Organism name | Rhus javanica |
---|---|
Genus | Rhus |
Family | Anacardiaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Brucea javanica |
---|---|
Linked NCBI taxonomy ID | 210348 |
Linked level | species |
Family in NCBI taxonomy | Simaroubaceae |
---|---|
ID | 23808 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | rosids |
---|---|
ID | 71275 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00032984 |
Fouquierone
/ (+)-Fouquierone |
CHEMBL224814
|
No. 23 | No. 51 | ||||
C00033061 |
Isofouquierone peroxide
/ (+)-Isofouquierone peroxide |
No. 23 | No. 51 | |||||
C00006941 |
Butein
|
CHEMBL128000
|
C040918
|
17 / 31 / 34 | 8 / 0 | No. 92 | No. 13 | |
C00008026 |
Sulfuretin
/ Sulphuretin / 6,3',4'-Trihydroxyaurone |
CHEMBL490355
CHEMBL513487 |
C054989
|
42 / 37 / 34 | No. 450 | No. 13 | ||
C00033379 |
Semialatic acid
|
No. 827 |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P11473 | Vitamin D3 receptor | NR1I1 | C00006941 C00008026 | 2 / 3 |
O00255 | Menin | Unclassified protein | C00006941 C00008026 | 2 / 5 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00006941 C00008026 | 0 / 0 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00006941 C00008026 | 0 / 0 |
P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00006941 C00008026 | 0 / 0 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00006941 C00008026 | 1 / 2 |
P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00006941 | 0 / 0 |
P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00006941 | 0 / 0 |
Q9HBX9 | Relaxin receptor 1 | Relaxin receptor | C00008026 | 0 / 0 |
Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00008026 | 1 / 0 |
P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00006941 | 1 / 8 |
Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00008026 | 0 / 0 |
P47901 | Vasopressin V1b receptor | Vasopressin and oxytocin receptor | C00008026 | 0 / 0 |
P39748 | Flap endonuclease 1 | Enzyme | C00008026 | 0 / 0 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00008026 | 0 / 0 |
P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00008026 | 2 / 0 |
P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00008026 | 4 / 2 |
P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00008026 | 0 / 0 |
P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00008026 | 7 / 3 |
Q9Y253 | DNA polymerase eta | Enzyme | C00008026 | 1 / 1 |
P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00008026 | 0 / 0 |
P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00008026 | 3 / 1 |
P11308 | Transcriptional regulator ERG | Unclassified protein | C00008026 | 1 / 2 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00008026 | 0 / 0 |
Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00008026 | 0 / 0 |
P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00008026 | 1 / 1 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00008026 | 3 / 1 |
P35968 | Vascular endothelial growth factor receptor 2 | Vegfr | C00006941 | 1 / 0 |
P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00006941 | 2 / 3 |
P10696 | Alkaline phosphatase, placental-like | Enzyme | C00008026 | 0 / 1 |
P08253 | 72 kDa type IV collagenase | M10A | C00008026 | 1 / 3 |
O15118 | Niemann-Pick C1 protein | Unclassified protein | C00008026 | 1 / 1 |
Q8WXD0 | Relaxin receptor 2 | Relaxin receptor | C00008026 | 1 / 1 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00008026 | 0 / 0 |
P11362 | Fibroblast growth factor receptor 1 | Fgfr | C00006941 | 4 / 5 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00008026 | 0 / 0 |
P04062 | Glucosylceramidase | Enzyme | C00006941 | 6 / 4 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00008026 | 4 / 3 |
P10721 | Mast/stem cell growth factor receptor Kit | Pdgfr | C00006941 | 4 / 3 |
P21802 | Fibroblast growth factor receptor 2 | TK tyrosine-protein kinase TLK subfamily | C00006941 | 9 / 3 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00008026 | 0 / 0 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00008026 | 0 / 0 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00008026 | 0 / 0 |
Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00008026 | 0 / 0 |
O00487 | 26S proteasome non-ATPase regulatory subunit 14 | Enzyme | C00008026 | 0 / 0 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00008026 | 0 / 0 |
Q13951 | Core-binding factor subunit beta | Unclassified protein | C00008026 | 0 / 1 |
Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00008026 | 1 / 4 |
P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00006941 | 0 / 0 |
P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00006941 | 0 / 3 |
O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00008026 | 0 / 0 |
Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00008026 | 0 / 0 |
Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00008026 | 2 / 1 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00006941
|
1734 | DIO2, 5DII, D2, DIOII, SelY, TXDI2 | deiodinase, iodothyronine, type II (EC:1.97.1.10) |
C00006941
|
4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00006941
|
4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00006941
|
5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00006941
|
23411 | SIRT1, SIR2L1 | sirtuin 1 |
C00006941
|
