16	92.0
tr:A0A0D6NX78_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN70737.1};	26.01	542	305	27	7	505	5	493	6e-16	92.0
rs:WP_034769755	DNA topoisomerase I [Bacillus thermoamylovorans].	26.60	421	259	15	112	504	82	480	6e-16	91.7
rs:WP_035623284	DNA topoisomerase I [Flavobacterium hydatis].	25.71	529	291	25	7	504	6	463	6e-16	92.0
rs:WP_039445801	DNA topoisomerase I [Porphyromonas gulae].	24.05	528	304	21	7	504	5	465	6e-16	92.0
rs:WP_023988184	DNA topoisomerase I [Paenibacillus polymyxa].	24.24	528	318	20	7	504	6	481	6e-16	91.7
rs:WP_012905972	topoisomerase I [Citrobacter rodentium].	24.11	535	328	19	7	505	6	498	6e-16	92.0
rs:WP_037034469	DNA topoisomerase I [Rahnella sp. WP5].	25.00	456	298	15	69	505	68	498	6e-16	92.0
rs:WP_001484536	DNA topoisomerase I [Escherichia coli].	24.95	537	321	22	7	505	6	498	6e-16	92.0
rs:WP_041848588	DNA topoisomerase I [Bacillus thermoamylovorans].	26.60	421	259	15	112	504	82	480	6e-16	91.7
rs:WP_039418184	DNA topoisomerase I [Porphyromonas gulae].	23.60	534	299	20	7	504	5	465	6e-16	92.0
rs:WP_013015783	DNA topoisomerase I [Stackebrandtia nassauensis].	23.91	552	321	23	7	505	9	514	6e-16	92.0
rs:WP_028542727	DNA topoisomerase I [Paenibacillus sp. UNCCL52].	24.24	528	318	20	7	504	6	481	6e-16	91.7
rs:WP_011065946	DNA topoisomerase I [Oceanobacillus iheyensis].	26.65	424	258	14	112	505	82	482	6e-16	91.7
rs:WP_034346907	DNA topoisomerase I [Helicobacter trogontum].	26.82	440	267	17	109	512	75	495	6e-16	91.7
rs:WP_047164149	DNA topoisomerase I [Trichodesmium erythraeum].	24.47	613	355	22	5	579	3	545	6e-16	92.0
rs:WP_011896614	DNA topoisomerase I [Corynebacterium glutamicum].	25.11	474	280	18	86	505	83	535	6e-16	92.0
tr:Q0SSB8_CLOPS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.76	525	318	20	7	505	6	479	6e-16	91.7
rs:WP_029740526	DNA topoisomerase I [Enterobacter asburiae].	24.39	533	329	19	7	505	6	498	6e-16	92.0
rs:WP_021523431	DNA topoisomerase 1 [Escherichia coli].	24.21	541	320	21	7	505	6	498	6e-16	92.0
rs:WP_005091745	topoisomerase I [Shigella flexneri].	23.99	542	320	20	7	505	6	498	6e-16	92.0
rs:WP_003328956	DNA topoisomerase I [Bacillus atrophaeus].	25.90	525	306	21	112	599	82	560	6e-16	91.7
rs:WP_008474129	DNA topoisomerase I [Lactobacillus gigeriorum].	23.85	524	322	19	7	505	15	486	6e-16	91.7
tr:A0A0C7GC68_CLOSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.61	573	332	20	7	553	6	504	6e-16	91.7
rs:WP_035448310	DNA topoisomerase I [Lactobacillus animalis].	25.34	521	318	20	7	505	23	494	6e-16	91.7
rs:WP_003855832	MULTISPECIES: DNA topoisomerase I [Corynebacterium].	25.11	474	280	18	86	505	83	535	6e-16	92.0
rs:WP_001366271	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	6e-16	92.0
rs:WP_023145287	DNA topoisomerase I [Escherichia coli].	24.21	541	320	21	7	505	6	498	6e-16	92.0
rs:WP_010325857	topoisomerase I [Acinetobacter lwoffii].	26.21	435	279	15	88	505	109	518	6e-16	92.0
rs:WP_009384973	topoisomerase I [Vibrio sp. N418].	23.71	523	350	16	7	505	6	503	6e-16	92.0
rs:WP_011609954	DNA topoisomerase I [Trichodesmium erythraeum].	24.47	613	355	22	5	579	3	545	6e-16	92.0
rs:WP_024262211	DNA topoisomerase I [Escherichia coli].	24.26	540	321	20	7	505	6	498	6e-16	92.0
rs:WP_002457370	DNA topoisomerase I [Staphylococcus epidermidis].	24.67	527	314	18	7	504	6	478	6e-16	91.7
rs:WP_005291614	DNA topoisomerase I [Acinetobacter sp. NIPH 2100].	24.40	541	319	20	7	505	25	517	6e-16	92.0
rs:WP_043685774	DNA topoisomerase I [Nocardia abscessus].	24.62	593	344	22	7	550	19	557	6e-16	92.0
rs:WP_002354343	DNA topoisomerase, partial [Enterococcus faecium].	32.83	198	119	4	379	563	2	198	6e-16	89.7
rs:WP_022314822	DNA topoisomerase [Ruminococcus sp. CAG:382].	25.26	578	329	22	5	553	33	536	6e-16	91.7
rs:WP_003062355	DNA topoisomerase I [Streptococcus dysgalactiae].	23.61	521	322	16	7	504	29	496	6e-16	91.7
rs:WP_001359511	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	6e-16	92.0
rs:WP_027076999	DNA topoisomerase I [Maribacter antarcticus].	24.28	523	308	18	7	504	6	465	6e-16	92.0
rs:WP_031524090	DNA topoisomerase I, partial [Cronobacter sp. 1383].	24.21	537	325	19	7	505	6	498	6e-16	91.7
rs:WP_001252809	topoisomerase I [Escherichia coli].	24.21	541	320	21	7	505	20	512	6e-16	92.0
rs:WP_004649883	DNA topoisomerase I [Acinetobacter bohemicus].	26.14	440	273	15	88	505	108	517	6e-16	92.0
rs:WP_038040953	DNA topoisomerase I [Thermomicrobiales bacterium KI4].	25.59	547	301	24	7	504	3	492	7e-16	91.7
tr:W1PCV0_AMBTC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.42	535	313	20	27	505	366	870	7e-16	92.0
rs:WP_028068227	DNA topoisomerase I [Sphingobacterium thalpophilum].	25.34	446	269	13	89	504	59	470	7e-16	91.7
tr:D4X879_9BURK	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EFF77009.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EFF77009.1};	33.54	158	90	4	406	552	242	395	7e-16	90.9
rs:WP_005278819	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	25.40	441	275	15	88	505	108	517	7e-16	92.0
rs:WP_028821435	DNA topoisomerase I [Propionimicrobium lymphophilum].	23.34	467	291	16	86	505	72	518	7e-16	92.0
rs:WP_014470402	MULTISPECIES: DNA topoisomerase I [Bacillus subtilis group].	25.81	523	309	20	112	599	82	560	7e-16	91.7
rs:WP_040302418	DNA topoisomerase I [Aneurinibacillus aneurinilyticus].	24.71	526	317	20	7	504	6	480	7e-16	91.7
rs:WP_008295426	topoisomerase I [Congregibacter litoralis].	23.02	543	335	19	7	505	6	509	7e-16	92.0
rs:WP_041145185	DNA topoisomerase I [Raoultella ornithinolytica].	24.77	533	327	19	7	505	6	498	7e-16	92.0
rs:WP_021537199	DNA topoisomerase 1 [Escherichia coli].	24.63	536	324	21	7	505	6	498	7e-16	92.0
rs:WP_038058400	DNA topoisomerase I [Thermus sp. YIM 77409].	26.64	473	260	22	3	441	24	443	7e-16	92.0
rs:WP_020802463	DNA topoisomerase I [Klebsiella pneumoniae].	25.98	435	282	15	88	505	87	498	7e-16	92.0
rs:WP_005531228	DNA topoisomerase I [Corynebacterium striatum].	24.64	552	324	21	5	505	8	518	7e-16	92.0
tr:A0A090QNN5_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.35	542	323	21	7	505	6	503	7e-16	92.0
rs:WP_040788066	DNA topoisomerase I [Nocardia paucivorans].	23.71	599	348	20	7	550	1	545	7e-16	92.0
rs:WP_012691439	DNA topoisomerase I [Rhodococcus opacus].	25.30	589	339	22	7	550	23	555	7e-16	92.0
rs:WP_016504046	DNA topoisomerase [Candidatus Photodesmus katoptron].	23.62	436	289	14	88	504	94	504	7e-16	92.0
rs:WP_004647399	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	24.21	537	325	18	7	505	26	518	7e-16	92.0
rs:WP_012633970	DNA topoisomerase I [Anaeromyxobacter dehalogenans].	23.55	552	328	20	2	505	45	550	7e-16	91.7
rs:WP_024259893	DNA topoisomerase I [Shigella flexneri].	23.99	542	320	20	7	505	6	498	7e-16	91.7
rs:WP_044531589	DNA topoisomerase III, partial [Herbaspirillum sp. B65].	33.03	221	137	6	3	222	2	212	7e-16	87.4
rs:WP_025778061	DNA topoisomerase I [Brevibacterium sp. VCM10].	24.91	546	328	17	7	505	12	522	7e-16	92.0
rs:WP_033550377	DNA topoisomerase I [Escherichia coli].	24.63	536	324	21	7	505	6	498	7e-16	91.7
rs:WP_014824496	DNA topoisomerase I [Solibacillus silvestris].	23.67	528	321	19	7	504	6	481	7e-16	91.7
rs:WP_038988904	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	7e-16	91.7
rs:WP_004737437	topoisomerase I [Vibrio splendidus].	23.15	540	332	19	7	505	6	503	7e-16	91.7
rs:WP_022323727	DNA topoisomerase [Alistipes sp. CAG:435].	26.36	516	310	19	7	505	6	468	7e-16	91.7
rs:WP_021674657	DNA topoisomerase, partial [Peptostreptococcaceae bacterium oral taxon 113].	28.15	302	184	9	209	503	6	281	7e-16	88.6
rs:WP_046560792	DNA topoisomerase I [Kangiella geojedonensis].	24.48	531	342	18	7	505	6	509	7e-16	91.7
tr:A0A0A2RI15_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.21	541	320	21	7	505	6	498	7e-16	91.7
rs:WP_023344331	MULTISPECIES: DNA topoisomerase 1 [Enterobacter cloacae complex].	24.44	540	320	20	7	505	6	498	7e-16	91.7
rs:WP_039232450	DNA topoisomerase I [Alteromonas macleodii].	25.75	431	279	14	93	505	99	506	7e-16	91.7
rs:WP_038939790	DNA topoisomerase I [Vibrio vulnificus].	24.45	458	297	16	69	505	74	503	7e-16	91.7
rs:WP_045595170	DNA topoisomerase I [Vibrio vulnificus].	24.45	458	297	16	69	505	74	503	7e-16	91.7
rs:WP_043411100	DNA topoisomerase III, partial [Streptomyces pluripotens].	31.96	219	138	6	7	224	6	214	7e-16	87.4
rs:WP_034411083	DNA topoisomerase I [Candidatus Photodesmus katoptron].	23.62	436	289	14	88	504	94	504	7e-16	91.7
tr:U1YAP5_ANEAE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.71	526	317	20	7	504	29	503	7e-16	91.7
rs:WP_024232160	DNA topoisomerase I [Escherichia coli].	24.21	541	320	21	7	505	6	498	7e-16	91.7
rs:WP_002995012	DNA topoisomerase I [Streptococcus pyogenes].	23.61	521	322	16	7	504	29	496	7e-16	91.7
tr:U2HJ00_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.86	309	191	11	313	603	4	295	7e-16	89.4
rs:WP_020719565	hypothetical protein [Acidobacteriaceae bacterium KBS 96].	23.98	563	306	23	7	505	6	510	7e-16	91.7
gp:CP007024_751	DNA topoisomerase I [Streptococcus pyogenes STAB901]	23.95	522	319	18	7	504	29	496	7e-16	91.7
rs:WP_022901482	DNA topoisomerase I [Humibacter albus].	24.73	554	322	22	7	505	7	520	7e-16	92.0
rs:WP_001337939	DNA topoisomerase 1 [Escherichia coli].	24.21	541	320	21	7	505	6	498	7e-16	91.7
rs:WP_012311849	DNA topoisomerase I [Escherichia coli].	24.17	542	319	21	7	505	6	498	7e-16	91.7
rs:WP_036301804	DNA topoisomerase I [Methylotenera sp. L2L1].	26.18	531	317	21	7	505	5	492	7e-16	91.7
rs:WP_008911059	DNA topoisomerase I subunit omega [Providencia burhodogranariea].	26.48	438	276	17	88	505	86	497	7e-16	91.7
rs:WP_013669135	DNA topoisomerase I [Aerococcus urinae].	23.94	518	325	18	7	504	14	482	7e-16	91.7
rs:WP_015650175	DNA topoisomerase I subunit omega [Corynebacterium callunae].	25.53	474	278	19	86	505	77	529	7e-16	92.0
rs:WP_021236287	DNA topoisomerase I [Novosphingobium lindaniclasticum].	26.70	543	299	26	7	510	4	486	7e-16	91.7
tr:A0A0B8PCN3_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.57	460	294	16	69	505	74	503	7e-16	91.7
rs:WP_033646015	DNA topoisomerase I [Bacillus anthracis].	25.78	419	267	13	112	505	82	481	7e-16	91.3
rs:WP_031914761	DNA topoisomerase I [Staphylococcus aureus].	25.57	528	310	22	7	505	6	479	7e-16	91.3
rs:WP_036846973	DNA topoisomerase I [Photorhabdus temperata].	25.47	483	284	20	69	513	68	512	7e-16	91.7
rs:WP_045101789	DNA topoisomerase I [Aliivibrio wodanis].	25.22	460	291	19	69	505	74	503	7e-16	91.7
tr:A0A060VRW5_KLEPN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.98	435	282	15	88	505	89	500	7e-16	91.7
rs:WP_031935302	DNA topoisomerase I, partial [Escherichia coli].	24.68	543	315	22	7	505	6	498	7e-16	91.7
rs:WP_006583074	DNA topoisomerase I [Thermanaerovibrio velox].	25.80	531	306	22	5	505	44	516	7e-16	91.7
rs:WP_027662585	DNA topoisomerase 1 [Escherichia coli].	24.17	542	319	21	7	505	6	498	7e-16	91.7
rs:WP_004609725	DNA topoisomerase I [[Clostridium] spiroforme].	25.05	523	317	19	89	584	62	536	7e-16	91.3
rs:WP_005280639	DNA topoisomerase I [Acinetobacter sp. NIPH 3623].	25.73	443	271	16	88	505	108	517	7e-16	91.7
rs:WP_039020056	DNA topoisomerase I [Halocynthiibacter namhaensis].	24.45	544	322	21	4	510	1	492	7e-16	91.7
rs:WP_039442045	DNA topoisomerase I [Porphyromonas gulae].	23.60	534	299	20	7	504	5	465	7e-16	91.7
rs:WP_017421991	topoisomerase I [Vibrio vulnificus].	24.45	458	297	16	69	505	74	503	7e-16	91.7
rs:WP_021718458	DNA topoisomerase [Phascolarctobacterium sp. CAG:207].	25.42	602	352	24	7	580	6	538	7e-16	91.3
rs:WP_033552514	DNA topoisomerase 1 [Escherichia coli].	24.21	541	320	21	7	505	6	498	7e-16	91.7
rs:WP_015535341	DNA topoisomerase I [Faecalitalea cylindroides].	24.67	527	312	19	7	505	6	475	7e-16	91.3
rs:WP_001304419	MULTISPECIES: DNA topoisomerase I [Escherichia].	24.21	541	320	21	7	505	6	498	7e-16	91.7
rs:WP_006736530	DNA topoisomerase I [Lactobacillus iners].	24.57	521	321	17	7	504	11	482	7e-16	91.3
rs:WP_033709859	MULTISPECIES: DNA topoisomerase I, partial [Bacillus cereus group].	27.68	271	183	6	279	539	5	272	8e-16	91.3
rs:WP_020031242	hypothetical protein [gamma proteobacterium SCGC AAA168-I18].	23.69	553	328	18	7	512	6	511	8e-16	91.7
rs:WP_039446508	DNA topoisomerase I [Vibrio vulnificus].	24.45	458	297	16	69	505	74	503	8e-16	91.7
rs:WP_032342674	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	8e-16	91.7
rs:WP_047348265	DNA topoisomerase I [Enterobacter sp. GN03164].	24.02	533	331	18	7	505	6	498	8e-16	91.7
rs:WP_002485347	DNA topoisomerase I [Staphylococcus epidermidis].	24.43	528	314	18	7	504	6	478	8e-16	91.3
rs:WP_042890911	DNA topoisomerase I [Acinetobacter junii].	25.40	441	275	15	88	505	108	517	8e-16	91.7
rs:WP_005403630	topoisomerase I [Acinetobacter junii].	25.40	441	275	15	88	505	108	517	8e-16	91.7
rs:WP_004916538	DNA topoisomerase I [Acinetobacter junii].	25.40	441	275	15	88	505	108	517	8e-16	91.7
rs:WP_033901430	DNA topoisomerase I [Pseudomonas sp. FH1].	25.42	476	296	16	97	555	75	508	8e-16	91.3
rs:WP_045671983	DNA topoisomerase I [Paenibacillus beijingensis].	26.23	427	264	16	107	504	77	481	8e-16	91.3
rs:WP_034872881	DNA topoisomerase I [Endozoicomonas montiporae].	24.88	426	277	15	99	505	109	510	8e-16	91.7
rs:WP_045628896	DNA topoisomerase I [Vibrio vulnificus].	24.45	458	297	16	69	505	74	503	8e-16	91.7
rs:WP_042067134	DNA topoisomerase I, partial [Escherichia coli].	24.68	543	315	22	7	505	6	498	8e-16	91.7
rs:WP_011392540	DNA topoisomerase I [Moorella thermoacetica].	25.00	568	327	20	1	540	1	497	8e-16	91.3
rs:WP_020321645	DNA topoisomerase I [Klebsiella pneumoniae].	25.98	435	282	15	88	505	87	498	8e-16	91.7
rs:WP_012548590	DNA topoisomerase I [Dictyoglomus thermophilum].	23.64	550	330	21	1	515	1	495	8e-16	91.3
rs:XP_006844098	PREDICTED: uncharacterized protein LOC18433959 [Amborella trichopoda].	25.42	535	313	20	27	505	373	877	8e-16	92.0
tr:A5DM60_PICGU	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EDK40263.2};	24.48	580	349	24	7	547	3	532	8e-16	91.3
rs:WP_045135520	DNA topoisomerase I [Enterobacter cloacae].	24.29	531	332	18	7	505	6	498	8e-16	91.7
rs:WP_001538694	DNA topoisomerase 1 [Escherichia coli].	24.21	541	320	21	7	505	6	498	8e-16	91.7
rs:WP_033727875	DNA topoisomerase I, partial [Bacillus weihenstephanensis].	27.68	271	183	6	279	539	4	271	8e-16	91.3
rs:WP_032870742	DNA topoisomerase I [Acinetobacter baumannii].	25.73	443	271	16	88	505	108	517	8e-16	91.7
tr:T0YYR8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD40801.1}; Flags: Fragment;	33.85	192	116	8	200	384	21	208	8e-16	87.4
rs:WP_021240303	MULTISPECIES: topoisomerase I [Enterobacter].	24.44	540	320	20	7	505	6	498	8e-16	91.7
rs:WP_005087983	topoisomerase I [Shigella flexneri].	23.99	542	320	20	7	505	6	498	8e-16	91.7
rs:WP_024870611	DNA topoisomerase I [Tolumonas sp. BRL6-1].	23.48	541	328	19	7	505	6	502	8e-16	91.7
rs:WP_011054502	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	8e-16	91.3
tr:A0A061NCY7_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.05	523	325	19	93	586	56	540	8e-16	91.3
rs:WP_040105642	DNA topoisomerase I [Salinicoccus roseus].	25.18	425	270	14	107	505	77	479	8e-16	91.3
rs:WP_003955190	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	8e-16	91.7
rs:WP_003481770	DNA topoisomerase I [Clostridium perfringens].	24.95	525	317	20	7	505	6	479	8e-16	91.3
rs:WP_045908888	DNA topoisomerase I [Enterobacter cloacae].	24.44	540	320	20	7	505	6	498	8e-16	91.7
rs:WP_043000535	MULTISPECIES: DNA topoisomerase I [Citrobacter].	24.49	535	326	19	7	505	6	498	8e-16	91.7
rs:WP_032435399	DNA topoisomerase I [Klebsiella pneumoniae].	24.39	533	329	19	7	505	6	498	8e-16	91.7
rs:WP_028018800	DNA topoisomerase I [Enterobacter cloacae].	24.44	540	320	20	7	505	6	498	8e-16	91.7
rs:WP_013096367	DNA topoisomerase I [Enterobacter cloacae].	24.54	538	322	20	7	505	6	498	8e-16	91.7
rs:WP_013406929	DNA topoisomerase I [Leadbetterella byssophila].	25.48	518	308	19	7	504	6	465	8e-16	91.7
rs:WP_044257728	DNA topoisomerase I [Citrobacter sp. JT3].	24.49	535	326	19	7	505	6	498	8e-16	91.7
rs:WP_001518579	DNA topoisomerase 1 [Escherichia coli].	25.00	468	293	17	64	505	63	498	8e-16	91.7
rs:WP_023433784	DNA topoisomerase I [Lutibaculum baratangense].	25.69	545	306	23	4	504	1	490	8e-16	91.7
rs:WP_038434096	DNA topoisomerase I [Streptococcus pyogenes].	23.95	522	319	18	7	504	29	496	8e-16	91.3
rs:WP_009797455	DNA topoisomerase I [Nitrobacter sp. Nb-311A].	24.25	536	327	20	4	505	1	491	8e-16	91.7
rs:WP_032434376	DNA topoisomerase I [Klebsiella pneumoniae].	25.98	435	282	15	88	505	87	498	8e-16	91.7
rs:WP_032359226	DNA topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	8e-16	91.7
rs:WP_001421248	DNA topoisomerase I [Escherichia coli].	25.53	470	288	18	64	505	66	501	8e-16	91.7
rs:XP_009127126	PREDICTED: uncharacterized protein LOC103851997 isoform X1 [Brassica rapa].	27.05	525	293	22	47	510	390	885	8e-16	91.7
rs:WP_042037482	DNA topoisomerase I [Aeromonas popoffii].	22.41	540	334	17	7	505	6	501	8e-16	91.7
rs:WP_039266524	DNA topoisomerase I [Enterobacter sp. FB].	24.44	540	320	20	7	505	6	498	8e-16	91.7
rs:XP_009127141	PREDICTED: uncharacterized protein LOC103851997 isoform X3 [Brassica rapa].	27.05	525	293	22	47	510	389	884	8e-16	91.7
rs:XP_009127134	PREDICTED: uncharacterized protein LOC103851997 isoform X2 [Brassica rapa].	27.05	525	293	22	47	510	389	884	8e-16	91.7
rs:WP_044708788	DNA topoisomerase III, partial [Escherichia coli].	25.00	272	187	7	8	271	5	267	8e-16	88.2
rs:WP_032640977	DNA topoisomerase I [Enterobacter cloacae].	24.20	533	330	18	7	505	6	498	8e-16	91.7
rs:WP_002901763	MULTISPECIES: DNA topoisomerase I [Klebsiella].	25.98	435	282	15	88	505	87	498	8e-16	91.7
rs:WP_004958844	DNA topoisomerase I [Acinetobacter junii].	25.40	441	275	15	88	505	108	517	8e-16	91.7
rs:WP_039708255	DNA topoisomerase I, partial [marine actinobacterium MedAcidi-G1].	23.66	596	340	21	7	544	13	551	8e-16	91.3
rs:WP_018757832	DNA topoisomerase I [Paenibacillus terrigena].	24.39	533	313	21	7	504	6	483	9e-16	91.3
rs:WP_038419681	MULTISPECIES: DNA topoisomerase I [Enterobacter].	24.54	538	322	20	7	505	6	498	9e-16	91.7
rs:WP_021516023	DNA topoisomerase 1 [Escherichia coli].	24.21	541	320	21	7	505	6	498	9e-16	91.7
rs:WP_006020922	DNA topoisomerase I [Afipia broomeae].	25.23	543	308	24	7	505	4	492	9e-16	91.7
tr:D2ADR0_SHIF2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	542	320	20	7	505	20	512	9e-16	91.7
rs:WP_017222302	topoisomerase I [Moritella dasanensis].	24.68	466	286	19	70	505	72	502	9e-16	91.7
rs:WP_030127251	DNA topoisomerase I [Streptococcus pyogenes].	23.61	521	322	16	7	504	29	496	9e-16	91.3
rs:WP_036778667	DNA topoisomerase I [Pontibacillus chungwhensis].	23.76	526	326	18	7	505	6	483	9e-16	91.3
rs:WP_045168977	DNA topoisomerase I [Caldicellulosiruptor sp. Rt8.B8].	23.77	568	345	18	7	553	5	505	9e-16	91.3
rs:WP_020833479	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	9e-16	91.3
rs:WP_021759761	DNA topoisomerase I [Desulfovibrio gigas].	25.23	440	279	13	93	505	63	479	9e-16	91.3
rs:WP_029439593	DNA topoisomerase I [Bacillus thuringiensis].	26.37	421	262	16	112	505	82	481	9e-16	91.3
rs:WP_047365954	DNA topoisomerase I [Enterobacter sp. GN03191].	24.72	538	321	20	7	505	6	498	9e-16	91.7
rs:WP_029095051	DNA topoisomerase I [Budvicia aquatica].	25.73	447	288	17	79	505	78	500	9e-16	91.7
rs:WP_016328687	DNA topoisomerase I [Thermus oshimai].	25.66	456	294	16	80	505	63	503	9e-16	91.3
rs:WP_004978972	DNA topoisomerase I [Acinetobacter johnsonii].	26.21	435	279	15	88	505	109	518	9e-16	91.7
rs:WP_023853733	DNA topoisomerase I [Candidatus Pelagibacter ubique].	24.15	530	324	21	7	505	4	486	9e-16	91.7
rs:WP_001506205	DNA topoisomerase I [Escherichia coli].	24.26	540	321	20	7	505	6	498	9e-16	91.7
rs:WP_008510351	DNA topoisomerase I [Mucilaginibacter paludis].	25.39	453	257	17	7	448	6	388	9e-16	91.3
rs:WP_040443079	DNA topoisomerase I, partial [Ktedonobacter racemifer].	23.77	551	315	17	7	505	6	503	9e-16	91.3
rs:WP_037452940	DNA topoisomerase I [Skermanella stibiiresistens].	24.96	561	323	23	1	512	1	512	9e-16	91.7
rs:WP_008852824	DNA topoisomerase I [Gluconobacter morbifer].	25.00	552	313	24	7	510	5	503	9e-16	91.7
rs:WP_045620526	DNA topoisomerase I [Vibrio vulnificus].	24.67	458	296	16	69	505	74	503	9e-16	91.7
rs:WP_010355625	DNA topoisomerase I subunit omega [Escherichia sp. TW09231].	24.77	537	322	21	7	505	6	498	9e-16	91.3
rs:WP_011344688	DNA topoisomerase I [Carboxydothermus hydrogenoformans].	23.55	569	344	17	7	553	5	504	9e-16	91.3
rs:WP_021475572	DNA topoisomerase I [Pseudogulbenkiania ferrooxidans].	25.05	543	319	20	7	510	6	499	9e-16	91.3
tr:E2ZN64_9FIRM	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EFQ05379.1}; Flags: Fragment;	27.09	251	167	6	7	257	1	235	9e-16	87.8
rs:WP_038696754	DNA topoisomerase I [Paenibacillus stellifer].	25.00	528	314	23	7	504	6	481	9e-16	91.3
rs:WP_010350249	MULTISPECIES: DNA topoisomerase I subunit omega [Escherichia].	24.30	535	327	20	7	505	6	498	9e-16	91.3
rs:WP_004179471	topoisomerase I [Klebsiella pneumoniae].	25.98	435	282	15	88	505	87	498	9e-16	91.3
rs:WP_017493823	topoisomerase I [gamma proteobacterium WG36].	25.92	436	281	14	88	505	87	498	9e-16	91.3
rs:WP_022747953	DNA topoisomerase I [Lachnobacterium bovis].	23.88	536	310	21	7	504	6	481	9e-16	91.3
rs:WP_035148387	DNA topoisomerase I [Campylobacter fetus].	25.71	424	269	16	107	505	72	474	9e-16	90.9
rs:WP_031561748	DNA topoisomerase I [Ruminococcus flavefaciens].	24.24	528	320	18	7	505	5	481	9e-16	91.3
rs:WP_017689196	DNA topoisomerase I [Paenibacillus sp. PAMC 26794].	24.81	532	312	21	7	505	6	482	9e-16	91.3
tr:F3GEY9_PSESJ	SubName: Full=Orf50 {ECO:0000313|EMBL:EGH45639.1};	29.31	232	138	5	358	565	1	230	9e-16	89.4
rs:WP_044297986	DNA topoisomerase I [Psychrobacter sp. 1501(2011)].	25.60	457	282	20	84	505	88	521	9e-16	91.3
rs:WP_020588848	DNA topoisomerase I [Desulfobacter curvatus].	25.76	458	283	18	93	515	63	498	9e-16	91.3
rs:WP_020370685	MULTISPECIES: DNA topoisomerase I [Chlamydia].	24.54	599	340	26	7	563	6	534	9e-16	91.3
rs:WP_034629666	DNA topoisomerase I [Bacillus okhensis].	24.39	529	316	18	7	504	6	481	9e-16	91.3
rs:WP_010788600	DNA topoisomerase I [Bacillus atrophaeus].	25.33	525	309	21	112	599	82	560	9e-16	91.3
rs:WP_016404385	DNA topoisomerase [Clostridium sp. CAG:1013].	24.53	530	316	21	7	505	5	481	9e-16	91.3
rs:WP_003712732	toprim domain protein, partial [Lactobacillus oris].	30.77	221	135	7	5	217	3	213	9e-16	87.0
rs:WP_044634342	DNA topoisomerase I [Treponema phagedenis].	22.72	603	367	22	7	582	18	548	9e-16	91.3
tr:F5SPD8_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.60	457	282	20	84	505	85	518	9e-16	91.3
rs:WP_013846732	DNA topoisomerase I [Sphingobium chlorophenolicum].	25.05	523	316	20	7	505	4	474	9e-16	91.3
rs:WP_007202531	DNA topoisomerase I [Fictibacillus macauensis].	25.14	521	314	21	107	593	77	555	9e-16	91.3
rs:WP_033614632	DNA topoisomerase, partial [Enterococcus faecium].	27.64	246	166	6	307	544	78	319	9e-16	90.1
rs:WP_004210738	DNA topoisomerase I subunit omega [Klebsiella pneumoniae].	25.98	435	282	15	88	505	87	498	9e-16	91.3
rs:WP_014884091	topoisomerase I [Enterobacter cloacae].	24.72	538	321	20	7	505	6	498	9e-16	91.3
rs:WP_040151502	DNA topoisomerase I [Klebsiella pneumoniae].	25.98	435	282	15	88	505	87	498	9e-16	91.3
rs:WP_001484824	topoisomerase I [Escherichia coli].	24.35	542	318	21	7	505	6	498	9e-16	91.3
rs:WP_005493764	DNA topoisomerase I [Pseudoalteromonas luteoviolacea].	24.60	435	288	13	88	505	96	507	9e-16	91.3
rs:WP_010151140	DNA topoisomerase I [SAR324 cluster bacterium JCVI-SC AAA005].	25.45	554	309	23	7	512	6	503	9e-16	91.3
rs:WP_047235810	DNA topoisomerase I [Streptococcus pyogenes].	23.42	521	323	16	7	504	29	496	9e-16	91.3
rs:WP_043599342	DNA topoisomerase I [Nocardia otitidiscaviarum].	24.53	591	345	21	7	550	26	562	9e-16	91.7
rs:WP_038183221	DNA topoisomerase I [Xenorhabdus bovienii].	25.00	460	293	17	69	505	66	496	9e-16	91.3
rs:WP_003712163	toprim domain protein, partial [Lactobacillus oris].	30.77	221	135	8	5	217	3	213	9e-16	87.0
rs:WP_040832976	DNA topoisomerase I [Nocardia brevicatena].	23.80	605	340	21	7	550	19	563	9e-16	91.7
rs:WP_042029466	DNA topoisomerase 1 [Escherichia coli].	24.49	543	316	22	7	505	6	498	9e-16	91.3
rs:WP_038235709	DNA topoisomerase I [Zobellia uliginosa].	24.86	519	310	20	7	504	6	465	9e-16	91.3
tr:M4D449_BRARP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.05	525	293	22	47	510	394	889	9e-16	91.7
tr:D6TIW6_9CHLR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.14	551	313	18	7	505	6	503	9e-16	91.3
rs:WP_042308078	DNA topoisomerase I [Citrobacter werkmanii].	23.74	535	330	18	7	505	6	498	9e-16	91.3
rs:WP_037573320	DNA topoisomerase I [Staphylococcus chromogenes].	24.86	527	313	19	7	504	6	478	9e-16	91.3
rs:WP_006729968	DNA topoisomerase I [Lactobacillus iners].	24.57	521	321	17	7	504	11	482	9e-16	91.3
rs:WP_033133268	DNA topoisomerase I [Acinetobacter sp. MN12].	24.12	539	323	19	7	505	25	517	9e-16	91.3
rs:WP_035892922	DNA topoisomerase I [Kluyvera ascorbata].	24.77	537	322	21	7	505	6	498	9e-16	91.3
tr:A0A024GYV1_9MICC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.04	559	323	20	7	510	12	529	1e-15	91.3
rs:WP_002462101	topoisomerase I [Escherichia albertii].	24.35	542	318	21	7	505	6	498	1e-15	91.3
rs:WP_021458862	DNA topoisomerase I [Staphylococcus sp. EGD-HP3].	24.86	527	314	21	7	505	6	478	1e-15	90.9
rs:WP_018082189	DNA topoisomerase I [Asticcacaulis benevestitus].	24.50	547	325	21	4	510	1	499	1e-15	91.3
rs:WP_005400852	topoisomerase I [Acinetobacter johnsonii].	26.21	435	279	15	88	505	109	518	1e-15	91.3
rs:WP_040001828	DNA topoisomerase I [[Eubacterium] infirmum].	26.53	524	304	22	8	505	1	469	1e-15	90.9
rs:WP_038132716	DNA topoisomerase I [Thioclava sp. DT23-4].	26.33	490	283	23	4	469	1	436	1e-15	91.3
rs:WP_038197567	DNA topoisomerase I [Xenorhabdus bovienii].	25.00	460	293	16	69	505	66	496	1e-15	91.3
gp:CP010943_1100	DNA topoisomerase I [Staphylococcus aureus]	25.52	529	309	22	7	505	6	479	1e-15	90.9
rs:WP_046497361	DNA topoisomerase I [Syntrophomonas zehnderi].	24.63	536	317	23	1	505	1	480	1e-15	90.9
rs:WP_007674523	DNA topoisomerase I [Caulobacter sp. AP07].	24.05	553	318	25	4	510	1	497	1e-15	91.3
rs:WP_010139696	DNA topoisomerase I [Oceanicola sp. S124].	25.42	535	311	23	4	505	1	480	1e-15	91.3
rs:WP_010722281	DNA topoisomerase III, partial [Enterococcus faecium].	27.64	246	166	6	307	544	78	319	1e-15	89.7
tr:A0A0C7NLR7_9THEO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	576	333	21	5	553	4	507	1e-15	90.9
rs:WP_001560478	DNA topoisomerase 1 [Escherichia coli].	24.21	541	320	21	7	505	6	498	1e-15	91.3
tr:Q3ES69_BACTI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.30	282	192	6	279	550	8	286	1e-15	90.9
rs:WP_027954195	DNA topoisomerase I [Halobacillus kuroshimensis].	27.42	423	255	15	112	505	82	481	1e-15	90.9
rs:WP_015720878	DNA topoisomerase I [Geobacter sp. M18].	24.69	559	312	20	7	505	6	515	1e-15	91.3
rs:WP_038224847	DNA topoisomerase I [Xenorhabdus bovienii].	25.22	460	292	17	69	505	66	496	1e-15	91.3
rs:WP_036891834	hypothetical protein, partial [Prevotella corporis].	27.78	216	133	6	331	534	1	205	1e-15	88.2
rs:WP_034321765	DNA topoisomerase I [Helicobacter trogontum].	24.24	528	323	19	7	504	1	481	1e-15	91.3
tr:I7JYG3_9LACO	SubName: Full=DNA topoisomerase I-like {ECO:0000313|EMBL:CCI85520.1};	24.15	410	277	16	32	424	12	404	1e-15	90.9
rs:WP_045359707	DNA topoisomerase I [Microcystis aeruginosa].	25.32	549	317	21	5	505	3	506	1e-15	91.3
rs:WP_044111856	DNA topoisomerase I [Acinetobacter sp. MII].	24.02	537	326	18	7	505	26	518	1e-15	91.3
rs:XP_005650322	DNA topoisomerase I [Coccomyxa subellipsoidea C-169].	24.77	650	345	27	5	593	18	584	1e-15	91.3
rs:WP_033602881	DNA topoisomerase, partial [Enterococcus faecium].	28.05	246	165	7	307	544	78	319	1e-15	88.2
rs:WP_012370758	DNA topoisomerase I [Exiguobacterium sibiricum].	25.19	528	313	19	7	504	6	481	1e-15	90.9
rs:WP_045374699	DNA topoisomerase I [Enterobacter aerogenes].	24.39	537	324	19	7	505	6	498	1e-15	91.3
rs:WP_026813116	DNA topoisomerase I [Arenibacter certesii].	24.47	519	312	20	7	504	6	465	1e-15	91.3
rs:WP_005255320	DNA topoisomerase I [Acinetobacter sp. NIPH 2168].	25.73	443	271	16	88	505	108	517	1e-15	91.3
rs:WP_004957737	DNA topoisomerase I [Acinetobacter junii].	25.40	441	275	15	88	505	108	517	1e-15	91.3
rs:WP_036968862	DNA topoisomerase I [Pseudoalteromonas lipolytica].	24.77	436	286	15	88	505	96	507	1e-15	91.3
rs:WP_004802538	DNA topoisomerase I [Acinetobacter sp. CIP 56.2].	24.12	539	323	19	7	505	25	517	1e-15	91.3
rs:WP_012961160	DNA topoisomerase III [Bacillus pseudofirmus].	24.58	297	204	7	7	295	4	288	1e-15	88.2
rs:WP_022447817	DNA topoisomerase [Firmicutes bacterium CAG:460].	24.90	522	314	20	86	580	59	529	1e-15	90.9
rs:WP_045568957	DNA topoisomerase I [Vibrio sp. S234-5].	23.68	456	303	15	69	505	74	503	1e-15	91.3
tr:V7Z562_LACPN	RecName: Full=DNA topoisomerase I, plasmid {ECO:0000256|SAAS:SAAS00003555}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	25.90	525	310	22	7	505	48	519	1e-15	90.5
tr:K1RYJ4_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC48294.1}; Flags: Fragment;	32.16	199	106	7	169	364	31	203	1e-15	87.0
rs:WP_012159330	DNA topoisomerase I [Alkaliphilus oremlandii].	24.65	572	334	22	7	553	6	505	1e-15	90.9
rs:WP_035808132	DNA topoisomerase I [Jeotgalicoccus sp. 13MG44_air].	25.59	426	266	16	107	505	77	478	1e-15	90.9
rs:WP_021518705	DNA topoisomerase 1 [Escherichia coli].	23.99	542	320	21	7	505	6	498	1e-15	91.3
rs:WP_010346391	DNA topoisomerase I [Paenibacillus peoriae].	24.43	528	317	20	7	504	6	481	1e-15	90.9
rs:WP_035428063	MULTISPECIES: topoisomerase I, partial [Lactobacillus].	28.85	260	157	8	174	421	5	248	1e-15	87.4
rs:WP_010381554	topoisomerase I [Pseudoalteromonas rubra].	22.98	531	348	17	7	505	6	507	1e-15	91.3
rs:WP_025153127	DNA topoisomerase I [Morganella morganii].	24.91	538	317	19	7	505	6	495	1e-15	91.3
rs:WP_039763835	DNA topoisomerase I [Caldicellulosiruptor sp. F32].	23.55	569	344	19	7	553	5	504	1e-15	90.9
rs:WP_032292753	DNA topoisomerase I [Escherichia coli].	24.81	536	323	22	7	505	6	498	1e-15	91.3
rs:WP_046738240	DNA topoisomerase I [Acinetobacter sp. AG1].	24.12	539	323	19	7	505	25	517	1e-15	91.3
tr:G9YAG8_HAFAL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.11	446	272	17	88	505	128	539	1e-15	91.3
rs:WP_008488535	topoisomerase I [Idiomarina xiamenensis].	25.24	420	266	15	107	505	112	504	1e-15	91.3
rs:WP_033613525	DNA topoisomerase, partial [Enterococcus faecium].	28.05	246	165	7	307	544	78	319	1e-15	88.6
rs:WP_026586954	DNA topoisomerase I [Bacillus sp. NSP9.1].	26.07	422	260	15	112	504	82	480	1e-15	90.9
rs:WP_035678852	DNA topoisomerase I [Bradyrhizobium liaoningense].	24.11	535	329	19	4	505	1	491	1e-15	91.3
tr:A0A0A5LUQ5_SERMA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.58	444	268	17	88	505	87	498	1e-15	91.3
rs:WP_023316755	DNA topoisomerase 1 [Klebsiella pneumoniae].	25.98	435	282	15	88	505	87	498	1e-15	91.3
gpu:CP011144_1268	DNA topoisomerase I [Pseudoxanthomonas suwonensis]	24.28	593	345	21	7	563	6	530	1e-15	91.3
rs:WP_028181330	MULTISPECIES: DNA topoisomerase I [Bradyrhizobium].	24.11	535	329	19	4	505	1	491	1e-15	91.3
rs:WP_004637808	topoisomerase I [Acinetobacter haemolyticus].	25.40	441	275	15	88	505	108	517	1e-15	91.3
rs:WP_020000196	MULTISPECIES: DNA topoisomerase I [Desulfovibrio].	25.14	541	307	23	7	505	6	490	1e-15	90.9
rs:WP_025237092	DNA topoisomerase I [Escherichia albertii].	24.35	542	318	21	7	505	6	498	1e-15	91.3
rs:WP_036768081	DNA topoisomerase I [Photorhabdus asymbiotica].	24.67	458	297	15	69	505	68	498	1e-15	91.3
rs:WP_007430014	DNA topoisomerase I [Paenibacillus sp. Aloe-11].	24.43	528	317	20	7	504	6	481	1e-15	90.9
rs:WP_011087871	DNA topoisomerase I [Bradyrhizobium diazoefficiens].	24.21	537	326	20	4	505	1	491	1e-15	91.3
rs:WP_038415193	DNA topoisomerase I [Bacillus thuringiensis].	24.52	526	320	21	7	505	6	481	1e-15	90.9
rs:WP_034428120	DNA topoisomerase, partial [Anaerococcus pacaensis].	25.42	299	200	9	314	604	1	284	1e-15	87.8
tr:H0AA89_HALSG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.67	562	333	24	3	532	2	499	1e-15	90.9
tr:A0A078GNX0_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.05	525	293	22	47	510	396	891	1e-15	91.3
rs:WP_045596646	DNA topoisomerase I [Vibrio vulnificus].	25.00	460	292	17	69	505	74	503	1e-15	91.3
rs:WP_031929785	DNA topoisomerase, partial [Staphylococcus aureus].	28.05	246	165	7	307	544	21	262	1e-15	89.7
rs:WP_043521232	DNA topoisomerase I [Klebsiella pneumoniae].	23.83	533	332	18	7	505	6	498	1e-15	91.3
rs:WP_032647574	MULTISPECIES: DNA topoisomerase I [Enterobacter].	24.54	538	322	20	7	505	6	498	1e-15	91.3
rs:WP_013352247	DNA topoisomerase I [Bacillus amyloliquefaciens].	25.81	523	309	20	112	599	82	560	1e-15	90.9
rs:WP_045630538	DNA topoisomerase I [Enterobacter cloacae].	24.07	540	322	19	7	505	6	498	1e-15	91.3
rs:WP_010340715	DNA topoisomerase I subunit omega [Escherichia albertii].	24.35	542	318	21	7	505	6	498	1e-15	91.3
rs:WP_015834210	topoisomerase I [Photorhabdus asymbiotica].	25.33	458	294	16	69	505	68	498	1e-15	91.3
rs:WP_008942315	MULTISPECIES: topoisomerase I [Acinetobacter].	25.40	441	275	15	88	505	108	517	1e-15	91.3
rs:WP_005828774	MULTISPECIES: DNA topoisomerase III [Bacteroides].	20.92	607	414	19	4	590	1	561	1e-15	90.5
rs:WP_032460103	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	1e-15	90.9
rs:WP_033628392	DNA topoisomerase, partial [Enterococcus faecalis].	28.05	246	165	7	307	544	78	319	1e-15	88.6
rs:WP_030126679	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	1e-15	90.9
rs:WP_001614507	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	1e-15	91.3
rs:WP_001574321	DNA topoisomerase I [Escherichia coli].	24.82	544	313	22	7	505	6	498	1e-15	91.3
rs:WP_021841057	DNA topoisomerase [Veillonella sp. CAG:933].	24.84	616	358	27	5	591	61	600	1e-15	90.9
rs:WP_015254980	DNA topoisomerase I [Thermobacillus composti].	24.33	522	325	15	7	504	6	481	1e-15	90.9
rs:WP_017790186	topoisomerase I [Vibrio vulnificus].	24.45	458	297	16	69	505	74	503	1e-15	91.3
tr:A5ZUI1_9FIRM	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EDM86761.1};	26.58	301	193	11	8	289	7	298	1e-15	88.2
rs:WP_008813642	MULTISPECIES: topoisomerase I [Hafnia].	25.11	446	272	17	88	505	87	498	1e-15	91.3
rs:WP_046106690	DNA topoisomerase I [Devosia geojensis].	26.01	542	303	24	4	504	1	485	1e-15	91.3
rs:WP_018043601	DNA topoisomerase I [Methylobacterium sp. 88A].	25.23	555	314	23	4	510	1	502	1e-15	91.3
rs:WP_010332637	DNA topoisomerase I subunit omega [Escherichia albertii].	24.35	542	318	21	7	505	6	498	1e-15	91.3
rs:WP_013625429	DNA topoisomerase I [Syntrophobotulus glycolicus].	23.93	535	317	19	5	504	4	483	1e-15	90.9
rs:WP_038344890	DNA topoisomerase I [Acinetobacter sp. A47].	25.62	441	274	15	88	505	108	517	1e-15	91.3
rs:WP_000474619	hypothetical protein, partial [Streptococcus agalactiae].	24.52	416	265	15	204	607	1	379	1e-15	89.0
rs:WP_043571895	DNA topoisomerase I [Chromobacterium subtsugae].	25.14	545	316	21	7	510	6	499	1e-15	90.9
rs:WP_047243105	DNA topoisomerase I [Chromobacterium subtsugae].	25.14	545	316	21	7	510	6	499	1e-15	90.9
rs:WP_011358785	DNA topoisomerase I [Pelodictyon luteolum].	22.94	558	333	20	5	515	14	521	1e-15	90.9
rs:WP_013489103	DNA topoisomerase I [Bacillus cellulosilyticus].	23.34	527	325	20	7	505	6	481	1e-15	90.9
rs:WP_040168960	DNA topoisomerase I [Klebsiella pneumoniae].	25.98	435	282	15	88	505	87	498	1e-15	90.9
rs:WP_039565854	DNA topoisomerase I [Serratia marcescens].	26.01	446	268	17	88	505	87	498	1e-15	90.9
rs:WP_009842753	topoisomerase I [Vibrio sp. AND4].	23.48	541	330	19	7	505	6	504	1e-15	90.9
rs:WP_008915752	DNA topoisomerase I subunit omega [Providencia sneebia].	25.55	454	280	18	79	505	78	500	1e-15	90.9
rs:WP_029273334	DNA topoisomerase I [Flavobacterium sp. KJJ].	25.00	524	301	21	7	504	6	463	1e-15	90.9
rs:WP_004278474	topoisomerase I [Acinetobacter lwoffii].	24.02	537	326	18	7	505	26	518	1e-15	90.9
rs:WP_045621564	DNA topoisomerase I [Vibrio vulnificus].	25.00	460	292	17	69	505	74	503	1e-15	90.9
rs:WP_032876161	DNA topoisomerase I [Acinetobacter baumannii].	25.73	443	271	16	88	505	108	517	1e-15	90.9
tr:E6Q8V3_9ZZZZ	SubName: Full=DNA topoisomerase I, plasmid (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) {ECO:0000313|EMBL:CBI03629.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI03629.1};	24.83	451	287	16	82	505	51	476	1e-15	90.9
rs:WP_039574026	DNA topoisomerase I [Sphingopyxis sp. Kp5.2].	25.29	518	321	18	7	505	4	474	1e-15	90.9
rs:WP_044867927	DNA topoisomerase I, partial [Enterobacter cloacae].	24.30	535	327	19	7	505	6	498	1e-15	90.5
rs:WP_001362355	topoisomerase I [Escherichia coli].	24.17	542	319	21	7	505	6	498	1e-15	90.9
rs:WP_044478341	DNA topoisomerase I [Paenibacillus sp. GD11].	25.14	537	304	25	7	505	6	482	1e-15	90.9
rs:WP_031859989	DNA topoisomerase III, partial [Staphylococcus aureus].	29.95	217	139	5	333	544	1	209	1e-15	88.6
gp:CP010942_735	DNA topoisomerase I [Staphylococcus epidermidis]	24.62	528	313	18	7	504	6	478	1e-15	90.9
rs:WP_002453083	DNA topoisomerase I [Staphylococcus capitis].	25.00	524	316	19	7	504	6	478	1e-15	90.9
rs:WP_023195577	DNA topoisomerase III, partial [Salmonella enterica].	25.00	272	187	7	8	271	5	267	1e-15	87.8
rs:WP_022736269	DNA topoisomerase I [Laceyella sacchari].	26.91	431	255	17	107	504	77	480	1e-15	90.9
rs:WP_045393156	DNA topoisomerase I [Enterobacter aerogenes].	24.39	537	324	19	7	505	6	498	1e-15	90.9
rs:WP_008484103	topoisomerase I [Gallaecimonas xiamenensis].	23.76	526	327	17	7	505	6	484	1e-15	90.9
tr:A0A0B0KP49_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.73	443	271	16	88	505	108	517	1e-15	90.9
rs:WP_017746750	DNA topoisomerase I [Scytonema hofmanni].	25.00	456	271	14	97	504	72	504	1e-15	90.9
rs:WP_039928916	DNA topoisomerase I [Leptospira yanagawae].	24.95	517	315	22	76	562	14	487	1e-15	90.5
rs:WP_042870498	DNA topoisomerase I [Dickeya sp. NCPPB 569].	24.26	540	323	20	7	505	6	500	1e-15	90.9
rs:WP_039277129	DNA topoisomerase I [Paenibacillus polymyxa].	24.81	528	315	20	7	504	6	481	1e-15	90.9
tr:U2U8X5_STRPY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.95	522	319	18	7	504	29	496	1e-15	90.9
rs:WP_005083647	DNA topoisomerase I [Acinetobacter haemolyticus].	25.40	441	275	15	88	505	108	517	1e-15	90.9
rs:WP_039174320	DNA topoisomerase I [Leisingera sp. ANG-S5].	24.65	568	312	25	4	510	1	513	1e-15	90.9
rs:WP_005261741	DNA topoisomerase I [Acinetobacter sp. CIP 101966].	24.02	537	326	18	7	505	26	518	1e-15	90.9
rs:WP_026832621	DNA topoisomerase I [Exiguobacterium undae].	25.19	528	313	21	7	504	6	481	1e-15	90.9
rs:WP_004774272	DNA topoisomerase I [Acinetobacter sp. NIPH 758].	25.73	443	271	16	88	505	108	517	1e-15	90.9
rs:WP_013349813	DNA topoisomerase I [Arthrobacter arilaitensis].	25.31	557	312	25	7	505	14	524	1e-15	90.9
rs:WP_011411228	topoisomerase I [Sodalis glossinidius].	23.86	528	335	17	7	505	6	495	1e-15	90.9
rs:WP_015863435	DNA topoisomerase I [Geobacillus sp. WCH70].	26.67	420	260	12	112	504	82	480	1e-15	90.9
rs:WP_035428988	DNA topoisomerase I [Bacillus sp. UNC322MFChir4.1].	24.62	524	322	19	7	505	6	481	1e-15	90.9
rs:WP_039808911	DNA topoisomerase I [Nocardia otitidiscaviarum].	24.53	591	345	21	7	550	26	562	1e-15	90.9
rs:WP_012553896	DNA topoisomerase I [Gluconacetobacter diazotrophicus].	24.05	553	320	26	7	510	5	506	1e-15	90.9
rs:WP_016164983	DNA topoisomerase I [Acinetobacter sp. CIP 110321].	24.12	539	323	19	7	505	25	517	1e-15	90.9
rs:WP_004876697	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	26.30	441	271	16	88	505	108	517	1e-15	90.9
rs:WP_015829234	DNA topoisomerase I [Methylovorus glucosotrophus].	25.05	539	313	21	7	505	5	492	1e-15	90.9
rs:WP_019298345	MULTISPECIES: DNA topoisomerase I [Leisingera].	24.65	568	312	25	4	510	1	513	1e-15	90.9
rs:WP_017312762	DNA topoisomerase I [Fischerella sp. PCC 9339].	25.39	445	279	17	91	504	66	488	1e-15	90.9
tr:A0A075GQE8_9EURY	SubName: Full=DNA topoisomerase I (TopA) {ECO:0000313|EMBL:AIF05984.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AIF05984.1};	22.78	641	375	25	7	599	4	572	1e-15	90.9
rs:WP_046966935	DNA topoisomerase I [Luteibacter rhizovicinus].	25.91	494	293	20	109	568	79	533	1e-15	90.9
rs:WP_000513587	topoisomerase I [Salmonella enterica].	25.32	553	313	23	7	505	6	512	1e-15	90.9
rs:WP_005155136	DNA topoisomerase I [Acinetobacter sp. ANC 3929].	24.12	539	323	19	7	505	25	517	1e-15	90.9
rs:WP_013441072	DNA topoisomerase I [Methylovorus sp. MP688].	25.05	539	313	21	7	505	5	492	1e-15	90.9
rs:WP_035115298	DNA topoisomerase I [Clostridium sp. NCR].	25.33	525	314	22	7	504	6	479	1e-15	90.5
rs:WP_003341403	DNA topoisomerase I [Brevibacillus laterosporus].	24.38	525	324	19	5	504	4	480	1e-15	90.5
rs:WP_035229648	DNA topoisomerase I [Alcanivorax sp. 19-m-6].	24.40	459	299	17	69	505	79	511	1e-15	90.9
rs:WP_031548586	DNA topoisomerase I [Salinicoccus luteus].	24.94	425	271	14	107	505	77	479	1e-15	90.5
rs:WP_003622318	DNA topoisomerase I [Komagataeibacter hansenii].	24.96	557	311	26	7	510	5	507	1e-15	90.9
rs:WP_022018119	DNA topoisomerase [Firmicutes bacterium CAG:129].	23.90	544	315	22	1	505	1	484	1e-15	90.9
rs:WP_025119214	MULTISPECIES: DNA topoisomerase I [Serratia].	25.43	468	281	19	69	505	71	501	1e-15	90.9
rs:WP_005192225	DNA topoisomerase I [Acinetobacter sp. ANC 4105].	24.12	539	323	19	7	505	25	517	1e-15	90.9
rs:WP_010716652	DNA topoisomerase III, partial [Enterococcus faecalis].	28.05	246	165	7	307	544	45	286	1e-15	89.7
rs:WP_046003777	DNA topoisomerase I [Pseudoalteromonas rubra].	22.98	531	348	18	7	505	6	507	1e-15	90.9
tr:L5MMI8_9BACL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ELK39527.1};	28.63	234	149	6	3	234	2	219	1e-15	87.0
rs:WP_038966363	DNA topoisomerase I [Bradyrhizobium sp. CCBAU 41267].	24.21	537	326	20	4	505	1	491	1e-15	90.9
rs:WP_027173538	DNA topoisomerase I [Methylobacterium sp. 10].	24.96	557	313	23	4	510	1	502	1e-15	90.9
rs:WP_036381104	DNA topoisomerase I [Mogibacterium timidum].	26.82	425	258	15	105	504	71	467	1e-15	90.5
rs:WP_038501935	DNA topoisomerase I [Rhodoluna lacicola].	23.58	598	360	20	7	561	8	551	1e-15	90.9
rs:WP_040703664	DNA topoisomerase I [Nocardia takedensis].	24.11	593	347	20	7	550	19	557	1e-15	90.9
rs:WP_009514124	DNA topoisomerase I [Acinetobacter sp. WC-323].	25.73	443	271	16	88	505	108	517	1e-15	90.9
rs:WP_039189441	DNA topoisomerase I [Leisingera sp. ANG-M6].	24.65	568	312	25	4	510	1	513	1e-15	90.9
rs:WP_023364833	hypothetical protein [Spiribacter sp. UAH-SP71].	23.56	556	324	19	3	505	2	509	1e-15	90.9
rs:WP_002088184	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	25.30	419	269	14	112	505	82	481	1e-15	90.5
rs:WP_020434135	DNA topoisomerase I [Paenibacillus riograndensis].	24.24	528	318	20	7	504	6	481	1e-15	90.5
rs:WP_004850155	MULTISPECIES: topoisomerase I [Klebsiella].	24.39	537	324	19	7	505	6	498	1e-15	90.9
rs:WP_017067846	topoisomerase I [Vibrio crassostreae].	22.78	540	334	19	7	505	6	503	1e-15	90.9
rs:WP_013774011	DNA topoisomerase I [Melissococcus plutonius].	25.09	530	311	20	7	504	7	482	1e-15	90.5
rs:WP_027581240	DNA topoisomerase I [Bradyrhizobium sp. Ai1a-2].	24.07	536	328	20	4	505	1	491	1e-15	90.9
rs:WP_006447066	DNA topoisomerase I [Alicyclobacillus hesperidum].	24.44	536	307	24	7	504	6	481	1e-15	90.5
rs:WP_039027048	DNA topoisomerase I [Pseudomonas aeruginosa].	25.15	497	295	20	86	553	58	506	1e-15	90.5
rs:WP_018670812	DNA topoisomerase I [Brevibacillus laterosporus].	24.38	525	324	19	5	504	4	480	1e-15	90.5
rs:WP_026852069	hypothetical protein [Geothrix fermentans].	23.06	555	318	20	7	505	1	502	1e-15	90.9
rs:WP_038243097	DNA topoisomerase I [Xenorhabdus bovienii].	24.89	458	296	16	69	505	66	496	1e-15	90.9
rs:WP_007478962	MULTISPECIES: topoisomerase I [Acinetobacter].	26.30	441	271	16	88	505	108	517	1e-15	90.9
rs:WP_039150118	DNA topoisomerase I [Leisingera sp. ANG-DT].	24.65	568	312	25	4	510	1	513	1e-15	90.9
rs:WP_022509891	DNA topoisomerase [Clostridium sp. CAG:609].	25.05	547	328	22	80	595	50	545	1e-15	90.5
tr:F8LFA1_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.44	585	345	21	3	553	2	523	1e-15	90.9
tr:W1B3B9_KLEPN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.68	444	272	17	88	505	3	414	1e-15	90.9
rs:WP_010724793	hypothetical protein, partial [Enterococcus faecium].	28.05	246	165	7	307	544	83	324	1e-15	88.6
rs:WP_016443329	DNA topoisomerase I [Actinobaculum schaalii].	23.32	549	333	17	7	505	5	515	1e-15	90.9
rs:WP_036129296	DNA topoisomerase I [Marinobacter sp. AK21].	22.67	547	333	17	7	505	6	510	1e-15	90.9
tr:D5V7J0_ARCNC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.81	536	310	22	7	504	5	485	1e-15	90.9
rs:WP_041660203	DNA topoisomerase I [Arcobacter nitrofigilis].	24.81	536	310	22	7	504	6	486	1e-15	90.9
rs:WP_045243859	DNA topoisomerase I [Paenibacillus polymyxa].	24.33	526	320	19	7	504	6	481	1e-15	90.5
rs:WP_047258136	DNA topoisomerase I [Chromobacterium subtsugae].	24.95	545	317	21	7	510	6	499	1e-15	90.5
rs:WP_010286439	DNA topoisomerase I [Kurthia massiliensis].	27.74	429	247	17	112	504	82	483	1e-15	90.5
tr:R8ZQR5_9LEPT	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	24.95	517	315	22	76	562	13	486	1e-15	90.5
rs:WP_005210345	DNA topoisomerase I [Acinetobacter sp. NIPH 1867].	24.12	539	323	19	7	505	25	517	1e-15	90.9
rs:WP_004659079	DNA topoisomerase I [Acinetobacter sp. NIPH 236].	24.12	539	323	19	7	505	25	517	1e-15	90.9
rs:WP_025718462	DNA topoisomerase I [Paenibacillus sp. 1-18].	23.95	526	322	19	7	504	6	481	1e-15	90.5
tr:A0A0D6A3Q4_9LACO	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:BAQ57309.1};	23.65	520	328	17	7	505	17	488	1e-15	90.5
rs:WP_022011721	DNA topoisomerase III [Bacteroides fragilis CAG:558].	30.99	213	132	5	330	531	3	211	1e-15	89.0
rs:WP_042048623	DNA topoisomerase I [Aeromonas simiae].	22.76	536	337	17	7	505	6	501	1e-15	90.9
rs:WP_039111492	DNA topoisomerase I [Flavobacterium sp. KMS].	25.71	529	291	25	7	504	6	463	1e-15	90.9
rs:WP_002984618	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	1e-15	90.5
rs:WP_005323095	DNA topoisomerase I [Corynebacterium pseudogenitalium].	24.90	526	304	24	40	505	30	524	1e-15	90.9
rs:WP_014259387	DNA topoisomerase I [Desulfovibrio africanus].	24.54	538	316	19	7	505	6	492	1e-15	90.5
tr:A0A0D8HLN7_9ACTN	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:KJF18900.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJF18900.1};	24.23	582	317	18	7	510	6	541	1e-15	90.9
rs:WP_036642054	DNA topoisomerase I [Paenibacillus sp. FSL R5-808].	24.20	529	317	20	7	504	6	481	1e-15	90.5
rs:WP_004718025	DNA topoisomerase I [Acinetobacter guillouiae].	25.85	472	278	19	56	505	97	518	1e-15	90.9
rs:WP_011284793	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	1e-15	90.5
rs:WP_045400177	DNA topoisomerase I [Enterobacter asburiae].	24.63	540	319	20	7	505	6	498	1e-15	90.9
rs:WP_005285326	topoisomerase I [Edwardsiella tarda].	25.38	461	290	20	69	505	68	498	1e-15	90.9
rs:WP_041772386	DNA topoisomerase [Leptospirillum ferriphilum].	23.88	557	318	24	5	512	10	509	1e-15	90.5
tr:C2PZI4_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.30	419	269	14	112	505	52	451	1e-15	90.5
rs:WP_038413679	DNA topoisomerase I [Bacillus thuringiensis].	25.65	421	265	16	112	505	82	481	1e-15	90.5
rs:WP_005117044	topoisomerase I [Shigella flexneri].	24.35	542	318	21	7	505	6	498	1e-15	90.9
rs:WP_029057500	DNA topoisomerase I [Stappia stellulata].	24.96	557	317	24	4	512	1	504	1e-15	90.9
rs:WP_034611665	DNA topoisomerase I [Acinetobacter sp. ETR1].	25.85	472	278	19	56	505	97	518	1e-15	90.9
tr:V5RV70_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.72	538	316	20	7	510	4	486	1e-15	90.5
rs:WP_004656000	DNA topoisomerase I [Acinetobacter sp. NIPH 809].	24.12	539	323	19	7	505	25	517	2e-15	90.9
rs:WP_042529016	DNA topoisomerase I [Corynebacterium singulare].	24.40	545	326	22	5	505	10	512	2e-15	90.9
rs:WP_015639701	DNA topoisomerase, partial [Lactobacillus plantarum].	28.85	260	157	8	174	421	14	257	2e-15	87.0
rs:WP_043282143	hypothetical protein, partial [Pseudonocardia sp. P2].	23.33	553	331	21	7	505	23	536	2e-15	90.9
rs:WP_029343511	DNA topoisomerase I [Lactococcus garvieae].	25.76	524	307	22	7	504	35	502	2e-15	90.5
rs:WP_003336897	DNA topoisomerase I [Brevibacillus laterosporus].	24.38	525	324	19	5	504	4	480	2e-15	90.5
rs:WP_039066768	DNA topoisomerase I [Staphylococcus xylosus].	25.76	524	311	19	7	504	6	477	2e-15	90.5
rs:WP_046789963	DNA topoisomerase I [Salinicoccus halodurans].	25.24	420	276	13	107	505	77	479	2e-15	90.5
rs:WP_038141185	DNA topoisomerase I [Thiothrix lacustris].	25.93	536	311	22	7	505	6	492	2e-15	90.5
rs:WP_041409019	DNA topoisomerase I [Shewanella sp. MR-4].	23.99	542	329	19	7	505	6	507	2e-15	90.9
rs:WP_015810713	DNA topoisomerase I [Dyadobacter fermentans].	24.86	531	297	21	7	505	6	466	2e-15	90.5
rs:WP_039424352	DNA topoisomerase I, partial [Porphyromonas gulae].	29.86	221	125	8	172	389	2	195	2e-15	86.3
rs:WP_004620068	DNA topoisomerase I [Caulobacter vibrioides].	24.68	547	322	24	4	510	1	497	2e-15	90.9
rs:WP_023275865	DNA topoisomerase I [Mucispirillum schaedleri].	23.82	529	327	21	7	505	8	490	2e-15	90.5
rs:WP_036353378	DNA topoisomerase I [Microvirga sp. BSC39].	24.19	558	316	23	4	510	1	502	2e-15	90.9
tr:X8IR60_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.82	425	258	15	105	504	98	494	2e-15	90.5
rs:WP_047005924	DNA topoisomerase I [Erythrobacter gangjinensis].	24.86	535	321	19	7	510	4	488	2e-15	90.5
rs:WP_008491745	DNA topoisomerase I [SAR86 cluster bacterium SAR86E].	24.41	553	335	20	3	512	2	514	2e-15	90.5
rs:WP_024753357	DNA topoisomerase I [Treponema phagedenis].	22.72	603	367	22	7	582	18	548	2e-15	90.5
gp:CP000446_1580	DNA topoisomerase I [Shewanella sp. MR-4]	23.99	542	329	19	7	505	22	523	2e-15	90.9
tr:A0A0B8QHJ9_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.18	459	295	16	69	504	74	502	2e-15	89.7
rs:WP_020214756	DNA topoisomerase I [Flavobacterium rivuli].	25.00	528	298	23	7	505	6	464	2e-15	90.5
rs:WP_047060003	DNA topoisomerase I [Edwardsiella tarda].	25.38	461	290	20	69	505	68	498	2e-15	90.5
rs:WP_021380353	DNA topoisomerase I [Peptoclostridium difficile].	26.60	530	305	24	5	504	4	479	2e-15	90.5
rs:XP_007158787	hypothetical protein PHAVU_002G181900g [Phaseolus vulgaris].	25.10	522	310	19	47	510	266	764	2e-15	90.9
tr:A0A059XXD1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.24	555	324	22	5	512	54	553	2e-15	90.5
tr:I0TDW9_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EID33822.1};	26.77	269	169	10	295	550	2	255	2e-15	87.4
rs:WP_011150808	topoisomerase I [Vibrio vulnificus].	24.78	460	293	17	69	505	74	503	2e-15	90.5
rs:WP_022085983	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:197].	25.70	498	293	22	47	504	21	481	2e-15	90.5
rs:WP_004818820	DNA topoisomerase I [Acinetobacter guillouiae].	25.85	472	278	19	56	505	97	518	2e-15	90.5
rs:WP_020037415	hypothetical protein [gamma proteobacterium SCGC AAA168-P09].	23.51	553	329	18	7	512	6	511	2e-15	90.5
rs:WP_011541512	DNA topoisomerase I [Sphingopyxis alaskensis].	24.86	519	322	18	7	505	4	474	2e-15	90.5
rs:WP_033897283	DNA topoisomerase I [Pseudomonas sp. FH1].	24.48	531	328	19	41	539	3	492	2e-15	90.1
rs:WP_020814402	DNA topoisomerase I [[Clostridium] papyrosolvens].	24.49	539	311	22	7	504	6	489	2e-15	90.5
rs:WP_041035352	DNA topoisomerase I [Serratia marcescens].	26.01	446	268	17	88	505	87	498	2e-15	90.5
rs:WP_015938306	DNA topoisomerase I [Arthrobacter chlorophenolicus].	24.82	548	326	18	7	505	12	522	2e-15	90.5
tr:F2NLP3_MARHT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.21	537	325	23	1	505	1	487	2e-15	90.5
rs:WP_009469347	DNA topoisomerase I [Roseibium sp. TrichSKD4].	25.31	565	312	25	4	512	1	511	2e-15	90.5
rs:WP_027338680	DNA topoisomerase I [Halonatronum saccharophilum].	25.86	526	310	21	7	505	13	485	2e-15	90.5
rs:WP_020195007	topoisomerase I [Vibrio owensii].	23.19	539	334	18	7	505	6	504	2e-15	90.5
rs:WP_005250631	DNA topoisomerase I [Acinetobacter sp. CIP 102136].	24.02	537	326	18	7	505	26	518	2e-15	90.5
rs:WP_021429755	DNA topoisomerase I [[Clostridium] bifermentans].	25.33	525	314	22	7	504	6	479	2e-15	90.5
rs:WP_029507317	DNA topoisomerase I [Lactobacillus animalis].	25.48	518	315	20	10	505	2	470	2e-15	90.1
rs:WP_019910391	DNA topoisomerase I [Paenibacillus sp. HW567].	25.76	427	266	16	107	504	77	481	2e-15	90.5
rs:WP_008329900	DNA topoisomerase I [Maritimibacter alkaliphilus].	24.91	550	317	23	4	510	1	497	2e-15	90.5
rs:WP_005218427	DNA topoisomerase I [Acinetobacter sp. ANC 3862].	24.12	539	323	19	7	505	25	517	2e-15	90.5
rs:WP_016646110	DNA topoisomerase I [Campylobacter ureolyticus].	23.89	519	325	17	7	505	5	473	2e-15	90.1
tr:A0A0C6FVI5_STRPY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.75	522	320	18	7	504	29	496	2e-15	90.5
rs:WP_047235284	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	2e-15	90.5
rs:WP_016235984	DNA topoisomerase 1 [Escherichia coli].	24.17	542	319	21	7	505	6	498	2e-15	90.5
tr:W1D4K4_ECOLX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.68	444	272	17	88	505	3	414	2e-15	90.5
rs:WP_039841572	DNA topoisomerase I [Vibrio owensii].	23.19	539	334	18	7	505	6	504	2e-15	90.5
rs:WP_036152236	DNA topoisomerase I [Lysinibacillus odysseyi].	25.58	430	263	15	107	504	77	481	2e-15	90.1
rs:WP_030125930	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	2e-15	90.5
rs:WP_005162646	DNA topoisomerase I [Acinetobacter sp. NIPH 284].	24.12	539	323	19	7	505	25	517	2e-15	90.5
rs:WP_008122907	DNA topoisomerase I [Phyllobacterium sp. YR531].	25.71	560	306	28	4	510	1	503	2e-15	90.5
rs:WP_039118730	DNA topoisomerase I [Flavobacterium sp. JRM].	25.81	527	293	25	7	504	6	463	2e-15	90.5
rs:WP_042751142	topoisomerase I, partial [Lactobacillus brevis].	27.16	313	199	11	306	603	10	308	2e-15	89.0
rs:WP_002989768	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	2e-15	90.5
rs:WP_029406632	DNA topoisomerase I [Thiomicrospira sp. Milos-T2].	24.71	514	317	20	7	504	5	464	2e-15	90.5
rs:WP_012222293	DNA topoisomerase I [Gluconacetobacter diazotrophicus].	24.05	553	320	26	7	510	5	506	2e-15	90.5
rs:WP_006280185	MULTISPECIES: DNA topoisomerase I [Wolbachia].	24.39	533	318	19	7	504	4	486	2e-15	90.5
rs:WP_041658130	DNA topoisomerase I, partial [Marinithermus hydrothermalis].	24.21	537	325	23	1	505	1	487	2e-15	90.5
rs:WP_044121391	DNA topoisomerase I, partial [Anaerobiospirillum succiniciproducens].	25.06	443	275	16	88	505	84	494	2e-15	90.5
rs:WP_040075361	DNA topoisomerase I [Enterobacteriaceae bacterium ATCC 29904].	24.39	537	324	22	7	505	6	498	2e-15	90.5
rs:WP_038896310	DNA topoisomerase I [Vibrio owensii].	23.19	539	334	18	7	505	6	504	2e-15	90.5
rs:WP_035983940	DNA topoisomerase I [Leptospira meyeri].	24.31	473	288	18	81	510	29	474	2e-15	90.1
rs:WP_023655168	DNA topoisomerase I [Erwinia piriflorinigrans].	25.27	459	293	16	69	505	43	473	2e-15	90.5
rs:WP_046519309	DNA topoisomerase I [Rheinheimera sp. IITR-13].	23.30	528	338	16	7	505	6	495	2e-15	90.5
rs:WP_001286959	DNA topoisomerase I [Bacillus thuringiensis].	25.54	419	268	14	112	505	82	481	2e-15	90.1
rs:WP_018883417	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	25.09	530	311	21	7	504	6	481	2e-15	90.1
rs:WP_047002751	DNA topoisomerase I [Erythrobacter sp. KA37].	23.75	539	322	21	7	510	4	488	2e-15	90.5
rs:WP_046464367	DNA topoisomerase I [Staphylococcus warneri].	25.43	527	310	20	7	504	6	478	2e-15	90.1
rs:WP_019349908	DNA topoisomerase I [Fluoribacter dumoffii].	25.23	535	318	16	7	505	6	494	2e-15	90.5
rs:WP_029376441	DNA topoisomerase 1 [Staphylococcus epidermidis].	24.62	528	313	19	7	504	6	478	2e-15	90.1
rs:WP_017638385	DNA topoisomerase I [Staphylococcus sp. E463].	25.05	527	312	20	7	504	6	478	2e-15	90.1
rs:WP_025017587	DNA topoisomerase III [Bacteroides sartorii].	21.90	612	402	24	4	590	1	561	2e-15	90.1
rs:WP_017445700	hypothetical protein [Gayadomonas joobiniege].	24.21	541	326	20	7	505	6	504	2e-15	90.5
tr:T1D6H2_9ZZZZ	SubName: Full=DNA topoisomerase III beta {ECO:0000313|EMBL:EQD77880.1}; Flags: Fragment;	29.43	282	157	10	75	335	27	287	2e-15	87.8
rs:WP_044166537	DNA topoisomerase III, partial [Staphylococcus aureus].	30.85	188	123	5	377	559	9	194	2e-15	88.2
rs:WP_040520241	DNA topoisomerase I, partial [Glaciecola punicea].	25.69	432	282	14	93	505	99	510	2e-15	90.5
rs:WP_036965781	DNA topoisomerase I [Providencia alcalifaciens].	27.09	443	267	18	88	505	95	506	2e-15	90.5
rs:WP_038033385	MULTISPECIES: DNA topoisomerase I [Thermotoga].	25.27	554	319	21	7	544	9	483	2e-15	90.1
rs:WP_028321406	DNA topoisomerase I [Desulfatiglans anilini].	25.23	539	308	20	7	505	6	489	2e-15	90.5
rs:WP_045730466	DNA topoisomerase I [Arthrobacter chlorophenolicus].	24.95	549	324	18	7	505	12	522	2e-15	90.5
rs:WP_042214914	DNA topoisomerase I [Paenibacillus borealis].	24.53	530	314	23	7	504	6	481	2e-15	90.1
tr:C2N519_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.65	421	265	16	112	505	52	451	2e-15	90.1
rs:WP_009851878	DNA topoisomerase I [beta proteobacterium KB13].	23.88	536	323	17	7	504	5	493	2e-15	90.5
rs:WP_005441649	topoisomerase I [Vibrio harveyi].	23.19	539	334	18	7	505	6	504	2e-15	90.5
rs:WP_003475272	DNA topoisomerase I [Clostridium perfringens].	24.76	525	318	20	7	505	6	479	2e-15	90.1
rs:WP_039609901	DNA topoisomerase I [Pseudoalteromonas luteoviolacea].	22.84	543	334	16	7	505	6	507	2e-15	90.5
rs:WP_028954508	DNA topoisomerase I [Synechocystis sp. PCC 7509].	25.16	457	271	18	103	516	78	506	2e-15	90.1
rs:WP_043084341	DNA topoisomerase I [Pluralibacter gergoviae].	24.49	539	321	21	7	505	6	498	2e-15	90.5
rs:WP_021570479	DNA topoisomerase 1 [Escherichia coli].	24.17	542	319	21	7	505	6	498	2e-15	90.5
rs:WP_038819903	DNA topoisomerase I [Pseudomonas aeruginosa].	24.55	497	298	19	86	553	58	506	2e-15	90.1
tr:T0DM55_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.19	613	374	21	7	582	77	623	2e-15	90.5
rs:WP_034291938	DNA topoisomerase I [Alysiella crassa].	26.06	518	302	21	103	581	73	548	2e-15	90.5
rs:WP_009707099	topoisomerase I [Vibrio sp. HENC-03].	23.19	539	334	18	7	505	6	504	2e-15	90.5
rs:WP_002765685	DNA topoisomerase I [Microcystis aeruginosa].	24.59	549	321	19	5	505	3	506	2e-15	90.5
rs:XP_001483632	hypothetical protein PGUG_04361 [Meyerozyma guilliermondii ATCC 6260].	24.48	580	349	23	7	547	3	532	2e-15	90.1
rs:WP_031413665	DNA topoisomerase I [Brevibacillus laterosporus].	24.38	525	324	19	5	504	4	480	2e-15	90.1
rs:WP_028089487	DNA topoisomerase I [Dolichospermum circinale].	25.77	454	281	13	89	505	72	506	2e-15	90.5
rs:WP_007680956	DNA topoisomerase I [Novosphingobium sp. AP12].	26.01	546	300	24	7	510	4	487	2e-15	90.5
tr:A5AWM5_VITVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.87	518	295	23	47	505	411	898	2e-15	90.5
tr:K8AML0_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.45	533	334	18	7	505	20	512	2e-15	90.5
rs:WP_025104275	DNA topoisomerase I [Microbacterium paraoxydans].	23.18	548	329	19	7	505	8	512	2e-15	90.5
gpu:CP007601_554	DNA topoisomerase 1 [Staphylococcus capitis subsp. capitis]	24.86	531	308	19	7	504	6	478	2e-15	90.1
rs:WP_033672103	DNA topoisomerase I [Bacillus gaemokensis].	26.30	422	261	13	112	505	82	481	2e-15	90.1
rs:WP_034915106	DNA topoisomerase I [Erwinia sp. 9145].	26.15	436	259	17	99	505	97	498	2e-15	90.5
rs:WP_039247669	DNA topoisomerase I [Brevundimonas nasdae].	24.73	562	301	25	7	510	4	501	2e-15	90.5
tr:K0FR22_BACTU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.54	419	268	14	112	505	52	451	2e-15	90.1
rs:WP_005051290	DNA topoisomerase I [Acinetobacter beijerinckii].	25.40	441	275	15	88	505	108	517	2e-15	90.5
rs:WP_022013312	DNA topoisomerase [Clostridium sp. CAG:122].	24.95	537	302	24	7	504	6	480	2e-15	90.1
tr:F9MPK6_9FIRM	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EGS33035.1};	28.70	230	147	6	8	233	5	221	2e-15	87.4
rs:WP_036217009	DNA topoisomerase I [Marinospirillum minutulum].	22.93	532	340	17	7	505	6	500	2e-15	90.5
rs:WP_010364821	topoisomerase I [Pseudoalteromonas citrea].	22.55	541	336	17	7	504	6	506	2e-15	90.5
rs:WP_029516985	DNA topoisomerase I [Paenibacillus polymyxa].	24.05	528	319	20	7	504	6	481	2e-15	90.1
rs:WP_040195133	DNA topoisomerase I [Clostridium sp. CL-6].	24.58	541	299	24	7	504	6	480	2e-15	90.1
rs:NP_194849	DNA topoisomerase, type IA, core [Arabidopsis thaliana].	26.08	625	345	27	36	607	481	1041	2e-15	90.5
rs:WP_033792958	hypothetical protein, partial [Helicobacter pylori].	25.33	529	344	22	34	543	24	520	2e-15	90.1
rs:WP_040352784	DNA topoisomerase I, partial [Blastopirellula marina].	26.33	547	312	23	7	505	3	506	2e-15	90.5
rs:WP_038908015	DNA topoisomerase I [Dickeya zeae].	26.20	439	276	17	88	505	95	506	2e-15	90.5
rs:WP_019820987	topoisomerase I [Vibrio splendidus].	22.78	540	334	19	7	505	6	503	2e-15	90.5
rs:WP_001286964	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	25.65	421	265	16	112	505	82	481	2e-15	90.1
rs:WP_005107951	DNA topoisomerase I [Acinetobacter lwoffii].	24.02	537	326	18	7	505	26	518	2e-15	90.5
rs:WP_022493747	DNA topoisomerase [Clostridium sp. CAG:628].	24.20	533	307	20	7	506	5	473	2e-15	90.1
tr:X1EDM6_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_C01304 {ECO:0000313|EMBL:GAH30712.1}; Flags: Fragment;	22.22	486	335	13	7	478	4	460	2e-15	89.4
rs:WP_036806692	DNA topoisomerase I [Planomicrobium glaciei].	25.85	530	305	23	7	504	6	479	2e-15	90.1
rs:WP_031811378	DNA topoisomerase III, partial [Staphylococcus aureus].	28.18	220	140	6	7	224	5	208	2e-15	85.9
tr:A3ZX95_9PLAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.33	547	312	23	7	505	13	516	2e-15	90.5
tr:A0A0D0FB34_LACBR	SubName: Full=Lactobacillus brevis strain TMW 1.313 Scaffold_5_TMW1313, whole genome shotgun sequence {ECO:0000313|EMBL:KIO93453.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIO93453.1};	27.16	313	199	11	306	603	4	302	2e-15	88.6
rs:WP_011006940	DNA topoisomerase I [Chlamydophila caviae].	23.18	591	358	23	7	563	6	534	2e-15	90.1
rs:WP_014108707	topoisomerase I [Glaciecola nitratireducens].	24.21	541	328	21	7	505	6	506	2e-15	90.5
rs:WP_040991531	MULTISPECIES: DNA topoisomerase I [Vibrio].	23.33	540	331	18	7	505	6	503	2e-15	90.5
tr:D4LJ45_9FIRM	SubName: Full=Draft genome {ECO:0000313|EMBL:CBL19856.1};	27.91	301	189	12	8	289	7	298	2e-15	87.8
tr:A0A077KUW3_ACIGI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.85	472	278	19	56	505	97	518	2e-15	90.5
rs:WP_028792557	DNA topoisomerase I [Thalassobaculum salexigens].	25.41	543	310	23	7	505	5	496	2e-15	90.5
rs:WP_016768417	topoisomerase I [Vibrio cyclitrophicus].	22.78	540	334	19	7	505	6	503	2e-15	90.1
tr:F6H2W0_VITVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.78	516	296	22	47	504	112	598	2e-15	90.5
rs:WP_010719464	MULTISPECIES: DNA topoisomerase I [Enterococcus].	23.71	523	326	18	7	504	7	481	2e-15	90.1
rs:WP_011155021	DNA topoisomerase I [Ehrlichia ruminantium].	25.69	541	325	20	4	510	1	498	2e-15	90.1
rs:NP_269314	putative DNA topoisomerase I [Streptococcus pyogenes M1 GAS].	23.75	522	320	18	7	504	29	496	2e-15	90.1
rs:WP_026348843	DNA topoisomerase I [Psychrobacter lutiphocae].	24.07	536	330	23	7	505	26	521	2e-15	90.1
rs:WP_020028714	hypothetical protein [gamma proteobacterium SCGC AAA076-F14].	26.00	527	305	22	7	510	6	470	2e-15	90.1
rs:WP_022060820	DNA topoisomerase [Corallococcus sp. CAG:1435].	23.10	606	364	20	7	579	4	540	2e-15	90.1
rs:WP_037457389	DNA topoisomerase I [Sphingobium chlorophenolicum].	25.05	523	316	20	7	505	4	474	2e-15	90.1
rs:WP_012884779	topoisomerase I [Dickeya dadantii].	27.04	429	264	18	99	505	105	506	2e-15	90.1
rs:WP_026721293	DNA topoisomerase I [Fischerella sp. PCC 9431].	25.05	519	298	15	89	566	72	540	2e-15	90.1
rs:WP_026820750	DNA topoisomerase I [Arthrobacter castelli].	26.04	434	276	17	7	425	5	408	2e-15	90.1
rs:WP_040917580	DNA topoisomerase I [Leptospira meyeri].	24.47	474	286	19	81	510	29	474	2e-15	89.7
rs:XP_007225278	hypothetical protein PRUPE_ppa001428mg [Prunus persica].	26.89	528	300	23	36	505	28	527	2e-15	90.1
rs:WP_023605114	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	2e-15	90.1
tr:H5T9E7_9ALTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.69	432	282	14	93	505	99	510	2e-15	90.1
rs:WP_026590316	DNA topoisomerase I [Bacillus sp. UNC437CL72CviS29].	24.29	527	320	17	7	505	6	481	2e-15	90.1
gp:CP002608_247	DNA topoisomerase [Chlamydophila pecorum E58]	25.67	596	336	24	7	563	13	540	2e-15	90.1
rs:WP_014407586	DNA topoisomerase I [Streptococcus pyogenes].	23.42	521	323	17	7	504	29	496	2e-15	90.1
rs:WP_021757590	DNA topoisomerase [Chlamydia pecorum].	25.67	596	336	24	7	563	6	533	2e-15	90.1
rs:WP_011255493	DNA topoisomerase I [Ehrlichia ruminantium].	25.69	541	325	20	4	510	1	498	2e-15	90.1
rs:WP_039274721	DNA topoisomerase I [Paenibacillus polymyxa].	24.05	528	319	20	7	504	6	481	2e-15	90.1
rs:WP_006712555	topoisomerase I [Vibrio ichthyoenteri].	23.71	523	350	16	7	505	6	503	2e-15	90.1
rs:WP_025706262	DNA topoisomerase I [Paenibacillus graminis].	24.24	528	318	21	7	504	6	481	2e-15	90.1
tr:Q2B124_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EAR63545.1};	29.58	240	136	10	321	550	1	217	2e-15	87.8
rs:WP_040243794	DNA topoisomerase I [Klebsiella pneumoniae].	24.39	533	329	19	7	505	6	498	2e-15	90.1
rs:WP_037258583	DNA topoisomerase I [Roseivivax halodurans].	25.00	496	291	20	4	471	1	443	2e-15	90.1
rs:WP_015140537	DNA topoisomerase I [Nostoc sp. PCC 7524].	23.87	444	289	14	91	505	66	489	2e-15	90.1
rs:WP_001695925	DNA topoisomerase I [Escherichia coli].	24.17	542	319	21	7	505	6	498	2e-15	90.1
tr:A0A097ART4_THEKI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.04	570	340	20	7	553	6	505	2e-15	90.1
rs:WP_013040040	DNA topoisomerase I [Sphingobium japonicum].	24.77	537	312	20	7	505	4	486	2e-15	90.1
rs:WP_011916787	DNA topoisomerase I [Caldicellulosiruptor saccharolyticus].	23.68	570	342	20	7	553	5	504	2e-15	90.1
rs:WP_015333594	DNA topoisomerase I [Fibrella aestuarina].	25.23	539	293	20	7	505	6	474	2e-15	90.1
rs:WP_042217744	DNA topoisomerase I [Lactococcus garvieae].	25.71	529	301	22	7	504	35	502	2e-15	90.1
rs:WP_017261889	DNA topoisomerase I [Lactobacillus rossiae].	23.71	523	322	20	7	504	19	489	2e-15	90.1
rs:WP_013581109	DNA topoisomerase [Granulicella tundricola].	23.77	568	326	21	3	510	2	522	2e-15	90.1
rs:WP_007685816	DNA topoisomerase I [Sphingobium indicum].	24.77	537	312	20	7	505	4	486	2e-15	90.1
rs:WP_031755974	DNA topoisomerase I [Pseudomonas aeruginosa].	24.95	497	296	21	86	553	58	506	2e-15	89.7
rs:WP_010652788	DNA topoisomerase I [Fluoribacter dumoffii].	25.23	535	318	16	7	505	6	494	2e-15	90.1
rs:XP_002280960	PREDICTED: uncharacterized protein LOC100247441 [Vitis vinifera].	25.73	517	297	22	47	505	398	885	2e-15	90.5
rs:WP_038433403	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	2e-15	89.7
rs:WP_005856589	DNA topoisomerase I [Sagittula stellata].	24.53	587	337	24	4	549	1	522	2e-15	90.1
rs:WP_040314066	hypothetical protein, partial [Bacteriovorax sp. BAL6_X].	22.19	613	374	21	7	582	82	628	2e-15	90.1
rs:WP_015378045	MULTISPECIES: DNA topoisomerase I, omega subunit [Serratia].	26.01	446	268	17	88	505	87	498	2e-15	90.1
rs:WP_001487192	DNA topoisomerase I [Escherichia coli].	24.17	542	319	21	7	505	6	498	2e-15	90.1
rs:WP_005315206	DNA topoisomerase I [Acinetobacter sp. ANC 3880].	24.12	539	323	19	7	505	25	517	2e-15	90.1
rs:WP_046316504	DNA topoisomerase I [Lactobacillus mellifer].	23.16	531	320	18	7	504	25	500	2e-15	89.7
rs:WP_035574515	DNA topoisomerase I, partial [Elioraea tepidiphila].	24.25	536	326	21	4	505	1	490	2e-15	90.1
rs:WP_006647016	topoisomerase I [Photobacterium sp. SKA34].	24.30	539	327	19	7	505	6	503	2e-15	90.1
rs:WP_022628183	DNA topoisomerase I [Bacillus marmarensis].	24.05	524	323	18	7	504	6	480	2e-15	89.7
rs:WP_024521591	DNA topoisomerase I [Lactobacillus plantarum].	26.24	526	307	22	7	505	34	505	2e-15	89.7
rs:WP_031374553	DNA topoisomerase I [Pantoea sp. 3.5.1].	25.93	455	295	16	69	505	68	498	2e-15	90.1
tr:A0A087GIK5_ARAAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.72	625	341	27	36	607	453	1013	2e-15	90.5
tr:W4RI44_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE43578.1};	33.33	156	101	3	378	530	3	158	2e-15	86.7
rs:WP_028669789	DNA topoisomerase I [Saccharospirillum impatiens].	25.24	424	278	15	99	505	108	509	2e-15	90.1
tr:A0A087GIK6_ARAAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.72	625	341	27	36	607	458	1018	2e-15	90.5
rs:WP_008502813	MULTISPECIES: topoisomerase I [Enterobacter].	24.26	540	321	20	7	505	6	498	2e-15	90.1
tr:H7PSL3_STREE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.63	398	239	14	134	504	12	379	2e-15	89.7
rs:WP_023639723	topoisomerase I [Dickeya zeae].	26.20	439	276	17	88	505	95	506	2e-15	90.1
rs:WP_014518576	DNA topoisomerase I [Chlamydia psittaci].	23.72	586	355	22	10	563	2	527	2e-15	90.1
rs:WP_011568344	DNA topoisomerase I [Roseobacter denitrificans].	24.82	552	312	23	4	510	1	494	2e-15	90.1
rs:WP_027553089	DNA topoisomerase I [Bradyrhizobium sp. Cp5.3].	23.84	537	328	20	4	505	1	491	2e-15	90.1
rs:WP_015280197	DNA topoisomerase I [Thioflavicoccus mobilis].	24.77	541	319	22	7	505	4	498	2e-15	90.1
rs:WP_017062103	topoisomerase I [Vibrio crassostreae].	22.78	540	334	19	7	505	6	503	2e-15	90.1
rs:WP_031275716	DNA topoisomerase I [Pseudomonas aeruginosa].	24.95	497	296	21	86	553	58	506	2e-15	89.7
tr:V1DHE5_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	542	329	19	7	505	22	523	2e-15	90.1
rs:XP_003958728	hypothetical protein KAFR_0H01830 [Kazachstania africana CBS 2517].	24.22	607	354	24	7	546	3	570	2e-15	89.7
rs:WP_019845082	topoisomerase I [Dickeya zeae].	26.20	439	276	17	88	505	95	506	2e-15	90.1
rs:WP_023398362	DNA topoisomerase I [Pseudoalteromonas luteoviolacea].	22.74	541	337	16	7	505	6	507	2e-15	90.1
tr:A0A069DDT9_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.28	534	305	24	7	504	6	481	2e-15	89.7
rs:WP_041817766	DNA topoisomerase I [Lactobacillus sanfranciscensis].	23.43	525	321	19	7	504	26	496	2e-15	89.7
rs:WP_015365079	MULTISPECIES: DNA topoisomerase I [Staphylococcus].	25.43	527	310	20	7	504	6	478	2e-15	89.7
rs:WP_017506494	DNA topoisomerase I [alpha proteobacterium L41A].	24.73	562	301	24	7	510	4	501	2e-15	90.1
rs:WP_038881773	DNA topoisomerase I [Serratia marcescens].	26.56	448	263	18	88	505	87	498	2e-15	90.1
tr:G2HS89_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.53	517	296	22	89	568	32	496	2e-15	89.7
rs:WP_045893060	DNA topoisomerase I [Escherichia coli].	24.54	542	317	21	7	505	6	498	2e-15	90.1
rs:WP_040226445	DNA topoisomerase I [Klebsiella pneumoniae].	25.75	435	283	15	88	505	87	498	2e-15	90.1
rs:WP_040176937	DNA topoisomerase I [Klebsiella pneumoniae].	25.75	435	283	15	88	505	87	498	2e-15	90.1
rs:WP_040854215	DNA topoisomerase I [Nocardia niigatensis].	25.00	592	340	23	7	550	1	536	2e-15	90.1
rs:WP_035845126	DNA topoisomerase I [Defluviimonas sp. 20V17].	24.49	543	321	23	4	510	1	490	2e-15	90.1
rs:WP_046175067	DNA topoisomerase I [Domibacillus indicus].	26.65	424	258	16	112	505	82	482	2e-15	89.7
rs:WP_005245924	DNA topoisomerase I [Acinetobacter sp. CIP 51.11].	23.84	537	327	18	7	505	26	518	2e-15	90.1
rs:WP_035685277	DNA topoisomerase I [Flavobacterium reichenbachii].	25.81	527	293	23	7	504	6	463	2e-15	90.1
rs:WP_012386322	DNA topoisomerase I [Beijerinckia indica].	24.09	552	324	21	4	510	1	502	2e-15	90.1
rs:WP_029657060	DNA topoisomerase, partial [Enterococcus faecalis].	28.05	246	165	7	307	544	78	319	3e-15	88.2
rs:WP_025159788	DNA topoisomerase I [Serratia marcescens].	26.01	446	268	17	88	505	87	498	3e-15	90.1
rs:WP_011888870	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	3e-15	89.7
rs:WP_023611066	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	3e-15	89.7
rs:WP_002776977	DNA topoisomerase I [Microcystis aeruginosa].	25.32	549	317	21	5	505	3	506	3e-15	90.1
rs:WP_012410891	DNA topoisomerase I [Nostoc punctiforme].	25.43	519	290	17	89	566	72	534	3e-15	90.1
rs:WP_004930691	MULTISPECIES: DNA topoisomerase I subunit omega [Serratia].	26.56	448	263	18	88	505	87	498	3e-15	90.1
rs:WP_033634748	DNA topoisomerase I [Serratia marcescens].	26.01	446	268	17	88	505	87	498	3e-15	90.1
rs:WP_024468694	DNA topoisomerase I [Treponema pedis].	24.53	534	305	23	7	504	31	502	3e-15	89.7
rs:WP_006586737	DNA topoisomerase I [Lactobacillus jensenii].	25.14	525	314	19	7	505	9	480	3e-15	89.7
rs:WP_016800735	topoisomerase I [Vibrio cyclitrophicus].	22.78	540	334	19	7	505	6	503	3e-15	90.1
tr:D5TVA4_BACT1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.65	421	265	16	112	505	41	440	3e-15	89.7
rs:WP_013045489	DNA topoisomerase I [Candidatus Puniceispirillum marinum].	25.64	546	308	23	4	505	1	492	3e-15	90.1
tr:A0A064C8N5_9STAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.86	531	308	19	7	504	8	480	3e-15	89.7
rs:WP_036025557	DNA topoisomerase I [Bradyrhizobium yuanmingense].	24.02	537	327	20	4	505	1	491	3e-15	90.1
tr:U5UP87_9STAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.10	428	258	16	107	505	34	436	3e-15	89.7
tr:A0A0A5IXC3_CITKO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.30	535	327	19	7	505	6	498	3e-15	90.1
tr:A0A087GIK7_ARAAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.72	625	341	27	36	607	454	1014	3e-15	90.1
rs:WP_010437771	topoisomerase I [Vibrio cyclitrophicus].	22.78	540	334	19	7	505	6	503	3e-15	90.1
rs:WP_033615628	DNA topoisomerase, partial [Enterococcus faecium].	28.05	246	165	7	307	544	78	319	3e-15	88.2
rs:WP_015439910	DNA topoisomerase I [Ilumatobacter coccineus].	25.72	556	310	23	7	510	6	510	3e-15	90.1
rs:WP_024467401	DNA topoisomerase I [Treponema pedis].	24.53	534	305	23	7	504	31	502	3e-15	89.7
rs:WP_037593321	DNA topoisomerase III, partial [Sporosarcina sp. D27].	29.91	224	148	4	329	544	15	237	3e-15	88.2
rs:WP_033647571	DNA topoisomerase I [Serratia marcescens].	26.01	446	268	17	88	505	87	498	3e-15	90.1
rs:WP_039978511	DNA topoisomerase I [Shewanella decolorationis].	23.99	542	329	19	7	505	6	507	3e-15	90.1
tr:J0RMT3_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.04	530	288	24	7	504	13	470	3e-15	89.7
rs:WP_020820769	MULTISPECIES: DNA topoisomerase I [Sphingobium].	24.77	537	312	20	7	505	4	486	3e-15	90.1
rs:WP_043128999	DNA topoisomerase I [Aeromonas media].	22.30	538	337	16	7	505	6	501	3e-15	90.1
rs:WP_025295581	DNA topoisomerase I [Sphingomonas sanxanigenens].	24.76	529	310	22	7	505	4	474	3e-15	89.7
rs:WP_014224989	DNA topoisomerase I [Tannerella forsythia].	25.57	524	303	19	7	504	6	468	3e-15	89.7
rs:WP_017569354	DNA topoisomerase I [Nocardiopsis halotolerans].	24.64	548	329	21	7	505	26	538	3e-15	90.1
rs:WP_021433769	DNA topoisomerase I [[Clostridium] bifermentans].	25.33	525	314	22	7	504	6	479	3e-15	89.7
tr:S7K4H3_CHLPS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.01	558	347	21	38	563	6	518	3e-15	89.7
rs:WP_036514469	DNA topoisomerase I [Nitrincola sp. AK23].	23.12	640	385	26	5	597	4	583	3e-15	90.1
rs:WP_024550709	hypothetical protein, partial [Cronobacter turicensis].	24.95	505	282	18	7	474	6	450	3e-15	88.6
rs:WP_005600147	topoisomerase I [Vibrio scophthalmi].	23.52	523	351	16	7	505	6	503	3e-15	90.1
rs:WP_035691735	DNA topoisomerase I [Flavobacterium sp. F52].	26.04	530	288	24	7	504	6	463	3e-15	89.7
tr:C2T4T6_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.65	421	265	16	112	505	52	451	3e-15	89.7
rs:WP_041412994	DNA topoisomerase I [Shewanella sp. ANA-3].	23.99	542	329	19	7	505	6	507	3e-15	90.1
rs:WP_020965885	DNA topoisomerase I [Treponema pedis].	24.53	534	305	23	7	504	31	502	3e-15	89.7
rs:WP_020367886	DNA topoisomerase I, partial [Staphylococcus epidermidis].	26.18	424	259	14	111	505	1	399	3e-15	89.4
rs:WP_021756983	DNA topoisomerase [Chlamydia pecorum].	24.96	593	344	23	7	563	6	533	3e-15	89.7
rs:WP_032115003	DNA topoisomerase I [Arsenophonus endosymbiont of Nilaparvata lugens].	23.55	535	328	20	7	504	6	496	3e-15	89.7
rs:WP_023260902	DNA topoisomerase III, partial [Salmonella enterica].	24.63	272	188	7	8	271	5	267	3e-15	86.7
rs:WP_004680559	DNA topoisomerase I [Acinetobacter parvus].	23.93	539	324	19	7	505	25	517	3e-15	89.7
rs:XP_010447598	PREDICTED: uncharacterized protein LOC104730175 isoform X1 [Camelina sativa].	27.40	511	293	23	47	505	462	946	3e-15	90.1
rs:WP_017927245	DNA topoisomerase I [Loktanella hongkongensis].	24.80	641	370	28	4	595	1	578	3e-15	90.1
tr:A8AG75_CITK8	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.30	535	327	19	7	505	6	498	3e-15	89.7
rs:WP_040864648	DNA topoisomerase I [Nocardia exalbida].	24.62	593	344	22	7	550	19	557	3e-15	90.1
rs:WP_011017773	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	3e-15	89.7
rs:WP_033747866	hypothetical protein, partial [Helicobacter pylori].	25.33	529	344	22	34	543	24	520	3e-15	89.7
rs:WP_036979408	DNA topoisomerase I [Providencia alcalifaciens].	26.86	443	268	18	88	505	95	506	3e-15	89.7
tr:S7K796_CHLPS	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	25.00	508	318	18	88	563	11	487	3e-15	89.7
rs:WP_038877308	DNA topoisomerase I [Serratia marcescens].	26.35	444	269	17	88	505	87	498	3e-15	89.7
rs:WP_039883922	DNA topoisomerase I [Mogibacterium sp. CM50].	26.82	425	258	15	105	504	71	467	3e-15	89.7
rs:WP_022407582	DNA topoisomerase [Bacillus sp. CAG:988].	24.48	527	314	20	7	506	6	475	3e-15	89.7
rs:WP_018704610	hypothetical protein [Anaeromusa acidaminophila].	23.40	530	323	17	5	504	3	479	3e-15	89.4
rs:WP_026858406	DNA topoisomerase I [Jeotgalicoccus psychrophilus].	25.36	422	274	15	107	505	77	480	3e-15	89.7
rs:WP_007505175	DNA topoisomerase I [Caldalkalibacillus thermarum].	24.39	533	310	20	7	504	6	480	3e-15	89.7
rs:WP_033610393	DNA topoisomerase I [Lactobacillus paraplantarum].	26.00	527	307	22	7	505	34	505	3e-15	89.7
rs:WP_041417181	DNA topoisomerase I [Shewanella sp. MR-7].	23.99	542	329	19	7	505	6	507	3e-15	89.7
rs:WP_035517327	DNA topoisomerase I [Pseudohaliea rubra].	24.43	438	285	16	88	505	100	511	3e-15	89.7
rs:WP_039468103	DNA topoisomerase I [Photobacterium gaetbulicola].	25.97	462	285	20	69	505	74	503	3e-15	89.7
rs:WP_003869178	DNA topoisomerase I [Thermoanaerobacter ethanolicus].	23.86	570	341	20	7	553	6	505	3e-15	89.7
rs:WP_019643573	hypothetical protein [Novispirillum itersonii].	24.49	539	322	21	4	505	1	491	3e-15	90.1
rs:WP_044203746	DNA topoisomerase I [Chlamydia psittaci].	23.64	550	343	21	46	563	5	509	3e-15	89.7
rs:WP_034566021	DNA topoisomerase I [Helicobacter bilis].	25.51	439	277	16	109	515	75	495	3e-15	89.7
rs:XP_010447600	PREDICTED: uncharacterized protein LOC104730175 isoform X3 [Camelina sativa].	27.40	511	293	23	47	505	461	945	3e-15	90.1
tr:U2LFN4_PORGN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.36	535	301	20	7	505	32	493	3e-15	89.7
rs:WP_001286963	MULTISPECIES: DNA topoisomerase I [Bacillus].	25.65	421	265	16	112	505	82	481	3e-15	89.7
rs:WP_036863604	DNA topoisomerase I [Porphyromonas sp. COT-108 OH2963].	24.76	521	311	17	7	504	6	468	3e-15	89.7
rs:WP_036788982	DNA topoisomerase I [Porphyromonas canoris].	24.76	521	311	17	7	504	6	468	3e-15	89.7
rs:WP_010963054	DNA topoisomerase I [Wolbachia endosymbiont of Drosophila melanogaster].	25.00	460	291	15	80	504	46	486	3e-15	89.7
rs:WP_024111510	DNA topoisomerase I [Propionimicrobium sp. BV2F7].	22.63	548	338	21	7	505	8	518	3e-15	89.7
rs:WP_034790972	DNA topoisomerase I [Ewingella americana].	24.67	454	302	14	69	505	68	498	3e-15	89.7
rs:WP_022079531	DNA topoisomerase [Acetobacter sp. CAG:267].	25.66	534	305	22	7	504	4	481	3e-15	89.7
rs:XP_010447599	PREDICTED: uncharacterized protein LOC104730175 isoform X2 [Camelina sativa].	27.40	511	293	23	47	505	462	946	3e-15	90.1
rs:WP_037383189	DNA topoisomerase I [Smithella sp. SCADC].	24.86	547	312	22	7	510	6	496	3e-15	89.7
rs:WP_022064027	DNA topoisomerase [Alistipes sp. CAG:157].	22.52	524	320	16	7	505	19	481	3e-15	89.7
rs:WP_026061366	DNA topoisomerase I [Rhodococcus rhodochrous].	24.02	587	349	22	7	550	19	551	3e-15	89.7
tr:F8E529_FLESM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.75	532	327	20	107	606	89	584	3e-15	89.7
rs:WP_018274720	topoisomerase I [Teredinibacter turnerae].	23.08	533	348	17	7	505	6	510	3e-15	89.7
rs:WP_001727616	DNA topoisomerase III, partial [Salmonella enterica].	24.63	272	188	7	8	271	5	267	3e-15	86.7
rs:WP_009381719	DNA topoisomerase I [Staphylococcus massiliensis].	24.11	531	314	18	7	505	6	479	3e-15	89.4
rs:WP_021677229	DNA topoisomerase I [Porphyromonas gingivalis].	23.36	535	301	20	7	505	5	466	3e-15	89.7
rs:WP_020583560	hypothetical protein [Endozoicomonas elysicola].	24.37	439	287	15	90	505	94	510	3e-15	89.7
tr:Q0HW50_SHESR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	542	329	19	7	505	22	523	3e-15	89.7
rs:WP_036845096	MULTISPECIES: DNA topoisomerase I [Porphyromonas].	24.76	521	311	17	7	504	6	468	3e-15	89.7
rs:WP_023056255	DNA topoisomerase I [Peptoniphilus sp. BV3C26].	24.14	522	323	15	7	504	6	478	3e-15	89.4
tr:X0QTV8_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.94	421	274	14	107	505	123	523	3e-15	89.0
rs:WP_046338444	DNA topoisomerase I [Pasteurella multocida].	25.28	447	270	16	88	505	93	504	3e-15	89.7
rs:WP_027712113	DNA topoisomerase I [Dickeya chrysanthemi].	25.99	431	266	18	99	505	99	500	3e-15	89.7
rs:WP_046324810	DNA topoisomerase I [Lactobacillus melliventris].	23.33	523	326	17	7	505	15	486	3e-15	89.4
rs:WP_044623863	DNA topoisomerase I [Photobacterium gaetbulicola].	25.97	462	285	20	69	505	74	503	3e-15	89.7
rs:WP_013182761	DNA topoisomerase I [Waddlia chondrophila].	24.27	585	346	21	3	553	2	523	3e-15	89.7
rs:WP_023847008	DNA topoisomerase I [Porphyromonas gingivalis].	23.36	535	301	20	7	505	5	466	3e-15	89.7
rs:WP_019975010	DNA topoisomerase I [Empedobacter brevis].	23.75	518	316	19	7	504	6	464	3e-15	89.7
rs:WP_036825650	DNA topoisomerase I [Porphyromonadaceae bacterium COT-184 OH4590].	24.86	527	301	20	7	504	5	465	3e-15	89.7
rs:WP_033775410	hypothetical protein [Helicobacter pylori].	25.33	529	344	22	34	543	19	515	3e-15	89.7
rs:WP_012461831	DNA topoisomerase I [Orientia tsutsugamushi].	26.04	530	311	23	7	504	4	484	3e-15	89.7
tr:J5U251_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.82	425	258	15	105	504	48	444	3e-15	89.4
rs:WP_033843509	DNA topoisomerase I [Geobacillus subterraneus].	23.15	622	380	21	7	598	6	559	3e-15	89.4
rs:WP_012340540	topoisomerase I [Histophilus somni].	25.45	448	268	16	88	505	93	504	3e-15	89.7
rs:WP_042128949	DNA topoisomerase I [Paenibacillus sp. FSL R5-0345].	24.19	525	322	19	7	504	6	481	3e-15	89.4
rs:WP_019210093	topoisomerase I [Yersinia massiliensis].	26.32	437	278	16	88	505	94	505	3e-15	89.7
rs:WP_013602276	DNA topoisomerase I [Arthrobacter phenanthrenivorans].	24.48	572	310	21	7	510	12	529	3e-15	89.7
rs:WP_016856973	topoisomerase I [Candidatus Hamiltonella defensa].	23.77	547	317	20	7	505	6	500	3e-15	89.7
rs:WP_002436312	DNA topoisomerase I [Staphylococcus capitis].	24.86	531	308	19	7	504	6	478	3e-15	89.4
rs:WP_001516492	MULTISPECIES: topoisomerase I [Escherichia].	24.79	468	294	17	64	505	63	498	3e-15	89.7
rs:WP_031596742	DNA topoisomerase I, partial [Ferrovum myxofaciens].	25.23	535	315	22	7	504	6	492	3e-15	89.7
rs:WP_004756177	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	23.93	539	324	19	7	505	25	517	3e-15	89.7
rs:WP_045915940	DNA topoisomerase I [Orientia tsutsugamushi].	26.04	530	311	23	7	504	4	484	3e-15	89.7
rs:WP_025774465	DNA topoisomerase I [Moorella thermoacetica].	25.00	564	324	20	5	540	4	496	3e-15	89.4
rs:WP_016514708	DNA topoisomerase 1 [Microcystis aeruginosa].	25.14	549	318	21	5	505	3	506	3e-15	89.7
rs:WP_009880713	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	3e-15	89.4
rs:WP_001700602	DNA topoisomerase III, partial [Salmonella enterica].	24.63	272	188	7	8	271	5	267	3e-15	86.3
tr:A0KVZ3_SHESA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	542	329	19	7	505	22	523	3e-15	89.7
rs:WP_012777656	DNA topoisomerase I [Methylotenera mobilis].	25.38	532	318	19	7	504	5	491	3e-15	89.7
rs:WP_028719490	DNA topoisomerase I [Paracoccus yeei].	24.15	530	323	17	4	505	1	479	3e-15	89.7
rs:WP_023350396	MULTISPECIES: DNA topoisomerase I [Staphylococcus].	24.86	531	308	19	7	504	6	478	3e-15	89.4
tr:C2P2H6_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.65	421	265	16	112	505	52	451	3e-15	89.4
rs:WP_003645027	DNA topoisomerase [Lactobacillus plantarum].	25.76	524	312	21	7	505	34	505	3e-15	89.4
rs:WP_038199520	DNA topoisomerase I [Wolbachia pipientis].	25.00	460	291	15	80	504	46	486	3e-15	89.7
rs:WP_002750250	DNA topoisomerase I [Microcystis aeruginosa].	25.14	549	318	21	5	505	3	506	3e-15	89.7
tr:I8R0U8_9THEO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952}; Flags: Precursor;	23.86	570	341	20	7	553	6	505	3e-15	89.4
rs:WP_024910790	DNA topoisomerase I [Serratia fonticola].	26.68	446	265	18	88	505	87	498	3e-15	89.7
rs:WP_002735765	DNA topoisomerase I [Microcystis aeruginosa].	25.14	549	318	21	5	505	3	506	3e-15	89.7
rs:WP_042535048	DNA topoisomerase I [Oceanobacillus oncorhynchi].	22.86	525	331	15	7	505	6	482	3e-15	89.4
tr:T3QMB3_PEPDI	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EQG75830.1};	31.72	186	117	6	7	190	6	183	3e-15	85.5
rs:WP_022191330	DNA topoisomerase [Firmicutes bacterium CAG:240].	24.12	568	343	20	7	553	9	509	3e-15	89.4
gpu:AP013045_1345	DNA topoisomerase I [Tannerella forsythia KS16]	24.71	611	345	23	7	570	6	548	3e-15	89.4
tr:E0QIP1_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.56	539	324	19	7	512	8	491	3e-15	89.4
rs:WP_005200284	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	24.12	539	323	19	7	505	25	517	3e-15	89.7
rs:WP_004674582	DNA topoisomerase I [Acinetobacter parvus].	23.93	539	324	19	7	505	25	517	3e-15	89.7
rs:WP_045719125	DNA topoisomerase III, partial [Salmonella enterica].	24.63	272	188	7	8	271	5	267	3e-15	86.3
rs:WP_006661696	DNA topoisomerase I subunit omega [Providencia alcalifaciens].	26.86	443	268	18	88	505	95	506	3e-15	89.7
rs:WP_042078125	DNA topoisomerase I [Aeromonas sanarellii].	22.41	540	334	18	7	505	6	501	3e-15	89.7
rs:WP_031838147	hypothetical protein [Staphylococcus aureus].	29.10	244	159	6	5	243	3	237	3e-15	85.9
rs:WP_011927356	DNA topoisomerase I [Bradyrhizobium sp. ORS 278].	23.69	536	330	20	4	505	1	491	3e-15	89.7
rs:WP_024102825	DNA topoisomerase I [Rhodococcus pyridinivorans].	24.02	587	349	22	7	550	19	551	3e-15	89.7
rs:WP_033022990	DNA topoisomerase I [Geobacillus sp. G1w1].	22.88	625	378	21	7	598	6	559	3e-15	89.4
rs:WP_034635714	DNA topoisomerase I [Bacillus manliponensis].	25.71	420	266	14	112	505	82	481	3e-15	89.4
rs:WP_006812921	topoisomerase I [Providencia rustigianii].	26.47	442	271	16	88	505	94	505	3e-15	89.7
rs:WP_046445616	DNA topoisomerase I [Alistipes sp. N15.MGS-157].	22.52	524	320	16	7	505	19	481	3e-15	89.4
tr:J7AQD8_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.29	251	161	8	278	515	18	262	3e-15	86.3
tr:R2QYG4_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.41	259	175	7	295	544	2	256	3e-15	86.3
rs:WP_036963747	DNA topoisomerase I [Providencia alcalifaciens].	26.86	443	268	18	88	505	95	506	3e-15	89.7
rs:WP_041205259	DNA topoisomerase I [Aeromonas media].	22.30	538	337	16	7	505	6	501	3e-15	89.7
rs:WP_047267500	DNA topoisomerase I [Marinitoga sp. 1197].	25.57	528	303	22	7	505	9	475	3e-15	89.4
rs:WP_043895451	DNA topoisomerase I [Porphyromonas gingivalis].	23.36	535	301	20	7	505	5	466	3e-15	89.4
rs:WP_023250895	DNA topoisomerase III, partial [Salmonella enterica].	24.63	272	188	7	8	271	5	267	3e-15	86.3
rs:WP_036975684	DNA topoisomerase I [Providencia alcalifaciens].	26.86	443	268	18	88	505	95	506	3e-15	89.7
rs:WP_026303763	DNA topoisomerase I [Gordonia kroppenstedtii].	24.31	576	344	20	7	535	15	545	3e-15	89.7
rs:WP_004121251	topoisomerase I [Klebsiella oxytoca].	24.30	535	327	19	7	505	6	498	3e-15	89.7
rs:WP_029675922	DNA topoisomerase, partial [Enterococcus faecalis].	28.15	238	159	7	315	544	1	234	3e-15	86.7
rs:WP_041262638	DNA topoisomerase I [Flexistipes sinusarabici].	25.75	532	327	20	107	606	71	566	3e-15	89.4
rs:WP_046466609	DNA topoisomerase I [Staphylococcus pasteuri].	25.19	528	310	20	7	504	6	478	4e-15	89.4
rs:WP_021731562	DNA topoisomerase I [Lactobacillus plantarum].	26.24	526	307	22	7	505	34	505	4e-15	89.4
rs:WP_015325136	topoisomerase IA [Methanomethylovorans hollandica].	23.80	563	360	19	7	548	18	532	4e-15	89.4
rs:WP_045106988	DNA topoisomerase I [Legionella hackeliae].	24.58	537	319	17	7	505	6	494	4e-15	89.4
rs:WP_025756584	MULTISPECIES: DNA topoisomerase I [Enterobacter].	23.83	533	332	18	7	505	6	498	4e-15	89.4
tr:H0JSA9_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.02	587	349	22	7	550	19	551	4e-15	89.7
rs:WP_039586736	DNA topoisomerase I [Rhodococcus sp. Chr-9].	24.02	587	349	22	7	550	19	551	4e-15	89.7
rs:WP_024018204	DNA topoisomerase I [Sphingobium sp. C100].	25.72	521	315	18	7	505	4	474	4e-15	89.4
rs:WP_015207494	DNA topoisomerase I [Cylindrospermum stagnale].	24.55	444	286	15	91	505	66	489	4e-15	89.4
rs:WP_036891125	hypothetical protein, partial [Prevotella corporis].	27.78	216	133	6	331	534	1	205	4e-15	87.4
rs:WP_012498988	DNA topoisomerase I [Chloroherpeton thalassium].	24.07	536	311	21	7	500	20	501	4e-15	89.4
tr:A0A0B8NR25_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.35	460	295	16	69	505	74	503	4e-15	89.4
rs:WP_026016696	DNA topoisomerase I [Catenovulum agarivorans].	26.30	441	275	16	88	505	91	504	4e-15	89.4
rs:WP_004396182	MULTISPECIES: DNA topoisomerase I [Thermoanaerobacter].	23.86	570	341	20	7	553	6	505	4e-15	89.4
rs:WP_015481981	DNA topoisomerase I [Polaribacter sp. MED152].	25.48	526	296	22	7	504	6	463	4e-15	89.4
tr:F9PVG5_9STRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	26.30	327	208	10	198	504	30	343	4e-15	89.0
rs:WP_011010569	DNA topoisomerase I [Clostridium perfringens].	24.76	525	318	20	7	505	6	479	4e-15	89.4
rs:WP_026559364	DNA topoisomerase I [Bacillus sp. J37].	25.12	418	269	11	112	504	82	480	4e-15	89.4
rs:WP_024362045	MULTISPECIES: DNA topoisomerase I [Lysinibacillus].	25.53	427	263	15	109	504	79	481	4e-15	89.4
gpu:AP014685_9795	DNA topoisomerase I [Bradyrhizobium diazoefficiens]	24.02	537	327	20	4	505	1	491	4e-15	89.7
rs:WP_041999769	DNA topoisomerase I [Aeromonas bivalvium].	22.01	536	341	17	7	505	6	501	4e-15	89.4
rs:WP_004101389	MULTISPECIES: topoisomerase I [Klebsiella].	24.21	537	325	19	7	505	6	498	4e-15	89.4
rs:WP_045677419	DNA topoisomerase I [Desulfatitalea sp. BRH_c12].	24.64	556	323	21	1	516	1	500	4e-15	89.4
rs:WP_011278207	DNA topoisomerase I [Sulfolobus acidocaldarius].	25.91	548	326	23	38	564	48	536	4e-15	89.4
rs:WP_004763747	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	23.93	539	324	19	7	505	25	517	4e-15	89.4
rs:WP_041119071	DNA topoisomerase I [Enterococcus gallinarum].	23.95	526	321	18	7	504	7	481	4e-15	89.4
rs:WP_001286961	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	25.30	419	269	14	112	505	82	481	4e-15	89.4
rs:WP_012988731	topoisomerase I [Xenorhabdus bovienii].	24.73	461	293	16	69	505	66	496	4e-15	89.4
rs:WP_024970798	DNA topoisomerase I [Microcystis aeruginosa].	25.14	549	318	21	5	505	3	506	4e-15	89.4
rs:WP_043025818	DNA topoisomerase I [Streptococcus equi].	23.31	519	326	18	7	504	30	497	4e-15	89.4
rs:WP_025730271	DNA topoisomerase I [Atopobacter phocae].	23.61	521	329	18	7	504	7	481	4e-15	89.4
rs:WP_037217231	DNA topoisomerase I [Rhodococcus sp. R04].	24.02	587	349	22	7	550	27	559	4e-15	89.7
rs:WP_008778583	DNA topoisomerase III [Parabacteroides sp. 20_3].	20.88	613	407	19	4	590	1	561	4e-15	89.0
rs:WP_040445183	DNA topoisomerase I [[Eubacterium] yurii].	23.75	539	323	19	7	512	5	488	4e-15	89.4
rs:WP_023292242	DNA topoisomerase 1 [Enterobacter cloacae].	24.26	540	321	20	7	505	6	498	4e-15	89.4
rs:WP_037406881	DNA topoisomerase I [Snodgrassella alvi].	25.75	536	309	22	7	505	6	489	4e-15	89.4
rs:WP_046039372	DNA topoisomerase I [Lactobacillus plantarum].	26.24	526	307	22	7	505	34	505	4e-15	89.4
rs:WP_045125034	conjugal transfer protein TraB, partial [Acinetobacter pittii].	25.59	379	239	14	97	460	71	421	4e-15	88.2
rs:WP_026722768	DNA topoisomerase I [Fischerella sp. PCC 9431].	25.11	450	278	16	89	504	64	488	4e-15	89.4
rs:WP_044430780	DNA topoisomerase I [Lactobacillus plantarum].	25.76	524	312	21	7	505	34	505	4e-15	89.4
rs:WP_047263941	DNA topoisomerase I [Candidatus Liberibacter africanus].	25.09	546	311	25	4	505	1	492	4e-15	89.4
rs:WP_044810431	DNA topoisomerase I [Bacillus cereus].	25.30	419	269	14	112	505	82	481	4e-15	89.4
rs:WP_027537100	DNA topoisomerase I [Bradyrhizobium sp. URHA0002].	24.07	536	329	19	4	505	1	492	4e-15	89.4
rs:WP_014924677	topoisomerase I [Gordonia sp. KTR9].	25.00	444	275	15	7	425	6	416	4e-15	89.4
rs:WP_032549444	DNA topoisomerase I [Vibrio fortis].	23.32	549	320	21	7	505	6	503	4e-15	89.4
tr:C7YE99_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.05	246	165	7	307	544	59	300	4e-15	88.6
rs:WP_006658706	topoisomerase I [Providencia alcalifaciens].	26.86	443	268	18	88	505	95	506	4e-15	89.4
rs:WP_026809853	DNA topoisomerase I [Arenibacter latericius].	24.86	519	310	20	7	504	6	465	4e-15	89.4
rs:WP_032204508	DNA topoisomerase I [Escherichia coli].	24.11	535	328	20	7	505	6	498	4e-15	89.4
rs:WP_019144471	DNA topoisomerase I [Aeromicrobium massiliense].	24.46	552	331	18	1	505	1	513	4e-15	89.4
rs:WP_025724508	DNA topoisomerase I [Acholeplasma granularum].	25.30	585	345	24	26	587	12	527	4e-15	89.0
rs:WP_038208563	DNA topoisomerase I [Xenorhabdus bovienii].	25.00	460	293	17	69	505	66	496	4e-15	89.4
rs:WP_002450562	DNA topoisomerase I [Staphylococcus warneri].	25.61	531	304	21	7	504	6	478	4e-15	89.0
rs:WP_001286960	MULTISPECIES: DNA topoisomerase I [Bacillus].	25.65	421	265	16	112	505	82	481	4e-15	89.0
rs:WP_032124739	DNA topoisomerase I [Chlamydia sp. 'Diamant'].	23.28	537	329	20	7	504	6	498	4e-15	89.4
rs:WP_003458449	DNA topoisomerase I [Clostridium perfringens].	24.57	525	319	20	7	505	6	479	4e-15	89.4
rs:WP_017346259	topoisomerase I [Pantoea sp. A4].	24.50	547	311	21	7	505	6	498	4e-15	89.4
rs:WP_022144615	DNA topoisomerase [Ruminococcus sp. CAG:563].	25.65	542	301	25	7	505	5	487	4e-15	89.4
rs:WP_039411736	DNA topoisomerase I [Microbacterium hominis].	23.45	550	326	17	7	505	13	518	4e-15	89.4
rs:WP_020087305	DNA topoisomerase I [Hyphomicrobium zavarzinii].	26.16	451	262	18	107	505	75	506	4e-15	89.4
rs:WP_044344627	hypothetical protein, partial [Pseudomonas meliae].	26.76	441	264	17	93	504	61	471	4e-15	89.0
rs:WP_033097900	DNA topoisomerase I [Rhodococcus sp. p52].	24.02	587	349	22	7	550	27	559	4e-15	89.4
tr:T1ABF9_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD38224.1}; Flags: Fragment;	23.95	526	304	19	7	491	6	476	4e-15	88.6
rs:WP_038506612	DNA topoisomerase [Leptospirillum ferriphilum].	23.78	555	317	24	7	512	2	499	4e-15	89.4
rs:WP_026234060	DNA topoisomerase I [Thermus oshimai].	25.44	456	295	16	80	505	63	503	4e-15	89.4
rs:WP_039836543	DNA topoisomerase I [Paenibacillus sonchi].	24.34	530	315	22	7	504	6	481	4e-15	89.0
rs:WP_002384820	type 1 topoisomerase [Enterococcus faecalis].	28.05	246	165	7	307	544	48	289	4e-15	88.2
rs:WP_001390153	DNA topoisomerase I [Escherichia coli].	24.63	544	314	22	7	505	6	498	4e-15	89.4
tr:F8XQZ5_9GAMM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGQ62138.1}; Flags: Fragment;	29.41	204	131	4	365	559	10	209	4e-15	87.0
rs:WP_004800148	DNA topoisomerase I [Acinetobacter sp. CIP 102637].	23.75	539	325	19	7	505	25	517	4e-15	89.4
rs:WP_046538212	DNA topoisomerase I [Clostridiales bacterium PH28_bin88].	25.23	535	307	21	7	504	11	489	4e-15	89.0
rs:WP_013052041	topoisomerase I [Shewanella violacea].	22.43	544	335	18	7	505	6	507	4e-15	89.4
rs:WP_031897078	DNA topoisomerase III, partial [Staphylococcus aureus].	29.29	239	155	6	5	238	3	232	4e-15	85.5
rs:WP_013146985	DNA topoisomerase I [Methylotenera versatilis].	24.86	535	317	21	7	504	5	491	4e-15	89.4
rs:WP_003419396	DNA topoisomerase I [Peptoclostridium difficile].	26.78	534	299	25	5	504	4	479	4e-15	89.0
rs:WP_008214692	DNA topoisomerase I [Lactobacillus parafarraginis].	26.01	419	270	15	107	504	94	493	4e-15	89.0
rs:WP_025148338	DNA topoisomerase I [Bacillus sp. H1a].	26.01	419	266	14	112	505	82	481	4e-15	89.0
rs:WP_006588265	DNA topoisomerase I [Lactobacillus jensenii].	25.05	523	317	19	7	505	9	480	4e-15	89.0
rs:WP_038259937	DNA topoisomerase I [Xenorhabdus cabanillasii].	26.12	448	265	17	88	505	87	498	4e-15	89.4
rs:WP_013175125	DNA topoisomerase I [Syntrophothermus lipocalidus].	23.25	628	389	21	7	607	3	564	4e-15	89.0
rs:WP_021392297	DNA topoisomerase I [Peptoclostridium difficile].	26.42	530	306	25	5	504	4	479	4e-15	89.0
rs:WP_008184655	DNA topoisomerase I [Rhodobacteraceae bacterium HTCC2150].	24.91	534	317	24	4	505	1	482	4e-15	89.4
rs:WP_044424461	conjugal transfer protein TraB, partial [Acinetobacter pittii].	25.59	379	239	14	97	460	71	421	4e-15	87.8
rs:WP_040794088	DNA topoisomerase I [Nocardia higoensis].	24.45	593	345	22	7	550	1	539	4e-15	89.4
rs:WP_017099940	topoisomerase I [Vibrio tasmaniensis].	22.96	540	333	19	7	505	6	503	4e-15	89.4
rs:WP_002353995	DNA topoisomerase, partial [Enterococcus faecium].	30.00	230	142	8	278	494	38	261	4e-15	85.9
rs:WP_015081448	DNA topoisomerase I [Anabaena sp. 90].	24.59	545	326	17	5	505	3	506	4e-15	89.4
rs:WP_039958145	DNA topoisomerase I [Rhodococcus pyridinivorans].	24.02	587	349	22	7	550	27	559	4e-15	89.4
rs:WP_013992519	DNA topoisomerase I [Zobellia galactanivorans].	24.08	519	314	17	7	504	6	465	4e-15	89.4
rs:WP_012800727	topoisomerase I [Kangiella koreensis].	25.63	437	281	15	88	505	99	510	4e-15	89.4
rs:WP_003644423	DNA topoisomerase I [Lactobacillus plantarum].	25.76	524	312	21	7	505	34	505	4e-15	89.0
rs:WP_024083914	DNA topoisomerase I [Sulfolobus acidocaldarius].	25.60	586	351	25	5	564	10	536	4e-15	89.0
rs:WP_005327151	DNA topoisomerase I [Corynebacterium tuberculostearicum].	24.90	526	304	24	40	505	30	524	4e-15	89.4
rs:WP_032881097	DNA topoisomerase I [Pseudomonas sp. BRG-100].	24.66	519	325	18	38	539	25	494	4e-15	89.0
rs:WP_045127195	DNA topoisomerase I [Photobacterium angustum].	24.12	539	328	19	7	505	6	503	4e-15	89.4
rs:WP_021375035	DNA topoisomerase I [Peptoclostridium difficile].	26.59	534	300	25	5	504	4	479	4e-15	89.0
rs:WP_037415810	DNA topoisomerase I [Serratia grimesii].	25.91	467	280	18	69	505	70	500	4e-15	89.4
rs:WP_020434731	DNA topoisomerase [Clostridium sp. CAG:1000].	25.00	524	315	23	7	506	5	474	4e-15	89.0
rs:WP_027671233	DNA topoisomerase I [Rheinheimera baltica].	24.11	531	329	19	7	505	6	494	4e-15	89.4
rs:WP_039532272	DNA topoisomerase I [Ruegeria sp. ANG-S4].	24.43	569	315	24	4	510	1	516	4e-15	89.4
rs:WP_039447261	DNA topoisomerase I [Pedobacter glucosidilyticus].	25.05	455	280	16	80	505	48	470	4e-15	89.4
rs:WP_005226653	DNA topoisomerase I [Acinetobacter sp. NIPH 1847].	25.73	443	271	16	88	505	108	517	4e-15	89.4
rs:WP_032583635	DNA topoisomerase I, partial [Bacteroides fragilis].	26.77	269	176	8	201	463	5	258	4e-15	85.9
rs:WP_045651823	DNA topoisomerase I [Gammaproteobacteria bacterium BRH_c0].	24.94	433	289	13	88	505	98	509	4e-15	89.4
rs:WP_038582249	DNA topoisomerase I [Corynebacterium glutamicum].	24.89	474	281	18	86	505	80	532	4e-15	89.4
rs:WP_027773285	DNA topoisomerase I [Streptomyces sp. CNQ329].	25.65	460	271	17	97	505	86	525	4e-15	89.4
tr:D5S2T3_PEPDI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.78	534	299	25	5	504	10	485	4e-15	89.0
rs:WP_045352264	DNA topoisomerase I [Lactobacillus plantarum].	25.76	524	312	21	7	505	34	505	4e-15	89.0
rs:WP_026692501	DNA topoisomerase I [Bacillus kribbensis].	26.00	423	259	16	112	504	82	480	4e-15	89.0
rs:WP_009052420	DNA topoisomerase I [Thermoanaerobacter sp. X561].	23.86	570	341	20	7	553	6	505	4e-15	89.0
tr:C2UZ72_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.30	419	269	14	112	505	52	451	4e-15	89.0
rs:WP_033185381	DNA topoisomerase I [Pseudoalteromonas sp. PLSV].	23.75	539	333	18	7	505	6	506	4e-15	89.4
tr:A0A0A6PH49_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	540	313	21	7	505	6	494	4e-15	89.0
rs:WP_018416638	topoisomerase I [Teredinibacter turnerae].	23.08	533	348	17	7	505	6	510	4e-15	89.4
tr:L9PS42_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELX66474.1};	26.67	345	206	13	5	333	3	316	4e-15	86.3
rs:WP_044551634	DNA topoisomerase I [Serratia liquefaciens].	25.55	458	293	16	69	505	68	498	4e-15	89.4
rs:WP_009636003	topoisomerase I [Serratia sp. M24T3].	24.68	462	292	17	69	505	68	498	4e-15	89.4
rs:WP_003126977	MULTISPECIES: DNA topoisomerase I [Enterococcus].	23.95	526	321	18	7	504	7	481	4e-15	89.0
rs:WP_022676334	DNA topoisomerase I [Novosphingobium sp. B-7].	26.32	532	301	23	7	505	4	477	4e-15	89.4
tr:A0A0E1RBZ5_ENTFL	SubName: Full=DNA Topoisomerase family protein {ECO:0000313|EMBL:CCO71514.1};	28.05	246	165	7	307	544	75	316	4e-15	88.2
rs:WP_011575153	topoisomerase I [Pseudoalteromonas atlantica].	23.56	539	334	18	7	505	6	506	4e-15	89.4
rs:WP_021957116	DNA topoisomerase [Eubacterium sp. CAG:115].	24.48	531	315	19	7	505	5	481	4e-15	89.0
rs:WP_042020602	DNA topoisomerase I [Aeromonas sobria].	22.49	538	336	17	7	505	6	501	4e-15	89.4
rs:WP_020827133	topoisomerase I [Serratia liquefaciens].	25.55	458	293	16	69	505	68	498	4e-15	89.4
rs:WP_044029693	DNA topoisomerase I [Corynebacterium glutamicum].	24.89	474	281	18	86	505	80	532	5e-15	89.4
rs:WP_029685549	DNA topoisomerase I [Tatumella saanichensis].	25.51	439	279	16	88	505	87	498	5e-15	89.4
