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Transcription Machinery - Cryptosporidium parvum
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AEukaryotic type
B RNA polymerase II system
C RNA polymerase II
D Core subunits
E cgd3_2620 DNA-directed RNA polymerase,possible RNA polymerase A/beta'/A'' subunit, long PHYSPTS repeat K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
E cgd7_3720 RNA polymerase beta subunit K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
E cgd1_2710 RNA polymerase II B3 subunit K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
E cgd7_4370 RNA polymerase II K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
D Pol II specific subunits
E cgd3_4320 hypothetical protein K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
E cgd2_2970 DNA-directed RNA polymerase II K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E cgd3_1870 DNA-directed RNA polymerase 2 subunit K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
D Pol I, II, III common subunits
E cgd2_980 DNA-directed RNA polymerase 2 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
E cgd7_4770 DNA-directed RNA polymerase subunit K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
E cgd1_2260 RNA polymerase II B8 subunit K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
E cgd7_3240 transcription activator K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E cgd4_3260 DNA-directed RNA polymerases I, II, and III 8.3 kda polypeptide K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
D Pol IV and V specific subunits
C Basal transcription factors
D TFIIA
E cgd5_4200 transcription initiation factor IIA K03123 TFIIA2; transcription initiation factor TFIIA small subunit
D TFIIB
E cgd8_880 transcription initiation factor TFIIB Sua7p; ZnR+2cyclins K03124 TFIIB; transcription initiation factor TFIIB
D TFIID
E cgd8_2030 TATA-box factor binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
E cgd4_650 ZnKn (C2HC)+Athook+bromo domain protein, Taf250, transcription initiation factor IID K03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
E cgd1_2600 transcription factor TAF5p, TBP associated protein involved in transcription K03130 TAF5; transcription initiation factor TFIID subunit 5
D TFIIE
D TFIIF
D TFIIH
E cgd3_3110 transcription factor TFIIH with a vWA domain K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E cgd6_5040 transcription factor K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E cgd2_2060 possible transcription factor TFIIH K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E cgd8_1940 RAD25, helicase involved in DNA repair K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E cgd7_820 RAD3'DEXDc+HELICc protein' K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E cgd7_430 cyclin-dependent kinase-related kinase K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E cgd1_3300 ring domain protein K10842 MNAT1; CDK-activating kinase assembly factor MAT1
E cgd1_3310 cyclin domain protein, possible cyclin H K06634 CCNH; cyclin H
C Mediator complex
D Head
E cgd5_2520 hypothetical protein K15128 MED6; mediator of RNA polymerase II transcription subunit 6
D Middle
E cgd1_2800 hypothetical protein K15148 MED7; mediator of RNA polymerase II transcription subunit 7
E cgd3_3300 SOH1 family protein K15153 MED31; mediator of RNA polymerase II transcription subunit 31
D Tail
D CDK-module
E cgd2_3890 Ser/Thr protein kinase K02208 CDK8_11; cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23]
D Other mediators
C Coactivators
D SAGA/TFTC/STAGA complex
E cgd3_3190 GCN5 like acetylase + bromodomain K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E cgd6_1740 Tra1p-like; C-terminal FAT domain plus phoshoinositide 3-kinase domain; very large protein K08874 TRRAP; transformation/transcription domain-associated protein
E cgd4_880 ADA2 ortholog with a ZZ finger, SANT domain and a SWIRM domain K11314 TADA2A; transcriptional adapter 2-alpha
E cgd1_2600 transcription factor TAF5p, TBP associated protein involved in transcription K03130 TAF5; transcription initiation factor TFIID subunit 5
E cgd1_3670 CHD3 ortholog with 2x chromodomains plus SNF2 ATpase (2chromo+helicase+Znf_NFX) K11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]
