Species

KNApSAcK Entry

Organism name Musa sapientum
Genus Musa
Family Musaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Musa x paradisiaca
Linked NCBI taxonomy ID 89151
Linked level species

Family

Family in NCBI taxonomy Musaceae
ID 4637

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001426 External link 512 Phenethylamine
CHEMBL610
C029261
8 / 6 / 2 6 / 5 No. 885
C00001408 External link 512 Dopamine
CHEMBL59
D004298
69 / 40 / 56 51 / 52 No. 1114 No. 6
C00001429 External link 512 Serotonin
/ Enteramin
/ Enteramine
/ DS substance
/ Thrombotonin
/ Thrombocytin
/ 5-Hydroxytryptamine
CHEMBL39
CHEMBL1628597
D012701
78 / 35 / 22 32 / 40 No. 1910 No. 4
C00001424 External link 512 Norepinephrine
/ L-Noradrenaline
/ (-)-Norepinephrine
CHEMBL432
CHEMBL18824
CHEMBL1437
CHEMBL2311152
D009638
50 / 33 / 35 36 / 90 No. 3197
C00001414 External link 512 Histamine
CHEMBL90
D006632
30 / 21 / 20 63 / 40 No. 4250

Human Protein / Gene in interactions

151 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001408 C00001414 C00001424 C00001429 0 / 1
O15244 Solute carrier family 22 member 2 Drug uniporter C00001408 C00001414 C00001424 C00001429 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001408 C00001414 C00001424 C00001429 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001408 C00001414 C00001429 1 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00001408 C00001414 C00001429 0 / 0
O75751 Solute carrier family 22 member 3 Unclassified protein C00001414 C00001424 C00001429 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00001408 C00001424 C00001429 0 / 0
P23280 Carbonic anhydrase 6 Lyase C00001408 C00001414 C00001429 0 / 0
P14416 D(2) dopamine receptor Dopamine receptor C00001408 C00001424 C00001429 2 / 0
P00915 Carbonic anhydrase 1 Lyase C00001408 C00001414 C00001429 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00001408 C00001414 C00001429 1 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001408 C00001414 C00001429 0 / 1
P07451 Carbonic anhydrase 3 Lyase C00001408 C00001414 C00001429 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00001408 C00001424 C00001429 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001408 C00001414 C00001429 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00001408 C00001414 C00001429 0 / 1
O43570 Carbonic anhydrase 12 Lyase C00001408 C00001414 C00001429 1 / 2
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001408 C00001414 C00001429 1 / 1
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00001408 C00001414 C00001429 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00001408 C00001414 C00001429 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00001408 C00001414 C00001429 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00001408 C00001414 C00001429 1 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00001408 C00001424 0 / 1
O15245 Solute carrier family 22 member 1 Drug uniporter C00001408 C00001414 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00001408 C00001429 5 / 1
P02545 Prelamin-A/C Unclassified protein C00001414 C00001424 11 / 10
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001408 C00001424 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00001408 C00001414 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00001414 C00001429 3 / 2
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00001408 C00001429 3 / 0
P49286 Melatonin receptor type 1B Melatonin receptor C00001408 C00001429 0 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00001408 C00001424 4 / 3
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00001408 C00001424 1 / 1
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00001426 C00001429 0 / 0
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00001408 C00001424 1 / 0
Q16853 Membrane primary amine oxidase Enzyme C00001408 C00001426 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00001408 C00001424 0 / 0
P35368 Alpha-1B adrenergic receptor Adrenergic receptor C00001408 C00001424 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00001408 C00001424 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00001408 C00001424 0 / 0
