PCIDB

Falcaria vulgaris

Species

KNApSAcK Entry

Organism name Falcaria vulgaris
Genus Falcaria
Family Apiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Falcaria vulgaris
Linked NCBI taxonomy ID 52469
Linked level species

Family

Family in NCBI taxonomy Apiaceae
ID 4037

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (23)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00002724 External link 512 Heriguard
/ Chlorogenic acid
/ 3-O-Caffeoylquinic acid
CHEMBL284616
CHEMBL230481
CHEMBL249450
CHEMBL1332980
CHEMBL1394423
CHEMBL1419611
CHEMBL1473644
CHEMBL1552319
D002726
30 / 19 / 22 37 / 9 No. 314 No. 6
C00000805 External link 512 alpha-Pinene
CHEMBL442565
C005451
3 / 3 / 2 0 / 1 No. 476 No. 35
C00000816 External link 512 beta-Pinene
CHEMBL501351
C010789
No. 476 No. 35
C00048432 External link 512 Isoborneol
CHEMBL296404
CHEMBL486208
CHEMBL1097205
CHEMBL1968981
8 / 5 / 1 No. 649 No. 35
C00003028 External link 512 Borneol
/ (+/-)-Borneol
CHEMBL296404
CHEMBL486208
CHEMBL1097205
CHEMBL1968981
8 / 5 / 1 No. 649 No. 35
C00000856 External link 512 4-Hydroxybenzoic acid
/ p-Hydroxybenzoic acid
CHEMBL441343
C038193
21 / 7 / 16 2 / 1 No. 817 No. 81
C00002668 External link 512 Protocatechuic acid
/ 3,4-Dihydroxybenzoic acid
CHEMBL37537
C009091
33 / 19 / 19 2 / 0 No. 817 No. 81
C00000823 External link 512 Limonene
CHEMBL15799
CHEMBL449062
C008281
7 / 21 / 48 6 / 6 No. 848 No. 35
C00002499 External link 512 Scopoletin
CHEMBL71851
D012603
48 / 37 / 34 9 / 0 No. 864 No. 25
C00000615 External link 512 Caffeic acid
CHEMBL145
CHEMBL1320034
68 / 64 / 63 No. 904 No. 6
C00000152 External link 512 p-Coumaric acid
CHEMBL66879
CHEMBL2336752
C032171
23 / 13 / 18 6 / 1 No. 904 No. 6
C00001284 External link 512 Panaxynol
/ Falcarinol
/ (-)-Falcarinol
CHEMBL71260
CHEMBL368712
C018541
0 / 2 No. 940 No. 69
C00002503 External link 512 Umbelliferon
/ Umbelliferone
/ 7-Hydroxycoumarin
CHEMBL51628
C031477
39 / 33 / 32 9 / 0 No. 1030 No. 25
C00002682 External link 512 Vanillic acid
/ 3-Methoxy-4-hydroxybenzoic acid
CHEMBL120568
D014641
5 / 3 / 3 5 / 0 No. 1073
C00002674 External link 512 Syringic acid
/ 4-Hydroxy-3,5-dimethoxybenzoic acid
CHEMBL1414
C001945
12 / 3 / 5 No. 1073
C00001285 External link 512 Falcarinone
CHEMBL1973480
No. 1184
C00002743 External link 512 Ferulic acid
/ 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid
CHEMBL32749
C004999
110 / 52 / 40 16 / 6 No. 1366 No. 6
C00048335 External link 512 Bisabolene
No. 1469 No. 38
C00003051 External link 512 alpha-Phellandrene
CHEMBL455041
C005403
No. 1898 No. 35
C00003045 External link 512 Fenchone
/ (+)-Fenchone
C027327
No. 1921 No. 35
C00003040 External link 512 p-Cymene
CHEMBL442915
C007210
No. 2172 No. 35
C00003029 External link 512 Camphene
CHEMBL506889
CHEMBL510535
C019286
No. 2460 No. 35
C00002713 External link 512 Anethole
CHEMBL452630
CHEMBL1468832
C006578
6 / 21 / 49 16 / 13 No. 2748 No. 6

