+F Chromosome and associated proteins KO
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Chromosome and Associated Proteins - Schizosaccharomyces pombe (fission yeast)
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AEukaryotic type
B Sister chromatid cohesion proteins
C Cohesin complex
D SPBC29A10.04 psm1; mitotic cohesin complex subunit Psm1 K06636 SMC1; structural maintenance of chromosome 1
D SPAC10F6.09c psm3; mitotic cohesin complex subunit Psm3 K06669 SMC3; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
D SPCC338.17c rad21; mitotic cohesin complex non-SMC subunit Rad21 K06670 SCC1; cohesin complex subunit SCC1
D SPAC17H9.20 psc3; mitotic cohesin complex non-SMC subunit Psc3 K06671 STAG1_2; cohesin complex subunit SA-1/2
C Adherin complex
D SPAC31A2.05c mis4; adherin Mis4 K06672 SCC2; cohesin loading factor subunit SCC2
D SPAC110.02 pds5; cohesin-associated protein Pds5 K11267 PDS5; sister chromatid cohesion protein PDS5
C CTF18-RFC complex
D SPBC902.02c ctf18; RFC-like complex subunit Ctf18 K11269 CTF18; chromosome transmission fidelity protein 18
D SPAC19D5.11c ctf8; putative DNA replication factor C complex subunit Ctf8 K11270 CTF8; chromosome transmission fidelity protein 8
D SPAC31A2.15c dcc1; Ctf18 RFC-like complex subunit Dcc1 K11271 DSCC1; sister chromatid cohesion protein DCC1
D SPAC23D3.02 rfc2; DNA replication factor C complex subunit Rfc2 K10755 RFC2_4; replication factor C subunit 2/4
D SPAC1687.03c rfc4; putative DNA replication factor C complex subunit Rfc4 K10755 RFC2_4; replication factor C subunit 2/4
D SPAC27E2.10c rfc3; DNA replication factor C complex subunit Rfc3 K10756 RFC3_5; replication factor C subunit 3/5
D SPBC83.14c rfc5; putative DNA replication factor C complex subunit Rfc5 K10756 RFC3_5; replication factor C subunit 3/5
C Fork protection complex
D SPBC216.06c swi1; replication fork protection complex subunit Swi1 K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D SPBC30D10.04 swi3; replication fork protection complex subunit Swi3 K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D SPAC694.06c mrc1; protein mrc1 K11272 MRC1; mediator of replication checkpoint protein 1
C Other sister chromatid cohesion factors
D SPAC3G6.11 chl1; putative ATP-dependent DNA helicase Chl1 K11273 DDX11; chromosome transmission fidelity protein 1 [EC:5.6.2.7]
D SPAPB1E7.02c mcl1; DNA polymerase alpha accessory factor Mcl1 K11274 WDHD1; chromosome transmission fidelity protein 4
D SPAC15E1.08 naa10; putative NatA N-acetyltransferase complex catalytic subunit Naa10 K20791 NAA10_11; N-alpha-acetyltransferase 10/11 [EC:2.3.1.255]
D SPCC338.07c naa15; putative NatA N-acetyltransferase complex regulatory subunit Naa15 K20792 NAA15_16; N-alpha-acetyltransferase 15/16, NatA auxiliary subunit
D SPBC13E7.02 cwf24; zf-C3HC4 domain-containing and GCN5-like protein cwf24 K20793 NAA50; N-alpha-acetyltransferase 50 [EC:2.3.1.258 2.3.1.309]
B Meiosis-specific proteins
C Cohesin complex and associated proteins
D SPBC29A10.04 psm1; mitotic cohesin complex subunit Psm1 K06636 SMC1; structural maintenance of chromosome 1
D SPAC10F6.09c psm3; mitotic cohesin complex subunit Psm3 K06669 SMC3; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
D SPBC29A10.14 rec8; meiotic cohesin complex subunit Rec8 K12780 REC8; meiotic recombination protein REC8, fungi type
C Synaptonemal complex
C DSB formation-related proteins
D SPCC23B6.03c tel1; ATM checkpoint kinase K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D SPAC17A5.11 rec12; endonuclease Rec12 K10878 SPO11; meiotic recombination protein SPO11
C Others
D SPAC8E11.03c dmc1; RecA family ATPase Dmc1 K10872 DMC1; meiotic recombination protein DMC1
B Nucleosome assembly factors
C Histones
D SPCC622.08c hta1; histone H2A alpha K11251 H2A; histone H2A
D SPAC19G12.06c hta2; histone H2A beta K11251 H2A; histone H2A
D SPBC11B10.10c pht1; histone H2A.Z-like protein Pht1 K11251 H2A; histone H2A
D SPCC622.09 htb1; histone H2B Htb1 K11252 H2B; histone H2B
D SPAC1834.04 hht1; histone H3 h3.1 K11253 H3; histone H3
D SPBC1105.11c hht3; histone H3 h3.3 K11253 H3; histone H3
D SPBC8D2.04 hht2; histone H3 h3.2 K11253 H3; histone H3
D SPAC1834.03c hhf1; histone H4 h4.1 K11254 H4; histone H4
D SPBC1105.12 hhf3; histone H4 h4.3 K11254 H4; histone H4
D SPBC8D2.03c hhf2; histone H4 h4.2 K11254 H4; histone H4
C Histone chaperones
D Nucleoplasmins
D NAPs (Nucleosome assembly proteins)
E SPCC364.06 nap1; nucleosome assembly protein Nap1 K11279 NAP1L1; nucleosome assembly protein 1-like 1
E SPBC2D10.11c nap2; putative nucleosome assembly protein Nap2 K11279 NAP1L1; nucleosome assembly protein 1-like 1
D CAF-1
E SPBC29A10.03c pcf1; CAF assembly factor (CAF-1) complex large subunit Pcf1 K10750 CHAF1A; chromatin assembly factor 1 subunit A
E SPAC26H5.03 pcf2; CAF assembly factor complex subunit B Pcf2 K10751 CHAF1B; chromatin assembly factor 1 subunit B
E SPCC1672.10 mis16; kinetochore protein Mis16 K10752 RBBP4; histone-binding protein RBBP4
E SPAC29A4.18 prw1; Clr6 histone deacetylase complex subunit Prw1 K10752 RBBP4; histone-binding protein RBBP4
E SPAC25H1.06 pcf3; CAF assembly factor complex subunit B Pcf3 K10752 RBBP4; histone-binding protein RBBP4
D FACT complex
E SPBC609.05 pob3; FACT complex component Pob3 K09272 SSRP1; FACT complex subunit SSRP1/POB3
E SPBP8B7.19 spt16; FACT complex component Spt16 K25639 SUPT16H; FACT complex subunit SPT16
D Other Histone chaperones and regulators
E SPCC663.05c cia1; histone chaperone Cia1 K10753 ASF1; histone chaperone ASF1
E SPAC1F7.01c spt6; putative transcription elongation factor Spt6 K11292 SUPT6H; transcription elongation factor SPT6
E SPBC15D4.03 slm9; hira protein Slm9 K11293 HIRA; protein HIRA/HIR1
E SPBC31F10.13c hip1; histone chaperone Hip1 K11293 HIRA; protein HIRA/HIR1
E SPAC140.02 gar2; rRNA-processing protein gar2 K11294 NCL; nucleolin
C HMG (high mobility group) proteins
B Histone modification proteins
C HATs (histone acetyltransferases)
D SPAC139.06 hat1; histone acetyltransferase Hat1 K11303 HAT1; histone acetyltransferase 1 [EC:2.3.1.48]
D SPAC1952.05 gcn5; SAGA complex histone acetyltransferase catalytic subunit Gcn5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
D SPAC2G11.14 taf111; transcription factor TFIID complex subunit Taf111 K23358 TAF1; transcription initiation factor TFIID subunit 1, fungi type [EC:2.3.1.48]
D SPAC637.12c mst1; KAT5 family histone acetyltransferase Mst1 K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
D SPBC342.06c rtt109; RTT109 family histone lysine acetyltransferase K11309 RTT109; regulator of Ty1 transposition protein 109
D SPCC825.04c naa40; putative histone N-acetyltransferase Naa40 K20794 NAA40; N-alpha-acetyltransferase 40 [EC:2.3.1.257]
C HAT complexes
D PCAF complex
E SPAC1952.05 gcn5; SAGA complex histone acetyltransferase catalytic subunit Gcn5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E SPBP16F5.03c tra1; SAGA complex phosphatidylinositol pseudokinase Tra1 K08874 TRRAP; transformation/transcription domain-associated protein