P48039 Melatonin receptor type 1A Melatonin receptor C00001408 C00001429 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00001408 C00001429 2 / 0
P14679 Tyrosinase Oxidoreductase C00001408 C00001429 4 / 2
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00001414 C00001424 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00001414 C00001429 2 / 0
P16662 UDP-glucuronosyltransferase 2B7 Enzyme C00001408 C00001429 0 / 0
P50224 Sulfotransferase 1A3/1A4 Enzyme C00001408 C00001424 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00001424 C00001426 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00001408 C00001424 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00001408 C00001429 1 / 0
P35348 Alpha-1A adrenergic receptor Adrenergic receptor C00001408 C00001424 0 / 0
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00001408 C00001424 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00001408 C00001424 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001408 C00001424 0 / 0
P54855 UDP-glucuronosyltransferase 2B15 Enzyme C00001408 C00001429 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00001424 C00001429 0 / 0
P39748 Flap endonuclease 1 Enzyme C00001408 C00001424 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00001408 C00001424 1 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001408 C00001424 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00001408 0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00001426 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00001408 0 / 0
O15296 Arachidonate 15-lipoxygenase B Enzyme C00001424 0 / 0
P28566 5-hydroxytryptamine receptor 1E Serotonin receptor C00001429 0 / 0
P50225 Sulfotransferase 1A1 Enzyme C00001408 0 / 0
P05164 Myeloperoxidase Enzyme C00001429 1 / 2
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00001429 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00001408 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00001424 2 / 3
Q9HAW7 UDP-glucuronosyltransferase 1-7 Enzyme C00001408 0 / 0
P46098 5-hydroxytryptamine receptor 3A NS C00001429 0 / 0
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00001429 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00001424 1 / 0
Q9H3N8 Histamine H4 receptor Histamine receptor C00001414 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00001424 0 / 0
Q9GZT4 Serine racemase Enzyme C00001424 0 / 0
P54132 Bloom syndrome protein Enzyme C00001424 1 / 2
P14920 D-amino-acid oxidase Enzyme C00001424 0 / 0
O95622 Adenylate cyclase type 5 Enzyme C00001408 1 / 0
P06241 Tyrosine-protein kinase Fyn Src C00001408 0 / 0
P08183 Multidrug resistance protein 1 drug C00001426 1 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00001429 0 / 0
P36544 Neuronal acetylcholine receptor subunit alpha-7 CHRN alpha C00001429 0 / 0
P47898 5-hydroxytryptamine receptor 5A Serotonin receptor C00001429 0 / 0
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00001429 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00001424 0 / 0
P21918 D(1B) dopamine receptor Dopamine receptor C00001408 1 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00001408 1 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00001408 3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00001424 2 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001424 0 / 0
P06133 UDP-glucuronosyltransferase 2B4 Enzyme C00001429 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00001414 0 / 0
P22303 Acetylcholinesterase Hydrolase C00001429 1 / 0
P28222 5-hydroxytryptamine receptor 1B Serotonin receptor C00001429 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00001429 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00001424 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00001408 0 / 0
P25021 Histamine H2 receptor Histamine receptor C00001414 0 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00001424 3 / 1
P23415 Glycine receptor subunit alpha-1 GLR alpha C00001429 1 / 1
Q96RJ0 Trace amine-associated receptor 1 Trace amine receptor C00001426 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00001424 0 / 0
