+D
#
Spliceosome
!
ACommon components
B Common spliceosomal components
C Cap binding complex
D K12882 NCBP1, CBP80; nuclear cap-binding protein subunit 1
D K12883 NCBP2, CBP20; nuclear cap-binding protein subunit 2
C hnRNP proteins
D K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
D K12884 HNRNPC; heterogeneous nuclear ribonucleoprotein C1/C2
D K12885 RBMX, HNRNPG; heterogeneous nuclear ribonucleoprotein G
D K12886 HNRNPK; heterogeneous nuclear ribonucleoprotein K
D K12887 HNRNPM; heterogeneous nuclear ribonucleoprotein M
D K12888 HNRNPU; heterogeneous nuclear ribonucleoprotein U
D K12889 PCBP1; poly(rC)-binding protein 1
C SR proteins
D K12890 SRSF1, SFRS1, ASF, SF2; serine/arginine-rich splicing factor 1
D K12891 SRSF2_8, SFRS2A_B; serine/arginine-rich splicing factor 2/8
D K12892 SRSF3, SFRS3; serine/arginine-rich splicing factor 3
D K12893 SRSF4_5_6, SFRS4_5_6; serine/arginine-rich splicing factor 4/5/6
D K12896 SRSF7, SFRS7; serine/arginine-rich splicing factor 7
D K21123 SRSF9, SFRS9; serine/arginine-rich splicing factor 9
D K12900 SRSF10, FUSIP1; serine/arginine-rich splicing factor 10
D K12897 TRA2; transformer-2 protein
C General mRNP proteins
D K13087 BCLAF1; bcl2 associated transcription factor 1
D K13088 ELAVL1, HUR; ELAV-like protein 1
D K13089 ILF2; interleukin enhancer-binding factor 2
D K13090 ILF3; interleukin enhancer-binding factor 3
D K13091 RBM23_39; RNA-binding protein 23/39
D K09276 YBX1, NSEP1; Y-box-binding protein 1
D K13092 ZC3H18; nuclear protein NHN1
#
AComplex A
B U1 snRNP components
C Sm proteins
D K11086 SNRPB, SMB; small nuclear ribonucleoprotein B and B'
D K11087 SNRPD1, SMD1; small nuclear ribonucleoprotein D1
D K11096 SNRPD2, SMD2; small nuclear ribonucleoprotein D2
D K11088 SNRPD3, SMD3; small nuclear ribonucleoprotein D3
D K11097 SNRPE, SME; small nuclear ribonucleoprotein E
D K11098 SNRPF, SMF; small nuclear ribonucleoprotein F
D K11099 SNRPG, SMG; small nuclear ribonucleoprotein G
C U1 snRNP specific factors
D K11093 SNRP70; U1 small nuclear ribonucleoprotein 70kDa
D K11091 SNRPA; U1 small nuclear ribonucleoprotein A
D K11095 SNRPC; U1 small nuclear ribonucleoprotein C
C U1 related factors
D K12823 DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2 [EC:5.6.2.7]
D K12821 PRPF40, PRP40; pre-mRNA-processing factor 40
D K12822 RBM25, S164; RNA-binding protein 25
D K12824 TCERG1, CA150; transcription elongation regulator 1
B U2 snRNP components
C Sm proteins
D K11086 SNRPB, SMB; small nuclear ribonucleoprotein B and B'
D K11087 SNRPD1, SMD1; small nuclear ribonucleoprotein D1
D K11096 SNRPD2, SMD2; small nuclear ribonucleoprotein D2
D K11088 SNRPD3, SMD3; small nuclear ribonucleoprotein D3
D K11097 SNRPE, SME; small nuclear ribonucleoprotein E
D K11098 SNRPF, SMF; small nuclear ribonucleoprotein F
D K11099 SNRPG, SMG; small nuclear ribonucleoprotein G
C U2 snRNP specific factors
D K11092 SNRPA1; U2 small nuclear ribonucleoprotein A'
D K11094 SNRPB2; U2 small nuclear ribonucleoprotein B''
D K12825 SF3A1, SAP114; splicing factor 3A subunit 1
D K12826 SF3A2, SAP62; splicing factor 3A subunit 2
D K12827 SF3A3, SAP61, PRP9; splicing factor 3A subunit 3
D K12828 SF3B1, SAP155; splicing factor 3B subunit 1
D K12829 SF3B2, SAP145, CUS1; splicing factor 3B subunit 2
D K12830 SF3B3, SAP130, RSE1; splicing factor 3B subunit 3
D K12831 SF3B4, SAP49; splicing factor 3B subunit 4
D K12832 SF3B5, SF3B10; splicing factor 3B subunit 5
D K12833 SF3B14; pre-mRNA branch site protein p14
D K12835 DDX42, SF3B125; ATP-dependent RNA helicase DDX42 [EC:5.6.2.7]
D K12834 PHF5A; PHD finger-like domain-containing protein 5A
C U2 related factors
D K12836 U2AF1; splicing factor U2AF 35 kDa subunit
D K12837 U2AF2; splicing factor U2AF 65 kDa subunit
