+D Protein KO
#
Membrane Trafficking - Thalassiosira pseudonana
%
!
AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
C Septins
C DOC-2 proteins
C Acrosomal exocytosis proteins
C Phospholipases
D THAPS_263246 phospholipase C K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D THAPSDRAFT_261844 phospholipase K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
C Kinases and associated proteins
D THAPSDRAFT_18434 predicted protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D THAPSDRAFT_264335 phosphatidylinositol-4-phosphate 5-kinase (PIP5K)-like protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D THAPSDRAFT_6290 NDK2; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D THAPSDRAFT_12070 NDK1; probable nucleoside disphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D THAPSDRAFT_31091 NDK3; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D THAPSDRAFT_3779 NDK4; probable nuceloside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
C Others
B Small GTPases and associated proteins
C Rab GTPases
D THAPSDRAFT_33126 rab-type small G protein K07901 RAB8A; Ras-related protein Rab-8A
D THAPSDRAFT_33199 TpSec4b; rab-type small GTPase K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
D THAPSDRAFT_23992 predicted protein K18270 RAB3GAP1; Rab3 GTPase-activating protein catalytic subunit
D THAPS_41291 CAM1; calmodulin K02183 CALM; calmodulin
D THAPSDRAFT_33600 EF hand-containing protein K02183 CALM; calmodulin
D THAPSDRAFT_42194 EF hand-containing protein K02183 CALM; calmodulin
D THAPS_41372 predicted protein K02183 CALM; calmodulin
D THAPSDRAFT_25977 syntaxin-interacting protein unc-18 K15292 STXBP1; syntaxin-binding protein 1
D THAPSDRAFT_261716 hypothetical protein K19942 GAS8; dynein regulatory complex subunit 4
D THAPSDRAFT_2555 inositol 5-phosphatase K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D THAPSDRAFT_264438 peroxisomal targeting signal receptor K13342 PEX5; peroxin-5
D THAPSDRAFT_2415 hypothetical protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D THAPSDRAFT_262762 RAB geranylgeranyl transferase K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D THAPSDRAFT_268859 GGTB1; probable beta subunit of type II geranylgeranyl transferase K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
C Rho GTPases
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
D THAPSDRAFT_1471 predicted protein K17637 EXOC2; exocyst complex component 2
D THAPSDRAFT_25023 predicted protein K19985 EXOC6; exocyst complex component 6
C Exocyst complex assembly proteins
B Others
C Exomer complex
C Others
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
D THAPSDRAFT_33228 syntaxin, epimorphin family K08486 STX1B_2_3; syntaxin 1B/2/3
C Stx-Endo
C Stx-TGN / EE
D THAPSDRAFT_2467 predicted protein K08489 STX16; syntaxin 16
C Stx-cisGolgi
D THAPSDRAFT_262803 syntaxin K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
B SNAP-25[N] (Qb)
C Vti1
D THAPSDRAFT_12035 predicted protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
D THAPSDRAFT_268625 v-snare protein, Vti1 C-terminal half-like protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
C NPSN
C Gos1 (Gos28)
D THAPSDRAFT_24068 SNARE component K08495 GOSR1; golgi SNAP receptor complex member 1
D THAPSDRAFT_bd1692 SNARE component K08495 GOSR1; golgi SNAP receptor complex member 1
C Bos1 / Membrin
D THAPSDRAFT_2454 predicted protein K08496 GOSR2; golgi SNAP receptor complex member 2
C Sec20
B SNAP-25[C] (Qc)
C STX6
D THAPSDRAFT_24585 syntaxin, t-snare coiled-coil domain family K08498 STX6; syntaxin 6
C STX8
C STX10
C Bet1
D THAPSDRAFT_5947 predicted protein K08504 BET1; blocked early in transport 1
C Sft1
C Syp7
C Use1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
C SNAP-29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D THAPS_803 synaptobrevin K08515 VAMP7; vesicle-associated membrane protein 7
D THAPSDRAFT_263742 synaptobrevin K08515 VAMP7; vesicle-associated membrane protein 7
C Ykt6
D THAPSDRAFT_9617 synaptobrevin K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D THAPSDRAFT_30919 hypothetical protein K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D THAPSDRAFT_25977 syntaxin-interacting protein unc-18 K15292 STXBP1; syntaxin-binding protein 1