O43704 Sulfotransferase family cytosolic 1B member 1 Enzyme C00001408 0 / 0
Q99489 D-aspartate oxidase Enzyme C00001424 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001424 0 / 0
Q99549 M-phase phosphoprotein 8 Unclassified protein C00001408 0 / 0
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00001429 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001424 0 / 0
P07477 Trypsin-1 S1A C00001426 1 / 1
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00001429 1 / 0
Q9Y5N1 Histamine H3 receptor Histamine receptor C00001414 0 / 0
P33765 Adenosine receptor A3 Adenosine receptor C00001429 0 / 0
Q13639 5-hydroxytryptamine receptor 4 Serotonin receptor C00001429 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00001429 0 / 3
P30939 5-hydroxytryptamine receptor 1F Serotonin receptor C00001429 0 / 0
Q7Z2W7 Transient receptor potential cation channel subfamily M member 8 Unclassified protein C00001429 0 / 0
Q99700 Ataxin-2 Unclassified protein C00001408 1 / 1
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00001408 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00001414 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00001426 4 / 1
P40225 Thrombopoietin Unclassified protein C00001408 1 / 1
O75795 UDP-glucuronosyltransferase 2B17 Enzyme C00001429 1 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00001408 7 / 37
O00255 Menin Unclassified protein C00001424 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001424 1 / 2
Q13951 Core-binding factor subunit beta Unclassified protein C00001424 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00001424 1 / 4
Q9UN88 Gamma-aminobutyric acid receptor subunit theta GABA-A theta C00001429 0 / 0
P28472 Gamma-aminobutyric acid receptor subunit beta-3 GABA-A beta C00001429 1 / 0
P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABA-A alpha C00001429 1 / 1
P48169 Gamma-aminobutyric acid receptor subunit alpha-4 GABA-A alpha C00001429 0 / 0
O14764 Gamma-aminobutyric acid receptor subunit delta GABA-A delta C00001429 1 / 1
P31644 Gamma-aminobutyric acid receptor subunit alpha-5 GABA-A alpha C00001429 0 / 0
Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 GABA-A gamma C00001429 0 / 0
P78334 Gamma-aminobutyric acid receptor subunit epsilon GABA-A epsilon C00001429 0 / 0
Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 GABA-A gamma C00001429 0 / 0
P34903 Gamma-aminobutyric acid receptor subunit alpha-3 GABA-A alpha C00001429 0 / 0
O00591 Gamma-aminobutyric acid receptor subunit pi GABA-A pi C00001429 0 / 0
P47870 Gamma-aminobutyric acid receptor subunit beta-2 GABA-A beta C00001429 0 / 0
P18507 Gamma-aminobutyric acid receptor subunit gamma-2 GABA-A gamma C00001429 4 / 2
P18505 Gamma-aminobutyric acid receptor subunit beta-1 GABA-A beta C00001429 0 / 0
Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 GABA-A alpha C00001429 0 / 0
P47869 Gamma-aminobutyric acid receptor subunit alpha-2 GABA-A alpha C00001429 1 / 0
Q9Y2I1 Nischarin Other cytosolic protein C00001424 0 / 0
Q8WXA8 5-hydroxytryptamine receptor 3C NS C00001429 0 / 0
Q70Z44 5-hydroxytryptamine receptor 3D NS C00001429 0 / 0
O95264 5-hydroxytryptamine receptor 3B NS C00001429 0 / 0
A5X5Y0 5-hydroxytryptamine receptor 3E NS C00001429 0 / 0
P42345 Serine/threonine-protein kinase mTOR Enzyme C00001408 0 / 0
P28221 5-hydroxytryptamine receptor 1D Serotonin receptor C00001429 0 / 0

140 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
6570 SLC18A1, CGAT, VAT1, VMAT1 solute carrier family 18 (vesicular monoamine transporter), member 1 C00001408 C00001414 C00001424 C00001426
C00001429
6531 SLC6A3, DAT, DAT1, PKDYS solute carrier family 6 (neurotransmitter transporter), member 3 C00001408 C00001424 C00001426 C00001429
6530 SLC6A2, NAT1, NET, NET1, SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 2 C00001408 C00001424 C00001426 C00001429
6571 SLC18A2, SVAT, SVMT, VAT2, VMAT2 solute carrier family 18 (vesicular monoamine transporter), member 2 C00001408 C00001414 C00001424 C00001429
6532 SLC6A4, 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT solute carrier family 6 (neurotransmitter transporter), member 4 C00001408 C00001424 C00001426 C00001429