E SPAC1F5.11c tra2; phosphatidylinositol kinase-like protein Tra2 K08874 TRRAP; transformation/transcription domain-associated protein
E SPCC61.02 spt3; SAGA complex subunit Spt3 K11313 SUPT3H; transcription initiation protein SPT3
E SPCC24B10.08c ada2; SAGA complex subunit Ada2 K11314 TADA2A; transcriptional adapter 2-alpha
E SPBC28F2.10c ngg1; SAGA complex subunit Ngg1 K11315 TADA3; transcriptional adapter 3
E SPBC15D4.14 taf73; transcription initiation factor TFIID subunit taf73 K03130 TAF5; transcription initiation factor TFIID subunit 5
E SPCC5E4.03c taf5; transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E SPCC16C4.18c taf6; histone H4-like protein Taf6 K03131 TAF6; transcription initiation factor TFIID subunit 6
E SPAC12G12.05c taf9; SAGA complex/ transcription initiation factor Taf9 K03133 TAF9B; transcription initiation factor TFIID subunit 9B
E SPBC21H7.02 taf10; SAGA complex/transcription factor TFIID complex subunit Taf10 K03134 TAF10; transcription initiation factor TFIID subunit 10
E SPAC15A10.02 taf12; transcription factor TFIID complex subunit A/ SAGA complex subunit K03126 TAF12; transcription initiation factor TFIID subunit 12
D STAGA complex
E SPAC1952.05 gcn5; SAGA complex histone acetyltransferase catalytic subunit Gcn5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E SPBP16F5.03c tra1; SAGA complex phosphatidylinositol pseudokinase Tra1 K08874 TRRAP; transformation/transcription domain-associated protein
E SPAC1F5.11c tra2; phosphatidylinositol kinase-like protein Tra2 K08874 TRRAP; transformation/transcription domain-associated protein
E SPCC61.02 spt3; SAGA complex subunit Spt3 K11313 SUPT3H; transcription initiation protein SPT3
E SPBC28F2.10c ngg1; SAGA complex subunit Ngg1 K11315 TADA3; transcriptional adapter 3
E SPBC15D4.14 taf73; transcription initiation factor TFIID subunit taf73 K03130 TAF5; transcription initiation factor TFIID subunit 5
E SPCC5E4.03c taf5; transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E SPCC16C4.18c taf6; histone H4-like protein Taf6 K03131 TAF6; transcription initiation factor TFIID subunit 6
E SPAC12G12.05c taf9; SAGA complex/ transcription initiation factor Taf9 K03133 TAF9B; transcription initiation factor TFIID subunit 9B
E SPBC21H7.02 taf10; SAGA complex/transcription factor TFIID complex subunit Taf10 K03134 TAF10; transcription initiation factor TFIID subunit 10
E SPAC15A10.02 taf12; transcription factor TFIID complex subunit A/ SAGA complex subunit K03126 TAF12; transcription initiation factor TFIID subunit 12
E SPAPJ698.03c prp12; putative U2 snRNP-associated protein Sap130 K12830 SF3B3; splicing factor 3B subunit 3
D TFTC complex
E SPAC1952.05 gcn5; SAGA complex histone acetyltransferase catalytic subunit Gcn5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E SPBP16F5.03c tra1; SAGA complex phosphatidylinositol pseudokinase Tra1 K08874 TRRAP; transformation/transcription domain-associated protein
E SPAC1F5.11c tra2; phosphatidylinositol kinase-like protein Tra2 K08874 TRRAP; transformation/transcription domain-associated protein
E SPCC61.02 spt3; SAGA complex subunit Spt3 K11313 SUPT3H; transcription initiation protein SPT3
E SPBC28F2.10c ngg1; SAGA complex subunit Ngg1 K11315 TADA3; transcriptional adapter 3
E SPAC3A12.05c taf2; putative TATA-binding protein-associated factor Taf2 K03128 TAF2; transcription initiation factor TFIID subunit 2
E SPBC15D4.14 taf73; transcription initiation factor TFIID subunit taf73 K03130 TAF5; transcription initiation factor TFIID subunit 5
E SPCC5E4.03c taf5; transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E SPCC16C4.18c taf6; histone H4-like protein Taf6 K03131 TAF6; transcription initiation factor TFIID subunit 6
E SPAC13F5.02c ptr6; transcription factor TFIID complex subunit Taf7 K03132 TAF7; transcription initiation factor TFIID subunit 7
E SPAC12G12.05c taf9; SAGA complex/ transcription initiation factor Taf9 K03133 TAF9B; transcription initiation factor TFIID subunit 9B
E SPBC21H7.02 taf10; SAGA complex/transcription factor TFIID complex subunit Taf10 K03134 TAF10; transcription initiation factor TFIID subunit 10
E SPAC15A10.02 taf12; transcription factor TFIID complex subunit A/ SAGA complex subunit K03126 TAF12; transcription initiation factor TFIID subunit 12
E SPAPJ698.03c prp12; putative U2 snRNP-associated protein Sap130 K12830 SF3B3; splicing factor 3B subunit 3
D TIP60 complex
E SPAC637.12c mst1; KAT5 family histone acetyltransferase Mst1 K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
E SPBP16F5.03c tra1; SAGA complex phosphatidylinositol pseudokinase Tra1 K08874 TRRAP; transformation/transcription domain-associated protein
E SPAC1F5.11c tra2; phosphatidylinositol kinase-like protein Tra2 K08874 TRRAP; transformation/transcription domain-associated protein
E SPCC830.05c epl1; NuA4 histone acetyltransferase complex Epl1 K11322 EPC; enhancer of polycomb-like protein
E SPAC9G1.13c swc4; Swr1 complex subunit Swc4 K11324 DMAP1; DNA methyltransferase 1-associated protein 1
E SPAPB8E5.09 rvb1; AAA family ATPase Rvb1 K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
E SPBC83.08 rvb2; AAA family ATPase Rvb2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
E SPAC23H4.12 alp13; MRG family Clr6 histone deacetylase complex subunit Alp13 K11339 MORF4L1; mortality factor 4-like protein 1
E SPAC17G8.07 yaf9; YEATS family histone acetyltransferase subunit Yaf9 K11341 YEATS4; YEATS domain-containing protein 4
E SPAC6F6.09 eaf6; putative NuA4 histone acetyltransferase complex subunit Eaf6 K11344 MEAF6; chromatin modification-related protein EAF6
D HBO1 complex
E SPAC6F6.09 eaf6; putative NuA4 histone acetyltransferase complex subunit Eaf6 K11344 MEAF6; chromatin modification-related protein EAF6
D MOZ/MORF complex
E SPAC6F6.09 eaf6; putative NuA4 histone acetyltransferase complex subunit Eaf6 K11344 MEAF6; chromatin modification-related protein EAF6
D SAGA complex
E SPAC1952.05 gcn5; SAGA complex histone acetyltransferase catalytic subunit Gcn5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E SPBP16F5.03c tra1; SAGA complex phosphatidylinositol pseudokinase Tra1 K08874 TRRAP; transformation/transcription domain-associated protein
E SPAC1F5.11c tra2; phosphatidylinositol kinase-like protein Tra2 K08874 TRRAP; transformation/transcription domain-associated protein
E SPCC61.02 spt3; SAGA complex subunit Spt3 K11313 SUPT3H; transcription initiation protein SPT3
E SPBC25H2.11c spt7; SAGA complex bromodomain subunit Spt7 K11359 SPT7; transcriptional activator SPT7
E SPBC14C8.17c spt8; SAGA complex subunit Spt8 K11360 SPT8; transcriptional activator SPT8
E SPAC4D7.10c spt20; SAGA complex subunit Spt20 K11361 SPT20; transcription factor SPT20
E SPBC887.18c hfi1; SAGA complex subunit Hfi1 K11362 HFI1; transcriptional coactivator HFI1/ADA1
E SPCC24B10.08c ada2; SAGA complex subunit Ada2 K11314 TADA2A; transcriptional adapter 2-alpha