D K12841 CHERP; calcium homeostasis endoplasmic reticulum protein
D K12820 DHX15, PRP43; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15/PRP43 [EC:5.6.2.6]
D K12811 DDX46, PRP5; ATP-dependent RNA helicase DDX46/PRP5 [EC:5.6.2.7]
D K12838 PUF60; poly(U)-binding-splicing factor PUF60
D K12840 RBM17, SPF45; splicing factor 45
D K12839 SMNDC1, SPF30; survival of motor neuron-related-splicing factor 30
D K12842 SR140; U2-associated protein SR140
D K19604 RP9, PAP-1; retinitis pigmentosa 9 protein
D K24273 ZRSR; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein
B Other components
C Complex A specific factors
D K02180 BUB3; cell cycle arrest protein BUB3
D K08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]
D K13093 HTATSF1; HIV Tat-specific factor 1
D K13094 RBM5_10; RNA-binding protein 5/10
D K13095 SF1; splicing factor 1
D K13096 SF4, SUGP1; splicing factor 4
D K13097 TET1; methylcytosine dioxygenase [EC:1.14.11.80]
D K13098 TLS, FUS; RNA-binding protein FUS
D K24052 RBM20; RNA-binding protein 20
#
AComplex B
B U1 snRNP components
C Sm proteins
D K11086 SNRPB, SMB; small nuclear ribonucleoprotein B and B'
D K11087 SNRPD1, SMD1; small nuclear ribonucleoprotein D1
D K11096 SNRPD2, SMD2; small nuclear ribonucleoprotein D2
D K11088 SNRPD3, SMD3; small nuclear ribonucleoprotein D3
D K11097 SNRPE, SME; small nuclear ribonucleoprotein E
D K11098 SNRPF, SMF; small nuclear ribonucleoprotein F
D K11099 SNRPG, SMG; small nuclear ribonucleoprotein G
C U1 snRNP specific factors
D K11093 SNRP70; U1 small nuclear ribonucleoprotein 70kDa
D K11091 SNRPA; U1 small nuclear ribonucleoprotein A
D K11095 SNRPC; U1 small nuclear ribonucleoprotein C
C U1 related factors
D K12823 DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2 [EC:5.6.2.7]
D K12821 PRPF40, PRP40; pre-mRNA-processing factor 40
D K12822 RBM25, S164; RNA-binding protein 25
D K12824 TCERG1, CA150; transcription elongation regulator 1
B U2 snRNP components
C Sm proteins
D K11086 SNRPB, SMB; small nuclear ribonucleoprotein B and B'
D K11087 SNRPD1, SMD1; small nuclear ribonucleoprotein D1
D K11096 SNRPD2, SMD2; small nuclear ribonucleoprotein D2
D K11088 SNRPD3, SMD3; small nuclear ribonucleoprotein D3
D K11097 SNRPE, SME; small nuclear ribonucleoprotein E
D K11098 SNRPF, SMF; small nuclear ribonucleoprotein F
D K11099 SNRPG, SMG; small nuclear ribonucleoprotein G
C U2 snRNP specific factors
D K11092 SNRPA1; U2 small nuclear ribonucleoprotein A'
D K11094 SNRPB2; U2 small nuclear ribonucleoprotein B''
D K11092 SNRPA1; U2 small nuclear ribonucleoprotein A'
D K11094 SNRPB2; U2 small nuclear ribonucleoprotein B''
D K12825 SF3A1, SAP114; splicing factor 3A subunit 1
D K12826 SF3A2, SAP62; splicing factor 3A subunit 2
D K12827 SF3A3, SAP61, PRP9; splicing factor 3A subunit 3
D K12828 SF3B1, SAP155; splicing factor 3B subunit 1
D K12829 SF3B2, SAP145, CUS1; splicing factor 3B subunit 2
D K12830 SF3B3, SAP130, RSE1; splicing factor 3B subunit 3
D K12831 SF3B4, SAP49; splicing factor 3B subunit 4
D K12832 SF3B5, SF3B10; splicing factor 3B subunit 5
D K12833 SF3B14; pre-mRNA branch site protein p14
D K12835 DDX42, SF3B125; ATP-dependent RNA helicase DDX42 [EC:5.6.2.7]
D K12834 PHF5A; PHD finger-like domain-containing protein 5A
C U2 related factors
D K12836 U2AF1; splicing factor U2AF 35 kDa subunit
D K12837 U2AF2; splicing factor U2AF 65 kDa subunit
D K12841 CHERP; calcium homeostasis endoplasmic reticulum protein
D K12820 DHX15, PRP43; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15/PRP43 [EC:5.6.2.6]
D K12811 DDX46, PRP5; ATP-dependent RNA helicase DDX46/PRP5 [EC:5.6.2.7]
D K12838 PUF60; poly(U)-binding-splicing factor PUF60
D K12840 RBM17, SPF45; splicing factor 45
D K12839 SMNDC1, SPF30; survival of motor neuron-related-splicing factor 30
