Species

KNApSAcK Entry

Organism name Illicium angustisepalum
Genus Illicium
Family Illiciaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Illicium angustisepalum
Linked NCBI taxonomy ID 124793
Linked level species

Family

Family in NCBI taxonomy Schisandraceae
ID 16733

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (13)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00049953 External link 512 4-epi-Sandaracopimaric acid
/ (+)-4-epi-Sandaracopimaric acid
CHEMBL513197
CHEMBL1397211
CHEMBL1410398
CHEMBL1735595
14 / 13 / 7 No. 208 No. 48
C00049989 External link 512 Angustanoic acid E
No. 323 No. 41
C00049984 External link 512 Angustanoic acid F
CHEMBL598566
CHEMBL1348397
6 / 8 / 4 No. 323 No. 41
C00049990 External link 512 Angustanoic acid G
/ (+)-Angustanoic acid G
No. 323 No. 41
C00049993 External link 512 Angustanol
/ (+)-Angustanol
CHEMBL601734
No. 1937
C00040871 External link 512 Angustisepalin
/ (-)-Angustisepalin
No. 2313
C00049986 External link 512 Angustanoic acid B
/ (-)-Angustanoic acid B
No. 2917
C00049988 External link 512 Angustanoic acid D
/ (-)-Angustanoic acid D
No. 2917
C00049991 External link 512 Angustanoic acid H
No. 2917
C00049987 External link 512 Angustanoic acid C
/ (+)-Angustanoic acid C
No. 2917
C00049992 External link 512 Angustanoic acid I
/ (+)-Angustanoic acid I
No. 3448
C00049985 External link 512 Angustanoic acid A
/ (+)-Angustanoic acid A
No. 4470
C00049983 External link 512 Angustanal
/ (+)-Angustanal
No. 4470

Human Protein / Gene in interactions

18 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00049953 C00049984 7 / 3
Q9Y253 DNA polymerase eta Enzyme C00049953 C00049984 1 / 1
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00049984 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00049953 0 / 1
P47870 Gamma-aminobutyric acid receptor subunit beta-2 GABA-A beta C00049953 0 / 0
P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABA-A alpha C00049953 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00049953 2 / 0
O75496 Geminin Unclassified protein C00049953 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00049953 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00049953 0 / 0
P06746 DNA polymerase beta Enzyme C00049984 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00049953 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00049953 1 / 1
Q9UNA4 DNA polymerase iota Enzyme C00049984 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00049953 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00049984 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00049953 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00049953 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#114500 Colorectal cancer; crc P84022
#609535 Drug metabolism, poor, cyp2c19-related P33261
#611136 Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 P14867
#137800 Glioma susceptibility 1; glm1 O75874
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (7)

KEGG name UniProt
H01205 Coumarin resistance P11712 (related)
H00808 Idiopathic generalized epilepsies (IGEs) P14867 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)