E cgd8_4340 ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
E cgd8_4240 possible spliceosome factor K12830 SF3B3; splicing factor 3B subunit 3
D BAF/PBAF complex
E cgd8_2300 brahma like protein with a HSA domain, SNF2 like helicase and a bromo domain K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
E cgd2_3700 SWI/SNF related transcriptional regulator ATpase K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
E cgd2_1740 RSC8 ortholog with a swirm domain, ZZ finger and Myb K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
E cgd3_840 RSC6/BAF60A ortholog with a SWIB domain K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
E cgd8_2200 BRG1/brm-associated factor 53A like actin K11340 ACTL6A; actin-like protein 6A
D SWI/SNF complex
D RSC complex
D Others
C Other transcription-related factors
D Transcription elongation factors
E cgd8_4400 transcription elongation factor TFIIS K03145 TFIIS; transcription elongation factor S-II
E cgd2_2820 transcription factor K15171 SUPT4H1; transcription elongation factor SPT4
E cgd6_4650 5kows transcription initiation protein SPT5 K15172 SUPT5H; transcription elongation factor SPT5
E cgd6_5250 transcription elongation factor, SPT6-like K11292 SUPT6H; transcription elongation factor SPT6
D Transcription termination factor
E cgd8_460 cleavage and polyadenylation specifity factor protein, CPSF metallobeta-lactamase K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E cgd6_1730 cleavage and polyadenylation specificity factor 4-like; 3x Zn C3H1 domains K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E cgd5_1070 CCCH RNA binding domain involved in RNA metabolism K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E cgd7_2670 serine/threonine protein phosphatase K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E cgd8_2250 Rat1 Kar1/Rat1 like 5'-3' exonuclease K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D PAF1 complex
E cgd4_2010 hypothetical protein K15175 CDC73; parafibromin
E cgd5_3010 hypothetical protein K15178 RTF1; RNA polymerase-associated protein RTF1
D NELF complex
D Super elongation complex (SEC)
D Little elongation complex (LEC)
D Brd4/P-TEFb complex
D BUR kinase complex
D CTDK-I complex
D 7SK RNP complex
D DBIRD complex
D Others
E cgd8_4810 RNA pol II carboxy terminal domain phosphatase of the HAD superfamily with a BRCT domain at the C-terminus K15732 CTDP1; RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16]
E cgd7_4250 RNA pol II carboxy terminal domain phosphatase of the HAD superfamily with a BRCT domain at the C-terminus K15732 CTDP1; RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16]
E cgd2_3810 hypothetical protein K15731 CTDSP; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16]
E cgd5_1150 iwsip-like protein K17498 SPN1; transcription factor SPN1
E cgd3_3390 hypothetical protein K20826 RPAP1; RNA polymerase II-associated protein 1
E cgd5_1900 XPA binding protein 1 K24104 GPN; GPN-loop GTPase
E cgd6_4270 MinD type ATpase K24104 GPN; GPN-loop GTPase
E cgd7_80 XPA1 binding protein-like GTpase K24104 GPN; GPN-loop GTPase
B RNA polymerase III system
C RNA polymerase III
D Core subunits
E cgd6_3290 DNA-directed RNA polymerase III C1 subunit K03018 RPC1; DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]
E cgd8_170 DNA-directed RNA polymerase beta subunit K03021 RPC2; DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6]
E cgd8_300 RNA polymerase III C5 subunit K03027 RPAC1; DNA-directed RNA polymerases I and III subunit RPAC1
E cgd4_3200 hypothetical protein K03020 RPAC2; DNA-directed RNA polymerases I and III subunit RPAC2
D Pol III specific subunits
E cgd6_4580 RNA polymerase III C34 subunit; rpc34p ortholog K03025 RPC6; DNA-directed RNA polymerase III subunit RPC6
E cgd1_1960 RPB7 subunit of the RNA polymerase III, OB fold K03022 RPC8; DNA-directed RNA polymerase III subunit RPC8
E cgd7_510 RNA polymerase III subunit C11 K03019 RPC11; DNA-directed RNA polymerase III subunit RPC11
E cgd7_505 hypothetical protein K03019 RPC11; DNA-directed RNA polymerase III subunit RPC11
D Pol I, II, III common subunits
E cgd2_980 DNA-directed RNA polymerase 2 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