D K12842 SR140; U2-associated protein SR140
D K19604 RP9, PAP-1; retinitis pigmentosa 9 protein
D K24273 ZRSR; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein
B U4/U6.U5 tri-snRNP components
C Sm proteins
D K11086 SNRPB, SMB; small nuclear ribonucleoprotein B and B'
D K11087 SNRPD1, SMD1; small nuclear ribonucleoprotein D1
D K11096 SNRPD2, SMD2; small nuclear ribonucleoprotein D2
D K11088 SNRPD3, SMD3; small nuclear ribonucleoprotein D3
D K11097 SNRPE, SME; small nuclear ribonucleoprotein E
D K11098 SNRPF, SMF; small nuclear ribonucleoprotein F
D K11099 SNRPG, SMG; small nuclear ribonucleoprotein G
C LSm proteins
D K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
D K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
D K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
D K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
D K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
D K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
D K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
C U4/U6 snRNP specific factors
D K12843 PRPF3, PRP3; U4/U6 small nuclear ribonucleoprotein PRP3
D K12662 PRPF4, PRP4; U4/U6 small nuclear ribonucleoprotein PRP4
D K09567 PPIH, CYPH; peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]
D K12844 PRPF31; U4/U6 small nuclear ribonucleoprotein PRP31
D K12845 SNU13, NHP2L; U4/U6 small nuclear ribonucleoprotein SNU13
D K22611 SART3, TIP110; squamous cell carcinoma antigen recognized by T-cells 3
C U5 snRNP specific factors
D K12852 EFTUD2; 116 kDa U5 small nuclear ribonucleoprotein component
D K12853 SNU114; 114 kDa U5 small nuclear ribonucleoprotein component
D K12855 PRPF6, PRP6; pre-mRNA-processing factor 6
D K12856 PRPF8, PRP8; pre-mRNA-processing factor 8
D K12857 SNRNP40, PRP8BP; Prp8 binding protein
D K12854 SNRNP200, BRR2; pre-mRNA-splicing helicase BRR2 [EC:5.6.2.6]
D K12858 DDX23, PRP28; ATP-dependent RNA helicase DDX23/PRP28 [EC:5.6.2.7]
D K12859 TXNL4A, DIB1; U5 snRNP protein, DIM1 family
D K13099 CD2BP2, PPP1R59; CD2 antigen cytoplasmic tail-binding protein 2
C U4/U6.U5 tri-snRNP specific factors
D K11984 SART1, HAF, SNU66; U4/U6.U5 tri-snRNP-associated protein 1
D K12847 USP39, SAD1; U4/U6.U5 tri-snRNP-associated protein 2
D K12846 SNRNP27; U4/U6.U5 tri-snRNP-associated protein 3
C U4/U6.U5 tri-snRNP related factors
D K12848 SNU23; U4/U6.U5 tri-snRNP component SNU23
D K12849 PRPF38A; pre-mRNA-splicing factor 38A
D K12850 PRPF38B; pre-mRNA-splicing factor 38B
D K12851 PRP38; pre-mRNA-splicing factor 38
D K13100 CWC22; pre-mRNA-splicing factor CWC22
D K12813 DHX16; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:5.6.2.6]
D K13101 GPKOW; G patch domain and KOW motifs-containing protein
D K04455 HSPB1; heat shock protein beta-1
D K10598 PPIL2, CYC4, CHP60; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
D K12598 MTR4, SKIV2L2; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D K12814 PRP2; pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2 [EC:5.6.2.6]
D K13104 ZNF830, CCDC16; zinc finger protein 830
D K19604 RP9, PAP-1; retinitis pigmentosa 9 protein
B Other components
C Prp19 complex
D K10599 PRPF19, PRP19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D K12860 CDC5L, CDC5, CEF1; pre-mRNA-splicing factor CDC5/CEF1
D K12861 BCAS2; pre-mRNA-splicing factor SPF27
D K12862 PLRG1, PRL1, PRP46; pleiotropic regulator 1
D K12863 CWC15; protein CWC15
D K12864 CTNNBL1; beta-catenin-like protein 1
D K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D K12865 PQBP1, NPW38; polyglutamine-binding protein 1
D K12866 WBP11, NPWBP; WW domain-binding protein 11
C Prp19-related factors
D K06063 SNW1, SKIIP, SKIP; SNW domain-containing protein 1
D K12867 SYF1, XAB2; pre-mRNA-splicing factor SYF1
D K12868 SYF2; pre-mRNA-splicing factor SYF2