D THAPSDRAFT_33072 sec1-family transport protein K19998 SCFD1; sec1 family domain-containing protein 1
C Palmitoyltransferases
D THAPSDRAFT_22347 predicted protein K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
C Others
D THAPSDRAFT_3575 predicted protein K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D THAPSDRAFT_11221 predicted protein K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D THAPSDRAFT_269412 hypothetical protein K15296 NAPA; alpha-soluble NSF attachment protein
D THAPSDRAFT_267952 hypothetical protein K13525 VCP; transitional endoplasmic reticulum ATPase
D THAPSDRAFT_25024 predicted protein K14012 NSFL1C; UBX domain-containing protein 1
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D THAPSDRAFT_269540 CHC; clathrin heavy chain K04646 CLTC; clathrin heavy chain
C Dynamin
D THAPS_35266 DYN1; dynamin GTPase, switch/motor protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D THAPSDRAFT_263994 predicted protein K11824 AP2A; AP-2 complex subunit alpha
D THAPSDRAFT_263997 APA1; alpha subunit of tetrameric clathrin adaptor complex AP1 K11824 AP2A; AP-2 complex subunit alpha
D THAPSDRAFT_39847 APM2; clathrin adaptor complex subunit K11826 AP2M1; AP-2 complex subunit mu-1
D THAPSDRAFT_36490 APS2; AP17, clathrin adaptor complex AP2 small chain K11827 AP2S1; AP-2 complex subunit sigma-1
C Other core components
D THAPSDRAFT_1311 predicted protein K12471 EPN; epsin
D THAPSDRAFT_269120 hsp70; heat shock protein 70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D THAPSDRAFT_261109 HSP70 domain-containing protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D THAPSDRAFT_28189 HSP70_3; heat shock protein, HSP70, hsc70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D THAPSDRAFT_18434 predicted protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D THAPSDRAFT_264335 phosphatidylinositol-4-phosphate 5-kinase (PIP5K)-like protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
D THAPSDRAFT_2555 inositol 5-phosphatase K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
C Kinases
D THAPSDRAFT_264854 dual-specificity tyrosine-phosphorylation regulated kinase 1a-like protein K08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]
C Ubiquitin E3 ligases
C Others
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D THAPS_35266 DYN1; dynamin GTPase, switch/motor protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C Flotillin-dependent endocytosis
C GRAF1-dependent endocytosis
D THAPSDRAFT_39299 ARF3; adp-ribosylation factor K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf6-dependent endocytosis
C RhoA-dependent endocytosis
D THAPS_35266 DYN1; dynamin GTPase, switch/motor protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
B Macropinocytosis
C Ras GTPases
C Kinases
D THAPSDRAFT_36937 predicted protein K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D THAPSDRAFT_264395 phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D THAPSDRAFT_270069 hypothetical protein K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
C Phospholipase C
D THAPS_263246 phospholipase C K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
C Sorting nexins
D THAPSDRAFT_34620 predicted protein K17917 SNX1_2; sorting nexin-1/2
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
C F-BAR proteins
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
D THAPSDRAFT_261381 canine-like rab-type small G protein K07889 RAB5C; Ras-related protein Rab-5C
C Rab associated proteins
D THAPSDRAFT_2555 inositol 5-phosphatase K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D THAPSDRAFT_36937 predicted protein K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D THAPSDRAFT_264395 phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D THAPSDRAFT_3934 predicted protein K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D THAPSDRAFT_750 vacuolar protein sorting Vps45 K12479 VPS45; vacuolar protein sorting-associated protein 45
D THAPSDRAFT_4674 predicted protein K20027 ZDHHC1_11; palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225]
B Arf GTPases and associated proteins
C Arf GTPases
D THAPSDRAFT_39299 ARF3; adp-ribosylation factor K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf associated proteins
D THAPSDRAFT_261516 ArfGAP K12489 ACAP; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein
