Species

KNApSAcK Entry

Organism name Beta vulgaris L. var. saccharifera
Genus Beta
Family Chenopodiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Amaranthaceae
Linked NCBI taxonomy ID 3563
Linked level family

Family

Family in NCBI taxonomy Amaranthaceae
ID 3563

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000152 External link 512 p-Coumaric acid
CHEMBL66879
CHEMBL2336752
C032171
23 / 13 / 18 6 / 1 No. 904 No. 6

Human Protein / Gene in interactions

23 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P17516 Aldo-keto reductase family 1 member C4 Enzyme C00000152 1 / 0
O60218 Aldo-keto reductase family 1 member B10 Enzyme C00000152 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00000152 0 / 3
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00000152 3 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00000152 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00000152 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00000152 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00000152 1 / 2
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00000152 1 / 8
P23280 Carbonic anhydrase 6 Lyase C00000152 0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00000152 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00000152 1 / 2
P42330 Aldo-keto reductase family 1 member C3 Enzyme C00000152 0 / 0
Q8TDS4 Hydroxycarboxylic acid receptor 2 Hydroxycarboxylic acid receptor C00000152 0 / 0
P15121 Aldose reductase Enzyme C00000152 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00000152 0 / 0
P14679 Tyrosinase Oxidoreductase C00000152 4 / 2
Q16790 Carbonic anhydrase 9 Lyase C00000152 0 / 1
Q04828 Aldo-keto reductase family 1 member C1 Enzyme C00000152 0 / 0
P03372 Estrogen receptor NR3A1 C00000152 1 / 1
P52895 Aldo-keto reductase family 1 member C2 Enzyme C00000152 1 / 0
P07451 Carbonic anhydrase 3 Lyase C00000152 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00000152 1 / 1

6 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00000152
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00000152
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) C00000152
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00000152
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00000152
7299 TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 tyrosinase (EC:1.14.18.1) C00000152

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#614279 46,xy sex reversal 8; srxy8 P17516
P52895
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#600807 Asthma, susceptibility to Q13093
#615363 Estrogen resistance; estrr P03372
#143860 Hyperchlorhidrosis, isolated O43570
#147050 Ige responsiveness, atopic; iger Q13093
#211980 Lung cancer P00533
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#600852 Retinitis pigmentosa 17; rp17 P22748
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679

KEGG DISEASE (18)

KEGG name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
H00022 Bladder cancer P00533 (related)
H00028 Choriocarcinoma P00533 (related)
H00030 Cervical cancer P00533 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00026 Endometrial Cancer P03372 (marker)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D008545 Melanoma C00000152