Human Protein / Gene in interactions

200 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O43570 Carbonic anhydrase 12 Lyase C00000152 C00000615 C00000856 C00002499 C00002503 C00002668 C00002674 C00002743 1 / 2
P00918 Carbonic anhydrase 2 Lyase C00000152 C00000615 C00000856 C00002499 C00002503 C00002668 C00002674 C00002743 1 / 2
P00915 Carbonic anhydrase 1 Lyase C00000152 C00000615 C00000856 C00002499 C00002503 C00002668 C00002674 C00002743 0 / 0
P15121 Aldose reductase Enzyme C00000152 C00000615 C00002499 C00002503 C00002668 C00002674 C00002682 C00002724 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00000152 C00000615 C00000856 C00002499 C00002503 C00002668 C00002674 C00002743 0 / 1
P43166 Carbonic anhydrase 7 Lyase C00000152 C00000615 C00000856 C00002499 C00002668 C00002674 C00002743 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00000615 C00002499 C00002503 C00002668 C00002713 C00002724 C00002743 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00000152 C00000615 C00000823 C00002499 C00002503 C00002724 C00002743 0 / 3
Q9ULX7 Carbonic anhydrase 14 Lyase C00000152 C00000615 C00000856 C00002668 C00002674 C00002743 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00000152 C00000615 C00000856 C00002668 C00002674 C00002743 1 / 1
P23280 Carbonic anhydrase 6 Lyase C00000152 C00000615 C00000856 C00002668 C00002674 C00002743 0 / 0
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00002499 C00002503 C00002743 C00003028 C00048432 3 / 0
P03372 Estrogen receptor NR3A1 C00000152 C00000615 C00002668 C00002682 C00002743 1 / 1
Q9HAW9 UDP-glucuronosyltransferase 1-8 Enzyme C00000856 C00002499 C00002503 C00003028 C00048432 0 / 0
O75496 Geminin Unclassified protein C00002499 C00002503 C00002668 C00002724 C00002743 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00000615 C00002499 C00002503 C00002713 C00002724 0 / 0
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00000152 C00000615 C00002668 C00002724 C00002743 3 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00000856 C00002499 C00002724 C00003028 C00048432 0 / 0
P54855 UDP-glucuronosyltransferase 2B15 Enzyme C00002499 C00002503 C00002743 C00003028 C00048432 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000615 C00002499 C00002713 C00002724 C00002743 0 / 1
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00002499 C00002503 C00002743 C00003028 C00048432 5 / 1
P07451 Carbonic anhydrase 3 Lyase C00000152 C00000615 C00000856 C00002674 C00002743 0 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00000152 C00000615 C00000856 C00002674 C00002743 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00000152 C00000615 C00000856 C00002674 C00002743 0 / 0
P14679 Tyrosinase Oxidoreductase C00000152 C00000615 C00002503 C00002743 4 / 2
P10253 Lysosomal alpha-glucosidase Hydrolase C00000615 C00002499 C00002503 C00002668 1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000615 C00002499 C00002724 C00002743 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00000615 C00002499 C00002503 C00002724 3 / 3
Q9Y4X1 UDP-glucuronosyltransferase 2A1 Enzyme C00002499 C00002503 C00003028 C00048432 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000615 C00002499 C00002724 C00002743 1 / 1
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00000856 C00002724 C00003028 C00048432 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00000615 C00000805 C00002713 C00002724 3 / 2
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00000152 C00000615 C00000856 C00002743 1 / 8
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000615 C00002499 C00002724 C00002743 0 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000615 C00002499 C00002724 C00002743 1 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00000615 C00002499 C00002503 C00002743 1 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00000615 C00002503 C00002668 C00002724 0 / 0
P02545 Prelamin-A/C Unclassified protein C00000615 C00000823 C00002713 11 / 10
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00000615 C00002499 C00002503 1 / 2
Q8TDS4 Hydroxycarboxylic acid receptor 2 Hydroxycarboxylic acid receptor C00000152 C00000615 C00002743 0 / 0
O00255 Menin Unclassified protein C00000615 C00002499 C00002503 2 / 5
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00000615 C00002503 C00002724 1 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00000615 C00002499 C00002724 0 / 0
P29466 Caspase-1 C14 C00002499 C00002503 C00002743 0 / 0
P03956 Interstitial collagenase M10A C00000615 C00002668 C00002743 0 / 1
P06280 Alpha-galactosidase A Enzyme C00000615 C00002499 C00002503 1 / 1
P28482 Mitogen-activated protein kinase 1 Erk C00000615 C00000805 C00002743 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00000615 C00002499 C00002503 2 / 2
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00000615 C00002724 C00002743 2 / 2
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00000615 C00002499 C00002668 0 / 0
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00000856 C00002499 C00002503 0 / 0
P22303 Acetylcholinesterase Hydrolase C00002499 C00002503 C00002743 1 / 0
P14780 Matrix metalloproteinase-9 M10A C00000615 C00002668 C00002743 2 / 2
O60218 Aldo-keto reductase family 1 member B10 Enzyme C00000152 C00000615 C00002724 0 / 0
P16662 UDP-glucuronosyltransferase 2B7 Enzyme C00003028 C00048432 0 / 0
Q99700 Ataxin-2 Unclassified protein C00002499 C00002503 1 / 1
P52895 Aldo-keto reductase family 1 member C2 Enzyme C00000152 C00000615 1 / 0
P51580 Thiopurine S-methyltransferase Enzyme C00000856 C00002682 1 / 1
P55210 Caspase-7 C14 C00002499 C00002503 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00002668 C00002682 0 / 0
Q9GZT9 Egl nine homolog 1 Enzyme C00000615 C00002668 1 / 1
Q00796 Sorbitol dehydrogenase Enzyme C00002499 C00002503 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00000615 C00002724 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00000615 C00002724 0 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00000615 C00002743 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00000615 C00002668 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00000823 C00002724 0 / 0
P17516 Aldo-keto reductase family 1 member C4 Enzyme C00000152 C00000615 1 / 0
Q04828 Aldo-keto reductase family 1 member C1 Enzyme C00000152 C00000615 0 / 0
P08253 72 kDa type IV collagenase M10A C00000615 C00002668 1 / 3
P06239 Tyrosine-protein kinase Lck Src C00002724 C00002743 0 / 1
P04637 Cellular tumor antigen p53 Transcription Factor C00000823 C00002713 7 / 37
P06746 DNA polymerase beta Enzyme C00000615 C00002668 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00002724 C00002743 0 / 1
P04406 Glyceraldehyde-3-phosphate dehydrogenase Enzyme C00002499 C00002503 0 / 0
Q12794 Hyaluronidase-1 Enzyme C00000615 C00002743 1 / 2
P04062 Glucosylceramidase Enzyme C00002499 C00002503 6 / 4
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00000615 C00002499 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00002499 C00002503 0 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00000615 C00000823 3 / 1
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00000615 C00002499 0 / 0
P42330 Aldo-keto reductase family 1 member C3 Enzyme C00000152 C00000615 0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00000615 0 / 0
P39748 Flap endonuclease 1 Enzyme C00002503 0 / 0
