+D GENES KO
#
KEGG Orthology (KO) - Acidithiobacillus ferrooxidans ATCC 23270
%
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:afr00010]
D AFE_2841 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
D AFE_2924 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D AFE_1807 carbohydrate kinase, PfkB family K16370 pfkB; 6-phosphofructokinase 2 [EC:2.7.1.11]
D AFE_0189 fbp; fructose-1-6-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D AFE_3253 glpX; fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D AFE_3248 fba; fructose-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D AFE_1676 fructose-bisphosphate aldolase class II family protein K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D AFE_1802 fructose-bisphosphate aldolase, putative K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D AFE_2633 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D AFE_3251 gap; glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D AFE_3250 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D AFE_0526 gpmI-2; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D AFE_1815 gpmI-1; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D AFE_0849 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D AFE_0749 pyruvate kinase barrel domain protein K00873 PK; pyruvate kinase [EC:2.7.1.40]
D AFE_1801 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D AFE_3249 pykA; pyruvate kinase II K00873 PK; pyruvate kinase [EC:2.7.1.40]
D AFE_1816 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D AFE_1813 dehydrogenase complex, E1 component, alpha subunit, putative K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D AFE_3070 pdhA; pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D AFE_1812 dehydrogenase complex, E1 component, beta subunit, putative K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D AFE_3069 pdhB; pyruvate dehydrogenase, E1 component, pyruvate dehydrogenase beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D AFE_1811 2-oxo acid dehydrogenase, acyltransferase, putative K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D AFE_1893 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_3068 pdhC; pyruvate dehydrogenase complex, E2 and E3 components K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_0958 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_0697 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D AFE_2088 zinc-binding alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D AFE_0846 alcohol dehydrogenase, zinc-containing K13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
D AFE_1981 PQQ enzyme repeat protein K00114 exaA; alcohol dehydrogenase (cytochrome c) [EC:1.1.2.8]
D AFE_2131 aldehyde dehydrogenase (NAD) family protein K00138 aldB; aldehyde dehydrogenase [EC:1.2.1.-]
D AFE_1742 aldehyde dehydrogenase (NAD) family protein K00138 aldB; aldehyde dehydrogenase [EC:1.2.1.-]
D AFE_1969 acs; acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D AFE_2324 phosphoglucomutase, putative K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
C 00020 Citrate cycle (TCA cycle) [PATH:afr00020]
D AFE_3065 citZ; citrate synthase II K01647 CS; citrate synthase [EC:2.3.3.1]
D AFE_0423 aconitate hydratase, putative K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D AFE_0424 icd; isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D AFE_1893 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_3068 pdhC; pyruvate dehydrogenase complex, E2 and E3 components K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_0958 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_0427 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D AFE_0425 sucC; succinyl-CoA synthase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D AFE_2673 fumC; fumarate hydratase, class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D AFE_3000 lactate/malate dehydrogenase family protein K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D AFE_1813 dehydrogenase complex, E1 component, alpha subunit, putative K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D AFE_3070 pdhA; pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D AFE_1812 dehydrogenase complex, E1 component, beta subunit, putative K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D AFE_3069 pdhB; pyruvate dehydrogenase, E1 component, pyruvate dehydrogenase beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D AFE_1811 2-oxo acid dehydrogenase, acyltransferase, putative K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
C 00030 Pentose phosphate pathway [PATH:afr00030]
D AFE_2924 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D AFE_2025 zwf; glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D AFE_2833 pgl; 6-phosphogluconolactonase K01057 PGLS; 6-phosphogluconolactonase [EC:3.1.1.31]
D AFE_2024 6-phosphogluconate dehydrogenase family protein K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D AFE_3247 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D AFE_1843 tkt-1; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D AFE_3252 tkt-2; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D AFE_0419 tal; transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D AFE_0629 rpiA; ribose 5-phosphate isomerase A K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D AFE_2053 xfp; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase K01621 xfp; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22]
D AFE_2324 phosphoglucomutase, putative K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D AFE_2286 PhnN protein, putative K05774 phnN; ribose 1,5-bisphosphokinase [EC:2.7.4.23]
D AFE_2766 prsA; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D AFE_2225 glucose 1-dehydrogenase, putative K00034 gdh; glucose 1-dehydrogenase [EC:1.1.1.47]
D AFE_1857 glucose 1-dehydrogenase, putative K00034 gdh; glucose 1-dehydrogenase [EC:1.1.1.47]
D AFE_3248 fba; fructose-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D AFE_1676 fructose-bisphosphate aldolase class II family protein K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D AFE_1802 fructose-bisphosphate aldolase, putative K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D AFE_0189 fbp; fructose-1-6-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D AFE_3253 glpX; fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D AFE_1807 carbohydrate kinase, PfkB family K16370 pfkB; 6-phosphofructokinase 2 [EC:2.7.1.11]
C 00040 Pentose and glucuronate interconversions [PATH:afr00040]
D AFE_1343 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D AFE_1405 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D AFE_0618 UDP-glucose/GDP-mannose dehydrogenase family protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D AFE_0445 galU; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D AFE_3247 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
C 00051 Fructose and mannose metabolism [PATH:afr00051]
D AFE_1550 carbohydrate kinase, PfkB family K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D AFE_1366 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
D AFE_3293 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
D AFE_2960 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
D AFE_0943 phosphomannomutase, putative K01840 manB; phosphomannomutase [EC:5.4.2.8]
D AFE_3292 gmd-2; GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]
D AFE_2977 gmd-1; GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]
D AFE_1807 carbohydrate kinase, PfkB family K16370 pfkB; 6-phosphofructokinase 2 [EC:2.7.1.11]
D AFE_0189 fbp; fructose-1-6-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D AFE_3253 glpX; fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D AFE_3248 fba; fructose-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D AFE_1676 fructose-bisphosphate aldolase class II family protein K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D AFE_1802 fructose-bisphosphate aldolase, putative K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D AFE_2633 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D AFE_3291 NAD-dependent epimerase/dehydratase family protein K15856 rmd; GDP-4-dehydro-6-deoxy-D-mannose reductase [EC:1.1.1.281]
D AFE_3020 PTS system, IIA component, putative K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
C 00052 Galactose metabolism [PATH:afr00052]
D AFE_1342 galE; UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D AFE_2322 conserved hypothetical protein K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D AFE_0445 galU; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D AFE_2324 phosphoglucomutase, putative K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D AFE_2841 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
D AFE_1807 carbohydrate kinase, PfkB family K16370 pfkB; 6-phosphofructokinase 2 [EC:2.7.1.11]
C 00053 Ascorbate and aldarate metabolism [PATH:afr00053]
D AFE_1343 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D AFE_1405 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D AFE_0618 UDP-glucose/GDP-mannose dehydrogenase family protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D AFE_0609 NAD-dependent epimerase/dehydratase family protein K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]
D AFE_1966 NAD-dependent epimerase/dehydratase family protein K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]
C 00500 Starch and sucrose metabolism [PATH:afr00500]
D AFE_1551 sucrose phosphate synthase K00696 E2.4.1.14; sucrose-phosphate synthase [EC:2.4.1.14]
D AFE_1552 sucrose synthase, putative K00695 SUS; sucrose synthase [EC:2.4.1.13]
D AFE_0445 galU; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D AFE_2838 glgC; glucose-1-phosphate adenylyltransferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]
D AFE_2678 glgA; glycogen synthase K00703 glgA; starch synthase [EC:2.4.1.21]
D AFE_2836 glgB; 1,4-alpha-glucan branching enzyme K00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]
D AFE_0527 glycogen/starch/alpha-glucan phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
D AFE_1799 alpha-glucan phosphorylase family protein K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
D AFE_2482 cga; glucan 1,4-alpha-glucosidase K01178 SGA1; glucoamylase [EC:3.2.1.3]
D AFE_2224 glycosyl hydrolase, family 15 K01178 SGA1; glucoamylase [EC:3.2.1.3]
D AFE_2840 glycosyl hydrolase, family 57 K22451 jgt; 4-alpha-glucanotransferase [EC:2.4.1.25]
D AFE_2081 alpha-amylase family protein K06044 treY; (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase [EC:5.4.99.15]
D AFE_2082 alpha-amylase family protein K01236 treZ; maltooligosyltrehalose trehalohydrolase [EC:3.2.1.141]
D AFE_2083 glycosyl transferase, group 1 K13057 treT; trehalose synthase [EC:2.4.1.245]
D AFE_2324 phosphoglucomutase, putative K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D AFE_2841 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
D AFE_2924 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D AFE_1550 carbohydrate kinase, PfkB family K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:afr00520]
D AFE_2825 nagZ; beta-hexosaminidase K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]
D AFE_1550 carbohydrate kinase, PfkB family K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D AFE_3200 glmS; glucosamine--fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D AFE_2634 glmM; phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D AFE_3201 glmU; UDP-N-acetylglucosamine pyrophosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
D AFE_0181 conserved hypothetical protein K09001 anmK; anhydro-N-acetylmuramic acid kinase [EC:2.7.1.170]
D AFE_1823 gph-1; phosphoglycolate phosphatase K22292 mupP; N-acetyl-D-muramate 6-phosphate phosphatase [EC:3.1.3.105]
D AFE_3033 phosphotransferase, putative K07102 amgK; N-acetylmuramate 1-kinase [EC:2.7.1.221]
D AFE_3032 nucleotidyltransferase family protein K00992 murU; N-acetyl-alpha-D-muramate 1-phosphate uridylyltransferase [EC:2.7.7.99]
D AFE_3039 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D AFE_0204 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D AFE_2841 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
D AFE_2324 phosphoglucomutase, putative K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D AFE_0445 galU; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D AFE_1343 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D AFE_1405 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D AFE_0618 UDP-glucose/GDP-mannose dehydrogenase family protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D AFE_1342 galE; UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D AFE_2322 conserved hypothetical protein K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D AFE_0609 NAD-dependent epimerase/dehydratase family protein K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]
D AFE_1966 NAD-dependent epimerase/dehydratase family protein K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]
D AFE_3020 PTS system, IIA component, putative K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D AFE_2924 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D AFE_0943 phosphomannomutase, putative K01840 manB; phosphomannomutase [EC:5.4.2.8]
D AFE_1366 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
D AFE_3293 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
D AFE_2960 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
D AFE_3292 gmd-2; GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]
D AFE_2977 gmd-1; GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]
D AFE_3291 NAD-dependent epimerase/dehydratase family protein K15856 rmd; GDP-4-dehydro-6-deoxy-D-mannose reductase [EC:1.1.1.281]
D AFE_1540 aminotransferase, DegT/DnrJ/EryC1/StrS family K13010 per; perosamine synthetase [EC:2.6.1.102]
D AFE_0252 CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3-dehydrase reductase, putative K00523 ascD; CDP-4-dehydro-6-deoxyglucose reductase, E3 [EC:1.17.1.1]
D AFE_0860 iron-sulfur cluster-binding protein/oxidoreductase, FAD/NAD-binding K00523 ascD; CDP-4-dehydro-6-deoxyglucose reductase, E3 [EC:1.17.1.1]
D AFE_2838 glgC; glucose-1-phosphate adenylyltransferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]
C 00620 Pyruvate metabolism [PATH:afr00620]
D AFE_1969 acs; acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D AFE_1813 dehydrogenase complex, E1 component, alpha subunit, putative K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D AFE_3070 pdhA; pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D AFE_1812 dehydrogenase complex, E1 component, beta subunit, putative K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D AFE_3069 pdhB; pyruvate dehydrogenase, E1 component, pyruvate dehydrogenase beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D AFE_1811 2-oxo acid dehydrogenase, acyltransferase, putative K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D AFE_1893 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_3068 pdhC; pyruvate dehydrogenase complex, E2 and E3 components K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_0958 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_2088 zinc-binding alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D AFE_0697 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D AFE_0846 alcohol dehydrogenase, zinc-containing K13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
D AFE_1981 PQQ enzyme repeat protein K00114 exaA; alcohol dehydrogenase (cytochrome c) [EC:1.1.2.8]
D AFE_1810 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D AFE_0749 pyruvate kinase barrel domain protein K00873 PK; pyruvate kinase [EC:2.7.1.40]
D AFE_1801 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D AFE_3249 pykA; pyruvate kinase II K00873 PK; pyruvate kinase [EC:2.7.1.40]
D AFE_1462 accA; acetyl-CoA carboxylase, carboxyl transferase, alpha subunit K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D AFE_0196 accB; acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D AFE_0195 accC; acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D AFE_2067 accD; acetyl-CoA carboxylase, carboxyl transferase, beta subunit K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D AFE_2131 aldehyde dehydrogenase (NAD) family protein K00138 aldB; aldehyde dehydrogenase [EC:1.2.1.-]
D AFE_1742 aldehyde dehydrogenase (NAD) family protein K00138 aldB; aldehyde dehydrogenase [EC:1.2.1.-]
D AFE_3161 D-isomer specific 2-hydroxyacid dehydrogenase family protein K03778 ldhA; D-lactate dehydrogenase [EC:1.1.1.28]
D AFE_0402 gloA; lactoylglutathione lyase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
D AFE_0397 hydroxyacylglutathione hydrolase, putative K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D AFE_0660 malic enzyme family protein K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D AFE_3000 lactate/malate dehydrogenase family protein K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D AFE_2673 fumC; fumarate hydratase, class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D AFE_1883 ppc; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D AFE_1816 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D AFE_2596 leuA-1; 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D AFE_1989 leuA-2; 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D AFE_1506 nifV; homocitrate synthase K02594 nifV; homocitrate synthase NifV [EC:2.3.3.14]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:afr00630]