D THAPSDRAFT_261261 ArfGAP K12486 SMAP; stromal membrane-associated protein
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
D THAPSDRAFT_260874 pi 4-kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D THAPS_29000 predicted protein K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D THAPSDRAFT_261381 canine-like rab-type small G protein K07889 RAB5C; Ras-related protein Rab-5C
D THAPSDRAFT_35818 predicted protein K07897 RAB7A; Ras-related protein Rab-7A
D THAPSDRAFT_264722 ras superfamily gtp-binding protein K07897 RAB7A; Ras-related protein Rab-7A
D THAPS_18303 canine-like rab-type small G protein K07890 RAB21; Ras-related protein Rab-21
C Retromer subcomplex
D THAPSDRAFT_36337 predicted protein K18468 VPS35; vacuolar protein sorting-associated protein 35
D THAPSDRAFT_11576 predicted protein K18467 VPS29; vacuolar protein sorting-associated protein 29
D THAPS_38123 predicted protein K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
D THAPSDRAFT_20998 microtubule-associated protein K16536 HOOK3; protein HOOK3
C Rab associated proteins
D THAPSDRAFT_36937 predicted protein K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D THAPSDRAFT_264395 phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D THAPSDRAFT_26706 PSA7; proteasome subunit alpha type 7-1 K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D THAPSDRAFT_2415 hypothetical protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D THAPSDRAFT_262762 RAB geranylgeranyl transferase K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D THAPSDRAFT_268859 GGTB1; probable beta subunit of type II geranylgeranyl transferase K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
B Arf GTPases and associated proteins
C Arf GTPases
D THAPS_7249 ARF5; ADP-ribosylation factor like protein K07955 ARL8; ADP-ribosylation factor-like protein 8
C BLOC-one-related complex (BORC)
C N-acetyl transferase complex C (NatC)
D THAPSDRAFT_33075 n-acetyl transferase K00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
C ESCRT-I complex
D THAPS_23630 predicted protein K12183 TSG101; ESCRT-I complex subunit TSG101
D THAPSDRAFT_9031 predicted protein K12184 VPS28; ESCRT-I complex subunit VPS28
D THAPSDRAFT_268881 hypothetical protein K12185 VPS37; ESCRT-I complex subunit VPS37
C ESCRT-II complex
D THAPSDRAFT_32191 predicted protein K12188 SNF8; ESCRT-II complex subunit VPS22
D THAPSDRAFT_37819 predicted protein K12189 VPS25; ESCRT-II complex subunit VPS25
D THAPS_23464 predicted protein K12190 VPS36; ESCRT-II complex subunit VPS36
C ESCRT-III complex
D THAPSDRAFT_7887 predicted protein K12197 CHMP1; charged multivesicular body protein 1
D THAPSDRAFT_39225 predicted protein K12191 CHMP2A; charged multivesicular body protein 2A
D THAPSDRAFT_bd409 copia-like retroelement pol polyprotein found-like protein K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D THAPSDRAFT_42320 hypothetical protein K12198 CHMP5; charged multivesicular body protein 5
D THAPSDRAFT_3459 predicted protein K12195 CHMP6; charged multivesicular body protein 6
D THAPSDRAFT_821 VPS4; vacuolar protein sorting-associated protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
D THAPSDRAFT_8959 predicted protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
D THAPSDRAFT_24658 predicted protein K12199 VTA1; vacuolar protein sorting-associated protein VTA1
B Tethering complex
C CORVET complex
D THAPSDRAFT_264276 hypothetical protein K20178 VPS8; vacuolar protein sorting-associated protein 8
D THAPSDRAFT_24183 predicted protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D THAPSDRAFT_22008 predicted protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D THAPSDRAFT_262501 hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
C Hops complex
D THAPSDRAFT_24183 predicted protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D THAPSDRAFT_22008 predicted protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D THAPSDRAFT_262501 hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D THAPSDRAFT_24171 predicted protein K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
D THAPSDRAFT_24796 predicted protein K20184 VPS41; vacuolar protein sorting-associated protein 41
B Acidification regulators
C Rabconnectin-3 complex
