+D Chaperone KO
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Chaperones and Folding Catalysts - Acanthamoeba castellanii
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AHeat shock proteins
B HSP110
C ACA1_175260 DnaK family superfamily protein K09486 HYOU1; hypoxia up-regulated 1
C ACA1_266970 DnaK family superfamily protein K09486 HYOU1; hypoxia up-regulated 1
B HSP100
C ACA1_369850 ATPase with chaperone activity, putative K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
B HSP90
C ACA1_205660 heat shock protein 82, putative K04079 HSP90A; molecular chaperone HtpG
C ACA1_205910 heat shock protein 90 alpha, putative K04079 HSP90A; molecular chaperone HtpG
C ACA1_058840 heat shock protein gp96, putative K09487 HSP90B; heat shock protein 90kDa beta
C ACA1_053660 TNF receptor-associated protein 1, putative K09488 TRAP1; TNF receptor-associated protein 1
B HSP70 / DNAK
C ACA1_387860 high molecular weight heat shock protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C ACA1_374380 heat shock protein ssa1, putative K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C ACA1_367360 DnaK family superfamily protein K09489 HSPA4; heat shock 70kDa protein 4
C ACA1_320840 HSP91 (Heat shock protein 91), putative K09489 HSPA4; heat shock 70kDa protein 4
C ACA1_096310 DnaK family protein K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
C ACA1_055970 chaperone protein dnak, putative K04043 dnaK; molecular chaperone DnaK
C ACA1_058850 chaperone protein DnaK, putative K04043 dnaK; molecular chaperone DnaK
B HSP60 / Chaperonin
C ACA1_064700 Tcomplex protein 1, gamma subunit K09495 CCT3; T-complex protein 1 subunit gamma
C ACA1_290270 Tcomplex protein 1, delta subunit K09496 CCT4; T-complex protein 1 subunit delta
C ACA1_292900 Tcomplex protein 1, epsilon subunit K09497 CCT5; T-complex protein 1 subunit epsilon
C ACA1_059740 Tcomplex protein 1, eta subunit K09499 CCT7; T-complex protein 1 subunit eta
C ACA1_090030 Tcomplex protein 1, theta subunit K09500 CCT8; T-complex protein 1 subunit theta
C ACA1_128510 chaperonin GroL, putative K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
B HSP47
B HSP40 / DNAJ
C ACA1_174130 Hsp40, putative K09503 DNAJA2; DnaJ homolog subfamily A member 2
C ACA1_322570 Hsp40, putative K09503 DNAJA2; DnaJ homolog subfamily A member 2
C ACA1_313740 Fbox domain containing protein K09503 DNAJA2; DnaJ homolog subfamily A member 2
C ACA1_145260 DnaJ domain containing protein K09506 DNAJA5; DnaJ homolog subfamily A member 5
C ACA1_070460 chaperone protein DnaJ, putative K09510 DNAJB4; DnaJ homolog subfamily B member 4
C ACA1_207970 Myblike DNA-binding domain containing protein K09522 DNAJC2; DnaJ homolog subfamily C member 2
C ACA1_208090 DnaJ domain containing protein K09522 DNAJC2; DnaJ homolog subfamily C member 2
C ACA1_048650 Hsp40, putative K09527 DNAJC7; DnaJ homolog subfamily C member 7
C ACA1_153070 DnaJ domain containing protein K09528 DNAJC8; DnaJ homolog subfamily C member 8
C ACA1_206360 DnaJ domain containing protein K09529 DNAJC9; DnaJ homolog subfamily C member 9
C ACA1_073420 chaperone protein DnaJ, putative K09531 DNAJC11; DnaJ homolog subfamily C member 11
C ACA1_193270 DnaJ domain containing protein K09532 DNAJC12; DnaJ homolog subfamily C member 12
C ACA1_112070 DnaJ K09537 DNAJC17; DnaJ homolog subfamily C member 17
C ACA1_181530 translocase of the inner mitochondrial membrane 14 isoform a, putative K09539 DNAJC19; DnaJ homolog subfamily C member 19
C ACA1_251300 DnaJ domain containing protein K19371 DNAJC25; DnaJ homolog subfamily C member 25
C ACA1_221030 hypothetical protein K19373 DNAJC28; DnaJ homolog subfamily C member 28
C ACA1_290880 chaperone protein DnaJ, putative K03686 dnaJ; molecular chaperone DnaJ
C ACA1_057830 FeS protein assembly co-chaperone HscB, putative K04082 hscB; molecular chaperone HscB
B HSP33
B HSP24
B HSP20
C ACA1_164110 hypothetical protein K13993 HSP20; HSP20 family protein
B HSP15
B HSP10
B GimC
C ACA1_145220 prefoldin subunit 2, putative K09549 PFDN2; prefoldin subunit 2
C ACA1_396130 prefoldin, alpha subunit K04797 pfdA; prefoldin alpha subunit
C ACA1_265270 Prefoldin subunit 6, putative K04798 pfdB; prefoldin beta subunit
