Ananas comosus
Species
KNApSAcK Entry
| Organism name | Ananas comosus |
|---|---|
| Genus | Ananas |
| Family | Bromeliaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Ananas comosus |
|---|---|
| Linked NCBI taxonomy ID | 4615 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Bromeliaceae |
|---|---|
| ID | 4613 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Liliopsida |
|---|---|
| ID | 4447 |
Natural Activity
List (111)
| Species | Activity |
|---|---|
| Ananas comosus (L.) Merr. | Abortifacient |
| Ananas comosus (L.) Merr. | Abortifacient |
| Ananas comosus (L.) Merr. | Alterative |
| Ananas comosus (L.) Merr. | Analgesic |
| Ananas comosus (L.) Merr. | Analgesic |
| Ananas comosus (L.) Merr. | Anorectic |
| Ananas comosus (L.) Merr. | Anorectic |
| Ananas comosus (L.) Merr. | Anthelmintic |
| Ananas comosus (L.) Merr. | Antiaggregant |
| Ananas comosus (L.) Merr. | Antiaggregant |
| Ananas comosus (L.) Merr. | Antiallergic |
| Ananas comosus (L.) Merr. | Antiasthmatic |
| Ananas comosus (L.) Merr. | Antibacterial |
| Ananas comosus (L.) Merr. | Anticolitic |
| Ananas comosus (L.) Merr. | Antidiabetic |
| Ananas comosus (L.) Merr. | Antidote |
| Ananas comosus (L.) Merr. | Antiedemic |
| Ananas comosus (L.) Merr. | Antiedemic |
| Ananas comosus (L.) Merr. | Antiencephalotic |
| Ananas comosus (L.) Merr. | Antifertility |
| Ananas comosus (L.) Merr. | Antifertility |
| Ananas comosus (L.) Merr. | AntiIBD |
| Ananas comosus (L.) Merr. | Antiileus |
| Ananas comosus (L.) Merr. | Antiinflammatory |
| Ananas comosus (L.) Merr. | Antiinflammatory |
| Ananas comosus (L.) Merr. | Antimetastatic |
| Ananas comosus (L.) Merr. | AntiMS |
| Ananas comosus (L.) Merr. | Antineurotic |
| Ananas comosus (L.) Merr. | Antinitrosaminic |
| Ananas comosus (L.) Merr. | Antinitrosaminic |
| Ananas comosus (L.) Merr. | Antioxidant |
| Ananas comosus (L.) Merr. | Antioxidant |
| Ananas comosus (L.) Merr. | Antiplatelet |
| Ananas comosus (L.) Merr. | Antipyretic |
| Ananas comosus (L.) Merr. | Antiradicular |
| Ananas comosus (L.) Merr. | Antisarcomic |
| Ananas comosus (L.) Merr. | Antisciatic |
| Ananas comosus (L.) Merr. | Antiscorbutic |
| Ananas comosus (L.) Merr. | Antiscorbutic |
| Ananas comosus (L.) Merr. | Antitendinitic |
| Ananas comosus (L.) Merr. | Antitumor |
| Ananas comosus (L.) Merr. | Antitumor |
| Ananas comosus (L.) Merr. | Antiulcer |
| Ananas comosus (L.) Merr. | Antiulcer |
| Ananas comosus (L.) Merr. | Aperient |
| Ananas comosus (L.) Merr. | Ascaricide |
| Ananas comosus (L.) Merr. | Astringent |
| Ananas comosus (L.) Merr. | Astringent |
| Ananas comosus (L.) Merr. | Bactericide |
| Ananas comosus (L.) Merr. | Carminative |
| Ananas comosus (L.) Merr. | Cerebrotonic |
| Ananas comosus (L.) Merr. | Chitinase |
| Ananas comosus (L.) Merr. | Cholagogue |
| Ananas comosus (L.) Merr. | Cholagogue |
| Ananas comosus (L.) Merr. | Decongestant |
| Ananas comosus (L.) Merr. | Decongestant |
| Ananas comosus (L.) Merr. | Depurative |
| Ananas comosus (L.) Merr. | Depurative |
| Ananas comosus (L.) Merr. | Diaphoretic |
| Ananas comosus (L.) Merr. | Diaphoretic |
| Ananas comosus (L.) Merr. | Digestive |
| Ananas comosus (L.) Merr. | Digestive |
| Ananas comosus (L.) Merr. | Discutient |
| Ananas comosus (L.) Merr. | Discutient |
| Ananas comosus (L.) Merr. | Diuretic |
| Ananas comosus (L.) Merr. | Diuretic |
| Ananas comosus (L.) Merr. | Emmenagogue |
| Ananas comosus (L.) Merr. | Emmenagogue |
| Ananas comosus (L.) Merr. | Estrogenic |
| Ananas comosus (L.) Merr. | Estrogenic |
| Ananas comosus (L.) Merr. | Febrifuge |
| Ananas comosus (L.) Merr. | Fibrinolytic |
| Ananas comosus (L.) Merr. | Fibrinolytic |
| Ananas comosus (L.) Merr. | Fungicide |
| Ananas comosus (L.) Merr. | Hemostat |
| Ananas comosus (L.) Merr. | Hydragogue |
| Ananas comosus (L.) Merr. | Hypotensive |
| Ananas comosus (L.) Merr. | IL-6-Inducer |
| Ananas comosus (L.) Merr. | Immunomodulator |
| Ananas comosus (L.) Merr. | Immunostimulant |
| Ananas comosus (L.) Merr. | iNOS-Inhibitor |
