PCIDB

KNApSAcK Metabolite C00007363

Metabolite

KNApSAcK Entry

id C00007363
Name delta-Tocopherol
CAS RN 119-13-1
Standard InChI InChI=1S/C27H46O2/c1-20(2)10-7-11-21(3)12-8-13-22(4)14-9-16-27(6)17-15-24-19-25(28)18-23(5)26(24)29-27/h18-22,28H,7-17H2,1-6H3/t21-,22-,27-/m1/s1
Standard InChI (Main Layer) InChI=1S/C27H46O2/c1-20(2)10-7-11-21(3)12-8-13-22(4)14-9-16-27(6)17-15-24-19-25(28)18-23(5)26(24)29-27/h18-22,28H,7-17H2,1-6H3

Cluster

Phytochemical cluster
KCF-S cluster No. 1290

Link

ChEMBL

By standard InChI CHEMBL1451395
By standard InChI Main Layer CHEMBL1451395 CHEMBL1734310

KEGG

By LinkDB C14151

CTD

By CAS RN C479072

Species

Summary

Plant class

class name count
Liliopsida 8
rosids 7
asterids 6
eudicotyledons 2
Embryophyta 2

Family (Top 10)

family name count
Poaceae 5
Apiaceae 3
Arecaceae 2
Pelliaceae 1
Hippocastanaceae 1
Amaranthaceae 1
Bixaceae 1
Calophyllaceae 1
Radulaceae 1
Brassicaceae 1

List (25)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Aesculus hippocatanum Hort. 43363 Hippocastanaceae rosids Viridiplantae
Amaranthus hypochondriacus L. 28502 Amaranthaceae eudicotyledons Viridiplantae
Arabidopsis thaliana 3702 Brassicaceae rosids Viridiplantae
Avena sativa L. 4498 Poaceae Liliopsida Viridiplantae
Bixa orellana L. 66672 Bixaceae rosids Viridiplantae
Calophyllum inophyllum L. 158927 Calophyllaceae rosids Viridiplantae
Carum carvi L. 48032 Apiaceae asterids Viridiplantae
Cocos nucifera L. 13894 Arecaceae Liliopsida Viridiplantae
Coriandrum sativum L. 4047 Apiaceae asterids Viridiplantae
Elaeis guineensis Jacq. 51953 Arecaceae Liliopsida Viridiplantae
Foeniculum vulgare L. 48037 Apiaceae asterids Viridiplantae
Gevuina avellana Mol. 54938 Proteaceae eudicotyledons Viridiplantae
Hevea brasiliensis Mull.Arg. 3980 Euphorbiaceae rosids Viridiplantae
Hordeum vulgare L. 4513 Poaceae Liliopsida Viridiplantae
Juglans regia L. 51240 Juglandaceae rosids Viridiplantae
Litchi chinensis Sonn. 151069 Sapindaceae rosids Viridiplantae
Nicotiana tabacum L. 4097 Solanaceae asterids Viridiplantae
Oryza sativa L. 4530 Poaceae Liliopsida Viridiplantae
Pellia epiphylla 40340 Pelliaceae Embryophyta Viridiplantae
Potamogeton pectinatus 55444 Potamogetonaceae Liliopsida Viridiplantae
Radula perrottetii 280841 Radulaceae Embryophyta Viridiplantae
Rosmarinus officinalis L. 39177 Lamiaceae asterids Viridiplantae
Secale cereale L. 4550 Poaceae Liliopsida Viridiplantae
Vaccinium macrocarpon Aiton 13750 Ericaceae asterids Viridiplantae
Zea mays L. 4577 Poaceae Liliopsida Viridiplantae

Human Protein / Gene in interaction

3 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P02545 Prelamin-A/C Unclassified protein CHEMBL1451395 CHEMBL1614544 (1)
11 / 10
O75496 Geminin Unclassified protein CHEMBL1734310 CHEMBL2114780 (1)
0 / 0
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL1734310 CHEMBL1737991 (1)
0 / 0

CTD interaction (1)

compound gene gene name gene description interaction interaction type form reference
pmid
C479072 1382 CRABP2
CRABP-II
RBP6
cellular retinoic acid binding protein 2 [Tretinoin co-treated with delta-tocopherol] results in increased expression of CRABP2 mRNA affects cotreatment
/ increases expression
mRNA 15225641

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545

KEGG DISEASE (10)

KEGG disease name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)