C RAVE complex
D THAPSDRAFT_38460 hypothetical protein K03094 SKP1; S-phase kinase-associated protein 1
D THAPSDRAFT_10077 hypothetical protein K03094 SKP1; S-phase kinase-associated protein 1
B Others
C AP-3 complex
D THAPSDRAFT_263963 hypothetical protein K12396 AP3D; AP-3 complex subunit delta
D THAPSDRAFT_261056 APB3; beta subunit of clathrin adaptor protein AP3 K12397 AP3B; AP-3 complex subunit beta
D THAPSDRAFT_39741 APM3; mu subunit of clathrin adaptor complex AP3 K12398 AP3M; AP-3 complex subunit mu
D THAPS_28984 APS3; sigma subunit of clathrin adaptor protein AP3 K12399 AP3S; AP-3 complex subunit sigma
C BLOC-1 complex
C BLOC-1 complex (yeast)
C BLOC-2 complex
C BLOC-3 complex
C Ferlins
C Others
D THAPSDRAFT_15123 predicted protein K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
D THAPS_23528 rab-type small GTPase K07904 RAB11A; Ras-related protein Rab-11A
C Rab4 associated proteins
C Rab11 associated proteins
D THAPSDRAFT_1303 predicted protein K20241 WDR44; WD repeat-containing protein 44
D THAPSDRAFT_10025 sec13-related protein K14004 SEC13; protein transport protein SEC13
D THAPSDRAFT_25023 predicted protein K19985 EXOC6; exocyst complex component 6
C Other Rab GTPase associated proteins
D THAPSDRAFT_24736 receptor mediated endocytosis protein-like protein K12483 EHD1; EH domain-containing protein 1
D THAPSDRAFT_2555 inositol 5-phosphatase K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D THAPSDRAFT_261516 ArfGAP K12489 ACAP; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein
D THAPSDRAFT_25135 predicted protein K20163 DENND4; DENN domain-containing protein 4
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D THAPSDRAFT_5630 predicted protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D THAPSDRAFT_31160 suppressor of actin mutations protein-like protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D THAPSDRAFT_23311 predicted protein K20299 VPS53; vacuolar protein sorting-associated protein 53
D THAPSDRAFT_22308 predicted protein K23288 VPS50; syndetin
C WASH complex
D THAPSDRAFT_34228 hypothetical protein K18464 RTSC; WASH complex subunit strumpellin
D THAPSDRAFT_262956 hypothetical protein K18465 MRT43; WASH complex subunit 7
C Retriever complex
D THAPSDRAFT_11576 predicted protein K18467 VPS29; vacuolar protein sorting-associated protein 29
C Others
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
D THAPSDRAFT_3582 rab-like rab-type small G protein K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D THAPSDRAFT_6086 predicted protein K20286 TMF1; TATA element modulatory factor
D THAPSDRAFT_261228 hypothetical protein K10419 DYNLRB; dynein light chain roadblock-type
D THAPSDRAFT_24828 predicted protein K04648 DCTN1; dynactin 1
D THAPSDRAFT_2555 inositol 5-phosphatase K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D THAPSDRAFT_10699 predicted protein K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
B Arf GTPases and associated proteins
C Arf GTPases
D THAPSDRAFT_39299 ARF3; adp-ribosylation factor K07937 ARF1_2; ADP-ribosylation factor 1/2
D THAPSDRAFT_37988 ARF1; adp-ribosylation factor 1 K07942 ARL1; ADP-ribosylation factor-like protein 1
D THAPSDRAFT_268619 adp-ribosylation factor-related protein K07952 ARFRP1; ADP-ribosylation factor related protein 1
C Arf GTPase associated proteins
D THAPSDRAFT_20719 predicted protein K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
D THAPSDRAFT_261261 ArfGAP K12486 SMAP; stromal membrane-associated protein
D THAPS_263191 ArfGEF K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
D THAPSDRAFT_262359 guanyl nucleotide exchange factor K18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D THAPSDRAFT_11664 predicted protein K20289 COG2; conserved oligomeric Golgi complex subunit 2
D THAPSDRAFT_8885 predicted protein K20289 COG2; conserved oligomeric Golgi complex subunit 2
D THAPSDRAFT_21420 predicted protein K20290 COG3; conserved oligomeric Golgi complex subunit 3
D THAPSDRAFT_11085 predicted protein K20291 COG4; conserved oligomeric Golgi complex subunit 4
D THAPSDRAFT_22265 predicted protein K20292 COG5; conserved oligomeric Golgi complex subunit 5
D THAPSDRAFT_3926 predicted protein K20293 COG6; conserved oligomeric Golgi complex subunit 6