134864 TAAR1, RP11-295F4.9, TA1, TAR1, TRAR1 trace amine associated receptor 1 C00001408 C00001424 C00001426 C00001429
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00001408 C00001414 C00001424
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00001408 C00001414 C00001424
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00001414 C00001424 C00001429
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00001414 C00001424 C00001429
6818 SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) C00001408 C00001424 C00001429
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00001408 C00001414 C00001429
1312 COMT catechol-O-methyltransferase (EC:2.1.1.6) C00001408 C00001424
847 CAT catalase (EC:1.11.1.6) C00001408 C00001429
840 CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) C00001408 C00001424
154 ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR adrenoceptor beta 2, surface C00001414 C00001424
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00001408 C00001424
3593 IL12B, CLMF, CLMF2, IL-12B, NKSF, NKSF2 interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) C00001414 C00001429
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00001408 C00001429
1813 DRD2, D2DR, D2R dopamine receptor D2 C00001408 C00001424
2152 F3, CD142, TF, TFA coagulation factor III (thromboplastin, tissue factor) C00001408 C00001414
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00001408 C00001414
85413 SLC22A16, CT2, FLIPT2, OAT6, OCT6, OKB1, dJ261K5.1 solute carrier family 22 (organic cation/carnitine transporter), member 16 C00001408 C00001429
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00001414 C00001424
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00001408 C00001429
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00001414 C00001424
4128 MAOA, MAO-A monoamine oxidase A (EC:1.4.3.4) C00001424 C00001429
9177 HTR3B, 5-HT3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic C00001408 C00001429
3359 HTR3A, 5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic C00001408 C00001429
6863 TAC1, Hs.2563, NK2, NKNA, NPK, TAC2 tachykinin, precursor 1 C00001414
3630 INS, IDDM2, ILPR, IRDN, MODY10 insulin C00001408
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00001408
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00001408
2950 GSTP1, DFN7, FAEES3, GST3, GSTP, PI glutathione S-transferase pi 1 (EC:2.5.1.18) C00001408
4137 MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU microtubule-associated protein tau C00001408
2475 MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1 mechanistic target of rapamycin (serine/threonine kinase) (EC:2.7.11.1) C00001408
4548 MTR, HMAG, MS, cblG 5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13) C00001408
5071 PARK2, AR-JP, LPRS2, PDJ, PRKN parkin RBR E3 ubiquitin protein ligase C00001408
2944 GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 glutathione S-transferase mu 1 (EC:2.5.1.18) C00001408
5617 PRL prolactin C00001408
5998 RGS3, C2PA, RGP3 regulator of G-protein signaling 3 C00001408
6198 RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1) C00001408
6343 SCT secretin C00001408
2938 GSTA1, GST2, GSTA1-1, GTH1 glutathione S-transferase alpha 1 (EC:2.5.1.18) C00001408
2668 GDNF, ATF1, ATF2, HFB1-GDNF, HSCR3 glial cell derived neurotrophic factor C00001408
9016 SLC25A14, BMCP1, UCP5 solute carrier family 25 (mitochondrial carrier, brain), member 14 C00001408
6622 SNCA, NACP, PARK1, PARK4, PD1 synuclein, alpha (non A4 component of amyloid precursor) C00001408
1812 DRD1, DADR, DRD1A dopamine receptor D1 C00001408
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00001408
7054 TH, DYT14, DYT5b, TYH tyrosine hydroxylase (EC:1.14.16.2) C00001408
1565 CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) C00001408
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00001408
25 ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2) C00001414
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001408
240 ALOX5, 5-LO, 5-LOX, 5LPG, LOG5 arachidonate 5-lipoxygenase (EC:1.13.11.34) C00001414
241 ALOX5AP, FLAP arachidonate 5-lipoxygenase-activating protein C00001414