rs:WP_031895793	DNA topoisomerase III, partial [Staphylococcus aureus].	30.41	194	129	4	356	544	2	194	5e-15	86.7
rs:WP_027970598	DNA topoisomerase I [Streptococcus castoreus].	23.71	523	319	18	7	504	30	497	5e-15	89.0
rs:WP_001286962	DNA topoisomerase I [Bacillus cereus].	25.30	419	269	14	112	505	82	481	5e-15	89.0
rs:WP_046210735	DNA topoisomerase I [Nautella sp. ECSMB14104].	25.00	568	310	28	4	510	1	513	5e-15	89.4
tr:Q08Q69_STIAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.98	570	323	23	7	516	72	585	5e-15	89.0
rs:WP_040380902	hypothetical protein, partial [Deinococcus aquatilis].	23.03	547	339	20	5	514	3	504	5e-15	88.6
rs:WP_039626232	DNA topoisomerase I [Vibrio ichthyoenteri].	24.29	457	299	16	69	505	74	503	5e-15	89.4
tr:G2KTQ4_LACSM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.47	524	320	19	8	504	1	470	5e-15	89.0
rs:WP_002645950	DNA topoisomerase I [Planctomyces maris].	23.42	538	339	18	7	505	10	513	5e-15	89.4
rs:WP_045998281	DNA topoisomerase I [Loktanella sp. S4079].	26.18	550	316	24	4	515	1	498	5e-15	89.4
rs:WP_042189457	DNA topoisomerase I [Paenibacillus sp. FSL H7-0737].	24.43	528	317	20	7	504	6	481	5e-15	89.0
rs:WP_016352460	DNA topoisomerase I [Spiribacter salinus].	23.43	559	313	18	7	505	6	509	5e-15	89.0
rs:WP_024791594	DNA topoisomerase I [Lebetimonas sp. JS032].	25.43	519	316	19	7	505	6	473	5e-15	89.0
rs:WP_012145384	MULTISPECIES: topoisomerase I [Serratia].	25.97	439	277	16	88	505	87	498	5e-15	89.4
rs:WP_021354089	hypothetical protein, partial [Corynebacterium pseudodiphtheriticum].	30.26	195	126	5	45	236	3	190	5e-15	85.1
rs:WP_029087405	DNA topoisomerase I [Brevundimonas aveniformis].	25.28	542	322	25	4	510	1	494	5e-15	89.0
rs:WP_038810540	DNA topoisomerase I [Peptoclostridium difficile].	26.59	534	300	25	5	504	4	479	5e-15	89.0
rs:WP_024108762	topoisomerase I [Dickeya dianthicola].	24.72	441	280	16	88	505	89	500	5e-15	89.0
rs:WP_036882142	DNA topoisomerase I, partial [Prevotella nigrescens].	26.67	345	206	13	5	333	3	316	5e-15	86.3
rs:WP_001382542	DNA topoisomerase I [Escherichia coli].	23.99	542	320	21	7	505	6	498	5e-15	89.0
tr:Q1PYZ6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.77	541	315	23	2	505	4	489	5e-15	89.0
rs:WP_006718217	topoisomerase I [Aggregatibacter segnis].	25.73	447	268	17	88	505	93	504	5e-15	89.0
rs:WP_045152232	DNA topoisomerase III, partial [Escherichia coli].	29.82	228	136	5	338	543	1	226	5e-15	87.8
rs:WP_028171575	MULTISPECIES: DNA topoisomerase I [Bradyrhizobium].	24.02	537	327	20	4	505	1	491	5e-15	89.4
rs:WP_004112425	topoisomerase I [Klebsiella oxytoca].	24.21	537	325	19	7	505	6	498	5e-15	89.0
rs:WP_039483662	DNA topoisomerase I [Vibrio sinaloensis].	24.07	457	300	16	69	505	74	503	5e-15	89.0
rs:WP_046465282	DNA topoisomerase I [Staphylococcus equorum].	25.24	527	311	21	7	504	6	478	5e-15	89.0
rs:WP_024105897	topoisomerase I [Dickeya dianthicola].	24.15	439	285	15	88	505	89	500	5e-15	89.0
rs:WP_015191856	DNA topoisomerase I [Stanieria cyanosphaera].	24.37	517	303	19	91	568	74	541	5e-15	89.0
rs:WP_038480781	DNA topoisomerase I [Bacillus lehensis].	22.87	634	385	24	7	607	6	568	5e-15	89.0
rs:WP_009883364	DNA topoisomerase I [Brevibacterium linens].	23.96	551	327	19	7	505	12	522	5e-15	89.4
rs:WP_023060017	DNA topoisomerase I [Peptoniphilus sp. BV3AC2].	24.33	522	322	17	7	504	6	478	5e-15	89.0
rs:XP_010257889	PREDICTED: DNA topoisomerase 3-alpha [Nelumbo nucifera].	25.96	520	295	21	47	505	425	915	5e-15	89.4
rs:WP_020189432	DNA topoisomerase I [Kurthia sp. Dielmo].	27.74	429	247	17	112	504	82	483	5e-15	89.0
rs:WP_028505977	DNA topoisomerase I [Ruminococcus sp. FC2018].	25.87	433	261	17	107	505	76	482	5e-15	89.0
rs:WP_047265411	DNA topoisomerase I [Marinitoga sp. 1155].	24.96	617	344	25	7	591	9	538	5e-15	89.0
rs:WP_039980762	DNA topoisomerase I [Vibrio sagamiensis].	22.84	543	331	20	7	505	6	504	5e-15	89.0
rs:WP_021708677	DNA topoisomerase I [Vibrio azureus].	22.84	543	331	20	7	505	6	504	5e-15	89.0
rs:WP_039693966	DNA topoisomerase I [Dickeya solani].	24.60	439	283	15	88	505	89	500	5e-15	89.0
rs:WP_035002439	DNA topoisomerase I [Corynebacterium jeikeium].	24.64	560	323	24	7	505	10	531	5e-15	89.4
rs:XP_006601080	PREDICTED: DNA topoisomerase 3-alpha-like isoform X6 [Glycine max].	24.52	522	319	18	36	505	268	766	5e-15	89.0
rs:WP_026820190	DNA topoisomerase I [Arthrobacter castelli].	25.81	434	277	17	7	425	5	408	5e-15	89.0
rs:WP_012094926	DNA topoisomerase I [Bacillus cytotoxicus].	27.14	420	260	14	112	505	82	481	5e-15	89.0
rs:WP_007641057	topoisomerase I [Cellvibrio sp. BR].	22.99	461	321	12	59	505	69	509	5e-15	89.0
rs:WP_019899838	DNA topoisomerase I [Methylotenera mobilis].	25.85	530	318	20	7	504	5	491	5e-15	89.0
rs:WP_037555477	DNA topoisomerase I [Staphylococcus sp. URHA0057].	24.86	531	308	20	7	504	6	478	5e-15	89.0
rs:WP_002796370	DNA topoisomerase I [Microcystis aeruginosa].	24.73	550	319	20	5	505	3	506	5e-15	89.0
rs:WP_046661409	DNA topoisomerase I [Microcystis aeruginosa].	25.32	549	317	21	5	505	3	506	5e-15	89.0
rs:WP_015199327	DNA topoisomerase I [Calothrix parietina].	25.97	516	291	17	89	566	72	534	5e-15	89.0
tr:A0A0D0G883_LACBR	SubName: Full=Lactobacillus brevis strain TMW 1.313 Scaffold_1_TMW1313, whole genome shotgun sequence {ECO:0000313|EMBL:KIO95764.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIO95764.1};	26.87	387	228	16	147	505	3	362	5e-15	88.6
rs:WP_021713044	DNA topoisomerase I [Vibrio ezurae].	22.98	544	328	19	7	505	6	503	5e-15	89.0
rs:WP_021843600	DNA topoisomerase [Bacteroides sp. CAG:1060].	25.24	523	301	18	7	504	6	463	5e-15	89.0
rs:WP_012769871	MULTISPECIES: topoisomerase I [Dickeya].	25.75	431	267	18	99	505	99	500	5e-15	89.0
rs:WP_015144218	DNA topoisomerase I [Pleurocapsa minor].	25.00	548	318	20	5	504	3	505	5e-15	89.0
rs:WP_013366501	topoisomerase I [Enterobacter lignolyticus].	24.35	542	318	23	7	505	6	498	5e-15	89.0
rs:WP_039425546	DNA topoisomerase I [Porphyromonas gulae].	23.22	534	301	20	7	504	5	465	5e-15	89.0
rs:WP_034971914	DNA topoisomerase I [Corynebacterium jeikeium].	24.64	560	323	24	7	505	10	531	5e-15	89.4
rs:WP_041266580	DNA topoisomerase I, partial [Gemmatimonas aurantiaca].	23.71	544	320	23	7	505	85	578	5e-15	89.0
rs:WP_040966852	DNA topoisomerase I [Corynebacterium glutamicum].	24.89	474	281	18	86	505	83	535	5e-15	89.4
rs:WP_014451788	DNA topoisomerase I [Fervidobacterium pennivorans].	25.62	601	331	26	7	583	39	547	5e-15	89.0
rs:WP_021373390	DNA topoisomerase I [Peptoclostridium difficile].	26.42	530	306	25	5	504	4	479	5e-15	89.0
tr:C2WAW0_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.01	419	266	13	112	505	52	451	5e-15	88.6
rs:WP_046672863	DNA topoisomerase I [Sphingobacterium sp. Ag1].	25.11	442	275	12	89	504	59	470	5e-15	89.0
tr:S4TLK9_9CHLA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.09	537	330	19	7	504	6	498	5e-15	89.0
rs:WP_020267267	hypothetical protein [Aigarchaeota archaeon JGI 0000001-H6].	22.66	631	389	23	5	606	4	564	5e-15	88.6
rs:WP_018775034	MULTISPECIES: DNA topoisomerase I [Arthrobacter].	24.46	556	318	21	7	505	12	522	5e-15	89.0
gpu:AP013044_1404	DNA topoisomerase I [Tannerella forsythia 3313]	24.90	526	304	18	7	504	6	468	5e-15	89.0
rs:WP_021387786	DNA topoisomerase I [Peptoclostridium difficile].	26.59	534	300	25	5	504	4	479	5e-15	88.6
rs:WP_003640563	DNA topoisomerase I [Lactobacillus plantarum].	26.24	526	307	22	7	505	34	505	5e-15	89.0
rs:WP_012063858	DNA topoisomerase I [Alkaliphilus metalliredigens].	22.54	599	368	19	7	579	6	534	5e-15	88.6
tr:T0N6P8_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.44	266	169	8	309	554	9	270	5e-15	87.8
rs:WP_005370813	topoisomerase I [Photobacterium angustum].	24.12	539	328	19	7	505	6	503	5e-15	89.0
rs:WP_002791753	DNA topoisomerase I [Microcystis aeruginosa].	25.72	556	306	24	5	505	3	506	5e-15	89.0
rs:WP_002788527	DNA topoisomerase I [Microcystis aeruginosa].	24.73	550	319	20	5	505	3	506	5e-15	89.0
rs:WP_015328611	DNA topoisomerase I [Gloeocapsa sp. PCC 7428].	23.19	457	304	15	91	519	65	502	5e-15	88.6
rs:WP_042867454	DNA topoisomerase I [Aeromonas piscicola].	22.30	538	337	16	7	505	6	501	5e-15	89.0
rs:WP_013291224	DNA topoisomerase I [Caldicellulosiruptor obsidiansis].	23.12	571	344	19	7	553	5	504	5e-15	88.6
rs:WP_039427755	DNA topoisomerase I [Porphyromonas sp. COT-052 OH4946].	24.10	527	304	21	7	504	5	464	5e-15	89.0
rs:WP_032496840	DNA topoisomerase I, partial [Hydrogenivirga sp. 128-5-R1-1].	22.62	557	353	16	7	552	6	495	5e-15	88.2
rs:WP_038819896	hypothetical protein, partial [Pseudomonas savastanoi].	25.62	441	269	15	93	504	61	471	5e-15	88.6
rs:WP_045082622	MULTISPECIES: DNA topoisomerase I [Photobacterium].	24.12	539	328	19	7	505	6	503	5e-15	89.0
rs:WP_045149582	DNA topoisomerase I [Photobacterium angustum].	24.12	539	328	19	7	505	6	503	5e-15	89.0
rs:WP_010673895	MULTISPECIES: topoisomerase I [Aeromonas].	22.41	540	334	18	7	505	6	501	5e-15	89.0
rs:WP_043012384	DNA topoisomerase I [Corynebacterium jeikeium].	24.64	560	323	24	7	505	10	531	5e-15	89.0
rs:WP_034980045	DNA topoisomerase I [Corynebacterium jeikeium].	24.64	560	323	24	7	505	10	531	5e-15	89.0
rs:WP_034968817	DNA topoisomerase I [Corynebacterium jeikeium].	24.64	560	323	24	7	505	10	531	5e-15	89.0
rs:WP_016837424	DNA topoisomerase I [Ureibacillus thermosphaericus].	25.77	423	261	15	112	504	82	481	5e-15	88.6
rs:WP_038960642	DNA topoisomerase I [Atribacteria bacterium SCGC AB-164-A22].	22.86	525	333	17	7	505	6	484	5e-15	88.6
rs:WP_027326478	DNA topoisomerase I [Bacteroides pyogenes].	24.91	530	300	21	7	504	6	469	5e-15	89.0
rs:WP_035007783	DNA topoisomerase I [Corynebacterium jeikeium].	24.64	560	323	24	7	505	10	531	5e-15	89.0
rs:WP_012236045	ATP-dependent DNA helicase RecQ [Sorangium cellulosum].	30.04	223	138	6	4	224	1	207	5e-15	89.4
rs:WP_012236045	ATP-dependent DNA helicase RecQ [Sorangium cellulosum].	26.52	313	170	9	287	546	323	628	3e-13	83.6
rs:WP_005921909	DNA topoisomerase I [Xanthomonas axonopodis].	23.51	587	345	21	7	563	6	518	5e-15	89.0
rs:WP_038154321	DNA topoisomerase I [Trabulsiella guamensis].	24.30	535	327	20	7	505	6	498	5e-15	89.0
rs:WP_027123483	DNA topoisomerase I [Mycoplasma molare].	23.45	533	335	18	7	517	5	486	5e-15	88.6
rs:WP_026182515	DNA topoisomerase I [Leeia oryzae].	26.53	475	283	18	80	510	48	500	5e-15	89.0
rs:WP_038871634	DNA topoisomerase I [Cronobacter dublinensis].	23.64	533	333	18	7	505	6	498	5e-15	89.0
tr:G5IUV3_9ENTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.95	526	321	18	7	504	15	489	5e-15	88.6
rs:WP_043994823	DNA topoisomerase I [Moritella sp. PE36].	23.29	554	320	22	7	505	6	509	5e-15	89.0
rs:WP_025317066	DNA topoisomerase I [Spiroplasma mirum].	24.77	545	323	22	5	517	4	493	5e-15	88.6
rs:WP_037209660	DNA topoisomerase I [Rhodovulum sp. NI22].	25.05	539	310	23	4	505	1	482	5e-15	89.0
gp:CP002222_1474	DNA topoisomerase I [Lactobacillus plantarum subsp. plantarum ST-III]	25.81	523	311	21	7	504	2	472	5e-15	88.6
tr:C1ABE5_GEMAT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.71	544	320	23	7	505	53	546	5e-15	89.0
tr:K8AMF9_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.64	533	333	18	7	505	20	512	5e-15	89.0
tr:C2MPG2_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.89	421	264	15	112	505	75	474	5e-15	88.6
rs:WP_021696001	DNA topoisomerase I [Brevundimonas abyssalis].	25.15	485	279	18	80	510	46	500	5e-15	89.0
rs:WP_002305038	type I topoisomerase, partial [Enterococcus faecium].	31.34	201	124	4	376	563	26	225	6e-15	87.0
tr:A0A097XI93_9BURK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.02	487	317	15	43	504	25	483	6e-15	89.0
rs:WP_026985710	DNA topoisomerase I [Flavobacterium sp. URHB0058].	25.57	528	293	24	7	504	6	463	6e-15	89.0
rs:WP_027118545	DNA topoisomerase I [Lachnospiraceae bacterium YSB2008].	23.56	522	316	18	7	505	6	467	6e-15	88.6
rs:WP_027448276	DNA topoisomerase I [Pontibacillus marinus].	26.18	424	260	14	112	505	82	482	6e-15	88.6
rs:WP_001235857	hypothetical protein, partial [Salmonella enterica].	25.00	268	184	7	8	267	5	263	6e-15	85.5
rs:WP_001286972	DNA topoisomerase I [Bacillus cereus].	25.89	421	264	15	112	505	82	481	6e-15	88.6
rs:WP_004007690	DNA topoisomerase I [Mobiluncus curtisii].	23.56	573	314	21	7	505	9	531	6e-15	89.0
rs:WP_042889025	DNA topoisomerase, partial [Enterococcus faecalis].	28.15	238	159	7	315	544	1	234	6e-15	86.3
rs:WP_020431209	hypothetical protein, partial [Paenibacillus riograndensis].	26.69	326	203	10	285	580	2	321	6e-15	88.2
rs:WP_045915569	DNA topoisomerase I [Orientia tsutsugamushi].	24.86	527	321	21	7	504	4	484	6e-15	89.0
rs:WP_043983542	DNA topoisomerase I [Streptococcus equi].	23.36	518	327	18	7	504	30	497	6e-15	88.6
rs:WP_039439117	DNA topoisomerase I [Porphyromonas gulae].	23.74	535	299	21	7	505	5	466	6e-15	89.0
rs:WP_047220985	DNA topoisomerase I [Orientia tsutsugamushi].	24.86	527	321	21	7	504	4	484	6e-15	89.0
rs:WP_042648448	DNA topoisomerase I [Aeromonas media].	22.30	538	337	16	7	505	6	501	6e-15	89.0
rs:WP_016874429	DNA topoisomerase I [Chlorogloeopsis fritschii].	24.04	495	313	16	91	561	66	521	6e-15	88.6
rs:WP_013275886	DNA topoisomerase I [Thermosediminibacter oceani].	24.06	532	315	22	7	504	6	482	6e-15	88.6
rs:WP_037310690	DNA topoisomerase I [Ruegeria halocynthiae].	24.13	576	313	25	4	510	1	521	6e-15	89.0
rs:WP_040378997	DNA topoisomerase I, partial [Dethiobacter alkaliphilus].	25.31	565	323	22	7	544	6	498	6e-15	88.6
rs:WP_012959400	DNA topoisomerase I [Bacillus pseudofirmus].	23.85	524	324	18	7	504	6	480	6e-15	88.6
rs:WP_040506588	DNA topoisomerase I [Leptospira wolbachii].	23.86	528	310	21	18	504	1	477	6e-15	88.6
rs:WP_042988647	MULTISPECIES: hypothetical protein [Vibrio].	23.66	558	336	22	63	581	19	525	6e-15	88.6
rs:WP_008876148	DNA topoisomerase 1 [Mesorhizobium metallidurans].	25.14	549	307	24	4	505	1	492	6e-15	89.0
rs:WP_029645005	MULTISPECIES: DNA topoisomerase, partial [Lactobacillales].	28.15	238	159	7	315	544	1	234	6e-15	86.7
rs:WP_036181603	DNA topoisomerase I [Lysinibacillus manganicus].	26.01	419	265	12	112	504	82	481	6e-15	88.6
rs:WP_043623982	DNA topoisomerase I [Chromobacterium piscinae].	25.09	546	315	23	7	510	6	499	6e-15	88.6
rs:WP_045279509	DNA topoisomerase I [Microbacterium oxydans].	22.75	545	335	18	7	505	8	512	6e-15	89.0
tr:C2S7N1_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.89	421	264	15	112	505	52	451	6e-15	88.6
rs:WP_043298255	DNA topoisomerase I, partial [Burkholderia sp. TSV202].	24.02	487	317	15	43	504	25	483	6e-15	88.6
rs:WP_026063875	DNA topoisomerase I [Lactococcus garvieae].	25.52	529	302	22	7	504	35	502	6e-15	88.6
rs:WP_007137737	DNA topoisomerase I [Flavobacterium frigoris].	25.14	525	299	23	7	504	6	463	6e-15	89.0
tr:A0A061Q1G5_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.19	539	334	18	7	505	6	504	6e-15	89.0
rs:WP_004458499	DNA topoisomerase I [Clostridium perfringens].	24.38	525	320	20	7	505	6	479	6e-15	88.6
rs:WP_047258839	DNA topoisomerase I [Corynebacterium uterequi].	24.95	465	287	18	86	505	76	523	6e-15	89.0
rs:WP_022081022	DNA topoisomerase [Ruminococcus sp. CAG:488].	25.37	544	300	25	7	505	5	487	6e-15	88.6
rs:WP_003607894	DNA topoisomerase I [Weissella confusa].	24.01	529	317	19	7	505	30	503	6e-15	88.6
rs:WP_031939868	DNA topoisomerase I [Rhodococcus defluvii].	24.53	587	346	21	7	550	19	551	6e-15	89.0
rs:WP_009641356	DNA topoisomerase I [Capnocytophaga sp. CM59].	22.22	513	329	14	7	504	6	463	6e-15	89.0
tr:A0A090P938_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAK86565.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAK86565.1};	27.66	235	151	7	7	234	5	227	6e-15	85.5
rs:WP_036656511	DNA topoisomerase I [Paenibacillus wynnii].	24.43	528	317	21	7	504	6	481	6e-15	88.6
rs:WP_039434731	DNA topoisomerase I [Porphyromonas gulae].	24.10	527	304	21	7	504	5	464	6e-15	88.6
rs:WP_038883495	DNA topoisomerase I [Cronobacter dublinensis].	23.64	533	333	18	7	505	6	498	6e-15	89.0
rs:WP_011945076	DNA topoisomerase I [Orientia tsutsugamushi].	24.86	527	321	21	7	504	4	484	6e-15	88.6
rs:WP_034993148	DNA topoisomerase I [Corynebacterium jeikeium].	24.64	560	323	24	7	505	10	531	6e-15	89.0
tr:G6BMM8_PEPDI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.78	534	299	25	5	504	10	485	6e-15	88.6
rs:WP_035023683	DNA topoisomerase, partial [Enterococcus villorum].	28.05	246	165	7	307	544	78	319	6e-15	87.4
rs:WP_026701049	DNA topoisomerase I [Bacillus aidingensis].	24.58	419	272	12	112	505	83	482	6e-15	88.6
rs:WP_036795343	DNA topoisomerase I [Photobacterium phosphoreum].	24.89	458	295	17	69	505	74	503	6e-15	89.0
rs:WP_001286951	DNA topoisomerase I [Bacillus cereus].	26.01	419	266	13	112	505	82	481	6e-15	88.6
rs:WP_045638320	DNA topoisomerase I, partial [Peptococcaceae bacterium BRH_c4a].	23.22	603	367	21	5	579	9	543	6e-15	88.6
rs:WP_024859995	DNA topoisomerase I [Ruminococcus flavefaciens].	25.71	529	311	21	7	505	5	481	6e-15	88.6
rs:WP_009082009	DNA topoisomerase I [Peptostreptococcaceae bacterium AS15].	24.35	538	321	22	7	512	5	488	6e-15	88.6
tr:K8A3X1_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.83	533	332	18	7	505	20	512	6e-15	89.0
tr:C2ZBM2_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.30	419	269	14	112	505	75	474	6e-15	88.6
tr:C3C6F6_BACTU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.89	421	264	15	112	505	75	474	6e-15	88.6
rs:WP_043029703	DNA topoisomerase I [Streptococcus equi].	23.31	519	326	18	7	504	30	497	6e-15	88.6
rs:WP_046826724	DNA topoisomerase I [Afipia sp. LC387].	24.54	538	318	21	7	505	4	492	6e-15	89.0
rs:WP_039129857	DNA topoisomerase I [Leisingera sp. ANG-Vp].	24.78	565	315	24	4	510	1	513	6e-15	89.0
tr:G8BAX5_CANPC	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:CCE42199.1};	24.69	644	376	29	7	595	3	592	6e-15	88.2
tr:U2CMC3_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.72	530	301	20	7	504	21	484	6e-15	88.6
rs:XP_006601079	PREDICTED: DNA topoisomerase 3-alpha-like isoform X5 [Glycine max].	24.46	511	311	18	47	505	279	766	6e-15	89.0
rs:WP_043040559	DNA topoisomerase I [Streptococcus equi].	23.36	518	327	18	7	504	30	497	6e-15	88.6
rs:WP_027182567	DNA topoisomerase I [Desulfovibrio alaskensis].	24.43	528	315	20	7	505	6	478	6e-15	88.6
tr:C0GIT5_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.31	565	323	22	7	544	6	498	6e-15	88.6
rs:WP_042670629	DNA topoisomerase I [Streptococcus equi].	23.42	521	323	18	7	504	30	497	6e-15	88.6
rs:WP_045912339	DNA topoisomerase I [Orientia tsutsugamushi].	24.86	527	321	21	7	504	4	484	6e-15	88.6
rs:WP_009603463	topoisomerase I [Vibrio caribbeanicus].	24.40	455	301	14	69	505	74	503	6e-15	88.6
tr:X8K7D9_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.23	530	304	22	5	505	21	492	6e-15	88.6
rs:WP_001286973	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	25.89	421	264	15	112	505	82	481	6e-15	88.6
rs:WP_032984924	DNA topoisomerase I [Cronobacter condimenti].	23.83	533	332	18	7	505	6	498	6e-15	88.6
rs:WP_012441352	topoisomerase I [Erwinia tasmaniensis].	24.62	459	296	16	69	505	68	498	6e-15	88.6
rs:WP_002800297	DNA topoisomerase I [Microcystis aeruginosa].	24.73	550	319	20	5	505	3	506	6e-15	88.6
rs:WP_037586178	DNA topoisomerase I [Stenoxybacter acetivorans].	26.34	429	270	15	107	505	77	489	6e-15	88.6
rs:WP_021291589	MULTISPECIES: DNA topoisomerase I [Virgibacillus].	25.42	421	267	14	112	505	82	482	6e-15	88.6
tr:R2S4C9_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.05	246	165	7	307	544	83	324	6e-15	87.4
rs:WP_015741453	topoisomerase I [Cronobacter turicensis].	23.31	532	336	18	7	505	6	498	6e-15	88.6
rs:WP_038658773	DNA topoisomerase I [Cedecea neteri].	24.60	439	283	15	88	505	89	500	6e-15	88.6
rs:WP_047131249	DNA topoisomerase I [Staphylococcus condimenti].	23.91	527	318	18	7	504	6	478	6e-15	88.6
tr:A0A0D6PF16_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN79454.1};	26.17	554	303	25	7	510	13	510	6e-15	88.6
rs:WP_033502019	DNA topoisomerase III, partial [Bifidobacterium kashiwanohense].	27.52	258	160	7	307	539	11	266	6e-15	87.4
rs:WP_045825790	DNA topoisomerase I [Teredinibacter sp. 991H.S.0a.06].	22.89	533	349	17	7	505	6	510	6e-15	88.6
rs:WP_031431468	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	37.59	133	75	4	279	406	61	190	6e-15	84.3
rs:WP_014255154	DNA topoisomerase I [[Clostridium] clariflavum].	23.87	620	363	22	7	595	6	547	6e-15	88.6
rs:WP_042784671	DNA topoisomerase I [Serratia sp. SCBI].	25.78	446	269	17	88	505	87	498	7e-15	88.6
rs:WP_013816449	DNA topoisomerase I [Porphyromonas gingivalis].	23.78	534	298	21	7	504	5	465	7e-15	88.6
rs:WP_029447781	MULTISPECIES: DNA topoisomerase I [Cellulophaga].	24.58	533	294	22	7	504	6	465	7e-15	88.6
rs:WP_039972512	DNA topoisomerase I [Bacteroides pyogenes].	24.72	530	301	20	7	504	6	469	7e-15	88.6
rs:WP_002695179	DNA topoisomerase I [Treponema phagedenis].	22.55	603	368	22	7	582	18	548	7e-15	88.6
rs:WP_017437098	DNA topoisomerase I [Geobacillus caldoxylosilyticus].	24.62	520	317	21	112	598	82	559	7e-15	88.6
rs:WP_020026414	hypothetical protein [gamma proteobacterium SCGC AAA076-D13].	25.81	527	306	22	7	510	6	470	7e-15	88.6
rs:WP_023025047	MULTISPECIES: DNA topoisomerase I [Corynebacterium].	24.90	522	308	23	40	505	30	523	7e-15	89.0
rs:WP_040486728	DNA topoisomerase I, partial [Idiomarina sp. A28L].	24.13	460	297	16	69	505	74	504	7e-15	88.6
rs:WP_018658789	hypothetical protein [Allofustis seminis].	23.31	519	325	17	7	504	7	473	7e-15	88.6
rs:WP_045171440	DNA topoisomerase I [Ehrlichia mineirensis].	25.56	536	316	21	4	504	1	488	7e-15	88.6
tr:D1C7I9_SPHTD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.68	547	314	22	5	504	61	556	7e-15	88.6
tr:V5TZ61_CROSK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.31	532	336	18	7	505	20	512	7e-15	88.6
rs:WP_024478965	DNA topoisomerase I [Cellulophaga baltica].	24.58	533	294	22	7	504	6	465	7e-15	88.6
rs:WP_027130929	DNA topoisomerase I [Gemella cuniculi].	25.06	431	275	16	99	504	70	477	7e-15	88.6
rs:WP_029689028	DNA topoisomerase I [Thermoanaerobacter sp. A7A].	23.86	570	341	20	7	553	6	505	7e-15	88.6
rs:WP_043765344	DNA topoisomerase I [Roseivivax isoporae].	25.32	470	277	20	4	452	1	417	7e-15	88.6
rs:WP_042859807	DNA topoisomerase I [Dickeya sp. NCPPB 3274].	24.60	439	283	15	88	505	89	500	7e-15	88.6
rs:WP_018966009	DNA topoisomerase I [Porphyromonas gulae].	24.10	527	304	21	7	504	5	464	7e-15	88.6
rs:WP_004008771	DNA topoisomerase I [Mobiluncus curtisii].	23.56	573	314	21	7	505	9	531	7e-15	88.6
rs:WP_037490985	DNA topoisomerase I [Snodgrassella alvi].	25.56	540	305	23	7	505	6	489	7e-15	88.6
rs:WP_011609067	topoisomerase I [Histophilus somni].	24.50	449	271	15	88	505	93	504	7e-15	88.6
rs:WP_025701826	DNA topoisomerase I [Paenibacillus forsythiae].	24.34	530	315	23	7	504	6	481	7e-15	88.6
rs:WP_028277717	DNA topoisomerase I [Arthrobacter sp. I3].	24.46	556	318	21	7	505	12	522	7e-15	88.6
rs:WP_003043663	DNA topoisomerase I subunit omega [Sphingopyxis sp. MC1].	24.71	522	320	19	7	505	4	475	7e-15	88.6
rs:XP_006601078	PREDICTED: DNA topoisomerase 3-alpha-like isoform X4 [Glycine max].	24.57	521	318	18	36	504	266	763	7e-15	89.0
rs:WP_045417635	DNA topoisomerase I [Vibrio campbellii].	22.82	539	336	18	7	505	6	504	7e-15	88.6
rs:WP_018210926	DNA topoisomerase I [Desulfitobacterium hafniense].	25.26	574	333	23	5	553	4	506	7e-15	88.2
rs:WP_007079454	DNA topoisomerase I [Aeromicrobium marinum].	23.45	550	333	17	5	505	3	513	7e-15	88.6
rs:WP_032805444	DNA topoisomerase I [Cronobacter universalis].	23.31	532	336	18	7	505	6	498	7e-15	88.6
rs:WP_005875040	DNA topoisomerase I [Porphyromonas gingivalis].	23.74	535	299	21	7	505	5	466	7e-15	88.6
tr:K8DBD0_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.31	532	336	18	7	505	20	512	7e-15	88.6
rs:WP_046833762	hypothetical protein [Xanthomonas axonopodis].	28.48	165	106	5	301	456	8	169	7e-15	84.0
rs:WP_034800380	DNA topoisomerase I [Intrasporangium oryzae].	23.41	551	335	19	7	505	10	525	7e-15	88.6
rs:WP_015871044	topoisomerase I [Edwardsiella ictaluri].	25.11	438	282	17	88	505	87	498	7e-15	88.6
rs:WP_033568758	DNA topoisomerase I [Dickeya sp. 2B12].	24.83	439	282	15	88	505	89	500	7e-15	88.6
rs:WP_009222712	DNA topoisomerase, partial [Peptoniphilus sp. oral taxon 386].	24.95	521	320	18	7	504	6	478	7e-15	87.8
rs:WP_035023093	DNA topoisomerase I [Carnobacterium sp. WN1374].	23.55	569	352	20	1	540	1	515	7e-15	88.2
rs:WP_026906107	DNA topoisomerase I [Paucisalibacillus globulus].	24.71	526	318	22	7	504	6	481	7e-15	88.2
rs:WP_022557734	MULTISPECIES: hypothetical protein [Xanthomonas].	28.48	165	106	5	301	456	8	169	7e-15	84.0
rs:WP_022302396	DNA topoisomerase III [Bacteroides faecis CAG:32].	21.43	560	363	18	4	536	1	510	7e-15	88.2
rs:WP_034086253	DNA topoisomerase I [Pseudomonas aeruginosa].	24.35	497	299	19	86	553	58	506	7e-15	88.2
rs:WP_046323449	DNA topoisomerase I [Bifidobacterium asteroides].	22.88	555	330	21	7	505	8	520	7e-15	88.6
rs:WP_002749183	DNA topoisomerase I [Microcystis aeruginosa].	24.73	550	319	20	5	505	3	506	7e-15	88.6
rs:WP_041334940	DNA topoisomerase I, partial [Roseiflexus sp. RS-1].	24.17	542	320	19	7	504	6	500	7e-15	88.6
rs:WP_017507300	DNA topoisomerase I [beta proteobacterium L13].	25.09	550	310	21	7	510	6	499	7e-15	88.6
rs:WP_022668783	DNA topoisomerase I [Desulfospira joergensenii].	26.03	461	287	17	93	517	63	505	7e-15	88.6
rs:WP_014346412	DNA topoisomerase [Pyrobaculum oguniense].	22.58	589	368	23	7	565	4	534	7e-15	88.2
rs:WP_037272240	DNA topoisomerase I [Roseovarius mucosus].	24.26	544	311	23	4	524	1	466	7e-15	88.6
rs:WP_024575122	MULTISPECIES: DNA topoisomerase I [Afipia].	24.86	543	310	24	7	505	4	492	7e-15	88.6
rs:WP_001286958	DNA topoisomerase I [Bacillus cereus].	25.65	421	265	15	112	505	82	481	7e-15	88.2
rs:WP_029883572	DNA topoisomerase I [Enterobacter sp. T1-1].	24.35	538	323	20	7	505	6	498	7e-15	88.6
rs:WP_002762074	DNA topoisomerase I [Microcystis aeruginosa].	24.73	550	319	20	5	505	3	506	7e-15	88.6
rs:WP_002442541	DNA topoisomerase I [Staphylococcus caprae].	24.67	527	314	19	7	504	6	478	7e-15	88.2
rs:WP_028300153	DNA topoisomerase I [Oceanospirillum beijerinckii].	23.25	542	336	17	7	505	6	510	7e-15	88.6
rs:WP_014970695	DNA topoisomerase I [Exiguobacterium antarcticum].	25.85	530	307	23	7	504	6	481	7e-15	88.2
rs:WP_017724285	DNA topoisomerase I [Staphylococcus xylosus].	25.76	524	311	19	7	504	6	477	7e-15	88.2
rs:WP_002173098	DNA topoisomerase I [Bacillus cereus].	25.78	419	267	14	112	505	82	481	7e-15	88.2
rs:WP_001286966	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	25.89	421	264	15	112	505	82	481	7e-15	88.2
tr:J6XYG5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.74	274	175	9	166	429	29	289	7e-15	85.5
rs:WP_027353472	DNA topoisomerase I [Desulfosarcina sp. BuS5].	25.64	550	314	23	7	516	6	500	7e-15	88.2
rs:WP_021139069	DNA topoisomerase I subunit omega [Aeromonas salmonicida].	22.30	538	337	16	7	505	6	501	7e-15	88.6
rs:WP_002355997	toprim domain protein, partial [Enterococcus faecium].	33.13	166	102	5	42	205	26	184	7e-15	84.0
rs:WP_025714303	DNA topoisomerase I [Klebsiella sp. 10982].	23.83	533	332	18	7	505	6	498	7e-15	88.6
rs:WP_006990851	DNA topoisomerase I [Glaciecola mesophila].	23.75	539	333	18	7	505	6	506	7e-15	88.6
rs:WP_019601517	topoisomerase I [Teredinibacter turnerae].	23.08	533	348	17	7	505	6	510	7e-15	88.6
rs:WP_010731590	DNA topoisomerase III, partial [Enterococcus faecalis].	28.05	246	165	7	307	544	82	323	7e-15	87.8
rs:WP_004839147	DNA topoisomerase I [Anaerococcus vaginalis].	23.72	624	377	27	7	603	6	557	7e-15	88.2
rs:WP_019189987	hypothetical protein [Clostridiales bacterium 9403326].	24.51	616	377	21	7	599	6	556	7e-15	88.2
tr:F7RUZ0_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.13	460	297	16	69	505	74	504	7e-15	88.6
tr:A8V019_9AQUI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.97	566	340	18	7	552	6	495	8e-15	88.2
rs:WP_028498669	DNA topoisomerase I [Microvirgula aerodenitrificans].	24.73	558	312	23	3	510	2	501	8e-15	88.2
rs:WP_021417477	DNA topoisomerase I, partial [Peptoclostridium difficile].	26.42	530	306	25	5	504	4	479	8e-15	88.2
rs:WP_001286970	DNA topoisomerase I [Bacillus cereus].	25.30	419	269	14	112	505	82	481	8e-15	88.2
rs:WP_035011673	DNA topoisomerase I [Corynebacterium jeikeium].	24.82	560	322	25	7	505	10	531	8e-15	88.6
tr:S2VZR6_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.91	467	293	16	86	505	80	526	8e-15	88.6
rs:WP_011274238	DNA topoisomerase I [Corynebacterium jeikeium].	24.82	560	322	25	7	505	10	531	8e-15	88.6
rs:WP_035308752	DNA topoisomerase I [Brevundimonas sp. EAKA].	24.96	565	296	24	7	510	4	501	8e-15	88.6
rs:WP_017085853	topoisomerase I [Vibrio splendidus].	22.78	540	334	19	7	505	6	503	8e-15	88.6
tr:K2F0M1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.48	541	321	19	7	505	4	493	8e-15	88.2
rs:WP_042471896	DNA topoisomerase I [Bacillus sp. FF3].	25.11	446	273	15	93	504	63	481	8e-15	88.2
rs:WP_005762130	topoisomerase I [Pasteurella dagmatis].	25.56	446	270	16	88	505	93	504	8e-15	88.6
rs:WP_006702673	DNA topoisomerase I [Granulicatella elegans].	24.38	525	317	20	7	504	7	478	8e-15	88.2
rs:WP_015900135	DNA topoisomerase I [Staphylococcus carnosus].	23.72	527	319	19	7	504	6	478	8e-15	88.2
rs:WP_002880888	DNA topoisomerase I [Mycoplasma alkalescens].	24.43	524	306	20	7	504	6	465	8e-15	88.2
rs:WP_012533245	topoisomerase I [Aliivibrio fischeri].	24.68	466	286	19	69	505	73	502	8e-15	88.6
rs:WP_039299944	DNA topoisomerase I [Pectobacterium betavasculorum].	25.45	440	278	16	88	505	88	499	8e-15	88.6
rs:WP_040694667	DNA topoisomerase I [Propionimicrobium lymphophilum].	22.91	467	293	16	86	505	72	518	8e-15	88.6
rs:WP_005292236	DNA topoisomerase I [Corynebacterium jeikeium].	24.82	560	322	25	7	505	10	531	8e-15	88.6
rs:WP_038919025	DNA topoisomerase I [Dickeya sp. MK7].	25.00	448	270	17	88	505	89	500	8e-15	88.6
rs:WP_022790860	DNA topoisomerase I [Weissella halotolerans].	23.95	522	326	18	7	505	28	501	8e-15	88.2
rs:WP_025613743	DNA topoisomerase I [Cellulophaga baltica].	24.44	532	296	21	7	504	6	465	8e-15	88.6
rs:WP_008595679	DNA topoisomerase I [Nitratireductor pacificus].	25.41	543	307	24	7	505	4	492	8e-15	88.6
rs:WP_010441666	DNA topoisomerase I [Ruegeria conchae].	24.56	574	309	24	4	510	1	517	8e-15	88.6
rs:WP_008261370	DNA topoisomerase I [Brevundimonas sp. BAL3].	24.96	565	296	24	7	510	4	501	8e-15	88.6
rs:WP_026724184	DNA topoisomerase I [Flavobacterium sasangense].	25.48	526	296	24	7	504	6	463	8e-15	88.6
rs:WP_008560543	DNA topoisomerase I [Ruegeria sp. R11].	25.00	568	310	28	4	510	1	513	8e-15	88.6
rs:WP_029656583	DNA topoisomerase, partial [Enterococcus faecalis].	28.05	246	165	7	307	544	78	319	8e-15	87.4
rs:WP_026903078	DNA topoisomerase I [Pedobacter glucosidilyticus].	24.40	459	278	17	80	505	48	470	8e-15	88.6
rs:WP_045782768	DNA topoisomerase I [Klebsiella michiganensis].	24.78	460	304	15	64	505	63	498	8e-15	88.6
rs:XP_006601076	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Glycine max].	24.57	521	318	18	36	504	268	765	8e-15	88.6
rs:WP_019039527	DNA topoisomerase I [Psychroflexus tropicus].	25.37	540	301	24	7	512	6	477	8e-15	88.6
rs:WP_046198501	DNA topoisomerase I [Bacillus sp. UMTAT18].	25.89	421	264	15	112	505	82	481	8e-15	88.2
rs:WP_033616825	MULTISPECIES: DNA topoisomerase, partial [Enterococcus].	28.05	246	165	7	307	544	78	319	8e-15	87.4
rs:WP_005418793	topoisomerase I [Aliivibrio fischeri].	24.68	466	286	19	69	505	73	502	8e-15	88.6
tr:A0A0B8PGN0_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM65461.1};	29.01	262	166	7	4	258	1	249	8e-15	84.7
rs:WP_013346029	topoisomerase I [Ferrimonas balearica].	23.59	551	322	22	7	505	6	509	8e-15	88.6
rs:WP_029936286	DNA topoisomerase I [Thiomicrospira pelophila].	24.81	524	307	22	7	505	5	466	8e-15	88.2
rs:WP_001286957	MULTISPECIES: DNA topoisomerase I [Bacillus cereus group].	25.65	421	265	16	112	505	82	481	8e-15	88.2
rs:WP_001286955	MULTISPECIES: DNA topoisomerase I [Bacillus].	25.65	421	265	16	112	505	82	481	8e-15	88.2
rs:WP_033615686	DNA topoisomerase, partial [Enterococcus faecium].	28.05	246	165	7	307	544	78	319	8e-15	87.4
tr:W4PGQ1_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.91	530	300	21	7	504	70	533	8e-15	88.2
tr:C3IN36_BACTU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.65	421	265	16	112	505	41	440	8e-15	88.2
rs:WP_008466614	topoisomerase I [Pseudoalteromonas sp. BSi20439].	21.93	538	345	15	7	505	6	507	8e-15	88.6
rs:WP_045913310	DNA topoisomerase I [Orientia tsutsugamushi].	24.86	527	321	21	7	504	4	484	8e-15	88.2
rs:WP_021663473	DNA topoisomerase I [Porphyromonas gingivalis].	23.74	535	299	21	7	505	5	466	8e-15	88.2
rs:WP_037236659	DNA topoisomerase I [Rhodomicrobium udaipurense].	27.59	464	280	20	80	505	46	491	8e-15	88.6
rs:WP_000131186	conjugal transfer protein TraB [Acinetobacter baumannii].	23.87	444	274	16	97	505	69	483	8e-15	88.2
rs:WP_045958545	DNA topoisomerase I [Xenorhabdus poinarii].	25.37	473	297	17	69	513	68	512	8e-15	88.2
rs:WP_032983347	MULTISPECIES: DNA topoisomerase I [Cronobacter].	23.31	532	336	18	7	505	6	498	8e-15	88.2
rs:WP_029147941	DNA topoisomerase I [Methylophilus sp. 5].	24.81	540	313	19	7	504	5	493	8e-15	88.2
rs:WP_040177470	DNA topoisomerase III, partial [Klebsiella pneumoniae].	27.61	268	172	7	7	266	4	257	8e-15	85.1
rs:WP_033615842	DNA topoisomerase, partial [Enterococcus faecium].	28.05	246	165	7	307	544	78	319	8e-15	87.4
rs:WP_005706314	topoisomerase I [Haemophilus parahaemolyticus].	25.79	442	277	17	86	505	92	504	8e-15	88.2
rs:WP_013780472	DNA topoisomerase I [Mahella australiensis].	24.78	577	328	23	7	553	6	506	8e-15	88.2
rs:WP_043138282	DNA topoisomerase I [Ponticoccus sp. UMTAT08].	24.20	566	336	23	4	530	1	512	8e-15	88.2
rs:WP_012457773	DNA topoisomerase I [Porphyromonas gingivalis].	23.67	528	306	21	7	504	5	465	8e-15	88.2
rs:WP_026654728	DNA topoisomerase I [Butyrivibrio sp. AE3003].	25.62	441	278	19	93	504	57	476	8e-15	88.2
rs:WP_045026640	DNA topoisomerase I [Photobacterium phosphoreum].	24.89	458	295	17	69	505	74	503	8e-15	88.2
rs:WP_009022464	topoisomerase I [gamma proteobacterium NOR5-3].	22.75	545	334	19	7	505	6	509	8e-15	88.2
rs:WP_014231327	MULTISPECIES: topoisomerase I [Vibrio].	24.51	457	298	17	69	505	74	503	9e-15	88.2
rs:WP_004736442	topoisomerase I [Vibrio splendidus].	22.78	540	334	19	7	505	6	503	9e-15	88.2
rs:WP_017095683	topoisomerase I [Vibrio splendidus].	22.78	540	334	19	7	505	6	503	9e-15	88.2
rs:WP_008828828	MULTISPECIES: DNA topoisomerase I [Sphingomonadaceae].	26.10	544	302	25	7	510	4	487	9e-15	88.2
tr:A6FH32_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.46	466	287	19	70	505	72	502	9e-15	88.2
rs:WP_021384059	DNA topoisomerase I [Peptoclostridium difficile].	26.13	532	305	24	5	504	4	479	9e-15	88.2
rs:WP_027273071	DNA topoisomerase I [Leminorella grimontii].	24.72	534	322	22	7	505	6	494	9e-15	88.2
rs:WP_013230514	DNA topoisomerase I [Amycolatopsis mediterranei].	23.59	551	332	18	7	505	23	536	9e-15	88.6
rs:WP_035008817	DNA topoisomerase I [Corynebacterium jeikeium].	24.82	560	322	25	7	505	10	531	9e-15	88.6
rs:WP_045046682	DNA topoisomerase I [Rouxiella chamberiensis].	25.23	436	284	14	88	505	87	498	9e-15	88.2
rs:WP_021999052	DNA topoisomerase [Acetobacter sp. CAG:977].	24.82	548	323	23	4	510	1	500	9e-15	88.2
rs:WP_000341351	DNA topoisomerase I, partial [Streptococcus agalactiae].	25.52	388	249	13	136	504	22	388	9e-15	87.8
rs:WP_046215351	DNA topoisomerase I [Paenibacillus wulumuqiensis].	23.53	527	325	18	7	505	6	482	9e-15	88.2
rs:WP_012679592	DNA topoisomerase I [Streptococcus equi].	23.03	521	325	18	7	504	30	497	9e-15	88.2
rs:WP_027726063	DNA topoisomerase I [Tuberibacillus calidus].	25.00	424	268	17	109	504	79	480	9e-15	88.2
rs:WP_016918982	DNA topoisomerase I [Methylocystis parvus].	25.00	556	314	25	4	510	1	502	9e-15	88.2
rs:WP_020285757	DNA topoisomerase I [Osedax symbiont Rs2].	21.74	552	348	18	7	512	6	519	9e-15	88.2
rs:WP_039040523	MULTISPECIES: DNA topoisomerase I [Aeromonas].	22.30	538	337	16	7	505	6	501	9e-15	88.2
tr:V8AUH0_9LACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.52	529	302	22	7	504	35	502	9e-15	88.2
rs:WP_043030795	DNA topoisomerase I [Streptococcus equi].	22.94	523	323	19	7	504	30	497	9e-15	88.2
rs:WP_010645814	topoisomerase I [Vibrio campbellii].	22.82	539	336	18	7	505	6	504	9e-15	88.2
rs:WP_010699175	DNA topoisomerase I [Treponema denticola].	25.19	528	309	23	7	504	24	495	9e-15	88.2
rs:WP_042563873	DNA topoisomerase I [Flavobacterium sp. MEB061].	25.99	531	287	27	7	504	6	463	9e-15	88.2
rs:WP_026468687	DNA topoisomerase I [Amycolatopsis balhimycina].	23.23	551	334	18	7	505	23	536	9e-15	88.2
rs:WP_026063933	DNA topoisomerase I [Lactococcus garvieae].	25.52	529	302	22	7	504	35	502	9e-15	88.2
tr:R4PZ44_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	571	332	19	7	555	6	496	9e-15	88.2
rs:WP_033829233	DNA topoisomerase I [Bacillus sp. KW-12].	23.81	525	323	19	7	504	6	480	9e-15	88.2
tr:M2TPP4_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.48	531	316	20	7	505	12	489	9e-15	88.2
tr:C3FP15_BACTB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.65	421	265	16	112	505	75	474	9e-15	87.8
rs:WP_024359426	MULTISPECIES: DNA topoisomerase I [Klebsiella].	24.30	535	327	19	7	505	6	498	9e-15	88.2
rs:WP_021411029	DNA topoisomerase I [Peptoclostridium difficile].	26.42	530	306	25	5	504	4	479	9e-15	87.8
rs:WP_027606776	DNA topoisomerase I [Pseudomonas sp. LAMO17WK12:I2].	24.48	531	328	19	41	539	3	492	9e-15	87.8
rs:WP_036860537	DNA topoisomerase I [Porticoccus hydrocarbonoclasticus].	24.26	441	282	14	88	505	97	508	9e-15	88.2
rs:WP_021662118	DNA topoisomerase I [Porphyromonas gingivalis].	23.78	534	298	21	7	504	5	465	9e-15	88.2
rs:WP_011528644	DNA topoisomerase I [Streptococcus pyogenes].	23.75	522	320	18	7	504	29	496	9e-15	88.2
rs:WP_002780028	DNA topoisomerase 1 [Microcystis aeruginosa].	24.73	550	319	20	5	505	3	506	9e-15	88.2
rs:WP_012044745	DNA topoisomerase I [Bradyrhizobium sp. BTAi1].	24.07	536	328	20	4	505	1	491	9e-15	88.2
rs:WP_038281608	DNA topoisomerase I [alpha proteobacterium JLT2015].	24.48	531	316	20	7	505	6	483	9e-15	88.2
rs:WP_016868952	hypothetical protein, partial [Fischerella muscicola].	24.16	447	286	16	89	504	64	488	9e-15	87.8
rs:WP_004011329	DNA topoisomerase I [Mobiluncus curtisii].	23.56	573	314	21	7	505	9	531	9e-15	88.2
rs:WP_011366282	DNA topoisomerase I [Desulfovibrio alaskensis].	24.43	528	315	20	7	505	6	478	9e-15	88.2
rs:WP_002682495	DNA topoisomerase I [Treponema denticola].	25.38	528	308	23	7	504	24	495	9e-15	88.2
rs:WP_042958068	DNA topoisomerase, partial [Enterococcus faecium].	27.64	275	176	9	165	429	19	280	9e-15	85.1
rs:WP_044169489	DNA topoisomerase I [Porphyromonas catoniae].	25.44	452	279	16	81	505	47	467	9e-15	88.2
rs:WP_028108824	DNA topoisomerase I [Ferrimonas futtsuensis].	22.43	544	336	17	7	505	6	508	9e-15	88.2
rs:WP_038593555	DNA topoisomerase I [Paenibacillus sp. FSL H7-0357].	24.48	531	313	21	7	504	6	481	9e-15	87.8
rs:WP_013464804	topoisomerase I [Pseudoalteromonas sp. SM9913].	21.93	538	345	15	7	505	6	507	9e-15	88.2
tr:A5UT75_ROSS1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.17	542	320	19	7	504	6	500	9e-15	88.2
rs:WP_038139440	hypothetical protein, partial [Thiomicrospira sp. Milos-T1].	23.28	537	339	18	40	565	22	496	9e-15	87.4
rs:WP_004587792	DNA topoisomerase I subunit omega [Pseudoalteromonas agarivorans].	22.41	540	340	16	7	505	6	507	9e-15	88.2
tr:K8D9X4_CROSK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.44	529	337	18	7	505	6	496	9e-15	88.2
rs:WP_021397791	DNA topoisomerase I [Peptoclostridium difficile].	26.42	530	306	25	5	504	4	479	9e-15	87.8
rs:WP_035073895	DNA topoisomerase I [Anditalea andensis].	23.22	521	319	16	7	505	6	467	9e-15	88.2
rs:WP_013629763	DNA topoisomerase I [Planctomyces brasiliensis].	23.56	539	336	17	7	505	12	514	9e-15	88.2
tr:T2N8B6_PORGN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.78	534	298	21	7	504	37	497	9e-15	88.2
rs:WP_012677973	DNA topoisomerase I [Streptococcus equi].	22.75	523	324	19	7	504	30	497	1e-14	87.8
rs:WP_039432234	DNA topoisomerase I [Porphyromonas gulae].	24.10	527	304	21	7	504	5	464	1e-14	88.2
rs:WP_029719788	DNA topoisomerase I [Saccharopolyspora rectivirgula].	24.68	551	324	23	7	505	31	542	1e-14	88.2
rs:WP_042024775	DNA topoisomerase I [Aeromonas enteropelogenes].	22.22	540	335	18	7	505	6	501	1e-14	88.2
rs:WP_011072651	topoisomerase I [Shewanella oneidensis].	23.48	541	333	18	7	505	6	507	1e-14	88.2
tr:C3I4V3_BACTU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.65	421	265	16	112	505	52	451	1e-14	87.8
rs:WP_013376622	DNA topoisomerase I [Stigmatella aurantiaca].	22.98	570	323	23	7	516	72	585	1e-14	88.2
rs:WP_038887553	DNA topoisomerase I [Cronobacter dublinensis].	23.64	533	333	18	7	505	6	498	1e-14	88.2
rs:WP_015052691	DNA topoisomerase [Methanolobus psychrophilus].	24.52	469	276	19	107	548	102	519	1e-14	88.2
rs:WP_023578429	DNA topoisomerase I [Flavobacterium limnosediminis].	24.57	525	302	23	7	504	6	463	1e-14	88.2
rs:WP_010264176	DNA topoisomerase I [Anaplasma marginale].	25.00	528	327	22	4	504	1	486	1e-14	88.2
rs:WP_005426314	topoisomerase I [Vibrio campbellii].	22.82	539	336	18	7	505	6	504	1e-14	88.2
rs:WP_002121782	DNA topoisomerase I [Bacillus cereus].	25.78	419	267	14	112	505	82	481	1e-14	87.8
rs:WP_023404807	DNA topoisomerase I [Vibrio halioticoli].	23.44	546	323	21	7	505	6	503	1e-14	88.2
tr:K8E4W8_CARML	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CCO11554.2}; EC=5.99.1.2 {ECO:0000313|EMBL:CCO11554.2};	29.07	227	129	7	7	224	5	208	1e-14	84.7
rs:WP_002689561	DNA topoisomerase I [Treponema denticola].	25.38	528	308	23	7	504	24	495	1e-14	87.8
tr:A0A0A2VZ73_BEABA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.78	460	304	15	64	505	63	498	1e-14	88.2
rs:WP_043898447	DNA topoisomerase I [Porphyromonas gingivalis].	23.78	534	298	21	7	504	5	465	1e-14	87.8
rs:WP_045978387	DNA topoisomerase I [Pseudoalteromonas ruthenica].	23.49	545	328	18	7	505	6	507	1e-14	88.2
rs:WP_024034037	topoisomerase I [Pseudoalteromonas sp. NW 4327].	22.41	540	340	16	7	505	6	507	1e-14	88.2
rs:WP_039108965	DNA topoisomerase I [Flavobacterium sp. AED].	28.73	442	226	23	7	430	6	376	1e-14	88.2
rs:WP_046492712	DNA topoisomerase I [Flavobacteriaceae bacterium ASP10-09a].	25.91	521	300	20	7	504	6	463	1e-14	88.2
sp:TOP1_BUCAP	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.52	469	298	17	88	544	81	505	1e-14	88.2
rs:WP_038863258	DNA topoisomerase I [Vibrio campbellii].	22.82	539	336	18	7	505	6	504	1e-14	88.2
rs:WP_016080527	MULTISPECIES: DNA topoisomerase 1 [Bacillus].	25.30	419	269	14	112	505	82	481	1e-14	87.8
rs:WP_021665548	DNA topoisomerase I [Porphyromonas gingivalis].	23.74	535	299	21	7	505	5	466	1e-14	87.8
tr:H6RHI0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.62	524	303	20	7	504	6	463	1e-14	88.2
rs:WP_029656423	DNA topoisomerase, partial [Enterococcus faecalis].	28.15	238	159	7	315	544	1	234	1e-14	86.7
rs:WP_003824719	DNA topoisomerase I [Eikenella corrodens].	25.69	545	300	22	7	505	6	491	1e-14	87.8
rs:WP_029345828	DNA topoisomerase I [Lactococcus garvieae].	25.57	524	308	22	7	504	35	502	1e-14	87.8
tr:B9KIC6_ANAMF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	528	327	22	4	504	2	487	1e-14	88.2
rs:WP_012127429	topoisomerase I [Vibrio campbellii].	22.82	539	336	18	7	505	6	504	1e-14	88.2
rs:WP_017104280	topoisomerase I [Vibrio tasmaniensis].	22.78	540	334	19	7	505	6	503	1e-14	88.2
rs:WP_017025175	topoisomerase I [Vibrio rumoiensis].	23.29	541	330	19	7	505	6	503	1e-14	88.2
rs:WP_028877668	DNA topoisomerase I [Teredinibacter turnerae].	23.08	533	348	17	7	505	6	510	1e-14	88.2
rs:WP_014024778	DNA topoisomerase I [Lactococcus garvieae].	25.52	529	302	22	7	504	35	502	1e-14	87.8
rs:WP_005276527	DNA topoisomerase I [Corynebacterium accolens].	24.90	522	308	23	40	505	30	523	1e-14	88.2
rs:WP_011858416	conjugal transfer protein TraB [Acinetobacter baumannii].	24.10	444	273	16	97	505	13	427	1e-14	87.8
rs:WP_000131184	conjugal transfer protein TraB [Acinetobacter baumannii].	24.10	444	273	16	97	505	69	483	1e-14	87.8
rs:WP_036156769	DNA topoisomerase I [Maribacter forsetii].	25.24	519	308	19	7	504	6	465	1e-14	88.2
rs:WP_010691646	DNA topoisomerase I [Fructobacillus fructosus].	24.85	491	294	22	7	459	6	459	1e-14	87.8
tr:A0A0C1P0E7_9PSEU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.77	553	323	22	7	505	21	534	1e-14	88.2
tr:B6AM76_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.92	556	319	23	5	512	51	550	1e-14	88.2
rs:WP_003438266	DNA topoisomerase I [Peptoclostridium difficile].	26.42	530	306	25	5	504	4	479	1e-14	87.8
rs:WP_029655836	MULTISPECIES: DNA topoisomerase, partial [Enterococcus].	28.15	238	159	7	315	544	1	234	1e-14	86.3
rs:WP_038889185	DNA topoisomerase I [Vibrio campbellii].	22.82	539	336	18	7	505	6	504	1e-14	88.2
rs:WP_034977859	DNA topoisomerase I [Corynebacterium jeikeium].	24.64	560	323	24	7	505	10	531	1e-14	88.2
rs:WP_034313673	DNA topoisomerase I [Bacillus simplex].	26.13	421	261	15	112	504	82	480	1e-14	87.8
rs:WP_042407113	DNA topoisomerase I [Geobacillus caldoxylosilyticus].	25.42	421	264	15	112	504	82	480	1e-14	87.8
rs:WP_035167132	DNA topoisomerase I [Lactobacillus curieae].	25.90	417	263	15	112	504	99	493	1e-14	87.8
rs:WP_024791993	DNA topoisomerase I [Lebetimonas sp. JS138].	25.43	519	316	19	7	505	6	473	1e-14	87.8
rs:WP_014010951	DNA topoisomerase I [Corynebacterium variabile].	24.26	573	325	24	7	510	14	546	1e-14	88.2
rs:WP_028083163	DNA topoisomerase I [Dolichospermum circinale].	25.55	454	282	13	89	505	72	506	1e-14	87.8
rs:WP_021398006	DNA topoisomerase I [Peptoclostridium difficile].	26.42	530	306	25	5	504	4	479	1e-14	87.8
rs:WP_035067581	DNA topoisomerase I [Desulfovibrio termitidis].	25.05	539	303	22	7	505	6	483	1e-14	87.8
rs:WP_018250099	hypothetical protein [Orenia marismortui].	24.42	520	325	20	7	505	12	484	1e-14	87.8
rs:WP_045109699	DNA topoisomerase I [Moritella viscosa].	23.29	554	320	22	7	505	6	509	1e-14	88.2
rs:WP_023016601	MULTISPECIES: DNA topoisomerase I [Corynebacterium].	24.90	522	308	23	40	505	30	523	1e-14	88.2
rs:WP_002678704	DNA topoisomerase I [Treponema denticola].	25.76	528	306	23	7	504	24	495	1e-14	87.8
rs:WP_023386700	DNA topoisomerase I [Anaplasma marginale].	25.00	528	327	22	4	504	1	486	1e-14	87.8
rs:WP_021359105	DNA topoisomerase I [Peptoclostridium difficile].	26.42	530	306	25	5	504	4	479	1e-14	87.8
rs:WP_007525380	DNA topoisomerase I [Desulfovibrio sp. A2].	25.14	537	306	21	7	505	6	484	1e-14	87.8
rs:WP_007270845	DNA topoisomerase I [Arthrobacter gangotriensis].	24.59	553	323	23	7	505	14	526	1e-14	88.2
rs:WP_022619737	DNA topoisomerase I [Peptoclostridium difficile].	26.42	530	306	25	5	504	4	479	1e-14	87.8
rs:WP_008938177	DNA topoisomerase I subunit omega [Marinobacter santoriniensis].	22.14	542	342	18	7	505	6	510	1e-14	87.8
rs:WP_013865799	DNA topoisomerase I [Microlunatus phosphovorus].	24.37	476	278	20	86	505	74	523	1e-14	88.2
rs:WP_039504052	hypothetical protein, partial [Prauserella sp. Am3].	24.77	553	323	22	7	505	21	534	1e-14	88.2
rs:WP_036876504	hypothetical protein, partial [Prauserella rugosa].	24.77	553	323	22	7	505	21	534	1e-14	88.2
rs:WP_012023927	DNA topoisomerase I [Flavobacterium johnsoniae].	26.04	530	288	25	7	504	6	463	1e-14	87.8
rs:WP_000131185	conjugal transfer protein TraB [Acinetobacter baumannii].	24.10	444	273	16	97	505	69	483	1e-14	87.8
rs:WP_036015111	DNA topoisomerase I [Bradyrhizobium yuanmingense].	23.84	537	328	20	4	505	1	491	1e-14	87.8
rs:WP_041081072	DNA topoisomerase I [Thermotoga profunda].	25.18	560	318	23	7	542	5	487	1e-14	87.8
rs:WP_009892959	DNA topoisomerase I [Peptoclostridium difficile].	26.42	530	306	25	5	504	4	479	1e-14	87.8
rs:WP_027009875	DNA topoisomerase I [Conchiformibius kuhniae].	25.98	435	267	13	107	505	77	492	1e-14	87.8
rs:WP_024614709	DNA topoisomerase I [Clostridium sp. Ade.TY].	25.34	521	319	20	7	505	6	478	1e-14	87.8
rs:WP_022490361	DNA topoisomerase [Clostridium sp. CAG:567].	23.58	615	346	23	7	580	6	537	1e-14	87.8
rs:WP_010559875	topoisomerase I [Pseudoalteromonas spongiae].	23.06	542	332	18	7	505	6	505	1e-14	87.8
rs:WP_005468581	DNA topoisomerase I [Porphyromonas catoniae].	25.44	452	279	16	81	505	47	467	1e-14	87.8
rs:WP_037997223	DNA topoisomerase I [Thermoactinomyces sp. Gus2-1].	26.33	433	255	18	107	504	77	480	1e-14	87.8
rs:WP_038862609	DNA topoisomerase I [Cronobacter muytjensii].	23.45	533	334	18	7	505	6	498	1e-14	87.8
rs:WP_027414585	DNA topoisomerase I [Aneurinibacillus terranovensis].	25.59	426	269	15	107	505	77	481	1e-14	87.8
rs:WP_001286956	DNA topoisomerase I [Bacillus thuringiensis].	25.65	421	265	16	112	505	82	481	1e-14	87.8
rs:WP_028550412	DNA topoisomerase I [Paenibacillus sp. UNC451MF].	24.29	531	318	21	5	504	4	481	1e-14	87.8
rs:WP_017999241	DNA topoisomerase I [Paracoccus sp. N5].	24.30	535	316	20	4	505	1	479	1e-14	87.8
rs:WP_029485677	DNA topoisomerase, partial [Enterococcus faecium].	27.64	246	166	6	307	544	64	305	1e-14	87.0
rs:WP_040980091	DNA topoisomerase I [Oceanobacillus sp. S5].	23.76	526	325	19	7	505	6	482	1e-14	87.8
rs:WP_041405792	DNA topoisomerase I [Shewanella denitrificans].	23.20	543	332	18	7	505	6	507	1e-14	87.8
rs:WP_015231277	DNA topoisomerase I [Deinococcus peraridilitoris].	23.28	537	337	22	5	506	3	499	1e-14	87.4
rs:WP_008778772	DNA topoisomerase III [Parabacteroides sp. 20_3].	21.80	555	360	22	4	534	1	505	1e-14	87.4
rs:WP_017411764	topoisomerase I [Aeromonas salmonicida].	22.30	538	337	16	7	505	6	501	1e-14	87.8
rs:WP_028135920	DNA topoisomerase I [Bradyrhizobium japonicum].	23.84	537	328	20	4	505	1	491	1e-14	87.8
rs:WP_039232154	DNA topoisomerase I [Bacillus thermotolerans].	25.59	426	264	15	112	505	82	486	1e-14	87.8
rs:WP_012148895	DNA topoisomerase I [Rickettsia canadensis].	24.73	546	321	23	7	510	4	501	1e-14	87.8
rs:WP_013188968	DNA topoisomerase I [Mobiluncus curtisii].	23.56	573	314	21	7	505	9	531	1e-14	87.8
tr:K8B7C3_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.12	532	337	18	7	505	20	512	1e-14	87.8
rs:WP_024495662	DNA topoisomerase I [Candidatus Schmidhempelia bombi].	26.17	447	286	17	79	505	77	499	1e-14	87.8
rs:WP_002817879	hypothetical protein, partial [Campylobacter coli].	23.81	252	180	6	8	257	5	246	1e-14	84.3
rs:WP_027276830	DNA topoisomerase I [Rhodopseudomonas palustris].	24.16	534	325	21	7	505	4	492	1e-14	87.8
rs:WP_027367012	DNA topoisomerase I [Desulfovibrio africanus].	24.35	538	317	19	7	505	6	492	1e-14	87.8
rs:WP_045967592	DNA topoisomerase I [Flavobacterium sp. 316].	24.38	525	303	21	7	504	6	463	1e-14	87.8
rs:WP_046401192	DNA topoisomerase I [Lactococcus garvieae].	25.57	524	308	22	7	504	35	502	1e-14	87.8
rs:WP_002507864	MULTISPECIES: DNA topoisomerase I [Staphylococcus].	25.05	527	312	21	7	504	6	478	1e-14	87.4
rs:WP_042467105	DNA topoisomerase I [Aeromonas salmonicida].	22.30	538	337	16	7	505	6	501	1e-14	87.8
tr:F9VDX9_LACGL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.52	529	302	22	7	504	56	523	1e-14	87.8
rs:WP_036884824	DNA topoisomerase I, partial [Prevotella disiens].	24.04	337	229	7	7	333	5	324	1e-14	85.1
rs:WP_029420516	DNA topoisomerase I [Alicyclobacillus macrosporangiidus].	24.20	529	318	21	7	504	6	482	1e-14	87.8
tr:Q31J81_THICR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.98	517	317	18	7	504	5	464	1e-14	87.8
tr:Q12LR8_SHEDO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.20	543	332	18	7	505	22	523	1e-14	87.8
rs:WP_014630190	DNA topoisomerase I [Thermus thermophilus].	24.40	545	313	25	5	505	17	506	1e-14	87.8
rs:WP_032807398	DNA topoisomerase I [Cronobacter turicensis].	23.12	532	337	18	7	505	6	498	1e-14	87.8
tr:S6VCH0_PSESF	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EPN65471.1}; Flags: Fragment;	30.98	184	116	3	94	273	2	178	1e-14	83.6
rs:WP_021377880	DNA topoisomerase I [Peptoclostridium difficile].	26.42	530	306	25	5	504	4	479	1e-14	87.4
tr:D6SQD4_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.39	518	338	16	7	505	13	485	1e-14	87.8
rs:WP_005470465	topoisomerase I [Vibrio sp. 16].	23.85	457	301	16	69	505	74	503	1e-14	87.8
rs:WP_010739369	DNA topoisomerase 1 [Enterococcus malodoratus].	24.15	530	315	19	7	504	7	481	1e-14	87.4
rs:WP_011320483	DNA topoisomerase I [Anabaena variabilis].	23.70	443	289	13	91	504	66	488	1e-14	87.4
rs:WP_046893610	DNA topoisomerase I [Morganella morganii].	25.37	540	312	22	7	505	6	495	1e-14	87.8
tr:A0A015SDB8_BACFG	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EXY68292.1};	26.64	274	188	7	278	544	47	314	1e-14	86.7
rs:WP_032946566	DNA topoisomerase I, partial [Bacteroides vulgatus].	23.57	471	294	15	88	536	3	429	1e-14	87.0
tr:K2E740_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.70	533	329	19	7	504	4	488	1e-14	87.4
rs:WP_015214496	DNA topoisomerase I [Anabaena cylindrica].	24.22	446	285	15	91	505	66	489	1e-14	87.4
rs:WP_040047345	DNA topoisomerase I [Bacillaceae bacterium MTCC 8252].	25.59	426	264	15	112	505	82	486	1e-14	87.4
rs:WP_010996787	DNA topoisomerase I [Nostoc sp. PCC 7120].	23.48	443	290	13	91	504	66	488	1e-14	87.4
rs:WP_007566173	DNA topoisomerase I [Methylobacterium sp. GXF4].	24.42	557	316	23	4	510	1	502	1e-14	87.8
rs:WP_012167784	DNA topoisomerase I [Acaryochloris marina].	24.63	479	293	17	91	544	65	500	1e-14	87.4
rs:WP_027701667	DNA topoisomerase I [[Clostridium] mangenotii].	25.57	528	309	22	7	504	6	479	1e-14	87.4
rs:WP_005942683	DNA topoisomerase III [Bacteroides massiliensis].	21.80	555	360	21	4	534	1	505	1e-14	87.4
rs:WP_040418491	DNA topoisomerase I [Desulfonatronospira thiodismutans].	22.39	518	338	16	7	505	6	478	1e-14	87.4
rs:WP_046522153	DNA topoisomerase I [Bacillus sp. SA2-6].	25.28	439	280	15	93	504	63	480	1e-14	87.4
rs:WP_005280920	DNA topoisomerase I [Corynebacterium accolens].	24.90	522	308	23	40	505	30	523	1e-14	87.8
rs:WP_017461890	DNA topoisomerase I [Dyella ginsengisoli].	25.09	546	311	19	7	505	6	500	1e-14	87.8
rs:WP_004141651	DNA topoisomerase I [Cardiobacterium hominis].	24.71	522	312	19	7	500	6	474	1e-14	87.8
rs:WP_027094806	DNA topoisomerase I [[Clostridium] viride].	22.63	539	328	19	1	505	1	484	1e-14	87.8
rs:WP_033711194	DNA topoisomerase I, partial [Bacillus cereus].	27.14	350	219	11	277	606	40	373	1e-14	87.0
rs:WP_019174490	DNA topoisomerase I [Brevibacterium massiliense].	24.49	592	331	19	7	544	1	530	1e-14	87.8
tr:K1ZI81_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.76	526	329	18	7	505	5	485	1e-14	87.4
rs:WP_026763856	DNA topoisomerase I [Sediminibacterium salmoneum].	25.11	438	281	15	89	505	59	470	1e-14	87.8
rs:WP_039478450	DNA topoisomerase I [Vibrio sinaloensis].	24.07	457	300	16	69	505	74	503	1e-14	87.8
rs:WP_019668894	DNA topoisomerase I [Eudoraea adriatica].	24.90	522	306	19	7	504	6	465	1e-14	87.8
rs:WP_015615734	DNA topoisomerase I [Clostridium pasteurianum].	25.18	552	314	23	7	517	6	499	1e-14	87.4
rs:WP_026555994	DNA topoisomerase I [Arthrobacter sp. 35W].	25.14	553	320	20	7	505	16	528	1e-14	87.8
tr:A0A0B8PSF8_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.54	169	99	5	254	418	35	192	1e-14	83.6
rs:WP_040488363	DNA topoisomerase I, partial [Fodinicurvata sediminis].	24.72	542	311	23	7	505	4	491	1e-14	87.8
rs:WP_038298915	DNA topoisomerase I, partial [actinobacterium acMicro-4].	25.89	564	310	23	2	505	3	518	1e-14	87.8
rs:WP_038212929	DNA topoisomerase I [Vibrio variabilis].	23.85	457	301	16	69	505	74	503	1e-14	87.8
rs:WP_038192898	DNA topoisomerase I [Vibrio sinaloensis].	23.85	457	301	16	69	505	74	503	1e-14	87.8
rs:WP_021422224	DNA topoisomerase I [Peptoclostridium difficile].	26.42	530	306	25	5	504	4	479	1e-14	87.4
rs:WP_009846346	topoisomerase I [Vibrio sp. MED222].	22.78	540	334	19	7	505	6	503	1e-14	87.8
rs:WP_037578240	DNA topoisomerase I [Streptococcus equi].	23.36	518	327	18	7	504	30	497	1e-14	87.4
rs:WP_020330226	DNA topoisomerase I [Vibrio fluvialis].	24.07	457	300	15	69	505	77	506	1e-14	87.8
rs:WP_008587919	DNA topoisomerase I [Salimicrobium sp. MJ3].	26.65	424	258	16	112	505	83	483	1e-14	87.4
tr:U4QTL0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.92	556	319	23	5	512	51	550	1e-14	87.8
rs:WP_038138899	DNA topoisomerase I [Vibrio caribbeanicus].	23.85	457	301	16	69	505	74	503	1e-14	87.8
rs:WP_013585761	DNA topoisomerase I [Microbacterium testaceum].	23.20	582	358	20	7	550	8	538	1e-14	87.8
rs:WP_028887838	DNA topoisomerase I [Tenacibaculum ovolyticum].	27.40	416	255	15	107	504	77	463	1e-14	87.8
rs:WP_002693373	DNA topoisomerase I [Treponema denticola].	25.38	528	308	23	7	504	24	495	1e-14	87.4
rs:XP_001771420	predicted protein, partial [Physcomitrella patens].	24.95	541	301	20	5	495	2	487	1e-14	87.0
rs:WP_043789136	DNA topoisomerase I [Amycolatopsis rifamycinica].	22.87	551	336	17	7	505	23	536	1e-14	87.8
rs:WP_034412968	DNA topoisomerase I [Candidatus Photodesmus blepharus].	24.86	531	338	18	3	504	2	500	1e-14	87.8
rs:WP_019935728	topoisomerase I [Oceanimonas smirnovii].	23.58	547	332	20	3	505	2	506	1e-14	87.8
rs:WP_028256007	DNA topoisomerase I [Veillonella magna].	24.29	527	319	22	5	504	60	533	1e-14	87.4
rs:WP_033521565	DNA topoisomerase I [Bifidobacterium bohemicum].	23.29	554	326	18	7	505	8	517	1e-14	87.8
tr:A0A078LGR5_CITKO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.11	535	328	19	7	505	6	498	1e-14	87.8
rs:WP_046420442	DNA topoisomerase, partial [Xylella fastidiosa].	25.64	273	183	5	8	270	5	267	1e-14	84.3
rs:WP_041651541	DNA topoisomerase I [Anaplasma centrale].	25.09	530	324	20	4	504	1	486	1e-14	87.4
rs:XP_010432895	PREDICTED: uncharacterized protein LOC104717073 [Camelina sativa].	27.20	522	296	24	47	510	503	998	1e-14	87.8
rs:WP_041153557	hypothetical protein [Lactobacillus plantarum].	25.95	316	199	11	306	603	4	302	1e-14	86.3
rs:WP_021812978	DNA topoisomerase I [Psychrobacter aquaticus].	24.54	436	291	14	88	505	104	519	1e-14	87.8
rs:WP_038904398	DNA topoisomerase I [Dickeya zeae].	25.97	439	277	17	88	505	95	506	1e-14	87.8
tr:A0A094RJF9_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.89	564	310	23	2	505	3	518	1e-14	87.8
rs:WP_011261684	DNA topoisomerase I [Aliivibrio fischeri].	24.68	466	286	19	69	505	73	502	1e-14	87.8
rs:WP_016897101	DNA topoisomerase I [Aerococcus viridans].	23.12	519	328	17	7	504	7	475	1e-14	87.4
rs:WP_015817498	topoisomerase I [Teredinibacter turnerae].	23.16	531	353	16	7	505	6	513	1e-14	87.8
rs:WP_000520441	topoisomerase I [Vibrio sp. RC586].	24.67	458	296	16	69	505	76	505	1e-14	87.8
rs:WP_021320765	DNA topoisomerase I [Streptococcus equi].	23.36	518	327	18	7	504	30	497	1e-14	87.4
rs:WP_034574126	DNA topoisomerase I [Mageeibacillus indolicus].	23.97	580	336	20	5	553	4	509	1e-14	87.4
rs:WP_028835835	MULTISPECIES: DNA topoisomerase I [Pseudoalteromonas].	21.93	538	345	15	7	505	6	507	1e-14	87.8
rs:WP_027573622	DNA topoisomerase I [Bradyrhizobium sp. WSM1743].	24.16	538	325	21	4	505	1	491	1e-14	87.8
rs:WP_031832854	DNA topoisomerase III, partial [Staphylococcus aureus].	28.11	217	138	6	7	221	5	205	1e-14	83.6
gp:AF088896_23	topoisomerase I [Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821]	24.81	528	316	21	7	505	9	484	1e-14	87.8
tr:A0A059N3S6_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.09	235	157	7	318	544	1	231	1e-14	85.1
rs:WP_005312182	topoisomerase I [Aeromonas salmonicida].	22.30	538	337	16	7	505	6	501	1e-14	87.4
rs:WP_004285786	DNA topoisomerase I [Neisseria weaveri].	26.15	436	262	17	107	505	77	489	1e-14	87.4
rs:WP_000520437	topoisomerase I [Vibrio mimicus].	24.45	458	297	16	69	505	76	505	1e-14	87.4
rs:WP_017089558	topoisomerase I [Vibrio splendidus].	22.59	540	335	19	7	505	6	503	1e-14	87.4
rs:WP_041089031	DNA topoisomerase I [Jeotgalibacillus soli Cunha et al. 2012].	24.94	421	269	14	112	505	82	482	1e-14	87.4
rs:WP_022357103	DNA topoisomerase [Ruminococcus sp. CAG:379].	23.68	587	348	22	7	568	5	516	1e-14	87.4
rs:WP_045255925	DNA topoisomerase I [Microbacterium hydrocarbonoxydans].	23.36	518	313	18	43	505	14	502	1e-14	87.8
tr:W8V6A2_YEREN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.92	436	279	16	88	504	93	503	1e-14	87.8
rs:WP_032080259	DNA topoisomerase I [Vibrio fluvialis].	24.07	457	300	15	69	505	77	506	1e-14	87.4
rs:WP_002358260	DNA topoisomerase, partial [Enterococcus faecium].	31.31	198	122	4	379	563	2	198	1e-14	84.7
rs:WP_012603610	topoisomerase I [Vibrio tasmaniensis].	22.78	540	334	19	7	505	6	503	1e-14	87.4
rs:WP_016899533	topoisomerase I [Pseudoalteromonas sp. PAMC 22718].	21.93	538	345	15	7	505	6	507	1e-14	87.4
rs:WP_046938354	DNA topoisomerase III, partial [Xanthomonas perforans].	31.07	177	114	4	8	184	5	173	1e-14	83.2
rs:WP_045801345	DNA topoisomerase I [Muricauda lutaonensis].	24.13	518	317	18	7	505	6	466	1e-14	87.4
rs:WP_016941328	topoisomerase I [Dickeya zeae].	25.97	439	277	17	88	505	95	506	1e-14	87.4
tr:A0A099SXT5_METMT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.52	575	345	25	5	548	3	519	1e-14	87.4
rs:WP_038674305	DNA topoisomerase I [Streptococcus equi].	23.36	518	327	18	7	504	30	497	1e-14	87.4
rs:WP_019124724	DNA topoisomerase I [Peptoniphilus grossensis].	23.90	523	325	19	7	504	6	480	1e-14	87.4
tr:D1AS91_ANACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.09	530	324	20	4	504	2	487	1e-14	87.4
rs:WP_018986690	DNA topoisomerase I [Methylophilus methylotrophus].	24.44	540	315	20	7	504	5	493	1e-14	87.4
rs:WP_046825087	DNA topoisomerase I [Tannerella forsythia].	24.71	526	305	18	7	504	6	468	1e-14	87.4
rs:WP_022364712	DNA topoisomerase [Clostridium sp. CAG:505].	25.43	527	310	20	7	504	24	496	1e-14	87.4
rs:WP_034335979	hypothetical protein, partial [Deinococcus misasensis].	25.70	463	281	15	107	544	89	513	1e-14	87.4
rs:WP_028509937	DNA topoisomerase I [Ruminococcus sp. NK3A76].	25.35	430	267	14	107	505	76	482	1e-14	87.4
rs:WP_044362274	DNA topoisomerase I [Vibrio fluvialis].	24.07	457	300	15	69	505	77	506	1e-14	87.4
rs:WP_020023671	hypothetical protein [gamma proteobacterium SCGC AAA076-D02].	25.81	527	306	22	7	510	6	470	2e-14	87.4
rs:WP_033102497	MULTISPECIES: DNA topoisomerase I [Alteromonadales].	21.93	538	345	15	7	505	6	507	2e-14	87.4
tr:K8D3D3_CROSK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.31	532	336	18	7	505	20	512	2e-14	87.4
rs:WP_012610322	DNA topoisomerase I [Desulfatibacillum alkenivorans].	24.63	467	286	17	88	515	58	497	2e-14	87.4
rs:WP_005988628	DNA topoisomerase I [Desulfovibrio africanus].	24.35	538	317	19	7	505	6	492	2e-14	87.4
rs:WP_005846717	MULTISPECIES: DNA topoisomerase III [Bacteroides].	21.57	612	404	23	4	590	1	561	2e-14	87.0
rs:WP_026689912	DNA topoisomerase I [Bacillus aurantiacus].	25.12	418	269	14	112	504	82	480	2e-14	87.4
rs:WP_008193600	DNA topoisomerase I [Labrenzia alexandrii].	24.70	579	298	29	4	512	1	511	2e-14	87.4
rs:WP_004424930	DNA topoisomerase I [Mycoplasma auris].	24.43	524	305	20	7	504	6	464	2e-14	87.0
tr:A0A098FAS6_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.13	421	261	15	112	504	82	480	2e-14	87.4
rs:WP_008379664	DNA topoisomerase I [Enterococcus sp. C1].	24.57	525	319	19	7	504	7	481	2e-14	87.4
rs:WP_023020431	MULTISPECIES: DNA topoisomerase I [Corynebacterium].	24.73	558	320	25	5	505	10	524	2e-14	87.8
rs:WP_027547207	DNA topoisomerase I [Bradyrhizobium sp. WSM2254].	23.55	535	332	19	4	505	1	491	2e-14	87.4
rs:WP_026696251	DNA topoisomerase I [Bacillus chagannorensis].	25.18	425	259	14	112	504	82	479	2e-14	87.4
rs:WP_042664349	hypothetical protein [Aigarchaeota archaeon SCGC AAA471-F17].	22.61	628	393	23	5	606	4	564	2e-14	87.0
rs:WP_008279117	DNA topoisomerase I [Roseovarius sp. TM1035].	24.95	465	273	20	4	447	1	410	2e-14	87.4
rs:WP_010389785	topoisomerase I [Pseudoalteromonas undina].	21.75	538	346	15	7	505	6	507	2e-14	87.4
rs:WP_021101011	DNA topoisomerase I [Litoreibacter arenae].	23.73	531	327	17	4	505	1	482	2e-14	87.4
rs:WP_012961161	DNA topoisomerase III [Bacillus pseudofirmus].	27.84	291	190	9	302	581	1	282	2e-14	85.9
rs:WP_022168066	DNA topoisomerase [Clostridium sp. CAG:221].	26.00	527	309	21	7	505	6	479	2e-14	87.4
rs:WP_004387669	topoisomerase I [Cronobacter sakazakii].	23.31	532	336	18	7	505	6	498	2e-14	87.4
rs:WP_028042355	DNA topoisomerase I [Candidatus Stoquefichus massiliensis].	24.30	498	316	17	107	584	80	536	2e-14	87.4
rs:WP_033799838	DNA topoisomerase I, partial [Bacillus pseudomycoides].	25.16	310	185	8	5	297	4	283	2e-14	84.3
rs:WP_038925913	DNA topoisomerase I [Dickeya zeae].	25.97	439	277	17	88	505	95	506	2e-14	87.4
rs:WP_037419529	DNA topoisomerase I [Shewanella xiamenensis].	23.48	541	333	18	7	505	6	507	2e-14	87.4
rs:WP_017051947	topoisomerase I [Vibrio genomosp. F6].	22.69	542	332	19	7	505	6	503	2e-14	87.4
rs:WP_027188295	DNA topoisomerase I [Desulfovibrio cuneatus].	25.05	519	320	19	7	504	6	476	2e-14	87.4
rs:WP_028316527	DNA topoisomerase I [Desulfatibacillum aliphaticivorans].	24.63	467	286	17	88	515	58	497	2e-14	87.4
rs:WP_046355048	DNA topoisomerase I [Pseudoalteromonas luteoviolacea].	22.65	543	335	16	7	505	6	507	2e-14	87.4
rs:WP_026574870	DNA topoisomerase I [Bacillus sp. UNC438CL73TsuS30].	25.06	423	264	15	112	504	82	481	2e-14	87.0
rs:WP_022702956	DNA topoisomerase I [Pseudorhodobacter ferrugineus].	25.75	501	295	21	4	480	1	448	2e-14	87.4
rs:WP_031897066	DNA topoisomerase III, partial [Staphylococcus aureus].	29.52	227	138	7	331	544	1	218	2e-14	84.7
rs:WP_003454290	DNA topoisomerase I [Pseudomonas pseudoalcaligenes].	24.64	487	309	19	43	505	32	484	2e-14	87.0
rs:WP_035125554	DNA topoisomerase I [Flavobacterium aquatile].	25.38	528	294	25	7	504	6	463	2e-14	87.4
rs:WP_036496366	DNA topoisomerase I, partial [Nocardia sp. BMG111209].	24.20	591	347	22	7	550	22	558	2e-14	87.4
rs:WP_041460856	DNA topoisomerase I [Cronobacter sakazakii].	23.31	532	336	18	7	505	6	498	2e-14	87.4
rs:WP_032971091	DNA topoisomerase I [Cronobacter malonaticus].	23.31	532	336	18	7	505	6	498	2e-14	87.4
rs:WP_029727426	MULTISPECIES: DNA topoisomerase I [Sphingomonas].	24.67	535	314	21	7	505	4	485	2e-14	87.4
rs:WP_033235954	DNA topoisomerase I [Rhodococcus rhodochrous].	24.70	587	345	21	7	550	20	552	2e-14	87.4
rs:WP_044593861	DNA topoisomerase I [Cronobacter sakazakii].	23.31	532	336	18	7	505	6	498	2e-14	87.4
rs:WP_039350538	DNA topoisomerase I [Mumia flava].	24.01	554	332	18	1	505	1	514	2e-14	87.4
rs:WP_023887959	DNA topoisomerase I [Eikenella corrodens].	25.50	545	301	22	7	505	6	491	2e-14	87.4
rs:WP_005659000	DNA topoisomerase I [Dethiosulfovibrio peptidovorans].	23.93	539	307	21	7	504	17	493	2e-14	87.0
rs:WP_010373718	DNA topoisomerase I [Weissella cibaria].	24.44	536	306	20	7	505	32	505	2e-14	87.0
rs:WP_004861033	MULTISPECIES: topoisomerase I [Enterobacteriaceae].	24.58	533	328	19	7	505	6	498	2e-14	87.4
rs:WP_026827998	DNA topoisomerase I [Exiguobacterium sibiricum].	25.57	528	311	20	7	504	6	481	2e-14	87.0
rs:WP_010245426	DNA topoisomerase I [Peptoniphilus rhinitidis].	24.24	524	322	22	7	504	6	480	2e-14	87.0
rs:WP_010491323	DNA topoisomerase I [Paenibacillus elgii].	25.10	526	319	19	7	504	6	484	2e-14	87.0
tr:J8BJA9_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.14	350	219	11	277	606	25	358	2e-14	86.7
rs:WP_034559735	DNA topoisomerase I [Carnobacterium gallinarum].	24.28	523	323	18	7	504	7	481	2e-14	87.0
rs:WP_038248833	DNA topoisomerase I [Wolbachia endosymbiont of Glossina morsitans morsitans].	24.20	529	324	18	7	504	4	486	2e-14	87.4
rs:WP_018651935	topoisomerase I [Actinobacillus capsulatus].	24.67	454	283	18	79	505	84	505	2e-14	87.4
rs:WP_015423678	DNA topoisomerase I [uncultured Termite group 1 bacterium].	24.01	529	323	19	7	505	6	485	2e-14	87.4
rs:WP_040969433	DNA topoisomerase I [Mesorhizobium sp. ORS3324].	25.00	544	314	23	4	505	1	492	2e-14	87.4
rs:WP_016621297	DNA topoisomerase I [Enterococcus faecalis].	24.57	525	319	19	7	504	7	481	2e-14	87.0
rs:WP_033131079	DNA topoisomerase I [Aeromonas sp. AE235].	22.30	538	337	17	7	505	6	501	2e-14	87.4
rs:WP_028597444	DNA topoisomerase I [Paenibacillus pasadenensis].	23.87	532	322	20	5	505	4	483	2e-14	87.0
tr:A0A073KNM5_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.48	541	333	18	7	505	22	523	2e-14	87.4
rs:WP_040363681	DNA topoisomerase I [Commensalibacter intestini].	24.50	555	315	25	7	510	5	506	2e-14	87.4
rs:WP_043708385	DNA topoisomerase I [Weissella cibaria].	24.44	536	306	20	7	505	32	505	2e-14	87.0
rs:WP_018835882	MULTISPECIES: DNA topoisomerase I [Streptomyces].	25.43	460	272	17	97	505	86	525	2e-14	87.4
rs:WP_037753604	DNA topoisomerase I [Streptomyces sp. CNQ-525].	25.43	460	272	17	97	505	86	525	2e-14	87.4
tr:K2B5V4_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	28.11	402	217	17	47	414	1	364	2e-14	87.0
rs:WP_032088847	DNA topoisomerase I [Bacillus aquimaris].	26.01	419	266	12	112	505	82	481	2e-14	87.0
tr:K8C0K8_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.31	532	336	18	7	505	20	512	2e-14	87.4
tr:B4U2W8_STREM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.36	518	327	18	7	504	33	500	2e-14	87.0
rs:WP_014364053	DNA topoisomerase I [Rickettsia canadensis].	24.73	546	321	23	7	510	4	501	2e-14	87.4
rs:WP_029565595	DNA topoisomerase I [Bacillus cibi].	25.05	535	314	21	112	607	82	568	2e-14	87.0
rs:WP_037399137	MULTISPECIES: DNA topoisomerase I [Serratia].	26.56	448	263	19	88	505	87	498	2e-14	87.4
rs:WP_029152330	DNA topoisomerase I [Microbacterium gubbeenense].	24.32	551	324	21	7	505	8	517	2e-14	87.4
rs:WP_039480851	DNA topoisomerase I [Pectobacterium carotovorum].	25.77	454	281	18	88	513	88	513	2e-14	87.4
rs:WP_029281361	DNA topoisomerase I [Bacillus indicus].	25.05	535	314	21	112	607	82	568	2e-14	87.0
rs:WP_014509854	DNA topoisomerase I [Thermus thermophilus].	24.40	545	313	25	5	505	17	506	2e-14	87.4
rs:WP_005229621	DNA topoisomerase I [Enterococcus casseliflavus].	24.38	525	320	18	7	504	7	481	2e-14	87.0
rs:WP_027330922	DNA topoisomerase I [Marinimicrobium agarilyticum].	24.72	449	270	16	88	505	98	509	2e-14	87.4
gp:CP003312_1799	DNA topoisomerase I [Cronobacter sakazakii ES15]	23.31	532	336	18	7	505	20	512	2e-14	87.4
rs:WP_012285560	DNA topoisomerase I [Caulobacter sp. K31].	24.31	547	324	24	4	510	1	497	2e-14	87.4
rs:XP_012450480	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Gossypium raimondii].	24.61	516	297	20	47	505	344	824	2e-14	87.4
rs:WP_041399266	DNA topoisomerase I [Sphaerobacter thermophilus].	24.49	543	316	22	7	504	2	495	2e-14	87.0
rs:WP_014292698	topoisomerase I [Oceanimonas sp. GK1].	23.58	547	332	21	3	505	2	506	2e-14	87.4
rs:WP_043941141	DNA topoisomerase I [Weissella cibaria].	24.44	536	306	20	7	505	32	505	2e-14	87.0
rs:WP_026712288	DNA topoisomerase I [Flavobacterium daejeonense].	25.33	529	293	23	7	504	6	463	2e-14	87.4
rs:WP_045066573	DNA topoisomerase I [Rhodococcus sp. AD45].	24.70	587	345	21	7	550	20	552	2e-14	87.4
rs:WP_028294382	DNA topoisomerase I [Oceanobacter kriegii].	23.39	543	332	18	7	505	6	508	2e-14	87.4
tr:R8K356_BACCE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.14	350	219	11	277	606	25	358	2e-14	86.7
rs:WP_012408434	DNA topoisomerase I [Nostoc punctiforme].	24.72	445	285	14	91	505	66	490	2e-14	87.0
rs:WP_024048967	DNA topoisomerase [Negativicoccus succinicivorans].	22.81	526	323	21	7	504	38	508	2e-14	87.0
rs:WP_014953328	DNA topoisomerase I [alpha proteobacterium HIMB5].	24.06	611	357	26	7	581	4	543	2e-14	87.4
rs:WP_027363825	DNA topoisomerase I [Desulfotomaculum alcoholivorax].	23.29	614	371	23	5	586	4	549	2e-14	87.0
tr:S2QZA6_LACPA	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	26.13	463	271	19	1	443	1	412	2e-14	85.9
tr:J3CRJ2_9BRAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952}; Flags: Precursor;	23.84	537	328	20	4	505	26	516	2e-14	87.4
rs:WP_035966600	DNA topoisomerase I [Bradyrhizobium sp. YR681].	23.84	537	328	20	4	505	1	491	2e-14	87.4
rs:WP_024941857	DNA topoisomerase I [Aeromonas hydrophila].	22.12	538	338	16	7	505	6	501	2e-14	87.4
rs:WP_017813666	DNA topoisomerase I [Paenibacillus sp. A9].	23.19	526	326	18	7	504	6	481	2e-14	87.0
rs:WP_029724461	DNA topoisomerase I [Sphingomonas sp. JGI 0001003-D23].	24.67	535	314	21	7	505	4	485	2e-14	87.4
rs:WP_022564615	DNA topoisomerase I [Candidatus Pantoea carbekii].	26.48	423	255	14	107	504	103	494	2e-14	87.4
rs:WP_005813282	DNA topoisomerase I [Desulfitobacterium hafniense].	25.30	577	329	24	5	553	4	506	2e-14	87.0
rs:WP_035670243	DNA topoisomerase I [Flavobacterium sp. 83].	26.13	532	285	27	7	504	6	463	2e-14	87.4
rs:WP_028483388	MULTISPECIES: DNA topoisomerase I [unclassified Aminicenantes].	23.37	522	327	19	7	505	6	477	2e-14	87.0
rs:WP_041789304	DNA topoisomerase I, partial [Rhodomicrobium vannielii].	27.37	464	281	20	80	505	46	491	2e-14	87.4
tr:W7C9Q7_9LIST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	26.63	383	236	13	147	504	1	363	2e-14	86.3
rs:WP_043556342	DNA topoisomerase I [Aeromonas bestiarum].	22.22	540	335	17	7	505	6	501	2e-14	87.4
rs:WP_003638823	DNA topoisomerase I [Lactobacillus pentosus].	25.89	533	300	22	7	505	34	505	2e-14	87.0
tr:W8PPG8_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.24	561	324	24	7	510	8	524	2e-14	87.4
rs:WP_011738364	DNA topoisomerase I [Candidatus Ruthia magnifica].	25.33	529	306	21	7	510	6	470	2e-14	87.0
tr:L2L4T1_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.09	235	157	7	318	544	1	231	2e-14	84.7
rs:WP_030161843	DNA topoisomerase I [Glycomyces sp. NRRL B-16210].	24.24	561	324	24	7	510	12	528	2e-14	87.4
tr:K1UET1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78504.1}; Flags: Fragment;	26.71	292	178	11	210	491	3	268	2e-14	84.0
rs:WP_038541104	DNA topoisomerase I [Bacillus sp. X1(2014)].	25.30	419	268	13	112	504	82	481	2e-14	87.0
rs:WP_022945094	topoisomerase I [Pseudoalteromonas ruthenica].	23.49	545	328	18	7	505	6	507	2e-14	87.4
rs:WP_031430985	hypothetical protein [Vibrio parahaemolyticus].	23.14	592	372	20	7	546	3	563	2e-14	87.0
rs:XP_009137998	PREDICTED: uncharacterized protein LOC103862037 isoform X2 [Brassica rapa].	27.10	524	294	24	47	510	381	876	2e-14	87.4
rs:WP_046099430	DNA topoisomerase I [Staphylococcus carnosus].	23.72	527	319	19	7	504	6	478	2e-14	87.0
rs:WP_038176919	DNA topoisomerase I [Vibrio pacinii].	23.96	455	303	14	69	505	74	503	2e-14	87.0
rs:WP_019610476	DNA topoisomerase I [Nocardiopsis sp. CNS639].	24.27	548	331	20	7	505	26	538	2e-14	87.4
rs:WP_011791321	DNA topoisomerase I [Desulfovibrio vulgaris].	24.00	450	281	15	93	505	63	488	2e-14	87.0
tr:A0A0A1GXE3_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.61	233	138	10	281	498	17	238	2e-14	84.0
gpu:CP011047_2854	DNA topoisomerase I [Cronobacter sakazakii]	23.31	532	336	18	7	505	20	512	2e-14	87.0
rs:WP_008385546	DNA topoisomerase I [Rhodovulum sp. PH10].	23.99	542	323	23	4	505	1	493	2e-14	87.4
rs:WP_010940644	DNA topoisomerase I [Desulfovibrio vulgaris].	24.00	450	281	15	93	505	63	488	2e-14	87.0
rs:WP_023650178	DNA topoisomerase III family protein, partial [Vibrio parahaemolyticus].	27.23	235	152	7	7	234	5	227	2e-14	84.0
rs:WP_019746651	MULTISPECIES: DNA topoisomerase I [Rhodococcus].	24.96	589	341	22	7	550	20	552	2e-14	87.4
rs:WP_017011370	topoisomerase I [Enterovibrio calviensis].	24.40	459	296	17	69	505	74	503	2e-14	87.0
rs:WP_011250042	endonuclease [Thermococcus kodakarensis].	25.65	347	220	11	4	333	2	327	2e-14	87.4
rs:WP_011250042	endonuclease [Thermococcus kodakarensis].	26.20	271	169	7	330	589	828	1078	8e-08	66.2
rs:WP_008230948	DNA topoisomerase I [Roseobacter sp. CCS2].	24.95	549	318	23	4	512	1	495	2e-14	87.0
rs:WP_003946104	MULTISPECIES: DNA topoisomerase I [Rhodococcus].	24.96	589	341	22	7	550	20	552	2e-14	87.4
tr:A0A0D3DH53_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo7g115010.1};	26.72	524	296	23	47	510	911	1406	2e-14	87.4
rs:WP_009745737	DNA topoisomerase I [Capnocytophaga sp. oral taxon 338].	22.33	515	326	14	7	504	6	463	2e-14	87.0
rs:WP_017781938	topoisomerase I [Aeromonas hydrophila].	22.12	538	338	16	7	505	6	501	2e-14	87.0
rs:WP_015078479	DNA topoisomerase I [Anabaena sp. 90].	24.44	446	284	15	91	505	66	489	2e-14	87.0
gpu:CP011125_5547	DNA topoisomerase I [Sandaracinus amylolyticus]	24.59	549	323	23	7	505	6	513	2e-14	87.4
tr:F3HNN0_PSEYM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH60950.1};	36.00	125	76	2	56	180	12	132	2e-14	82.8
rs:WP_046200490	DNA topoisomerase I [Porphyromonas gulae].	23.22	534	301	20	7	504	5	465	2e-14	87.0
rs:WP_035588535	DNA topoisomerase I [Hippea jasoniae].	23.42	619	375	21	7	599	4	549	2e-14	87.0
rs:WP_014389293	DNA topoisomerase I [Flavobacterium indicum].	24.62	528	298	23	7	504	6	463	2e-14	87.0
tr:F6IRS7_LACPE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.89	533	300	22	7	505	34	505	2e-14	87.0
rs:WP_004803752	DNA topoisomerase I [Eggerthia catenaformis].	24.18	612	373	20	7	596	5	547	2e-14	87.0
rs:WP_020712052	hypothetical protein [Acidobacteriaceae bacterium KBS 89].	22.32	587	336	22	7	516	6	549	2e-14	87.4
rs:WP_045799666	DNA topoisomerase I [Rickettsia bellii].	24.82	544	323	21	7	510	4	501	2e-14	87.0
rs:WP_015232833	DNA topoisomerase I, archaeal [Caldisphaera lagunensis].	25.77	551	327	23	7	531	18	512	2e-14	87.0
rs:WP_041800896	DNA topoisomerase I [Rhodopseudomonas palustris].	24.63	540	321	22	4	505	1	492	2e-14	87.0
rs:WP_043135968	DNA topoisomerase I [Aeromonas salmonicida].	22.22	540	335	17	7	505	6	501	2e-14	87.0
tr:A0A098EKZ4_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.82	529	317	19	7	504	6	479	2e-14	87.0
tr:K1SY50_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC65527.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC65527.1}; Flags: Fragment;	27.46	193	117	4	373	549	4	189	2e-14	83.6
gp:CP002904_1030	DNA topoisomerase I [Streptococcus equi subsp. zooepidemicus ATCC 35246]	23.36	518	327	18	7	504	33	500	2e-14	87.0
rs:WP_031445426	DNA topoisomerase I [Arenibacter algicola].	24.13	518	315	19	7	504	6	465	2e-14	87.0
rs:WP_012963136	DNA topoisomerase I [Hydrogenobacter thermophilus].	23.16	570	336	18	7	561	4	486	2e-14	86.3
rs:WP_016868573	DNA topoisomerase I [Fischerella muscicola].	25.15	513	293	15	95	566	78	540	2e-14	87.0
rs:WP_043053080	DNA topoisomerase I [Streptococcus equi].	23.36	518	327	18	7	504	30	497	2e-14	87.0
rs:WP_017372301	topoisomerase I [Enterobacteriaceae bacterium LSJC7].	25.63	437	281	15	88	505	90	501	2e-14	87.0
rs:WP_015560448	DNA topoisomerase I [Roseburia intestinalis CAG:13].	24.48	531	313	25	7	504	6	481	2e-14	87.0
rs:WP_046201098	DNA topoisomerase I [Candidatus Pantoea carbekii].	26.48	423	255	14	107	504	103	494	2e-14	87.0
rs:WP_021336604	DNA topoisomerase I [Lactobacillus plantarum].	25.89	533	300	22	7	505	34	505	2e-14	87.0
rs:WP_012143178	topoisomerase I [Shewanella sediminis].	23.06	542	334	19	7	505	6	507	2e-14	87.0
rs:WP_046781988	DNA topoisomerase I [Lactococcus lactis].	25.29	522	312	22	7	504	25	492	2e-14	87.0
rs:WP_011116637	MULTISPECIES: DNA topoisomerase I [Helicobacter].	23.97	534	323	18	7	504	5	491	2e-14	87.0
tr:H6R9X3_NOCCG	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.04	591	342	22	7	550	1	537	2e-14	87.0
rs:WP_008111438	topoisomerase I [Pseudoalteromonas sp. BSi20311].	21.85	540	343	16	7	505	6	507	2e-14	87.0
rs:WP_034436080	DNA topoisomerase I [Clostridiales bacterium S5-A11].	22.81	526	323	21	7	504	38	508	2e-14	87.0
rs:WP_044542577	DNA topoisomerase I [Bradyrhizobium sp. LTSP885].	24.02	537	327	21	4	505	1	491	2e-14	87.0
rs:WP_019052099	DNA topoisomerase I [Sphingobium xenophagum].	25.10	526	312	22	7	505	4	474	2e-14	87.0
rs:WP_016086606	DNA topoisomerase 1 [Bacillus cereus].	25.42	421	266	16	112	505	82	481	2e-14	86.7
tr:M4E5G3_BRARP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.10	524	294	24	47	510	384	879	2e-14	87.4
rs:WP_027482820	DNA topoisomerase I [Deinococcus pimensis].	24.29	564	322	25	5	515	3	514	2e-14	86.7
rs:WP_038254792	DNA topoisomerase I [Xenorhabdus bovienii].	24.24	458	299	15	69	505	66	496	2e-14	87.0
rs:WP_006880965	topoisomerase I [Vibrio brasiliensis].	23.85	457	301	16	69	505	74	503	2e-14	87.0
rs:WP_022488349	DNA topoisomerase [Acidaminococcus sp. CAG:542].	25.92	625	357	27	7	598	6	557	2e-14	86.7
rs:WP_017151250	DNA topoisomerase I [Bacillus sp. FJAT-13831].	25.54	419	268	13	112	505	82	481	2e-14	86.7
rs:WP_012073135	topoisomerase I [Actinobacillus succinogenes].	24.04	545	330	20	3	505	2	504	2e-14	87.0
rs:WP_011191333	MULTISPECIES: DNA topoisomerase [Aeromonas].	26.28	529	301	23	107	603	74	545	2e-14	86.7
rs:WP_002677701	DNA topoisomerase I [Treponema denticola].	25.09	530	307	24	7	504	24	495	2e-14	87.0
rs:WP_027530037	DNA topoisomerase I [Bradyrhizobium sp. WSM3983].	24.02	537	327	20	4	505	1	491	2e-14	87.0
rs:WP_000246606	hypothetical protein, partial [Streptococcus agalactiae].	25.05	483	293	20	7	472	25	455	2e-14	85.9
rs:WP_004288696	DNA topoisomerase III [Bacteroides eggerthii].	21.04	613	406	23	4	590	1	561	2e-14	86.7
rs:WP_036105439	DNA topoisomerase I [Mangrovibacter sp. MFB070].	24.02	533	331	19	7	505	6	498	2e-14	87.0
rs:WP_039192312	MULTISPECIES: hypothetical protein [unclassified Thaumarchaeota (miscellaneous)].	22.28	624	400	23	5	606	4	564	2e-14	86.7
rs:WP_042446727	DNA topoisomerase I [Rhodococcus erythropolis].	24.96	589	341	22	7	550	20	552	2e-14	87.0
rs:WP_006709842	DNA topoisomerase, partial [Serratia symbiotica].	26.24	202	136	3	315	505	2	201	2e-14	82.8
rs:WP_004407604	DNA topoisomerase III, partial [Pseudomonas syringae].	31.58	171	105	4	386	548	1	167	2e-14	84.0
rs:WP_028112289	DNA topoisomerase I [Ferrimonas kyonanensis].	23.34	527	352	15	7	505	6	508	2e-14	87.0
rs:WP_040759101	DNA topoisomerase III, partial [Sporosarcina newyorkensis].	29.07	227	144	7	333	548	1	221	2e-14	85.5
rs:WP_011227691	DNA topoisomerase I [Thermus thermophilus].	23.99	542	319	23	5	505	17	506	2e-14	87.0
rs:WP_044589223	DNA topoisomerase I [Bradyrhizobium sp. LTSPM299].	24.02	537	327	21	4	505	1	491	2e-14	87.0
rs:XP_009137997	PREDICTED: uncharacterized protein LOC103862037 isoform X1 [Brassica rapa].	27.10	524	294	24	47	510	383	878	2e-14	87.4
rs:WP_029269775	DNA topoisomerase I [Virgibacillus alimentarius].	25.42	421	268	13	112	505	82	483	2e-14	86.7
rs:WP_041326303	DNA topoisomerase I [Ruminococcus champanellensis].	23.68	587	348	22	7	568	20	531	2e-14	86.7
tr:A0A078CBA8_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.72	524	296	23	47	510	371	866	2e-14	87.4
tr:D4LCS4_RUMC1	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.68	587	348	22	7	568	5	516	2e-14	86.7
rs:WP_013557841	DNA topoisomerase I [Deinococcus maricopensis].	24.76	630	342	26	5	579	4	556	2e-14	87.0
rs:WP_015964649	DNA topoisomerase I [Enterobacteriaceae bacterium strain FGI 57].	24.12	539	323	21	7	505	6	498	2e-14	87.0
tr:H0SCA3_9BRAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.11	454	290	17	86	505	5	442	2e-14	87.0
rs:WP_041099958	DNA topoisomerase I [Bacillus badius].	27.12	424	256	15	112	505	82	482	2e-14	86.7
rs:WP_035922521	DNA topoisomerase I, partial [Kordiimonas gwangyangensis].	23.85	545	316	22	4	505	1	489	2e-14	87.0
tr:A0A068EXT8_9LEPT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.18	564	320	22	7	524	12	519	2e-14	86.7
rs:WP_013155942	DNA topoisomerase I [Nocardiopsis dassonvillei].	24.27	548	331	20	7	505	26	538	2e-14	87.0
rs:WP_007477343	DNA topoisomerase I [Bartonella melophagi].	25.27	459	263	21	97	505	65	493	2e-14	87.0
rs:WP_036889231	hypothetical protein, partial [Prevotella aurantiaca].	27.16	232	144	7	331	550	1	219	2e-14	85.1
rs:WP_026730539	DNA topoisomerase I [Flavobacterium denitrificans].	24.81	524	302	21	7	504	6	463	2e-14	87.0
rs:WP_031834052	DNA topoisomerase III, partial [Staphylococcus aureus].	30.99	171	116	2	375	544	19	188	2e-14	84.7
rs:WP_023575396	DNA topoisomerase I [Flavobacterium saliperosum].	24.67	527	299	23	7	504	6	463	2e-14	87.0
rs:WP_012545297	DNA topoisomerase I [Thermodesulfovibrio yellowstonii].	23.41	628	376	24	7	595	9	570	2e-14	87.0
rs:WP_010524349	DNA topoisomerase I [Nesterenkonia sp. F].	24.73	562	315	24	7	505	12	528	2e-14	87.0
tr:F9N727_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.43	542	343	20	88	601	51	548	2e-14	86.7
tr:W4RZL4_9XANT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE49104.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAE49104.1};	32.89	152	82	4	413	549	7	153	2e-14	84.0
rs:WP_046746464	DNA topoisomerase I [Microbacterium sp. Ag1].	22.45	548	333	18	7	505	8	512	2e-14	87.0
rs:WP_001286952	DNA topoisomerase I [Bacillus cereus].	25.65	421	265	15	112	505	82	481	2e-14	86.7
rs:XP_012450479	PREDICTED: uncharacterized protein LOC105773277 isoform X1 [Gossypium raimondii].	24.61	516	297	20	47	505	344	824	2e-14	87.0
rs:WP_022337852	DNA topoisomerase [Clostridium sp. CAG:433].	24.08	623	358	28	7	595	6	547	2e-14	86.7
tr:E3HZ27_RHOVT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	27.37	464	281	20	80	505	46	491	2e-14	87.0
rs:WP_042658666	DNA topoisomerase I [Aeromonas allosaccharophila].	22.49	538	336	16	7	505	6	501	2e-14	87.0
rs:WP_033562926	DNA topoisomerase I [Sphingobacteriaceae bacterium DW12].	24.83	451	265	14	89	504	59	470	2e-14	86.7
rs:WP_046559052	DNA topoisomerase I [Arsukibacterium ikkense].	24.89	438	284	14	88	505	83	495	2e-14	87.0
rs:WP_002338418	hypothetical protein, partial [Enterococcus faecium].	31.07	177	112	6	52	225	2	171	2e-14	82.4
rs:WP_013306390	DNA topoisomerase I [Maribacter sp. HTCC2170].	24.28	519	313	18	7	504	6	465	2e-14	87.0
rs:WP_037245763	DNA topoisomerase I [Roseovarius sp. MCTG156(2b)].	23.92	577	311	27	4	510	1	519	2e-14	87.0
rs:WP_028558260	DNA topoisomerase I [Paenibacillus sp. URHA0014].	27.02	433	253	20	107	504	77	481	2e-14	86.7
rs:WP_045050014	DNA topoisomerase I [Chromobacterium violaceum].	25.09	546	315	22	7	510	6	499	2e-14	86.7
rs:WP_041894333	DNA topoisomerase I [Myroides profundi].	24.32	518	312	19	7	504	6	463	2e-14	86.7
rs:WP_010470849	DNA topoisomerase I [Acaryochloris sp. CCMEE 5410].	24.84	475	297	17	91	544	65	500	2e-14	86.7
rs:WP_018628260	DNA topoisomerase I [Niabella aurantiaca].	24.72	538	295	20	7	505	6	472	2e-14	87.0
rs:WP_038641989	DNA topoisomerase I [Pseudoalteromonas sp. OCN003].	23.53	544	327	20	7	505	6	505	2e-14	87.0
rs:WP_039171518	DNA topoisomerase I [Gallibacterium genomosp. 1].	24.49	441	281	16	88	505	93	504	2e-14	87.0
rs:WP_006011464	DNA topoisomerase I [Glaciecola pallidula].	25.17	433	279	14	93	505	99	506	2e-14	87.0
tr:T0U0C6_9ENTE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.38	222	147	7	318	531	1	218	2e-14	83.2
rs:WP_038067626	DNA topoisomerase I [Thioclava dalianensis].	25.81	496	290	23	4	475	1	442	2e-14	87.0
rs:WP_023028183	DNA topoisomerase I [Corynebacterium sp. KPL1824].	24.71	522	309	23	40	505	30	523	2e-14	87.0
rs:WP_007438736	DNA topoisomerase I [Acetobacteraceae bacterium AT-5844].	24.21	537	320	23	7	505	5	492	2e-14	87.0
rs:WP_016961327	topoisomerase I [Enterovibrio norvegicus].	22.86	538	336	18	7	505	6	503	2e-14	87.0
rs:WP_025223630	DNA topoisomerase I [Methylophilaceae bacterium 11].	24.62	532	322	22	7	504	5	491	2e-14	86.7
tr:C2QFW7_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.65	421	265	15	112	505	52	451	3e-14	86.7
rs:WP_002839970	toprim domain protein, partial [Finegoldia magna].	27.73	238	148	8	7	240	4	221	3e-14	83.2
rs:WP_042061362	DNA topoisomerase I [Aeromonas allosaccharophila].	22.49	538	336	16	7	505	6	501	3e-14	86.7
rs:WP_004945205	topoisomerase I [Serratia plymuthica].	25.97	439	277	16	88	505	87	498	3e-14	86.7
rs:WP_011174282	DNA topoisomerase I [Thermus thermophilus].	23.99	546	314	24	5	505	17	506	3e-14	86.7
rs:WP_019628805	topoisomerase I [Moritella marina].	22.95	549	328	21	7	505	6	509	3e-14	87.0
rs:WP_045811600	DNA topoisomerase I [Brevundimonas sp. KM4].	24.96	561	302	25	7	510	4	502	3e-14	86.7
rs:WP_029552434	DNA topoisomerase I [Thermocrinis sp. GBS].	24.69	486	290	19	91	561	58	482	3e-14	86.3
rs:WP_039538908	DNA topoisomerase I [Ruegeria sp. ANG-R].	24.70	575	306	25	4	510	1	516	3e-14	86.7
sp:TOP1_RICBR	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.82	544	323	21	7	510	4	501	3e-14	86.7
rs:WP_011693180	DNA topoisomerase I [Arthrobacter sp. FB24].	24.86	555	316	22	7	505	12	521	3e-14	87.0
rs:WP_006857504	DNA topoisomerase I [Roseburia intestinalis].	24.48	531	313	25	7	504	6	481	3e-14	86.7
tr:Q07L73_RHOP5	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.54	542	323	22	2	505	24	517	3e-14	87.0
rs:WP_043618220	DNA topoisomerase I [Chromobacterium violaceum].	25.09	546	315	22	7	510	6	499	3e-14	86.7
rs:WP_013008503	DNA topoisomerase I [Deferribacter desulfuricans].	25.31	573	328	26	7	541	6	516	3e-14	86.7
rs:WP_002668452	DNA topoisomerase I [Treponema denticola].	25.09	530	307	24	7	504	2	473	3e-14	86.7
rs:WP_009092271	protein TopB, partial [Elizabethkingia anophelis].	30.73	205	120	7	295	487	1	195	3e-14	82.4
rs:WP_002850920	DNA topoisomerase I [Campylobacter fetus].	25.05	531	304	21	5	505	4	470	3e-14	86.3
rs:WP_020183595	DNA topoisomerase I [Methylotenera sp. 1P/1].	24.62	532	322	22	7	504	5	491	3e-14	86.7
gpu:CP009507_2218	DNA topoisomerase I [Methanosarcina siciliae HI350]	24.07	565	354	20	8	548	6	519	3e-14	86.7
rs:WP_035472386	DNA topoisomerase I [Alistipes sp. 627].	22.56	523	319	16	8	505	1	462	3e-14	86.7
rs:WP_029939487	DNA topoisomerase I [Thiomicrospira sp. MA2-6].	24.10	527	306	18	7	505	5	465	3e-14	86.7
rs:WP_041531522	DNA topoisomerase I, partial [Pelobacter carbinolicus].	25.43	464	272	18	88	505	58	493	3e-14	86.7
tr:H5V9T9_HELBI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.73	443	276	15	170	594	166	573	3e-14	86.7
rs:WP_018321114	DNA topoisomerase I [Bradyrhizobium sp. WSM2793].	23.55	535	332	19	4	505	1	491	3e-14	86.7
rs:WP_008134073	MULTISPECIES: topoisomerase I [Pseudoalteromonas].	22.00	541	341	17	7	505	6	507	3e-14	86.7
rs:WP_028772459	DNA topoisomerase I [Shewanella waksmanii].	22.98	544	332	18	7	505	6	507	3e-14	86.7
rs:WP_011878312	DNA topoisomerase I [Desulfotomaculum reducens].	22.90	607	369	21	3	580	2	538	3e-14	86.7
rs:WP_028345613	DNA topoisomerase I [Bradyrhizobium elkanii].	23.69	536	330	20	4	505	1	491	3e-14	86.7
rs:WP_004715579	topoisomerase I [Yersinia rohdei].	25.51	439	279	17	88	505	93	504	3e-14	86.7
rs:WP_031844272	DNA topoisomerase III, partial [Staphylococcus aureus].	29.89	184	119	5	7	188	5	180	3e-14	82.4
rs:WP_045657725	DNA topoisomerase I [Clostridiaceae bacterium BRH_c20a].	23.60	627	374	25	5	599	7	560	3e-14	86.7
tr:X0RW50_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.32	440	291	14	88	505	105	524	3e-14	86.7
rs:WP_036887859	hypothetical protein, partial [Prevotella bivia].	27.15	221	138	6	331	539	1	210	3e-14	84.7
rs:WP_041748256	DNA topoisomerase I [Bradyrhizobium sp. S23321].	23.74	535	331	19	4	505	1	491	3e-14	86.7
rs:WP_033960908	DNA topoisomerase I [Psychroserpens sp. PAMC 27130].	25.57	524	300	22	7	505	6	464	3e-14	86.7
tr:A0A066WP21_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.67	527	299	21	7	504	13	470	3e-14	86.7
rs:WP_005636823	MULTISPECIES: DNA topoisomerase III [Bacteroidales].	21.15	610	409	21	4	590	1	561	3e-14	86.3
rs:WP_020262396	hypothetical protein [Aminicenantes bacterium SCGC AAA252-O11].	23.37	522	327	19	7	505	6	477	3e-14	86.7
rs:WP_043762019	DNA topoisomerase I [Aeromonas taiwanensis].	22.22	540	335	17	7	505	6	501	3e-14	86.7
rs:WP_009815756	DNA topoisomerase I [Roseovarius sp. 217].	23.83	575	314	27	4	510	1	519	3e-14	86.7
rs:WP_042979410	DNA topoisomerase I [Bacillus mycoides].	25.36	422	265	12	112	505	82	481	3e-14	86.3
rs:WP_009459295	MULTISPECIES: DNA topoisomerase I [Fischerella].	25.34	513	292	16	95	566	78	540	3e-14	86.7
rs:WP_017575781	DNA topoisomerase I [Nocardiopsis kunsanensis].	23.91	548	333	20	7	505	26	538	3e-14	86.7
rs:WP_016860420	DNA topoisomerase I [Fischerella muscicola].	24.71	510	299	15	95	566	78	540	3e-14	86.7
tr:X6T0G3_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.09	235	157	7	318	544	1	231	3e-14	84.7
rs:WP_020959337	DNA topoisomerase I [Geobacillus sp. JF8].	22.62	619	387	19	7	598	6	559	3e-14	86.3
rs:WP_005790119	MULTISPECIES: DNA topoisomerase III [Bacteroides].	21.15	610	409	22	4	590	1	561	3e-14	86.3
rs:WP_016115962	MULTISPECIES: DNA topoisomerase 1 [Bacillus].	25.30	419	269	13	112	505	82	481	3e-14	86.3
rs:WP_018780929	MULTISPECIES: DNA topoisomerase I [Bacillus].	25.30	419	269	13	112	505	82	481	3e-14	86.3
rs:WP_025245756	DNA topoisomerase I [Candidatus Sodalis pierantonius].	25.47	428	276	15	88	499	84	484	3e-14	86.7
rs:WP_018458334	DNA topoisomerase I [Bradyrhizobium sp. WSM4349].	23.84	537	328	20	4	505	1	491	3e-14	86.7
rs:WP_044656926	DNA topoisomerase I, partial [Bacteroides acidifaciens].	27.20	250	160	6	4	245	1	236	3e-14	83.2
rs:WP_036223571	hypothetical protein [Mesoaciditoga lauensis].	26.00	573	335	22	7	562	6	506	3e-14	86.7
rs:WP_035639421	hypothetical protein, partial [Bradyrhizobium sp. ORS 375].	25.11	454	290	17	86	505	21	458	3e-14	86.7
rs:WP_021888524	DNA topoisomerase [Firmicutes bacterium CAG:110].	24.05	528	321	18	7	505	8	484	3e-14	86.7
rs:WP_013549702	DNA topoisomerase I [Cellulophaga algicola].	24.14	526	305	20	7	504	6	465	3e-14	86.7
tr:Q3A7H8_PELCD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.43	464	272	18	88	505	58	493	3e-14	86.7
tr:K2EKG9_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.45	548	315	19	7	510	4	496	3e-14	86.7
rs:WP_013813135	MULTISPECIES: topoisomerase I [Serratia].	25.85	441	275	17	88	505	87	498	3e-14	86.7
rs:WP_044954273	DNA topoisomerase III, partial [Faecalibacterium prausnitzii].	28.72	282	181	8	278	547	10	283	3e-14	85.5
tr:E2ZN59_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.72	282	181	8	278	547	13	286	3e-14	85.5
rs:WP_028117526	DNA topoisomerase I [Ferrimonas senticii].	22.49	547	333	18	7	505	6	509	3e-14	86.7
rs:WP_004239222	MULTISPECIES: DNA topoisomerase I [Morganella].	25.19	540	313	22	7	505	6	495	3e-14	86.7
rs:WP_046022277	DNA topoisomerase I [Magnetospira sp. QH-2].	25.00	544	312	21	4	505	1	490	3e-14	86.7
rs:WP_011816400	DNA topoisomerase I [Yersinia enterocolitica].	25.86	437	280	16	88	505	93	504	3e-14	86.7
rs:WP_006321120	topoisomerase I [Serratia plymuthica].	25.97	439	277	16	88	505	87	498	3e-14	86.7
rs:WP_041876214	DNA topoisomerase I [Bdellovibrio sp. ArHS].	23.81	630	380	20	3	590	10	581	3e-14	86.7
rs:WP_007647546	topoisomerase I [Shewanella sp. HN-41].	23.48	541	333	18	7	505	6	507	3e-14	86.7
rs:WP_006743812	DNA topoisomerase I [Bacteroides coprosuis].	24.48	527	307	21	7	504	6	470	3e-14	86.7
rs:WP_028536783	DNA topoisomerase I [Paludibacterium yongneupense].	24.82	548	314	20	7	510	6	499	3e-14	86.7
rs:WP_042097930	DNA topoisomerase III, partial [Escherichia coli].	27.03	296	199	9	7	297	4	287	3e-14	83.6
rs:WP_036869928	DNA topoisomerase I, partial [Prevotella disiens].	27.98	218	134	6	326	531	3	209	3e-14	84.7
rs:WP_021704046	DNA topoisomerase I [Vibrio proteolyticus].	22.59	540	337	17	7	505	6	505	3e-14	86.7
rs:WP_046377850	DNA topoisomerase I [Rhodococcus erythropolis].	24.79	589	342	22	7	550	20	552	3e-14	86.7
rs:WP_037443114	DNA topoisomerase I [Shewanella sp. YQH10].	23.22	547	326	20	7	505	6	506	3e-14	86.7
rs:WP_046124918	DNA topoisomerase I [Lactococcus lactis].	25.29	522	312	22	7	504	27	494	3e-14	86.3
rs:WP_029739158	DNA topoisomerase I, partial [Cloacimonetes bacterium SCGC AAA252-K16].	23.31	605	368	23	7	586	6	539	3e-14	85.9
rs:WP_028163942	DNA topoisomerase I [Bradyrhizobium elkanii].	23.74	535	331	19	4	505	1	491	3e-14	86.7
rs:WP_044337412	DNA topoisomerase I [Bacillus aquimaris].	23.66	524	327	17	7	505	6	481	3e-14	86.3
rs:WP_012151940	DNA topoisomerase I [Rickettsia bellii].	24.82	544	323	21	7	510	4	501	3e-14	86.7
rs:WP_029667746	hypothetical protein, partial [Calescamantes bacterium JGI 0000106-I17].	24.67	450	285	15	88	504	59	487	3e-14	86.3
rs:WP_007375380	DNA topoisomerase I [Pseudoalteromonas sp. Bsw20308].	22.00	541	341	17	7	505	6	507	3e-14	86.7
rs:WP_042620614	DNA topoisomerase I [Corynebacterium marinum].	24.52	469	288	17	86	505	77	528	3e-14	86.7
rs:WP_027559642	MULTISPECIES: DNA topoisomerase I [Bradyrhizobium].	23.84	537	328	20	4	505	1	491	3e-14	86.7
rs:WP_026294208	DNA topoisomerase I [Saccharibacter floricola].	23.41	551	322	24	7	510	5	502	3e-14	86.7
rs:WP_005169368	topoisomerase I [Yersinia enterocolitica].	25.86	437	280	16	88	505	93	504	3e-14	86.7
rs:WP_041517486	DNA topoisomerase I [Flavobacterium hibernum].	25.24	527	296	23	7	504	6	463	3e-14	86.7
rs:WP_045821525	DNA topoisomerase I [Williamsia sp. ARP1].	24.46	552	325	20	7	505	19	531	3e-14	86.7
rs:WP_031826166	DNA topoisomerase III, partial [Staphylococcus aureus].	29.89	184	119	5	7	188	5	180	3e-14	82.0
rs:WP_035709856	DNA topoisomerase I [Bradyrhizobium sp. CCBAU 43298].	23.98	538	326	21	4	505	1	491	3e-14	86.7
rs:WP_011835151	DNA topoisomerase I [Lactococcus lactis].	25.29	522	312	22	7	504	27	494	3e-14	86.3
rs:WP_008735261	topoisomerase I [Alcanivorax pacificus].	21.55	543	345	16	7	505	6	511	3e-14	86.7
rs:WP_035658494	DNA topoisomerase I [Flavobacterium sp. EM1321].	24.67	527	299	21	7	504	6	463	3e-14	86.7
rs:WP_002111378	DNA topoisomerase I [Bacillus cereus].	25.54	419	268	14	112	505	82	481	3e-14	86.3
rs:WP_024473153	DNA topoisomerase I [Morganella morganii].	25.19	540	313	22	7	505	6	495	3e-14	86.7
rs:WP_028870147	DNA topoisomerase I [Psychromonas arctica].	23.57	543	355	20	69	593	76	576	3e-14	86.7
rs:WP_034811450	DNA topoisomerase I [[Eubacterium] sulci].	26.19	527	302	22	8	505	1	469	3e-14	86.3
tr:U0FRZ6_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.96	589	341	22	7	550	1	533	3e-14	86.7
rs:WP_013760650	DNA topoisomerase I [Porphyromonas asaccharolytica].	23.65	520	318	20	7	505	8	469	3e-14	86.7
tr:C3APD2_BACMY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.30	419	269	13	112	505	75	474	3e-14	86.3
rs:WP_016131882	DNA topoisomerase 1 [Bacillus cereus].	25.30	419	269	13	112	505	82	481	3e-14	86.3
rs:WP_023251570	DNA topoisomerase III, partial [Salmonella enterica].	25.32	233	161	5	8	236	5	228	3e-14	83.2
rs:WP_032981332	DNA topoisomerase I [Cronobacter malonaticus].	23.31	532	336	18	7	505	6	498	3e-14	86.7
gp:CP002094_1249	DNA topoisomerase I [Lactococcus lactis subsp. cremoris NZ9000]	25.29	522	312	22	7	504	8	475	3e-14	86.3
rs:WP_043734521	DNA topoisomerase I [Lactococcus lactis].	25.29	522	312	22	7	504	29	496	3e-14	86.3
rs:WP_042015614	DNA topoisomerase I [Aeromonas caviae].	22.12	538	338	16	7	505	6	501	3e-14	86.7
rs:WP_025422046	DNA topoisomerase I [Sodalis praecaptivus].	24.94	437	284	15	88	505	84	495	3e-14	86.7
rs:WP_042001259	DNA topoisomerase I [Capnocytophaga canimorsus].	25.24	523	301	22	7	504	6	463	3e-14	86.7
rs:WP_002331394	hypothetical protein [Enterococcus faecalis].	28.09	235	157	7	318	544	1	231	3e-14	85.1
rs:WP_019369891	DNA topoisomerase I [Sphingomonas sp. ATCC 31555].	25.24	519	320	20	7	505	4	474	3e-14	86.7
gpu:CP009506_2210	DNA topoisomerase I [Methanosarcina siciliae T4/M]	24.07	565	354	20	8	548	6	519	3e-14	86.7
rs:WP_039758711	DNA topoisomerase I [Bartonella queenslandensis].	24.82	548	308	25	4	505	1	490	3e-14	86.7
rs:WP_034285550	DNA topoisomerase I [Bacillus sp. 72].	25.94	424	259	15	112	504	82	481	3e-14	86.3
rs:WP_022466959	DNA topoisomerase [Subdoligranulum sp. CAG:314].	23.87	532	318	20	7	505	4	481	3e-14	86.3
rs:WP_036875141	hypothetical protein, partial [Prevotella nigrescens].	29.58	213	127	7	331	531	1	202	3e-14	84.7
rs:WP_033162726	hypothetical protein, partial [Sharpea azabuensis].	25.33	375	229	14	4	365	1	337	3e-14	85.9
rs:WP_018705151	DNA topoisomerase I [Bacillus fordii].	23.95	526	321	17	7	504	6	480	3e-14	86.3
rs:WP_036080422	DNA topoisomerase [Leptospirillum ferriphilum].	23.83	554	318	23	7	512	2	499	3e-14	86.3
rs:WP_011069349	topoisomerase I [Shigella flexneri].	24.14	551	308	22	7	505	6	498	3e-14	86.7
tr:R3K3Y6_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.09	235	157	7	318	544	1	231	3e-14	85.1
rs:WP_023573513	DNA topoisomerase I [Flavobacterium enshiense].	25.43	527	295	25	7	504	6	463	3e-14	86.7
rs:WP_034581636	DNA topoisomerase I [Helicobacter bizzozeronii].	25.73	443	276	15	170	594	168	575	3e-14	86.3
rs:WP_024334496	DNA topoisomerase I [Desulfotignum balticum].	26.09	460	278	18	93	515	63	497	3e-14	86.3
rs:WP_038272748	DNA topoisomerase I, partial [actinobacterium acAMD-2].	24.82	552	315	24	7	505	17	521	3e-14	86.7
rs:WP_008781114	DNA topoisomerase III [Bacteroides sp. 3_1_19].	20.72	613	408	19	4	590	1	561	3e-14	85.9
rs:WP_045254282	DNA topoisomerase I [Microbacterium foliorum].	22.77	549	329	19	7	505	8	511	3e-14	86.7
tr:Q8RQG8_BACCE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:BAB88976.1}; Flags: Fragment;	30.39	181	112	4	56	234	2	170	3e-14	82.0
rs:WP_031811097	DNA topoisomerase III, partial [Staphylococcus aureus].	29.89	184	119	5	7	188	5	180	3e-14	82.0
rs:WP_024968195	DNA topoisomerase I [Pantoea sp. IMH].	25.22	460	292	17	69	505	68	498	3e-14	86.7
rs:WP_036982852	DNA topoisomerase I [Pseudoalteromonas sp. SCSIO_11900].	23.56	433	295	12	88	505	96	507	3e-14	86.7
tr:C2XXU4_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.54	419	268	14	112	505	52	451	3e-14	86.3
rs:WP_008902384	DNA topoisomerase I [Peptoniphilus duerdenii].	24.33	522	322	17	7	504	6	478	3e-14	86.3
tr:A0A098EWQ6_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.64	418	271	12	112	504	82	480	3e-14	86.3
tr:C3BNQ9_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.30	419	269	13	112	505	75	474	3e-14	86.3
rs:WP_016266190	DNA topoisomerase I subunit omega [Yersinia enterocolitica].	25.86	437	280	16	88	505	93	504	3e-14	86.7
rs:WP_000520436	MULTISPECIES: topoisomerase I [Vibrio].	24.45	458	297	16	69	505	76	505	3e-14	86.7
rs:WP_040266076	DNA topoisomerase I [Serratia symbiotica].	25.40	437	282	15	88	505	87	498	3e-14	86.7