D THAPSDRAFT_269802 predicted protein K20294 COG7; conserved oligomeric Golgi complex subunit 7
D THAPS_6823 predicted protein K20295 COG8; conserved oligomeric Golgi complex subunit 8
C GARP complex
D THAPSDRAFT_5630 predicted protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D THAPSDRAFT_31160 suppressor of actin mutations protein-like protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D THAPSDRAFT_23311 predicted protein K20299 VPS53; vacuolar protein sorting-associated protein 53
D THAPSDRAFT_22112 predicted protein K17600 VPS54; vacuolar protein sorting-associated protein 54
C TRAPP complex II
D THAPSDRAFT_31778 predicted protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D THAPSDRAFT_19622 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D THAPSDRAFT_22307 vesicle-transport protein Bet3 K20302 TRAPPC3; trafficking protein particle complex subunit 3
D THAPSDRAFT_34702 predicted protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D THAPSDRAFT_38945 predicted protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D THAPSDRAFT_3516 predicted protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
D THAPS_25373 predicted protein K20307 TRAPPC10; trafficking protein particle complex subunit 10
D THAPSDRAFT_1602 predicted protein K20310 TRAPPC13; trafficking protein particle complex subunit 13
B Others
C AP-1 complex
D THAPSDRAFT_269744 APG2; gamma subunit of tetrameric clathrin adaptor complex AP2 K12391 AP1G1; AP-1 complex subunit gamma-1
D THAPSDRAFT_41687 APB1; beta subunit of tetrameric clathrin adaptor complex AP1 K12392 AP1B1; AP-1 complex subunit beta-1
D THAPSDRAFT_37264 APM1; mu subunit of tetrameric clathrin adaptor complex AP1 K12393 AP1M; AP-1 complex subunit mu
D THAPSDRAFT_33667 predicted protein K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
D THAPSDRAFT_263963 hypothetical protein K12396 AP3D; AP-3 complex subunit delta
D THAPSDRAFT_261056 APB3; beta subunit of clathrin adaptor protein AP3 K12397 AP3B; AP-3 complex subunit beta
D THAPSDRAFT_39741 APM3; mu subunit of clathrin adaptor complex AP3 K12398 AP3M; AP-3 complex subunit mu
D THAPS_28984 APS3; sigma subunit of clathrin adaptor protein AP3 K12399 AP3S; AP-3 complex subunit sigma
C AP-4 complex
D THAPS_596 predicted protein K12400 AP4E1; AP-4 complex subunit epsilon-1
D THAPSDRAFT_31014 mu subunit of AP4-like protein K12402 AP4M1; AP-4 complex subunit mu-1
D THAPSDRAFT_5631 APS4; sigma subunit of clathrin adaptor complex AP4 K12403 AP4S1; AP-4 complex subunit sigma-1
C GGA
C Aftiphilin/p200/gamma-synergin complex
C Others
D THAPSDRAFT_261844 phospholipase K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D THAPSDRAFT_260874 pi 4-kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D THAPS_29000 predicted protein K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D THAPSDRAFT_18434 predicted protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D THAPSDRAFT_264335 phosphatidylinositol-4-phosphate 5-kinase (PIP5K)-like protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D THAPSDRAFT_270069 hypothetical protein K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
D THAPSDRAFT_37441 predicted protein K20318 SYS1; protein SYS1
D THAPSDRAFT_36568 predicted protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D THAPSDRAFT_22223 predicted protein K23544 SERINC1; serine incorporator 1
D THAPSDRAFT_33676 predicted protein K26752 TVP23; golgi apparatus membrane protein TVP23
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D THAPSDRAFT_39497 arf-type small G protein K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D THAPSDRAFT_38322 sar1-type small G protein K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D THAPSDRAFT_10025 sec13-related protein K14004 SEC13; protein transport protein SEC13
D THAPSDRAFT_22963 predicted protein K14005 SEC31; protein transport protein SEC31
D THAPSDRAFT_22248 hypothetical protein K14006 SEC23; protein transport protein SEC23
D THAPSDRAFT_269747 coatomer COPII K14007 SEC24; protein transport protein SEC24
C TRAPP complex I
D THAPSDRAFT_31778 predicted protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D THAPSDRAFT_19622 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D THAPSDRAFT_22307 vesicle-transport protein Bet3 K20302 TRAPPC3; trafficking protein particle complex subunit 3