E SPBC28F2.10c ngg1; SAGA complex subunit Ngg1 K11315 TADA3; transcriptional adapter 3
E SPAC57A10.14 sgf11; SAGA complex subunit Sgf11 K11363 SGF11; SAGA-associated factor 11
E SPBC1921.07c sgf29; SAGA complex subunit Sgf29 K11364 SGF29; SAGA-associated factor 29
E SPCC126.04c sgf73; SAGA complex subunit Sgf73 K11365 SGF73; SAGA-associated factor 73
E SPBC15D4.14 taf73; transcription initiation factor TFIID subunit taf73 K03130 TAF5; transcription initiation factor TFIID subunit 5
E SPCC5E4.03c taf5; transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E SPCC16C4.18c taf6; histone H4-like protein Taf6 K03131 TAF6; transcription initiation factor TFIID subunit 6
E SPAC12G12.05c taf9; SAGA complex/ transcription initiation factor Taf9 K03133 TAF9B; transcription initiation factor TFIID subunit 9B
E SPBC21H7.02 taf10; SAGA complex/transcription factor TFIID complex subunit Taf10 K03134 TAF10; transcription initiation factor TFIID subunit 10
E SPAC15A10.02 taf12; transcription factor TFIID complex subunit A/ SAGA complex subunit K03126 TAF12; transcription initiation factor TFIID subunit 12
E SPAC13A11.04c ubp8; SAGA complex ubiquitin Ubp8 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
E SPAC1783.05 hrp1; ATP-dependent DNA helicase Hrp1 K11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]
E SPAC3G6.01 hrp3; ATP-dependent DNA helicase Hrp3 K11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]
E SPBC6B1.12c sus1; SAGA complex subunit Sus1 K11368 ENY2; enhancer of yellow 2 transcription factor
D SLIK complex
E SPAC1952.05 gcn5; SAGA complex histone acetyltransferase catalytic subunit Gcn5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E SPBP16F5.03c tra1; SAGA complex phosphatidylinositol pseudokinase Tra1 K08874 TRRAP; transformation/transcription domain-associated protein
E SPAC1F5.11c tra2; phosphatidylinositol kinase-like protein Tra2 K08874 TRRAP; transformation/transcription domain-associated protein
E SPCC61.02 spt3; SAGA complex subunit Spt3 K11313 SUPT3H; transcription initiation protein SPT3
E SPBC25H2.11c spt7; SAGA complex bromodomain subunit Spt7 K11359 SPT7; transcriptional activator SPT7
E SPAC4D7.10c spt20; SAGA complex subunit Spt20 K11361 SPT20; transcription factor SPT20
E SPBC887.18c hfi1; SAGA complex subunit Hfi1 K11362 HFI1; transcriptional coactivator HFI1/ADA1
E SPCC24B10.08c ada2; SAGA complex subunit Ada2 K11314 TADA2A; transcriptional adapter 2-alpha
E SPBC28F2.10c ngg1; SAGA complex subunit Ngg1 K11315 TADA3; transcriptional adapter 3
E SPAC57A10.14 sgf11; SAGA complex subunit Sgf11 K11363 SGF11; SAGA-associated factor 11
E SPBC1921.07c sgf29; SAGA complex subunit Sgf29 K11364 SGF29; SAGA-associated factor 29
E SPCC126.04c sgf73; SAGA complex subunit Sgf73 K11365 SGF73; SAGA-associated factor 73
E SPBC15D4.14 taf73; transcription initiation factor TFIID subunit taf73 K03130 TAF5; transcription initiation factor TFIID subunit 5
E SPCC5E4.03c taf5; transcription initiation factor TFIID subunit 5 K03130 TAF5; transcription initiation factor TFIID subunit 5
E SPCC16C4.18c taf6; histone H4-like protein Taf6 K03131 TAF6; transcription initiation factor TFIID subunit 6
E SPAC12G12.05c taf9; SAGA complex/ transcription initiation factor Taf9 K03133 TAF9B; transcription initiation factor TFIID subunit 9B
E SPBC21H7.02 taf10; SAGA complex/transcription factor TFIID complex subunit Taf10 K03134 TAF10; transcription initiation factor TFIID subunit 10
E SPAC15A10.02 taf12; transcription factor TFIID complex subunit A/ SAGA complex subunit K03126 TAF12; transcription initiation factor TFIID subunit 12
E SPAC13A11.04c ubp8; SAGA complex ubiquitin Ubp8 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
E SPAC1783.05 hrp1; ATP-dependent DNA helicase Hrp1 K11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]
E SPAC3G6.01 hrp3; ATP-dependent DNA helicase Hrp3 K11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]
D ADA-HAT complex
E SPAC1952.05 gcn5; SAGA complex histone acetyltransferase catalytic subunit Gcn5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E SPCC24B10.08c ada2; SAGA complex subunit Ada2 K11314 TADA2A; transcriptional adapter 2-alpha
E SPBC28F2.10c ngg1; SAGA complex subunit Ngg1 K11315 TADA3; transcriptional adapter 3
E SPBC1921.07c sgf29; SAGA complex subunit Sgf29 K11364 SGF29; SAGA-associated factor 29
D HAT-A2 complex
E SPAC1952.05 gcn5; SAGA complex histone acetyltransferase catalytic subunit Gcn5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E SPCC24B10.08c ada2; SAGA complex subunit Ada2 K11314 TADA2A; transcriptional adapter 2-alpha
E SPBC28F2.10c ngg1; SAGA complex subunit Ngg1 K11315 TADA3; transcriptional adapter 3
D ATAC complex
E SPAC1952.05 gcn5; SAGA complex histone acetyltransferase catalytic subunit Gcn5 K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
E SPCC24B10.08c ada2; SAGA complex subunit Ada2 K11314 TADA2A; transcriptional adapter 2-alpha
E SPBC28F2.10c ngg1; SAGA complex subunit Ngg1 K11315 TADA3; transcriptional adapter 3
E SPBC1921.07c sgf29; SAGA complex subunit Sgf29 K11364 SGF29; SAGA-associated factor 29
E SPBC30D10.02 putative transcription corepressor K21751 DR1; down-regulator of transcription 1
E SPBC354.03 swd3; WD repeat protein Swd3 K14963 WDR5; COMPASS component SWD3
D HATB complex
E SPAC139.06 hat1; histone acetyltransferase Hat1 K11303 HAT1; histone acetyltransferase 1 [EC:2.3.1.48]
E SPCC1672.10 mis16; kinetochore protein Mis16 K10752 RBBP4; histone-binding protein RBBP4
E SPAC29A4.18 prw1; Clr6 histone deacetylase complex subunit Prw1 K10752 RBBP4; histone-binding protein RBBP4
E SPAC25H1.06 pcf3; CAF assembly factor complex subunit B Pcf3 K10752 RBBP4; histone-binding protein RBBP4
E SPBC577.15c sim3; NASP family CENP-A chaperone K11372 HIF1; HAT1-interacting factor 1
D NSL complex
E SPBC354.03 swd3; WD repeat protein Swd3 K14963 WDR5; COMPASS component SWD3
D MSL complex
D NuA3 complex
E SPAC17G8.13c mst2; histone acetyltransferase Mst2 K11378 SAS3; histone acetyltransferase SAS3 [EC:2.3.1.48]
E SPAC22H12.02 tfg3; transcription factor TFIIF complex subunit Tfg3 K03140 TAF14; transcription initiation factor TFIID/TFIIF subunit
D NuA4 complex
E SPAC637.12c mst1; KAT5 family histone acetyltransferase Mst1 K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
E SPBP16F5.03c tra1; SAGA complex phosphatidylinositol pseudokinase Tra1 K08874 TRRAP; transformation/transcription domain-associated protein
E SPAC1F5.11c tra2; phosphatidylinositol kinase-like protein Tra2 K08874 TRRAP; transformation/transcription domain-associated protein
E SPAC3G9.08 png1; chromatin modification-related protein K11396 YNG2; chromatin modification-related protein YNG2
E SPAC17G8.07 yaf9; YEATS family histone acetyltransferase subunit Yaf9 K11341 YEATS4; YEATS domain-containing protein 4
E SPCC1795.08c vid21; NuA4 histone acetyltransferase complex subunit Vid21 K11397 EAF1; chromatin modification-related protein VID21