rs:WP_016613225	DNA topoisomerase I [Enterococcus faecium].	24.38	525	320	19	7	504	7	481	3e-14	86.3
rs:WP_039328605	DNA topoisomerase I [Myroides sp. A21].	24.32	518	312	19	7	504	6	463	3e-14	86.3
rs:WP_020008659	DNA topoisomerase I [Salinicoccus albus].	26.18	424	267	15	107	505	77	479	3e-14	86.3
rs:WP_035396956	DNA topoisomerase I [Bacillus sp. JCM 19047].	23.24	525	326	19	7	504	6	480	3e-14	86.3
rs:WP_038633076	MULTISPECIES: DNA topoisomerase I [Yersinia].	26.30	441	273	18	88	505	93	504	3e-14	86.3
tr:I0G6C5_9BRAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.74	535	331	19	4	505	26	516	3e-14	86.7
rs:WP_023252663	DNA topoisomerase III, partial [Salmonella enterica].	25.32	233	161	5	8	236	5	228	3e-14	82.8
rs:WP_012002246	DNA topoisomerase I [Pseudothermotoga lettingae].	24.38	525	309	22	43	542	27	488	3e-14	86.3
tr:K8EI91_CARML	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.19	258	161	6	300	550	1	233	3e-14	85.1
rs:WP_005506017	topoisomerase I [Grimontia hollisae].	23.33	540	331	20	7	505	6	503	3e-14	86.3
rs:WP_046230703	DNA topoisomerase I [Paenibacillus algorifonticola].	24.05	528	320	21	7	504	6	482	3e-14	86.3
rs:WP_041705892	DNA topoisomerase I, partial [Mageeibacillus indolicus].	23.79	580	337	20	5	553	4	509	3e-14	86.3
tr:K1Y7J1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	575	336	21	7	553	6	505	3e-14	86.3
gp:CP007335_1664	hypothetical protein [Salmonella enterica subsp. enterica serovar Enteritidis str.]	25.32	233	161	5	8	236	5	228	3e-14	82.8
rs:WP_020803119	toprim domain protein, partial [Klebsiella pneumoniae].	27.03	296	199	9	7	297	4	287	3e-14	83.2
rs:WP_005278299	topoisomerase I [Yersinia bercovieri].	25.86	437	280	16	88	505	94	505	3e-14	86.3
rs:WP_031868973	DNA topoisomerase III, partial [Staphylococcus aureus].	29.89	184	119	5	7	188	5	180	3e-14	82.0
rs:WP_042082558	DNA topoisomerase I [Aeromonas veronii].	22.41	540	334	17	7	505	6	501	3e-14	86.3
rs:WP_006266880	DNA topoisomerase I [Myroides odoratimimus].	24.32	518	312	19	7	504	6	463	3e-14	86.3
rs:WP_033039332	DNA topoisomerase I [Pseudoalteromonas sp. S3431].	22.18	541	340	17	7	505	6	507	3e-14	86.3
rs:XP_002986296	hypothetical protein SELMODRAFT_123748, partial [Selaginella moellendorffii].	24.08	544	328	19	2	504	1	500	3e-14	86.3
rs:WP_018014634	topoisomerase I [Teredinibacter turnerae].	22.89	533	349	17	7	505	6	510	3e-14	86.3
rs:WP_044225531	DNA topoisomerase I [Flammeovirga pacifica].	25.71	529	298	21	7	505	6	469	3e-14	86.3
rs:WP_005191581	topoisomerase I [Yersinia intermedia].	25.52	435	284	15	88	505	93	504	3e-14	86.3
rs:WP_016650340	DNA topoisomerase I [Myroides odoratimimus].	24.32	518	312	19	7	504	6	463	3e-14	86.3
rs:WP_006259653	DNA topoisomerase I [Myroides odoratimimus].	24.32	518	312	19	7	504	6	463	3e-14	86.3
rs:WP_046228045	DNA topoisomerase I [Paenibacillus dauci].	23.19	526	326	18	7	504	6	481	3e-14	86.3
rs:WP_018280051	DNA topoisomerase I [Capnocytophaga cynodegmi].	23.76	526	305	20	7	504	6	463	3e-14	86.3
rs:WP_002160736	DNA topoisomerase I [Bacillus cereus].	25.54	419	268	14	112	505	82	481	3e-14	86.3
tr:A0A077C4A4_9RICK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.14	553	315	23	4	510	1	500	3e-14	86.3
rs:WP_008080426	topoisomerase I [Vibrio sinaloensis].	23.30	455	306	14	69	505	74	503	3e-14	86.3
rs:WP_038984721	DNA topoisomerase I [Myroides odoratimimus].	25.14	521	304	21	7	504	6	463	3e-14	86.3
rs:WP_004634250	DNA topoisomerase I [Gemella morbillorum].	24.36	431	277	15	99	504	70	476	3e-14	86.3
rs:WP_025298389	DNA topoisomerase I [Aggregatibacter actinomycetemcomitans].	24.77	440	281	16	88	505	93	504	3e-14	86.3
tr:X2MHZ5_SALEN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AHO12289.1};	25.32	233	161	5	8	236	5	228	3e-14	82.8
rs:WP_019079493	topoisomerase I [Yersinia enterocolitica].	25.86	437	280	16	88	505	93	504	3e-14	86.3
rs:WP_015868991	DNA topoisomerase I [Kosmotoga olearia].	25.00	584	322	28	7	557	6	506	3e-14	86.3
rs:WP_045165305	DNA topoisomerase I [Thermoanaerobacter cellulolyticus].	23.64	571	342	21	7	553	5	505	3e-14	86.3
rs:WP_025124920	DNA topoisomerase I [Myroides odoratimimus].	24.71	518	310	20	7	504	6	463	4e-14	86.3
rs:WP_023387866	DNA topoisomerase I [Youngiibacter fragilis].	24.76	521	321	20	7	504	6	478	4e-14	86.3
rs:WP_034622365	DNA topoisomerase I, partial [Desulfovermiculus halophilus].	23.99	546	311	22	7	510	6	489	4e-14	86.3
rs:WP_005544715	topoisomerase I [Aggregatibacter actinomycetemcomitans].	24.77	440	281	16	88	505	93	504	4e-14	86.3
tr:K9SJI8_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.38	566	326	19	5	514	3	522	4e-14	86.3
rs:WP_005165857	topoisomerase I [Yersinia enterocolitica].	25.86	437	280	16	88	505	93	504	4e-14	86.3
rs:WP_022238219	DNA topoisomerase [Clostridium sp. CAG:343].	27.04	233	156	6	7	232	6	231	4e-14	82.8
rs:WP_040955680	DNA topoisomerase I [Virgibacillus sp. SK37].	24.88	426	273	13	107	505	77	482	4e-14	85.9
rs:WP_016133223	DNA topoisomerase 1 [Bacillus cereus].	25.30	419	269	13	112	505	82	481	4e-14	85.9
rs:WP_017563077	DNA topoisomerase I [Nocardiopsis synnemataformans].	24.27	548	331	20	7	505	26	538	4e-14	86.3
rs:WP_020669716	DNA topoisomerase I [Amycolatopsis nigrescens].	24.29	564	328	23	7	510	23	547	4e-14	86.3
rs:WP_024118930	DNA topoisomerase I [Thermus thermophilus].	23.99	542	319	23	5	505	17	506	4e-14	86.3
rs:WP_031910302	DNA topoisomerase III, partial [Staphylococcus aureus].	29.89	184	119	5	7	188	5	180	4e-14	82.0
rs:WP_027323376	DNA topoisomerase I [Bacillus sp. URHB0009].	25.71	424	261	14	112	505	82	481	4e-14	85.9
rs:WP_011110334	DNA topoisomerase I [Bacillus cereus].	25.89	421	264	16	112	505	52	451	4e-14	85.9
rs:WP_002146094	DNA topoisomerase I [Bacillus cereus].	25.54	419	268	14	112	505	82	481	4e-14	85.9
rs:WP_029764539	DNA topoisomerase I, partial [Gemmatimonadetes bacterium JGI 0000112-M07].	26.29	483	283	20	7	466	6	438	4e-14	85.1
rs:WP_022434282	DNA topoisomerase [Mycoplasma sp. CAG:472].	24.14	613	368	22	7	595	5	544	4e-14	85.9
rs:WP_047151637	DNA topoisomerase I [Aneurinibacillus tyrosinisolvens].	24.76	525	318	19	7	504	6	480	4e-14	85.9
rs:WP_011328029	topoisomerase I [Pseudoalteromonas haloplanktis].	21.89	539	344	16	7	505	6	507	4e-14	86.3
rs:WP_006264644	DNA topoisomerase I [Myroides odoratimimus].	24.32	518	312	19	7	504	6	463	4e-14	86.3
rs:WP_006922415	DNA topoisomerase I [Desulfovibrio magneticus].	23.77	530	316	18	7	505	6	478	4e-14	86.3
rs:WP_013649945	topoisomerase I [Yersinia enterocolitica].	25.86	437	280	16	88	505	93	504	4e-14	86.3
rs:WP_040000940	DNA topoisomerase I [Dickeya chrysanthemi].	25.75	431	267	18	99	505	99	500	4e-14	86.3
rs:WP_023030006	DNA topoisomerase I [Corynebacterium sp. KPL1818].	24.71	522	309	23	40	505	30	523	4e-14	86.3
rs:WP_044895581	DNA topoisomerase I [Bacillus alveayuensis].	23.70	633	381	22	7	607	6	568	4e-14	85.9
rs:WP_010633259	MULTISPECIES: DNA topoisomerase I subunit omega [Aeromonas].	22.12	538	338	16	7	505	6	501	4e-14	86.3
rs:WP_037000275	DNA topoisomerase III, partial [Pseudomonas fuscovaginae].	37.96	108	58	3	307	408	2	106	4e-14	80.1
rs:WP_022656303	DNA topoisomerase I [Desulfovibrio sp. Dsv1].	25.57	442	276	16	91	505	61	476	4e-14	85.9
rs:WP_018187056	DNA topoisomerase I [Microbacterium paraoxydans].	23.90	544	331	20	7	505	8	513	4e-14	86.3
rs:WP_028245271	DNA topoisomerase I [Pseudoclavibacter soli].	23.47	605	352	20	7	566	8	546	4e-14	86.3
rs:WP_008993939	DNA topoisomerase I [Novosphingobium sp. Rr 2-17].	25.41	547	302	23	7	510	4	487	4e-14	86.3
rs:WP_045035653	DNA topoisomerase I [Photobacterium iliopiscarium].	25.55	458	292	19	69	505	74	503	4e-14	86.3
rs:WP_042072215	DNA topoisomerase I [Aeromonas enteropelogenes].	22.41	540	334	18	7	505	6	501	4e-14	86.3
rs:WP_031842634	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	27.35	234	151	7	8	234	6	227	4e-14	83.2
rs:WP_040199198	DNA topoisomerase I [Geoalkalibacter subterraneus].	26.04	457	279	15	88	505	58	494	4e-14	86.3
rs:WP_046012192	DNA topoisomerase I [Microbacterium sp. SA39].	22.84	556	329	19	7	505	8	520	4e-14	86.3
rs:WP_041699504	DNA topoisomerase I, partial [Pseudanabaena sp. PCC 7367].	24.38	566	326	19	5	514	3	522	4e-14	86.3
rs:WP_027518393	DNA topoisomerase I [Bradyrhizobium sp. WSM1417].	23.84	537	328	20	4	505	1	491	4e-14	86.3
rs:WP_005607588	topoisomerase I [Actinobacillus pleuropneumoniae].	25.16	457	277	19	79	505	84	505	4e-14	86.3
rs:WP_029444934	DNA topoisomerase I [Cellulophaga baltica].	24.02	533	297	21	7	504	6	465	4e-14	86.3
rs:WP_013631854	DNA topoisomerase I [Pedobacter saltans].	25.77	454	259	17	89	505	59	471	4e-14	86.3
rs:WP_025326222	DNA topoisomerase I [Aeromonas hydrophila].	22.12	538	338	16	7	505	6	501	4e-14	86.3
tr:K1TDW7_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC57406.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC57406.1}; Flags: Fragment;	32.29	192	106	5	357	539	15	191	4e-14	83.6
rs:WP_010447216	topoisomerase I [Vibrio rotiferianus].	22.92	541	333	20	7	505	6	504	4e-14	86.3
rs:WP_004876200	topoisomerase I [Yersinia mollaretii].	26.09	437	279	16	88	505	94	505	4e-14	86.3
rs:WP_020428718	DNA topoisomerase I [Vibrio fluvialis].	24.51	457	298	15	69	505	77	506	4e-14	86.3
tr:T1C850_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD78317.1}; Flags: Fragment;	27.94	247	163	8	210	451	6	242	4e-14	82.8
rs:WP_022243320	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:45].	23.32	446	283	16	93	504	63	483	4e-14	85.9
rs:WP_038913983	DNA topoisomerase I [Dickeya zeae].	25.74	439	278	17	88	505	95	506	4e-14	86.3
rs:WP_027567322	DNA topoisomerase I [Bradyrhizobium sp. URHA0013].	23.84	537	328	20	4	505	1	491	4e-14	86.3
rs:WP_026429052	DNA topoisomerase I [Actinobaculum schaalii].	23.13	549	334	17	7	505	5	515	4e-14	86.3
rs:WP_011457582	DNA topoisomerase I [Chlamydophila felis].	22.84	591	360	22	7	563	6	534	4e-14	86.3
rs:WP_031838440	DNA topoisomerase III, partial [Staphylococcus aureus].	29.89	184	119	5	7	188	5	180	4e-14	82.0
rs:WP_010052918	DNA topoisomerase I [Carnobacterium maltaromaticum].	23.76	526	322	18	7	504	7	481	4e-14	85.9
rs:WP_007603302	DNA topoisomerase I [Bradyrhizobium sp. WSM1253].	23.74	535	331	19	4	505	1	491	4e-14	86.3
rs:WP_038094767	hypothetical protein, partial [Tumebacillus flagellatus].	23.70	540	311	20	7	504	6	486	4e-14	85.9
rs:WP_042681694	DNA topoisomerase I [Anaerosalibacter sp. ND1].	23.57	526	324	20	7	504	6	481	4e-14	85.9
rs:WP_020770795	DNA topoisomerase I [Leptospira sp. B5-022].	23.77	530	316	17	7	504	5	478	4e-14	85.9
rs:WP_036706889	DNA topoisomerase I [Paenibacillus sp. P1XP2].	23.81	525	324	18	7	504	6	481	4e-14	85.9
rs:WP_036579214	DNA topoisomerase I [Paenibacillus darwinianus].	26.28	430	260	16	107	504	77	481	4e-14	85.9
rs:WP_019134346	hypothetical protein [Kallipyga massiliensis].	21.69	521	339	13	7	506	6	478	4e-14	85.9
rs:WP_042383308	DNA topoisomerase I [Geobacillus thermoglucosidasius].	25.91	521	309	19	112	598	82	559	4e-14	85.9
rs:WP_020365116	hypothetical protein, partial [Staphylococcus epidermidis].	28.80	184	121	4	7	188	5	180	4e-14	82.0
rs:WP_005353832	topoisomerase I [Aeromonas veronii].	22.41	540	334	17	7	505	6	501	4e-14	86.3
rs:WP_012496557	DNA topoisomerase I [Rhodopseudomonas palustris].	25.65	538	312	22	7	505	4	492	4e-14	86.3
rs:WP_002355993	DNA topoisomerase, partial [Enterococcus faecium].	31.47	197	117	6	314	498	12	202	4e-14	82.4
rs:WP_019106970	DNA topoisomerase I [Peptoniphilus senegalensis].	24.62	528	315	22	7	504	6	480	4e-14	85.9
rs:WP_026962107	DNA topoisomerase I [Alicyclobacillus herbarius].	23.26	533	320	19	7	505	6	483	4e-14	85.9
tr:D3R1W8_MAGIU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.79	580	337	20	5	553	4	509	4e-14	85.9
rs:WP_004390854	topoisomerase I [Yersinia kristensenii].	26.30	441	273	18	88	505	93	504	4e-14	86.3
tr:E6QCJ7_9ZZZZ	SubName: Full=DNA topoisomerase I, plasmid (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) {ECO:0000313|EMBL:CBI04923.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI04923.1};	25.11	446	283	18	89	505	59	482	4e-14	85.9
rs:WP_032399637	DNA topoisomerase I [Rhodococcus fascians].	25.68	592	333	24	7	550	19	551	4e-14	86.3
rs:WP_028143943	MULTISPECIES: DNA topoisomerase I [Bradyrhizobium].	23.55	535	332	19	4	505	1	491	4e-14	86.3
rs:WP_010557475	topoisomerase I [Pseudoalteromonas marina].	21.56	538	347	15	7	505	6	507	4e-14	86.3
rs:WP_006792157	topoisomerase I [Alteromonadales bacterium TW-7].	21.56	538	347	15	7	505	6	507	4e-14	86.3
rs:WP_019246107	DNA topoisomerase I [Candidatus Alistipes marseilloanorexicus].	23.81	525	311	18	7	504	6	468	4e-14	85.9
rs:WP_041990434	DNA topoisomerase I [Capnocytophaga cynodegmi].	23.90	523	308	19	7	504	6	463	4e-14	85.9
rs:WP_011498828	DNA topoisomerase [Methanococcoides burtonii].	24.66	519	333	21	5	498	3	488	4e-14	85.9
rs:WP_033136942	DNA topoisomerase I [Aeromonas sp. 4287D].	22.41	540	334	17	7	505	6	501	4e-14	86.3
tr:R9X141_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.55	275	175	9	306	563	4	268	4e-14	84.7
rs:WP_029195346	DNA topoisomerase I [Paenibacillus alginolyticus].	25.47	530	309	25	7	504	6	481	4e-14	85.9
rs:WP_009829664	DNA topoisomerase I [Rhodobacteraceae bacterium HTCC2083].	25.00	552	310	24	4	510	1	493	4e-14	86.3
rs:WP_012870088	DNA topoisomerase I [Thermanaerovibrio acidaminovorans].	23.38	526	325	17	5	505	44	516	4e-14	85.9
rs:WP_012276709	topoisomerase I [Shewanella halifaxensis].	23.72	527	349	19	7	505	6	507	4e-14	86.3
rs:WP_004066812	DNA topoisomerase I [Thermococcus litoralis].	26.01	346	218	12	5	333	3	327	4e-14	85.9
rs:WP_031887577	DNA topoisomerase III, partial [Staphylococcus aureus].	30.56	180	115	5	7	184	5	176	4e-14	81.6
rs:WP_021856504	DNA topoisomerase [Firmicutes bacterium CAG:555].	24.30	572	342	19	7	555	9	512	4e-14	85.9
rs:WP_008986675	topoisomerase I [Photobacterium leiognathi].	24.67	458	296	16	69	505	76	505	4e-14	85.9
rs:WP_038560155	DNA topoisomerase I [Terribacillus aidingensis].	26.33	433	254	15	109	505	79	482	4e-14	85.9
rs:WP_028521365	DNA topoisomerase I [Ruminococcus flavefaciens].	25.71	529	311	20	7	505	5	481	4e-14	85.9
rs:WP_011697087	DNA topoisomerase I [Syntrophobacter fumaroxidans].	24.05	553	309	22	3	505	2	493	4e-14	85.9
rs:WP_028843537	DNA topoisomerase I [Pseudothermotoga elfii].	24.38	525	309	22	43	542	27	488	4e-14	85.9
rs:WP_011137815	DNA topoisomerase I [Chromobacterium violaceum].	24.91	546	316	22	7	510	6	499	4e-14	85.9
rs:WP_041370740	hypothetical protein, partial [Methylovorus glucosotrophus].	25.06	431	262	16	97	505	68	459	4e-14	85.5
rs:WP_012487618	topoisomerase I [Cellvibrio japonicus].	22.46	463	321	13	59	505	69	509	4e-14	85.9
rs:WP_022458468	DNA topoisomerase [Fusobacterium sp. CAG:439].	23.70	557	346	20	88	607	80	594	4e-14	85.9
rs:WP_018699100	hypothetical protein [Amorphus coralli].	25.23	551	317	24	7	512	4	504	4e-14	85.9
rs:WP_042545939	DNA topoisomerase I [Yersinia aldovae].	26.56	448	263	19	88	505	93	504	4e-14	85.9
rs:WP_032688111	MULTISPECIES: DNA topoisomerase I [Raoultella].	24.39	533	329	19	7	505	6	498	4e-14	85.9
tr:C6XEP4_METGS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.06	431	262	16	97	505	68	459	4e-14	85.5
rs:WP_005568750	topoisomerase I [Aggregatibacter actinomycetemcomitans].	24.77	440	281	16	88	505	93	504	5e-14	85.9
rs:WP_038950308	DNA topoisomerase I [Bradyrhizobium sp. CCBAU 15544].	23.55	535	332	19	4	505	1	491	5e-14	85.9
rs:WP_028514763	DNA topoisomerase I [Ruminococcus flavefaciens].	25.62	527	314	20	7	505	5	481	5e-14	85.9
sp:TOP1_TREPA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.25	532	309	21	7	504	20	491	5e-14	85.9
rs:WP_029081047	DNA topoisomerase I [Bradyrhizobium sp. th.b2].	24.02	537	327	21	4	505	1	491	5e-14	85.9
sp:TOP1_RICTY	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.36	546	323	22	7	510	4	501	5e-14	85.9
rs:WP_017753743	DNA topoisomerase I [Bacillus sp. ZYK].	26.50	434	251	18	108	504	78	480	5e-14	85.9
rs:WP_009057117	DNA topoisomerase I [Nitritalea halalkaliphila].	24.14	526	306	23	7	504	6	466	5e-14	85.9
rs:WP_023605764	DNA topoisomerase 1 [Vagococcus lutrae].	23.76	526	322	18	7	504	7	481	5e-14	85.9
rs:WP_004413385	topoisomerase I [Vibrio orientalis].	23.63	457	302	15	69	505	74	503	5e-14	85.9
rs:WP_042051062	MULTISPECIES: DNA topoisomerase I [Aeromonas].	22.04	540	336	17	7	505	6	501	5e-14	85.9
rs:WP_021454958	topoisomerase I [Vibrio coralliilyticus].	23.85	457	301	16	69	505	74	503	5e-14	85.9
rs:WP_040802949	hypothetical protein, partial [Nocardia concava].	23.90	590	349	21	7	550	26	561	5e-14	85.9
rs:WP_004452187	DNA topoisomerase I [Leptospira noguchii].	24.95	525	310	20	5	504	3	468	5e-14	85.5
tr:J3C607_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952}; Flags: Precursor;	25.38	528	294	24	7	504	13	470	5e-14	85.9
rs:WP_043483740	DNA topoisomerase I [Arthrobacter sp. SPG23].	24.68	555	317	22	7	505	12	521	5e-14	85.9
rs:WP_022578139	topoisomerase I [Vibrio mimicus].	24.45	458	297	16	69	505	76	505	5e-14	85.9
rs:WP_014062912	DNA topoisomerase I [Thermoanaerobacter wiegelii].	23.78	572	339	22	7	553	6	505	5e-14	85.5
rs:WP_012460546	DNA topoisomerase I [Treponema pallidum].	24.25	532	309	21	7	504	20	491	5e-14	85.9
rs:WP_005303279	MULTISPECIES: topoisomerase I [Aeromonas].	22.04	540	336	17	7	505	6	501	5e-14	85.9
rs:WP_011158669	DNA topoisomerase I [Rhodopseudomonas palustris].	25.65	538	312	22	7	505	4	492	5e-14	85.9
rs:WP_038972448	DNA topoisomerase I [Bradyrhizobium sp. CCBAU 15635].	23.55	535	332	19	4	505	1	491	5e-14	85.9
tr:F9WGN2_TRYCI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.58	419	275	14	43	452	13	399	5e-14	84.7
rs:WP_033794942	DNA topoisomerase I, partial [Bacillus sp. 105MF].	25.00	304	181	8	5	291	4	277	5e-14	82.8
rs:WP_020029559	hypothetical protein [gamma proteobacterium SCGC AAA076-P13].	23.91	552	329	19	7	512	6	512	5e-14	85.9
rs:WP_039217423	DNA topoisomerase III, partial [Clostridium novyi].	31.82	176	110	5	5	178	4	171	5e-14	81.3
tr:L8UF82_AGGAC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.34	446	271	17	88	505	93	504	5e-14	85.9
rs:WP_045012346	DNA topoisomerase I [Bradyrhizobium sp. LTSP849].	23.84	537	328	20	4	505	1	491	5e-14	85.9
rs:WP_045798880	DNA topoisomerase I [Rickettsia bellii].	24.82	544	323	21	7	510	4	501	5e-14	85.9
tr:R4I129_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.87	433	275	15	93	505	92	498	5e-14	85.9
rs:WP_017318697	DNA topoisomerase I [Mastigocladopsis repens].	23.92	602	351	18	5	566	3	537	5e-14	85.9
rs:WP_020256365	hypothetical protein [Candidatus Paceibacter normanii].	26.38	436	265	13	107	504	75	492	5e-14	85.5
rs:WP_038538797	DNA topoisomerase I [endosymbiont of Acanthamoeba sp. UWC8].	25.70	533	314	22	7	504	4	489	5e-14	85.9
rs:WP_040873068	DNA topoisomerase I, partial [delta proteobacterium NaphS2].	23.70	540	316	20	7	505	6	490	5e-14	85.9
rs:WP_038156048	DNA topoisomerase I [Vibrio sp. B183].	23.85	457	301	16	69	505	74	503	5e-14	85.9
rs:WP_009686278	MULTISPECIES: topoisomerase I [Pseudomonas].	23.53	527	347	16	7	505	6	504	5e-14	85.9
rs:WP_020250963	MULTISPECIES: hypothetical protein [unclassified Cloacimonetes].	23.13	601	374	22	7	586	6	539	5e-14	85.5
rs:WP_015501246	DNA topoisomerase I [Octadecabacter antarcticus].	25.32	553	308	26	4	510	1	494	5e-14	85.9
rs:WP_000520439	topoisomerase I [Vibrio mimicus].	24.45	458	297	16	69	505	76	505	5e-14	85.9
rs:WP_028849756	DNA topoisomerase I [Thermocrispum municipale].	23.13	549	333	19	7	505	17	526	5e-14	85.9
rs:WP_038205444	DNA topoisomerase I [Vibrio tubiashii].	23.74	455	304	15	69	505	74	503	5e-14	85.9
rs:WP_043008734	DNA topoisomerase I [Vibrio coralliilyticus].	23.85	457	301	16	69	505	74	503	5e-14	85.9
rs:WP_039036869	DNA topoisomerase I [Pseudoalteromonas sp. ECSMB14103].	21.85	540	343	16	7	505	6	507	5e-14	85.9
rs:WP_019225611	MULTISPECIES: DNA topoisomerase I [Dehalobacter].	24.63	536	318	21	3	505	2	484	5e-14	85.5
rs:WP_005213329	DNA topoisomerase I [Clostridium celatum].	25.00	524	318	21	7	505	6	479	5e-14	85.5
rs:WP_022425806	DNA topoisomerase [Catenibacterium sp. CAG:290].	25.78	419	269	14	107	505	79	475	5e-14	85.5
rs:WP_035631569	DNA topoisomerase I [Flavobacterium sp. CF136].	25.19	528	295	24	7	504	6	463	5e-14	85.9
rs:WP_006962916	topoisomerase I [Vibrio coralliilyticus].	23.85	457	301	16	69	505	74	503	5e-14	85.9
rs:WP_000520440	topoisomerase I [Vibrio mimicus].	24.45	458	297	16	69	505	76	505	5e-14	85.9
rs:WP_008131540	topoisomerase I [Pseudoalteromonas sp. BSi20480].	21.85	540	343	16	7	505	6	507	5e-14	85.9
rs:WP_007611239	DNA topoisomerase I [Bradyrhizobium sp. WSM471].	23.84	537	328	20	4	505	1	491	5e-14	85.9
rs:WP_017668615	hypothetical protein [Sandarakinorhabdus sp. AAP62].	26.12	448	264	19	103	510	71	491	5e-14	85.9
rs:WP_010130561	topoisomerase I [Microbulbifer agarilyticus].	22.37	541	342	16	7	505	6	510	5e-14	85.9
rs:WP_041964483	DNA topoisomerase I [Bacillus selenatarsenatis].	24.44	532	311	19	7	504	6	480	5e-14	85.5
rs:WP_014746067	DNA topoisomerase I [Tistrella mobilis].	23.46	537	328	19	4	505	1	489	5e-14	85.9
rs:WP_004395085	topoisomerase I [Vibrio metschnikovii].	24.73	457	297	17	69	505	76	505	5e-14	85.9
rs:WP_016338588	DNA topoisomerase I [Spiroplasma chrysopicola].	25.75	431	268	14	99	505	70	472	5e-14	85.5
rs:WP_012613184	DNA topoisomerase I [Desulfovibrio vulgaris].	24.91	538	305	21	7	505	6	483	5e-14	85.5
rs:WP_038059400	hypothetical protein, partial [Thermodesulfovibrio islandicus].	23.25	628	377	24	7	595	9	570	5e-14	85.5
rs:WP_006363417	DNA topoisomerase I [Gemella sanguinis].	23.28	524	323	18	7	504	6	476	5e-14	85.5
rs:WP_013978147	DNA topoisomerase I [Clostridium sp. SY8519].	25.45	444	273	18	93	504	63	480	5e-14	85.5
rs:WP_009340934	DNA topoisomerase I [Afipia sp. 1NLS2].	25.46	538	313	23	7	505	4	492	5e-14	85.9
tr:A0A068VC66_COFCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.38	520	295	19	47	505	389	876	5e-14	85.9
rs:WP_003251768	MULTISPECIES: DNA topoisomerase I [Geobacillus].	25.91	521	309	19	112	598	82	559	5e-14	85.5
rs:WP_013889909	DNA topoisomerase I [Helicobacter bizzozeronii].	26.29	445	271	17	170	594	176	583	5e-14	85.5
rs:WP_022258149	DNA topoisomerase [Clostridium sp. CAG:508].	23.92	531	315	18	7	504	6	480	5e-14	85.5
rs:XP_002184774	predicted protein, partial [Phaeodactylum tricornutum CCAP 1055/1].	23.49	562	342	23	7	531	2	512	5e-14	85.1
rs:WP_031905008	DNA topoisomerase III, partial [Staphylococcus aureus].	30.64	173	118	2	373	544	1	172	5e-14	83.2
rs:WP_029967608	DNA topoisomerase I [Desulfonauticus sp. A7A].	26.19	443	278	15	88	505	58	476	5e-14	85.5
rs:WP_019277761	topoisomerase I [Vibrio coralliilyticus].	23.85	457	301	16	69	505	74	503	5e-14	85.9
rs:WP_009597583	DNA topoisomerase I [Alistipes sp. HGB5].	23.35	531	305	19	7	504	6	467	5e-14	85.5
rs:WP_043635602	DNA topoisomerase I [Chromobacterium haemolyticum].	24.16	538	330	19	7	510	6	499	5e-14	85.5
rs:WP_040283448	DNA topoisomerase I [Tessaracoccus sp. SIT6].	24.14	555	325	19	7	505	6	520	5e-14	85.9
rs:WP_035044009	DNA topoisomerase I [Caulobacter henricii].	24.13	547	325	22	4	510	1	497	5e-14	85.9
rs:WP_031563836	DNA topoisomerase I [Legionella wadsworthii].	26.62	462	288	14	80	505	48	494	5e-14	85.5
rs:WP_013998399	DNA topoisomerase I [Capnocytophaga canimorsus].	25.00	524	303	22	7	505	6	464	5e-14	85.9
rs:WP_005538876	topoisomerase I [Aggregatibacter actinomycetemcomitans].	25.23	440	279	16	88	505	93	504	5e-14	85.9
rs:WP_026718357	DNA topoisomerase I [Flavobacterium gelidilacus].	24.43	524	304	22	7	504	6	463	5e-14	85.9
rs:WP_015666349	DNA topoisomerase I [Bradyrhizobium oligotrophicum].	23.69	536	330	20	4	505	1	491	5e-14	85.9
rs:WP_044746154	DNA topoisomerase I [Anoxybacillus sp. ATCC BAA-2555].	26.11	429	251	16	112	504	82	480	5e-14	85.5
rs:WP_029760461	DNA topoisomerase I [Geobacillus thermodenitrificans].	22.99	622	381	21	7	598	6	559	5e-14	85.5
rs:WP_012816917	DNA topoisomerase I [Zymomonas mobilis].	25.09	530	312	23	7	505	4	479	5e-14	85.9
rs:WP_016419510	DNA topoisomerase I [Capnocytophaga granulosa].	22.33	515	326	15	7	504	6	463	6e-14	85.9
rs:WP_047016523	DNA topoisomerase I [Streptomyces sp. CNQ-509].	25.22	460	273	17	97	505	86	525	6e-14	85.9
rs:WP_007152347	topoisomerase I [Marinobacter algicola].	21.22	542	347	16	7	505	6	510	6e-14	85.9
rs:WP_013747230	topoisomerase I [Gallibacterium anatis].	24.26	441	282	16	88	505	93	504	6e-14	85.9
rs:WP_031528031	DNA topoisomerase I [Dyadobacter crusticola].	24.71	526	302	21	7	504	6	465	6e-14	85.5
rs:WP_045680085	DNA topoisomerase I [Roseovarius sp. BRH_c41].	24.00	575	313	28	4	510	1	519	6e-14	85.9
rs:WP_042748214	DNA topoisomerase I [Lactococcus lactis].	25.29	522	312	22	7	504	27	494	6e-14	85.5
rs:WP_008960772	DNA topoisomerase I [Bradyrhizobium sp. STM 3809].	25.22	456	287	18	86	505	5	442	6e-14	85.9
rs:WP_036938706	DNA topoisomerase I [Pseudobacteroides cellulosolvens].	23.39	560	332	19	7	539	6	495	6e-14	85.5
rs:WP_002351391	toprim domain protein, partial [Enterococcus faecium].	35.14	185	106	7	5	182	4	181	6e-14	81.3
rs:WP_020280286	DNA topoisomerase I [Lactobacillus otakiensis].	25.42	421	270	16	107	504	98	497	6e-14	85.5
rs:WP_011887130	DNA topoisomerase I [Geobacillus thermodenitrificans].	22.99	622	381	21	7	598	6	559	6e-14	85.5
tr:R9PPJ5_AGAAL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.01	558	352	23	69	602	36	545	6e-14	85.5
rs:WP_019376482	DNA topoisomerase I [Virgibacillus halodenitrificans].	25.12	426	272	13	107	505	77	482	6e-14	85.5
rs:WP_004421347	DNA topoisomerase I [Leptospira noguchii].	25.29	526	307	20	5	504	3	468	6e-14	85.1
rs:WP_017618511	DNA topoisomerase I [Nocardiopsis gilva].	24.41	549	329	18	7	505	26	538	6e-14	85.9
rs:WP_042007188	DNA topoisomerase I [Aeromonas dhakensis].	22.04	540	336	17	7	505	6	501	6e-14	85.5
tr:D8EYS4_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.70	540	316	20	7	505	6	490	6e-14	85.5
tr:A0A078QP62_BACVU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.56	450	280	14	107	536	8	413	6e-14	84.7
rs:WP_009360140	DNA topoisomerase I [alpha proteobacterium HIMB114].	23.32	536	330	19	7	505	4	495	6e-14	85.5
rs:WP_003354565	DNA topoisomerase I [Bacillus smithii].	24.39	533	312	20	7	505	6	481	6e-14	85.5
rs:WP_010511451	DNA topoisomerase I [SAR324 cluster bacterium SCGC AAA001-C10].	25.49	557	299	27	7	512	6	497	6e-14	85.5
rs:WP_040389618	DNA topoisomerase I [Catenibacterium mitsuokai].	25.22	448	291	15	80	505	50	475	6e-14	85.5
rs:WP_025036761	DNA topoisomerase I [Bradyrhizobium sp. DOA9].	23.84	537	328	20	4	505	1	491	6e-14	85.5
rs:WP_011013552	DNA topoisomerase I [Corynebacterium glutamicum].	24.68	474	282	18	86	505	80	532	6e-14	85.9
tr:A0A0C2M7A6_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.69	510	292	17	95	566	78	538	6e-14	85.5
rs:WP_022135741	DNA topoisomerase [Firmicutes bacterium CAG:176].	22.54	528	329	19	7	505	8	484	6e-14	85.5
rs:WP_007392758	DNA topoisomerase I [Megasphaera sp. UPII 135-E].	24.39	537	310	21	7	504	59	538	6e-14	85.5
rs:WP_005556886	topoisomerase I [Aggregatibacter actinomycetemcomitans].	25.23	440	279	16	88	505	93	504	6e-14	85.5
rs:WP_039646065	DNA topoisomerase I [Staphylococcus hyicus].	24.44	532	309	20	7	504	6	478	6e-14	85.5
tr:K4RK22_HELHE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.03	466	288	13	85	504	56	501	6e-14	85.5
rs:WP_025850763	DNA topoisomerase I [Paenibacillus ehimensis].	24.71	526	321	19	7	504	6	484	6e-14	85.5
rs:WP_027208859	DNA topoisomerase I [Butyrivibrio hungatei].	25.62	441	278	19	93	504	57	476	6e-14	85.5
rs:WP_022874262	DNA topoisomerase I [Arthrobacter sp. PAO19].	25.27	558	311	26	7	505	14	524	6e-14	85.5
rs:WP_042054514	DNA topoisomerase I [Aeromonas veronii].	22.41	540	334	17	7	505	6	501	6e-14	85.5
rs:WP_020098197	DNA topoisomerase I [Microbacterium sp. 11MF].	23.90	544	331	20	7	505	8	513	6e-14	85.5
rs:WP_034991900	DNA topoisomerase I [Beijerinckia mobilis].	24.54	538	317	21	7	505	4	491	6e-14	85.5
rs:WP_038898164	DNA topoisomerase I [Vibrio harveyi].	22.45	539	338	18	7	505	6	504	6e-14	85.5
rs:WP_017609913	DNA topoisomerase I [Nocardiopsis xinjiangensis].	24.28	552	326	22	7	505	26	538	6e-14	85.5
rs:WP_039203318	DNA topoisomerase I [Aphanizomenon flos-aquae].	24.08	544	328	17	5	504	3	505	6e-14	85.5
rs:WP_045493307	DNA topoisomerase I [Pseudomonas sp. StFLB209].	23.21	530	346	17	7	505	6	505	6e-14	85.5
rs:WP_029014305	DNA topoisomerase I [Niveispirillum irakense].	25.00	540	314	19	5	505	4	491	6e-14	85.5
rs:WP_022984562	topoisomerase I [Alcanivorax sp. P2S70].	23.86	461	299	17	69	505	79	511	6e-14	85.5
rs:WP_036437057	DNA topoisomerase I [Mycoplasma elephantis].	22.66	534	331	18	5	510	6	485	6e-14	85.1
rs:WP_013292006	DNA topoisomerase I [Gallionella capsiferriformans].	26.65	544	305	24	3	505	2	492	6e-14	85.5
rs:WP_020080960	DNA topoisomerase I [Flavobacterium sp. SCGC AAA160-P02].	26.10	525	294	22	7	504	6	463	6e-14	85.5
rs:WP_035186290	DNA topoisomerase I [Acidiphilium sp. JA12-A1].	25.93	540	305	26	7	505	5	490	6e-14	85.5
rs:WP_031943336	Top: DNA topoisomerase [uncultured bacterium].	26.09	529	302	23	107	603	74	545	6e-14	85.1
rs:WP_004712146	topoisomerase I [Yersinia frederiksenii].	25.75	435	283	15	88	505	93	504	6e-14	85.5
rs:WP_032598760	DNA topoisomerase I [Bacteroides fragilis].	21.97	569	372	22	4	550	1	519	6e-14	85.1
rs:WP_041035495	DNA topoisomerase I [Tolypothrix campylonemoides].	24.56	517	300	16	89	566	72	537	6e-14	85.5
rs:WP_027019239	DNA topoisomerase I [Corynebacterium sputi].	24.24	458	281	17	97	505	86	526	6e-14	85.5
rs:WP_043592348	DNA topoisomerase I [Chromobacterium haemolyticum].	24.16	538	330	19	7	510	6	499	6e-14	85.5
tr:R9KZ71_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.77	444	277	18	93	504	69	487	6e-14	85.1
rs:WP_014499436	topoisomerase I [Buchnera aphidicola].	24.39	574	335	22	5	544	4	512	6e-14	85.5
rs:WP_023593058	DNA topoisomerase I [Zymomonas mobilis].	25.09	530	312	23	7	505	4	479	6e-14	85.9
tr:F0RMD4_DEIPM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.90	611	355	22	3	568	2	547	6e-14	85.5
tr:A0A0A7LFL8_9EURY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.82	504	347	15	7	498	5	478	6e-14	85.5
rs:WP_024524613	DNA topoisomerase I [Edwardsiella hoshinae].	25.23	440	279	18	88	505	87	498	6e-14	85.5
rs:WP_041333211	DNA topoisomerase I [Marinobacter salarius].	21.36	543	345	17	7	505	6	510	6e-14	85.5
rs:WP_036278948	DNA topoisomerase I [Microbacterium sp. CH12i].	23.56	556	316	22	7	505	8	511	6e-14	85.5
rs:WP_042833103	DNA topoisomerase I [Thermoanaerobacter sp. YS13].	23.51	570	343	20	7	553	6	505	6e-14	85.1
rs:WP_010478322	endonuclease [Thermococcus zilligii].	28.01	332	204	14	4	322	2	311	6e-14	85.9
rs:WP_010478322	endonuclease [Thermococcus zilligii].	26.76	213	135	4	330	539	828	1022	3e-08	67.4
tr:F3GKX3_PSESJ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH47726.1}; Flags: Fragment;	31.98	172	106	3	97	264	3	167	6e-14	80.9
rs:WP_020444080	topoisomerase I [Psychrobacter sp. G].	24.21	442	289	14	88	505	112	531	7e-14	85.5
rs:WP_014094621	DNA topoisomerase I [Candidatus Arthromitus sp. SFB-rat-Yit].	26.76	426	261	17	107	505	77	478	7e-14	85.1
rs:WP_043851335	DNA topoisomerase I [Aeromonas sp. L_1B5_3].	22.59	540	333	18	7	505	6	501	7e-14	85.5
rs:WP_026624475	DNA topoisomerase I [Eggerthia catenaformis].	25.10	526	329	17	93	596	65	547	7e-14	85.1
rs:WP_034861517	DNA topoisomerase I [Enterobacteriaceae bacterium B14].	24.89	446	273	17	88	505	87	498	7e-14	85.5
rs:WP_041222931	DNA topoisomerase I, partial [Deinococcus proteolyticus].	23.90	611	355	22	3	568	2	547	7e-14	85.5
rs:WP_006709699	topoisomerase I [Serratia symbiotica].	25.40	437	282	15	88	505	87	498	7e-14	85.5
rs:WP_044941940	DNA topoisomerase I [Flavonifractor plautii].	22.64	583	346	23	1	553	1	508	7e-14	85.5
rs:WP_027270824	DNA topoisomerase I [Legionella sainthelensi].	25.66	534	315	17	7	504	6	493	7e-14	85.5
rs:WP_041569554	hypothetical protein, partial [Chloracidobacterium thermophilum].	24.73	546	325	22	7	506	6	511	7e-14	85.5
tr:C2PIZ8_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.42	421	266	15	112	505	75	474	7e-14	85.1
rs:WP_002404673	toprim domain protein, partial [Enterococcus faecalis].	30.51	177	113	6	52	225	11	180	7e-14	81.3
rs:WP_036826674	DNA topoisomerase I [Polaribacter sp. Hel1_85].	25.53	521	302	20	7	504	6	463	7e-14	85.5
tr:C2YVB5_BACCE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.42	421	266	15	112	505	75	474	7e-14	85.1
rs:WP_040054012	DNA topoisomerase I, partial [Candidatus Arthromitus sp. SFB-4].	26.17	428	261	17	107	505	77	478	7e-14	84.7
rs:WP_020039083	DNA topoisomerase I [Salipiger mucosus].	25.69	471	268	19	4	449	1	414	7e-14	85.5
rs:WP_025064897	DNA topoisomerase, partial [Prevotella disiens].	26.76	213	133	6	331	531	2	203	7e-14	83.6
rs:WP_019508442	DNA topoisomerase I [Pleurocapsa sp. PCC 7319].	25.91	440	262	15	107	505	90	506	7e-14	85.5
tr:A0A068RD33_9ENTR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.40	437	282	15	88	505	87	498	7e-14	85.5
rs:WP_014342408	DNA topoisomerase I [Treponema pallidum].	24.25	532	309	21	7	504	20	491	7e-14	85.1
rs:WP_032992965	DNA topoisomerase I [Cronobacter malonaticus].	23.12	532	337	18	7	505	6	498	7e-14	85.5
rs:WP_017292861	DNA topoisomerase I [Geminocystis herdmanii].	23.82	617	354	22	5	579	3	545	7e-14	85.5
rs:WP_012137309	DNA topoisomerase I subunit omega [Marinobacter lipolyticus].	22.12	547	336	18	7	505	6	510	7e-14	85.5
sp:TOP1_ZYMMO	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.09	530	312	23	7	505	4	479	7e-14	85.5
rs:WP_018282125	hypothetical protein [zeta proteobacterium SCGC AB-137-C09].	24.95	481	287	17	80	512	47	501	7e-14	85.1
rs:WP_014775458	DNA topoisomerase I [Alistipes finegoldii].	23.35	531	305	19	7	504	6	467	7e-14	85.1
rs:WP_019605119	topoisomerase I [Teredinibacter turnerae].	22.70	533	350	17	7	505	6	510	7e-14	85.5
rs:WP_027727258	DNA topoisomerase I [Treponema sp. C6A8].	24.30	535	309	21	5	504	13	486	7e-14	85.1
rs:WP_028685782	DNA topoisomerase I [Phaseolibacter flectens].	26.54	422	262	16	105	505	104	498	7e-14	85.5
rs:WP_032391302	DNA topoisomerase I [Rhodococcus fascians].	25.51	592	334	24	7	550	19	551	7e-14	85.5
rs:WP_007066093	DNA topoisomerase I [Fulvimarina pelagi].	25.36	548	315	23	4	505	1	500	7e-14	85.5
rs:WP_025727922	DNA topoisomerase I [Bacillus ginsengihumi].	24.10	527	329	18	112	607	82	568	7e-14	85.1
rs:WP_007087757	DNA topoisomerase I [Bacillus bataviensis].	24.89	442	279	15	93	504	64	482	7e-14	85.1
rs:XP_010548523	PREDICTED: uncharacterized protein LOC104819919 [Tarenaya hassleriana].	25.63	519	291	23	47	505	338	821	7e-14	85.5
rs:WP_022740904	DNA topoisomerase I [Lachnospiraceae bacterium COE1].	24.32	444	279	17	93	504	63	481	7e-14	85.1
rs:WP_021675255	DNA topoisomerase I [Peptostreptococcaceae bacterium oral taxon 113].	25.55	544	320	18	7	517	6	497	7e-14	85.1
rs:WP_006680502	DNA topoisomerase I [Actinomyces turicensis].	22.94	571	325	21	1	505	1	522	7e-14	85.5
rs:WP_006718223	DNA topoisomerase I [Desulfitobacterium metallireducens].	26.12	578	324	25	5	553	4	507	7e-14	85.1
rs:WP_042294584	DNA topoisomerase I [Candidatus Arthromitus sp. SFB-mouse-NL].	25.93	428	262	17	107	505	77	478	7e-14	85.1
rs:WP_037487916	DNA topoisomerase I [Snodgrassella alvi].	24.40	541	310	21	7	505	6	489	7e-14	85.1
rs:WP_008637892	MULTISPECIES: DNA topoisomerase I [Bacillaceae].	26.95	423	257	15	112	505	82	481	7e-14	85.1
rs:WP_014991454	topoisomerase I [Actinobacillus suis].	25.38	457	276	19	79	505	84	505	7e-14	85.5
rs:WP_026100121	DNA topoisomerase I [Microchaete sp. PCC 7126].	25.00	524	292	18	89	566	72	540	7e-14	85.5
rs:WP_005802573	DNA topoisomerase III [Bacteroides fragilis].	21.37	571	373	22	4	550	1	519	7e-14	84.7
rs:WP_011441309	DNA topoisomerase I [Rhodopseudomonas palustris].	24.91	534	321	20	7	505	4	492	7e-14	85.5
rs:WP_044825956	DNA topoisomerase I [Clostridium aceticum].	24.78	573	316	23	7	546	6	496	7e-14	85.1
rs:WP_013269241	DNA topoisomerase I [Brevundimonas subvibrioides].	24.47	474	297	16	80	510	46	501	7e-14	85.5
rs:WP_038504905	DNA topoisomerase I [Cellulophaga lytica].	24.13	518	314	18	7	504	6	464	7e-14	85.5
rs:WP_024094293	DNA topoisomerase 1 [Paenibacillus larvae].	24.48	527	318	20	7	504	6	481	7e-14	85.1
tr:K1SPC5_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC62512.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC62512.1}; Flags: Fragment;	30.00	190	112	5	357	539	1	176	7e-14	82.0
rs:WP_012848405	MULTISPECIES: topoisomerase I [Edwardsiella].	24.77	440	281	17	88	505	87	498	7e-14	85.5
rs:WP_028545144	DNA topoisomerase I [Paenibacillus taiwanensis].	25.24	531	309	21	7	504	6	481	7e-14	85.1
rs:WP_041418062	DNA topoisomerase I [Shewanella woodyi].	22.69	542	336	19	7	505	6	507	7e-14	85.5
rs:WP_007236454	topoisomerase I [marine gamma proteobacterium HTCC2080].	21.54	534	354	16	7	505	6	509	7e-14	85.5
rs:WP_007832816	DNA topoisomerase III [Bacteroides dorei].	21.19	571	374	22	4	550	1	519	7e-14	84.7
rs:WP_038825724	DNA topoisomerase I [Yersinia pseudotuberculosis].	25.17	437	283	15	88	505	93	504	7e-14	85.5
rs:WP_038823909	DNA topoisomerase I [Yersinia pseudotuberculosis].	25.17	437	283	15	88	505	93	504	7e-14	85.5
rs:WP_033200472	hypothetical protein, partial [Pseudonocardia sp. P1].	24.05	553	331	22	7	505	21	538	7e-14	85.5
rs:WP_044556338	DNA topoisomerase I [Shewanella piezotolerans].	23.06	542	334	20	7	505	6	507	7e-14	85.5
rs:WP_004434734	DNA topoisomerase I [Leptospira noguchii].	25.29	526	307	20	5	504	3	468	7e-14	84.7
rs:WP_016305480	DNA topoisomerase I [Lachnospiraceae bacterium A2].	24.58	537	307	26	7	505	6	482	7e-14	85.1
rs:WP_031844985	hypothetical protein [Staphylococcus aureus].	24.75	602	348	27	7	545	6	565	7e-14	85.1
rs:WP_014410140	DNA topoisomerase I [Rickettsia montanensis].	24.73	546	321	24	7	510	4	501	7e-14	85.1
tr:J9GR19_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJX04953.1};	30.14	209	128	5	335	531	2	204	7e-14	83.6
rs:WP_025651317	MULTISPECIES: DNA topoisomerase I [Psychrobacter].	23.97	438	291	13	88	505	108	523	7e-14	85.5
gpu:CP009508_2633	DNA topoisomerase I [Methanosarcina siciliae C2J]	23.55	569	352	20	8	548	6	519	8e-14	85.1
rs:WP_042160445	DNA topoisomerase I [Paenibacillus sp. G1].	24.20	533	312	22	7	504	6	481	8e-14	85.1
rs:WP_013620341	DNA topoisomerase I [Cellulophaga lytica].	24.13	518	314	18	7	504	6	464	8e-14	85.1
rs:WP_020252236	MULTISPECIES: hypothetical protein [unclassified Cloacimonetes].	23.31	605	368	23	7	586	6	539	8e-14	85.1
rs:WP_034852229	DNA topoisomerase I [Inquilinus limosus].	24.91	550	313	23	1	505	1	495	8e-14	85.1
rs:WP_045041611	DNA topoisomerase I [Photobacterium kishitanii].	24.67	458	296	17	69	505	74	503	8e-14	85.1
rs:WP_041208968	DNA topoisomerase I [Aeromonas jandaei].	22.59	540	333	18	7	505	6	501	8e-14	85.1
rs:WP_012562937	DNA topoisomerase I [Oligotropha carboxidovorans].	24.30	539	318	23	7	505	4	492	8e-14	85.5
rs:WP_008203491	DNA topoisomerase I [Microcystis sp. T1-4].	25.13	557	308	23	5	505	3	506	8e-14	85.1
tr:E2NPJ5_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.22	448	291	15	80	505	56	481	8e-14	85.1
rs:WP_007440320	DNA topoisomerase, partial [Candidatus Arthromitus sp. SFB-1].	26.17	428	261	17	107	505	77	478	8e-14	84.7
rs:WP_028381135	DNA topoisomerase I [Legionella cherrii].	25.65	538	312	19	7	505	6	494	8e-14	85.1
rs:WP_042543808	DNA topoisomerase I [Leucobacter komagatae].	23.83	596	346	24	7	550	20	559	8e-14	85.5
rs:WP_025278686	DNA topoisomerase I [Barnesiella viscericola].	24.13	601	339	22	7	564	6	532	8e-14	85.1
rs:WP_029098937	DNA topoisomerase I [Brevibacillus thermoruber].	24.33	526	323	20	5	504	4	480	8e-14	85.1
rs:WP_020863281	DNA topoisomerase III [Candidatus Caldiarchaeum subterraneum].	23.74	535	329	18	7	527	17	486	8e-14	84.7
rs:WP_008778023	DNA topoisomerase III [Parabacteroides sp. 20_3].	21.19	571	374	22	4	550	1	519	8e-14	84.7
rs:WP_046493073	DNA topoisomerase I [Candidatus Hamiltonella defensa].	23.58	547	318	20	7	505	6	500	8e-14	85.1
rs:WP_023484649	DNA topoisomerase I-like protein [Paenibacillus larvae].	24.48	527	318	20	7	504	6	481	8e-14	85.1
tr:A0A0B4IPU2_VIBHA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.63	539	337	18	7	505	6	504	8e-14	85.1
rs:WP_005450368	MULTISPECIES: topoisomerase I [Vibrio].	22.63	539	337	18	7	505	6	504	8e-14	85.1
rs:WP_045008032	DNA topoisomerase I [Bradyrhizobium sp. LTSP857].	24.02	537	327	20	4	505	1	491	8e-14	85.1
rs:XP_002869340	DNA topoisomerase family protein [Arabidopsis lyrata subsp. lyrata].	27.69	455	247	19	107	505	609	1037	8e-14	85.5
rs:WP_044898007	DNA topoisomerase I [Aeribacillus pallidus].	24.33	526	323	20	5	504	4	480	8e-14	85.1
rs:WP_045804530	DNA topoisomerase I [Ehrlichia muris].	25.46	546	322	22	4	510	1	500	8e-14	85.1
rs:WP_036258330	DNA topoisomerase I, partial [Mesorhizobium sp. WSM3224].	25.41	551	303	26	4	505	1	492	8e-14	85.1
tr:A0A078C0P1_BRANA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.34	524	298	21	47	510	390	885	8e-14	85.5
rs:WP_014313953	DNA topoisomerase I [Clostridium sp. BNL1100].	24.16	538	314	20	7	504	6	489	8e-14	85.1
tr:J0QG47_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.77	215	127	7	308	505	14	221	8e-14	82.4
rs:WP_010853341	DNA topoisomerase I [Cyclobacteriaceae bacterium AK24].	24.14	526	308	18	7	505	6	467	8e-14	85.1
rs:WP_045078116	DNA topoisomerase I [Peptoniphilus sp. 1-1].	24.52	526	316	21	7	504	6	478	8e-14	84.7
tr:A0A0D0ITE6_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.83	596	346	24	7	550	6	545	8e-14	85.1
rs:WP_037282401	DNA topoisomerase I [Saccharibacillus sacchari].	23.57	526	326	18	7	505	6	482	8e-14	84.7
rs:WP_005614950	topoisomerase I [Actinobacillus pleuropneumoniae].	25.16	457	277	19	79	505	84	505	8e-14	85.1
rs:WP_035757834	DNA topoisomerase I [Arthrobacter albus].	23.77	551	327	21	7	505	13	522	8e-14	85.1
rs:WP_040396702	DNA topoisomerase I [Anaerococcus senegalensis].	23.24	624	380	27	7	603	6	557	8e-14	84.7
rs:WP_001286954	DNA topoisomerase I [Bacillus cereus].	25.42	421	266	15	112	505	82	481	8e-14	84.7
rs:WP_031943451	DNA topoisomerase [uncultured bacterium].	26.09	529	302	23	107	603	74	545	9e-14	84.7
rs:WP_046008750	DNA topoisomerase I [Oleispira antarctica].	24.36	431	273	18	99	505	108	509	9e-14	85.1
rs:WP_024055748	DNA topoisomerase, partial [Streptococcus parasanguinis].	25.40	378	239	13	147	504	3	357	9e-14	84.7
rs:WP_001286971	DNA topoisomerase I [Bacillus cereus].	25.42	421	266	15	112	505	82	481	9e-14	84.7
rs:WP_001286953	DNA topoisomerase I [Bacillus cereus].	25.42	421	266	15	112	505	82	481	9e-14	84.7
rs:WP_046844366	DNA topoisomerase I ['Deinococcus soli' Cha et al. 2014].	24.96	621	340	28	2	568	5	553	9e-14	85.1
rs:WP_009197744	DNA topoisomerase I [Actinomyces sp. oral taxon 848].	24.32	551	326	20	7	505	5	516	9e-14	85.1
rs:WP_012729597	topoisomerase I [Tolumonas auensis].	24.18	546	318	23	7	505	6	502	9e-14	85.1
rs:WP_036327146	DNA topoisomerase I [Mollicutes bacterium HR2].	27.25	422	253	17	107	504	80	471	9e-14	84.7
rs:WP_035340555	DNA topoisomerase I [Bacillus hemicellulosilyticus].	23.71	523	326	17	7	504	6	480	9e-14	84.7
rs:WP_010301563	DNA topoisomerase I [Kurthia sp. JC8E].	26.87	428	252	17	112	504	82	483	9e-14	84.7
rs:WP_029789004	DNA topoisomerase I [Vibrio harveyi].	22.63	539	337	18	7	505	6	504	9e-14	85.1
rs:WP_010544015	DNA topoisomerase I [Sphingomonas elodea].	25.19	524	314	20	7	505	4	474	9e-14	85.1
rs:WP_010474837	DNA topoisomerase I [Acaryochloris sp. CCMEE 5410].	23.08	533	336	19	93	596	67	554	9e-14	84.7
rs:WP_020774334	DNA topoisomerase I [Leptospira alstonii].	23.63	529	320	19	1	505	1	469	9e-14	84.7
rs:WP_008612038	DNA topoisomerase I [Joostella marina].	24.71	518	310	20	7	504	6	463	9e-14	85.1
rs:WP_041154867	DNA topoisomerase I [Vibrio mytili].	24.57	460	294	19	69	505	75	504	9e-14	85.1
rs:WP_018644533	DNA topoisomerase I [Bradyrhizobium japonicum].	23.65	537	329	20	4	505	1	491	9e-14	85.1
rs:WP_041057468	DNA topoisomerase I [Jeotgalibacillus campisalis].	24.82	427	261	14	112	504	82	482	9e-14	84.7
rs:WP_034646182	DNA topoisomerase I [Cellulophaga geojensis].	24.13	518	314	18	7	504	6	464	9e-14	85.1
rs:WP_012471296	DNA topoisomerase I [Geobacter lovleyi].	24.95	537	317	19	7	505	6	494	9e-14	84.7
rs:WP_021078311	DNA topoisomerase I [Bradyrhizobium sp. DFCI-1].	23.98	538	326	22	4	505	1	491	9e-14	85.1
rs:WP_009144254	topoisomerase I [Succinatimonas hippei].	26.26	438	276	16	88	505	79	489	9e-14	85.1
rs:WP_016595154	topoisomerase I, partial [Yersinia pestis].	26.19	420	262	16	107	505	112	504	9e-14	84.7
rs:WP_045976753	DNA topoisomerase I [Vibrio neptunius].	23.41	457	303	15	69	505	74	503	9e-14	85.1
rs:WP_009765370	topoisomerase IA [Weissella ceti].	25.84	445	278	18	7	423	5	425	9e-14	84.7
rs:WP_034388160	DNA topoisomerase I [Deinococcus sp. YIM 77859].	24.20	624	350	25	5	579	4	553	9e-14	85.1
rs:WP_024515569	DNA topoisomerase I [Bradyrhizobium sp. Tv2a-2].	23.79	538	327	21	4	505	1	491	9e-14	85.1
rs:WP_022212330	DNA topoisomerase [Clostridium sp. CAG:265].	25.62	527	311	21	7	505	6	479	1e-13	84.7
rs:WP_022043898	DNA topoisomerase [Alistipes finegoldii CAG:68].	23.35	531	305	19	7	504	6	467	1e-13	84.7
rs:WP_039310266	DNA topoisomerase I [Pectobacterium atrosepticum].	24.31	473	302	17	69	513	69	513	1e-13	85.1
rs:WP_009800677	DNA topoisomerase I [Oceanicaulis sp. HTCC2633].	24.32	555	316	23	4	510	1	499	1e-13	85.1
rs:WP_006989665	DNA topoisomerase I [Gillisia limnaea].	25.05	523	304	21	7	505	6	464	1e-13	84.7
rs:WP_042652626	DNA topoisomerase I [Aeromonas encheleia].	22.30	538	337	16	7	505	6	501	1e-13	85.1
rs:WP_040126343	DNA topoisomerase I [Campylobacter fetus].	24.89	462	279	18	73	505	48	470	1e-13	84.7
rs:WP_046444718	DNA topoisomerase I [Catabacter hongkongensis].	25.62	527	310	22	7	505	1	473	1e-13	84.7
rs:WP_040155054	DNA topoisomerase I [Yersinia ruckeri].	26.20	439	276	17	88	505	93	504	1e-13	84.7
rs:WP_044893781	DNA topoisomerase I [Bacillus alveayuensis].	26.95	423	255	16	112	504	82	480	1e-13	84.7
rs:WP_040035700	DNA topoisomerase I [Pectobacterium carotovorum].	25.68	440	277	17	88	505	88	499	1e-13	84.7
rs:WP_041767061	DNA topoisomerase I [Leifsonia xyli].	23.65	554	326	22	7	505	8	519	1e-13	85.1
gp:AP012209_678	DNA topoisomerase [Candidatus Arthromitus sp. SFB-mouse-Yit]	26.17	428	261	17	107	505	47	448	1e-13	84.7
rs:WP_015672512	DNA topoisomerase I [Serratia marcescens].	25.11	442	277	17	88	505	89	500	1e-13	84.7
rs:WP_013615831	DNA topoisomerase I [Deinococcus proteolyticus].	24.59	427	276	15	107	504	89	498	1e-13	84.7
rs:WP_016581610	topoisomerase I, partial [Yersinia pestis].	26.19	420	262	16	107	505	112	504	1e-13	84.3
tr:Q6AGT6_LEIXX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	554	326	22	7	505	41	552	1e-13	85.1
rs:WP_036039292	DNA topoisomerase I [Bradyrhizobium yuanmingense].	23.65	537	329	20	4	505	1	491	1e-13	84.7
rs:WP_022966647	topoisomerase I [Pseudomonas caeni].	24.53	424	281	14	99	505	101	502	1e-13	84.7
rs:WP_038242556	DNA topoisomerase I [Yersinia ruckeri].	26.20	439	276	17	88	505	93	504	1e-13	84.7
tr:B8CN12_SHEPW	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.06	542	334	20	7	505	22	523	1e-13	84.7
rs:WP_024305136	DNA topoisomerase I, partial [Cloacimonetes bacterium SCGC AAA252-P10].	23.31	605	368	23	7	586	1	534	1e-13	84.7
rs:WP_022029016	DNA topoisomerase [Clostridium sp. CAG:762].	22.91	550	324	20	7	532	6	479	1e-13	84.7
rs:WP_020059168	DNA topoisomerase I [Bacillus sp. 123MFChir2].	24.05	524	325	18	7	505	6	481	1e-13	84.7
rs:WP_021037269	DNA topoisomerase I TopA [Lactococcus lactis].	25.10	522	313	22	7	504	25	492	1e-13	84.7
rs:WP_009228558	DNA topoisomerase I [Prevotella sp. oral taxon 299].	25.59	594	342	24	7	563	6	536	1e-13	84.7
rs:XP_008659454	PREDICTED: uncharacterized protein LOC103638270 isoform X2 [Zea mays].	25.76	524	317	18	36	510	317	817	1e-13	85.1
rs:WP_025831860	DNA topoisomerase I [Bacteroides stercorirosoris].	24.95	521	313	19	7	505	6	470	1e-13	84.7
rs:WP_044269192	DNA topoisomerase I [Candidatus Bacteroides timonensis].	21.19	571	374	22	4	550	1	519	1e-13	84.3
rs:WP_009579003	DNA topoisomerase I [Fulvivirga imtechensis].	24.28	523	308	19	7	504	6	465	1e-13	84.7
rs:WP_015082465	DNA topoisomerase I [Lactococcus lactis].	25.10	522	313	22	7	504	27	494	1e-13	84.7
rs:WP_044503664	DNA topoisomerase I [Megasphaera sp. NP3].	22.72	537	319	21	7	504	58	537	1e-13	84.7
rs:WP_006875905	DNA topoisomerase I [Anaerotruncus colihominis].	23.17	574	345	20	7	553	8	512	1e-13	84.7
rs:XP_004259792	DNA topoisomerase 3-alpha, putative [Entamoeba invadens IP1].	24.84	612	384	23	8	588	8	574	1e-13	84.3
rs:WP_022816092	DNA topoisomerase I [Poribacteria bacterium WGA-3G].	22.82	539	335	21	3	505	2	495	1e-13	84.7
rs:WP_039276197	DNA topoisomerase I [Pectobacterium carotovorum].	25.23	440	279	15	88	505	88	499	1e-13	84.7
tr:K1UD74_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC76190.1};	30.13	229	142	6	7	233	4	216	1e-13	81.3
tr:E6LFJ8_9ENTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.56	523	332	17	7	504	14	488	1e-13	84.7
rs:WP_032388239	DNA topoisomerase I [Rhodococcus fascians].	25.51	592	334	24	7	550	19	551	1e-13	84.7
rs:WP_034606018	hypothetical protein, partial [Chitinimonas koreensis].	23.43	559	345	16	7	546	4	498	1e-13	84.3
rs:WP_011280924	topoisomerase I [Psychrobacter arcticus].	23.98	442	290	14	88	505	108	527	1e-13	84.7
rs:WP_005834274	MULTISPECIES: DNA topoisomerase I [Bacillales].	24.19	525	325	19	5	504	4	480	1e-13	84.7
rs:WP_026666845	DNA topoisomerase I [Butyrivibrio sp. AE2005].	25.40	441	279	19	93	504	57	476	1e-13	84.3
tr:W1YBX4_9ZZZZ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ETJ39205.1}; Flags: Fragment;	40.54	111	63	3	279	387	23	132	1e-13	79.3
rs:WP_006286687	topoisomerase IA [Paenibacillus popilliae].	24.53	530	314	22	7	504	6	481	1e-13	84.3
rs:WP_045262402	DNA topoisomerase I [Microbacterium oxydans].	22.49	547	334	18	7	505	8	512	1e-13	84.7
tr:B1KNL0_SHEWM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.69	542	336	19	7	505	22	523	1e-13	84.7
rs:WP_021630176	DNA topoisomerase I [Clostridium sp. ATCC BAA-442].	22.81	583	345	23	1	553	1	508	1e-13	84.7
tr:C4UJJ0_YERRU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.20	439	276	17	88	505	68	479	1e-13	84.7
rs:WP_028449871	DNA topoisomerase I [Chitinibacter tainanensis].	25.32	545	319	19	7	510	6	503	1e-13	84.7
rs:WP_011093844	topoisomerase I [Pectobacterium atrosepticum].	24.31	473	302	17	69	513	69	513	1e-13	84.7
rs:WP_045479482	DNA topoisomerase I [Bacillus sp. TS-2].	23.95	526	321	19	7	504	6	480	1e-13	84.3
rs:WP_014915357	topoisomerase I [Pectobacterium carotovorum].	25.68	440	277	17	88	505	88	499	1e-13	84.7
rs:WP_014017919	DNA topoisomerase I [Candidatus Arthromitus sp. SFB-mouse].	26.17	428	261	17	107	505	77	478	1e-13	84.3
rs:WP_039549548	DNA topoisomerase I [Pectobacterium carotovorum].	25.68	440	277	17	88	505	88	499	1e-13	84.7
rs:WP_024640560	DNA topoisomerase I [Pseudomonas syringae].	22.89	498	306	15	43	504	25	480	1e-13	84.7
rs:WP_005806337	MULTISPECIES: DNA topoisomerase I [Candidatus Arthromitus].	26.17	428	261	17	107	505	77	478	1e-13	84.3
rs:WP_026734142	DNA topoisomerase I [Fischerella sp. PCC 9605].	25.54	513	291	16	95	566	78	540	1e-13	84.7
tr:D4E5V9_SEROD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.94	441	279	17	88	505	17	428	1e-13	84.7
rs:WP_045215568	DNA topoisomerase I [Desulfobulbus alkaliphilus].	25.17	449	287	18	86	505	50	478	1e-13	84.7
rs:WP_024723336	DNA topoisomerase I [Clostridiales bacterium VE202-03].	22.81	583	345	23	1	553	1	508	1e-13	84.7
rs:WP_007205640	DNA topoisomerase I [Loktanella vestfoldensis].	24.54	546	323	22	4	512	1	494	1e-13	84.7
rs:WP_040931294	DNA topoisomerase I, partial [Paenibacillus larvae].	25.34	442	279	14	92	504	47	466	1e-13	84.3
rs:WP_028269930	DNA topoisomerase I [Arthrobacter sp. UNC362MFTsu5.1].	24.55	550	324	20	7	505	12	521	1e-13	84.7
rs:WP_039141172	DNA topoisomerase I [Flavihumibacter solisilvae].	23.05	525	320	18	7	505	6	472	1e-13	84.7
rs:WP_039180480	DNA topoisomerase I [Leisingera sp. ANG-M7].	24.12	568	315	25	4	510	1	513	1e-13	84.7
rs:WP_018398472	DNA topoisomerase I [filamentous cyanobacterium ESFC-1].	25.78	450	282	14	91	505	74	506	1e-13	84.7
rs:WP_035375720	DNA topoisomerase I, partial [Acholeplasma axanthum].	24.57	525	308	21	7	506	6	467	1e-13	84.3
rs:WP_040366499	DNA topoisomerase I [Enterococcus italicus].	22.56	523	332	17	7	504	7	481	1e-13	84.3
tr:J9GH34_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EJX06329.1}; Flags: Fragment;	28.40	243	134	8	110	343	16	227	1e-13	81.3
rs:WP_018029297	hypothetical protein [Porphyromonas somerae].	24.32	518	312	20	7	504	6	463	1e-13	84.7
rs:WP_041077912	DNA topoisomerase I [Candidatus Rickettsia asemboensis].	26.05	453	282	18	96	510	64	501	1e-13	84.7
rs:WP_025323057	DNA topoisomerase I [Deferrisoma camini].	24.23	549	318	21	7	512	6	499	1e-13	84.3
rs:WP_031943396	DNA topoisomerase I [uncultured bacterium].	24.24	495	308	16	43	505	27	486	1e-13	84.3
rs:WP_004331586	DNA topoisomerase I [Porphyromonas asaccharolytica].	23.65	520	318	20	7	505	8	469	1e-13	84.7
rs:WP_016989276	DNA topoisomerase I [Flavobacterium sp. ACAM 123].	25.43	527	295	24	7	504	6	463	1e-13	84.7
rs:WP_014848241	DNA topoisomerase I [Zymomonas mobilis].	25.09	530	312	23	7	505	4	479	1e-13	84.7
rs:WP_039709081	DNA topoisomerase I [Actinobacillus pleuropneumoniae].	25.00	460	274	20	79	505	84	505	1e-13	84.7
tr:A0A0A8VIQ6_YERRU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.20	439	276	17	88	505	68	479	1e-13	84.7
rs:WP_008582879	DNA topoisomerase I [Niabella soli].	24.72	530	305	19	7	505	6	472	1e-13	84.7
rs:WP_028341022	DNA topoisomerase I [Bradyrhizobium elkanii].	23.98	538	326	22	4	505	1	491	1e-13	84.7
rs:WP_006309612	DNA topoisomerase I [Facklamia languida].	22.24	526	339	18	1	505	1	477	1e-13	84.3
rs:WP_014794888	MULTISPECIES: DNA topoisomerase I [Desulfitobacterium].	24.22	611	350	25	5	579	4	537	1e-13	84.3
rs:WP_005858550	DNA topoisomerase III [Parabacteroides distasonis].	21.19	571	374	22	4	550	1	519	1e-13	84.3
rs:WP_021404437	DNA topoisomerase I [Peptoclostridium difficile].	26.23	530	307	25	5	504	4	479	1e-13	84.3
tr:A0A067B5R6_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.24	458	298	16	69	505	76	505	1e-13	84.7
rs:WP_047030324	DNA topoisomerase I [Hoeflea sp. IMCC20628].	24.91	558	316	23	4	510	1	506	1e-13	84.7
rs:WP_039496180	DNA topoisomerase I [Pectobacterium carotovorum].	25.68	440	277	17	88	505	88	499	1e-13	84.7
rs:WP_024611339	DNA topoisomerase I [Pseudoalteromonas haloplanktis].	22.62	526	356	15	7	505	6	507	1e-13	84.7
rs:WP_044495257	DNA topoisomerase I [Nesterenkonia sp. NP1].	23.60	555	332	19	7	505	19	537	1e-13	84.7
rs:WP_007104511	DNA topoisomerase I [Glaciecola polaris].	25.06	431	282	14	93	505	99	506	1e-13	84.7
rs:WP_035651805	DNA topoisomerase I [Flavobacterium sp. Fl].	24.43	524	304	21	7	504	6	463	1e-13	84.7
rs:WP_013639815	DNA topoisomerase I [Acidiphilium multivorum].	25.74	540	306	26	7	505	5	490	1e-13	84.7
rs:WP_025335382	DNA topoisomerase I [Paenibacillus sabinae].	24.34	530	315	22	7	504	6	481	1e-13	84.3
rs:WP_032364536	DNA topoisomerase I [Rhodococcus fascians].	25.51	592	334	24	7	550	19	551	1e-13	84.7
rs:WP_022005878	DNA topoisomerase [Proteobacteria bacterium CAG:495].	25.14	537	304	20	7	504	4	481	1e-13	84.3
rs:WP_011941732	DNA topoisomerase I [Acidiphilium cryptum].	25.74	540	306	26	7	505	5	490	1e-13	84.7
rs:WP_032373810	DNA topoisomerase I [Rhodococcus fascians].	25.51	592	334	24	7	550	19	551	1e-13	84.7
rs:WP_035939843	DNA topoisomerase I [Knoellia aerolata].	23.63	546	334	21	7	505	14	523	1e-13	84.7
rs:WP_024581368	MULTISPECIES: DNA topoisomerase I [Bradyrhizobium].	23.98	538	326	22	4	505	1	491	1e-13	84.7
rs:WP_015730472	topoisomerase I [Pectobacterium wasabiae].	24.77	440	281	16	88	505	88	499	1e-13	84.7
rs:WP_039709549	DNA topoisomerase I [Actinobacillus pleuropneumoniae].	25.00	460	274	20	79	505	84	505	1e-13	84.7
rs:WP_018023156	hypothetical protein [Corynebacterium ulceribovis].	26.20	458	266	18	101	505	93	531	1e-13	84.7
rs:WP_009259245	DNA topoisomerase I [Lachnospiraceae bacterium 7_1_58FAA].	22.81	583	345	23	1	553	1	508	1e-13	84.3
rs:WP_034448315	DNA topoisomerase I [Cloacimonetes bacterium SCGC AAA252-E13].	23.31	605	368	23	7	586	6	539	1e-13	84.3
rs:WP_026095613	DNA topoisomerase I [Microbacterium sp. B19].	22.90	594	343	20	7	550	8	536	1e-13	84.7
rs:WP_022994440	MULTISPECIES: topoisomerase I [Alcanivorax].	23.11	476	319	14	54	505	61	513	1e-13	84.7
rs:WP_025700243	DNA topoisomerase I [Paenibacillus durus].	23.86	528	320	21	7	504	6	481	1e-13	84.3
rs:WP_022105370	DNA topoisomerase [Dialister sp. CAG:486].	23.53	527	323	19	7	505	34	508	1e-13	84.3
rs:WP_013945052	DNA topoisomerase I [Treponema paraluiscuniculi].	24.06	532	310	21	7	504	20	491	1e-13	84.3
rs:WP_025383880	DNA topoisomerase I [Yersinia similis].	25.97	439	277	17	88	505	93	504	1e-13	84.3
rs:WP_022689888	DNA topoisomerase I [Sphingomonas-like bacterium B12].	25.09	534	318	22	7	510	4	485	1e-13	84.3
rs:WP_040995667	DNA topoisomerase I, partial [Mesorhizobium sp. SOD10].	25.59	551	302	27	4	505	1	492	1e-13	84.3
rs:WP_027201850	DNA topoisomerase I [Butyricimonas virosa].	23.65	520	318	19	7	504	6	468	1e-13	84.3
rs:WP_035409985	DNA topoisomerase I [Chromohalobacter israelensis].	23.22	534	347	16	7	505	6	511	1e-13	84.3
rs:WP_032406609	DNA topoisomerase I [Rhodococcus fascians].	25.51	592	334	24	7	550	19	551	1e-13	84.7
tr:A0A024LSJ9_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.77	551	307	26	7	505	4	493	1e-13	84.3
rs:WP_024304701	DNA topoisomerase I [Cloacimonetes bacterium SCGC AAA252-N11].	23.31	605	368	23	7	586	6	539	1e-13	84.3
rs:WP_016170258	hypothetical protein [Parcubacteria bacterium SCGC AAA011-G05].	25.56	446	283	14	99	512	66	494	1e-13	84.3
rs:WP_039517280	DNA topoisomerase I [Pectobacterium carotovorum].	25.68	440	277	17	88	505	88	499	1e-13	84.3
rs:WP_010772513	DNA topoisomerase 1 [Enterococcus caccae].	23.95	526	321	18	7	504	7	481	1e-13	84.3
rs:WP_028503370	DNA topoisomerase I [Microbacterium sp. URHA0036].	22.26	548	334	18	7	505	8	512	1e-13	84.7
rs:WP_047043504	DNA topoisomerase I [Vibrio sp. CAIM 1540].	22.98	544	328	21	7	505	6	503	1e-13	84.3
rs:WP_005523284	DNA topoisomerase I [Vibrio mimicus].	24.24	458	298	16	69	505	76	505	1e-13	84.3
rs:WP_011930304	DNA topoisomerase I [Calyptogena okutanii thioautotrophic gill symbiont].	25.04	559	317	23	7	548	6	479	1e-13	84.3
rs:WP_022890767	DNA topoisomerase I [Agromyces italicus].	24.69	563	321	23	7	505	8	531	1e-13	84.3
rs:WP_025766918	DNA topoisomerase I [Vibrio parahaemolyticus].	22.92	541	333	20	7	505	6	504	1e-13	84.3
rs:WP_012974466	DNA topoisomerase I [Azospirillum lipoferum].	24.28	552	317	22	1	505	1	498	1e-13	84.3
rs:WP_039035873	DNA topoisomerase I [Shewanella sp. ECSMB14102].	24.82	419	270	14	107	505	114	507	1e-13	84.3
rs:WP_034452594	DNA topoisomerase I [Butyrivibrio sp. AE2032].	24.83	447	274	18	93	504	58	477	1e-13	84.3
rs:WP_007365501	DNA topoisomerase I [Porphyromonas uenonis].	24.81	524	307	22	7	505	8	469	1e-13	84.3
rs:WP_002715487	DNA topoisomerase I [Afipia felis].	23.93	535	325	20	7	505	4	492	1e-13	84.3
rs:WP_016843950	DNA topoisomerase I, partial [Bradyrhizobium elkanii].	23.65	537	329	21	4	505	1	491	1e-13	84.3
rs:WP_029330313	DNA topoisomerase I [Mycoplasma cloacale].	23.97	413	273	15	107	504	79	465	1e-13	84.0
rs:WP_027494469	DNA topoisomerase I [Rhodococcus sp. JG-3].	25.51	592	334	24	7	550	19	551	1e-13	84.7
rs:WP_042029403	DNA topoisomerase I [Aeromonas jandaei].	22.55	541	332	18	7	505	6	501	1e-13	84.3
rs:WP_013480650	DNA topoisomerase I [Asticcacaulis excentricus].	24.82	544	319	21	7	510	4	497	1e-13	84.3
rs:WP_032386019	DNA topoisomerase I [Rhodococcus fascians].	25.51	592	334	24	7	550	19	551	1e-13	84.7
rs:WP_021839657	DNA topoisomerase [Alistipes sp. CAG:514].	25.44	515	314	20	7	504	6	467	1e-13	84.3
rs:WP_002956759	DNA topoisomerase I [Helicobacter cinaedi].	25.06	443	290	14	89	505	59	485	1e-13	84.3
rs:WP_017496994	DNA topoisomerase I [Flavobacterium sp. WG21].	25.33	537	283	25	7	504	6	463	1e-13	84.3
rs:WP_020110968	DNA topoisomerase I [Rhodococcus sp. 114MFTsu3.1].	24.83	592	338	23	7	550	22	554	1e-13	84.3
rs:WP_026782988	DNA topoisomerase I [Pleomorphomonas koreensis].	25.00	560	304	25	7	510	4	503	1e-13	84.3
rs:WP_005236830	DNA topoisomerase I [Enterococcus casseliflavus].	24.38	525	320	19	7	504	7	481	1e-13	84.3
rs:WP_032384044	DNA topoisomerase I [Rhodococcus fascians].	25.51	592	334	24	7	550	19	551	1e-13	84.3
rs:WP_014939949	DNA topoisomerase I [Lactobacillus buchneri].	26.00	423	265	16	107	504	98	497	1e-13	84.3
tr:E8KVD5_STRVE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.57	395	239	14	136	504	14	379	1e-13	84.0
rs:WP_000520438	topoisomerase I [Vibrio sp. RC341].	24.24	458	298	16	69	505	76	505	1e-13	84.3
rs:WP_034648778	DNA topoisomerase I [Corynebacterium vitaeruminis].	24.84	471	286	18	86	505	75	528	1e-13	84.3
rs:WP_017740381	DNA topoisomerase I [Scytonema hofmanni].	24.44	532	283	18	89	566	72	538	1e-13	84.3
rs:WP_044426265	DNA topoisomerase I [Skermanella aerolata].	24.33	559	329	22	1	512	1	512	1e-13	84.3
rs:WP_027705141	DNA topoisomerase I [Zymobacter palmae].	21.93	538	348	18	7	505	6	510	1e-13	84.3
rs:WP_023454501	DNA topoisomerase I [Asticcacaulis sp. AC460].	24.31	547	325	23	4	510	1	498	1e-13	84.3
rs:WP_032369316	DNA topoisomerase I [Rhodococcus fascians].	25.51	592	334	24	7	550	19	551	1e-13	84.3
rs:WP_042524917	DNA topoisomerase I [Yersinia ruckeri].	25.63	437	281	16	88	505	93	504	1e-13	84.3
rs:WP_039291757	DNA topoisomerase I [Pectobacterium atrosepticum].	24.73	465	292	18	79	513	77	513	1e-13	84.3
tr:E2SJG9_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.19	616	369	25	7	593	5	551	1e-13	84.3
rs:WP_037057711	DNA topoisomerase I, partial [Pseudonocardia asaccharolytica].	22.89	546	339	19	7	505	42	552	1e-13	84.3
rs:WP_011506859	topoisomerase I [Chromohalobacter salexigens].	23.22	534	347	16	7	505	6	511	1e-13	84.3
rs:WP_038604242	DNA topoisomerase I, partial [Rickettsiales bacterium Ac37b].	26.90	435	265	19	107	504	75	493	1e-13	84.3
rs:WP_008981066	DNA topoisomerase I [Ruminococcaceae bacterium D16].	22.28	570	352	19	7	553	8	509	1e-13	84.3
rs:WP_016340453	DNA topoisomerase I [Spiroplasma syrphidicola].	25.29	431	270	13	99	505	70	472	1e-13	84.0
rs:WP_033115350	DNA topoisomerase I [Aeromonas sp. AE122].	22.59	540	333	17	7	505	6	501	1e-13	84.3
rs:WP_021015979	DNA topoisomerase I [Serratia sp. ATCC 39006].	23.56	539	326	21	7	505	6	498	1e-13	84.3
tr:A0A0C1NEQ2_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.47	519	299	17	89	566	72	538	1e-13	84.3
tr:R7VCK8_CAPTE	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	23.01	478	303	19	97	553	103	536	1e-13	84.3
rs:WP_005441716	DNA topoisomerase I [Saccharomonospora azurea].	23.35	561	340	19	7	510	21	548	1e-13	84.3
rs:WP_039649009	DNA topoisomerase I [Campylobacter insulaenigrae].	23.74	514	319	15	7	500	5	465	1e-13	84.0
rs:WP_003406572	DNA topoisomerase I [Clostridium butyricum].	25.48	526	313	23	7	505	6	479	1e-13	84.0
rs:WP_005504709	DNA topoisomerase I [Rothia mucilaginosa].	24.14	609	342	21	7	566	12	549	1e-13	84.3
rs:WP_035474507	DNA topoisomerase I [Gammaproteobacteria bacterium MFB021].	21.76	533	354	17	7	505	6	509	1e-13	84.3
rs:WP_043933337	DNA topoisomerase I [Bacillus sp. EB01].	26.46	427	254	15	112	505	82	481	2e-13	84.0
rs:WP_034194828	hypothetical protein, partial [Burkholderia sp. WP42].	33.33	177	98	4	375	531	4	180	2e-13	81.6
rs:WP_038885822	DNA topoisomerase I [Vibrio rotiferianus].	22.74	541	334	20	7	505	6	504	2e-13	84.3
rs:WP_013707568	DNA topoisomerase I [Desulfobacca acetoxidans].	23.56	641	369	25	7	607	6	565	2e-13	84.3
rs:WP_005962844	DNA topoisomerase I [Fusobacterium necrophorum].	22.77	527	330	20	1	504	1	473	2e-13	84.3
rs:WP_046831928	DNA topoisomerase I [Xanthomonas axonopodis].	26.40	356	225	12	107	452	75	403	2e-13	84.0
rs:WP_024341083	DNA topoisomerase I [Bradyrhizobium japonicum].	23.74	535	331	19	4	505	1	491	2e-13	84.3
tr:A0A074LLS2_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.66	541	312	20	7	505	6	487	2e-13	84.3
rs:WP_010473233	DNA topoisomerase I [Streptomyces somaliensis].	23.10	554	328	22	7	505	15	525	2e-13	84.3
rs:WP_035949104	DNA topoisomerase I [Knoellia flava].	23.58	547	333	20	7	505	11	520	2e-13	84.3
rs:WP_011585715	DNA topoisomerase I [Cytophaga hutchinsonii].	25.81	434	256	15	7	434	6	379	2e-13	84.3
rs:WP_038600921	DNA topoisomerase I [Lactococcus lactis].	25.62	523	309	23	7	504	29	496	2e-13	84.0
rs:WP_032108967	DNA topoisomerase I [Haemophilus sp. FF7].	24.83	451	287	18	79	505	82	504	2e-13	84.3
rs:WP_042855966	hypothetical protein [Escherichia coli].	31.22	189	124	5	208	391	3	190	2e-13	80.5
rs:WP_023049409	hypothetical protein [Pseudomonas putida].	25.00	476	298	14	97	555	75	508	2e-13	84.0
gpu:CP009503_1228	DNA topoisomerase I [Methanosarcina sp. WWM596]	23.39	573	360	22	1	548	39	557	2e-13	84.3
rs:WP_028780491	DNA topoisomerase I [Shewanella sp. 38A_GOM-205m].	24.82	419	270	14	107	505	114	507	2e-13	84.3
rs:WP_014084443	DNA topoisomerase I [Flavobacterium branchiophilum].	25.99	531	287	28	7	504	6	463	2e-13	84.3
rs:WP_037108519	DNA topoisomerase I [Rhodococcus fascians].	24.83	592	338	23	7	550	22	554	2e-13	84.3
rs:WP_003140856	DNA topoisomerase I [Aerococcus viridans].	22.16	519	333	16	7	504	7	475	2e-13	84.0
rs:WP_031454641	DNA topoisomerase I [Flavobacterium chungangense].	25.00	528	296	24	7	504	6	463	2e-13	84.3
rs:WP_010275225	topoisomerase I [Pectobacterium carotovorum].	25.68	440	277	17	88	505	88	499	2e-13	84.3
tr:A0A090EG08_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.59	551	302	27	4	505	1	492	2e-13	84.3
rs:WP_018193230	MULTISPECIES: hypothetical protein [unclassified Thaumarchaeota (miscellaneous)].	22.12	624	401	23	5	606	4	564	2e-13	84.0
rs:WP_037164306	DNA topoisomerase I [Rhodococcus fascians].	24.83	592	338	23	7	550	22	554	2e-13	84.3
rs:WP_019662974	DNA topoisomerase I [Rhodococcus sp. 29MFTsu3.1].	24.83	592	338	23	7	550	22	554	2e-13	84.3
rs:WP_033190107	DNA topoisomerase I [Rhodococcus fascians].	24.83	592	338	23	7	550	22	554	2e-13	84.3
rs:WP_014572601	DNA topoisomerase I [Lactococcus lactis].	25.10	522	313	22	7	504	27	494	2e-13	84.0
rs:WP_005968653	topoisomerase I [Pectobacterium wasabiae].	24.89	454	285	17	88	513	88	513	2e-13	84.3
rs:WP_021211410	DNA topoisomerase I [Lactococcus lactis].	25.10	522	313	22	7	504	29	496	2e-13	84.0
rs:WP_039196769	DNA topoisomerase I [Actinobacillus equuli].	25.11	454	281	18	79	505	84	505	2e-13	84.3
rs:WP_015237021	DNA topoisomerase I [Deinococcus peraridilitoris].	23.44	610	357	23	5	568	4	549	2e-13	84.3
rs:WP_002671672	DNA topoisomerase I [Treponema denticola].	25.19	528	309	23	7	504	24	495	2e-13	84.0
gpu:CP011509_6665	DNA topoisomerase I [Archangium gephyra]	23.94	564	326	23	7	516	89	603	2e-13	84.3
rs:WP_008967069	DNA topoisomerase I [Bradyrhizobium sp. STM 3843].	23.32	536	332	20	4	505	1	491	2e-13	84.3
rs:WP_040736674	DNA topoisomerase I [Paenibacillus alvei].	25.45	440	281	15	92	504	62	481	2e-13	84.0
rs:WP_027186352	DNA topoisomerase I [Desulfovibrio inopinatus].	23.46	520	330	19	7	505	6	478	2e-13	84.0
rs:WP_007749548	DNA topoisomerase I [Cronobacter dublinensis].	25.06	435	286	15	88	505	17	428	2e-13	84.3
rs:WP_040012981	DNA topoisomerase I, partial [Erysipelotrichaceae bacterium 3_1_53].	24.19	616	369	25	7	593	5	551	2e-13	84.0
rs:WP_041523467	DNA topoisomerase I [Gilvimarinus agarilyticus].	21.88	544	340	16	7	505	6	509	2e-13	84.3
rs:WP_044638043	DNA topoisomerase I [Siansivirga zeaxanthinifaciens].	24.90	522	304	22	7	504	6	463	2e-13	84.3
rs:WP_011676299	DNA topoisomerase I [Lactococcus lactis].	25.10	522	313	22	7	504	27	494	2e-13	84.0
rs:WP_032395241	DNA topoisomerase I [Rhodococcus fascians].	25.51	592	334	24	7	550	19	551	2e-13	84.3
rs:WP_025064910	DNA topoisomerase, partial [Prevotella disiens].	29.11	213	128	7	331	531	2	203	2e-13	82.4
rs:WP_008753063	DNA topoisomerase I [Lachnoanaerobaculum saburreum].	24.66	438	277	16	97	504	67	481	2e-13	84.0
rs:WP_045198457	DNA topoisomerase I [Rhodococcus sp. B7740].	25.51	592	334	24	7	550	19	551	2e-13	84.3
tr:A0A0D6NH25_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN65362.1};	24.23	549	322	23	7	510	5	504	2e-13	84.3
rs:WP_037187887	DNA topoisomerase I [Rhodococcus fascians].	25.51	592	334	24	7	550	19	551	2e-13	84.3
tr:A0A072TRW2_MEDTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.38	525	314	20	36	504	265	762	2e-13	84.3
rs:WP_031552313	DNA topoisomerase I [Gemella sanguinis].	22.69	520	331	17	7	504	6	476	2e-13	84.0
rs:WP_027132250	DNA topoisomerase I [Fusobacterium necrophorum].	22.77	527	330	20	1	504	1	473	2e-13	84.0
rs:WP_006036574	DNA topoisomerase I [Paenibacillus curdlanolyticus].	23.63	529	321	21	7	504	6	482	2e-13	84.0
rs:WP_037183150	DNA topoisomerase I [Rhodococcus fascians].	24.83	592	338	23	7	550	22	554	2e-13	84.3
rs:WP_024930446	DNA topoisomerase I [Methylophilus sp. OH31].	24.63	544	309	20	7	504	5	493	2e-13	84.3
rs:WP_028152767	DNA topoisomerase I [Bradyrhizobium japonicum].	23.65	537	329	20	4	505	1	491	2e-13	84.3
rs:WP_012225025	DNA topoisomerase 1 [Candidatus Microthrix parvicella].	23.79	559	336	21	1	505	1	523	2e-13	84.3
rs:WP_038399844	DNA topoisomerase I [Yersinia pseudotuberculosis].	25.17	437	283	15	88	505	93	504	2e-13	84.3
rs:WP_042013731	DNA topoisomerase I [Aeromonas fluvialis].	22.22	540	335	17	7	505	6	501	2e-13	84.3
rs:WP_029416389	DNA topoisomerase I [Brevundimonas bacteroides].	23.63	546	327	19	7	510	4	501	2e-13	84.3
rs:WP_044071284	hypothetical protein, partial [Prevotella timonensis].	29.11	213	128	7	331	531	1	202	2e-13	82.4
rs:WP_036893583	hypothetical protein, partial [Prevotella timonensis].	29.11	213	128	7	331	531	1	202	2e-13	82.4
rs:WP_047305771	DNA topoisomerase I [Pseudomonas fluorescens].	25.31	486	302	18	88	555	66	508	2e-13	84.0
rs:WP_018189947	DNA topoisomerase I [Leifsonia sp. 109].	23.69	553	327	22	7	505	8	519	2e-13	84.3
rs:WP_015588556	DNA topoisomerase [Wolbachia endosymbiont of Drosophila simulans].	24.13	460	295	15	80	504	46	486	2e-13	84.0
rs:WP_028463728	DNA topoisomerase I [Nocardia sp. 348MFTsu5.1].	23.12	545	340	16	7	505	19	530	2e-13	84.3
rs:WP_044904860	DNA topoisomerase I [[Clostridium] innocuum].	25.27	546	332	24	80	593	50	551	2e-13	84.0
rs:WP_005314340	DNA topoisomerase I [Streptomyces pristinaespiralis].	23.34	557	323	23	7	505	15	525	2e-13	84.3
rs:WP_044531588	DNA topoisomerase III, partial [Herbaspirillum sp. B65].	28.27	237	148	7	329	550	4	233	2e-13	83.6
rs:WP_019881158	MULTISPECIES: DNA topoisomerase I [Methylophilus].	24.63	544	309	20	7	504	5	493	2e-13	84.3
tr:R9A4C2_9LEPT	SubName: Full=Putative DNA topoisomerase I {ECO:0000313|EMBL:EOQ96952.1};	24.30	465	280	18	81	504	2	435	2e-13	83.6
rs:WP_025690981	DNA topoisomerase I [Paenibacillus zanthoxyli].	23.86	528	320	21	7	504	6	481	2e-13	84.0
rs:WP_016409792	DNA topoisomerase [Clostridium sp. CAG:1024].	24.58	537	313	24	3	504	2	481	2e-13	84.0
rs:WP_012725699	DNA topoisomerase I [Beutenbergia cavernae].	23.32	566	329	19	7	505	9	536	2e-13	84.3
rs:WP_009341807	DNA topoisomerase I [Raphidiopsis brookii].	24.75	505	304	15	97	568	80	541	2e-13	84.0
rs:WP_027404688	DNA topoisomerase I [Aphanizomenon flos-aquae].	23.80	542	332	16	5	504	3	505	2e-13	84.0
rs:WP_028287613	DNA topoisomerase I [Oceanicola nanhaiensis].	24.67	535	317	23	4	505	1	482	2e-13	84.0
rs:WP_025882636	DNA topoisomerase I [Porphyromonas uenonis].	24.81	524	307	22	7	505	8	469	2e-13	84.0
rs:WP_040843384	DNA topoisomerase I [Nitrospirillum amazonense].	25.00	548	314	24	1	505	1	494	2e-13	84.0
rs:WP_007347925	DNA topoisomerase I [Bartonella rattimassiliensis].	25.44	456	266	19	97	505	65	493	2e-13	84.0
rs:WP_002215352	DNA topoisomerase I [Neisseria meningitidis].	24.77	533	317	20	7	505	6	488	2e-13	84.0
rs:WP_029262798	MULTISPECIES: DNA topoisomerase I [Microbacterium].	22.30	547	335	18	7	505	8	512	2e-13	84.3
rs:WP_016563078	DNA topoisomerase [Bacteroides sp. CAG:927].	25.32	541	320	19	7	523	5	485	2e-13	84.0
rs:WP_003285574	topoisomerase I [Pseudomonas stutzeri].	22.16	537	340	18	7	505	6	502	2e-13	84.0
rs:WP_012105105	topoisomerase I [Yersinia pseudotuberculosis].	25.17	437	283	15	88	505	93	504	2e-13	84.0
rs:WP_020075496	DNA topoisomerase I [Cryocola sp. 340MFSha3.1].	23.69	553	327	22	7	505	8	519	2e-13	84.0
rs:WP_033799363	DNA topoisomerase I, partial [Bacillus pseudomycoides].	25.71	315	177	8	5	297	4	283	2e-13	80.9
rs:WP_035347842	DNA topoisomerase [Edaphobacter aggregans].	22.68	582	325	21	7	510	6	540	2e-13	84.0
rs:WP_045273629	DNA topoisomerase I [Microbacterium azadirachtae].	25.24	511	307	20	43	505	14	497	2e-13	84.0
tr:R0U479_NEIME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.49	543	322	20	7	510	6	499	2e-13	83.6
tr:S4EPX6_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EPI19509.1}; Flags: Fragment;	38.46	130	68	5	5	129	3	125	2e-13	79.0
rs:WP_013073533	DNA topoisomerase I [Zunongwangia profunda].	24.86	523	306	20	7	505	6	465	2e-13	84.0
rs:WP_011192446	topoisomerase I [Yersinia pseudotuberculosis].	25.17	437	283	15	88	505	93	504	2e-13	84.0
rs:WP_038832236	DNA topoisomerase I [Yersinia pestis].	26.19	420	262	16	107	505	112	504	2e-13	84.0
rs:WP_027431366	DNA topoisomerase I [Lachnospira multipara].	24.02	487	315	21	47	504	21	481	2e-13	84.0
rs:WP_036956550	DNA topoisomerase I [Providencia alcalifaciens].	26.64	443	269	18	88	505	95	506	2e-13	84.0
rs:WP_040516161	DNA topoisomerase I [Gordonia amarae].	23.79	580	342	19	7	535	19	549	2e-13	84.3
rs:WP_014666685	DNA topoisomerase I [Helicobacter cinaedi].	25.06	443	290	14	89	505	59	485	2e-13	84.0
tr:K4Z7C0_PAEAL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.45	440	281	15	92	504	32	451	2e-13	83.6
rs:WP_040216033	DNA topoisomerase I [Haemophilus parahaemolyticus].	25.45	448	271	18	86	505	92	504	2e-13	84.0
rs:WP_008430847	DNA topoisomerase I [Planococcus donghaensis].	24.11	531	313	21	7	504	6	479	2e-13	84.0
tr:A0A077FJB6_9RICK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.90	435	265	19	107	504	75	493	2e-13	84.0
rs:WP_020255499	hypothetical protein [Parcubacteria bacterium SCGC AAA010-E09].	22.86	595	362	21	4	580	1	516	2e-13	84.0
rs:WP_040976355	DNA topoisomerase I [Pasteurella sp. FF6].	24.62	459	278	18	79	505	82	504	2e-13	84.0
rs:WP_002328882	hypothetical protein, partial [Enterococcus faecium].	29.94	177	114	5	52	225	2	171	2e-13	79.7
rs:WP_011514221	topoisomerase I [Psychrobacter cryohalolentis].	23.98	442	290	14	88	505	112	531	2e-13	84.0
rs:WP_028494947	MULTISPECIES: DNA topoisomerase I [Microbacterium].	22.88	542	339	18	7	505	8	513	2e-13	84.0
rs:WP_038936326	DNA topoisomerase I [Bradyrhizobium japonicum].	23.65	537	329	20	4	505	1	491	2e-13	84.0
gpu:CP009967_5	DNA topoisomerase family protein [Bacillus cereus E33L]	29.82	228	130	8	282	486	1	221	2e-13	80.5
rs:WP_014699936	DNA topoisomerase [Pectobacterium sp. SCC3193].	24.77	440	281	16	88	505	88	499	2e-13	84.0
rs:WP_023570754	DNA topoisomerase I [Flavobacterium cauense].	25.05	527	297	24	7	504	6	463	2e-13	84.0
rs:WP_038953673	DNA topoisomerase I [Bradyrhizobium japonicum].	23.69	536	328	20	4	504	1	490	2e-13	84.0
rs:WP_028611049	DNA topoisomerase I [Paenibacillus harenae].	24.33	526	320	21	7	504	6	481	2e-13	84.0
rs:WP_033659367	DNA topoisomerase, partial [Enterococcus faecium].	38.46	130	68	5	5	129	4	126	2e-13	79.0
rs:WP_029455134	DNA topoisomerase I [Candidatus Pelagibacter ubique].	24.67	531	320	22	7	505	4	486	2e-13	84.0
rs:WP_033071499	DNA topoisomerase I [Pectobacterium wasabiae].	24.77	440	281	16	88	505	88	499	2e-13	84.0
rs:WP_024626956	DNA topoisomerase I [Bifidobacterium sp. A11].	22.78	553	331	21	7	505	8	518	2e-13	84.0
rs:WP_023763638	DNA topoisomerase I [Mesorhizobium sp. LNHC232B00].	25.23	547	309	24	4	505	1	492	2e-13	84.0
rs:WP_046193505	DNA topoisomerase I [Sphingomonas sp. SRS2].	24.38	525	317	21	7	505	4	474	2e-13	84.0
rs:WP_042677941	DNA topoisomerase I, partial [Pantoea sp. B40].	28.53	319	197	12	204	505	3	307	2e-13	83.6
rs:WP_044227149	DNA topoisomerase I [Phaeodactylibacter xiamenensis].	23.75	518	324	16	7	505	6	471	2e-13	84.0
rs:WP_018845833	DNA topoisomerase I [Streptomyces sp. CNT372].	22.62	557	327	21	7	505	15	525	2e-13	84.0
rs:WP_005611954	topoisomerase I [Actinobacillus pleuropneumoniae].	24.51	457	280	19	79	505	84	505	2e-13	84.0
sp:TOP1_RICPR	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.11	458	280	18	96	510	64	501	2e-13	84.0
rs:WP_044562983	DNA topoisomerase I [Azospirillum sp. B4].	24.54	546	319	23	1	505	1	494	2e-13	84.0
rs:WP_038893575	DNA topoisomerase I [Yersinia pestis].	26.19	420	262	16	107	505	112	504	2e-13	84.0
rs:WP_014494702	DNA topoisomerase I [Bradyrhizobium japonicum].	23.65	537	329	20	4	505	1	491	2e-13	84.0
tr:L0K918_HALHC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.98	631	385	25	7	607	8	567	2e-13	83.6
rs:WP_045515241	DNA topoisomerase I [Bacillus niacini].	25.18	425	261	16	112	504	82	481	2e-13	83.6
rs:WP_013028145	DNA topoisomerase I [Sideroxydans lithotrophicus].	27.58	446	246	19	107	505	77	492	2e-13	84.0
rs:WP_036676479	DNA topoisomerase I [Paenibacillus sp. MSt1].	24.52	526	322	19	7	504	6	484	2e-13	83.6
tr:G2LH23_CHLTF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.73	546	325	22	7	506	6	511	2e-13	84.0
rs:WP_009669777	topoisomerase I [gamma proteobacterium IMCC1989].	22.76	435	296	12	88	505	99	510	2e-13	84.0
rs:WP_005378351	MULTISPECIES: topoisomerase I [Vibrio].	22.92	541	333	20	7	505	6	504	2e-13	84.0
rs:WP_007540097	DNA topoisomerase I [Candidatus Aquiluna sp. IMCC13023].	23.57	577	353	18	7	550	6	527	2e-13	84.0
rs:WP_033794941	DNA topoisomerase I, partial [Bacillus sp. 105MF].	25.25	305	179	9	5	291	4	277	2e-13	80.9
rs:WP_006742126	topoisomerase I [Vibrio sp. Ex25].	22.92	541	333	20	7	505	6	504	2e-13	84.0
rs:WP_046328999	DNA topoisomerase I [Sneathia sp. Sn35].	23.14	523	314	19	7	504	14	473	2e-13	84.0
rs:WP_003428420	DNA topoisomerase [Clostridium butyricum].	25.48	526	313	23	7	505	6	479	2e-13	83.6
rs:WP_033848486	MULTISPECIES: DNA topoisomerase I [Yersinia].	25.97	439	277	17	88	505	93	504	2e-13	84.0
rs:WP_026598814	DNA topoisomerase I [Methylocystis sp. LW5].	23.78	513	311	22	34	505	18	491	2e-13	84.0
rs:WP_036430655	DNA topoisomerase I [Mycoplasma felis].	22.45	530	314	18	7	504	5	469	2e-13	83.6
rs:WP_007317029	DNA topoisomerase I [Gordonia effusa].	23.29	644	381	23	7	595	17	602	2e-13	84.0
rs:WP_022941114	topoisomerase I [Psychromonas hadalis].	22.78	641	389	24	3	598	2	581	2e-13	84.0
rs:WP_017820029	topoisomerase I [Vibrio alginolyticus].	22.92	541	333	20	7	505	6	504	2e-13	84.0
rs:WP_017258991	DNA topoisomerase I [Pedobacter arcticus].	23.45	452	278	17	86	505	56	471	2e-13	84.0
rs:WP_015277422	DNA topoisomerase I [Pseudomonas stutzeri].	22.16	537	340	18	7	505	6	502	2e-13	84.0
rs:WP_037143270	DNA topoisomerase I [Rhodococcus fascians].	24.83	592	338	23	7	550	22	554	2e-13	84.0
rs:WP_014411681	DNA topoisomerase 1 [Rickettsia prowazekii].	25.11	458	280	17	96	510	64	501	2e-13	84.0
rs:WP_010729566	hypothetical protein, partial [Enterococcus faecium].	38.46	130	68	5	5	129	4	126	2e-13	78.6
tr:A0A094SR49_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KGA21208.1};	25.88	595	319	27	7	550	14	537	2e-13	84.0
rs:WP_027522980	DNA topoisomerase I [Bradyrhizobium sp. Ec3.3].	23.65	537	329	20	4	505	1	491	2e-13	84.0
rs:WP_005600888	topoisomerase I [Actinobacillus pleuropneumoniae].	24.73	457	279	19	79	505	84	505	2e-13	84.0
rs:WP_027635064	DNA topoisomerase I [Clostridium butyricum].	25.48	526	313	23	7	505	6	479	2e-13	83.6
rs:WP_021755795	DNA topoisomerase I [Leifsonia xyli].	23.70	557	322	23	7	505	8	519	2e-13	84.0
rs:WP_019539088	hypothetical protein [Proteiniphilum acetatigenes].	24.42	520	313	19	7	504	6	467	2e-13	84.0
rs:WP_041607638	DNA topoisomerase I [Halobacteroides halobius].	22.98	631	385	25	7	607	13	572	2e-13	83.6
rs:WP_021674956	toprim domain protein, partial [Peptostreptococcaceae bacterium oral taxon 113].	29.52	210	129	9	7	213	6	199	2e-13	79.7
rs:WP_005390711	MULTISPECIES: topoisomerase I [Vibrio].	22.92	541	333	20	7	505	6	504	2e-13	84.0
rs:WP_016589524	topoisomerase I [Yersinia pestis].	25.17	437	283	15	88	505	93	504	2e-13	84.0
rs:WP_019242321	DNA topoisomerase I [Bacillus massilioanorexius].	24.64	418	271	11	112	504	82	480	2e-13	83.6
rs:WP_007424321	DNA topoisomerase I [Acidiphilium sp. PM].	25.74	540	306	26	7	505	5	490	2e-13	84.0
rs:WP_027831857	DNA topoisomerase I [Marinobacter sp. HL-58].	20.74	540	352	14	7	505	6	510	2e-13	84.0
rs:WP_027138598	DNA topoisomerase I [Gaetbulibacter saemankumensis].	25.76	524	297	21	7	504	6	463	2e-13	84.0
rs:WP_007302615	MULTISPECIES: DNA topoisomerase I [Wolbachia].	24.13	460	295	15	80	504	46	486	2e-13	84.0
rs:WP_022551015	DNA topoisomerase 1 [Vibrio nigripulchritudo].	22.69	542	333	18	7	505	6	504	2e-13	84.0
rs:WP_014500347	DNA topoisomerase I [Zymomonas mobilis].	24.91	530	313	23	7	505	4	479	2e-13	84.0
rs:WP_005604172	topoisomerase I [Actinobacillus pleuropneumoniae].	24.51	457	280	19	79	505	84	505	2e-13	84.0
rs:WP_039715725	DNA topoisomerase I [Scytonema millei].	23.65	609	364	18	5	579	3	544	2e-13	84.0
rs:WP_002349461	toprim domain protein, partial [Enterococcus faecium].	38.46	130	68	5	5	129	3	125	2e-13	79.0
tr:U2ITY5_9BACT	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERJ70975.1};	27.91	215	132	6	329	531	1	204	2e-13	82.0
rs:WP_020378945	hypothetical protein [Candidatus Microthrix parvicella].	23.79	559	336	21	1	505	1	523	2e-13	84.0
rs:WP_018660050	DNA topoisomerase I [Bacillus acidiproducens].	25.37	536	311	23	112	607	82	568	2e-13	83.6
rs:WP_034585299	DNA topoisomerase I [Helicobacter magdeburgensis].	24.22	446	289	15	89	505	59	484	2e-13	83.6
rs:WP_038380389	DNA topoisomerase I [Bradyrhizobium elkanii].	23.65	537	329	21	4	505	1	491	2e-13	84.0
rs:WP_028336381	DNA topoisomerase I [Bradyrhizobium elkanii].	23.65	537	329	21	4	505	1	491	2e-13	84.0
rs:WP_018102164	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.08	559	324	21	7	505	15	527	2e-13	84.0
rs:WP_020593538	hypothetical protein [Kiloniella laminariae].	26.37	546	304	23	4	505	1	492	2e-13	84.0
rs:WP_022702085	DNA topoisomerase I [Oceanicaulis alexandrii].	24.96	557	310	25	4	510	1	499	2e-13	84.0
rs:WP_022595650	DNA topoisomerase 1 [Vibrio nigripulchritudo].	22.69	542	333	18	7	505	6	504	2e-13	84.0
rs:WP_004406549	topoisomerase I [Vibrio nigripulchritudo].	22.69	542	333	18	7	505	6	504	2e-13	84.0
rs:WP_047008550	DNA topoisomerase I [Vibrio alginolyticus].	22.92	541	333	20	7	505	6	504	2e-13	84.0
rs:WP_045190613	DNA topoisomerase I [Terrabacter sp. 28].	23.19	552	332	19	7	505	10	522	2e-13	84.0
rs:WP_026751491	DNA topoisomerase I [Sediminibacterium sp. C3].	25.34	438	280	15	89	505	59	470	2e-13	84.0
tr:D4RDK4_ENTFC	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EFF21997.1};	38.46	130	68	5	5	129	3	125	2e-13	78.6
rs:WP_004285114	DNA topoisomerase I [Neisseria weaveri].	25.35	434	268	15	107	505	77	489	2e-13	83.6
rs:WP_002579620	DNA topoisomerase I [Clostridium butyricum].	25.48	526	313	23	7	505	6	479	2e-13	83.6
rs:WP_028767265	DNA topoisomerase I [Shewanella fidelis].	23.97	534	339	20	7	505	6	507	2e-13	84.0
rs:WP_034303584	DNA topoisomerase III, partial [Bacillus sp. 123MFChir2].	31.29	147	98	2	387	530	10	156	2e-13	81.6
rs:WP_009996581	DNA topoisomerase I [Streptomyces clavuligerus].	23.04	560	324	22	7	505	15	528	2e-13	84.0
rs:WP_022592886	DNA topoisomerase 1 [Vibrio nigripulchritudo].	22.69	542	333	18	7	505	6	504	2e-13	84.0
rs:XP_011129487	putative DNA topoisomerase III [Gregarina niphandrodes].	22.00	600	374	19	7	567	8	552	2e-13	84.0
tr:G0UHE0_9LACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.81	528	314	19	7	505	37	510	2e-13	83.6
rs:WP_019236955	DNA topoisomerase I [Wolbachia pipientis].	24.13	460	295	15	80	504	46	486	2e-13	83.6
rs:WP_024788245	MULTISPECIES: DNA topoisomerase I [Lebetimonas].	25.43	519	316	19	7	505	6	473	2e-13	83.6
tr:E4LJS6_9FIRM	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EFR40763.1};	26.62	263	175	11	5	263	23	271	2e-13	80.9
tr:E2Q9N0_STRC2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.04	560	324	22	7	505	29	542	2e-13	84.0
rs:WP_021707641	DNA topoisomerase I [Vibrio alginolyticus].	22.92	541	333	20	7	505	6	504	2e-13	83.6
rs:WP_022792758	DNA topoisomerase I [Marinococcus halotolerans].	24.18	521	321	20	112	599	82	561	2e-13	83.6
rs:WP_008314273	DNA topoisomerase I [Leptolyngbya sp. PCC 6406].	23.99	596	355	21	5	566	3	534	2e-13	84.0
rs:WP_041511027	DNA topoisomerase I [Shewanella sp. cp20].	26.43	420	262	16	107	505	114	507	2e-13	83.6
rs:WP_038388563	DNA topoisomerase I [Bradyrhizobium elkanii].	23.56	539	327	21	4	505	1	491	2e-13	84.0
rs:WP_003009917	DNA topoisomerase I [Leptospira weilii].	22.73	528	326	19	1	505	1	469	2e-13	83.2
rs:WP_012626533	DNA topoisomerase I [Cyanothece sp. PCC 7425].	22.61	544	341	19	84	595	58	553	2e-13	83.6
rs:WP_028155046	DNA topoisomerase I [Bradyrhizobium japonicum].	23.65	537	329	20	4	505	1	491	2e-13	83.6
rs:WP_025011036	DNA topoisomerase I [Shewanella algae].	24.82	419	270	14	107	505	114	507	2e-13	83.6
rs:WP_016876994	DNA topoisomerase I [Chlorogloeopsis fritschii].	24.37	517	304	14	89	566	72	540	2e-13	83.6
tr:F9DSM1_9BACL	SubName: Full=Conjugal transfer nickase/helicase TraI {ECO:0000313|EMBL:EGQ26195.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EGQ26195.1};	29.21	202	130	5	354	548	12	207	2e-13	82.0
rs:WP_019478497	DNA topoisomerase I [Prochlorococcus sp. W8].	25.34	513	298	20	101	579	85	546	2e-13	83.6
rs:WP_005576194	topoisomerase I [Aggregatibacter actinomycetemcomitans].	25.00	440	280	16	88	505	93	504	2e-13	83.6
rs:WP_009495774	DNA topoisomerase I [Campylobacter showae].	25.65	425	268	16	107	505	72	474	2e-13	83.2
rs:WP_029562680	DNA topoisomerase I, partial [Yersinia pestis].	26.19	420	262	16	107	505	100	492	2e-13	83.6
rs:WP_013895222	DNA topoisomerase I [Mesorhizobium opportunistum].	25.23	547	309	24	4	505	1	492	2e-13	83.6
rs:WP_046720326	DNA topoisomerase III, partial [Pseudomonas syringae].	31.87	160	105	3	203	359	1	159	2e-13	79.3
rs:WP_019130607	DNA topoisomerase I [Bacteroidales bacterium ph8].	23.62	525	310	17	7	504	6	466	2e-13	83.6
rs:WP_018271983	DNA topoisomerase I [Bradyrhizobium elkanii].	23.65	537	329	21	4	505	1	491	2e-13	83.6
rs:WP_032824990	topoisomerase I, partial [Oenococcus oeni].	30.48	210	128	7	5	206	3	202	2e-13	79.7
rs:WP_009874718	topoisomerase I [Actinobacillus pleuropneumoniae].	24.73	457	279	19	79	505	84	505	2e-13	83.6
rs:WP_002210622	DNA topoisomerase I [Yersinia pestis].	26.19	420	262	16	107	505	112	504	2e-13	83.6
rs:WP_038958010	DNA topoisomerase I [Bradyrhizobium japonicum].	23.65	537	329	20	4	505	1	491	2e-13	83.6
rs:WP_006300431	DNA topoisomerase I [Aminomonas paucivorans].	22.77	593	346	22	5	568	23	532	2e-13	83.6
rs:WP_039578790	DNA topoisomerase I [Pseudomonas parafulva].	22.76	457	307	13	69	505	74	504	2e-13	83.6
rs:WP_036735187	DNA topoisomerase I, partial [Peptococcaceae bacterium SCADC1_2_3].	24.15	530	324	21	5	505	4	484	2e-13	82.8
sp:TOP1_RICFE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.45	544	325	22	7	510	4	501	2e-13	83.6
rs:WP_025133176	DNA topoisomerase I [Leucobacter sp. PH1c].	23.09	602	344	23	7	550	8	548	2e-13	83.6
rs:WP_035675539	DNA topoisomerase I [Flavobacterium frigidarium].	24.76	529	296	23	7	504	6	463	2e-13	83.6
rs:WP_040981465	DNA topoisomerase I [Mesorhizobium plurifarium].	25.41	551	303	27	4	505	1	492	2e-13	83.6
rs:WP_021904113	DNA topoisomerase [Clostridium sp. CAG:81].	25.06	443	281	16	93	505	63	484	2e-13	83.6
rs:WP_038922768	DNA topoisomerase I [Dickeya dadantii].	25.11	450	267	18	88	505	89	500	3e-13	83.6
rs:WP_022452649	DNA topoisomerase [Prevotella sp. CAG:873].	24.14	522	312	19	7	505	37	497	3e-13	83.6
tr:G7GWG8_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.79	580	342	19	7	535	1	531	3e-13	83.6
rs:WP_022610573	DNA topoisomerase 1 [Vibrio nigripulchritudo].	22.69	542	333	18	7	505	6	504	3e-13	83.6
rs:WP_034363738	DNA topoisomerase I [Helicobacter sp. MIT 01-6451].	23.46	537	320	21	7	505	5	488	3e-13	83.6
rs:WP_009217720	DNA topoisomerase I [Bacteroidetes oral taxon 274].	24.55	444	273	13	88	504	73	481	3e-13	83.6
rs:WP_044854037	DNA topoisomerase I [Amycolatopsis orientalis].	23.83	554	327	22	7	505	22	535	3e-13	83.6
rs:WP_029258706	DNA topoisomerase I [Microbacterium sp. Cr-K29].	22.26	548	334	18	7	505	8	512	3e-13	83.6
rs:WP_013320268	DNA topoisomerase I [Cyanothece sp. PCC 7822].	25.06	451	272	16	97	505	80	506	3e-13	83.6
rs:WP_029267263	DNA topoisomerase I [Microbacterium sp. Cr-K32].	22.26	548	334	18	7	505	8	512	3e-13	83.6
tr:C4U3J9_YERAL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	27.16	416	249	17	88	485	93	472	3e-13	82.8
rs:WP_011734472	DNA topoisomerase I [Pelobacter propionicus].	24.51	559	311	22	7	505	6	513	3e-13	83.6
tr:A0A078MI83_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.34	429	251	16	112	504	82	481	3e-13	83.2
rs:WP_025919080	DNA topoisomerase I [Pectobacterium wasabiae].	24.77	440	281	16	88	505	88	499	3e-13	83.6
rs:WP_039997963	DNA topoisomerase I [Flavonifractor plautii].	22.64	583	346	23	1	553	1	508	3e-13	83.6
tr:A0A075TZU3_9LACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.52	523	325	18	7	504	29	501	3e-13	83.6
tr:G9YGB0_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.44	532	318	20	7	505	61	541	3e-13	83.6
rs:WP_015211400	DNA topoisomerase I [Cylindrospermum stagnale].	24.51	510	306	14	89	566	72	534	3e-13	83.6
tr:L8XD87_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.70	443	295	15	81	505	10	427	3e-13	83.6
rs:WP_021667426	DNA topoisomerase I [Porphyromonas sp. oral taxon 278].	24.07	428	277	12	97	505	69	467	3e-13	83.6
rs:WP_007219031	DNA topoisomerase III [Bacteroides cellulosilyticus].	21.97	569	372	22	4	550	1	519	3e-13	83.2
rs:WP_044877604	DNA topoisomerase I [Paenibacillus sp. IHBB 10380].	24.63	540	302	21	7	504	6	482	3e-13	83.2
rs:WP_026965596	DNA topoisomerase I [Alicyclobacillus pomorum].	24.54	538	305	23	7	504	6	482	3e-13	83.2
rs:WP_016596023	topoisomerase I, partial [Yersinia pestis].	26.19	420	262	16	107	505	103	495	3e-13	83.6
rs:WP_015181243	DNA topoisomerase I [Microcoleus sp. PCC 7113].	25.11	454	284	13	89	505	72	506	3e-13	83.6
rs:WP_038528814	DNA topoisomerase I, partial [Weissella ceti].	23.47	524	326	18	7	505	29	502	3e-13	83.2
rs:WP_005347733	topoisomerase I [Aeromonas veronii].	22.22	540	335	17	7	505	6	501	3e-13	83.6
rs:WP_006492023	DNA topoisomerase 1 [Mesotoga infera].	25.53	521	310	20	7	504	6	471	3e-13	83.2
rs:WP_006275828	DNA topoisomerase I [Cylindrospermopsis raciborskii].	24.95	505	303	16	97	568	80	541	3e-13	83.6
rs:WP_007149281	topoisomerase I [Alcanivorax sp. DG881].	24.21	442	283	15	88	505	98	511	3e-13	83.6
rs:WP_019132545	hypothetical protein [Peptoniphilus obesi].	24.13	518	328	18	7	504	6	478	3e-13	83.2
rs:WP_040346999	DNA topoisomerase I [Anaeroglobus geminatus].	24.44	532	318	20	7	505	58	538	3e-13	83.2
rs:WP_011331169	topoisomerase I [Rhodococcus erythropolis].	24.60	443	278	16	7	425	6	416	3e-13	83.6
rs:WP_038928411	DNA topoisomerase I, partial [Yersinia pestis].	26.19	420	262	16	107	505	79	471	3e-13	83.6
rs:WP_005955940	DNA topoisomerase I [Peptoniphilus harei].	24.05	528	317	21	7	504	6	479	3e-13	83.2
rs:WP_032478146	DNA topoisomerase I [Vibrio cholerae].	24.24	458	298	16	69	505	76	505	3e-13	83.6
tr:A0A0D8IZI5_9FIRM	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KJF39904.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KJF39904.1};	23.91	527	326	19	7	505	5	484	3e-13	83.2
tr:E6Q4P1_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CBI02152.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI02152.1};	26.98	441	273	16	93	504	63	483	3e-13	83.2
rs:WP_014462334	topoisomerase I [Yersinia pestis].	25.60	418	267	15	107	505	48	440	3e-13	83.6
rs:WP_038702721	hypothetical protein, partial [Sphingobacterium sp. ML3W].	24.72	441	278	12	89	504	59	470	3e-13	83.2
rs:WP_002322645	DNA topoisomerase III, partial [Enterococcus faecium].	32.29	192	116	5	385	563	1	191	3e-13	81.6
rs:WP_035575028	hypothetical protein, partial [Holospora undulata].	26.71	453	268	18	97	506	65	496	3e-13	83.2
rs:WP_035544208	hypothetical protein, partial [Holospora elegans].	26.71	453	268	18	97	506	65	496	3e-13	83.2
rs:WP_031080986	DNA topoisomerase I [Streptomyces sp. NRRL WC-3549].	22.98	557	327	22	7	505	15	527	3e-13	83.6
rs:WP_013191215	DNA topoisomerase I [Trichormus azollae].	23.57	594	360	15	5	566	3	534	3e-13	83.6
rs:WP_016998603	DNA topoisomerase I [Staphylococcus lentus].	24.49	535	308	21	7	505	6	480	3e-13	83.2
rs:WP_021229836	topoisomerase I [Aeromonas veronii].	22.22	540	335	17	7	505	6	501	3e-13	83.6
rs:WP_003925181	DNA topoisomerase I [Mycobacterium thermoresistibile].	24.53	477	292	19	80	505	74	533	3e-13	83.6
rs:WP_016261235	topoisomerase I, partial [Yersinia pestis].	26.19	420	262	16	107	505	88	480	3e-13	83.6
rs:WP_043234284	DNA topoisomerase I [Bosea sp. LC85].	25.50	553	309	25	7	510	4	502	3e-13	83.6
rs:WP_042086403	DNA topoisomerase I [alpha proteobacterium Q-1].	25.00	428	279	14	107	505	75	489	3e-13	83.6
rs:WP_043038965	DNA topoisomerase I [Streptococcus equi].	23.03	521	325	18	7	504	30	497	3e-13	83.2
rs:WP_005398276	DNA topoisomerase I [Helcococcus kunzii].	22.87	551	340	16	7	539	6	489	3e-13	83.2
rs:WP_045789265	DNA topoisomerase I [Aeromonas hydrophila].	22.12	538	338	16	7	505	6	501	3e-13	83.6
rs:WP_017850207	DNA topoisomerase I [Leptospira interrogans].	24.67	523	310	20	7	504	5	468	3e-13	83.2
tr:A0A073I7K6_9PORP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.52	567	377	20	4	550	1	519	3e-13	82.8
rs:WP_043532255	DNA topoisomerase I [Halomonas xinjiangensis].	22.57	536	351	17	7	505	6	514	3e-13	83.6
rs:WP_026240474	DNA topoisomerase I [Frankia sp. BCU110501].	23.47	571	326	21	7	510	88	614	3e-13	83.6
rs:WP_043318076	DNA topoisomerase I [Microbulbifer sp. HZ11].	22.74	541	340	17	7	505	6	510	3e-13	83.6
tr:A0A034TJM3_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.55	541	337	19	7	505	6	506	3e-13	83.6
rs:WP_036208086	DNA topoisomerase I [Marinobacter sp. MCTG268].	21.18	543	346	17	7	505	6	510	3e-13	83.6
rs:WP_044478145	DNA topoisomerase III, partial [Peptoclostridium difficile].	27.95	229	147	6	7	233	4	216	3e-13	79.7
rs:WP_036286299	DNA topoisomerase I [Microbacterium sp. MRS-1].	23.09	550	328	17	7	505	13	518	3e-13	83.6
rs:WP_006330915	DNA topoisomerase I [Gordonia rhizosphera].	23.45	550	337	18	7	505	19	535	3e-13	83.6
rs:WP_040197506	DNA topoisomerase I [Candidatus Soleaferrea massiliensis].	23.72	527	323	21	7	504	5	481	3e-13	83.2
rs:WP_045162551	DNA topoisomerase I [Pseudomonas stutzeri].	23.80	437	289	13	88	505	91	502	3e-13	83.2
rs:WP_043808620	DNA topoisomerase I [Rhodococcus triatomae].	25.17	592	336	24	7	550	23	555	3e-13	83.6
rs:WP_027247922	DNA topoisomerase I [Phaeobacter inhibens].	24.87	571	307	26	4	510	1	513	3e-13	83.2
rs:WP_022306116	DNA topoisomerase [Roseburia sp. CAG:380].	23.68	532	315	21	7	504	6	480	3e-13	83.2
rs:WP_022046703	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:18].	25.36	489	306	22	47	504	21	481	3e-13	83.2
rs:WP_026675886	DNA topoisomerase I [Fictibacillus gelatini].	25.45	440	279	15	93	504	63	481	3e-13	83.2
rs:WP_016599731	topoisomerase I, partial [Yersinia pestis].	26.19	420	262	16	107	505	75	467	3e-13	83.2
rs:WP_039081779	DNA topoisomerase I [Gallibacterium anatis].	24.04	441	283	16	88	505	93	504	3e-13	83.2
rs:WP_016594614	topoisomerase I, partial [Yersinia pestis].	26.19	420	262	16	107	505	81	473	3e-13	83.2
rs:WP_000520434	topoisomerase I [Vibrio cholerae].	22.65	543	333	18	7	505	6	505	3e-13	83.2
rs:WP_045282656	DNA topoisomerase I [Shewanella algae].	24.58	419	271	14	107	505	114	507	3e-13	83.2
rs:WP_011021792	DNA topoisomerase [Methanosarcina acetivorans].	25.15	501	308	18	75	548	59	519	3e-13	83.2
rs:WP_021199119	DNA topoisomerase I [Microbacterium maritypicum].	22.26	548	334	18	7	505	8	512	3e-13	83.6
rs:WP_036989641	DNA topoisomerase I [Pseudomonas bauzanensis].	21.24	565	359	17	7	540	6	515	3e-13	83.2
rs:WP_016607025	topoisomerase I [Yersinia pestis].	26.19	420	262	16	107	505	79	471	3e-13	83.2
rs:WP_044736906	DNA topoisomerase I [Geobacillus kaustophilus].	22.95	623	380	22	7	598	6	559	3e-13	83.2
rs:WP_022441506	DNA topoisomerase [Clostridium sp. CAG:768].	23.30	558	347	21	88	607	72	586	3e-13	83.2
rs:WP_036573083	DNA topoisomerase I [Oceanobacillus picturae].	24.71	433	265	16	107	505	77	482	3e-13	83.2
rs:WP_017298517	hypothetical protein [Nodosilinea nodulosa].	25.78	547	301	20	65	566	48	534	3e-13	83.2
rs:WP_016679553	topoisomerase I, partial [Yersinia pestis].	26.19	420	262	16	107	505	83	475	3e-13	83.2
rs:WP_009175240	DNA topoisomerase I [Neisseria sp. oral taxon 014].	24.91	538	310	20	7	505	6	488	3e-13	83.2
rs:WP_025831016	DNA topoisomerase III [Bacteroides stercorirosoris].	20.98	610	410	22	4	590	1	561	3e-13	82.8
rs:WP_009132458	DNA topoisomerase I [Bacteroides oleiciplenus].	23.86	616	372	24	7	585	6	561	3e-13	83.2
rs:WP_019903957	DNA topoisomerase I [Methylobacterium sp. 77].	24.64	560	311	24	4	510	1	502	3e-13	83.2
rs:WP_018392335	DNA topoisomerase I [Bacillus sp. 37MA].	25.71	424	260	15	112	504	82	481	3e-13	83.2
rs:WP_040609953	DNA topoisomerase III, partial [Salimicrobium sp. MJ3].	26.67	225	155	4	383	602	3	222	3e-13	80.9
rs:WP_021902669	DNA topoisomerase [Porphyromonas sp. CAG:1061].	24.32	518	312	20	7	504	6	463	3e-13	83.2
rs:WP_022633521	DNA topoisomerase [Dickeya solani].	25.22	448	269	17	88	505	89	500	3e-13	83.2
rs:WP_013244953	DNA topoisomerase I [Brachyspira pilosicoli].	23.37	569	344	21	7	553	16	514	3e-13	83.2
rs:WP_005773509	DNA topoisomerase I [Bartonella elizabethae].	24.91	550	308	25	4	505	1	493	3e-13	83.2
rs:WP_019231241	hypothetical protein [Rickettsiaceae bacterium Os18].	25.00	540	312	23	7	504	4	492	3e-13	83.2
rs:WP_015045631	topoisomerase I [Simiduia agarivorans].	21.96	469	296	13	69	505	80	510	3e-13	83.2
rs:WP_021720800	DNA topoisomerase [Phascolarctobacterium succinatutens].	23.91	640	364	24	5	601	4	563	3e-13	83.2
rs:WP_034888609	DNA topoisomerase I [Gillisia sp. Hel_I_29].	25.29	522	304	22	7	505	6	464	3e-13	83.2
rs:WP_029791739	DNA topoisomerase I [[Clostridium] mangenotii].	25.28	530	308	22	7	504	6	479	3e-13	83.2
rs:WP_038229594	DNA topoisomerase I [Vibrio sp. ER1A].	22.93	458	304	17	69	505	74	503	3e-13	83.2
rs:WP_013727870	DNA topoisomerase I [Lactobacillus buchneri].	25.77	423	266	16	107	504	98	497	3e-13	83.2
rs:WP_015218159	DNA topoisomerase I [Cyanobacterium aponinum].	23.63	546	330	18	5	505	3	506	3e-13	83.2
rs:WP_015216772	DNA topoisomerase I [Anabaena cylindrica].	23.54	599	354	17	5	566	3	534	3e-13	83.2
rs:WP_021210139	topoisomerase I [Pseudomonas stutzeri].	22.35	537	339	17	7	505	6	502	3e-13	83.2
rs:WP_047093970	DNA topoisomerase I [Erythrobacter marinus].	24.86	543	311	22	7	510	4	488	3e-13	83.2
rs:WP_019119105	DNA topoisomerase I [Brevibacillus massiliensis].	25.71	420	264	14	112	504	82	480	3e-13	83.2
rs:WP_017750624	DNA topoisomerase I [Clostridium tyrobutyricum].	24.11	531	314	22	7	504	6	480	3e-13	83.2
tr:A0A072TH66_MEDTR	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	24.38	525	314	20	36	504	265	762	3e-13	83.2
tr:K5U6E8_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.76	536	334	18	10	505	2	497	3e-13	83.2
rs:WP_026120863	DNA topoisomerase I [Nocardiopsis potens].	23.58	547	335	18	7	505	26	537	3e-13	83.2
tr:V6DHF8_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.39	579	334	25	7	553	19	531	3e-13	83.2
rs:WP_009322477	DNA topoisomerase I [Subdoligranulum sp. 4_3_54A2FAA].	24.20	529	322	19	7	505	5	484	3e-13	83.2
rs:WP_036859382	DNA topoisomerase I, partial [Prevotella disiens].	28.17	213	130	6	331	531	1	202	3e-13	81.6
rs:WP_015153445	DNA topoisomerase I [Chroococcidiopsis thermalis].	23.37	612	367	17	5	579	3	549	3e-13	83.2
rs:WP_014873719	DNA topoisomerase I [Phaeobacter gallaeciensis].	24.87	571	307	26	4	510	1	513	3e-13	83.2
rs:WP_044979619	DNA topoisomerase I [Treponema putidum].	24.81	528	311	22	7	504	24	495	3e-13	83.2
rs:WP_021873408	DNA topoisomerase [Firmicutes bacterium CAG:822].	23.54	531	312	20	7	505	6	474	3e-13	82.8
rs:WP_020278186	DNA topoisomerase I [Geobacillus kaustophilus].	22.83	622	382	21	7	598	6	559	3e-13	82.8
rs:WP_005334892	topoisomerase I [Aeromonas veronii].	22.22	540	335	17	7	505	6	501	3e-13	83.2
rs:WP_039344991	DNA topoisomerase I [Pectobacterium carotovorum].	25.45	440	278	15	88	505	87	498	3e-13	83.2
rs:WP_013919504	DNA topoisomerase I [Paenibacillus mucilaginosus].	23.67	528	328	19	5	504	4	484	3e-13	82.8
rs:WP_002952543	TopA [Campylobacter showae].	25.65	425	268	16	107	505	72	474	3e-13	82.8
rs:WP_014879262	DNA topoisomerase I [Phaeobacter inhibens].	24.87	571	307	26	4	510	1	513	4e-13	83.2
rs:WP_018632196	hypothetical protein [Meganema perideroedes].	24.49	543	321	23	4	510	1	490	4e-13	83.2
rs:WP_040098544	DNA topoisomerase I [Aeromonas australiensis].	22.22	540	335	17	7	505	6	501	4e-13	83.2
tr:K1Y6Q8_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.91	527	323	19	7	506	4	479	4e-13	83.2
tr:B5GPN9_STRC2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.04	560	324	22	7	505	1	514	4e-13	83.2
rs:WP_033292924	DNA topoisomerase I [Amycolatopsis jejuensis].	23.60	555	329	19	7	505	22	537	4e-13	83.2
rs:WP_006955122	topoisomerase I [Idiomarina baltica].	22.51	542	335	18	7	505	6	505	4e-13	83.2
tr:M2X4Y3_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.17	592	336	24	7	550	1	533	4e-13	83.2
rs:WP_045836775	DNA topoisomerase I [Hyphomicrobium sp. 99].	25.05	491	271	20	80	505	46	504	4e-13	83.2