D THAPSDRAFT_34702 predicted protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D THAPSDRAFT_38945 predicted protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D THAPSDRAFT_3516 predicted protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D THAPSDRAFT_22589 predicted protein K20347 TMED2; p24 family protein beta-1
D THAPSDRAFT_18462 predicted protein K20352 TMED10; p24 family protein delta-1
C PDI family proteins
D THAPSDRAFT_21965 predicted protein K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Rab GTPases
D THAPSDRAFT_22792 ypt1-like rab-type small G protein K07874 RAB1A; Ras-related protein Rab-1A
D THAPSDRAFT_843 rab-type small G protein K07874 RAB1A; Ras-related protein Rab-1A
D THAPSDRAFT_18220 predicted protein K07877 RAB2A; Ras-related protein Rab-2A
C Rab associated proteins
D THAPSDRAFT_262611 hypothetical protein K20372 TBC1D20; TBC1 domain family member 20
D THAPSDRAFT_36419 hypothetical protein K20360 TBC1D22; TBC1 domain family member 2
C ER-Golgi intermediate compartment (ERGIC) proteins
D THAPSDRAFT_40232 OAM1; mannosyl-oligosaccharide 1,2-alpha-mannosidase K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D THAPSDRAFT_268640 mannosyloligosaccharid alpha-mannosidase K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D THAPSDRAFT_34968 mannosyl-oligosaccharide alpha-mannosidase K23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]
D THAPSDRAFT_34295 predicted protein K20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3
D THAPSDRAFT_27656 hsp70_4; heat shock protein/chaperone K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
D THAPSDRAFT_38578 BIP2; luminal binding protein K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D THAPSDRAFT_34876 COP1; coatomer protein subunit alpha K05236 COPA; coatomer subunit alpha
D THAPSDRAFT_26212 COP2; coatomer protein subunit beta 1 K17301 COPB1; coatomer subunit beta
D THAPSDRAFT_22092 COP3; coatomer protein subunit beta2 K17302 COPB2; coatomer subunit beta'
D THAPSDRAFT_269663 COP4; coatomer protein subunit gamma K17267 COPG; coatomer subunit gamma
D THAPSDRAFT_39913 COP6; coatomer protein subunit epsilon K17268 COPE; coatomer subunit epsilon
D THAPSDRAFT_23050 predicted protein K20472 COPZ; coatomer subunit zeta
C NRZ (DSL1) complex
D THAPS_25363 predicted protein K11578 ZW10; protein transport protein DSL1/ZW10
C Golgi to ER traffic proteins (GET)
D THAPSDRAFT_39841 anion-transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D THAPSDRAFT_1704 predicted protein K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
C Rab GTPases
D THAPSDRAFT_3582 rab-like rab-type small G protein K07893 RAB6A; Ras-related protein Rab-6A
C Rab associated proteins
D THAPSDRAFT_34218 predicted protein K10949 KDELR; ER lumen protein retaining receptor
D THAPSDRAFT_36419 hypothetical protein K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
C FXYD proteins
C YIPF proteins
D THAPSDRAFT_5790 predicted protein K22940 YIPF1_2; protein YIPF1/2
D THAPSDRAFT_38331 uncharacterized protein K20363 YIPF5_7; protein YIPF5/7
D THAPSDRAFT_264863 uncharacterized protein K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D THAPSDRAFT_32843 predicted protein K23563 EMC2; ER membrane protein complex subunit 2
D THAPS_23388 predicted protein K23564 EMC3; ER membrane protein complex subunit 3
D THAPSDRAFT_33995 hypothetical protein K23565 EMC4; ER membrane protein complex subunit 4
D THAPSDRAFT_22722 predicted protein K23568 EMC7; ER membrane protein complex subunit 7
D THAPSDRAFT_5178 predicted protein K23569 EMC8_9; ER membrane protein complex subunit 8/9
C SEC61 complex
D THAPS_25355 SEC61-1; protein translocase complex subunit K10956 SEC61A; protein transport protein SEC61 subunit alpha
D THAPSDRAFT_28769 SEC61-2; protein transportor K10956 SEC61A; protein transport protein SEC61 subunit alpha
D THAPS_38207 predicted protein K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C TRAP complex
C Multi-pass translocon (MPT) complex
D THAPSDRAFT_269110 hypothetical protein K21891 TMCO1; calcium load-activated calcium channel
C Post-GPI attachment to proteins factors (PGAP)
D THAPSDRAFT_4277 predicted protein K05294 PGAP1; GPI inositol-deacylase [EC:3.-.-.-]
C Others