D AFE_1969 acs; acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D AFE_3000 lactate/malate dehydrogenase family protein K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D AFE_3065 citZ; citrate synthase II K01647 CS; citrate synthase [EC:2.3.3.1]
D AFE_0423 aconitate hydratase, putative K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D AFE_1665 glcD; glycolate oxidase, subunit GlcD K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14]
D AFE_1664 glcE; glycolate oxidase, subunit GlcE K11472 glcE; glycolate dehydrogenase FAD-binding subunit [EC:1.1.99.14]
D AFE_1663 glcF; glycolate oxidase, iron-sulfur subunit K11473 glcF; glycolate dehydrogenase iron-sulfur subunit [EC:1.1.99.14]
D AFE_2218 HAD-superfamily hydrolase, subfamily IA K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D AFE_3246 gph-2; phosphoglycolate phosphatase K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D AFE_1691 cbbL-2; ribulose bisphosphate carboxylase, large subunit K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D AFE_2155 cbbL2; ribulose bisphosphate carboxylase, large subunit 2 K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D AFE_3051 cbbL-1; ribulose bisphosphate carboxylase, large subunit K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D AFE_1690 cbbS-2; ribulose bisphosphate carboxylase, small subunit K01602 rbcS; ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39]
D AFE_3052 cbbS-1; ribulose bisphosphate carboxylase, small subunit K01602 rbcS; ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39]
D AFE_0466 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D AFE_0295 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D AFE_0981 gcvP; glycine dehydrogenase, decarboxylating K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D AFE_0982 glycine dehydrogenase (decarboxylating), subunit 2 K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D AFE_0979 gcvT; glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D AFE_1893 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_3068 pdhC; pyruvate dehydrogenase complex, E2 and E3 components K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_0958 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_2869 glycine cleavage system H protein, putative K02437 gcvH; glycine cleavage system H protein
D AFE_0980 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D AFE_2549 glycine cleavage system protein H, putative K02437 gcvH; glycine cleavage system H protein
D AFE_2547 glycine cleavage system H protein, putative K02437 gcvH; glycine cleavage system H protein
C 00640 Propanoate metabolism [PATH:afr00640]
D AFE_1969 acs; acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D AFE_1810 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D AFE_1893 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_3068 pdhC; pyruvate dehydrogenase complex, E2 and E3 components K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_0958 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_1462 accA; acetyl-CoA carboxylase, carboxyl transferase, alpha subunit K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D AFE_0196 accB; acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D AFE_0195 accC; acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D AFE_2067 accD; acetyl-CoA carboxylase, carboxyl transferase, beta subunit K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D AFE_0425 sucC; succinyl-CoA synthase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D AFE_0427 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
C 00650 Butanoate metabolism [PATH:afr00650]
D AFE_1808 phosphate acetyl/butyryl transferase K00634 ptb; phosphate butyryltransferase [EC:2.3.1.19]
D AFE_1546 succinate-semialdehyde dehydrogenase, putative K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D AFE_0745 ilvB; acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D AFE_0746 ilvN; acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
C 00660 C5-Branched dibasic acid metabolism [PATH:afr00660]
D AFE_0745 ilvB; acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D AFE_0746 ilvN; acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D AFE_0425 sucC; succinyl-CoA synthase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D AFE_0427 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D AFE_0624 leuC; 3-isopropylmalate dehydratase, large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D AFE_0626 leuD; 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D AFE_2075 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
C 00562 Inositol phosphate metabolism [PATH:afr00562]
D AFE_3254 inositol monophosphatase family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D AFE_0669 inositol monophosphate family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D AFE_2633 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:afr00190]
D AFE_2630 nuoA; NADH-quinone oxidoreductase, A subunit K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D AFE_2411 NADH-quinone oxidoreductase, B subunit K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D AFE_2629 nuoB; NADH-quinone oxidoreductase, B subunit K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D AFE_2628 nuoC; NADH-quinone oxidoreductase, C subunit K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]
D AFE_2627 nuoD; NADH-quinone oxidoreductase, D subunit K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]
D AFE_2626 nuoE; NADH-quinone oxidoreductase, E subunit K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]
D AFE_2625 nuoF; NADH-quinone oxidoreductase, F subunit K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]
D AFE_2624 nuoG; NADH-quinone oxidoreductase, G subunit K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2]
D AFE_2623 nuoH; NADH-quinone oxidoreductase, H subunit K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D AFE_2622 nuoI; NADH-quinone oxidoreductase, I subunit K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D AFE_2621 nuoJ; NADH-quinone oxidoreductase, J subunit K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D AFE_2620 nuoK; NADH-quinone oxidoreductase, K subunit K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D AFE_2619 nuoL; NADH-quinone oxidoreductase, L subunit K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D AFE_2618 nuoM; NADH-quinone oxidoreductase, M subunit K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
D AFE_2617 nuoN; NADH-quinone oxidoreductase, N subunit K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D AFE_1854 pyridine nucleotide-disulfide oxidoreductase K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
D AFE_2729 petA-2; ubiquinol--cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D AFE_3109 petA-1; ubiquinol--cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D AFE_2730 petB-2; ubiquinol--cytochrome c reductase, cytochrome b subunit K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D AFE_3110 petB-1; ubiquinol--cytochrome c reductase, cytochrome b subunit K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D AFE_3111 petC-1; ubiquinol--cytochrome c reductase, cytochrome c1 subunit K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
D AFE_2731 petC-2; ubiquinol--cytochrome c reductase, cytochrome c1 subunit K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
D AFE_0635 cyoE-1; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D AFE_3143 cyoE-2; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D AFE_0634 cyoD; cytochrome o ubiquinol oxidase, subunit IV K02300 cyoD; cytochrome o ubiquinol oxidase subunit IV
D AFE_3148 coxC; cytochrome c oxidase, aa3-type, subunit III K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]
D AFE_3149 coxA; cytochrome c oxidase, aa3-type, subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D AFE_3150 coxB; cytochrome c oxidase, aa3-type, subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D AFE_0633 cyoC; cytochrome o ubiquinol oxidase, subunit III K02299 cyoC; cytochrome o ubiquinol oxidase subunit III
D AFE_0632 cyoB; cytochrome o ubiquinol oxidase, subunit I K02298 cyoB; cytochrome o ubiquinol oxidase subunit I [EC:7.1.1.3]
D AFE_0631 cyoA; cytochrome o ubiquinol oxidase, subunit II K02297 cyoA; cytochrome o ubiquinol oxidase subunit II [EC:7.1.1.3]
D AFE_0955 cydA; cytochrome d ubiquinol oxidase, subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D AFE_0954 cydB; cytochrome d ubiquinol oxidase, subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D AFE_1962 cytochrome c family protein K08738 CYC; cytochrome c
D AFE_2450 cytochrome c family protein K08738 CYC; cytochrome c
D AFE_3205 atpA; ATP synthase F1, alpha subunit K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D AFE_3203 atpD; ATP synthase F1, beta subunit K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D AFE_3204 atpG; ATP synthase F1, gamma subunit K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D AFE_3206 atpH; ATP synthase F1, delta subunit K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D AFE_3202 atpC; ATP synthase F1, epsilon subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D AFE_2423 ATP synthase F1, epsilon subunit, putative K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D AFE_0758 ATP synthase F1, epsilon subunit, putative K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D AFE_3209 atpB; ATP synthase F0, A subunit K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D AFE_3207 atpF; ATP synthase F0, B subunit K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D AFE_3208 atpE; ATP synthase F0, C subunit K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D AFE_3086 plasma-membrane proton-efflux P-type ATPase, putative K01535 PMA1; H+-transporting ATPase [EC:7.1.2.1]
D AFE_0818 plasma-membrane proton-efflux P-type ATPase K01535 PMA1; H+-transporting ATPase [EC:7.1.2.1]
D AFE_0492 ppa; inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
D AFE_1876 ppk; polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
D AFE_1892 conserved hypothetical protein K22468 ppk2; polyphosphate kinase [EC:2.7.4.34]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation in photosynthetic organisms [PATH:afr00710]
D AFE_1691 cbbL-2; ribulose bisphosphate carboxylase, large subunit K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D AFE_2155 cbbL2; ribulose bisphosphate carboxylase, large subunit 2 K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D AFE_3051 cbbL-1; ribulose bisphosphate carboxylase, large subunit K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D AFE_1690 cbbS-2; ribulose bisphosphate carboxylase, small subunit K01602 rbcS; ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39]
D AFE_3052 cbbS-1; ribulose bisphosphate carboxylase, small subunit K01602 rbcS; ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39]
D AFE_3250 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D AFE_3251 gap; glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D AFE_3248 fba; fructose-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D AFE_1676 fructose-bisphosphate aldolase class II family protein K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D AFE_0189 fbp; fructose-1-6-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D AFE_3253 glpX; fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D AFE_1843 tkt-1; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D AFE_3252 tkt-2; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D AFE_0629 rpiA; ribose 5-phosphate isomerase A K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D AFE_0536 cbbP; phosphoribulokinase K00855 PRK; phosphoribulokinase [EC:2.7.1.19]
D AFE_2633 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D AFE_3247 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D AFE_1883 ppc; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D AFE_0660 malic enzyme family protein K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D AFE_3000 lactate/malate dehydrogenase family protein K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00720 Carbon fixation pathways in prokaryotes
C 00680 Methane metabolism [PATH:afr00680]
D AFE_0696 gfa; S-(hydroxymethyl)glutathione synthase K03396 gfa; S-(hydroxymethyl)glutathione synthase [EC:4.4.1.22]
D AFE_0697 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D AFE_0698 fghA; S-formylglutathione hydrolase K01070 frmB; S-formylglutathione hydrolase [EC:3.1.2.12]
D AFE_0295 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D AFE_0849 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D AFE_1883 ppc; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D AFE_3000 lactate/malate dehydrogenase family protein K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D AFE_3248 fba; fructose-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D AFE_1676 fructose-bisphosphate aldolase class II family protein K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D AFE_1802 fructose-bisphosphate aldolase, putative K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D AFE_0189 fbp; fructose-1-6-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D AFE_3253 glpX; fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D AFE_1807 carbohydrate kinase, PfkB family K16370 pfkB; 6-phosphofructokinase 2 [EC:2.7.1.11]
D AFE_2553 pyridine nucleotide-disulfide oxidoreductase K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D AFE_2554 heterodisulfide reductase subunit B, homolog K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D AFE_2586 heterodisulfide reductase subunit B, homolog K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D AFE_2550 sdhC; succinate dehydrogenase/fumarate reductase, C subunit K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D AFE_2555 iron-sulfur cluster-binding protein K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D AFE_2551 iron-sulfur cluster-binding protein K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D AFE_1810 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D AFE_1969 acs; acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D AFE_1816 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D AFE_0526 gpmI-2; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D AFE_1815 gpmI-1; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D AFE_0896 serA; D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D AFE_0895 serC; phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
D AFE_0368 serB; phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 00910 Nitrogen metabolism [PATH:afr00910]
D AFE_1521 nifD; nitrogenase molybdenum-iron protein, alpha subunit K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1]
D AFE_1520 nifK; nitrogenase molybdenum-iron protein, beta subunit K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]
D AFE_1522 nifH; nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH
D AFE_1657 hybrid cluster protein K05601 hcp; hydroxylamine reductase [EC:1.7.99.1]
D AFE_0466 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D AFE_0730 gltB; glutamate synthase, large subunit K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
D AFE_0729 gltD; glutamate synthase, small subunit K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]
D AFE_0287 carbonic anhydrase K01673 cynT; carbonic anhydrase [EC:4.2.1.1]
C 00920 Sulfur metabolism [PATH:afr00920]
D AFE_2971 cysNC; sulfate adenylate transferase, large subunit/adenylylsulfate kinase K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
D AFE_3125 cysN; sulfate adenylyltransferase, large subunit K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
D AFE_2970 cysD-1; sulfate adenylyltransferase, small subunit K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D AFE_3124 cysD-2; sulfate adenylyltransferase, small subunit K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D AFE_0539 sulfate adenylyltransferase, putative/adenylylsulfate kinase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D AFE_2973 cysQ; 3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
D AFE_3123 cysH; adenylylsulfate reductase, thioredoxin dependent K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D AFE_3121 cysJ; sulfite reductase (NADPH) flavoprotein, alpha component K00380 cysJ; sulfite reductase (NADPH) flavoprotein alpha-component [EC:1.8.1.2]
D AFE_3122 cysI; sulfite reductase (NADPH) hemoprotein beta-component K00381 cysI; sulfite reductase (NADPH) hemoprotein beta-component [EC:1.8.1.2]
D AFE_1792 sulfide-quinone reductase, putative K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D AFE_0267 sqr; sulfide quinone reductase, putative K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D AFE_2601 pyridine nucleotide-disulfide oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D AFE_3118 pyridine nucleotide-disulfide oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D AFE_0956 metallo-beta-lactamase family protein K17725 ETHE1; sulfur dioxygenase [EC:1.13.11.18]
D AFE_0044 doxD_2; DoxD-like family protein K05908 doxDA; thiosulfate dehydrogenase (quinone) [EC:1.8.5.2]
