+F Repair protein KO
#
DNA Repair and Recombination Proteins - Haliscomenobacter hydrossis
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Halhy_3814 methylated-DNA/protein-cysteinemethyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Halhy_6193 DNA photolyase FAD-binding protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D Halhy_0344 Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E Halhy_1026 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Halhy_3529 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Halhy_1082 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D Halhy_4536 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Halhy_0092 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Halhy_2414 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Halhy_1606 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Halhy_0357 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Halhy_3767 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Halhy_4188 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Halhy_3814 methylated-DNA/protein-cysteinemethyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Halhy_2691 transcriptional regulator, AraC family K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D Halhy_6193 DNA photolyase FAD-binding protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D Halhy_0344 Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D Halhy_1209 deoxyribodipyrimidine photolyase-related protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E Halhy_1026 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Halhy_3801 HhH-GPD family protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E Halhy_3529 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Halhy_2199 DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Halhy_1082 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Halhy_4182 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E Halhy_5989 hypothetical protein K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
D DNA ligase
E Halhy_3948 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E Halhy_3156 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E Halhy_4498 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E Halhy_2588 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E Halhy_3115 UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E Halhy_2136 UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E Halhy_2688 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Halhy_1865 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Halhy_4659 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Halhy_3156 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E Halhy_3948 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F Halhy_4574 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F Halhy_4575 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F Halhy_4768 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F Halhy_3470 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E Halhy_1093 DNA mismatch repair protein mutS K03555 mutS; DNA mismatch repair protein MutS
E Halhy_0351 MutS2 protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E Halhy_3342 DNA mismatch repair protein mutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E Halhy_5122 Exodeoxyribonuclease VII K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E Halhy_5124 Exonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E Halhy_1461 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E Halhy_3376 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E Halhy_0296 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E Halhy_3176 DNA polymerase III gamma/tau subunits-like protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E Halhy_6118 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Halhy_5346 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Halhy_0174 Exonuclease RNase T and DNA polymerase III K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Halhy_3596 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E Halhy_3948 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E Halhy_2688 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Halhy_1865 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Halhy_4659 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Halhy_2957 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E Halhy_0506 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E Halhy_2253 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E Halhy_2575 D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E Halhy_2491 Protein recA K03553 recA; recombination protein RecA
E Halhy_1987 Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E Halhy_6127 Holliday junction ATP-dependent DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Halhy_2084 Crossover junction endodeoxyribonuclease ruvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E Halhy_0381 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E Halhy_6338 SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Halhy_6337 nuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E Halhy_2491 Protein recA K03553 recA; recombination protein RecA
E Halhy_2384 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E Halhy_5563 DNA replication and repair protein recF K03629 recF; DNA replication and repair protein RecF
E Halhy_2822 putative transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Halhy_2390 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Halhy_0148 putative transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Halhy_5025 putative transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Halhy_3642 DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
E Halhy_4265 Recombination protein recR K06187 recR; recombination protein RecR
E Halhy_4514 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E Halhy_1987 Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E Halhy_6127 Holliday junction ATP-dependent DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Halhy_2084 Crossover junction endodeoxyribonuclease ruvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E Halhy_3898 UvrD/REP helicase K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D Other HR factor
E Halhy_6109 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
E Halhy_0479 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
E Halhy_6722 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E Halhy_6338 SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Halhy_6337 nuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
E Halhy_5719 protein of unknown function DUF853 NPT hydrolase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F Halhy_5639 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F Halhy_2737 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F Halhy_5393 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F Halhy_4162 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F Halhy_2595 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F Halhy_3642 DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
F Halhy_4265 Recombination protein recR K06187 recR; recombination protein RecR
F Halhy_3948 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F Halhy_6043 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Halhy_6749 helicase domain-containing protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Halhy_2771 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Halhy_0260 ATP-dependent DNA helicase, RecQ family K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Halhy_4498 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
F Halhy_2588 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
F Halhy_3115 UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D Halhy_5781 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D Halhy_6720 DNA-directed DNA polymerase K03502 umuC; DNA polymerase V
D Halhy_0758 DNA-directed DNA polymerase K03502 umuC; DNA polymerase V
D Halhy_6572 DNA-directed DNA polymerase K03502 umuC; DNA polymerase V
D Halhy_6719 Peptidase S24/S26A/S26B, conserved region K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D Halhy_6570 Peptidase S24/S26A/S26B, conserved region K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D Halhy_0757 Peptidase S24/S26A/S26B, conserved region K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D Halhy_2491 Protein recA K03553 recA; recombination protein RecA
D Halhy_4514 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D Halhy_2957 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D Halhy_0506 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D Halhy_3146 DNA-damage-inducible protein D K14623 dinD; DNA-damage-inducible protein D
D Halhy_6041 regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D Halhy_5396 PHP domain protein K02347 polX; DNA polymerase (family X)
C DNA helicases
C Modulation of nucleotide pools
D Halhy_4536 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Halhy_0092 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Halhy_2414 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Halhy_1606 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Halhy_0357 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Halhy_3767 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Halhy_4188 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Halhy_2334 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C Others
D Halhy_0349 phosphoesterase RecJ domain protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024