P17252 Protein kinase C alpha type Alpha C00002743 0 / 0
P42858 Huntingtin Unclassified protein C00002682 1 / 1
P16581 E-selectin Adhesion C00002668 0 / 0
Q06124 Tyrosine-protein phosphatase non-receptor type 11 Tyr C00000615 4 / 2
P22894 Neutrophil collagenase M10A C00002668 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00002743 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00002743 0 / 0
P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Oxidoreductase C00002503 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00002743 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00002743 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00002743 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00002743 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00002743 0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00002743 0 / 0
P28845 Corticosteroid 11-beta-dehydrogenase isozyme 1 Enzyme C00002503 1 / 1
P25101 Endothelin-1 receptor Endothelin receptor C00002743 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00002743 0 / 0
P10145 Interleukin-8 Secreted protein C00002724 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00002743 1 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00002743 0 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00002743 0 / 0
P08311 Cathepsin G S1A C00002743 0 / 0
P07711 Cathepsin L1 C1A C00002668 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00002743 1 / 0
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00002724 1 / 2
P27361 Mitogen-activated protein kinase 3 Erk C00002743 0 / 0
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00002743 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00002499 7 / 3
Q04206 Transcription factor p65 Transcription Factor C00002499 0 / 0
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00002668 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00002503 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00002743 1 / 0
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00002743 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00002743 0 / 0
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00002743 0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00002743 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00002743 2 / 0
P80404 4-aminobutyrate aminotransferase, mitochondrial Transferase C00000856 1 / 1
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00002743 5 / 9
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00002743 1 / 0
P21452 Substance-K receptor Neurokinin receptor C00002743 0 / 0
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00002724 0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00002743 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00002743 3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00002743 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00002743 1 / 1
P35236 Tyrosine-protein phosphatase non-receptor type 7 Tyr C00000615 0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00002743 1 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00002743 0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00002743 2 / 1
P56817 Beta-secretase 1 A1A C00002503 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00002743 0 / 0
P33765 Adenosine receptor A3 Adenosine receptor C00002743 0 / 0
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00000823 0 / 0
P08246 Neutrophil elastase S1A C00002743 2 / 1
P51692 Signal transducer and activator of transcription 5B Unclassified protein C00002724 1 / 1
P29274 Adenosine receptor A2a Adenosine receptor C00002743 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00002743 0 / 0
Q01453 Peripheral myelin protein 22 Unclassified protein C00000615 5 / 2
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00000805 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00002743 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00002743 0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00002743 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00002743 0 / 0
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00002743 1 / 0
P14416 D(2) dopamine receptor Dopamine receptor C00002743 2 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00002743 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00002743 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00002743 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00002743 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00002743 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00002743 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00002743 0 / 0
Q9HAW7 UDP-glucuronosyltransferase 1-7 Enzyme C00000856 0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00002743 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00002499 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00002743 0 / 0
P14151 L-selectin Adhesion C00002668 0 / 0
P16109 P-selectin Adhesion C00002668 1 / 0
P06241 Tyrosine-protein kinase Fyn Src C00002743 0 / 0
Q9UQ49 Sialidase-3 Enzyme C00000856 0 / 0
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00002743 0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00002743 0 / 0
P51452 Dual specificity protein phosphatase 3 Ser_Thr_Tyr C00000615 0 / 0
P02768 Serum albumin Secreted protein C00002668 0 / 0
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00002743 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00002743 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00002743 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00000615 0 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00002743 0 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00002743 1 / 1
Q01959 Sodium-dependent dopamine transporter Dopamine C00002743 1 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00002743 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00002743 0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00002743 1 / 1
O75795 UDP-glucuronosyltransferase 2B17 Enzyme C00002499 1 / 0
P35367 Histamine H1 receptor Histamine receptor C00002743 0 / 0
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00002743 0 / 0
P08254 Stromelysin-1 M10A C00002668 1 / 0
P25021 Histamine H2 receptor Histamine receptor C00002743 0 / 0
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme C00002503 1 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00002743 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00000615 0 / 0
P24298 Alanine aminotransferase 1 Enzyme C00000615 0 / 0
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00002743 0 / 1
P46063 ATP-dependent DNA helicase Q1 Enzyme C00002499 0 / 0
P42224 Signal transducer and activator of transcription 1-alpha/beta Unclassified protein C00002724 3 / 3
Q8N1Q1 Carbonic anhydrase 13 Lyase C00002499 0 / 0
P51649 Succinate-semialdehyde dehydrogenase, mitochondrial Oxidoreductase C00000856 1 / 1
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00000823 0 / 0
P55789 FAD-linked sulfhydryl oxidase ALR Enzyme C00002499 1 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00002668 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00002668 1 / 4
P07900 Heat shock protein HSP 90-alpha Other cytosolic protein C00000615 0 / 0
P08238 Heat shock protein HSP 90-beta Other cytosolic protein C00000615 0 / 0
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00002743 0 / 0