rs:WP_027404227	DNA topoisomerase I [Aphanizomenon flos-aquae].	23.88	448	284	16	91	505	66	489	4e-13	82.8
rs:WP_018613933	hypothetical protein [Segetibacter koreensis].	24.57	521	313	20	7	504	6	469	4e-13	83.2
rs:WP_038880283	DNA topoisomerase I [Cronobacter sakazakii].	24.83	435	287	15	88	505	17	428	4e-13	83.2
rs:WP_026570374	MULTISPECIES: DNA topoisomerase I [Bacillaceae].	26.00	423	261	15	112	505	82	481	4e-13	82.8
rs:WP_019490681	DNA topoisomerase I [Calothrix sp. PCC 7103].	25.10	514	298	15	89	566	72	534	4e-13	83.2
rs:WP_017829062	DNA topoisomerase I [Microbacterium sp. UCD-TDU].	22.30	547	335	18	7	505	8	512	4e-13	83.2
rs:WP_002608927	DNA topoisomerase I [[Clostridium] innocuum].	25.27	546	332	24	80	593	50	551	4e-13	82.8
rs:WP_009589046	MULTISPECIES: DNA topoisomerase I [Clostridiales].	25.27	546	332	24	80	593	50	551	4e-13	82.8
rs:XP_010112124	DNA topoisomerase 1 [Morus notabilis].	24.34	530	295	21	47	505	369	863	4e-13	83.2
rs:WP_045803759	DNA topoisomerase I [Rickettsia endosymbiont of Ixodes pacificus].	24.36	546	323	23	7	510	4	501	4e-13	82.8
rs:WP_044601245	hypothetical protein [Candidatus Babela massiliensis].	25.39	579	334	25	7	553	6	518	4e-13	82.8
tr:H5X247_9PSEU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.29	560	333	21	7	510	78	602	4e-13	83.2
rs:WP_036519729	DNA topoisomerase I [Nitrincola sp. A-D6].	23.91	460	280	16	88	512	98	522	4e-13	83.2
rs:WP_018696524	DNA topoisomerase I [Alistipes onderdonkii].	23.48	541	292	19	7	504	6	467	4e-13	82.8
rs:WP_018338119	DNA topoisomerase I [Butyricimonas synergistica].	23.23	508	322	14	7	500	6	459	4e-13	82.8
rs:WP_014296545	DNA topoisomerase I [Marinitoga piezophila].	24.64	560	324	19	7	544	9	492	4e-13	82.8
rs:WP_032134845	DNA topoisomerase I [Alistipes sp. AL-1].	23.48	541	292	19	7	504	6	467	4e-13	82.8
tr:A0A072TFG8_MEDTR	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	24.38	525	314	20	36	504	265	762	4e-13	83.2
rs:WP_001961705	DNA topoisomerase I [Vibrio cholerae].	24.13	460	296	16	69	505	76	505	4e-13	83.2
rs:WP_029276016	DNA topoisomerase I [Carnobacterium jeotgali].	23.45	533	327	19	1	504	1	481	4e-13	82.8
rs:WP_023508056	DNA topoisomerase 1 [Rickettsia monacensis].	24.18	546	324	23	7	510	4	501	4e-13	82.8
rs:WP_008817324	MULTISPECIES: DNA topoisomerase I [Erysipelotrichaceae].	25.27	546	332	24	80	593	50	551	4e-13	82.8
rs:WP_036587972	DNA topoisomerase I [Paenibacillus sophorae].	23.67	528	321	21	7	504	6	481	4e-13	82.8
rs:WP_023133708	DNA topoisomerase I [Rothia aeria].	24.38	603	348	21	7	566	12	549	4e-13	83.2
tr:A0A0D6AKL8_9CHRO	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:BAQ63366.1};	23.91	548	326	18	5	505	3	506	4e-13	83.2
rs:WP_007310208	DNA topoisomerase I [Crocosphaera watsonii].	25.11	470	280	17	91	512	45	490	4e-13	83.2
rs:WP_037478091	hypothetical protein, partial [Sphingobium sp. ba1].	25.38	524	313	22	7	505	4	474	4e-13	83.2
rs:WP_032820860	topoisomerase I, partial [Oenococcus oeni].	29.05	241	153	9	279	508	6	239	4e-13	79.7
rs:WP_035148559	DNA topoisomerase I [Clostridium tetanomorphum].	24.24	528	317	21	7	504	6	480	4e-13	82.8
rs:WP_036851281	DNA topoisomerase I [Porphyromonas cangingivalis].	23.61	521	312	17	7	504	6	463	4e-13	82.8
rs:WP_027284170	DNA topoisomerase I [Rubritepida flocculans].	24.31	543	312	22	7	505	5	492	4e-13	83.2
rs:WP_038671950	DNA topoisomerase I [Ruminococcus bicirculans].	25.56	450	277	17	89	505	58	482	4e-13	82.8
rs:WP_026466076	DNA topoisomerase I [Aerococcus urinaeequi].	22.74	519	330	17	7	504	7	475	4e-13	82.8
rs:WP_034675695	DNA topoisomerase I [Bacillus niacini].	25.82	426	258	14	112	504	82	482	4e-13	82.8
rs:XP_011006669	PREDICTED: uncharacterized protein LOC105112620 [Populus euphratica].	25.24	511	303	21	47	505	340	823	4e-13	83.2
rs:WP_005622925	topoisomerase I [Actinobacillus ureae].	24.67	454	283	18	79	505	84	505	4e-13	83.2
rs:WP_005597038	topoisomerase I [Actinobacillus pleuropneumoniae].	25.38	457	276	19	79	505	84	505	4e-13	83.2
rs:WP_010687784	DNA topoisomerase I [Leuconostoc gelidum].	24.01	529	314	22	7	504	29	500	4e-13	82.8
tr:A0A061JG33_9RICK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.48	457	264	19	97	506	65	496	4e-13	83.2
rs:WP_021616225	DNA topoisomerase I [Aggregatibacter sp. oral taxon 458].	22.73	550	331	19	3	505	2	504	4e-13	82.8
rs:WP_039455829	DNA topoisomerase I [endosymbiont of Acanthamoeba sp. UWC36].	25.70	533	314	23	7	504	4	489	4e-13	82.8
rs:WP_040580726	DNA topoisomerase I [Porphyromonas endodontalis].	23.59	551	334	16	7	530	8	498	4e-13	82.8
rs:WP_022488428	DNA topoisomerase [Clostridium sp. CAG:914].	23.27	623	368	26	3	595	2	544	4e-13	82.8
rs:WP_029509338	DNA topoisomerase I [Leuconostoc lactis].	23.53	527	319	22	7	504	34	505	4e-13	82.8
rs:WP_005362158	topoisomerase I [Aeromonas veronii].	22.22	540	335	17	7	505	6	501	4e-13	82.8
rs:WP_013280745	DNA topoisomerase I [Butyrivibrio proteoclasticus].	25.34	442	278	18	93	504	71	490	4e-13	82.8
rs:WP_016916640	DNA topoisomerase I [Rickettsia honei].	24.18	546	324	23	7	510	4	501	4e-13	82.8
rs:WP_012231710	DNA topoisomerase I [Bartonella tribocorum].	24.55	550	310	24	4	505	1	493	4e-13	82.8
rs:WP_023198152	DNA topoisomerase III, partial [Salmonella enterica].	24.68	231	161	5	8	234	5	226	4e-13	79.3
rs:WP_045492721	DNA topoisomerase I [Vibrio sp. 151112A].	22.74	541	334	20	7	505	6	504	4e-13	82.8
rs:WP_025342644	DNA topoisomerase I [Mannheimia varigena].	24.38	447	293	15	79	505	83	504	4e-13	82.8
rs:WP_006770208	DNA topoisomerase I [Corynebacterium efficiens].	23.86	528	311	23	40	505	31	529	4e-13	83.2
rs:WP_046439302	DNA topoisomerase I [Ruminococcus sp. N15.MGS-57].	25.56	450	277	17	89	505	58	482	4e-13	82.8
rs:WP_045685654	DNA topoisomerase I [Martelella endophytica].	24.05	553	327	23	4	510	1	506	4e-13	82.8
rs:WP_017601719	DNA topoisomerase I [Nocardiopsis lucentensis].	23.19	552	326	21	7	505	26	532	4e-13	82.8
rs:WP_024790332	DNA topoisomerase I [Lebetimonas sp. JH292].	24.52	518	322	17	7	505	6	473	4e-13	82.8
rs:WP_027460080	DNA topoisomerase I [Deinococcus murrayi].	24.24	627	349	26	5	579	4	556	4e-13	82.8
tr:A0A087NAY7_9SPHN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.38	524	313	22	7	505	4	474	4e-13	82.8
rs:WP_038704262	DNA topoisomerase I [Planococcus sp. PAMC 21323].	24.39	529	314	20	7	504	6	479	4e-13	82.8
rs:WP_035903139	DNA topoisomerase I [Fusobacterium necrophorum].	22.77	527	330	20	1	504	1	473	4e-13	82.8
rs:WP_002333472	hypothetical protein, partial [Enterococcus faecium].	24.83	286	203	7	147	428	2	279	4e-13	80.1
gpu:CP011832_1130	DNA topoisomerase 1 [Geobacillus sp. 12AMOR1]	23.11	623	379	22	7	598	6	559	4e-13	82.8
rs:WP_004052455	DNA topoisomerase I [Eubacterium plexicaudatum].	25.28	451	269	18	93	505	63	483	4e-13	82.8
rs:WP_035720077	DNA topoisomerase I [Francisella sp. W12-1067].	24.35	616	357	25	7	581	6	553	4e-13	82.8
rs:WP_018625461	topoisomerase I [Kangiella aquimarina].	24.40	459	297	17	69	505	80	510	4e-13	82.8
rs:WP_004005452	DNA topoisomerase I [Rothia dentocariosa].	23.97	605	348	22	7	566	12	549	4e-13	82.8
tr:W6SQD0_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.86	608	347	20	5	566	3	534	4e-13	82.8
rs:WP_019271676	DNA topoisomerase I [Neisseria sicca].	24.63	540	309	21	7	505	6	488	4e-13	82.8
rs:WP_015840249	topoisomerase I [Pectobacterium carotovorum].	25.45	440	278	17	88	505	88	499	4e-13	82.8
rs:WP_025247671	DNA topoisomerase I [Mannheimia varigena].	24.38	447	293	15	79	505	83	504	4e-13	82.8
rs:WP_016587519	topoisomerase I, partial [Yersinia pestis].	25.60	418	267	15	107	505	19	411	4e-13	82.8
rs:WP_009399149	DNA topoisomerase I [Pseudomonas putida].	24.79	476	299	15	97	555	75	508	4e-13	82.4
rs:WP_045422306	DNA topoisomerase I [Vibrio jasicida].	22.92	541	333	20	7	505	6	504	4e-13	82.8
rs:WP_033191919	DNA topoisomerase I [Fervidobacterium islandicum].	25.55	595	339	24	7	583	41	549	4e-13	82.8
rs:WP_009736670	DNA topoisomerase I [Bradyrhizobiaceae bacterium SG-6C].	24.54	538	318	23	7	505	4	492	4e-13	82.8
rs:XP_011094464	PREDICTED: uncharacterized protein LOC105174160 isoform X1 [Sesamum indicum].	26.06	518	294	23	47	505	370	857	4e-13	83.2
tr:A0A094RFZ6_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KGA03558.1};	24.41	553	328	20	3	505	2	514	4e-13	82.8
tr:T2JG30_CROWT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.11	470	280	17	91	512	74	519	4e-13	82.8
rs:WP_015090086	DNA topoisomerase I [Bdellovibrio bacteriovorus].	23.59	585	353	18	3	550	10	537	4e-13	82.8
rs:WP_024596730	DNA topoisomerase I, partial [Pseudoalteromonas haloplanktis].	23.46	439	286	14	88	504	96	506	4e-13	82.4
rs:WP_014499986	topoisomerase I [Buchnera aphidicola].	23.08	572	349	19	3	544	2	512	4e-13	82.8
rs:WP_013678931	DNA topoisomerase [Thermoproteus uzoniensis].	22.28	561	373	19	7	548	3	519	4e-13	82.4
rs:WP_007305008	DNA topoisomerase I [Crocosphaera watsonii].	25.11	470	280	17	91	512	74	519	4e-13	82.8
rs:WP_028865557	DNA topoisomerase I [Psychromonas aquimarina].	23.02	556	352	22	69	598	76	581	4e-13	82.8
rs:WP_014217896	DNA topoisomerase I [Niastella koreensis].	23.90	544	324	21	7	515	6	494	5e-13	82.8
rs:WP_023445655	topoisomerase I [Pseudomonas chloritidismutans].	22.16	537	340	18	7	505	6	502	5e-13	82.8
rs:WP_015863217	DNA topoisomerase I [Desulfovibrio magneticus].	23.66	524	324	18	7	505	6	478	5e-13	82.8
rs:WP_024603564	DNA topoisomerase I, partial [Pseudoalteromonas haloplanktis].	23.46	439	286	14	88	504	96	506	5e-13	82.4
rs:WP_011503433	DNA topoisomerase I [Rhodopseudomonas palustris].	24.72	534	322	20	7	505	4	492	5e-13	82.8
rs:WP_019286527	hypothetical protein, partial [Rhodococcus sp. R04].	23.20	543	339	18	7	504	10	519	5e-13	82.4
tr:C3JAB5_9PORP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.59	551	334	16	7	530	57	547	5e-13	82.8
rs:WP_012149421	DNA topoisomerase I [Rickettsia akari].	24.36	546	323	23	7	510	4	501	5e-13	82.8
rs:WP_024098242	DNA topoisomerase I [Phaeobacter gallaeciensis].	24.87	571	307	26	4	510	1	513	5e-13	82.8
rs:WP_008041237	topoisomerase I [Reinekea blandensis].	24.16	476	302	19	46	504	28	461	5e-13	82.4
tr:A0A072VD72_MEDTR	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	24.66	511	307	19	36	495	265	748	5e-13	82.8
rs:WP_014371423	DNA topoisomerase I [Paenibacillus mucilaginosus].	23.63	529	328	19	5	504	4	485	5e-13	82.4
tr:A0A023DYM8_9RICK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.48	457	264	19	97	506	65	496	5e-13	82.8
rs:WP_045434151	hypothetical protein [bacterium UASB270].	24.59	549	310	22	7	505	6	500	5e-13	82.8
rs:WP_008220403	topoisomerase I [Rheinheimera nanhaiensis].	25.06	443	277	16	88	505	82	494	5e-13	82.8
rs:WP_019808041	DNA topoisomerase I [Osedax symbiont Rs1].	24.94	441	275	19	99	512	108	519	5e-13	82.8
rs:WP_016268924	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.00	524	307	19	7	504	6	469	5e-13	82.8
rs:WP_035825898	DNA topoisomerase I [Crocosphaera watsonii].	25.11	470	280	17	91	512	74	519	5e-13	82.8
rs:WP_039083418	DNA topoisomerase I [Gallibacterium anatis].	24.04	441	283	16	88	505	93	504	5e-13	82.8
rs:WP_031892887	DNA topoisomerase III, partial [Staphylococcus aureus].	29.94	177	114	5	7	181	5	173	5e-13	78.6
rs:WP_017532550	DNA topoisomerase I [Wolbachia endosymbiont of Diaphorina citri].	24.13	460	295	15	80	504	46	486	5e-13	82.8
rs:WP_028411437	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.70	421	267	13	112	504	82	480	5e-13	82.4
rs:WP_007724946	DNA topoisomerase I [Carnobacterium sp. AT7].	23.45	533	327	19	1	504	1	481	5e-13	82.4
rs:WP_041014252	MULTISPECIES: DNA topoisomerase I [Pseudomonas stutzeri group].	21.97	537	341	18	7	505	6	502	5e-13	82.8
rs:WP_012097495	DNA topoisomerase I [Anaeromyxobacter sp. Fw109-5].	23.26	645	383	26	7	605	41	619	5e-13	82.8
rs:WP_011706893	DNA topoisomerase I [Aeromonas hydrophila].	21.93	538	339	16	7	505	6	501	5e-13	82.8
rs:WP_025550636	DNA topoisomerase I [Vibrio parahaemolyticus].	22.98	544	329	21	7	505	6	504	5e-13	82.8
tr:A0A072VE62_MEDTR	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	24.66	511	307	19	36	495	265	748	5e-13	82.8
rs:WP_010196278	topoisomerase I [Psychrobacter sp. PAMC 21119].	23.74	438	292	13	88	505	104	519	5e-13	82.8
rs:WP_005268646	DNA topoisomerase I [Arthrobacter crystallopoietes].	24.58	541	321	19	7	500	14	514	5e-13	82.8
rs:WP_019181621	DNA topoisomerase I [Microbacterium yannicii].	23.12	545	338	20	7	505	12	521	5e-13	82.8
rs:WP_025306605	DNA topoisomerase I [Thermocrinis ruber].	25.49	463	285	19	91	544	58	469	5e-13	82.0
tr:C6M8I2_NEISI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.63	540	309	21	7	505	28	510	5e-13	82.8
rs:WP_004622029	DNA topoisomerase I [[Clostridium] papyrosolvens].	23.79	538	316	20	7	504	6	489	5e-13	82.4
rs:WP_029498225	DNA topoisomerase I [Kurthia huakuii].	26.93	427	253	16	112	504	82	483	5e-13	82.4
tr:E6YZ97_BARSR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.84	459	265	21	97	505	65	493	5e-13	82.8
rs:WP_025908998	DNA topoisomerase I [Bacillus flexus].	24.09	523	318	18	112	599	82	560	5e-13	82.4
rs:WP_025217263	DNA topoisomerase I [Mannheimia varigena].	24.44	450	289	16	79	505	83	504	5e-13	82.8
rs:WP_022481595	DNA topoisomerase [Clostridium sp. CAG:729].	22.70	555	354	19	88	607	80	594	5e-13	82.4
tr:F3CCA9_PSESG	SubName: Full=Topoisomerase {ECO:0000313|EMBL:EGH16901.1}; Flags: Fragment;	24.62	264	192	5	101	361	2	261	5e-13	79.7
rs:WP_019138070	DNA topoisomerase I [Peptoniphilus timonensis].	23.53	527	322	19	7	504	6	480	5e-13	82.4
rs:WP_013075487	DNA topoisomerase I [Kyrpidia tusciae].	25.99	431	259	18	107	504	77	480	5e-13	82.4
tr:W1DXM5_KLEPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.63	189	125	5	198	379	15	202	5e-13	79.0
rs:WP_034406896	DNA topoisomerase I [Deinococcus sp. RL].	24.52	628	346	27	5	579	4	556	5e-13	82.8
rs:WP_027146697	DNA topoisomerase I [Mesorhizobium sp. WSM3626].	24.25	536	328	20	4	505	1	492	5e-13	82.8
rs:WP_042223781	DNA topoisomerase I [Oceanobacillus manasiensis].	24.01	429	273	14	107	505	77	482	5e-13	82.4
rs:WP_019103996	DNA topoisomerase I, partial [Chromobacterium sp. C-61].	24.10	502	318	17	43	510	15	487	5e-13	82.4
rs:WP_035268307	DNA topoisomerase I [Desulfitibacter alkalitolerans].	24.11	618	371	25	7	596	6	553	5e-13	82.4
rs:WP_044731729	DNA topoisomerase I [Geobacillus kaustophilus].	22.95	623	380	22	7	598	6	559	5e-13	82.4
rs:WP_043039794	DNA topoisomerase I [Vibrio parahaemolyticus].	22.69	542	333	20	7	505	6	504	5e-13	82.8
rs:WP_020857203	DNA topoisomerase I [SAR86 cluster bacterium SAR86A].	24.64	556	327	21	3	512	2	511	5e-13	82.8
rs:WP_044263883	DNA topoisomerase I [Candidatus Bacteroides timonensis].	24.81	520	313	19	7	504	6	469	5e-13	82.4
rs:WP_006828261	DNA topoisomerase I [Planococcus antarcticus].	24.11	531	313	21	7	504	6	479	5e-13	82.4
rs:WP_014364595	DNA topoisomerase I [Rickettsia philipii].	24.18	546	324	23	7	510	4	501	5e-13	82.4
rs:WP_003350210	DNA topoisomerase I [Bacillus methanolicus].	24.82	423	264	13	112	504	82	480	5e-13	82.4
rs:WP_010320022	topoisomerase I [Vibrio ordalii].	23.80	458	300	16	69	505	75	504	5e-13	82.8
rs:WP_021091905	DNA topoisomerase I [Campylobacter concisus].	25.41	425	269	16	107	505	72	474	5e-13	82.4
rs:XP_011094466	PREDICTED: uncharacterized protein LOC105174160 isoform X2 [Sesamum indicum].	26.06	518	294	23	47	505	368	855	5e-13	82.8
rs:WP_008142805	DNA topoisomerase I [Bacteroides coprophilus].	22.78	518	322	18	7	504	6	465	5e-13	82.4
rs:WP_008592235	DNA topoisomerase I [Leptospira licerasiae].	22.41	531	322	19	7	504	5	478	5e-13	82.4
rs:WP_028246918	DNA topoisomerase I [Pseudobutyrivibrio ruminis].	24.40	496	303	23	47	504	21	482	5e-13	82.4
rs:WP_027872607	DNA topoisomerase I [Spongiibacter marinus].	22.61	460	305	14	62	505	87	511	5e-13	82.8
rs:WP_003442199	DNA topoisomerase I [Clostridium pasteurianum].	24.36	550	321	22	7	517	6	499	5e-13	82.4
rs:WP_006959504	DNA topoisomerase I [Sphingobium japonicum].	25.00	524	315	21	7	505	4	474	5e-13	82.4
rs:WP_012150651	DNA topoisomerase I [Rickettsia rickettsii].	24.18	546	324	23	7	510	4	501	5e-13	82.4
rs:WP_028526255	DNA topoisomerase I [Runella limosa].	23.34	527	311	18	7	505	6	467	5e-13	82.4
rs:WP_009084356	DNA topoisomerase I [Streptomyces sp. AA4].	23.60	555	327	20	7	505	22	535	5e-13	82.8
rs:WP_022147116	DNA topoisomerase [Bacteroides sp. CAG:709].	25.80	438	277	18	89	506	65	474	5e-13	82.4
rs:WP_038866755	MULTISPECIES: DNA topoisomerase I [Vibrio].	23.11	541	332	20	7	505	6	504	5e-13	82.4
rs:WP_046863367	DNA topoisomerase I [Microvirga sp. JC119].	23.77	551	327	23	4	510	1	502	5e-13	82.8
rs:WP_004816257	DNA topoisomerase I [Anaerococcus hydrogenalis].	23.39	573	350	24	7	561	6	507	5e-13	82.4
rs:WP_016762302	DNA topoisomerase I [Leptospira kirschneri].	24.47	523	311	20	7	504	5	468	5e-13	82.0
rs:WP_004766649	DNA topoisomerase I [Leptospira kirschneri].	24.47	523	311	20	7	504	5	468	5e-13	82.0
rs:WP_002856321	DNA topoisomerase I [Micrococcus luteus].	23.31	562	329	22	7	505	19	541	5e-13	82.8
rs:WP_022278168	DNA topoisomerase [Bacteroides coprophilus CAG:333].	22.78	518	322	18	7	504	6	465	5e-13	82.4
rs:WP_028531204	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	25.00	440	283	15	92	504	62	481	5e-13	82.4
rs:WP_029653650	DNA topoisomerase I [Marinobacter daepoensis].	21.98	546	338	18	7	505	6	510	5e-13	82.4
rs:WP_021776257	glutamyl-tRNA amidotransferase subunit A Glu-ADT subunit A protein [alpha proteobacterium RS24].	23.59	551	322	22	7	510	4	502	5e-13	82.4
rs:WP_033899618	DNA topoisomerase I [Lactococcus lactis].	25.10	522	313	23	7	504	29	496	5e-13	82.4
rs:WP_017311325	DNA topoisomerase I [Fischerella sp. PCC 9339].	24.76	513	295	16	95	566	78	540	5e-13	82.4
rs:WP_035721465	DNA topoisomerase I [Gracilibacillus boraciitolerans].	23.86	528	323	20	7	505	6	483	5e-13	82.4
rs:WP_019404447	DNA topoisomerase I [Chelatococcus sp. GW1].	24.95	541	317	22	4	505	1	491	5e-13	82.4
rs:WP_040929149	DNA topoisomerase I [Nosocomiicoccus sp. NP2].	25.35	426	266	16	107	504	77	478	5e-13	82.4
rs:WP_003302513	DNA topoisomerase I subunit omega, partial [Pseudomonas stutzeri].	22.37	456	310	13	69	505	31	461	5e-13	82.4
rs:WP_012262322	DNA topoisomerase I [Rickettsia rickettsii].	24.18	546	324	23	7	510	4	501	5e-13	82.4
rs:WP_009312695	MULTISPECIES: DNA topoisomerase I [Neisseria].	24.63	540	309	21	7	505	6	488	5e-13	82.4
rs:WP_024944133	DNA topoisomerase I [Aeromonas hydrophila].	21.93	538	339	16	7	505	6	501	5e-13	82.4
rs:WP_013461927	DNA topoisomerase I [Candidatus Liberibacter solanacearum].	25.73	548	305	26	4	505	1	492	6e-13	82.4
rs:WP_017322230	DNA topoisomerase I [cyanobacterium PCC 7702].	24.12	510	301	15	95	566	78	539	6e-13	82.4
rs:WP_030199619	DNA topoisomerase I [Streptomyces sp. NRRL S-87].	23.16	557	324	21	7	505	15	525	6e-13	82.4
gp:CP004146_894	DNA topoisomerase I [Borrelia hermsii YOR]	23.04	599	353	23	7	561	7	541	6e-13	82.0
rs:WP_044800504	DNA topoisomerase I [Aeromonas hydrophila].	21.93	538	339	16	7	505	6	501	6e-13	82.4
rs:WP_043160059	DNA topoisomerase I [Aeromonas hydrophila].	21.93	538	339	16	7	505	6	501	6e-13	82.4
rs:WP_007219376	DNA topoisomerase I [Bacteroides cellulosilyticus].	24.76	521	314	19	7	505	6	470	6e-13	82.4
rs:WP_035925040	DNA topoisomerase I [Kocuria polaris].	24.51	567	310	22	7	505	16	532	6e-13	82.4
rs:WP_024061638	DNA topoisomerase [Veillonella dispar].	24.57	525	317	22	7	504	76	548	6e-13	82.4
rs:WP_047256160	DNA topoisomerase I [Moellerella wisconsensis].	25.82	457	277	20	88	513	86	511	6e-13	82.4
rs:WP_023582278	DNA topoisomerase I [Proteus hauseri].	23.28	537	330	20	7	505	6	498	6e-13	82.4
rs:WP_045527759	DNA topoisomerase I [Aeromonas hydrophila].	21.93	538	339	16	7	505	6	501	6e-13	82.4
rs:WP_028329924	DNA topoisomerase I [Brachyspira alvinipulli].	23.82	571	339	22	7	553	32	530	6e-13	82.4
rs:WP_010282476	DNA topoisomerase I [Bacillus timonensis].	25.30	419	267	15	112	504	82	480	6e-13	82.4
rs:WP_022989227	topoisomerase I [Marinobacter sp. ES-1].	21.72	548	337	18	7	505	6	510	6e-13	82.4
rs:WP_014908638	DNA topoisomerase I [Nocardiopsis alba].	24.41	549	329	22	7	505	26	538	6e-13	82.4
rs:WP_041216392	DNA topoisomerase I [Aeromonas hydrophila].	21.93	538	339	16	7	505	6	501	6e-13	82.4
rs:WP_007226908	topoisomerase I [marine gamma proteobacterium HTCC2143].	22.35	452	314	13	69	505	78	507	6e-13	82.4
rs:WP_035193594	DNA topoisomerase I [Bacillus azotoformans].	24.76	424	265	15	112	504	82	482	6e-13	82.4
tr:A0A061PJJ8_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.55	541	336	19	7	505	6	505	6e-13	82.4
rs:WP_036848414	DNA topoisomerase I [Porphyromonas cangingivalis].	23.95	522	309	18	7	504	6	463	6e-13	82.4
tr:I2NWJ9_NEISI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.63	540	309	21	7	505	28	510	6e-13	82.4
rs:WP_035237944	DNA topoisomerase, partial [Acidobacteriaceae bacterium URHE0068].	23.90	569	327	20	3	510	2	525	6e-13	82.4
rs:WP_035486060	DNA topoisomerase I, partial [Alicyclobacillus contaminans].	24.10	527	321	21	7	504	6	482	6e-13	82.4
rs:WP_029505861	DNA topoisomerase I [Lachnospiraceae bacterium AC2012].	24.29	527	320	25	7	504	6	482	6e-13	82.4
rs:WP_016351565	DNA topoisomerase I subunit omega [Aeromonas hydrophila].	21.93	538	339	16	7	505	6	501	6e-13	82.4
rs:WP_004778509	DNA topoisomerase I [Leptospira kirschneri].	24.76	529	314	20	1	505	1	469	6e-13	82.0
rs:WP_010703721	DNA topoisomerase I [Bartonella schoenbuchensis].	24.84	459	265	21	97	505	65	493	6e-13	82.4
rs:WP_008497955	DNA topoisomerase I [Planococcus halocryophilus].	24.29	531	312	21	7	504	6	479	6e-13	82.0
rs:WP_034994474	DNA topoisomerase I [Lactobacillus vini].	23.90	523	323	20	7	505	18	489	6e-13	82.4
rs:WP_025251782	DNA topoisomerase I [Corynebacterium vitaeruminis].	25.05	471	284	19	86	505	75	527	6e-13	82.4
rs:WP_014570604	DNA topoisomerase 1 [Lactococcus lactis].	25.43	527	305	24	7	504	29	496	6e-13	82.4
rs:WP_029827738	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	6e-13	82.0
rs:WP_018132573	hypothetical protein [Effusibacillus pohliae].	23.58	530	322	20	7	504	6	484	6e-13	82.4
rs:WP_021444488	topoisomerase I [Pseudomonas sp. EGD-AK9].	22.76	536	339	22	7	505	6	503	6e-13	82.4
rs:WP_015022536	DNA topoisomerase I [Bifidobacterium asteroides].	22.60	553	332	21	7	505	8	518	6e-13	82.4
rs:WP_042145160	DNA topoisomerase I [Pseudoalteromonas sp. '520P1 No. 412'].	22.78	553	322	22	7	505	6	507	6e-13	82.4
rs:WP_022286871	DNA topoisomerase [Ruminococcus sp. CAG:57].	25.56	450	277	17	89	505	58	482	6e-13	82.0
rs:WP_002245394	DNA topoisomerase I [Neisseria meningitidis].	24.53	534	317	21	7	505	6	488	6e-13	82.4
rs:WP_025630849	DNA topoisomerase I [Vibrio parahaemolyticus].	22.69	542	333	20	7	505	6	504	6e-13	82.4
rs:WP_002437344	topoisomerase I [Escherichia hermannii].	23.86	461	307	15	64	505	66	501	6e-13	82.4
rs:WP_039991082	DNA topoisomerase I [Fusobacterium gonidiaformans].	23.24	525	330	20	1	504	1	473	6e-13	82.4
rs:WP_017864498	DNA topoisomerase I [Lactococcus lactis].	25.10	522	313	23	7	504	29	496	6e-13	82.0
rs:WP_034844101	DNA topoisomerase I, partial [Inquilinus limosus].	24.64	552	315	22	1	505	1	498	6e-13	82.4
tr:S9SZJ9_PAEAL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.43	438	288	14	92	504	36	455	6e-13	82.0
rs:WP_023780594	DNA topoisomerase I [Mesorhizobium sp. LNHC221B00].	25.05	547	310	24	4	505	1	492	6e-13	82.4
rs:WP_033237235	topoisomerase I [Rhodococcus rhodochrous].	24.39	451	269	18	7	425	6	416	6e-13	82.4
rs:WP_022210546	MULTISPECIES: DNA topoisomerase [Bacteroides].	24.76	521	314	19	7	505	6	470	6e-13	82.4
rs:WP_043865257	DNA topoisomerase I [Enterobacter aerogenes].	23.86	461	307	15	64	505	66	501	6e-13	82.4
rs:WP_013792006	topoisomerase I [Pseudomonas fulva].	22.37	532	346	17	7	505	6	503	6e-13	82.4
rs:WP_008675116	DNA topoisomerase III [Bacteroides sp. 9_1_42FAA].	21.65	568	375	21	4	550	1	519	6e-13	82.0
tr:S7VT95_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	28.17	426	246	17	106	505	76	467	6e-13	82.4
rs:WP_015415282	DNA topoisomerase 1 [Desulfovibrio piezophilus].	25.33	533	309	23	7	505	6	483	6e-13	82.4
rs:WP_034435230	DNA topoisomerase I [Candidatus Contendobacter odensis].	25.09	558	304	24	7	505	6	508	6e-13	82.4
rs:WP_017950657	MULTISPECIES: hypothetical protein [Marinimicrobia].	25.00	484	304	17	43	500	27	477	6e-13	82.0
rs:WP_028392863	DNA topoisomerase I [Bacillus sp. FJAT-14515].	24.88	418	270	13	112	504	82	480	6e-13	82.0
tr:G6EY22_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.74	481	289	21	81	510	6	464	6e-13	82.4
rs:WP_037176028	DNA topoisomerase I [Rhodococcus fascians].	25.34	592	335	24	7	550	19	551	6e-13	82.4
rs:WP_029304161	DNA topoisomerase I [Aeromonas hydrophila].	21.93	538	339	16	7	505	6	501	6e-13	82.4
rs:WP_017443149	DNA topoisomerase I [Candidatus Rickettsia gravesii].	24.82	544	323	23	7	510	4	501	6e-13	82.4
rs:WP_042803046	DNA topoisomerase I [Mannheimia haemolytica].	24.06	453	287	17	79	505	83	504	6e-13	82.4
rs:WP_009302711	DNA topoisomerase I [Desulfovibrio sp. 6_1_46AFAA].	26.20	439	279	15	91	505	61	478	6e-13	82.0
rs:WP_029678237	DNA topoisomerase I [Bifidobacterium sp. 7101].	22.78	553	331	21	7	505	8	518	6e-13	82.4
rs:WP_016464462	DNA topoisomerase I [Microbacterium sp. oral taxon 186].	22.91	550	329	18	7	505	13	518	6e-13	82.4
rs:WP_025818118	DNA topoisomerase I [Vibrio parahaemolyticus].	22.98	544	329	21	7	505	6	504	6e-13	82.4
tr:W6LVX3_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.68	616	336	26	7	568	8	549	6e-13	82.4
rs:WP_039453633	DNA topoisomerase III, partial [Vibrio vulnificus].	26.24	263	176	7	4	260	1	251	6e-13	79.3
rs:WP_042396551	DNA topoisomerase I [Clostridium sp. JCC].	24.24	524	322	19	7	505	6	479	6e-13	82.0
rs:WP_038289162	DNA topoisomerase I [[Clostridium] straminisolvens].	24.42	606	352	22	7	579	6	538	6e-13	82.0
rs:WP_045924935	DNA topoisomerase I [Bifidobacterium asteroides].	22.60	553	332	21	7	505	8	518	6e-13	82.4
rs:WP_026791387	DNA topoisomerase I [Pleomorphomonas oryzae].	24.73	562	303	24	7	510	4	503	6e-13	82.4
rs:WP_025639521	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	6e-13	82.0
rs:WP_036313419	DNA topoisomerase I [Microbacterium oleivorans].	23.02	543	337	20	7	505	8	513	6e-13	82.4
rs:WP_038498484	DNA topoisomerase I [Candidatus Baumannia cicadellinicola].	23.18	535	330	21	7	505	6	495	6e-13	82.4
tr:A0A061JF49_9CHLA	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	26.13	333	194	12	5	322	4	299	6e-13	79.7
rs:WP_001970574	DNA topoisomerase, partial [Helicobacter pylori].	24.87	398	270	16	34	418	30	411	7e-13	81.6
tr:A7NJW2_ROSCS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.94	545	330	16	7	505	6	506	7e-13	82.4
rs:WP_036290936	DNA topoisomerase I [Methylosinus sp. PW1].	23.89	519	303	24	34	505	18	491	7e-13	82.4
rs:WP_003679896	topoisomerase I [Lactobacillus coryniformis].	31.71	205	118	8	5	201	3	193	7e-13	78.2
rs:WP_017832494	DNA topoisomerase I [Kocuria sp. UCD-OTCP].	24.51	567	310	22	7	505	16	532	7e-13	82.4
gp:Z14112_2	DNA topoisomerase I [Bacillus firmus]	29.11	237	146	9	302	527	1	226	7e-13	79.0
tr:U2JGA9_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	29.60	223	140	8	319	531	1	216	7e-13	78.6
rs:WP_032139562	DNA topoisomerase I [Rickettsia tamurae].	24.18	546	324	23	7	510	4	501	7e-13	82.0
rs:WP_026972497	DNA topoisomerase I [Aliagarivorans marinus].	24.25	466	291	18	69	505	75	507	7e-13	82.4
tr:A0A072NRK6_BACAZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.76	424	265	15	112	504	106	506	7e-13	82.0
rs:WP_002230188	DNA topoisomerase I [Neisseria meningitidis].	24.72	534	316	21	7	505	6	488	7e-13	82.0
rs:WP_023660707	DNA topoisomerase I [Pseudomonas taiwanensis].	25.37	477	295	16	97	555	75	508	7e-13	82.0
rs:WP_020762913	DNA topoisomerase I [Leptospira kirschneri].	24.76	529	314	20	1	505	1	469	7e-13	81.6
rs:WP_037287953	DNA topoisomerase I [Rothia dentocariosa].	24.21	603	349	21	7	566	12	549	7e-13	82.4
rs:WP_034165152	DNA topoisomerase I [Edwardsiella tarda].	24.32	440	283	17	88	505	87	498	7e-13	82.4
rs:WP_015787846	DNA topoisomerase I [Saccharomonospora viridis].	23.01	552	337	19	7	505	21	537	7e-13	82.4
tr:G9YWW3_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.70	577	341	23	7	553	2	503	7e-13	82.0
tr:A0A0D6NAU5_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN62760.1};	25.00	552	314	25	7	510	5	504	7e-13	82.4
rs:WP_012902943	DNA topoisomerase I [Rothia mucilaginosa].	23.97	609	343	21	7	566	12	549	7e-13	82.4
rs:WP_040752684	DNA topoisomerase I [Tetrasphaera elongata].	23.51	553	330	19	7	505	12	525	7e-13	82.4
rs:WP_028700188	DNA topoisomerase I [Pseudomonas monteilii].	25.37	477	295	16	97	555	75	508	7e-13	82.0
rs:WP_008765309	MULTISPECIES: DNA topoisomerase I [Bacteroides].	24.81	524	308	19	7	504	6	469	7e-13	82.0
rs:WP_029299451	DNA topoisomerase I [Aeromonas hydrophila].	21.85	540	337	17	7	505	6	501	7e-13	82.0
rs:WP_040085309	DNA topoisomerase III, partial [Escherichia coli].	29.82	228	136	5	338	544	2	226	7e-13	80.9
rs:WP_003775245	DNA topoisomerase I [Neisseria elongata].	24.63	540	309	21	7	505	6	488	7e-13	82.0
rs:WP_018975043	DNA topoisomerase I [Saccharibacillus kuerlensis].	23.00	526	329	18	7	505	6	482	7e-13	82.0
rs:WP_040926792	DNA topoisomerase I [Saccharomonospora marina].	24.29	560	333	21	7	510	1	525	7e-13	82.4
rs:WP_017409144	topoisomerase I [Aeromonas hydrophila].	21.85	540	337	17	7	505	6	501	7e-13	82.0
tr:E2NDW4_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.76	521	314	19	7	505	16	480	7e-13	82.0
rs:WP_022450308	DNA topoisomerase [Roseburia sp. CAG:303].	25.61	285	169	8	307	553	2	281	7e-13	80.1
rs:WP_038911200	DNA topoisomerase I [Dickeya dadantii].	24.72	441	280	16	88	505	90	501	7e-13	82.0
rs:XP_008189109	PREDICTED: DNA topoisomerase 3-alpha-like, partial [Acyrthosiphon pisum].	25.95	420	244	18	115	505	1	382	7e-13	81.3
rs:WP_044050185	DNA topoisomerase I [Planktomarina temperata].	24.81	536	313	25	4	504	1	481	7e-13	82.0
rs:WP_044203945	DNA topoisomerase I [Flammeovirga sp. OC4].	24.52	522	312	20	7	505	6	468	7e-13	82.0
rs:WP_022033928	DNA topoisomerase [Clostridium sp. CAG:710].	24.15	530	312	22	7	506	6	475	7e-13	82.0
rs:WP_016194266	DNA topoisomerase I [Arcticibacter svalbardensis].	25.39	453	262	15	89	504	59	472	7e-13	82.0
rs:WP_025408392	DNA topoisomerase I [Borrelia coriaceae].	23.50	600	349	23	7	561	7	541	7e-13	82.0
rs:WP_008683354	DNA topoisomerase I [Desulfovibrio sp. 3_1_syn3].	26.20	439	279	15	91	505	61	478	7e-13	82.0
rs:WP_022661992	DNA topoisomerase I [Desulfovibrio longus].	25.09	538	318	23	7	510	6	492	7e-13	82.0
rs:WP_022238238	DNA topoisomerase [Clostridium sp. CAG:343].	24.22	611	348	25	7	581	6	537	7e-13	82.0
rs:WP_021023936	topoisomerase I [Salinivibrio costicola].	24.84	459	294	16	69	505	74	503	7e-13	82.0
rs:WP_029584712	DNA topoisomerase I [Bradyrhizobium sp. URHD0069].	23.13	536	334	18	4	505	1	492	7e-13	82.0
rs:WP_039913780	DNA topoisomerase I [Cellvibrio mixtus].	22.10	466	321	14	58	505	68	509	7e-13	82.0
rs:WP_020210395	topoisomerase I [Gilvimarinus chinensis].	22.36	550	330	19	7	505	6	509	7e-13	82.0
rs:WP_022956231	topoisomerase I [Perlucidibaca piscinae].	22.32	542	339	18	7	505	6	508	7e-13	82.0
rs:WP_022611830	DNA topoisomerase [Vibrio nigripulchritudo].	22.26	584	364	20	7	545	3	541	7e-13	82.0
sp:TOP1_LACLA	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.43	527	305	24	7	504	29	496	7e-13	82.0
rs:WP_037235776	DNA topoisomerase I [Rothia dentocariosa].	24.21	603	349	21	7	566	12	549	7e-13	82.0
rs:WP_013317897	topoisomerase I [Dickeya dadantii].	25.11	450	267	18	88	505	89	500	7e-13	82.0
rs:WP_041331875	DNA topoisomerase I, partial [Roseiflexus castenholzii].	22.94	545	330	16	7	505	6	506	7e-13	82.0
rs:WP_023189256	DNA topoisomerase 1 [Lactococcus lactis].	25.43	527	305	24	7	504	29	496	7e-13	82.0
rs:WP_015426411	DNA topoisomerase I [Lactococcus lactis].	25.43	527	305	24	7	504	29	496	7e-13	82.0
rs:WP_021974605	DNA topoisomerase [Firmicutes bacterium CAG:884].	23.22	534	306	19	7	506	6	469	7e-13	82.0
rs:WP_032380053	DNA topoisomerase I [Rhodococcus fascians].	25.34	592	335	24	7	550	19	551	7e-13	82.0
rs:WP_033008161	MULTISPECIES: DNA topoisomerase I [Bacillaceae].	23.47	524	326	16	7	504	6	480	7e-13	82.0
rs:WP_033016014	DNA topoisomerase I [Geobacillus stearothermophilus].	23.47	524	326	16	7	504	6	480	7e-13	82.0
rs:WP_021928053	DNA topoisomerase [Alistipes sp. CAG:831].	25.29	526	301	23	7	504	6	467	7e-13	82.0
rs:WP_040484655	DNA topoisomerase I [Lyngbya aestuarii].	22.22	594	368	16	5	566	3	534	8e-13	82.0
tr:N0E0E4_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.51	553	330	19	7	505	15	528	8e-13	82.0
rs:WP_041321546	DNA topoisomerase I [Rothia dentocariosa].	23.80	605	349	22	7	566	12	549	8e-13	82.0
rs:WP_003146872	DNA topoisomerase I [Gemella haemolysans].	24.42	430	278	15	99	504	70	476	8e-13	82.0
rs:WP_034454831	DNA topoisomerase I [Bartonella henselae].	24.68	547	313	25	4	505	1	493	8e-13	82.0
rs:WP_047112909	DNA topoisomerase I [Brachyspira hyodysenteriae].	23.82	571	339	22	7	553	29	527	8e-13	82.0
tr:A7HLU3_FERNB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.06	564	318	25	7	550	43	527	8e-13	82.0
rs:WP_015856428	DNA topoisomerase I [Bartonella grahamii].	24.64	552	307	27	4	505	1	493	8e-13	82.0
rs:WP_043121319	DNA topoisomerase I [Aeromonas hydrophila].	21.93	538	339	16	7	505	6	501	8e-13	82.0
rs:WP_040493737	DNA topoisomerase I [Ilumatobacter nonamiensis].	24.19	558	317	22	7	510	6	511	8e-13	82.0
rs:WP_020064141	DNA topoisomerase I [Brachyspira hyodysenteriae].	23.82	571	339	22	7	553	29	527	8e-13	82.0
rs:WP_007221678	DNA topoisomerase I [planctomycete KSU-1].	25.05	535	312	22	7	505	9	490	8e-13	82.0
rs:WP_029290883	DNA topoisomerase I [Cellulomonas sp. HZM].	22.94	558	328	19	7	505	6	520	8e-13	82.0
rs:WP_047103157	DNA topoisomerase I [Brachyspira hyodysenteriae].	23.82	571	339	22	7	553	29	527	8e-13	82.0
rs:WP_047101136	DNA topoisomerase I [Brachyspira hyodysenteriae].	23.82	571	339	22	7	553	29	527	8e-13	82.0
tr:W5UTM6_9MOLU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.88	521	326	19	7	504	5	467	8e-13	81.6
rs:WP_014120686	DNA topoisomerase I [Rickettsia japonica].	24.36	546	323	23	7	510	4	501	8e-13	82.0
rs:WP_022195275	DNA topoisomerase [Azospirillum sp. CAG:239].	24.86	531	313	21	7	504	4	481	8e-13	82.0
rs:WP_038276105	DNA topoisomerase I, partial [actinobacterium acAMD-5].	23.99	546	312	22	7	505	12	501	8e-13	82.0
rs:WP_028430727	DNA topoisomerase I [Streptomyces sp. TAA204].	23.83	554	326	21	7	505	15	527	8e-13	82.0
rs:WP_028454731	DNA topoisomerase I [Chitinilyticum litopenaei].	24.86	555	307	22	7	510	6	501	8e-13	82.0
rs:WP_006669315	DNA topoisomerase I [Arthrospira maxima].	22.86	608	347	20	5	566	3	534	8e-13	82.0
rs:WP_022332091	DNA topoisomerase [Alistipes sp. CAG:29].	23.29	541	293	19	7	504	6	467	8e-13	82.0
rs:WP_047110804	DNA topoisomerase I [Brachyspira hyodysenteriae].	23.82	571	339	22	7	553	29	527	8e-13	82.0
rs:WP_040313025	DNA topoisomerase I [Actinomyces coleocanis].	24.06	557	330	16	7	505	6	527	8e-13	82.0
rs:WP_011524140	DNA topoisomerase [Candidatus Koribacter versatilis].	22.57	647	375	27	7	605	6	574	8e-13	82.0
rs:WP_039615782	DNA topoisomerase I [Rhodobacteraceae bacterium PD-2].	24.73	465	280	19	4	449	1	414	8e-13	82.0
rs:WP_009946467	DNA topoisomerase I [Saccharopolyspora erythraea].	24.91	562	325	24	7	510	2	524	8e-13	82.0
rs:WP_035759138	DNA topoisomerase I [Arthrospira platensis].	22.86	608	347	20	5	566	3	534	8e-13	82.0
rs:WP_032404601	DNA topoisomerase I [Rhodococcus fascians].	25.34	592	335	24	7	550	19	551	8e-13	82.0
rs:WP_021092005	DNA topoisomerase I [Campylobacter concisus].	24.86	535	302	23	5	504	4	473	8e-13	81.6
rs:WP_035383427	DNA topoisomerase I, partial [Ferriphaselus sp. R-1].	25.84	538	309	21	7	505	6	492	8e-13	82.0
rs:WP_037975704	DNA topoisomerase I [Synergistes jonesii].	23.83	579	350	18	5	559	84	595	8e-13	82.0
rs:WP_008757996	DNA topoisomerase I [Rhodobacteraceae bacterium KLH11].	26.72	348	191	15	4	335	1	300	8e-13	82.0
rs:WP_026512315	DNA topoisomerase I [Butyrivibrio sp. NC2007].	25.00	444	277	20	93	504	57	476	8e-13	81.6
rs:WP_000520423	topoisomerase I [Vibrio albensis].	24.02	458	299	16	69	505	76	505	8e-13	82.0
rs:WP_045960321	DNA topoisomerase I [Candidatus Liberibacter solanacearum].	25.83	542	312	25	4	505	1	492	8e-13	82.0
rs:WP_018226836	DNA topoisomerase I [actinobacterium SCGC AAA023-D18].	23.82	550	324	21	7	505	6	511	8e-13	82.0
tr:A4AKC9_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.96	577	334	24	7	540	8	528	8e-13	82.0
rs:WP_007944143	topoisomerase I [Pseudomonas sp. GM21].	22.45	530	350	17	7	505	6	505	8e-13	82.0
rs:WP_015925504	DNA topoisomerase I [[Clostridium] cellulolyticum].	23.75	539	314	22	7	504	6	488	8e-13	81.6
rs:WP_005588136	DNA topoisomerase I [Clostridium ultunense].	24.01	529	319	19	7	505	6	481	8e-13	81.6
rs:WP_022164626	DNA topoisomerase [Eubacterium sp. CAG:192].	25.06	439	272	18	97	504	67	479	8e-13	81.6
rs:WP_002221835	DNA topoisomerase I [Neisseria meningitidis].	24.62	532	319	19	7	505	6	488	8e-13	82.0
rs:WP_005878152	DNA topoisomerase I [Enterococcus durans].	23.95	526	321	18	7	504	7	481	8e-13	81.6
rs:WP_010483129	topoisomerase I [Pseudomonas sp. S9].	23.03	534	341	17	7	505	6	504	8e-13	82.0
rs:NP_224964	DNA topoisomerase I [Chlamydophila pneumoniae CWL029].	24.71	599	339	23	7	563	6	534	8e-13	82.0
tr:A0A096BQP1_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGF44992.1}; Flags: Fragment;	25.41	244	157	7	321	552	5	235	8e-13	80.5
rs:WP_028025214	DNA topoisomerase I [Enterovibrio calviensis].	23.52	455	305	15	69	505	74	503	8e-13	82.0
rs:WP_019496473	hypothetical protein [Calothrix sp. PCC 7103].	25.73	482	294	17	105	561	82	524	8e-13	81.6
rs:WP_036141355	DNA topoisomerase I [Lysinibacillus sp. BF-4].	26.11	429	252	16	112	504	82	481	8e-13	81.6
rs:WP_044126648	DNA topoisomerase I [Vibrio cholerae].	22.47	543	334	18	7	505	6	505	8e-13	82.0
rs:WP_005508282	DNA topoisomerase I [Rothia mucilaginosa].	23.97	609	343	21	7	566	12	549	8e-13	82.0
rs:WP_038661211	DNA topoisomerase I [Pseudomonas stutzeri].	21.97	537	341	18	7	505	6	502	8e-13	82.0
rs:WP_037149138	DNA topoisomerase I [Rhodococcus fascians].	25.34	592	335	24	7	550	19	551	8e-13	82.0
rs:WP_006201781	DNA topoisomerase I [Mesorhizobium amorphae].	24.63	540	321	22	4	505	1	492	8e-13	82.0
rs:WP_024493786	DNA topoisomerase I [Streptomyces sp. AW19M42].	23.61	559	321	22	7	505	15	527	8e-13	82.0
rs:WP_033928613	DNA topoisomerase I [Vibrio cholerae].	22.47	543	334	18	7	505	6	505	8e-13	82.0
tr:C0W269_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.06	557	330	16	7	505	12	533	9e-13	82.0
rs:WP_002032552	DNA topoisomerase I [Vibrio cholerae].	22.47	543	334	18	7	505	6	505	9e-13	82.0
rs:WP_025503111	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	9e-13	82.0
rs:WP_024512407	DNA topoisomerase I [Bradyrhizobium sp. ARR65].	23.09	537	333	20	4	505	1	492	9e-13	82.0
rs:WP_015044145	MULTISPECIES: DNA topoisomerase I [Dehalobacter].	24.07	536	321	21	3	505	2	484	9e-13	81.6
rs:WP_030446875	DNA topoisomerase I [Actinocatenispora sera].	23.76	564	327	20	2	505	6	526	9e-13	82.0
rs:WP_036816340	DNA topoisomerase I [Pontibacillus yanchengensis].	25.24	420	269	13	112	505	82	482	9e-13	81.6
rs:WP_026662512	DNA topoisomerase I [Butyrivibrio proteoclasticus].	25.34	442	278	18	93	504	57	476	9e-13	81.6
tr:X0ZSC2_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_C01715 {ECO:0000313|EMBL:GAG72680.1}; Flags: Fragment;	22.62	420	285	12	7	414	4	395	9e-13	80.9
rs:WP_017246024	topoisomerase I [Pseudomonas stutzeri].	22.22	540	336	18	7	505	6	502	9e-13	82.0
rs:WP_015122729	DNA topoisomerase I [Rivularia sp. PCC 7116].	24.91	582	330	21	46	579	29	551	9e-13	82.0
tr:A0A088TKF3_9MOLU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.75	431	275	15	93	504	65	469	9e-13	81.6
rs:WP_046830945	DNA topoisomerase I [Xanthomonas axonopodis].	26.12	356	226	12	107	452	75	403	9e-13	81.6
rs:WP_045805442	DNA topoisomerase I [Rickettsia argasii].	25.27	455	283	18	96	510	64	501	9e-13	81.6
rs:WP_003368297	DNA topoisomerase I [Clostridium botulinum].	23.62	542	333	20	7	517	6	497	9e-13	81.6
tr:K1W611_ARTPT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.86	608	347	20	5	566	11	542	9e-13	82.0
rs:WP_011180711	DNA topoisomerase I [Bartonella henselae].	24.73	546	312	25	4	504	1	492	9e-13	82.0
rs:WP_003332525	DNA topoisomerase I [Bacillus azotoformans].	25.35	426	260	17	112	504	82	482	9e-13	81.6
tr:K2CJS5_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	28.74	348	187	16	7	336	5	309	9e-13	80.5
rs:WP_033106624	DNA topoisomerase I [Microbacterium profundi].	23.35	544	333	20	7	505	8	512	9e-13	82.0
rs:WP_005466649	DNA topoisomerase I [Saccharomonospora glauca].	23.09	550	339	18	7	505	21	537	9e-13	82.0
rs:WP_011534822	topoisomerase I [Pseudomonas entomophila].	22.83	530	347	17	7	505	6	504	9e-13	82.0
rs:WP_040181922	DNA topoisomerase I [Phaeobacter sp. S60].	24.87	571	307	26	4	510	1	513	9e-13	82.0
rs:WP_040800812	DNA topoisomerase I [marine actinobacterium PHSC20C1].	24.96	577	334	24	7	540	16	536	9e-13	82.0
rs:WP_041436909	DNA topoisomerase I [Thermomicrobium roseum].	24.45	544	312	22	7	504	2	492	9e-13	81.6
tr:A0A094PGW1_9ACTN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	546	312	22	7	505	12	501	9e-13	82.0
rs:WP_036881443	DNA topoisomerase I [Porphyromonas sp. COT-239 OH1446].	23.33	450	291	16	80	505	52	471	9e-13	81.6
rs:WP_039252884	DNA topoisomerase I [Clostridium novyi].	23.80	542	332	20	7	517	6	497	9e-13	81.6
rs:WP_011912884	topoisomerase I [Pseudomonas stutzeri].	22.22	540	336	18	7	505	6	502	9e-13	82.0
rs:WP_011316928	DNA topoisomerase I [Anabaena variabilis].	24.06	507	300	14	95	566	78	534	9e-13	82.0
rs:WP_041257161	DNA topoisomerase I, partial [Fervidobacterium nodosum].	26.06	564	318	25	7	550	10	494	9e-13	81.6
rs:WP_000520432	topoisomerase I [Vibrio cholerae].	24.02	458	299	16	69	505	76	505	9e-13	82.0
rs:WP_002239431	DNA topoisomerase I [Neisseria meningitidis].	24.72	534	316	21	7	505	6	488	9e-13	81.6
rs:WP_023614906	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.43	524	321	18	7	504	6	480	9e-13	81.6
rs:WP_022325316	DNA topoisomerase [Clostridium sp. CAG:798].	23.87	641	364	26	7	606	6	563	9e-13	81.6
rs:WP_038467628	DNA topoisomerase I [Mollicutes bacterium HR1].	25.75	431	275	15	93	504	66	470	9e-13	81.6
rs:WP_000520435	topoisomerase I [Vibrio cholerae].	22.47	543	334	18	7	505	6	505	9e-13	81.6
rs:WP_033572549	DNA topoisomerase I [Bacteroides sp. UW].	21.79	569	373	22	4	550	1	519	9e-13	81.3
rs:WP_022435372	DNA topoisomerase [Firmicutes bacterium CAG:321].	24.07	536	305	22	7	506	6	475	9e-13	81.6
rs:WP_028946757	DNA topoisomerase I [Synechocystis sp. PCC 6714].	23.85	545	325	19	91	603	74	560	9e-13	82.0
rs:WP_027906307	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	22.37	532	346	17	7	505	6	503	9e-13	81.6
rs:WP_015050175	DNA topoisomerase I [Thermacetogenium phaeum].	25.17	572	326	23	7	553	6	500	9e-13	81.6
rs:WP_014014146	DNA topoisomerase I [Rickettsia heilongjiangensis].	24.18	546	324	23	7	510	4	501	9e-13	81.6
tr:E3H0I0_ROTDC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.80	605	349	22	7	566	16	553	9e-13	82.0
rs:WP_018362460	DNA topoisomerase I [Prevotella nanceiensis].	24.67	527	306	19	7	504	6	470	9e-13	81.6
rs:WP_012719587	DNA topoisomerase I [Rickettsia africae].	24.36	546	323	23	7	510	4	501	9e-13	81.6
rs:WP_046874733	DNA topoisomerase I [Vibrio alginolyticus].	22.74	541	334	20	7	505	6	504	9e-13	81.6
rs:WP_024267208	DNA topoisomerase I [Salinispira pacifica].	23.51	587	339	25	7	544	8	533	9e-13	81.6
rs:WP_040760362	DNA topoisomerase I [Weissella paramesenteroides].	23.87	532	314	19	7	505	23	496	9e-13	81.6
rs:WP_019476900	DNA topoisomerase I [Prochlorococcus sp. W7].	24.81	516	297	20	101	579	85	546	9e-13	81.6
rs:WP_020260876	hypothetical protein [Candidatus Aminicenans sakinawicola].	22.90	524	327	20	7	505	6	477	9e-13	81.6
rs:WP_022025442	DNA topoisomerase [Clostridium sp. CAG:75].	23.81	441	278	15	97	505	67	481	1e-12	81.6
rs:WP_006886374	DNA topoisomerase I [Mycoplasma anatis].	22.69	542	320	21	5	510	3	481	1e-12	81.3
rs:WP_015904582	DNA topoisomerase I [Desulfobacterium autotrophicum].	24.76	513	312	21	38	514	22	496	1e-12	81.6
rs:WP_022760179	MULTISPECIES: DNA topoisomerase I [Butyrivibrio].	24.60	443	282	19	93	505	66	486	1e-12	81.6
rs:WP_029006159	DNA topoisomerase I [Azorhizobium doebereinerae].	24.73	554	319	23	4	510	1	503	1e-12	81.6
rs:WP_012897826	DNA topoisomerase I [Lactococcus lactis].	25.43	527	305	24	7	504	29	496	1e-12	81.6
tr:D4L803_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.19	520	306	22	7	498	5	469	1e-12	81.6
rs:WP_046431670	DNA topoisomerase I [Ruminococcus sp. A254.MGS-108].	25.19	520	306	22	7	498	5	469	1e-12	81.6
tr:W7AT25_PLAVN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EUD71779.1};	24.62	528	277	24	83	531	89	574	1e-12	81.6
rs:WP_039358543	DNA topoisomerase I [Pectobacterium carotovorum].	25.28	443	275	18	88	505	88	499	1e-12	81.6
rs:WP_002712162	DNA topoisomerase I [Afipia clevelandensis].	24.54	538	318	23	7	505	4	492	1e-12	81.6
rs:WP_014262163	DNA topoisomerase I [Filifactor alocis].	25.48	522	315	22	7	504	6	477	1e-12	81.6
rs:WP_047104919	DNA topoisomerase I [Brachyspira hyodysenteriae].	23.82	571	339	22	7	553	29	527	1e-12	81.6
tr:T0ZRV5_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD47393.1}; Flags: Fragment;	30.56	180	101	7	200	368	1	167	1e-12	77.4
rs:WP_009021608	topoisomerase I [Luminiphilus syltensis].	23.62	542	333	20	7	505	6	509	1e-12	81.6
tr:C5RBD7_WEIPA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.87	532	314	19	7	505	37	510	1e-12	81.6
rs:WP_012672070	DNA topoisomerase I [Brachyspira hyodysenteriae].	23.82	571	339	22	7	553	29	527	1e-12	81.6
rs:WP_042987746	DNA topoisomerase I [Vibrio cholerae].	24.02	458	299	16	69	505	76	505	1e-12	81.6
rs:WP_039562051	DNA topoisomerase I [Serpens flexibilis].	22.47	534	342	17	7	505	6	502	1e-12	81.6
rs:WP_036621536	DNA topoisomerase I [Paenibacillus alvei].	24.77	440	284	15	92	504	62	481	1e-12	81.6
rs:WP_021700517	DNA topoisomerase I [Pseudomonas alcaligenes].	24.19	430	275	15	99	505	103	504	1e-12	81.6
rs:WP_010249084	DNA topoisomerase I [Acetivibrio cellulolyticus].	25.04	575	330	22	7	553	6	507	1e-12	81.6
rs:WP_000520433	topoisomerase I [Vibrio cholerae].	22.47	543	334	18	7	505	6	505	1e-12	81.6
rs:WP_033604912	MULTISPECIES: DNA topoisomerase, partial [Enterococcus].	27.60	221	150	6	332	544	1	219	1e-12	79.3
tr:E6PFJ4_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CBH75230.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBH75230.1};	26.98	441	273	16	93	504	63	483	1e-12	81.6
rs:WP_026520741	DNA topoisomerase I [Butyrivibrio sp. VCB2001].	25.00	444	277	20	93	504	57	476	1e-12	81.3
rs:WP_030122938	DNA topoisomerase I [[Kitasatospora] papulosa].	23.26	559	323	22	7	505	13	525	1e-12	81.6
rs:WP_031090918	DNA topoisomerase I [Streptomyces sp. NRRL S-15].	22.72	559	326	21	7	505	13	525	1e-12	81.6
rs:WP_006378971	Topoisomerase IA [Streptomyces turgidiscabies].	23.94	447	278	21	1	425	1	407	1e-12	81.6
rs:WP_039489912	MULTISPECIES: DNA topoisomerase I [Pseudoalteromonas].	23.06	438	291	13	88	505	96	507	1e-12	81.6
tr:A0A096CLF8_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGF46149.1}; Flags: Fragment;	25.11	223	144	6	321	531	5	216	1e-12	80.1
rs:WP_025643987	MULTISPECIES: DNA topoisomerase I [Psychrobacter].	23.82	445	287	14	88	505	140	559	1e-12	81.6
rs:WP_008826392	DNA topoisomerase I [Haloplasma contractile].	24.67	523	320	20	7	504	6	479	1e-12	81.6
rs:WP_043842115	DNA topoisomerase I [Roseivivax atlanticus].	24.95	493	290	19	4	469	1	440	1e-12	81.6
rs:WP_033379005	MULTISPECIES: DNA topoisomerase I, partial [Mycoplasma].	21.88	521	326	19	7	504	5	467	1e-12	81.3
tr:B9L0B0_THERP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.45	544	312	22	7	504	38	528	1e-12	81.6
rs:WP_031534466	DNA topoisomerase I [Bacillus sp. MB2021].	25.36	422	263	16	112	504	82	480	1e-12	81.3
rs:WP_029837348	DNA topoisomerase I [Vibrio parahaemolyticus].	22.69	542	333	20	7	505	6	504	1e-12	81.6
rs:WP_041104791	DNA topoisomerase I [Pseudomonas stutzeri].	22.73	528	346	16	7	505	6	500	1e-12	81.6
rs:WP_041483233	hypothetical protein, partial [Thioalkalimicrobium aerophilum].	24.24	524	322	22	8	515	5	469	1e-12	80.9
rs:WP_040527233	DNA topoisomerase I [Gordonia paraffinivorans].	23.27	550	334	19	7	505	18	530	1e-12	81.6
rs:WP_035801076	DNA topoisomerase I [Butyrivibrio sp. FCS014].	24.83	447	274	19	93	504	59	478	1e-12	81.3
rs:WP_000520429	topoisomerase I [Vibrio cholerae].	24.02	458	299	16	69	505	76	505	1e-12	81.6
tr:A0A0D6MI16_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN52913.1};	24.91	550	315	26	7	510	14	511	1e-12	81.6
rs:WP_036887905	DNA topoisomerase I, partial [Prevotella maculosa].	26.27	236	151	6	5	232	3	223	1e-12	78.6
rs:WP_002237530	DNA topoisomerase I [Neisseria meningitidis].	24.72	534	316	21	7	505	6	488	1e-12	81.6
rs:WP_040172041	DNA topoisomerase I [Phaeobacter sp. S26].	24.87	571	307	26	4	510	1	513	1e-12	81.6
rs:WP_038151022	DNA topoisomerase I [Vibrio furnissii].	22.61	544	332	18	7	505	6	505	1e-12	81.6
rs:WP_006888270	DNA topoisomerase I [Rothia aeria].	23.97	605	348	22	7	566	12	549	1e-12	81.6
rs:WP_046514712	DNA topoisomerase I [Bacillus sp. SA1-12].	25.65	421	263	13	112	504	82	480	1e-12	81.3
tr:J9Z7K0_LEPFM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.07	482	291	20	80	512	18	473	1e-12	81.6
rs:WP_002238601	DNA topoisomerase I [Neisseria meningitidis].	24.62	532	319	19	7	505	6	488	1e-12	81.6
rs:WP_023379575	DNA topoisomerase I subunit omega [Pseudomonas sp. VLB120].	22.72	537	339	19	7	505	6	504	1e-12	81.6
rs:WP_027155146	DNA topoisomerase I [Mesorhizobium sp. WSM2561].	24.82	544	315	22	4	505	1	492	1e-12	81.6
rs:WP_031813486	DNA topoisomerase I [Vibrio parahaemolyticus].	22.69	542	333	20	7	505	6	504	1e-12	81.6
rs:WP_036881465	DNA topoisomerase I, partial [Prevotella nigrescens].	28.64	213	129	6	331	531	1	202	1e-12	80.1
rs:WP_002959733	topoisomerase I [Pseudoalteromonas haloplanktis].	23.06	438	291	13	88	505	96	507	1e-12	81.6
sp:TOP1_VIBCH	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.02	458	299	16	69	505	76	505	1e-12	81.6
rs:WP_021414805	DNA topoisomerase I [Peptoclostridium difficile].	26.23	530	307	25	5	504	4	479	1e-12	81.3
rs:WP_012170389	DNA topoisomerase I [Azorhizobium caulinodans].	25.44	562	305	27	4	510	1	503	1e-12	81.6
rs:WP_037039426	DNA topoisomerase I [Pseudomonas sp. BAY1663].	22.30	538	337	19	7	505	6	501	1e-12	81.6
rs:WP_023048968	topoisomerase I [Pseudomonas putida].	23.21	530	345	17	7	505	6	504	1e-12	81.6
rs:WP_046121520	DNA topoisomerase I [Vibrio cholerae].	24.02	458	299	16	69	505	76	505	1e-12	81.6
rs:WP_033929724	DNA topoisomerase I [Vibrio cholerae].	24.02	458	299	16	69	505	76	505	1e-12	81.6
rs:WP_027589307	DNA topoisomerase I [Pseudomonas sp. RL].	22.47	534	342	17	7	505	6	502	1e-12	81.6
rs:WP_014155474	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.26	559	323	22	7	505	13	525	1e-12	81.6
rs:WP_000520430	topoisomerase I [Vibrio cholerae].	24.02	458	299	16	69	505	76	505	1e-12	81.6
rs:WP_001897682	topoisomerase I [Vibrio cholerae].	24.02	458	299	16	69	505	76	505	1e-12	81.6
rs:WP_005845602	DNA topoisomerase I [Prevotella dentalis].	24.65	568	331	22	7	543	6	507	1e-12	81.3
rs:WP_025566026	DNA topoisomerase I [Psychromonas sp. SP041].	25.36	418	268	15	107	505	114	506	1e-12	81.6
rs:WP_042481986	DNA topoisomerase I [Vibrio diazotrophicus].	23.74	455	304	14	69	505	77	506	1e-12	81.6
rs:WP_001886798	topoisomerase I [Vibrio cholerae].	24.02	458	299	16	69	505	76	505	1e-12	81.6
tr:J7T930_CLOSG	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.50	549	316	24	7	517	10	503	1e-12	81.3
rs:WP_015508496	hypothetical protein [Rickettsia prowazekii].	24.89	458	281	17	96	510	64	501	1e-12	81.3
rs:WP_031571001	DNA topoisomerase I [Rheinheimera texasensis].	24.25	536	323	22	7	505	6	495	1e-12	81.6
rs:WP_002232259	DNA topoisomerase I [Neisseria meningitidis].	24.72	534	316	21	7	505	6	488	1e-12	81.3
rs:WP_005709862	topoisomerase I [Haemophilus paraphrohaemolyticus].	24.89	442	281	17	86	505	92	504	1e-12	81.6
rs:WP_011163504	DNA topoisomerase I [Bdellovibrio bacteriovorus].	23.04	625	391	19	3	590	10	581	1e-12	81.6
rs:WP_018265474	DNA topoisomerase I [Methylosinus sp. LW4].	23.89	519	303	24	34	505	18	491	1e-12	81.6
rs:WP_015929895	DNA topoisomerase I [Methylobacterium nodulans].	23.73	552	326	24	4	510	1	502	1e-12	81.6
rs:WP_011014686	topoisomerase I [Corynebacterium glutamicum].	24.26	441	273	17	7	424	5	407	1e-12	81.3
rs:WP_045428428	DNA topoisomerase I [Pseudomonas sp. MT-1].	22.35	537	339	18	7	505	6	502	1e-12	81.6
rs:WP_015955427	DNA topoisomerase I [Cyanothece sp. PCC 7424].	24.57	460	275	16	91	505	74	506	1e-12	81.6
rs:WP_013805099	DNA topoisomerase I [Amycolicicoccus subflavus].	24.27	548	331	21	7	505	25	537	1e-12	81.6
rs:WP_002256289	DNA topoisomerase I [Neisseria meningitidis].	24.62	532	319	19	7	505	6	488	1e-12	81.3
tr:A0A090S0S8_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL20084.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL20084.1};	28.78	205	129	6	8	206	6	199	1e-12	78.2
rs:WP_025242302	DNA topoisomerase I [Pseudomonas stutzeri].	23.57	437	290	13	88	505	91	502	1e-12	81.6
tr:L8JM96_9BACT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ELR68512.1};	29.86	221	124	7	317	517	1	210	1e-12	77.8
rs:WP_019152081	DNA topoisomerase I [Alistipes senegalensis].	23.76	526	309	20	7	504	6	467	1e-12	81.3
rs:WP_022273096	DNA topoisomerase [Clostridium sp. CAG:58].	23.93	443	286	17	93	505	63	484	1e-12	81.3
rs:WP_026882308	DNA topoisomerase I [Clostridium akagii].	25.28	534	304	25	7	504	6	480	1e-12	81.3
tr:A0A0A0WVM8_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.50	240	162	5	309	539	3	239	1e-12	80.9
rs:WP_044315429	DNA topoisomerase III, partial [Pseudomonas stutzeri].	31.41	156	95	2	403	548	2	155	1e-12	78.2
rs:WP_027074603	DNA topoisomerase I [Mannheimia granulomatis].	24.06	453	287	17	79	505	83	504	1e-12	81.3
rs:WP_043904103	DNA topoisomerase I [Geobacillus stearothermophilus].	24.76	525	310	20	112	598	82	559	1e-12	81.3
tr:S6F3I0_LACLL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.37	421	263	18	107	504	50	446	1e-12	81.3
rs:WP_007237854	DNA topoisomerase I [Gordonia otitidis].	23.09	550	339	18	7	505	19	535	1e-12	81.6
rs:WP_029018600	DNA topoisomerase I [actinobacterium SCGC AAA028-I14].	23.99	567	325	24	4	510	9	529	1e-12	81.6
rs:WP_025400131	DNA topoisomerase I [Borrelia hermsii].	23.54	599	350	24	7	561	7	541	1e-12	81.3
rs:WP_039655615	DNA topoisomerase I [Clostridium tyrobutyricum].	23.92	531	315	22	7	504	6	480	1e-12	81.3
rs:WP_034841315	DNA topoisomerase I [Endozoicomonas numazuensis].	22.77	470	302	19	57	505	81	510	1e-12	81.3
rs:WP_019340657	topoisomerase I [Pseudomonas stutzeri].	22.35	537	339	18	7	505	6	502	1e-12	81.3
rs:WP_034716810	DNA topoisomerase I [Bacteroides eggerthii].	24.76	521	312	18	7	504	6	469	1e-12	81.3
rs:WP_011077240	DNA topoisomerase I [Mycoplasma penetrans].	23.19	565	352	17	7	543	5	515	1e-12	81.3
tr:Q1QKM0_NITHX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.42	538	333	20	2	505	24	516	1e-12	81.3
rs:WP_029212697	DNA topoisomerase I [Arsenicicoccus bolidensis].	23.16	544	340	18	7	505	10	520	1e-12	81.3
rs:WP_036747808	DNA topoisomerase I [Peptococcaceae bacterium SCADC1_2_3].	24.15	530	324	21	5	505	4	484	1e-12	81.3
rs:WP_032566601	DNA topoisomerase I, partial [Bacteroides fragilis].	28.51	249	154	8	4	242	1	235	1e-12	78.2
rs:WP_010535667	MULTISPECIES: DNA topoisomerase I [Bacteroides].	24.14	526	309	18	7	504	6	469	1e-12	81.3
rs:WP_035619653	DNA topoisomerase I [Lachnoanaerobaculum sp. ICM7].	25.97	439	271	16	97	504	67	482	1e-12	81.3
rs:WP_004319202	DNA topoisomerase I [Campylobacter rectus].	24.53	424	274	15	107	505	72	474	1e-12	80.9
rs:WP_002240198	DNA topoisomerase I [Neisseria meningitidis].	24.44	532	320	19	7	505	6	488	1e-12	81.3
rs:WP_008580070	MULTISPECIES: DNA topoisomerase I [Rickettsia].	24.18	546	324	22	7	510	4	501	1e-12	81.3
rs:WP_019722027	DNA topoisomerase I [Bacillus coagulans].	26.13	421	261	15	112	504	82	480	1e-12	81.3
rs:WP_025569872	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	1e-12	81.3
rs:WP_022608758	DNA topoisomerase I [Rubidibacter lacunae].	25.71	455	272	16	93	505	76	506	1e-12	81.3
rs:WP_028986563	DNA topoisomerase I [Thermicanus aegyptius].	23.82	529	320	19	7	505	6	481	1e-12	81.3
rs:WP_038487602	DNA topoisomerase I [Bartonella henselae].	24.50	547	314	25	4	505	1	493	1e-12	81.3
rs:WP_011722224	MULTISPECIES: DNA topoisomerase I [Clostridium].	23.25	542	335	20	7	517	6	497	1e-12	81.3
rs:WP_016485640	topoisomerase I [Pseudomonas putida].	23.21	530	345	17	7	505	6	504	1e-12	81.3
rs:WP_010649333	DNA topoisomerase I [Oceanobacillus massiliensis].	23.06	529	325	17	7	505	6	482	1e-12	81.3
rs:WP_020442068	DNA topoisomerase I subunit omega [Corynebacterium terpenotabidum].	25.00	488	284	18	86	510	78	546	1e-12	81.3
rs:WP_035379360	DNA topoisomerase I [Acetobacter tropicalis].	23.69	553	320	24	7	510	5	504	1e-12	81.3
rs:WP_010761353	DNA topoisomerase 1 [Enterococcus haemoperoxidus].	24.14	526	320	18	7	504	7	481	1e-12	81.3
rs:WP_036882351	hypothetical protein, partial [Prevotella nigrescens].	27.16	232	144	7	331	550	1	219	1e-12	79.7
rs:WP_046412494	DNA topoisomerase I [Bacteroides sp. N54.MGS-20].	24.19	554	311	21	7	523	6	487	1e-12	81.3
rs:WP_044147101	DNA topoisomerase, partial [Enterococcus faecium].	38.46	130	68	5	5	129	4	126	1e-12	76.6
rs:WP_028595587	DNA topoisomerase I [Paenibacillus assamensis].	26.23	427	264	16	107	504	77	481	1e-12	81.3
rs:WP_024880185	DNA topoisomerase I [Methylosinus sp. LW3].	23.59	513	312	22	34	505	18	491	1e-12	81.3
rs:WP_018346637	topoisomerase I [Gallibacterium anatis].	23.81	441	284	16	88	505	93	504	1e-12	81.3
rs:WP_021991100	DNA topoisomerase [Prevotella sp. CAG:1092].	23.21	560	345	20	7	541	16	515	1e-12	81.3
rs:WP_013502024	DNA topoisomerase I [Rhodopseudomonas palustris].	25.37	540	311	22	7	505	4	492	1e-12	81.3
rs:WP_017201450	DNA topoisomerase I [Microbacterium barkeri].	22.44	557	328	19	7	505	8	518	1e-12	81.3
rs:WP_014518289	DNA topoisomerase I [Chlamydia pneumoniae].	24.71	599	339	23	7	563	6	534	1e-12	81.3
rs:WP_029141585	DNA topoisomerase I [Bacillus coagulans].	26.13	421	261	15	112	504	82	480	1e-12	80.9
rs:WP_006797683	DNA topoisomerase I [Dysgonomonas gadei].	25.19	540	326	19	7	523	6	490	1e-12	81.3
tr:A0A077LXP7_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.86	523	314	22	46	510	33	534	1e-12	81.3
rs:WP_011762147	DNA topoisomerase [Pyrobaculum islandicum].	22.14	569	362	19	7	548	4	518	1e-12	80.9
rs:WP_034449286	DNA topoisomerase I [Bartonella quintana].	24.55	550	308	28	4	504	1	492	1e-12	81.3
tr:C9X1P3_NEIM8	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.72	534	316	21	7	505	6	488	1e-12	81.3
rs:WP_002225938	DNA topoisomerase I [Neisseria meningitidis].	24.53	534	317	21	7	505	6	488	1e-12	81.3
rs:WP_014820598	topoisomerase I [Pseudomonas stutzeri].	22.16	537	340	19	7	505	6	502	1e-12	81.3
rs:WP_020857205	DNA topoisomerase I [SAR86 cluster bacterium SAR86A].	23.65	554	335	19	3	512	2	511	1e-12	81.3
rs:WP_000520424	topoisomerase I [Vibrio cholerae].	24.02	458	299	16	69	505	76	505	1e-12	81.3
rs:WP_041177573	DNA topoisomerase I, partial [Brachyspira intermedia].	23.64	571	340	22	7	553	16	514	1e-12	80.9
rs:WP_042385490	MULTISPECIES: DNA topoisomerase I [Clostridium].	25.50	549	316	24	7	517	6	499	1e-12	80.9
rs:WP_010579950	DNA topoisomerase I [Lactobacillus vini].	23.95	522	322	20	7	504	22	492	1e-12	80.9
sp:TOP1_RICCN	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.18	546	324	23	7	510	4	501	1e-12	81.3
tr:S9SHB1_PAEAL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.77	440	284	15	92	504	74	493	1e-12	80.9
rs:WP_009776219	DNA topoisomerase I [Janibacter sp. HTCC2649].	23.08	546	337	20	7	505	11	520	1e-12	81.3
rs:WP_037148031	topoisomerase I [Rhodococcus fascians].	23.35	484	300	19	7	459	6	449	1e-12	81.3
rs:WP_034233047	DNA topoisomerase I [Arcanobacterium sp. S3PF19].	24.86	547	328	17	7	505	5	516	1e-12	81.3
tr:E6N9Z0_9ARCH	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:BAJ49146.1}; EC=5.99.1.2 {ECO:0000313|EMBL:BAJ49146.1};	23.55	535	330	18	7	527	17	486	1e-12	80.9
tr:E5X107_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.76	521	312	18	7	504	16	479	1e-12	81.3
rs:WP_024599386	DNA topoisomerase I [Pseudoalteromonas haloplanktis].	22.25	454	313	13	69	505	77	507	1e-12	81.3
rs:WP_010001831	DNA topoisomerase I [Leuconostoc lactis].	23.53	527	319	22	7	504	34	505	1e-12	80.9
tr:K1SBE4_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC44731.1}; Flags: Fragment;	28.09	235	147	7	6	232	3	223	1e-12	77.8
tr:E6QI81_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CBI06946.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI06946.1};	24.72	530	301	21	46	510	4	500	1e-12	81.3
rs:WP_005051207	DNA topoisomerase I [Microbacterium laevaniformans].	22.73	550	330	18	7	505	13	518	1e-12	81.3
tr:J5H751_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.97	439	271	16	97	504	62	477	1e-12	80.9
rs:WP_010981052	DNA topoisomerase I [Neisseria meningitidis].	24.62	532	319	19	7	505	6	488	1e-12	81.3
rs:WP_027915088	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	22.87	529	348	17	7	505	6	504	1e-12	81.3
rs:WP_035290647	DNA topoisomerase I [Clostridium sp. KNHs214].	22.96	540	339	19	7	517	6	497	1e-12	80.9
tr:K2EC32_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.79	601	361	24	7	580	4	534	1e-12	80.9
rs:WP_027952528	DNA topoisomerase I [Hallella seregens].	24.65	568	331	22	7	543	6	507	1e-12	81.3
gpu:LN847056_15	DNA topoisomerase 1 [Chlamydia pneumoniae]	24.71	599	339	23	7	563	6	534	1e-12	81.3
tr:E6QED7_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:CBI05563.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI05563.1};	23.64	385	240	12	156	505	8	373	1e-12	80.9
rs:WP_027697125	DNA topoisomerase I [Vibrio litoralis].	22.81	548	324	21	7	505	6	503	1e-12	81.3
rs:WP_021863724	DNA topoisomerase [Clostridium sp. CAG:715].	23.55	535	336	20	107	607	89	584	1e-12	80.9
rs:WP_030588325	DNA topoisomerase I [Streptomyces anulatus].	23.08	559	324	21	7	505	15	527	1e-12	81.3
rs:WP_009849879	DNA topoisomerase I [Mariprofundus ferrooxydans].	24.56	562	323	23	1	515	1	508	1e-12	80.9
rs:WP_015229361	DNA topoisomerase I [Dactylococcopsis salina].	23.95	526	309	18	91	579	74	545	1e-12	81.3
rs:WP_005459856	DNA topoisomerase I [Saccharomonospora cyanea].	22.82	561	343	18	7	510	21	548	1e-12	81.3
rs:WP_014273369	DNA topoisomerase I [Rickettsia slovaca].	24.18	546	324	22	7	510	4	501	2e-12	80.9
rs:WP_018623230	DNA topoisomerase I [Spirosoma luteum].	24.72	445	266	15	7	442	6	390	2e-12	81.3
rs:WP_039249168	DNA topoisomerase I [Clostridium novyi].	23.25	542	335	20	7	517	6	497	2e-12	80.9
tr:T0XX17_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	25.11	462	276	21	91	505	7	445	2e-12	80.1
rs:WP_030635107	DNA topoisomerase I [Streptomyces rimosus].	25.22	460	270	19	97	505	91	527	2e-12	81.3
rs:WP_018038760	DNA topoisomerase I [alpha proteobacterium SCGC AB-629-G21].	24.84	612	351	28	7	581	4	543	2e-12	81.3
rs:WP_042729272	DNA topoisomerase I [Pseudomonas fluorescens].	21.93	456	312	13	69	505	75	505	2e-12	81.3
rs:WP_039409382	DNA topoisomerase I [Morococcus cerebrosus].	24.35	538	313	19	7	505	6	488	2e-12	80.9
rs:WP_016646347	hypothetical protein [Campylobacter ureolyticus].	25.09	530	309	23	5	505	4	474	2e-12	80.9
rs:WP_008751513	DNA topoisomerase I [Lachnoanaerobaculum saburreum].	24.43	438	278	16	97	504	67	481	2e-12	80.9
rs:WP_020980388	DNA topoisomerase I [Leptospira noguchii].	24.95	525	310	20	5	504	3	468	2e-12	80.9
tr:D4KE79_9FIRM	SubName: Full=Draft genome {ECO:0000313|EMBL:CBL06676.1};	32.24	152	85	2	398	531	3	154	2e-12	78.2
rs:WP_015296478	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	81.3
rs:WP_003144692	DNA topoisomerase I [Gemella haemolysans].	24.42	430	278	15	99	504	70	476	2e-12	80.9
rs:WP_013836048	DNA topoisomerase I [Thioalkalimicrobium cyclicum].	23.35	514	325	15	7	504	5	465	2e-12	80.9
rs:WP_015845040	DNA topoisomerase I [Paenibacillus sp. JDR-2].	23.21	530	323	19	7	505	6	482	2e-12	80.9
rs:WP_029823273	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	81.3
rs:WP_029798096	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	81.3
rs:WP_021453706	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	81.3
rs:WP_043220818	DNA topoisomerase I [Pseudomonas balearica].	22.54	528	347	16	7	505	6	500	2e-12	81.3
rs:WP_005171670	DNA topoisomerase I [Gordonia aichiensis].	23.10	580	350	19	7	535	19	553	2e-12	81.3
tr:A0A0C1GX80_9NEIS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.35	538	313	19	7	505	28	510	2e-12	80.9
rs:WP_006275002	DNA topoisomerase I [Asticcacaulis biprosthecium].	23.82	550	324	23	4	510	1	498	2e-12	81.3
rs:WP_012101804	DNA topoisomerase I [Clostridium kluyveri].	23.87	532	314	22	7	504	6	480	2e-12	80.9
rs:WP_042958252	DNA topoisomerase, partial [Enterococcus faecium].	31.28	179	112	3	395	563	11	188	2e-12	79.3
rs:WP_022056000	DNA topoisomerase [Clostridium sp. CAG:167].	24.58	533	308	24	7	504	6	479	2e-12	80.9
rs:WP_044565945	DNA topoisomerase I [Anaerococcus sp. 9402080].	23.23	594	367	23	7	580	6	530	2e-12	80.9
rs:WP_031123959	DNA topoisomerase I [Streptomyces sp. NRRL S-623].	23.08	559	324	21	7	505	15	527	2e-12	81.3
rs:WP_024026822	DNA topoisomerase I [Bacillus vireti].	25.36	422	264	14	112	504	82	481	2e-12	80.9
tr:A0A0A5LGL4_AERHY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.75	538	340	16	7	505	6	501	2e-12	80.9
rs:WP_005457230	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_042857253	DNA topoisomerase III, partial [Staphylococcus aureus].	32.10	162	100	5	5	160	3	160	2e-12	76.6
rs:WP_041358070	DNA topoisomerase I [Nitrobacter hamburgensis].	23.51	536	331	20	4	505	1	491	2e-12	81.3
rs:WP_028394567	DNA topoisomerase I [Bacillus sp. FJAT-14578].	23.75	421	271	13	112	504	82	480	2e-12	80.9
rs:WP_031846489	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_025532763	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_026500741	DNA topoisomerase I [Bartonella grahamii].	24.46	552	308	27	4	505	1	493	2e-12	80.9
rs:WP_040163391	DNA topoisomerase I [bacterium SIT7].	22.86	560	334	19	7	505	9	531	2e-12	80.9
rs:WP_020493125	DNA topoisomerase I [Dehalobacter sp. FTH1].	24.07	536	321	22	3	505	2	484	2e-12	80.9
rs:WP_025794756	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_029485745	topoisomerase, partial [Enterococcus faecium].	38.84	121	64	5	5	121	3	117	2e-12	75.5
rs:WP_039489493	DNA topoisomerase I [Pectobacterium carotovorum].	26.13	444	270	20	88	505	88	499	2e-12	80.9
rs:WP_010154970	DNA topoisomerase I [Leucobacter chromiiresistens].	23.13	562	329	23	7	505	8	529	2e-12	81.3
rs:WP_011417280	DNA topoisomerase I [Syntrophus aciditrophicus].	22.84	521	320	18	47	510	21	516	2e-12	80.9
rs:WP_028632472	DNA topoisomerase I [Pseudomonas parafulva].	24.47	425	280	14	99	505	104	505	2e-12	80.9
rs:WP_000520428	topoisomerase I [Vibrio cholerae].	23.80	458	300	16	69	505	76	505	2e-12	80.9
rs:XP_011652538	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC101210823 [Cucumis sativus].	25.56	450	248	15	107	498	426	846	2e-12	81.3
rs:WP_021858644	DNA topoisomerase [Firmicutes bacterium CAG:83].	23.67	528	323	19	7	505	10	486	2e-12	80.9
rs:WP_015113376	DNA topoisomerase I [Nostoc sp. PCC 7107].	23.28	597	358	17	5	566	3	534	2e-12	80.9
rs:WP_025573646	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_025545701	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_004837937	hypothetical protein, partial [Anaerococcus tetradius].	33.55	155	89	5	266	417	4	147	2e-12	76.3
rs:WP_002245788	DNA topoisomerase I [Neisseria meningitidis].	24.62	532	319	19	7	505	6	488	2e-12	80.9
rs:WP_030881010	DNA topoisomerase I [Streptomyces sp. NRRL B-24051].	23.26	559	323	22	7	505	13	525	2e-12	80.9
rs:WP_017848775	topoisomerase I [Pseudomonas veronii].	22.52	453	313	13	69	505	75	505	2e-12	80.9
rs:WP_024875421	DNA topoisomerase I [Saccharomonospora sp. CNQ490].	23.55	552	334	20	7	505	21	537	2e-12	80.9
rs:WP_015577732	DNA topoisomerase I [Streptomyces sp. PAMC26508].	23.26	559	323	22	7	505	13	525	2e-12	80.9
rs:WP_009524712	DNA topoisomerase I [Peptostreptococcaceae bacterium ACC19a].	24.58	533	326	21	7	512	5	488	2e-12	80.9
rs:WP_033195612	DNA topoisomerase I, partial [Kushneria aurantia].	22.44	450	317	11	69	505	80	510	2e-12	80.9
rs:WP_015371522	DNA topoisomerase I subunit omega [Pseudomonas poae].	23.70	460	299	17	69	505	75	505	2e-12	80.9
rs:WP_012771455	topoisomerase I [Aggregatibacter aphrophilus].	24.55	444	277	16	88	505	93	504	2e-12	80.9
tr:C6SJC0_NEIME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.44	532	320	19	7	505	59	541	2e-12	80.9
rs:WP_008166223	topoisomerase I [Pseudoalteromonas sp. BSi20652].	22.25	454	313	13	69	505	77	507	2e-12	80.9
rs:WP_029851655	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_029559254	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_024699954	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_037021839	DNA topoisomerase I [Pseudomonas sp. 20_BN].	22.68	538	335	18	7	505	6	501	2e-12	80.9
rs:WP_027906767	DNA topoisomerase I [Pseudomonas taiwanensis].	22.72	537	339	19	7	505	6	504	2e-12	80.9
rs:WP_032758714	DNA topoisomerase I [Streptomyces alboviridis].	23.08	559	324	21	7	505	15	527	2e-12	80.9
rs:WP_013084804	DNA topoisomerase I [Bacillus megaterium].	24.47	421	268	13	112	504	82	480	2e-12	80.9
rs:WP_016751161	DNA topoisomerase I [Leptospira kirschneri].	24.57	529	315	20	1	505	1	469	2e-12	80.5
rs:WP_025577951	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_002249911	DNA topoisomerase I [Neisseria meningitidis].	25.40	433	268	15	107	505	77	488	2e-12	80.9
rs:WP_014203113	DNA topoisomerase I [Owenweeksia hongkongensis].	24.32	518	315	18	7	505	6	465	2e-12	80.9
rs:WP_029805460	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
tr:W0DWL7_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	24.19	525	323	22	7	515	4	469	2e-12	80.9
rs:WP_021461512	topoisomerase I [Gallibacterium anatis].	23.81	441	284	16	88	505	93	504	2e-12	80.9
rs:WP_006558567	DNA topoisomerase I [Acetobacter tropicalis].	23.69	553	320	24	7	510	5	504	2e-12	80.9
rs:WP_022240234	DNA topoisomerase [Clostridium sp. CAG:413].	24.06	532	319	21	7	505	5	484	2e-12	80.9
rs:WP_035153311	DNA topoisomerase I [Calothrix sp. 336/3].	24.72	538	310	17	89	583	72	557	2e-12	80.9
rs:WP_039135930	DNA topoisomerase I [Gallibacterium genomosp. 2].	23.81	441	284	16	88	505	93	504	2e-12	80.9
tr:A3QF42_SHELP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.78	419	266	16	107	505	130	523	2e-12	80.9
rs:WP_012334082	DNA topoisomerase I [Methylobacterium sp. 4-46].	23.78	555	322	24	4	510	1	502	2e-12	80.9
rs:WP_015609426	DNA topoisomerase I [Streptomyces fulvissimus].	23.08	559	324	21	7	505	15	527	2e-12	80.9
rs:WP_020840336	topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_025520612	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_046835583	DNA topoisomerase III, partial [Pseudomonas amygdali].	36.28	113	64	3	8	120	5	109	2e-12	75.5
rs:WP_019405754	topoisomerase I [Pseudomonas stutzeri].	22.04	540	337	18	7	505	6	502	2e-12	80.9
rs:WP_016500743	DNA topoisomerase I [Pseudomonas putida].	23.21	530	345	17	7	505	6	504	2e-12	80.9
rs:WP_029090988	DNA topoisomerase I [Brochothrix thermosphacta].	23.09	524	328	20	7	504	6	480	2e-12	80.5
rs:WP_017448270	topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_025554134	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_021687743	DNA topoisomerase I [Treponema lecithinolyticum].	24.20	529	315	22	7	505	18	490	2e-12	80.9
rs:WP_003714143	DNA topoisomerase I [Neisseria lactamica].	24.29	531	322	19	7	505	6	488	2e-12	80.9
rs:WP_023534198	DNA topoisomerase I [Pseudomonas putida].	22.87	529	348	17	7	505	6	504	2e-12	80.9
tr:M3TUR3_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.27	550	334	19	7	505	1	513	2e-12	80.9
rs:WP_025587383	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_033644711	DNA topoisomerase, partial [Enterococcus faecium].	31.28	179	112	3	395	563	10	187	2e-12	79.0
rs:WP_018127479	hypothetical protein [Balneola vulgaris].	24.59	549	323	24	7	505	5	512	2e-12	80.9
rs:WP_044128842	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_027885936	DNA topoisomerase I [Mesonia mobilis].	24.53	534	313	21	7	512	6	477	2e-12	80.9
rs:WP_010295184	topoisomerase I [Pectobacterium carotovorum].	25.28	443	275	18	88	505	88	499	2e-12	80.9
rs:WP_013448201	DNA topoisomerase I [Neisseria lactamica].	24.77	533	317	20	7	505	6	488	2e-12	80.9
rs:WP_004582047	DNA topoisomerase I subunit omega [Marinobacter nanhaiticus].	22.43	544	338	18	7	505	6	510	2e-12	80.9
tr:B9IVC2_BACCQ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.25	396	249	14	136	505	8	382	2e-12	80.5
rs:WP_013058887	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.47	421	268	13	112	504	82	480	2e-12	80.5
rs:WP_025629059	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_014412923	DNA topoisomerase I [Rickettsia australis].	24.68	547	320	22	7	510	4	501	2e-12	80.9
rs:WP_031416423	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_029838722	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_025557280	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_025534169	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_039473052	DNA topoisomerase I [Pectobacterium carotovorum].	26.13	444	270	20	88	505	88	499	2e-12	80.9
rs:WP_021945740	DNA topoisomerase [Clostridium sp. CAG:967].	22.88	555	353	19	88	607	72	586	2e-12	80.9
rs:WP_021627476	DNA topoisomerase I [Capnocytophaga sp. oral taxon 863].	22.14	515	327	15	7	504	6	463	2e-12	80.9
rs:WP_009632516	DNA topoisomerase I [Synechocystis sp. PCC 7509].	24.56	513	311	15	89	568	72	541	2e-12	80.9
rs:WP_025499340	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_019221809	DNA topoisomerase I [Bartonella senegalensis].	24.64	548	310	25	4	504	1	492	2e-12	80.9
rs:WP_041406645	DNA topoisomerase I [Shewanella loihica].	25.78	419	266	16	107	505	114	507	2e-12	80.9
rs:WP_025260740	DNA topoisomerase I [Pseudomonas cichorii].	22.81	456	308	13	69	505	75	505	2e-12	80.9
rs:WP_018118313	DNA topoisomerase I [Corynebacterium mastitidis].	25.11	462	276	17	97	505	88	532	2e-12	80.9
rs:WP_003385908	DNA topoisomerase I [Brevibacillus borstelensis].	23.81	525	327	20	5	504	4	480	2e-12	80.5
rs:WP_029480505	DNA topoisomerase I [Deinococcus marmoris].	24.64	621	345	25	3	568	2	554	2e-12	80.9
tr:L1MQG7_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.26	371	233	12	260	607	19	364	2e-12	80.1
rs:WP_040080846	DNA topoisomerase I [Mannheimia haemolytica].	24.22	450	290	16	79	505	83	504	2e-12	80.9
rs:WP_013931564	DNA topoisomerase I [Pseudothermotoga thermarum].	24.25	565	330	24	3	550	2	485	2e-12	80.5
rs:WP_018259862	DNA topoisomerase I [Methylobacterium sp. WSM2598].	23.78	555	322	24	4	510	1	502	2e-12	80.9
rs:WP_045542387	DNA topoisomerase I [Acetobacter tropicalis].	23.69	553	320	24	7	510	5	504	2e-12	80.9
rs:WP_014796302	DNA topoisomerase I [Flexibacter litoralis].	23.50	532	307	21	7	504	6	471	2e-12	80.9
rs:WP_029861698	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_030149446	DNA topoisomerase I [Mycetocola saprophilus].	24.04	549	329	24	7	506	8	517	2e-12	80.9
rs:WP_008545028	DNA topoisomerase I [Candidatus Pelagibacter sp. HTCC7211].	24.21	537	315	22	7	505	4	486	2e-12	80.9
rs:WP_024592543	DNA topoisomerase I [Pseudoalteromonas haloplanktis].	22.59	456	309	14	69	505	77	507	2e-12	80.9
rs:WP_007582594	topoisomerase I [Pseudoalteromonas sp. BSi20429].	22.59	456	309	14	69	505	77	507	2e-12	80.9
rs:WP_014714499	DNA topoisomerase I [Francisella noatunensis].	23.03	547	316	20	7	505	6	495	2e-12	80.5
rs:WP_013975679	topoisomerase I [Candidatus Moranella endobia].	22.77	527	337	18	7	505	6	490	2e-12	80.9
rs:WP_006251055	topoisomerase I [Mannheimia haemolytica].	24.22	450	290	16	79	505	83	504	2e-12	80.9
rs:WP_011143190	DNA topoisomerase I [Gloeobacter violaceus].	23.28	640	374	23	3	607	2	559	2e-12	80.5
rs:WP_033604845	DNA topoisomerase, partial [Enterococcus faecalis].	27.60	221	150	6	332	544	1	219	2e-12	79.3
rs:WP_017043915	topoisomerase I [Vibrio ordalii].	23.36	458	302	16	69	505	75	504	2e-12	80.9
rs:WP_029674661	DNA topoisomerase I [Butyrivibrio sp. VCB2006].	24.60	439	285	16	93	504	58	477	2e-12	80.5
rs:WP_024544176	DNA topoisomerase I [Mycoplasma salivarium].	24.38	525	310	23	92	586	65	532	2e-12	80.5
rs:WP_026518886	DNA topoisomerase I [Butyrivibrio sp. FCS006].	25.00	444	277	20	93	504	57	476	2e-12	80.5
rs:WP_030554443	DNA topoisomerase I [Streptomyces exfoliatus].	24.29	560	314	22	7	505	15	525	2e-12	80.9
rs:WP_022234894	DNA topoisomerase [Eubacterium sp. CAG:202].	24.86	523	304	22	7	498	5	469	2e-12	80.5
rs:WP_031556695	DNA topoisomerase I [Lachnospira multipara].	23.34	527	324	22	7	504	6	481	2e-12	80.5
rs:WP_042068216	DNA topoisomerase I ['Chrysanthemum coronarium' phytoplasma].	26.97	508	303	21	19	504	3	464	2e-12	80.5
rs:WP_029800337	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_015186585	DNA topoisomerase I [Gloeocapsa sp. PCC 7428].	24.22	516	306	15	89	566	72	540	2e-12	80.9
rs:WP_024983845	DNA topoisomerase I [Brevibacillus borstelensis].	23.81	525	327	20	5	504	4	480	2e-12	80.5
rs:WP_025612444	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_022394748	DNA topoisomerase [Coprobacillus sp. CAG:826].	25.12	434	280	14	93	504	64	474	2e-12	80.5
rs:WP_029864275	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_043917610	DNA topoisomerase I [Jannaschia aquimarina].	23.87	641	388	27	4	595	1	590	2e-12	80.9
rs:WP_043553201	DNA topoisomerase I, partial [Acetobacter malorum].	24.91	554	312	26	7	510	5	504	2e-12	80.9
sp:TOP1_SYNY3	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	23.27	550	322	19	91	603	74	560	2e-12	80.9
rs:WP_025796144	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_012152659	DNA topoisomerase I [Rickettsia massiliae].	23.81	546	326	23	7	510	4	501	2e-12	80.5
tr:M1ZR26_CLOBO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.52	154	102	3	279	428	18	170	2e-12	76.6
rs:WP_022095931	DNA topoisomerase [Clostridium sp. CAG:568].	22.87	634	381	24	7	607	4	562	2e-12	80.5
rs:WP_014414404	DNA topoisomerase I [Rhodospirillum photometricum].	25.82	550	300	26	7	505	4	496	2e-12	80.9
rs:WP_027437844	DNA topoisomerase I [Lachnospira multipara].	23.34	527	324	22	7	504	6	481	2e-12	80.5
rs:WP_008247632	topoisomerase I [gamma proteobacterium BDW918].	22.48	436	296	13	88	505	100	511	2e-12	80.9
rs:WP_029859090	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_029855921	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_043045652	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.9
rs:WP_010418604	DNA topoisomerase I [Leptospira inadai].	23.71	561	321	21	7	525	5	500	2e-12	80.5
rs:WP_021833112	DNA topoisomerase I [Crocosphaera watsonii].	24.79	468	280	17	93	512	1	444	2e-12	80.5
tr:K8B7E1_9ENTR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CCJ84182.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CCJ84182.1};	28.85	156	104	2	398	548	3	156	2e-12	77.4
rs:WP_039158618	DNA topoisomerase I [Gallibacterium anatis].	23.81	441	284	16	88	505	93	504	2e-12	80.9
rs:WP_039091086	DNA topoisomerase I [Gallibacterium anatis].	23.81	441	284	16	88	505	93	504	2e-12	80.9
rs:WP_029137196	DNA topoisomerase I [Nakamurella lactea].	24.14	555	327	23	7	504	14	531	2e-12	80.9
rs:WP_017049879	topoisomerase I [Vibrio ordalii].	23.19	457	304	16	69	505	75	504	2e-12	80.9
rs:WP_017044653	topoisomerase I [Vibrio ordalii].	23.36	458	302	16	69	505	75	504	2e-12	80.9
rs:WP_008724189	DNA topoisomerase I [Brachyspira hampsonii].	23.82	571	339	22	7	553	29	527	2e-12	80.5
rs:WP_021983662	GTP-sensing transcriptional pleiotropic repressor CodY [Eubacterium sp. CAG:603].	23.70	443	276	19	97	504	67	482	2e-12	80.5
rs:WP_002240958	DNA topoisomerase I [Neisseria meningitidis].	24.72	534	316	21	7	505	6	488	2e-12	80.5
rs:WP_003754393	DNA topoisomerase I [Neisseria polysaccharea].	24.67	531	320	18	7	505	6	488	2e-12	80.5
tr:I7L3U8_NEIME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.72	534	316	21	7	505	59	541	2e-12	80.5
rs:WP_041104016	DNA topoisomerase I [Burkholderia sp. 2385].	23.45	563	327	22	7	505	19	541	2e-12	80.9
tr:R4E063_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOM38168.1};	27.80	223	139	6	108	322	1	209	2e-12	77.4
rs:XP_006285818	hypothetical protein CARUB_v10007294mg [Capsella rubella].	26.44	522	300	23	47	510	499	994	2e-12	80.9
rs:WP_036866467	DNA topoisomerase I, partial [Prevotella melaninogenica].	25.74	237	153	5	4	232	2	223	2e-12	77.4
tr:A0A0D3A2X7_BRAOL	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo1g011520.1};	26.53	475	260	19	103	510	459	911	2e-12	80.9
rs:WP_036255616	DNA topoisomerase I [Methylocapsa acidiphila].	25.27	546	309	26	4	505	1	491	2e-12	80.9
rs:WP_018225554	DNA topoisomerase I [actinobacterium SCGC AAA044-N04].	23.58	564	331	23	4	510	9	529	2e-12	80.9
rs:WP_021740085	DNA topoisomerase I [Eubacterium ramulus].	24.38	443	279	17	93	504	63	480	2e-12	80.5
rs:WP_016421939	DNA topoisomerase I [Corynebacterium sp. HFH0082].	24.84	459	278	17	97	505	86	527	2e-12	80.9
rs:WP_009133961	DNA topoisomerase I [Alistipes indistinctus].	25.19	532	297	20	7	505	6	469	2e-12	80.5
rs:WP_039145862	DNA topoisomerase I [Gallibacterium anatis].	23.81	441	284	16	88	505	93	504	2e-12	80.5
tr:A0A087PLJ9_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.91	554	312	26	7	510	5	504	2e-12	80.5
gpu:CP009516_1332	DNA topoisomerase I [Methanosarcina horonobensis HB-1]	23.98	517	333	19	8	498	6	488	2e-12	80.5
rs:WP_013729133	topoisomerase I [Lactobacillus buchneri].	31.18	186	113	6	5	182	3	181	2e-12	76.6
gp:Z14112_1	DNA topoisomerase I [Bacillus firmus]	23.05	256	185	5	43	295	16	262	2e-12	77.4
rs:XP_008659455	PREDICTED: uncharacterized protein LOC103638270 isoform X3 [Zea mays].	25.71	529	319	19	36	513	317	822	2e-12	80.9
rs:WP_041139083	DNA topoisomerase I [Clostridiaceae bacterium GM1].	27.00	426	259	19	104	504	77	475	2e-12	80.5
rs:WP_045250685	DNA topoisomerase I [Microbacterium azadirachtae].	22.64	552	334	19	7	505	8	519	2e-12	80.5
rs:WP_011019972	topoisomerase IA [Methanopyrus kandleri].	22.40	558	360	19	7	545	11	514	2e-12	80.1
rs:WP_013455663	DNA topoisomerase I [Marivirga tractuosa].	24.57	521	312	18	7	505	6	467	2e-12	80.5
rs:WP_036491339	DNA topoisomerase I [Neisseria mucosa].	24.34	534	318	20	7	505	6	488	2e-12	80.5
rs:WP_016765407	DNA topoisomerase I [Bacillus megaterium].	24.47	421	268	13	112	504	82	480	2e-12	80.5
rs:WP_010128307	topoisomerase I [Haemophilus sputorum].	24.89	454	282	19	79	505	83	504	2e-12	80.5
rs:WP_014066714	DNA topoisomerase I [Rhodothermus marinus].	24.91	534	310	20	91	583	75	558	2e-12	80.5
rs:WP_020696273	hypothetical protein [Reyranella massiliensis].	22.75	545	325	19	4	505	1	492	2e-12	80.5
rs:WP_040176843	DNA topoisomerase I [Leuconostoc citreum].	24.38	525	317	22	7	504	28	499	2e-12	80.5
rs:WP_028410804	MULTISPECIES: DNA topoisomerase I [Bacillus].	24.47	421	268	13	112	504	82	480	2e-12	80.5
rs:WP_032850443	DNA topoisomerase I [Bacteroides sp. 1_1_14].	24.67	523	308	19	8	504	1	463	2e-12	80.5
rs:WP_035132778	DNA topoisomerase I [Clostridium sulfidigenes].	24.57	525	319	22	7	504	6	480	2e-12	80.5
rs:XP_001739303	DNA topoisomerase 3-alpha [Entamoeba dispar SAW760].	23.56	450	306	13	91	532	96	515	2e-12	80.1
tr:T0L751_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.20	533	317	22	7	504	13	493	2e-12	80.5
rs:WP_016670597	DNA topoisomerase I [Neisseria meningitidis].	24.72	534	316	21	7	505	6	488	2e-12	80.5
rs:WP_002257107	DNA topoisomerase I [Neisseria meningitidis].	24.62	532	319	19	7	505	6	488	2e-12	80.5
rs:WP_002216226	DNA topoisomerase I [Neisseria meningitidis].	24.72	534	316	21	7	505	6	488	2e-12	80.5
rs:WP_012532572	type I DNA topoisomerase TopA [Rhodococcus equi].	24.89	446	273	19	7	425	3	413	2e-12	80.5
rs:WP_036471856	DNA topoisomerase I [Mycobacterium triplex].	25.48	467	283	17	86	504	84	533	2e-12	80.5
rs:WP_029834336	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	23.41	457	303	16	69	505	4	433	2e-12	80.5
tr:J9DEH1_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.58	547	327	21	7	510	4	502	2e-12	80.5
rs:WP_039605753	DNA topoisomerase I [Pseudomonas tuomuerensis].	22.28	534	343	17	7	505	6	502	2e-12	80.5
rs:WP_039096786	DNA topoisomerase I [Gallibacterium anatis].	23.81	441	284	16	88	505	93	504	2e-12	80.5
rs:WP_039089898	DNA topoisomerase I [Gallibacterium anatis].	23.81	441	284	16	88	505	93	504	2e-12	80.5
rs:WP_012329483	DNA topoisomerase I [Methylobacterium radiotolerans].	23.76	526	326	19	97	591	74	555	2e-12	80.5
rs:WP_028669069	DNA topoisomerase I [Runella zeae].	22.92	528	312	18	7	505	6	467	2e-12	80.5
rs:WP_006249032	topoisomerase I [Mannheimia haemolytica].	24.37	439	283	15	88	505	94	504	2e-12	80.5
rs:WP_041437548	DNA topoisomerase I, partial [Synechococcus sp. JA-2-3B'a(2-13)].	23.39	560	342	18	46	566	29	540	2e-12	80.5
rs:WP_008094100	topoisomerase I [Pseudomonas sp. GM84].	23.83	428	279	14	99	505	104	505	2e-12	80.5
tr:A0A094QAU3_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KGA21365.1};	24.79	597	323	25	7	550	14	537	2e-12	80.5
rs:WP_017047729	topoisomerase I [Vibrio ordalii].	23.36	458	302	16	69	505	75	504	2e-12	80.5
rs:WP_025508709	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	2e-12	80.5
rs:XP_008659453	PREDICTED: uncharacterized protein LOC103638270 isoform X1 [Zea mays].	25.67	526	317	19	36	510	317	819	2e-12	80.9
rs:WP_003749245	DNA topoisomerase I [Neisseria mucosa].	24.62	532	319	19	7	505	6	488	2e-12	80.5
rs:WP_002639752	DNA topoisomerase I [Myxococcus sp. (contaminant ex DSM 436)].	24.06	478	288	18	93	516	140	596	2e-12	80.5
tr:G1XWN3_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.95	541	309	24	8	505	1	487	2e-12	80.5
rs:WP_019281959	topoisomerase I [Vibrio anguillarum].	23.30	455	306	15	69	505	75	504	2e-12	80.5
rs:WP_021951438	DNA topoisomerase [Clostridium sp. CAG:678].	26.13	444	266	20	97	505	66	482	2e-12	80.5
rs:WP_016688293	DNA topoisomerase I [Neisseria sicca].	24.44	540	310	21	7	505	6	488	2e-12	80.5
rs:WP_020294130	DNA topoisomerase I [Pseudomonas sp. CFII64].	23.25	456	306	14	69	505	75	505	2e-12	80.5
rs:WP_034053622	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	31.47	143	83	2	423	552	4	144	2e-12	77.0
rs:WP_025627646	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	23.75	459	299	18	69	505	34	463	2e-12	80.5
rs:WP_022853525	DNA topoisomerase I [Thermodesulfatator atlanticus].	24.63	540	325	19	7	516	6	493	2e-12	80.5
rs:WP_011057718	DNA topoisomerase I [Thermosynechococcus elongatus].	24.01	558	329	21	5	510	3	517	2e-12	80.5
rs:WP_044396592	DNA topoisomerase I [Bacillus subterraneus].	23.53	527	322	19	7	504	6	480	2e-12	80.1
rs:WP_022072993	DNA topoisomerase [Anaerotruncus sp. CAG:528].	24.49	535	311	21	7	505	5	482	2e-12	80.1
rs:WP_041438846	DNA topoisomerase I, partial [Synechococcus sp. JA-3-3Ab].	23.05	512	311	15	91	566	74	538	2e-12	80.5
tr:T0ZSF8_9ZZZZ	SubName: Full=DNA topoisomerase III beta {ECO:0000313|EMBL:EQD51221.1}; Flags: Fragment;	26.44	329	209	12	102	420	98	403	2e-12	79.3
rs:WP_014892639	DNA topoisomerase I [Methylocystis sp. SC2].	24.28	556	318	24	4	510	1	502	2e-12	80.5
rs:WP_038300223	DNA topoisomerase I, partial [alpha proteobacterium IMCC14465].	23.77	547	326	21	7	510	4	502	2e-12	80.5
rs:WP_017613841	DNA topoisomerase I [Nocardiopsis salina].	23.54	548	335	20	7	505	26	538	2e-12	80.5
tr:R3QFQ2_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOL03019.1}; Flags: Fragment;	31.61	174	110	5	379	544	36	208	2e-12	78.6
rs:WP_013922222	DNA topoisomerase I [Francisella sp. TX077308].	23.63	546	314	21	7	505	6	495	2e-12	80.5
rs:WP_018295093	DNA topoisomerase I [Mariprofundus ferrooxydans].	24.38	562	324	23	1	515	1	508	2e-12	80.5
rs:XP_003868447	Top3 protein [Candida orthopsilosis Co 90-125].	24.07	644	380	29	7	595	3	592	2e-12	80.1
rs:WP_035192062	DNA topoisomerase I, partial [Acidithiobacillus ferrivorans].	25.96	366	199	12	7	347	6	324	2e-12	79.3
rs:WP_019226964	MULTISPECIES: DNA topoisomerase I [Clostridiales].	25.86	526	313	22	7	504	5	481	2e-12	80.5
tr:E3D5G6_NEIM7	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.62	532	319	19	7	505	59	541	2e-12	80.5
rs:WP_026003064	DNA topoisomerase I [Rhodococcus sp. R1101].	24.02	587	349	22	7	550	19	551	2e-12	80.5
rs:WP_023801090	DNA topoisomerase I [Mesorhizobium sp. L48C026A00].	24.63	544	316	22	4	505	1	492	2e-12	80.5
tr:F5YSD3_MYCSD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.97	509	306	17	86	550	69	540	2e-12	80.5
rs:WP_024543326	DNA topoisomerase I [actinobacterium SCGC AAA044-D11].	24.04	549	327	20	7	505	6	514	2e-12	80.5
rs:WP_035369177	DNA topoisomerase I [Acholeplasma hippikon].	23.81	609	372	25	26	607	12	555	2e-12	80.1
rs:WP_027122666	DNA topoisomerase I [Mycoplasma spumans].	22.91	515	325	19	7	504	6	465	2e-12	80.1
rs:WP_014410571	DNA topoisomerase I [Rickettsia parkeri].	24.18	546	324	23	7	510	4	501	2e-12	80.5
rs:WP_022894038	DNA topoisomerase I [Agromyces subbeticus].	23.85	566	324	22	7	505	8	533	2e-12	80.5
tr:A0A0B0EM62_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.42	521	320	16	7	505	6	469	2e-12	80.5
rs:WP_002220143	DNA topoisomerase I [Neisseria meningitidis].	24.72	534	316	21	7	505	6	488	2e-12	80.5
rs:WP_044927185	DNA topoisomerase I, partial [Roseburia inulinivorans].	23.93	443	282	18	93	504	63	481	2e-12	80.1
rs:WP_027310435	DNA topoisomerase I [Bacteroidetes bacterium SCGC AAA027-N21].	23.99	521	310	20	7	504	6	463	3e-12	80.5
rs:WP_006575107	DNA topoisomerase I [Pseudoflavonifractor capillosus].	21.91	534	338	19	1	505	1	484	3e-12	80.5
rs:WP_031556969	DNA topoisomerase I [Lachnospiraceae bacterium FD2005].	24.29	527	320	25	7	504	6	482	3e-12	80.1
rs:WP_044642672	DNA topoisomerase I [Thermoactinomycetaceae bacterium GD1].	25.53	427	266	14	107	504	77	480	3e-12	80.1
rs:WP_022657618	DNA topoisomerase I [Desulfovibrio desulfuricans].	25.86	437	283	15	91	505	61	478	3e-12	80.1
rs:WP_031482315	DNA topoisomerase I [Desulfovibrio frigidus].	22.89	546	317	19	7	510	6	489	3e-12	80.5
rs:XP_006382211	hypothetical protein POPTR_0006s29400g [Populus trichocarpa].	25.05	511	304	21	47	505	336	819	3e-12	80.5
rs:WP_002079051	DNA topoisomerase I [Leptospira interrogans].	24.04	520	317	19	7	504	5	468	3e-12	80.1
rs:WP_026960310	DNA topoisomerase I [Aliagarivorans taiwanensis].	24.25	466	291	17	69	505	75	507	3e-12	80.5
rs:WP_040361669	DNA topoisomerase I [Corynebacterium amycolatum].	25.22	460	275	18	97	505	86	527	3e-12	80.5
rs:WP_002250953	DNA topoisomerase I [Neisseria meningitidis].	24.62	532	319	19	7	505	6	488	3e-12	80.1
rs:WP_045324926	DNA topoisomerase I [Vibrio parahaemolyticus].	23.75	459	299	18	69	505	83	512	3e-12	80.5
rs:WP_005786156	topoisomerase I [Pseudomonas synxantha].	22.44	459	306	14	69	505	75	505	3e-12	80.5
rs:WP_000520425	topoisomerase I [Vibrio cholerae].	24.02	458	299	16	69	505	76	505	3e-12	80.5
rs:WP_045797271	DNA topoisomerase I [Orientia chuto].	25.24	531	314	24	7	504	4	484	3e-12	80.5
rs:WP_043670276	DNA topoisomerase I [Clavibacter michiganensis].	22.50	551	335	18	7	505	8	518	3e-12	80.5
rs:WP_045935848	DNA topoisomerase I [Bifidobacterium asteroides].	22.70	555	329	22	7	505	8	518	3e-12	80.5
rs:WP_029220880	DNA topoisomerase I [Xanthomonas cassavae].	23.98	488	317	19	43	505	25	483	3e-12	80.5
rs:WP_010423404	DNA topoisomerase I [Rickettsia helvetica].	23.63	546	327	22	7	510	4	501	3e-12	80.1
rs:WP_005703159	topoisomerase I [Aggregatibacter aphrophilus].	24.55	444	277	16	88	505	93	504	3e-12	80.5
rs:WP_034118691	DNA topoisomerase I [Pseudomonas fluorescens].	22.44	459	306	14	69	505	75	505	3e-12	80.5
rs:WP_017129593	topoisomerase I [Pseudomonas gingeri].	23.09	459	303	15	69	505	75	505	3e-12	80.5
rs:WP_002224768	DNA topoisomerase I [Neisseria meningitidis].	24.72	534	316	21	7	505	6	488	3e-12	80.1
rs:WP_014392084	DNA topoisomerase I [Candidatus Rickettsia amblyommii].	25.11	454	283	17	97	510	65	501	3e-12	80.1
tr:Q2JWS9_SYNJA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.05	512	311	15	91	566	74	538	3e-12	80.5
rs:WP_008862920	DNA topoisomerase I [Barnesiella intestinihominis].	24.06	532	298	20	7	504	6	465	3e-12	80.1
rs:WP_041319014	DNA topoisomerase I [Mycobacterium sp. JDM601].	23.97	509	306	17	86	550	79	550	3e-12	80.5
rs:WP_026515776	DNA topoisomerase I [Butyrivibrio sp. MC2021].	24.60	443	280	20	93	504	57	476	3e-12	80.1
rs:WP_032877218	DNA topoisomerase I [Pseudomonas sp. BRG-100].	22.44	459	306	14	69	505	75	505	3e-12	80.5
rs:WP_000520427	topoisomerase I [Vibrio cholerae].	24.02	458	299	16	69	505	76	505	3e-12	80.5
rs:WP_002218552	DNA topoisomerase I [Neisseria meningitidis].	24.62	532	319	19	7	505	6	488	3e-12	80.1
tr:D4LFQ5_9FIRM	SubName: Full=Draft genome {ECO:0000313|EMBL:CBL18666.1};	28.84	215	121	7	7	212	5	196	3e-12	78.6
rs:WP_002987636	MULTISPECIES: DNA topoisomerase I [Myroides].	23.45	516	319	18	7	504	6	463	3e-12	80.5
rs:WP_043215225	DNA topoisomerase I [Pseudomonas putida].	25.16	477	296	17	97	555	75	508	3e-12	80.1
rs:WP_009622375	DNA topoisomerase I [Desulfosporosinus sp. OT].	25.72	591	322	28	3	555	2	513	3e-12	80.1
tr:D5HI49_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.42	538	309	24	7	504	20	494	3e-12	80.1
rs:WP_005758915	topoisomerase I [Pasteurella bettyae].	24.55	444	277	16	88	505	93	504	3e-12	80.5
rs:WP_010230372	DNA topoisomerase I [Gillisia marina].	25.38	528	296	22	7	505	6	464	3e-12	80.1
rs:WP_013857079	topoisomerase I [Vibrio anguillarum].	23.19	457	304	16	69	505	75	504	3e-12	80.5
rs:WP_045586691	DNA topoisomerase I [Vibrio parahaemolyticus].	22.61	544	331	21	7	505	6	504	3e-12	80.5
tr:X0ZH22_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_C00245 {ECO:0000313|EMBL:GAG68624.1};	23.39	342	228	8	203	540	1	312	3e-12	79.7
rs:WP_039531544	DNA topoisomerase I [Pectobacterium carotovorum].	26.13	444	270	20	88	505	88	499	3e-12	80.5
rs:WP_002242228	DNA topoisomerase I [Neisseria meningitidis].	24.62	532	319	19	7	505	6	488	3e-12	80.1
rs:WP_012722846	topoisomerase I [Pseudomonas fluorescens].	22.44	459	306	14	69	505	75	505	3e-12	80.5
rs:WP_013859077	DNA topoisomerase I [Bacillus coagulans].	24.82	419	269	14	112	504	82	480	3e-12	80.1
tr:A0A0E0M300_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC09G13790.1};	23.34	527	343	19	1	498	1	495	3e-12	80.1
tr:I4E2V2_NEIME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.72	534	316	21	7	505	59	541	3e-12	80.1
rs:XP_662159	hypothetical protein AN4555.2 [Aspergillus nidulans FGSC A4].	23.06	594	359	21	5	555	4	542	3e-12	80.1
rs:WP_011919438	topoisomerase I [Shewanella putrefaciens].	23.35	544	330	19	7	505	6	507	3e-12	80.1
rs:WP_044976306	DNA topoisomerase I [Ruminococcus sp. HUN007].	24.86	535	310	21	7	505	5	483	3e-12	80.1
tr:A0A0E2KMW4_VIBPH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQM48978.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EQM48978.1};	23.75	459	299	18	69	505	68	497	3e-12	80.1
rs:WP_029657274	hypothetical protein, partial [Enterococcus faecalis].	39.67	121	63	5	5	121	3	117	3e-12	74.7
rs:WP_039204962	DNA topoisomerase I [Aphanizomenon flos-aquae].	23.66	448	285	15	91	505	66	489	3e-12	80.1
rs:WP_043827116	DNA topoisomerase I [Amycolatopsis orientalis].	23.60	555	327	20	7	505	22	535	3e-12	80.5
rs:WP_037808332	DNA topoisomerase I [Streptomyces sp. NRRL F-3213].	23.60	555	327	20	7	505	22	535	3e-12	80.5
rs:WP_040243726	DNA topoisomerase I [Chromohalobacter japonicus].	22.28	534	352	16	7	505	6	511	3e-12	80.1
rs:WP_043900714	hypothetical protein, partial [Parcubacteria bacterium RAAC4_OD1_1].	22.85	582	340	23	7	557	4	507	3e-12	80.1
rs:WP_047309161	DNA topoisomerase I [Rhodopseudomonas palustris].	25.37	540	311	22	7	505	4	492	3e-12	80.5
rs:WP_045800259	DNA topoisomerase I [Candidatus Rickettsia amblyommii].	25.11	454	283	17	97	510	65	501	3e-12	80.1
rs:WP_031058622	DNA topoisomerase I [Streptomyces ochraceiscleroticus].	25.00	460	271	18	97	505	91	527	3e-12	80.5
rs:WP_003686257	DNA topoisomerase I [Neisseria flavescens].	24.62	532	319	19	7	505	6	488	3e-12	80.1
rs:WP_002234458	DNA topoisomerase I [Neisseria meningitidis].	24.72	534	316	21	7	505	6	488	3e-12	80.1
tr:A0A069D168_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.57	524	304	21	7	504	6	469	3e-12	80.1
rs:WP_020805371	toprim domain protein, partial [Klebsiella pneumoniae].	28.50	207	135	5	7	210	4	200	3e-12	76.6
rs:WP_009186409	DNA topoisomerase I [Cecembia lonarensis].	22.96	527	313	17	7	505	6	467	3e-12	80.1
rs:WP_034649196	DNA topoisomerase I [Bacillus megaterium].	24.47	421	268	13	112	504	82	480	3e-12	80.1
rs:WP_007797415	DNA topoisomerase I [Pelagibaca bermudensis].	24.63	471	273	20	4	449	1	414	3e-12	80.1
rs:WP_012844201	DNA topoisomerase I [Rhodothermus marinus].	24.91	534	310	20	91	583	75	558	3e-12	80.1
rs:WP_025732923	DNA topoisomerase I [Carnimonas nigrificans].	24.37	439	282	16	88	505	97	506	3e-12	80.1
rs:WP_016391296	DNA topoisomerase I subunit omega [Pseudomonas plecoglossicida].	23.60	428	280	14	99	505	104	505	3e-12	80.1
rs:WP_010900394	type 1 DNA topoisomerase-like protein, partial [Rhodococcus equi].	24.50	449	271	19	7	425	38	448	3e-12	79.3
rs:WP_027110232	DNA topoisomerase I [Lachnospiraceae bacterium NC2008].	23.54	531	318	24	7	504	6	481	3e-12	80.1
rs:WP_021901316	DNA topoisomerase [Coprobacillus sp. CAG:698].	24.26	437	284	15	93	506	66	478	3e-12	80.1
rs:WP_005781823	DNA topoisomerase I [Bacteroides fragilis].	23.70	595	353	24	7	564	6	536	3e-12	80.1
rs:WP_032863314	DNA topoisomerase I [Pseudomonas sp. FH4].	22.37	456	310	13	69	505	75	505	3e-12	80.1
rs:WP_039730782	DNA topoisomerase III, partial [Enterococcus mundtii].	28.87	194	124	5	41	232	1	182	3e-12	76.6
rs:WP_035335751	DNA topoisomerase I [Dokdonia sp. PRO95].	25.28	538	304	23	7	512	6	477	3e-12	80.1
rs:WP_035040032	DNA topoisomerase I [Catonella morbi].	21.97	528	329	19	7	504	6	480	3e-12	80.1
rs:WP_004812098	DNA topoisomerase I [Anaerococcus hydrogenalis].	22.92	624	382	27	7	603	6	557	3e-12	80.1
rs:WP_039166606	DNA topoisomerase I [Gallibacterium anatis].	23.81	441	284	16	88	505	93	504	3e-12	80.1
rs:WP_017603757	DNA topoisomerase I [Nocardiopsis alkaliphila].	23.83	554	325	22	7	505	26	537	3e-12	80.1
rs:WP_038526951	DNA topoisomerase I [Formosa agariphila].	25.43	523	300	23	7	504	6	463	3e-12	80.1
rs:WP_012422574	DNA topoisomerase I [Borrelia hermsii].	23.70	595	354	24	7	561	7	541	3e-12	80.1
tr:E2MXW7_CORAY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.22	460	275	18	97	505	132	573	3e-12	80.5
tr:Q2JJ84_SYNJB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.39	560	342	18	46	566	29	540	3e-12	80.1
rs:WP_030169091	MULTISPECIES: DNA topoisomerase I [Actinomycetales].	23.87	553	327	21	7	505	19	531	3e-12	80.1
rs:WP_003677938	DNA topoisomerase I [Neisseria cinerea].	24.86	539	309	22	7	505	6	488	3e-12	80.1
rs:WP_024074081	topoisomerase I [Pseudomonas sp. TKP].	22.44	459	306	14	69	505	75	505	3e-12	80.1
rs:WP_021996854	DNA topoisomerase [Clostridium sp. CAG:780].	23.34	527	324	18	7	504	6	481	3e-12	80.1
rs:WP_009064086	DNA topoisomerase I [Clostridium sp. JCD].	23.97	580	329	23	7	553	5	505	3e-12	80.1
rs:WP_038088810	DNA topoisomerase I [Tumebacillus flagellatus].	23.26	533	329	21	1	504	1	482	3e-12	80.1
rs:WP_034172188	DNA topoisomerase I [Chrysanthemum yellows phytoplasma].	26.97	508	303	21	19	504	3	464	3e-12	79.7
rs:WP_016548180	DNA topoisomerase I [Leptospira fainei].	23.79	559	323	22	7	525	5	500	3e-12	79.7
rs:WP_036873431	DNA topoisomerase I, partial [Prevotella maculosa].	27.07	229	145	5	4	224	1	215	3e-12	76.6
tr:X1WUB7_ACYPI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.96	416	241	18	119	505	103	480	3e-12	79.7
rs:WP_034781453	hypothetical protein, partial [Bacteroides graminisolvens].	25.57	524	304	21	7	504	6	469	3e-12	80.1
tr:A0A096SY28_MAIZE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.11	380	229	13	36	390	260	616	3e-12	79.7
rs:WP_043188271	DNA topoisomerase I [Pseudomonas rhizosphaerae].	24.12	427	279	14	99	505	104	505	3e-12	80.1
rs:WP_024226552	hypothetical protein, partial [Escherichia coli].	30.88	204	118	5	364	546	22	223	3e-12	77.4
rs:WP_040370877	DNA topoisomerase I [Desulfovibrio alkalitolerans].	23.32	536	322	18	7	505	6	489	3e-12	80.1
rs:WP_046163817	DNA topoisomerase I [Pseudomonas sp. 10B238].	22.16	537	340	18	7	505	6	502	3e-12	80.1
rs:WP_003349030	DNA topoisomerase I [Bacillus methanolicus].	25.06	419	268	13	112	504	82	480	3e-12	79.7
rs:WP_021922657	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia inulinivorans CAG:15].	23.93	443	282	18	93	504	63	481	3e-12	79.7
rs:WP_003707115	DNA topoisomerase I [Neisseria lactamica].	24.86	531	319	19	7	505	6	488	3e-12	80.1
rs:WP_002224383	DNA topoisomerase I [Neisseria meningitidis].	24.62	532	319	19	7	505	6	488	3e-12	80.1
rs:WP_030564994	DNA topoisomerase I [Streptomyces cyaneofuscatus].	23.08	559	324	21	7	505	15	527	3e-12	80.1
rs:WP_003297053	DNA topoisomerase I subunit omega [Pseudomonas stutzeri].	22.76	435	296	12	88	505	91	502	3e-12	80.1
rs:WP_023720102	DNA topoisomerase I [Mesorhizobium sp. LSHC420B00].	25.09	550	306	24	4	505	1	492	3e-12	80.1
rs:WP_035020929	DNA topoisomerase I [Anoxybacillus flavithermus].	23.91	527	312	22	112	598	82	559	3e-12	79.7
rs:WP_014356315	DNA topoisomerase I [Acetobacterium woodii].	24.51	461	283	17	92	515	62	494	3e-12	79.7
tr:C3DNN3_BACTS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.64	390	242	16	143	505	5	373	3e-12	79.7