| Ananas comosus (L.) Merr. | Intoxicant |
| Ananas comosus (L.) Merr. | Laxative |
| Ananas comosus (L.) Merr. | Lipolytic |
| Ananas comosus (L.) Merr. | Litholytic |
| Ananas comosus (L.) Merr. | Myocontractant |
| Ananas comosus (L.) Merr. | Myocontractant |
| Ananas comosus (L.) Merr. | Myorelaxant |
| Ananas comosus (L.) Merr. | Myorelaxant |
| Ananas comosus (L.) Merr. | Necrolytic |
| Ananas comosus (L.) Merr. | Necrolytic |
| Ananas comosus (L.) Merr. | NF-Kappa-B-Inhibitor |
| Ananas comosus (L.) Merr. | Parasiticide |
| Ananas comosus (L.) Merr. | Parasiticide |
| Ananas comosus (L.) Merr. | Proteolytic |
| Ananas comosus (L.) Merr. | Proteolytic |
| Ananas comosus (L.) Merr. | Purgative |
| Ananas comosus (L.) Merr. | Refrigerant |
| Ananas comosus (L.) Merr. | Suppurative |
| Ananas comosus (L.) Merr. | Taeniacide |
| Ananas comosus (L.) Merr. | Taenicide |
| Ananas comosus (L.) Merr. | Tonic |
| Ananas comosus (L.) Merr. | Tonic |
| Ananas comosus (L.) Merr. | Uterocontractant |
| Ananas comosus (L.) Merr. | Uterocontractant |
| Ananas comosus (L.) Merr. | Uterotonic |
| Ananas comosus (L.) Merr. | Uterotonic |
| Ananas comosus (L.) Merr. | Vermifuge |
| Ananas comosus (L.) Merr. | Vermifuge |
| Ananas comosus (L.) Merr. | Vulnerary |
| Ananas comosus (L.) Merr. | Vulnerary |
Metabolite list (8)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00006688
|
Peonin
/ Peonidin 3,5-diglucoside / Peonidin 3-glucoside-5-glucoside |
C047592
|
No. 1 | No. 15 |
|
|||
|
C00002378
|
Cyanin
/ Cyanidin 3,5-diglucoside |
No. 1 | No. 15 |
|
||||
|
C00002377
|
Cyanidin 3,5,3'-triglucoside
|
No. 5 | No. 15 |
|
||||
|
C00003776
|
Lutein
/ (all-E)-Lutein / all-trans-(+)-Xanthophyll / (3R,3'R,6'R)-beta,epsilon-Carotene-3,3'-diol |
CHEMBL173929
CHEMBL172477 CHEMBL1559643 CHEMBL1979448 |
D014975
|
4 / 2 / 3 | 7 / 2 | No. 26 | No. 59 |
|
|
C00029585
|
Ikshusterol
/ 7alpha-Hydroxysitosterol / Stigmast-5-ene-3beta,7alpha-diol / (-)-Stigmast-5-ene-3beta,7alpha-diol |
CHEMBL455367
|
C011486
|
No. 53 | No. 11 |
|
||
|
C00001429
|
Serotonin
/ Enteramin / Enteramine / DS substance / Thrombotonin / Thrombocytin / 5-Hydroxytryptamine |
CHEMBL39
CHEMBL1628597 |
D012701
|
78 / 35 / 22 | 32 / 40 | No. 1910 | No. 4 |
|
|
C00030200
|
Ergosterol peroxide
/ Ergosterol 5,8-peroxide / (-)-Ergosterol 5,8-peroxide / 5alpha,8alpha-Epidioxyergosta-6,22-dien-3beta-ol / (-)-5alpha,8alpha-Epidioxyergosta-6,22-dien-3beta-ol |
CHEMBL434750
CHEMBL515808 CHEMBL1801968 CHEMBL1969254 |
C036071
|
1 / 0 / 0 | 1 / 4 | No. 2300 |
|
|
|
C00002780
|
Subaphyllin
|
C065165
|
No. 5072 |
|
Human Protein / Gene in interactions
82 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001429 C00003776 | 0 / 0 |
| Q9UN88 | Gamma-aminobutyric acid receptor subunit theta | GABA-A theta | C00001429 | 0 / 0 |
| O75795 | UDP-glucuronosyltransferase 2B17 | Enzyme | C00001429 | 1 / 0 |
| O15244 | Solute carrier family 22 member 2 | Drug uniporter | C00001429 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001429 | 2 / 0 |
| Q7Z2W7 | Transient receptor potential cation channel subfamily M member 8 | Unclassified protein | C00001429 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00001429 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00001429 | 0 / 3 |
| Q13639 | 5-hydroxytryptamine receptor 4 | Serotonin receptor | C00001429 | 0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00001429 | 0 / 0 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00001429 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00001429 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00001429 | 0 / 0 |
| P49286 | Melatonin receptor type 1B | Melatonin receptor | C00001429 | 0 / 1 |
| P23415 | Glycine receptor subunit alpha-1 | GLR alpha | C00001429 | 1 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001429 | 3 / 2 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00001429 | 1 / 2 |
| P28222 | 5-hydroxytryptamine receptor 1B | Serotonin receptor | C00001429 | 0 / 0 |
| P34969 | 5-hydroxytryptamine receptor 7 | Serotonin receptor | C00001429 | 0 / 0 |