E SPAC9G1.13c swc4; Swr1 complex subunit Swc4 K11324 DMAP1; DNA methyltransferase 1-associated protein 1
E SPAC23H4.12 alp13; MRG family Clr6 histone deacetylase complex subunit Alp13 K11339 MORF4L1; mortality factor 4-like protein 1
E SPAC6F6.09 eaf6; putative NuA4 histone acetyltransferase complex subunit Eaf6 K11344 MEAF6; chromatin modification-related protein EAF6
E SPCC830.05c epl1; NuA4 histone acetyltransferase complex Epl1 K11322 EPC; enhancer of polycomb-like protein
E SPBP23A10.08 alp5; actin-like protein Arp4 K11400 ARP4; actin-related protein 4
E SPAC23D3.09 arp42; SWI/SNF and RSC complex subunit Arp42 K11400 ARP4; actin-related protein 4
D SAS complex
C HDACs (histone deacetylases)
D Class I HDACs
E SPBC36.05c clr6; class 1 histone deacetylase Clr6 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E SPAC3G9.07c hos2; class 1 histone deacetylase Hos2 K11483 HOS2; histone deacetylase HOS2 [EC:3.5.1.98]
D Class II HDACs
E SPBC800.03 clr3; class 2 histone deacetylase Clr3 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
D SIRTs (sirtuins, class III HDACs)
D Class IV HDACs
C HDAC complexes
D Sin3A-HDAC complex
E SPBC36.05c clr6; class 1 histone deacetylase Clr6 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
E SPBC12C2.10c pst1; Clr6 histone deacetylase complex subunit Pst1 K11644 SIN3A; paired amphipathic helix protein Sin3a
E SPCC1672.10 mis16; kinetochore protein Mis16 K10752 RBBP4; histone-binding protein RBBP4
E SPAC29A4.18 prw1; Clr6 histone deacetylase complex subunit Prw1 K10752 RBBP4; histone-binding protein RBBP4
E SPAC25H1.06 pcf3; CAF assembly factor complex subunit B Pcf3 K10752 RBBP4; histone-binding protein RBBP4
E SPCC126.13c putative SAP128 family histone deacetylase complex subunit K14324 SAP18; histone deacetylase complex subunit SAP18
D BRAF-HDAC complex
E SPBC36.05c clr6; class 1 histone deacetylase Clr6 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D REST complex
E SPBC12C2.10c pst1; Clr6 histone deacetylase complex subunit Pst1 K11644 SIN3A; paired amphipathic helix protein Sin3a
E SPBC36.05c clr6; class 1 histone deacetylase Clr6 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D SHIP complex
E SPBC36.05c clr6; class 1 histone deacetylase Clr6 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D MiDAC complex
E SPBC36.05c clr6; class 1 histone deacetylase Clr6 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D SMART complex
E SPCC1235.09 hif2; Set3 complex subunit Hif2 K04508 TBL1; transducin (beta)-like 1
D Other HDAC associated proteins
E SPAC2F7.07c cph2; Clr6 histone deacetylase-associated PHD protein-2 Cph2 K26244 PHF12; transcriptional regulatory protein PHF12/RCO1
E SPBC1709.11c png2; chromatin modification family protein Png2 K26245 PHO23; transcriptional regulatory protein PHO23
C HMTs (histone methyltransferases)
D HKMTs (histone lysine methyltransferases)
E SPCC306.04c set1; histone lysine methyltransferase Set1 K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
E SPAC688.14 set13; ribosome L32 lysine methyltransferase Set13 K05302 SETD6; N-lysine methyltransferase SETD6 [EC:2.1.1.-]
E SPAC29B12.02c set2; histone lysine methyltransferase Set2 K23700 SET2; [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359]
E SPCC4B3.12 set9; histone lysine methyltransferase Set9 K24407 SET9; [histone H4]-lysine20 N-trimethyltransferase [EC:2.1.1.372]
E SPBC428.08c clr4; histone H3 methyltransferase Clr4 K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
D PRMTs (protein arginine metyltransferases)
E SPAC890.07c rmt1; protein arginine N-methyltransferase Rmt1 K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
E SPBC8D2.10c rmt3; ribosomal protein arginine N-methyltransferase Rmt3 K11436 PRMT3; type I protein arginine methyltransferase [EC:2.1.1.319]
E SPBC16H5.11c skb1; protein arginine N-methyltransferase Skb1 K02516 PRMT5; type II protein arginine methyltransferase [EC:2.1.1.320]
E SPAC26A3.17c putative N-methyltransferase K18477 RMT2; type IV protein arginine methyltransferase [EC:2.1.1.322]
C HMT complexes
D COMPASS/SET1 complex
E SPCC306.04c set1; histone lysine methyltransferase Set1 K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
E SPCC594.05c spf1; Set1C PHD Finger protein Spf1 K14960 CXXC1; COMPASS component SPP1
E SPAC23H3.05c swd1; Set1C complex subunit Swd1 K14961 RBBP5; COMPASS component SWD1
E SPBC18H10.06c swd2; Set1C complex subunit Swd2.1 K14962 WDR82; COMPASS component SWD2
E SPBC354.03 swd3; WD repeat protein Swd3 K14963 WDR5; COMPASS component SWD3
D COMPASS/SET1 complex (yeast)
E SPCC306.04c set1; histone lysine methyltransferase Set1 K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
E SPCC594.05c spf1; Set1C PHD Finger protein Spf1 K14960 CXXC1; COMPASS component SPP1
E SPAC23H3.05c swd1; Set1C complex subunit Swd1 K14961 RBBP5; COMPASS component SWD1
E SPBC18H10.06c swd2; Set1C complex subunit Swd2.1 K14962 WDR82; COMPASS component SWD2
E SPBC354.03 swd3; WD repeat protein Swd3 K14963 WDR5; COMPASS component SWD3
E SPBC13G1.08c ash2; Ash2-trithorax family protein K14967 BRE2; COMPASS component BRE2
E SPCC18.11c sdc1; Dpy-30 domain protein Sdc1 K14968 CPS25; COMPASS component SDC1
D MLL-HCF complex
E SPAC23H3.05c swd1; Set1C complex subunit Swd1 K14961 RBBP5; COMPASS component SWD1
E SPBC354.03 swd3; WD repeat protein Swd3 K14963 WDR5; COMPASS component SWD3
D MLL3/MLL4 complex
E SPAC23H3.05c swd1; Set1C complex subunit Swd1 K14961 RBBP5; COMPASS component SWD1
E SPBC354.03 swd3; WD repeat protein Swd3 K14963 WDR5; COMPASS component SWD3
D Dot1-containing complex
C Histone demethylases
D SPCC622.16c epe1; Jmjc domain-containing protein Epe1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
C Polycomb repressive complex (PRC) and associated proteins
D Canonical PRC1 (PRC1.2/1.4)
E PRC1.4 specific proteins
D Noncanonical PRC1 (PRC1.1)
E SPCC622.16c epe1; Jmjc domain-containing protein Epe1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E SPBC409.05 skp1; SCF ubiquitin ligase complex subunit Skp1 K03094 SKP1; S-phase kinase-associated protein 1
D Noncanonical PRC1 (PRC1.3/1.5)
E SPAC1851.03 ckb1; CK2 family regulatory subunit Ckb1 K03115 CSNK2B; casein kinase II subunit beta
E SPBC2G5.02c putative CK2 family regulatory subunit protein K03115 CSNK2B; casein kinase II subunit beta
E SPBC17D11.08 WD repeat-containing protein K11805 DCAF7; DDB1- and CUL4-associated factor 7
D Noncanonical PRC1 (PRC1.6)
E SPBC354.03 swd3; WD repeat protein Swd3 K14963 WDR5; COMPASS component SWD3
E SPBC36.05c clr6; class 1 histone deacetylase Clr6 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D PRC2.1
E SPCC1672.10 mis16; kinetochore protein Mis16 K10752 RBBP4; histone-binding protein RBBP4
E SPAC29A4.18 prw1; Clr6 histone deacetylase complex subunit Prw1 K10752 RBBP4; histone-binding protein RBBP4
E SPAC25H1.06 pcf3; CAF assembly factor complex subunit B Pcf3 K10752 RBBP4; histone-binding protein RBBP4