D THAPSDRAFT_33072 sec1-family transport protein K19998 SCFD1; sec1 family domain-containing protein 1
D THAPSDRAFT_21600 predicted protein K22556 MANF; mesencephalic astrocyte-derived neurotrophic factor
D THAPSDRAFT_22433 predicted protein K17339 ATL; atlastin [EC:3.6.5.-]
#
AAutophagy
B Autophagosome formation proteins
C ULK complex
D THAPSDRAFT_2791 predicted protein K19730 ATG101; autophagy-related protein 101
C Atg1 complex
D THAPSDRAFT_269100 hypothetical protein K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
C PI3K complex
D THAPSDRAFT_36937 predicted protein K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D THAPSDRAFT_264395 phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D THAPSDRAFT_3934 predicted protein K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D THAPSDRAFT_6066 predicted protein K08334 BECN; beclin
C ATG9 transmembrane protein
D THAPSDRAFT_21712 predicted protein K17907 ATG9; autophagy-related protein 9
C Atg18-Atg2 complex
C Atg12 conjugation proteins
D THAPSDRAFT_34701 predicted protein K08336 ATG12; ubiquitin-like protein ATG12
D THAPSDRAFT_262157 ubiquitin activating enzyme e1-like protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D THAPSDRAFT_262070 WD40-repeat protein K17890 ATG16L1; autophagy-related protein 16-1
C Atg8 conjugation proteins
D THAPSDRAFT_32176 microtubule-associated protein K08341 GABARAP; GABA(A) receptor-associated protein
D THAPSDRAFT_10581 predicted protein K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D THAPSDRAFT_262157 ubiquitin activating enzyme e1-like protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D THAPS_35360 autophagocytosis protein-like protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D THAPS_263310 cytosolic alpha-mannosidase K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
D THAPSDRAFT_34170 probable aspartyl aminopeptidase K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
D THAPSDRAFT_32859 probable aspartyl aminopeptidase K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
C Other Cvt associated proteins
D THAPSDRAFT_261325 hypothetical protein K08332 VAC8; vacuolar protein 8
B Mitophagy
C Cargo receptors
C Scaffold proteins
C PINK1-Parkin associated proteins
D THAPSDRAFT_7633 predicted protein K19513 CLEC16A; protein CLEC16A
D THAPSDRAFT_261472 hypothetical protein K17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
C Other mitophagy associated proteins
B Pexophagy
C Selective cargos
D THAPSDRAFT_263695 hypothetical protein K13336 PEX3; peroxin-3
C Cargo receptors
C Other pexophagy associated proteins
B Aggrephagy
C Cargo receptors
C Scaffold proteins
C Other aggrephagy associated proteins
D THAPSDRAFT_267952 hypothetical protein K13525 VCP; transitional endoplasmic reticulum ATPase
D THAPSDRAFT_15819 predicted protein K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
B Xenophagy
C Cargo receptors
C Other xenophagy associated proteins
B Chaperone mediated autophagy (CMA)
C Selective cargos
D THAPSDRAFT_11761 ALDO4; Fructose-1,6-bisphosphatase aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D THAPSDRAFT_28334 GAPD4; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D THAPSDRAFT_28241 gapC3; glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D THAPSDRAFT_28239 triosephosphate isomerase/glyceraldehyde-3-phosphate dehydrogenase precursor K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D THAPSDRAFT_31383 GAPD1; glyceraldehyde-3-phosphate dehydrogenase precursor K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D THAPSDRAFT_28350 PGAM1; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D THAPSDRAFT_260919 hypothetical protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D THAPSDRAFT_17651 predicted protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D THAPSDRAFT_17735 predicted protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D THAPSDRAFT_263397 PGAM4; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D THAPSDRAFT_27850 PGAM2; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D THAPSDRAFT_40393 PYK1; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D THAPSDRAFT_264583 PYK4; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D THAPSDRAFT_22345 PYK2; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D THAPSDRAFT_31810 predicted protein K00873 PK; pyruvate kinase [EC:2.7.1.40]