| P47898 | 5-hydroxytryptamine receptor 5A | Serotonin receptor | C00001429 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001429 | 0 / 1 |
| P16662 | UDP-glucuronosyltransferase 2B7 | Enzyme | C00001429 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00003776 | 2 / 3 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00001429 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00001429 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00001429 | 0 / 0 |
| P05164 | Myeloperoxidase | Enzyme | C00001429 | 1 / 2 |
| P28566 | 5-hydroxytryptamine receptor 1E | Serotonin receptor | C00001429 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00001429 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00001429 | 1 / 2 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001429 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00003776 | 0 / 0 |
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00001429 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00001429 | 1 / 0 |
| P46098 | 5-hydroxytryptamine receptor 3A | NS | C00001429 | 0 / 0 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00001429 | 0 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00001429 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00003776 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00001429 | 4 / 2 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00001429 | 2 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00001429 | 0 / 0 |
| P36544 | Neuronal acetylcholine receptor subunit alpha-7 | CHRN alpha | C00001429 | 0 / 0 |
| P48039 | Melatonin receptor type 1A | Melatonin receptor | C00001429 | 0 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00030200 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001429 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00001429 | 0 / 1 |
| P06133 | UDP-glucuronosyltransferase 2B4 | Enzyme | C00001429 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00001429 | 1 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00001429 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00001429 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001429 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001429 | 0 / 1 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00001429 | 5 / 1 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00001429 | 0 / 0 |
| P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00001429 | 1 / 0 |
| P28221 | 5-hydroxytryptamine receptor 1D | Serotonin receptor | C00001429 | 0 / 0 |
| P30939 | 5-hydroxytryptamine receptor 1F | Serotonin receptor | C00001429 | 0 / 0 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00001429 | 0 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00001429 | 1 / 1 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00001429 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001429 | 1 / 0 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00001429 | 3 / 0 |
| P28472 | Gamma-aminobutyric acid receptor subunit beta-3 | GABA-A beta | C00001429 | 1 / 0 |
| P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABA-A alpha | C00001429 | 1 / 1 |
| P48169 | Gamma-aminobutyric acid receptor subunit alpha-4 | GABA-A alpha | C00001429 | 0 / 0 |
| O14764 | Gamma-aminobutyric acid receptor subunit delta | GABA-A delta | C00001429 | 1 / 1 |
| P31644 | Gamma-aminobutyric acid receptor subunit alpha-5 | GABA-A alpha | C00001429 | 0 / 0 |
| Q99928 | Gamma-aminobutyric acid receptor subunit gamma-3 | GABA-A gamma | C00001429 | 0 / 0 |
| P78334 | Gamma-aminobutyric acid receptor subunit epsilon | GABA-A epsilon | C00001429 | 0 / 0 |
| Q8N1C3 | Gamma-aminobutyric acid receptor subunit gamma-1 | GABA-A gamma | C00001429 | 0 / 0 |
| P34903 | Gamma-aminobutyric acid receptor subunit alpha-3 | GABA-A alpha | C00001429 | 0 / 0 |
| O00591 | Gamma-aminobutyric acid receptor subunit pi | GABA-A pi | C00001429 | 0 / 0 |
| P47870 | Gamma-aminobutyric acid receptor subunit beta-2 | GABA-A beta | C00001429 | 0 / 0 |