tr:R4FEZ4_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.91	527	312	22	112	598	83	560	3e-12	79.7
rs:XP_008466640	PREDICTED: uncharacterized protein LOC103503996, partial [Cucumis melo].	27.66	329	190	12	47	347	308	616	3e-12	79.7
rs:WP_014365975	DNA topoisomerase I [Rickettsia massiliae].	23.81	546	326	23	7	510	4	501	3e-12	80.1
rs:WP_021114792	DNA topoisomerase I [Haemophilus parasuis].	23.57	454	288	18	79	505	85	506	3e-12	80.1
tr:C6SEJ0_NEIME	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.44	532	320	19	7	505	59	541	3e-12	80.1
rs:WP_043047499	DNA topoisomerase I [Pseudomonas fluorescens].	22.44	459	306	14	69	505	75	505	3e-12	80.1
rs:WP_027604240	DNA topoisomerase I [Pseudomonas sp. LAMO17WK12:I2].	22.44	459	306	14	69	505	75	505	3e-12	80.1
rs:WP_025791947	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	3e-12	80.1
rs:WP_014610724	topoisomerase I [Shewanella putrefaciens].	23.35	544	330	19	7	505	6	507	3e-12	80.1
tr:H5SLA0_9CHLR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.08	544	308	24	7	504	26	510	3e-12	79.7
rs:WP_037550502	DNA topoisomerase I [Spirochaeta sp. JC230].	23.36	548	341	16	1	505	1	512	3e-12	80.1
rs:WP_027748357	DNA topoisomerase I [Streptomyces sp. CNH287].	24.89	462	273	17	97	505	90	530	3e-12	80.1
rs:WP_040332936	DNA topoisomerase I, partial [Butyricicoccus pullicaecorum].	24.77	537	314	21	7	505	5	489	3e-12	79.7
rs:WP_017526655	topoisomerase I [Pseudomonas fluorescens].	22.44	459	306	14	69	505	75	505	3e-12	80.1
rs:WP_043945779	DNA topoisomerase III, partial [Carnobacterium sp. WN1359].	30.86	175	112	3	387	555	6	177	3e-12	78.2
tr:S4NCT1_9PORP	SubName: Full=DNA topoisomerase III, Bacteroidales-type {ECO:0000313|EMBL:GAD06918.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAD06918.1};	27.09	251	155	7	4	243	1	234	3e-12	77.0
gpu:CP009511_1054	DNA topoisomerase I [Methanosarcina mazei SarPi]	23.84	516	335	19	8	498	6	488	3e-12	80.1
rs:WP_005780640	topoisomerase I [Pseudomonas amygdali].	22.81	456	308	13	69	505	75	505	3e-12	80.1
rs:WP_030035662	DNA topoisomerase I [Clostridium botulinum].	25.50	549	316	24	7	517	6	499	3e-12	79.7
rs:WP_026666020	DNA topoisomerase I [Butyrivibrio sp. FC2001].	24.32	444	282	19	93	505	66	486	3e-12	79.7
rs:WP_039403381	DNA topoisomerase I, partial [Microbacterium mangrovi].	23.24	611	365	23	7	579	12	556	3e-12	80.1
rs:WP_041350251	DNA topoisomerase I [Clostridium botulinum].	25.14	549	318	23	7	517	6	499	3e-12	79.7
rs:WP_010563749	topoisomerase I [Pseudomonas extremaustralis].	22.44	459	306	14	69	505	75	505	3e-12	80.1
rs:WP_046384322	DNA topoisomerase I [Pseudomonas veronii].	22.44	459	306	14	69	505	75	505	3e-12	80.1
rs:WP_022863555	DNA topoisomerase I [Corynebacterium massiliense].	25.46	546	304	26	40	510	32	549	3e-12	80.1
tr:V5GTF2_IXORI	SubName: Full=Putative dna topoisomerase iii alpha {ECO:0000313|EMBL:JAB73695.1}; Flags: Fragment;	23.22	478	288	18	107	553	111	540	3e-12	80.1
rs:WP_027291047	DNA topoisomerase I [Rikenella microfusus].	23.83	533	304	22	7	504	6	471	3e-12	80.1
rs:WP_011160653	topoisomerase I [Onion yellows phytoplasma].	26.97	508	303	21	19	504	3	464	3e-12	79.7
rs:WP_014197383	DNA topoisomerase I [Azospirillum brasilense].	24.68	547	317	22	1	505	1	494	3e-12	80.1
rs:WP_015496188	DNA topoisomerase I [Octadecabacter arcticus].	24.77	549	317	25	4	510	1	495	3e-12	80.1
rs:WP_004996071	DNA topoisomerase I [Rickettsia sibirica].	24.18	546	324	23	7	510	4	501	3e-12	79.7
rs:WP_039086764	DNA topoisomerase I [Gallibacterium anatis].	23.81	441	284	16	88	505	93	504	3e-12	80.1
rs:WP_028934170	DNA topoisomerase I [Pseudonocardia spinosispora].	23.61	559	337	21	7	510	42	565	3e-12	80.1
rs:XP_005848029	hypothetical protein CHLNCDRAFT_145197 [Chlorella variabilis].	24.28	416	238	15	5	400	91	449	3e-12	80.1
rs:WP_000520426	topoisomerase I [Vibrio cholerae].	24.02	458	299	16	69	505	76	505	3e-12	80.1
rs:WP_016926149	DNA topoisomerase I [Rickettsia conorii].	24.18	546	324	22	7	510	4	501	3e-12	79.7
tr:A0A0D6NPJ8_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN68032.1};	24.64	556	311	27	7	510	5	504	3e-12	80.1
tr:T0CZ37_CLOSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	30.62	209	115	7	213	408	1	192	3e-12	76.3
rs:WP_012692721	DNA topoisomerase I [Deinococcus deserti].	23.34	617	349	25	5	568	4	549	4e-12	80.1
rs:WP_034919220	DNA topoisomerase I [Gillisia sp. CAL575].	25.38	528	294	22	7	504	6	463	4e-12	80.1
rs:WP_036204645	DNA topoisomerase I [Megasphaera elsdenii].	22.85	534	322	22	7	504	59	538	4e-12	79.7
rs:WP_039737107	DNA topoisomerase I [Hassallia byssoidea].	23.08	598	358	17	5	566	3	534	4e-12	80.1
tr:V2XKU8_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.97	528	329	19	7	504	8	482	4e-12	79.7
rs:WP_035316934	DNA topoisomerase I [Clostridium sp. MSTE9].	23.97	580	329	23	7	553	14	514	4e-12	79.7
tr:F2RAB3_STRVP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.11	560	315	22	7	505	51	561	4e-12	80.1
rs:WP_005963182	DNA topoisomerase TopA [Actinomyces cardiffensis].	21.89	571	332	21	1	505	1	523	4e-12	80.1
rs:WP_005700469	topoisomerase I [Aggregatibacter aphrophilus].	24.55	444	277	16	88	505	93	504	4e-12	80.1
rs:WP_013701770	DNA topoisomerase I [Treponema succinifaciens].	24.81	532	310	23	5	504	18	491	4e-12	79.7
rs:WP_011200271	topoisomerase I [[Mannheimia] succiniciproducens].	24.37	439	284	16	88	505	93	504	4e-12	80.1
gp:AM902716_1304	pseudogene [Bordetella petrii]	34.46	148	82	3	418	552	1	146	4e-12	77.0
rs:WP_039683440	DNA topoisomerase I [Deinococcus swuensis].	24.51	616	347	25	3	568	2	549	4e-12	80.1
rs:WP_040190181	DNA topoisomerase I [Leuconostoc citreum].	24.39	529	312	22	7	504	28	499	4e-12	79.7
rs:WP_023634013	DNA topoisomerase I [Geobacillus sp. MAS1].	23.11	623	379	22	7	598	6	559	4e-12	79.7
rs:WP_016945597	DNA topoisomerase I [Rickettsia conorii].	24.18	546	324	22	7	510	4	501	4e-12	79.7
rs:WP_007060088	DNA topoisomerase I [Clostridium carboxidivorans].	24.58	541	331	18	7	517	6	499	4e-12	79.7
rs:WP_032807126	topoisomerase I, partial [Oenococcus oeni].	31.18	186	113	6	5	182	3	181	4e-12	76.3
rs:WP_036513036	DNA topoisomerase I [Oceanicaulis sp. HL-87].	23.70	557	317	23	4	510	1	499	4e-12	79.7
rs:WP_033910279	DNA topoisomerase I [Neisseria gonorrhoeae].	24.48	531	321	18	7	505	6	488	4e-12	79.7
tr:I9XBE8_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	29.30	215	128	7	308	505	14	221	4e-12	79.0
rs:WP_002259562	DNA topoisomerase I [Neisseria meningitidis].	24.62	532	319	19	7	505	6	488	4e-12	79.7
tr:A0A0D6AJC9_9CHRO	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:BAQ62928.1};	23.85	545	330	19	5	505	3	506	4e-12	79.7
rs:WP_046932464	DNA topoisomerase I [Xanthomonas perforans].	23.98	488	317	19	43	505	25	483	4e-12	79.7
rs:WP_004899760	DNA topoisomerase I [Leuconostoc citreum].	24.39	529	312	22	7	504	28	499	4e-12	79.7
rs:WP_015410922	DNA topoisomerase I [Methanosarcina mazei].	23.84	516	335	19	8	498	6	488	4e-12	79.7
rs:WP_036280765	DNA topoisomerase I [Methylocystis sp. ATCC 49242].	24.90	526	305	25	34	510	18	502	4e-12	79.7
rs:XP_008393933	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X2 [Malus domestica].	25.59	422	238	16	136	505	16	413	4e-12	79.7
rs:WP_045688840	DNA topoisomerase I [Hymenobacter sp. AT01-02].	23.42	521	321	19	7	505	6	470	4e-12	79.7
rs:WP_041662546	DNA topoisomerase I [Streptomyces venezuelae].	24.11	560	315	22	7	505	15	525	4e-12	79.7
rs:WP_025673753	DNA topoisomerase I [Salinivibrio socompensis].	24.51	457	298	15	69	505	74	503	4e-12	79.7
tr:A0A0D6L2I0_9CYAN	SubName: Full=DNA topoisomerase TopA {ECO:0000313|EMBL:EKF05951.1};	24.26	507	299	14	95	566	49	505	4e-12	79.7
rs:WP_039150646	DNA topoisomerase I [Gallibacterium anatis].	23.81	441	284	16	88	505	93	504	4e-12	79.7
rs:WP_007524326	topoisomerase I [Haemophilus sputorum].	24.67	454	283	19	79	505	83	504	4e-12	79.7
rs:WP_012007264	DNA topoisomerase I [Prochlorococcus marinus].	25.15	509	304	18	101	579	85	546	4e-12	79.7
rs:WP_030483292	DNA topoisomerase I [Marmoricola aequoreus].	23.63	639	379	27	7	593	6	587	4e-12	79.7
rs:WP_046552789	DNA topoisomerase I [Arsukibacterium sp. MJ3].	24.43	438	286	14	88	505	83	495	4e-12	79.7
rs:WP_029795501	DNA topoisomerase I [Vibrio parahaemolyticus].	22.67	547	327	22	7	505	6	504	4e-12	79.7
tr:U5SEA8_9LACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AGY82458.1};	30.86	175	112	3	387	555	32	203	4e-12	78.2
rs:WP_042555596	DNA topoisomerase I [Pseudomonas fulva].	23.15	540	332	22	7	505	6	503	4e-12	79.7
tr:W4PQ42_9BACE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.84	339	188	13	7	336	6	293	4e-12	77.4
rs:WP_011789092	topoisomerase I [Shewanella sp. W3-18-1].	23.35	544	330	19	7	505	6	507	4e-12	79.7
rs:WP_029070660	DNA topoisomerase I [Kandleria vitulina].	23.80	521	325	17	7	505	5	475	4e-12	79.7
rs:WP_010702397	DNA topoisomerase I [Bartonella bovis].	25.44	456	264	22	97	504	65	492	4e-12	79.7
tr:A0A0A0NL09_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.76	564	313	23	7	505	16	527	4e-12	79.7
rs:WP_007648109	DNA topoisomerase I [Formosa sp. AK20].	24.66	519	309	18	7	504	6	463	4e-12	79.7
tr:A0A0A4HI73_9PSED	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.66	459	305	14	69	505	75	505	4e-12	79.7
rs:WP_025419976	DNA topoisomerase I [Borrelia anserina].	21.91	598	361	21	7	561	7	541	4e-12	79.7
rs:WP_025406842	DNA topoisomerase I [Borrelia hermsii].	23.70	595	354	24	7	561	7	541	4e-12	79.7
rs:WP_014016473	DNA topoisomerase I [Megasphaera elsdenii].	22.85	534	322	22	7	504	59	538	4e-12	79.7
rs:WP_031816604	DNA topoisomerase I [Vibrio parahaemolyticus].	23.83	449	293	17	79	505	6	427	4e-12	79.7
rs:WP_030323404	DNA topoisomerase I [Streptomyces flavochromogenes].	23.93	560	316	22	7	505	15	525	4e-12	79.7
rs:XP_005714936	DNA topoisomerase I Mitochondrial [Chondrus crispus].	25.45	613	343	28	7	567	37	587	4e-12	79.7
tr:C4XEP1_MYCFP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.95	440	298	12	85	504	60	478	4e-12	79.3
rs:WP_003705339	DNA topoisomerase I [Neisseria gonorrhoeae].	25.29	431	271	13	107	505	77	488	4e-12	79.7
rs:WP_025457058	DNA topoisomerase I [Neisseria polysaccharea].	24.16	534	319	19	7	505	6	488	4e-12	79.7
rs:WP_036728588	DNA topoisomerase I [Peptoniphilus sp. ChDC B134].	25.48	522	316	19	7	504	6	478	4e-12	79.3
rs:WP_015691241	DNA topoisomerase I [Saprospira grandis].	23.60	534	316	18	7	505	6	482	4e-12	79.7
rs:WP_033539235	DNA topoisomerase I [Shewanella sp. ECSMB14101].	25.30	419	268	16	107	505	114	507	4e-12	79.7
rs:WP_035857273	DNA topoisomerase I [Jeotgalicoccus marinus].	27.34	428	256	18	107	505	77	478	4e-12	79.3
rs:WP_045867561	DNA topoisomerase I [Tolypothrix sp. PCC 7601].	24.26	507	299	14	95	566	78	534	4e-12	79.7
rs:WP_020766839	DNA topoisomerase I [Leptospira santarosai].	24.76	529	314	20	1	505	1	469	4e-12	79.3
rs:WP_019818246	DNA topoisomerase I [Pseudomonas sp. CFT9].	22.83	460	303	15	69	505	75	505	4e-12	79.7
rs:WP_034284088	hypothetical protein [Aeromonas salmonicida].	24.34	226	154	5	4	222	1	216	4e-12	76.3
tr:J7BXN5_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.57	182	118	5	278	452	18	194	4e-12	75.9
rs:WP_021958984	DNA topoisomerase [Brachyspira sp. CAG:700].	24.74	574	330	24	7	553	22	520	4e-12	79.3
rs:WP_008730397	DNA topoisomerase I [Brachyspira hampsonii].	23.82	571	339	22	7	553	28	526	4e-12	79.3
rs:WP_021219539	topoisomerase I [Pseudomonas alcaligenes].	23.95	430	276	15	99	505	103	504	4e-12	79.7
rs:WP_029146385	DNA topoisomerase I [Microbacterium luticocti].	22.77	584	354	21	7	550	8	534	4e-12	79.7
rs:WP_006460213	DNA topoisomerase I [Thioalkalimicrobium aerophilum].	24.10	527	305	20	7	504	5	465	4e-12	79.7
rs:WP_033910715	DNA topoisomerase I [Neisseria gonorrhoeae].	25.29	431	271	13	107	505	77	488	4e-12	79.7
rs:WP_027467839	DNA topoisomerase I [Deefgea rivuli].	26.28	449	264	15	107	510	77	503	4e-12	79.7
rs:WP_039164285	DNA topoisomerase I [Gallibacterium anatis].	23.81	441	284	16	88	505	93	504	4e-12	79.7
tr:A0A0A8RQR3_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	482	289	19	80	505	65	523	4e-12	79.7
rs:WP_013161892	DNA topoisomerase I [Propionibacterium freudenreichii].	23.65	482	289	19	80	505	65	523	4e-12	79.7
rs:WP_036940538	DNA topoisomerase I [Propionibacterium freudenreichii].	23.65	482	289	19	80	505	65	523	4e-12	79.7
rs:WP_021921659	DNA topoisomerase [Acholeplasma sp. CAG:878].	23.08	520	324	18	7	504	5	470	4e-12	79.3
tr:A0A034TW46_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.59	540	337	20	7	505	6	505	4e-12	79.7
tr:F0LSG3_VIBFN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.53	459	300	15	69	505	17	446	4e-12	79.7
rs:WP_009218704	DNA topoisomerase I [Lachnospiraceae oral taxon 107].	24.77	436	279	14	97	504	67	481	4e-12	79.3
rs:WP_039631942	DNA topoisomerase I [Clostridium argentinense].	25.00	424	274	15	107	505	77	481	4e-12	79.3
tr:A0A090TAB4_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.41	457	301	17	69	504	67	495	4e-12	79.7
rs:WP_020385234	hypothetical protein [Kribbella catacumbae].	23.70	481	319	19	7	471	5	453	4e-12	79.7
rs:WP_028575888	DNA topoisomerase I [Desulfonatronovibrio hydrogenovorans].	23.97	438	290	14	91	505	61	478	4e-12	79.3
rs:WP_018520405	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.08	559	324	22	7	505	15	527	4e-12	79.7
rs:WP_035135932	DNA topoisomerase I [Flavobacterium beibuense].	25.10	526	298	23	7	504	6	463	4e-12	79.7
rs:WP_012953898	DNA topoisomerase I [Candidatus Atelocyanobacterium thalassa].	23.52	455	290	14	89	504	72	507	4e-12	79.7
rs:WP_034471440	DNA topoisomerase I [Afipia sp. P52-10].	22.86	538	333	20	4	505	1	492	4e-12	79.7
rs:WP_014994167	topoisomerase I [Alcanivorax dieselolei].	22.49	458	311	13	69	505	79	513	4e-12	79.7
rs:XP_008650522	PREDICTED: uncharacterized protein LOC103631377 [Zea mays].	27.11	380	229	13	36	390	316	672	4e-12	79.7
rs:WP_004697212	DNA topoisomerase I [Veillonella parvula].	24.38	525	318	22	7	504	76	548	4e-12	79.3
tr:A0A0A8PWE8_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	482	289	19	80	505	65	523	4e-12	79.7
gpu:CP009505_1133	DNA topoisomerase I [Methanosarcina sp. MTP4]	24.86	519	326	19	8	498	6	488	5e-12	79.7
tr:G0EL64_BRAIP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.77	568	337	22	10	553	2	497	5e-12	79.3
rs:WP_009416627	DNA topoisomerase I [Capnocytophaga sp. oral taxon 332].	23.42	521	313	20	7	504	6	463	5e-12	79.7
rs:WP_015130898	DNA topoisomerase I [Calothrix sp. PCC 7507].	24.95	521	284	18	95	566	78	540	5e-12	79.7
rs:WP_007101752	DNA topoisomerase I [Synechococcus sp. RS9917].	25.60	457	262	18	97	505	81	507	5e-12	79.7
tr:C4K2S3_RICPU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.71	544	329	21	7	510	4	501	5e-12	79.3
rs:WP_020984932	DNA topoisomerase I [Leptospira alexanderi].	22.77	527	325	18	1	504	1	468	5e-12	79.3
rs:WP_022498137	DNA topoisomerase [Megasphaera elsdenii CAG:570].	22.85	534	322	22	7	504	59	538	5e-12	79.3
rs:WP_035181783	DNA topoisomerase I [Bacillus coagulans].	25.42	421	264	15	112	504	82	480	5e-12	79.3
rs:WP_010764920	DNA topoisomerase 1 [Enterococcus moraviensis].	23.68	532	327	18	1	504	1	481	5e-12	79.3
rs:WP_036857940	DNA topoisomerase I, partial [Prevotella amnii].	27.62	210	129	5	5	206	3	197	5e-12	75.9
rs:WP_016415618	topoisomerase I [Halomonas anticariensis].	23.22	478	307	17	46	505	75	510	5e-12	79.7
rs:WP_013526780	DNA topoisomerase I [Mycoplasma fermentans].	23.04	434	293	12	91	504	63	475	5e-12	79.3
tr:A9M455_NEIM0	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.29	431	271	13	107	505	57	468	5e-12	79.3
rs:WP_012388160	DNA topoisomerase I [Leptospira biflexa].	23.94	472	286	21	76	505	14	454	5e-12	79.3
rs:WP_013354513	DNA topoisomerase I [Mycoplasma fermentans].	22.95	440	298	12	85	504	57	475	5e-12	79.3
rs:WP_029573099	DNA topoisomerase I, partial [Pseudomonas syringae].	23.48	460	300	15	69	505	75	505	5e-12	79.0
rs:WP_004520185	DNA topoisomerase I [Neisseria subflava].	24.72	534	316	21	7	505	6	488	5e-12	79.3
rs:WP_028621958	DNA topoisomerase I [Pseudomonas sp. Ant30-3].	22.37	456	310	13	69	505	75	505	5e-12	79.7
tr:S7TBH8_9DELT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.32	536	322	18	7	505	13	496	5e-12	79.3
rs:WP_038442188	DNA topoisomerase I [Pseudomonas fluorescens].	23.42	427	282	14	99	505	104	505	5e-12	79.7
rs:WP_031854645	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	23.97	438	286	16	88	505	1	411	5e-12	79.3
rs:WP_009628373	DNA topoisomerase I [Pseudanabaena biceps].	24.28	453	282	15	91	505	67	496	5e-12	79.3
rs:WP_024777914	DNA topoisomerase I [Pseudomonas corrugata].	22.44	459	306	14	69	505	75	505	5e-12	79.7
rs:WP_037017484	DNA topoisomerase I [Rhizobiales bacterium YIM 77505].	22.95	549	334	19	4	510	1	502	5e-12	79.7
rs:WP_041594206	DNA topoisomerase I [Mycoplasma fermentans].	23.04	434	293	12	91	504	63	475	5e-12	79.3
rs:WP_044163613	DNA topoisomerase I [Bacteroides reticulotermitis].	24.34	534	298	20	7	504	6	469	5e-12	79.3
rs:WP_020490544	hypothetical protein [Dehalobacter sp. FTH1].	23.26	559	331	19	7	505	9	529	5e-12	79.7
rs:WP_015317636	DNA topoisomerase I [Mesorhizobium australicum].	24.86	547	311	24	4	505	1	492	5e-12	79.3
rs:WP_045275221	DNA topoisomerase I [Microbacterium ketosireducens].	23.25	542	336	19	7	505	8	512	5e-12	79.7
rs:WP_024590097	MULTISPECIES: DNA topoisomerase I [Pseudoalteromonas].	22.37	456	310	14	69	505	77	507	5e-12	79.7
rs:WP_013301081	DNA topoisomerase I [Parvularcula bermudensis].	23.11	541	324	21	4	505	1	488	5e-12	79.3
rs:WP_026098772	DNA topoisomerase I [Oscillatoria sp. PCC 10802].	23.64	605	348	21	5	566	3	536	5e-12	79.7
rs:WP_007709436	DNA topoisomerase I, partial [Sphingobium sp. AP49].	26.53	392	230	14	7	389	4	346	5e-12	78.2
rs:WP_035676396	DNA topoisomerase I [Azospirillum brasilense].	24.68	547	317	22	1	505	1	494	5e-12	79.7
rs:WP_023007343	topoisomerase I [Halomonas sp. PBN3].	24.15	439	285	15	88	505	99	510	5e-12	79.3
rs:WP_047012081	DNA topoisomerase I [Spongiibacter sp. IMCC21906].	22.58	434	298	13	88	505	100	511	5e-12	79.3
rs:XP_656880	DNA topoisomerase III [Entamoeba histolytica HM-1:IMSS].	23.40	453	303	13	91	532	96	515	5e-12	79.0
tr:A0A0A8TBV7_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	482	289	19	80	505	65	523	5e-12	79.7
rs:WP_042232965	DNA topoisomerase I [Paenibacillus chitinolyticus].	24.33	526	320	21	7	504	6	481	5e-12	79.3
rs:WP_025248461	DNA topoisomerase I [Pasteurella multocida].	22.24	553	330	18	3	505	2	504	5e-12	79.3
rs:WP_036846570	DNA topoisomerase I, partial [Porphyromonas sp. COT-108 OH1349].	27.83	230	144	5	4	225	1	216	5e-12	75.9
rs:WP_012271345	topoisomerase I [Pseudomonas putida].	23.02	530	346	17	7	505	6	504	5e-12	79.3
rs:WP_004307878	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.10	526	304	20	7	504	6	469	5e-12	79.3
rs:WP_021785427	MULTISPECIES: topoisomerase I [Pseudomonas putida group].	23.02	530	346	17	7	505	6	504	5e-12	79.3
rs:WP_036258305	DNA topoisomerase I [Methylocapsa aurea].	25.23	543	313	23	4	505	1	491	5e-12	79.7
rs:WP_046690637	DNA topoisomerase I [Leptospira santarosai].	23.90	523	316	19	7	505	5	469	5e-12	79.0
rs:XP_008466289	PREDICTED: uncharacterized protein LOC103503742 [Cucumis melo].	25.90	471	265	17	107	518	77	522	5e-12	79.3
rs:WP_018514247	DNA topoisomerase I [Streptomyces sp. ScaeMP-e10].	23.08	559	324	21	7	505	15	527	5e-12	79.7
rs:WP_044636391	DNA topoisomerase I [Propionibacterium freudenreichii].	23.65	482	289	19	80	505	65	523	5e-12	79.3
rs:WP_042747138	hypothetical protein [Staphylococcus aureus].	24.65	430	239	18	38	407	46	450	5e-12	79.0
rs:WP_019648305	topoisomerase I [Pseudomonas sp. 45MFCol3.1].	21.93	456	312	13	69	505	75	505	5e-12	79.3
rs:WP_022115579	DNA topoisomerase [Clostridium sp. CAG:524].	24.31	543	313	25	7	512	5	486	5e-12	79.3
rs:WP_027500390	DNA topoisomerase I [Rhodococcus sp. UNC363MFTsu5.1].	24.83	588	343	22	7	550	23	555	5e-12	79.3
rs:WP_010262215	DNA topoisomerase I [Alistipes timonensis].	23.47	524	313	18	7	504	6	467	5e-12	79.3
rs:WP_046720801	DNA topoisomerase I [Bacillus coagulans].	25.42	421	264	15	112	504	82	480	5e-12	79.3
rs:WP_003700733	DNA topoisomerase I [Neisseria gonorrhoeae].	25.40	433	268	15	107	505	77	488	5e-12	79.3
rs:WP_041421399	DNA topoisomerase I [Neisseria gonorrhoeae].	25.29	431	271	13	107	505	77	488	5e-12	79.3
tr:B4RPY3_NEIG2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.40	433	268	15	107	505	93	504	5e-12	79.3
rs:WP_016714898	topoisomerase I [Pseudomonas monteilii].	23.02	530	346	17	7	505	6	504	5e-12	79.3
rs:WP_003248770	DNA topoisomerase I [Pseudomonas putida].	23.02	530	346	17	7	505	6	504	5e-12	79.3
tr:A0A073I4G1_9PORP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.31	547	324	21	7	525	43	527	5e-12	79.3
rs:WP_025803824	DNA topoisomerase I [Campylobacter sp. CIT045].	22.91	563	345	17	5	548	4	496	5e-12	79.0
rs:WP_026487707	DNA topoisomerase I [Butyrivibrio sp. XBB1001].	25.55	454	262	23	93	504	57	476	5e-12	79.3
rs:WP_038414203	DNA topoisomerase I [Pseudomonas cremoricolorata].	23.13	454	309	13	69	505	74	504	5e-12	79.3
rs:WP_009404616	DNA topoisomerase I subunit omega [Pseudomonas putida].	22.83	530	347	17	7	505	6	504	5e-12	79.3
rs:WP_033310216	DNA topoisomerase I [Streptomyces iakyrus].	23.66	558	320	24	7	505	15	525	5e-12	79.3
tr:U7UTY2_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.52	540	311	19	7	504	12	491	5e-12	79.3
rs:XP_007605148	hypothetical protein VICG_01703 [Vittaforma corneae ATCC 50505].	23.50	566	354	21	8	543	6	522	5e-12	79.3
rs:WP_028941161	DNA topoisomerase I [Pseudomonas umsongensis].	21.93	456	312	13	69	505	75	505	5e-12	79.3
rs:WP_027335956	DNA topoisomerase I [Halomonas sp. HL-48].	24.29	457	299	16	69	505	80	509	5e-12	79.3
rs:WP_002351500	DNA topoisomerase, partial [Enterococcus faecium].	31.61	174	110	5	379	544	25	197	5e-12	76.6
rs:WP_036889264	hypothetical protein, partial [Prevotella aurantiaca].	25.86	232	147	6	331	550	1	219	5e-12	77.8
tr:I6H4J9_SHIFL	SubName: Full=DNA topoisomerase 3 domain protein {ECO:0000313|EMBL:EIQ75691.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EIQ75691.1}; Flags: Fragment;	27.98	218	145	5	97	305	11	225	5e-12	75.9
rs:WP_039257944	DNA topoisomerase I [Clostridium botulinum].	23.62	542	333	21	7	517	6	497	5e-12	79.3
rs:WP_041173544	DNA topoisomerase I [Clostridium botulinum].	24.91	550	318	23	7	517	6	499	5e-12	79.3
rs:WP_014679529	DNA topoisomerase I [Solitalea canadensis].	24.51	457	278	15	80	505	48	468	5e-12	79.3
rs:WP_003694350	DNA topoisomerase I [Neisseria gonorrhoeae].	24.58	533	318	20	7	505	6	488	5e-12	79.3
tr:B1KWM7_CLOBM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.91	550	318	23	7	517	10	503	5e-12	79.3
rs:WP_025375806	DNA topoisomerase I [Borrelia parkeri].	22.89	603	349	24	7	561	7	541	5e-12	79.3
rs:WP_038647025	DNA topoisomerase I [Mesorhizobium huakuii].	25.05	547	310	25	4	505	1	492	5e-12	79.3
rs:WP_017554457	DNA topoisomerase I [Bacillus coagulans].	25.89	421	262	15	112	504	82	480	6e-12	79.0
rs:WP_014591780	topoisomerase I [Pseudomonas putida].	23.02	530	346	17	7	505	6	504	6e-12	79.3
tr:Q2PY64_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.98	517	316	18	7	504	6	464	6e-12	79.3
rs:WP_009016940	DNA topoisomerase I [Parabacteroides sp. D13].	24.31	547	324	21	7	525	6	490	6e-12	79.3
rs:WP_021802116	DNA topoisomerase I [Clostridium intestinale].	24.43	528	316	20	7	505	6	479	6e-12	79.0
rs:WP_009533718	DNA topoisomerase I [Stomatobaculum longum].	23.56	450	278	19	93	504	63	484	6e-12	79.0
rs:WP_018925317	MULTISPECIES: topoisomerase I [Pseudomonas].	21.93	456	312	13	69	505	75	505	6e-12	79.3
rs:WP_023810547	DNA topoisomerase I [Mesorhizobium sp. L2C084A000].	23.88	536	330	20	4	505	1	492	6e-12	79.3
rs:WP_025858485	DNA topoisomerase I [Pseudomonas sp. CHM02].	22.70	533	345	18	7	505	6	505	6e-12	79.3
rs:WP_029454711	DNA topoisomerase I [Candidatus Pelagibacter ubique].	24.39	533	319	22	7	505	4	486	6e-12	79.3
rs:WP_029478369	DNA topoisomerase I [Deinococcus frigens].	24.73	558	321	23	3	505	2	515	6e-12	79.3
rs:WP_040922148	DNA topoisomerase I [Saccharomonospora xinjiangensis].	23.27	550	338	19	7	505	21	537	6e-12	79.3
rs:WP_017249339	DNA topoisomerase I [Brevibacillus brevis].	23.62	525	328	19	5	504	4	480	6e-12	79.0
rs:WP_046189722	DNA topoisomerase I [Mycobacterium arupense].	23.27	550	334	21	7	504	21	534	6e-12	79.3
rs:WP_043411915	DNA topoisomerase III, partial [Streptomyces pluripotens].	29.39	228	132	9	353	568	18	228	6e-12	75.9
tr:V7PWA5_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.85	582	340	23	7	557	4	507	6e-12	79.3
rs:WP_043534481	DNA topoisomerase I [Actinomyces sp. MS2].	23.04	573	324	21	1	505	1	524	6e-12	79.3
rs:WP_029910794	DNA topoisomerase I [Hydrogenovibrio marinus].	23.29	511	328	16	7	504	5	464	6e-12	79.3
rs:WP_031851619	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	6e-12	79.3
rs:WP_009209696	DNA topoisomerase I [Aurantimonas manganoxydans].	24.24	557	308	24	4	505	1	498	6e-12	79.3
rs:WP_031572738	DNA topoisomerase I [Proteiniclasticum ruminis].	27.09	443	259	20	97	505	67	479	6e-12	79.0
tr:K6AC25_9PORP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.31	547	324	21	7	525	30	514	6e-12	79.3
rs:WP_022421259	DNA topoisomerase [Clostridium sp. CAG:307].	24.88	426	275	13	99	505	70	469	6e-12	79.0
rs:WP_022226467	DNA topoisomerase [Clostridium sp. CAG:302].	25.52	435	270	19	97	506	70	475	6e-12	79.0
rs:WP_010629088	topoisomerase I [Halomonas sp. KM-1].	23.85	436	289	15	88	505	99	509	6e-12	79.3
rs:WP_005644977	topoisomerase I [Haemophilus haemolyticus].	23.86	549	326	23	3	505	2	504	6e-12	79.3
rs:WP_014127330	DNA topoisomerase [Thermoproteus tenax].	21.43	560	379	20	7	548	3	519	6e-12	79.0
rs:WP_043253486	DNA topoisomerase I [Pseudomonas knackmussii].	24.25	433	271	16	99	505	103	504	6e-12	79.3
rs:WP_020539370	hypothetical protein [Lewinella cohaerens].	24.10	527	309	22	7	504	6	470	6e-12	79.3
rs:WP_011363601	DNA topoisomerase I [Synechococcus sp. CC9605].	23.90	611	361	20	5	579	4	546	6e-12	79.3
rs:WP_019858383	DNA topoisomerase I [Mesorhizobium loti].	24.44	540	322	22	4	505	1	492	6e-12	79.3
rs:WP_010909698	DNA topoisomerase I [Mesorhizobium loti].	24.44	540	322	22	4	505	1	492	6e-12	79.3
rs:WP_033296544	DNA topoisomerase I [Streptomyces atroolivaceus].	23.43	559	322	22	7	505	13	525	6e-12	79.3
tr:R8VV53_9CLOT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.77	537	314	21	7	505	5	489	6e-12	79.3
rs:WP_005867659	DNA topoisomerase I [Parabacteroides sp. CAG:2].	24.31	547	324	21	7	525	30	514	6e-12	79.3
rs:WP_015140585	DNA topoisomerase I [Nostoc sp. PCC 7524].	24.26	507	299	16	95	566	78	534	6e-12	79.3
rs:WP_018355602	topoisomerase I [Pasteurella pneumotropica].	22.91	537	346	18	3	505	2	504	6e-12	79.3
tr:W4RHE9_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.07	229	146	7	135	357	5	218	6e-12	75.9
rs:WP_010691949	DNA topoisomerase I [Fructobacillus fructosus].	24.12	481	311	21	7	459	6	460	6e-12	79.0
rs:WP_019418404	DNA topoisomerase I [Anoxybacillus kamchatkensis].	24.05	528	310	22	112	598	82	559	6e-12	79.0
gpu:CP009518_1400	DNA topoisomerase I [Methanococcoides methylutens MM1]	24.32	518	325	19	48	548	5	472	6e-12	79.0
rs:WP_010753926	DNA topoisomerase 1 [Enterococcus asini].	24.09	523	324	18	7	504	7	481	6e-12	79.0
rs:WP_017488557	DNA topoisomerase I [Micrococcus luteus].	23.54	565	324	21	7	505	19	541	6e-12	79.3
rs:WP_044499834	DNA topoisomerase I [Pseudomonas sp. 12M76_air].	23.08	455	297	15	99	540	100	514	6e-12	79.3
rs:WP_027097528	DNA topoisomerase I [Clostridium paraputrificum].	26.03	534	300	26	7	505	6	479	6e-12	79.0
rs:WP_003189652	MULTISPECIES: topoisomerase I [Pseudomonas].	22.44	459	306	14	69	505	75	505	6e-12	79.3
rs:WP_028693758	DNA topoisomerase I [Pseudomonas cremoricolorata].	23.35	454	308	13	69	505	74	504	6e-12	79.3
tr:Q2SD25_HAHCH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.55	541	339	19	7	505	19	521	6e-12	79.3
rs:WP_005603755	DNA topoisomerase I [Butyrivibrio crossotus].	25.06	443	276	16	93	504	63	480	6e-12	79.0
rs:WP_012157752	DNA topoisomerase I [Frankia sp. EAN1pec].	23.06	568	332	20	7	510	79	605	6e-12	79.3
rs:WP_010691753	DNA topoisomerase I [Fructobacillus fructosus].	24.05	524	322	19	7	505	29	501	6e-12	79.0
rs:WP_034126645	DNA topoisomerase I [Pseudomonas fluorescens].	22.44	459	306	14	69	505	75	505	6e-12	79.3
rs:WP_028452852	DNA topoisomerase I [Chitinilyticum aquatile].	26.83	451	257	18	107	510	77	501	6e-12	79.0
rs:WP_038627467	DNA topoisomerase I [Corynebacterium sp. ATCC 6931].	25.22	460	275	18	97	505	86	527	6e-12	79.3
rs:WP_039125636	DNA topoisomerase I [Francisella guangzhouensis].	23.59	619	359	22	7	581	6	554	6e-12	79.0
rs:WP_041598850	DNA topoisomerase I [Hahella chejuensis].	22.55	541	339	19	7	505	6	508	6e-12	79.3
rs:WP_025738670	DNA topoisomerase I [Salinivibrio socompensis].	24.51	457	298	15	69	505	74	503	6e-12	79.3
rs:WP_044015757	DNA topoisomerase I [Treponema sp. OMZ 838].	23.19	526	323	21	7	504	1	473	6e-12	79.0
rs:WP_012056085	DNA topoisomerase I [Parabacteroides distasonis].	24.31	547	324	21	7	525	6	490	6e-12	79.0
rs:WP_006927518	DNA topoisomerase I [Caldithrix abyssi].	21.75	639	394	23	7	607	10	580	6e-12	79.0
rs:WP_003679500	DNA topoisomerase I [Neisseria flavescens].	24.48	531	321	18	7	505	6	488	6e-12	79.0
rs:WP_005811721	DNA topoisomerase I [Bacteroides fragilis].	23.70	595	353	24	7	564	6	536	6e-12	79.0
rs:WP_018428142	DNA topoisomerase I [Hoeflea sp. 108].	23.30	545	322	21	4	505	1	492	6e-12	79.3
rs:WP_040257479	DNA topoisomerase I [Rickettsia hoogstraalii].	25.05	455	284	17	96	510	64	501	6e-12	79.0
rs:WP_010193401	DNA topoisomerase I [Bacillus sp. m3-13].	25.30	423	263	15	112	504	82	481	6e-12	79.0
rs:WP_029076598	DNA topoisomerase I [Kaistia adipata].	25.93	482	281	23	80	510	46	502	6e-12	79.3
rs:WP_046037550	DNA topoisomerase I [Campylobacter fetus].	25.00	460	281	18	73	505	48	470	6e-12	79.0
rs:WP_015357483	DNA topoisomerase I TopA [Mycobacterium liflandii].	24.52	469	287	17	86	505	88	538	6e-12	79.3
rs:WP_036617743	DNA topoisomerase I [Parabacteroides distasonis].	24.31	547	324	21	7	525	6	490	6e-12	79.0
rs:WP_008174370	MULTISPECIES: topoisomerase I [Marinobacter].	20.96	544	346	17	7	505	6	510	6e-12	79.3
rs:WP_030209244	DNA topoisomerase I [Streptomyces griseoluteus].	24.11	560	315	22	7	505	15	525	6e-12	79.3
gp:FR773526_2425	DNA topoisomerase I [Clostridium botulinum H04402 065]	25.14	549	318	24	7	517	10	503	6e-12	79.0
rs:WP_035727327	DNA topoisomerase I [Flexibacter elegans].	24.59	431	257	14	7	430	6	375	6e-12	79.0
rs:WP_032536933	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.70	595	353	24	7	564	6	536	6e-12	79.0
rs:WP_008777893	MULTISPECIES: DNA topoisomerase I [Parabacteroides].	24.31	547	324	21	7	525	6	490	6e-12	79.0
rs:WP_008772731	MULTISPECIES: DNA topoisomerase I [Bacteroidales].	24.31	547	324	21	7	525	6	490	6e-12	79.0
rs:WP_034102544	DNA topoisomerase I [Pseudomonas fluorescens].	22.44	459	306	14	69	505	75	505	6e-12	79.0
tr:A6QKL4_ONYPH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.77	508	304	21	19	504	3	464	6e-12	79.0
rs:WP_003609775	DNA topoisomerase I [Methylosinus trichosporium].	24.47	515	305	24	34	505	18	491	6e-12	79.3
rs:WP_006190095	DNA topoisomerase I [Treponema vincentii].	23.38	526	322	21	7	504	19	491	6e-12	79.0
rs:WP_042348935	DNA topoisomerase I [Bacillus sp. G2(2012b)].	25.12	422	264	13	112	504	82	480	6e-12	79.0
tr:A0A060PQD6_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	29.30	215	128	7	308	505	14	221	6e-12	78.2
rs:WP_046026992	DNA topoisomerase I [Pseudomonas fluorescens].	21.93	456	312	13	69	505	75	505	6e-12	79.0
rs:WP_031588933	DNA topoisomerase I [Kandleria vitulina].	23.80	521	325	17	7	505	5	475	6e-12	79.0
rs:WP_029321743	DNA topoisomerase I [Butyrivibrio sp. AE3004].	24.20	533	314	26	7	505	9	485	7e-12	79.0
tr:V8CP57_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETD29168.1};	31.36	169	101	4	375	531	1	166	7e-12	77.0
sp:TOP1_PYRFU	RecName: Full=DNA topoisomerase 1; EC=5.99.1.2; AltName: Full=DNA topoisomerase I; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme; Contains: RecName: Full=Endonuclease PI-PfuI; EC=3.1.-.-; AltName: Full=Pfu topA intein;	25.00	332	208	12	7	322	4	310	7e-12	79.3
sp:TOP1_PYRFU	RecName: Full=DNA topoisomerase 1; EC=5.99.1.2; AltName: Full=DNA topoisomerase I; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme; Contains: RecName: Full=Endonuclease PI-PfuI; EC=3.1.-.-; AltName: Full=Pfu topA intein;	27.35	234	121	10	330	546	689	890	3e-08	67.4
rs:WP_002547495	DNA topoisomerase I [Propionibacterium acnes].	24.17	480	284	19	80	505	64	517	7e-12	79.0
rs:WP_022822824	DNA topoisomerase I [Hymenobacter norwichensis].	23.02	530	316	20	7	505	6	474	7e-12	79.0
rs:WP_002540185	DNA topoisomerase I [Grimontia indica].	22.81	456	307	14	69	505	74	503	7e-12	79.0
rs:WP_040267900	DNA topoisomerase I [Xanthomonas citri].	24.18	488	316	20	43	505	25	483	7e-12	79.0
rs:WP_041926692	DNA topoisomerase I [Clostridium botulinum].	25.14	549	318	24	7	517	6	499	7e-12	79.0
tr:A0A094Q164_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KGA15784.1};	23.37	552	326	22	7	505	9	516	7e-12	79.0
rs:WP_026509973	DNA topoisomerase I [Butyrivibrio sp. LC3010].	24.32	444	281	19	93	505	66	485	7e-12	79.0
rs:WP_030139950	DNA topoisomerase I [Pseudomonas fluorescens].	22.44	459	306	14	69	505	75	505	7e-12	79.0
rs:XP_008859836	DNA topoisomerase domain containing protein [Entamoeba nuttalli P19].	23.40	453	303	13	91	532	96	515	7e-12	78.6
rs:WP_036458469	DNA topoisomerase I, partial [Mycoplasma iners].	23.05	538	305	23	7	504	5	473	7e-12	78.6
rs:WP_046847126	DNA topoisomerase I [Hyphomicrobium sp. GJ21].	25.35	493	267	18	80	505	46	504	7e-12	79.0
rs:WP_022503383	DNA topoisomerase [Mycoplasma sp. CAG:776].	24.60	622	370	24	7	603	5	552	7e-12	79.0
tr:F2IVZ0_POLGS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.43	454	265	21	107	510	70	504	7e-12	79.0
rs:WP_017254452	topoisomerase I [Pseudomonas tolaasii].	22.44	459	306	14	69	505	75	505	7e-12	79.0
rs:WP_036060875	DNA topoisomerase I [Leuconostoc citreum].	24.39	529	312	22	7	504	25	496	7e-12	79.0
rs:WP_007933178	topoisomerase I [Pseudomonas sp. GM18].	21.93	456	312	13	69	505	75	505	7e-12	79.0
rs:WP_005865502	DNA topoisomerase I [Bartonella alsatica].	25.49	455	265	20	97	504	65	492	7e-12	79.0
rs:WP_010981336	TraB protein [uncultured bacterium].	23.74	497	302	16	88	555	65	513	7e-12	79.0
rs:WP_021809457	DNA topoisomerase I [Leifsonia rubra].	25.21	583	330	26	7	540	8	533	7e-12	79.0
rs:WP_020603436	DNA topoisomerase I [Spirosoma spitsbergense].	24.65	434	258	15	7	431	6	379	7e-12	79.0
rs:WP_002529102	DNA topoisomerase I [Propionibacterium humerusii].	23.84	474	279	19	86	505	72	517	7e-12	79.0
rs:WP_032853999	DNA topoisomerase I [Pasteurella multocida].	24.61	447	273	16	88	505	93	504	7e-12	79.0
rs:WP_009674480	MULTISPECIES: DNA topoisomerase I [Paenibacillus].	24.33	526	320	21	7	504	6	481	7e-12	79.0
rs:WP_010135732	DNA topoisomerase I [Flavobacteriaceae bacterium S85].	24.62	520	308	19	7	504	6	463	7e-12	79.0
rs:WP_039142357	DNA topoisomerase I [Gallibacterium anatis].	23.81	441	284	16	88	505	93	504	7e-12	79.0
rs:WP_043198376	DNA topoisomerase I [Pseudomonas putida].	23.02	530	346	17	7	505	6	504	7e-12	79.0
rs:WP_020192583	topoisomerase I, partial [Pseudomonas putida].	23.02	530	346	17	7	505	6	504	7e-12	79.0
rs:WP_029635562	DNA topoisomerase I [actinobacterium SCGC AAA041-L13].	23.58	564	331	23	4	510	9	529	7e-12	79.0
rs:WP_009625014	DNA topoisomerase I [Pseudanabaena biceps].	23.89	452	285	15	91	505	67	496	7e-12	79.0
rs:WP_004916145	DNA topoisomerase I [Riemerella anatipestifer].	23.91	527	304	24	7	504	6	464	7e-12	79.0
rs:WP_025613452	DNA topoisomerase I [Vibrio parahaemolyticus].	22.79	544	330	21	7	505	6	504	7e-12	79.0
rs:WP_041364416	DNA topoisomerase I [Mycoplasma pulmonis].	23.84	537	295	22	7	504	5	466	7e-12	78.6
rs:WP_004248126	topoisomerase I [Proteus mirabilis].	22.35	537	335	19	7	505	6	498	7e-12	79.0
rs:WP_005696133	topoisomerase I [Haemophilus parainfluenzae].	23.33	553	324	22	3	505	2	504	7e-12	79.0
rs:WP_037690948	DNA topoisomerase I [Streptomyces atratus].	23.08	559	324	23	7	505	15	527	7e-12	79.0
rs:WP_046294178	DNA topoisomerase I [Mycobacterium sp. UM_Kg17].	24.15	468	288	16	86	504	85	534	7e-12	79.0
rs:WP_018958827	DNA topoisomerase I [Streptomyces sp. CNB091].	22.90	559	325	21	7	505	15	527	7e-12	79.0
rs:WP_031331786	DNA topoisomerase I [Williamsia sp. D3].	23.69	553	328	21	7	505	19	531	7e-12	79.0
tr:V8D3C4_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.69	553	328	21	7	505	24	536	7e-12	79.0
tr:A0A0B8Q1Z1_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM73505.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAM73505.1};	31.97	147	95	2	405	548	1	145	7e-12	75.9
rs:WP_015547003	DNA topoisomerase I [Alistipes shahii].	23.76	526	309	19	7	504	6	467	7e-12	79.0
rs:WP_005838811	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.28	524	316	22	7	504	6	469	7e-12	79.0
rs:WP_010555034	topoisomerase I [Pseudoalteromonas arctica].	22.03	454	314	13	69	505	77	507	7e-12	79.0
rs:WP_041375469	DNA topoisomerase I [Polymorphum gilvum].	26.43	454	265	21	107	510	75	509	7e-12	79.0
rs:WP_003697687	DNA topoisomerase I [Neisseria gonorrhoeae].	23.87	532	323	17	7	505	6	488	7e-12	79.0
rs:WP_015462660	MULTISPECIES: DNA topoisomerase I [Xanthomonas].	24.18	488	316	20	43	505	25	483	7e-12	79.0
rs:WP_045529134	DNA topoisomerase I [Clavibacter michiganensis].	22.50	551	335	18	7	505	8	518	7e-12	79.0
rs:WP_008668551	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.28	524	316	22	7	504	6	469	7e-12	79.0
tr:F2BVU5_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	23.37	475	297	16	7	464	46	470	8e-12	78.2
rs:WP_012305122	DNA topoisomerase I [Leuconostoc citreum].	24.39	529	312	22	7	504	28	499	8e-12	78.6
rs:XP_006572532	PREDICTED: DNA topoisomerase 3-like, partial [Apis mellifera].	25.76	330	210	10	198	504	30	347	8e-12	78.2
rs:WP_003999165	DNA topoisomerase [Streptomyces viridochromogenes].	23.84	558	319	24	7	505	15	525	8e-12	79.0
tr:C0FQD4_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.93	443	282	18	93	504	63	481	8e-12	79.0
rs:WP_011114836	type 1 DNA topoisomerase [Rhodococcus equi].	25.06	451	266	20	7	425	3	413	8e-12	79.0
rs:WP_031308079	MULTISPECIES: hypothetical protein, partial [Bacillus].	24.93	341	224	11	97	424	4	325	8e-12	78.6
rs:WP_046786461	DNA topoisomerase I [Pseudomonas putida].	22.77	527	351	16	7	505	6	504	8e-12	79.0
rs:WP_010080299	DNA topoisomerase I [Micrococcus luteus].	23.45	563	327	22	7	505	19	541	8e-12	79.0
rs:WP_021112282	DNA topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	8e-12	79.0
rs:WP_018066740	DNA topoisomerase I [Martelella mediterranea].	24.41	553	325	24	4	510	1	506	8e-12	79.0
rs:WP_011032137	DNA topoisomerase [Methanosarcina mazei].	23.84	516	335	19	8	498	6	488	8e-12	79.0
rs:WP_046735689	DNA topoisomerase I [Xanthomonas axonopodis].	24.65	434	278	17	97	505	74	483	8e-12	79.0
rs:WP_044919789	DNA topoisomerase I [Lachnospiraceae bacterium MA2020].	24.44	532	318	23	7	505	6	486	8e-12	78.6
rs:WP_031410440	DNA topoisomerase I [Geobacillus vulcani].	22.67	622	383	21	7	598	6	559	8e-12	78.6
gpu:CP011268_787	DNA topoisomerase 1 [candidate division SR1 bacterium Aalborg_AAW-1]	25.58	434	249	17	7	430	33	402	8e-12	79.0
rs:WP_031560908	DNA topoisomerase I, partial [Acinetobacter baumannii].	26.07	326	200	11	201	505	26	331	8e-12	78.6
rs:WP_011009064	DNA topoisomerase [Pyrobaculum aerophilum].	21.36	590	378	22	7	567	4	536	8e-12	78.6
rs:WP_012720956	DNA topoisomerase I [Clostridium botulinum].	24.36	546	326	20	7	517	6	499	8e-12	78.6
rs:WP_039601790	DNA topoisomerase I [Pseudomonas putida].	22.77	527	351	16	7	505	6	504	8e-12	79.0
rs:WP_045052677	DNA topoisomerase I [Chroococcales cyanobacterium CENA595].	23.72	527	317	16	89	581	72	547	8e-12	79.0
rs:WP_025068382	DNA topoisomerase, partial [Prevotella denticola].	31.48	162	102	4	376	531	26	184	8e-12	77.0
rs:WP_028442111	DNA topoisomerase I [Streptomyces sp. DpondAA-B6].	22.90	559	325	22	7	505	15	527	8e-12	79.0
rs:WP_037877861	DNA topoisomerase I [Streptomyces sp. NTK 937].	22.90	559	325	22	7	505	15	527	8e-12	79.0
tr:A0A077MCJ1_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.88	555	341	23	1	504	1	519	8e-12	79.0
tr:F3P1P8_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.84	474	279	19	86	505	55	500	8e-12	79.0
rs:WP_041129894	DNA topoisomerase I [Streptomyces vietnamensis].	23.52	557	322	23	7	505	15	525	8e-12	79.0
rs:WP_002178555	DNA topoisomerase I [Leptospira interrogans].	24.76	525	311	20	5	504	3	468	8e-12	78.6
rs:WP_006511007	DNA topoisomerase I [Xenococcus sp. PCC 7305].	24.56	456	278	16	91	504	74	505	8e-12	79.0
rs:WP_035916355	DNA topoisomerase I [Knoellia sinensis].	22.16	546	342	18	7	505	6	515	8e-12	79.0
rs:WP_015269531	MULTISPECIES: DNA topoisomerase I subunit omega [Pseudomonas].	23.02	530	346	17	7	505	6	504	8e-12	79.0
rs:WP_043452743	DNA topoisomerase I [Granulibacter bethesdensis].	23.99	542	316	25	7	505	5	493	8e-12	79.0
rs:XP_004039715	hypothetical protein IMG5_012580, partial [Ichthyophthirius multifiliis].	21.97	578	382	18	7	553	58	597	8e-12	78.6
rs:WP_003234049	DNA topoisomerase I subunit omega [Pseudomonas fluorescens].	22.88	459	304	15	69	505	75	505	8e-12	79.0
rs:WP_030015206	DNA topoisomerase I [Curtobacterium sp. S6].	23.48	609	350	20	7	566	15	556	8e-12	79.0
tr:I0V3M7_9PSEU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.27	550	338	19	7	505	1	517	8e-12	79.0
rs:WP_046065291	DNA topoisomerase I [Pseudomonas kilonensis].	22.15	456	311	13	69	505	75	505	8e-12	79.0
rs:WP_038604253	DNA topoisomerase I [Corynebacterium atypicum].	26.80	459	262	21	102	505	93	532	8e-12	79.0
rs:WP_024059594	hypothetical protein [Varibaculum cambriense].	23.72	565	323	21	1	505	1	517	8e-12	79.0
rs:WP_042124336	DNA topoisomerase I [Pseudomonas japonica].	22.58	527	352	16	7	505	6	504	8e-12	79.0
rs:WP_025754460	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	23.02	530	346	17	7	505	6	504	8e-12	79.0
rs:WP_002521095	DNA topoisomerase I [Propionibacterium acnes].	24.17	480	284	19	80	505	64	517	8e-12	79.0
tr:W4RTY8_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE47109.1};	24.93	341	224	11	97	424	1	322	8e-12	78.6
rs:WP_043895622	DNA topoisomerase I, partial [Porphyromonas gingivalis].	26.21	248	161	5	4	243	1	234	8e-12	75.9
rs:WP_046416095	DNA topoisomerase I [Bacteroides sp. UNK.MGS-13].	23.87	532	299	20	7	504	6	465	8e-12	78.6
rs:WP_038024337	DNA topoisomerase I [Synechococcus sp. RS9916].	24.43	528	300	21	97	583	81	550	8e-12	79.0
tr:U7K4F4_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.20	471	281	17	86	505	110	555	8e-12	79.0
rs:WP_018386178	DNA topoisomerase I [Streptomyces vitaminophilus].	24.35	464	286	16	89	505	82	527	8e-12	79.0
rs:WP_046300280	DNA topoisomerase I [Mycobacterium sp. UM_Kg27].	23.05	590	354	21	7	550	21	556	8e-12	79.0
rs:WP_039168906	DNA topoisomerase I [Gallibacterium anatis].	23.58	441	285	16	88	505	93	504	8e-12	79.0
rs:WP_021108253	MULTISPECIES: DNA topoisomerase I [Propionibacterium].	24.20	471	281	17	86	505	72	517	8e-12	79.0
rs:WP_047146216	DNA topoisomerase I [Mesorhizobium sp. LC103].	23.99	546	317	22	4	505	1	492	8e-12	78.6
rs:WP_016206342	DNA topoisomerase I [Clostridium sartagoforme].	24.09	523	324	18	7	505	6	479	8e-12	78.6
rs:WP_015147956	DNA topoisomerase I [Oscillatoria acuminata].	23.87	574	348	18	46	583	29	549	8e-12	79.0
rs:WP_021861600	DNA topoisomerase [Dorea sp. CAG:105].	23.75	539	308	24	7	504	6	482	8e-12	78.6
rs:WP_019678111	DNA topoisomerase I [Ruminococcus flavefaciens].	25.62	527	314	20	7	505	5	481	8e-12	78.6
rs:WP_019424975	DNA topoisomerase I [Paenibacillus sp. OSY-SE].	25.35	426	269	15	107	504	77	481	8e-12	78.6
rs:WP_021891351	DNA topoisomerase [Bacteroides sp. CAG:20].	23.83	554	313	21	7	523	6	487	8e-12	78.6
rs:WP_032888794	DNA topoisomerase I [Pseudomonas sp. RIT357].	22.88	459	304	15	69	505	75	505	8e-12	78.6
tr:Q0BU00_GRABC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.99	542	316	25	7	505	16	504	8e-12	79.0
rs:WP_017430159	topoisomerase I [Halomonas jeotgali].	22.24	544	338	17	7	505	6	509	9e-12	78.6
rs:WP_004904017	DNA topoisomerase I [Leuconostoc citreum].	24.14	526	319	22	7	505	28	500	9e-12	78.6
rs:WP_043243916	DNA topoisomerase I [Pseudomonas alcaligenes].	23.95	430	276	15	99	505	103	504	9e-12	78.6
tr:A4N0B7_HAEIF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.13	549	330	23	3	505	2	504	9e-12	78.2
tr:A5IY64_MYCAP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.90	524	327	20	3	504	2	470	9e-12	78.2
rs:WP_044329464	DNA topoisomerase I [Mycoplasma hominis].	21.28	517	331	16	7	504	6	465	9e-12	78.2
rs:WP_005751468	topoisomerase I [Pasteurella multocida].	24.16	447	275	16	88	505	93	504	9e-12	78.6
rs:WP_043042019	DNA topoisomerase I [Pseudomonas fluorescens].	22.15	456	311	13	69	505	75	505	9e-12	78.6
rs:WP_024821701	DNA topoisomerase I [Aminobacterium mobile].	25.23	539	303	23	7	505	11	489	9e-12	78.6
rs:WP_035596172	DNA topoisomerase I [Halomonas salina].	21.02	452	324	11	69	505	80	513	9e-12	78.6
rs:WP_038641850	DNA topoisomerase I [Pasteurella multocida].	24.16	447	275	16	88	505	93	504	9e-12	78.6
rs:WP_016951059	DNA topoisomerase I [Anabaena sp. PCC 7108].	24.75	509	294	16	95	566	78	534	9e-12	78.6
rs:WP_003199646	MULTISPECIES: topoisomerase I [Pseudomonas].	22.15	456	311	13	69	505	75	505	9e-12	78.6
rs:WP_021916891	DNA topoisomerase [Brachyspira sp. CAG:484].	22.68	560	336	19	7	539	28	517	9e-12	78.6
rs:WP_016492045	DNA topoisomerase I [Pseudomonas resinovorans].	23.42	427	282	14	99	505	103	504	9e-12	78.6
rs:WP_043055226	DNA topoisomerase I, partial [Micrococcus luteus].	23.45	563	327	22	7	505	19	541	9e-12	78.6
tr:W6FUY3_NODSP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.41	508	297	15	95	566	49	505	9e-12	78.6
rs:WP_022043262	DNA topoisomerase [Bacteroides caccae CAG:21].	24.86	519	314	20	7	504	6	469	9e-12	78.6
rs:WP_013971714	MULTISPECIES: topoisomerase I [Pseudomonas].	23.02	530	346	17	7	505	6	504	9e-12	78.6
rs:WP_036901617	MULTISPECIES: DNA topoisomerase I [Propionibacterium].	24.20	471	281	17	86	505	72	517	9e-12	78.6
rs:WP_045040343	DNA topoisomerase III, partial [Photobacterium iliopiscarium].	28.07	171	111	2	393	553	1	169	9e-12	75.5
rs:WP_027349138	DNA topoisomerase I [Halotalea alkalilenta].	24.41	426	279	15	99	505	107	508	9e-12	78.6
rs:WP_039179783	DNA topoisomerase I [Halomonas hydrothermalis].	22.69	432	299	12	88	505	99	509	9e-12	78.6
rs:WP_025338324	DNA topoisomerase I [Pseudomonas sp. FGI182].	23.21	530	345	17	7	505	6	504	9e-12	78.6
rs:WP_003696216	DNA topoisomerase I [Neisseria gonorrhoeae].	25.06	431	272	13	107	505	77	488	9e-12	78.6
tr:G1V000_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.17	143	90	4	309	449	1	138	9e-12	74.7
rs:WP_036712476	hypothetical protein, partial [Paracoccus sp. 5503].	23.38	556	315	23	4	505	1	499	9e-12	78.6
rs:WP_041308816	DNA topoisomerase I [Mycoplasma agalactiae].	22.88	520	324	20	7	504	2	466	9e-12	78.2
rs:WP_022216093	DNA topoisomerase [Coprococcus sp. CAG:131].	23.42	538	309	24	7	504	31	505	9e-12	78.6
rs:WP_025236016	DNA topoisomerase I [Mannheimia varigena].	24.22	450	290	16	79	505	83	504	9e-12	78.6
rs:WP_044405059	DNA topoisomerase I [Pseudomonas sp. FeS53a].	24.05	474	300	17	99	555	103	533	9e-12	78.6
rs:WP_046615846	DNA topoisomerase I [Pseudomonas putida].	23.02	530	346	17	7	505	6	504	9e-12	78.6
tr:U7J6P3_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.20	471	281	17	86	505	110	555	9e-12	78.6
rs:WP_019888308	DNA topoisomerase I [Streptomyces purpureus].	23.02	556	325	23	7	505	15	524	9e-12	78.6
rs:WP_018226243	DNA topoisomerase I [actinobacterium SCGC AAA028-A23].	24.27	548	324	21	7	505	6	511	9e-12	78.6
rs:WP_018675058	DNA topoisomerase I [Riemerella columbina].	23.57	526	306	25	7	504	6	463	9e-12	78.6
sp:TOP1_PASMU	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.16	447	275	16	88	505	93	504	9e-12	78.6
rs:WP_016666857	DNA topoisomerase I [Propionibacterium sp. HGH0353].	24.20	471	281	17	86	505	72	517	9e-12	78.6
rs:XP_002404156	topoisomerase I, putative [Ixodes scapularis].	23.27	477	287	18	107	553	111	538	9e-12	78.6
rs:WP_012194987	DNA topoisomerase I [Prochlorococcus marinus].	24.49	535	333	15	7	504	6	506	9e-12	78.6
rs:WP_011294401	DNA topoisomerase I [Prochlorococcus marinus].	23.37	552	324	19	5	505	6	509	9e-12	78.6
rs:WP_019829856	topoisomerase I [Vibrio cholerae].	22.28	543	335	18	7	505	6	505	9e-12	78.6
rs:WP_004323870	MULTISPECIES: DNA topoisomerase I [Bacteroides].	25.10	526	304	20	7	504	6	469	9e-12	78.6
rs:WP_045211687	DNA topoisomerase I [Pseudomonas sp. 21].	24.95	461	283	17	99	541	102	517	9e-12	78.6
rs:WP_012313561	topoisomerase I [Pseudomonas putida].	22.58	527	352	16	7	505	6	504	9e-12	78.6
rs:WP_023679974	DNA topoisomerase I [Mesorhizobium sp. LSJC280B00].	25.45	550	304	24	4	505	1	492	9e-12	78.6
tr:Q05WM0_9SYNE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.43	528	300	21	97	583	96	565	9e-12	78.6
rs:WP_014697157	DNA topoisomerase I [Bifidobacterium animalis].	22.24	553	334	19	7	505	8	518	9e-12	78.6
rs:WP_027306991	DNA topoisomerase I [Candidatus Pelagibacter ubique].	23.45	597	352	23	7	569	4	529	9e-12	78.6
rs:WP_004810389	DNA topoisomerase I [Propionibacterium avidum].	24.20	471	281	17	86	505	72	517	1e-11	78.6
rs:WP_010360929	DNA topoisomerase I [Neisseria gonorrhoeae].	25.06	431	272	13	107	505	77	488	1e-11	78.6
rs:WP_030629439	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.90	559	325	22	7	505	15	527	1e-11	78.6
rs:WP_013905219	endonuclease [Pyrococcus yayanosii].	24.78	347	215	13	7	332	4	325	1e-11	78.6
rs:WP_013905219	endonuclease [Pyrococcus yayanosii].	27.71	231	124	7	330	546	783	984	1e-08	68.6
rs:WP_043695374	DNA topoisomerase I [Synechococcus sp. KORDI-49].	25.89	448	252	17	107	505	91	507	1e-11	78.6
rs:WP_032930423	DNA topoisomerase I [Mesorhizobium loti].	25.05	547	310	25	4	505	1	492	1e-11	78.6
tr:U7QC71_9CYAN	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.64	552	348	15	47	566	1	505	1e-11	78.6
rs:WP_016914091	topoisomerase I [Halomonas stevensii].	22.69	432	299	12	88	505	99	509	1e-11	78.6
rs:WP_014937682	DNA topoisomerase I [Riemerella anatipestifer].	23.91	527	304	24	7	504	6	464	1e-11	78.6
rs:WP_009560096	DNA topoisomerase I [Lactobacillus pasteurii].	22.80	522	331	17	7	504	22	495	1e-11	78.2
rs:WP_024850251	DNA topoisomerase I [Thiomicrospira kuenenii].	22.72	515	326	16	7	504	5	464	1e-11	78.6
rs:WP_026490871	DNA topoisomerase I [Butyrivibrio sp. XPD2002].	24.32	444	282	19	93	505	66	486	1e-11	78.2
tr:X1MXK9_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_L01930 {ECO:0000313|EMBL:GAI11099.1}; Flags: Fragment;	28.12	256	168	6	101	352	11	254	1e-11	75.9
rs:WP_043455798	DNA topoisomerase I, partial [Granulibacter bethesdensis].	23.99	542	316	25	7	505	5	493	1e-11	78.6
rs:WP_027433127	DNA topoisomerase I [Lachnospiraceae bacterium MD2004].	24.10	527	321	25	7	504	6	482	1e-11	78.2
rs:WP_014339360	topoisomerase I [Pseudomonas fluorescens].	22.15	456	311	13	69	505	75	505	1e-11	78.6
rs:WP_009571103	DNA topoisomerase I [Celeribacter baekdonensis].	24.05	553	316	23	4	505	1	500	1e-11	78.6
tr:K1U2L6_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC72560.1}; Flags: Fragment;	29.73	185	106	5	7	182	5	174	1e-11	74.7
rs:WP_008712829	DNA topoisomerase [Rhodococcus sp. AW25M09].	25.17	592	336	24	7	550	19	551	1e-11	78.6
rs:WP_009628079	DNA topoisomerase I [Pseudanabaena biceps].	25.90	529	284	20	89	568	72	541	1e-11	78.6
rs:WP_008023233	DNA topoisomerase I [Bacteroides xylanisolvens].	25.10	526	304	20	7	504	6	469	1e-11	78.6
tr:F4MZL4_YEREN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	27.00	400	243	16	88	474	93	456	1e-11	77.8
rs:WP_022463897	DNA topoisomerase [Clostridium sp. CAG:277].	22.85	534	317	21	7	504	9	483	1e-11	78.2
rs:WP_027617977	DNA topoisomerase I [Pseudomonas sp. URHB0015].	24.07	428	278	15	99	505	104	505	1e-11	78.6
rs:WP_046926801	DNA topoisomerase I [Streptomyces lydicus].	24.57	460	273	17	97	505	91	527	1e-11	78.6
rs:WP_009871082	Topoisomerase IA [Magnetospirillum magnetotacticum].	24.67	535	323	23	4	504	1	489	1e-11	78.6
rs:WP_014248084	DNA topoisomerase I [Azospirillum lipoferum].	23.67	545	325	19	1	505	1	494	1e-11	78.6
rs:WP_002805396	DNA topoisomerase I [Prochlorococcus marinus].	25.49	510	301	19	101	579	85	546	1e-11	78.6
rs:WP_015583347	DNA topoisomerase I [Propionibacterium avidum].	24.20	471	281	17	86	505	72	517	1e-11	78.6
rs:WP_019692747	topoisomerase I [Pseudomonas fluorescens].	22.15	456	311	13	69	505	75	505	1e-11	78.6
rs:WP_005675246	DNA topoisomerase I [Bacteroides caccae].	24.86	519	314	20	7	504	6	469	1e-11	78.2
rs:WP_043134186	hypothetical protein, partial [Paracoccus sp. 4681].	23.38	556	315	23	4	505	1	499	1e-11	78.6
rs:WP_035065874	DNA topoisomerase I [Anoxybacillus gonensis].	23.57	526	315	22	112	598	82	559	1e-11	78.2
rs:WP_013837612	DNA topoisomerase I [Isoptericola variabilis].	22.08	566	329	20	7	505	8	528	1e-11	78.6
tr:A4TWS2_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.45	550	307	28	4	505	1	495	1e-11	78.6
rs:WP_023175222	DNA topoisomerase I [Gloeobacter kilaueensis].	23.18	578	345	22	7	536	4	530	1e-11	78.2
rs:WP_044803582	DNA topoisomerase III, partial [Bacillus amyloliquefaciens].	29.61	179	116	6	3	179	4	174	1e-11	74.3
rs:WP_002627127	DNA topoisomerase I [Cystobacter fuscus].	23.23	564	330	23	7	516	88	602	1e-11	78.6
rs:WP_012817992	DNA topoisomerase III [Staphylococcus sp. CDC3].	22.32	560	328	21	38	537	46	558	1e-11	78.2
rs:WP_013145765	DNA topoisomerase I [Geobacillus sp. C56-T3].	23.11	623	379	22	7	598	6	559	1e-11	78.2
rs:WP_035113522	DNA topoisomerase I [Corynebacterium auriscanis].	25.47	530	306	25	40	505	28	532	1e-11	78.6
rs:WP_025767428	hypothetical protein [Vibrio parahaemolyticus].	24.71	526	306	19	7	495	4	476	1e-11	78.6
rs:WP_025267939	DNA topoisomerase I [Leuconostoc mesenteroides].	23.35	531	315	21	7	504	26	497	1e-11	78.2
rs:WP_003245261	topoisomerase I [Pseudomonas mendocina].	22.30	538	339	21	7	505	6	503	1e-11	78.6
rs:WP_043206689	DNA topoisomerase I [Pseudomonas putida].	22.22	540	338	17	7	505	6	504	1e-11	78.6
rs:WP_036893779	DNA topoisomerase I [Prevotella sp. S7-1-8].	23.52	523	315	17	7	504	6	468	1e-11	78.2
rs:WP_009372033	DNA topoisomerase I [Veillonella sp. oral taxon 158].	24.38	525	318	22	7	504	32	504	1e-11	78.2
rs:WP_010176358	topoisomerase I [Pseudomonas sp. PAMC 25886].	22.88	459	304	15	69	505	75	505	1e-11	78.6
rs:WP_003290000	topoisomerase I [Pseudomonas stutzeri].	22.10	525	355	16	7	505	6	502	1e-11	78.6
rs:WP_030782197	DNA topoisomerase I [Streptomyces sp. NRRL S-920].	23.02	556	325	21	7	505	15	524	1e-11	78.6
rs:WP_015593131	DNA topoisomerase I [Bacillus sp. 1NLA3E].	24.23	421	269	16	112	504	82	480	1e-11	78.2
rs:WP_006197444	DNA topoisomerase I [Nodularia spumigena].	24.41	508	297	15	95	566	78	534	1e-11	78.6
rs:WP_046516925	DNA topoisomerase I, partial [Cryomorphaceae bacterium ASP10-05a].	26.29	445	265	16	89	505	58	467	1e-11	78.2
rs:WP_009230497	DNA topoisomerase I [Prevotella sp. oral taxon 317].	24.36	583	332	21	7	552	6	516	1e-11	78.2
rs:WP_024078549	DNA topoisomerase I [Magnetospirillum gryphiswaldense].	25.45	550	307	28	4	505	1	495	1e-11	78.6
rs:WP_013523392	MULTISPECIES: DNA topoisomerase I [Geobacillus].	23.43	623	377	23	7	598	6	559	1e-11	78.2
rs:WP_015114554	DNA topoisomerase I [Nostoc sp. PCC 7107].	23.56	433	280	15	103	505	78	489	1e-11	78.2
rs:WP_028656482	DNA topoisomerase I [Nocardioides sp. J54].	23.36	548	334	21	7	505	6	516	1e-11	78.6
rs:WP_040008887	DNA topoisomerase I [Francisella sp. FSC1006].	23.35	544	318	18	7	505	6	495	1e-11	78.2
tr:V4QWD7_STRIN	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESR08798.1}; Flags: Fragment;	29.14	151	89	3	381	530	44	177	1e-11	74.7
rs:WP_033700418	DNA topoisomerase I [Pseudomonas sp. WCS358].	22.77	527	351	16	7	505	6	504	1e-11	78.6
tr:A0A0B8R7W6_LISMN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.33	376	236	13	112	466	82	437	1e-11	77.4
rs:WP_028508714	DNA topoisomerase I [Ruminococcaceae bacterium AB4001].	24.36	550	322	19	7	512	6	505	1e-11	78.2
rs:WP_037107832	DNA topoisomerase I [Rhizobium sp. OK665].	25.18	552	306	26	4	505	1	495	1e-11	78.6
rs:WP_007156365	DNA topoisomerase I [Oribacterium sinus].	25.05	527	314	21	7	504	6	480	1e-11	78.2
rs:WP_036549903	DNA topoisomerase I [Nitrincola lacisaponensis].	21.44	541	351	15	5	505	4	510	1e-11	78.6
rs:WP_027596626	DNA topoisomerase I [Pseudomonas sp. LAIL14HWK12:I7].	23.02	530	346	17	7	505	6	504	1e-11	78.2
rs:WP_022859916	DNA topoisomerase I [Bifidobacterium magnum].	22.32	560	322	23	7	505	8	515	1e-11	78.6
rs:WP_008380089	DNA topoisomerase I [Gordonia malaquae].	22.64	561	340	21	7	510	15	538	1e-11	78.6
rs:WP_012575317	DNA topoisomerase I [Anoxybacillus flavithermus].	23.72	527	313	22	112	598	82	559	1e-11	78.2
rs:WP_039589079	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	22.44	459	306	14	69	505	75	505	1e-11	78.2
tr:Q98Q95_MYCPU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.84	537	295	22	7	504	11	472	1e-11	78.2
rs:WP_022264915	DNA topoisomerase [Clostridium sp. CAG:352].	23.36	535	327	20	7	505	5	492	1e-11	78.2
rs:WP_011847016	topoisomerase I [Shewanella baltica].	23.11	541	335	18	7	505	6	507	1e-11	78.2
rs:WP_015489632	DNA topoisomerase I A [Clavibacter michiganensis].	22.50	551	335	18	7	505	8	518	1e-11	78.6
rs:WP_027921688	DNA topoisomerase I [Pseudomonas sp. URMO17WK12:I12].	21.93	456	312	13	69	505	75	505	1e-11	78.2
rs:WP_019776020	hypothetical protein, partial [Streptococcus sobrinus].	27.23	224	145	5	5	219	3	217	1e-11	74.7
rs:WP_025951077	DNA topoisomerase I [Geobacillus thermocatenulatus].	22.95	623	380	22	7	598	6	559	1e-11	78.2
rs:WP_009106404	DNA topoisomerase I [Desulfovibrio sp. U5L].	25.23	440	288	14	88	505	58	478	1e-11	78.2
rs:WP_013546559	DNA topoisomerase I [Bacteroides helcogenes].	23.18	522	320	17	7	504	6	470	1e-11	78.2
rs:WP_010359499	DNA topoisomerase I [Neisseria gonorrhoeae].	25.06	431	272	13	107	505	77	488	1e-11	78.2
rs:WP_027966615	DNA topoisomerase I [Halomonas halocynthiae].	23.05	538	342	19	7	505	6	510	1e-11	78.2
rs:WP_013447026	DNA topoisomerase I [Riemerella anatipestifer].	23.72	527	305	24	7	504	6	464	1e-11	78.2
rs:WP_016534517	DNA topoisomerase I subunit omega [Pasteurella multocida].	24.16	447	275	16	88	505	93	504	1e-11	78.2
rs:WP_016910752	DNA topoisomerase I [Staphylococcus vitulinus].	24.02	533	311	20	7	504	6	479	1e-11	78.2
tr:W6MAU3_9GAMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.42	564	289	25	7	505	6	508	1e-11	78.2
rs:WP_007450295	DNA topoisomerase I [Streptomyces sp. W007].	22.90	559	325	21	7	505	15	527	1e-11	78.2
rs:WP_022037788	DNA topoisomerase [Ruminococcus gnavus CAG:126].	23.48	528	322	22	7	504	6	481	1e-11	78.2
rs:WP_008028483	topoisomerase I [Pseudomonas sp. GM60].	21.93	456	312	13	69	505	75	505	1e-11	78.2
rs:WP_017337559	topoisomerase I [Pseudomonas fluorescens].	21.93	456	312	13	69	505	75	505	1e-11	78.2
rs:WP_022378022	GTP-sensing transcriptional pleiotropic repressor CodY [Clostridium sp. CAG:62].	25.56	532	304	25	7	504	6	479	1e-11	78.2
rs:WP_043267321	DNA topoisomerase I [Pseudomonas sp. AAC].	24.51	461	285	16	99	541	103	518	1e-11	78.2
rs:WP_041020100	DNA topoisomerase I [Pseudomonas sp. SHC52].	22.44	459	306	14	69	505	75	505	1e-11	78.2
rs:WP_038065387	hypothetical protein, partial [Thermodesulfovibrio thiophilus].	24.02	537	323	24	7	505	5	494	1e-11	78.2
rs:YP_009052166	putative DNA topoisomerase IA [Aureococcus anophagefferens virus].	24.47	474	289	21	89	543	55	478	1e-11	78.2
rs:WP_022869109	DNA topoisomerase I [Actinomyces vaccimaxillae].	23.01	565	333	21	1	505	1	523	1e-11	78.2
rs:WP_009612532	DNA topoisomerase I [actinobacterium SCGC AAA027-L06].	24.27	548	324	21	7	505	6	511	1e-11	78.2
rs:WP_039154270	DNA topoisomerase I [Gallibacterium anatis].	23.58	441	285	16	88	505	93	504	1e-11	78.2
rs:WP_032851656	DNA topoisomerase I [Pasteurella multocida].	24.16	447	275	16	88	505	93	504	1e-11	78.2
rs:WP_022289901	DNA topoisomerase [Oscillibacter sp. CAG:155].	21.62	532	344	17	1	505	1	486	1e-11	78.2
rs:WP_003218973	MULTISPECIES: topoisomerase I [Pseudomonas].	22.88	459	304	15	69	505	75	505	1e-11	78.2
rs:WP_025636650	DNA topoisomerase I [Vibrio parahaemolyticus].	22.61	544	331	21	7	505	6	504	1e-11	78.2
rs:WP_003456255	DNA topoisomerase I [Pseudomonas pseudoalcaligenes].	24.36	427	278	14	99	505	102	503	1e-11	78.2
rs:WP_029651254	DNA topoisomerase I [Methylocystis sp. SB2].	24.10	556	319	24	4	510	1	502	1e-11	78.2
rs:WP_028243884	DNA topoisomerase I [Pseudobutyrivibrio ruminis].	23.89	494	308	21	47	504	21	482	1e-11	78.2
rs:WP_004821709	DNA topoisomerase I [Peptoniphilus indolicus].	24.60	630	371	23	7	606	6	561	1e-11	78.2
rs:WP_038186134	DNA topoisomerase I [Vibrio rhizosphaerae].	23.91	460	297	19	69	505	75	504	1e-11	78.2
rs:WP_036317285	DNA topoisomerase I [Micrococcus luteus].	23.27	563	328	22	7	505	19	541	1e-11	78.2
rs:WP_027919555	DNA topoisomerase I [Pseudomonas sp. URMO17WK12:I8].	23.60	428	280	14	99	505	104	505	1e-11	78.2
rs:WP_006086246	topoisomerase I [Shewanella baltica].	23.11	541	335	18	7	505	6	507	1e-11	78.2
rs:WP_017477200	topoisomerase I [Pseudomonas sp. PAMC 26793].	22.88	459	304	15	69	505	75	505	1e-11	78.2
rs:WP_036875017	hypothetical protein, partial [Prevotella nigrescens].	26.29	213	134	5	331	531	1	202	1e-11	76.6
rs:WP_016854570	topoisomerase I [Halomonas smyrnensis].	22.52	453	316	12	69	505	80	513	1e-11	78.2
rs:WP_012855440	DNA topoisomerase I [Mycoplasma hominis].	21.28	517	331	16	7	504	6	465	1e-11	77.8
rs:XP_004957260	PREDICTED: DNA topoisomerase 3-beta [Setaria italica].	23.82	529	338	22	1	498	1	495	1e-11	78.2
rs:WP_043494493	DNA topoisomerase I [Streptomyces ghanaensis].	23.57	560	318	23	7	505	15	525	1e-11	78.2
rs:WP_019365904	topoisomerase I [Pseudomonas luteola].	22.88	437	293	14	88	505	93	504	1e-11	78.2
rs:WP_009839581	topoisomerase I [Pseudoalteromonas tunicata].	22.04	549	332	20	7	505	6	508	1e-11	78.2
rs:WP_022451857	DNA topoisomerase [Clostridium sp. CAG:269].	24.00	425	275	15	107	504	77	480	1e-11	77.8
tr:K9YA52_HALP7	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.38	526	316	16	89	579	72	545	1e-11	78.2
rs:WP_006996844	DNA topoisomerase I [Candidatus Pelagibacter ubique].	23.33	600	355	23	4	569	1	529	1e-11	78.2
rs:WP_022470161	DNA topoisomerase III [Bacteroides thetaiotaomicron CAG:40].	28.77	219	142	9	275	485	16	228	1e-11	75.1
rs:WP_021978486	DNA topoisomerase [Clostridium sp. CAG:793].	23.60	534	316	18	7	504	6	483	1e-11	77.8
rs:WP_005824022	topoisomerase I [Actinobacillus minor].	24.44	446	278	19	86	505	92	504	1e-11	78.2
rs:WP_022408208	DNA topoisomerase [Clostridium sp. CAG:354].	23.83	533	312	22	7	504	6	479	1e-11	77.8
rs:WP_016218473	DNA topoisomerase I [Dorea sp. 5-2].	23.30	442	286	15	93	504	63	481	1e-11	77.8
rs:WP_025905317	DNA topoisomerase I [Staphylococcus sciuri].	24.35	538	303	22	7	504	6	479	1e-11	77.8
rs:WP_027192232	DNA topoisomerase I [Desulfovibrio putealis].	25.05	527	316	19	7	505	6	481	1e-11	78.2
rs:WP_041596475	DNA topoisomerase I, partial [Halothece sp. PCC 7418].	23.38	526	316	16	89	579	72	545	1e-11	78.2
rs:WP_013110457	DNA topoisomerase I [Planctomyces limnophilus].	24.07	540	333	18	7	505	10	513	1e-11	78.2
rs:WP_018551170	DNA topoisomerase I [Streptomyces sp. ATexAB-D23].	22.90	559	325	22	7	505	15	527	1e-11	78.2
rs:WP_040275379	DNA topoisomerase I [Streptomonospora alba].	24.04	520	321	22	38	505	42	539	1e-11	78.2
rs:WP_014847639	DNA topoisomerase I [Propionibacterium propionicum].	24.36	472	279	16	89	505	76	524	1e-11	78.2
rs:WP_030633085	DNA topoisomerase I [Streptomyces albus].	23.26	559	323	22	7	505	15	527	1e-11	78.2
rs:WP_008037710	topoisomerase I [Pseudomonas sp. GM67].	21.93	456	312	13	69	505	75	505	1e-11	78.2
rs:WP_030383632	DNA topoisomerase I [Streptomyces sp. NRRL S-241].	23.08	559	321	23	7	505	15	524	1e-11	78.2
rs:WP_047319885	DNA topoisomerase I [Mycobacterium heraklionense].	23.03	595	352	21	7	550	21	560	1e-11	78.2
rs:WP_010797697	DNA topoisomerase 1 [Pseudomonas sp. HPB0071].	22.88	437	293	14	88	505	93	504	1e-11	78.2
rs:WP_011230711	MULTISPECIES: DNA topoisomerase I [Geobacillus].	22.95	623	380	22	7	598	6	559	1e-11	77.8
rs:WP_035147642	hypothetical protein, partial [Lactobacillus sakei].	24.00	375	251	15	65	423	20	376	1e-11	77.8
rs:WP_006081959	topoisomerase I [Shewanella baltica].	23.11	541	335	18	7	505	6	507	1e-11	78.2
rs:WP_033025076	DNA topoisomerase I [Geobacillus sp. CAMR5420].	22.95	623	380	22	7	598	6	559	1e-11	77.8
rs:WP_035107281	DNA topoisomerase I [Corynebacterium camporealensis].	25.57	442	265	19	107	505	97	517	1e-11	78.2
rs:WP_004490023	DNA topoisomerase I [Leptospira santarosai].	22.94	523	321	17	7	505	5	469	1e-11	77.8
rs:WP_019470223	MULTISPECIES: topoisomerase I [Pseudomonas].	22.83	530	347	17	7	505	6	504	1e-11	78.2
rs:WP_022796267	DNA topoisomerase I [Bavariicoccus seileri].	23.03	521	330	16	7	504	7	479	1e-11	77.8
rs:WP_003690297	DNA topoisomerase I [Neisseria gonorrhoeae].	25.17	433	269	15	107	505	77	488	1e-11	77.8
rs:WP_034214990	DNA topoisomerase I [Lachnoanaerobaculum sp. MSX33].	25.57	438	275	14	97	504	67	483	1e-11	77.8
rs:WP_013021919	DNA topoisomerase I [Mycoplasma agalactiae].	22.52	524	329	20	3	504	2	470	1e-11	77.8
rs:XP_001950527	PREDICTED: DNA topoisomerase 3-alpha [Acyrthosiphon pisum].	23.72	506	328	18	82	569	114	579	1e-11	78.2
rs:WP_040708059	DNA topoisomerase I, partial [Oceanibaculum indicum].	24.49	543	312	27	7	505	4	492	1e-11	78.2
rs:WP_002321672	topoisomerase [Enterococcus faecium].	38.98	118	62	5	5	118	3	114	1e-11	72.8
rs:WP_027425646	DNA topoisomerase I [Lachnospiraceae bacterium NC2004].	24.52	571	334	27	8	553	1	499	1e-11	77.8
rs:WP_014391063	topoisomerase I [Pasteurella multocida].	24.16	447	275	16	88	505	93	504	1e-11	78.2
rs:WP_043079487	DNA topoisomerase I [Mycobacterium immunogenum].	24.73	469	282	15	86	504	69	516	1e-11	78.2
tr:U2J849_PORGN	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERJ82416.1}; Flags: Fragment;	26.10	249	155	9	178	420	1	226	1e-11	74.7
rs:WP_004312554	toprim domain protein, partial [Bacteroides xylanisolvens].	26.87	227	144	5	6	224	3	215	1e-11	75.1
rs:WP_005208330	DNA topoisomerase I [Gordonia sputi].	22.93	580	351	19	7	535	19	553	1e-11	78.2
rs:WP_028035012	DNA topoisomerase I [Chelativorans sp. J32].	23.90	544	320	24	4	505	1	492	1e-11	77.8
rs:WP_015023560	DNA topoisomerase I [Psychroflexus torquis].	23.33	540	312	23	7	512	6	477	1e-11	78.2
rs:WP_012361083	DNA topoisomerase I [Corynebacterium urealyticum].	24.74	477	284	18	86	505	69	527	1e-11	78.2
rs:WP_015382009	DNA topoisomerase I [Corynebacterium urealyticum].	24.74	477	284	18	86	505	69	527	1e-11	78.2
rs:WP_037011197	DNA topoisomerase I [Pseudomonas lutea].	23.25	542	330	21	7	505	6	504	1e-11	77.8
rs:WP_019622251	topoisomerase I [Amphritea japonica].	22.98	470	309	17	69	512	81	523	1e-11	77.8
rs:WP_017519284	topoisomerase I [Pseudomonas nitroreducens].	24.73	461	284	17	99	541	102	517	1e-11	77.8
rs:WP_024603974	DNA topoisomerase I [Pseudoalteromonas haloplanktis].	22.76	435	296	13	88	505	96	507	1e-11	77.8
rs:WP_040848521	DNA topoisomerase I, partial [Thiothrix flexilis].	24.91	534	320	19	7	505	6	493	1e-11	77.8
rs:WP_044525682	DNA topoisomerase I [Francisella philomiragia].	22.45	548	318	21	7	505	6	495	1e-11	77.8
rs:WP_003690118	DNA topoisomerase I [Neisseria gonorrhoeae].	25.06	431	272	13	107	505	77	488	1e-11	77.8
rs:WP_017805692	topoisomerase I [Avibacterium paragallinarum].	24.55	448	272	18	88	505	93	504	2e-11	77.8
rs:WP_035520262	DNA topoisomerase I [Haemophilus parasuis].	23.57	454	288	18	79	505	85	506	2e-11	77.8
rs:WP_010996931	DNA topoisomerase I [Nostoc sp. PCC 7120].	24.40	504	302	14	95	566	78	534	2e-11	77.8
rs:WP_024684404	DNA topoisomerase I [Pseudomonas syringae].	23.14	458	304	14	69	505	75	505	2e-11	77.8
rs:WP_004491528	DNA topoisomerase I [Leptospira santarosai].	23.14	523	324	18	5	505	3	469	2e-11	77.4
rs:WP_022339030	DNA topoisomerase [Bacteroides sp. CAG:714].	22.64	605	362	23	7	570	6	545	2e-11	77.8
rs:WP_011823237	DNA topoisomerase I [Prochlorococcus marinus].	23.37	552	324	19	5	505	6	509	2e-11	77.8
rs:WP_030046534	DNA topoisomerase I [Streptomyces peruviensis].	23.60	555	324	22	7	505	15	525	2e-11	77.8
rs:WP_024503572	DNA topoisomerase I [Mesorhizobium ciceri].	24.07	540	324	22	4	505	1	492	2e-11	77.8
tr:F3GFX9_PSESJ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.14	458	304	14	69	505	75	505	2e-11	77.8
rs:WP_035903648	DNA topoisomerase I [Knoellia subterranea].	22.34	546	341	18	7	505	11	520	2e-11	77.8
rs:WP_022781580	DNA topoisomerase I [Lachnospiraceae bacterium NK4A136].	23.21	530	321	22	7	504	6	481	2e-11	77.8
rs:WP_005194610	DNA topoisomerase I [Gordonia rubripertincta].	22.91	550	336	18	7	505	18	530	2e-11	78.2
rs:WP_024662799	DNA topoisomerase I [Pseudomonas syringae].	23.14	458	304	14	69	505	75	505	2e-11	77.8
tr:N0BDX9_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.75	493	270	17	80	505	76	534	2e-11	77.8
rs:WP_032099733	DNA topoisomerase I [Anoxybacillus flavithermus].	23.57	526	315	22	112	598	82	559	2e-11	77.8
rs:WP_010665160	DNA topoisomerase I [Marinilabilia salmonicolor].	23.85	520	318	18	7	505	13	475	2e-11	77.8
rs:WP_016201111	DNA topoisomerase I [Bacillus nealsonii].	24.82	423	264	17	112	504	83	481	2e-11	77.8
rs:WP_010181533	DNA topoisomerase I [Aquimarina agarilytica].	27.50	440	246	23	107	512	77	477	2e-11	77.8
rs:WP_024307541	DNA topoisomerase I [Pseudomonas sp. P818].	22.30	538	339	21	7	505	6	503	2e-11	77.8
rs:WP_022223943	DNA topoisomerase [Clostridium sp. CAG:253].	23.21	530	320	22	7	504	6	480	2e-11	77.8
rs:WP_025128846	DNA topoisomerase I [Pseudomonas sp. PH1b].	22.60	531	348	18	7	505	6	505	2e-11	77.8
rs:WP_020172467	DNA topoisomerase I [Gordonia polyisoprenivorans].	23.41	551	336	19	7	505	19	535	2e-11	77.8
rs:WP_022479784	DNA topoisomerase I [Prevotella sp. CAG:891].	23.86	528	310	20	7	505	6	470	2e-11	77.8
rs:WP_047227206	DNA topoisomerase I [Pseudomonas brassicacearum].	21.93	456	312	13	69	505	75	505	2e-11	77.8
rs:WP_016660865	DNA topoisomerase I [Bacteroides stercoris].	23.75	522	316	18	7	504	6	469	2e-11	77.8
tr:A0A0A2BV50_9PROC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.46	507	294	17	97	566	61	515	2e-11	77.8
rs:WP_029457032	DNA topoisomerase I [Desulfovibrio alcoholivorans].	24.04	520	327	17	7	505	6	478	2e-11	77.8
rs:WP_021919504	DNA topoisomerase [Firmicutes bacterium CAG:114].	22.80	535	333	21	1	505	1	485	2e-11	77.8
rs:WP_004417186	DNA topoisomerase I [Pseudomonas syringae].	23.14	458	304	14	69	505	75	505	2e-11	77.8
rs:WP_036918120	MULTISPECIES: DNA topoisomerase I, partial [Prochlorococcus].	24.46	507	294	17	97	566	81	535	2e-11	77.8
rs:WP_036391367	DNA topoisomerase I [Mycobacterium farcinogenes].	24.61	512	300	18	86	550	81	553	2e-11	77.8
rs:WP_020002660	DNA topoisomerase I [Mycoplasma hominis].	21.08	517	332	16	7	504	6	465	2e-11	77.4
rs:WP_006372355	DNA topoisomerase I [Gordonia polyisoprenivorans].	23.41	551	336	19	7	505	19	535	2e-11	77.8
rs:WP_028576602	DNA topoisomerase I [Desulfomicrobium escambiense].	24.55	448	281	16	88	505	58	478	2e-11	77.8
rs:WP_021669643	DNA topoisomerase I [Prevotella disiens].	24.39	578	343	22	7	552	25	540	2e-11	77.8
rs:WP_007847280	DNA topoisomerase I [Bacteroides dorei].	23.28	524	316	22	7	504	6	469	2e-11	77.8
tr:W2CME8_9PORP	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETK08424.1};	29.51	183	115	4	368	539	16	195	2e-11	74.7
rs:WP_013725660	DNA topoisomerase I [Clostridium botulinum].	23.57	543	332	21	7	517	6	497	2e-11	77.8
rs:WP_004472265	DNA topoisomerase I [Leptospira santarosai].	23.14	523	324	18	5	505	3	469	2e-11	77.4
rs:WP_041434247	DNA topoisomerase I [Thermocrinis albus].	24.14	551	323	21	7	544	4	472	2e-11	77.4
rs:WP_030087088	DNA topoisomerase I [Streptomyces baarnensis].	23.26	559	323	22	7	505	15	527	2e-11	77.8
rs:WP_016568498	DNA topoisomerase I [Pseudomonas syringae].	23.14	458	304	14	69	505	75	505	2e-11	77.8
tr:D6A7S0_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.57	560	318	23	7	505	28	538	2e-11	77.8
rs:WP_009661275	DNA topoisomerase I [Veillonella sp. ACP1].	23.92	581	347	24	7	564	69	577	2e-11	77.8
rs:WP_015756822	DNA topoisomerase I [Desulfotomaculum acetoxidans].	22.62	535	329	22	3	505	2	483	2e-11	77.8
tr:K2JZ46_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.49	543	312	27	7	505	4	492	2e-11	77.8
rs:WP_008023008	topoisomerase I [Pseudomonas sp. GM55].	22.95	427	284	14	99	505	104	505	2e-11	77.8
rs:WP_011282147	DNA topoisomerase I [Candidatus Pelagibacter ubique].	23.45	597	352	23	7	569	4	529	2e-11	77.8
rs:WP_019009533	DNA topoisomerase I [Deinococcus aquatilis].	24.28	552	326	24	5	505	9	519	2e-11	77.8
rs:WP_007166600	DNA topoisomerase I [Mycobacterium parascrofulaceum].	24.63	467	287	17	86	504	85	534	2e-11	77.8
rs:WP_029300089	DNA topoisomerase I [Pseudomonas fluorescens].	22.54	457	308	14	69	505	75	505	2e-11	77.8
rs:WP_008655482	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.28	524	316	22	7	504	6	469	2e-11	77.8
gp:CP003183_2502	DNA topoisomerase I [Granulibacter bethesdensis CGDNIH2]	24.17	542	315	25	7	505	16	504	2e-11	77.8
rs:WP_014668030	topoisomerase I [Pasteurella multocida].	24.16	447	275	16	88	505	93	504	2e-11	77.8
rs:WP_037995540	DNA topoisomerase III, partial [Tannerella sp. oral taxon BU063].	29.51	183	115	4	368	539	21	200	2e-11	74.7
rs:WP_030019286	DNA topoisomerase I [Streptomyces monomycini].	24.57	460	273	18	97	505	91	527	2e-11	77.8
rs:WP_047207619	DNA topoisomerase I [Mycoplasma hominis].	21.28	517	331	16	7	504	6	465	2e-11	77.4
rs:WP_025407270	DNA topoisomerase I [Borrelia parkeri].	23.17	600	351	25	7	561	7	541	2e-11	77.8
rs:WP_046306525	DNA topoisomerase I [Grimontia sp. AD028].	22.81	456	307	14	69	505	74	503	2e-11	77.8
rs:WP_038125361	DNA topoisomerase I [Veillonella sp. 3_1_44].	24.67	527	314	24	7	504	76	548	2e-11	77.8
rs:WP_012628662	DNA topoisomerase I [Cyanothece sp. PCC 7425].	23.05	525	333	15	89	583	72	555	2e-11	77.8
rs:WP_008394635	MULTISPECIES: DNA topoisomerase I [Leptospira].	22.94	523	325	18	5	505	3	469	2e-11	77.4
rs:WP_007841944	DNA topoisomerase I [Bacteroides dorei].	23.28	524	316	22	7	504	6	469	2e-11	77.8
rs:WP_035944809	DNA topoisomerase I [Frankia sp. Iso899].	24.19	554	330	21	7	505	2	520	2e-11	77.8
rs:WP_001716542	DNA topoisomerase III, partial [Salmonella enterica].	26.56	305	197	10	7	301	4	291	2e-11	75.1
tr:U2PF89_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.67	527	312	19	7	505	15	484	2e-11	77.4
rs:WP_003865910	DNA topoisomerase I [Holdemanella biformis].	25.90	529	303	20	7	505	6	475	2e-11	77.4
rs:WP_021148177	DNA topoisomerase I [Veillonella parvula].	24.19	525	319	22	7	504	76	548	2e-11	77.8
rs:WP_027698447	DNA topoisomerase I [Weissella oryzae].	23.28	524	325	18	7	504	27	499	2e-11	77.4
rs:WP_002762881	DNA topoisomerase I [Leptospira borgpetersenii].	23.15	527	323	18	1	504	1	468	2e-11	77.4
rs:WP_042380537	DNA topoisomerase I [Geobacillus kaustophilus].	22.95	623	380	22	7	598	6	559	2e-11	77.4
rs:WP_039240575	DNA topoisomerase I [Clostridium botulinum].	23.57	543	332	21	7	517	6	497	2e-11	77.4
rs:WP_016986750	topoisomerase I [Pseudomonas fluorescens].	23.31	459	302	16	69	505	75	505	2e-11	77.8
rs:WP_021019037	topoisomerase I [Vibrio gazogenes].	23.19	457	304	16	69	505	75	504	2e-11	77.8
rs:WP_022177538	DNA topoisomerase [Oscillibacter sp. CAG:241].	23.19	539	312	22	7	505	10	486	2e-11	77.4
rs:WP_011892291	DNA topoisomerase I [Mycobacterium gilvum].	23.83	470	288	15	86	504	82	532	2e-11	77.8
rs:WP_044420529	DNA topoisomerase I [Mycoplasma hominis].	21.08	517	332	16	7	504	6	465	2e-11	77.4
rs:WP_007986365	topoisomerase I [Pseudomonas sp. GM48].	22.95	427	284	14	99	505	104	505	2e-11	77.8
rs:WP_020169475	DNA topoisomerase I [Candidatus Pelagibacter ubique].	23.33	600	355	24	4	569	1	529	2e-11	77.8
rs:WP_031482602	DNA topoisomerase I [Streptomyces bicolor].	23.30	558	322	23	7	505	15	525	2e-11	77.8
tr:D3SM80_THEAH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.14	551	323	21	7	544	5	473	2e-11	77.0
rs:WP_002244762	DNA topoisomerase I [Neisseria meningitidis].	24.53	534	317	21	7	505	6	488	2e-11	77.4
rs:WP_007854957	DNA topoisomerase I [Bacteroides dorei].	23.28	524	316	22	7	504	6	469	2e-11	77.8
rs:WP_033117512	DNA topoisomerase I [Intestinimonas butyriciproducens].	23.32	536	328	21	1	505	1	484	2e-11	77.4
rs:WP_044009045	DNA topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	2e-11	77.8
rs:WP_033609624	topoisomerase I, partial [Lactobacillus plantarum].	30.69	202	124	7	375	563	1	199	2e-11	74.3
rs:WP_012498147	DNA topoisomerase I [Mycoplasma arthritidis].	24.60	435	271	18	93	504	65	465	2e-11	77.4
rs:WP_003703296	DNA topoisomerase I [Neisseria gonorrhoeae].	25.17	433	269	15	107	505	77	488	2e-11	77.4
rs:WP_004243046	topoisomerase I [Proteus mirabilis].	22.35	537	335	19	7	505	6	498	2e-11	77.8
rs:WP_011451980	DNA topoisomerase I [Neorickettsia sennetsu].	23.49	613	365	26	4	580	1	545	2e-11	77.4
rs:WP_026657198	DNA topoisomerase IA [Acholeplasma palmae].	25.21	599	340	28	7	580	6	521	2e-11	77.4
rs:WP_021444458	hypothetical protein, partial [Pseudomonas sp. EGD-AK9].	27.55	196	124	4	7	193	4	190	2e-11	73.9
rs:WP_037345451	DNA topoisomerase I [Sciscionella sp. SE31].	23.26	546	337	19	7	505	25	535	2e-11	77.8
rs:WP_008674276	DNA topoisomerase I [Bacteroides sp. 9_1_42FAA].	23.28	524	316	22	7	504	6	469	2e-11	77.4
rs:WP_046605482	DNA topoisomerase I [Neorhizobium galegae].	23.91	548	318	24	4	505	1	495	2e-11	77.8
rs:WP_046609957	DNA topoisomerase I [Neorhizobium galegae].	23.91	548	318	24	4	505	1	495	2e-11	77.8
rs:WP_013472919	DNA topoisomerase I [Mycobacterium gilvum].	23.83	470	288	15	86	504	82	532	2e-11	77.8
rs:WP_020005517	DNA topoisomerase I [Brachyspira innocens].	23.64	571	340	22	7	553	30	528	2e-11	77.4
rs:WP_021115833	DNA topoisomerase I [Haemophilus parasuis].	23.57	454	288	18	79	505	85	506	2e-11	77.8
rs:WP_027104711	DNA topoisomerase I [Lachnospiraceae bacterium V9D3004].	21.48	526	334	19	7	504	6	480	2e-11	77.4
rs:WP_043367683	DNA topoisomerase I [Mycobacterium mageritense].	24.56	513	299	19	86	550	81	553	2e-11	77.8
rs:WP_012739047	DNA topoisomerase I [[Eubacterium] eligens].	24.58	541	299	26	7	504	6	480	2e-11	77.4
rs:WP_014264447	DNA topoisomerase [Granulicella mallensis].	24.45	458	267	19	7	430	6	418	2e-11	77.8
rs:WP_021716824	DNA topoisomerase [Phascolarctobacterium sp. CAG:266].	25.24	630	360	26	7	599	6	561	2e-11	77.4
rs:WP_041321243	DNA topoisomerase I [Hyphomicrobium denitrificans].	24.75	493	270	17	80	505	46	504	2e-11	77.8
rs:WP_011472692	DNA topoisomerase I [Rhodopseudomonas palustris].	23.09	537	333	20	4	505	1	492	2e-11	77.8
rs:WP_027739698	DNA topoisomerase I [Streptomyces sp. CNT360].	24.46	466	274	20	97	505	90	534	2e-11	77.8
rs:WP_004483035	DNA topoisomerase I [Leptospira santarosai].	23.14	523	324	18	5	505	3	469	2e-11	77.4
rs:WP_036438960	DNA topoisomerase I [Mycoplasma hominis].	21.08	517	332	16	7	504	6	465	2e-11	77.4
rs:WP_034096476	MULTISPECIES: DNA topoisomerase I [Pseudomonas fluorescens group].	22.22	459	307	14	69	505	75	505	2e-11	77.4
rs:WP_043247813	DNA topoisomerase I [Streptomyces vinaceus].	22.90	559	325	21	7	505	15	527	2e-11	77.8
rs:WP_014358786	DNA topoisomerase I [Gordonia polyisoprenivorans].	23.41	551	336	19	7	505	19	535	2e-11	77.8
rs:WP_005883933	DNA topoisomerase I [Brevibacterium mcbrellneri].	25.59	551	324	20	7	505	10	526	2e-11	77.8
rs:WP_036885247	hypothetical protein, partial [Prevotella disiens].	26.07	234	148	7	331	552	1	221	2e-11	76.3
rs:WP_003412162	topoisomerase I [Pseudomonas syringae].	22.81	456	308	13	69	505	75	505	2e-11	77.4
rs:WP_036457573	DNA topoisomerase I [Mycobacterium sp. UM_WGJ].	22.88	590	355	21	7	550	15	550	2e-11	77.8
rs:WP_015095955	DNA topoisomerase I [Pseudomonas sp. UW4].	22.95	427	284	14	99	505	104	505	2e-11	77.4
rs:WP_042366602	DNA topoisomerase I [Bacteroidaceae bacterium MS4].	23.06	516	327	15	7	504	6	469	2e-11	77.4
rs:WP_018669350	DNA topoisomerase I [Bacteroides gallinarum].	23.85	524	313	19	7	504	6	469	2e-11	77.4
rs:WP_010363005	DNA topoisomerase I [Xanthomonas vasicola].	23.77	488	318	19	43	505	25	483	2e-11	77.4
tr:S7SXQ4_9BACI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.95	623	380	22	7	598	29	582	2e-11	77.4
rs:WP_046252353	DNA topoisomerase I [Mycobacterium chelonae].	24.68	470	281	16	86	504	69	516	2e-11	77.4
rs:WP_030095868	DNA topoisomerase I [Mycobacterium abscessus].	24.68	470	281	16	86	504	69	516	2e-11	77.4
rs:WP_019959258	DNA topoisomerase I [Vitreoscilla stercoraria].	24.21	537	317	19	7	505	6	490	2e-11	77.4
rs:WP_018358151	hypothetical protein [Porphyromonas levii].	23.64	516	318	20	7	504	6	463	2e-11	77.4
rs:WP_041464266	DNA topoisomerase I [Clavibacter michiganensis].	22.20	554	333	18	7	505	8	518	2e-11	77.8
gpu:CP009515_2176	DNA topoisomerase I [Methanosarcina lacustris Z-7289]	22.97	566	359	21	8	548	6	519	2e-11	77.4
rs:WP_036937101	DNA topoisomerase I [Proteus vulgaris].	22.91	537	332	20	7	505	6	498	2e-11	77.4
rs:WP_011819815	DNA topoisomerase I [Prochlorococcus marinus].	24.94	441	277	15	101	505	85	507	2e-11	77.4
tr:J6FF50_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJY17018.1}; Flags: Fragment;	29.90	194	127	5	52	243	1	187	2e-11	73.9
rs:WP_021845568	DNA topoisomerase [Blautia hydrogenotrophica CAG:147].	23.25	443	284	16	93	504	63	480	2e-11	77.4
rs:WP_043319020	DNA topoisomerase I [Pseudomonas sp. PI1].	24.51	461	285	16	99	541	103	518	2e-11	77.4
rs:WP_007974049	topoisomerase I [Pseudomonas sp. GM33].	22.95	427	284	14	99	505	104	505	2e-11	77.4
tr:D3D5Q6_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.57	560	323	21	7	505	50	565	2e-11	77.8
rs:WP_018414164	DNA topoisomerase I [Candidatus Pelagibacter ubique].	23.45	597	352	23	7	569	4	529	2e-11	77.4
rs:WP_022962362	topoisomerase I [Pseudomonas pelagia].	21.79	537	342	17	7	505	6	502	2e-11	77.4
rs:WP_022864544	DNA topoisomerase I [Varibaculum cambriense].	23.19	565	326	20	1	505	1	517	2e-11	77.4
rs:WP_035490613	DNA topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	2e-11	77.4
rs:WP_039316996	DNA topoisomerase I [Clostridium baratii].	24.28	523	322	21	7	505	6	478	2e-11	77.4
rs:WP_035400416	DNA topoisomerase I [Faecalitalea cylindroides].	24.67	527	312	19	7	505	6	475	2e-11	77.4
tr:B2KBN6_ELUMP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.82	564	310	25	7	510	21	530	2e-11	77.4
rs:WP_039775658	DNA topoisomerase I [Nocardia cerradoensis].	23.31	592	352	21	7	550	5	542	2e-11	77.4
rs:WP_021321700	DNA topoisomerase I [Geobacillus sp. A8].	22.95	623	380	22	7	598	6	559	2e-11	77.4
rs:WP_019191838	DNA topoisomerase I [Anaerococcus pacaensis].	24.01	608	346	27	7	580	6	531	2e-11	77.4
rs:WP_035496414	DNA topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	2e-11	77.4
tr:S4E3P0_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EPI11975.1};	29.67	182	113	5	5	178	3	177	2e-11	73.6
rs:WP_036885046	hypothetical protein, partial [Prevotella disiens].	25.82	213	135	6	331	531	1	202	2e-11	76.3
rs:WP_013214669	DNA topoisomerase I [Hyphomicrobium denitrificans].	25.15	493	268	18	80	505	46	504	2e-11	77.4
rs:WP_030925183	DNA topoisomerase I [Streptomyces sp. NRRL B-24720].	23.08	559	324	22	7	505	15	527	2e-11	77.4
rs:WP_016198248	DNA topoisomerase I [Elizabethkingia meningoseptica].	22.26	521	319	19	7	504	6	463	2e-11	77.4
rs:WP_009621355	DNA topoisomerase I [Pseudomonas sp. M1].	24.51	461	285	16	99	541	103	518	2e-11	77.4
rs:WP_023783252	DNA topoisomerase I [Mesorhizobium sp. LNHC220B00].	24.50	547	313	24	4	505	1	492	2e-11	77.4
rs:WP_002295589	MULTISPECIES: topoisomerase [Enterococcus].	38.98	118	62	5	5	118	3	114	2e-11	72.4
rs:WP_016975262	topoisomerase I [Pseudomonas fluorescens].	22.22	459	307	14	69	505	75	505	2e-11	77.4
rs:WP_045298032	DNA topoisomerase I [Microbacterium trichothecenolyticum].	22.66	587	355	20	7	550	8	538	2e-11	77.4
rs:WP_016324077	DNA topoisomerase I [Oscillibacter sp. 1-3].	21.87	535	338	18	1	505	1	485	2e-11	77.4
rs:WP_024164310	DNA topoisomerase I [Rhizobium sp. CF080].	24.50	551	311	27	4	505	1	495	2e-11	77.4
rs:WP_013166327	DNA topoisomerase I [Starkeya novella].	23.08	559	322	22	4	510	1	503	2e-11	77.4
rs:WP_044471025	DNA topoisomerase I [Mannheimia sp. MG13].	24.32	444	278	16	88	505	93	504	2e-11	77.4
rs:WP_010143115	DNA topoisomerase I [Citricoccus sp. CH26A].	23.27	550	335	18	7	505	11	524	2e-11	77.4
rs:WP_023770068	MULTISPECIES: DNA topoisomerase I [Mesorhizobium].	23.89	540	325	21	4	505	1	492	2e-11	77.4
tr:S9R5V8_9RHOB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	22.77	505	294	20	4	472	1	445	2e-11	76.6
rs:WP_007994702	topoisomerase I [Pseudomonas sp. GM49].	22.95	427	284	14	99	505	104	505	2e-11	77.4
rs:WP_005390799	DNA topoisomerase I [Corynebacterium glucuronolyticum].	25.45	440	270	15	107	505	91	513	2e-11	77.4
rs:WP_006359050	DNA topoisomerase I [Gordonia alkanivorans].	22.91	550	336	18	7	505	18	530	2e-11	77.4
tr:A0A051TNA3_MYCTX	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.36	468	287	17	86	504	65	514	2e-11	77.4
rs:WP_043098176	DNA topoisomerase I, partial [bacterium JKG1].	23.57	543	320	20	7	504	6	498	2e-11	77.4
rs:WP_043868917	DNA topoisomerase I [Celeribacter indicus].	23.78	555	315	23	4	505	1	500	2e-11	77.4
rs:WP_011933781	DNA topoisomerase I [Synechococcus sp. WH 7803].	23.96	626	350	24	5	583	4	550	2e-11	77.4
rs:WP_011986801	DNA topoisomerase I [Clostridium botulinum].	24.18	546	327	21	7	517	10	503	2e-11	77.0
tr:A0A087F896_9PSED	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.30	538	339	21	7	505	6	503	2e-11	77.4
tr:K2CQ65_9BACT	RecName: Full=DNA topoisomerase I, plasmid {ECO:0000256|SAAS:SAAS00003555}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	23.33	630	366	25	7	593	5	560	2e-11	77.4
rs:WP_036432809	DNA topoisomerase I [Mycoplasma hominis].	21.08	517	332	16	7	504	6	465	2e-11	77.0
rs:WP_016408454	DNA topoisomerase [Firmicutes bacterium CAG:102].	24.19	525	321	22	7	505	33	506	2e-11	77.4
rs:WP_010733593	MULTISPECIES: hypothetical protein [Enterococcus].	38.98	118	62	5	5	118	3	114	2e-11	72.4
rs:WP_016279166	DNA topoisomerase I [Lachnospiraceae bacterium A4].	24.09	440	285	17	93	504	63	481	2e-11	77.0
rs:WP_046269261	DNA topoisomerase I [Pseudomonas syringae].	22.81	456	308	13	69	505	75	505	2e-11	77.4
rs:WP_003417673	topoisomerase I [Pseudomonas syringae].	22.81	456	308	13	69	505	75	505	2e-11	77.4
rs:WP_034156438	DNA topoisomerase I [Pseudomonas fluorescens].	23.09	459	303	16	69	505	75	505	2e-11	77.4
rs:WP_013257954	DNA topoisomerase I [Desulfarculus baarsii].	24.26	540	317	19	7	505	6	494	2e-11	77.4
rs:WP_043615263	DNA topoisomerase I [Nonomuraea candida].	23.47	554	325	23	7	505	1	510	2e-11	77.4
rs:WP_018352275	hypothetical protein [Longispora albida].	23.56	556	336	18	7	510	6	524	2e-11	77.4
rs:WP_005659512	topoisomerase I [Haemophilus influenzae].	24.12	452	289	18	79	505	82	504	2e-11	77.4
rs:WP_032823520	DNA topoisomerase I [Haemophilus influenzae].	23.13	549	330	23	3	505	2	504	2e-11	77.4
rs:WP_030561185	DNA topoisomerase I [Streptomyces aureocirculatus].	23.04	560	321	22	7	505	15	525	2e-11	77.4
rs:WP_038651466	DNA topoisomerase I [Prochlorococcus sp. MIT 0801].	23.01	552	326	19	5	505	6	509	2e-11	77.4
rs:WP_044286837	DNA topoisomerase I [Pseudomonas fluorescens].	22.22	459	307	14	69	505	75	505	2e-11	77.4
rs:WP_024641788	DNA topoisomerase I [Pseudomonas syringae].	22.81	456	308	13	69	505	75	505	2e-11	77.4
rs:WP_041477349	DNA topoisomerase I [Pseudomonas sp. PTA1].	23.09	459	303	16	69	505	75	505	2e-11	77.4
tr:I9YBT9_HELPX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	28.84	215	129	7	308	505	14	221	2e-11	76.6
rs:WP_003462075	topoisomerase I [Pseudomonas pseudoalcaligenes].	22.30	538	339	21	7	505	6	503	2e-11	77.4
rs:WP_003427121	DNA topoisomerase I subunit omega [Pseudomonas syringae].	22.93	458	305	14	69	505	75	505	2e-11	77.4
tr:J4SHF3_9MYCO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.36	468	287	17	86	504	65	514	2e-11	77.4
rs:WP_010212072	MULTISPECIES: topoisomerase I [Pseudomonas].	22.22	459	307	14	69	505	75	505	2e-11	77.4
rs:WP_015374403	MULTISPECIES: DNA topoisomerase I [Geobacillus].	22.95	623	380	22	7	598	6	559	2e-11	77.0
rs:WP_010430824	topoisomerase I [Pseudomonas syringae].	22.59	456	309	13	69	505	75	505	2e-11	77.4
rs:WP_036056444	DNA topoisomerase I [Leptotrichia goodfellowii].	23.86	528	310	20	7	504	6	471	2e-11	77.4
rs:WP_008616602	DNA topoisomerase I subunit omega [Magnetospirillum sp. SO-1].	24.68	539	318	24	4	504	1	489	2e-11	77.4
rs:WP_026320092	DNA topoisomerase I [Bacteroides barnesiae].	22.80	601	366	24	7	570	6	545	2e-11	77.4
rs:WP_038585743	DNA topoisomerase I [Neorhizobium galegae].	23.91	548	318	24	4	505	1	495	2e-11	77.4
rs:WP_046600125	DNA topoisomerase I [Neorhizobium galegae].	23.91	548	318	24	4	505	1	495	2e-11	77.4
rs:WP_022097363	DNA topoisomerase [Eubacterium eligens CAG:72].	24.91	538	301	27	7	504	6	480	2e-11	77.0
rs:WP_028906033	DNA topoisomerase I [Prevotella intermedia].	23.72	527	315	18	7	504	6	474	2e-11	77.4
rs:WP_008624637	toprim domain protein, partial [Paraprevotella xylaniphila].	28.70	223	137	7	6	220	3	211	2e-11	73.9
rs:WP_022789185	DNA topoisomerase I [[Streptococcus] pleomorphus].	24.14	526	316	18	7	505	6	475	2e-11	77.0
rs:WP_020800560	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	22.95	427	284	14	99	505	104	505	2e-11	77.4
rs:WP_040630636	DNA topoisomerase I [Mycobacterium colombiense].	24.36	468	287	17	86	504	85	534	2e-11	77.4
rs:WP_027036790	DNA topoisomerase I [Mesorhizobium ciceri].	24.07	540	324	22	4	505	1	492	2e-11	77.4
rs:WP_042037111	DNA topoisomerase III, partial [Escherichia coli].	28.57	210	137	7	8	214	5	204	2e-11	73.9
rs:WP_030718342	DNA topoisomerase I [Streptomyces griseus].	23.08	559	324	21	7	505	15	527	2e-11	77.4
tr:A0A0D6N3W7_9PROT	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:GAN60243.1};	24.77	549	319	23	7	510	5	504	2e-11	77.4
rs:WP_018917300	topoisomerase I [Halomonas zhanjiangensis].	22.64	455	309	13	69	505	80	509	2e-11	77.4
rs:WP_045725701	DNA topoisomerase I [Clostridium baratii].	24.09	523	323	21	7	505	6	478	2e-11	77.0
rs:WP_027395008	DNA topoisomerase I [Aquimarina latercula].	25.90	525	297	23	7	505	6	464	2e-11	77.4
rs:WP_004470045	DNA topoisomerase I [Leptospira santarosai].	23.43	525	320	19	5	505	3	469	2e-11	77.0
rs:WP_030342291	DNA topoisomerase I [Streptomyces floridae].	23.08	559	324	22	7	505	15	527	2e-11	77.4
tr:D6KHW4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.67	527	314	24	7	504	32	504	2e-11	77.0
rs:WP_035282705	hypothetical protein, partial [Brevibacterium album].	23.68	570	325	20	7	505	12	542	2e-11	77.4
rs:WP_012912458	DNA topoisomerase I [Pirellula staleyi].	23.29	614	359	25	7	579	13	555	2e-11	77.4
rs:WP_007264936	DNA topoisomerase I [Streptomyces sp. C].	23.21	560	319	22	7	505	15	524	2e-11	77.4
rs:WP_039139011	DNA topoisomerase I [Gallibacterium anatis].	23.36	441	286	16	88	505	93	504	2e-11	77.4
rs:WP_022331603	DNA topoisomerase [Firmicutes bacterium CAG:345].	23.77	530	329	22	97	599	68	549	2e-11	77.0
rs:WP_004479531	DNA topoisomerase I [Leptospira santarosai].	23.24	525	321	19	5	505	3	469	2e-11	77.0
tr:D4IVN0_BUTFI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.19	496	304	23	47	504	21	482	2e-11	77.0
tr:T1B5Z5_9ZZZZ	SubName: Full=DNA topoisomerase III beta {ECO:0000313|EMBL:EQD65427.1}; Flags: Fragment;	26.36	239	153	6	102	334	98	319	2e-11	75.1
rs:WP_035374814	DNA topoisomerase I, partial [Acetobacter persici].	24.55	554	314	26	7	510	5	504	2e-11	77.4
rs:WP_030764024	DNA topoisomerase I [Streptomyces sp. NRRL F-2664].	23.43	559	319	23	7	505	15	524	2e-11	77.4
rs:WP_011715198	DNA topoisomerase I [Magnetococcus marinus].	24.91	554	313	24	7	505	5	510	3e-11	77.0
rs:WP_008050053	topoisomerase I [Pseudomonas sp. GM74].	22.95	427	284	14	99	505	104	505	3e-11	77.4
rs:WP_038542035	DNA topoisomerase I [Neorhizobium galegae].	23.91	548	318	24	4	505	1	495	3e-11	77.4
rs:WP_022744691	DNA topoisomerase 1 [Clostridium saccharobutylicum].	25.00	528	313	22	7	505	6	479	3e-11	77.0
rs:WP_012047858	DNA topoisomerase I [Clostridium botulinum].	24.18	546	327	21	7	517	6	499	3e-11	77.0
gp:CP005384_1002	DNA topoisomerase I subunit omega [Haemophilus parasuis ZJ0906]	23.57	454	288	18	79	505	27	448	3e-11	77.0
rs:WP_022361564	GTP-sensing transcriptional pleiotropic repressor CodY [Bacteroides pectinophilus CAG:437].	24.04	441	284	16	93	504	63	481	3e-11	77.0
tr:A4NYH0_HAEIF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.50	549	328	23	3	505	2	504	3e-11	77.0
rs:WP_042601494	DNA topoisomerase I [Haemophilus influenzae].	23.50	549	328	23	3	505	2	504	3e-11	77.0
rs:WP_026950130	DNA topoisomerase I [Algoriphagus mannitolivorans].	22.93	519	323	16	7	505	6	467	3e-11	77.0
rs:WP_046624251	DNA topoisomerase I [Neorhizobium galegae].	23.91	548	318	24	4	505	1	495	3e-11	77.0
tr:I1QQ61_ORYGL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.08	533	337	19	1	498	1	495	3e-11	77.0
rs:WP_044374707	DNA topoisomerase I [Streptomyces griseus].	23.08	559	324	21	7	505	15	527	3e-11	77.4
rs:WP_030813093	DNA topoisomerase I [Streptomyces mediolani].	23.08	559	324	21	7	505	15	527	3e-11	77.4
tr:J1JDU2_BARDO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.94	453	270	19	97	504	81	508	3e-11	77.0
rs:WP_029635180	DNA topoisomerase I [[Scytonema hofmanni] UTEX B 1581].	23.59	513	307	14	89	566	72	534	3e-11	77.0
rs:XP_006572652	PREDICTED: uncharacterized protein LOC102654326, partial [Apis mellifera].	26.07	399	242	14	116	489	1	371	3e-11	75.9
rs:WP_012616618	DNA topoisomerase I [Chloroflexus aggregans].	22.34	555	338	18	7	514	6	514	3e-11	77.0
rs:WP_004280500	DNA topoisomerase I [Leptospira borgpetersenii].	23.15	527	323	18	1	504	1	468	3e-11	76.6
rs:WP_011272639	topoisomerase I [Haemophilus influenzae].	23.13	549	330	23	3	505	2	504	3e-11	77.0
gpu:CP009501_74	DNA topoisomerase I [Methanosarcina thermophila TM-1]	23.46	567	359	19	8	548	6	523	3e-11	77.0
rs:WP_005064939	DNA topoisomerase I [Mycobacterium abscessus].	24.63	475	281	15	86	504	69	522	3e-11	77.0
rs:WP_002549474	DNA topoisomerase I [Propionibacterium acnes].	24.09	469	284	18	86	505	72	517	3e-11	77.0
rs:WP_042831491	DNA topoisomerase I [Streptomyces rimosus].	25.32	466	262	20	97	505	91	527	3e-11	77.0
rs:WP_002840064	toprim domain protein, partial [Finegoldia magna].	26.09	230	148	7	7	232	4	215	3e-11	73.9
rs:WP_036882691	DNA topoisomerase I [Prevotella disiens].	25.58	430	258	14	7	430	25	398	3e-11	77.0
tr:B0RAE2_CLAMS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.20	554	333	18	7	505	50	560	3e-11	77.4
tr:J9CX79_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJX04866.1};	23.89	519	315	21	9	504	1	462	3e-11	77.0
rs:WP_005687215	topoisomerase I [Haemophilus influenzae].	23.50	549	328	23	3	505	2	504	3e-11	77.0
tr:M1ZP81_CLOBO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKN40186.1}; Flags: Fragment;	28.19	188	118	4	72	253	1	177	3e-11	73.2
rs:WP_039791863	DNA topoisomerase III, partial [Haemophilus sputorum].	24.92	309	211	8	65	364	5	301	3e-11	74.7
rs:WP_003403702	topoisomerase I [Pseudomonas syringae].	22.81	456	308	13	69	505	75	505	3e-11	77.0
rs:XP_006450082	hypothetical protein CICLE_v10007345mg [Citrus clementina].	25.14	521	296	22	47	505	194	682	3e-11	77.0
rs:WP_024499534	DNA topoisomerase I [Gordonia amicalis].	23.03	547	339	18	7	505	18	530	3e-11	77.4
rs:WP_046041393	DNA topoisomerase I [Pseudomonas fluorescens].	22.95	427	284	14	99	505	104	505	3e-11	77.0
rs:WP_018604863	DNA topoisomerase I [Pseudomonas sp. CFII68].	21.93	456	312	13	69	505	75	505	3e-11	77.0
tr:G9QFT8_9BACI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHL65059.1};	33.56	149	87	6	7	149	5	147	3e-11	72.8
rs:WP_021035179	DNA topoisomerase I [Haemophilus influenzae].	22.89	546	335	22	3	505	2	504	3e-11	77.0
rs:WP_035953383	DNA topoisomerase I [Frankia sp. EUN1f].	23.57	560	323	21	7	505	41	556	3e-11	77.0
rs:WP_008082212	topoisomerase I [Pseudomonas sp. GM80].	23.09	459	303	16	69	505	75	505	3e-11	77.0
rs:WP_025212749	DNA topoisomerase I [Pseudomonas brassicacearum].	21.93	456	312	13	69	505	75	505	3e-11	77.0
gpu:CP009517_2395	DNA topoisomerase I [Methanosarcina barkeri 3]	24.28	523	328	21	8	498	6	492	3e-11	77.0
rs:WP_004474620	DNA topoisomerase I [Leptospira santarosai].	22.94	523	325	18	5	505	3	469	3e-11	76.6
rs:WP_015477970	DNA topoisomerase I subunit omega [Pseudomonas denitrificans].	24.73	461	284	17	99	541	102	517	3e-11	77.0
rs:WP_031307068	DNA topoisomerase I [Brachybacterium muris].	22.95	549	333	21	7	505	8	516	3e-11	77.0
rs:XP_004233765	PREDICTED: uncharacterized protein LOC101248941 isoform X2 [Solanum lycopersicum].	24.71	518	301	21	47	505	383	870	3e-11	77.4
rs:WP_028619418	DNA topoisomerase I [Pseudomonas sp. 2-92(2010)].	22.22	459	307	14	69	505	75	505	3e-11	77.0
rs:WP_046944484	DNA topoisomerase I [Leptospira santarosai].	22.94	523	325	18	5	505	3	469	3e-11	76.6
rs:WP_019614490	topoisomerase I [Psychromonas ossibalaenae].	23.33	553	354	22	69	598	76	581	3e-11	77.0
rs:WP_014852237	topoisomerase I [Pseudomonas stutzeri].	22.88	437	293	14	88	505	91	502	3e-11	77.0
rs:WP_004465158	DNA topoisomerase I [Leptospira santarosai].	22.94	523	325	18	5	505	3	469	3e-11	76.6
rs:WP_046819513	DNA topoisomerase I [Pseudomonas putida].	22.95	427	284	14	99	505	104	505	3e-11	77.0
rs:WP_044487619	DNA topoisomerase I [Mycobacterium tuberculosis].	24.36	468	287	17	86	504	85	534	3e-11	77.0
rs:WP_018489446	DNA topoisomerase I [Streptomyces sp. CcalMP-8W].	22.50	560	326	22	7	505	15	527	3e-11	77.0
rs:WP_005732652	MULTISPECIES: topoisomerase I [Pseudomonas syringae group genomosp. 2].	22.83	530	348	17	7	505	6	505	3e-11	77.0
rs:WP_021113464	DNA topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	3e-11	77.0
rs:WP_033512642	DNA topoisomerase I, partial [Bifidobacterium mongoliense].	22.20	572	325	22	7	505	8	532	3e-11	77.0
rs:WP_024864222	DNA topoisomerase I [Bartonella doshiae].	24.94	453	270	19	97	504	65	492	3e-11	77.0
rs:WP_042594644	DNA topoisomerase I [Haemophilus influenzae].	23.13	549	330	23	3	505	2	504	3e-11	77.0
tr:A0A087C4P5_9BIFI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.20	572	325	22	7	505	8	532	3e-11	77.0
rs:WP_026300384	DNA topoisomerase I [Halomonas lutea].	21.58	533	356	16	7	505	6	510	3e-11	77.0
rs:WP_007341842	DNA topoisomerase I [Neisseria bacilliformis].	23.26	533	325	16	7	505	6	488	3e-11	77.0
tr:D4LWC7_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.22	531	323	21	7	504	6	479	3e-11	76.6
rs:WP_013164497	DNA topoisomerase I [Desulfurivibrio alkaliphilus].	24.13	547	313	22	7	505	6	498	3e-11	77.0
rs:WP_041076433	DNA topoisomerase I [Thermotoga caldifontis].	25.59	426	251	19	107	504	75	462	3e-11	77.0
tr:A0A096CWZ0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.46	432	256	14	7	430	6	379	3e-11	77.0
rs:WP_026916483	DNA topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	3e-11	77.0
rs:WP_004837938	hypothetical protein, partial [Anaerococcus tetradius].	32.26	155	91	5	266	417	4	147	3e-11	72.8
rs:WP_023491655	DNA topoisomerase 1 [Serratia sp. DD3].	26.35	444	248	21	99	505	97	498	3e-11	77.0
rs:WP_032782336	DNA topoisomerase I [Streptomyces sp. JS01].	23.08	559	324	21	7	505	15	527	3e-11	77.0
rs:WP_010785769	DNA topoisomerase I subunit omega [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	3e-11	77.0
rs:WP_012832491	DNA topoisomerase I [Gordonia bronchialis].	22.71	546	342	18	7	505	19	531	3e-11	77.0
rs:WP_029608746	DNA topoisomerase I [Mycoplasma simbae].	24.81	524	310	23	7	504	5	470	3e-11	76.6
rs:WP_018206960	DNA topoisomerase I [actinobacterium SCGC AAA024-D14].	23.76	564	330	24	4	510	9	529	3e-11	77.0
rs:WP_003931741	DNA topoisomerase I [Mycobacterium vaccae].	23.94	472	285	17	86	504	91	541	3e-11	77.0
rs:WP_009181788	DNA topoisomerase I [Desulfovibrio sp. FW1012B].	25.00	440	289	14	88	505	58	478	3e-11	77.0
rs:WP_041900725	hypothetical protein, partial [Marinimicrobia bacterium SCGC AAA160-B08].	24.39	537	318	21	7	504	9	496	3e-11	77.0
rs:WP_016780049	topoisomerase I [Pseudomonas fragi].	23.86	461	297	17	69	505	75	505	3e-11	77.0
rs:WP_037587770	DNA topoisomerase I [Staphylococcus aureus].	24.35	538	303	22	7	504	6	479	3e-11	76.6
rs:WP_005656771	topoisomerase I [Haemophilus influenzae].	24.34	452	288	18	79	505	82	504	3e-11	77.0
rs:WP_039634246	DNA topoisomerase I [Streptomyces sp. 769].	25.65	460	268	19	97	505	91	527	3e-11	77.0
rs:WP_022104140	DNA topoisomerase [Bacteroides stercoris CAG:120].	23.75	522	316	18	7	504	6	469	3e-11	77.0
rs:WP_031325380	DNA topoisomerase III, partial [Pseudomonas taiwanensis].	45.45	88	46	1	461	548	5	90	3e-11	73.2
rs:WP_002233406	DNA topoisomerase I [Neisseria meningitidis].	24.44	532	320	19	7	505	6	488	3e-11	77.0
sp:TOP1_FERIS	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	25.34	596	339	25	7	583	41	549	3e-11	76.6
rs:WP_005666969	topoisomerase I [Haemophilus influenzae].	23.13	549	330	23	3	505	2	504	3e-11	77.0
rs:WP_042150501	DNA topoisomerase I [Streptomyces sp. NBRC 110027].	24.62	459	273	18	97	505	91	526	3e-11	77.0
rs:WP_011770299	topoisomerase I [Psychromonas ingrahamii].	23.59	462	295	17	69	504	76	505	3e-11	77.0
rs:XP_010316521	PREDICTED: uncharacterized protein LOC101248941 isoform X1 [Solanum lycopersicum].	24.71	518	301	21	47	505	385	872	3e-11	77.0
rs:WP_036456737	DNA topoisomerase I [Mycobacterium marinum].	24.52	469	287	17	86	505	88	538	3e-11	77.0
rs:WP_014974405	DNA topoisomerase I [Leuconostoc carnosum].	23.82	529	315	21	7	504	31	502	3e-11	76.6