26 AOC1, ABP, ABP1, DAO, DAO1, KAO amine oxidase, copper containing 1 (EC:1.4.3.22) C00001414
362 AQP5, AQP-5, PPKB aquaporin 5 C00001414
613 BCR, ALL, BCR1, CML, D22S11, D22S662, PHL breakpoint cluster region (EC:2.7.11.1) C00001414
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00001414
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00001414
929 CD14 CD14 molecule C00001414
958 CD40, Bp50, CDW40, TNFRSF5, p50 CD40 molecule, TNF receptor superfamily member 5 C00001414
941 CD80, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7 CD80 molecule C00001414
1017 CDK2, p33(CDK2) cyclin-dependent kinase 2 (EC:2.7.11.22) C00001414
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00001414
1027 CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 cyclin-dependent kinase inhibitor 1B (p27, Kip1) C00001414
1179 CLCA1, CACC, CACC1, CLCRG1, CaCC-1, GOB5, hCLCA1, hCaCC-1 chloride channel accessory 1 C00001414
1437 CSF2, GMCSF colony stimulating factor 2 (granulocyte-macrophage) C00001414
1906 EDN1, ET1, HDLCQ7, PPET1 endothelin 1 C00001414
1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA epidermal growth factor receptor (EC:2.7.10.1) C00001414
2205 FCER1A, FCE1A, FcERI Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide C00001414
2990 GUSB, BG, MPS7 glucuronidase, beta (EC:3.2.1.31) C00001414
3067 HDC histidine decarboxylase (EC:4.1.1.22) C00001414
3176 HNMT, HMT, HNMT-S1, HNMT-S2 histamine N-methyltransferase (EC:2.1.1.8) C00001414
3269 HRH1, H1-R, hisH1 histamine receptor H1 C00001414
3274 HRH2, H2R histamine receptor H2 C00001414
11255 HRH3, GPCR97, HH3R histamine receptor H3 C00001414
59340 HRH4, AXOR35, BG26, GPCR105, GPRv53, H4, H4R, HH4R histamine receptor H4 C00001414
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00001414
3458 IFNG, IFG, IFI interferon, gamma C00001414
3586 IL10, CSIF, GVHDS, IL-10, IL10A, TGIF interleukin 10 C00001414
3592 IL12A, CLMF, IL-12A, NFSK, NKSF1, P35 interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) C00001414
664 BNIP3, NIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 C00001408
3603 IL16, LCF, NIL16, PRIL16, prIL-16 interleukin 16 C00001414
3606 IL18, IGIF, IL-18, IL-1g, IL1F4 interleukin 18 (interferon-gamma-inducing factor) C00001414
3567 IL5, EDF, IL-5, TRF interleukin 5 (colony-stimulating factor, eosinophil) C00001414
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00001408
27113 BBC3, JFY-1, JFY1, PUMA BCL2 binding component 3 C00001408
3785 KCNQ2, BFNC, BFNS1, EBN, EBN1, EIEE7, ENB1, HNSPC, KCNA11, KV7.2, KVEBN1 potassium voltage-gated channel, KQT-like subfamily, member 2 C00001414
3786 KCNQ3, BFNC2, EBN2, KV7.3 potassium voltage-gated channel, KQT-like subfamily, member 3 C00001414
4056 LTC4S leukotriene C4 synthase (EC:4.4.1.20) C00001414
4312 MMP1, CLG, CLGN matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) C00001414
4586 MUC5AC, MUC5, TBM, leB mucin 5AC, oligomeric mucus/gel-forming C00001414
581 BAX, BCL2L4 BCL2-associated X protein C00001408
4843 NOS2, HEP-NOS, INOS, NOS, NOS2A nitric oxide synthase 2, inducible (EC:1.14.13.39) C00001414
5142 PDE4B, DPDE4, PDE4B5, PDEIVB phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17) C00001414
5321 PLA2G4A, PLA2G4, cPLA2-alpha phospholipase A2, group IVA (cytosolic, calcium-dependent) (EC:3.1.1.5 3.1.1.4) C00001414
5562 PRKAA1, AMPK, AMPKa1 protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31) C00001414
5563 PRKAA2, AMPK, AMPK2, AMPKa2, PRKAA protein kinase, AMP-activated, alpha 2 catalytic subunit (EC:2.7.11.1 2.7.11.27 2.7.11.31) C00001414
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00001414
5788 PTPRC, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200 protein tyrosine phosphatase, receptor type, C (EC:3.1.3.48) C00001414
183 AGT, ANHU, SERPINA8 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) C00001408
6581 SLC22A3, EMT, EMTH, OCT3 solute carrier family 22 (organic cation transporter), member 3 C00001414
6794 STK11, LKB1, PJS, hLKB1 serine/threonine kinase 11 (EC:2.7.11.1) C00001414
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00001408
7097 TLR2, CD282, TIL4 toll-like receptor 2 C00001414