| P18507 | Gamma-aminobutyric acid receptor subunit gamma-2 | GABA-A gamma | C00001429 | 4 / 2 |
| P18505 | Gamma-aminobutyric acid receptor subunit beta-1 | GABA-A beta | C00001429 | 0 / 0 |
| Q16445 | Gamma-aminobutyric acid receptor subunit alpha-6 | GABA-A alpha | C00001429 | 0 / 0 |
| P47869 | Gamma-aminobutyric acid receptor subunit alpha-2 | GABA-A alpha | C00001429 | 1 / 0 |
| O75751 | Solute carrier family 22 member 3 | Unclassified protein | C00001429 | 0 / 0 |
| Q8WXA8 | 5-hydroxytryptamine receptor 3C | NS | C00001429 | 0 / 0 |
| Q70Z44 | 5-hydroxytryptamine receptor 3D | NS | C00001429 | 0 / 0 |
| O95264 | 5-hydroxytryptamine receptor 3B | NS | C00001429 | 0 / 0 |
| A5X5Y0 | 5-hydroxytryptamine receptor 3E | NS | C00001429 | 0 / 0 |
39 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00001429
C00003776
|
| 6571 | SLC18A2, SVAT, SVMT, VAT2, VMAT2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
C00001429
|
| 1080 | CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) |
C00001429
|
| 2597 | GAPDH, G3PD, GAPD | glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) |
C00001429
|
| 2932 | GSK3B | glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) |
C00001429
|
| 3352 | HTR1D, 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4 | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
C00001429
|
| 3356 | HTR2A, 5-HT2A, HTR2 | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
C00001429
|
| 3359 | HTR3A, 5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3 | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
C00001429
|
| 9177 | HTR3B, 5-HT3B | 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic |
C00001429
|
| 3363 | HTR7, 5-HT7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
C00001429
|
| 3593 | IL12B, CLMF, CLMF2, IL-12B, NKSF, NKSF2 | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) |
C00001429
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00001429
|
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00001429
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00001429
|
| 3690 | ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
C00001429
|
| 4128 | MAOA, MAO-A | monoamine oxidase A (EC:1.4.3.4) |
C00001429
|
| 4353 | MPO | myeloperoxidase (EC:1.11.2.2) |
C00001429
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00001429
|
| 6570 | SLC18A1, CGAT, VAT1, VMAT1 | solute carrier family 18 (vesicular monoamine transporter), member 1 |
C00001429
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00030200
|
| 85413 | SLC22A16, CT2, FLIPT2, OAT6, OCT6, OKB1, dJ261K5.1 | solute carrier family 22 (organic cation/carnitine transporter), member 16 |
C00001429
|
| 6530 | SLC6A2, NAT1, NET, NET1, SLC6A5 | solute carrier family 6 (neurotransmitter transporter), member 2 |
C00001429
|
| 6531 | SLC6A3, DAT, DAT1, PKDYS | solute carrier family 6 (neurotransmitter transporter), member 3 |
C00001429
|
| 6532 | SLC6A4, 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT | solute carrier family 6 (neurotransmitter transporter), member 4 |
C00001429
|
| 6814 | STXBP3, MUNC18-3, MUNC18C, PSP, UNC-18C | syntaxin binding protein 3 |
C00001429
|
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00001429
|
| 6818 | SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) |
C00001429
|
| 134864 | TAAR1, RP11-295F4.9, TA1, TAR1, TRAR1 | trace amine associated receptor 1 |
C00001429
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00001429
|
| 7166 | TPH1, TPRH, TRPH, TPH | tryptophan hydroxylase 1 (EC:1.14.16.4) |
C00001429
|
| 8989 | TRPA1, ANKTM1, FEPS | transient receptor potential cation channel, subfamily A, member 1 |
C00001429
|
| 54578 | UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F | UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) |
C00001429
|
| 7498 | XDH, XO, XOR | xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2) |
C00001429
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00003776
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00003776
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00003776