80 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00002499 C00002682 C00002724 C00002743
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00002499 C00002682 C00002724 C00002743
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00002499 C00002682 C00002724 C00002743
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) C00002499 C00002682 C00002724 C00002743
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00000152 C00000823 C00002743
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) C00000152 C00002682 C00002724
7299 TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 tyrosinase (EC:1.14.18.1) C00000152 C00002724 C00002743
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00000152 C00000856 C00002503
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00000152 C00002743
54600 UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) C00002499 C00002503
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00000823 C00002503
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00002713 C00002743
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00002713 C00002743
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00000152 C00002743
7366 UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) C00002499 C00002503
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00002503 C00002743
2896 GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN granulin C00002724
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00002713
3551 IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) C00002713
5604 MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1 mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) C00002713
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00002713
4313 MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) C00002713
4318 MMP9, CLG4B, GELB, MANDP2, MMP-9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) C00002713
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00002713
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00002713
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00002713
5328 PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA plasminogen activator, urokinase (EC:3.4.21.73) C00002713
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00002713
7076 TIMP1, CLGI, EPA, EPO, HCI, TIMP TIMP metallopeptidase inhibitor 1 C00002713
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00002713
6319 SCD, FADS5, MSTP008, SCD1, SCDOS stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) C00002743
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00000823
3265 HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1 Harvey rat sarcoma viral oncogene homolog C00000823
4852 NPY, PYY4 neuropeptide Y C00000823
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00000823
1312 COMT catechol-O-methyltransferase (EC:2.1.1.6) C00002668
2023 ENO1, ENO1L1, MPB1, NNE, PPH enolase 1, (alpha) (EC:4.2.1.11) C00002668
8644 AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) C00002503
8574 AKR7A2, AFAR, AFAR1, AFB1-AR1, AKR7 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (EC:1.1.1.n11) C00002503
581 BAX, BCL2L4 BCL2-associated X protein C00002503
1548 CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) C00002503
5925 RB1, OSRC, RB, p105-Rb, pRb, pp110 retinoblastoma 1 C00002743
5742 PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00002743
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00002743
23621 BACE1, ASP2, BACE, HSPC104 beta-site APP-cleaving enzyme 1 (EC:3.4.23.46) C00002743
3952 LEP, LEPD, OB, OBS leptin C00000856
47 ACLY, ACL, ATPCL, CLATP ATP citrate lyase (EC:2.3.3.8) C00002724
358 AQP1, AQP-CHIP, CHIP28, CO aquaporin 1 C00002724
360 AQP3, AQP-3, GIL aquaporin 3 (Gill blood group) C00002724
367 AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM androgen receptor C00002724
960 CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1 CD44 molecule (Indian blood group) C00002724
999 CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO cadherin 1, type 1, E-cadherin (epithelial) C00002724
1277 COL1A1, OI4 collagen, type I, alpha 1 C00002724
4512 COX1, COI, MTCO1, MT-CO1 cytochrome c oxidase subunit I C00002724
114757 CYGB, HGB, STAP cytoglobin C00002724
1830 DSG3, CDHF6, PVA desmoglein 3 C00002724
1950 EGF, HOMG4, URG epidermal growth factor C00002724
2200 FBN1, ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2 fibrillin 1 C00002724
2201 FBN2, CCA, DA9 fibrillin 2 C00002724
2246 FGF1, AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1 fibroblast growth factor 1 (acidic) C00002724
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00002713
3036 HAS1, HAS hyaluronan synthase 1 (EC:2.4.1.212) C00002724
3315 HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27 heat shock 27kDa protein 1 C00002724
3552 IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 interleukin 1, alpha C00002724
3852 KRT5, CK5, DDD, DDD1, EBS2, K5, KRT5A keratin 5 C00002724
4157 MC1R, CMM5, MSH-R, SHEP2 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) C00002724
5241 PGR, NR3C3, PR progesterone receptor C00002724
8985 PLOD3, LH3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (EC:1.14.11.4) C00002724
5468 PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma peroxisome proliferator-activated receptor gamma C00002724
5886 RAD23A, HHR23A, HR23A RAD23 homolog A (S. cerevisiae) C00002724
5914 RARA, NR1B1, RAR retinoic acid receptor, alpha C00002724
6256 RXRA, NR2B1 retinoid X receptor, alpha C00002724
6649 SOD3, EC-SOD superoxide dismutase 3, extracellular (EC:1.15.1.1) C00002724
6716 SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (EC:1.3.1.22) C00002724
7178 TPT1, HRF, TCTP, p02, p23 tumor protein, translationally-controlled 1 C00002724
7295 TXN, TRDX, TRX, TRX1 thioredoxin C00002724
7306 TYRP1, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN tyrosinase-related protein 1 (EC:1.14.18.-) C00002724
54658 UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) C00002499
54578 UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) C00002499
7508 XPC, RAD4, XP3, XPCC xeroderma pigmentosum, complementation group C C00002499