7351 UCP2, BMIQ4, SLC25A8, UCPH uncoupling protein 2 (mitochondrial, proton carrier) C00001414
148 ADRA1A, ADRA1C, ADRA1L1, ALPHA1AAR adrenoceptor alpha 1A C00001424
147 ADRA1B, ADRA1, ALPHA1BAR adrenoceptor alpha 1B C00001424
146 ADRA1D, ADRA1, ADRA1A, ADRA1R, ALPHA1, DAR, dJ779E11.2 adrenoceptor alpha 1D C00001424
150 ADRA2A, ADRA2, ADRA2R, ADRAR, ALPHA2AAR, ZNF32 adrenoceptor alpha 2A C00001424
151 ADRA2B, ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, alpha-2BAR adrenoceptor alpha 2B C00001424
152 ADRA2C, ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR adrenoceptor alpha 2C C00001424
153 ADRB1, ADRB1R, B1AR, BETA1AR, RHR adrenoceptor beta 1 C00001424
155 ADRB3, BETA3AR adrenoceptor beta 3 C00001424
6352 CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP chemokine (C-C motif) ligand 5 C00001424
2335 FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF fibronectin 1 C00001424
2778 GNAS, AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, PHP1A, PHP1B, PHP1C, POH GNAS complex locus C00001424
4129 MAOB monoamine oxidase B (EC:1.4.3.4) C00001426
4879 NPPB, BNP natriuretic peptide B C00001424
4852 NPY, PYY4 neuropeptide Y C00001424
6279 S100A8, 60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MIF, MRP8, NIF, P8 S100 calcium binding protein A8 C00001424
6280 S100A9, 60B8AG, CAGB, CFAG, CGLB, L1AG, LIAG, MAC387, MIF, MRP14, NIF, P14 S100 calcium binding protein A9 C00001424
6285 S100B, NEF, S100, S100-B, S100beta S100 calcium binding protein B C00001424
7391 USF1, FCHL, FCHL1, HYPLIP1, MLTF, MLTFI, UEF, bHLHb11 upstream transcription factor 1 C00001424
1080 CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) C00001429
2597 GAPDH, G3PD, GAPD glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) C00001429
2932 GSK3B glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) C00001429
3352 HTR1D, 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled C00001429
3356 HTR2A, 5-HT2A, HTR2 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled C00001429
3363 HTR7, 5-HT7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled C00001429
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00001429
3690 ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) C00001429
4353 MPO myeloperoxidase (EC:1.11.2.2) C00001429
6814 STXBP3, MUNC18-3, MUNC18C, PSP, UNC-18C syntaxin binding protein 3 C00001429
7166 TPH1, TPRH, TRPH, TPH tryptophan hydroxylase 1 (EC:1.14.16.4) C00001429
8989 TRPA1, ANKTM1, FEPS transient receptor potential cation channel, subfamily A, member 1 C00001429
54578 UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) C00001429
7498 XDH, XO, XOR xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2) C00001429

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (87)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#103780 Alcohol dependence P14416
P31645
P47869
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#606798 Blepharospasm, benign essential P21918
#210900 Bloom syndrome; blm P54132
#612560 Bone mineral density quantitative trait locus 12; bmnd12 O75795
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#119900 Digital clubbing, isolated congenital P15428
#607208 Dravet syndrome P18507
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#606703 Dyskinesia, familial, with facial myokymia; fdfm O95622
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#607681 Epilepsy, childhood absence, susceptibility to, 2; eca2 P18507
#612269 Epilepsy, childhood absence, susceptibility to, 5; eca5 P28472
#613060 Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 O14764
#611136 Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 P14867
#133239 Esophageal cancer P04637
#600274 Frontotemporal dementia; ftd P10636
#604233 Generalized epilepsy with febrile seizures plus, type 1; gefsp1 P18507
#611277 Generalized epilepsy with febrile seizures plus, type 3; gefsp3 P18507
#143500 Gilbert syndrome P22309
P22310
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#149400 Hyperekplexia, hereditary 1; hkpx1 P23415
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#612244 Inflammatory bowel disease 13; ibd13 P08183