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AOther chaperones and cochaperones
B Calnexin / calreticulin
C ACA1_142350 calreticulin, putative K08057 CALR; calreticulin
B DegP / HtrA
B AAA proteases
C ACA1_040710 ATP-dependent metallopeptidase HflB subfamily protein K08956 AFG3; AFG3 family protein [EC:3.4.24.-]
C ACA1_107270 ATPdependent metallopeptidase HflB subfamily protein K08956 AFG3; AFG3 family protein [EC:3.4.24.-]
B PapD
B SecB
B Sti1 / p60
C ACA1_074970 stressinducible protein STI1-like, putative K09553 STIP1; stress-induced-phosphoprotein 1
B Cdc37 / p50
B BAG
B Others
C ACA1_253180 ARM repeat fold domain containing protein K09562 HSPBP1; hsp70-interacting protein
C ACA1_062190 hypothetical protein K23327 HIKESHI; protein Hikeshi
C ACA1_208280 hypothetical protein K21804 METTL21A; protein N-lysine methyltransferase METTL21A [EC:2.1.1.-]
C ACA1_045300 nicotinamide n-methyltransferase K21804 METTL21A; protein N-lysine methyltransferase METTL21A [EC:2.1.1.-]
C ACA1_128520 hypothetical protein K23151 METTL23; methyltransferase-like protein 23 [EC:2.1.1.-]
C ACA1_112910 tetratricopeptide repeat domain containing protein K16365 SGTA; small glutamine-rich tetratricopeptide repeat-containing protein alpha
C ACA1_399210 tetratricopeptide repeat domain containing protein K24927 TTC4; tetratricopeptide repeat protein 4
C ACA1_369880 hypothetical protein K24962 CCDC47; PAT complex subunit CCDC47
C ACA1_072810 Activator of Hsp90 atpase, putative K26216 AHSA1; activator of Hsp90 ATPase protein 1
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AIntramolecular chaperones
B Subtilisin family
C ACA1_264710 membranebound transcription factor protease, site 1 isoform 1, putative K08653 MBTPS1; membrane-bound transcription factor site-1 protease [EC:3.4.21.112]
C ACA1_234230 peptidase, S8/S53 subfamily protein K01349 FURIN; furin [EC:3.4.21.75]
C ACA1_101480 Prokumamolisin, activation domain containing protein K01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]
C ACA1_098270 Prokumamolisin, activation domain containing protein K01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]
C ACA1_321740 Prokumamolisin, activation domain containing protein K01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]
C ACA1_200110 Prokumamolisin, activation domain containing protein K01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]
C ACA1_087870 Tripeptidylpeptidase 1, putative K01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]
C ACA1_154200 Prokumamolisin, activation domain containing protein K01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]
C ACA1_153950 sedolisinlike peptidase K01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]
C ACA1_077970 Prokumamolisin, activation domain containing protein K01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]
C ACA1_157540 Prokumamolisin, activation domain containing protein K01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]
C ACA1_020120 Prokumamolisin, activation domain containing protein K01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]
C ACA1_109090 Prokumamolisin, putative K01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]
C ACA1_149240 peptidase, S8/S53 subfamily protein K01280 TPP2; tripeptidyl-peptidase II [EC:3.4.14.10]
B Papain family
C ACA1_159080 papain family cysteine protease subfamily protein K01363 CTSB; cathepsin B [EC:3.4.22.1]
C ACA1_198340 papain family cysteine protease subfamily protein K01363 CTSB; cathepsin B [EC:3.4.22.1]
C ACA1_051490 Cysteine proteinase 5, putative K01365 CTSL; cathepsin L [EC:3.4.22.15]
C ACA1_125110 cysteine proteinase K01365 CTSL; cathepsin L [EC:3.4.22.15]
C ACA1_155530 Cathepsin L precursor (Cysteine proteinase 1), putative K01365 CTSL; cathepsin L [EC:3.4.22.15]
C ACA1_270350 papain family cysteine protease containing protein K01365 CTSL; cathepsin L [EC:3.4.22.15]
C ACA1_317670 cathepsin L, putative K01365 CTSL; cathepsin L [EC:3.4.22.15]
C ACA1_198270 papain family cysteine protease subfamily protein K01365 CTSL; cathepsin L [EC:3.4.22.15]
C ACA1_115390 cysteine proteinase K01365 CTSL; cathepsin L [EC:3.4.22.15]