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (132)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#614279 46,xy sex reversal 8; srxy8 P17516
P52895
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#103780 Alcohol dependence P08172
P14416
P31645
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#218030 Apparent mineralocorticoid excess; ame P80365
#600807 Asthma, susceptibility to Q13093
#209950 Atypical mycobacteriosis, familial P42224
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
#612560 Bone mineral density quantitative trait locus 12; bmnd12 O75795
#300615 Brunner syndrome P21397
#614162 Candidiasis, familial, 7; candf7 P42224
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#118300 Charcot-marie-tooth disease and deafness Q01453
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#118220 Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a Q01453
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#604931 Cortisone reductase deficiency 1; cortrd1 P28845
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#609820 Erythrocytosis, familial, 3; ecyt3 Q9GZT9
#133239 Esophageal cancer P04637
#615363 Estrogen resistance; estrr P03372
#301500 Fabry disease P06280
#600274 Frontotemporal dementia; ftd P10636
#613163 Gaba-transaminase deficiency P80404
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#143500 Gilbert syndrome P22309
P22310
#137800 Glioma susceptibility 1; glm1 P04626
#232300 Glycogen storage disease ii P10253
#245590 Growth hormone insensitivity with immunodeficiency P51692
#139393 Guillain-barre syndrome, familial; gbs Q01453
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#143100 Huntington disease; hd P42858
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#145900 Hypertrophic neuropathy of dejerine-sottas Q01453
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#147050 Ige responsiveness, atopic; iger Q13093
#603932 Intervertebral disc disease; idd P14780
#607785 Juvenile myelomonocytic leukemia; jmml Q06124
#151100 Leopard syndrome 1 Q06124
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
P04637
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#174800 Mccune-albright syndrome; mas P63092
#300705 Mental retardation, x-linked 17; mrx17 Q99714
%300852 Mental retardation, x-linked 88; mrx88 P50052
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#156250 Metachondromatosis; metcds Q06124
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#601492 Mucopolysaccharidosis, type ix; mps9 Q12794
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#613796 Mycobacterial and viral infections, susceptibility to, autosomal recessive P42224
#159900 Myoclonic dystonia P14416
#613076 Myopathy, mitochondrial progressive, with congenital cataract, hearing loss, and developmental delay P55789
#162500 Neuropathy, hereditary, with liability to pressure palsies; hnpp Q01453
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#163950 Noonan syndrome 1; ns1 Q06124
#601665 Obesity P32245
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#166350 Osseous heteroplasia, progressive; poh P63092
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#260500 Papilloma of choroid plexus; cpp P04637
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#600852 Retinitis pigmentosa 17; rp17 P22748
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601367 Stroke, ischemic P16109
#271980 Succinic semialdehyde dehydrogenase deficiency; ssadhd P51649
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#610460 Thiopurine s-methyltransferase deficiency P51580
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#610379 West nile virus, susceptibility to P51681
#278300 Xanthinuria, type i P47989
#112100 Yt blood group antigen P22303