D AFE_0048 doxD_1; DoxD-like family protein K05908 doxDA; thiosulfate dehydrogenase (quinone) [EC:1.8.5.2]
D AFE_0671 cysE-2; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D AFE_1505 cysE-1; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D AFE_0293 metX; homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D AFE_2063 metZ; O-succinylhomoserine sulfhydrylase K10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:afr00061]
D AFE_1462 accA; acetyl-CoA carboxylase, carboxyl transferase, alpha subunit K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D AFE_0196 accB; acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D AFE_0195 accC; acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D AFE_2067 accD; acetyl-CoA carboxylase, carboxyl transferase, beta subunit K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D AFE_0797 acyl carrier protein, putative K02078 acpP; acyl carrier protein
D AFE_1909 acpP; acyl carrier protein K02078 acpP; acyl carrier protein
D AFE_1907 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D AFE_1906 fabH; 3-oxoacyl-(acyl-carrier-protein) synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D AFE_0796 3-oxoacyl-(acyl-carrier-protein) synthase, putative K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]
D AFE_1910 fabF; 3-oxoacyl-(acyl-carrier-protein) synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D AFE_0793 3-oxoacyl-(acyl-carrier-protein) reductase, putative K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D AFE_1908 fabG; 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D AFE_1455 fabZ; beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D AFE_0420 fabI; enoyl-(acyl-carrier-protein) reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D AFE_0220 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:afr00071]
D AFE_0220 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D AFE_0859 pyridine nucleotide-disulfide oxidoreductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3]
D AFE_0697 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D AFE_2088 zinc-binding alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:afr00561]
D AFE_0846 alcohol dehydrogenase, zinc-containing K13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
D AFE_1905 plsX; fatty acid/phospholipid synthesis protein PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D AFE_0125 membrane protein, putative K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D AFE_0058 acyltransferase family protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D AFE_2584 acyltransferase family protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D AFE_1427 glycosyl transferase, group 1 family protein K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]
C 00564 Glycerophospholipid metabolism [PATH:afr00564]
D AFE_2126 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
D AFE_0125 membrane protein, putative K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D AFE_0058 acyltransferase family protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D AFE_2584 acyltransferase family protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D AFE_0594 phosphatidylethanolamine N-methyltransferase, putative K00570 pmtA; phosphatidylethanolamine/phosphatidyl-N-methylethanolamine N-methyltransferase [EC:2.1.1.17 2.1.1.71]
D AFE_1449 cdsA; phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]
D AFE_0750 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferse K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
D AFE_0748 psd; phosphatidylserine decarboxylase K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]
D AFE_0854 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
D AFE_0929 pgpA; phosphatidylglycerophosphatase A K01095 pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27]
D AFE_1740 phospholipase D family protein K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-]
D AFE_0278 phospholipase D family protein K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-]
D AFE_1900 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, putative K08744 CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41]
D AFE_2544 geranylgeranyl reductase family protein K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
D AFE_2121 glycosyl transferase, group 2 family protein K00720 UGCG; ceramide glucosyltransferase [EC:2.4.1.80]
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:afr00230]
D AFE_2324 phosphoglucomutase, putative K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D AFE_2766 prsA; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D AFE_2064 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D AFE_2261 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D AFE_1896 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D AFE_2023 purT; phosphoribosylglycinamide formyltransferase 2 K08289 purT; phosphoribosylglycinamide formyltransferase 2 [EC:6.3.1.21]
D AFE_2354 purL; phosphoribosylformylglycinamidine synthase K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
D AFE_1897 purM; phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D AFE_0273 purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D AFE_0272 purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D AFE_2355 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D AFE_2356 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D AFE_2260 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D AFE_0540 adenine phosphoribosyltransferase, putative K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D AFE_0468 surE; acid phosphatase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D AFE_0403 conserved hypothetical protein K09913 ppnP; purine/pyrimidine-nucleoside phosphorylase [EC:2.4.2.1 2.4.2.2]
D AFE_0432 conserved hypothetical protein TIGR00726 K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D AFE_0364 hypoxanthine-guanine phosphoribosyltransferase, putative K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
D AFE_1777 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D AFE_1929 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D AFE_2341 rdgB; non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D AFE_0809 oxidoreductase, molybdopterin binding subunit K11177 yagR; xanthine dehydrogenase YagR molybdenum-binding subunit [EC:1.17.1.4]
D AFE_0808 oxidoreductase, FAD-binding subunit K11178 yagS; xanthine dehydrogenase YagS FAD-binding subunit [EC:1.17.1.4]
D AFE_0810 oxidoreductase, iron-sulfur subunit K13483 yagT; xanthine dehydrogenase YagT iron-sulfur-binding subunit
D AFE_1778 guaA; GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D AFE_2530 conserved hypothetical protein K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D AFE_0772 guanine deaminase, putative K01487 guaD; guanine deaminase [EC:3.5.4.3]
D AFE_0563 gmk; guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8]
D AFE_2638 nrdA; ribonucleotide-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D AFE_2639 nrdB; ribonucleoside-diphosphate reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D AFE_2718 nrdD; anaerobic ribonucleoside-triphosphate reductase, alpha subunit K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D AFE_0731 deoxyguanosinetriphosphate triphosphohydrolase, putative K01129 dgt; dGTPase [EC:3.1.5.1]
D AFE_0565 spoT; guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D AFE_1441 ppx; exopolyphosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
D AFE_1889 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D AFE_0530 carbohydrate kinase, PfkB family K00856 ADK; adenosine kinase [EC:2.7.1.20]
D AFE_0773 add; adenosine deaminase K21053 ade; adenine deaminase [EC:3.5.4.2]
D AFE_2139 conserved hypothetical protein TIGR00282 K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]
D AFE_0348 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D AFE_2193 apaH; bis(5-nucleosyl)-tetraphosphatase (symmetrical) K01525 apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [EC:3.6.1.41]
D AFE_2971 cysNC; sulfate adenylate transferase, large subunit/adenylylsulfate kinase K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
D AFE_3125 cysN; sulfate adenylyltransferase, large subunit K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
D AFE_2970 cysD-1; sulfate adenylyltransferase, small subunit K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D AFE_3124 cysD-2; sulfate adenylyltransferase, small subunit K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D AFE_0539 sulfate adenylyltransferase, putative/adenylylsulfate kinase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D AFE_0778 conserved domain protein K01483 allA; ureidoglycolate lyase [EC:4.3.2.3]
D AFE_0785 ggt; gamma-glutamyltranspeptidase K22602 hpxW; oxamate amidohydrolase [EC:3.5.1.126]
C 00240 Pyrimidine metabolism [PATH:afr00240]
D AFE_0639 carB; carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D AFE_0640 carA; carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D AFE_3059 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D AFE_1672 dihydroorotase, homodimeric type K01465 URA4; dihydroorotase [EC:3.5.2.3]
D AFE_1463 pyrC-2; dihydroorotase, multifunctional complex type K01465 URA4; dihydroorotase [EC:3.5.2.3]
D AFE_3058 pyrC-1; dihydroorotase, multifunctional complex type K01465 URA4; dihydroorotase [EC:3.5.2.3]
D AFE_2264 pyrD; dihydroorotate dehydrogenase K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2]
D AFE_0908 pyrE; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D AFE_0907 pyrF; orotidine 5`-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D AFE_1446 pyrH; uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D AFE_1929 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D AFE_2953 maf-1; maf protein K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]
D AFE_0847 pyrG; CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D AFE_0902 cmk; cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D AFE_0468 surE; acid phosphatase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D AFE_0403 conserved hypothetical protein K09913 ppnP; purine/pyrimidine-nucleoside phosphorylase [EC:2.4.2.1 2.4.2.2]
D AFE_3060 pyrR; PyrR bifunctional protein K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]
D AFE_2139 conserved hypothetical protein TIGR00282 K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]
D AFE_2718 nrdD; anaerobic ribonucleoside-triphosphate reductase, alpha subunit K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D AFE_2660 dcd; deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D AFE_2638 nrdA; ribonucleotide-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D AFE_2639 nrdB; ribonucleoside-diphosphate reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D AFE_1913 tmk; thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D AFE_0356 dut; deoxyuridine 5`-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D AFE_0732 thyX; thymidylate synthase, flavin-dependent K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:afr00250]
D AFE_2022 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D AFE_1392 nadB; L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D AFE_1353 asnB; asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D AFE_0404 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D AFE_3277 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D AFE_1889 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D AFE_2356 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D AFE_3059 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D AFE_1546 succinate-semialdehyde dehydrogenase, putative K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D AFE_0730 gltB; glutamate synthase, large subunit K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
D AFE_0729 gltD; glutamate synthase, small subunit K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]
D AFE_0466 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D AFE_0639 carB; carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D AFE_0640 carA; carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D AFE_3200 glmS; glucosamine--fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D AFE_2064 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:afr00260]
D AFE_0407 aspartate kinase, monofunctional class K00928 lysC; aspartate kinase [EC:2.7.2.4]
D AFE_2074 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D AFE_0473 metM; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D AFE_3097 thrB; homoserine kinase K02204 thrB2; homoserine kinase type II [EC:2.7.1.39]
D AFE_0474 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D AFE_0295 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D AFE_0526 gpmI-2; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D AFE_1815 gpmI-1; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D AFE_0896 serA; D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D AFE_0895 serC; phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
D AFE_0368 serB; phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D AFE_0981 gcvP; glycine dehydrogenase, decarboxylating K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D AFE_0982 glycine dehydrogenase (decarboxylating), subunit 2 K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D AFE_0979 gcvT; glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D AFE_1893 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_3068 pdhC; pyruvate dehydrogenase complex, E2 and E3 components K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_0958 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_2869 glycine cleavage system H protein, putative K02437 gcvH; glycine cleavage system H protein
D AFE_0980 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D AFE_2549 glycine cleavage system protein H, putative K02437 gcvH; glycine cleavage system H protein
D AFE_2547 glycine cleavage system H protein, putative K02437 gcvH; glycine cleavage system H protein
D AFE_0750 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferse K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
D AFE_0722 ilvA; threonine ammonia-lyase, biosynthetic K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D AFE_2068 trpA; tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D AFE_2069 trpB; tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
C 00270 Cysteine and methionine metabolism [PATH:afr00270]
D AFE_0671 cysE-2; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D AFE_1505 cysE-1; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D AFE_0239 aminotransferase, class II K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D AFE_0288 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D AFE_0532 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D AFE_0157 s-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50]
D AFE_2160 conserved hypothetical protein K00797 speE; spermidine synthase [EC:2.5.1.16]
D AFE_0150 conserved hypothetical protein K00797 speE; spermidine synthase [EC:2.5.1.16]
D AFE_0156 speE; spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16]
D AFE_1999 autoinducer synthesis protein K13061 rhlI; acyl homoserine lactone synthase [EC:2.3.1.184]
D AFE_2123 MTA/SAH nucleosidase, putative K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9]
D AFE_0432 conserved hypothetical protein TIGR00726 K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D AFE_1826 amidohydrolase family protein K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D AFE_0365 mtaP; methylthioadenosine phosphorylase K19696 mtiP; 5'-methylthioinosine phosphorylase [EC:2.4.2.44]
D AFE_0893 eiF2B; translation initiation factor, putative, aIF-2BI family K08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23]
D AFE_0436 aldolase, class II K08964 mtnB; methylthioribulose-1-phosphate dehydratase [EC:4.2.1.109]
D AFE_0434 ccbL2; ribulose bisphosphate carboxylase, large subunit 2 K08965 mtnW; 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [EC:5.3.2.5]
D AFE_0435 HAD-superfamily hydrolase, subfamily IB K08966 mtnX; 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [EC:3.1.3.87]
D AFE_0433 dioxygenase, ARD/ARD' family K08967 mtnD; 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase [EC:1.13.11.53 1.13.11.54]
D AFE_0534 ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D AFE_0407 aspartate kinase, monofunctional class K00928 lysC; aspartate kinase [EC:2.7.2.4]
D AFE_2074 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D AFE_0473 metM; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D AFE_0293 metX; homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D AFE_2063 metZ; O-succinylhomoserine sulfhydrylase K10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-]
D AFE_0547 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D AFE_3064 gshA; glutamate--cysteine ligase K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2]
D AFE_3063 gshB; glutathione synthetase K01920 gshB; glutathione synthase [EC:6.3.2.3]
D AFE_2022 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D AFE_3000 lactate/malate dehydrogenase family protein K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D AFE_2832 cysM; cysteine synthase B K12339 cysM; S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) [EC:2.5.1.144]