D K12869 CRN, CRNKL1, CLF1, SYF3; crooked neck
D K12874 AQR; intron-binding protein aquarius
D K12873 BUD31, G10; bud site selection protein 31
D K12871 CCDC12; coiled-coil domain-containing protein 12
D K12870 ISY1; pre-mRNA-splicing factor ISY1
D K09564 PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]
D K12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]
D K13105 PRCC; proline-rich protein PRCC
D K12872 RBM22, SLT11; pre-mRNA-splicing factor RBM22/SLT11
D K25780 KHDC4, BLOM7; kelch domain-containing protein 4
D K27398 CWC2; pre-mRNA-splicing factor CWC2
C RES complex
D K13106 BUD13, CWC26; pre-mRNA-splicing factor CWC26
D K13107 RBMX2, IST3; RNA-binding motif protein, X-linked 2
D K13108 SNIP1; smad nuclear-interacting protein 1
C Complex B specific factors
D K13109 IK, RED, RER; IK cytokine
D K13110 MFAP1; microfibrillar-associated protein 1
D K13111 SMU1; WD40 repeat-containing protein SMU1
D K13112 THRAP3; thyroid hormone receptor-associated protein 3
D K13113 UBL5, HUB1; ubiquitin-like protein 5
#
AComplex C
B U2 snRNP components
C Sm proteins
D K11086 SNRPB, SMB; small nuclear ribonucleoprotein B and B'
D K11087 SNRPD1, SMD1; small nuclear ribonucleoprotein D1
D K11096 SNRPD2, SMD2; small nuclear ribonucleoprotein D2
D K11088 SNRPD3, SMD3; small nuclear ribonucleoprotein D3
D K11097 SNRPE, SME; small nuclear ribonucleoprotein E
D K11098 SNRPF, SMF; small nuclear ribonucleoprotein F
D K11099 SNRPG, SMG; small nuclear ribonucleoprotein G
C LSm proteins
D K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
D K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
C U2 SnRNP specific factors
D K11092 SNRPA1; U2 small nuclear ribonucleoprotein A'
D K11094 SNRPB2; U2 small nuclear ribonucleoprotein B''
D K12825 SF3A1, SAP114; splicing factor 3A subunit 1
D K12826 SF3A2, SAP62; splicing factor 3A subunit 2
D K12827 SF3A3, SAP61, PRP9; splicing factor 3A subunit 3
D K12828 SF3B1, SAP155; splicing factor 3B subunit 1
D K12829 SF3B2, SAP145, CUS1; splicing factor 3B subunit 2
D K12830 SF3B3, SAP130, RSE1; splicing factor 3B subunit 3
D K12831 SF3B4, SAP49; splicing factor 3B subunit 4
D K12832 SF3B5, SF3B10; splicing factor 3B subunit 5
D K12833 SF3B14; pre-mRNA branch site protein p14
D K12835 DDX42, SF3B125; ATP-dependent RNA helicase DDX42 [EC:5.6.2.7]
D K12834 PHF5A; PHD finger-like domain-containing protein 5A
B U4/U6.U5 tri-snRNP components
C Sm proteins
D K11086 SNRPB, SMB; small nuclear ribonucleoprotein B and B'
D K11087 SNRPD1, SMD1; small nuclear ribonucleoprotein D1
D K11096 SNRPD2, SMD2; small nuclear ribonucleoprotein D2
D K11088 SNRPD3, SMD3; small nuclear ribonucleoprotein D3
D K11097 SNRPE, SME; small nuclear ribonucleoprotein E
D K11098 SNRPF, SMF; small nuclear ribonucleoprotein F
D K11099 SNRPG, SMG; small nuclear ribonucleoprotein G
C U5 SnRNP specific factors
D K12852 EFTUD2; 116 kDa U5 small nuclear ribonucleoprotein component
D K12853 SNU114; 114 kDa U5 small nuclear ribonucleoprotein component
D K12854 SNRNP200, BRR2; pre-mRNA-splicing helicase BRR2 [EC:5.6.2.6]
D K12855 PRPF6, PRP6; pre-mRNA-processing factor 6
D K12856 PRPF8, PRP8; pre-mRNA-processing factor 8
D K12857 SNRNP40, PRP8BP; Prp8 binding protein
D K12858 DDX23, PRP28; ATP-dependent RNA helicase DDX23/PRP28 [EC:5.6.2.7]
C U4/U6.U5 tri-SnRNP specific factors
D K11984 SART1, HAF, SNU66; U4/U6.U5 tri-snRNP-associated protein 1
C U4/U6.U5 tri-SnRNP related factors
D K12848 SNU23; U4/U6.U5 tri-snRNP component SNU23
D K12849 PRPF38A; pre-mRNA-splicing factor 38A
D K12850 PRPF38B; pre-mRNA-splicing factor 38B
D K12851 PRP38; pre-mRNA-splicing factor 38
D K13100 CWC22; pre-mRNA-splicing factor CWC22
D K12813 DHX16; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:5.6.2.6]