KEGG DISEASE (115)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
Q16790 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P40763 (related)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P04637 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
P04637 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
P04637 (related)
P08253 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q01453 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
P04637 (related)
Q92731 (marker)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04626 (related)
P04637 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P04637 (related)
H00046 Cholangiocarcinoma P04626 (related)
P04637 (related)
P35354 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P08253 (related)
P14780 (related)
P35354 (related)
H00029 Vulvar cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00044 Cancer of the anal canal P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00125 Fabry disease P06280 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00548 Brunner syndrome P21397 (related)
H00208 Hyperbilirubinemia P22309 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01111 Cortisone reductase deficiency (CRD) P28845 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
H00089 IFN-gamma/IL-12 axis P42224 (related)
H00363 Candidiasis P42224 (related)
H01109 Chronic mucocutaneous candidiasis (CMC) P42224 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00192 Xanthinuria P47989 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
Q99714 (related)
H00964 Thiopurine S-methyltransferase deficiency (TPMT deficiency) P51580 (related)
H00835 Succinic semialdehyde dehydrogenase (SSADH) deficiency P51649 (related)
H00931 Growth hormone insensitivity with immunodeficiency P51692 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)
H01257 GABA-transaminase deficiency P80404 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H01296 Hereditary neuropathy with liability to pressure palsies (HNPP) Q01453 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00523 Noonan syndrome and related disorders Q06124 (related)
H01018 Metachondromatosis Q06124 (related)
H00133 Mucopolysaccharidosis type IX (MPS9) Q12794 (related)
H00421 Mucopolysaccharidosis (MPS) Q12794 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00236 Congenital polycythemia Q9GZT9 (related)