D AFE_0896 serA; D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D AFE_0895 serC; phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
C 00280 Valine, leucine and isoleucine degradation [PATH:afr00280]
D AFE_0547 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D AFE_1893 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_3068 pdhC; pyruvate dehydrogenase complex, E2 and E3 components K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_0958 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:afr00290]
D AFE_0722 ilvA; threonine ammonia-lyase, biosynthetic K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D AFE_0624 leuC; 3-isopropylmalate dehydratase, large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D AFE_0626 leuD; 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D AFE_2075 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D AFE_0745 ilvB; acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D AFE_0746 ilvN; acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D AFE_0747 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D AFE_0662 ilvD-2; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D AFE_1673 ilvD-1; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D AFE_0547 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D AFE_2596 leuA-1; 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D AFE_1989 leuA-2; 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00300 Lysine biosynthesis [PATH:afr00300]
D AFE_0473 metM; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D AFE_0407 aspartate kinase, monofunctional class K00928 lysC; aspartate kinase [EC:2.7.2.4]
D AFE_2074 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D AFE_2358 dapA; dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D AFE_2663 dapB; dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D AFE_1820 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]
D AFE_0406 argD; acetylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D AFE_1821 aminotransferase, classes I and II K14267 dapC; N-succinyldiaminopimelate aminotransferase [EC:2.6.1.17]
D AFE_1819 dapE; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D AFE_2743 dapF; diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D AFE_3279 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D AFE_0211 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D AFE_0210 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
C 00310 Lysine degradation [PATH:afr00310]
D AFE_1893 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_3068 pdhC; pyruvate dehydrogenase complex, E2 and E3 components K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_0958 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_1546 succinate-semialdehyde dehydrogenase, putative K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D AFE_0720 FAD-dependent oxidoreductase K26064 amaD; D-lysine oxidase
C 00220 Arginine biosynthesis [PATH:afr00220]
D AFE_0405 argF; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D AFE_0404 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D AFE_3277 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D AFE_0466 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D AFE_2022 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D AFE_0664 argA; N-acetylglutamate synthase K14682 argAB; amino-acid N-acetyltransferase [EC:2.3.1.1]
D AFE_0226 argJ; arginine biosynthesis bifunctional protein ArgJ K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]
D AFE_0256 argB; acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8]
D AFE_3073 argC; N-acetyl-gamma-glutamyl-phosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]
D AFE_0406 argD; acetylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
C 00330 Arginine and proline metabolism [PATH:afr00330]
D AFE_1471 speA; arginine decarboxylase K01585 speA; arginine decarboxylase [EC:4.1.1.19]
D AFE_2526 hydrolase, carbon-nitrogen family K12251 aguB; N-carbamoylputrescine amidase [EC:3.5.1.53]
D AFE_2160 conserved hypothetical protein K00797 speE; spermidine synthase [EC:2.5.1.16]
D AFE_0150 conserved hypothetical protein K00797 speE; spermidine synthase [EC:2.5.1.16]
D AFE_0156 speE; spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16]
D AFE_0157 s-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50]
D AFE_0262 proC; pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]
D AFE_0281 proB-3; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D AFE_1783 proB-2; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D AFE_2464 proB-1; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D AFE_2238 amino acid kinase family protein K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D AFE_0454 proA; gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
D AFE_1210 oxidoreductase, 2OG-Fe(II) oxygenase family K00472 P4HA; prolyl 4-hydroxylase [EC:1.14.11.2]
D AFE_3138 oxidoreductase, 2OG-Fe(II) oxygenase family K00472 P4HA; prolyl 4-hydroxylase [EC:1.14.11.2]
D AFE_2022 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00340 Histidine metabolism [PATH:afr00340]
D AFE_3040 hisG; ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D AFE_1888 hisZ; ATP phosphoribosyltransferase regulatory subunit K02502 hisZ; ATP phosphoribosyltransferase regulatory subunit
D AFE_3047 hisIE; phosphoribosyl-AMP pyrophosphatase/phosphoribosyl-ATP cyclohydrolase K11755 hisIE; phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31]
D AFE_3045 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D AFE_3044 hisH; imidazole glycerol phosphate synthase, glutamine amidotransferase subunit K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D AFE_3046 hisF; imidazoleglycerol phosphate synthase, cyclase subunit K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D AFE_3043 hisB; imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
D AFE_0898 hisC-2; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D AFE_3042 hisC-1; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D AFE_3041 hisD; histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
C 00350 Tyrosine metabolism [PATH:afr00350]
D AFE_2022 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D AFE_0898 hisC-2; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D AFE_3042 hisC-1; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D AFE_0697 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D AFE_2088 zinc-binding alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D AFE_1546 succinate-semialdehyde dehydrogenase, putative K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D AFE_1472 fumarylacetoacetate hydrolase family protein K16165 nagK; fumarylpyruvate hydrolase [EC:3.7.1.20]
C 00360 Phenylalanine metabolism [PATH:afr00360]
D AFE_2022 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D AFE_0898 hisC-2; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D AFE_3042 hisC-1; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D AFE_0859 pyridine nucleotide-disulfide oxidoreductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3]
C 00380 Tryptophan metabolism
D AFE_1893 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_3068 pdhC; pyruvate dehydrogenase complex, E2 and E3 components K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_0958 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:afr00400]
D AFE_2671 phospho-2-dehydro-3-deoxyheptonate aldolase, putative K03856 AROA2; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D AFE_0899 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 AROA2; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D AFE_0733 aroB; 3-dehydroquinate synthase K13829 aroKB; shikimate kinase / 3-dehydroquinate synthase [EC:2.7.1.71 4.2.3.4]
D AFE_1802 fructose-bisphosphate aldolase, putative K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11]
D AFE_0197 aroQ; 3-dehydroquinate dehydratase, type II K03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10]
D AFE_0182 aroE; shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
D AFE_0734 aroK; shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D AFE_0901 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D AFE_1972 aroC; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D AFE_3245 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D AFE_3244 pabA; para-aminobenzoate synthase glutamine amidotransferase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D AFE_3243 trpD; anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D AFE_2070 trpF; N-(5'phosphoribosyl)anthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
D AFE_3242 trpC; indole-3-glycerol phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D AFE_2068 trpA; tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D AFE_2069 trpB; tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D AFE_0897 pheA; chorismate mutase/prephenate dehydratase K14170 pheA; chorismate mutase / prephenate dehydratase [EC:5.4.99.5 4.2.1.51]
D AFE_0900 tyrA; prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D AFE_2022 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D AFE_0898 hisC-2; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D AFE_3042 hisC-1; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D AFE_0789 dioxygenase, putative K18240 xanB2; chorismate lyase / 3-hydroxybenzoate synthase [EC:4.1.3.40 4.1.3.45]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:afr00410]
D AFE_3089 panD; aspartate 1-decarboxylase K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]
D AFE_1770 panC; pantoate--beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
C 00430 Taurine and hypotaurine metabolism
D AFE_1810 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
C 00440 Phosphonate and phosphinate metabolism [PATH:afr00440]
D AFE_2280 phnI; phosphonate metabolism protein PhnI K06164 phnI; alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI [EC:2.7.8.37]
D AFE_2278 phnG; phosphonate metabolism protein PhnG K06166 phnG; alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG [EC:2.7.8.37]
D AFE_2279 phnH; phosphonate metabolism protein phnH K06165 phnH; alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH [EC:2.7.8.37]
D AFE_2283 phnL; phosphonate ABC transporter, ATP-binding protein PhnL K05780 phnL; alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [EC:2.7.8.37]
D AFE_2284 phnM protein, putative K06162 phnM; alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase [EC:3.6.1.63]
D AFE_2281 phnJ; phosphonate metabolism protein PhnJ K06163 phnJ; alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase [EC:4.7.1.1]
D AFE_0993 metallo-beta-lactamase family protein K06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55]
C 00450 Selenocompound metabolism [PATH:afr00450]
D AFE_0239 aminotransferase, class II K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D AFE_0288 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D AFE_0375 trxB; thioredoxin-disulfide reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D AFE_2971 cysNC; sulfate adenylate transferase, large subunit/adenylylsulfate kinase K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
D AFE_3125 cysN; sulfate adenylyltransferase, large subunit K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
D AFE_2970 cysD-1; sulfate adenylyltransferase, small subunit K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D AFE_3124 cysD-2; sulfate adenylyltransferase, small subunit K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D AFE_0539 sulfate adenylyltransferase, putative/adenylylsulfate kinase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D AFE_2672 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism
D AFE_0295 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:afr00470]
D AFE_2818 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D AFE_0203 ddlB; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D AFE_2842 murI; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
D AFE_0208 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D AFE_2743 dapF; diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D AFE_3279 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
C 00480 Glutathione metabolism [PATH:afr00480]
D AFE_3064 gshA; glutamate--cysteine ligase K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2]
D AFE_3063 gshB; glutathione synthetase K01920 gshB; glutathione synthase [EC:6.3.2.3]
D AFE_2201 pepA; cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D AFE_1873 pepN; aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D AFE_2594 gst; glutathione S-transferase K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D AFE_1474 glutathione S-transferase, putative K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D AFE_0177 glutathione S-transferase family protein K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D AFE_0291 glutathione S-transferase family protein K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D AFE_0366 gor; glutathione reductase K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7]
D AFE_0424 icd; isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D AFE_2024 6-phosphogluconate dehydrogenase family protein K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D AFE_2025 zwf; glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D AFE_0367 AhpC/TSA family/glutaredoxin domain protein K24136 pgdX; glutathione-dependent peroxiredoxin [EC:1.11.1.27]
D AFE_2160 conserved hypothetical protein K00797 speE; spermidine synthase [EC:2.5.1.16]
D AFE_0150 conserved hypothetical protein K00797 speE; spermidine synthase [EC:2.5.1.16]
D AFE_0156 speE; spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis [PATH:afr00540]
D AFE_1456 lpxA; acyl-(acyl-carrier-protein)-UDP-N-acetylglucosamine acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
D AFE_0223 lpxC; UDP-3-0-acyl N-acetylglucosamine deacetylase K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]
D AFE_1454 lpxD; UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]
D AFE_1987 lpxH; UDP-2,3-diacylglucosamine hydrolase K03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]
D AFE_1459 lpxB; lipid A disaccharide synthase LpxB K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]
D AFE_0489 lpxK; tetraacyldisaccharide 4'-kinase K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]
D AFE_3030 sugar isomerase, KpsF/GutQ family K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]
D AFE_0848 kdsA; 3-deoxy-8-phosphooctulonate synthase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]
D AFE_3029 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]
D AFE_0491 kdsB; 3-deoxy-D-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]
D AFE_0237 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]
D AFE_2677 3-deoxy-D-manno-octulosonic-acid transferase domain protein K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]
D AFE_0238 lipid A biosynthesis lauroyl acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-]
D AFE_0258 hypothetical protein K12976 pagL; lipid A 3-O-deacylase [EC:3.1.1.-]
D AFE_1831 hypothetical protein K12976 pagL; lipid A 3-O-deacylase [EC:3.1.1.-]
D AFE_0714 gmhA; phosphoheptose isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
D AFE_1406 kinase, pfkB family K21344 rfaE1; D-glycero-beta-D-manno-heptose-7-phosphate kinase [EC:2.7.1.167]
D AFE_2582 histidinol-phosphate phosphatase domain protein K03273 gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83]
D AFE_1967 rfaD; ADP-L-glycero-D-mannoheptose-6-epimerase K03274 gmhD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20]
D AFE_0235 rfaC; lipopolysaccharide heptosyltransferase 1 K02841 waaC; lipopolysaccharide heptosyltransferase I [EC:2.4.99.23]
D AFE_0138 LPS heptosyltransferase II K02843 waaF; lipopolysaccharide heptosyltransferase II [EC:2.4.99.24]
D AFE_0232 O-antigen polymerase family protein K02847 waaL; O-antigen ligase [EC:2.4.99.26]
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:afr00541]
D AFE_0445 galU; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D AFE_1342 galE; UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D AFE_2322 conserved hypothetical protein K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D AFE_1343 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D AFE_1405 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D AFE_0618 UDP-glucose/GDP-mannose dehydrogenase family protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D AFE_0609 NAD-dependent epimerase/dehydratase family protein K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]
D AFE_1966 NAD-dependent epimerase/dehydratase family protein K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]
D AFE_3295 rfbA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D AFE_0441 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D AFE_3294 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D AFE_0442 rfbD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
D AFE_0252 CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3-dehydrase reductase, putative K00523 ascD; CDP-4-dehydro-6-deoxyglucose reductase, E3 [EC:1.17.1.1]
D AFE_0860 iron-sulfur cluster-binding protein/oxidoreductase, FAD/NAD-binding K00523 ascD; CDP-4-dehydro-6-deoxyglucose reductase, E3 [EC:1.17.1.1]