D K13101 GPKOW; G patch domain and KOW motifs-containing protein
D K04455 HSPB1; heat shock protein beta-1
D K10598 PPIL2, CYC4, CHP60; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
D K12598 MTR4, SKIV2L2; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D K13104 ZNF830, CCDC16; zinc finger protein 830
D K12820 DHX15, PRP43; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15/PRP43 [EC:5.6.2.6]
D K13103 TFIP11; tuftelin-interacting protein 11
D K19604 RP9, PAP-1; retinitis pigmentosa 9 protein
B Other components
C Prp19-CDC5 complex
D K10599 PRPF19, PRP19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D K12860 CDC5L, CDC5, CEF1; pre-mRNA-splicing factor CDC5/CEF1
D K12861 BCAS2; pre-mRNA-splicing factor SPF27
D K12864 CTNNBL1; beta-catenin-like protein 1
D K12863 CWC15; protein CWC15
D K12862 PLRG1, PRL1, PRP46; pleiotropic regulator 1
D K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Prp19-related factors
D K06063 SNW1, SKIIP, SKIP; SNW domain-containing protein 1
D K12867 SYF1, XAB2; pre-mRNA-splicing factor SYF1
D K12868 SYF2; pre-mRNA-splicing factor SYF2
D K12869 CRN, CRNKL1, CLF1, SYF3; crooked neck
D K12874 AQR; intron-binding protein aquarius
D K12873 BUD31, G10; bud site selection protein 31
D K12871 CCDC12; coiled-coil domain-containing protein 12
D K12870 ISY1; pre-mRNA-splicing factor ISY1
D K12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]
D K09564 PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]
D K12872 RBM22, SLT11; pre-mRNA-splicing factor RBM22/SLT11
C RES complex
D K13106 BUD13, CWC26; pre-mRNA-splicing factor CWC26
D K13107 RBMX2, IST3; RNA-binding motif protein, X-linked 2
D K13108 SNIP1; smad nuclear-interacting protein 1
C EJC/TREX
D K12875 ACIN1, ACINUS; apoptotic chromatin condensation inducer in the nucleus
D K12812 DDX39B, UAP56, SUB2; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
D K13025 EIF4A3, FAL1; ATP-dependent RNA helicase [EC:5.6.2.7]
D K25178 CCDC174; coiled-coil domain-containing protein 174
D K12877 MAGOH; protein mago nashi
D K13114 PNN; pinin
D K12876 RBM8A, Y14; RNA-binding protein 8A
D K12878 THOC1; THO complex subunit 1
D K12879 THOC2; THO complex subunit 2
D K12880 THOC3; THO complex subunit 3
D K12881 THOC4, ALY; THO complex subunit 4
C Step II factors
D K12816 CDC40, PRP17; pre-mRNA-processing factor 17
D K12817 PRPF18, PRP18; pre-mRNA-splicing factor 18
D K12819 SLU7; pre-mRNA-processing factor SLU7
D K12818 DHX8, PRP22; ATP-dependent RNA helicase DHX8/PRP22 [EC:5.6.2.6]
D K12815 DHX38, PRP16; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX38/PRP16 [EC:5.6.2.6]
D K24594 RSRC1; arginine/serine-rich coiled-coil protein 1
C PPlases
D K12734 PPIL3; peptidyl-prolyl cis-trans isomerase-like 3 [EC:5.2.1.8]
D K12735 PPIL4; peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8]
D K09566 PPIG; peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8]
D K12736 PPWD1; peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8]
D K12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]
C hnRNP proteins
D K12898 HNRNPF_H; heterogeneous nuclear ribonucleoprotein F/H
D K13161 HNRNPR; heterogeneous nuclear ribonucleoprotein R
D K12895 RALY, HNRNPCL2; RNA-binding protein Raly
C Complex C specific factors
D K13115 CCDC130; coiled-coil domain-containing protein 130
D K13116 DDX41, ABS; ATP-dependent RNA helicase DDX41 [EC:5.6.2.7]
D K13117 DHX35; ATP-dependent RNA helicase DDX35 [EC:5.6.2.6]
D K13118 DGCR14; protein DGCR14
D K13119 FAM50, XAP5; protein FAM50
D K13120 FAM32A; protein FAM32A
D K13121 FRA10AC1; protein FRA10AC1
D K13122 FRG1; protein FRG1
D K13123 GPATCH1; G patch domain-containing protein 1
D K13124 MORG1; mitogen-activated protein kinase organizer 1
D K13125 NOSIP; nitric oxide synthase-interacting protein