Diseases related to CTD interactions

31 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003877 Dermatitis, Contact C00000805
C00002713
C00000823
D008545 Melanoma C00002743
C00000152
C00002724
D056486 Drug-Induced Liver Injury C00002713
C00002724
D008107 Liver Diseases C00002713
C00000823
D013276 Stomach Ulcer C00002713
C00000823
D007249 Inflammation C00002743
C00002713
D010243 Paralysis C00002713
D001919 Bradycardia C00002713
D002286 Carcinoma, Ehrlich Tumor C00002713
D008106 Liver Cirrhosis, Experimental C00002743
D005767 Gastrointestinal Diseases C00002713
D007022 Hypotension C00002713
D050197 Atherosclerosis C00002743
D008113 Liver Neoplasms C00002713
D009362 Neoplasm Metastasis C00002713
D009203 Myocardial Infarction C00002743
D002252 Carbon Tetrachloride Poisoning C00002743
D013927 Thrombosis C00002713
D007674 Kidney Diseases C00000823
D008114 Liver Neoplasms, Experimental C00000823
D008569 Memory Disorders C00000823
D002545 Brain Ischemia C00001284
D015427 Reperfusion Injury C00001284
D012220 Rhinitis C00000856
D000647 Amnesia C00002724
D006937 Hypercholesterolemia C00002724
D006951 Hyperlipoproteinemias C00002724
D015228 Hypertriglyceridemia C00002724
D052456 Hypoalphalipoproteinemias C00002724
D009336 Necrosis C00002724
D015431 Weight Loss C00002724