D AFE_1366 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
D AFE_3293 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
D AFE_2960 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
D AFE_0943 phosphomannomutase, putative K01840 manB; phosphomannomutase [EC:5.4.2.8]
D AFE_3292 gmd-2; GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]
D AFE_2977 gmd-1; GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]
D AFE_3291 NAD-dependent epimerase/dehydratase family protein K15856 rmd; GDP-4-dehydro-6-deoxy-D-mannose reductase [EC:1.1.1.281]
D AFE_1540 aminotransferase, DegT/DnrJ/EryC1/StrS family K13010 per; perosamine synthetase [EC:2.6.1.102]
D AFE_3201 glmU; UDP-N-acetylglucosamine pyrophosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
C 00550 Peptidoglycan biosynthesis [PATH:afr00550]
D AFE_3039 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D AFE_0204 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D AFE_0205 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D AFE_0208 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D AFE_0211 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D AFE_0203 ddlB; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D AFE_0210 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D AFE_0359 dgkA; diacylglycerol kinase K00887 dgkA; undecaprenol kinase [EC:2.7.1.66]
D AFE_1448 uppS; undecaprenyl diphosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D AFE_0636 undecaprenol kinase, putative K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D AFE_0209 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D AFE_0206 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D AFE_2223 penicillin-binding protein 1A, putative K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D AFE_2254 penicillin-binding protein 1C, putative K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]
D AFE_2565 mrdA; penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D AFE_2144 penicillin-binding protein 2, putative K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D AFE_2895 peptidoglycan synthetase FtsI, putative K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D AFE_0212 ftsI; peptidoglycan synthetase FtsI K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D AFE_2567 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D AFE_2350 D-alanyl-D-alanine carboxypeptidase, putative K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D AFE_2923 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D AFE_1960 dacB; D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
D AFE_2172 beta-lactamase K21469 pbp4b; serine-type D-Ala-D-Ala carboxypeptidase [EC:3.4.16.4]
C 00552 Teichoic acid biosynthesis [PATH:afr00552]
D AFE_0636 undecaprenol kinase, putative K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D AFE_1427 glycosyl transferase, group 1 family protein K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis [PATH:afr00543]
D AFE_0671 cysE-2; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D AFE_1505 cysE-1; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:afr00730]
D AFE_0948 thiC; thiamine biosynthesis protein ThiC K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D AFE_3305 phosphomethylpyrimidine kinase, putative K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]
D AFE_1537 iscS-1; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D AFE_0673 iscS-3; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D AFE_1507 iscS-2; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D AFE_1956 oxidoreductase, FAD-binding K03153 thiO; glycine oxidase [EC:1.4.3.19]
D AFE_1974 dxs; 1-deoxy-D-xylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
D AFE_0643 thiG; thiamin biosynthesis protein ThiG K03149 thiG; thiazole synthase [EC:2.8.1.10]
D AFE_3304 thiE; thiamine-phosphate pyrophosphorylase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
D AFE_0928 thiL; thiamine-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D AFE_0348 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:afr00740]
D AFE_0299 ribBA; 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
D AFE_0297 ribD; riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D AFE_1994 ribB; 3,4-dihydroxy-2-butanone 4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D AFE_0300 ribH; 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D AFE_0298 ribE; riboflavin synthase, alpha subunit K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D AFE_0557 ribF; riboflavin biosynthesis protein RibF K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]
D AFE_0647 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, putative K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00750 Vitamin B6 metabolism [PATH:afr00750]
D AFE_0628 pdxH; pyridoxamine 5'-phosphate oxidase K00275 pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5]
D AFE_0895 serC; phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
D AFE_0165 pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase K00097 pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase [EC:1.1.1.262]
D AFE_1403 pdxJ; pyridoxal phosphate biosynthetic protein PdxJ K03474 pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2]
D AFE_0474 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
C 00760 Nicotinate and nicotinamide metabolism [PATH:afr00760]
D AFE_1392 nadB; L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D AFE_0057 nadA; quinolinate synthetase complex, subunit A K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D AFE_2206 nadC; nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D AFE_0468 surE; acid phosphatase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D AFE_2948 nadD; nicotinate (nicotinamide) nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]
D AFE_0428 nadE; glutamine-dependent NAD+ synthetase K01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]
D AFE_0930 CinA family protein K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]
D AFE_0451 ppnK; ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D AFE_1546 succinate-semialdehyde dehydrogenase, putative K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00770 Pantothenate and CoA biosynthesis [PATH:afr00770]
D AFE_0745 ilvB; acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D AFE_0746 ilvN; acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D AFE_0747 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D AFE_0662 ilvD-2; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D AFE_1673 ilvD-1; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D AFE_1771 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
D AFE_1770 panC; pantoate--beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
D AFE_0452 transcriptional activator, putative, Baf family K03525 coaX; type III pantothenate kinase [EC:2.7.1.33]
D AFE_0357 coaBC; phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D AFE_2755 coaD; pantetheine-phosphate adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D AFE_0187 coaE; dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]
D AFE_1404 acpS; holo-(acyl-carrier-protein) synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
D AFE_0547 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D AFE_3089 panD; aspartate 1-decarboxylase K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]
C 00780 Biotin metabolism [PATH:afr00780]
D AFE_0245 bioC; biotin synthesis protein BioC K02169 bioC; malonyl-CoA O-methyltransferase [EC:2.1.1.197]
D AFE_0796 3-oxoacyl-(acyl-carrier-protein) synthase, putative K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]
D AFE_1910 fabF; 3-oxoacyl-(acyl-carrier-protein) synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D AFE_0793 3-oxoacyl-(acyl-carrier-protein) reductase, putative K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D AFE_1908 fabG; 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D AFE_1455 fabZ; beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D AFE_0420 fabI; enoyl-(acyl-carrier-protein) reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D AFE_0244 bioH; bioH protein K02170 bioH; pimeloyl-[acyl-carrier protein] methyl ester esterase [EC:3.1.1.85]
D AFE_0243 bioF; 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D AFE_3011 8-amino-7-oxononanoate synthase, putative K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D AFE_1924 bioA; adenosylmethionine-8-amino-7-oxononanoate aminotransferase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
D AFE_1675 bioD-1; dethiobiotin synthetase K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3]
D AFE_0246 bioD-2; dethiobiotin synthetase K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3]
D AFE_0259 bioB; biotin synthase K01012 bioB; biotin synthase [EC:2.8.1.6]
D AFE_0453 birA; birA bifunctional protein K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:afr00785]
D AFE_2569 lipB; lipoate-protein ligase B K03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181]
D AFE_2570 lipA; lipoic acid synthetase K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D AFE_2546 radical SAM domain protein K09711 lipS1; lipoyl synthase
D AFE_2543 radical SAM domain protein K24689 lipS2; lipoyl synthase
D AFE_2721 lipoate-protein ligase A, putative K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D AFE_2545 lipoate-protein ligase A, putative K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D AFE_1893 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_3068 pdhC; pyruvate dehydrogenase complex, E2 and E3 components K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_0958 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_1813 dehydrogenase complex, E1 component, alpha subunit, putative K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D AFE_3070 pdhA; pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D AFE_1812 dehydrogenase complex, E1 component, beta subunit, putative K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D AFE_3069 pdhB; pyruvate dehydrogenase, E1 component, pyruvate dehydrogenase beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D AFE_1811 2-oxo acid dehydrogenase, acyltransferase, putative K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D AFE_0981 gcvP; glycine dehydrogenase, decarboxylating K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D AFE_0982 glycine dehydrogenase (decarboxylating), subunit 2 K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D AFE_0979 gcvT; glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D AFE_2869 glycine cleavage system H protein, putative K02437 gcvH; glycine cleavage system H protein
D AFE_0980 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D AFE_2549 glycine cleavage system protein H, putative K02437 gcvH; glycine cleavage system H protein
D AFE_2547 glycine cleavage system H protein, putative K02437 gcvH; glycine cleavage system H protein
C 00790 Folate biosynthesis [PATH:afr00790]
D AFE_1973 conserved hypothetical protein TIGR00294 K09007 folE2; GTP cyclohydrolase IB [EC:3.5.4.16]
D AFE_0126 folB; dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]
D AFE_2635 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D AFE_2066 folC; folylpolyglutamate synthase/dihydrofolate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
D AFE_0299 ribBA; 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
D AFE_0576 pabB; para-aminobenzoate synthase, component I K01665 pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85]
D AFE_1911 4-amino-4-deoxychorismate lyase, putative K02619 pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38]
D AFE_1861 phhB; pterin-4-alpha-carbinolamine dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D AFE_0129 oxidoreductase, short-chain dehydrogenase/reductase family K03793 PTR1; pteridine reductase [EC:1.5.1.33]
D AFE_0069 radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D AFE_0068 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D AFE_0752 GTP cyclohydrolase I family protein K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D AFE_2559 moaA; molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D AFE_2561 moaC; molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D AFE_0976 moaE; molybdopterin converting factor, subunit 2 K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D AFE_3217 moaB; molybdenum cofactor biosynthesis protein B K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D AFE_2078 moeA; molybdopterin biosynthesis MoeA protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D AFE_2076 mobA; molybdopterin-guanine dinucleotide biosynthesis protein A K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
C 00670 One carbon pool by folate [PATH:afr00670]
D AFE_1877 folD; methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D AFE_0295 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D AFE_1896 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D AFE_2260 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D AFE_0020 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D AFE_0979 gcvT; glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D AFE_0732 thyX; thymidylate synthase, flavin-dependent K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
D AFE_0535 metF; 5,10-methylenetetrahydrofolate reductase K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]
D AFE_2140 5-formyltetrahydrofolate cyclo-ligase family protein K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:afr00860]
D AFE_0422 gltX-2; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D AFE_2761 hemA; glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D AFE_3303 hemL; glutamate-1-semialdehyde-2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D AFE_3298 hemB; delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D AFE_3300 hemC; porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D AFE_0728 hemE; uroporphyrinogen decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]
D AFE_2263 hemF; coproporphyrinogen III oxidase, aerobic K00228 CPOX; coproporphyrinogen III oxidase [EC:1.3.3.3]
D AFE_0134 hemN; oxygen-independent coproporphyrinogen III oxidase K02495 hemN; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.98.3]
D AFE_0570 hemG; protoporphyrinogen oxidase K00231 PPOX; protoporphyrinogen/coproporphyrinogen III oxidase [EC:1.3.3.4 1.3.3.15]
D AFE_0179 hemH; ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9]
D AFE_3126 cobA; uroporphyrin-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D AFE_0635 cyoE-1; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D AFE_3143 cyoE-2; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D AFE_3127 conserved hypothetical protein K03795 cbiX; sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
D AFE_1297 cobalamin biosynthesis protein, CobS family K09882 cobS; cobaltochelatase CobS [EC:6.6.1.2]
D AFE_0786 heme-utilization protein HutZ, putative K07226 hutZ; heme oxygenase (biliverdin-IX-beta and delta-forming) [EC:1.14.99.58]
D AFE_1682 bfr; bacterioferritin K03594 bfr; bacterioferritin [EC:1.16.3.1]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:afr00130]
D AFE_0593 chorismate lyase family protein K03181 ubiC; chorismate lyase [EC:4.1.3.40]
D AFE_0789 dioxygenase, putative K18240 xanB2; chorismate lyase / 3-hydroxybenzoate synthase [EC:4.1.3.40 4.1.3.45]
D AFE_0592 ubiA; 4-hydroxybenzoate polyprenyl transferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D AFE_2383 ubiD; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98]
D AFE_0647 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, putative K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D AFE_2389 ubiH-1; 2-octaprenyl-6-methoxyphenol hydroxylase K18800 ubiI; 2-polyprenylphenol 6-hydroxylase [EC:1.14.13.240]
D AFE_1825 ubiG; 3-demethylubiquinone-9 3-methyltransferase K00568 ubiG; 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase [EC:2.1.1.222 2.1.1.64]
D AFE_2388 ubiH-2; 2-octaprenyl-6-methoxyphenol hydroxylase K03185 ubiH; 2-octaprenyl-6-methoxyphenol hydroxylase [EC:1.14.13.-]
D AFE_0289 ubiE; ubiquinone/menaquinone biosynthesis methlytransferase UbiE K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]
D AFE_3239 Coq7 family protein K06134 COQ7; 3-demethoxyubiquinol 3-hydroxylase [EC:1.14.99.60]
D AFE_0460 wrbA; trp repressor binding protein K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
D AFE_3223 WrbA family protein K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:afr00900]
D AFE_1974 dxs; 1-deoxy-D-xylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
D AFE_1450 dxr; 1-deoxy-D-xylulose 5-phosphate reductoisomerase K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]
D AFE_0370 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60]
D AFE_2764 ispE; 4-diphosphocytidyl-2C-methyl-D-erythritol kinase K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]
D AFE_0371 ispF; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase K01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12]
D AFE_1933 ispG; 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]
D AFE_3258 ispH; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase K03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]