D THAPSDRAFT_21756 predicted protein K04523 UBQLN; ubiquilin
D THAPSDRAFT_4224 predicted protein K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D THAPSDRAFT_269120 hsp70; heat shock protein 70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D THAPSDRAFT_261109 HSP70 domain-containing protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D THAPSDRAFT_28189 HSP70_3; heat shock protein, HSP70, hsc70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D THAPSDRAFT_6285 HSP90_1; HSP90 family member K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
D THAPSDRAFT_37576 predicted protein K09560 ST13; suppressor of tumorigenicity protein 13
C Other CMA associated proteins
D THAPSDRAFT_41829 translation elongation factor alpha K03231 EEF1A; elongation factor 1-alpha
D THAPSDRAFT_bd1861 hypothetical protein K03231 EEF1A; elongation factor 1-alpha
D THAPSDRAFT_3858 predicted protein K03231 EEF1A; elongation factor 1-alpha
D THAPSDRAFT_15093 serine carboxypeptidase K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
D THAPSDRAFT_261325 hypothetical protein K08332 VAC8; vacuolar protein 8
C Midbophagy
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
C mTORC1 complex
D THAPSDRAFT_29771 phosphatidylinositol 3-kinase (PI3K)-like protein K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D THAPSDRAFT_4260 WD40-repeat protein K08266 MLST8; target of rapamycin complex subunit LST8
D THAPSDRAFT_24683 predicted protein K07204 RAPTOR; regulatory associated protein of mTOR
C mTORC2 complex
D THAPSDRAFT_29771 phosphatidylinositol 3-kinase (PI3K)-like protein K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D THAPSDRAFT_4260 WD40-repeat protein K08266 MLST8; target of rapamycin complex subunit LST8
C SEACIT/GATOR1 complex
D THAPSDRAFT_261392 hypothetical protein K20405 NPRL2; nitrogen permease regulator 2
C SEACAT/GATOR2 complex
D THAPSDRAFT_20675 predicted protein K20408 WDR24; SEA/GATOR complex protein SEA2/WDR24
D THAPSDRAFT_15822 predicted protein K14299 SEH1; nucleoporin SEH1
D THAPSDRAFT_10025 sec13-related protein K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
C Rab GTPases
D THAPSDRAFT_22792 ypt1-like rab-type small G protein K07874 RAB1A; Ras-related protein Rab-1A
D THAPSDRAFT_843 rab-type small G protein K07874 RAB1A; Ras-related protein Rab-1A
D THAPSDRAFT_33126 rab-type small G protein K07901 RAB8A; Ras-related protein Rab-8A
D THAPSDRAFT_33199 TpSec4b; rab-type small GTPase K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
C Others
D THAPSDRAFT_26536 SNF1; sucrose non-fermenting (SNF-1) related serine threonine protein kinase K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D THAPSDRAFT_1585 serine threonine phosphatase K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D THAPSDRAFT_40627 phosphatase of serine threonine protein phosphatase K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D THAPSDRAFT_10012 predicted protein K17606 IGBP1; immunoglobulin-binding protein 1
D THAPSDRAFT_26635 amino acid/polyamine transporter K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D THAPSDRAFT_262016 amino acid/polyamine transporter K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D THAPSDRAFT_268823 amino acid/polyamine transporter K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
#
AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
C Nox associated proteins
B Actin-binding proteins
C Myosins
D THAPSDRAFT_38230 predicted protein K10357 MYO5; myosin V
C Arp2/3 complex
C Nucleation-promoting factors (NPFs)
D THAPSDRAFT_261692 hypothetical protein K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1
C Others
D THAPSDRAFT_4830 the actin binding protein cofilin-like protein K05765 CFL; cofilin
B Mucins
C Membrane bound mucins
C Secretory mucins
B Rab GTPases of specific organelles
C Melanosome
C Auto phagosome
D THAPSDRAFT_262070 WD40-repeat protein K17890 ATG16L1; autophagy-related protein 16-1
C Lipid droplets
D THAPSDRAFT_32223 at-like rab-type small G protein K07910 RAB18; Ras-related protein Rab-18
C Mitochondrion
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
C Rho guanine nucleotide exchange factors (GEFs)
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 15, 2024