7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00006941
|
7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00006941
|
OMIM | preferred title | UniProt |
---|---|---|
#219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
#207410 | Antley-bixler syndrome without genital anomalies or disordered steroidogenesis; abs2 |
P21802
|
#101200 | Apert syndrome |
P21802
|
#123790 | Beare-stevenson cutis gyrata syndrome; bstvs |
P21802
|
#614592 | Bent bone dysplasia syndrome; bbds |
P21802
|
#114480 | Breast cancer |
P38398
|
#604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
#114500 | Colorectal cancer; crc |
P84022
Q14191 |
#123500 | Crouzon syndrome |
P21802
|
#219050 | Cryptorchidism, unilateral or bilateral |
Q8WXD0
|
#612219 | Ewing sarcoma; es |
P11308
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#606764 | Gastrointestinal stromal tumor; gist |
P10721
|
#608013 | Gaucher disease, perinatal lethal |
P04062
|
#230800 | Gaucher disease, type i |
P04062
|
#230900 | Gaucher disease, type ii |
P04062
|
#231000 | Gaucher disease, type iii |
P04062
|
#231005 | Gaucher disease, type iiic |
P04062
|
#232300 | Glycogen storage disease ii |
P10253
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#602089 | Hemangioma, capillary infantile |
P35968
|
#114550 | Hepatocellular carcinoma |
P08581
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#147950 | Hypogonadotropic hypogonadism 2 with or without anosmia; hh2 |
P11362
|
#146300 | Hypophosphatasia, adult |
P05186
|
#241510 | Hypophosphatasia, childhood |
P05186
|
#241500 | Hypophosphatasia, infantile |
P05186
|
#123150 | Jackson-weiss syndrome; jws |
P21802
|
#149730 | Lacrimoauriculodentodigital syndrome; ladd |
P21802
|
#601626 | Leukemia, acute myeloid; aml |
P10721
|
#613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
#211980 | Lung cancer |
P00533
|
#174800 | Mccune-albright syndrome; mas |
P63092
|
#259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
#160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
#257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
#166350 | Osseous heteroplasia, progressive; poh |
P63092
|
#166250 | Osteoglophonic dysplasia; ogd |
P11362
|
#167000 | Ovarian cancer |
P38398
|
#614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
#168600 | Parkinson disease, late-onset; pd |
P04062
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#101600 | Pfeiffer syndrome |
P11362
P21802 |
#172700 | Pick disease of brain |
P10636
|
#172800 | Piebald trait; pbt |
P10721
|
#102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
#601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
#103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
#603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
#612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
#605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
#609579 | Scaphocephaly, maxillary retrusion, and mental retardation |
P21802
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#273300 | Testicular germ cell tumor; tgct |
P10721
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
#190440 | Trigonocephaly 1; trigno1 |
P11362
|
#277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
#277700 | Werner syndrome; wrn |
Q14191
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
|
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
H00018 | Gastric cancer |
P00533
(related)
P08581 (related) P21802 (related) |
H00022 | Bladder cancer |
P00533
(related)
|
H00028 | Choriocarcinoma |
P00533
(related)
P08253 (related) |
H00030 | Cervical cancer |
P00533
(related)
|
H00042 | Glioma |
P00533
(related)
P00533 (marker) |
H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
H00126 | Gaucher disease |
P04062
(related)
|
H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
H00213 | Hypophosphatasia |
P05186
(related)
|
H00025 | Penile cancer |
P08253
(related)
P35354 (related) |
H00472 | Torg-Winchester syndrome |
P08253
(related)
|
H00021 | Renal cell carcinoma |
P08581
(related)
|
H00046 | Cholangiocarcinoma |
P08581
(related)
P35354 (related) |
H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00023 | Testicular cancer |
P10696
(marker)
P10721 (marker) |
H00003 | Acute myeloid leukemia (AML) |
P10721
(related)
P10721 (marker) Q01196 (related) Q01196 (marker) Q13951 (marker) |
H00170 | Piebaldism |
P10721
(related)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H00024 | Prostate cancer |
P11308
(related)
|
H00035 | Ewing's sarcoma |
P11308
(related)
|
H00255 | Hypogonadotropic hypogonadism |
P11362
(related)
|
H00443 | Osteoglophonic dysplasia (OD) |
P11362
(related)
|
H00458 | Craniosynostosis |
P11362
(related)
P21802 (related) |
H00516 | Isolated orofacial clefts |
P11362
(related)
|
H01207 | Trigonocephaly |
P11362
(related)
|
H00342 | Tuberculosis |
P11473
(related)
|
H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
H00642 | Lacrimo-auriculo-dento-digital syndrome (LADD) |
P21802
(related)
|
H00027 | Ovarian cancer |
P38398
(related)
|
H00031 | Breast cancer |
P38398
(related)
|
H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00296 | Defects in RecQ helicases |
Q14191
(related)
|
H00609 | 46,XY disorders of sex development (Other) |
Q8WXD0
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|