E cgd7_4770 DNA-directed RNA polymerase subunit K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
E cgd1_2260 RNA polymerase II B8 subunit K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
E cgd7_3240 transcription activator K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E cgd4_3260 DNA-directed RNA polymerases I, II, and III 8.3 kda polypeptide K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
C Basal transcription factors
D TFIIIA
E cgd2_1150 hypothetical protein K09191 GTF3A; general transcription factor IIIA
D TFIIIB
E cgd8_2030 TATA-box factor binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
E cgd5_3540 cyclin domain protein K15196 BRF1; transcription factor IIIB 90 kDa subunit
E cgd4_1270 transcription factor TFIIIB, SANT domain K15198 BDP1; transcription factor TFIIIB component B''
D TFIIIC
E cgd5_1280 tfc4p like TFIIIC subunit; TPR repeat containing basal transcription factor K15201 GTP3C3; general transcription factor 3C polypeptide 3 (transcription factor C subunit 4)
E cgd2_730 RNA polymerase III transcription factor (TF)IIIC subunit tau/Tfc1p K15202 GTF3C5; general transcription factor 3C polypeptide 5 (transcription factor C subunit 1)
D TFIIIC, fungi type
E cgd2_730 RNA polymerase III transcription factor (TF)IIIC subunit tau/Tfc1p K15202 GTF3C5; general transcription factor 3C polypeptide 5 (transcription factor C subunit 1)
E cgd5_1280 tfc4p like TFIIIC subunit; TPR repeat containing basal transcription factor K15201 GTP3C3; general transcription factor 3C polypeptide 3 (transcription factor C subunit 4)
C Other transcription-related factors
D snRNA-activating protein complex (SNAPc)
E cgd7_1050 hypothetical protein K15210 SNAPC3; snRNA-activating protein complex subunit 3
D Octamer transcription factors
D Others
B RNA polymerase I system
C RNA polymerase I
D Core subunits
E cgd5_730 DNA-directed RNA polymerase I K02999 RPA1; DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6]
E cgd1_2770 RNA polymerase 1 beta subunit K03002 RPA2; DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6]
E cgd8_300 RNA polymerase III C5 subunit K03027 RPAC1; DNA-directed RNA polymerases I and III subunit RPAC1
E cgd4_3200 hypothetical protein K03020 RPAC2; DNA-directed RNA polymerases I and III subunit RPAC2
D Pol I specific subunits
E cgd1_1620 RPB7 like OB fold RNA polymerase subunit K03004 RPA43; DNA-directed RNA polymerase I subunit RPA43
D Pol I, II, III common subunits
E cgd2_980 DNA-directed RNA polymerase 2 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
E cgd7_4770 DNA-directed RNA polymerase subunit K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
E cgd1_2260 RNA polymerase II B8 subunit K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
E cgd7_3240 transcription activator K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E cgd4_3260 DNA-directed RNA polymerases I, II, and III 8.3 kda polypeptide K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
C Basal transcription factors
D SL1/TIF-1B
E cgd8_2030 TATA-box factor binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
C Other transcription-related factors
D UBF
D Transcription initiation factors
E cgd6_2810 hypothetical protein K15216 RRN3; RNA polymerase I-specific transcription initiation factor RRN3
D Transcription elongation factors
E cgd2_2820 transcription factor K15171 SUPT4H1; transcription elongation factor SPT4
E cgd6_4650 5kows transcription initiation protein SPT5 K15172 SUPT5H; transcription elongation factor SPT5
D NoRC (nucleolar remodeling complex)
E cgd6_3860 SNF2 helicase K11654 SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]
D CTDK-I complex
D Transcription termination factors
D Others
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AProkaryotic type
B Bacterial type
C RNA polymerase
D Core subunits
D Sigma factors
C Other transcription-related factors
D RNA polymerase-associated proteins
D Transcription elongation factors
D Transcription termination factor
B Archaeal type
C RNA polymerase
D Core subunits
C Basal transcription factors
D TFB
E cgd8_880 transcription initiation factor TFIIB Sua7p; ZnR+2cyclins K03124 TFIIB; transcription initiation factor TFIIB
D TFE
D TFS
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 9, 2024