rs:WP_004843019	DNA topoisomerase I [[Ruminococcus] gnavus].	23.48	528	322	22	7	504	6	481	3e-11	76.6
rs:WP_014323368	DNA topoisomerase I [Desulfovibrio desulfuricans].	23.65	537	313	19	7	505	6	483	3e-11	77.0
rs:WP_030599765	DNA topoisomerase I [Streptomyces fulvoviolaceus].	22.94	558	324	23	7	505	15	525	3e-11	77.0
rs:WP_030749301	DNA topoisomerase I [Streptomyces griseus].	23.16	557	324	22	7	505	15	525	3e-11	77.0
rs:WP_007592026	DNA topoisomerase I [Lachnoanaerobaculum sp. OBRC5-5].	25.51	439	273	16	97	504	67	482	3e-11	76.6
rs:WP_015266922	DNA topoisomerase I [Echinicola vietnamensis].	23.14	523	317	19	7	505	6	467	3e-11	76.6
rs:WP_009500471	topoisomerase I [Haemophilus sp. oral taxon 851].	23.18	548	331	22	3	505	2	504	3e-11	77.0
rs:WP_004462295	DNA topoisomerase I [Leptospira santarosai].	22.94	523	325	18	5	505	3	469	3e-11	76.6
rs:WP_029369302	DNA topoisomerase I [Mycobacterium sp. UM_WWY].	24.31	510	304	18	86	550	85	557	3e-11	77.0
rs:WP_039919895	DNA topoisomerase I, partial [Leptotrichia goodfellowii].	23.86	528	310	20	7	504	6	471	3e-11	76.6
rs:WP_012396656	DNA topoisomerase I [Mycobacterium marinum].	24.52	469	287	17	86	505	88	538	3e-11	77.0
rs:WP_011268332	DNA topoisomerase I [Pseudomonas syringae].	22.81	456	308	13	69	505	75	505	3e-11	77.0
rs:WP_004498175	DNA topoisomerase I [Leptospira weilii].	22.86	525	321	18	5	504	4	469	3e-11	76.6
rs:WP_020726831	DNA topoisomerase I [Mycobacterium marinum].	24.52	469	287	17	86	505	88	538	3e-11	77.0
tr:F9GJ95_HAEHA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.32	549	329	23	3	505	8	510	3e-11	77.0
rs:WP_034147900	DNA topoisomerase I [Pseudomonas fluorescens].	22.95	427	284	14	99	505	104	505	3e-11	77.0
rs:WP_016297112	DNA topoisomerase I [Lachnospiraceae bacterium M18-1].	23.04	447	281	19	93	504	63	481	3e-11	76.6
rs:WP_032825615	DNA topoisomerase I [Haemophilus haemolyticus].	23.68	549	327	23	3	505	2	504	3e-11	77.0
rs:WP_013380804	DNA topoisomerase I [Eubacterium limosum].	24.48	433	284	13	97	504	67	481	3e-11	76.6
rs:WP_007174734	DNA topoisomerase I [Prevotella bergensis].	23.51	570	335	24	7	543	6	507	3e-11	76.6
rs:WP_029957349	hypothetical protein, partial [Acetothermia bacterium SCGC AAA255-C06].	22.98	531	319	20	7	504	7	480	3e-11	76.6
rs:WP_037369212	DNA topoisomerase I [Amycolatopsis orientalis].	23.42	555	328	20	7	505	22	535	3e-11	77.0
rs:WP_028416080	DNA topoisomerase I [Streptomyces sp. SolWspMP-sol2th].	22.86	560	324	22	7	505	15	527	3e-11	77.0
rs:WP_026222843	DNA topoisomerase I [Methylocystis rosea].	23.92	556	320	24	4	510	1	502	3e-11	77.0
rs:WP_015750544	DNA topoisomerase I [Desulfohalobium retbaense].	23.65	444	282	16	93	506	63	479	3e-11	76.6
rs:WP_046953148	DNA topoisomerase I [Haemophilus haemolyticus].	23.68	549	327	23	3	505	2	504	3e-11	76.6
rs:WP_032583404	DNA topoisomerase I, partial [Bacteroides fragilis].	27.84	255	161	9	309	550	1	245	3e-11	75.5
tr:E6QPP2_9ZZZZ	SubName: Full=DNA topoisomerase 1 (DNA topoisomerase I) (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) {ECO:0000313|EMBL:CBI09213.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CBI09213.1};	25.40	441	260	16	107	504	77	491	3e-11	76.6
rs:WP_011526737	DNA topoisomerase I [Lawsonia intracellularis].	24.71	526	316	21	7	504	6	479	3e-11	76.6
rs:WP_003967422	DNA topoisomerase I [Streptomyces sp. ACT-1].	22.90	559	325	21	7	505	15	527	3e-11	77.0
rs:WP_011772762	DNA topoisomerase I [Borrelia turicatae].	22.50	600	355	24	7	561	7	541	3e-11	76.6
rs:WP_046073425	DNA topoisomerase I [Salinivibrio sp. KP-1].	24.24	462	293	18	69	505	74	503	3e-11	76.6
rs:WP_017955760	DNA topoisomerase I [actinobacterium SCGC AAA023-J06].	23.76	564	330	24	4	510	9	529	3e-11	77.0
rs:WP_035525139	DNA topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	3e-11	76.6
rs:WP_003183422	topoisomerase I [Pseudomonas fluorescens].	21.93	456	312	13	69	505	75	505	3e-11	76.6
rs:WP_038293838	DNA topoisomerase I, partial [alpha proteobacterium SCGC AB-629-F11].	23.97	534	328	20	4	504	1	489	3e-11	76.6
rs:WP_032654924	DNA topoisomerase I [Pseudomonas syringae].	22.81	456	308	13	69	505	75	505	3e-11	76.6
tr:A0A078SM90_9PORP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.40	545	322	21	9	525	1	483	3e-11	76.6
rs:WP_004493941	DNA topoisomerase I [Leptospira santarosai].	23.24	525	321	19	5	505	3	469	3e-11	76.3
rs:WP_004478055	DNA topoisomerase I [Leptospira santarosai].	23.14	523	324	18	5	505	3	469	3e-11	76.3
rs:WP_040715762	DNA topoisomerase I [Nocardia veterana].	23.61	593	349	22	7	550	5	542	3e-11	77.0
rs:WP_046839141	DNA topoisomerase I [Candidatus Synechococcus spongiarum].	25.90	444	269	14	101	505	85	507	3e-11	76.6
rs:WP_013525788	topoisomerase I [Haemophilus influenzae].	24.34	452	288	18	79	505	82	504	3e-11	76.6
rs:WP_017542879	DNA topoisomerase I [Nocardiopsis prasina].	23.26	546	339	19	7	505	26	538	3e-11	77.0
rs:WP_036425991	DNA topoisomerase I [Mycobacterium sp. 012931].	24.52	469	287	17	86	505	88	538	3e-11	76.6
rs:WP_022476334	DNA topoisomerase [Clostridium sp. CAG:273].	23.39	637	366	23	7	603	6	560	3e-11	76.6
tr:F8XZ68_STRAG	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EGS28193.1};	29.80	198	106	6	360	539	9	191	3e-11	73.9
rs:WP_012379792	DNA topoisomerase I [Streptomyces griseus].	22.90	559	325	21	7	505	15	527	3e-11	77.0
rs:WP_012621609	topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	3e-11	76.6
rs:WP_012509456	DNA topoisomerase I [Pelodictyon phaeoclathratiforme].	22.68	613	388	25	5	588	14	569	3e-11	76.6
rs:WP_024800961	DNA topoisomerase I [Nocardia sp. BMG51109].	23.13	601	344	22	7	550	24	563	4e-11	77.0
tr:C3V9X4_9PSED	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.73	461	284	17	99	541	102	517	4e-11	76.6
rs:WP_013545113	DNA topoisomerase I [Bartonella clarridgeiae].	25.33	458	264	20	97	505	65	493	4e-11	76.6
rs:WP_034459248	DNA topoisomerase I [Bartonella koehlerae].	24.04	549	312	25	4	504	1	492	4e-11	76.6
rs:WP_022930930	DNA topoisomerase I [Treponema bryantii].	24.44	532	312	23	5	504	10	483	4e-11	76.6
rs:WP_014021586	DNA topoisomerase I [Cyclobacterium marinum].	24.28	519	313	18	7	504	6	465	4e-11	76.6
rs:WP_004481537	DNA topoisomerase I [Leptospira santarosai].	22.94	523	325	18	5	505	3	469	4e-11	76.3
rs:WP_044658889	DNA topoisomerase I [Micrococcus sp. MS-ASIII-49].	23.09	563	329	22	7	505	19	541	4e-11	76.6
tr:B0NRM5_BACSE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.75	522	316	18	7	504	29	492	4e-11	76.6
rs:WP_025167376	DNA topoisomerase I [Pseudomonas taeanensis].	22.33	533	346	16	7	505	6	504	4e-11	76.6
rs:WP_039890612	DNA topoisomerase I [Mycobacterium xenopi].	24.21	508	306	19	86	550	82	553	4e-11	76.6
rs:WP_005637485	DNA topoisomerase I [Parabacteroides merdae].	24.62	520	311	20	7	504	6	466	4e-11	76.6
rs:WP_009708791	DNA topoisomerase I [Desmospora sp. 8437].	23.31	532	318	24	7	504	6	481	4e-11	76.6
rs:WP_006852033	DNA topoisomerase I [Synechococcus sp. WH 8109].	22.95	610	368	17	5	579	4	546	4e-11	76.6
rs:WP_013531916	DNA topoisomerase I [Mesorhizobium ciceri].	24.07	540	324	22	4	505	1	492	4e-11	76.6
rs:WP_016755266	DNA topoisomerase I [Leptospira santarosai].	23.22	521	322	18	7	505	5	469	4e-11	76.3
tr:D0GKB0_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.86	528	310	20	7	504	19	484	4e-11	76.6
rs:WP_024568243	DNA topoisomerase I [Elizabethkingia anophelis].	22.69	520	318	19	7	504	6	463	4e-11	76.6
rs:WP_039129205	DNA topoisomerase I [Flavihumibacter sp. ZG627].	22.75	523	324	19	7	505	6	472	4e-11	76.6
rs:WP_042560168	DNA topoisomerase I [Pseudomonas fluorescens].	23.31	459	302	16	69	505	75	505	4e-11	76.6
rs:WP_017863681	DNA topoisomerase I [Leptospira santarosai].	23.33	523	319	19	7	505	5	469	4e-11	76.3
rs:WP_039964959	DNA topoisomerase I [Veillonella sp. 6_1_27].	24.19	525	319	22	7	504	76	548	4e-11	76.6
rs:WP_022321949	DNA topoisomerase [Parabacteroides merdae CAG:48].	24.62	520	311	20	7	504	6	466	4e-11	76.6
rs:WP_036341214	DNA topoisomerase I [Micrococcus luteus].	23.09	563	329	22	7	505	19	541	4e-11	76.6
rs:WP_040316003	DNA topoisomerase I [Bacteroides stercoris].	23.75	522	316	18	7	504	6	469	4e-11	76.6
rs:WP_013527698	topoisomerase I [Haemophilus influenzae].	23.13	549	330	23	3	505	2	504	4e-11	76.6
tr:M1ZQM3_CLOBO	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKN41862.1}; Flags: Fragment;	28.40	169	108	3	72	238	1	158	4e-11	72.8
rs:WP_029353009	DNA topoisomerase I [Mesorhizobium ciceri].	25.23	551	304	25	4	505	1	492	4e-11	76.6
rs:WP_031819753	DNA topoisomerase I, partial [Vibrio parahaemolyticus].	24.34	419	270	16	107	505	1	392	4e-11	76.6
rs:WP_008688650	DNA topoisomerase I [Eubacterium sp. 3_1_31].	25.05	455	282	18	80	505	50	474	4e-11	76.6
rs:WP_047000611	DNA topoisomerase I [Clostridium beijerinckii].	23.90	523	325	18	7	505	6	479	4e-11	76.6
rs:WP_018704265	hypothetical protein [Anaeromusa acidaminophila].	22.91	633	386	23	5	606	4	565	4e-11	76.6
rs:WP_025993435	DNA topoisomerase I [Pseudomonas viridiflava].	22.93	458	305	14	69	505	75	505	4e-11	76.6
rs:WP_037281968	DNA topoisomerase I [Ruminococcus flavefaciens].	25.19	528	315	20	7	505	11	487	4e-11	76.6
rs:WP_033950115	DNA topoisomerase I [Pseudomonas aeruginosa].	22.20	563	347	17	7	541	6	505	4e-11	76.6
tr:E1KUI6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.87	433	253	16	7	430	20	393	4e-11	76.6
rs:WP_017169014	hypothetical protein, partial [Xanthomonas axonopodis].	28.34	187	117	4	376	548	25	208	4e-11	75.1
rs:WP_005647008	DNA topoisomerase I [Parabacteroides merdae].	24.62	520	311	20	7	504	6	466	4e-11	76.6
rs:WP_033268914	DNA topoisomerase I [Streptomyces lydicus].	24.84	459	272	18	97	505	91	526	4e-11	76.6
rs:WP_040063189	DNA topoisomerase I [Pseudomonas batumici].	22.15	456	311	13	69	505	75	505	4e-11	76.6
tr:K7T463_9NEIS	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.44	536	316	21	7	505	6	489	4e-11	75.9
rs:WP_043304444	DNA topoisomerase I [Pseudomonas viridiflava].	22.93	458	305	14	69	505	75	505	4e-11	76.6
rs:WP_003877079	DNA topoisomerase I [Mycobacterium avium].	24.36	468	287	17	86	504	85	534	4e-11	76.6
rs:WP_017168549	hypothetical protein, partial [Xanthomonas axonopodis].	28.34	187	117	4	376	548	23	206	4e-11	75.1
rs:WP_020073187	DNA topoisomerase I [[Clostridium] sporosphaeroides].	23.53	578	334	22	7	553	5	505	4e-11	76.3
rs:WP_017906684	topoisomerase I [Pseudomonas fuscovaginae].	23.19	427	283	14	99	505	104	505	4e-11	76.6
tr:A0A024FAL9_UREPR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.84	591	363	22	29	581	19	554	4e-11	76.3
rs:WP_032630415	DNA topoisomerase I [Pseudomonas syringae].	22.45	530	349	16	7	505	6	504	4e-11	76.6
rs:WP_040828386	DNA topoisomerase I [Nocardia jiangxiensis].	23.70	595	349	22	7	550	30	570	4e-11	76.6
tr:I0RMA2_MYCXE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.21	508	306	19	86	550	63	534	4e-11	76.6
tr:K2FS61_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.45	544	313	22	7	505	4	494	4e-11	76.6
rs:WP_022162924	DNA topoisomerase [Bacteroides sp. CAG:633].	23.84	558	341	21	7	539	6	504	4e-11	76.6
rs:WP_011679534	DNA topoisomerase I [Leuconostoc mesenteroides].	23.16	531	316	22	7	504	26	497	4e-11	76.3
rs:WP_004164241	DNA topoisomerase I [Leuconostoc mesenteroides].	23.16	531	316	22	7	504	26	497	4e-11	76.3
rs:WP_008057949	topoisomerase I [Pseudomonas sp. GM78].	22.95	427	284	14	99	505	104	505	4e-11	76.6
rs:WP_010056058	DNA topoisomerase I [Streptomyces globisporus].	23.08	559	324	21	7	505	15	527	4e-11	76.6
rs:WP_016574364	MULTISPECIES: DNA topoisomerase I [Streptomyces].	24.78	460	272	18	97	505	91	527	4e-11	76.6
rs:WP_038514169	DNA topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	4e-11	76.6
rs:WP_004883804	DNA topoisomerase I subunit omega [Pseudomonas viridiflava].	22.93	458	305	14	69	505	75	505	4e-11	76.6
tr:A0A067FLZ1_CITSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.14	525	291	24	47	505	87	575	4e-11	76.3
rs:WP_044362462	DNA topoisomerase I [Streptomyces natalensis].	24.13	460	275	18	97	505	91	527	4e-11	76.6
tr:D6KN24_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.19	525	319	22	7	504	32	504	4e-11	76.6
tr:K1V4E7_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78766.1}; Flags: Fragment;	28.14	199	127	5	43	239	12	196	4e-11	73.6
rs:WP_006689031	DNA topoisomerase I [Ureaplasma parvum].	22.84	591	363	22	29	581	15	550	4e-11	76.3
rs:WP_037319125	DNA topoisomerase I [Ruminobacter sp. RM87].	24.12	539	318	24	7	505	6	493	4e-11	76.6
rs:WP_024585500	DNA topoisomerase I [Aliihoeflea sp. 2WW].	23.19	552	316	24	4	505	1	494	4e-11	76.6
rs:WP_036086741	DNA topoisomerase I [Leptospira weilii].	22.94	523	319	18	7	504	5	468	4e-11	76.3
sp:TOP3B_ORYSJ	RecName: Full=DNA topoisomerase 3-beta; EC=5.99.1.2;	23.08	533	337	19	1	498	1	495	4e-11	76.6
rs:WP_026940978	DNA topoisomerase I [Hellea balneolensis].	24.50	547	307	25	7	505	4	492	4e-11	76.6
rs:WP_027937588	DNA topoisomerase I [Anaeroarcus burkinensis].	22.91	633	386	23	5	606	4	565	4e-11	76.3
rs:WP_017325221	hypothetical protein [Synechococcus sp. PCC 7336].	24.30	461	289	16	97	515	80	522	4e-11	76.6
rs:WP_028762074	DNA topoisomerase I [Shewanella colwelliana].	23.74	438	289	15	88	505	95	507	4e-11	76.6
rs:WP_021268964	DNA topoisomerase I [Mycobacterium abscessus].	24.21	475	283	15	86	504	69	522	4e-11	76.6
rs:WP_041639327	DNA topoisomerase III, partial [Anoxybacillus flavithermus].	29.89	174	99	5	375	546	38	190	4e-11	75.1
tr:A0A0B8P485_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM61590.1};	34.56	136	84	3	416	548	2	135	4e-11	73.2
rs:WP_002554104	topoisomerase I [Pseudomonas savastanoi].	22.59	456	309	13	69	505	75	505	4e-11	76.6
rs:WP_043584467	DNA topoisomerase I [Clavibacter michiganensis].	22.02	554	334	18	7	505	8	518	4e-11	76.6
rs:WP_045812520	DNA topoisomerase I [Rickettsia hoogstraalii].	23.63	546	327	21	7	510	4	501	4e-11	76.3
rs:WP_037029714	DNA topoisomerase I, partial [Psychrilyobacter atlanticus].	23.13	536	320	20	1	504	1	476	4e-11	76.3
rs:WP_044820000	DNA topoisomerase I [Bacteroides fragilis].	23.98	488	310	18	38	504	6	453	4e-11	76.3
rs:WP_009732875	DNA topoisomerase I [Anoxybacillus sp. DT3-1].	23.57	526	315	22	112	598	82	559	4e-11	76.3
rs:XP_001418460	predicted protein, partial [Ostreococcus lucimarinus CCE9901].	24.33	600	336	27	5	545	69	609	4e-11	76.6
rs:WP_004222574	hypothetical protein [Bifidobacterium pseudocatenulatum].	27.42	248	131	10	375	579	1	242	4e-11	75.1
rs:WP_005113110	MULTISPECIES: DNA topoisomerase I [Mycobacterium chelonae group].	24.21	475	283	15	86	504	69	522	4e-11	76.6
rs:WP_036090489	DNA topoisomerase I [Leuconostoc mesenteroides].	23.16	531	316	21	7	504	26	497	4e-11	76.3
rs:WP_012308141	DNA topoisomerase I [Synechococcus sp. PCC 7002].	24.35	542	331	19	5	505	3	506	4e-11	76.6
tr:M6VWD0_9LEPT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.24	525	321	19	5	505	3	469	4e-11	76.3
rs:WP_026753684	DNA topoisomerase I [Sediminibacter sp. Hel_I_10].	27.70	426	245	20	106	505	76	464	4e-11	76.6
rs:WP_017538191	MULTISPECIES: DNA topoisomerase I [Nocardiopsis].	22.92	554	330	22	7	505	26	537	4e-11	76.6
rs:WP_030189603	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.08	559	324	22	7	505	15	527	4e-11	76.6
rs:WP_030113344	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.08	559	324	22	7	505	15	527	4e-11	76.6
rs:WP_030724800	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.08	559	324	22	7	505	15	527	4e-11	76.6
rs:WP_029891836	DNA topoisomerase I [Mycoplasma columbinum].	25.20	500	319	18	97	564	68	544	4e-11	76.3
rs:WP_014730265	DNA topoisomerase I [Mesotoga prima].	24.76	521	314	20	7	504	6	471	4e-11	76.3
rs:WP_017939227	topoisomerase I [Pseudomonas thermotolerans].	22.20	536	340	17	7	505	6	501	4e-11	76.6
rs:WP_024351714	DNA topoisomerase I [Aurantimonas coralicida].	24.25	565	298	26	4	505	1	498	4e-11	76.6
rs:WP_026956978	DNA topoisomerase I [Algoriphagus vanfongensis].	23.25	529	308	18	7	505	6	466	4e-11	76.3
rs:WP_046314796	DNA topoisomerase I [Mycobacterium sp. UM_Kg1].	23.77	509	307	17	86	550	82	553	4e-11	76.6
rs:WP_046098886	DNA topoisomerase I [Avibacterium paragallinarum].	24.33	448	273	18	88	505	93	504	4e-11	76.6
rs:WP_030677717	DNA topoisomerase I [Streptomyces rimosus].	25.27	463	266	20	97	505	91	527	4e-11	76.6
tr:A0A067FIC2_CITSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.29	518	299	22	47	505	88	576	4e-11	75.9
rs:WP_034268541	DNA topoisomerase I [Amycolatopsis halophila].	22.78	553	336	20	7	505	22	537	4e-11	76.6
rs:WP_025370498	DNA topoisomerase I [Campylobacter fetus].	25.00	528	308	23	5	505	4	470	4e-11	76.3
tr:X7ZZN7_MYCAV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.73	469	284	17	86	504	65	514	4e-11	76.6
rs:WP_038534859	MULTISPECIES: DNA topoisomerase I [Mycobacterium avium complex (MAC)].	24.73	469	284	17	86	504	85	534	4e-11	76.6
rs:WP_027895073	DNA topoisomerase I [Megasphaera elsdenii].	22.66	534	323	22	7	504	59	538	4e-11	76.3
rs:WP_031295641	DNA topoisomerase I [Leuconostoc mesenteroides].	23.16	531	316	21	7	504	28	499	4e-11	76.3
rs:WP_043804823	DNA topoisomerase I, partial [Deinococcus gobiensis].	25.65	425	266	16	109	504	91	494	4e-11	75.9
rs:WP_045734776	DNA topoisomerase I, partial [Pseudomonas pseudoalcaligenes].	21.74	529	354	17	7	505	6	504	4e-11	76.3
rs:WP_003370501	topoisomerase I [Pseudomonas syringae].	22.81	456	308	13	69	505	75	505	4e-11	76.6
rs:WP_038655542	DNA topoisomerase I [Mucinivorans hirudinis].	23.27	520	317	20	7	505	4	462	4e-11	76.3
rs:WP_040556296	DNA topoisomerase I [Prevotella disiens].	25.87	433	253	16	7	430	25	398	4e-11	76.3
rs:WP_044912601	DNA topoisomerase I [Butyrivibrio sp. WCE2006].	24.10	444	282	19	93	505	66	485	4e-11	76.3
rs:WP_034442673	DNA topoisomerase I [Butyrivibrio sp. AE2032].	23.97	534	324	18	7	505	6	492	4e-11	76.3
rs:WP_019972782	DNA topoisomerase I [Mycobacterium sp. 141].	23.98	517	299	19	86	550	85	559	4e-11	76.6
rs:WP_014065398	topoisomerase I [Haemophilus parainfluenzae].	23.29	554	323	23	3	505	2	504	4e-11	76.3
rs:WP_029249170	DNA topoisomerase I [Mycobacterium avium].	23.58	509	308	17	86	550	82	553	4e-11	76.6
rs:WP_038441141	DNA topoisomerase I [Haemophilus influenzae].	23.13	549	330	23	3	505	2	504	4e-11	76.3
rs:WP_026835620	DNA topoisomerase I [Eubacterium xylanophilum].	22.54	457	301	15	81	505	45	480	4e-11	76.3
rs:WP_035495014	DNA topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	4e-11	76.3
tr:H8H1G5_DEIGI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.59	426	267	16	109	505	91	495	4e-11	76.3
rs:WP_014166394	DNA topoisomerase I [Flavobacterium columnare].	23.45	516	319	18	7	504	6	463	4e-11	76.3
rs:WP_018343699	DNA topoisomerase I [Cytophaga aurantiaca].	23.85	524	315	15	7	504	6	471	5e-11	76.3
rs:WP_029906193	DNA topoisomerase I [Prevotella sp. 10(H)].	25.17	600	337	26	7	564	6	535	5e-11	76.3
rs:WP_025020460	DNA topoisomerase I [Lactobacillus equi].	25.14	521	314	21	10	505	2	471	5e-11	76.3
rs:WP_027376008	DNA topoisomerase I [Chryseobacterium palustre].	23.21	530	303	24	7	504	6	463	5e-11	76.3
rs:WP_003436352	DNA topoisomerase I subunit omega [Pseudomonas syringae].	22.81	456	308	13	69	505	75	505	5e-11	76.3
rs:WP_007949671	topoisomerase I [Pseudomonas sp. GM24].	23.09	459	303	16	69	505	75	505	5e-11	76.3
rs:WP_038369385	DNA topoisomerase I [Pseudomonas chlororaphis].	23.09	459	303	16	69	505	75	505	5e-11	76.3
rs:WP_040005810	DNA topoisomerase I [Fibrisoma limi].	23.67	621	361	24	7	593	6	547	5e-11	76.3
rs:WP_022068892	DNA topoisomerase [Blautia sp. CAG:257].	23.16	531	318	22	7	504	6	479	5e-11	76.3
rs:WP_029241462	DNA topoisomerase I [Pseudomonas viridiflava].	22.93	458	305	14	69	505	75	505	5e-11	76.3
rs:WP_030591020	DNA topoisomerase I [Streptomyces globisporus].	22.90	559	325	21	7	505	15	527	5e-11	76.3
rs:WP_035685089	DNA topoisomerase I [Avibacterium paragallinarum].	24.33	448	273	18	88	505	93	504	5e-11	76.3
rs:WP_005662215	topoisomerase I [Haemophilus influenzae].	23.13	549	330	23	3	505	2	504	5e-11	76.3
rs:WP_005744458	topoisomerase I [Pseudomonas amygdali].	22.59	456	309	13	69	505	75	505	5e-11	76.3
rs:WP_034545244	DNA topoisomerase I [Clostridiales bacterium S7-1-4].	24.47	609	332	24	7	572	9	532	5e-11	76.3
rs:WP_024853033	DNA topoisomerase I [[Ruminococcus] gnavus].	23.48	528	322	22	7	504	6	481	5e-11	76.3
rs:WP_038439864	DNA topoisomerase I [Haemophilus influenzae].	23.13	549	330	23	3	505	2	504	5e-11	76.3
rs:WP_021347695	DNA topoisomerase I [Elizabethkingia meningoseptica].	22.69	520	318	19	7	504	6	463	5e-11	76.3
rs:WP_042910570	DNA topoisomerase I [Mycobacterium intracellulare].	24.73	469	284	17	86	504	85	534	5e-11	76.3
rs:WP_011962037	topoisomerase I [Haemophilus influenzae].	23.50	549	328	23	3	505	2	504	5e-11	76.3
rs:WP_023867727	DNA topoisomerase I [Mycobacterium avium].	24.36	468	287	17	86	504	85	534	5e-11	76.3
rs:WP_030334395	DNA topoisomerase I [Streptomyces sp. NRRL B-1381].	23.08	559	324	22	7	505	15	527	5e-11	76.3
rs:WP_014421722	topoisomerase I [Marinobacter hydrocarbonoclasticus].	23.53	425	285	15	99	505	108	510	5e-11	76.3
rs:WP_021109419	DNA topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	5e-11	76.3
rs:WP_039669897	DNA topoisomerase I [Coxiella endosymbiont of Amblyomma americanum].	25.50	498	299	19	86	536	57	529	5e-11	76.3
rs:WP_026161421	DNA topoisomerase I [Corynebacterium ciconiae].	25.27	455	271	19	103	505	90	527	5e-11	76.3
rs:WP_014383732	DNA topoisomerase I [Mycobacterium intracellulare].	24.73	469	284	17	86	504	85	534	5e-11	76.3
rs:WP_008263435	DNA topoisomerase I subunit omega [Mycobacterium sp. H4Y].	24.73	469	284	17	86	504	85	534	5e-11	76.3
rs:WP_024666109	DNA topoisomerase I [Pseudomonas syringae].	23.18	453	310	12	69	505	75	505	5e-11	76.3
rs:WP_042905719	DNA topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	5e-11	76.3
tr:M6ADH4_9LEPT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.94	523	319	18	7	504	6	469	5e-11	75.9
rs:WP_026990473	DNA topoisomerase I [Flavobacterium subsaxonicum].	24.42	520	309	22	7	504	6	463	5e-11	76.3
rs:WP_003708800	topoisomerase [Lactobacillus salivarius].	23.60	445	289	15	7	425	6	425	5e-11	76.3
tr:V2BSP1_SALDE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESH31240.1};	27.45	153	104	2	405	552	1	151	5e-11	73.2
rs:WP_005637796	topoisomerase I [Haemophilus haemolyticus].	23.50	549	328	23	3	505	2	504	5e-11	76.3
rs:WP_036059798	DNA topoisomerase I [Leptospira sp. P2653].	22.94	523	319	18	7	504	5	468	5e-11	75.9
rs:WP_021752225	DNA topoisomerase I [Gemella bergeri].	23.54	429	283	15	99	504	70	476	5e-11	75.9
rs:WP_040726675	DNA topoisomerase I [Thiomicrospira sp. Kp2].	23.84	537	293	23	7	504	5	464	5e-11	76.3
rs:WP_009086613	MULTISPECIES: DNA topoisomerase I [Elizabethkingia].	22.69	520	318	19	7	504	6	463	5e-11	76.3
rs:WP_003710938	topoisomerase [Lactobacillus salivarius].	23.15	445	291	14	7	425	6	425	5e-11	76.3
tr:Z2EWY0_VIBPH	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EVU20829.1}; Flags: Fragment;	29.35	184	114	6	8	184	6	180	5e-11	72.4
rs:WP_012534462	DNA topoisomerase [Aliivibrio fischeri].	22.45	597	364	22	7	539	3	564	5e-11	76.3
rs:WP_041691324	hypothetical protein, partial [Elusimicrobium minutum].	24.66	588	323	25	8	541	1	522	5e-11	76.3
rs:WP_046643722	DNA topoisomerase I [Turicella otitidis].	25.00	452	264	19	107	505	96	525	5e-11	76.3
rs:WP_010945247	topoisomerase I [Haemophilus ducreyi].	24.31	473	295	19	61	505	66	503	5e-11	76.3
rs:WP_044998816	hypothetical protein [Roseburia intestinalis].	31.18	170	107	5	7	174	4	165	5e-11	72.0
rs:WP_011520484	topoisomerase I [Candidatus Baumannia cicadellinicola].	22.62	526	336	23	7	505	6	487	5e-11	76.3
rs:WP_009162132	DNA topoisomerase I [Prevotella saccharolytica].	24.76	525	306	18	7	504	6	468	5e-11	76.3
rs:WP_016893440	DNA topoisomerase I [Mycobacterium abscessus].	24.42	475	282	15	86	504	69	522	5e-11	76.3
tr:A0A078T205_9PORP	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:KDS67260.1};	21.74	460	300	16	107	550	76	491	5e-11	75.9
rs:WP_020046071	DNA topoisomerase I [actinobacterium SCGC AAA027-M14].	23.50	549	328	21	7	505	14	520	5e-11	76.3
rs:WP_028692739	DNA topoisomerase I [Pseudomonas mosselii].	22.10	457	310	13	69	505	74	504	5e-11	76.3
rs:WP_019598710	DNA topoisomerase I [Rhodonellum psychrophilum].	23.65	520	316	19	7	504	6	466	5e-11	76.3
tr:A0A094QJY2_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KGA14741.1};	23.58	564	330	25	4	510	11	530	5e-11	76.3
rs:WP_030799698	DNA topoisomerase I [Streptomyces sp. NRRL F-3273].	23.08	559	324	22	7	505	15	527	5e-11	76.3
rs:WP_005817708	topoisomerase I [Actinobacillus minor].	24.32	444	277	19	88	505	94	504	5e-11	76.3
rs:WP_043265431	DNA topoisomerase I [Streptomyces sp. CT34].	24.62	459	273	18	97	505	91	526	5e-11	76.3
rs:WP_038556453	DNA topoisomerase I [Synechococcus sp. KORDI-52].	22.73	607	373	17	5	579	4	546	5e-11	76.3
tr:I2GJD4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.83	621	360	24	7	593	34	575	5e-11	76.3
rs:WP_046942317	DNA topoisomerase I [Haemophilus haemolyticus].	24.78	452	286	18	79	505	82	504	5e-11	76.3
rs:WP_004484542	DNA topoisomerase I [Leptospira santarosai].	22.75	523	326	18	5	505	3	469	5e-11	75.9
rs:WP_024051701	DNA topoisomerase, partial [Streptococcus anginosus].	33.06	124	79	3	376	496	32	154	5e-11	72.0
rs:WP_030597724	DNA topoisomerase I [Streptomyces rimosus].	25.27	463	266	20	97	505	91	527	5e-11	76.3
rs:WP_009137874	MULTISPECIES: DNA topoisomerase I [Odoribacter].	22.84	521	318	18	7	504	6	465	5e-11	76.3
rs:WP_023647218	DNA topoisomerase I [actinobacterium LLX17].	22.49	547	342	17	5	505	3	513	5e-11	76.3
rs:WP_034227298	DNA topoisomerase I [Actinotalea ferrariae].	23.49	464	290	16	7	442	8	434	5e-11	76.3
rs:WP_044313220	DNA topoisomerase I [Pseudomonas syringae].	23.14	458	304	14	69	505	75	505	5e-11	76.3
rs:WP_034869972	DNA topoisomerase I [Elizabethkingia miricola].	22.37	523	316	20	7	504	6	463	5e-11	76.3
rs:WP_014378962	DNA topoisomerase I [Mycobacterium intracellulare].	24.73	469	284	17	86	504	85	534	5e-11	76.3
rs:WP_026770357	DNA topoisomerase I [Sediminibacterium sp. OR53].	25.34	446	267	18	89	504	59	468	5e-11	76.3
tr:T0UGY1_LEUMC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.16	531	316	22	7	504	43	514	5e-11	75.9
rs:WP_034289746	DNA topoisomerase I [Amycolatopsis benzoatilytica].	23.33	553	331	20	7	505	22	535	5e-11	76.3
tr:W1W5N7_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.19	525	319	22	7	504	79	551	5e-11	76.3
rs:WP_022383953	DNA topoisomerase [Bacteroides sp. CAG:462].	23.54	616	370	23	7	584	6	558	5e-11	75.9
rs:WP_005377513	DNA topoisomerase I [Veillonella atypica].	23.79	580	349	23	7	564	69	577	5e-11	75.9
rs:WP_027161474	DNA topoisomerase I [Mesorhizobium sp. WSM1293].	24.07	540	324	22	4	505	1	492	5e-11	76.3
rs:WP_006924417	DNA topoisomerase I [Bartonella washoensis].	25.05	455	269	20	97	505	65	493	5e-11	76.3
rs:WP_047177953	DNA topoisomerase I [Streptomyces sp. MNU77].	23.04	560	323	22	7	505	15	527	6e-11	76.3
rs:WP_016891982	DNA topoisomerase I [Mycobacterium abscessus].	24.42	475	282	15	86	504	69	522	6e-11	76.3
rs:WP_021118106	DNA topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	6e-11	76.3
rs:WP_020272722	DNA topoisomerase 1 [Streptomyces afghaniensis].	23.84	558	319	24	7	505	15	525	6e-11	76.3
rs:XP_001386841	DNA topoisomerase [Scheffersomyces stipitis CBS 6054].	23.29	571	361	24	7	545	3	528	6e-11	75.9
tr:A0A017RZG0_9CLOT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.05	395	249	15	213	586	1	365	6e-11	75.5
rs:WP_016761066	DNA topoisomerase I [Leptospira weilii].	22.94	523	319	18	7	504	5	468	6e-11	75.9
rs:WP_014941198	DNA topoisomerase I [Mycobacterium indicus pranii].	24.73	469	284	17	86	504	85	534	6e-11	76.3
tr:C7G933_9FIRM	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EEV01684.1};	31.18	170	107	5	7	174	21	182	6e-11	72.4
rs:WP_025914261	DNA topoisomerase I [Prochlorococcus sp. scB245a_520K10].	26.07	445	267	17	101	505	85	507	6e-11	76.3
rs:WP_006996046	topoisomerase I [Haemophilus aegyptius].	23.23	551	327	24	3	505	2	504	6e-11	76.3
rs:WP_005102351	DNA topoisomerase I [Mycobacterium abscessus].	24.42	475	282	15	86	504	69	522	6e-11	76.3
rs:WP_042808036	DNA topoisomerase I [Streptomyces rimosus].	25.27	463	266	20	97	505	91	527	6e-11	76.3
rs:WP_028481868	DNA topoisomerase I [Nesiotobacter exalbescens].	25.00	556	314	23	4	510	1	502	6e-11	76.3
rs:WP_014710835	MULTISPECIES: DNA topoisomerase I [Mycobacterium].	24.73	469	284	17	86	504	85	534	6e-11	76.3
rs:WP_009955940	DNA topoisomerase I [Mycobacterium intracellulare].	24.73	469	284	17	86	504	85	534	6e-11	76.3
rs:WP_037012660	DNA topoisomerase I [Pseudomonas nitroreducens].	24.73	461	284	17	99	541	102	517	6e-11	76.3
rs:WP_024766855	DNA topoisomerase I [Pseudomonas nitroreducens].	24.73	461	284	17	99	541	102	517	6e-11	76.3
rs:WP_004571867	MULTISPECIES: DNA topoisomerase I [Streptomyces].	25.27	463	266	20	97	505	91	527	6e-11	76.3
rs:WP_030374829	MULTISPECIES: DNA topoisomerase I [Streptomyces].	25.27	463	266	20	97	505	91	527	6e-11	76.3
rs:WP_004601140	DNA topoisomerase I [Turicella otitidis].	25.00	452	264	19	107	505	96	525	6e-11	76.3
rs:WP_015205082	DNA topoisomerase I [Crinalium epipsammum].	22.30	538	347	14	5	505	3	506	6e-11	76.3
rs:WP_006334965	DNA topoisomerase 1 [Mesorhizobium sp. STM 4661].	24.13	543	320	22	4	505	1	492	6e-11	76.3
tr:I7BY88_PSEPT	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AFO49117.1};	45.45	88	46	1	461	548	9	94	6e-11	72.4
rs:WP_037069412	DNA topoisomerase I [Pseudonocardia acaciae].	22.83	552	340	17	7	505	46	564	6e-11	76.3
rs:WP_033237214	topoisomerase I [Rhodococcus rhodochrous].	26.03	461	249	22	7	425	6	416	6e-11	75.9
rs:WP_046713244	DNA topoisomerase I [Myxococcus fulvus].	23.27	477	293	16	93	516	141	597	6e-11	75.9
rs:WP_027113602	DNA topoisomerase I [Lachnospiraceae bacterium NK4A144].	23.68	532	321	25	7	504	6	486	6e-11	75.9
rs:WP_016887038	DNA topoisomerase I [Mycobacterium abscessus].	24.42	475	282	15	86	504	69	522	6e-11	76.3
rs:WP_026197617	DNA topoisomerase I [Sciscionella marina].	23.26	546	337	20	7	505	25	535	6e-11	76.3
rs:WP_039909173	DNA topoisomerase I [[Clostridium] scindens].	22.83	530	324	24	7	504	6	482	6e-11	75.9
rs:WP_030260198	DNA topoisomerase I [Streptomyces violens].	24.57	460	273	18	97	505	91	527	6e-11	76.3
rs:WP_005710869	topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	6e-11	75.9
rs:WP_044573128	DNA topoisomerase I [Streptomyces iranensis].	23.30	558	323	21	7	505	16	527	6e-11	76.3
rs:WP_026474023	DNA topoisomerase I [Alkaliflexus imshenetskii].	23.71	523	325	17	2	504	8	476	6e-11	75.9
rs:WP_007287285	DNA topoisomerase I [Intestinibacter bartlettii].	23.86	528	318	22	7	504	6	479	6e-11	75.9
rs:WP_017208335	DNA topoisomerase I [Mycobacterium abscessus].	24.42	475	282	15	86	504	69	522	6e-11	76.3
tr:T0SFG4_LACFE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.21	234	143	7	200	421	1	221	6e-11	72.8
rs:WP_032449797	DNA topoisomerase I [Brucella melitensis].	24.96	557	314	26	4	510	1	503	6e-11	75.9
rs:WP_016756882	DNA topoisomerase I [Leptospira santarosai].	23.14	523	324	18	5	505	3	469	6e-11	75.5
rs:WP_046364506	DNA topoisomerase I [Mycobacterium obuense].	23.83	470	288	15	86	504	82	532	6e-11	75.9
rs:WP_013253491	DNA topoisomerase I [Spirochaeta smaragdinae].	24.46	552	329	22	1	505	1	511	6e-11	75.9
rs:WP_038705745	DNA topoisomerase I [Pseudomonas mosselii].	22.10	457	310	13	69	505	74	504	6e-11	75.9
rs:XP_002503059	DNA topoisomerase I [Micromonas sp. RCC299].	22.85	652	368	28	7	581	137	730	6e-11	76.3
rs:WP_022230020	DNA topoisomerase [Firmicutes bacterium CAG:41].	23.54	378	236	12	198	553	14	360	6e-11	75.5
rs:WP_024689275	DNA topoisomerase I [Pseudomonas syringae].	22.59	456	309	13	69	505	75	505	6e-11	75.9
rs:WP_013767752	DNA topoisomerase I [Haliscomenobacter hydrossis].	24.74	570	321	22	7	550	6	493	6e-11	75.9
rs:XP_002772824	DNA topoisomerase 3-beta-1, putative [Perkinsus marinus ATCC 50983].	20.69	406	291	13	107	498	112	500	6e-11	75.9
rs:WP_036060849	DNA topoisomerase I [Leptospira weilii].	22.94	523	319	18	7	504	5	468	6e-11	75.5
rs:WP_030894263	DNA topoisomerase I [Streptomyces virginiae].	22.84	556	326	22	7	505	15	524	6e-11	75.9
rs:WP_019827482	DNA topoisomerase I [Pseudomonas sp. CF149].	23.43	461	299	16	69	505	75	505	6e-11	75.9
rs:WP_027611447	DNA topoisomerase I [Pseudomonas sp. URIL14HWK12:I6].	23.08	533	343	20	7	505	6	505	6e-11	75.9
rs:WP_012566718	DNA topoisomerase I [Rhodospirillum centenum].	23.95	547	320	21	1	505	1	493	6e-11	75.9
tr:A0A0D6BYJ6_9PSED	SubName: Full=DNA topoisomerase I subunit omega {ECO:0000313|EMBL:BAQ79945.1};	22.32	457	309	14	69	505	75	505	6e-11	75.9
rs:WP_021110589	DNA topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	6e-11	75.9
rs:WP_036906785	DNA topoisomerase I [Prochlorococcus marinus].	22.85	547	333	17	5	505	6	509	6e-11	75.9
rs:WP_032090097	DNA topoisomerase I [bacterium LF-3].	23.93	606	358	24	7	584	6	536	6e-11	75.9
rs:WP_043964776	DNA topoisomerase I [Anoxybacillus thermarum].	23.38	526	316	22	112	598	82	559	6e-11	75.9
tr:A0A090Q0M1_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.45	444	260	18	102	512	72	477	6e-11	75.9
rs:WP_035634529	DNA topoisomerase I [Lachnospiraceae bacterium ND2006].	24.06	453	273	20	93	504	63	485	6e-11	75.9
rs:WP_021817184	topoisomerase I [Halomonas sp. BJGMM-B45].	21.98	455	313	13	69	505	80	510	6e-11	75.9
rs:WP_017729828	hypothetical protein [Nafulsella turpanensis].	25.05	531	297	28	7	505	6	467	6e-11	75.9
rs:WP_042632765	DNA topoisomerase I [Mycobacterium avium].	24.36	468	287	16	86	504	85	534	6e-11	75.9
tr:D5DPQ9_BACMQ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ADE68980.1};	35.64	101	63	1	432	530	2	102	6e-11	73.6
rs:WP_005072605	DNA topoisomerase I [Mycobacterium abscessus].	24.42	475	282	15	86	504	69	522	6e-11	75.9
rs:WP_030942456	DNA topoisomerase I [Streptomyces sp. NRRL S-646].	23.06	555	327	22	7	505	15	525	7e-11	75.9
rs:WP_027691817	DNA topoisomerase I [Rathayibacter toxicus].	23.06	555	329	18	7	505	8	520	7e-11	75.9
rs:WP_012926623	DNA topoisomerase I [Spirosoma linguale].	24.08	436	258	14	7	431	6	379	7e-11	75.9
rs:WP_026773797	DNA topoisomerase I [Sediminibacterium sp. OR43].	25.79	442	272	18	89	505	59	469	7e-11	75.9
tr:M6Q9F4_9LEPT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.94	523	319	18	7	504	6	469	7e-11	75.5
rs:WP_019676957	topoisomerase I [Rheinheimera perlucida].	24.43	438	286	14	88	505	83	495	7e-11	75.9
rs:WP_044317786	DNA topoisomerase I [Pseudomonas amygdali].	22.59	456	309	13	69	505	75	505	7e-11	75.9
tr:B0N9B4_CLOSV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.83	530	324	23	7	504	20	496	7e-11	75.9
tr:W5T898_9NOCA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.48	592	351	21	7	550	35	572	7e-11	75.9
rs:WP_027841323	DNA topoisomerase I [Mastigocoleus testarum].	24.62	520	297	18	89	566	72	538	7e-11	75.9
rs:WP_005772953	DNA topoisomerase III, partial [Pseudomonas amygdali].	35.51	107	61	3	8	114	9	107	7e-11	70.5
rs:WP_024563609	DNA topoisomerase I [Wheat blue dwarf phytoplasma].	26.46	514	298	23	19	504	3	464	7e-11	75.5
rs:WP_008720283	Topoisomerase IA [Rhodococcus sp. AW25M09].	23.49	447	278	16	7	425	6	416	7e-11	75.9
rs:WP_012037613	DNA topoisomerase I [Clavibacter michiganensis].	22.02	554	334	18	7	505	8	518	7e-11	75.9
rs:WP_043464656	DNA topoisomerase I [Streptomyces fradiae].	23.84	558	321	23	7	505	15	527	7e-11	75.9
rs:WP_006435073	DNA topoisomerase I [Gordonia amicalis].	22.74	563	334	18	7	505	18	543	7e-11	75.9
rs:WP_026660394	DNA topoisomerase I [Butyrivibrio sp. AC2005].	24.38	443	283	19	93	505	66	486	7e-11	75.5
tr:B1II68_CLOBK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.36	546	326	21	7	517	10	503	7e-11	75.5
rs:WP_008368407	topoisomerase I [Pseudomonas sp. M47T1].	24.07	428	278	15	99	505	103	504	7e-11	75.9
rs:WP_000308597	DNA topoisomerase I subunit omega, partial [Acinetobacter baumannii].	26.09	322	197	11	205	505	1	302	7e-11	75.5
rs:WP_018536494	DNA topoisomerase I [Streptomyces sp. MspMP-M5].	25.43	460	269	19	97	505	91	527	7e-11	75.9
rs:WP_008983002	topoisomerase I [Alishewanella agri].	23.41	534	330	19	7	505	6	495	7e-11	75.9
rs:WP_006842975	DNA topoisomerase I [Dysgonomonas mossii].	23.82	550	321	21	7	523	6	490	7e-11	75.9
rs:WP_021488552	topoisomerase I [Pseudomonas mendocina].	22.12	529	352	17	7	505	6	504	7e-11	75.9
rs:WP_044323044	DNA topoisomerase I [Pseudomonas amygdali].	22.59	456	309	13	69	505	75	505	7e-11	75.9
rs:WP_016704946	topoisomerase I [Pseudomonas chlororaphis].	22.15	456	311	13	69	505	75	505	7e-11	75.9
rs:WP_021118814	DNA topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	7e-11	75.9
rs:WP_005379878	DNA topoisomerase I [Veillonella atypica].	23.79	580	349	23	7	564	69	577	7e-11	75.5
rs:WP_003446618	MULTISPECIES: topoisomerase I [Pseudomonas].	22.88	459	304	15	69	505	75	505	7e-11	75.9
rs:WP_016341720	DNA topoisomerase I subunit omega [Mycobacterium abscessus].	24.42	475	282	15	86	504	69	522	7e-11	75.9
rs:WP_043310071	DNA topoisomerase I [Pseudomonas sp. ML96].	22.81	456	308	13	69	505	74	504	7e-11	75.9
rs:WP_023794037	DNA topoisomerase [Candidatus Saccharibacteria bacterium RAAC3_TM7_1].	23.42	568	330	23	7	539	6	503	7e-11	75.5
rs:WP_045182440	DNA topoisomerase I [Elizabethkingia sp. BM10].	22.33	524	315	20	7	504	6	463	7e-11	75.9
rs:WP_036868867	DNA topoisomerase I, partial [Prevotella bivia].	28.42	190	121	4	5	186	3	185	7e-11	72.0
rs:WP_025643059	DNA topoisomerase I [Clostridiales bacterium VE202-26].	23.36	535	315	23	7	504	6	482	7e-11	75.5
rs:WP_010829322	hypothetical protein, partial [Enterococcus faecalis].	38.02	121	65	4	5	121	3	117	7e-11	70.9
rs:WP_023587330	DNA topoisomerase I [Streptomyces thermolilacinus].	23.42	555	325	21	7	505	15	525	7e-11	75.9
rs:WP_005065496	DNA topoisomerase I [Mycobacterium abscessus].	24.42	475	282	15	86	504	69	522	7e-11	75.9
rs:WP_033694419	hypothetical protein [Bacillus thuringiensis].	29.70	165	92	2	375	532	1	148	7e-11	73.9
tr:A0A090VZV9_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.67	523	306	20	7	505	6	464	7e-11	75.5
rs:WP_022318561	DNA topoisomerase [Dorea sp. CAG:317].	24.67	535	307	26	7	504	6	481	7e-11	75.5
rs:WP_004656891	topoisomerase I [Pseudomonas savastanoi].	22.37	456	310	13	69	505	75	505	8e-11	75.9
rs:WP_047302981	DNA topoisomerase I [Pseudomonas fluorescens].	22.32	457	309	14	69	505	75	505	8e-11	75.9
tr:W4LEV6_9DELT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW96235.1}; Flags: Fragment;	29.44	231	146	8	379	599	5	228	8e-11	75.1
rs:WP_016825233	DNA topoisomerase I [Streptomyces viridosporus].	23.39	560	319	23	7	505	15	525	8e-11	75.9
rs:WP_002659914	DNA topoisomerase I [Saprospira grandis].	23.22	534	318	18	7	505	6	482	8e-11	75.9
rs:WP_040033789	DNA topoisomerase I [Haemophilus influenzae].	23.45	550	327	24	3	505	2	504	8e-11	75.9
tr:E6U7W7_ETHHY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.31	543	315	23	7	505	5	495	8e-11	75.5
rs:WP_021094222	MULTISPECIES: DNA topoisomerase I [Anoxybacillus].	23.38	526	316	22	112	598	82	559	8e-11	75.5
rs:WP_014547714	DNA topoisomerase I [Francisella tularensis].	22.24	544	324	20	7	505	6	495	8e-11	75.5
gp:CP002011_2285	DNA topoisomerase [Clostridium botulinum F str. 230613]	24.36	546	326	21	7	517	10	503	8e-11	75.5
rs:WP_003226594	topoisomerase I [Pseudomonas fluorescens].	23.08	533	343	20	7	505	6	505	8e-11	75.9
rs:WP_030989852	DNA topoisomerase I [Streptomyces sp. NRRL S-1813].	24.62	459	273	18	97	505	91	526	8e-11	75.9
rs:WP_021116753	DNA topoisomerase I [Haemophilus parasuis].	23.35	454	289	18	79	505	85	506	8e-11	75.5
rs:WP_015465019	topoisomerase I [Psychromonas sp. CNPT3].	24.04	445	278	17	88	505	95	506	8e-11	75.9
rs:WP_038005493	DNA topoisomerase I [Synechococcus sp. WH 7805].	23.08	624	358	21	5	583	4	550	8e-11	75.9
rs:WP_014046845	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.54	559	327	21	7	505	15	527	8e-11	75.9
rs:WP_033886444	DNA topoisomerase I, partial [Bacteroides faecichinchillae].	23.09	524	317	18	7	504	6	469	8e-11	75.5
rs:WP_012057245	DNA topoisomerase I [Thermosipho melanesiensis].	23.88	578	334	19	7	562	8	501	8e-11	75.5
tr:X1PTH7_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S12043 {ECO:0000313|EMBL:GAI42405.1}; Flags: Fragment;	32.30	257	141	12	291	539	8	239	8e-11	72.8
rs:WP_031147671	DNA topoisomerase I [Streptomyces erythrochromogenes].	22.72	559	323	22	7	505	15	524	8e-11	75.9
rs:WP_037165268	MULTISPECIES: DNA topoisomerase I [Rhizobium].	24.55	550	312	23	4	505	1	495	8e-11	75.5
tr:A0A0B2RG64_GLYSO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.61	342	198	12	36	347	192	510	8e-11	75.1
rs:WP_009126193	DNA topoisomerase I [Bacteroides fluxus].	23.36	518	324	16	7	504	6	470	8e-11	75.5
rs:WP_005697517	topoisomerase I [Haemophilus parainfluenzae].	23.60	555	320	24	3	505	2	504	8e-11	75.5
rs:WP_002332999	MULTISPECIES: hypothetical protein [Enterococcus].	37.29	118	64	5	5	118	3	114	8e-11	70.9
tr:L1PYG3_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.62	580	350	23	7	564	72	580	8e-11	75.5
rs:WP_038351417	DNA topoisomerase I [Eubacterium limosum].	23.52	455	289	14	97	515	67	498	8e-11	75.5
tr:K1U5H1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC77523.1}; Flags: Fragment;	29.55	176	114	5	7	180	5	172	8e-11	71.6
rs:WP_032583440	DNA topoisomerase I, partial [Bacteroides fragilis].	24.68	308	199	9	4	301	2	286	8e-11	73.2
rs:WP_036497413	DNA topoisomerase I [Nocardia aobensis].	23.31	592	352	21	7	550	5	542	8e-11	75.9
rs:WP_025443402	DNA topoisomerase I [Borrelia miyamotoi].	22.46	610	355	23	1	561	1	541	8e-11	75.5
rs:WP_006589617	DNA topoisomerase I [Bartonella birtlesii].	24.73	546	308	27	7	505	4	493	8e-11	75.5
rs:WP_014925151	DNA topoisomerase I [Gordonia sp. KTR9].	23.13	549	338	17	7	505	18	532	8e-11	75.9
tr:A9BI47_PETMO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.93	580	348	24	7	564	19	521	8e-11	75.5
rs:WP_020955187	DNA topoisomerase I [Borrelia miyamotoi].	22.79	610	353	24	1	561	1	541	8e-11	75.5
tr:D3LS14_MICLU	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EFD49743.1};	26.26	198	139	3	40	237	33	223	8e-11	72.8
rs:WP_038148787	DNA topoisomerase I [Veillonella atypica].	23.62	580	350	23	7	564	69	577	8e-11	75.5
rs:WP_037265031	DNA topoisomerase I [Rhodococcus rhodnii].	23.08	546	338	19	7	504	22	533	8e-11	75.5
rs:WP_041686590	DNA topoisomerase I [Ethanoligenens harbinense].	24.31	543	315	23	7	505	15	505	8e-11	75.5
rs:WP_033609470	topoisomerase I, partial [Lactobacillus plantarum].	29.70	202	126	6	375	563	1	199	8e-11	72.4
rs:WP_022414726	DNA topoisomerase [Clostridium sp. CAG:288].	22.45	628	389	21	7	607	4	560	8e-11	75.5
rs:WP_047275656	DNA topoisomerase I [Pseudomonas fluorescens].	22.66	459	305	15	69	505	75	505	8e-11	75.5
rs:WP_012829725	DNA topoisomerase I [Haliangium ochraceum].	24.84	475	280	18	81	505	179	626	8e-11	75.5
rs:WP_038066759	DNA topoisomerase I [Thermus filiformis].	26.61	357	215	13	102	430	85	422	8e-11	75.5
rs:WP_046939159	DNA topoisomerase I [Haemophilus haemolyticus].	23.13	549	330	23	3	505	2	504	8e-11	75.5
rs:WP_038115136	DNA topoisomerase I [Veillonella sp. AS16].	24.95	529	310	24	7	504	77	549	8e-11	75.5
rs:XP_005840332	hypothetical protein GUITHDRAFT_64354, partial [Guillardia theta CCMP2712].	25.33	458	276	18	94	506	77	513	8e-11	75.5
rs:WP_012506744	DNA topoisomerase I [Prosthecochloris aestuarii].	23.63	567	318	28	5	515	14	521	8e-11	75.5
rs:WP_045092549	DNA topoisomerase I [Clostridium sp. FS41].	23.30	442	291	14	93	504	63	486	8e-11	75.5
rs:WP_046949842	DNA topoisomerase I [Haemophilus haemolyticus].	23.09	550	329	23	3	505	2	504	8e-11	75.5
rs:WP_029508697	DNA topoisomerase I [Leuconostoc fallax].	24.89	438	282	17	93	505	47	462	8e-11	75.5
rs:WP_029618624	DNA topoisomerase I [Rhizobium sp. MGL06].	24.55	550	312	23	4	505	1	495	8e-11	75.5
rs:WP_044320774	DNA topoisomerase I [Pseudomonas amygdali].	22.59	456	309	13	69	505	75	505	8e-11	75.5
rs:WP_032769233	DNA topoisomerase I [Streptomyces sp. CNS654].	22.90	559	325	21	7	505	15	527	8e-11	75.5
rs:WP_003442601	DNA topoisomerase I [Psychroflexus gondwanensis].	23.67	545	304	25	7	512	6	477	8e-11	75.5
rs:WP_009096324	topoisomerase I [Halomonas sp. GFAJ-1].	21.73	451	318	12	69	505	80	509	8e-11	75.5
rs:XP_010669508	PREDICTED: uncharacterized protein LOC104886724 isoform X1 [Beta vulgaris subsp. vulgaris].	23.39	543	324	19	36	513	400	915	8e-11	75.9
rs:WP_029485813	topoisomerase, partial [Enterococcus faecium].	38.02	121	65	5	5	121	3	117	8e-11	70.5
rs:WP_010180521	topoisomerase I [Glaciecola sp. HTCC2999].	24.54	542	329	20	7	505	6	510	9e-11	75.5
rs:WP_017196441	DNA topoisomerase I [Bartonella birtlesii].	24.73	546	308	27	7	505	4	493	9e-11	75.5
rs:WP_044462178	DNA topoisomerase I [Pseudomonas sp. MRSN12121].	22.15	456	311	13	69	505	75	505	9e-11	75.5
rs:WP_026711915	DNA topoisomerase I [Flavobacterium filum].	23.80	521	313	20	7	505	6	464	9e-11	75.5
rs:WP_019388230	DNA topoisomerase I [Arenitalea lutea].	25.33	529	293	24	7	504	6	463	9e-11	75.5
tr:A4CRQ0_SYNPV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.08	624	358	21	5	583	29	575	9e-11	75.5
rs:WP_013001771	DNA topoisomerase I [Streptomyces scabiei].	23.21	560	320	24	7	505	15	525	9e-11	75.5
rs:WP_023968539	topoisomerase I [Pseudomonas chlororaphis].	22.15	456	311	13	69	505	75	505	9e-11	75.5
rs:WP_038580619	DNA topoisomerase I [Pseudomonas chlororaphis].	22.15	456	311	13	69	505	75	505	9e-11	75.5
rs:WP_028682992	DNA topoisomerase I [Pseudomonas chlororaphis].	22.15	456	311	13	69	505	75	505	9e-11	75.5
rs:WP_025775846	DNA topoisomerase I, partial [Clostridium botulinum].	24.36	546	326	21	7	517	6	499	9e-11	75.1
rs:WP_031140379	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.78	555	323	24	7	505	15	525	9e-11	75.5
rs:WP_007921310	topoisomerase I [Pseudomonas sp. GM17].	22.15	456	311	13	69	505	75	505	9e-11	75.5
rs:WP_030957759	DNA topoisomerase I [Streptomyces sp. NRRL S-378].	22.90	559	322	22	7	505	15	524	9e-11	75.5
rs:WP_032782100	DNA topoisomerase I [Streptomyces albus].	22.90	559	325	21	7	505	15	527	9e-11	75.5
rs:WP_030004516	DNA topoisomerase I [Acholeplasma brassicae].	24.20	533	302	22	5	504	3	466	9e-11	75.1
rs:WP_038547907	DNA topoisomerase I [Synechococcus sp. KORDI-100].	23.82	550	324	19	5	505	4	507	9e-11	75.5
rs:XP_002436546	hypothetical protein SORBIDRAFT_10g004493, partial [Sorghum bicolor].	25.14	533	318	19	36	510	317	826	9e-11	75.5
rs:WP_031189528	DNA topoisomerase I [Streptomyces peucetius].	22.54	448	279	18	4	425	2	407	9e-11	75.5
rs:WP_041173293	DNA topoisomerase I [Clostridium botulinum].	24.36	546	326	21	7	517	6	499	9e-11	75.1
tr:R5Q3X4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.93	606	358	24	7	584	6	536	9e-11	75.1
rs:WP_006849198	DNA topoisomerase I [Prevotella copri].	24.49	535	297	23	7	505	6	469	9e-11	75.5
rs:WP_014408458	DNA topoisomerase I [Rickettsia rhipicephali].	23.44	546	328	23	7	510	4	501	9e-11	75.5
rs:WP_020612107	DNA topoisomerase I [Spirochaeta bajacaliforniensis].	24.64	552	328	22	1	505	1	511	9e-11	75.5
rs:WP_005092137	MULTISPECIES: DNA topoisomerase I [Mycobacterium].	24.21	475	283	15	86	504	69	522	9e-11	75.5
rs:WP_042610841	DNA topoisomerase I [Haemophilus influenzae].	22.95	549	331	23	3	505	2	504	9e-11	75.5
rs:WP_018474198	DNA topoisomerase I [Echinicola pacifica].	22.74	519	322	16	7	504	6	466	9e-11	75.5
rs:WP_044308551	DNA topoisomerase I [Pseudomonas syringae].	22.91	454	310	14	69	505	75	505	9e-11	75.5
rs:XP_003671229	hypothetical protein NDAI_0G02110 [Naumovozyma dairenensis CBS 421].	24.10	614	346	26	7	546	3	570	9e-11	75.1
rs:WP_035453817	DNA topoisomerase I [Bartonella bacilliformis].	24.31	547	309	25	7	505	4	493	9e-11	75.5
rs:WP_009047964	topoisomerase I [Pseudomonas chlororaphis].	22.15	456	311	13	69	505	75	505	9e-11	75.5
rs:WP_030846072	DNA topoisomerase I [Streptomyces sp. NRRL S-475].	23.12	558	323	23	7	505	15	525	9e-11	75.5
rs:WP_044324931	DNA topoisomerase III, partial [Pseudomonas amygdali].	26.47	272	176	10	8	271	5	260	1e-10	72.8
rs:WP_038551634	DNA topoisomerase I [Nocardia nova].	23.52	591	350	21	8	550	1	537	1e-10	75.5
rs:WP_009009111	MULTISPECIES: DNA topoisomerase I [Coprobacillus].	25.48	522	313	21	7	504	6	475	1e-10	75.1
rs:WP_006731013	DNA topoisomerase [Lactobacillus iners].	29.89	184	96	6	374	539	2	170	1e-10	72.4
rs:WP_012703691	DNA topoisomerase I [Clostridium botulinum].	24.36	546	326	21	7	517	6	499	1e-10	75.1
rs:WP_046084579	DNA topoisomerase I [Streptomyces yogyakartensis].	23.12	558	324	21	7	505	16	527	1e-10	75.5
rs:WP_036334010	DNA topoisomerase I [Modestobacter sp. KNN45-2b].	22.28	561	333	22	7	505	31	550	1e-10	75.5
rs:WP_037225084	DNA topoisomerase I [Roseomonas gilardii].	25.78	450	273	20	97	505	66	495	1e-10	75.5
rs:WP_012100386	DNA topoisomerase I [Clostridium botulinum].	24.36	546	326	21	7	517	6	499	1e-10	75.1
rs:WP_035411959	DNA topoisomerase I [Bacillus sp. SJS].	24.88	418	269	13	112	504	82	479	1e-10	75.1
rs:WP_011412723	topoisomerase I [Aster yellows witches'-broom phytoplasma].	26.54	520	290	22	19	504	3	464	1e-10	75.1
rs:WP_014870995	topoisomerase I [Marinobacter sp. BSs20148].	23.84	432	275	17	99	505	108	510	1e-10	75.5
rs:WP_005086898	DNA topoisomerase I [Mycobacterium abscessus].	24.21	475	283	15	86	504	69	522	1e-10	75.5
rs:WP_005083492	DNA topoisomerase I [Mycobacterium abscessus].	24.21	475	283	15	86	504	69	522	1e-10	75.5
rs:WP_006100088	DNA topoisomerase I [Coleofasciculus chthonoplastes].	25.51	439	265	15	107	505	90	506	1e-10	75.5
tr:A0A016WJY4_9BILA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.99	471	297	19	107	555	80	511	1e-10	75.1
rs:WP_010825641	hypothetical protein, partial [Enterococcus faecalis].	38.02	121	65	4	5	121	3	117	1e-10	70.5
rs:WP_025804224	DNA topoisomerase I [Pseudomonas chlororaphis].	22.15	456	311	13	69	505	75	505	1e-10	75.5
rs:WP_043987666	DNA topoisomerase I [Mycobacterium llatzerense].	23.18	591	353	18	7	550	17	553	1e-10	75.5
rs:WP_022460775	DNA topoisomerase [Alistipes putredinis CAG:67].	23.15	527	311	19	7	504	6	467	1e-10	75.1
rs:WP_004329382	DNA topoisomerase I [Alistipes putredinis].	23.15	527	311	19	7	504	6	467	1e-10	75.1
rs:WP_040535946	DNA topoisomerase I [Gordonia namibiensis].	23.09	550	335	19	7	505	18	530	1e-10	75.5
rs:WP_039351117	DNA topoisomerase I [Chryseobacterium jeonii].	22.46	521	318	21	7	504	6	463	1e-10	75.1
rs:WP_037048654	DNA topoisomerase I [Pseudomonas oleovorans].	22.30	538	339	21	7	505	6	503	1e-10	75.1
rs:WP_003370835	DNA topoisomerase I [Clostridium botulinum].	24.18	521	326	18	7	505	6	479	1e-10	75.1
rs:WP_041847165	DNA topoisomerase I [Bartonella bacilliformis].	24.31	547	309	25	7	505	4	493	1e-10	75.1
tr:K7MMP7_SOYBN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.61	342	198	12	36	347	268	586	1e-10	74.7
rs:WP_031128143	DNA topoisomerase I [Streptomyces sp. NRRL WC-3719].	23.16	557	324	22	7	505	15	525	1e-10	75.5
rs:WP_023557169	DNA topoisomerase I [Brevibacillus panacihumi].	23.19	526	329	20	5	504	4	480	1e-10	75.1
rs:WP_009042977	topoisomerase I [Pseudomonas chlororaphis].	22.15	456	311	13	69	505	75	505	1e-10	75.1
rs:WP_003538227	DNA topoisomerase I [Erysipelatoclostridium ramosum].	25.48	522	313	21	7	504	6	475	1e-10	75.1
rs:WP_047295278	DNA topoisomerase I [Pseudomonas fluorescens].	22.88	459	304	16	69	505	75	505	1e-10	75.1
tr:T0EC08_CLOSO	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EPZ61178.1};	26.34	224	138	9	6	218	4	211	1e-10	72.0
rs:WP_042980269	DNA topoisomerase III, partial [Vibrio owensii].	26.82	261	177	7	4	260	1	251	1e-10	72.8
tr:A0A076H187_9SYNE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.82	550	324	19	5	505	27	530	1e-10	75.5
rs:XP_010669509	PREDICTED: uncharacterized protein LOC104886724 isoform X2 [Beta vulgaris subsp. vulgaris].	23.39	543	324	19	36	513	168	683	1e-10	75.5
rs:WP_018477788	DNA topoisomerase I [Pontibacter roseus].	22.73	528	312	19	7	505	6	466	1e-10	75.1
rs:WP_016275131	DNA topoisomerase I [Bacteroides massiliensis].	23.30	528	311	23	7	504	6	469	1e-10	75.1
rs:WP_022305903	DNA topoisomerase [Roseburia sp. CAG:380].	29.21	178	115	5	7	180	6	176	1e-10	72.4
rs:WP_017826122	DNA topoisomerase I [Clostridium botulinum].	24.18	521	326	18	7	505	6	479	1e-10	75.1
rs:WP_013714771	topoisomerase I [Pseudomonas mendocina].	22.72	427	285	14	99	505	103	504	1e-10	75.1
tr:W4V4V0_9FIRM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE88435.1};	30.41	148	97	3	29	174	8	151	1e-10	71.2
tr:K7MMP5_SOYBN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.70	428	256	16	36	429	268	667	1e-10	75.1
rs:WP_019070269	DNA topoisomerase I [Streptomyces sp. R1-NS-10].	22.92	554	329	21	7	505	15	525	1e-10	75.1
rs:WP_044508780	DNA topoisomerase I [Mycobacterium simiae].	24.52	473	284	17	86	504	84	537	1e-10	75.1
rs:WP_041069001	DNA topoisomerase I [Pseudomonas sp. W15Feb9B].	22.88	459	304	16	69	505	75	505	1e-10	75.1
rs:WP_014517453	DNA topoisomerase I [Campylobacter jejuni].	24.38	525	319	21	5	505	4	474	1e-10	75.1
rs:WP_036888796	DNA topoisomerase I [Prevotella aurantiaca].	25.64	433	256	14	7	431	25	399	1e-10	75.1
rs:WP_022857371	DNA topoisomerase I [Alloscardovia omnicolens].	22.26	557	325	21	7	505	8	514	1e-10	75.1
rs:XP_002480564	DNA topoisomerase III, putative [Talaromyces stipitatus ATCC 10500].	24.87	563	337	21	7	532	6	519	1e-10	75.1
tr:C4VMX8_9LACO	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EEQ24364.1};	26.96	345	208	15	7	335	5	321	1e-10	75.1
rs:WP_027387037	DNA topoisomerase I [Chryseobacterium gregarium].	22.94	523	313	22	7	504	6	463	1e-10	75.1
rs:WP_004493282	DNA topoisomerase I [Leptospira santarosai].	22.94	523	325	18	5	505	3	469	1e-10	74.7
rs:WP_022042897	DNA topoisomerase III [Bacteroides caccae CAG:21].	31.52	184	110	7	375	550	1	176	1e-10	73.6
tr:W1FC26_ENTCL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDL31348.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL31348.1};	28.85	156	101	3	416	563	2	155	1e-10	72.0
rs:WP_028951357	DNA topoisomerase I [Synechococcus sp. CC9616].	24.00	550	323	19	5	505	4	507	1e-10	75.1
rs:WP_037000362	DNA topoisomerase I [Pseudomonas pseudoalcaligenes].	22.35	537	340	22	7	505	6	503	1e-10	75.1
rs:WP_031012614	DNA topoisomerase I [Streptomyces sp. NRRL WC-3773].	24.13	460	275	16	97	505	91	527	1e-10	75.1
tr:K7MMP6_SOYBN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.70	428	256	16	36	429	266	665	1e-10	75.1
rs:WP_029955435	DNA topoisomerase I [Atribacteria bacterium SCGC AAA255-N14].	23.15	527	329	18	7	505	6	484	1e-10	75.1
rs:WP_031367907	DNA topoisomerase I, partial [Clostridium botulinum].	23.57	543	334	19	7	517	6	499	1e-10	75.1
rs:WP_022310620	DNA topoisomerase [Prevotella sp. CAG:474].	24.81	520	312	20	7	504	6	468	1e-10	75.1
rs:WP_010603531	DNA topoisomerase type IA central domain-containing protein, partial [Pedobacter agri].	29.28	181	107	5	7	176	4	174	1e-10	71.2
tr:K6XNM9_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.40	470	289	15	86	505	65	513	1e-10	75.1
rs:WP_024947862	DNA topoisomerase I [Pseudomonas aeruginosa].	22.22	558	363	15	7	541	6	515	1e-10	75.1
rs:WP_045372432	DNA topoisomerase I [Jejuia pallidilutea].	24.71	522	305	20	7	504	6	463	1e-10	75.1
tr:K1ZHR3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.30	528	326	17	7	505	4	481	1e-10	75.1
rs:WP_033064059	DNA topoisomerase I [Clostridium botulinum].	23.57	543	334	19	7	517	6	499	1e-10	75.1
rs:WP_004891082	DNA topoisomerase I [Anoxybacillus flavithermus].	23.62	525	316	21	112	598	82	559	1e-10	75.1
tr:X0YP46_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_L01696 {ECO:0000313|EMBL:GAG58034.1}; Flags: Fragment;	24.18	459	282	17	7	445	6	418	1e-10	73.9
rs:WP_017955029	DNA topoisomerase I [actinobacterium SCGC AAA278-O22].	22.77	549	332	19	7	505	9	515	1e-10	75.1
rs:WP_019776021	hypothetical protein, partial [Streptococcus sobrinus].	26.79	224	146	5	5	219	3	217	1e-10	72.0
rs:WP_033066281	DNA topoisomerase I [Clostridium botulinum].	24.36	546	326	21	7	517	6	499	1e-10	75.1
rs:WP_045582096	DNA topoisomerase I [Azospirillum thiophilum].	23.72	548	321	21	1	505	1	494	1e-10	75.1
rs:WP_016757400	MULTISPECIES: DNA topoisomerase I [Leptospira].	22.96	527	324	18	1	504	1	468	1e-10	74.7
rs:WP_002740254	DNA topoisomerase I [Leptospira borgpetersenii].	22.96	527	324	18	1	504	1	468	1e-10	74.7
rs:WP_035815296	DNA topoisomerase I, partial [Jiangella gansuensis].	23.75	459	278	15	97	505	91	527	1e-10	75.1
rs:WP_011670006	DNA topoisomerase I [Leptospira borgpetersenii].	23.72	527	320	20	1	504	1	468	1e-10	74.7
rs:WP_043397308	DNA topoisomerase I [Mycobacterium sp. UNC280MFTsu5.1].	23.18	591	353	18	7	550	17	553	1e-10	75.1
rs:WP_025018184	DNA topoisomerase I [Bacteroides sartorii].	23.48	528	310	23	7	504	6	469	1e-10	75.1
rs:WP_032121749	DNA topoisomerase I [Clostridium sp. LF2].	23.52	540	336	18	7	517	6	497	1e-10	74.7
rs:WP_011468263	topoisomerase I [Saccharophagus degradans].	22.08	548	335	17	7	505	6	510	1e-10	75.1
rs:WP_007961815	topoisomerase I [Pseudomonas sp. GM30].	22.88	459	304	16	69	505	75	505	1e-10	75.1
rs:WP_005488609	DNA topoisomerase I [Halanaerobium saccharolyticum].	23.89	607	362	26	7	586	9	542	1e-10	74.7
rs:WP_010529083	topoisomerase [Lentibacillus jeotgali].	37.61	117	64	5	6	118	4	115	1e-10	70.1
rs:WP_030615889	DNA topoisomerase I [Streptomyces sclerotialus].	24.35	460	274	18	97	505	91	527	1e-10	75.1
rs:WP_004440643	DNA topoisomerase I [Clostridium botulinum].	23.57	543	334	19	7	517	6	499	1e-10	74.7
rs:WP_002759875	DNA topoisomerase I [Leptospira borgpetersenii].	22.96	527	324	18	1	504	1	468	1e-10	74.7
sp:TOP1_HAEIN	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	23.13	549	330	23	3	505	2	504	1e-10	75.1
rs:WP_008154288	MULTISPECIES: DNA topoisomerase I [Parabacteroides].	24.52	522	309	21	7	504	6	466	1e-10	75.1
tr:A0A0B8NR71_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM54802.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAM54802.1};	33.09	136	86	2	416	548	2	135	1e-10	70.9
tr:U1QX25_9BIFI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.26	557	325	21	7	505	22	528	1e-10	75.1
rs:WP_005631659	topoisomerase I [Haemophilus haemolyticus].	22.89	546	335	22	3	505	2	504	1e-10	75.1
rs:WP_017361524	topoisomerase I [Pseudomonas mendocina].	21.93	529	353	17	7	505	6	504	1e-10	75.1
rs:WP_019187748	DNA topoisomerase I [Candidatus Prevotella conceptionensis].	24.19	583	333	20	7	552	6	516	1e-10	75.1
rs:WP_035513040	DNA topoisomerase, partial [Lactobacillus iners].	29.89	184	96	6	374	539	27	195	1e-10	72.0
tr:C4FQQ5_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.19	525	319	22	7	504	79	551	1e-10	75.1
rs:WP_034538763	hypothetical protein, partial [Lactobacillus jensenii].	26.96	345	208	15	7	335	5	321	1e-10	74.7
rs:WP_039772798	DNA topoisomerase I [Pseudomonas fluorescens].	22.88	459	304	16	69	505	75	505	1e-10	75.1
rs:WP_020032014	hypothetical protein [gamma proteobacterium SCGC AAA300-D14].	23.74	417	281	12	107	505	117	514	1e-10	75.1
tr:A0A0B7I922_9FLAO	RecName: Full=DNA topoisomerase; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.13	518	313	22	7	504	13	470	1e-10	75.1
rs:WP_036543456	DNA topoisomerase I [Nocardioides sp. UNC345MFTsu5.1].	24.62	463	283	18	89	505	73	515	1e-10	75.1
rs:WP_024644067	DNA topoisomerase I [Pseudomonas syringae].	22.88	459	304	14	69	505	75	505	1e-10	75.1
rs:WP_007953057	MULTISPECIES: topoisomerase I [Pseudomonas].	22.88	459	304	16	69	505	75	505	1e-10	75.1
rs:WP_032077656	DNA topoisomerase I [Clostridium drakei].	24.04	545	329	18	7	517	6	499	1e-10	74.7
rs:WP_012242292	topoisomerase I [Acholeplasma laidlawii].	25.59	512	289	23	26	504	12	464	1e-10	74.7
rs:WP_031860267	DNA topoisomerase III, partial [Staphylococcus aureus].	31.29	147	91	5	7	151	5	143	1e-10	70.9
tr:A0A0B7INK9_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.13	518	313	22	7	504	13	470	1e-10	75.1
rs:WP_016644692	DNA topoisomerase 1 [Streptomyces aurantiacus].	22.94	558	324	23	7	505	15	525	1e-10	75.1
rs:WP_044418591	DNA topoisomerase I [Rhodopseudomonas palustris].	22.96	540	330	19	4	505	1	492	1e-10	75.1
rs:WP_008791761	DNA topoisomerase I [Coprobacillus sp. 8_2_54BFAA].	25.48	522	313	21	7	504	6	475	1e-10	74.7
rs:WP_025059920	DNA topoisomerase I [Sulfitobacter donghicola].	24.70	498	285	25	4	469	1	440	1e-10	75.1
rs:WP_015349034	DNA topoisomerase I [Myxococcus stipitatus].	22.86	573	321	22	7	516	81	595	1e-10	75.1
rs:WP_031103564	DNA topoisomerase I [Streptomyces sp. NRRL S-146].	22.94	558	324	23	7	505	15	525	1e-10	75.1
rs:WP_027178311	DNA topoisomerase I [Desulfovibrio bastinii].	23.82	529	317	17	7	505	6	478	1e-10	74.7
rs:WP_031921357	DNA topoisomerase III, partial [Staphylococcus aureus].	31.29	147	91	5	7	151	5	143	1e-10	70.9
rs:WP_017737335	topoisomerase I [Pseudomonas sp. CBZ-4].	22.22	459	307	14	69	505	75	505	1e-10	75.1
rs:WP_022008214	DNA topoisomerase [Coprobacillus sp. CAG:183].	25.48	522	313	21	7	504	6	475	1e-10	74.7
rs:WP_005691979	topoisomerase I [Haemophilus influenzae].	22.89	546	335	22	3	505	2	504	1e-10	75.1
rs:WP_027494171	topoisomerase I [Rhodococcus sp. JG-3].	23.15	445	282	15	7	425	6	416	1e-10	74.7
rs:WP_028972477	hypothetical protein [Spirochaeta cellobiosiphila].	25.00	504	308	21	93	547	73	555	1e-10	74.7
rs:WP_011117558	DNA topoisomerase I [Campylobacter jejuni].	24.38	525	319	21	5	505	4	474	1e-10	74.7
rs:WP_007858081	DNA topoisomerase I [[Clostridium] citroniae].	23.54	446	285	15	93	504	63	486	1e-10	74.7
rs:WP_021668982	DNA topoisomerase, partial [Prevotella disiens].	29.76	168	103	4	376	531	28	192	1e-10	72.8
rs:WP_030801500	DNA topoisomerase I [Streptomyces sp. NRRL S-337].	24.35	460	274	18	97	505	91	527	1e-10	75.1
rs:WP_009032645	DNA topoisomerase I [Indibacter alkaliphilus].	23.33	523	316	19	7	505	6	467	1e-10	74.7
rs:WP_042344952	DNA topoisomerase I [Capnocytophaga canimorsus].	24.13	518	313	22	7	504	6	463	1e-10	74.7
rs:WP_025952447	DNA topoisomerase I, partial [Prochlorococcus sp. scB243_495P20].	25.17	449	266	16	101	505	85	507	1e-10	74.3
rs:WP_030651823	DNA topoisomerase I [Streptomyces rimosus].	24.35	460	274	18	97	505	91	527	1e-10	75.1
rs:WP_043522729	DNA topoisomerase I [Actinoplanes utahensis].	22.43	575	329	22	7	512	11	537	1e-10	75.1
rs:WP_031878374	DNA topoisomerase III, partial [Staphylococcus aureus].	31.29	147	91	5	7	151	5	143	1e-10	70.9
rs:WP_036885723	DNA topoisomerase I [Prevotella melaninogenica].	24.48	531	308	21	7	505	6	475	1e-10	74.7
rs:WP_044730147	DNA topoisomerase I [Mycoplasma hominis].	20.87	508	331	15	7	500	6	456	1e-10	74.7
rs:WP_039774455	DNA topoisomerase I [Clostridium botulinum].	24.18	546	327	20	7	517	6	499	1e-10	74.7
rs:WP_030895377	DNA topoisomerase I [Streptomyces sp. NRRL F-5053].	22.62	473	313	20	4	457	2	440	1e-10	74.7
rs:WP_042006265	DNA topoisomerase I [Capnocytophaga canimorsus].	24.13	518	313	22	7	504	6	463	1e-10	74.7
gpu:CP009530_2314	DNA topoisomerase I [Methanosarcina barkeri 227]	24.58	537	320	21	48	548	52	539	1e-10	74.7
rs:WP_031880389	DNA topoisomerase III, partial [Staphylococcus aureus].	31.29	147	91	5	7	151	5	143	1e-10	70.9
rs:WP_030359673	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.86	560	322	22	7	505	15	525	1e-10	74.7
rs:WP_008720593	Topoisomerase IA [Rhodococcus sp. AW25M09].	23.49	447	278	16	7	425	6	416	1e-10	74.7
rs:WP_003035615	DNA topoisomerase I [Francisella tularensis].	22.43	544	323	20	7	505	6	495	1e-10	74.7
rs:WP_033970640	DNA topoisomerase I [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	1e-10	74.7
rs:WP_025796828	DNA topoisomerase I [Prevotella saccharolytica].	24.72	530	300	20	7	504	6	468	1e-10	74.7
rs:WP_046284851	DNA topoisomerase I [Mycobacterium sp. UM_NZ2].	23.77	467	291	15	86	504	85	534	1e-10	74.7
rs:WP_022343868	DNA topoisomerase [Clostridium sp. CAG:356].	23.05	538	345	17	97	606	67	563	1e-10	74.7
rs:WP_039969181	DNA topoisomerase I [Veillonella dispar].	24.19	525	319	22	7	504	76	548	1e-10	74.7
tr:T1A8I6_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD53133.1}; Flags: Fragment;	26.22	225	149	8	278	495	17	231	1e-10	71.6
rs:WP_028239585	DNA topoisomerase I [Pseudomonas azotifigens].	22.79	544	329	19	7	505	6	503	1e-10	74.7
rs:WP_024681926	DNA topoisomerase I [Pseudomonas syringae].	22.96	453	311	12	69	505	75	505	1e-10	74.7
rs:WP_028470945	DNA topoisomerase I [Neptunomonas japonica].	21.87	471	313	14	69	512	79	521	1e-10	74.7
rs:WP_017677648	topoisomerase I [Pseudomonas alcaliphila].	22.72	427	285	14	99	505	103	504	1e-10	74.7
tr:V7Z0V9_LACPN	SubName: Full=Topoisomerase I {ECO:0000313|EMBL:ETC79988.1};	28.63	241	148	8	377	603	2	232	1e-10	73.2
rs:WP_027698391	DNA topoisomerase I [Weissella oryzae].	22.81	456	284	14	7	427	6	428	1e-10	74.7
rs:WP_041346435	topoisomerase I, partial [Oenococcus oeni].	30.85	201	123	6	376	563	17	214	1e-10	72.8
tr:S6V5Y6_PSESF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.96	453	311	12	69	505	32	462	1e-10	74.7
tr:D3I2I7_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.48	531	308	21	7	505	8	477	1e-10	74.7
rs:WP_037512036	DNA topoisomerase I [Sphingopyxis sp. LC81].	24.04	520	326	17	7	505	4	475	1e-10	74.7
rs:WP_002333457	hypothetical protein [Enterococcus faecium].	38.14	118	63	5	5	118	3	114	2e-10	70.1
rs:WP_025390203	DNA topoisomerase I [Pseudomonas syringae].	22.88	459	304	14	69	505	75	505	2e-10	74.7
rs:WP_033997592	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	23.98	367	231	11	204	553	8	343	2e-10	73.9
rs:WP_026283306	DNA topoisomerase I [Rhizobium sp. 2MFCol3.1].	27.27	462	248	23	107	510	75	506	2e-10	74.7
rs:WP_002725647	DNA topoisomerase I [Leptospira borgpetersenii].	22.96	527	324	18	1	504	1	468	2e-10	74.3
rs:WP_036434129	DNA topoisomerase I [Mycoplasma columborale].	22.41	540	340	20	1	514	1	487	2e-10	74.3
rs:WP_002733581	DNA topoisomerase I [Leptospira borgpetersenii].	22.96	527	324	18	1	504	1	468	2e-10	74.3
rs:WP_030543868	DNA topoisomerase I [Streptomyces albus].	23.84	558	321	23	7	505	15	527	2e-10	74.7
tr:C9AKL3_ENTFC	SubName: Full=Type 1 topoisomerase {ECO:0000313|EMBL:EEV60553.1};	28.24	170	112	5	52	218	2	164	2e-10	71.2
rs:WP_005738758	MULTISPECIES: topoisomerase I [Pseudomonas syringae group].	22.96	453	311	12	69	505	75	505	2e-10	74.7
rs:WP_031382963	DNA topoisomerase I [Halomonas zincidurans].	22.20	473	324	14	53	505	62	510	2e-10	74.7
rs:WP_005872450	DNA topoisomerase I [Actinomyces georgiae].	23.21	573	323	22	1	505	1	524	2e-10	74.7
rs:WP_005641907	topoisomerase I [Haemophilus haemolyticus].	23.50	549	328	23	3	505	2	504	2e-10	74.7
rs:WP_036431931	DNA topoisomerase I [Mycobacterium mageritense].	23.15	596	347	21	7	550	18	554	2e-10	74.7
rs:WP_022072476	DNA topoisomerase [Clostridium bartlettii CAG:1329].	23.67	528	319	22	7	504	6	479	2e-10	74.3
rs:WP_002708740	DNA topoisomerase I [Thiothrix nivea].	24.63	536	319	18	7	505	6	493	2e-10	74.7
rs:WP_046831272	DNA topoisomerase I [Xanthomonas axonopodis].	23.78	492	313	19	43	505	25	483	2e-10	74.7
rs:WP_037150123	DNA topoisomerase I [Rhizobium sp. YS-1r].	25.44	456	264	22	107	510	75	506	2e-10	74.7
rs:WP_023171015	DNA topoisomerase III, partial [Salmonella enterica].	25.93	270	174	9	7	267	4	256	2e-10	71.6
rs:WP_032602805	DNA topoisomerase I, partial [Bacteroides fragilis].	27.92	240	149	7	7	237	4	228	2e-10	72.0
rs:WP_026680881	DNA topoisomerase I [Bacillus megaterium].	25.94	424	261	13	112	505	82	482	2e-10	74.3
rs:WP_043156147	DNA topoisomerase I [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	2e-10	74.7
rs:WP_003380888	topoisomerase I [Pseudomonas syringae].	22.69	454	311	12	69	505	75	505	2e-10	74.7
rs:WP_037220614	DNA topoisomerase I [Rhizobium sp. YR060].	24.20	562	316	25	4	510	1	507	2e-10	74.7
rs:WP_009757221	DNA topoisomerase I [Lachnospiraceae bacterium 2_1_46FAA].	23.98	442	283	18	93	504	63	481	2e-10	74.3
rs:WP_014061723	DNA topoisomerase I [Streptomyces violaceusniger].	22.94	558	325	21	7	505	16	527	2e-10	74.7
rs:XP_003738127	PREDICTED: DNA topoisomerase 3-beta-1-like [Metaseiulus occidentalis].	24.35	460	289	18	112	553	119	537	2e-10	74.7
rs:WP_009410590	DNA topoisomerase I [Capnocytophaga sp. oral taxon 324].	22.61	522	316	18	7	504	6	463	2e-10	74.7
rs:WP_023512787	DNA topoisomerase 1 [Shinella sp. DD12].	24.16	563	314	27	4	510	1	506	2e-10	74.7
rs:WP_017684584	topoisomerase I [Pseudomonas syringae].	22.69	454	311	12	69	505	75	505	2e-10	74.7
rs:WP_042506432	DNA topoisomerase I [Algibacter lectus].	24.66	519	310	18	7	504	6	464	2e-10	74.7
tr:B9JDL6_AGRRK	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.20	562	316	25	4	510	2	508	2e-10	74.7
rs:WP_006530388	DNA topoisomerase I [Gloeocapsa sp. PCC 73106].	24.89	446	268	17	103	505	86	507	2e-10	74.7
tr:A0A073BTT1_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KEI54916.1};	28.24	170	112	5	52	218	2	164	2e-10	70.9
rs:WP_019332831	topoisomerase I [Pseudomonas syringae].	22.47	454	312	12	69	505	75	505	2e-10	74.7
rs:WP_032576958	DNA topoisomerase I, partial [Bacteroides fragilis].	23.93	351	223	13	167	498	1	326	2e-10	72.8
rs:WP_030709415	DNA topoisomerase I [Streptomyces sp. NRRL F-2580].	22.54	559	324	22	7	505	15	524	2e-10	74.7
rs:WP_031623081	DNA topoisomerase III, partial [Salmonella enterica].	25.93	270	174	9	7	267	4	256	2e-10	71.6
rs:WP_034297059	DNA topoisomerase I [Alloscardovia omnicolens].	22.26	557	325	21	7	505	8	514	2e-10	74.7
rs:WP_031369395	DNA topoisomerase I, partial [Clostridium botulinum].	23.57	543	334	19	7	517	6	499	2e-10	74.3
rs:WP_046951562	DNA topoisomerase I [Leptospira santarosai].	23.21	530	315	20	5	505	3	469	2e-10	74.3
gpu:CP008746_1387	DNA topoisomerase I TopA2 [Methanosarcina barkeri CM1]	24.30	535	324	21	48	548	52	539	2e-10	74.7
rs:WP_011620028	DNA topoisomerase I [Synechococcus sp. CC9311].	23.43	542	336	18	5	505	4	507	2e-10	74.7
tr:U2KJL7_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.76	517	317	18	7	504	8	471	2e-10	74.3
rs:WP_024658808	DNA topoisomerase I [Pseudomonas syringae].	22.96	453	311	12	69	505	75	505	2e-10	74.7
rs:WP_007692049	MULTISPECIES: DNA topoisomerase I [Rhizobium/Agrobacterium group].	24.20	562	316	25	4	510	1	507	2e-10	74.7
rs:WP_008885444	DNA topoisomerase I [Citreicella sp. SE45].	23.74	476	293	18	4	460	1	425	2e-10	74.7
tr:A0A0A1MVM7_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.42	521	345	20	7	498	8	503	2e-10	74.3
rs:WP_032386860	topoisomerase I [Rhodococcus fascians].	24.33	448	273	16	7	425	6	416	2e-10	74.3
rs:WP_022439538	DNA topoisomerase [Clostridium sp. CAG:411].	22.22	540	313	24	7	504	6	480	2e-10	74.3
rs:WP_040054253	DNA topoisomerase I [Candidatus Atelocyanobacterium thalassa].	23.62	470	293	15	89	512	72	521	2e-10	74.7
rs:WP_033975944	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.54	488	320	13	69	541	73	517	2e-10	74.7
tr:A0A0B2QRV0_GLYSO	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:KHN24376.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHN24376.1};	27.34	289	171	9	36	305	192	460	2e-10	74.3
rs:WP_034518694	DNA topoisomerase I [Agrobacterium rhizogenes].	24.20	562	316	25	4	510	1	507	2e-10	74.7
rs:WP_010449613	topoisomerase I [Pseudomonas fuscovaginae].	21.93	456	312	13	69	505	75	505	2e-10	74.3
rs:WP_002815553	hypothetical protein, partial [Campylobacter coli].	24.81	524	317	21	5	505	4	473	2e-10	73.9
rs:WP_014887830	topoisomerase I [secondary endosymbiont of Ctenarytaina eucalypti].	24.15	530	331	18	7	505	6	495	2e-10	74.3
tr:T0MDS8_9SPHI	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EQB80794.1};	30.05	183	116	6	376	552	12	188	2e-10	72.8
rs:WP_014549399	DNA topoisomerase I [Francisella tularensis].	22.43	544	323	20	7	505	6	495	2e-10	74.3
rs:WP_030412618	DNA topoisomerase I [Streptomyces sp. NRRL S-1448].	24.57	460	273	18	97	505	91	527	2e-10	74.7
rs:WP_031883535	DNA topoisomerase III, partial [Staphylococcus aureus].	31.29	147	91	5	7	151	5	143	2e-10	70.5
rs:WP_038608548	DNA topoisomerase I [Bacteroides dorei].	23.09	524	317	22	7	504	6	469	2e-10	74.3
rs:WP_026303996	DNA topoisomerase I [Kaistia granuli].	26.47	442	257	21	107	505	75	491	2e-10	74.7
rs:WP_040211709	DNA topoisomerase I [Clostridium sp. MS1].	24.58	533	309	21	7	505	6	479	2e-10	74.3
rs:WP_034554136	DNA topoisomerase I [Capnocytophaga sp. oral taxon 335].	22.59	518	321	16	7	504	6	463	2e-10	74.3
rs:WP_012797070	DNA topoisomerase I [Capnocytophaga ochracea].	22.59	518	321	16	7	504	6	463	2e-10	74.3
rs:WP_005693995	DNA topoisomerase I [Haemophilus influenzae].	23.13	549	330	23	3	505	2	504	2e-10	74.3
rs:WP_021659817	DNA topoisomerase I [Clostridium sp. ATCC 29733].	22.45	539	318	23	7	505	5	483	2e-10	74.3
rs:WP_033102341	DNA topoisomerase I [Thermoactinomyces daqus].	23.54	531	317	22	7	504	6	480	2e-10	74.3
tr:A0A0B8PX27_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM69257.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAM69257.1};	29.19	209	123	7	8	206	6	199	2e-10	71.2
rs:WP_015222548	DNA topoisomerase I [Cyanobacterium stanieri].	23.12	545	334	17	5	505	3	506	2e-10	74.3
rs:WP_036885478	DNA topoisomerase I, partial [Prevotella disiens].	27.14	210	130	6	334	531	1	199	2e-10	73.2
rs:WP_004286415	DNA topoisomerase I [Francisella philomiragia].	22.37	541	327	20	7	505	6	495	2e-10	74.3
rs:WP_001896186	DNA topoisomerase 3, partial [Vibrio cholerae].	28.96	183	116	6	8	184	6	180	2e-10	70.9
rs:WP_016479051	DNA topoisomerase I [Capnocytophaga sp. oral taxon 336].	22.59	518	321	16	7	504	6	463	2e-10	74.3
rs:WP_042599491	DNA topoisomerase I [Haemophilus influenzae].	24.34	452	288	18	79	505	82	504	2e-10	74.3
tr:A0A0A1PJ72_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.27	548	321	23	3	505	2	500	2e-10	74.3
rs:WP_044420078	DNA topoisomerase I [Pseudomonas syringae group genomosp. 3].	22.98	457	306	13	69	505	75	505	2e-10	74.3
rs:WP_015783361	DNA topoisomerase I [Cyanothece sp. PCC 8802].	26.00	477	271	20	80	505	61	506	2e-10	74.3
rs:WP_042594037	DNA topoisomerase I [Haemophilus influenzae].	24.34	452	288	18	79	505	82	504	2e-10	74.3
tr:G3DT94_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	23.35	394	263	13	88	467	94	462	2e-10	73.6
rs:WP_034718510	DNA topoisomerase I [Chryseobacterium antarcticum].	22.39	527	311	23	7	504	6	463	2e-10	74.3
rs:WP_045167865	DNA topoisomerase I [Prevotella intermedia].	23.66	524	319	17	7	504	6	474	2e-10	74.3
rs:WP_020374729	hypothetical protein [Sulfobacillus thermosulfidooxidans].	23.23	538	319	20	7	504	8	491	2e-10	74.3
rs:WP_009789155	DNA topoisomerase I [Synechococcus sp. BL107].	23.18	617	358	20	5	579	4	546	2e-10	74.3
rs:WP_008743043	DNA topoisomerase I [Streptomyces sp. Mg1].	22.54	559	324	22	7	505	15	524	2e-10	74.3
rs:WP_012594201	DNA topoisomerase I [Cyanothece sp. PCC 8801].	26.00	477	271	20	80	505	61	506	2e-10	74.3
rs:WP_033321736	DNA topoisomerase I [Streptomyces yerevanensis].	23.52	557	322	22	7	505	15	525	2e-10	74.3
rs:WP_014130772	DNA topoisomerase I [Pelagibacterium halotolerans].	23.78	635	360	26	4	595	1	554	2e-10	74.3
rs:WP_026644748	DNA topoisomerase I [Bifidobacterium sp. AGR2158].	22.08	566	334	22	7	510	8	528	2e-10	74.3
tr:L1MU76_9BACT	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EKX94519.1};	22.82	241	163	4	5	237	3	228	2e-10	72.0
rs:WP_043864567	DNA topoisomerase I [Pseudomonas putida].	22.59	425	288	13	99	505	102	503	2e-10	74.3
rs:WP_030866109	DNA topoisomerase I [Streptomyces sp. NRRL F-2747].	22.54	559	324	22	7	505	15	524	2e-10	74.3
rs:WP_045025600	DNA topoisomerase I [Draconibacterium sp. JN14CK-3].	22.12	529	316	19	7	504	6	469	2e-10	74.3
rs:WP_024038270	DNA topoisomerase [Intestinibacter bartlettii].	22.52	635	385	25	7	607	6	567	2e-10	74.3
rs:WP_031875549	DNA topoisomerase III, partial [Staphylococcus aureus].	31.29	147	91	5	7	151	5	143	2e-10	70.5
rs:WP_041534416	DNA topoisomerase I [Petrotoga mobilis].	22.97	579	347	24	8	564	1	502	2e-10	74.3
rs:WP_009418982	DNA topoisomerase I [Capnocytophaga sp. oral taxon 380].	22.61	522	316	18	7	504	6	463	2e-10	74.3
rs:WP_004382933	DNA topoisomerase I [Prevotella veroralis].	24.65	576	344	22	7	552	6	521	2e-10	74.3
rs:WP_020313017	DNA topoisomerase I subunit omega [Pseudomonas syringae].	22.69	454	311	12	69	505	75	505	2e-10	74.3
tr:E4MS88_CAPOC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.61	522	316	18	7	504	26	483	2e-10	74.3
rs:WP_026945101	DNA topoisomerase I [Algoriphagus marincola].	22.48	525	325	16	3	505	2	466	2e-10	74.3
rs:WP_030668102	DNA topoisomerase I [Streptomyces cellulosae].	23.30	558	322	24	7	505	15	525	2e-10	74.3
rs:WP_010620889	topoisomerase IA, partial [Lactobacillus malefermentans].	35.43	127	72	4	5	127	3	123	2e-10	69.7
rs:WP_033858678	DNA topoisomerase III, partial [Staphylococcus aureus].	31.29	147	91	5	7	151	5	143	2e-10	70.5
rs:WP_044132021	DNA topoisomerase I, partial [Bacteroides fragilis].	25.78	450	273	16	83	504	4	420	2e-10	73.6
rs:WP_018694136	hypothetical protein [Algicola sagamiensis].	24.75	497	308	20	73	543	45	501	2e-10	74.3
rs:WP_029391222	DNA topoisomerase I [Streptomyces xiaopingdaonensis].	23.90	456	282	17	97	505	90	527	2e-10	74.3
rs:WP_006780289	DNA topoisomerase I [[Clostridium] hathewayi].	23.94	447	279	16	93	504	63	483	2e-10	74.3
rs:WP_031872486	DNA topoisomerase III, partial [Staphylococcus aureus].	31.29	147	91	5	7	151	5	143	2e-10	70.5
tr:B7A9J7_THEAQ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.37	544	315	24	3	505	24	517	2e-10	74.3
rs:WP_022484853	DNA topoisomerase [Fusobacterium sp. CAG:815].	25.00	472	293	17	88	518	70	521	2e-10	74.3
rs:WP_015702243	topoisomerase I [Haemophilus influenzae].	23.13	549	330	23	3	505	2	504	2e-10	74.3
rs:WP_011360529	DNA topoisomerase I [Synechococcus sp. CC9902].	23.18	617	358	20	5	579	4	546	2e-10	74.3
rs:WP_037426547	DNA topoisomerase I, partial [Shewanella sp. POL2].	25.66	378	237	15	147	505	7	359	2e-10	74.3
rs:WP_015124680	DNA topoisomerase I [Synechococcus sp. PCC 6312].	24.68	547	323	21	5	505	3	506	2e-10	74.3
tr:W8IA30_ENSAD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.10	554	317	22	3	505	2	497	2e-10	74.3
rs:WP_040684450	DNA topoisomerase I [Thermus aquaticus].	25.37	544	315	24	3	505	12	505	2e-10	74.3
rs:WP_022232935	DNA topoisomerase [Bacteroides sp. CAG:443].	22.71	524	315	19	7	504	6	465	2e-10	74.3
rs:WP_008570827	topoisomerase I [Pseudomonas sp. Chol1].	22.10	525	355	16	7	505	6	502	2e-10	74.3
rs:WP_026979520	DNA topoisomerase I [Flavobacterium suncheonense].	23.43	525	308	21	7	504	6	463	2e-10	74.3
rs:WP_009421909	DNA topoisomerase I [Capnocytophaga sp. oral taxon 412].	22.61	522	316	18	7	504	6	463	2e-10	74.3
rs:WP_037177574	DNA topoisomerase I [Rhizobium sp. YR519].	27.06	462	249	22	107	510	75	506	2e-10	74.3
rs:WP_044002451	DNA topoisomerase I [Hymenobacter swuensis].	24.08	436	257	17	7	431	6	378	2e-10	74.3
rs:WP_031164975	DNA topoisomerase I [Streptomyces durhamensis].	23.78	555	323	24	7	505	15	525	2e-10	74.3
rs:WP_034556294	DNA topoisomerase I [Capnocytophaga ochracea].	22.61	522	316	18	7	504	6	463	2e-10	74.3
rs:WP_003712550	DNA topoisomerase, partial [Lactobacillus oris].	26.83	246	157	9	221	455	3	236	2e-10	71.2
rs:WP_009425403	DNA topoisomerase I [Neisseria sp. oral taxon 020].	23.25	542	330	18	7	510	6	499	2e-10	74.3
rs:WP_011128730	DNA topoisomerase I [Synechococcus sp. WH 8102].	24.76	525	294	19	97	579	81	546	2e-10	74.3
tr:J1GV42_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.59	518	321	16	7	504	26	483	2e-10	74.3
rs:WP_006608773	DNA topoisomerase I [Mycoplasma columbinum].	25.00	500	320	18	97	564	68	544	2e-10	73.9
rs:WP_009248640	DNA topoisomerase I [Lachnospiraceae bacterium 5_1_57FAA].	22.83	530	324	24	7	504	6	482	2e-10	73.9
rs:WP_031640548	DNA topoisomerase I [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	2e-10	74.3
rs:WP_006943967	DNA topoisomerase I [Dermacoccus sp. Ellin185].	23.40	547	334	21	7	505	8	517	2e-10	74.3
rs:WP_032577053	DNA topoisomerase I, partial [Bacteroides fragilis].	23.47	392	232	16	167	536	1	346	2e-10	73.2
tr:D4RFQ4_ENTFC	SubName: Full=Topoisomerase {ECO:0000313|EMBL:EFF27246.1};	32.48	157	98	3	414	563	8	163	2e-10	72.4
tr:A6EMW3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.82	529	304	19	7	504	6	466	2e-10	74.3
rs:WP_010844242	DNA topoisomerase I subunit omega [Gordonia terrae].	22.95	549	339	17	7	505	18	532	2e-10	74.3
rs:WP_019707577	DNA topoisomerase I [Streptomyces xinghaiensis].	23.66	558	322	23	7	505	15	527	2e-10	74.3
rs:WP_028086981	DNA topoisomerase I [Dorea longicatena].	23.78	534	314	23	7	504	6	482	2e-10	73.9
rs:WP_016475614	DNA topoisomerase I [Veillonella sp. HPA0037].	23.62	580	350	23	7	564	69	577	2e-10	73.9
rs:WP_009834706	topoisomerase I [Marinomonas sp. MED121].	22.22	531	358	17	69	584	78	568	2e-10	74.3
tr:L9PR83_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELX66133.1};	28.72	188	117	5	375	550	1	183	2e-10	72.4
rs:WP_038013874	DNA topoisomerase I [Synechococcus sp. WH 8016].	23.76	543	333	17	5	505	4	507	2e-10	74.3
rs:WP_004627000	DNA topoisomerase I [[Clostridium] termitidis].	24.31	580	335	23	7	553	6	514	2e-10	73.9
tr:W4RS51_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE46703.1};	27.92	240	133	8	375	603	32	242	2e-10	72.8
rs:WP_030299335	DNA topoisomerase I [Streptomyces katrae].	22.54	559	324	22	7	505	15	524	2e-10	74.3
tr:A0A0D6DDF9_STAAU	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:BAR08694.1};	27.98	336	199	15	198	505	5	325	2e-10	73.6
rs:WP_045311571	DNA topoisomerase I [Lechevalieria aerocolonigenes].	22.64	561	340	22	7	510	21	544	2e-10	74.3
rs:WP_036907504	DNA topoisomerase I [Prevotella salivae].	24.76	517	317	18	7	504	6	469	2e-10	73.9
rs:WP_035735116	DNA topoisomerase I [Francisella philomiragia].	22.55	541	326	20	7	505	6	495	2e-10	73.9
rs:WP_046148222	DNA topoisomerase I [Parabacteroides sp. HGS0025].	24.38	562	332	21	7	539	6	503	2e-10	73.9
rs:WP_042516839	DNA topoisomerase I [Francisella philomiragia].	22.55	541	326	20	7	505	6	495	2e-10	73.9
rs:WP_040186246	DNA topoisomerase I [Halomonas salina].	22.12	538	353	16	7	505	6	516	2e-10	74.3
rs:WP_025426616	DNA topoisomerase I [Ensifer adhaerens].	23.15	553	316	22	4	505	1	495	2e-10	74.3
rs:WP_021907930	DNA topoisomerase [Eubacterium sp. CAG:146].	22.65	446	284	16	93	504	63	481	2e-10	73.9
gpu:KM982402_222	topoisomerase I [Acanthamoeba polyphaga mimivirus]	26.85	406	217	18	7	389	5	353	2e-10	73.9
rs:WP_013657322	DNA topoisomerase I [Cellulosilyticum lentocellum].	25.21	468	282	19	97	539	67	491	2e-10	73.9
rs:WP_011961921	topoisomerase I [Haemophilus influenzae].	24.34	452	288	18	79	505	82	504	2e-10	73.9
rs:WP_044226506	DNA topoisomerase I [Coprobacter sp. 177].	24.33	563	332	24	7	539	6	504	2e-10	73.9
rs:WP_013889345	DNA topoisomerase I [Corynebacterium resistens].	25.53	474	278	20	89	505	77	532	2e-10	74.3
rs:WP_030152667	DNA topoisomerase I [Streptomyces sp. NRRL S-244].	22.54	559	324	22	7	505	15	524	2e-10	74.3
rs:WP_006365751	DNA topoisomerase I [Chlorobium ferrooxidans].	22.92	554	332	24	5	512	14	518	2e-10	73.9
rs:XP_009363705	PREDICTED: uncharacterized protein LOC103953658 [Pyrus x bretschneideri].	27.11	343	196	14	36	347	371	690	2e-10	73.9
rs:WP_011744019	DNA topoisomerase I [Chlorobium phaeobacteroides].	22.22	558	337	22	5	515	14	521	2e-10	73.9
rs:WP_028729778	DNA topoisomerase I [Parabacteroides gordonii].	24.38	562	332	21	7	539	6	503	2e-10	73.9
rs:WP_015399038	DNA topoisomerase I [Bartonella vinsonii].	23.96	551	312	27	4	505	1	493	2e-10	73.9
rs:WP_025489727	DNA topoisomerase I [Clostridiales bacterium VE202-27].	23.58	441	288	18	93	504	63	483	2e-10	73.9
rs:WP_009505253	DNA topoisomerase I [Citreicella sp. 357].	26.09	345	197	14	4	335	1	300	2e-10	73.9
rs:WP_038569546	DNA topoisomerase I [Dermacoccus nishinomiyaensis].	23.40	547	334	21	7	505	8	517	2e-10	73.9
rs:WP_027978427	DNA topoisomerase I [gamma proteobacterium L18].	23.36	428	281	14	99	505	103	504	2e-10	73.9
rs:WP_036068320	DNA topoisomerase I [Leuconostoc pseudomesenteroides].	23.50	532	315	23	7	505	22	494	2e-10	73.9
rs:WP_006778033	DNA topoisomerase III, partial [[Clostridium] hathewayi].	28.74	174	117	5	260	429	28	198	2e-10	70.5
rs:WP_004913035	DNA topoisomerase I [Leuconostoc pseudomesenteroides].	23.50	532	315	23	7	505	27	499	2e-10	73.9
rs:WP_024933161	DNA topoisomerase I [Clostridium botulinum].	23.39	543	335	18	7	517	6	499	2e-10	73.9
rs:WP_035759241	DNA topoisomerase I [Granulicoccus phenolivorans].	24.25	569	323	28	2	505	6	531	2e-10	73.9
rs:WP_015398003	DNA topoisomerase I [Bartonella australis].	24.62	455	271	19	97	505	65	493	2e-10	73.9
tr:G9QZP6_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHM92695.1};	27.81	169	113	5	398	559	5	171	2e-10	70.5
rs:WP_036885373	DNA topoisomerase I, partial [Prevotella disiens].	27.49	211	130	5	4	206	2	197	2e-10	70.5
rs:WP_012279897	DNA topoisomerase I [Francisella philomiragia].	22.55	541	326	20	7	505	6	495	2e-10	73.9
rs:WP_009544062	MULTISPECIES: DNA topoisomerase I [Cyanothece].	24.89	470	281	18	91	512	74	519	3e-10	73.9
tr:J9H0M7_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJX09208.1};	23.76	526	311	19	7	504	16	479	3e-10	73.9
rs:WP_003827625	DNA topoisomerase I [Bifidobacterium angulatum].	21.53	562	335	21	7	505	8	526	3e-10	73.9
tr:F4BRM5_CARS1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	26.35	334	207	11	198	504	5	326	3e-10	73.6
rs:WP_015816444	DNA topoisomerase I [Neorickettsia risticii].	23.33	613	366	27	4	580	1	545	3e-10	73.9
tr:L2Q8S0_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELB50338.1};	31.07	177	109	6	5	174	3	173	3e-10	70.9
rs:WP_010012760	topoisomerase I [Lactobacillus coryniformis].	22.30	444	304	13	7	427	6	431	3e-10	73.9
rs:WP_046777872	DNA topoisomerase I [Streptomyces sp. fd2-tb].	23.04	560	320	22	7	505	15	524	3e-10	73.9
rs:WP_046486836	DNA topoisomerase I [Methylophilaceae bacterium MMS-2-53].	23.36	535	327	16	7	504	5	493	3e-10	73.9
rs:WP_027383415	DNA topoisomerase I [Chryseobacterium caeni].	23.43	525	308	25	7	504	6	463	3e-10	73.9
rs:WP_032526743	DNA topoisomerase I [Prochlorococcus marinus].	25.15	513	299	18	101	579	85	546	3e-10	73.9
rs:WP_003679272	topoisomerase I [Lactobacillus coryniformis].	22.30	453	293	15	7	427	6	431	3e-10	73.9
rs:WP_008824362	hypothetical protein, partial [Prevotella histicola].	27.98	168	106	4	376	531	24	188	3e-10	72.4
rs:WP_024675102	DNA topoisomerase I [Pseudomonas syringae].	23.21	461	300	15	69	505	75	505	3e-10	73.9
rs:WP_036253930	MULTISPECIES: DNA topoisomerase I, partial [Mesorhizobium].	23.87	553	309	25	4	505	1	492	3e-10	73.9
tr:G4FJ28_9SYNE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.76	543	333	17	5	505	27	530	3e-10	73.9
rs:WP_045920564	DNA topoisomerase I [Bifidobacterium angulatum].	21.53	562	335	21	7	505	8	526	3e-10	73.9
rs:WP_014781568	DNA topoisomerase I [Aequorivita sublithincola].	23.30	528	310	20	7	505	6	467	3e-10	73.9
rs:WP_044345697	DNA topoisomerase I [Haemophilus influenzae].	23.13	549	330	23	3	505	2	504	3e-10	73.9
rs:WP_013331964	topoisomerase I [Halomonas elongata].	22.32	457	311	13	69	505	80	512	3e-10	73.9
rs:WP_017660177	DNA topoisomerase I [Geitlerinema sp. PCC 7105].	24.13	518	298	19	89	566	72	534	3e-10	73.9
rs:WP_035991054	DNA topoisomerase I [Leptolyngbya sp. KIOST-1].	24.18	550	330	15	65	579	48	545	3e-10	73.9
rs:WP_044171393	DNA topoisomerase I [Flectobacillus major].	24.12	427	264	12	7	430	6	375	3e-10	73.9
rs:WP_038312524	DNA topoisomerase I [bacterium YEK0313].	24.31	547	320	23	4	505	1	498	3e-10	73.9
tr:A0A0E1QH36_CLOBO	SubName: Full=Putative DNA topoisomerase I {ECO:0000313|EMBL:BAQ14121.1};	23.39	543	335	18	7	517	10	503	3e-10	73.6
rs:WP_042744585	topoisomerase I, partial [Oenococcus oeni].	29.57	230	134	10	295	508	1	218	3e-10	70.5
rs:XP_009353380	PREDICTED: uncharacterized protein LOC103944634 [Pyrus x bretschneideri].	24.86	527	286	22	36	505	376	849	3e-10	73.9
rs:WP_043743329	DNA topoisomerase I [Magnetospirillum magneticum].	24.44	536	325	22	4	505	1	490	3e-10	73.9
rs:WP_043102403	DNA topoisomerase I [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	3e-10	73.9
rs:WP_046574015	DNA topoisomerase I [Spirosoma radiotolerans].	23.79	433	263	13	7	431	6	379	3e-10	73.9
rs:WP_009716793	DNA topoisomerase I [Streptomyces himastatinicus].	21.82	559	330	20	7	505	16	527	3e-10	73.9
rs:WP_033987437	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.20	572	348	18	7	541	6	517	3e-10	73.9
tr:Q7V627_PROMM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.17	449	266	17	101	505	102	524	3e-10	73.9
rs:WP_039700276	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	3e-10	73.6
rs:WP_022092241	DNA topoisomerase I [Firmicutes bacterium CAG:536].	25.86	522	310	21	7	504	6	474	3e-10	73.6
tr:H2WE23_CAEJA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.00	475	310	17	88	546	92	531	3e-10	73.6
rs:WP_022005438	GTP-sensing transcriptional pleiotropic repressor CodY [Firmicutes bacterium CAG:194].	24.78	448	272	20	93	504	63	481	3e-10	73.6
rs:WP_037089087	DNA topoisomerase I [Rhizobium sp. H41].	23.77	551	315	21	4	505	1	495	3e-10	73.9
rs:WP_024278932	DNA topoisomerase I [Xanthobacter sp. 126].	24.55	554	320	24	4	510	1	503	3e-10	73.9
rs:WP_014431876	DNA topoisomerase I [Caldilinea aerophila].	22.79	623	353	25	7	579	6	550	3e-10	73.9
tr:Q2W9I9_MAGSA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.44	536	325	22	4	505	3	492	3e-10	73.9
rs:WP_038845444	DNA topoisomerase I, partial [Campylobacter coli].	24.79	359	217	14	7	355	6	321	3e-10	72.0
rs:WP_006378418	DNA topoisomerase I [Streptomyces turgidiscabies].	22.92	554	329	20	7	505	15	525	3e-10	73.9
rs:WP_034915031	DNA topoisomerase III, partial [Candidatus Accumulibacter sp. BA-91].	32.04	181	111	6	7	184	6	177	3e-10	70.1
rs:WP_022295489	DNA topoisomerase [Firmicutes bacterium CAG:272].	23.74	535	317	22	7	505	5	484	3e-10	73.6
rs:WP_017626847	DNA topoisomerase I [Nocardiopsis chromatogenes].	23.29	554	328	23	7	505	26	537	3e-10	73.9
rs:WP_019503055	hypothetical protein [Pseudanabaena sp. PCC 6802].	23.11	528	323	16	89	583	72	549	3e-10	73.9
rs:WP_034078458	DNA topoisomerase I [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	3e-10	73.6
rs:WP_013264520	DNA topoisomerase I [Prevotella melaninogenica].	25.05	531	305	21	7	505	6	475	3e-10	73.6
rs:WP_027408673	DNA topoisomerase I [Anoxybacillus tepidamans].	23.93	422	269	14	112	504	82	480	3e-10	73.6
rs:WP_011141022	DNA topoisomerase I [Gloeobacter violaceus].	22.84	543	320	18	7	505	5	492	3e-10	73.6
rs:WP_033977639	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	3e-10	73.6
rs:WP_018332835	hypothetical protein [Actinomycetospora chiangmaiensis].	24.24	557	322	26	7	505	71	585	3e-10	73.9
rs:WP_018463724	DNA topoisomerase I [Prevotella paludivivens].	23.83	533	304	20	7	505	6	470	3e-10	73.6
rs:WP_025928114	DNA topoisomerase I [Prochlorococcus sp. scB243_495G23].	24.90	510	304	19	101	579	85	546	3e-10	73.6
tr:D4KTF6_9FIRM	SubName: Full=Draft genome {ECO:0000313|EMBL:CBL10158.1};	30.59	170	108	5	7	174	4	165	3e-10	69.7
tr:F9GUB0_HAEHA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.32	549	329	23	3	505	8	510	3e-10	73.6
rs:WP_025736321	DNA topoisomerase I [Mycobacterium genavense].	24.63	467	287	15	86	504	84	533	3e-10	73.6
tr:A0A0C7BNT0_9FUNG	SubName: Full=RMATCC62417_08376 protein {ECO:0000313|EMBL:CEG72895.1};	23.42	521	345	20	7	498	8	503	3e-10	73.6
rs:WP_011784655	MULTISPECIES: topoisomerase I [Marinobacter].	22.88	424	289	14	99	505	108	510	3e-10	73.6
rs:WP_036921705	DNA topoisomerase I [Prevotella sp. ICM33].	25.05	531	305	21	7	505	6	475	3e-10	73.6
rs:WP_035767149	DNA topoisomerase I [Butyrivibrio sp. NC2002].	24.83	447	276	21	93	505	66	486	3e-10	73.6
rs:WP_033543929	DNA topoisomerase I [Planococcus sp. CAU13].	23.02	530	320	18	7	504	6	479	3e-10	73.6
rs:WP_022207783	DNA topoisomerase [Eubacterium sp. CAG:252].	24.67	531	311	26	7	504	6	480	3e-10	73.6
rs:WP_031471430	DNA topoisomerase I [[Clostridium] aminophilum].	23.98	442	276	17	97	504	67	482	3e-10	73.6
rs:WP_004687268	DNA topoisomerase I [Brucella neotomae].	24.96	557	314	26	4	510	1	503	3e-10	73.6
rs:WP_029872825	DNA topoisomerase I [Rhizobium leguminosarum].	25.11	470	268	22	97	510	65	506	3e-10	73.6
rs:WP_023792924	hypothetical protein [candidate division SR1 bacterium RAAC1_SR1_1].	23.36	518	318	19	7	504	6	464	3e-10	73.6
rs:WP_032883712	DNA topoisomerase I [Clostridium sporogenes].	24.18	546	327	20	7	517	6	499	3e-10	73.6
tr:G9EXY9_CLOSG	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.18	546	327	20	7	517	10	503	3e-10	73.6
rs:WP_028050570	DNA topoisomerase I [Cellulomonas sp. URHD0024].	23.42	555	330	20	7	505	8	523	3e-10	73.6
rs:WP_038123375	DNA topoisomerase I [Veillonella sp. ICM51a].	23.71	582	347	23	7	564	69	577	3e-10	73.6
rs:WP_025329888	DNA topoisomerase I [Snodgrassella alvi].	24.54	542	308	23	7	505	6	489	3e-10	73.6
tr:K1UJH0_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78335.1}; Flags: Fragment;	24.81	266	175	6	40	304	5	246	3e-10	71.6
rs:WP_029108391	DNA topoisomerase I [Mycobacterium sp. URHD0025].	24.22	512	302	17	86	550	81	553	3e-10	73.6
rs:WP_037900954	DNA topoisomerase I [Streptomyces sviceus].	22.94	558	324	23	7	505	15	525	3e-10	73.6
rs:WP_040109633	DNA topoisomerase I [Clostridium botulinum].	24.18	546	327	20	7	517	6	499	3e-10	73.6
rs:WP_041385137	DNA topoisomerase I [Prochlorococcus marinus].	25.17	449	266	17	101	505	85	507	3e-10	73.6
rs:WP_024671025	DNA topoisomerase I [Pseudomonas syringae].	22.88	459	304	14	69	505	75	505	3e-10	73.6
rs:WP_016625619	DNA topoisomerase I [Enterococcus faecalis].	25.24	527	313	20	7	504	7	481	3e-10	73.6
rs:WP_039246338	DNA topoisomerase I, partial [Clostridium haemolyticum].	29.35	201	112	5	112	304	33	211	3e-10	70.5
rs:WP_007553288	DNA topoisomerase I [Bartonella sp. DB5-6].	25.28	451	273	20	97	505	65	493	3e-10	73.6
rs:WP_039728455	MULTISPECIES: DNA topoisomerase I [Oscillatoriophycideae].	24.71	518	320	16	65	550	48	527	3e-10	73.6
rs:WP_044939746	DNA topoisomerase I [Blautia schinkii].	23.68	435	283	16	97	504	67	479	3e-10	73.6
rs:WP_007351952	topoisomerase I [Marinobacter sp. ELB17].	23.35	424	287	14	99	505	108	510	3e-10	73.6
rs:WP_025443358	DNA topoisomerase I [Campylobacter coli].	22.96	527	326	18	5	505	4	476	3e-10	73.2
rs:WP_018910698	DNA topoisomerase I [Prevotella veroralis].	24.90	526	310	22	7	504	6	474	3e-10	73.6
rs:WP_040458502	hypothetical protein, partial [Holospora obtusa].	25.11	450	279	19	97	506	65	496	3e-10	73.6
rs:WP_046640510	DNA topoisomerase I [Neorhizobium galegae].	23.37	552	316	24	4	505	1	495	3e-10	73.6
tr:A0A0A8RCV9_PSEAI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.34	488	321	13	69	541	73	517	3e-10	73.6
rs:WP_026627609	DNA topoisomerase I [Dysgonomonas capnocytophagoides].	22.54	519	329	16	7	505	6	471	3e-10	73.6
rs:WP_030972245	DNA topoisomerase I [Streptomyces sp. NRRL S-1824].	22.72	559	326	22	7	505	15	527	3e-10	73.6
rs:WP_046635455	DNA topoisomerase I [Neorhizobium galegae].	23.37	552	316	24	4	505	1	495	3e-10	73.6
rs:WP_017274264	DNA topoisomerase I [Sinorhizobium meliloti].	23.65	554	307	25	4	505	1	490	3e-10	73.6
rs:WP_025746457	DNA topoisomerase I [Caldicoprobacter oshimai].	23.17	587	329	24	7	553	6	510	3e-10	73.6
tr:J9H515_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJX08960.1};	23.03	534	318	18	1	505	1	470	3e-10	73.6
rs:WP_022388599	DNA topoisomerase [Ruminococcus obeum CAG:39].	21.66	531	326	22	7	504	6	479	3e-10	73.2
tr:A0A061RF57_9CHLO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.66	634	359	25	5	586	56	616	3e-10	73.6
tr:K2A4U6_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.41	463	276	16	91	504	59	496	3e-10	73.2
rs:WP_009014722	MULTISPECIES: DNA topoisomerase I [Acidaminococcus].	24.40	586	341	26	7	564	5	516	4e-10	73.6
rs:WP_016459514	DNA topoisomerase I [Acidaminococcus sp. HPA0509].	24.23	586	342	25	7	564	5	516	4e-10	73.6
rs:WP_027720616	DNA topoisomerase I [Desulfovibrio zosterae].	23.57	543	317	21	7	510	6	489	4e-10	73.6
rs:WP_034672551	DNA topoisomerase I [Chryseobacterium formosense].	23.24	525	309	24	7	504	6	463	4e-10	73.6
rs:WP_007209321	topoisomerase [Enterococcus italicus].	36.44	118	65	5	5	118	3	114	4e-10	68.9
rs:WP_030495830	DNA topoisomerase I [Microtetraspora glauca].	23.26	559	321	22	7	505	15	525	4e-10	73.6
tr:C7GH19_9FIRM	SubName: Full=DNA topoisomerase III family protein {ECO:0000313|EMBL:EEU98885.1};	26.56	192	118	5	375	550	2	186	4e-10	72.0
tr:A0A090Q335_9FLAO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	31.15	244	133	11	102	336	73	290	4e-10	72.0
tr:A0A0A1NEC9_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.42	521	345	20	7	498	8	503	4e-10	73.6
rs:WP_044330152	DNA topoisomerase I [Haemophilus influenzae].	23.32	549	329	24	3	505	2	504	4e-10	73.6
rs:WP_010216795	topoisomerase I [Pseudomonas syringae group genomosp. 3].	22.96	453	311	12	69	505	75	505	4e-10	73.6
rs:WP_034973169	DNA topoisomerase I [Epilithonimonas lactis].	22.80	522	315	22	7	504	6	463	4e-10	73.6
rs:WP_013951507	DNA topoisomerase I [Candidatus Midichloria mitochondrii].	24.74	473	296	18	80	510	46	500	4e-10	73.6
rs:WP_008274156	DNA topoisomerase I [Cyanothece sp. CCY0110].	24.89	470	281	18	91	512	74	519	4e-10	73.6
rs:WP_022925447	DNA topoisomerase I [Serinicoccus marinus].	23.45	563	322	21	7	505	8	525	4e-10	73.6
rs:WP_005619258	DNA topoisomerase I [Pseudomonas avellanae].	22.74	453	312	12	69	505	75	505	4e-10	73.6
tr:A0A077XJG7_PLABA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	28.63	262	145	13	282	531	342	573	4e-10	73.2
rs:WP_032828011	DNA topoisomerase I [Haemophilus haemolyticus].	22.95	549	331	23	3	505	2	504	4e-10	73.6
rs:WP_045866076	DNA topoisomerase I [Streptomyces sp. WMMB 714].	23.68	549	331	20	7	505	15	525	4e-10	73.6
tr:E6MQ03_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.76	517	317	18	7	504	23	486	4e-10	73.2
rs:WP_005427273	DNA topoisomerase I [[Ruminococcus] obeum].	21.66	531	326	22	7	504	6	479	4e-10	73.2
tr:W0W4P1_ZYGBA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.50	600	357	25	7	546	3	560	4e-10	73.2
rs:WP_044513401	DNA topoisomerase I [Hymenobacter sp. DG25B].	21.77	519	331	17	7	505	6	469	4e-10	73.2
tr:S5VWG9_ENTFC	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AGS75352.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AGS75352.1};	32.47	154	96	3	417	563	2	154	4e-10	71.6
rs:WP_031656455	DNA topoisomerase I [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	4e-10	73.6
rs:WP_032494176	topoisomerase I, partial [Enterococcus faecium].	37.29	118	64	5	5	118	3	114	4e-10	68.6
tr:B5HVG2_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.12	558	323	23	7	505	28	538	4e-10	73.6
tr:W6TE90_HOLOB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.11	450	279	19	97	506	65	496	4e-10	73.6
rs:WP_022292352	DNA topoisomerase [Staphylococcus sp. CAG:324].	25.98	435	255	18	107	504	78	482	4e-10	73.2
rs:WP_028587743	DNA topoisomerase I [Desulfocurvus vexinensis].	23.86	591	340	24	3	562	2	513	4e-10	73.2
rs:WP_040092879	DNA topoisomerase I [Spiroplasma poulsonii].	22.33	524	326	18	5	504	4	470	4e-10	73.2
rs:WP_014857204	DNA topoisomerase I [Melioribacter roseus].	23.47	571	329	21	7	514	6	531	4e-10	73.2
tr:A0A0B0HQ32_9BACI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	32.48	157	93	6	295	443	2	153	4e-10	69.7
tr:C0D9F9_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.20	444	289	15	93	504	69	492	4e-10	73.2
rs:WP_034052320	DNA topoisomerase I [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	4e-10	73.2
tr:S8D4C5_9LAMI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.43	589	345	21	36	567	29	568	4e-10	73.2
rs:WP_014397849	DNA topoisomerase I [Corallococcus coralloides].	22.40	567	328	20	7	516	86	597	4e-10	73.2
rs:WP_034024827	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	4e-10	73.2
rs:WP_023114523	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	4e-10	73.2
rs:WP_012200735	DNA topoisomerase I [Lachnoclostridium phytofermentans].	22.93	532	320	23	7	504	6	481	4e-10	73.2
rs:WP_004848998	MULTISPECIES: DNA topoisomerase I [Coprococcus].	22.76	536	315	23	7	504	6	480	4e-10	73.2
rs:WP_024708367	DNA topoisomerase I [Martelella sp. AD-3].	23.60	555	327	24	4	510	1	506	4e-10	73.2
tr:J6XCY2_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJX43826.1}; Flags: Fragment;	31.58	152	95	5	56	205	1	145	4e-10	69.3
rs:WP_028799128	DNA topoisomerase I [Streptomyces sp. 142MFCol3.1].	23.21	560	320	24	7	505	15	525	4e-10	73.2
rs:WP_034069888	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	4e-10	73.2
rs:WP_012075146	topoisomerase I [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	4e-10	73.2
rs:WP_005765057	MULTISPECIES: topoisomerase I [Pseudomonas syringae group].	22.96	453	311	12	69	505	75	505	4e-10	73.2
tr:F9QAQ0_9PAST	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.29	457	282	18	79	505	6	428	4e-10	73.2
rs:WP_029355145	DNA topoisomerase I [Bosea sp. 117].	23.42	555	325	22	4	510	1	503	4e-10	73.2
rs:WP_045108467	DNA topoisomerase I [Pseudomonas sp. HMSC05H02].	22.34	488	321	13	69	541	73	517	4e-10	73.2
rs:WP_010278379	DNA topoisomerase I [Leuconostoc pseudomesenteroides].	24.66	446	273	19	93	505	56	471	4e-10	73.2
rs:WP_037360135	DNA topoisomerase I [Schleiferia thermophila].	24.70	417	266	13	107	504	77	464	4e-10	73.2
rs:WP_010705324	DNA topoisomerase I [Bartonella vinsonii].	23.96	551	312	27	4	505	1	493	4e-10	73.2
rs:WP_022141914	DNA topoisomerase [Clostridium sp. CAG:230].	22.73	528	325	23	7	504	6	480	4e-10	73.2
rs:WP_034001363	DNA topoisomerase I [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	4e-10	73.2
rs:WP_034025524	DNA topoisomerase I [Pseudomonas aeruginosa].	22.54	488	320	14	69	541	73	517	4e-10	73.2
rs:WP_011104593	DNA topoisomerase I [Pseudomonas syringae group genomosp. 3].	22.96	453	311	12	69	505	75	505	4e-10	73.2
rs:WP_045089368	DNA topoisomerase I [Porphyromonadaceae bacterium ING2-E5B].	24.42	520	313	19	7	504	6	467	4e-10	73.2