D K13126 PABPC; polyadenylate-binding protein
D K13127 RNF113A, CWC24; RING finger protein 113A
D K13103 TFIP11; tuftelin-interacting protein 11
D K13128 ZCCHC8; zinc finger CCHC domain-containing protein 8
D K25058 CACTIN; cactin
D K25059 SDE2; replication stress response regulator SDE2
D K26159 PRKRIP1; PRKR-interacting protein 1
#
AOther splicing related proteins
B Proteins involved in snRNP biogenesis
C SMN complex factors
D K13129 SMN; survival motor neuron protein
D K13130 GEMIN2, SIP1; gem associated protein 2
D K13131 DDX20, GEMIN3; ATP-dependent RNA helicase DDX20 [EC:5.6.2.7]
D K13132 GEMIN4; gem associated protein 4
D K13133 GEMIN5; gem associated protein 5
D K13134 GEMIN6, SIP2; gem associated protein 6
D K13135 GEMIN7, SIP3; gem associated protein 7
D K13136 GEMIN8; gem associated protein 8
D K13137 STRAP, UNRIP; serine-threonine kinase receptor-associated protein
C Integrator complex
D K13138 INTS1; integrator complex subunit 1
D K13139 INTS2; integrator complex subunit 2
D K13140 INTS3; integrator complex subunit 3
D K13141 INTS4; integrator complex subunit 4
D K13142 INTS5; integrator complex subunit 5
D K13143 INTS6, DDX26; integrator complex subunit 6
D K13144 INTS7; integrator complex subunit 7
D K13145 INTS8; integrator complex subunit 8
D K13146 INTS9; integrator complex subunit 9
D K13147 INTS10; integrator complex subunit 10
D K13148 CPSF3L, INTS11; integrator complex subunit 11 [EC:3.1.27.-]
D K13149 INTS12; integrator complex subunit 12
C Other proteins involved in snRNP biogenesis
D K13150 COIL, CLN80; coilin
D K12839 SMNDC1, SPF30; survival of motor neuron-related-splicing factor 30
D K13151 SNUPN, RNUT1; snurportin-1
D K23093 USB1; U6 snRNA phosphodiesterase [EC:3.1.4.-]
D K05019 CLNS1A; chloride channel, nucleotide-sensitive, 1A
D K14292 TGS1; trimethylguanosine synthase [EC:2.1.1.-]
D K13180 INTS6L, DDX26B; integrator complex subunit 6-like
D K06874 ZPR1; zinc finger protein ZPR1
B Minor spliceosome components
C Minor spliceosome specific factors
D K13152 ZMAT5; U11/U12 small nuclear ribonucleoprotein 20 kDa protein
D K13153 SNRNP25; U11/U12 small nuclear ribonucleoprotein 25 kDa protein
D K13154 ZCRB1; U11/U12 small nuclear ribonucleoprotein 31 kDa protein
D K13155 SNRNP35; U11/U12 small nuclear ribonucleoprotein 35 kDa protein
D K13156 SNRNP48; U11/U12 small nuclear ribonucleoprotein 48 kDa protein
D K13157 RNPC3; U11/U12 small nuclear ribonucleoprotein 65 kDa protein
C Minor spliceosome associated proteins
D K24824 RBM48; RNA-binding protein 48
D K24825 ARMC7; armadillo repeat-containing protein 7
D K24826 CRIPT; cysteine-rich PDZ-binding protein
D K24827 SCNM1; sodium channel modifier 1
D K10598 PPIL2, CYC4, CHP60; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
D K26160 CENATAC; centrosomal AT-AC splicing factor
B Spliceosome associated proteins (SAPs)
C hnRNP proteins
D K12894 HNRNPA0; heterogeneous nuclear ribonucleoprotein A0
D K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
D K13044 HNRNPABD; heterogeneous nuclear ribonucleoprotein A/B/D
D K13159 HNRNPL; heterogeneous nuclear ribonucleoprotein L
D K13160 SYNCRIP, HNRNPQ; heterogeneous nuclear ribonucleoprotein Q
D K13162 PCBP2; poly(rC)-binding protein 2
D K13163 MSL1; male-specific lethal 1
D K13164 MSL2; male-specific lethal 2
D K03102 SQD; squid
C SR proteins
D K12899 SRSF11, SFRS11; serine/arginine-rich splicing factor 11
D K13165 SREK1, SFRS12; splicing regulatory glutamine/lysine-rich protein 1
D K13166 SUGP2, SFRS14; SURP and G-patch domain-containing protein 2
D K13167 SCAF4, SFRS15; SR-related and CTD-associated factor 4
D K13168 CLASRP, SFRS16; CLK4-associating serine/arginine rich protein
D K13169 AKAP17, SFRS17; A-kinase anchor protein 17
D K13170 PNISR, SFRS18; arginine/serine-rich protein PNISR