D AFE_0647 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, putative K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D AFE_1975 ispA; geranyltranstransferase K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
D AFE_2899 ispB; octaprenyl-diphosphate synthase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D AFE_1448 uppS; undecaprenyl diphosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis [PATH:afr00909]
D AFE_2124 shc; squalene-hopene cyclase K06045 shc; squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:5.4.99.17 4.2.1.129]
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis [PATH:afr00906]
D AFE_2125 phytoene/squalene synthetase family protein K10208 crtM; 4,4'-diapophytoene synthase [EC:2.5.1.96]
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D AFE_1843 tkt-1; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D AFE_3252 tkt-2; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis [PATH:afr00523]
D AFE_3295 rfbA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D AFE_0441 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D AFE_3294 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D AFE_0442 rfbD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
D AFE_3163 isochorismate pyruvate lyase, putative K04782 pchB; isochorismate pyruvate lyase [EC:4.2.99.21]
C 01055 Biosynthesis of vancomycin group antibiotics
D AFE_0441 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
D AFE_0806 penicillin amidase family protein K01434 pac; penicillin G amidase [EC:3.5.1.11]
C 00332 Carbapenem biosynthesis [PATH:afr00332]
D AFE_0281 proB-3; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D AFE_1783 proB-2; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D AFE_2464 proB-1; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D AFE_2238 amino acid kinase family protein K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D AFE_0454 proA; gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
C 00261 Monobactam biosynthesis [PATH:afr00261]
D AFE_2971 cysNC; sulfate adenylate transferase, large subunit/adenylylsulfate kinase K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
D AFE_3125 cysN; sulfate adenylyltransferase, large subunit K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
D AFE_2970 cysD-1; sulfate adenylyltransferase, small subunit K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D AFE_3124 cysD-2; sulfate adenylyltransferase, small subunit K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D AFE_0539 sulfate adenylyltransferase, putative/adenylylsulfate kinase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D AFE_0407 aspartate kinase, monofunctional class K00928 lysC; aspartate kinase [EC:2.7.2.4]
D AFE_2074 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D AFE_2358 dapA; dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D AFE_2663 dapB; dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:afr00521]
D AFE_2841 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
D AFE_2324 phosphoglucomutase, putative K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
D AFE_3254 inositol monophosphatase family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D AFE_0669 inositol monophosphate family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D AFE_3295 rfbA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D AFE_0441 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D AFE_3294 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D AFE_0442 rfbD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
D AFE_2841 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
C 00525 Acarbose and validamycin biosynthesis [PATH:afr00525]
D AFE_3295 rfbA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D AFE_0441 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
C 00401 Novobiocin biosynthesis [PATH:afr00401]
D AFE_0900 tyrA; prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D AFE_2022 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D AFE_0898 hisC-2; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D AFE_3042 hisC-1; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D AFE_3245 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D AFE_3244 pabA; para-aminobenzoate synthase glutamine amidotransferase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D AFE_1907 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D AFE_0793 3-oxoacyl-(acyl-carrier-protein) reductase, putative K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D AFE_1908 fabG; 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D AFE_0420 fabI; enoyl-(acyl-carrier-protein) reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
D AFE_0797 acyl carrier protein, putative K02078 acpP; acyl carrier protein
D AFE_1909 acpP; acyl carrier protein K02078 acpP; acyl carrier protein
C 00999 Biosynthesis of various plant secondary metabolites [PATH:afr00999]
D AFE_0532 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D AFE_0182 aroE; shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation
C 00627 Aminobenzoate degradation [PATH:afr00627]
D AFE_2776 benzoylformate decarboxylase K01576 mdlC; benzoylformate decarboxylase [EC:4.1.1.7]
D AFE_0647 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, putative K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00364 Fluorobenzoate degradation [PATH:afr00364]
D AFE_2210 carboxymethylenebutenolidase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45]
C 00625 Chloroalkane and chloroalkene degradation [PATH:afr00625]
D AFE_2088 zinc-binding alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D AFE_0697 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D AFE_1520 nifK; nitrogenase molybdenum-iron protein, beta subunit K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]
D AFE_1522 nifH; nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH
D AFE_1521 nifD; nitrogenase molybdenum-iron protein, alpha subunit K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1]
D AFE_1981 PQQ enzyme repeat protein K00114 exaA; alcohol dehydrogenase (cytochrome c) [EC:1.1.2.8]
C 00361 Chlorocyclohexane and chlorobenzene degradation [PATH:afr00361]
D AFE_2210 carboxymethylenebutenolidase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45]
C 00623 Toluene degradation [PATH:afr00623]
D AFE_2210 carboxymethylenebutenolidase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45]
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation
D AFE_3286 hynL; [Ni/Fe] hydrogenase, large subunit K06281 hyaB; hydrogenase large subunit [EC:1.12.99.6]
D AFE_3283 hynS; [Ni/Fe] hydrogenase, small subunit K06282 hyaA; hydrogenase small subunit [EC:1.12.99.6]
D AFE_0702 hybC; hydrogenase-2, large subunit K23549 hupV; uptake hydrogenase large subunit [EC:1.12.99.6]
D AFE_0701 hybA; hydrogenase-2, small subunit K23548 hupU; uptake hydrogenase small subunit [EC:1.12.99.6]
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation [PATH:afr00791]
D AFE_0779 cyanuric acid amidohydrolase K03383 atzD; cyanuric acid amidohydrolase [EC:3.5.2.15]
D AFE_0782 amidohydrolase, AtzE family K19837 atzE; 1-carboxybiuret hydrolase [EC:3.5.1.131]
C 00930 Caprolactam degradation
D AFE_2005 isonitrile hydratase, putative K18199 inhA; cyclohexyl-isocyanide hydratase [EC:4.2.1.103]
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation [PATH:afr00626]
D AFE_2088 zinc-binding alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D AFE_0697 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:afr03020]
D AFE_0320 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D AFE_0321 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D AFE_0354 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D AFE_0564 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
C 03022 Basal transcription factors
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:afr03010]
D AFE_0903 rpsA; ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D AFE_1444 rpsB; ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D AFE_0333 rpsC; ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D AFE_0353 rpsD; ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D AFE_0344 rpsE; ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D AFE_2824 rpsF; ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D AFE_0323 rpsG; ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D AFE_0341 rpsH; ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D AFE_3074 rpsI; ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D AFE_0326 rpsJ; ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D AFE_0352 rpsK; ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D AFE_0322 rpsL; ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D AFE_0351 rpsM; ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D AFE_0340 rpsN; ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D AFE_0394 rpsO; ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D AFE_2855 rpsP; ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D AFE_0336 rpS17; ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D AFE_2823 rpS18; ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D AFE_0331 rpsS; ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D AFE_2188 rpsT; ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D AFE_2340 rpsU; ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D AFE_0316 rplA; ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D AFE_0330 rplB; ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D AFE_0327 rplC; ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D AFE_0328 rplD; ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D AFE_0339 rplE; ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D AFE_0342 rplF; ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D AFE_0318 rplL; ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D AFE_2820 rplI; ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D AFE_0317 rplJ; ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D AFE_0315 rplK; ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D AFE_3075 rplM; ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D AFE_0337 rplN; ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D AFE_0346 rplO; ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D AFE_0334 rplP; ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D AFE_0355 rplQ; ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D AFE_0343 rplR; ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D AFE_2852 rplS; ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D AFE_2611 rplT; ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D AFE_0285 rplU; ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D AFE_0332 rplV; ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D AFE_0329 rplW; ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D AFE_0338 rplX; ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D AFE_2145 rplY; ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D AFE_0284 rpmA; ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D AFE_2670 rpmB; ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D AFE_0335 rpmC; ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D AFE_0345 rpmD; ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D AFE_0659 rpmE; ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D AFE_1904 rpmF; ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D AFE_2669 rpmG; ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D AFE_0035 rpmH; ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D AFE_2612 rpmI; ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D AFE_0350 rpmJ; ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D AFE_0384 rrsB; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D AFE_3084 rrsA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D AFE_0387 rrlB; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D AFE_3081 rrlA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D AFE_0388 rrfB; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D AFE_3080 rrfA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:afr00970]
D AFE_0994 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D AFE_1191 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D AFE_0386 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D AFE_3082 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D AFE_2353 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D AFE_0844 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D AFE_1156 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D AFE_1155 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D AFE_0586 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D AFE_2735 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D AFE_2016 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D AFE_1165 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D AFE_1829 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D AFE_1190 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D AFE_1179 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D AFE_0916 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D AFE_1172 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D AFE_0856 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D AFE_1161 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D AFE_2742 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D AFE_2765 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D AFE_1173 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D AFE_2359 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D AFE_2128 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D AFE_1163 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D AFE_1164 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D AFE_0309 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D AFE_1192 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D AFE_0855 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D AFE_2370 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D AFE_2767 tRNA-His K14226 tRNA-His; tRNA His
D AFE_1180 tRNA-His K14226 tRNA-His; tRNA His
D AFE_0385 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D AFE_3083 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D AFE_1166 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D AFE_1159 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_2315 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_1162 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_1157 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_1946 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_1890 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_2213 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_1187 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_2631 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_1160 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D AFE_1954 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D AFE_1182 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D AFE_0084 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D AFE_2335 tRNA-Met K14230 tRNA-Met; tRNA Met
D AFE_1171 tRNA-Met K14230 tRNA-Met; tRNA Met
D AFE_3233 tRNA-Met K14230 tRNA-Met; tRNA Met
D AFE_0383 tRNA-Met K14230 tRNA-Met; tRNA Met
D AFE_1168 tRNA-Met K14230 tRNA-Met; tRNA Met
D AFE_0145 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D AFE_1158 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D AFE_2326 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D AFE_2606 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D AFE_2898 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D AFE_1183 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D AFE_1189 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D AFE_0656 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D AFE_1185 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D AFE_2055 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D AFE_1181 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D AFE_1186 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D AFE_1188 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D AFE_1916 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D AFE_1193 pseudogene K14233 tRNA-Ser; tRNA Ser
D AFE_1177 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D AFE_0310 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D AFE_0891 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D AFE_1175 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D AFE_0578 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D AFE_0312 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D AFE_1194 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D AFE_0308 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D AFE_1184 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D AFE_0915 tRNA-Val K14237 tRNA-Val; tRNA Val
D AFE_2615 tRNA-Val K14237 tRNA-Val; tRNA Val
D AFE_1555 tRNA-Val K14237 tRNA-Val; tRNA Val
D AFE_1167 tRNA-Val K14237 tRNA-Val; tRNA Val
D AFE_0422 gltX-2; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D AFE_2222 gltX-1; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