rs:WP_044390317	DNA topoisomerase I [Pseudomonas syringae group genomosp. 3].	22.96	453	311	12	69	505	75	505	4e-10	73.2
rs:WP_022108248	DNA topoisomerase [Clostridium sp. CAG:138].	22.15	578	351	22	5	553	4	511	4e-10	73.2
rs:WP_043614100	DNA topoisomerase I [Ensifer sp. ZNC0028].	23.95	547	319	22	4	505	1	495	4e-10	73.2
rs:WP_005612814	DNA topoisomerase I [Ruminococcus lactaris].	24.32	444	279	16	93	504	63	481	4e-10	73.2
rs:WP_024999384	DNA topoisomerase I [Prevotella falsenii].	25.58	430	260	13	7	431	6	380	4e-10	73.2
rs:WP_024857897	DNA topoisomerase I [Ruminococcus albus].	24.94	417	260	16	107	495	76	467	4e-10	73.2
tr:X8F2C5_MYCUL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.31	469	288	17	86	505	27	477	4e-10	72.8
rs:WP_044079149	DNA topoisomerase I [Prevotella salivae].	24.76	517	317	18	7	504	6	469	4e-10	73.2
tr:K0JTU7_SACES	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.35	561	336	25	7	510	44	567	4e-10	73.2
rs:WP_026668681	DNA topoisomerase I [Butyrivibrio sp. AE3009].	23.78	534	314	26	7	504	1	477	4e-10	73.2
rs:WP_042776260	hypothetical protein [Vibrio parahaemolyticus].	26.98	252	141	11	8	231	5	241	4e-10	70.9
rs:WP_024281948	DNA topoisomerase I [Algoriphagus marincola].	22.58	527	322	17	3	505	2	466	5e-10	73.2
tr:A0A0C7C5P2_9FUNG	SubName: Full=RMATCC62417_13354 protein {ECO:0000313|EMBL:CEG78805.1};	23.44	529	335	21	7	498	8	503	5e-10	73.2
rs:WP_009010972	DNA topoisomerase I [Prevotella sp. C561].	23.72	527	317	17	7	505	6	475	5e-10	73.2
rs:WP_006126427	MULTISPECIES: DNA topoisomerase I [Streptomyces].	22.86	560	324	22	7	505	15	527	5e-10	73.2
rs:WP_013231643	DNA topoisomerase I [Leuconostoc gelidum].	23.73	531	313	22	7	504	29	500	5e-10	73.2
rs:WP_034033495	DNA topoisomerase I [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	5e-10	73.2
sp:TOP1_PSEAE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	22.34	488	321	13	69	541	73	517	5e-10	73.2
rs:WP_015157793	DNA topoisomerase I [Chamaesiphon minutus].	22.37	617	364	20	5	579	3	546	5e-10	73.2
rs:WP_021736657	DNA topoisomerase I [Acidaminococcus sp. BV3L6].	24.10	585	344	24	7	564	5	516	5e-10	73.2
rs:WP_007789732	DNA topoisomerase I [Rhizobium sp. CF122].	27.27	451	246	21	107	505	75	495	5e-10	73.2
rs:WP_033952254	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	5e-10	73.2
rs:WP_034084293	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	5e-10	73.2
rs:WP_031806109	DNA topoisomerase I [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	5e-10	73.2
rs:WP_015486301	DNA topoisomerase I [Thalassolituus oleivorans].	23.09	459	304	15	69	505	79	510	5e-10	73.2
rs:WP_046870408	DNA topoisomerase I [Clostridium sporogenes].	24.21	541	323	20	7	512	6	494	5e-10	72.8
rs:WP_035287277	DNA topoisomerase I [Actinokineospora sp. EG49].	24.22	574	315	21	7	510	19	542	5e-10	73.2
rs:WP_015918923	DNA topoisomerase I [Thermotoga neapolitana].	23.72	527	303	23	7	504	8	464	5e-10	72.8
rs:WP_022204968	DNA topoisomerase [Eubacterium sp. CAG:248].	24.81	536	304	27	7	504	6	480	5e-10	72.8
tr:D7IEM3_9BACE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.23	444	271	15	89	504	23	433	5e-10	72.8
tr:F3CEV4_PSESG	SubName: Full=Orf50 {ECO:0000313|EMBL:EGH17796.1}; Flags: Fragment;	31.43	140	82	2	366	491	2	141	5e-10	68.9
rs:WP_018108870	DNA topoisomerase I [Bacteroides propionicifaciens].	23.05	525	318	20	7	504	6	471	5e-10	73.2
rs:WP_031685624	DNA topoisomerase I [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	5e-10	73.2
tr:V6M7K9_9EUKA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.18	524	348	21	5	498	3	491	5e-10	73.2
gpu:KM982401_221	topoisomerase I [Acanthamoeba polyphaga mimivirus]	26.60	406	218	18	7	389	5	353	5e-10	73.2
rs:WP_007251279	topoisomerase I [Pseudomonas syringae group genomosp. 3].	22.98	457	306	13	69	505	75	505	5e-10	73.2
rs:WP_035263470	DNA topoisomerase I, partial [Desulfonatronum lacustre].	24.78	448	282	16	88	506	58	479	5e-10	72.8
tr:A0A0C7NVR5_9THEM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.58	530	309	23	7	504	43	508	5e-10	72.8
rs:WP_033892277	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	28	472	5e-10	73.2
rs:WP_033443240	DNA topoisomerase I, partial [Saccharothrix sp. NRRL B-16314].	23.56	573	327	26	7	510	2	532	5e-10	73.2
rs:WP_036872957	DNA topoisomerase I [Prevotella buccalis].	23.92	581	329	24	7	548	6	512	5e-10	72.8
rs:WP_033996124	DNA topoisomerase I [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	5e-10	73.2
rs:WP_033178772	DNA topoisomerase I [Mycoplasma anseris].	23.56	433	278	16	93	504	65	465	5e-10	72.8
rs:WP_028892457	DNA topoisomerase I [Tenacibaculum sp. 47A_GOM-205m].	25.00	528	296	25	7	504	6	463	5e-10	73.2
rs:WP_010011264	topoisomerase I [Lactobacillus coryniformis].	22.70	445	301	14	7	427	6	431	5e-10	72.8
rs:WP_015309699	DNA topoisomerase I [Mycobacterium smegmatis].	23.57	471	288	16	86	504	82	532	5e-10	73.2
rs:WP_031804255	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	5e-10	72.4
rs:WP_023168138	DNA topoisomerase III, partial [Salmonella enterica].	27.33	150	102	2	408	552	2	149	5e-10	70.1
rs:WP_006008809	DNA topoisomerase I [Desulfovibrio piger].	24.84	459	284	16	80	505	48	478	5e-10	72.8
tr:D3R3C1_BIFAB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.12	556	331	20	7	505	19	529	5e-10	73.2
rs:WP_034558155	topoisomerase [Carnobacterium gallinarum].	37.29	118	64	5	5	118	3	114	5e-10	68.6
tr:A0A087Q9T5_LACGS	SubName: Full=Dna topoIsomerase i (Omega-protein) {ECO:0000313|EMBL:KFL96388.1};	26.67	345	209	14	7	335	5	321	5e-10	73.2
rs:WP_009104432	DNA topoisomerase I [Treponema sp. JC4].	23.08	533	318	20	5	504	13	486	5e-10	72.8
rs:WP_037004128	hypothetical protein, partial [Pseudomonas fuscovaginae].	37.00	100	58	3	307	402	2	100	5e-10	67.8
rs:XP_010750977	PREDICTED: DNA topoisomerase 3-beta-1 [Larimichthys crocea].	25.35	284	166	14	283	553	290	540	5e-10	72.8
rs:WP_026641743	DNA topoisomerase I [Bifidobacterium tsurumiense].	22.28	579	317	22	7	505	8	533	5e-10	73.2
rs:WP_026385425	DNA topoisomerase I [Acidaminococcus intestini].	25.72	486	288	21	107	564	76	516	5e-10	72.8
rs:WP_011651394	DNA topoisomerase I [Rhizobium leguminosarum].	25.11	470	268	22	97	510	65	506	5e-10	72.8
rs:WP_010148231	DNA topoisomerase I [Serinicoccus profundi].	23.94	564	318	21	7	505	8	525	5e-10	73.2
rs:WP_028962263	DNA topoisomerase I [Sulfobacillus thermosulfidooxidans].	23.23	538	319	20	7	504	8	491	5e-10	72.8
sp:TOP3B_ARATH	RecName: Full=DNA topoisomerase 3-beta; EC=5.99.1.2;	23.22	633	401	28	7	583	9	612	5e-10	72.8
rs:WP_035425215	hypothetical protein, partial [Lactobacillus gasseri].	26.96	345	208	15	7	335	5	321	5e-10	72.8
tr:A0A0A9J692_ARUDO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.49	459	275	16	97	505	16	457	5e-10	72.8
rs:WP_010801879	MULTISPECIES: DNA topoisomerase I [Parabacteroides].	23.35	591	357	23	7	564	6	533	5e-10	72.8
rs:WP_029296505	DNA topoisomerase I [Chryseobacterium hispalense].	21.84	522	320	21	7	504	6	463	5e-10	72.8
rs:WP_009388753	DNA topoisomerase I [Capnocytophaga sp. oral taxon 329].	23.89	519	313	21	7	504	6	463	5e-10	72.8
rs:WP_035058842	DNA topoisomerase I [Andreprevotia chitinilytica].	26.17	447	266	15	107	510	77	502	6e-10	72.8
rs:WP_046872095	hypothetical protein [Pediococcus damnosus].	31.08	148	83	4	200	339	1	137	6e-10	68.9
rs:WP_010530648	DNA topoisomerase I [Lentibacillus jeotgali].	25.12	426	272	15	107	505	77	482	6e-10	72.8
rs:WP_014210569	DNA topoisomerase I [Mycobacterium rhodesiae].	23.28	597	345	22	7	550	10	546	6e-10	72.8
tr:F8XMJ0_9GAMM	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.72	311	186	12	57	350	14	296	6e-10	71.2
rs:WP_012789627	DNA topoisomerase I [Chitinophaga pinensis].	23.83	428	262	15	7	426	6	377	6e-10	72.8
rs:WP_032524149	DNA topoisomerase I [Prochlorococcus marinus].	24.76	513	301	18	101	579	85	546	6e-10	72.8
rs:WP_029038870	DNA topoisomerase I [Salinimicrobium xinjiangense].	25.40	433	252	15	7	430	6	376	6e-10	72.8
rs:WP_021968589	DNA topoisomerase [Mycoplasma sp. CAG:956].	25.50	451	280	20	80	504	53	473	6e-10	72.8
rs:WP_003041712	DNA topoisomerase I [Francisella tularensis].	22.43	544	323	20	7	505	6	495	6e-10	72.8
rs:WP_045088522	DNA topoisomerase I [Defluviitoga tunisiensis].	23.54	531	310	23	7	505	14	480	6e-10	72.8
rs:WP_043299032	DNA topoisomerase I [Pseudomonas sp. HMP271].	22.10	525	355	16	7	505	6	502	6e-10	72.8
tr:K1V3R2_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC78506.1}; Flags: Fragment;	31.46	178	112	5	7	182	4	173	6e-10	69.3
rs:WP_034508708	DNA topoisomerase I [Agrobacterium rhizogenes].	25.82	457	262	21	107	510	75	507	6e-10	72.8
rs:WP_044385305	DNA topoisomerase I [Marinobacter excellens].	23.06	425	287	15	99	505	108	510	6e-10	72.8
rs:WP_027586796	DNA topoisomerase I [Propionibacterium thoenii].	23.29	571	320	25	5	505	6	528	6e-10	72.8
rs:WP_021971636	DNA topoisomerase [Bacteroides sp. CAG:1076].	22.93	519	320	20	7	504	6	465	6e-10	72.8
tr:F3R6F7_ENTFL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.45	319	202	10	213	504	1	307	6e-10	72.4
tr:A0A068RFI3_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.69	236	147	9	275	498	275	496	6e-10	72.4
rs:WP_008200254	DNA topoisomerase I [Algoriphagus machipongonensis].	25.51	345	226	8	89	430	59	375	6e-10	72.8
tr:U6PAL2_HAECO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.90	589	374	25	2	553	38	577	6e-10	72.8
rs:WP_041315862	DNA topoisomerase I, partial [Saccharothrix espanaensis].	23.35	561	336	25	7	510	2	525	6e-10	72.8
tr:Q895L4_CLOTE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.70	443	280	16	93	504	65	480	6e-10	72.4
rs:WP_042215902	DNA topoisomerase I [Lysinimicrobium mangrovi].	22.66	556	332	19	7	505	6	520	6e-10	72.8
rs:WP_046369750	DNA topoisomerase I [Flavihumibacter petaseus].	24.77	428	265	14	7	430	6	380	6e-10	72.8
rs:WP_019682694	topoisomerase I, partial [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	6e-10	72.8
tr:A0A090RLB9_9VIBR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.15	410	268	15	114	505	2	386	6e-10	72.4
rs:WP_007655144	DNA topoisomerase I [Parabacteroides goldsteinii].	23.65	520	316	19	7	504	6	466	6e-10	72.8
rs:WP_037215870	DNA topoisomerase I [Rhizobium sp. IBUN].	27.06	462	249	22	107	510	75	506	6e-10	72.8
rs:WP_000108744	MULTISPECIES: topoisomerase [Bacilli].	37.29	118	64	5	5	118	3	114	6e-10	68.2
tr:J9FSD0_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EJW97866.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EJW97866.1}; Flags: Fragment;	28.05	164	111	4	374	534	27	186	6e-10	70.1
rs:WP_038025549	DNA topoisomerase I [Tenacibaculum maritimum].	24.62	520	308	20	7	504	6	463	6e-10	72.8
rs:WP_002730363	DNA topoisomerase I [Phaeospirillum molischianum].	24.77	533	321	22	7	505	4	490	6e-10	72.8
rs:WP_039104346	DNA topoisomerase I [Frischella perrara].	23.75	539	329	19	7	505	6	502	7e-10	72.8
rs:WP_029558610	DNA topoisomerase I [Xanthobacter sp. 91].	24.55	554	320	24	4	510	1	503	7e-10	72.8
rs:WP_003608118	DNA topoisomerase I [Weissella confusa].	22.20	473	276	15	7	432	6	433	7e-10	72.4
rs:WP_022153888	DNA topoisomerase [Firmicutes bacterium CAG:65].	23.82	487	315	22	47	504	21	480	7e-10	72.4
tr:J9Z2K6_9PROT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.32	579	339	24	7	552	4	510	7e-10	72.8
rs:WP_003033127	DNA topoisomerase I [Francisella tularensis].	22.43	544	323	20	7	505	6	495	7e-10	72.4
rs:WP_012429273	DNA topoisomerase I [Francisella tularensis].	22.43	544	323	21	7	505	6	495	7e-10	72.4
rs:WP_036864134	DNA topoisomerase I [Prevotella bivia].	23.84	537	305	22	7	505	6	476	7e-10	72.4
rs:WP_028848545	DNA topoisomerase I [Thermocrispum agreste].	22.22	558	333	19	7	505	17	532	7e-10	72.8
rs:WP_004859900	DNA topoisomerase I [Bartonella taylorii].	24.36	546	310	27	7	505	4	493	7e-10	72.4
rs:WP_039261035	DNA topoisomerase I [Clostridium tetani].	24.55	444	275	17	93	504	63	478	7e-10	72.4
rs:WP_034962999	DNA topoisomerase I [Epilithonimonas sp. FH1].	22.61	522	316	23	7	504	6	463	7e-10	72.4
rs:WP_037476183	DNA topoisomerase I [Snodgrassella alvi].	24.63	540	310	23	7	505	6	489	7e-10	72.4
tr:A0A099VQ59_9HELI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	27.59	261	156	9	269	505	34	285	7e-10	72.0
tr:J3E777_9VIRU	SubName: Full=Topoisomerase I (Bacterial type) {ECO:0000313|EMBL:EJN40679.1};	26.35	406	219	17	7	389	5	353	7e-10	72.4
rs:WP_035307621	DNA topoisomerase I [Clostridium sp. HMP27].	23.76	526	322	19	7	504	6	480	7e-10	72.4
rs:WP_004070358	DNA topoisomerase I [Clostridium sp. ASF502].	22.41	531	324	23	7	504	6	481	7e-10	72.4
tr:L9PZY6_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELX68407.1};	30.18	169	103	4	375	531	1	166	7e-10	70.9
rs:WP_004336816	DNA topoisomerase I [Prevotella bivia].	23.84	537	305	22	7	505	6	476	7e-10	72.4
rs:WP_027115901	DNA topoisomerase I [Lachnospiraceae bacterium P6B14].	24.16	505	312	21	36	504	10	479	7e-10	72.4
rs:WP_031488882	DNA topoisomerase I [Ureaplasma canigenitalium].	23.30	545	328	20	1	504	1	496	7e-10	72.4
tr:A4N5H6_HAEIF	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.12	452	289	18	79	505	82	504	7e-10	72.4
tr:W5Q119_SHEEP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.91	301	183	16	216	498	227	505	7e-10	72.4
rs:WP_042909648	DNA topoisomerase I [Mycobacterium intracellulare].	24.52	469	285	17	86	504	85	534	7e-10	72.4
rs:WP_029504183	DNA topoisomerase I [Lachnoclostridium phytofermentans].	22.41	540	313	24	7	504	6	481	7e-10	72.4
rs:WP_037984289	DNA topoisomerase I [Tannerella sp. oral taxon BU063].	23.97	534	300	22	7	504	6	469	7e-10	72.4
rs:WP_023345728	DNA topoisomerase I [Firmicutes bacterium ASF500].	22.10	629	383	25	7	599	8	565	7e-10	72.4
tr:F3FN41_PSESX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH31627.1}; Flags: Fragment;	35.24	105	60	3	8	112	5	101	7e-10	67.4
rs:WP_024734480	DNA topoisomerase I [Clostridiales bacterium VE202-15].	23.20	444	289	15	93	504	63	486	7e-10	72.4
rs:WP_042619786	DNA topoisomerase I [Agrobacterium tumefaciens].	23.77	547	314	24	7	505	5	496	7e-10	72.4
rs:WP_042674119	DNA topoisomerase, partial [Methylobacterium sp. B34].	24.22	223	154	7	29	243	20	235	8e-10	69.7
rs:WP_037392358	DNA topoisomerase I [Snodgrassella alvi].	24.63	540	310	23	7	505	6	489	8e-10	72.4
rs:WP_040278328	DNA topoisomerase I [Psychroserpens damuponensis].	26.54	422	253	17	106	504	76	463	8e-10	72.4
rs:WP_020308961	DNA topoisomerase I [Pseudomonas stutzeri].	24.88	422	269	13	107	505	75	471	8e-10	72.4
rs:WP_031630901	DNA topoisomerase 1 [Pseudomonas aeruginosa].	22.34	488	321	13	69	541	73	517	8e-10	72.4
rs:WP_028121072	DNA topoisomerase I [Epilithonimonas tenax].	22.61	522	316	23	7	504	6	463	8e-10	72.4
rs:WP_011890947	DNA topoisomerase I [Chlorobium phaeovibrioides].	23.71	561	326	25	5	515	14	522	8e-10	72.4
rs:XP_728858	DNA topoisomerase III [Plasmodium yoelii yoelii 17XNL].	28.63	262	145	13	282	531	344	575	8e-10	72.4
rs:WP_035124882	DNA topoisomerase I [Clostridium tetani].	23.70	443	280	16	93	504	63	478	8e-10	72.4
rs:WP_006727604	DNA topoisomerase I [Agrobacterium albertimagni].	25.73	443	264	20	107	505	75	496	8e-10	72.4
rs:WP_009347727	DNA topoisomerase I [Alloprevotella rava].	23.44	529	306	23	7	505	8	467	8e-10	72.4
rs:WP_039171001	DNA topoisomerase I [Bifidobacterium pseudolongum].	20.89	560	331	19	7	505	8	516	8e-10	72.4
rs:WP_004219309	DNA topoisomerase I [Bifidobacterium animalis].	22.12	556	331	20	7	505	8	518	8e-10	72.4
rs:WP_013499649	DNA topoisomerase I [Ruminococcus albus].	24.70	417	261	16	107	495	76	467	8e-10	72.4
rs:WP_023058511	MULTISPECIES: DNA topoisomerase I [Prevotella].	23.70	578	334	23	7	548	6	512	8e-10	72.4
rs:WP_006282731	DNA topoisomerase I [Prevotella bryantii].	23.50	532	304	21	7	504	6	468	8e-10	72.4
rs:WP_011975123	DNA topoisomerase I [Sinorhizobium medicae].	23.65	554	314	23	3	505	20	515	8e-10	72.4
rs:WP_026328586	DNA topoisomerase I [Streptomyces sulphureus].	23.90	456	282	17	97	505	90	527	8e-10	72.4
rs:WP_024846942	DNA topoisomerase I [Aminobacter sp. J41].	23.22	547	320	24	4	505	1	492	8e-10	72.4
rs:WP_027962277	DNA topoisomerase I [Halomonas halodenitrificans].	22.35	434	299	12	88	505	99	510	8e-10	72.4
rs:WP_038010604	DNA topoisomerase I [Tannerella sp. oral taxon BU063].	23.98	538	295	24	7	504	6	469	8e-10	72.4
rs:WP_043413119	DNA topoisomerase I [Mycobacterium rufum].	23.40	470	290	15	86	504	82	532	8e-10	72.4
rs:XP_004202179	Piso0_001663 [Millerozyma farinosa CBS 7064].	22.55	581	359	21	7	547	3	532	8e-10	72.0
rs:WP_020409425	topoisomerase I [Hahella ganghwensis].	22.75	422	290	14	99	505	108	508	8e-10	72.4
rs:WP_020122616	DNA topoisomerase I [Streptomyces canus].	23.60	555	324	24	7	505	15	525	8e-10	72.4
rs:WP_022542520	DNA topoisomerase I [Bifidobacterium animalis].	22.12	556	331	20	7	505	8	518	8e-10	72.4
rs:WP_027449291	DNA topoisomerase I [Prevotella brevis].	23.94	447	282	15	88	504	56	474	8e-10	72.4
rs:WP_003038456	DNA topoisomerase I [Francisella tularensis].	22.43	544	323	20	7	505	6	495	8e-10	72.4
rs:WP_018857025	DNA topoisomerase I [Rhizobium sp. 42MFCr.1].	27.06	462	249	22	107	510	75	506	8e-10	72.4
rs:WP_011132072	DNA topoisomerase I [Prochlorococcus marinus].	24.94	441	277	15	101	505	85	507	8e-10	72.4
rs:WP_012504231	topoisomerase I [Candidatus Phytoplasma mali].	25.72	451	273	18	80	504	50	464	8e-10	72.0
rs:WP_041485569	hypothetical protein, partial [alpha proteobacterium HIMB59].	23.32	579	339	24	7	552	4	510	8e-10	72.4
rs:WP_036953684	DNA topoisomerase I [Promicromonosporaceae bacterium W15].	22.50	600	355	19	7	550	8	553	8e-10	72.4
rs:WP_011580693	DNA topoisomerase I [Chelativorans sp. BNC1].	23.72	548	316	25	4	505	1	492	8e-10	72.4
rs:WP_036865838	DNA topoisomerase I [Prevotella bivia].	23.84	537	305	22	7	505	6	476	8e-10	72.4
rs:WP_022109808	DNA topoisomerase [Prevotella sp. CAG:604].	23.46	537	300	21	7	505	6	469	8e-10	72.4
rs:WP_014709083	DNA topoisomerase I [Prevotella intermedia].	23.48	528	317	18	7	505	6	475	8e-10	72.4
rs:WP_017304772	DNA topoisomerase I [Spirulina subsalsa].	25.29	522	291	19	91	568	74	540	8e-10	72.4
tr:K2AAC1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.66	541	321	18	7	505	4	494	9e-10	72.0
rs:WP_012700082	topoisomerase I [Azotobacter vinelandii].	21.67	540	344	17	5	505	4	503	9e-10	72.4
rs:WP_027641384	DNA topoisomerase I [[Clostridium] clostridioforme].	23.36	441	292	15	93	504	63	486	9e-10	72.0
rs:WP_020941373	DNA topoisomerase I [Streptomyces collinus].	22.94	558	324	23	7	505	15	525	9e-10	72.4
rs:WP_044658039	DNA topoisomerase I, partial [Propionibacterium freudenreichii].	25.46	381	231	15	80	430	65	422	9e-10	71.6
rs:WP_003017863	DNA topoisomerase I [Francisella tularensis].	22.43	544	323	20	7	505	6	495	9e-10	72.0
tr:A0A0D6E964_9GAMM	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:CEP35824.1};	22.35	452	314	13	69	505	80	509	9e-10	72.4
rs:WP_044628075	DNA topoisomerase I [Halomonas meridiana].	23.13	454	308	14	69	505	80	509	9e-10	72.4
rs:WP_040940167	hypothetical protein, partial [Prochloron didemni].	22.46	619	365	20	7	579	5	554	9e-10	72.4
rs:WP_026393154	DNA topoisomerase I [Acetobacterium dehalogenans].	25.00	424	269	15	107	504	77	477	9e-10	72.0
tr:T1CAM2_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD78318.1};	26.20	187	131	3	4	190	1	180	9e-10	69.3
rs:WP_025394120	DNA topoisomerase I [Rhizobium leguminosarum].	25.11	466	273	22	97	510	65	506	9e-10	72.4
rs:WP_003014690	DNA topoisomerase I [Francisella tularensis].	22.43	544	323	20	7	505	6	495	9e-10	72.0
rs:WP_013170872	DNA topoisomerase I [Arcanobacterium haemolyticum].	22.67	547	337	17	7	505	5	513	9e-10	72.4
rs:WP_027434871	DNA topoisomerase I [Lachnospiraceae bacterium AB2028].	25.22	448	278	20	93	505	63	488	9e-10	72.0
rs:WP_042991435	DNA topoisomerase III, partial [Bifidobacterium adolescentis].	28.26	230	148	6	7	232	4	220	9e-10	69.3
rs:WP_013751171	DNA topoisomerase I [Dokdonia sp. 4H-3-7-5].	25.14	537	306	24	7	512	6	477	9e-10	72.4
rs:WP_027942841	DNA topoisomerase I [Amycolatopsis taiwanensis].	22.49	547	343	19	7	505	22	535	9e-10	72.4
rs:WP_045921594	DNA topoisomerase I [Bifidobacterium coryneforme].	20.32	571	341	18	7	505	8	536	9e-10	72.4
rs:WP_032373213	topoisomerase I [Rhodococcus fascians].	23.88	448	275	17	7	425	6	416	9e-10	72.0
rs:WP_025068440	DNA topoisomerase, partial [Prevotella denticola].	27.81	169	105	4	376	531	26	190	9e-10	70.9
rs:WP_022523166	DNA topoisomerase 1 [Halomonas sp. A3H3].	22.35	452	314	13	69	505	80	509	9e-10	72.0
rs:WP_039325786	DNA topoisomerase I [Mycobacterium setense].	24.02	512	303	17	86	550	81	553	9e-10	72.4
tr:L8TXQ7_AGGAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.53	322	212	11	201	505	8	315	9e-10	72.0
rs:WP_013103076	MULTISPECIES: DNA topoisomerase I [Leuconostoc].	24.60	435	281	17	96	505	89	501	9e-10	72.0
rs:WP_030285364	DNA topoisomerase I [Streptomyces catenulae].	24.57	464	268	19	97	505	91	527	9e-10	72.4
rs:WP_002339153	hypothetical protein [Enterococcus faecium].	36.13	119	66	5	5	119	3	115	9e-10	67.4
rs:WP_035579838	DNA topoisomerase I [Halomonas sp. TG39a].	22.35	452	314	13	69	505	80	509	9e-10	72.0
tr:A0A078KLR4_9APIC	SubName: Full=DNA topoisomerase III, putative {ECO:0000313|EMBL:CDZ17700.1};	28.63	262	145	13	282	531	344	575	1e-09	72.0
rs:WP_003026515	DNA topoisomerase I [Francisella tularensis].	22.43	544	323	20	7	505	6	495	1e-09	72.0
rs:WP_006845568	DNA topoisomerase I [Weissella koreensis].	22.48	525	331	17	7	505	24	498	1e-09	72.0
rs:WP_032399748	topoisomerase I [Rhodococcus fascians].	23.88	448	275	17	7	425	6	416	1e-09	72.0
rs:WP_028000105	DNA topoisomerase I [Sinorhizobium arboris].	23.69	553	313	23	4	505	1	495	1e-09	72.0
rs:WP_032823063	DNA topoisomerase I, partial [Haemophilus influenzae].	23.67	452	291	18	79	505	82	504	1e-09	72.0
rs:WP_044126130	hypothetical protein [Vibrio cholerae].	24.62	459	286	19	75	495	37	473	1e-09	72.0
rs:WP_007568290	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.64	533	299	22	7	504	6	465	1e-09	72.0
rs:WP_016597622	topoisomerase I, partial [Yersinia pestis].	24.48	388	250	14	136	505	6	368	1e-09	72.0
rs:WP_039382418	DNA topoisomerase I [Mycobacterium setense].	24.02	512	303	17	86	550	81	553	1e-09	72.0
rs:WP_011741856	DNA topoisomerase I [Mycobacterium ulcerans].	24.31	469	288	17	86	505	88	538	1e-09	72.0
rs:WP_013739712	DNA topoisomerase I [Sphaerochaeta coccoides].	23.43	542	326	19	7	505	11	506	1e-09	72.0
rs:WP_040556917	DNA topoisomerase I [Prevotella nigrescens].	25.17	433	258	13	7	431	6	380	1e-09	72.0
rs:WP_045859928	DNA topoisomerase I [Alteromonadaceae bacterium Bs12].	21.74	437	298	12	88	505	99	510	1e-09	72.0
rs:WP_022835723	DNA topoisomerase I [Salisaeta longa].	24.18	546	301	22	91	579	75	564	1e-09	72.0
rs:WP_004363587	DNA topoisomerase I [Prevotella nigrescens].	25.17	433	258	13	7	431	6	380	1e-09	72.0
rs:WP_013291693	DNA topoisomerase I [Clostridium cellulovorans].	22.74	532	324	20	7	504	6	484	1e-09	72.0
rs:WP_022262390	DNA topoisomerase [Butyrivibrio sp. CAG:318].	23.88	469	291	17	93	531	63	495	1e-09	72.0
rs:WP_024759186	DNA topoisomerase I [Streptomyces exfoliatus].	23.93	560	316	22	7	505	15	525	1e-09	72.0
rs:WP_027764162	DNA topoisomerase I [Streptomyces sp. CNS606].	24.57	464	274	19	97	505	90	532	1e-09	72.0
rs:WP_013989151	DNA topoisomerase I [Weissella koreensis].	22.62	526	329	18	7	505	24	498	1e-09	72.0
tr:I0TDV4_9BACT	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EID33807.1};	27.78	198	122	5	5	191	3	190	1e-09	68.9
tr:A0A061P3Q6_9BACL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.78	518	330	18	93	581	33	509	1e-09	71.6
rs:WP_042827053	DNA topoisomerase I, partial [Xanthomonas axonopodis].	26.83	246	159	8	107	348	75	303	1e-09	70.1
gpu:CP011232_515	DNA topoisomerase I [Kosmotoga pacifica]	25.33	525	316	22	5	505	4	476	1e-09	72.0
rs:WP_034235967	DNA topoisomerase I [Actinomyces urogenitalis].	21.90	580	327	20	7	505	6	540	1e-09	72.0
rs:WP_040943789	DNA topoisomerase I [Prochloron didemni].	22.46	619	365	20	7	579	5	554	1e-09	72.0
rs:WP_046456236	DNA topoisomerase I [Leucobacter sp. Ag1].	23.57	560	327	23	7	505	8	527	1e-09	72.0
rs:WP_006548004	DNA topoisomerase I [Actinomyces urogenitalis].	21.90	580	327	20	7	505	6	540	1e-09	72.0
rs:WP_006698006	DNA topoisomerase I [Rhizobium lupini].	23.45	550	318	20	4	505	1	495	1e-09	72.0
rs:WP_026914641	DNA topoisomerase I [Gramella portivictoriae].	26.04	434	257	18	99	505	68	464	1e-09	72.0
rs:WP_036861839	DNA topoisomerase I [Prevotella melaninogenica].	24.29	531	309	21	7	505	6	475	1e-09	72.0
rs:WP_004952687	DNA topoisomerase I [Streptomyces mobaraensis].	24.30	461	274	17	97	505	90	527	1e-09	72.0
tr:X1KKS8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C02287 {ECO:0000313|EMBL:GAH90749.1}; Flags: Fragment;	27.94	383	218	16	162	504	1	365	1e-09	71.2
rs:WP_010777295	hypothetical protein [Enterococcus faecium].	37.29	118	64	5	5	118	3	114	1e-09	67.4
rs:WP_030838062	DNA topoisomerase I [Streptomyces hygroscopicus].	23.13	562	323	22	7	505	16	531	1e-09	72.0
rs:WP_022251253	DNA topoisomerase [Prevotella sp. CAG:386].	23.13	549	326	21	7	523	17	501	1e-09	72.0
rs:WP_010969164	DNA topoisomerase I [Sinorhizobium meliloti].	23.24	555	315	24	3	505	6	501	1e-09	72.0
tr:X7ZAG8_MYCKA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.78	471	290	16	86	504	27	480	1e-09	72.0
rs:WP_041844049	DNA topoisomerase I [Thermotoga sp. RQ7].	23.66	524	307	23	7	504	8	464	1e-09	71.6
rs:WP_014118434	DNA topoisomerase I [Oscillibacter valericigenes].	23.11	541	324	21	1	505	1	485	1e-09	72.0
rs:WP_021635915	DNA topoisomerase I [Clostridium sp. KLE 1755].	23.30	442	290	18	93	505	63	484	1e-09	71.6
rs:WP_044546116	DNA topoisomerase I, partial [Parabacteroides distasonis].	21.41	453	304	16	4	437	1	420	1e-09	70.9
rs:WP_020540892	DNA topoisomerase I [Nonomuraea coxensis].	22.04	549	339	18	7	505	14	523	1e-09	72.0
rs:WP_014186866	DNA topoisomerase I [Desulfosporosinus orientis].	25.37	544	302	26	3	504	2	483	1e-09	71.6
rs:WP_008956602	topoisomerase I [Halomonas sp. HAL1].	22.35	452	314	13	69	505	80	509	1e-09	72.0
rs:WP_003375272	DNA topoisomerase I [Clostridium botulinum].	23.49	545	330	23	7	517	6	497	1e-09	71.6
tr:U4PWA0_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.59	551	316	21	4	505	1	495	1e-09	72.0
rs:XP_003578369	PREDICTED: DNA topoisomerase 3-beta [Brachypodium distachyon].	22.83	622	376	29	1	575	1	565	1e-09	72.0
rs:WP_042840451	DNA topoisomerase I, partial [Salmonella enterica].	27.60	308	190	12	216	505	2	294	1e-09	71.6
rs:WP_010526611	DNA topoisomerase I [Thermophagus xiamenensis].	23.03	521	320	18	7	504	13	475	1e-09	71.6
rs:WP_009286991	MULTISPECIES: DNA topoisomerase I [Halomonas].	22.35	452	314	13	69	505	80	509	1e-09	72.0
rs:WP_041375056	DNA topoisomerase I [Prochlorococcus marinus].	25.55	454	258	19	101	505	85	507	1e-09	72.0
rs:WP_044157398	DNA topoisomerase I [Salinibacillus aidingensis].	24.53	424	266	16	112	505	82	481	1e-09	71.6
tr:A0A0B8TY06_LACCA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	24.37	316	204	11	213	505	2	305	1e-09	71.2
rs:XP_002495860	ZYRO0C04642p [Zygosaccharomyces rouxii].	22.73	629	378	29	7	569	3	589	1e-09	71.6
rs:WP_036886207	DNA topoisomerase I [Prevotella bivia].	23.84	537	305	22	7	505	6	476	1e-09	71.6
rs:WP_039423665	DNA topoisomerase I, partial [Porphyromonas gulae].	26.47	170	109	3	375	531	15	181	1e-09	69.7
gpu:CP009528_2347	DNA topoisomerase I [Methanosarcina barkeri MS]	23.90	544	323	20	48	548	52	547	1e-09	71.6
tr:A2C7C2_PROM3	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.55	454	258	19	101	505	102	524	1e-09	72.0
rs:XP_006656881	PREDICTED: uncharacterized protein LOC102708068 [Oryza brachyantha].	23.87	511	314	18	47	505	328	815	1e-09	72.0
rs:WP_023368568	DNA topoisomerase I [Mycobacterium kansasii].	23.78	471	290	16	86	504	84	537	1e-09	72.0
tr:H7ENR1_9SPIO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.92	531	317	24	5	504	43	517	1e-09	71.6
tr:A9FRC6_SORC5	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.22	585	315	22	5	505	4	532	1e-09	71.6
rs:WP_040843203	DNA topoisomerase I [Treponema saccharophilum].	23.92	531	317	24	5	504	28	502	1e-09	71.6
rs:WP_040661207	DNA topoisomerase I [Oscillibacter ruminantium].	22.94	545	320	21	1	505	1	485	1e-09	71.6
tr:W4PT77_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE22942.1};	28.23	209	134	3	97	304	20	213	1e-09	68.9
rs:WP_035557252	DNA topoisomerase I [Halomonas sp. KO116].	22.35	452	314	13	69	505	80	509	1e-09	71.6
rs:WP_039065471	DNA topoisomerase III, partial [Shigella boydii].	39.78	93	52	2	365	455	1	91	1e-09	67.0
rs:WP_013661399	topoisomerase I [Marinomonas mediterranea].	20.56	540	351	16	7	505	6	508	1e-09	71.6
rs:XP_007054991	PREDICTED: DNA topoisomerase 3-beta-1 [Chelonia mydas].	22.67	472	297	18	107	553	112	540	1e-09	71.6
tr:F9DBT9_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.17	433	258	13	7	431	25	399	1e-09	71.6
rs:WP_002347146	hypothetical protein, partial [Enterococcus faecium].	31.29	163	101	3	411	563	6	167	1e-09	70.1
rs:WP_008449636	DNA topoisomerase I [Prevotella amnii].	23.34	527	318	19	7	504	6	475	1e-09	71.6
rs:WP_029202375	DNA topoisomerase I [Ornithinimicrobium pekingense].	22.59	571	322	21	7	505	8	530	1e-09	71.6
rs:WP_036342825	DNA topoisomerase I [Mobiluncus mulieris].	25.31	482	267	20	1	430	1	441	1e-09	71.6
rs:WP_021651815	MULTISPECIES: DNA topoisomerase I [Clostridiales].	22.86	433	289	15	97	504	67	479	1e-09	71.6
rs:WP_023926303	DNA topoisomerase I [Prevotella nigrescens].	25.17	433	258	13	7	431	6	380	1e-09	71.6
rs:WP_019159531	DNA topoisomerase I [Brevibacterium senegalense].	23.13	575	318	21	7	505	11	537	1e-09	71.6
rs:WP_004572125	DNA topoisomerase I [Mobiluncus mulieris].	25.31	482	267	20	1	430	1	441	1e-09	71.6
rs:WP_046594252	DNA topoisomerase III, partial [Staphylococcus aureus].	26.37	201	130	7	52	245	4	193	1e-09	68.6
tr:A0A0A1MTC0_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.64	478	305	19	48	498	16	460	1e-09	71.6
rs:WP_035829502	DNA topoisomerase I [Cyanobium sp. CACIAM 14].	26.15	520	273	23	107	579	91	546	1e-09	71.6
rs:WP_036383720	DNA topoisomerase I [Mobiluncus mulieris].	25.31	482	267	20	1	430	1	441	1e-09	71.6
rs:WP_004014089	DNA topoisomerase I [Mobiluncus mulieris].	25.31	482	267	20	1	430	1	441	1e-09	71.6
rs:WP_010549533	DNA topoisomerase I [Brachybacterium paraconglomeratum].	22.78	632	384	25	7	590	8	583	1e-09	71.6
rs:WP_016553640	DNA topoisomerase I subunit omega [Rhizobium grahamii].	26.62	462	251	22	107	510	75	506	1e-09	71.6
tr:X1GRV3_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S07680 {ECO:0000313|EMBL:GAH47580.1}; Flags: Fragment;	28.76	233	122	9	7	236	5	196	1e-09	68.2
rs:WP_024992717	hypothetical protein, partial [Prevotella amnii].	26.70	221	132	7	5	213	3	205	1e-09	68.6
rs:WP_045223170	DNA topoisomerase I, partial [Desulfonatronum thioautotrophicum].	24.34	452	279	18	88	506	58	479	1e-09	71.6
rs:WP_022861227	DNA topoisomerase I [Bifidobacterium minimum].	20.54	560	338	20	7	505	8	521	1e-09	71.6
rs:WP_021132544	DNA topoisomerase I subunit omega [Phaeospirillum fulvum].	24.81	532	320	22	7	504	4	489	1e-09	71.6
rs:WP_035109892	DNA topoisomerase I [Clostridium tetani].	23.70	443	280	16	93	504	63	478	1e-09	71.2
rs:WP_013491419	DNA topoisomerase I [Intrasporangium calvum].	22.00	550	344	19	7	505	10	525	1e-09	71.6
rs:WP_038029314	DNA topoisomerase I [Thermonema rossianum].	25.99	431	256	19	103	505	74	469	1e-09	71.6
rs:WP_030342635	DNA topoisomerase I [Streptomyces sp. NRRL S-1022].	23.34	557	323	22	7	505	15	525	1e-09	71.6
rs:XP_006412616	hypothetical protein EUTSA_v10024242mg [Eutrema salsugineum].	25.56	532	292	21	47	510	420	915	1e-09	71.6
tr:W1AY89_KLEPN	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDK73336.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDK73336.1};	25.62	203	138	5	8	206	5	198	1e-09	68.6
tr:E9CLX8_9ENTR	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EFW12444.1}; Flags: Fragment;	28.57	217	138	9	2	214	116	319	1e-09	70.1
rs:WP_035207854	DNA topoisomerase I [Agrobacterium tumefaciens].	23.59	551	316	21	4	505	1	495	1e-09	71.6
rs:WP_027003233	DNA topoisomerase I [Flexibacter roseolus].	23.96	434	264	15	7	434	6	379	1e-09	71.6
rs:WP_007548544	DNA topoisomerase III, partial [Listeria fleischmannii].	29.22	154	100	4	5	156	4	150	1e-09	67.8
rs:WP_019408699	topoisomerase I [Pseudomonas psychrophila].	22.66	459	305	15	69	505	75	505	1e-09	71.6
rs:WP_034495748	MULTISPECIES: DNA topoisomerase I [Rhizobium/Agrobacterium group].	23.59	551	316	21	4	505	1	495	1e-09	71.6
rs:WP_037968522	DNA topoisomerase I [Streptomyces sp. SS].	23.75	560	317	22	7	505	15	525	1e-09	71.6
rs:WP_012821484	DNA topoisomerase I [Blattabacterium sp. (Periplaneta americana)].	24.83	439	262	16	7	437	6	384	1e-09	71.2
rs:WP_022127786	DNA topoisomerase [Ruminococcus sp. CAG:579].	23.91	435	267	15	107	505	76	482	1e-09	71.2
tr:W1ESZ2_ECOLX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDL25211.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL25211.1};	28.87	142	94	2	416	552	2	141	1e-09	68.6
rs:WP_031927251	hypothetical protein [Staphylococcus aureus].	26.37	201	130	7	52	245	5	194	1e-09	68.2
rs:XP_012749000	hypothetical protein SAMD00019534_112170 [Acytostelium subglobosum LB1].	22.48	556	357	20	8	534	6	516	2e-09	71.2
rs:WP_011307105	DNA topoisomerase [Methanosarcina barkeri].	24.49	539	318	22	48	548	52	539	2e-09	71.6
rs:WP_046598637	DNA topoisomerase III, partial [Staphylococcus aureus].	26.37	201	130	7	52	245	7	196	2e-09	68.2
rs:WP_015178581	DNA topoisomerase I [Oscillatoria nigro-viridis].	23.04	573	354	15	46	583	29	549	2e-09	71.6
rs:WP_021296476	DNA topoisomerase I [Alicyclobacillus acidoterrestris].	23.43	525	326	19	7	504	6	481	2e-09	71.2
tr:A0A077EBF0_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.33	463	295	17	64	504	9	433	2e-09	71.2
tr:W1FGI9_ENTCL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	26.69	311	195	12	213	505	8	303	2e-09	71.2
rs:WP_016459086	DNA topoisomerase I [Corynebacterium pyruviciproducens].	24.77	440	273	16	107	505	91	513	2e-09	71.6
rs:WP_028744828	DNA topoisomerase I [Rhizobium mesoamericanum].	27.06	462	249	22	107	510	75	506	2e-09	71.6
rs:WP_034443192	DNA topoisomerase I [Cloacibacillus evryensis].	24.67	531	313	18	5	505	79	552	2e-09	71.2
rs:WP_028741377	DNA topoisomerase I [Rhizobium leguminosarum].	25.11	466	273	22	97	510	65	506	2e-09	71.6
rs:WP_007232724	topoisomerase I [gamma proteobacterium HTCC2207].	22.88	555	343	22	80	598	88	593	2e-09	71.6
rs:WP_033416077	hypothetical protein, partial [Hahella ganghwensis].	23.79	517	317	20	63	538	19	499	2e-09	70.9
rs:WP_035270855	DNA topoisomerase I, partial [Desulfonatronum thiodismutans].	23.71	447	288	14	88	506	58	479	2e-09	71.2
rs:WP_032521294	DNA topoisomerase I [Prochlorococcus marinus].	25.00	512	301	17	101	579	85	546	2e-09	71.2
rs:WP_025289380	DNA topoisomerase I [Bibersteinia trehalosi].	23.22	435	283	17	93	505	101	506	2e-09	71.2
rs:WP_028257373	DNA topoisomerase I [Veillonella montpellierensis].	23.36	625	362	28	7	596	74	616	2e-09	71.2
rs:WP_018172633	DNA topoisomerase I [Microbacterium sp. 292MF].	23.30	588	350	21	7	550	8	538	2e-09	71.2
rs:XP_005966779	PREDICTED: DNA topoisomerase 3-alpha-like [Pantholops hodgsonii].	23.77	551	315	22	4	505	1	495	2e-09	71.2
rs:WP_029161493	DNA topoisomerase I [Clostridium scatologenes].	24.03	541	334	17	7	517	6	499	2e-09	71.2
tr:G9PXX1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.67	531	313	18	5	505	79	552	2e-09	71.2
rs:WP_036363021	DNA topoisomerase I [Mycobacterium asiaticum].	23.72	468	290	16	86	504	82	531	2e-09	71.2
rs:WP_017816939	DNA topoisomerase I [Acinetobacter baumannii].	24.54	485	293	22	46	504	28	465	2e-09	70.9
tr:K1TU90_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC73388.1};	30.38	158	103	5	260	413	15	169	2e-09	67.8
rs:WP_019987069	DNA topoisomerase I [Rudanella lutea].	24.19	434	258	14	7	430	6	378	2e-09	71.2
rs:WP_015769353	DNA topoisomerase I [Leptotrichia buccalis].	22.18	532	314	18	7	504	6	471	2e-09	71.2
rs:WP_040766049	DNA topoisomerase I [Tsukamurella sp. 1534].	23.74	594	343	20	7	550	17	550	2e-09	71.2
rs:WP_031806813	DNA topoisomerase III, partial [Staphylococcus aureus].	28.30	159	109	3	405	559	1	158	2e-09	69.7
rs:XP_008167010	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Chrysemys picta bellii].	22.46	472	298	18	107	553	112	540	2e-09	71.2
rs:WP_039234307	DNA topoisomerase I [Clostridium sp. K25].	23.49	545	330	23	7	517	6	497	2e-09	71.2
rs:WP_017639782	topoisomerase I [Pseudomonas sp. 313].	23.60	428	280	15	99	505	102	503	2e-09	71.2
rs:WP_030378629	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.13	562	318	24	7	505	15	525	2e-09	71.2
tr:A0A074WEW7_9PEZI	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:KEQ61046.1};	23.09	576	346	25	4	532	2	527	2e-09	71.2
rs:WP_035784394	DNA topoisomerase I [Clostridium botulinum].	23.99	521	327	18	7	505	6	479	2e-09	71.2
rs:WP_007294258	DNA topoisomerase I [delta proteobacterium MLMS-1].	22.78	562	324	21	7	510	6	515	2e-09	71.2
tr:J4SSP4_PASMD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	41.98	81	45	2	272	351	33	112	2e-09	66.6
rs:WP_010630966	DNA topoisomerase I [Sporolactobacillus vineae].	25.17	429	259	17	112	504	82	484	2e-09	71.2
tr:E0QNJ5_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.16	473	264	18	7	430	35	466	2e-09	71.2
rs:WP_033491154	DNA topoisomerase I [Bifidobacterium indicum].	20.32	571	341	18	7	505	8	536	2e-09	71.2
rs:WP_015432594	DNA topoisomerase 1 [Bibersteinia trehalosi].	23.22	435	283	17	93	505	101	506	2e-09	71.2
rs:WP_037388606	DNA topoisomerase III, partial [Serratia symbiotica].	28.91	211	133	9	8	214	5	202	2e-09	68.2
rs:WP_013882357	DNA topoisomerase I [[Cellvibrio] gilvus].	22.83	552	336	20	7	505	8	522	2e-09	71.2
rs:WP_022214408	DNA topoisomerase [Blautia sp. CAG:237].	23.82	445	278	16	93	504	63	479	2e-09	70.9
rs:WP_046186104	DNA topoisomerase I [Mycobacterium nebraskense].	23.98	467	290	17	86	504	85	534	2e-09	71.2
tr:L1MJJ4_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.11	442	268	18	93	505	73	480	2e-09	71.2
rs:WP_013852723	DNA topoisomerase I [Erysipelothrix rhusiopathiae].	25.00	588	371	22	36	596	9	553	2e-09	70.9
rs:WP_018596075	DNA topoisomerase I [Blautia producta].	23.83	449	275	19	93	504	63	481	2e-09	70.9
rs:WP_026430828	DNA topoisomerase I [Actinomyces georgiae].	23.04	573	324	22	1	505	1	524	2e-09	71.2
rs:WP_044969202	hypothetical protein, partial [Sorangium cellulosum].	22.67	494	277	17	93	505	59	528	2e-09	71.2
rs:WP_037117487	DNA topoisomerase I [Rhizobium sp. OV201].	26.62	462	251	22	107	510	75	506	2e-09	71.2
rs:WP_017727298	hypothetical protein, partial [Bacillus sp. L1(2012)].	25.14	346	195	13	7	336	6	303	2e-09	69.7
rs:WP_027601459	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	23.60	428	280	15	99	505	102	503	2e-09	71.2
rs:WP_018106628	hypothetical protein [Porphyromonas bennonis].	22.41	522	323	16	7	505	6	468	2e-09	71.2
tr:T2JTF5_CROWT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	24.71	429	267	14	91	482	74	483	2e-09	70.5
rs:WP_013769649	DNA topoisomerase I [Cellulomonas fimi].	22.28	561	339	22	7	505	8	533	2e-09	71.2
rs:WP_002350038	toprim domain protein, partial [Enterococcus faecium].	39.23	130	67	5	5	129	4	126	2e-09	67.0
rs:WP_013278603	DNA topoisomerase I [Acetohalobium arabaticum].	24.12	568	340	23	7	553	6	503	2e-09	70.9
rs:WP_024314695	MULTISPECIES: DNA topoisomerase I [Rhizobium].	26.62	462	251	22	107	510	75	506	2e-09	71.2
rs:WP_022784507	DNA topoisomerase I [Lachnospiraceae bacterium NK4A179].	23.61	449	284	17	93	505	63	488	2e-09	70.9
rs:WP_031903954	DNA topoisomerase III, partial [Staphylococcus aureus].	31.97	147	90	5	5	145	3	145	2e-09	67.0
rs:WP_046400761	DNA topoisomerase I [Francisella tularensis].	22.47	543	322	20	8	505	1	489	2e-09	70.9
tr:W6RSU7_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.62	462	251	22	107	510	76	507	2e-09	71.2
rs:WP_044038350	DNA topoisomerase I [Clostridium sp. M2/40].	24.23	549	326	22	7	517	6	502	2e-09	70.9
rs:WP_045458631	DNA topoisomerase I [Sporocytophaga myxococcoides].	21.74	621	368	23	7	581	6	554	2e-09	70.9
rs:WP_026187416	DNA topoisomerase I [Ensifer sp. BR816].	23.47	554	313	24	4	505	1	495	2e-09	71.2
rs:WP_032820919	topoisomerase I, partial [Oenococcus oeni].	30.05	193	112	8	279	459	5	186	2e-09	67.8
rs:WP_039918361	DNA topoisomerase I, partial [Synergistes sp. 3_1_syn1].	24.76	529	311	18	7	505	2	473	2e-09	70.9
rs:WP_024653225	DNA topoisomerase I [Borrelia persica].	22.64	605	360	24	1	561	1	541	2e-09	70.9
rs:WP_040559679	DNA topoisomerase I [Prevotella histicola].	24.21	541	295	23	7	504	6	474	2e-09	70.9
rs:WP_033952290	DNA topoisomerase I [Streptomyces sp. CNQ431].	23.52	557	321	24	7	505	15	524	2e-09	71.2
rs:WP_030228518	DNA topoisomerase I [Streptomyces lavendulae].	22.36	559	325	22	7	505	15	524	2e-09	71.2
tr:G6AHM1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.21	541	295	23	7	504	12	480	2e-09	70.9
rs:WP_015915683	DNA topoisomerase I [Agrobacterium vitis].	25.00	444	265	20	107	505	75	495	2e-09	70.9
rs:WP_037978261	DNA topoisomerase I [Tannerella sp. oral taxon BU063].	23.78	534	301	22	7	504	6	469	2e-09	70.9
rs:WP_020366069	hypothetical protein, partial [Staphylococcus epidermidis].	36.52	115	68	3	279	389	19	132	2e-09	66.6
rs:WP_034247793	DNA topoisomerase I [Actinotalea fermentans].	21.14	577	343	20	1	505	1	537	2e-09	70.9
tr:C3AXE7_BACMY	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:EEM01684.1};	29.74	195	121	5	367	547	8	200	2e-09	68.6
tr:V7PSM0_9APIC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETB62614.1};	28.21	234	132	11	307	531	9	215	2e-09	69.3
rs:WP_020049515	DNA topoisomerase I [Rhizobium leguminosarum].	25.65	460	258	22	107	510	75	506	2e-09	70.9
rs:XP_007834111	hypothetical protein PFICI_07339 [Pestalotiopsis fici W106-1].	24.17	571	331	25	7	532	3	516	2e-09	70.9
rs:WP_022389687	DNA topoisomerase [Tannerella sp. CAG:51].	22.92	528	313	21	7	504	6	469	2e-09	70.9
rs:WP_016339331	DNA topoisomerase I [Spiroplasma chrysopicola].	23.80	416	271	15	107	504	84	471	2e-09	70.5
tr:G1UZZ8_9DELT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGW42403.1};	28.31	166	107	4	7	170	6	161	2e-09	67.4
rs:WP_045384234	DNA topoisomerase I [Mycobacterium kyorinense].	24.21	508	306	19	86	550	82	553	2e-09	70.9
rs:WP_032495452	DNA topoisomerase, partial [Enterococcus thailandicus].	30.36	168	108	5	385	544	1	167	2e-09	69.3
rs:WP_016532565	DNA topoisomerase III, partial [Klebsiella pneumoniae].	27.27	143	97	2	411	548	2	142	2e-09	67.8
rs:XP_004223545	DNA topoisomerase III alpha [Plasmodium cynomolgi strain B].	23.02	582	342	24	8	531	9	542	2e-09	70.9
tr:A0A0A1H296_9LACO	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:BAP86821.1};	26.70	191	131	4	73	260	5	189	2e-09	67.4
rs:WP_019894900	DNA topoisomerase I [Thiomicrospira halophila].	24.81	520	311	21	7	505	5	465	2e-09	70.9
sp:TOP1P_MIMIV	RecName: Full=DNA topoisomerase 1 type prokaryotic; EC=5.99.1.2;	26.35	406	219	18	7	389	5	353	2e-09	70.9
tr:F3J5T6_PSEAP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH79762.1}; Flags: Fragment;	34.04	141	82	3	417	548	1	139	2e-09	68.2
rs:WP_036532312	DNA topoisomerase I, partial [Nocardia cyriacigeorgica].	25.60	457	272	18	7	430	19	440	2e-09	70.1
rs:WP_045230664	DNA topoisomerase I [Agrobacterium rubi].	23.64	550	317	24	4	505	1	495	2e-09	70.9
rs:WP_022600088	DNA topoisomerase I [Coprobacter fastidiosus].	22.92	528	313	21	7	504	6	469	2e-09	70.9
rs:WP_023127875	DNA topoisomerase I [Pseudomonas aeruginosa].	25.40	437	266	15	97	504	74	479	2e-09	70.9
rs:WP_006170276	DNA topoisomerase I [Synechococcus sp. WH 5701].	23.85	436	276	14	107	505	91	507	2e-09	70.9
rs:WP_012756988	DNA topoisomerase I [Rhizobium leguminosarum].	26.07	468	246	24	107	510	75	506	2e-09	70.9
rs:WP_023539660	DNA topoisomerase I [Streptomyces niveus].	22.62	557	327	21	7	505	15	525	2e-09	70.9
rs:WP_013261363	topoisomerase I [gamma proteobacterium HdN1].	22.12	547	337	20	7	505	6	511	2e-09	70.9
rs:WP_044063101	DNA topoisomerase I [Prevotella sp. oral taxon 473].	25.11	442	268	18	93	505	62	469	2e-09	70.9
rs:WP_037122099	DNA topoisomerase I [Rhizobium sp. CF097].	25.91	467	268	22	97	510	65	506	2e-09	70.9
rs:WP_039702831	hypothetical protein, partial [marine actinobacterium MedAcidi-G2A].	22.21	653	383	25	7	595	8	599	2e-09	70.5
tr:L2HBN5_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELA53336.1};	32.37	139	82	4	5	138	3	134	2e-09	67.0
rs:XP_005281154	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Chrysemys picta bellii].	24.51	355	210	16	216	553	91	404	2e-09	70.9
rs:WP_040201666	DNA topoisomerase I, partial [Klebsiella pneumoniae].	25.16	461	271	20	7	437	6	422	2e-09	70.1
rs:WP_022417382	DNA topoisomerase [Eubacterium sp. CAG:841].	25.88	452	266	20	93	506	63	483	2e-09	70.9
rs:WP_034558163	DNA topoisomerase I [Helicobacter muridarum].	23.80	521	306	20	47	504	16	508	2e-09	70.9
rs:WP_041369758	DNA topoisomerase I, partial [Nakamurella multipartita].	22.73	550	346	18	2	505	12	528	2e-09	70.9
rs:WP_041859254	hypothetical protein, partial [Candidatus Solibacter usitatus].	22.65	543	320	24	7	505	6	492	2e-09	70.9
rs:WP_006045293	DNA topoisomerase I [Prevotella pallens].	25.69	436	250	16	7	430	25	398	2e-09	70.9
tr:S5VI98_ENTFC	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:AGS77016.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AGS77016.1};	31.21	157	97	3	417	563	2	157	2e-09	69.3
rs:WP_012424370	DNA topoisomerase I [Clostridium botulinum].	23.47	524	326	19	7	505	6	479	2e-09	70.5
rs:WP_028011292	DNA topoisomerase I [Sinorhizobium meliloti].	23.10	554	315	24	4	505	1	495	2e-09	70.9
rs:WP_019218588	DNA topoisomerase I [Bartonella sp. R4(2010)].	23.54	548	312	25	7	505	4	493	2e-09	70.9
tr:C8X984_NAKMY	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.73	550	346	18	2	505	12	528	2e-09	70.9
rs:WP_010026557	DNA topoisomerase I [Sporolactobacillus inulinus].	25.00	436	252	18	112	504	82	485	3e-09	70.5
rs:WP_032973213	DNA topoisomerase I, partial [Stenotrophomonas maltophilia].	26.98	315	184	12	276	568	14	304	3e-09	70.5
rs:WP_037063478	DNA topoisomerase I [Rhizobium leguminosarum].	26.84	462	250	22	107	510	75	506	3e-09	70.9
rs:WP_028977943	DNA topoisomerase I [Sporolactobacillus terrae].	25.00	436	252	18	112	504	82	485	3e-09	70.5
rs:WP_026160957	DNA topoisomerase I [Sinorhizobium medicae].	23.51	553	314	23	4	505	1	495	3e-09	70.9
rs:WP_024311648	MULTISPECIES: DNA topoisomerase I [Sinorhizobium].	23.51	553	314	23	4	505	1	495	3e-09	70.9
rs:WP_020795116	hypothetical protein [Pseudomonas sp. G5(2012)].	22.65	468	298	17	76	505	46	487	3e-09	70.5
rs:WP_031502913	DNA topoisomerase I [Pseudothermotoga hypogea].	23.76	425	276	15	99	504	67	462	3e-09	70.5
rs:WP_005938434	DNA topoisomerase I [Gordonia hirsuta].	22.26	557	347	19	7	510	15	538	3e-09	70.9
rs:WP_004380549	DNA topoisomerase I [Prevotella oulorum].	25.06	451	265	14	7	448	6	392	3e-09	70.5
rs:WP_004138408	DNA topoisomerase I [Gardnerella vaginalis].	21.88	544	340	19	7	505	8	511	3e-09	70.9
rs:WP_002331854	DNA topoisomerase 1 [Enterococcus faecium].	23.95	526	321	18	7	504	7	481	3e-09	70.5
rs:WP_028002973	DNA topoisomerase I [Sinorhizobium meliloti].	23.10	554	315	24	4	505	1	495	3e-09	70.9
rs:WP_042743042	DNA topoisomerase III, partial [Staphylococcus aureus].	26.50	200	129	7	53	245	1	189	3e-09	67.4
rs:WP_027989610	DNA topoisomerase I [Sinorhizobium meliloti].	23.10	554	315	24	4	505	1	495	3e-09	70.9
rs:WP_017963880	DNA topoisomerase I [Rhizobium leguminosarum].	25.87	460	257	22	107	510	75	506	3e-09	70.9
rs:WP_027300609	DNA topoisomerase I [Rhodospirillales bacterium URHD0088].	24.35	542	319	24	4	505	1	491	3e-09	70.9
rs:WP_003773150	DNA topoisomerase I [Erysipelothrix rhusiopathiae].	25.00	588	371	22	36	596	9	553	3e-09	70.5
rs:WP_035791091	DNA topoisomerase I [Clostridium botulinum].	23.65	520	330	18	7	505	6	479	3e-09	70.5
rs:WP_020598650	DNA topoisomerase I [Spirosoma panaciterrae].	24.25	433	261	14	7	431	6	379	3e-09	70.9
rs:WP_027933602	DNA topoisomerase I [Amycolatopsis thermoflava].	22.92	554	332	20	7	505	23	536	3e-09	70.9
rs:WP_013237965	MULTISPECIES: DNA topoisomerase I [Clostridium].	23.26	533	316	23	7	504	6	480	3e-09	70.5
rs:WP_020479289	DNA topoisomerase I [Sinorhizobium meliloti].	23.10	554	315	24	4	505	1	495	3e-09	70.9
rs:WP_027665389	DNA topoisomerase I [Rhizobium leguminosarum].	25.85	468	247	24	107	510	75	506	3e-09	70.5
rs:WP_022293461	DNA topoisomerase [Eubacterium rectale CAG:36].	24.82	556	331	23	7	540	6	496	3e-09	70.5
rs:XP_010048495	PREDICTED: uncharacterized protein LOC104437275 [Eucalyptus grandis].	23.82	529	315	22	36	505	350	849	3e-09	70.9
rs:WP_013054252	DNA topoisomerase I [Mycoplasma crocodyli].	22.14	524	324	21	7	504	6	471	3e-09	70.5
rs:WP_027454770	DNA topoisomerase I [Prevotella brevis].	23.94	447	282	15	88	504	56	474	3e-09	70.5
rs:WP_025069710	DNA topoisomerase I [Prevotella oulorum].	24.15	530	304	19	7	504	6	469	3e-09	70.5
rs:WP_046667740	DNA topoisomerase I [Neorhizobium galegae].	25.82	457	265	22	97	505	65	495	3e-09	70.5
tr:D3AV32_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFC94324.1}; Flags: Fragment;	26.88	186	113	4	380	549	1	179	3e-09	68.2
tr:D6E501_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.82	556	331	23	7	540	6	496	3e-09	70.5
rs:WP_044102077	DNA topoisomerase III, partial [Xanthomonas citri].	28.15	135	77	2	436	552	2	134	3e-09	67.4
tr:W4PSY6_9BACE	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE22941.1};	30.26	195	123	8	376	566	36	221	3e-09	67.4
tr:Q01N68_SOLUE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.65	543	320	24	7	505	6	492	3e-09	70.5
rs:WP_033389985	DNA topoisomerase I, partial [Kibdelosporangium aridum].	23.39	466	292	16	86	504	6	453	3e-09	70.5
tr:C2D5U5_LACBR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEI69841.1}; Flags: Fragment;	27.36	212	135	6	402	603	18	220	3e-09	68.6
rs:WP_031811093	DNA topoisomerase III, partial [Staphylococcus aureus].	33.86	127	76	4	5	127	3	125	3e-09	66.2
rs:WP_044908119	DNA topoisomerase I [Lachnospiraceae bacterium MC2017].	23.35	531	324	24	7	504	6	486	3e-09	70.5
rs:WP_023161606	Topoisomerase IA, partial [Candidatus Phytoplasma solani].	26.56	418	255	17	107	504	79	464	3e-09	70.1
rs:XP_004202802	Piso0_001663 [Millerozyma farinosa CBS 7064].	22.15	587	354	21	7	547	3	532	3e-09	70.1
tr:Q5VMY4_ORYSJ	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	24.14	522	315	19	47	510	314	812	3e-09	70.5
rs:WP_027872316	DNA topoisomerase I [[Eubacterium] cellulosolvens].	23.58	530	320	21	7	505	6	481	3e-09	70.5
rs:WP_026890284	DNA topoisomerase I [[Clostridium] aerotolerans].	23.08	442	289	14	93	504	63	483	3e-09	70.5
gpu:CP009524_2457	DNA topoisomerase I [Methanosarcina sp. Kolksee]	24.23	582	348	24	8	548	6	535	3e-09	70.5
rs:WP_027685122	DNA topoisomerase I [Rhizobium leguminosarum].	26.29	464	250	24	107	510	75	506	3e-09	70.5
rs:WP_036914127	MULTISPECIES: DNA topoisomerase I [Prochlorococcus].	26.07	445	255	20	107	505	91	507	3e-09	70.5
rs:WP_035641699	DNA topoisomerase I [Lachnospiraceae bacterium FE2018].	24.66	438	281	16	97	505	67	484	3e-09	70.5
tr:A0A0C7C669_9FUNG	SubName: Full=RMATCC62417_13354 protein {ECO:0000313|EMBL:CEG78806.1};	23.64	478	305	19	48	498	16	460	3e-09	70.5
rs:WP_027305949	DNA topoisomerase I [Campylobacter cuniculorum].	24.41	426	280	14	101	505	69	473	3e-09	70.1
rs:WP_035433370	topoisomerase, partial [Lactobacillus fermentum].	23.80	416	278	15	7	405	5	398	3e-09	70.5
rs:WP_017991042	DNA topoisomerase I [Rhizobium leguminosarum].	25.65	460	258	22	107	510	75	506	3e-09	70.5
rs:WP_034795369	DNA topoisomerase I [Ensifer adhaerens].	23.10	554	315	23	4	505	1	495	3e-09	70.5
rs:WP_027463868	hypothetical protein [Deinococcus ficus].	24.88	430	267	17	107	504	89	494	3e-09	70.1
rs:WP_028733673	DNA topoisomerase I [Rhizobium leguminosarum].	26.29	464	250	24	107	510	75	506	3e-09	70.5
rs:WP_037194447	DNA topoisomerase I [Rhizobium sp. OK494].	26.36	459	257	22	107	510	75	507	3e-09	70.5
rs:WP_028006081	DNA topoisomerase I [Sinorhizobium meliloti].	23.10	554	315	24	4	505	1	495	3e-09	70.5
rs:WP_003533027	DNA topoisomerase I [Sinorhizobium meliloti].	23.10	554	315	24	4	505	1	495	3e-09	70.5
tr:T1AKL2_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EQD61116.1}; Flags: Fragment;	30.95	168	97	8	293	450	1	159	3e-09	67.0
tr:U6E398_9MOLU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	26.56	418	255	17	107	504	79	464	3e-09	70.1
rs:WP_020392876	DNA topoisomerase I [Kribbella catacumbae].	22.57	545	340	19	7	505	1	509	3e-09	70.5
rs:WP_002366149	toprim domain protein, partial [Enterococcus faecium].	38.46	130	68	5	5	129	3	125	3e-09	66.2
rs:WP_017985457	DNA topoisomerase I [Amycolatopsis methanolica].	22.92	554	332	20	7	505	23	536	3e-09	70.5
tr:A0A0D6SKK9_9RHIZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KIV69166.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KIV69166.1};	25.22	448	259	18	107	505	34	454	3e-09	70.5
rs:WP_018069492	DNA topoisomerase I [Rhizobium leguminosarum].	25.88	456	262	22	107	510	75	506	3e-09	70.5
rs:WP_041488844	DNA topoisomerase I, partial [Bacillus mycoides].	28.40	162	92	2	110	271	1	138	3e-09	66.2
tr:V7HYT0_9LACO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.69	486	305	19	44	504	1	450	3e-09	70.1
rs:WP_018241618	DNA topoisomerase I [Rhizobium leguminosarum].	26.29	464	250	24	107	510	75	506	3e-09	70.5
rs:WP_010226976	MULTISPECIES: topoisomerase I [Pseudomonas].	22.59	425	288	13	99	505	104	505	3e-09	70.5
rs:WP_046636596	DNA topoisomerase I [Neorhizobium galegae].	25.22	456	269	21	97	505	65	495	3e-09	70.5
rs:WP_003547455	DNA topoisomerase I [Rhizobium leguminosarum].	25.65	460	258	22	107	510	75	506	3e-09	70.5
tr:A0A0E0E8K2_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OMERI07G04560.1};	22.37	532	342	18	1	498	1	495	3e-09	70.5
rs:WP_010731591	hypothetical protein [Enterococcus faecalis].	37.07	116	63	5	7	118	6	115	3e-09	65.9
rs:WP_010831330	DNA topoisomerase I [Nocardioides sp. CF8].	23.79	454	281	16	97	505	81	514	4e-09	70.5
rs:WP_018578850	DNA topoisomerase I [Erysipelothrix tonsillarum].	25.00	588	371	22	36	596	9	553	4e-09	70.1
rs:WP_022519081	DNA topoisomerase [Roseburia sp. CAG:100].	23.76	442	284	20	93	504	63	481	4e-09	70.1
rs:WP_026230854	DNA topoisomerase I [Rhizobium gallicum].	26.29	464	250	24	107	510	75	506	4e-09	70.5
tr:D1W2V0_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.35	531	309	20	7	505	20	484	4e-09	70.1
tr:J6D7M6_ENTFC	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EJX92842.1};	38.46	130	68	5	5	129	3	125	4e-09	66.2
tr:A0A0E0HP23_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA06G12620.2};	24.14	522	315	19	47	510	314	812	4e-09	70.5
rs:WP_015335647	DNA topoisomerase 1 [Desulfovibrio hydrothermalis].	24.30	535	307	22	7	505	6	478	4e-09	70.1
rs:WP_037136048	DNA topoisomerase I [Rhizobium leucaenae].	25.93	459	259	22	107	510	75	507	4e-09	70.1
rs:WP_028046126	DNA topoisomerase I [Cellulomonas sp. URHE0023].	23.15	553	334	21	7	505	8	523	4e-09	70.5
tr:G0MZ90_CAEBE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.26	593	379	23	1	556	545	1092	4e-09	70.5
rs:WP_015853669	DNA topoisomerase I [Desulfovibrio salexigens].	23.78	534	309	19	7	504	6	477	4e-09	70.1
rs:WP_022023449	DNA topoisomerase [Acinetobacter sp. CAG:196].	24.40	455	294	16	80	504	62	496	4e-09	70.1
rs:WP_034685923	DNA topoisomerase I [Chryseobacterium piperi].	21.65	522	321	20	7	504	6	463	4e-09	70.1
rs:WP_026449335	DNA topoisomerase I [Actinopolyspora mortivallis].	23.30	455	282	15	97	505	105	538	4e-09	70.5
rs:WP_021668772	hypothetical protein, partial [Prevotella disiens].	30.06	163	99	4	376	526	28	187	4e-09	67.0
rs:WP_044822296	DNA topoisomerase I, partial [Bacillus thuringiensis].	26.25	320	197	11	112	414	82	379	4e-09	69.3
rs:WP_026422883	DNA topoisomerase I [Actinokineospora inagensis].	23.67	566	327	19	7	510	23	545	4e-09	70.5
rs:WP_006704667	topoisomerase I [Candidatus Regiella insecticola].	26.39	432	259	18	101	505	108	507	4e-09	70.1
rs:WP_036411215	DNA topoisomerase I [Mycobacterium gastri].	23.35	471	292	16	86	504	91	544	4e-09	70.1
rs:WP_024321098	DNA topoisomerase I [Rhizobium leguminosarum].	25.88	456	262	22	107	510	75	506	4e-09	70.1
rs:WP_037969390	DNA topoisomerase I [Streptosporangium amethystogenes].	23.23	551	329	20	7	505	1	509	4e-09	70.1
rs:WP_026529492	DNA topoisomerase I [Arthrobacter sanguinis].	22.91	550	333	19	7	505	14	523	4e-09	70.1
rs:WP_029731298	DNA topoisomerase I [Dorea sp. AGR2135].	22.62	526	329	21	7	504	6	481	4e-09	70.1
rs:WP_015796992	DNA topoisomerase I [Catenulispora acidiphila].	23.37	552	330	20	7	504	17	529	4e-09	70.1
rs:WP_046483688	DNA topoisomerase I [Oceanospirillaceae bacterium ASP10-02a].	23.31	429	280	15	99	505	108	509	4e-09	70.1
tr:A0A0D9VPW6_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:LPERR03G04240.2};	23.42	585	349	27	8	546	14	545	4e-09	70.1
rs:WP_026209234	DNA topoisomerase I [Catelliglobosispora koreensis].	23.01	552	326	19	7	504	10	516	4e-09	70.1
tr:A6BH91_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.74	532	322	20	7	504	10	486	4e-09	70.1
rs:XP_002554555	KLTH0F08118p [Lachancea thermotolerans].	22.61	522	314	22	48	532	60	528	4e-09	70.1
rs:WP_006312670	MULTISPECIES: DNA topoisomerase I [Agrobacterium].	22.77	549	323	20	4	505	1	495	4e-09	70.1
tr:A0A0A7V345_9SPIO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00003390}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.79	615	361	22	1	565	1	545	4e-09	70.1
rs:WP_040561971	DNA topoisomerase I [Prevotella buccalis].	23.35	531	309	20	7	505	6	470	4e-09	70.1
rs:WP_008189836	DNA topoisomerase I [Moorea producens].	24.56	566	321	24	46	566	29	533	4e-09	70.1
rs:WP_018484047	DNA topoisomerase I [Rhizobium leguminosarum].	25.87	460	257	22	107	510	75	506	4e-09	70.1
rs:WP_038151015	DNA topoisomerase I [Veillonella montpellierensis].	23.36	625	362	28	7	596	74	616	4e-09	70.1
tr:W4I284_MYCGS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.35	471	292	16	86	504	54	507	4e-09	70.1
tr:G0PNJ8_CAEBE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.93	353	218	15	217	556	30	348	4e-09	70.1
rs:WP_009237164	DNA topoisomerase I [Prevotella sp. oral taxon 472].	24.36	583	332	23	7	552	6	516	4e-09	70.1
rs:WP_004378157	DNA topoisomerase I [Prevotella oris].	23.76	526	313	20	7	505	6	470	4e-09	70.1
rs:WP_018494099	DNA topoisomerase I [Rhizobium leguminosarum].	25.88	456	262	22	107	510	75	506	4e-09	70.1
rs:WP_016775814	DNA topoisomerase I [Anaerophaga thermohalophila].	22.86	525	327	18	1	504	7	474	4e-09	70.1
tr:S6EZ85_ZYGB2	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.67	600	356	25	7	546	3	560	4e-09	69.7
rs:WP_033180310	DNA topoisomerase I [Rhizobium leguminosarum].	25.66	456	263	22	107	510	75	506	4e-09	70.1
tr:B6YQH0_AZOPC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.69	476	317	16	47	504	21	463	4e-09	70.1
rs:WP_040260718	DNA topoisomerase I [Pseudomonas sp. CB1].	22.88	437	292	13	88	505	92	502	4e-09	70.1
rs:WP_005337825	DNA topoisomerase I [Dorea formicigenerans].	22.62	526	329	21	7	504	6	481	4e-09	69.7
rs:XP_006688044	hypothetical protein CANTEDRAFT_108430 [Candida tenuis ATCC 10573].	23.97	609	368	28	7	572	3	559	4e-09	69.7
rs:WP_009318380	DNA topoisomerase I [Tannerella sp. 6_1_58FAA_CT1].	23.44	529	309	22	7	504	6	469	4e-09	70.1
tr:T1BWI3_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD77316.1};	23.20	362	218	10	7	349	6	326	4e-09	68.9
tr:K9SQT0_9SYNE	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.95	522	303	18	89	568	72	541	4e-09	70.1
rs:WP_026966063	DNA topoisomerase I [Algoriphagus terrigena].	21.79	647	389	25	7	607	6	581	4e-09	70.1
rs:WP_040248414	DNA topoisomerase I [Psychroserpens mesophilus].	25.60	500	290	25	106	568	76	530	4e-09	70.1
rs:WP_016628540	hypothetical protein [Enterococcus faecium].	30.34	145	85	3	108	239	1	142	4e-09	66.2
rs:WP_013115817	DNA topoisomerase I [Cellulomonas flavigena].	23.30	558	329	21	7	505	8	525	4e-09	70.1
tr:A0A0D9VPW5_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:LPERR03G04240.1};	23.42	585	349	27	8	546	14	545	4e-09	70.1
rs:WP_033517008	DNA topoisomerase I [Bifidobacterium cuniculi].	22.58	558	324	23	7	505	8	516	4e-09	70.1
tr:K2F398_9BACT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.80	521	329	17	7	505	6	480	4e-09	69.7
rs:WP_018748115	DNA topoisomerase I [Chitiniphilus shinanonensis].	26.56	448	267	18	107	514	77	502	4e-09	70.1
tr:T1A8I7_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD53322.1}; Flags: Fragment;	22.60	354	230	11	5	343	6	330	4e-09	68.9
tr:D4M4K1_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.30	442	286	16	93	504	63	481	4e-09	69.7
rs:WP_025837075	DNA topoisomerase I [Prevotella scopos].	24.49	539	296	20	7	504	6	474	4e-09	70.1
rs:WP_047316417	DNA topoisomerase I [Mycobacterium haemophilum].	23.98	517	305	19	86	550	89	569	5e-09	70.1
rs:WP_041572492	DNA topoisomerase I, partial [Candidatus Azobacteroides pseudotrichonymphae].	22.69	476	317	16	47	504	21	463	5e-09	69.7
tr:F8WKE5_STAAU	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:BAK53124.1};	26.00	200	130	7	53	245	1	189	5e-09	66.6
tr:L2JGS7_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELA79744.1};	38.46	130	68	5	5	129	4	126	5e-09	66.6
rs:WP_022317494	MULTISPECIES: DNA topoisomerase [Prevotella].	23.25	529	317	19	7	505	6	475	5e-09	69.7
rs:WP_019822225	hypothetical protein, partial [Vibrio splendidus].	32.86	140	84	5	4	140	1	133	5e-09	65.9
tr:A0A0E0A851_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM06G11680.2};	24.14	522	315	19	47	510	314	812	5e-09	70.1
rs:WP_015391419	DNA topoisomerase 1 [Clostridium saccharoperbutylacetonicum].	24.67	531	311	23	7	505	6	479	5e-09	69.7
rs:WP_009003194	DNA topoisomerase I [Clostridium sp. D5].	22.40	442	290	18	93	504	63	481	5e-09	69.7
tr:W1Q971_OGAPD	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:ESW97356.1}; EC=5.99.1.2 {ECO:0000313|EMBL:ESW97356.1};	23.65	575	365	22	7	546	3	538	5e-09	69.7
rs:WP_028901497	DNA topoisomerase I [Prevotella corporis].	23.51	536	305	20	7	504	6	474	5e-09	69.7
rs:WP_036405715	DNA topoisomerase I [Mycobacterium kansasii].	23.57	471	291	16	86	504	93	546	5e-09	70.1
rs:WP_042849901	DNA topoisomerase I [Prochlorococcus sp. MIT 0604].	24.85	515	298	19	101	579	85	546	5e-09	69.7
rs:WP_034336155	DNA topoisomerase I [Commensalibacter sp. MX01].	24.73	554	315	25	7	510	5	506	5e-09	69.7
rs:WP_025791346	DNA topoisomerase I [Prevotella histicola].	24.03	541	296	23	7	504	6	474	5e-09	69.7
rs:WP_041429665	DNA topoisomerase I, partial [Synechococcus sp. PCC 7502].	23.95	522	303	18	89	568	72	541	5e-09	69.7
rs:WP_012115886	DNA topoisomerase I [Xanthobacter autotrophicus].	24.19	554	322	23	4	510	1	503	5e-09	69.7
rs:WP_036879037	DNA topoisomerase I [Prevotella oryzae].	23.56	522	317	19	7	504	6	469	5e-09	69.7
rs:WP_038994330	DNA topoisomerase I [Pseudomonas putida].	22.59	425	288	13	99	505	104	505	5e-09	69.7
rs:WP_040473085	topoisomerase I, partial [Lactobacillus coryniformis].	26.89	212	136	6	402	603	14	216	5e-09	68.2
rs:WP_039559607	DNA topoisomerase III, partial [Vibrio vulnificus].	28.49	186	119	5	4	184	1	177	5e-09	66.6
rs:WP_019948085	hypothetical protein [Hymenobacter aerophilus].	21.79	537	313	21	7	505	6	473	5e-09	69.7
rs:WP_005767202	DNA topoisomerase I [Bartonella bacilliformis].	23.77	547	312	25	7	505	4	493	5e-09	69.7
rs:WP_033874334	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	39.13	92	54	1	461	552	7	96	5e-09	66.2
tr:A0A069CW26_9LACT	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:GAK31592.1};	32.82	131	76	4	4	129	2	125	5e-09	66.2
rs:WP_020487473	DNA topoisomerase I [Sinorhizobium meliloti].	23.10	554	315	24	4	505	1	495	5e-09	69.7
rs:WP_028982117	DNA topoisomerase I [Sporocytophaga myxococcoides].	21.26	621	371	23	7	581	6	554	5e-09	69.7
rs:WP_034500488	DNA topoisomerase I [Actinomyces sp. S6-Spd3].	22.11	570	331	20	1	505	1	522	5e-09	69.7
rs:WP_008270706	DNA topoisomerase I [Flavobacteriales bacterium ALC-1].	27.70	426	246	19	106	504	76	466	5e-09	69.7
rs:WP_020422667	DNA topoisomerase I [Amycolatopsis sp. ATCC 39116].	22.92	554	332	20	7	505	23	536	5e-09	69.7
rs:WP_005360176	DNA topoisomerase I [Eubacterium ventriosum].	24.30	428	269	17	107	504	77	479	5e-09	69.7
rs:WP_030898447	DNA topoisomerase I [Streptomyces sp. NRRL F-5126].	23.26	460	279	15	97	505	89	525	5e-09	69.7
rs:WP_046800293	DNA topoisomerase I [Agrobacterium sp. LC34].	23.05	551	319	21	4	505	1	495	5e-09	69.7
rs:WP_016338978	DNA topoisomerase I [Spiroplasma chrysopicola].	24.04	416	270	15	107	504	84	471	5e-09	69.3
tr:X7YHI8_MYCKA	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.57	471	291	16	86	504	27	480	5e-09	69.7
rs:WP_041271527	DNA topoisomerase I, partial [Desulfovibrio aespoeensis].	23.37	522	333	19	7	505	6	483	5e-09	69.7
rs:WP_021778244	DNA topoisomerase I [Dokdonia sp. MED134].	24.58	537	309	24	7	512	6	477	5e-09	69.7
rs:WP_022802495	DNA topoisomerase I [Deinococcus sp. 2009].	24.34	452	284	18	86	504	68	494	5e-09	69.7
rs:WP_043594793	DNA topoisomerase I [Frigoribacterium sp. MEB024].	23.38	462	273	18	7	430	8	426	5e-09	69.7
rs:WP_010318059	DNA topoisomerase I [Synechococcus sp. CB0205].	25.56	446	261	18	107	505	91	512	5e-09	69.7
rs:WP_031580966	DNA topoisomerase I [Lachnospiraceae bacterium AC2028].	22.80	443	286	16	93	504	63	480	5e-09	69.7
rs:WP_026031461	DNA topoisomerase I [Sinorhizobium meliloti].	23.74	556	307	26	4	505	1	493	5e-09	69.7
tr:J9FUN1_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EJW98213.1};	22.65	521	326	16	7	505	6	471	6e-09	69.7
rs:WP_041843678	DNA topoisomerase I [Bartonella bacilliformis].	23.77	547	312	25	7	505	4	493	6e-09	69.7
rs:WP_045018655	DNA topoisomerase I [Rhizobium nepotum].	23.03	547	324	21	4	505	1	495	6e-09	69.7
rs:WP_040152282	DNA topoisomerase III, partial [Xanthomonas citri].	29.23	130	72	2	441	552	14	141	6e-09	66.6
gp:CP002744_994	DNA topoisomerase I/SWI domain fusion protein [Chlamydia psittaci Mat116]	24.48	433	266	17	163	563	3	406	6e-09	69.7
rs:WP_022415147	DNA topoisomerase [Dorea longicatena CAG:42].	22.93	532	321	21	7	504	6	482	6e-09	69.3
rs:WP_035463992	DNA topoisomerase I [Bartonella bacilliformis].	23.77	547	312	25	7	505	4	493	6e-09	69.7
rs:WP_022054850	DNA topoisomerase [Coprobacillus sp. CAG:605].	23.64	533	322	21	80	580	57	536	6e-09	69.3
rs:WP_025021506	hypothetical protein [Lactobacillus equi].	20.96	477	321	16	14	449	5	466	6e-09	68.9
rs:WP_010370160	DNA topoisomerase I [Weissella cibaria].	21.95	451	304	17	7	432	6	433	6e-09	69.3
tr:G9A4M7_RHIFH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.42	555	314	24	3	505	2	497	6e-09	69.7
rs:WP_035636833	DNA topoisomerase I [Flavobacterium sp. EM1308].	24.29	527	301	22	7	504	6	463	6e-09	69.7
rs:WP_008629835	DNA topoisomerase I [Mariniradius saccharolyticus].	24.87	386	230	13	7	389	6	334	6e-09	69.7
rs:WP_035005899	DNA topoisomerase I [Bartonella rochalimae].	25.60	457	264	22	97	505	65	493	6e-09	69.7
rs:WP_017731204	hypothetical protein [Nafulsella turpanensis].	22.30	556	356	19	38	563	20	529	6e-09	69.3
rs:WP_003502432	DNA topoisomerase I [Agrobacterium tumefaciens].	23.32	549	320	21	4	505	1	495	6e-09	69.7
rs:XP_006065664	PREDICTED: DNA topoisomerase 3-beta-1 [Bubalus bubalis].	26.51	298	166	15	273	553	279	540	6e-09	69.7
rs:WP_007531862	DNA topoisomerase I [Rhizobium mesoamericanum].	26.84	462	250	22	107	510	75	506	6e-09	69.7
rs:WP_043708741	DNA topoisomerase I [Weissella cibaria].	21.95	451	304	17	7	432	6	433	6e-09	69.3
rs:WP_045472181	DNA topoisomerase I [Winogradskyella sp. PG-2].	27.00	426	249	18	106	504	76	466	6e-09	69.3
gpu:CP009520_2425	DNA topoisomerase I [Methanosarcina vacuolata Z-761]	23.52	591	349	24	8	548	6	543	6e-09	69.3
rs:WP_022160764	DNA topoisomerase [Odoribacter splanchnicus CAG:14].	24.38	443	277	18	86	504	56	464	6e-09	69.3
rs:WP_022202470	DNA topoisomerase [Clostridium clostridioforme CAG:132].	23.18	440	294	15	93	504	63	486	6e-09	69.3
rs:WP_026788352	DNA topoisomerase I [Planktothrix rubescens].	23.39	573	331	19	46	566	29	545	6e-09	69.3
tr:E6VVS8_DESAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.37	522	333	19	7	505	6	483	7e-09	69.3
rs:WP_026644146	DNA topoisomerase I [Bifidobacterium pseudolongum].	20.71	560	332	19	7	505	8	516	7e-09	69.7
rs:WP_016230148	DNA topoisomerase I [Lachnospiraceae bacterium 10-1].	23.67	431	269	20	107	504	77	480	7e-09	69.3
rs:WP_029470217	DNA topoisomerase I [Clostridiales bacterium VE202-06].	23.61	449	276	19	93	504	63	481	7e-09	69.3
rs:WP_021975896	DNA topoisomerase [Ruminococcus sp. CAG:17].	23.64	440	277	17	97	504	67	479	7e-09	69.3
rs:WP_025955280	DNA topoisomerase I [Prochlorococcus sp. scB243_498I20].	24.95	513	300	19	101	579	85	546	7e-09	69.3
rs:WP_031533810	MULTISPECIES: DNA topoisomerase I [Bacteroides].	23.70	519	318	19	7	504	5	466	7e-09	69.3
rs:WP_025606038	DNA topoisomerase I [Pontibacter actiniarum].	23.33	433	262	16	7	431	6	376	7e-09	69.3
rs:WP_045992673	DNA topoisomerase I [Halomonas sp. S2151].	22.71	436	295	13	88	505	99	510	7e-09	69.3
rs:WP_010201217	DNA topoisomerase III, partial [Pseudomonas amygdali].	39.73	73	41	1	65	137	7	76	7e-09	63.9
rs:WP_005540121	DNA topoisomerase I [Johnsonella ignava].	24.27	445	272	17	97	505	67	482	7e-09	69.3
rs:WP_024835713	DNA topoisomerase I [Clostridium sp. 12(A)].	22.83	438	295	14	93	504	63	483	7e-09	69.3
rs:WP_023984273	DNA topoisomerase I [Prevotella oralis].	24.04	520	320	18	7	505	6	471	7e-09	69.3
rs:WP_006243846	DNA topoisomerase I [Mycobacterium tusciae].	23.57	471	288	16	86	504	82	532	7e-09	69.3
rs:WP_042401695	hypothetical protein [Geomicrobium sp. JCM 19037].	32.65	147	81	4	448	593	3	132	7e-09	67.0
tr:E6YLX8_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.60	457	264	22	97	505	65	493	7e-09	69.3
rs:WP_026798579	MULTISPECIES: DNA topoisomerase I [Planktothrix].	23.39	573	331	19	46	566	29	545	7e-09	69.3
tr:C2D5U8_LACBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.17	192	121	8	279	462	15	199	7e-09	66.2
rs:WP_012781804	DNA topoisomerase I [Flavobacteriaceae bacterium 3519-10].	22.90	524	312	22	7	504	6	463	7e-09	69.3
tr:A0A0D5U3L7_XANCI	SubName: Full=Topoisomerase IA {ECO:0000313|EMBL:AJZ44583.1};	29.23	130	72	2	441	552	14	141	7e-09	67.0
rs:WP_018919763	DNA topoisomerase I [Prevotella oris].	23.71	523	315	20	7	504	6	469	7e-09	69.3
tr:H2SPY9_TAKRU	SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTRUP00000014476};	23.21	474	282	19	112	553	117	540	7e-09	68.9
rs:WP_030088839	DNA topoisomerase I, partial [Streptomyces decoyicus].	25.53	380	226	14	97	440	91	449	7e-09	68.6
rs:WP_035325402	DNA topoisomerase I [Dokdonia donghaensis].	24.58	537	309	24	7	512	6	477	7e-09	69.3
rs:WP_041488845	DNA topoisomerase I, partial [Bacillus mycoides].	28.40	162	92	2	110	271	1	138	7e-09	65.5
rs:WP_029785268	DNA topoisomerase III, partial [Escherichia coli].	25.94	239	154	8	38	267	7	231	7e-09	66.2
rs:WP_026356103	DNA topoisomerase I [Pannonibacter phragmitetus].	26.99	352	204	17	107	430	75	401	7e-09	69.3
rs:WP_023418078	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.43	559	319	23	7	505	15	524	7e-09	69.3
rs:WP_026316472	DNA topoisomerase I [Actinokineospora enzanensis].	23.58	564	331	19	7	510	23	546	7e-09	69.3
rs:WP_026612485	DNA topoisomerase I [Ensifer sp. TW10].	23.69	553	312	25	4	505	1	494	7e-09	69.3
rs:WP_024295678	MULTISPECIES: DNA topoisomerase I [Lachnoclostridium].	22.30	444	290	14	93	504	63	483	8e-09	68.9
rs:WP_041872694	DNA topoisomerase III, partial [Verrucomicrobia bacterium SCGC AAA164-O14].	29.90	194	115	6	3	184	2	186	8e-09	65.9
rs:WP_038134722	DNA topoisomerase I [Thiomicrospira sp. Milos-T1].	22.67	516	327	17	7	505	5	465	8e-09	69.3
rs:WP_036324537	DNA topoisomerase I [Microbispora sp. ATCC PTA-5024].	21.92	552	336	20	7	505	14	523	8e-09	69.3
rs:WP_037383320	DNA topoisomerase I [Sinorhizobium americanum].	23.29	554	314	24	4	505	1	495	8e-09	69.3
rs:WP_012742655	DNA topoisomerase I [Eubacterium rectale].	24.64	556	332	23	7	540	6	496	8e-09	68.9
rs:WP_019036094	DNA topoisomerase I [Prevotella amnii].	23.93	535	305	21	7	504	6	475	8e-09	68.9
rs:WP_030477548	DNA topoisomerase I [Lentzea albidocapillata].	22.00	559	346	20	7	510	21	544	8e-09	69.3
rs:WP_022935662	DNA topoisomerase I [Mycoplasma moatsii].	22.63	570	352	24	7	549	5	512	8e-09	68.9
rs:WP_027486209	DNA topoisomerase I [Rhizobium undicola].	25.78	450	269	21	107	510	75	505	8e-09	69.3
rs:WP_033624172	hypothetical protein, partial [Enterococcus faecium].	31.25	128	84	2	108	234	1	125	8e-09	65.1
rs:WP_021614278	DNA topoisomerase I [Actinomyces sp. oral taxon 877].	21.89	571	333	18	1	505	1	524	8e-09	69.3
rs:WP_036853384	DNA topoisomerase I [Prevotella denticola].	23.15	527	320	18	7	505	6	475	8e-09	68.9
rs:WP_024838933	DNA topoisomerase I [Cellulosimicrobium cellulans].	21.75	570	335	20	7	505	6	535	8e-09	69.3
rs:WP_024541650	DNA topoisomerase I [Bifidobacterium choerinum].	21.27	569	335	22	7	510	8	528	8e-09	69.3
tr:X0SQS6_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_L06524 {ECO:0000313|EMBL:GAF77471.1}; Flags: Fragment;	25.83	302	181	9	7	304	4	266	8e-09	66.6
rs:WP_008976266	MULTISPECIES: DNA topoisomerase I [Coprococcus].	24.77	444	277	17	93	504	63	481	8e-09	68.9
rs:WP_041409512	DNA topoisomerase I [Sinorhizobium fredii].	23.47	554	313	24	4	505	1	495	8e-09	69.3
rs:WP_005683117	DNA topoisomerase I [Mycoplasma alligatoris].	21.19	538	330	16	7	510	6	483	8e-09	68.9
rs:WP_017192448	hypothetical protein [Milkweed yellows phytoplasma].	24.30	428	268	15	100	504	72	466	8e-09	68.9
rs:WP_034234041	DNA topoisomerase I [Lachnospiraceae bacterium AC2029].	22.60	531	316	21	7	504	6	474	8e-09	68.9
rs:WP_035390023	DNA topoisomerase I [Ferrimicrobium acidiphilum].	23.73	472	283	19	89	504	73	523	8e-09	68.9
rs:WP_020304538	DNA topoisomerase III [Pseudomonas syringae].	25.93	216	146	6	4	217	1	204	8e-09	66.2
sp:TOP1_MYCLE	RecName: Full=DNA topoisomerase 1 {ECO:0000255|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000255|HAMAP-Rule:MF_00952}; AltName: Full=Omega-protein; AltName: Full=Relaxing enzyme; AltName: Full=Swivelase; AltName: Full=Untwisting enzyme;	24.07	511	306	17	86	550	83	557	8e-09	69.3
rs:WP_043940599	DNA topoisomerase I [Weissella cibaria].	21.95	451	304	17	7	432	6	433	8e-09	68.9
tr:N6V4J9_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.59	469	268	22	97	510	66	508	8e-09	68.9
tr:F3GJ48_PSESJ	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGH47101.1}; Flags: Fragment;	36.46	96	59	1	356	449	182	277	8e-09	67.0
rs:WP_031545533	DNA topoisomerase I [Lachnospiraceae bacterium AC2014].	25.24	531	303	24	47	540	21	494	9e-09	68.9
rs:WP_036855184	DNA topoisomerase I [Prevotella amnii].	23.93	535	305	21	7	504	6	475	9e-09	68.9
rs:XP_011616870	PREDICTED: probable G-protein coupled receptor 144 [Takifugu rubripes].	23.21	474	282	19	112	553	117	540	9e-09	69.3
rs:WP_004373408	DNA topoisomerase I [Prevotella oris].	23.85	524	313	21	7	504	6	469	9e-09	68.9
rs:WP_037127390	DNA topoisomerase I [Rhizobium sp. CF394].	26.57	463	251	22	107	510	75	507	9e-09	68.9
rs:WP_008152743	hypothetical protein, partial [Parabacteroides johnsonii].	26.07	349	194	14	7	348	6	297	9e-09	67.8
rs:WP_013313691	DNA topoisomerase I [Spirochaeta thermophila].	23.45	533	322	21	2	504	10	486	9e-09	68.9
rs:WP_030698222	DNA topoisomerase I [Streptomyces griseus].	23.43	559	319	23	7	505	15	524	9e-09	68.9
rs:WP_025933212	DNA topoisomerase I [Prochlorococcus sp. scB243_498A3].	24.80	512	302	17	101	579	85	546	9e-09	68.9
tr:A0A090SK27_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL27228.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL27228.1};	31.16	138	88	2	416	548	2	137	9e-09	66.2
rs:WP_037080464	DNA topoisomerase I [Rhizobium vignae].	24.78	460	266	21	97	505	65	495	9e-09	68.9
rs:WP_037153652	DNA topoisomerase I [Rhizobium freirei].	25.59	469	268	22	97	510	65	507	9e-09	68.9
rs:XP_011953620	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Ovis aries].	26.58	301	179	17	216	498	227	503	9e-09	68.9
rs:WP_012162550	DNA topoisomerase I [Acaryochloris marina].	23.50	549	335	18	65	579	48	545	9e-09	68.9
rs:WP_006803964	DNA topoisomerase I [Leptotrichia hofstadii].	22.18	532	314	18	7	504	6	471	9e-09	68.9
rs:WP_004369289	DNA topoisomerase I [Prevotella oralis].	24.23	520	319	18	7	505	6	471	9e-09	68.9
rs:WP_033142381	DNA topoisomerase I [Blautia producta].	23.61	449	276	19	93	504	63	481	9e-09	68.9
rs:WP_047139490	DNA topoisomerase I [Streptomyces sp. KE1].	23.43	559	319	23	7	505	15	524	9e-09	68.9
tr:K1RMM9_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC44784.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC44784.1}; Flags: Fragment;	26.69	236	147	6	285	503	20	246	9e-09	66.2
rs:WP_039844588	DNA topoisomerase I [Rhizobium gallicum].	26.43	454	262	23	107	510	75	506	1e-08	68.9
rs:XP_002597412	hypothetical protein BRAFLDRAFT_80591 [Branchiostoma floridae].	25.08	295	191	12	216	498	226	502	1e-08	68.9
rs:WP_041322328	DNA topoisomerase I [Mycobacterium leprae].	24.27	482	291	17	86	510	89	553	1e-08	68.9
rs:WP_027638117	DNA topoisomerase I [Clostridium cadaveris].	23.81	525	323	18	7	505	6	479	1e-08	68.9
rs:WP_028787284	DNA topoisomerase I [Terrimonas ferruginea].	24.23	392	231	12	7	389	6	340	1e-08	68.9
rs:WP_044261256	DNA topoisomerase I, partial [Candidatus Prevotella conceptionensis].	27.27	209	134	4	43	243	8	206	1e-08	65.9
rs:WP_011375995	DNA topoisomerase I [Prochlorococcus marinus].	24.22	512	305	16	101	579	85	546	1e-08	68.9
rs:WP_002583384	MULTISPECIES: DNA topoisomerase I [Clostridiales].	23.13	441	295	15	93	505	63	487	1e-08	68.6
tr:M0V3B7_HORVD	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:MLOC_17646.3};	22.75	611	368	28	30	599	18	565	1e-08	68.9
rs:WP_026749247	DNA topoisomerase I [Leptotrichia trevisanii].	22.37	523	324	18	7	504	6	471	1e-08	68.9
rs:WP_044145816	DNA topoisomerase I, partial [Enterococcus faecium].	23.76	526	322	18	7	504	7	481	1e-08	68.6
rs:WP_029959672	DNA topoisomerase I [Ensifer sp. USDA 6670].	23.10	554	315	24	4	505	1	495	1e-08	68.9
rs:WP_007626156	DNA topoisomerase I [Rhizobium sp. CCGE 510].	25.88	456	262	22	107	510	75	506	1e-08	68.9
rs:WP_017933258	DNA topoisomerase I [Nocardioides sp. Iso805N].	23.79	559	337	23	89	597	73	592	1e-08	68.9
rs:WP_028283498	DNA topoisomerase I [Olleya marilimosa].	26.65	334	191	11	7	336	6	289	1e-08	68.9
rs:WP_033609400	topoisomerase I, partial [Lactobacillus plantarum].	30.41	148	84	4	200	339	1	137	1e-08	65.5
rs:WP_022299282	DNA topoisomerase [Clostridium sp. CAG:964].	22.97	627	367	27	7	595	5	553	1e-08	68.6
rs:WP_002336210	hypothetical protein, partial [Enterococcus faecium].	30.56	144	93	4	52	192	2	141	1e-08	65.1
rs:WP_037414251	DNA topoisomerase I [Sinorhizobium sp. CCBAU 05631].	23.47	554	313	24	4	505	1	495	1e-08	68.9
rs:WP_025894079	DNA topoisomerase I, partial [Prochlorococcus sp. scB243_497J18].	26.29	426	259	16	107	498	64	468	1e-08	68.2
rs:WP_033239415	DNA topoisomerase I [Streptomyces griseus].	23.43	559	319	23	7	505	15	524	1e-08	68.9
rs:WP_031178411	DNA topoisomerase I [Streptomyces sp. NRRL B-3253].	23.43	559	319	23	7	505	15	524	1e-08	68.9
rs:WP_018470360	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.43	559	319	23	7	505	15	524	1e-08	68.9
rs:WP_003949667	MULTISPECIES: DNA topoisomerase I [Streptomyces].	23.43	559	319	23	7	505	15	524	1e-08	68.9
rs:WP_030309838	DNA topoisomerase I [Streptomyces albidoflavus].	23.43	559	319	23	7	505	15	524	1e-08	68.9
rs:WP_025967891	DNA topoisomerase I [Prochlorococcus sp. scB245a_518I6].	24.95	513	300	19	101	579	85	546	1e-08	68.9
rs:XP_002140607	DNA topoisomerase family protein [Cryptosporidium muris RN66].	20.42	573	387	21	7	553	33	562	1e-08	68.9
rs:WP_034085616	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	23.45	354	223	11	217	553	3	325	1e-08	68.2
rs:WP_014624573	DNA topoisomerase I [Spirochaeta thermophila].	23.40	530	320	21	5	504	13	486	1e-08	68.6
tr:A0A0B7CZP6_9PSEU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|RuleBase:RU000518}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.20	545	344	18	7	504	44	555	1e-08	68.9
rs:WP_036868463	DNA topoisomerase I, partial [Prevotella bivia].	26.32	209	131	5	4	204	2	195	1e-08	65.5
rs:WP_009262778	DNA topoisomerase I [Lachnospiraceae bacterium 9_1_43BFAA].	24.55	444	278	17	93	504	63	481	1e-08	68.6
tr:A0A0E0IGT1_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA09G02300.2};	23.13	588	347	25	8	546	67	598	1e-08	68.9
rs:WP_028735946	DNA topoisomerase I [Rhizobium selenitireducens].	26.13	444	260	20	107	505	75	495	1e-08	68.9
rs:WP_025880728	DNA topoisomerase I [Prochlorococcus sp. scB241_527E14].	25.15	513	299	20	101	579	85	546	1e-08	68.6
rs:WP_025931465	MULTISPECIES: DNA topoisomerase I [Prochlorococcus].	25.15	513	299	18	101	579	85	546	1e-08	68.6
rs:WP_039341893	DNA topoisomerase I [Chryseobacterium solincola].	22.03	522	319	22	7	504	6	463	1e-08	68.6
rs:WP_008678395	DNA topoisomerase I [Clostridium sp. 7_2_43FAA].	24.10	527	319	21	7	505	6	479	1e-08	68.6
rs:WP_012539201	DNA topoisomerase I [Borrelia recurrentis].	23.55	603	345	26	7	561	7	541	1e-08	68.6
rs:WP_026291530	DNA topoisomerase I [Marinobacterium rhizophilum].	23.64	440	285	17	99	512	108	522	1e-08	68.6
rs:WP_037563180	hypothetical protein [Spirochaeta sp. JC202].	22.81	548	331	22	7	510	2	501	1e-08	68.6
rs:WP_047097084	DNA topoisomerase I [Chryseobacterium indologenes].	22.24	526	313	23	7	504	6	463	1e-08	68.6
rs:WP_034438725	DNA topoisomerase I [Candidatus Clostridium anorexicamassiliense].	23.33	523	328	17	7	504	6	480	1e-08	68.6
rs:WP_009538494	DNA topoisomerase I [Caenispirillum salinarum].	25.46	538	311	24	7	505	4	490	1e-08	68.6
rs:WP_034570232	hypothetical protein [Helicobacter sanguini].	24.31	432	256	17	107	505	71	464	1e-08	68.6
rs:WP_042317180	DNA topoisomerase III, partial [Desulfotomaculum acetoxidans].	33.85	130	74	5	441	561	3	129	1e-08	67.4
rs:WP_004028404	DNA topoisomerase I [Spiroplasma melliferum].	22.18	523	328	18	5	504	4	470	1e-08	68.6
rs:WP_022329931	DNA topoisomerase [Firmicutes bacterium CAG:313].	26.79	433	254	19	107	504	78	482	1e-08	68.6
rs:WP_006942643	DNA topoisomerase I [Megasphaera micronuciformis].	22.95	536	318	22	7	504	57	535	1e-08	68.6
rs:WP_035879967	DNA topoisomerase I, partial [Cryobacterium sp. MLB-32].	22.76	558	336	19	7	505	8	529	1e-08	68.6
rs:WP_022369374	DNA topoisomerase [Firmicutes bacterium CAG:882].	23.76	442	284	19	93	504	63	481	1e-08	68.6
tr:I1BYY5_RHIO9	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.09	516	300	21	10	498	16	456	1e-08	68.6
rs:WP_027673005	DNA topoisomerase I [Agrobacterium larrymoorei].	26.79	448	252	23	107	505	75	495	1e-08	68.6
rs:WP_018966719	DNA topoisomerase I [Prevotella loescheii].	24.05	578	340	21	7	552	6	516	1e-08	68.6
rs:WP_042198471	DNA topoisomerase I, partial [Kibdelosporangium sp. MJ126-NF4].	22.20	545	344	18	7	504	2	513	1e-08	68.6
rs:WP_023260375	DNA topoisomerase III, partial [Salmonella enterica].	28.17	142	95	2	416	552	2	141	1e-08	65.9
rs:WP_034438608	DNA topoisomerase I [Clostridiales bacterium S5-A11].	24.57	529	313	20	7	504	5	478	1e-08	68.2
rs:WP_004029070	DNA topoisomerase I [Spiroplasma melliferum].	22.18	523	328	18	5	504	4	470	1e-08	68.2
rs:WP_018325938	DNA topoisomerase I [Rhizobium giardinii].	24.56	562	313	27	4	510	1	506	1e-08	68.6
rs:WP_029069541	DNA topoisomerase I [Jonesia quinghaiensis].	22.75	567	318	24	7	505	8	522	1e-08	68.6
rs:WP_025956525	DNA topoisomerase I [Prochlorococcus sp. scB243_498L10].	25.05	507	295	19	107	579	91	546	1e-08	68.6
rs:WP_026619340	DNA topoisomerase I [Ensifer sp. WSM1721].	23.51	553	313	25	4	505	1	494	1e-08	68.6
rs:WP_018202630	hypothetical protein, partial [Parcubacteria bacterium SCGC AAA011-J21].	27.67	253	161	8	269	504	4	251	1e-08	68.2
rs:WP_036870289	DNA topoisomerase I [Prevotella histicola].	24.58	537	298	23	7	504	6	474	1e-08	68.6
rs:WP_020403880	hypothetical protein [Gracilimonas tropica].	25.85	441	267	19	107	505	90	512	1e-08	68.6
tr:U2SE50_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.35	471	283	17	89	505	76	522	1e-08	68.6
rs:WP_002983696	DNA topoisomerase I [Chryseobacterium gleum].	21.82	527	314	24	7	504	6	463	1e-08	68.6
rs:WP_017193621	hypothetical protein [Vaccinium witches'-broom phytoplasma].	23.83	428	270	15	100	504	72	466	1e-08	68.2
rs:WP_005942398	MULTISPECIES: DNA topoisomerase I [Bacteroides].	22.48	516	330	19	7	504	6	469	1e-08	68.2
rs:WP_024289852	DNA topoisomerase I [Microbacterium sp. KROCY2].	23.12	558	338	18	2	505	8	528	1e-08	68.6
rs:WP_034489568	DNA topoisomerase I [Agrobacterium rhizogenes].	26.36	459	257	22	107	510	75	507	1e-08	68.6
tr:W1FZV9_ECOLX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDL39904.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDL39904.1};	31.97	122	76	2	436	552	9	128	1e-08	65.5
tr:A0A072CGV2_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.00	448	260	20	107	505	70	490	1e-08	68.6
rs:WP_007367631	DNA topoisomerase I [Prevotella multiformis].	23.11	528	317	16	7	504	6	474	1e-08	68.2
rs:WP_041677855	DNA topoisomerase I [Rhizobium tropici].	25.75	466	270	21	97	510	65	506	1e-08	68.6
tr:A0A024GTK3_9STRA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.73	629	395	25	7	593	6	585	1e-08	68.6
rs:WP_002564492	DNA topoisomerase I [[Clostridium] bolteae].	23.18	440	294	15	93	504	63	486	1e-08	68.2
rs:WP_007844344	MULTISPECIES: DNA topoisomerase I [Chryseobacterium].	21.99	523	318	22	7	504	6	463	1e-08	68.2
tr:I3X7P4_RHIFR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.97	559	306	26	3	505	2	497	1e-08	68.2
rs:WP_017588254	DNA topoisomerase I [Nocardiopsis ganjiahuensis].	24.64	548	329	21	7	505	26	538	1e-08	68.6
rs:WP_032953621	DNA topoisomerase I, partial [Bacteroides vulgatus].	25.00	208	142	3	97	304	3	196	1e-08	65.1
rs:WP_020012348	MULTISPECIES: DNA topoisomerase I [Agrobacterium].	23.13	549	321	21	4	505	1	495	1e-08	68.2
rs:WP_026414122	DNA topoisomerase I [Actinomadura oligospora].	21.18	543	350	14	7	505	22	530	1e-08	68.2
rs:WP_014143594	DNA topoisomerase I [Streptomyces cattleya].	24.08	461	275	18	97	505	89	526	1e-08	68.6
rs:WP_006213774	DNA topoisomerase I [Kocuria palustris].	23.12	558	338	18	2	505	8	528	2e-08	68.2
rs:WP_010643779	DNA topoisomerase I [Streptomyces sp. S4].	23.38	556	323	23	7	505	15	524	2e-08	68.2
tr:A0A024GSI2_9STRA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.73	629	395	25	7	593	1	580	2e-08	68.2
rs:WP_002309561	DNA topoisomerase I [Enterococcus faecium].	23.68	532	327	18	1	504	1	481	2e-08	68.2
tr:L0LHC8_RHITR	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.75	466	270	21	97	510	67	508	2e-08	68.2
tr:X1IK14_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S14558 {ECO:0000313|EMBL:GAH69600.1};	33.53	170	99	5	38	206	19	175	2e-08	65.1
rs:WP_043120466	DNA topoisomerase I, partial [Propionibacterium acidifaciens].	23.35	471	283	17	89	505	76	522	2e-08	68.2
tr:X1LXD9_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S08239 {ECO:0000313|EMBL:GAI23743.1}; Flags: Fragment;	24.64	280	178	9	278	552	6	257	2e-08	65.9
rs:XP_002770630	DEHA2G13376p [Debaryomyces hansenii CBS767].	22.85	582	348	25	7	543	3	528	2e-08	67.8
rs:WP_036897368	DNA topoisomerase I [Prochlorococcus marinus].	24.17	513	304	18	101	579	85	546	2e-08	68.2
rs:WP_022462183	DNA topoisomerase [Blautia sp. CAG:37].	22.59	456	274	16	93	505	63	482	2e-08	68.2
rs:WP_029783752	DNA topoisomerase I, partial [Leptospira interrogans].	23.75	421	272	15	107	505	6	399	2e-08	67.8
tr:K1YKP6_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKD37696.1}; Flags: Fragment;	29.95	197	125	7	1	191	1	190	2e-08	65.1
rs:WP_033422723	hypothetical protein, partial [Empedobacter brevis].	26.94	219	145	7	278	487	59	271	2e-08	67.4
rs:WP_000772479	DNA topoisomerase I [Acinetobacter baumannii].	24.33	485	294	22	46	504	28	465	2e-08	67.8
rs:WP_046792747	DNA topoisomerase I [Rhizobium sp. LC145].	25.51	443	264	21	107	505	75	495	2e-08	68.2
rs:WP_025946641	DNA topoisomerase I [Prochlorococcus sp. scB241_528N20].	24.95	513	300	19	101	579	85	546	2e-08	68.2
rs:WP_002290218	DNA topoisomerase I [Enterococcus faecium].	23.76	526	322	18	7	504	7	481	2e-08	68.2
rs:WP_013386983	DNA topoisomerase I [Ilyobacter polytropus].	22.01	577	347	21	1	553	1	498	2e-08	68.2
tr:D2PW45_KRIFD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.20	545	342	17	7	505	23	531	2e-08	68.2
rs:WP_023508917	DNA topoisomerase I [Sporolactobacillus laevolacticus].	25.00	432	256	17	112	504	82	484	2e-08	68.2
rs:WP_031915413	DNA topoisomerase III, partial [Staphylococcus aureus].	28.10	153	105	3	411	559	1	152	2e-08	66.6
rs:WP_045715532	DNA topoisomerase III, partial [Salmonella enterica].	28.77	146	95	5	8	151	5	143	2e-08	64.7
tr:A0A009GGC7_ACIBA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	24.53	428	244	17	7	403	25	404	2e-08	67.4
rs:WP_025962241	DNA topoisomerase I [Prochlorococcus sp. scB245a_521K15].	25.15	513	299	20	101	579	85	546	2e-08	68.2
rs:WP_002345057	DNA topoisomerase 1 [Enterococcus faecium].	23.76	526	322	18	7	504	7	481	2e-08	68.2
rs:WP_021875555	DNA topoisomerase [Clostridium chauvoei].	23.54	531	317	20	7	505	6	479	2e-08	68.2
rs:WP_003496397	DNA topoisomerase I [Agrobacterium tumefaciens].	23.41	551	317	22	4	505	1	495	2e-08	68.2
tr:S4EF11_ENTFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.76	526	322	18	7	504	25	499	2e-08	68.2
rs:WP_025913466	MULTISPECIES: DNA topoisomerase I [Prochlorococcus].	25.05	507	295	19	107	579	91	546	2e-08	68.2
rs:WP_025929208	DNA topoisomerase I [Prochlorococcus sp. scB243_496A2].	25.05	507	295	19	107	579	91	546	2e-08	68.2
rs:WP_005331658	DNA topoisomerase I [Dorea formicigenerans].	22.39	527	329	21	7	504	6	481	2e-08	68.2
rs:WP_031426006	DNA topoisomerase I [Leeuwenhoekiella sp. MAR_2009_132].	23.93	535	315	22	7	512	6	477	2e-08	68.2
rs:WP_034030776	hypothetical protein, partial [Pseudomonas aeruginosa].	35.04	117	68	3	8	124	5	113	2e-08	63.9
tr:A0A0C3PNK5_PISTI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.88	537	310	28	7	498	3	496	2e-08	68.2
rs:WP_025922213	MULTISPECIES: DNA topoisomerase I [Prochlorococcus].	25.05	507	295	19	107	579	91	546	2e-08	68.2
rs:WP_025975307	DNA topoisomerase I [Prochlorococcus sp. scB243_495K23].	25.05	507	295	19	107	579	91	546	2e-08	68.2
rs:WP_042832025	DNA topoisomerase III, partial [Xanthomonas citri].	32.35	102	67	1	451	552	27	126	2e-08	65.5
rs:WP_015071551	DNA topoisomerase [Propionibacterium acidipropionici].	23.42	474	288	17	86	505	72	524	2e-08	68.2
rs:WP_008705704	MULTISPECIES: DNA topoisomerase I [Clostridiales].	23.49	430	270	16	107	504	77	479	2e-08	67.8
rs:WP_009744288	DNA topoisomerase I [Actinomyces sp. oral taxon 178].	21.89	571	333	18	1	505	1	524	2e-08	68.2
tr:J6ZEN4_ENTFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.76	526	322	18	7	504	25	499	2e-08	67.8
rs:WP_025478161	DNA topoisomerase I [Enterococcus faecium].	23.76	526	322	18	7	504	7	481	2e-08	67.8
rs:WP_021105143	DNA topoisomerase I [Propionibacterium granulosum].	23.13	467	288	18	89	505	75	520	2e-08	68.2
rs:WP_034854032	DNA topoisomerase I [Ensifer sojae].	23.29	554	314	24	4	505	1	495	2e-08	68.2
rs:WP_010730456	DNA topoisomerase 1 [Enterococcus faecium].	23.76	526	322	18	7	504	7	481	2e-08	67.8
tr:D2JTF8_STAAU	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ADA54521.1}; Flags: Fragment;	32.48	117	74	3	447	559	26	141	2e-08	64.3
rs:WP_025579645	DNA topoisomerase I [Blautia wexlerae].	23.49	430	270	16	107	504	77	479	2e-08	67.8
rs:XP_005370069	PREDICTED: DNA topoisomerase 3-beta-1 [Microtus ochrogaster].	25.68	296	167	15	275	553	281	540	2e-08	68.2
tr:J8Z6D6_ENTFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.76	526	322	18	7	504	25	499	2e-08	67.8
rs:WP_024982273	DNA topoisomerase I [Flavobacterium succinicans].	23.66	524	308	21	7	504	6	463	2e-08	68.2
rs:WP_010491173	topoisomerase IA, partial [Lactobacillus zeae].	29.31	174	106	6	402	563	22	190	2e-08	66.6
rs:WP_025964631	DNA topoisomerase I [Prochlorococcus sp. scB243_498P15].	25.05	507	295	19	107	579	91	546	2e-08	68.2
rs:WP_002313870	DNA topoisomerase I [Enterococcus faecium].	23.76	526	322	18	7	504	7	481	2e-08	67.8
rs:WP_035217622	DNA topoisomerase I [Agrobacterium tumefaciens].	23.40	547	322	22	4	505	1	495	2e-08	68.2
rs:WP_013128447	DNA topoisomerase I [Tsukamurella paurometabola].	23.40	594	345	20	7	550	17	550	2e-08	68.2
tr:L3QGS2_ECOLX	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELE59473.1};	46.03	63	34	0	477	539	2	64	2e-08	63.9
rs:WP_032118150	DNA topoisomerase I [Clostridium sp. CL-2].	25.00	528	313	23	7	505	6	479	2e-08	67.8
rs:WP_007560043	DNA topoisomerase I [Bacteroides plebeius].	22.80	522	316	20	7	504	6	464	2e-08	67.8
tr:C2HAA3_ENTFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.76	526	322	18	7	504	25	499	2e-08	67.8
rs:WP_025940181	MULTISPECIES: DNA topoisomerase I [Prochlorococcus].	24.95	513	300	18	101	579	85	546	2e-08	67.8
rs:WP_037349093	DNA topoisomerase I, partial [Anaplasma marginale].	25.70	358	215	15	4	347	1	321	2e-08	66.6
gpu:CP009314_105	DNA topoisomerase family protein [Bacillus anthracis str. Turkey32]	30.77	143	87	4	101	238	1	136	2e-08	64.3
tr:A0A061NPP8_9BACL	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAK04500.1};	34.09	132	70	3	462	593	12	126	2e-08	65.5
rs:WP_041289732	DNA topoisomerase I [Kribbella flavida].	22.20	545	342	17	7	505	1	509	2e-08	67.8
rs:WP_043119530	DNA topoisomerase I [Sinomonas sp. MUSC 117].	23.13	562	331	21	7	505	12	535	2e-08	67.8
rs:WP_025960305	DNA topoisomerase I [Prochlorococcus sp. scB245a_519E23].	24.95	513	300	19	101	579	85	546	2e-08	67.8
rs:WP_038398842	DNA topoisomerase I [Enterococcus faecium].	23.76	526	322	18	7	504	7	481	2e-08	67.8
rs:WP_039228825	MULTISPECIES: DNA topoisomerase I [Clostridium].	23.26	546	330	23	7	517	6	497	2e-08	67.8
rs:XP_004323500	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 3-beta-1-like [Tursiops truncatus].	25.84	298	168	15	273	553	267	528	2e-08	67.8
rs:WP_022502718	DNA topoisomerase [Eubacterium sp. CAG:76].	25.81	492	299	22	47	504	21	480	2e-08	67.8
rs:WP_002327967	DNA topoisomerase 1 [Enterococcus faecium].	23.76	526	322	18	7	504	7	481	2e-08	67.8
rs:WP_044280501	DNA topoisomerase I [Bifidobacterium thermophilum].	21.72	571	331	21	7	505	8	534	2e-08	67.8
rs:WP_025959683	DNA topoisomerase I [Prochlorococcus sp. scB245a_519C7].	25.05	507	295	19	107	579	91	546	2e-08	67.8
rs:WP_009878119	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	27.13	258	159	10	107	355	1	238	2e-08	65.5
rs:WP_010420670	DNA topoisomerase I [Anaerophaga thermohalophila].	22.89	533	317	21	1	504	7	474	2e-08	67.8
rs:WP_025887608	DNA topoisomerase I [Prochlorococcus sp. scB241_526B17].	24.95	513	300	19	101	579	85	546	2e-08	67.8
rs:WP_024961841	DNA topoisomerase I, partial [Campylobacter ureolyticus].	23.28	421	266	13	147	548	6	388	2e-08	67.4
rs:WP_025891467	MULTISPECIES: DNA topoisomerase I [Prochlorococcus].	24.95	513	300	19	101	579	85	546	2e-08	67.8
rs:WP_044626838	DNA topoisomerase I [Tamlana nanhaiensis].	24.24	524	305	22	7	504	6	463	2e-08	67.8
rs:WP_020479433	DNA topoisomerase I [Sinorhizobium meliloti].	23.57	560	307	26	4	505	1	497	2e-08	67.8
rs:WP_025974485	DNA topoisomerase I [Prochlorococcus sp. scB241_529J16].	24.95	513	300	19	101	579	85	546	2e-08	67.8
rs:WP_002320952	DNA topoisomerase I [Enterococcus faecium].	23.76	526	322	18	7	504	25	499	2e-08	67.8
rs:WP_007209260	MULTISPECIES: topoisomerase [Bacilli].	31.45	124	81	2	108	230	1	121	2e-08	63.5
rs:WP_029701702	DNA topoisomerase I [Clostridium sp. ASBs410].	23.71	447	280	17	93	504	63	483	2e-08	67.8
tr:A0A076GWJ3_ENTFC	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.76	526	322	18	7	504	25	499	2e-08	67.8
rs:WP_019968915	DNA topoisomerase I [Prevotella maculosa].	25.06	431	265	16	7	433	6	382	2e-08	67.8
rs:WP_026524285	DNA topoisomerase I [Butyrivibrio sp. MB2005].	24.27	445	279	20	93	504	66	485	2e-08	67.8
rs:XP_005107460	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Aplysia californica].	22.25	427	280	17	97	498	101	500	2e-08	67.8
rs:WP_008565877	DNA topoisomerase I [Prevotella maculosa].	25.06	431	265	16	7	433	6	382	2e-08	67.8
rs:WP_026669942	DNA topoisomerase I [Butyrivibrio sp. AE3006].	24.27	445	279	20	93	504	66	485	2e-08	67.4
rs:WP_025958268	DNA topoisomerase I [Prochlorococcus sp. scB241_527L15].	24.95	513	300	19	101	579	85	546	2e-08	67.8
rs:WP_014934419	DNA topoisomerase I [Cardinium endosymbiont of Encarsia pergandiella].	23.77	551	322	21	7	539	6	476	2e-08	67.8
tr:S2J5T0_MUCC1	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.08	650	413	25	7	607	8	606	2e-08	67.8
rs:WP_025953492	DNA topoisomerase I [Prochlorococcus sp. scB243_497N18].	24.95	513	300	19	101	579	85	546	2e-08	67.8
rs:WP_043658560	DNA topoisomerase I [Cellulosimicrobium cellulans].	21.54	571	336	20	7	505	6	536	2e-08	67.8
rs:WP_017959963	DNA topoisomerase I [Rhizobium leguminosarum].	26.01	469	245	25	107	510	75	506	2e-08	67.8
rs:WP_025954428	DNA topoisomerase I [Prochlorococcus sp. scB243_498C16].	24.95	513	300	19	101	579	85	546	2e-08	67.8
rs:WP_022281084	DNA topoisomerase [Clostridium sp. CAG:448].	22.62	535	325	20	7	504	5	487	2e-08	67.8
rs:WP_025940464	DNA topoisomerase I [Prochlorococcus sp. scB245a_518K17].	24.95	513	300	19	101	579	85	546	2e-08	67.8
rs:WP_010727828	DNA topoisomerase 1 [Enterococcus faecium].	23.76	526	322	18	7	504	7	481	2e-08	67.4
rs:WP_033150319	DNA topoisomerase I [Prevotella sp. RM4].	23.06	529	312	24	7	505	6	469	2e-08	67.8
rs:WP_033489090	DNA topoisomerase I [Bifidobacterium pseudolongum].	21.73	566	319	23	7	505	8	516	2e-08	67.8
rs:WP_002288411	MULTISPECIES: DNA topoisomerase I [Enterococcus].	23.76	526	322	18	7	504	7	481	2e-08	67.4
rs:WP_002339402	DNA topoisomerase 1 [Enterococcus faecium].	23.76	526	322	18	7	504	7	481	2e-08	67.4
rs:WP_025959372	DNA topoisomerase I [Prochlorococcus sp. scB241_527I9].	24.22	512	305	16	101	579	85	546	2e-08	67.8
rs:WP_003125270	topoisomerase I - like protein, partial [Pseudomonas aeruginosa].	27.27	286	171	13	86	355	58	322	2e-08	66.2
rs:WP_025980250	DNA topoisomerase I, partial [Prochlorococcus sp. scB243_498F21].	25.05	507	295	19	107	579	68	523	2e-08	67.8
rs:WP_029485243	DNA topoisomerase I [Enterococcus faecium].	23.76	526	322	18	7	504	7	481	2e-08	67.4
rs:WP_026494468	DNA topoisomerase I [Butyrivibrio sp. WCD3002].	24.27	445	279	20	93	504	66	485	2e-08	67.4
rs:WP_011264602	DNA topoisomerase I [Mycoplasma mobile].	22.63	548	317	20	7	518	6	482	2e-08	67.4
tr:K1S5B8_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC50674.1}; Flags: Fragment;	26.46	189	123	6	204	387	4	181	2e-08	64.3
rs:WP_044495900	DNA topoisomerase I, partial [Peptoclostridium difficile].	27.02	322	190	13	5	322	4	284	2e-08	65.5
rs:WP_016629581	hypothetical protein, partial [Enterococcus faecium].	32.20	118	76	2	108	224	1	115	2e-08	63.5
rs:WP_041415332	DNA topoisomerase I [Sinorhizobium fredii].	24.19	558	304	26	4	505	1	495	2e-08	67.8
rs:WP_004354064	DNA topoisomerase I [Prevotella denticola].	23.28	524	321	16	7	504	6	474	2e-08	67.4
rs:WP_034525093	hypothetical protein [Bacteroides propionicifaciens].	27.89	190	122	4	5	186	3	185	3e-08	64.7
rs:XP_008840414	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Nannospalax galili].	25.84	298	168	15	273	553	279	540	3e-08	67.4
rs:WP_027508567	DNA topoisomerase I [Rhizobium sullae].	26.30	460	255	22	107	510	75	506	3e-08	67.4
rs:WP_028909395	DNA topoisomerase I [Prevotella sp. AGR2160].	24.57	525	306	22	7	504	6	467	3e-08	67.4
tr:H1Q1U3_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.68	532	310	19	7	504	25	494	3e-08	67.4
tr:A0A024GSX9_9STRA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.58	629	398	24	7	593	1	582	3e-08	67.4
rs:XP_008840420	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Nannospalax galili].	25.84	298	168	15	273	553	274	535	3e-08	67.4
rs:WP_015618537	DNA topoisomerase I [Actinoplanes sp. N902-109].	23.30	575	324	26	7	512	11	537	3e-08	67.4
rs:WP_024732755	DNA topoisomerase I [Clostridiales bacterium VE202-14].	25.22	448	270	21	93	504	63	481	3e-08	67.4
rs:WP_003521492	DNA topoisomerase I subunit omega [Agrobacterium tumefaciens].	23.41	551	317	22	4	505	1	495	3e-08	67.4
rs:WP_022166320	DNA topoisomerase [Eubacterium sp. CAG:192].	25.00	208	110	5	370	532	10	216	3e-08	65.9
rs:XP_008333802	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Cynoglossus semilaevis].	22.20	473	298	18	107	553	112	540	3e-08	67.4
rs:WP_020921025	DNA topoisomerase 1 [Rhizobium etli].	25.64	468	268	22	97	510	65	506	3e-08	67.4
rs:WP_009435473	DNA topoisomerase I [Prevotella sp. oral taxon 306].	25.69	436	252	17	7	431	6	380	3e-08	67.4
tr:A0A024GSB7_9STRA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.58	629	398	24	7	593	6	587	3e-08	67.4
rs:WP_018572256	DNA topoisomerase I [Prevotella micans].	23.68	532	310	19	7	504	6	475	3e-08	67.4
tr:A0A0B0HLX4_9BACI	SubName: Full=DNA topoisomerase 3 {ECO:0000313|EMBL:KHF29597.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHF29597.1};	28.98	176	109	5	4	171	1	168	3e-08	63.9
tr:R9CB07_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EOR24346.1};	30.67	163	91	5	386	546	23	165	3e-08	66.2
rs:WP_022374432	DNA topoisomerase [Firmicutes bacterium CAG:270].	23.97	534	311	26	7	504	6	480	3e-08	67.4
tr:X7ZVZ0_MYCXE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.76	284	172	10	86	345	13	284	3e-08	66.6
rs:XP_012671463	PREDICTED: DNA topoisomerase 3-beta-1 [Clupea harengus].	24.75	295	171	13	275	553	281	540	3e-08	67.4
rs:XP_004574243	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Maylandia zebra].	21.69	590	362	24	7	553	6	538	3e-08	67.4
rs:WP_014773067	DNA topoisomerase I [Belliella baltica].	22.86	525	316	21	7	505	6	467	3e-08	67.4