D K25101 SRSF12; serine/arginine-rich splicing factor 12
C SR-related proteins
D K13171 SRRM1, SRM160; serine/arginine repetitive matrix protein 1
D K13172 SRRM2, SRM300; serine/arginine repetitive matrix protein 2
D K13173 ARGLU1; arginine and glutamate-rich protein 1
D K23718 SON; protein SON
D K25057 PSIP1, LEDGF; PC4 and SFRS1-interacting protein
D K25781 ILDR1; immunoglobulin-like domain-containing receptor 1
D K25782 ILDR2; immunoglobulin-like domain-containing receptor 2
D K26076 ZRANB2; zinc finger Ran-binding domain-containing protein 2
C TREX complex
D K12878 THOC1; THO complex subunit 1
D K12879 THOC2; THO complex subunit 2
D K12880 THOC3; THO complex subunit 3
D K12881 THOC4, ALY; THO complex subunit 4
D K13174 THOC5; THO complex subunit 5
D K13175 THOC6; THO complex subunit 6
D K13176 THOC7; THO complex subunit 7
D K12812 DDX39B, UAP56, SUB2; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
C RNA helicase-like proteins
D K13177 DDX1; ATP-dependent RNA helicase DDX1 [EC:5.6.2.7]
D K11594 DDX3X, bel; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
D K17642 DDX3Y; ATP-dependent RNA helicase DDX3Y [EC:5.6.2.7]
D K13178 DDX17; ATP-dependent RNA helicase DDX17 [EC:5.6.2.7]
D K13179 DDX18, HAS1; ATP-dependent RNA helicase DDX18/HAS1 [EC:5.6.2.7]
D K13181 DDX27, DRS1; ATP-dependent RNA helicase DDX27 [EC:5.6.2.7]
D K13182 DDX39; ATP-dependent RNA helicase DDX39 [EC:5.6.2.7]
D K17043 DDX43; ATP-dependent RNA helicase DDX43 [EC:5.6.2.7]
D K13183 DDX50; ATP-dependent RNA helicase DDX50 [EC:5.6.2.7]
D K13184 DHX9; ATP-dependent RNA/DNA helicase DHX9 [EC:5.6.2.6 5.6.2.4]
D K13185 DHX30; ATP-dependent RNA helicase DHX30 [EC:5.6.2.6]
D K18994 DHX32; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 [EC:5.6.2.6]
D K20099 YTHDC2; ATP-dependent RNA helicase YTHDC2 [EC:5.6.2.6]
D K26077 ISE2, EMB25; ATP-dependent RNA helicase ISE2 [EC:5.6.2.6]
D K14433 DQX1; ATP-dependent helicase [EC:5.6.2.-]
C RNA binding proteins (RBPs)
D K13186 RBM3; RNA-binding protein 3
D K13187 RBM4; RNA-binding protein 4
D K13188 RBM7; RNA-binding protein 7
D K25005 RBM11; splicing regulator RBM11
D K24526 RBM12; RNA-binding protein 12
D K13189 RBM14; RNA-binding protein 14
D K13190 RBM15; RNA-binding protein 15
D K13191 RBM16, SCAF8; RNA-binding protein 16
D K24527 RBM18; RNA-binding protein 18
D K25006 RBM24_38; RNA-binding protein 24/38
D K13192 RBM26; RNA-binding protein 26
D K13193 RBM27; RNA-binding protein 27
D K25090 RBMY1; RNA-binding motif protein, Y chromosome, family 1
D K25091 RBPMS; RNA-binding protein with multiple splicing
D K12968 ADAR, ADAR1; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
D K13194 ADARB; double stranded RNA-specific editase B [EC:3.5.-.-]
D K11586 CBX3, HP1G; chromobox protein 3
D K13195 CIRBP; cold-inducible RNA-binding protein
D K06099 CSDA, ZONAB; cold shock domain protein A
D K13196 DPF2, REQ; zinc finger protein ubi-d4
D K17391 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1
D K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
D K13198 KHDRBS1; KH domain-containing, RNA-binding, signal transduction-associated protein 1
D K17843 KHDRBS2, SLM1; KH domain-containing, RNA-binding, signal transduction-associated protein 2
D K14942 KHDRBS3, SLM2; KH domain-containing, RNA-binding, signal transduction-associated protein 3
D K14943 MBNL; muscleblind
D K14944 NOVA; RNA-binding protein Nova
D K14945 QKI; protein quaking
D K14946 RBFOX, FOX; RNA binding protein fox-1
D K13199 SERBP1; plasminogen activator inhibitor 1 RNA-binding protein
D K13200 STRBP; spermatid perinuclear RNA-binding protein
D K13201 TIA1, TIAL1; nucleolysin TIA-1/TIAR
D K13202 TOE1; target of EGR1 protein 1
D K13203 ZFR; zinc finger RNA-binding protein
D K13204 ZNF326; zinc finger protein 326