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00003776
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00003776
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00003776
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (37)
| OMIM | preferred title | UniProt |
|---|---|---|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #103780 | Alcohol dependence |
P14416
P31645 P47869 |
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #612560 | Bone mineral density quantitative trait locus 12; bmnd12 |
O75795
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #607208 | Dravet syndrome |
P18507
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #607681 | Epilepsy, childhood absence, susceptibility to, 2; eca2 |
P18507
|
| #612269 | Epilepsy, childhood absence, susceptibility to, 5; eca5 |
P28472
|
| #613060 | Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 |
O14764
|
| #611136 | Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 |
P14867
|
| #604233 | Generalized epilepsy with febrile seizures plus, type 1; gefsp1 |
P18507
|
| #611277 | Generalized epilepsy with febrile seizures plus, type 3; gefsp3 |
P18507
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #149400 | Hyperekplexia, hereditary 1; hkpx1 |
P23415
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #254600 | Myeloperoxidase deficiency; mpod |
P05164
|
| #159900 | Myoclonic dystonia |
P14416
|
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (25)
| KEGG | name | UniProt |
|---|---|---|
| H00783 | Febrile seizures |
O14764
(related)
P18507 (related) |
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00101 | Other phagocyte defects |
P05164
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P05164
(marker)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00808 | Idiopathic generalized epilepsies (IGEs) |
P14867
(related)
P18507 (related) |
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H00769 | Hyperekplexia |
P23415
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00409 | Type II diabetes mellitus |
P49286
(related)
|
Diseases related to CTD interactions
46 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D001424 | Bacterial Infections |
C00030200
|
| D009369 | Neoplasms |
C00030200
|
| D011471 | Prostatic Neoplasms |
C00030200
|
| D014777 | Virus Diseases |
C00030200
|
| D000544 | Alzheimer Disease |
C00001429
|
| D000648 | Amnesia, Retrograde |
C00001429
|
| D001008 | Anxiety Disorders |
C00001429
|
| D001022 | Aortic Valve Insufficiency |
C00001429
|
| D001049 | Apnea |
C00001429
|
| D001281 | Atrial Fibrillation |
C00001429
|
| D001321 | Autistic Disorder |
C00001429
|
| D001919 | Bradycardia |
C00001429
|
| D002375 | Catalepsy |
C00001429
|
| D002389 | Catatonia |
C00001429
|
| D002659 | Child Development Disorders, Pervasive |
C00001429
|
| D021081 | Chronobiology Disorders |
C00001429
|
| D015140 | Dementia, Vascular |
C00001429
|
| D003967 | Diarrhea |
C00001429
|
| D004195 | Disease Models, Animal |
C00001429
|
| D004487 | Edema |
C00001429
|
| D005355 | Fibrosis |
C00001429
|
| D005483 | Flushing |
C00001429
|
| D006349 | Heart Valve Diseases |
C00001429
|
| D006930 | Hyperalgesia |
C00001429
|
| D006973 | Hypertension |
C00001429
|
| D006976 | Hypertension, Pulmonary |
C00001429
|
| D017379 | Hypertrophy, Left Ventricular |
C00001429
|
| D007022 | Hypotension |
C00001429
|
| D007249 | Inflammation |
C00001429
|
| D043183 | Irritable Bowel Syndrome |
C00001429
|
| D008944 | Mitral Valve Insufficiency |
C00001429
|
| D009135 | Muscular Diseases |
C00001429
|
| D009336 | Necrosis |
C00001429
|
| D009422 | Nervous System Diseases |
C00001429
|
| D010146 | Pain |
C00001429
|
| D011537 | Pruritus |
C00001429
|
| D012640 | Seizures |
C00001429
|
| D020230 | Serotonin Syndrome |
C00001429
|
| D013226 | Status Epilepticus |
C00001429
|
| D013276 | Stomach Ulcer |
C00001429
|
| D020521 | Stroke |
C00001429
|
| D013610 | Tachycardia |
C00001429
|
| D059246 | Tachypnea |
C00001429
|
| D014202 | Tremor |
C00001429
|
| D007939 | Leukemia L1210 |
C00003776
|
| D014605 | Uveitis |
C00003776
|