D PRC2.2
E SPCC1672.10 mis16; kinetochore protein Mis16 K10752 RBBP4; histone-binding protein RBBP4
E SPAC29A4.18 prw1; Clr6 histone deacetylase complex subunit Prw1 K10752 RBBP4; histone-binding protein RBBP4
E SPAC25H1.06 pcf3; CAF assembly factor complex subunit B Pcf3 K10752 RBBP4; histone-binding protein RBBP4
D PR-DUB complex
D Other PRC associated proteins
C Sir proteins
D SPBC16D10.07c sir2; Sir2 family histone deacetylase Sir2 K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
D SPCC132.02 hst2; Sir2 family histone deacetylase Hst2 K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
D SPAC1783.04c hst4; Sir2 family histone deacetylase Hst4 K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
C Other histone modification proteins
D SPBC1861.04c putative RNA-binding protein Prp24 K22611 SART3; squamous cell carcinoma antigen recognized by T-cells 3
D SPAC19B12.02c gas1; putative 1,3-beta-glucanosyltransferase Gas1 K22832 GAS1; 1,3-beta-glucanosyltransferase GAS1 [EC:2.4.1.-]
D SPAC11E3.13c gas5; putative 1,3-beta-glucanosyltransferase Gas5 K22836 GAS5; 1,3-beta-glucanosyltransferase GAS5 [EC:2.4.1.-]
D SPAC343.17c WD repeat-containing protein K24752 WDR70; WD repeat-containing protein 70
B Chromosome condensation proteins
C Condensin I
D SPBP4H10.06c cut14; condensin complex subunit Cut14 K06674 SMC2; structural maintenance of chromosome 2
D SPBC146.03c cut3; condensin complex subunit Cut3 K06675 SMC4; structural maintenance of chromosome 4
D SPCC306.03c cnd2; condensin complex non-SMC subunit Cnd2 K06676 BRRN1; condensin complex subunit 2
D SPBC776.13 cnd1; condensin complex non-SMC subunit Cnd1 K06677 YCS4; condensin complex subunit 1
D SPCC188.03 cnd3; condensin complex non-SMC subunit Cnd3 K06678 YCG1; condensin complex subunit 3
C Condensin II
D SPBP4H10.06c cut14; condensin complex subunit Cut14 K06674 SMC2; structural maintenance of chromosome 2
D SPBC146.03c cut3; condensin complex subunit Cut3 K06675 SMC4; structural maintenance of chromosome 4
C Other regulators of chromosome condensation
D SPBC1A4.03c top2; DNA topoisomerase II K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
D SPBC557.03c pim1; Ran GDP/GTP exchange factor K11493 RCC1; regulator of chromosome condensation
B Centromeric chromatin formation proteins
C Kinetochore proteins
D Centromere proteins
E SPBC1105.17 cnp1; centromere-specific histone H3 CENP-A K11495 CENPA; histone H3-like centromeric protein A
E SPBC1861.01c cnp3; centromere protein K11497 CENPC; centromere protein C
E SPBC1604.20c tea2; kinesin-like protein Tea2 K11498 CENPE; centromeric protein E
E SPAC1687.20c mis6; centromere connector protein mis6 K11501 CENPI; centromere protein I
E SPAC4F10.12 fta1; kinetochore protein fta1 K11504 CENPL; centromere protein L
E SPAC17G8.15 new1; histone-fold domain-containing protein K26091 CENPW; centromere protein W
D CPC (chromosomal passenger complex)
D KMN network proteins
E MIS12 complex
E NDC80 complex
F SPBC11C11.03 ndc80; protein Ndc80 K11547 NDC80; kinetochore protein NDC80
F SPAC27F1.04c nuf2; protein Nuf2 K11548 NUF2; kinetochore protein Nuf2
D Mis6 complex
E SPAC1687.20c mis6; centromere connector protein mis6 K11501 CENPI; centromere protein I
E SPBC1861.01c cnp3; centromere protein K11497 CENPC; centromere protein C
E SPBP22H7.09c mis15; kinetochore protein Mis15 K11551 MIS15; central kinetochore subunit Mis15/CHL4
E SPAC25B8.14 mal2; kinetochore protein mal2 K11552 MAL2; central kinetochore subunit Mal2/MCM21
E SPAC16A10.05c dad1; DASH complex subunit Dad1 K11553 DAD1; DASH complex subunit DAD1
E SPAC23H4.11c cnl2; centromere localized protein Cnl2 K11696 CNL2; centromere-localized protein 2
E SPCC1235.07 fta7; kinetochore protein fta7 K11697 FTA7; kinetochore protein Fta7
E SPBC18E5.03c sim4; kinetochore protein sim4 K11698 SIM4; centromere protein Sim4
D COMA complex
E SPAC25B8.14 mal2; kinetochore protein mal2 K11552 MAL2; central kinetochore subunit Mal2/MCM21
D NMS complex
E NDC80 complex
F SPBC11C11.03 ndc80; protein Ndc80 K11547 NDC80; kinetochore protein NDC80
F SPAC27F1.04c nuf2; protein Nuf2 K11548 NUF2; kinetochore protein Nuf2
F SPBC336.08 spc24; protein Spc24 K11557 SPC24; kinetochore protein Spc24, fungi type
F SPCC188.04c spc25; kinetochore protein Spc25 K11558 SPC25; kinetochore protein Spc25, fungi type
E MIND kinetochore complex
F SPBC409.04c mis12; kinetochore protein Mis12 K11559 mis12; kinetochore protein Mis12/MTW1
F SPBC409.09c mis13; kinetochore protein Mis13 K11560 mis13; kinetochore protein Mis13/DSN1
F SPAC688.02c mis14; kinetochore protein Mis14 K11561 mis14; kinetochor protein Mis14/NSL1
F SPAC29E6.04 nnf1; kinetochore protein Nnf1 K11562 NNF1; kinetochore protein NNF1
E SPCC1020.02 spc7; kinetochore protein Spc7 K11563 SPC7; kinetochore protein Spc7/SPC105
D MIS16-MIS18 complex
E SPCC1672.10 mis16; kinetochore protein Mis16 K10752 RBBP4; histone-binding protein RBBP4
E SPAC29A4.18 prw1; Clr6 histone deacetylase complex subunit Prw1 K10752 RBBP4; histone-binding protein RBBP4
E SPAC25H1.06 pcf3; CAF assembly factor complex subunit B Pcf3 K10752 RBBP4; histone-binding protein RBBP4
E SPCC970.12 mis18; kinetochore protein Mis18 K11564 MIS18; kinetochore protein Mis18
D DASH complex
E SPBC27.02c ask1; DASH complex subunit Ask1 K11566 ASK1; DASH complex subunit ASK1
E SPAC16A10.05c dad1; DASH complex subunit Dad1 K11553 DAD1; DASH complex subunit DAD1
E SPAC1805.07c dad2; DASH complex subunit Dad2 K11567 DAD2; DASH complex subunit DAD2
E SPAC14C4.16 dad3; DASH complex subunit Dad3 K11568 DAD3; DASH complex subunit DAD3
E SPBC3B9.22c dad4; DASH complex subunit Dad4 K11569 DAD4; DASH complex subunit DAD4
E SPAC589.08c dam1; DASH complex subunit Dam1 K02307 DAM1; DASH complex subunit DAM1
E SPCC1223.15c spc19; DASH complex subunit Spc19 K11572 SPC19; DASH complex subunit SPC19
D CBF3 complex
E SPBC409.05 skp1; SCF ubiquitin ligase complex subunit Skp1 K03094 SKP1; S-phase kinase-associated protein 1
D Others
C SAC (spindle assembly checkpoint) factors
D Core SAC proteins
E SPBC3D6.04c mad1; mitotic spindle checkpoint protein Mad1 K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
E SPBC20F10.06 mad2; spindle checkpoint protein Mad2 K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
E SPBC12D12.09 rev7; putative DNA polymerase zeta Rev7 K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
E SPCC1322.12c bub1; serine/threonine protein kinase Bub1 K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
E SPAC23H3.08c bub3; mitotic spindle checkpoint protein Bub3 K02180 BUB3; cell cycle arrest protein BUB3
D Motor proteins
E SPBC1604.20c tea2; kinesin-like protein Tea2 K11498 CENPE; centromeric protein E
E RZZ complex
E Dynein complex
F SPAC1093.06c dhc1; dynein heavy chain Dhc1 K10413 DYNC1H; dynein cytoplasmic 1 heavy chain
F SPBC646.17c dic1; dynein intermediate chain Dic1 K10415 DYNC1I; dynein cytoplasmic 1 intermediate chain
D Protein kinases