D K20100 YTHDC1; YTH domain-containing protein 1
D K25931 NKAP; NF-kappa-B-activating protein
C Other SAPs
D K13205 AAR2, C20orf4; A1 cistron-splicing factor AAR2
D K13206 CCDC55; coiled-coil domain-containing protein 55
D K23561 CLK1_4; dual specificity protein kinase CLK1/4 [EC:2.7.12.1]
D K08823 CLK2_3; dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
D K13207 CUGBP, BRUNOL, CELF; CUG-BP- and ETR3-like factor
D K02177 BRU; bruno
D K09526 DNAJC6; DnaJ homolog subfamily C member 6
D K09528 DNAJC8; DnaJ homolog subfamily C member 8
D K09533 DNAJC13; DnaJ homolog subfamily C member 13
D K13208 ELAVL2_3_4; ELAV like protein 2/3/4
D K14947 ESRP1_2; epithelial splicing regulatory protein 1/2
D K13209 EWSR1; RNA-binding protein EWS
D K13210 FUBP; far upstream element-binding protein
D K13211 GCFC; GC-rich sequence DNA-binding factor
D K13212 LUC7L2; RNA-binding protein Luc7-like 2
D K13213 MATR3; matrin 3
D K13214 NONO, NRB54; non-POU domain-containing octamer-binding protein
D K24993 PSPC1; paraspeckle component 1
D K13219 SFPQ, PSF; splicing factor, proline- and glutamine-rich
D K13215 NRIP2; nuclear receptor-interacting protein 2
D K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
D K13216 PPP1R8, NIPP1; nuclear inhibitor of protein phosphatase 1 [EC:3.1.4.-]
D K02516 PRMT5, HSL7; type II protein arginine methyltransferase [EC:2.1.1.320]
D K08827 PRPF4B; serine/threonine-protein kinase PRP4 [EC:2.7.11.1]
D K13217 PRPF39, PRP39; pre-mRNA-processing factor 39
D K24999 RAVER1; ribonucleoprotein PTB-binding 1
D K13218 PTBP1, PTB; polypyrimidine tract-binding protein 1
D K14948 PTBP2, NPTB; polypyrimidine tract-binding protein 2
D K17844 PTBP3, ROD1; polypyrimidine tract-binding protein 3
D K15409 SRPK1; serine/threonine-protein kinase SRPK1 [EC:2.7.11.1]
D K08831 SRPK2; serine/threonine-protein kinase SRPK2 [EC:2.7.11.1]
D K10884 XRCC6, KU70, G22P1; ATP-dependent DNA helicase 2 subunit 1
D K13220 WBP4, FBP21; WW domain-binding protein 4
D K13221 WDR77, MEP50; methylosome protein 50
D K23966 CCNL; cyclin L
D K18328 DBR1; lariat debranching enzyme [EC:3.1.-.-]
D K24939 CWF19L1, DRN1; CWF19-like protein 1
D K24940 CWF19L2; CWF19-like protein 2
D K25092 SAFB; scaffold attachment factor B
#
ASplicing related RNAs
B K14276 U1snRNA; U1 spliceosomal RNA
B K14277 U2snRNA; U2 spliceosomal RNA
B K14278 U4snRNA; U4 spliceosomal RNA
B K14279 U5snRNA; U5 spliceosomal RNA
B K14280 U6snRNA; U6 spliceosomal RNA
B K26388 RNU4ATAC; U4 atac small nuclear RNA
B K26387 RNU6ATAC; U6atac small nuclear RNA
B K27200 SNORD7; small nucleolar RNA SNORD7
B K27201 SNORD8_9; small nucleolar RNA SNORD8/9
B K27206 SNORD10; small nucleolar RNA SNORD10
B K26386 SNORD115; small nucleolar RNA SNORD115
B K27152 SCARNA1, ACA35; small Cajal body-specific RNA 1
B K27161 SCARNA2; small Cajal body-specific RNA 2
B K27153 SCARNA4, ACA26; small Cajal body-specific RNA 4
B K27154 SCARNA6, SCARNA5; small Cajal body-specific RNA 6
B K27166 SCARNA7, U90; small Cajal body-specific RNA 7
B K27167 SCARNA8, U92; small Cajal body-specific RNA 8
B K27168 SCARNA9; small Cajal body-specific RNA 9
B K27155 SCARNA10, U85; small Cajal body-specific RNA 10
B K27156 SCARNA11, ACA57; small Cajal body-specific RNA 11
B K27157 SCARNA12, U89; small Cajal body-specific RNA 12
B K27169 SCARNA13, U93; small Cajal body-specific RNA 13
B K27170 SCARNA14, U100; small Cajal body-specific RNA 14
B K27158 SCARNA15, ACA45; small Cajal body-specific RNA 15
B K27159 SCARNA16, ACA47; small Cajal body-specific RNA 16
B K27171 SCARNA17, U91; small Cajal body-specific RNA 17
B K27172 SCARNA18, U109; small Cajal body-specific RNA 18
B K27160 SCARNA24, SCARNA23; small Cajal body-specific RNA 24
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 15, 2024