D AFE_2111 gatA; glutamyl-tRNA(Gln)/aspartyl-tRNA(Asn) amidotransferase, A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D AFE_2110 gatB; glutamyl-tRNA(Gln)/aspartyl-tRNA(Asn) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D AFE_2112 gatC; glutamyl-tRNA(Gln)/aspartyl-tRNA(Asn) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D AFE_0934 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D AFE_0056 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D AFE_2580 glyQ; glycyl-tRNA synthetase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D AFE_2581 glyS; glycyl-tRNA synthetase, beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D AFE_2614 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D AFE_0380 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D AFE_2221 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D AFE_2672 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D AFE_0020 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D AFE_2204 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D AFE_0459 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D AFE_0556 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D AFE_0480 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D AFE_0170 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D AFE_2132 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D AFE_1934 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D AFE_2610 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D AFE_2609 pheT; phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D AFE_3085 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D AFE_1789 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:afr03060]
D AFE_0347 secY; preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D AFE_0313 secE; preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE
D AFE_2632 secG; preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG
D AFE_2057 secD; protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD
D AFE_2056 secF; protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D AFE_2058 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D AFE_0032 inner membrane protein, 60 kDa K03217 yidC; YidC/Oxa1 family membrane protein insertase
D AFE_0225 secA; preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D AFE_2127 secB; preprotein translocase, SecB subunit K03071 secB; preprotein translocase subunit SecB
D AFE_2856 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D AFE_1918 sRNA K01983 ffs; SRP RNA
D AFE_1917 srpB; Bacterial signal recognition particle RNA K01983 ffs; SRP RNA
D AFE_2753 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D AFE_3131 twin-arginine translocation protein, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D AFE_3048 tatA; twin-arginine translocation protein, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D AFE_3049 tatB; twin-arginine translocation protein TatB K03117 tatB; sec-independent protein translocase protein TatB
D AFE_3050 tatC; Sec-independent protein translocase TatC K03118 tatC; sec-independent protein translocase protein TatC
D AFE_1398 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D AFE_0555 lspA; signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:afr04122]
D AFE_1537 iscS-1; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D AFE_0673 iscS-3; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D AFE_1507 iscS-2; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D AFE_2557 conserved hypothetical protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D AFE_0680 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D AFE_0976 moaE; molybdopterin converting factor, subunit 2 K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D AFE_2559 moaA; molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D AFE_0975 moaD; molybdopterin converting factor, subunit 1 K03636 moaD; sulfur-carrier protein
D AFE_0652 moeB; molybdopterin biosynthesis MoeB protein K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80]
D AFE_2561 moaC; molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D AFE_3217 moaB; molybdenum cofactor biosynthesis protein B K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D AFE_0642 thiS; thiamine biosynthesis protein ThiS K03154 thiS; sulfur carrier protein
C 03050 Proteasome
C 03018 RNA degradation [PATH:afr03018]
D AFE_2173 NUDIX hydrolase K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]
D AFE_2220 ribonuclease, Rne/Rng family K08300 rne; ribonuclease E [EC:3.1.26.12]
D AFE_0849 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D AFE_0395 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D AFE_1433 rhlE; ATP-dependent RNA helicase RhlE K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]
D AFE_1891 vacB; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D AFE_0589 ATP-dependent RNA helicase, DEAD/DEAH box family K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D AFE_2194 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D AFE_0658 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D AFE_2665 dnaK; chaperone protein Dnak K04043 dnaK; molecular chaperone DnaK
D AFE_0542 groEL; chaperonin, 60 kDa K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D AFE_1884 hfq; RNA chaperone Hfq K03666 hfq; host factor-I protein
D AFE_1876 ppk; polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
D AFE_1892 conserved hypothetical protein K22468 ppk2; polyphosphate kinase [EC:2.7.4.34]
D AFE_1775 pcnB; polyA polymerase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:afr03030]
D AFE_0400 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D AFE_1461 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D AFE_1919 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D AFE_1914 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D AFE_0457 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D AFE_2203 holC; DNA polymerase III, chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
D AFE_0001 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D AFE_2819 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D AFE_2337 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D AFE_1569 ssb-2; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_2845 ssb-1; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_1260 ssb-3; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_0399 rnhA-2; ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D AFE_1199 rnhA-1; ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D AFE_1460 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D AFE_3094 polI; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D AFE_0757 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D AFE_1230 DNA ligase, NAD-dependent, putative K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03410 Base excision repair [PATH:afr03410]
D AFE_2682 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AFE_3015 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D AFE_2758 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D AFE_0463 formamidopyrimidine-DNA glycosylase, putative K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D AFE_1848 base excision repair protein, HhH-GPD family K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D AFE_2799 transcriptional regulator, Ada family/DNA-3-methyladenine glycosylase II K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D AFE_1217 uracil-DNA glycosylase, family 4 K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D AFE_2882 uracil-DNA glycosylase family 4 protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D AFE_0174 xth-2; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D AFE_0178 xth-1; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D AFE_3094 polI; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D AFE_0476 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D AFE_0757 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D AFE_1230 DNA ligase, NAD-dependent, putative K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03420 Nucleotide excision repair [PATH:afr03420]
D AFE_0369 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D AFE_2847 uvrA; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
D AFE_0845 uvrB; excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
D AFE_0853 uvrC; excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C
D AFE_3101 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D AFE_1137 ATP-dependent DNA helicase, UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D AFE_3094 polI; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D AFE_0757 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D AFE_1230 DNA ligase, NAD-dependent, putative K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03430 Mismatch repair [PATH:afr03430]
D AFE_1760 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D AFE_2338 MutS2 family protein K07456 mutS2; DNA mismatch repair protein MutS2
D AFE_0744 MutS domain V protein K07456 mutS2; DNA mismatch repair protein MutS2
D AFE_1927 mutL; mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D AFE_3101 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D AFE_1137 ATP-dependent DNA helicase, UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D AFE_1980 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D AFE_1976 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D AFE_1767 exodeoxyribonuclease X, putative K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D AFE_0476 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D AFE_1569 ssb-2; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_2845 ssb-1; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_1260 ssb-3; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_1461 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D AFE_0001 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D AFE_1919 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D AFE_0457 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D AFE_1914 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D AFE_0400 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D AFE_2203 holC; DNA polymerase III, chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
D AFE_0757 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D AFE_1230 DNA ligase, NAD-dependent, putative K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D AFE_1568 methyltransferase, putative K06223 dam; DNA adenine methylase [EC:2.1.1.72]
C 03440 Homologous recombination [PATH:afr03440]
D AFE_0476 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D AFE_1569 ssb-2; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_2845 ssb-1; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_1260 ssb-3; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_0002 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
D AFE_1402 DNA repair protein RecO, putative K03584 recO; DNA repair protein RecO (recombination protein O)
D AFE_1921 recR; recombination protein RecR K06187 recR; recombination protein RecR
D AFE_0932 recA; recA protein K03553 recA; recombination protein RecA
D AFE_3094 polI; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D AFE_0061 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D AFE_0062 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AFE_0060 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AFE_0568 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D AFE_3194 ATP-dependent DNA helicase RecG domain protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D AFE_0827 ATP-dependent DNA helicase, putative K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D AFE_2932 recB; exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
D AFE_2931 recC; exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
D AFE_2933 recD; exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
D AFE_1047 helicase, RecD/TraA family K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
D AFE_1461 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D AFE_0001 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D AFE_1919 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D AFE_0457 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D AFE_1914 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D AFE_0400 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D AFE_2203 holC; DNA polymerase III, chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
D AFE_0591 priA; primosomal protein N` K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
C 03450 Non-homologous end-joining
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus and Lyssavirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:afr02010]
D AFE_1498 ABC transporter, periplasmic substrate-binding protein, putative K15495 wtpA; molybdate/tungstate transport system substrate-binding protein
D AFE_2190 ABC transporter, permease protein K15496 wtpB; molybdate/tungstate transport system permease protein
D AFE_2189 ABC transporter, ATP-binding protein K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6]
D AFE_1493 molybdenum ABC transporter, periplasmic molybdate-binding protein, putative K02020 modA; molybdate transport system substrate-binding protein
D AFE_1830 toluene tolerance protein, putative K07323 mlaC; phospholipid transport system substrate-binding protein
D AFE_0161 toluene tolerance protein, putative K07323 mlaC; phospholipid transport system substrate-binding protein
D AFE_2114 conserved hypothetical protein K07323 mlaC; phospholipid transport system substrate-binding protein
D AFE_2135 mce-related protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D AFE_0160 mce-related protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D AFE_0648 ABC transporter, permease protein, putative K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D AFE_0159 toluene tolerance protein Ttg2B, putative K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D AFE_0162 conserved hypothetical protein K07122 mlaB; phospholipid transport system transporter-binding protein
D AFE_0646 ABC transporter, ATP-binding protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D AFE_0158 toluene ABC transporter, ATP-binding protein, putative K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D AFE_1436 pstS-2; phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D AFE_1939 pstS-1; phosphate ABC transporter, periplasmic phosphate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein
D AFE_1940 pstC_2; phosphate ABC transporter, permease protein PstC K02037 pstC; phosphate transport system permease protein
D AFE_1437 pstC-2; phosphate ABC transporter, permease protein PstC K02037 pstC; phosphate transport system permease protein
D AFE_1941 pstC_1; phosphate ABC transporter, permease protein, putative K02038 pstA; phosphate transport system permease protein
D AFE_1438 pstA; phosphate ABC transporter, permease protein PstA K02038 pstA; phosphate transport system permease protein
D AFE_1439 pstB; phosphate ABC transporter, ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D AFE_2961 capsule polysaccharide export inner-membrane protein K10107 kpsE; capsular polysaccharide transport system permease protein
D AFE_2962 ctrC; capsule polysaccharide exporter, inner-membrane protein CtrC K09688 kpsM; capsular polysaccharide transport system permease protein
D AFE_2963 ctrD; capsule polysaccharide exporter, ATP-binding protein K09689 kpsT; capsular polysaccharide transport system ATP-binding protein [EC:7.6.2.12]
D AFE_3235 ABC-2 type transporter, permease protein, NodJ family K09694 nodJ; lipooligosaccharide transport system permease protein
D AFE_3236 ABC transporter, ATP-binding protein, NodI family K09695 nodI; lipooligosaccharide transport system ATP-binding protein
D AFE_0481 lolC; lipoprotein releasing system transmembrane protein LolC K09808 lolC_E; lipoprotein-releasing system permease protein
D AFE_0483 lolD; lipoprotein releasing system, ATP-binding protein LolD K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D AFE_2200 YjgP/YjgQ family protein K07091 lptF; lipopolysaccharide export system permease protein
D AFE_2199 YjgP/YjgQ family protein K11720 lptG; lipopolysaccharide export system permease protein
D AFE_3026 ABC transporter, ATP-binding protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]
D AFE_2751 cell division protein FtsX, putative K09811 ftsX; cell division transport system permease protein
D AFE_2752 ftsE; cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein
D AFE_0983 ABC transporter, ATP-binding protein, MsbA family K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]
D AFE_2693 type I secretion system ATPase K11004 hlyB; ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
D AFE_2167 toxin secretion ABC transporter, ATP-binding protein, HlyB family K13409 cvaB; ATP-binding cassette, subfamily B, bacterial CvaB/MchF/RaxB
D AFE_2985 ABC transporter, permease/ATP-binding protein K18893 vcaM; ATP-binding cassette, subfamily B, multidrug efflux pump
D AFE_1390 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC K16012 cydC; ATP-binding cassette, subfamily C, bacterial CydC
D AFE_1388 cydD; ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD K16013 cydD; ATP-binding cassette, subfamily C, bacterial CydD
D AFE_0552 ABC transporter, permease/ATP-binding protein K02471 bacA; vitamin B12/bleomycin/antimicrobial peptide transport system ATP-binding/permease protein
C 02060 Phosphotransferase system (PTS) [PATH:afr02060]