E SPBC106.01 mph1; dual-specificity protein kinase Mph1 K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
E SPAC31G5.09c spk1; MAP kinase Spk1 K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
E SPAC19E9.02 fin1; NIMA-like serine/threonine protein kinase Fin1 K20872 NEK2; serine/threonine-protein kinase Nek2 [EC:2.7.11.1]
D Others
C Other centromeric chromatin formation proteins
D Shugoshin
D PP2A (protein phosphatase 2A)
E SPAC823.15 ppa1; minor serine/threonine protein phosphatase Ppa1 K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E SPBC16H5.07c ppa2; serine/threonine protein phosphatase Ppa2 K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E SPAP8A3.09c paa1; protein phosphatase regulatory subunit Paa1 K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E SPAC227.07c pab1; protein phosphatase regulatory subunit Pab1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E SPCC188.02 par1; protein phosphatase regulatory subunit Par1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E SPAC6F12.12 par2; protein phosphatase regulatory subunit Par2 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
B Heterochromatin formation proteins
C HP1 (heterochromatin protein 1)
C MBPs (metylated DNA binding proteins)
C Other heterochromatin formation proteins
D SPBC36.05c clr6; class 1 histone deacetylase Clr6 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D SPBC12C2.10c pst1; Clr6 histone deacetylase complex subunit Pst1 K11644 SIN3A; paired amphipathic helix protein Sin3a
D SPCC1672.10 mis16; kinetochore protein Mis16 K10752 RBBP4; histone-binding protein RBBP4
D SPAC29A4.18 prw1; Clr6 histone deacetylase complex subunit Prw1 K10752 RBBP4; histone-binding protein RBBP4
D SPAC25H1.06 pcf3; CAF assembly factor complex subunit B Pcf3 K10752 RBBP4; histone-binding protein RBBP4
D SPBC428.08c clr4; histone H3 methyltransferase Clr4 K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
B Gene silencing
C RISC (RNA-induced silencing complex)
D SPCC188.13c dcr1; dicer K11592 DICER1; endoribonuclease Dicer [EC:3.1.26.-]
D SPCC736.11 ago1; argonaute K11593 ELF2C; eukaryotic translation initiation factor 2C
D SPCC1795.11 sum3; ATP-dependent RNA helicase Sum3 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
C piRNA pathway
D SPAC17A5.14 exo2; exonuclease II Exo2 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
D SPBC776.09 ste13; ATP-dependent RNA helicase Ste13 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
D SPBC336.05c putative S-adenosylmethionine-dependent methyltransferase K20798 HENMT1; small RNA 2'-O-methyltransferase [EC:2.1.1.386]
C RNA interference (RNAi) pathway
D RITS (RNA-induced transcriptional silencing) complex
E SPAC18G6.02c chp1; chromodomain protein Chp1 K11595 CHP1; chromo domain-containing protein 1
E SPCC736.11 ago1; argonaute K11593 ELF2C; eukaryotic translation initiation factor 2C
E SPBC83.03c tas3; RITS complex subunit 3 K11597 TAS3; RNA-induced transcriptional silencing complex protein Tas3
D RDRC (RNA-directed RNA polymerase complex)
E SPAC6F12.09 rdp1; RNA-directed RNA polymerase Rdp1 K11699 RDR; RNA-dependent RNA polymerase [EC:2.7.7.48]
E SPCC663.12 cid12; poly(A) polymerase Cid12 K11700 CID12; poly(A) RNA polymerase Cid12 [EC:2.7.7.19]
E SPCC1739.03 hrr1; helicase Hrr1 K11701 HRR1; helicase required for RNAi-mediated heterochromatin assembly 1 [EC:5.6.2.5]
D Other RNAi proteins
E SPBC30B4.08 eri1; double-strand siRNA ribonuclease Eri1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
C microRNA pathway
D Microprocessor complex
E SPBC119.11c pac1; double-strand-specific ribonuclease Pac1 K03685 rnc; ribonuclease III [EC:3.1.26.3]
D RISC loading complex
E SPCC188.13c dcr1; dicer K11592 DICER1; endoribonuclease Dicer [EC:3.1.26.-]
E SPCC736.11 ago1; argonaute K11593 ELF2C; eukaryotic translation initiation factor 2C
D Other miRNA pathway proteins
E SPAC328.01c putative karyopherin K14289 XPO5; exportin-5
C Transposable elements
B Centrosome formation proteins
C Centriole proteins
D SPCC1682.04 cdc31; centrin K16466 CETN3; centrin-3
D SPBC1A4.03c top2; DNA topoisomerase II K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C Pericentriolar materials (PCM)
D Centriolar satellite
D Other PCM proteins
C Cyclins
C Kinases and associated factors
D SPAC23C4.03 hrk1; haspin-like kinase Hrk1 K16315 GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
D SPBC8D2.01 gsk31; putative serine/threonine protein kinase Gsk31 K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
D SPAC1687.15 gsk3; serine/threonine protein kinase Gsk3 K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
D SPBC106.10 pka1; cAMP-dependent protein kinase catalytic subunit Pka1 K04345 PKA; protein kinase A [EC:2.7.11.11]
D Kinase anchoring protein
C Microtubules and associated factors
D gamma-tubulin ring complex
E SPBC32F12.04 gtb1; gamma-tubulin K10389 TUBG; tubulin gamma
E SPBC365.15 alp4; gamma tubulin complex Spc97/GCP2 subunit Alp4 K16569 TUBGCP2; gamma-tubulin complex component 2
E SPBC428.20c alp6; gamma tubulin complex Spc98/GCP3 subunit Alp6 K16570 TUBGCP3; gamma-tubulin complex component 3
D Other tubulins
E SPBC16A3.15c nda2; tubulin alpha 1 K07374 TUBA; tubulin alpha
E SPBC800.05c atb2; tubulin alpha 2 K07374 TUBA; tubulin alpha
E SPBC26H8.07c nda3; tubulin beta Nda3 K07375 TUBB; tubulin beta
D Dynactin complex
E SPBC1347.12 arp1; putative centractin family actin-like protein Arp1 K16575 ACTR1; centractin
D BRISC complex
D Microtubule-associated proteins
E SPAC3G9.12 peg1; CLASP family microtubule-associated protein K16578 CLASP1_2; CLIP-associating protein 1/2
E SPAC18G6.15 mal3; EB1 family Mal3 K10436 MAPRE; microtubule-associated protein, RP/EB family
C Augmin complex
C Centrosome duplication proteins
D Centriole replication proteins
E SPAC29A4.05 cam2; myosin I light chain Cam2 K02183 CALM; calmodulin
E SPAC3A12.14 cam1; calmodulin Cam1 K02183 CALM; calmodulin
D Regulators of centriole replication
E SPAC27E2.03c putative Obg-Like ATPase K19788 OLA1; obg-like ATPase 1
E SPAC29E6.01 pof11; F-box protein Pof11 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E SPBC1289.03c spi1; Ran GTPase Spi1 K07936 RAN; GTP-binding nuclear protein Ran
E SPAC1805.17 crm1; importin family nuclear export receptor Crm1 K14290 XPO1; exportin-1
D Other centrosome duplication proteins
E SPBC428.18 cdt1; replication licensing factor Cdt1 K10727 CDT1; chromatin licensing and DNA replication factor 1
E SPBC31F10.11c cwf4; protein Cwf4 K12869 CRN; crooked neck
E SPAC1B2.05 mcm5; MCM complex subunit Mcm5 K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
E SPBC29A10.15 orc1; origin recognition complex subunit Orc1 K02603 ORC1; origin recognition complex subunit 1
E SPBC685.09 orc2; origin recognition complex subunit Orc2 K02604 ORC2; origin recognition complex subunit 2
E SPAC3H1.01c orc3; putative origin recognition complex subunit Orp3 K02605 ORC3; origin recognition complex subunit 3