C ACA1_066290 papain family cysteine protease subfamily protein K01365 CTSL; cathepsin L [EC:3.4.22.15]
C ACA1_018960 papain family cysteine protease subfamily protein K01365 CTSL; cathepsin L [EC:3.4.22.15]
C ACA1_138380 cathepsin Llike cysteine protease K01365 CTSL; cathepsin L [EC:3.4.22.15]
C ACA1_181520 cathepsin L, putative K01365 CTSL; cathepsin L [EC:3.4.22.15]
B Other peptidases
C ACA1_057490 zinc carboxypeptidase superfamily protein K08779 CPA1; carboxypeptidase A1 [EC:3.4.17.1]
C ACA1_290560 carboxypeptidase A3, putative K08779 CPA1; carboxypeptidase A1 [EC:3.4.17.1]
B Others
C ACA1_318090 glycosyl hydrolase family 20, catalytic domain containing protein K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C ACA1_360350 glycosyl hydrolase family 20, catalytic domain containing protein K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C ACA1_218390 glycosyl hydrolase family 20, catalytic domain containing protein K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
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AProtein folding catalysts
B Peptidyl prolyl isomerase
C Cyclophilin
D ACA1_326230 peptidylprolyl cis-trans isomerase, cyclophilin-type domain containing protein K09566 PPIG; peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8]
D ACA1_035380 peptidylprolyl isomerase H, putative K09567 PPIH; peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]
D ACA1_313600 Peptidylprolyl cis-trans isomerase-like 1, putative K12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]
D ACA1_287510 peptidylprolyl isomeraselike 2, putative K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
D ACA1_282960 peptidylprolyl cis-trans isomerase, cyclophilin-type domain containing protein K12735 PPIL4; peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8]
D ACA1_053670 CYP, putative K12736 PPWD1; peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8]
D ACA1_067830 peptidylprolyl cis-trans isomerase, putative K12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]
C FKBP
D ACA1_260230 peptidylprolyl cis-trans isomerase, FKBP-type domain containing protein K09568 FKBP1; FK506-binding protein 1 [EC:5.2.1.8]
D ACA1_258560 hypothetical protein K09570 FKBP3; FK506-binding protein 3 [EC:5.2.1.8]
D ACA1_383630 peptidylprolyl cis-trans isomerase, FKBP-type domain containing protein K09571 FKBP4_5; FK506-binding protein 4/5 [EC:5.2.1.8]
C Parvulin
D ACA1_061250 parvulintype peptidyl-prolyl cis/trans isomerase K09579 PIN4; peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [EC:5.2.1.8]
B Protein disulfide isomerase
C ACA1_235540 thioredoxin domain containing protein K03671 TXN; thioredoxin
C ACA1_218400 thioredoxin domain containing protein K03671 TXN; thioredoxin
C ACA1_246790 thioredoxin-1, putative K03671 TXN; thioredoxin
C ACA1_065240 glutaredoxin, putative K03676 grxC; glutaredoxin 3
C ACA1_126440 glutaredoxin, putative K07390 grxD; monothiol glutaredoxin
C ACA1_267190 thioredoxin domain containing protein K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
C ACA1_374120 protein disulfideisomerase domain containing protein K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
C ACA1_374090 protein disulfideisomerase domain containing protein K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
C ACA1_305150 protein disulfide isomerase associated 4, putative K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
C ACA1_074740 thioredoxin domain containing protein K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C ACA1_040460 Protein disulfideisomerase, putative K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C ACA1_248630 thioredoxin domain containing protein K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C ACA1_044740 hypothetical protein K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C ACA1_189420 protein disulfideisomerase domain containing protein K13984 TXNDC5; thioredoxin domain-containing protein 5 [EC:5.3.4.1]
C ACA1_069020 thioredoxin domain containing protein K13984 TXNDC5; thioredoxin domain-containing protein 5 [EC:5.3.4.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: January 25, 2024