rs:WP_043041427	MULTISPECIES: DNA topoisomerase I [Acinetobacter].	23.75	400	234	14	192	553	157	523	3e-08	67.4
tr:D5EXD2_PRER2	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.06	529	312	24	7	505	6	469	3e-08	67.4
rs:WP_040343002	DNA topoisomerase III, partial [Bacillus nealsonii].	30.67	163	91	5	386	546	20	162	3e-08	66.2
rs:WP_012858472	DNA topoisomerase I [Streptobacillus moniliformis].	22.06	553	316	23	7	515	6	487	3e-08	67.4
rs:WP_038281690	DNA topoisomerase I [[Clostridium] celerecrescens].	23.60	445	283	17	93	504	63	483	3e-08	67.4
rs:WP_036190436	DNA topoisomerase I [Marinobacterium sp. AK27].	21.18	543	369	16	5	512	4	522	3e-08	67.4
rs:XP_004276082	PREDICTED: DNA topoisomerase 3-beta-1 [Orcinus orca].	25.84	298	168	15	273	553	279	540	3e-08	67.4
rs:WP_044402915	DNA topoisomerase I [Lacinutrix sp. Hel_I_90].	24.71	518	310	19	7	504	6	463	3e-08	67.4
rs:WP_032513341	DNA topoisomerase I [Prochlorococcus marinus].	25.29	510	302	19	101	579	85	546	3e-08	67.4
rs:WP_025067094	DNA topoisomerase I [Prevotella denticola].	23.38	526	318	18	7	504	6	474	3e-08	67.4
rs:WP_002573299	DNA topoisomerase I [[Clostridium] bolteae].	23.18	440	294	15	93	504	63	486	3e-08	67.4
rs:WP_007162385	topoisomerase I [Pseudomonas psychrotolerans].	22.64	424	289	13	99	505	102	503	3e-08	67.4
rs:WP_002298115	DNA topoisomerase I [Enterococcus faecium].	23.76	526	322	18	7	504	7	481	3e-08	67.0
rs:WP_025906401	MULTISPECIES: DNA topoisomerase I [Prochlorococcus].	24.61	512	303	17	101	579	85	546	3e-08	67.4
rs:WP_012877128	DNA topoisomerase I [Xylanimonas cellulosilytica].	22.78	575	331	25	7	510	6	538	3e-08	67.4
rs:WP_006710035	DNA topoisomerase, partial [Serratia symbiotica].	29.19	185	116	8	34	214	1	174	3e-08	64.3
rs:WP_031233433	DNA topoisomerase I [Agrobacterium tumefaciens].	23.41	551	317	22	4	505	1	495	3e-08	67.4
rs:WP_003578623	DNA topoisomerase I [Rhizobium leguminosarum].	25.82	457	261	22	107	510	75	506	3e-08	67.4
rs:WP_034631506	DNA topoisomerase I [Cellulomonas cellasea].	23.36	458	283	16	7	431	8	430	3e-08	67.4
rs:WP_022149077	DNA topoisomerase [Prevotella sp. CAG:1320].	22.71	524	320	19	7	504	6	470	3e-08	67.4
rs:XP_003104074	CRE-TOP-3 protein [Caenorhabditis remanei].	24.01	479	308	17	88	548	92	532	3e-08	67.4
rs:WP_029252025	DNA topoisomerase I [Paraoerskovia marina].	24.31	362	217	10	7	341	8	339	3e-08	67.4
rs:WP_025960898	DNA topoisomerase I [Prochlorococcus sp. scB245a_519L21].	24.61	512	291	18	107	579	91	546	3e-08	67.4
rs:WP_035491918	DNA topoisomerase I [Gammaproteobacteria bacterium MOLA455].	23.06	451	297	15	80	505	88	513	3e-08	67.4
rs:XP_008333800	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Cynoglossus semilaevis].	22.65	468	292	19	112	553	117	540	3e-08	67.4
tr:A0A024W0X4_PLAFA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW34589.1};	21.89	603	360	25	8	548	9	562	3e-08	67.0
rs:WP_017414512	hypothetical protein [Clostridium tunisiense].	23.68	549	316	25	7	512	6	494	3e-08	67.0
rs:WP_005006203	DNA topoisomerase I [Acinetobacter ursingii].	23.75	400	234	14	192	553	157	523	3e-08	67.4
tr:J6Y817_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJY35264.1}; Flags: Fragment;	32.24	152	92	3	422	563	1	151	3e-08	63.5
rs:WP_019311104	DNA topoisomerase I [Kocuria rhizophila].	23.48	528	313	17	46	505	40	544	3e-08	67.4
rs:WP_036908284	DNA topoisomerase I, partial [Prevotella ruminicola].	23.22	534	305	23	7	505	6	469	3e-08	67.0
rs:WP_022269185	DNA topoisomerase [Firmicutes bacterium CAG:424].	21.83	426	284	16	107	504	77	481	3e-08	67.0
tr:A0A0B8PQ94_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAM69255.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAM69255.1};	33.91	115	73	1	416	527	2	116	3e-08	63.5
rs:WP_021997276	DNA topoisomerase [Ruminococcus sp. CAG:724].	23.62	343	205	12	7	335	5	304	3e-08	67.0
gp:AF042825_1	DNA topoisomerase I [Pyrococcus furiosus]	27.35	234	121	10	330	546	563	764	3e-08	67.4
gp:AF042825_1	DNA topoisomerase I [Pyrococcus furiosus]	26.80	194	127	6	132	322	3	184	5e-06	60.1
rs:WP_035147206	DNA topoisomerase III, partial [Lactobacillus sakei].	28.49	179	102	5	375	550	1	156	3e-08	65.9
tr:A0A076VXS8_BACMY	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:AIK35346.1};	29.00	200	127	5	361	547	1	198	3e-08	66.6
rs:WP_011424953	DNA topoisomerase I [Rhizobium etli].	25.64	468	268	22	97	510	65	506	3e-08	67.4
tr:K1XW10_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.55	334	198	12	7	336	5	288	3e-08	67.0
rs:WP_042669874	DNA topoisomerase III, partial [Methylobacterium sp. B34].	29.36	218	118	8	5	214	3	192	3e-08	63.9
rs:WP_032056289	DNA topoisomerase I [Acinetobacter baumannii].	23.75	400	234	14	192	553	157	523	3e-08	67.0
rs:WP_010307984	DNA topoisomerase I [Saccharopolyspora spinosa].	23.21	560	323	23	7	505	2	515	3e-08	67.0
rs:XP_010597196	PREDICTED: DNA topoisomerase 3-beta-1 [Loxodonta africana].	24.44	360	208	19	216	555	227	542	3e-08	67.0
rs:XP_012337140	hypothetical protein AK88_04107 [Plasmodium fragile].	22.44	508	320	19	81	548	60	533	3e-08	67.0
rs:WP_034576267	DNA topoisomerase I [Cardinium endosymbiont of Bemisia tabaci].	23.56	556	317	23	7	539	6	476	3e-08	67.0
rs:WP_022911217	DNA topoisomerase I [Aestuariimicrobium kwangyangense].	23.16	557	337	22	3	505	2	521	4e-08	67.0
rs:WP_019160968	DNA topoisomerase I [Ruminococcus sp. JC304].	23.30	442	276	18	97	504	67	479	4e-08	67.0
rs:WP_003456151	topoisomerase I - like protein, partial [Pseudomonas aeruginosa].	23.50	349	219	11	222	553	1	318	4e-08	66.2
tr:R1YUH1_ENTFC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.82	171	104	5	279	442	43	204	4e-08	63.9
rs:WP_040177352	DNA topoisomerase I [Leuconostoc citreum].	22.71	458	292	18	7	432	6	433	4e-08	67.0
rs:WP_013670801	DNA topoisomerase I [Prevotella denticola].	23.02	530	315	18	7	504	6	474	4e-08	67.0
tr:X8A029_MYCXE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	26.76	284	172	10	86	345	63	334	4e-08	66.2
rs:WP_017192797	hypothetical protein [Italian clover phyllody phytoplasma].	24.53	428	267	15	100	504	72	466	4e-08	67.0
rs:XP_005949422	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X4 [Haplochromis burtoni].	21.96	592	358	25	7	553	6	538	4e-08	66.6
rs:WP_004611389	MULTISPECIES: DNA topoisomerase I [Clostridiales].	24.23	454	267	22	93	504	63	481	4e-08	67.0
rs:WP_032821588	topoisomerase I, partial [Oenococcus oeni].	29.35	184	117	7	279	455	39	216	4e-08	63.9
tr:A0A077TPZ5_PLACH	SubName: Full=DNA topoisomerase III, putative {ECO:0000313|EMBL:CDR16085.1};	27.86	262	147	13	282	531	343	574	4e-08	67.0
tr:K1UJ58_9ZZZZ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EKC80054.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC80054.1}; Flags: Fragment;	33.33	111	70	3	252	360	33	141	4e-08	63.5
rs:WP_036914349	DNA topoisomerase I [Prevotella sp. FD3004].	24.59	423	264	16	107	504	76	468	4e-08	67.0
tr:R0M9K0_NOSB1	SubName: Full=DNA topoisomerase 3-alpha {ECO:0000313|EMBL:EOB14659.1};	23.44	546	342	23	8	532	6	496	4e-08	67.0
rs:WP_031907700	DNA topoisomerase III, partial [Staphylococcus aureus].	30.49	164	100	5	379	531	21	181	4e-08	65.9
rs:WP_022076044	DNA topoisomerase [Firmicutes bacterium CAG:212].	23.23	439	290	17	93	504	76	494	4e-08	67.0
rs:WP_022754505	DNA topoisomerase I [Butyrivibrio fibrisolvens].	25.23	444	268	19	97	504	68	483	4e-08	66.6
rs:WP_039100590	DNA topoisomerase I [Kocuria rhizophila].	23.48	528	313	17	46	505	40	544	4e-08	67.0
rs:XP_009090585	PREDICTED: DNA topoisomerase 3-beta-1 [Serinus canaria].	22.32	587	364	23	7	553	6	540	4e-08	67.0
rs:WP_016532567	DNA topoisomerase III, partial [Klebsiella pneumoniae].	25.70	179	123	4	8	182	5	177	4e-08	63.5
rs:WP_012473240	DNA topoisomerase I [Candidatus Amoebophilus asiaticus].	23.75	539	298	24	7	504	6	472	4e-08	67.0
rs:XP_002419382	DNA topoisomerase III, putative [Candida dubliniensis CD36].	23.70	578	356	23	7	547	3	532	4e-08	66.6
tr:A0A0B1TGI7_OESDE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.41	284	173	12	278	553	228	483	4e-08	66.6
rs:XP_008573019	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Galeopterus variegatus].	22.87	481	285	22	107	553	68	496	4e-08	67.0
tr:F0L2J3_AGRSH	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.78	553	322	21	2	505	10	506	4e-08	67.0
rs:WP_021611891	DNA topoisomerase I [Actinomyces sp. oral taxon 172].	23.30	558	339	22	1	505	1	522	4e-08	67.0
rs:WP_024160721	topoisomerase I [Acinetobacter nosocomialis].	23.81	399	235	12	192	553	157	523	4e-08	67.0
rs:WP_017191419	hypothetical protein [Poinsettia branch-inducing phytoplasma].	24.71	429	266	16	100	504	72	467	4e-08	66.6
rs:WP_020327389	DNA topoisomerase III, partial [Pseudomonas syringae].	33.00	100	65	1	450	549	10	107	4e-08	63.5
rs:WP_042102551	DNA topoisomerase III, partial [Escherichia coli].	25.57	176	121	4	8	179	5	174	4e-08	63.5
rs:WP_032849228	DNA topoisomerase I, partial [Fusobacterium nucleatum].	21.88	521	331	19	7	504	11	478	4e-08	66.6
rs:XP_004989945	DNA topoisomerase [Salpingoeca rosetta].	21.70	530	343	20	48	555	60	539	4e-08	66.6
rs:WP_003512719	MULTISPECIES: DNA topoisomerase I [Agrobacterium].	22.87	551	320	21	4	505	1	495	4e-08	66.6
rs:WP_025401003	DNA topoisomerase I [Borrelia crocidurae].	23.38	603	346	26	7	561	7	541	4e-08	66.6
rs:WP_010708506	hypothetical protein, partial [Enterococcus faecalis].	26.86	175	93	4	333	491	13	168	4e-08	63.5
rs:WP_005896639	DNA topoisomerase I [Fusobacterium nucleatum].	22.58	527	320	20	7	504	14	481	4e-08	66.6
rs:WP_012557347	DNA topoisomerase I [Rhizobium leguminosarum].	26.20	458	258	22	107	510	75	506	5e-08	66.6
rs:WP_044109241	DNA topoisomerase I [Acinetobacter sp. MII].	23.69	401	237	12	192	555	157	525	5e-08	66.6
rs:WP_041694374	DNA topoisomerase I [Agrobacterium sp. H13-3].	22.87	551	320	21	4	505	1	495	5e-08	66.6
tr:A0A090KU15_STRRB	SubName: Full=DNA topoisomerase 3-beta {ECO:0000313|EMBL:CEF61010.1};	21.71	585	368	25	7	550	7	542	5e-08	66.6
rs:WP_025929859	DNA topoisomerase I [Prochlorococcus sp. scB241_528O2].	24.75	509	306	17	101	579	85	546	5e-08	66.6
rs:XP_001642518	hypothetical protein Kpol_340p7 [Vanderwaltozyma polyspora DSM 70294].	21.70	599	373	20	7	546	3	564	5e-08	66.6
rs:WP_044103448	DNA topoisomerase I [Acinetobacter pittii].	23.81	399	235	12	192	553	157	523	5e-08	66.6
rs:WP_040007276	hypothetical protein, partial [Fibrisoma limi].	23.65	406	269	13	107	500	79	455	5e-08	66.2
rs:WP_014561621	DNA topoisomerase I [Ignavibacterium album].	23.56	539	296	22	7	504	6	469	5e-08	66.6
rs:WP_021768179	DNA topoisomerase I [Leptotrichia sp. oral taxon 225].	22.47	534	310	20	7	504	6	471	5e-08	66.6
rs:WP_003587235	DNA topoisomerase I [Rhizobium leguminosarum].	26.20	458	258	22	107	510	75	506	5e-08	66.6
rs:WP_044432270	DNA topoisomerase I [Acinetobacter pittii].	23.75	400	234	14	192	553	157	523	5e-08	66.6
rs:WP_014271302	DNA topoisomerase I [Sphaerochaeta pleomorpha].	22.67	622	376	22	7	590	8	562	5e-08	66.6
rs:WP_046312892	DNA topoisomerase I [Pontibacter korlensis].	22.24	526	317	19	7	504	6	467	5e-08	66.6
tr:A0A0D6G271_FUSNP	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:CKG90094.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CKG90094.1};	22.58	527	320	20	7	504	11	478	5e-08	66.6
rs:WP_045015971	DNA topoisomerase I [Agrobacterium sp. KFB 330].	23.41	551	317	22	4	505	1	495	5e-08	66.6
tr:F6SDD7_MOUSE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.50	298	169	14	273	553	74	335	5e-08	66.2
rs:XP_008573018	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Galeopterus variegatus].	22.87	481	285	22	107	553	112	540	5e-08	66.6
rs:WP_012538567	DNA topoisomerase I [Borrelia duttonii].	23.38	603	346	26	7	561	7	541	5e-08	66.6
tr:R5I715_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.06	424	275	16	107	504	77	479	5e-08	66.2
tr:I2GTY1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.65	406	269	13	107	500	77	453	5e-08	66.2
rs:XP_005949419	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Haplochromis burtoni].	21.96	592	358	25	7	553	6	538	5e-08	66.2
rs:WP_020366332	DNA topoisomerase III, partial [Staphylococcus epidermidis].	28.98	176	98	6	447	606	24	188	5e-08	65.1
rs:WP_025479035	hypothetical protein [Enterococcus faecium].	30.30	165	99	5	285	442	2	157	5e-08	63.2
rs:WP_037224279	DNA topoisomerase I [Richelia intracellularis].	22.53	617	376	15	5	583	3	555	5e-08	66.6
rs:WP_036087905	DNA topoisomerase I [Leptotrichia hofstadii].	21.64	536	312	18	7	504	6	471	5e-08	66.6
rs:XP_008622523	DNA topoisomerase III [Plasmodium vinckei vinckei].	27.48	262	148	13	282	531	343	574	5e-08	66.2
rs:WP_021965327	DNA topoisomerase [Prevotella sp. CAG:1185].	23.00	526	314	22	7	504	6	468	5e-08	66.2
rs:WP_022809233	DNA topoisomerase I [Aminicenantes bacterium SCGC AAA252-K06].	22.16	528	326	20	7	505	6	477	6e-08	66.2
rs:WP_032885958	DNA topoisomerase I, partial [Fusobacterium nucleatum].	22.07	521	330	20	7	504	14	481	6e-08	66.2
rs:WP_005728009	topoisomerase I [Lactobacillus crispatus].	22.02	436	299	16	7	423	6	419	6e-08	66.6
rs:WP_025593271	DNA topoisomerase I [Agrobacterium tumefaciens].	23.23	551	318	22	4	505	1	495	6e-08	66.6
rs:WP_028512772	DNA topoisomerase I [Ruminococcaceae bacterium AE2021].	22.36	550	329	21	7	510	6	503	6e-08	66.2
rs:WP_039217791	DNA topoisomerase I [Clostridium novyi].	23.26	546	330	23	7	517	6	497	6e-08	66.2
rs:WP_025296797	DNA topoisomerase I [Trueperella pyogenes].	22.55	550	337	20	7	505	5	516	6e-08	66.6
rs:WP_023567308	DNA topoisomerase III, partial [Escherichia coli].	31.58	114	71	2	444	552	1	112	6e-08	63.5
rs:WP_015171261	DNA topoisomerase I [Geitlerinema sp. PCC 7407].	24.04	495	291	17	107	566	90	534	6e-08	66.6
rs:WP_021866070	DNA topoisomerase [Eubacterium sp. CAG:86].	22.84	486	320	17	47	504	21	479	6e-08	66.2
rs:WP_002574864	MULTISPECIES: DNA topoisomerase I [Lachnoclostridium].	23.18	440	294	15	93	504	63	486	6e-08	66.2
tr:J6QMH7_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJX69505.1}; Flags: Fragment;	32.24	152	92	3	422	563	1	151	6e-08	65.1
rs:XP_007196359	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Balaenoptera acutorostrata scammoni].	25.67	300	170	15	273	555	143	406	6e-08	66.2
rs:WP_016186990	DNA topoisomerase III, partial [Staphylococcus aureus].	32.48	117	74	3	447	559	4	119	6e-08	64.7
tr:U7SSI8_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.26	521	329	20	7	504	11	478	6e-08	66.2
rs:WP_010474526	DNA topoisomerase I [Acaryochloris sp. CCMEE 5410].	23.32	549	336	18	65	579	48	545	6e-08	66.2
rs:WP_039663180	DNA topoisomerase I [Trueperella pyogenes].	22.55	550	337	20	7	505	5	516	6e-08	66.2
rs:WP_034574745	DNA topoisomerase I, partial [Helicobacter sanguini].	30.26	271	153	15	260	505	15	274	6e-08	65.9
rs:WP_024963976	DNA topoisomerase I [Trueperella pyogenes].	22.55	550	337	20	7	505	5	516	6e-08	66.2
rs:WP_041224044	hypothetical protein, partial [Deferribacter desulfuricans].	22.86	538	318	22	7	504	6	486	6e-08	65.9
tr:A0A0D3FE73_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART03G04820.3};	24.10	473	299	20	97	546	76	511	6e-08	66.2
rs:WP_025415897	DNA topoisomerase I [Rhizobium leguminosarum].	25.76	458	260	22	107	510	75	506	6e-08	66.2
rs:WP_016340685	DNA topoisomerase I [Spiroplasma syrphidicola].	23.74	417	270	16	107	504	84	471	6e-08	65.9
tr:A0A0D3F547_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART02G16520.3};	23.87	511	312	19	47	504	247	733	6e-08	66.2
rs:XP_003459054	PREDICTED: DNA topoisomerase 3-beta-1 isoformX1 [Oreochromis niloticus].	21.79	592	359	25	7	553	6	538	6e-08	66.2
tr:X1KW99_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_C00401 {ECO:0000313|EMBL:GAH97920.1}; Flags: Fragment;	23.10	316	215	8	291	603	6	296	6e-08	65.5
rs:WP_021648979	DNA topoisomerase I [Bifidobacterium breve].	21.03	580	329	20	7	505	6	537	6e-08	66.2
tr:A0A0B3A985_9ARCH	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:KHO45194.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHO45194.1};	33.33	186	98	9	7	180	5	176	6e-08	63.2
rs:WP_033490460	DNA topoisomerase I [Bifidobacterium boum].	21.72	571	331	21	7	505	8	534	6e-08	66.2
rs:WP_012397547	DNA topoisomerase I [Kocuria rhizophila].	23.48	528	313	17	46	505	40	544	6e-08	66.2
tr:R9X7K6_LACPN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	27.81	187	111	6	213	389	1	173	6e-08	63.5
rs:XP_007196358	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Balaenoptera acutorostrata scammoni].	25.84	298	168	15	273	553	279	540	6e-08	66.2
tr:A0A0D2UDE4_GOSRA	SubName: Full=Gossypium raimondii chromosome 10, whole genome shotgun sequence {ECO:0000313|EMBL:KJB66051.1}; Flags: Fragment;	26.77	310	185	12	47	335	291	579	6e-08	65.9
rs:WP_024160892	MULTISPECIES: topoisomerase I [Acinetobacter].	23.69	401	237	12	192	555	157	525	6e-08	66.2
rs:WP_034727019	DNA topoisomerase I [Chryseobacterium sp. JM1].	22.03	522	321	21	7	505	6	464	6e-08	66.2
rs:WP_027341883	DNA topoisomerase I [Hamadaea tsunoensis].	21.98	546	338	17	7	505	10	514	6e-08	66.2
tr:A0A0D3F546_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART02G16520.2};	23.87	511	312	19	47	504	247	733	6e-08	66.2
rs:WP_021898243	DNA topoisomerase [Faecalibacterium sp. CAG:1138].	23.11	541	327	23	8	506	6	499	6e-08	66.2
rs:WP_042811193	DNA topoisomerase III, partial [Xanthomonas citri].	32.63	95	62	1	458	552	5	97	6e-08	63.5
rs:WP_032884070	DNA topoisomerase I [Fusobacterium nucleatum].	22.26	521	329	20	7	504	14	481	7e-08	66.2
rs:XP_006522060	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Mus musculus].	25.68	296	171	15	273	553	279	540	7e-08	66.2
rs:WP_040958459	DNA topoisomerase I [Sinorhizobium fredii].	23.29	554	314	24	4	505	1	495	7e-08	66.2
rs:WP_007339188	DNA topoisomerase I [Rhodopirellula baltica].	23.53	561	344	21	2	513	29	553	7e-08	66.2
rs:WP_007334156	DNA topoisomerase I [Rhodopirellula baltica].	23.53	561	344	21	2	513	29	553	7e-08	66.2
rs:WP_025941380	DNA topoisomerase I [Prochlorococcus sp. scB245a_518O7].	24.65	507	297	19	107	579	91	546	7e-08	66.2
rs:WP_028659797	DNA topoisomerase I [Nocardioides insulae].	22.12	642	385	28	7	593	6	587	7e-08	66.2
tr:A0A0B7NMC0_9FUNG	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.07	598	393	23	48	607	50	606	7e-08	66.2
tr:E6YR65_9RHIZ	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.94	453	272	20	97	505	65	493	7e-08	66.2
rs:WP_017144898	DNA topoisomerase I [Fusobacterium nucleatum].	22.07	521	330	20	7	504	14	481	7e-08	66.2
rs:XP_007451079	PREDICTED: DNA topoisomerase 3-beta-1 [Lipotes vexillifer].	25.50	298	169	15	273	553	279	540	7e-08	66.2
rs:WP_025973185	DNA topoisomerase I [Prochlorococcus sp. scB241_528P18].	24.85	507	296	19	107	579	91	546	7e-08	66.2
rs:WP_014696639	DNA topoisomerase I [Borrelia crocidurae].	23.38	603	346	26	7	561	7	541	7e-08	66.2
rs:XP_007130667	PREDICTED: DNA topoisomerase 3-beta-1 [Physeter catodon].	25.84	298	168	15	273	553	279	540	7e-08	66.2
rs:WP_031509212	DNA topoisomerase I [Streptomyces megasporus].	24.03	462	277	17	97	505	90	530	7e-08	66.2
tr:A0A023CUK7_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.44	338	201	13	198	504	6	323	7e-08	65.9
rs:WP_004066811	DNA topoisomerase I [Thermococcus litoralis].	29.45	163	90	4	382	539	54	196	7e-08	65.5
tr:H1HCE5_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.07	521	330	20	7	504	11	478	7e-08	65.9
rs:WP_036901249	DNA topoisomerase I [Prochlorococcus sp. MIT 0601].	23.03	595	367	18	7	568	6	542	7e-08	66.2
tr:C0AQN3_9ENTR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEG87686.1};	33.02	106	64	2	448	548	29	132	7e-08	63.2
rs:XP_011104558	top3p [Saccharomyces arboricola H-6].	23.02	643	365	29	7	569	3	595	7e-08	65.9
rs:WP_027598369	MULTISPECIES: DNA topoisomerase I [Pseudomonas].	22.64	424	289	13	99	505	102	503	7e-08	66.2
tr:A5ZUI2_9FIRM	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EDM86762.1};	25.82	213	128	6	371	554	20	231	7e-08	64.7
rs:WP_040101054	DNA topoisomerase III, partial [Escherichia coli].	27.22	180	122	5	7	184	4	176	7e-08	62.8
rs:WP_038055559	hypothetical protein [Thermodesulfobacterium hydrogeniphilum].	24.21	537	327	23	83	590	50	535	7e-08	65.9
rs:WP_033160278	DNA topoisomerase I [Mycoplasma alvi].	21.50	535	354	15	91	593	67	567	7e-08	65.9
rs:WP_027205421	DNA topoisomerase I [Butyrivibrio fibrisolvens].	25.23	444	268	19	97	504	68	483	7e-08	65.9
rs:WP_024060732	DNA topoisomerase, partial [Veillonella dispar].	35.64	101	62	1	462	559	67	167	7e-08	63.2
rs:WP_003573867	DNA topoisomerase I [Rhizobium leguminosarum].	25.76	458	260	22	107	510	75	506	7e-08	66.2
rs:WP_032878736	DNA topoisomerase I [Fusobacterium nucleatum].	23.14	523	322	23	7	504	11	478	8e-08	65.9
tr:J6XCP6_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJX43731.1}; Flags: Fragment;	32.24	152	92	3	422	563	1	151	8e-08	64.3
rs:WP_011862458	DNA topoisomerase I [Prochlorococcus marinus].	24.76	513	301	19	101	579	85	546	8e-08	65.9
rs:WP_021655081	DNA topoisomerase I [Clostridiales bacterium oral taxon 876].	24.89	450	272	19	107	517	77	499	8e-08	65.9
rs:WP_032825813	topoisomerase I, partial [Oenococcus oeni].	28.16	206	131	8	313	508	3	201	8e-08	63.2
rs:WP_006949726	DNA topoisomerase I [Prevotella marshii].	23.46	520	322	19	7	505	6	470	8e-08	65.9
rs:WP_038688242	DNA topoisomerase I [Rhizobium etli].	25.43	464	274	22	97	510	65	506	8e-08	65.9
rs:WP_031216855	DNA topoisomerase I [Arthrobacter sp. AK-YN10].	21.77	496	326	19	4	472	2	462	8e-08	65.9
rs:WP_005028476	DNA topoisomerase I [Acinetobacter bereziniae].	23.81	399	235	12	192	553	157	523	8e-08	65.9
rs:WP_007599335	DNA topoisomerase I [Rhizobium sp. PDO1-076].	24.00	550	316	25	4	505	1	496	8e-08	65.9
rs:WP_025926091	DNA topoisomerase I [Prochlorococcus sp. scB241_528J8].	25.05	507	295	18	107	579	91	546	8e-08	65.9
rs:WP_028700909	DNA topoisomerase I [Propionibacterium acidipropionici].	23.48	477	284	20	86	505	72	524	8e-08	66.2
rs:XP_006993093	PREDICTED: DNA topoisomerase 3-beta-1 [Peromyscus maniculatus bairdii].	25.68	296	167	15	275	553	281	540	8e-08	65.9
rs:WP_013272516	DNA topoisomerase I [[Clostridium] saccharolyticum].	23.15	445	285	15	93	504	63	483	8e-08	65.9
tr:K1TJK5_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EKC59411.1}; Flags: Fragment;	27.44	328	195	15	198	498	17	328	8e-08	65.1
tr:A0A0C9MP41_9FUNG	SubName: Full=DNA, scaffold: scf_mam1_v10081, strain NBRC 6742, whole genome shotgun sequence {ECO:0000313|EMBL:GAN05052.1};	21.35	576	372	20	13	555	38	565	8e-08	65.5
rs:WP_024905748	hypothetical protein [Burkholderia andropogonis].	28.26	184	103	6	405	561	3	184	8e-08	64.7
tr:X1D987_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S13632 {ECO:0000313|EMBL:GAG92961.1}; Flags: Fragment;	30.25	238	144	10	99	326	45	270	8e-08	63.9
rs:WP_040999438	DNA topoisomerase I [Chryseobacterium oranimense].	21.56	524	319	22	7	504	6	463	8e-08	65.9
tr:B3V6G7_9ARCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.91	368	240	15	7	358	20	363	8e-08	65.1
rs:WP_012246114	DNA topoisomerase I [Renibacterium salmoninarum].	23.23	564	314	23	7	505	17	526	8e-08	65.9
rs:WP_022858104	DNA topoisomerase I [Bifidobacterium pseudolongum].	21.57	561	326	22	7	505	8	516	8e-08	65.9
rs:XP_005489017	PREDICTED: DNA topoisomerase 3-beta-1 [Zonotrichia albicollis].	24.50	351	215	15	216	553	261	574	8e-08	65.9
tr:Z9JPX2_9MICO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.91	550	335	20	7	505	9	520	8e-08	65.9
rs:XP_005464354	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Oreochromis niloticus].	21.89	475	301	18	104	553	100	529	8e-08	65.9
tr:X8IE43_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.07	521	330	20	7	504	11	478	8e-08	65.9
rs:WP_027413100	DNA topoisomerase I [Aquimarina muelleri].	25.30	423	263	15	103	504	73	463	8e-08	65.9
rs:WP_017706951	hypothetical protein, partial [Pseudomonas syringae].	38.26	115	60	3	443	548	1	113	8e-08	63.2
tr:X5JYV5_9NOST	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.96	527	319	15	95	583	49	526	8e-08	65.9
tr:J7CFA4_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJY32177.1}; Flags: Fragment;	33.99	153	88	5	422	563	1	151	8e-08	64.3
rs:XP_003459055	PREDICTED: DNA topoisomerase 3-beta-1 isoformX2 [Oreochromis niloticus].	23.51	285	170	12	283	553	290	540	8e-08	65.9
rs:WP_034018030	DNA topoisomerase III, partial [Pseudomonas aeruginosa].	25.78	225	152	6	8	230	5	216	9e-08	62.8
rs:WP_016734024	DNA topoisomerase I [Rhizobium phaseoli].	25.77	454	265	22	107	510	75	506	9e-08	65.9
tr:G2TJM1_BACCO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.34	371	226	14	163	504	3	351	9e-08	65.5
rs:WP_023244078	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	25.42	421	239	17	7	398	6	380	9e-08	65.1
rs:WP_034740368	DNA topoisomerase I [Chryseobacterium vrystaatense].	22.03	522	321	21	7	505	6	464	9e-08	65.9
rs:WP_028899889	DNA topoisomerase I [Prevotella sp. HJM029].	24.25	433	260	13	7	430	6	379	9e-08	65.9
rs:WP_012707655	DNA topoisomerase I [Sinorhizobium fredii].	23.27	550	319	24	4	505	1	495	9e-08	65.9
rs:WP_021743820	DNA topoisomerase I [Leptotrichia sp. oral taxon 879].	21.80	532	316	18	7	504	6	471	9e-08	65.9
rs:XP_002199057	PREDICTED: DNA topoisomerase 3-beta-1 [Taeniopygia guttata].	24.08	353	218	15	216	555	367	682	9e-08	65.9
rs:WP_018814389	DNA topoisomerase I [Salinispora pacifica].	24.23	454	264	20	107	505	96	524	9e-08	65.9
rs:WP_035440335	DNA topoisomerase I, partial [Asaia sp. SF2.1].	25.19	270	159	11	276	510	5	266	9e-08	65.5
rs:WP_008691655	DNA topoisomerase I [Fusobacterium nucleatum].	22.07	521	330	20	7	504	14	481	9e-08	65.9
rs:WP_039619142	DNA topoisomerase I [Rhizobium etli].	25.43	464	274	22	97	510	65	506	9e-08	65.9
rs:WP_010732770	DNA topoisomerase 1 [Enterococcus faecium].	23.57	526	323	18	7	504	7	481	9e-08	65.5
tr:E2XNF4_PSEFL	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.16	380	243	13	147	505	46	397	9e-08	65.9
rs:WP_032837410	DNA topoisomerase I [Fusobacterium sp. CM1].	22.07	521	330	20	7	504	14	481	9e-08	65.9
rs:XP_005949421	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X3 [Haplochromis burtoni].	21.89	475	301	17	104	553	56	485	9e-08	65.5
rs:WP_021915113	GTP-sensing transcriptional pleiotropic repressor CodY [Firmicutes bacterium CAG:24].	22.07	444	288	17	93	504	63	480	9e-08	65.5
tr:R9RD65_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.26	521	329	20	7	504	11	478	9e-08	65.9
rs:XP_012433502	PREDICTED: DNA topoisomerase 3-beta-1 [Taeniopygia guttata].	24.08	353	218	15	216	555	296	611	9e-08	65.9
rs:WP_002847138	DNA topoisomerase I [Ruminococcus albus].	24.76	420	257	16	107	495	76	467	9e-08	65.5
rs:WP_010891344	hypothetical protein, partial [Streptococcus agalactiae].	29.61	152	101	3	398	544	1	151	9e-08	64.3
rs:WP_012560269	DNA topoisomerase I [Ureaplasma urealyticum].	23.64	423	274	13	107	500	81	483	9e-08	65.5
rs:WP_009779100	DNA topoisomerase I [Leeuwenhoekiella blandensis].	23.75	539	311	24	7	512	6	477	9e-08	65.9
rs:WP_026819570	DNA topoisomerase I [Arthrobacter castelli].	22.20	554	336	20	7	505	16	529	9e-08	65.9
rs:WP_019530187	topoisomerase I [Dasania marina].	22.25	454	312	14	69	505	78	507	9e-08	65.9
rs:WP_034737625	DNA topoisomerase I [Chryseobacterium indologenes].	22.05	526	314	23	7	504	6	463	1e-07	65.9
rs:WP_038373706	DNA topoisomerase I [Brachybacterium phenoliresistens].	22.91	550	335	20	7	505	8	519	1e-07	65.9
rs:WP_026544435	DNA topoisomerase I [Arthrobacter sp. 35/47].	23.73	573	307	25	7	505	15	531	1e-07	65.9
tr:Q14PN0_SPICI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.18	523	328	18	5	504	4	470	1e-07	65.5
tr:U2DY69_9BACE	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ERI84806.1};	30.17	179	115	7	376	550	36	208	1e-07	64.7
rs:WP_005729394	topoisomerase I [Lactobacillus crispatus].	23.39	342	230	12	7	335	6	328	1e-07	65.9
rs:WP_037138139	DNA topoisomerase I [Rhizobium leguminosarum].	25.77	454	265	22	107	510	75	506	1e-07	65.9
tr:T1JEW7_STRMM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.75	422	265	16	107	498	111	501	1e-07	65.9
tr:A0A072C6M9_RHILP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	25.77	454	265	22	107	510	71	502	1e-07	65.9
rs:WP_035342062	DNA topoisomerase III, partial [Dickeya sp. DW 0440].	25.37	205	136	6	8	206	5	198	1e-07	62.8
rs:WP_038821518	hypothetical protein [Pseudomonas syringae].	44.83	87	46	1	462	548	19	103	1e-07	62.8
rs:WP_023041398	DNA topoisomerase I [Fusobacterium nucleatum].	22.65	521	327	21	7	504	11	478	1e-07	65.5
rs:WP_005902939	DNA topoisomerase I [Fusobacterium nucleatum].	22.65	521	327	21	7	504	14	481	1e-07	65.5
rs:WP_041461236	DNA topoisomerase I [Fusobacterium nucleatum].	22.26	521	329	20	7	504	14	481	1e-07	65.5
rs:WP_027374086	DNA topoisomerase I [Chryseobacterium sp. UNC8MFCol].	22.05	526	314	23	7	504	6	463	1e-07	65.5
rs:WP_012483459	DNA topoisomerase I [Rhizobium etli].	25.77	454	265	22	107	510	75	506	1e-07	65.5
tr:A0A0D2V9F9_GOSRA	SubName: Full=Gossypium raimondii chromosome 10, whole genome shotgun sequence {ECO:0000313|EMBL:KJB66050.1}; Flags: Fragment;	26.77	310	185	12	47	335	344	632	1e-07	65.5
rs:WP_044452491	DNA topoisomerase I, partial [Mastigocladus laminosus].	29.82	228	137	9	289	504	3	219	1e-07	65.1
rs:WP_009369974	DNA topoisomerase I [Megasphaera genomosp. type_1].	22.93	532	324	19	7	504	56	535	1e-07	65.5
tr:A0A0D2GQU9_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.90	630	389	24	7	602	6	566	1e-07	65.5
tr:W8FAX8_RHIRD	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.78	448	261	19	107	505	34	454	1e-07	65.5
tr:U7TA88_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.26	521	329	20	7	504	11	478	1e-07	65.5
tr:G7JBC7_MEDTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.76	525	322	28	7	498	8	492	1e-07	65.5
gp:CP005079_107	DNA topoisomerase I [Erysipelothrix rhusiopathiae SY1027]	28.61	367	224	14	36	390	9	349	1e-07	64.7
rs:XP_975504	PREDICTED: DNA topoisomerase 3-beta-1 [Tribolium castaneum].	22.29	471	300	18	107	553	111	539	1e-07	65.5
tr:A0A0D9WP91_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:LPERR06G09500.1};	24.62	455	280	16	97	505	370	807	1e-07	65.5
rs:WP_004905365	DNA topoisomerase I [Leuconostoc citreum].	22.71	458	292	18	7	432	6	433	1e-07	65.5
rs:WP_037169524	DNA topoisomerase I [Rhizobium sp. CF258].	24.32	555	307	26	4	505	1	495	1e-07	65.5
rs:WP_021596265	DNA topoisomerase I [Actinomadura madurae].	22.10	552	334	19	7	505	1	509	1e-07	65.5
rs:WP_029125058	DNA topoisomerase I [Salinispora pacifica].	24.23	454	264	20	107	505	96	524	1e-07	65.5
rs:WP_018743856	DNA topoisomerase I [Salinispora pacifica].	24.23	454	264	20	107	505	96	524	1e-07	65.5
rs:WP_032515553	DNA topoisomerase I [Prochlorococcus marinus].	24.90	510	304	19	101	579	85	546	1e-07	65.5
rs:WP_023074624	dna topoisomerase i [Leptolyngbya sp. Heron Island J].	23.86	503	294	16	101	566	84	534	1e-07	65.5
rs:WP_022500236	DNA topoisomerase [Firmicutes bacterium CAG:95].	21.82	440	295	16	93	504	63	481	1e-07	65.5
rs:WP_032839643	DNA topoisomerase I [Fusobacterium nucleatum].	22.26	521	329	20	7	504	14	481	1e-07	65.5
rs:WP_046530015	DNA topoisomerase I [Cellulomonas sp. FA1].	22.62	557	335	21	7	505	8	526	1e-07	65.5
rs:WP_032888841	DNA topoisomerase I [Fusobacterium nucleatum].	22.58	527	320	20	7	504	14	481	1e-07	65.5
rs:XP_006213369	PREDICTED: DNA topoisomerase 3-beta-1 [Vicugna pacos].	25.33	300	171	15	273	555	279	542	1e-07	65.5
rs:WP_032836200	DNA topoisomerase I [Fusobacterium sp. OBRC1].	22.39	527	321	21	7	504	14	481	1e-07	65.5
tr:D3PEJ4_DEFDS	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:BAI81636.1};	22.86	538	318	22	7	504	6	486	1e-07	65.5
rs:WP_020002986	MULTISPECIES: DNA topoisomerase I [Mycoplasma].	20.52	536	354	16	7	518	5	492	1e-07	65.1
tr:A0A098LAU1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.26	539	330	19	89	581	26	521	1e-07	65.5
tr:X8HMV1_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.39	527	321	21	7	504	11	478	1e-07	65.5
tr:A0A0C5PKD8_LACSK	SubName: Full=Lactobacillus sakei strain KCA311 plasmid pKCA54, complete sequence {ECO:0000313|EMBL:AJQ16950.1};	27.89	190	120	8	282	462	18	199	1e-07	62.4
rs:WP_004668461	DNA topoisomerase I [Rhizobium etli].	25.77	454	265	22	107	510	75	506	1e-07	65.5
rs:WP_004906674	DNA topoisomerase I [Leuconostoc citreum].	22.71	458	292	18	7	432	6	433	1e-07	65.5
rs:WP_027216148	DNA topoisomerase I [Butyrivibrio fibrisolvens].	25.00	444	269	19	97	504	68	483	1e-07	65.5
tr:A0A099P2L0_ISSOR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.22	522	335	17	48	545	6	480	1e-07	65.1
tr:X0SJG8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H1_L03787 {ECO:0000313|EMBL:GAF76007.1}; Flags: Fragment;	26.04	265	168	10	254	498	173	429	1e-07	64.7
tr:U7TQJ4_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.58	527	320	20	7	504	11	478	1e-07	65.5
rs:WP_013908188	DNA topoisomerase I [Thermodesulfatator indicus].	24.32	440	280	14	107	516	77	493	1e-07	65.5
rs:XP_005421521	PREDICTED: DNA topoisomerase 3-beta-1 [Geospiza fortis].	24.22	351	216	15	216	553	202	515	1e-07	65.5
rs:WP_036898276	DNA topoisomerase I [Prevotella sp. S7 MS 2].	24.33	526	308	23	7	504	6	469	1e-07	65.5
rs:WP_032517561	DNA topoisomerase I [Prochlorococcus marinus].	24.71	510	305	19	101	579	85	546	1e-07	65.5
tr:H0ZEB7_TAEGU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.22	351	216	15	216	553	204	517	1e-07	65.5
rs:WP_040190559	DNA topoisomerase I [Leuconostoc citreum].	22.71	458	292	18	7	432	6	433	1e-07	65.1
rs:XP_009622052	PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Nicotiana tomentosiformis].	21.11	559	367	19	10	534	18	536	1e-07	65.5
rs:WP_035965140	DNA topoisomerase I [Kocuria marina].	23.66	524	316	16	46	505	40	543	1e-07	65.5
rs:WP_022756508	DNA topoisomerase I [Butyrivibrio fibrisolvens].	25.00	444	269	19	97	504	68	483	1e-07	65.1
rs:WP_027205784	DNA topoisomerase I [Butyrivibrio fibrisolvens].	25.00	444	269	19	97	504	68	483	1e-07	65.1
rs:WP_033641536	DNA topoisomerase, partial [Enterococcus faecium].	26.49	151	105	2	101	248	3	150	1e-07	62.0
tr:A0A090LMM2_STRRB	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.82	482	290	21	106	555	110	541	1e-07	65.5
tr:L8HVJ0_9CETA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.84	298	168	15	273	553	279	540	1e-07	65.5
rs:WP_009212596	DNA topoisomerase I [Actinomyces sp. oral taxon 180].	23.13	562	335	18	1	505	1	522	1e-07	65.5
rs:WP_005723191	topoisomerase I [Lactobacillus crispatus].	23.10	342	231	12	7	335	6	328	1e-07	65.5
rs:WP_037212691	DNA topoisomerase I [Rhizobium sp. YR295].	24.32	555	307	26	4	505	1	495	1e-07	65.5
rs:XP_009622053	PREDICTED: DNA topoisomerase 3-alpha isoform X5 [Nicotiana tomentosiformis].	21.11	559	367	19	10	534	18	536	1e-07	65.1
rs:WP_037096283	DNA topoisomerase I [Rhizobium alamii].	25.59	469	268	23	97	510	65	507	1e-07	65.5
tr:U7SXU1_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.46	521	328	21	7	504	11	478	1e-07	65.5
sp:TOP3B_MOUSE	RecName: Full=DNA topoisomerase 3-beta-1; EC=5.99.1.2; AltName: Full=DNA topoisomerase III beta-1;	25.84	298	168	15	273	553	279	540	1e-07	65.5
tr:Q6XZ01_SPIKU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.14	524	327	19	5	504	4	470	1e-07	65.1
rs:XP_005949420	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X2 [Haplochromis burtoni].	21.89	475	301	17	104	553	100	529	1e-07	65.1
rs:XP_010850479	PREDICTED: DNA topoisomerase 3-beta-1 [Bison bison bison].	25.84	298	168	15	273	553	279	540	1e-07	65.5
rs:WP_027334725	DNA topoisomerase I [Mycoplasma felifaucium].	22.77	426	270	14	105	504	76	468	1e-07	65.1
tr:M6CI84_LEPME	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EMJ85945.1};	24.03	412	252	16	148	522	17	404	1e-07	65.1
rs:XP_005745890	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Pundamilia nyererei].	22.18	595	353	27	7	553	6	538	1e-07	65.1
tr:X7RZ04_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.58	527	320	20	7	504	11	478	1e-07	65.1
rs:WP_022278767	hypothetical protein [Dorea formicigenerans CAG:28].	29.01	131	78	2	376	491	33	163	1e-07	62.0
rs:WP_008700964	DNA topoisomerase I [Fusobacterium nucleatum].	22.26	521	329	20	7	504	14	481	1e-07	65.1
rs:XP_005670970	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Sus scrofa].	25.84	298	168	15	275	555	145	406	1e-07	65.1
rs:WP_023253166	DNA topoisomerase III, partial [Salmonella enterica].	39.02	82	48	2	326	406	6	86	1e-07	60.5
rs:XP_010985627	PREDICTED: DNA topoisomerase 3-beta-1, partial [Camelus dromedarius].	25.33	300	171	15	273	555	279	542	1e-07	65.1
tr:A0A090RH67_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL14546.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL14546.1};	29.88	164	105	5	7	167	15	171	1e-07	62.0
rs:WP_005916915	DNA topoisomerase I [Fusobacterium hwasookii].	23.08	520	328	20	7	505	11	479	1e-07	65.1
rs:WP_023034502	DNA topoisomerase I [Propionibacterium sp. KPL1844].	22.81	469	287	18	89	505	75	520	1e-07	65.1
rs:NP_001193635	DNA topoisomerase 3-beta-1 [Bos taurus].	25.84	298	168	15	273	553	279	540	1e-07	65.1
tr:K2GJ82_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKE30519.1};	26.18	191	131	4	417	602	4	189	1e-07	63.5
rs:WP_032865663	DNA topoisomerase I, partial [Pseudomonas fluorescens].	22.63	380	245	13	147	505	10	361	1e-07	65.1
rs:WP_022171308	GTP-sensing transcriptional pleiotropic repressor CodY [Blautia sp. CAG:52].	23.54	446	280	18	93	504	63	481	1e-07	65.1
rs:WP_002351481	hypothetical protein, partial [Enterococcus faecium].	32.00	125	75	3	376	491	29	152	1e-07	61.6
rs:XP_010953763	PREDICTED: DNA topoisomerase 3-beta-1 [Camelus bactrianus].	25.50	298	169	15	273	553	279	540	1e-07	65.1
rs:WP_032891759	DNA topoisomerase I [Fusobacterium nucleatum].	22.58	527	320	20	7	504	14	481	1e-07	65.1
rs:WP_044726088	DNA topoisomerase I, partial [Escherichia coli].	24.78	448	263	19	7	424	6	409	1e-07	64.3
rs:WP_041849652	DNA topoisomerase I [Bartonella bacilliformis].	23.58	547	313	25	7	505	4	493	1e-07	65.1
rs:WP_022069750	DNA topoisomerase [Fusobacterium sp. CAG:649].	22.07	521	330	20	7	504	11	478	1e-07	65.1
tr:K2NNY8_TRYCR	SubName: Full=DNA topoisomerase IA, putative {ECO:0000313|EMBL:EKF30567.1};	24.26	404	236	15	97	449	118	502	1e-07	65.1
rs:XP_003359220	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Sus scrofa].	26.01	296	166	15	275	553	281	540	2e-07	65.1
rs:WP_034692419	DNA topoisomerase I [Chryseobacterium sp. CF365].	22.10	525	315	22	7	504	6	463	2e-07	65.1
tr:G1WVF4_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGX69669.1};	29.01	131	78	2	376	491	33	163	2e-07	61.6
rs:WP_022448738	DNA topoisomerase [Roseburia sp. CAG:303].	23.85	436	283	17	97	504	67	481	2e-07	65.1
tr:K1SSS7_9ZZZZ	SubName: Full=Protein containing DNA topoisomerase, type IA, central domain protein {ECO:0000313|EMBL:EKC60568.1}; EC=5.99.1.3 {ECO:0000313|EMBL:EKC60568.1}; Flags: Fragment;	29.37	143	91	3	402	539	11	148	2e-07	62.0
tr:D1NGU7_HAEIF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	36.17	94	57	3	255	346	57	149	2e-07	61.6
rs:WP_004137143	DNA topoisomerase I [Gardnerella vaginalis].	22.72	559	326	24	7	505	8	520	2e-07	65.1
rs:WP_025939426	DNA topoisomerase I [Prochlorococcus sp. scB245a_520B18].	24.76	513	301	19	101	579	85	546	2e-07	65.1
rs:WP_043327234	DNA topoisomerase I [Micromonospora sp. M42].	22.58	558	329	23	7	505	11	524	2e-07	65.1
rs:WP_004026228	DNA topoisomerase I [Ureaplasma urealyticum].	23.64	423	274	13	107	500	81	483	2e-07	64.7
rs:WP_011283668	DNA topoisomerase I [Mycoplasma synoviae].	20.52	536	354	16	7	518	5	492	2e-07	64.7
rs:XP_002153907	PREDICTED: DNA topoisomerase 3-beta-1-like [Hydra vulgaris].	21.42	579	378	19	4	553	3	533	2e-07	65.1
rs:WP_034709441	DNA topoisomerase I [Chryseobacterium soli].	21.84	522	320	22	7	504	6	463	2e-07	65.1
rs:XP_006814887	PREDICTED: DNA topoisomerase 3-beta-1 [Saccoglossus kowalevskii].	21.90	420	272	15	107	498	111	502	2e-07	65.1
rs:WP_011679272	DNA topoisomerase I [Leuconostoc mesenteroides].	21.23	471	283	14	7	432	6	433	2e-07	64.7
tr:A0A0E0PWE4_ORYRU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORUFI06G11430.1};	24.06	478	277	17	107	510	376	841	2e-07	65.1
rs:XP_005907409	PREDICTED: DNA topoisomerase 3-beta-1 [Bos mutus].	25.67	300	170	15	273	555	279	542	2e-07	65.1
tr:W7VGT4_9ACTO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.58	558	329	23	7	505	52	565	2e-07	65.1
tr:D2I7M2_AILME	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.33	300	171	15	273	555	256	519	2e-07	64.7
rs:XP_001609564	DNA topoisomerase [Babesia bovis T2Bo].	24.03	491	294	19	104	555	125	575	2e-07	64.7
tr:G0UED6_9LACT	SubName: Full=Topoisomerase IA {ECO:0000313|EMBL:CCC56083.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CCC56083.1};	22.37	447	297	17	7	427	5	427	2e-07	64.7
rs:WP_022354894	DNA topoisomerase [Bacteroides sp. CAG:875].	23.21	517	320	19	7	504	6	464	2e-07	64.7
rs:WP_027218029	DNA topoisomerase I [Butyrivibrio fibrisolvens].	25.00	444	269	19	97	504	68	483	2e-07	64.7
rs:XP_008695765	PREDICTED: DNA topoisomerase 3-beta-1 [Ursus maritimus].	25.50	298	169	15	273	553	279	540	2e-07	64.7
rs:WP_009056800	DNA topoisomerase I [Atopobium sp. ICM58].	23.30	558	339	22	1	505	1	522	2e-07	64.7
rs:XP_012013093	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Ovis aries musimon].	26.13	287	163	16	284	555	290	542	2e-07	64.7
tr:D6BDD4_FUSNU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.07	521	330	20	7	504	14	481	2e-07	64.7
rs:XP_001785468	predicted protein [Physcomitrella patens].	22.05	594	362	26	1	553	1	534	2e-07	64.7
rs:WP_005225215	MULTISPECIES: topoisomerase [Enterococcus].	31.62	117	76	2	108	223	1	114	2e-07	60.8
rs:WP_035295700	DNA topoisomerase I [Clostridium sp. ASF356].	23.98	442	278	18	93	504	72	485	2e-07	64.7
tr:G0UCD3_TRYVY	SubName: Full=Putative DNA topoisomerase III {ECO:0000313|EMBL:CCC53485.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CCC53485.1};	26.00	250	157	8	308	553	244	469	2e-07	64.7
rs:WP_021210529	DNA topoisomerase I [Leuconostoc mesenteroides].	21.23	471	283	14	7	432	6	433	2e-07	64.7
rs:XP_006140260	PREDICTED: DNA topoisomerase 3-beta-1 [Tupaia chinensis].	26.01	296	166	15	275	553	281	540	2e-07	64.7
tr:A0A0C7C736_9FUNG	SubName: Full=RMATCC62417_13354 protein {ECO:0000313|EMBL:CEG78807.1};	26.75	228	151	9	277	498	123	340	2e-07	64.7
rs:WP_029945924	DNA topoisomerase I, partial [Aminicenantes bacterium SCGC AAA252-P19].	23.60	394	254	14	136	505	22	392	2e-07	64.3
tr:K1S8S4_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC51824.1}; Flags: Fragment;	38.89	72	43	1	461	532	6	76	2e-07	60.1
rs:XP_011216356	PREDICTED: DNA topoisomerase 3-beta-1 [Ailuropoda melanoleuca].	25.50	298	169	15	273	553	279	540	2e-07	64.7
rs:WP_025880938	DNA topoisomerase I [Prevotella baroniae].	24.66	438	252	15	7	430	6	379	2e-07	64.7
rs:XP_008788964	PREDICTED: uncharacterized protein LOC103706593 [Phoenix dactylifera].	23.59	513	312	20	47	505	314	800	2e-07	64.7
rs:WP_028527339	DNA topoisomerase I [Ruminococcus gauvreauii].	22.33	533	323	23	7	504	6	482	2e-07	64.7
rs:WP_033659604	DNA topoisomerase, partial [Enterococcus faecium].	31.79	151	92	3	423	563	1	150	2e-07	63.2
tr:A0A0E0NET6_ORYRU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORUFI02G17070.2};	23.87	511	312	18	47	504	257	743	2e-07	64.7
tr:N1ZMY9_9CLOT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.98	442	278	18	93	504	78	491	2e-07	64.7
rs:WP_023252897	DNA topoisomerase III, partial [Salmonella enterica].	30.51	118	75	2	440	552	23	138	2e-07	62.0
rs:WP_012576623	DNA topoisomerase I [Bifidobacterium longum].	21.88	585	325	24	7	505	6	544	2e-07	64.7
tr:Q5XLH9_LISMN	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	28.05	221	131	7	136	344	14	218	2e-07	62.4
rs:WP_004901438	DNA topoisomerase I [Leuconostoc citreum].	22.71	458	292	18	7	432	6	433	2e-07	64.7
rs:WP_044518456	hypothetical protein, partial [Hymenobacter sp. DG25B].	26.44	348	219	10	91	430	61	379	2e-07	64.3
rs:WP_029599011	DNA topoisomerase I [Fusobacterium nucleatum].	22.07	521	330	20	7	504	14	481	2e-07	64.7
tr:U1PCP6_9EURY	SubName: Full=Topoisomerase IA {ECO:0000313|EMBL:ERG89851.1}; Flags: Fragment;	27.54	167	99	4	376	539	37	184	2e-07	64.3
rs:XP_003881018	DNA topoisomerase, related [Neospora caninum Liverpool].	23.62	271	179	9	279	544	332	579	2e-07	64.7
tr:W4M454_9DELT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	21.56	320	206	11	7	322	6	284	2e-07	63.2
tr:A0A090T6U4_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	33.96	106	66	3	309	412	1	104	2e-07	60.5
tr:A0A0D3F545_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART02G16520.1};	23.45	516	313	18	47	504	247	738	2e-07	64.7
rs:WP_036858196	hypothetical protein, partial [Prevotella amnii].	30.30	132	79	5	290	420	73	192	2e-07	61.6
tr:R1YY17_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOF91245.1}; Flags: Fragment;	30.00	150	99	3	400	544	2	150	2e-07	62.8
tr:A0A072V0B5_MEDTR	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	24.26	408	268	19	107	498	50	432	2e-07	64.7
rs:XP_003033227	hypothetical protein SCHCODRAFT_54192 [Schizophyllum commune H4-8].	23.24	611	378	24	7	573	3	566	2e-07	64.3
tr:F7JP29_9FIRM	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGN36663.1};	24.54	216	143	4	81	291	5	205	2e-07	61.6
rs:WP_027853634	DNA topoisomerase I [Marinobacterium litorale].	21.50	642	397	25	5	599	4	585	2e-07	64.7
tr:W7C9U0_BROTH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.23	326	212	13	204	504	4	319	2e-07	64.3
rs:WP_031613111	DNA topoisomerase III, partial [Salmonella enterica].	25.14	175	121	4	8	178	5	173	2e-07	61.2
rs:XP_004386256	PREDICTED: DNA topoisomerase 3-beta-1 [Trichechus manatus latirostris].	24.72	360	207	19	216	555	227	542	2e-07	64.7
rs:XP_011683116	PREDICTED: DNA topoisomerase 3-beta-1 [Strongylocentrotus purpuratus].	22.33	421	268	17	107	498	15	405	2e-07	64.3
tr:G1QHD0_NOMLE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.50	298	168	15	273	553	235	495	2e-07	64.3
rs:WP_042250925	DNA topoisomerase I [Leuconostoc mesenteroides].	21.23	471	283	14	7	432	6	433	2e-07	64.3
rs:WP_022008889	DNA topoisomerase [Firmicutes bacterium CAG:646].	22.10	439	295	15	93	504	63	481	2e-07	64.3
rs:WP_004164698	DNA topoisomerase I [Leuconostoc mesenteroides].	21.23	471	283	14	7	432	6	433	2e-07	64.3
rs:WP_007823946	DNA topoisomerase I [Rhizobium sp. CF142].	25.37	469	269	23	97	510	65	507	2e-07	64.3
rs:WP_032518605	DNA topoisomerase I [Prochlorococcus marinus].	24.71	510	305	19	101	579	85	546	2e-07	64.3
rs:XP_012555024	PREDICTED: DNA topoisomerase 3-beta-1-like [Hydra vulgaris].	21.42	579	378	19	4	553	3	533	2e-07	64.3
tr:X8HDT0_9FUSO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.39	527	321	21	7	504	11	478	2e-07	64.3
rs:WP_035567454	DNA topoisomerase I [Hymenobacter sp. IS2118].	20.98	529	327	17	7	505	6	473	2e-07	64.3
rs:WP_028376425	DNA topoisomerase I [Leeuwenhoekiella sp. Hel_I_48].	24.02	533	317	23	7	512	6	477	2e-07	64.3
rs:WP_032846708	DNA topoisomerase I [Fusobacterium sp. CM22].	22.39	527	321	21	7	504	14	481	2e-07	64.3
rs:WP_022544872	hypothetical protein [Bacteroidales bacterium CF].	24.08	519	316	17	7	504	6	467	2e-07	64.3
rs:XP_002527391	prokaryotic DNA topoisomerase, putative, partial [Ricinus communis].	23.20	569	343	26	10	534	9	527	2e-07	64.3
rs:WP_033979244	DNA topoisomerase I, partial [Pseudomonas aeruginosa].	27.34	267	164	11	99	355	76	322	2e-07	63.2
rs:WP_002828944	DNA topoisomerase I [Weissella paramesenteroides].	21.81	454	291	19	7	427	5	427	2e-07	64.3
rs:WP_024655075	DNA topoisomerase I [Borrelia hispanica].	22.92	602	350	24	7	561	7	541	2e-07	64.3
rs:WP_040236860	DNA topoisomerase I [Borrelia crocidurae].	23.38	603	346	26	7	561	7	541	2e-07	64.3
tr:I1Q1J5_ORYGL	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	26.11	314	189	11	47	335	314	609	2e-07	64.7
rs:WP_016121776	DNA topoisomerase 3, partial [Bacillus cereus].	30.00	130	76	4	430	548	1	126	2e-07	63.2
rs:WP_018788790	DNA topoisomerase I [Micromonospora sp. CNB394].	22.22	639	370	27	7	584	11	583	2e-07	64.3
rs:XP_008415641	PREDICTED: DNA topoisomerase 3-beta-1 [Poecilia reticulata].	24.92	297	172	14	273	553	279	540	2e-07	64.3
tr:E5VI15_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.80	535	316	24	7	504	6	480	3e-07	64.3
rs:WP_041771013	DNA topoisomerase I, partial [Liberibacter crescens].	24.23	549	307	28	7	505	4	493	3e-07	64.3
tr:L0EVH2_LIBCB	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.23	549	307	28	7	505	4	493	3e-07	64.3
tr:A0A0E0G6J7_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA02G17860.3};	23.87	511	312	18	47	504	304	790	3e-07	64.3
rs:XP_007801474	hypothetical protein EPUS_08478 [Endocarpon pusillum Z07020].	24.19	554	343	23	7	528	6	514	3e-07	63.9
tr:A0A0E0A850_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OGLUM06G11680.1};	26.11	314	189	11	47	335	314	609	3e-07	64.3
rs:WP_036464620	DNA topoisomerase I [Mycoplasma sturni].	22.75	523	324	23	5	504	6	471	3e-07	63.9
rs:WP_024285812	DNA topoisomerase I [Cellulomonas sp. KRMCY2].	22.08	453	292	14	7	431	8	427	3e-07	64.3
tr:A0A090BFX1_KLUMA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.49	294	178	12	279	538	306	589	3e-07	63.9
rs:WP_032825422	topoisomerase I, partial [Oenococcus oeni].	27.88	165	102	6	281	435	15	172	3e-07	60.8
tr:A0A0E0HP22_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA06G12620.1};	26.11	314	189	11	47	335	314	609	3e-07	64.3
rs:WP_035163807	topoisomerase I [Lactobacillus crispatus].	23.10	342	231	12	7	335	6	328	3e-07	64.3
rs:WP_032810567	topoisomerase I, partial [Oenococcus oeni].	31.85	135	73	4	213	339	1	124	3e-07	60.8
rs:XP_004400575	PREDICTED: DNA topoisomerase 3-beta-1 [Odobenus rosmarus divergens].	25.41	303	173	15	270	555	276	542	3e-07	64.3
tr:A0A060T6F5_BLAAD	SubName: Full=ARAD1B11726p {ECO:0000313|EMBL:CDP36384.1};	22.97	579	366	23	7	550	3	536	3e-07	63.9
rs:WP_013283654	MULTISPECIES: DNA topoisomerase I [Micromonospora].	22.58	558	329	23	7	505	11	524	3e-07	64.3
tr:A0A068BCF9_COCNU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.50	586	355	25	10	546	17	546	3e-07	64.3
tr:A6VX57_MARMS	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.88	544	339	18	7	505	6	508	3e-07	63.9
rs:WP_007390460	DNA topoisomerase I [Megasphaera sp. UPII 199-6].	22.74	532	325	19	7	504	56	535	3e-07	63.9
rs:WP_005727291	topoisomerase I [Lactobacillus crispatus].	23.10	342	231	12	7	335	6	328	3e-07	63.9
tr:D1NG17_HAEIF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	30.88	136	78	5	220	340	163	297	3e-07	62.4
rs:WP_030503757	DNA topoisomerase I [Micromonospora purpureochromogenes].	22.58	558	329	23	7	505	11	524	3e-07	63.9
rs:WP_046783662	topoisomerase I, partial [Lactobacillus plantarum].	31.11	135	74	4	213	339	1	124	3e-07	60.5
rs:WP_036450443	hypothetical protein, partial [Mycoplasma molare].	23.44	448	277	20	91	504	62	477	3e-07	63.9
rs:WP_022249372	DNA topoisomerase [Eubacterium sp. CAG:274].	23.20	431	283	16	93	500	65	470	3e-07	63.9
tr:Q3EJD1_BACTI	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EAO51420.1}; EC=5.99.1.2 {ECO:0000313|EMBL:EAO51420.1};	28.57	161	96	3	43	195	46	195	3e-07	61.6
tr:D8LDU2_ECTSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	27.04	318	184	12	48	335	130	429	3e-07	64.3
tr:F9WNV5_TRYVY	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.99	435	286	18	86	498	39	446	3e-07	63.9
rs:WP_043720005	DNA topoisomerase I [Kutzneria sp. 744].	22.53	546	343	17	7	505	23	535	3e-07	63.9
rs:WP_006518469	DNA topoisomerase I [Leptolyngbya sp. PCC 7375].	23.46	503	296	17	101	566	84	534	3e-07	63.9
rs:WP_013473584	DNA topoisomerase I [Micromonospora sp. L5].	22.58	558	329	23	7	505	11	524	3e-07	63.9
tr:T2MI56_HYDVU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	21.24	579	379	19	4	553	11	541	3e-07	63.9
rs:WP_009204281	DNA topoisomerase I [Anaerostipes hadrus].	23.13	536	313	27	7	504	6	480	3e-07	63.9
rs:XP_003862289	DNA topoisomerase III, putative [Leishmania donovani].	23.53	306	202	9	256	553	250	531	3e-07	63.9
tr:X1A8P3_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_S02335 {ECO:0000313|EMBL:GAG78049.1}; Flags: Fragment;	27.04	233	126	8	7	236	6	197	3e-07	61.2
rs:XP_008807899	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Phoenix dactylifera].	22.53	577	336	24	10	534	17	534	3e-07	63.9
rs:XP_008807898	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Phoenix dactylifera].	22.53	577	336	24	10	534	17	534	3e-07	63.9
rs:XP_001470217	putative DNA topoisomerase III [Leishmania infantum JPCM5].	23.86	306	201	10	256	553	250	531	4e-07	63.9
tr:T1BKU1_9ZZZZ	SubName: Full=DNA topoisomerase I {ECO:0000313|EMBL:EQD53929.1};	23.78	534	325	18	7	505	24	510	4e-07	63.9
rs:WP_032882171	DNA topoisomerase I [Fusobacterium nucleatum].	22.26	521	329	20	7	504	11	478	4e-07	63.9
rs:WP_010324337	topoisomerase I [Marinobacterium stanieri].	22.32	475	307	18	69	512	79	522	4e-07	63.9
tr:A0A090SHM2_9VIBR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAL27225.1}; EC=5.99.1.2 {ECO:0000313|EMBL:GAL27225.1};	30.58	121	74	4	8	126	6	118	4e-07	60.1
rs:WP_035623890	DNA topoisomerase I, partial [Lachnospiraceae bacterium C6A11].	22.12	529	322	20	7	504	6	475	4e-07	63.5
rs:WP_046420055	hypothetical protein [Xylella fastidiosa].	31.45	124	80	4	217	336	2	124	4e-07	60.1
rs:XP_005745891	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X2 [Pundamilia nyererei].	22.18	595	355	27	7	553	6	540	4e-07	63.9
tr:B8AHL0_ORYSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.01	583	342	21	36	562	162	699	4e-07	63.9
rs:WP_022091340	DNA topoisomerase [Lachnospiraceae bacterium CAG:25].	22.80	535	316	24	7	504	6	480	4e-07	63.5
rs:WP_044959040	DNA topoisomerase I [Shuttleworthia sp. MSX8B].	25.31	490	281	21	93	548	63	501	4e-07	63.5
rs:XP_008807900	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Phoenix dactylifera].	22.53	577	336	24	10	534	17	534	4e-07	63.9
tr:W4YMN5_STRPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:SPU_017059-tr};	25.55	227	144	10	283	498	154	366	4e-07	63.5
rs:WP_002350969	toprim domain protein, partial [Enterococcus faecium].	32.05	156	97	5	52	205	1	149	4e-07	60.5
rs:XP_006797644	PREDICTED: DNA topoisomerase 3-beta-1-like [Neolamprologus brichardi].	21.79	592	359	25	7	553	6	538	4e-07	63.9
rs:WP_015772462	DNA topoisomerase I [Jonesia denitrificans].	21.45	564	329	20	7	505	8	522	4e-07	63.9
tr:G7JC55_MEDTR	RecName: Full=DNA topoisomerase; EC=5.99.1.2;	22.40	558	359	22	10	534	13	529	4e-07	63.9
rs:XP_009622050	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Nicotiana tomentosiformis].	21.29	559	366	19	10	534	18	536	4e-07	63.5
rs:XP_006938803	PREDICTED: DNA topoisomerase 3-beta-1 isoform X3 [Felis catus].	24.62	329	191	17	273	583	279	568	4e-07	63.5
rs:WP_038439819	DNA topoisomerase I [Fusobacterium nucleatum].	21.88	521	331	20	7	504	11	478	4e-07	63.5
rs:WP_003448703	topoisomerase I - like protein, partial [Pseudomonas aeruginosa].	24.91	277	165	9	291	553	71	318	4e-07	63.2
rs:XP_005706261	DNA topoisomerase III alpha [Galdieria sulphuraria].	23.75	501	291	21	88	544	112	565	4e-07	63.5
rs:XP_004742578	PREDICTED: DNA topoisomerase 3-beta-1 isoform X5 [Mustela putorius furo].	25.50	298	169	15	273	553	266	527	4e-07	63.5
tr:W7JI63_PLAFA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EWC74513.1};	21.95	615	358	26	8	548	9	575	4e-07	63.5
rs:WP_019433970	DNA topoisomerase I [Streptomyces sp. AA0539].	22.42	455	289	15	97	505	90	526	4e-07	63.5
rs:WP_042745307	hypothetical protein [Oenococcus oeni].	29.03	186	110	6	213	389	1	173	4e-07	60.8
rs:XP_009622049	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Nicotiana tomentosiformis].	21.29	559	366	19	10	534	18	536	4e-07	63.5
tr:D1YRD1_9FIRM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608};	23.86	482	293	20	7	466	76	505	4e-07	63.2
tr:G9KUN5_MUSPF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.33	300	171	15	273	555	279	542	4e-07	63.5
rs:XP_004742574	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Mustela putorius furo].	25.33	300	171	15	273	555	279	542	4e-07	63.5
rs:WP_041592025	DNA topoisomerase, partial [Tetragenococcus halophilus].	34.43	122	75	3	440	557	10	130	4e-07	62.0
tr:G4L412_TETHN	SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:BAK95691.1};	34.43	122	75	3	440	557	15	135	4e-07	62.0
rs:WP_004847177	DNA topoisomerase I [[Ruminococcus] torques].	22.99	448	280	18	93	504	63	481	5e-07	63.5
rs:WP_005721409	topoisomerase I [Lactobacillus crispatus].	22.81	342	232	12	7	335	6	328	5e-07	63.5
rs:WP_008039550	DNA topoisomerase I [Bartonella tamiae].	23.94	568	307	29	4	510	1	504	5e-07	63.5
rs:WP_000513605	hypothetical protein, partial [Escherichia coli].	24.94	437	254	19	7	413	6	398	5e-07	62.8
rs:WP_030526578	DNA topoisomerase I [Phycicoccus jejuensis].	22.43	544	343	18	7	505	8	517	5e-07	63.5
tr:U6D9Q2_NEOVI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	25.33	300	171	15	273	555	279	542	5e-07	63.5
rs:XP_003687892	hypothetical protein TPHA_0L01010 [Tetrapisispora phaffii CBS 4417].	22.42	611	355	24	7	546	3	565	5e-07	63.2
rs:WP_002695772	DNA topoisomerase I [Microscilla marina].	25.79	442	240	18	7	431	6	376	5e-07	63.5
tr:A0NHW6_OENOE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.03	186	110	6	213	389	3	175	5e-07	60.8
rs:WP_045716599	DNA topoisomerase III, partial [Salmonella enterica].	30.70	114	72	2	444	552	1	112	5e-07	60.5
rs:XP_010144869	PREDICTED: DNA topoisomerase 3-beta-1 [Eurypyga helias].	25.17	286	173	12	279	553	285	540	5e-07	63.5
tr:A0A0A6L9A5_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHC70204.1};	22.66	481	307	17	91	547	93	532	5e-07	63.2
tr:A0A0A6KX97_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHC36800.1};	22.66	481	307	17	91	547	93	532	5e-07	63.2
rs:XP_012713516	PREDICTED: DNA topoisomerase 3-beta-1 [Fundulus heteroclitus].	24.75	295	171	14	275	553	281	540	5e-07	63.5
tr:L0NDR6_RHISP	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.77	547	320	23	4	505	1	495	5e-07	63.5
tr:V5AV88_TRYCR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESS64730.1};	26.32	266	156	12	300	555	297	532	5e-07	63.5
rs:WP_009053944	DNA topoisomerase I [Actinomyces sp. ICM39].	23.21	560	337	21	1	505	1	522	5e-07	63.5
rs:WP_007356210	MULTISPECIES: DNA topoisomerase I [Kamptonema].	22.93	567	337	20	46	566	29	541	5e-07	63.5
rs:XP_007091145	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Panthera tigris altaica].	25.17	298	170	15	273	553	279	540	5e-07	63.2
rs:XP_004895319	PREDICTED: DNA topoisomerase 3-beta-1 [Heterocephalus glaber].	25.50	298	169	15	273	553	279	540	5e-07	63.2
tr:K4E7B0_TRYCR	SubName: Full=DNA topoisomerase III, putative {ECO:0000313|EMBL:EKG06290.1};	26.32	266	156	12	300	555	297	532	5e-07	63.2
tr:A0A0E0NET5_ORYRU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORUFI02G17070.1};	23.45	516	313	17	47	504	257	748	5e-07	63.5
rs:WP_037399481	DNA topoisomerase I [Sinorhizobium fredii].	22.92	554	316	24	4	505	1	495	5e-07	63.2
tr:W7BLI4_LISGR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	29.81	161	95	5	198	346	30	184	5e-07	60.5
rs:XP_002970788	hypothetical protein SELMODRAFT_94303 [Selaginella moellendorffii].	23.66	465	292	19	96	534	97	524	6e-07	63.2
rs:WP_036159917	DNA topoisomerase I [Marinomonas ushuaiensis].	20.78	539	351	16	7	505	6	508	6e-07	63.2
rs:WP_016460876	DNA topoisomerase I [Actinomyces sp. HPA0247].	23.12	558	340	22	1	505	1	522	6e-07	63.2
tr:K8BJP2_9ENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.08	307	205	11	213	505	8	303	6e-07	63.2
rs:WP_010201203	DNA topoisomerase III, partial [Pseudomonas amygdali].	34.04	94	54	3	8	101	5	90	6e-07	58.9
rs:XP_006938802	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Felis catus].	25.17	298	170	15	273	553	254	515	6e-07	63.2
rs:WP_034464002	DNA topoisomerase I [Actinomyces sp. ICM54].	23.21	560	337	21	1	505	1	522	6e-07	63.2
rs:WP_044089779	DNA topoisomerase I [Bifidobacterium reuteri].	23.98	367	201	15	7	336	6	331	6e-07	63.2
rs:WP_022423481	DNA topoisomerase [Clostridium sp. CAG:440].	34.09	88	56	2	446	532	37	123	6e-07	60.1
rs:WP_041103025	DNA topoisomerase I [Mycoplasma californicum].	22.97	518	327	20	7	504	5	470	6e-07	62.8
rs:XP_011286220	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Felis catus].	25.17	298	170	15	273	553	279	540	6e-07	63.2
rs:WP_046811133	hypothetical protein [Lactobacillus plantarum].	32.03	128	82	4	213	339	1	124	6e-07	59.7
tr:A0A0D4U5M3_YEASX	SubName: Full=Top3p {ECO:0000313|EMBL:AJV55256.1};	21.66	674	411	25	7	606	3	633	6e-07	63.2
rs:XP_007091146	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Panthera tigris altaica].	25.17	298	170	15	273	553	254	515	6e-07	63.2
rs:WP_016316209	DNA topoisomerase I [Anaerotruncus sp. G3(2012)].	22.53	577	345	22	7	553	9	513	6e-07	63.2
tr:J9FBN9_WUCBA	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:EJW86992.1};	22.36	483	314	19	75	531	87	534	6e-07	63.2
rs:WP_044095969	DNA topoisomerase I, partial [Bifidobacterium reuteri].	23.98	367	201	15	7	336	6	331	6e-07	63.2
rs:WP_044921041	DNA topoisomerase I [Anaerostipes hadrus].	22.80	535	316	24	7	504	6	480	6e-07	63.2
rs:WP_008391297	DNA topoisomerase I [Clostridium sp. SS2/1].	23.09	537	312	26	7	504	6	480	6e-07	63.2
rs:WP_044441756	DNA topoisomerase I [Agreia bicolorata].	22.65	565	326	22	7	505	8	527	6e-07	63.2
gpu:CP010088_750	DNA topoisomerase family protein [Bacillus thuringiensis]	31.62	136	87	3	277	408	25	158	6e-07	59.7
tr:A0A0A4BKN3_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGU10324.1};	23.03	482	304	17	91	547	93	532	6e-07	62.8
tr:A0A0E0JZS2_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC02G14710.2};	23.25	542	341	18	47	536	390	908	6e-07	63.2
tr:W4I7S2_PLAFA	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETW39467.1};	21.95	615	358	26	8	548	9	575	6e-07	62.8
rs:WP_038561788	DNA topoisomerase I [Mycoplasma californicum].	22.97	518	327	20	7	504	5	470	6e-07	62.8
rs:XP_001684460	putative DNA topoisomerase III [Leishmania major strain Friedlin].	23.53	306	202	10	256	553	250	531	6e-07	63.2
tr:W7D7J3_9LIST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	26.79	280	162	12	257	504	19	287	6e-07	62.8
rs:XP_011780170	DNA topoisomerase III, putative [Trypanosoma brucei gambiense DAL972].	24.79	351	209	17	275	599	271	592	6e-07	63.2
rs:WP_043170112	DNA topoisomerase I [Bifidobacterium pullorum].	23.98	367	201	15	7	336	8	333	6e-07	63.2
rs:WP_045945855	DNA topoisomerase I, partial [Streptomyces katrae].	23.33	463	269	18	7	430	15	430	6e-07	62.4
rs:XP_002672722	predicted protein [Naegleria gruberi].	22.80	465	305	12	107	553	133	561	7e-07	63.2
rs:WP_036450838	DNA topoisomerase I [Mycoplasma opalescens].	24.07	457	295	18	86	517	57	486	7e-07	62.8
rs:WP_005724842	topoisomerase I [Lactobacillus crispatus].	22.81	342	232	12	7	335	6	328	7e-07	63.2
rs:XP_005391746	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Chinchilla lanigera].	25.50	298	169	15	273	553	279	540	7e-07	63.2
tr:K1SEB5_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC55898.1}; Flags: Fragment;	30.90	178	111	8	7	180	6	175	7e-07	60.1
rs:WP_034056250	DNA topoisomerase I [Pseudomonas aeruginosa].	21.77	487	311	13	69	541	73	503	7e-07	63.2
tr:M1PXL0_9VIRU	SubName: Full=Topoisomerase 1 {ECO:0000313|EMBL:AGF85502.1};	25.89	367	201	15	7	351	5	322	7e-07	62.8
rs:WP_021355722	topoisomerase I [Lactobacillus crispatus].	22.81	342	232	12	7	335	6	328	7e-07	63.2
rs:WP_033992850	hypothetical protein, partial [Pseudomonas aeruginosa].	22.58	434	272	16	98	505	70	465	7e-07	62.8
rs:WP_009905892	DNA topoisomerase [Peptoclostridium difficile].	34.75	118	68	5	7	121	4	115	7e-07	59.3
rs:YP_003969716	putative DNA topoisomerase IA [Cafeteria roenbergensis virus BV-PW1].	25.28	451	255	19	108	520	76	482	7e-07	62.8
rs:WP_022346656	DNA topoisomerase [Clostridium sp. CAG:299].	24.39	451	276	21	93	504	63	487	7e-07	62.8
rs:WP_011710863	DNA topoisomerase I [Gramella forsetii].	25.53	423	258	18	106	505	76	464	7e-07	62.8
tr:A0A0E0G6J5_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA02G17860.1};	23.45	516	313	17	47	504	304	795	7e-07	63.2
rs:WP_015370680	DNA topoisomerase I [Blattabacterium sp. (Blatta orientalis)].	24.89	442	258	18	7	437	6	384	7e-07	62.8
rs:WP_002418249	hypothetical protein, partial [Enterococcus faecalis].	41.18	85	42	4	5	85	3	83	7e-07	58.5
rs:WP_025743036	DNA topoisomerase I [Aquimarina sp. SW150].	25.73	447	262	20	103	517	73	481	7e-07	62.8
rs:WP_028567975	DNA topoisomerase I [Salinispora tropica].	23.79	454	266	20	107	505	96	524	7e-07	62.8
tr:A0A0A6KR82_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHC63786.1};	22.66	481	307	17	91	547	93	532	7e-07	62.8
tr:A4MY78_HAEIF	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EDJ88970.1};	28.57	147	95	4	8	150	5	145	7e-07	59.7
rs:WP_021816160	hypothetical protein [Lactobacillus fermentum].	34.23	111	65	5	5	112	3	108	7e-07	58.9
rs:WP_042771766	hypothetical protein [Streptococcus sp. HSISS3].	39.29	84	47	2	41	124	2	81	7e-07	58.9
tr:A0A0E0JZS4_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC02G14710.4};	23.73	510	314	18	47	504	390	876	7e-07	63.2
rs:WP_001689523	toprim domain protein, partial [Escherichia coli].	29.55	132	84	5	8	137	5	129	7e-07	59.3
rs:WP_000317025	DNA topoisomerase I subunit omega, partial [Escherichia coli].	26.14	264	160	10	262	505	12	260	7e-07	62.8
tr:A0A0A4C665_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGU31296.1};	22.66	481	307	17	91	547	93	532	7e-07	62.8
tr:A0A0A6J0T3_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHC42614.1};	22.66	481	307	17	91	547	93	532	7e-07	62.8
rs:WP_022035402	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:50].	24.93	337	208	14	198	504	15	336	8e-07	62.4
tr:A0A0A3CMN4_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGQ98297.1};	22.66	481	307	17	91	547	93	532	8e-07	62.8
rs:YP_002049366	DNA topoisomerase I [Paulinella chromatophora].	23.52	472	292	16	77	505	62	507	8e-07	62.8
rs:WP_000520735	hypothetical protein, partial [Bacillus thuringiensis].	27.78	198	130	5	5	195	4	195	8e-07	60.1
rs:WP_027378935	DNA topoisomerase I [Chryseobacterium daeguense].	22.41	522	317	23	7	504	6	463	8e-07	62.8
tr:C3WNT3_FUSNV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.88	521	331	20	7	504	14	481	8e-07	62.8
rs:WP_028570813	DNA topoisomerase I [Salinispora tropica].	23.79	454	266	20	107	505	96	524	8e-07	62.8
rs:WP_025902220	hypothetical protein, partial [Tatumella sp. UCD-D_suzukii].	23.18	289	173	8	5	291	3	244	8e-07	60.5
rs:WP_044593298	hypothetical protein [Cronobacter sakazakii].	35.90	78	50	0	462	539	17	94	8e-07	59.7
rs:WP_027585179	DNA topoisomerase I [Prolixibacter bellariivorans].	22.75	523	320	20	7	504	6	469	8e-07	62.8
rs:XP_812670	DNA topoisomerase IA [Trypanosoma cruzi strain CL Brener].	24.26	404	236	16	97	449	118	502	8e-07	62.8
tr:F0WSH2_9STRA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.15	641	384	25	7	593	6	585	8e-07	62.8
tr:X2HCF0_9GAMM	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AHN27266.1}; EC=5.99.1.2 {ECO:0000313|EMBL:AHN27266.1};	36.27	102	59	2	444	539	1	102	8e-07	58.9
tr:A0A0A6K2P4_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHC55676.1};	22.66	481	307	17	91	547	93	532	8e-07	62.4
tr:J6B175_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJX75617.1}; Flags: Fragment;	30.26	152	95	3	422	563	1	151	8e-07	59.3
rs:WP_022398991	GTP-sensing transcriptional pleiotropic repressor CodY [Roseburia sp. CAG:471].	24.11	448	275	20	93	504	63	481	8e-07	62.8
tr:H2MSA1_ORYLA	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.44	287	170	13	283	555	296	552	8e-07	62.8
rs:WP_044998796	hypothetical protein, partial [Coprococcus comes].	22.19	347	236	13	91	424	6	331	8e-07	62.4
rs:WP_012015225	MULTISPECIES: DNA topoisomerase I [Salinispora].	23.79	454	266	20	107	505	96	524	8e-07	62.8
gpu:CP009928_1108	DNA topoisomerase I [Chryseobacterium gallinarum]	21.48	526	317	23	7	504	6	463	8e-07	62.8
rs:WP_038102482	DNA topoisomerase I [Ureaplasma diversum].	23.61	466	300	18	107	545	81	517	9e-07	62.4
rs:XP_005391751	PREDICTED: DNA topoisomerase 3-beta-1 isoform X6 [Chinchilla lanigera].	25.50	298	169	15	273	553	182	443	9e-07	62.4
rs:WP_035315918	hypothetical protein, partial [Brochothrix campestris].	29.10	134	82	3	331	458	1	127	9e-07	58.9
tr:A0A0A3CE31_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGQ92393.1};	22.66	481	307	17	91	547	93	532	9e-07	62.4
rs:WP_032843600	DNA topoisomerase I [Fusobacterium nucleatum].	21.88	521	331	20	7	504	11	478	9e-07	62.4
rs:WP_046242733	DNA topoisomerase I [Hymenobacter sp. MIMtkLc17].	21.05	532	323	20	7	505	6	473	9e-07	62.4
rs:WP_013796385	topoisomerase I [Marinomonas posidonica].	20.91	617	394	21	7	584	6	567	9e-07	62.4
rs:WP_013103637	MULTISPECIES: DNA topoisomerase I [Leuconostoc].	22.35	452	301	15	7	432	6	433	9e-07	62.4
rs:WP_033505463	DNA topoisomerase I [Bifidobacterium gallinarum].	23.98	367	201	15	7	336	8	333	9e-07	62.8
rs:WP_012623949	DNA topoisomerase I [Desulfovibrio desulfuricans].	25.67	448	270	17	91	505	61	478	9e-07	62.4
rs:XP_003493773	PREDICTED: DNA topoisomerase 3-beta-1 [Bombus impatiens].	22.43	428	279	18	97	498	101	501	9e-07	62.4
rs:WP_033508168	DNA topoisomerase I [Bifidobacterium saeculare].	23.98	367	201	15	7	336	8	333	9e-07	62.8
rs:WP_015132934	DNA topoisomerase I [Leptolyngbya sp. PCC 7376].	22.99	448	289	13	95	505	78	506	9e-07	62.4
rs:WP_034055413	hypothetical protein, partial [Pseudomonas aeruginosa].	22.35	434	273	17	98	505	70	465	9e-07	62.4
rs:NP_001006181	DNA topoisomerase 3-beta-1 [Gallus gallus].	22.11	588	364	26	7	553	6	540	9e-07	62.4
rs:WP_023566947	DNA topoisomerase I, partial [Escherichia coli].	26.14	264	160	10	262	505	8	256	1e-06	62.0
rs:WP_028702223	DNA topoisomerase I [Propionibacterium jensenii].	25.07	359	208	15	5	336	6	330	1e-06	62.4
tr:H8H3H1_DEIGI	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	23.84	432	267	15	109	505	91	495	1e-06	62.4
tr:Q7P6B1_FUSNV	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.88	521	331	20	7	504	14	481	1e-06	62.4
tr:M3HDJ8_LEPIT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.73	451	275	16	7	440	5	403	1e-06	61.6
rs:WP_021985356	DNA topoisomerase [Clostridium sp. CAG:127].	23.45	435	279	14	97	505	67	473	1e-06	62.4
rs:WP_026889209	DNA topoisomerase I [Clostridium beijerinckii].	22.96	527	325	20	7	505	6	479	1e-06	62.4
tr:A0A0E0JZS6_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC02G14710.6};	23.73	510	314	18	47	504	390	876	1e-06	62.8
tr:A0A086FA68_9FLAO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.44	527	318	23	7	505	6	464	1e-06	62.4
rs:WP_034701543	DNA topoisomerase I [Chryseobacterium luteum].	21.95	524	317	22	7	504	6	463	1e-06	62.4
rs:WP_000054704	DNA topoisomerase I, partial [Leptospira interrogans].	23.73	451	275	16	7	440	5	403	1e-06	61.6
rs:WP_045722854	DNA topoisomerase I, partial [Salmonella enterica].	25.41	362	201	14	7	339	6	327	1e-06	61.2
tr:A0A0E0JZS5_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC02G14710.5};	23.73	510	314	18	47	504	390	876	1e-06	62.4
tr:A0A0A3C6T3_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGQ88087.1};	22.45	481	308	17	91	547	93	532	1e-06	62.0
rs:XP_010674422	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Beta vulgaris subsp. vulgaris].	22.95	584	323	25	10	534	14	529	1e-06	62.4
rs:WP_021944413	DNA topoisomerase [Clostridium sp. CAG:264].	21.60	537	322	25	7	505	45	520	1e-06	62.4
tr:W2TUU8_NECAM	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.07	349	216	16	217	553	266	577	1e-06	62.4
tr:A0A0E0G6J6_ORYNI	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ONIVA02G17860.2};	23.45	516	313	17	47	504	304	795	1e-06	62.4
rs:XP_010674423	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Beta vulgaris subsp. vulgaris].	22.95	584	323	25	10	534	14	529	1e-06	62.4
rs:XP_002785799	DNA topoisomerase 3-beta-1, putative [Perkinsus marinus ATCC 50983].	19.70	462	318	16	107	555	112	533	1e-06	62.4
tr:A7VIM6_9CLOT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.64	536	321	25	7	504	37	511	1e-06	62.0
rs:WP_031887220	DNA topoisomerase III, partial [Staphylococcus aureus].	34.41	93	60	1	452	544	1	92	1e-06	60.1
tr:A0A0A4BUN0_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGU27326.1};	22.25	481	309	17	91	547	93	532	1e-06	62.0
tr:A0A0A6KY88_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHC37170.1};	23.33	480	305	17	91	547	93	532	1e-06	62.0
tr:A0A0B0HVB4_9BACL	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:KHF32527.1}; EC=5.99.1.2 {ECO:0000313|EMBL:KHF32527.1};	25.61	164	91	2	395	544	3	149	1e-06	61.2
rs:WP_020789377	DNA topoisomerase I [Fusobacterium nucleatum].	21.88	521	331	20	7	504	11	478	1e-06	62.0
rs:XP_003675634	hypothetical protein NCAS_0C02780 [Naumovozyma castellii CBS 4309].	21.43	616	367	26	7	546	3	577	1e-06	62.0
tr:A0A0A3DLK3_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGR10128.1};	22.45	481	308	17	91	547	93	532	1e-06	62.0
rs:WP_003506900	DNA topoisomerase I [[Clostridium] symbiosum].	22.77	448	283	18	93	504	63	483	1e-06	62.0
tr:A0A0A6JT51_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KHC52303.1};	22.45	481	308	17	91	547	93	532	1e-06	62.0
tr:A0A0B7A5F1_9EUPU	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	22.63	495	331	17	88	569	115	570	1e-06	62.4
tr:G0U5I3_TRYVY	SubName: Full=Putative DNA topoisomerase IA {ECO:0000313|EMBL:CCC51134.1};	24.13	402	239	16	97	449	123	507	1e-06	62.0
tr:W7ZTL7_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAF20066.1};	26.51	166	111	4	376	531	19	183	1e-06	61.2
tr:K2DHP7_9BACT	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EKE05216.1}; Flags: Fragment;	26.32	190	116	6	162	344	10	182	1e-06	59.3
tr:C4YQM8_CANAW	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEQ44517.1};	22.45	481	308	17	91	547	93	532	1e-06	62.0
rs:WP_038371482	DNA topoisomerase I [Fusobacterium nucleatum].	21.88	521	331	20	7	504	11	478	1e-06	62.0
rs:WP_021588432	DNA topoisomerase I [Prevotella baroniae].	24.43	438	253	15	7	430	6	379	1e-06	62.0
rs:WP_020515364	DNA topoisomerase I [Actinoplanes globisporus].	23.43	572	327	25	7	512	11	537	1e-06	62.4
tr:A0A0A4AHV5_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGU10901.1};	22.45	481	308	17	91	547	93	532	1e-06	62.0
rs:WP_003797196	DNA topoisomerase I [Actinomyces odontolyticus].	23.21	560	337	21	1	505	1	522	1e-06	62.0
rs:WP_003791882	DNA topoisomerase I [Actinomyces odontolyticus].	23.21	560	337	21	1	505	1	522	1e-06	62.0
rs:WP_014324310	DNA topoisomerase I [Leuconostoc mesenteroides].	21.02	471	284	14	7	432	6	433	1e-06	62.0
rs:WP_019793773	hypothetical protein, partial [Streptococcus sobrinus].	26.71	307	169	14	7	305	33	291	1e-06	60.8
tr:C0BCS1_9FIRM	SubName: Full=Putative DNA topoisomerase {ECO:0000313|EMBL:EEG88872.1};	22.19	347	236	13	91	424	291	616	1e-06	62.0
rs:XP_723146	likely DNA topoisomerase III [Candida albicans SC5314].	22.45	481	308	17	91	547	93	532	1e-06	62.0
rs:WP_035416420	DNA topoisomerase III, partial [Bacillus sp. MB2021].	30.67	163	91	6	386	546	14	156	1e-06	60.8
rs:WP_040746384	DNA topoisomerase III, partial [alpha proteobacterium BAL199].	31.93	119	72	3	441	552	6	122	1e-06	61.2
tr:A0A0A4BNW5_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGU11439.1};	22.45	481	308	17	91	547	93	532	1e-06	62.0
tr:K2ADJ5_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	24.09	440	269	13	97	495	66	481	1e-06	62.0
tr:A0A0E0NQ37_ORYRU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORUFI03G04550.1};	22.53	586	343	25	10	546	17	540	1e-06	62.0
rs:WP_043805158	hypothetical protein, partial [Deinococcus gobiensis].	23.49	430	271	14	109	505	91	495	1e-06	62.0
tr:A0A075JPQ3_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:AIF42093.1};	26.67	195	125	5	417	602	9	194	1e-06	60.8
tr:F3EUA5_PSEA0	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	22.03	395	265	12	129	505	1	370	1e-06	62.0
rs:WP_009298158	MULTISPECIES: DNA topoisomerase I [Clostridiales].	23.39	449	279	20	93	504	63	483	1e-06	62.0
rs:WP_035837563	DNA topoisomerase I [Cryobacterium roopkundense].	22.76	558	336	19	7	505	8	529	1e-06	62.0
rs:WP_025267775	DNA topoisomerase I [Leuconostoc mesenteroides].	21.02	471	284	14	7	432	6	433	1e-06	62.0
rs:WP_045756029	DNA topoisomerase I, partial [Sphingobacterium sp. PM2-P1-29].	24.10	332	209	8	198	505	4	316	1e-06	62.0
rs:WP_004462358	DNA topoisomerase I [[Clostridium] symbiosum].	23.39	449	279	20	93	504	63	483	1e-06	62.0
tr:X0ZUF0_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S01H4_C03794 {ECO:0000313|EMBL:GAG61602.1};	26.81	138	91	2	204	341	36	163	1e-06	58.9
tr:W4RQI6_9BACI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:GAE46705.1};	29.13	127	82	1	107	233	28	146	1e-06	58.5
rs:WP_021746945	DNA topoisomerase I [Leptotrichia wadei].	21.80	532	316	18	7	504	6	471	1e-06	62.0
rs:WP_025755476	DNA topoisomerase I [Mycoplasma cricetuli].	21.35	548	334	24	1	513	1	486	1e-06	61.6
tr:A0A077XXA7_9SPHI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.10	332	209	8	198	505	2	314	1e-06	61.6
rs:WP_045749618	DNA topoisomerase I [Acholeplasma oculi].	24.34	530	323	22	26	540	12	478	1e-06	61.6
tr:I1P7W6_ORYGL	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.67	591	349	26	10	546	17	553	1e-06	62.0
tr:N6UAY1_DENPD	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	23.97	459	291	19	89	530	92	509	1e-06	62.0
rs:WP_025063001	DNA topoisomerase I [Sulfitobacter guttiformis].	24.76	521	292	24	4	492	1	453	1e-06	62.0
rs:WP_005976360	DNA topoisomerase I [Fusobacterium ulcerans].	22.74	519	327	20	7	504	7	472	1e-06	62.0
rs:XP_006877695	PREDICTED: DNA topoisomerase 3-beta-1 [Chrysochloris asiatica].	24.92	301	177	14	270	555	276	542	1e-06	62.0
rs:WP_008646106	hypothetical protein, partial [Bacteroides sp. 1_1_30].	24.32	222	145	5	379	592	40	246	1e-06	61.2
rs:WP_011817947	DNA topoisomerase I [Prochlorococcus marinus].	24.61	512	303	19	101	579	85	546	1e-06	62.0
rs:XP_816014	DNA topoisomerase III [Trypanosoma cruzi strain CL Brener].	22.82	561	350	27	10	539	9	517	1e-06	62.0
rs:WP_030151791	DNA topoisomerase I [Oerskovia turbata].	23.47	375	221	13	7	349	8	348	1e-06	62.0
rs:XP_001614250	DNA topoisomerase III alpha [Plasmodium vivax Sal-1].	25.48	259	156	10	283	531	331	562	1e-06	61.6
rs:WP_044946190	DNA topoisomerase I [Clostridium sp. L2-50].	21.60	537	322	25	7	505	6	481	1e-06	61.6
tr:F3IVS0_PSEAP	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	23.27	391	253	14	135	505	4	367	1e-06	62.0
tr:I1GZ20_BRADI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	24.02	533	324	20	36	510	76	585	1e-06	62.0
tr:K2FXV5_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.22	286	164	10	89	348	58	322	1e-06	61.6
tr:B1NNY5_STREQ	SubName: Full=Truncated topoisomerase {ECO:0000313|EMBL:ACA42500.1}; Flags: Fragment;	28.38	148	98	4	81	225	4	146	1e-06	58.5
rs:WP_010197905	DNA topoisomerase I, partial [Pseudomonas amygdali].	22.11	389	260	12	135	505	4	367	2e-06	61.6
rs:WP_022083390	DNA topoisomerase [Bacteroides sp. CAG:144].	23.50	400	247	12	133	505	11	378	2e-06	61.6
tr:T3QTH0_PEPDI	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EQG76222.1};	34.75	118	68	5	7	121	4	115	2e-06	58.2
tr:A4L2X4_LACRE	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	24.54	273	154	9	7	275	25	249	2e-06	59.7
rs:WP_006906309	DNA topoisomerase I [Shuttleworthia satelles].	23.77	488	291	19	93	548	63	501	2e-06	61.6
rs:WP_025663347	DNA topoisomerase I [Aquimarina megaterium].	24.28	523	306	20	7	504	6	463	2e-06	61.6
rs:WP_008697687	DNA topoisomerase I [Fusobacterium ulcerans].	22.74	519	327	20	7	504	7	472	2e-06	61.6
tr:J6XY22_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJY30884.1}; Flags: Fragment;	30.26	152	95	3	422	563	1	151	2e-06	59.7
tr:C2D5U6_LACBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	31.25	128	83	3	213	339	1	124	2e-06	58.5
tr:B9EZZ0_ORYSJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.75	522	321	18	36	504	162	659	2e-06	61.6
rs:XP_007048481	Topoisomerase 3alpha isoform 2, partial [Theobroma cacao].	22.13	583	350	23	1	534	1	528	2e-06	61.6
rs:XP_008667757	PREDICTED: hypothetical protein isoform X2 [Zea mays].	21.23	570	374	22	10	546	16	543	2e-06	61.6
rs:WP_031757110	hypothetical protein, partial [Pseudomonas aeruginosa].	22.35	434	273	16	98	505	70	465	2e-06	61.6
tr:A0A0E0NQ40_ORYRU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:ORUFI03G04550.4};	22.65	574	333	25	10	534	17	528	2e-06	61.6
rs:WP_008424783	DNA topoisomerase I [Clostridium sp. Maddingley MBC34-26].	24.52	526	318	22	7	505	6	479	2e-06	61.6
rs:WP_013618934	DNA topoisomerase I [Bacteroides salanitronis].	23.53	527	307	24	7	504	6	465	2e-06	61.6
rs:WP_002348935	DNA topoisomerase, partial [Enterococcus faecium].	25.91	193	132	5	165	356	24	206	2e-06	58.9
rs:WP_032973207	DNA topoisomerase I, partial [Stenotrophomonas maltophilia].	26.42	246	137	8	7	247	6	212	2e-06	58.9
rs:XP_008667755	PREDICTED: hypothetical protein isoform X1 [Zea mays].	21.23	570	374	22	10	546	16	543	2e-06	61.6
rs:WP_006593989	DNA topoisomerase I [Kineosphaera limosa].	22.58	558	334	22	7	505	10	528	2e-06	61.6
tr:G3NI54_GASAC	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518}; Flags: Fragment;	24.65	288	165	14	283	553	283	535	2e-06	61.6
rs:WP_034073375	hypothetical protein, partial [Pseudomonas aeruginosa].	22.35	434	273	17	98	505	70	465	2e-06	61.2
rs:WP_033694421	DNA topoisomerase, partial [Bacillus thuringiensis].	27.52	149	96	4	198	342	30	170	2e-06	58.9
tr:L9LCG8_TUPCH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.42	295	163	15	284	555	366	626	2e-06	61.6
tr:B8B0L7_ORYSI	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.98	252	149	8	107	335	376	615	2e-06	61.6
rs:WP_032825101	topoisomerase I, partial [Oenococcus oeni].	29.80	151	93	5	423	563	1	148	2e-06	59.3
tr:A0A0A8LDJ3_9SACH	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	23.26	473	290	21	107	539	111	550	2e-06	61.2
rs:WP_022304720	DNA topoisomerase [Firmicutes bacterium CAG:227].	24.19	430	269	16	107	504	77	481	2e-06	61.2
rs:WP_042159536	hypothetical protein, partial [Pseudomonas aeruginosa].	22.35	434	273	17	98	505	70	465	2e-06	61.2
rs:NP_001120391	DNA topoisomerase 3-beta-1 isoform 2 [Xenopus (Silurana) tropicalis].	22.63	358	213	17	216	553	214	527	2e-06	61.6
tr:F7ES60_XENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.63	358	213	17	216	553	227	540	2e-06	61.6
tr:X1KLC0_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_L05690 {ECO:0000313|EMBL:GAI07872.1}; Flags: Fragment;	27.63	228	137	9	107	322	1	212	2e-06	59.3
rs:WP_031633366	hypothetical protein, partial [Pseudomonas aeruginosa].	22.35	434	273	17	98	505	70	465	2e-06	61.2
rs:WP_034073736	hypothetical protein, partial [Pseudomonas aeruginosa].	22.35	434	273	17	98	505	70	465	2e-06	61.2
rs:WP_022124364	DNA topoisomerase [Clostridium sp. CAG:510].	23.93	443	281	20	93	504	102	519	2e-06	61.2
rs:WP_027634208	DNA topoisomerase I [Clostridium hydrogeniformans].	22.71	524	330	19	7	505	6	479	2e-06	61.2
rs:XP_003877019	putative DNA topoisomerase III [Leishmania mexicana MHOM/GT/2001/U1103].	23.53	306	202	10	256	553	250	531	2e-06	61.6
rs:WP_031655094	hypothetical protein, partial [Pseudomonas aeruginosa].	22.35	434	273	16	98	505	70	465	2e-06	61.2
tr:A0A073IAQ6_9PORP	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KEJ87403.1};	26.03	146	102	3	8	153	5	144	2e-06	58.2
rs:NP_001182501	DNA topoisomerase 3-beta-1 isoform 1 [Xenopus (Silurana) tropicalis].	22.63	358	213	17	216	553	227	540	2e-06	61.2
rs:WP_016483699	DNA topoisomerase I [Chthonomonas calidirosea].	22.98	483	307	17	80	517	48	510	2e-06	61.2
tr:F6X812_XENTR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.63	358	213	17	216	553	216	529	2e-06	61.2
gp:HG974234_6437	DNA topoisomerase I, plasmid [Pseudomonas aeruginosa]	22.35	434	273	17	98	505	70	465	2e-06	61.2
tr:V2BQG0_SALDE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Fragment;	24.65	357	204	13	7	336	6	324	2e-06	60.5
rs:XP_004182129	hypothetical protein TBLA_0H03290 [Tetrapisispora blattae CBS 6284].	22.47	632	385	24	7	569	3	598	2e-06	61.2
tr:A0A0E0LAF6_ORYPU	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OPUNC06G10370.1};	26.98	252	149	8	107	335	380	619	2e-06	61.6
tr:W0WM01_PSEAI	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CDH72766.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CDH72766.1};	41.18	68	38	1	485	552	2	67	2e-06	58.2
rs:WP_031840281	DNA topoisomerase III, partial [Vibrio parahaemolyticus].	28.14	167	98	7	8	161	6	163	2e-06	58.2
tr:A0A0A4C4G6_CANAX	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:KGU30711.1};	22.25	481	309	17	91	547	93	532	2e-06	61.2
rs:XP_007513275	predicted protein [Bathycoccus prasinos].	24.17	331	193	13	251	555	319	617	2e-06	61.2
rs:XP_007906923	PREDICTED: DNA topoisomerase 3-beta-1 [Callorhinchus milii].	23.43	286	168	13	283	553	290	539	2e-06	61.2
tr:B7BDS5_9PORP	SubName: Full=Toprim domain protein {ECO:0000313|EMBL:EEC95424.1};	30.97	155	92	5	4	150	1	148	2e-06	58.2
rs:WP_014850163	DNA topoisomerase I [Mycoplasma wenyonii].	24.46	507	315	23	45	504	19	504	2e-06	61.2
tr:A0A0D3GFC0_9ORYZ	SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:OBART06G10800.1};	26.98	252	149	8	107	335	376	615	2e-06	61.2
rs:WP_010722045	hypothetical protein [Enterococcus faecium].	40.00	85	43	4	5	85	3	83	2e-06	57.4
tr:J2MMG4_9PSED	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00046608}; Flags: Precursor;	22.88	459	301	16	7	442	6	434	2e-06	60.8
gp:CP002034_557	DNA topoisomerase [Lactobacillus salivarius CECT 5713]	27.97	236	128	9	7	240	21	216	2e-06	58.5
tr:A3BAP2_ORYSJ	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.98	252	149	8	107	335	376	615	2e-06	61.2
rs:XP_002985109	hypothetical protein SELMODRAFT_121488 [Selaginella moellendorffii].	23.44	465	293	19	96	534	97	524	2e-06	61.2
rs:XP_819023	DNA topoisomerase III [Trypanosoma cruzi strain CL Brener].	25.48	263	162	11	300	555	297	532	2e-06	61.2
rs:WP_011849798	DNA topoisomerase [Pyrobaculum calidifontis].	20.35	565	369	19	7	544	4	514	2e-06	60.8
rs:WP_044069760	hypothetical protein [Pseudomonas aeruginosa].	22.35	434	273	16	98	505	70	465	2e-06	60.8
rs:WP_013140081	DNA topoisomerase I [Bifidobacterium longum].	23.98	367	201	15	7	336	6	331	2e-06	61.2
rs:XP_010700529	DNA topoisomerase III, putative [Leishmania panamensis].	24.71	259	165	9	300	553	298	531	2e-06	61.2
tr:W6TIV2_9SPIO	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952, ECO:0000256|SAAS:SAAS00085286}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.47	494	300	18	107	561	14	463	2e-06	60.8
rs:WP_042093035	hypothetical protein, partial [Escherichia coli].	29.11	213	131	8	8	206	5	211	2e-06	58.5
tr:K2H0F1_9BACT	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	26.13	287	163	9	89	348	58	322	3e-06	61.2
tr:X1N1D6_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_S04005 {ECO:0000313|EMBL:GAI20685.1}; Flags: Fragment;	23.61	305	188	11	7	309	6	267	3e-06	59.3
rs:WP_039369837	DNA topoisomerase I [Chryseobacterium taiwanense].	21.26	522	323	21	7	504	6	463	3e-06	61.2
rs:WP_033892529	DNA topoisomerase I, partial [Bifidobacterium breve].	23.98	367	201	15	7	336	6	331	3e-06	60.5
rs:XP_003874672	putative DNA topoisomerase III [Leishmania mexicana MHOM/GT/2001/U1103].	22.40	317	208	11	279	585	274	562	3e-06	61.2
rs:WP_002418302	hypothetical protein, partial [Enterococcus faecalis].	28.89	135	90	3	94	225	4	135	3e-06	57.8
rs:XP_006746431	PREDICTED: DNA topoisomerase 3-beta-1-like [Leptonychotes weddellii].	24.73	283	159	15	287	553	34	278	3e-06	60.8
tr:K2MRY5_TRYCR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.63	527	339	23	35	539	43	517	3e-06	60.8
tr:H2EFW7_9VIRU	SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:AEX63019.1};	25.61	367	202	15	7	351	5	322	3e-06	60.8
rs:WP_036965640	DNA topoisomerase I [Promicromonospora kroppenstedtii].	21.68	558	342	18	7	505	8	529	3e-06	60.8
rs:WP_002161842	DNA topoisomerase 1 [Bacillus cereus].	31.09	119	77	1	112	230	45	158	3e-06	57.8
tr:A0A0C5RM05_9MOLU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.81	469	298	17	107	548	81	512	3e-06	60.8
rs:WP_042226226	DNA topoisomerase I, partial [Porphyromonas cansulci].	28.80	184	114	5	4	178	1	176	3e-06	57.8
rs:WP_022430440	DNA topoisomerase III [Prevotella stercorea CAG:629].	27.84	176	108	4	375	534	1	173	3e-06	60.1
tr:D0EG00_LEIDO	SubName: Full=DNA topoisomerase III beta {ECO:0000313|EMBL:ACX31684.1};	23.20	306	203	10	256	553	250	531	3e-06	60.8
rs:XP_007048480	Topoisomerase 3alpha isoform 1 [Theobroma cacao].	22.13	583	350	23	1	534	1	528	3e-06	60.8
rs:WP_009267877	MULTISPECIES: DNA topoisomerase I [Lachnospiraceae].	23.93	514	304	23	70	548	40	501	3e-06	60.8
rs:YP_007354228	DNA topoisomerase 1 [Acanthamoeba polyphaga moumouvirus].	25.61	367	202	15	7	351	5	322	3e-06	60.8
rs:XP_009403000	PREDICTED: DNA topoisomerase 3-alpha [Musa acuminata subsp. malaccensis].	22.74	598	333	26	10	546	18	547	3e-06	60.8
rs:WP_027439327	DNA topoisomerase I [Lachnospiraceae bacterium AC2031].	22.41	531	319	22	7	504	6	476	3e-06	60.5
tr:K1S3X1_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC48415.1};	29.68	155	85	4	170	322	24	156	3e-06	58.2
rs:XP_003198651	PREDICTED: DNA topoisomerase 3-beta-1 [Danio rerio].	22.92	288	185	10	275	553	281	540	3e-06	60.8
tr:F1QNX4_DANRE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.92	288	185	10	275	553	282	541	4e-06	60.8
rs:XP_001740725	DNA topoisomerase 3-beta-1 [Entamoeba dispar SAW760].	21.33	497	332	17	107	582	109	567	4e-06	60.5
tr:X1M6J8_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S06H3_L03210 {ECO:0000313|EMBL:GAI10320.1}; Flags: Fragment;	24.17	331	204	12	7	335	1	286	4e-06	59.7
tr:K1TFM0_9ZZZZ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EKC68533.1}; Flags: Fragment;	30.61	147	92	5	7	151	5	143	4e-06	57.4
rs:WP_008820261	DNA topoisomerase, partial [Fusobacterium periodonticum].	22.92	528	317	23	7	504	14	481	4e-06	60.5
rs:XP_009841734	hypothetical protein H257_15346 [Aphanomyces astaci].	21.48	596	362	21	10	553	8	549	4e-06	60.8
rs:WP_010212659	DNA topoisomerase I, partial [Pseudomonas amygdali].	22.91	323	216	10	201	505	52	359	4e-06	60.5
tr:T0DWI7_CLOSO	SubName: Full=DNA topoisomerase family protein {ECO:0000313|EMBL:EPZ55488.1};	34.95	103	63	2	430	532	15	113	4e-06	57.0
rs:WP_022635683	DNA topoisomerase I [Chitinivibrio alkaliphilus].	23.29	541	331	19	7	512	6	497	4e-06	60.5
rs:WP_027859126	DNA topoisomerase I [Marinobacterium jannaschii].	21.08	555	351	19	7	512	6	522	4e-06	60.5
tr:J6QJD7_ENTFC	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EJX56983.1}; Flags: Fragment;	34.12	85	53	1	376	457	32	116	4e-06	57.0
rs:WP_040146912	DNA topoisomerase III, partial [Xanthomonas citri].	34.21	76	48	1	477	552	4	77	4e-06	57.8
rs:WP_025299499	DNA topoisomerase I [Bifidobacterium breve].	23.98	367	201	15	7	336	6	331	4e-06	60.5
rs:WP_016629677	hypothetical protein, partial [Enterococcus faecium].	40.00	85	43	4	5	85	3	83	4e-06	56.2
rs:WP_005950772	hypothetical protein, partial [Blautia hydrogenotrophica].	23.15	445	267	19	7	430	6	396	4e-06	59.7
tr:A0A090T1A0_9VIBR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	22.84	324	214	12	201	505	8	314	4e-06	60.5
rs:WP_040781672	DNA topoisomerase I, partial [Marvinbryantia formatexigens].	21.70	530	329	23	7	504	6	481	4e-06	60.5
rs:WP_046756567	DNA topoisomerase I [Kordia jejudonensis].	23.71	523	311	20	7	505	6	464	4e-06	60.5
rs:WP_041013033	hypothetical protein [Vibrio sp. DCR 1-4-12].	34.74	95	60	1	454	548	6	98	4e-06	57.4
rs:XP_008879534	hypothetical protein, variant [Aphanomyces invadans].	22.34	591	363	22	8	553	6	545	4e-06	60.5
rs:WP_034019142	hypothetical protein, partial [Pseudomonas aeruginosa].	22.12	434	274	17	98	505	70	465	4e-06	60.1
tr:W7CHH1_9LIST	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	25.56	266	169	10	264	504	8	269	4e-06	60.1
rs:WP_015438280	DNA topoisomerase I [Bifidobacterium breve].	23.98	367	201	15	7	336	6	331	4e-06	60.5
rs:WP_016462108	DNA topoisomerase I [Bifidobacterium breve].	23.98	367	201	15	7	336	6	331	4e-06	60.5
rs:WP_003828044	DNA topoisomerase I [Bifidobacterium breve].	23.98	367	201	15	7	336	6	331	4e-06	60.5
tr:R0MEX3_NOSB1	SubName: Full=DNA topoisomerase 3-alpha {ECO:0000313|EMBL:EOB11308.1};	24.46	507	302	23	46	532	6	451	4e-06	60.1
tr:C6L9V4_9FIRM	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	21.70	530	329	23	7	504	14	489	4e-06	60.1
rs:WP_020015843	DNA topoisomerase I [Promicromonospora sukumoe].	21.68	558	342	18	7	505	8	529	4e-06	60.5
rs:XP_005807446	PREDICTED: DNA topoisomerase 3-beta-1-like [Xiphophorus maculatus].	25.51	294	174	15	273	553	279	540	5e-06	60.5
tr:A0A097STQ1_9MOLU	RecName: Full=DNA topoisomerase 1 {ECO:0000256|HAMAP-Rule:MF_00952}; EC=5.99.1.2 {ECO:0000256|HAMAP-Rule:MF_00952}; AltName: Full=DNA topoisomerase I {ECO:0000256|HAMAP-Rule:MF_00952};	22.57	452	293	17	91	504	69	501	5e-06	60.1
rs:WP_035181400	hypothetical protein [Lactobacillus farraginis].	29.05	148	93	4	213	359	1	137	5e-06	57.0
tr:W5IAU1_WHEAT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	26.98	315	186	13	47	335	285	581	5e-06	60.1
rs:WP_034755283	DNA topoisomerase I [Chryseobacterium sp. OV259].	21.15	520	326	19	7	504	6	463	5e-06	60.1
rs:WP_036161481	hypothetical protein [Lysinibacillus sphaericus].	28.03	157	97	5	7	154	5	154	5e-06	57.0
rs:WP_021423285	toprim domain protein, partial [Peptoclostridium difficile].	30.61	147	92	6	7	151	4	142	5e-06	57.0
rs:WP_032602860	DNA topoisomerase I, partial [Bacteroides fragilis].	26.09	161	108	3	398	550	2	159	5e-06	57.8
tr:G0NRK3_CAEBE	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	21.99	532	359	18	32	548	43	533	5e-06	60.1
rs:WP_018234300	hypothetical protein [Thioalkalivibrio thiocyanodenitrificans].	30.56	108	70	2	455	559	8	113	5e-06	58.2
rs:XP_003058690	DNA topoisomerase [Micromonas pusilla CCMP1545].	23.62	381	217	16	5	353	99	437	5e-06	60.5
tr:Q5I6D5_TRYCR	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	22.76	580	363	27	10	558	9	534	5e-06	60.1
tr:W5ACB0_WHEAT	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518};	25.27	364	230	14	47	389	285	627	5e-06	60.1
rs:XP_005391750	PREDICTED: DNA topoisomerase 3-beta-1 isoform X5 [Chinchilla lanigera].	26.75	243	143	12	273	498	279	503	5e-06	60.1
rs:XP_007513181	DNA topoisomerase I [Bathycoccus prasinos].	22.48	427	240	17	7	390	116	494	5e-06	60.1
rs:WP_019741898	topoisomerase I, partial [Pseudomonas savastanoi].	21.77	395	266	12	129	505	2	371	5e-06	60.1
rs:WP_033398064	DNA topoisomerase I [Fusobacterium russii].	21.95	524	338	20	1	504	1	473	5e-06	60.1
rs:XP_010649355	PREDICTED: DNA topoisomerase 3-alpha isoform X3 [Vitis vinifera].	21.94	556	364	20	10	534	8	524	5e-06	60.1
rs:WP_024486384	hypothetical protein, partial [Serratia fonticola].	27.24	279	176	10	69	339	72	331	5e-06	58.9
rs:WP_036909333	hypothetical protein [Prevotella timonensis].	26.22	225	140	8	114	333	29	232	5e-06	57.8
tr:F3K9K7_PSEAJ	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:EGH93869.1}; Flags: Fragment;	34.86	109	60	3	117	221	1	102	5e-06	56.2
rs:WP_033063472	DNA topoisomerase I, partial [Clostridium botulinum].	25.14	362	234	10	97	441	41	382	5e-06	59.3
rs:XP_008879533	hypothetical protein H310_13695 [Aphanomyces invadans].	22.28	588	363	21	10	553	8	545	5e-06	60.1
rs:WP_032563899	DNA topoisomerase I, partial [Bacteroides fragilis].	32.19	146	84	6	4	141	1	139	6e-06	56.6
rs:WP_022158785	DNA topoisomerase [Prevotella sp. CAG:520].	22.37	523	322	20	7	504	6	469	6e-06	60.1
rs:WP_024771719	DNA topoisomerase I [Aquimarina macrocephali].	25.53	423	256	16	106	504	76	463	6e-06	60.1
rs:WP_036825562	DNA topoisomerase I, partial [Photobacterium sanctipauli].	27.83	212	127	9	307	505	13	211	6e-06	59.7
rs:WP_008148684	hypothetical protein, partial [Parabacteroides johnsonii].	30.13	156	94	6	4	151	1	149	6e-06	56.6
rs:WP_046332923	hypothetical protein, partial [Lactobacillus kimbladii].	24.46	372	234	14	7	360	5	347	6e-06	59.7
rs:XP_010649354	PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Vitis vinifera].	21.94	556	364	20	10	534	8	524	6e-06	60.1
rs:WP_040616878	hypothetical protein, partial [Roseibium sp. TrichSKD4].	42.35	85	48	1	462	546	26	109	6e-06	58.2
rs:WP_010725465	hypothetical protein, partial [Enterococcus faecium].	34.55	110	62	5	13	118	1	104	6e-06	56.2
rs:WP_021326602	DNA topoisomerase III, partial [Photorhabdus temperata].	40.79	76	45	0	462	537	21	96	6e-06	58.5
tr:X1K9G5_9ZZZZ	SubName: Full=Marine sediment metagenome DNA, contig: S03H2_S22780 {ECO:0000313|EMBL:GAH78703.1}; Flags: Fragment;	25.42	236	133	7	7	240	6	200	6e-06	57.4
tr:W1G0B4_ECOLX	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286};	24.30	358	210	12	7	339	6	327	6e-06	58.9
rs:XP_010649353	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Vitis vinifera].	21.94	556	364	20	10	534	8	524	6e-06	60.1
rs:WP_032894880	DNA topoisomerase I [Fusobacterium hwasookii].	23.15	527	319	21	7	505	11	479	6e-06	59.7
rs:XP_814477	DNA topoisomerase III [Trypanosoma cruzi strain CL Brener].	22.76	580	363	27	10	558	9	534	6e-06	60.1
tr:W1Y7F5_9ZZZZ	SubName: Full=DNA topoisomerase {ECO:0000313|EMBL:ETJ37625.1}; Flags: Fragment;	36.11	72	44	1	481	552	1	70	6e-06	55.8
rs:WP_032844749	DNA topoisomerase I, partial [Fusobacterium nucleatum].	21.69	521	332	20	7	504	11	478	6e-06	59.7
rs:WP_005913038	DNA topoisomerase I [Fusobacterium nucleatum].	21.69	521	332	20	7	504	11	478	6e-06	59.7
rs:WP_009577130	DNA topoisomerase I, partial [gamma proteobacterium IMCC3088].	25.22	341	213	14	88	414	99	411	6e-06	59.3
rs:XP_001606777	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Nasonia vitripennis].	24.35	230	155	7	278	498	282	501	6e-06	59.7
rs:XP_006623298	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X2 [Apis dorsata].	22.14	429	279	19	97	498	101	501	6e-06	59.7
rs:XP_006623297	PREDICTED: DNA topoisomerase 3-beta-1-like isoform X1 [Apis dorsata].	22.14	429	279	19	97	498	101	501	6e-06	59.7
gp:CP003166_1147	DNA topoisomerase I [Staphylococcus aureus subsp. aureus M013]	25.00	240	140	7	7	245	8	208	7e-06	58.2
rs:WP_002354369	hypothetical protein, partial [Enterococcus faecium].	29.80	151	95	3	423	563	1	150	7e-06	57.8
tr:K8BYZ7_9ENTR	SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:CCJ97843.1}; EC=5.99.1.2 {ECO:0000313|EMBL:CCJ97843.1};	36.11	72	46	0	468	539	5	76	7e-06	56.6
rs:WP_032840878	DNA topoisomerase I [Fusobacterium sp. CM21].	21.69	521	332	20	7	504	11	478	7e-06	59.7
rs:WP_004797058	DNA topoisomerase I [Mycoplasma canis].	21.28	531	335	23	7	510	5	479	7e-06	59.3
rs:WP_033613498	DNA topoisomerase, partial [Enterococcus faecium].	25.73	206	145	4	135	339	18	216	7e-06	57.4
rs:XP_008206402	PREDICTED: DNA topoisomerase 3-beta-1 isoform X2 [Nasonia vitripennis].	24.35	230	155	7	278	498	229	448	7e-06	59.7
rs:WP_019894281	DNA topoisomerase I, partial [Lactobacillus paracasei].	30.92	207	118	10	198	390	47	242	7e-06	57.8
rs:WP_002353633	hypothetical protein, partial [Enterococcus faecium].	31.08	148	91	3	426	563	1	147	8e-06	58.2
rs:WP_000047315	DNA topoisomerase III [Bacillus cereus].	33.33	114	66	5	3	114	2	107	8e-06	55.8
rs:XP_003704123	PREDICTED: DNA topoisomerase 3-beta-1 [Megachile rotundata].	22.33	430	277	18	97	498	101	501	8e-06	59.7
rs:WP_004796196	DNA topoisomerase I [Mycoplasma canis].	21.28	531	335	23	7	510	5	479	8e-06	59.3
tr:X0PF39_9LACO	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	28.57	203	129	6	107	306	99	288	8e-06	58.5
rs:WP_002376296	topoisomerase [Enterococcus faecium].	31.19	109	71	2	108	215	1	106	8e-06	55.8
tr:C7IPE2_THEET	RecName: Full=DNA topoisomerase {ECO:0000256|SAAS:SAAS00046608}; EC=5.99.1.2 {ECO:0000256|SAAS:SAAS00046608};	25.71	315	184	11	5	313	4	274	8e-06	57.8
tr:S6PVT2_PSESF	RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU000518, ECO:0000256|SAAS:SAAS00085286}; Flags: Fragment;	22.45	392	267	11	129	505	8	377	8e-06	59.3
rs:WP_010724785	hypothetical protein, partial [Enterococcus faecium].	26.29	194	135	4	147	339	2	188	8e-06	56.6
rs:XP_002617565	hypothetical protein CLUG_03009 [Clavispora lusitaniae ATCC 42720].	23.76	463	292	20	107	547	114	537	8e-06	59.3
rs:XP_002139350	DNA topoisomerase family protein [Cryptosporidium muris RN66].	22.91	467	296	19	105	547	164	590	8e-06	59.3
rs:WP_033659061	hypothetical protein [Enterococcus faecium].	34.12	85	53	1	376	457	29	113	8e-06	56.2
rs:WP_014973869	DNA topoisomerase I [Leuconostoc carnosum].	20.73	463	295	15	7	432	6	433	9e-06	59.3
rs:WP_032881893	DNA topoisomerase I [Fusobacterium hwasookii].	23.63	529	314	23	7	505	11	479	9e-06	59.3
rs:WP_022082367	DNA topoisomerase III [Bacteroides sp. CAG:144].	28.26	138	89	3	402	531	2	137	9e-06	58.2
tr:W2FWD4_PHYPR	SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETK75057.1};	21.23	570	394	17	8	553	6	544	9e-06	59.3
rs:XP_011011407	PREDICTED: DNA topoisomerase 3-alpha-like isoform X2 [Populus euphratica].	21.99	473	309	17	97	546	101	536	9e-06	59.3
rs:WP_042229523	topoisomerase [Lactobacillus reuteri].	22.52	493	300	20	7	452	6	463	9e-06	59.3
rs:WP_002350395	hypothetical protein, partial [Enterococcus faecium].	31.08	148	91	3	426	563	1	147	9e-06	58.2
rs:WP_023250849	DNA topoisomerase I subunit omega, partial [Salmonella enterica].	25.21	357	198	14	7	334	6	322	9e-06	58.2
rs:WP_027121510	DNA topoisomerase I [Mycoplasma leonicaptivi].	22.52	444	274	15	92	504	63	467	9e-06	58.9
rs:XP_745425	DNA topoisomerase III [Plasmodium chabaudi chabaudi].	27.48	262	147	14	282	531	343	573	9e-06	59.3
rs:WP_011361129	DNA topoisomerase I [Chlorobium chlorochromatii].	22.92	624	373	27	5	588	14	569	9e-06	59.3
rs:WP_032744981	DNA topoisomerase I [Bifidobacterium longum].	22.89	367	205	14	7	336	6	331	9e-06	59.3
rs:WP_044243450	DNA topoisomerase III, partial [Pantoea stewartii].	28.57	147	92	5	8	150	6	143	1e-05	55.8
rs:WP_004794516	DNA topoisomerase I [Mycoplasma canis].	21.28	531	335	23	7	510	5	479	1e-05	58.9