E SPAPB1A10.09 ase1; antiparallel microtubule cross-linking factor Ase1 K16732 PRC1; Ase1/PRC1/MAP65 family protein
C Nde1-Su48 complex
C LINC complex
C 3M complex
C Other centriole associated proteins
D SPAC22F3.05c alp41; ADP-ribosylation factor Alp41 K07943 ARL2; ADP-ribosylation factor-like protein 2
D SPAC110.03 cdc42; Rho family GTPase Cdc42 K04393 CDC42; cell division control protein 42
D SPBC106.20 exo70; putative exocyst complex subunit Exo70 K07195 EXOC7; exocyst complex component 7
D SPBC4.04c mcm2; MCM complex subunit Mcm2 K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D SPCC1682.02c mcm3; MCM complex subunit Mcm3 K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D SPAC9E9.07c ypt2; GTPase Ypt2 K07901 RAB8A; Ras-related protein Rab-8A
D SPBC32H8.09 WD repeat-containing protein K25164 WRAP73; WD repeat-containing protein WRAP73
D SPBC947.01 AAA family ATPase K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
D SPAC328.04 AAA domain-containing protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
D SPBC8D2.16c uncharacterized protein K09142 SPOUT1; methyltransferase [EC:2.1.1.-]
C Spindle formation proteins
D SPBC30B4.05 kap109; karyopherin Kap109 K18423 CSE1; exportin-2 (importin alpha re-exporter)
D SPAC25G10.07c cut7; kinesin-like protein Cut7 K10398 KIF11; kinesin family member 11
D SPAC664.10 klp2; kinesin-like protein Klp2 K10405 KIFC1; kinesin family member C1
D SPAC3A11.14c pkl1; kinesin-like protein Pkl1 K10405 KIFC1; kinesin family member C1
D SPCC962.03c cut15; karyopherin Cut15 K15042 KPNA5_6; importin subunit alpha-6/7
D SPAC1B1.03c kap95; karyopherin Kap95 K14293 KPNB1; importin subunit beta-1
D SPBC17G9.04c nup85; nucleoporin Nup85 K14304 NUP85; nuclear pore complex protein Nup85
D SPAC1486.05 nup189; nucleoporin Nup98 and Nup96 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
D SPBC428.01c nup107; nucleoporin Nup107 K14301 NUP107; nuclear pore complex protein Nup107
D SPAC1805.04 nup132; nucleoporin Nup132 K14300 NUP133; nuclear pore complex protein Nup133
D SPCC290.03c nup186; nucleoporin Nup186 K14310 NUP205; nuclear pore complex protein Nup205
D SPBC1539.04 tts1; tetra-spanning protein 1 K20724 TMEM33; transmembrane protein 33
D SPBC16A3.05c rae1; nucleoporin Rae1 K14298 RAE1; mRNA export factor
D SPBC1289.03c spi1; Ran GTPase Spi1 K07936 RAN; GTP-binding nuclear protein Ran
D SPCC895.07 alp14; microtubule polymerase alp14 K24394 STU2; protein STU2
B Sister chromatid separation proteins
C Securin and associated proteins
C Separase
D SPCC5E4.04 cut1; separase/separin K02365 ESP1; separase [EC:3.4.22.49]
C APC/C complex
D SPBC106.09 cut4; anaphase-promoting complex subunit Apc1 K03348 APC1; anaphase-promoting complex subunit 1
D SPBP23A10.04 apc2; anaphase-promoting complex cullin family subunit Apc2 K03349 APC2; anaphase-promoting complex subunit 2
D SPAC17C9.01c nuc2; anaphase-promoting complex subunit Apc3 K03350 APC3; anaphase-promoting complex subunit 3
D SPAC19G12.01c cut20; anaphase-promoting complex subunit Apc4 K03351 APC4; anaphase-promoting complex subunit 4
D SPAC959.09c apc5; anaphase-promoting complex subunit Apc5 K03352 APC5; anaphase-promoting complex subunit 5
D SPAC6F12.15c cut9; anaphase-promoting complex subunit Cut9 K03353 APC6; anaphase-promoting complex subunit 6
D SPAC6F12.14 cut23; anaphase-promoting complex subunit Apc8 K03355 APC8; anaphase-promoting complex subunit 8
D SPBC1A4.01 apc10; anaphase-promoting complex subunit Apc10 K03357 APC10; anaphase-promoting complex subunit 10
D SPAC343.03 apc11; anaphase-promoting complex subunit Apc11 K03358 APC11; anaphase-promoting complex subunit 11
D SPAC821.08c slp1; WD repeat-containing protein K03363 CDC20; cell division cycle 20, cofactor of APC complex
C Aurora kinases
D SPCC320.13c ark1; aurora-B kinase Ark1 K08850 AURKX; aurora kinase, other [EC:2.7.11.1]
D Regulators of Aurora kinases
E SPBC1604.14c shk1; PAK-like kinase Shk1 K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
C TACC proteins
C Polo kinases
C Early mitotic inhibitors
B Chromatin remodeling factors
C BAF complex
D SPAC2F7.08c snf5; SWI/SNF complex subunit Snf5 K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
D SPAC17G6.10 ssr1; SWI/SNF and RSC complex subunit Ssr1 K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D SPAC23H3.10 ssr2; SWI/SNF and RSC complex subunit Ssr2 K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D SPAC23G3.10c ssr3; SWI/SNF and RSC complex subunit Ssr3 K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
C PBAF complex
D SPAC2F7.08c snf5; SWI/SNF complex subunit Snf5 K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
D SPAC17G6.10 ssr1; SWI/SNF and RSC complex subunit Ssr1 K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D SPAC23H3.10 ssr2; SWI/SNF and RSC complex subunit Ssr2 K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D SPAC23G3.10c ssr3; SWI/SNF and RSC complex subunit Ssr3 K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
C GBAF(ncBAF) complex
D SPAC17G6.10 ssr1; SWI/SNF and RSC complex subunit Ssr1 K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D SPAC23H3.10 ssr2; SWI/SNF and RSC complex subunit Ssr2 K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
D SPAC23G3.10c ssr3; SWI/SNF and RSC complex subunit Ssr3 K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
C CHRAC complex
D SPBC3D6.09 dpb4; DNA polymerase epsilon subunit Dpb4 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
C RSF complex
C WICH complex
C B-WICH complex
D SPCP25A2.02c rhp26; SNF2 family helicase Rhp26 K10841 ERCC6; DNA excision repair protein ERCC-6
D SPBC146.13c myo1; myosin I myo1 K10356 MYO1; myosin I
D SPBC14C8.14c pol5; DNA polymerase phi K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
D SPAC27F1.09c prp10; U2 snRNP-associated protein Sap155 K12828 SF3B1; splicing factor 3B subunit 1
C NORC complex
C BRF complex
C NuRD complex
D SPBC36.05c clr6; class 1 histone deacetylase Clr6 K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
D SPCC1672.10 mis16; kinetochore protein Mis16 K10752 RBBP4; histone-binding protein RBBP4
D SPAC29A4.18 prw1; Clr6 histone deacetylase complex subunit Prw1 K10752 RBBP4; histone-binding protein RBBP4
D SPAC25H1.06 pcf3; CAF assembly factor complex subunit B Pcf3 K10752 RBBP4; histone-binding protein RBBP4
C NuRF complex
D SPCC1672.10 mis16; kinetochore protein Mis16 K10752 RBBP4; histone-binding protein RBBP4
D SPAC29A4.18 prw1; Clr6 histone deacetylase complex subunit Prw1 K10752 RBBP4; histone-binding protein RBBP4
D SPAC25H1.06 pcf3; CAF assembly factor complex subunit B Pcf3 K10752 RBBP4; histone-binding protein RBBP4
C NuRF complex (fruit fly)
D SPCC1672.10 mis16; kinetochore protein Mis16 K10752 RBBP4; histone-binding protein RBBP4
D SPAC29A4.18 prw1; Clr6 histone deacetylase complex subunit Prw1 K10752 RBBP4; histone-binding protein RBBP4
D SPAC25H1.06 pcf3; CAF assembly factor complex subunit B Pcf3 K10752 RBBP4; histone-binding protein RBBP4