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#211980 Lung cancer P04637
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#254600 Myeloperoxidase deficiency; mpod P05164
#159900 Myoclonic dystonia P14416
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167800 Pancreatitis, hereditary; pctt P07477
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#614674 Periodic fever, menstrual cycle-dependent P08908
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#600852 Retinitis pigmentosa 17; rp17 P22748
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#187950 Thrombocythemia 1; thcyt1 P40225
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#112100 Yt blood group antigen P22303

KEGG DISEASE (90)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00783 Febrile seizures O14764 (related)
P18507 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
P35354 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00101 Other phagocyte defects P05164 (related)
H00003 Acute myeloid leukemia (AML) P05164 (marker)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00933 Hereditary pancreatitis P07477 (related)
H00079 Asthma P07550 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00808 Idiopathic generalized epilepsies (IGEs) P14867 (related)
P18507 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00208 Hyperbilirubinemia P22309 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00769 Hyperekplexia P23415 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00227 Congenital amegakaryocytic thrombocytopenia (CAMT) P40225 (marker)
H00409 Type II diabetes mellitus P49286 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)

Diseases related to CTD interactions

164 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D002375 Catalepsy C00001426
C00001408
C00001424
C00001429
D006930 Hyperalgesia C00001408
C00001414
C00001424
C00001429
D012640 Seizures C00001408
C00001414
C00001424
C00001429
D007022 Hypotension C00001408
C00001414
C00001424
C00001429
D010146 Pain C00001414
C00001424
C00001429
D009336 Necrosis C00001408
C00001424
C00001429
D013610 Tachycardia C00001408
C00001424
C00001429
D001145 Arrhythmias, Cardiac C00001408
C00001414
C00001424
D013226 Status Epilepticus C00001408
C00001424
C00001429
D004409 Dyskinesia, Drug-Induced C00001426
C00001408
C00001424
D002389 Catatonia C00001408
C00001414
C00001429
D006973 Hypertension C00001408
C00001424
C00001429
D012772 Shock, Septic C00001408
C00001414
C00001424
D004342 Drug Hypersensitivity C00001408
C00001414
D013276 Stomach Ulcer C00001414
C00001429
D004417 Dyspnea C00001408
C00001414
D004802 Eosinophilia C00001408
C00001414
D006323 Heart Arrest C00001408
C00001424
D006331 Heart Diseases C00001408
C00001424
D006333 Heart Failure C00001408
C00001424
D012771 Shock, Hemorrhagic C00001414
C00001424
D019970 Cocaine-Related Disorders C00001408
C00001424
D001008 Anxiety Disorders C00001424
C00001429
D002303 Cardiac Output, Low C00001408
C00001424
D011537 Pruritus C00001414
C00001429
D001321 Autistic Disorder C00001424
C00001429
D007024 Hypotension, Orthostatic C00001408
C00001424
D001919 Bradycardia C00001424
C00001429
D009203 Myocardial Infarction C00001414
C00001424
D009135 Muscular Diseases C00001414
C00001429
D006261 Headache C00001414
C00001424
D017202 Myocardial Ischemia C00001408
C00001424
D018487 Ventricular Dysfunction, Left C00001408
C00001424
D058186 Acute Kidney Injury C00001408
C00001424
D009410 Nerve Degeneration C00001408
C00001424
D009422 Nervous System Diseases C00001408
C00001429
D009846 Oliguria C00001408
C00001424
D014202 Tremor C00001408
C00001429
D013616 Tachycardia, Sinus C00001408
C00001424
D006976 Hypertension, Pulmonary C00001424
C00001429
D013375 Substance Withdrawal Syndrome C00001408
C00001424
D017379 Hypertrophy, Left Ventricular C00001424
C00001429
D006948 Hyperkinesis C00001426
C00001408
D012769 Shock C00001408
C00001424
D012770 Shock, Cardiogenic C00001408
C00001424
D007008 Hypokalemia C00001408
C00001424
D010554 Personality Disorders C00001424
D011595 Psychomotor Agitation C00001408
D010547 Persistent Fetal Circulation Syndrome C00001408
D020734 Parkinsonian Disorders C00001408
D016171 Torsades de Pointes C00001408
