+C Peptidoglycan biosynthesis and degradation proteins KO
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Peptidoglycan Biosynthesis and Degradation Proteins - Mycobacterium ulcerans
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APrecursor biosynthesis
B Transferase/Dehydrogenase
C MUL_3950 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
C MUL_4552 murB; UDP-N-acetylenolpyruvoylglucosamine reductase MurB K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
B Amino acid ligase
C MUL_3500 murC; UDP-N-acetylmuramate-alanine ligase MurC K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
C MUL_3503 murD; UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
C MUL_3506 murE; UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase MurE K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
C MUL_1976 ddlA; d-alanine--D-alanine ligase DdlA K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
B Racemase
C MUL_0879 alr; alanine racemase, Alr K01775 alr; alanine racemase [EC:5.1.1.1]
C MUL_3925 murI; glutamate racemase MurI K01776 murI; glutamate racemase [EC:5.1.1.3]
B Carboxypeptidase
B Glycosyltransferase
C MUL_3504 murX; phospho-N-acetylmuramoyl-pentappeptidetransferase MurX K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
C MUL_3501 murG; UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol-N-acetylglucosamine transferase MurG K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
B Diphosphatase
C MUL_2366 conserved transmembrane protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
B Flippase
C MUL_5063 conserved transmembrane protein K03980 murJ; putative peptidoglycan lipid II flippase
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APeptidoglycan biosynthesis and degradation
B Glycosyltransferase/DD-Transpeptidase (Class A PBP)
B DD-Transpeptidase (Class B PBP)
C MUL_3508 pbpB; penicillin-binding membrane protein PbpB K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
C MUL_0020 pbpA; penicillin-binding protein PbpA K05364 pbpA; penicillin-binding protein A
B DD-Carboxypeptidase/DD-Endopeptidase (Low molecular weight PBP)
C MUL_2045 dacB; D-alanyl-D-alanine carboxypeptidase DacB K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C MUL_1445 dacC; penicillin-binding protein DacC K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C MUL_4203 dacB1; D-alanyl-D-alanine carboxypeptidase DacB1 K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
B Glycosyltransferase
B Transpeptidase
B Carboxypeptidase
C MUL_0369 lpqR; conserved lipoprotein, LpqR K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
B Endopeptidase
C MUL_3545 conserved hypothetical secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
C MUL_1486 cell wall-associated hydrolase K21473 ripA; peptidoglycan DL-endopeptidase RipA [EC:3.4.-.-]
C MUL_1487 inv2; invasion protein Inv2 K21474 ripB; peptidoglycan DL-endopeptidase RipB [EC:3.4.-.-]
B Sortase
B Lytic transglycosylase
C MUL_1756 conserved membrane protein K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]
B Amidase
C MUL_4308 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
C MUL_5068 hydrolase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
B Structural protein
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: January 30, 2024