C CERF complex
C SRCAP complex
D SPAC11E3.01c swr1; SNF2 family helicase Swr1 K11661 SRCAP; helicase SRCAP/SWR1 [EC:5.6.2.-]
D SPCC550.12 arp6; actin-like protein Arp6 K11662 ACTR6; actin-related protein 6
D SPAPB8E5.09 rvb1; AAA family ATPase Rvb1 K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D SPBC83.08 rvb2; AAA family ATPase Rvb2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D SPAC9G1.13c swc4; Swr1 complex subunit Swc4 K11324 DMAP1; DNA methyltransferase 1-associated protein 1
D SPAC17G8.07 yaf9; YEATS family histone acetyltransferase subunit Yaf9 K11341 YEATS4; YEATS domain-containing protein 4
D SPBC29A3.05 vps71; Swr1 complex subunit Vps71 K11663 ZNHIT1; zinc finger HIT domain-containing protein 1
D SPBP35G2.13c swc2; Swr1 complex complex subunit Swc2 K11664 VPS72; vacuolar protein sorting-associated protein 72
C INO80 complex
D SPAC29B12.01 ino80; SNF2 family helicase Ino80 K11665 INO80; chromatin-remodeling ATPase INO80 [EC:5.6.2.-]
D SPAC222.04c ies6; Ino80 complex subunit Ies6 K11667 INO80C; INO80 complex subunit C
D SPAPB8E5.09 rvb1; AAA family ATPase Rvb1 K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D SPBC83.08 rvb2; AAA family ATPase Rvb2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D SPBC365.10 arp5; actin-like protein Arp5 K11672 ACTR5; actin-related protein 5
D SPAC664.02c arp8; actin-like protein Arp8 K11673 ACTR8; actin-related protein 8
C INO80 complex (yeast)
D SPAC29B12.01 ino80; SNF2 family helicase Ino80 K11665 INO80; chromatin-remodeling ATPase INO80 [EC:5.6.2.-]
D SPAC6B12.05c ies2; Ino80 complex subunit Ies2 K11676 IES2; Ino eighty subunit 2
D SPAC222.04c ies6; Ino80 complex subunit Ies6 K11667 INO80C; INO80 complex subunit C
D SPAC22H12.02 tfg3; transcription factor TFIIF complex subunit Tfg3 K03140 TAF14; transcription initiation factor TFIID/TFIIF subunit
D SPAPB8E5.09 rvb1; AAA family ATPase Rvb1 K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D SPBC83.08 rvb2; AAA family ATPase Rvb2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D SPBP23A10.08 alp5; actin-like protein Arp4 K11400 ARP4; actin-related protein 4
D SPAC23D3.09 arp42; SWI/SNF and RSC complex subunit Arp42 K11400 ARP4; actin-related protein 4
D SPBC365.10 arp5; actin-like protein Arp5 K11672 ACTR5; actin-related protein 5
D SPAC664.02c arp8; actin-like protein Arp8 K11673 ACTR8; actin-related protein 8
C RSC complex
D SPBC4B4.03 rsc1; RSC complex subunit Rsc1 K11756 RSC1_2; chromatin structure-remodeling complex subunit RSC1/2
D SPCC1281.05 rsc7; RSC complex subunit Rsc7 K11761 NPL6; chromatin structure-remodeling complex protein RSC7
D SPBC26H8.09c snf59; SWI/SNF complex subunit Snf59 K11761 NPL6; chromatin structure-remodeling complex protein RSC7
D SPBC1703.02 rsc9; RSC complex subunit Rsc9 K11763 RSC9; chromatin structure-remodeling complex subunit RSC9
D SPAC1071.06 arp9; SWI/SNF and RSC complex subunit Arp9 K11768 ARP9; actin-related protein 9
D SPCC16A11.14 sfh1; RSC complex subunit Sfh1 K11770 SFH1; chromatin structure-remodeling complex subunit SFH1
D SPAC1250.01 snf21; ATP-dependent DNA helicase Snf21 K11786 STH1_SNF2; ATP-dependent helicase STH1/SNF2 [EC:5.6.2.-]
D SPCC1620.14c snf22; ATP-dependent DNA helicase Snf22 K11786 STH1_SNF2; ATP-dependent helicase STH1/SNF2 [EC:5.6.2.-]
C SWI/SNF complex
D SPBC30B4.04c sol1; SWI/SNF complex subunit Sol1 K11771 SWI1; SWI/SNF chromatin-remodeling complex subunit SWI1
D SPAC1250.01 snf21; ATP-dependent DNA helicase Snf21 K11786 STH1_SNF2; ATP-dependent helicase STH1/SNF2 [EC:5.6.2.-]
D SPCC1620.14c snf22; ATP-dependent DNA helicase Snf22 K11786 STH1_SNF2; ATP-dependent helicase STH1/SNF2 [EC:5.6.2.-]
D SPAC2F7.08c snf5; SWI/SNF complex subunit Snf5 K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
D SPAC1071.06 arp9; SWI/SNF and RSC complex subunit Arp9 K11768 ARP9; actin-related protein 9
D SPAC22H12.02 tfg3; transcription factor TFIIF complex subunit Tfg3 K03140 TAF14; transcription initiation factor TFIID/TFIIF subunit
C SWR1 complex
D SPAC11E3.01c swr1; SNF2 family helicase Swr1 K11661 SRCAP; helicase SRCAP/SWR1 [EC:5.6.2.-]
D SPBP23A10.08 alp5; actin-like protein Arp4 K11400 ARP4; actin-related protein 4
D SPAC23D3.09 arp42; SWI/SNF and RSC complex subunit Arp42 K11400 ARP4; actin-related protein 4
D SPAPB8E5.09 rvb1; AAA family ATPase Rvb1 K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D SPBC83.08 rvb2; AAA family ATPase Rvb2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D SPCC550.12 arp6; actin-like protein Arp6 K11662 ACTR6; actin-related protein 6
D SPAC17G8.07 yaf9; YEATS family histone acetyltransferase subunit Yaf9 K11341 YEATS4; YEATS domain-containing protein 4
D SPBC29A3.05 vps71; Swr1 complex subunit Vps71 K11663 ZNHIT1; zinc finger HIT domain-containing protein 1
D SPBP35G2.13c swc2; Swr1 complex complex subunit Swc2 K11664 VPS72; vacuolar protein sorting-associated protein 72
D SPAC9G1.13c swc4; Swr1 complex subunit Swc4 K11324 DMAP1; DNA methyltransferase 1-associated protein 1
D SPAC631.02 putative bromodomain-containing protein K11684 BDF1; bromodomain-containing factor 1
D SPCC1450.02 bdf1; Swr1 complex bromodomain subunit Brf1 K11684 BDF1; bromodomain-containing factor 1
C ASTRA complex
D SPBP16F5.03c tra1; SAGA complex phosphatidylinositol pseudokinase Tra1 K08874 TRRAP; transformation/transcription domain-associated protein
D SPAC1F5.11c tra2; phosphatidylinositol kinase-like protein Tra2 K08874 TRRAP; transformation/transcription domain-associated protein
D SPAPB8E5.09 rvb1; AAA family ATPase Rvb1 K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
D SPBC83.08 rvb2; AAA family ATPase Rvb2 K11338 RUVBL2; RuvB-like protein 2 [EC:5.6.2.3]
D SPAC458.03 tel2; Tel2/Rad-5/Clk-2 family protein Tel2 K11137 TELO2; telomere length regulation protein
D SPCC622.13c tti1; Tel Two Interacting protein 1 K20403 TTI1; TELO2-interacting protein 1
D SPAC1006.02 asa1; ASTRA-associated protein 1 Asa1 K24767 ASA1; ASTRA-associated protein 1
C Other chromatin remodeling factors
D SPCC1235.05c fft2; putative protein Fft2 K14439 SMARCAD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 [EC:5.6.2.-]
D SPAC20G8.08c fft1; putative protein Fft1 K14439 SMARCAD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 [EC:5.6.2.-]
D SPAC25A8.01c fft3; putative protein Fft3 K14439 SMARCAD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 [EC:5.6.2.-]
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AProkaryotic type
B Nucleoid associated proteins
C HNS (histone-like nucleoid structuring protein)
C HU (heat unstable protein)
C IHF (integration host factor)
C Other nucleoid associated proteins
B Chromosome partitioning proteins
C MukBEF complex
C Condensin-like complex
C Divisome proteins
C Inhibitors of FtsZ assembly
C Other chromosome partitioning proteins
D SPBC30B4.06c putative GIDA family tRNA uridine 5-carboxymethylaminomethyl modification enzyme K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 16, 2024