D010300 Parkinson Disease C00001408
D020301 Vasospasm, Intracranial C00001408
D009205 Myocarditis C00001408
D000799 Angioedema C00001414
D001249 Asthma C00001414
D055963 Asthma, Aspirin-Induced C00001414
D001862 Bone Resorption C00001414
D001986 Bronchial Spasm C00001414
D003233 Conjunctivitis, Allergic C00001414
D003329 Coronary Vasospasm C00001414
D056486 Drug-Induced Liver Injury C00001414
D004890 Erythema C00001414
D048629 Micronuclei, Chromosome-Defective C00001408
D006967 Hypersensitivity C00001414
D006968 Hypersensitivity, Delayed C00001414
D006969 Hypersensitivity, Immediate C00001414
D006975 Hypertension, Portal C00001414
D007410 Intestinal Diseases C00001414
D034701 Mastocytosis, Cutaneous C00001414
D008545 Melanoma C00001414
D008569 Memory Disorders C00001414
D008881 Migraine Disorders C00001414
D020149 Manganese Poisoning C00001408
D008133 Long QT Syndrome C00001408
D007859 Learning Disorders C00001408
D010149 Pain, Postoperative C00001414
D018476 Hypokinesia C00001408
D011833 Radiation Injuries, Experimental C00001414
D012130 Respiratory Hypersensitivity C00001414
D012220 Rhinitis C00001414
D006556 Heroin Dependence C00001408
D062787 Drug Overdose C00001408
D014456 Ulcer C00001414
D014581 Urticaria C00001414
D000647 Amnesia C00001424
D019969 Amphetamine-Related Disorders C00001424
D017542 Aneurysm, Ruptured C00001424
D000860 Anoxia C00001424
D001002 Anuria C00001424
D002493 Central Nervous System Diseases C00001408
D001237 Asphyxia C00001424
D001480 Basal Ganglia Diseases C00001408
D001766 Blindness C00001424
D000788 Angina Pectoris, Variant C00001408
D002545 Brain Ischemia C00001424
D002037 Bundle-Branch Block C00001424
D002100 Cachexia C00001424
D006332 Cardiomegaly C00001424
D009202 Cardiomyopathies C00001424
D002543 Cerebral Hemorrhage C00001424
D003922 Diabetes Mellitus, Type 1 C00001424
D004421 Dystonia C00001424
D004827 Epilepsy C00001424
D005901 Glaucoma C00001424
D005921 Glomerulonephritis C00001424
D005923 Glomerulosclerosis, Focal Segmental C00001424
D006470 Hemorrhage C00001424
D006935 Hypercapnia C00001424
D006940 Hyperemia C00001424
D006974 Hypertension, Malignant C00001424
D019954 Neurobehavioral Manifestations C00001426
D006984 Hypertrophy C00001424
D015878 Mydriasis C00001426
D007035 Hypothermia C00001424
D007511 Ischemia C00001424
D007674 Kidney Diseases C00001424
D008113 Liver Neoplasms C00001424
D008114 Liver Neoplasms, Experimental C00001424
D015428 Myocardial Reperfusion Injury C00001424
D009798 Ocular Hypertension C00001424
D009901 Optic Nerve Diseases C00001424
D010243 Paralysis C00001424
D012127 Respiratory Distress Syndrome, Newborn C00001408
D011183 Postoperative Complications C00001424
D011249 Pregnancy Complications, Cardiovascular C00001424
D011297 Prenatal Exposure Delayed Effects C00001424
D011507 Proteinuria C00001424
D011605 Psychoses, Substance-Induced C00001424
D029424 Pulmonary Disease, Chronic Obstructive C00001424
D051437 Renal Insufficiency C00001424
D012120 Respiration Disorders C00001424
D012131 Respiratory Insufficiency C00001424
D012164 Retinal Diseases C00001424
D012206 Rhabdomyolysis C00001424
D018805 Sepsis C00001424
D013035 Spasm C00001424
D013274 Stomach Neoplasms C00001424
D013345 Subarachnoid Hemorrhage C00001424
D017180 Tachycardia, Ventricular C00001424
D014511 Uremia C00001424
D056987 Vasoplegia C00001424
D018754 Ventricular Dysfunction C00001424
D014693 Ventricular Fibrillation C00001424
D000544 Alzheimer Disease C00001429
D000648 Amnesia, Retrograde C00001429
D001022 Aortic Valve Insufficiency C00001429
D001049 Apnea C00001429
D001281 Atrial Fibrillation C00001429
D002659 Child Development Disorders, Pervasive C00001429
D021081 Chronobiology Disorders C00001429
D015140 Dementia, Vascular C00001429
D003967 Diarrhea C00001429
D004195 Disease Models, Animal C00001429
D004487 Edema C00001429
D005355 Fibrosis C00001429
D005483 Flushing C00001429
D006349 Heart Valve Diseases C00001429
D007249 Inflammation C00001429
D043183 Irritable Bowel Syndrome C00001429
D008944 Mitral Valve Insufficiency C00001429
D020230 Serotonin Syndrome C00001429
D020521 Stroke C00001429
D059246 Tachypnea C00001429