D AFE_3018 ptsI; phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D AFE_3019 ptsH; phosphocarrier protein HPr K02784 ptsH; phosphocarrier protein HPr
D AFE_3020 PTS system, IIA component, putative K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D AFE_3023 phosphoenolpyruvate-dependent sugar PTS system, EIIA component K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]
C 03070 Bacterial secretion system [PATH:afr03070]
D AFE_0575 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein
D AFE_2045 outer membrane efflux protein K12340 tolC; outer membrane protein
D AFE_3265 outer membrane efflux protein K12340 tolC; outer membrane protein
D AFE_2169 outer membrane toxin secretion efflux protein, putative K12340 tolC; outer membrane protein
D AFE_2692 type I secretion membrane fusion protein, HlyD family K11003 hlyD; membrane fusion protein, hemolysin D
D AFE_2693 type I secretion system ATPase K11004 hlyB; ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
D AFE_2057 secD; protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD
D AFE_2056 secF; protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D AFE_0313 secE; preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE
D AFE_2632 secG; preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG
D AFE_0347 secY; preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D AFE_2058 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D AFE_0032 inner membrane protein, 60 kDa K03217 yidC; YidC/Oxa1 family membrane protein insertase
D AFE_0225 secA; preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D AFE_2753 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D AFE_2127 secB; preprotein translocase, SecB subunit K03071 secB; preprotein translocase subunit SecB
D AFE_2856 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D AFE_3131 twin-arginine translocation protein, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D AFE_3048 tatA; twin-arginine translocation protein, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D AFE_3049 tatB; twin-arginine translocation protein TatB K03117 tatB; sec-independent protein translocase protein TatB
D AFE_3050 tatC; Sec-independent protein translocase TatC K03118 tatC; sec-independent protein translocase protein TatC
D AFE_1698 conjugal transfer -like protein K03194 virB1; type IV secretion system protein VirB1
D AFE_1699 TraG/TraD family protein K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8]
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:afr02020]
D AFE_1435 phoR; phosphate regulon sensor protein PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
D AFE_2934 transcriptional regulator, putative K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
D AFE_1434 phoB; DNA-binding response regulator PhoB K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
D AFE_2306 DNA-binding response regulator K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
D AFE_2271 transcriptional regulator, putative K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
D AFE_1436 pstS-2; phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D AFE_1939 pstS-1; phosphate ABC transporter, periplasmic phosphate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein
D AFE_3275 osmolarity sensor protein EnvZ, putative K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
D AFE_0106 sensor histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
D AFE_2318 sensor histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
D AFE_0107 DNA-binding response regulator K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
D AFE_3274 transcriptional regulator OmpR, putative K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
D AFE_2319 DNA-binding response regulator K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
D AFE_1646 serine protease, DO/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107]
D AFE_1396 serine protease, DO/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107]
D AFE_3264 efflux transporter, RND family, MFP subunit K07799 mdtA; membrane fusion protein, multidrug efflux system
D AFE_2428 heavy metal efflux system protein, putative K07810 cusF; Cu(I)/Ag(I) efflux system periplasmic protein CusF
D AFE_2782 cation efflux system protein, putative K07810 cusF; Cu(I)/Ag(I) efflux system periplasmic protein CusF
D AFE_1948 heavy metal efflux transporter, MFP subunit, putative K07798 cusB; membrane fusion protein, copper/silver efflux system
D AFE_2433 efflux transporter, RND family, MFP subunit K07798 cusB; membrane fusion protein, copper/silver efflux system
D AFE_2431 heavy metal efflux pump, CzcA family K07787 cusA; copper/silver efflux system protein
D AFE_1947 heavy metal efflux pump, CzcA family K07787 cusA; copper/silver efflux system protein
D AFE_2229 kdpD; sensor histidine kinase KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
D AFE_2228 kdpE; DNA-binding response regulator KdpE K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
D AFE_2232 kdpA-3; K+-transporting ATPase, A subunit K01546 kdpA; potassium-transporting ATPase potassium-binding subunit
D AFE_2475 kdpA-2; K+-transporting ATPase, A subunit K01546 kdpA; potassium-transporting ATPase potassium-binding subunit
D AFE_2477 kdpA-1; K+-transporting ATPase, A subunit K01546 kdpA; potassium-transporting ATPase potassium-binding subunit
D AFE_2233 kdpB-2; K+-transporting ATPase, B subunit K01547 kdpB; potassium-transporting ATPase ATP-binding subunit [EC:7.2.2.6]
D AFE_2474 kdpB-1; K+-transporting ATPase, B subunit K01547 kdpB; potassium-transporting ATPase ATP-binding subunit [EC:7.2.2.6]
D AFE_2234 kdpC-2; K+-transporting ATPase, C subunit K01548 kdpC; potassium-transporting ATPase KdpC subunit
D AFE_2473 kdpC-1; K+-transporting ATPase, C subunit K01548 kdpC; potassium-transporting ATPase KdpC subunit
D AFE_3309 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D AFE_0462 d-alanyl-d-alanine dipeptidase, putative K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
D AFE_1964 fatty acid desaturase K10255 FAD6; acyl-lipid omega-6 desaturase (Delta-12 desaturase) [EC:1.14.19.23 1.14.19.45]
D AFE_0005 spore coat protein K27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1/2/3/6
D AFE_0008 spore coat protein K27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1/2/3/6
D AFE_0006 pilus chaperone protein, putative K07346 fimC; fimbrial chaperone protein
D AFE_0007 outer membrane usher protein, putative K07347 fimD; outer membrane usher protein
D AFE_2710 pilin, putative K02651 flp; pilus assembly protein Flp/PilA
D AFE_2705 conserved hypothetical protein K02279 cpaB; pilus assembly protein CpaB
D AFE_2704 bacterial type II/III secretion system protein K02280 cpaC; pilus assembly protein CpaC
D AFE_2703 pilus assembly protein CpaE, putative K02282 cpaE; pilus assembly protein CpaE
D AFE_2702 tadA; tight adherence protein TadA K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D AFE_2701 tadB; tight adherence protein TadB, putative K12510 tadB; tight adherence protein B
D AFE_2700 tadC; tight adherence protein TadC K12511 tadC; tight adherence protein C
D AFE_2699 lipoprotein, putative K27079 tadD; tight adherence protein D
D AFE_2697 conserved hypothetical protein K27080 tadG; tight adherence protein G
D AFE_0924 glnD; protein-P-II uridylyltransferase K00990 glnD; [protein-PII] uridylyltransferase [EC:2.7.7.59]
D AFE_0429 glnB-2; nitrogen regulatory protein P-II 1 K04751 glnB; nitrogen regulatory protein P-II 1
D AFE_2462 glnB-1; nitrogen regulatory protein P-II 1 K04751 glnB; nitrogen regulatory protein P-II 1
D AFE_2902 ntrB; nitrogen regulation protein NR(II) K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
D AFE_2901 ntrC; nitrogen regulation protein NR(I) K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
D AFE_0466 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D AFE_0023 ntrY; nitrogen regulation protein NtrY, putative K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
D AFE_0024 ntrX; nitrogen assimilation regulatory protein NtrX, putative K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
D AFE_1527 nifA; Nif-specific regulatory protein K02584 nifA; Nif-specific regulatory protein
D AFE_0026 sensor histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
D AFE_0027 sigma-54 dependent transcriptional regulator/response regulator K07714 atoC; two-component system, NtrC family, response regulator AtoC
D AFE_0184 sensor protein PilS, putative K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
D AFE_0185 type IV fimbriae expression regulatory protein PilR, putative K02667 pilR; two-component system, NtrC family, response regulator PilR
D AFE_3025 rpoN; RNA polymerase sigma-54 factor K03092 rpoN; RNA polymerase sigma-54 factor
D AFE_0416 pilin, putative K02650 pilA; type IV pilus assembly protein PilA
D AFE_2957 sensor histidine kinase K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
D AFE_0449 sensor histidine kinase K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
D AFE_2955 sigma-54 dependent DNA-binding response regulator, putative K07715 glrR; two-component system, NtrC family, response regulator GlrR
D AFE_0447 sigma-54 dependent DNA-binding response regulator K07715 glrR; two-component system, NtrC family, response regulator GlrR
D AFE_0701 hybA; hydrogenase-2, small subunit K23548 hupU; uptake hydrogenase small subunit [EC:1.12.99.6]
D AFE_0702 hybC; hydrogenase-2, large subunit K23549 hupV; uptake hydrogenase large subunit [EC:1.12.99.6]
D AFE_0700 hupR; hydrogenase sigma-54 dependent DNA-binding response regulator K19641 hupR; two-component system, NtrC family, response regulator HupR/HoxA
D AFE_3283 hynS; [Ni/Fe] hydrogenase, small subunit K06282 hyaA; hydrogenase small subunit [EC:1.12.99.6]
D AFE_3286 hynL; [Ni/Fe] hydrogenase, large subunit K06281 hyaB; hydrogenase large subunit [EC:1.12.99.6]
D AFE_2429 [Ni/Fe] hydrogenase, b-type cytochrome subunit, putative K03620 hyaC; Ni/Fe-hydrogenase 1 B-type cytochrome subunit
D AFE_2344 cyclic nucleotide-binding domain protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D AFE_3136 sensor histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
D AFE_3137 DNA-binding response regulator K15012 regA; two-component system, response regulator RegA
D AFE_2729 petA-2; ubiquinol--cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D AFE_3109 petA-1; ubiquinol--cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D AFE_2730 petB-2; ubiquinol--cytochrome c reductase, cytochrome b subunit K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D AFE_3110 petB-1; ubiquinol--cytochrome c reductase, cytochrome b subunit K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D AFE_3111 petC-1; ubiquinol--cytochrome c reductase, cytochrome c1 subunit K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
D AFE_2731 petC-2; ubiquinol--cytochrome c reductase, cytochrome c1 subunit K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
D AFE_1962 cytochrome c family protein K08738 CYC; cytochrome c
D AFE_2450 cytochrome c family protein K08738 CYC; cytochrome c
D AFE_0955 cydA; cytochrome d ubiquinol oxidase, subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D AFE_0954 cydB; cytochrome d ubiquinol oxidase, subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D AFE_0575 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein
D AFE_2045 outer membrane efflux protein K12340 tolC; outer membrane protein
D AFE_3265 outer membrane efflux protein K12340 tolC; outer membrane protein
D AFE_2169 outer membrane toxin secretion efflux protein, putative K12340 tolC; outer membrane protein
D AFE_1339 polysaccharide biosynthesis/export domain protein K01991 wza; polysaccharide biosynthesis/export protein
D AFE_2975 capsule polysaccharide export protein, BexD/CtrA/VexA family K01991 wza; polysaccharide biosynthesis/export protein
D AFE_1340 tyrosine-protein kinase, putative K16692 etk-wzc; tyrosine-protein kinase Etk/Wzc [EC:2.7.10.3]
D AFE_1999 autoinducer synthesis protein K13061 rhlI; acyl homoserine lactone synthase [EC:2.3.1.184]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
D AFE_2729 petA-2; ubiquinol--cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D AFE_3109 petA-1; ubiquinol--cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:afr02024]
D AFE_1884 hfq; RNA chaperone Hfq K03666 hfq; host factor-I protein
D AFE_3245 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D AFE_3244 pabA; para-aminobenzoate synthase glutamine amidotransferase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D AFE_1999 autoinducer synthesis protein K13061 rhlI; acyl homoserine lactone synthase [EC:2.3.1.184]
D AFE_2957 sensor histidine kinase K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
D AFE_0449 sensor histidine kinase K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
D AFE_2955 sigma-54 dependent DNA-binding response regulator, putative K07715 glrR; two-component system, NtrC family, response regulator GlrR
D AFE_0447 sigma-54 dependent DNA-binding response regulator K07715 glrR; two-component system, NtrC family, response regulator GlrR
D AFE_2228 kdpE; DNA-binding response regulator KdpE K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
D AFE_1634 trbB; P-type conjugative transfer protein TrbB K20527 trbB; type IV secretion system protein TrbB [EC:7.4.2.8]
D AFE_1637 conjugal transfer protein TrbD, putative K20529 trbD; type IV secretion system protein TrbD
D AFE_1638 conjugal transfer protein trbE, putative K20530 trbE; type IV secretion system protein TrbE [EC:7.4.2.8]
D AFE_1640 conjugal transfer protein trbJ, putative K20266 trbJ; type IV secretion system protein TrbJ
D AFE_1642 conjugal transfer protein trbL, putative K07344 trbL; type IV secretion system protein TrbL
D AFE_1694 conjugal transfer protein K20531 trbF; type IV secretion system protein TrbF
D AFE_1696 conjugal transfer protein, putative K20532 trbG; type IV secretion system protein TrbG
D AFE_1695 conjugal transfer protein K20532 trbG; type IV secretion system protein TrbG
D AFE_0220 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D AFE_2344 cyclic nucleotide-binding domain protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D AFE_0297 ribD; riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D AFE_2690 type I secretion outer membrane protein, putative K18139 oprM; outer membrane protein, multidrug efflux system
D AFE_2987 peptide ABC transporter, periplasmic peptide-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D AFE_2992 peptide ABC transporter, periplasmic peptide-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D AFE_2991 peptide ABC transporter, permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein
D AFE_2990 peptide ABC transporter, permease protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D AFE_2989 peptide ABC transporter, ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D AFE_0032 inner membrane protein, 60 kDa K03217 yidC; YidC/Oxa1 family membrane protein insertase
D AFE_0313 secE; preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE
D AFE_2632 secG; preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG
D AFE_0347 secY; preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D AFE_2058 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D AFE_0225 secA; preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D AFE_2753 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D AFE_2127 secB; preprotein translocase, SecB subunit K03071 secB; preprotein translocase subunit SecB
D AFE_2856 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly [PATH:afr02040]
D AFE_2336 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor
D AFE_3025 rpoN; RNA polymerase sigma-54 factor K03092 rpoN; RNA polymerase sigma-54 factor
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D AFE_0849 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance [PATH:afr01501]
D AFE_1961 AmpG permease protein, putative K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG
D AFE_2825 nagZ; beta-hexosaminidase K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]
D AFE_0109 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system
D AFE_1879 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system
D AFE_1878 transporter, AcrB/AcrD/AcrF family K18138 acrB; multidrug efflux pump
D AFE_2690 type I secretion outer membrane protein, putative K18139 oprM; outer membrane protein, multidrug efflux system
D AFE_0575 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein
D AFE_2045 outer membrane efflux protein K12340 tolC; outer membrane protein
D AFE_3265 outer membrane efflux protein K12340 tolC; outer membrane protein
D AFE_2169 outer membrane toxin secretion efflux protein, putative K12340 tolC; outer membrane protein
D AFE_2223 penicillin-binding protein 1A, putative K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D AFE_2565 mrdA; penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D AFE_2144 penicillin-binding protein 2, putative K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D AFE_2895 peptidoglycan synthetase FtsI, putative K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D AFE_0212 ftsI; peptidoglycan synthetase FtsI K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
C 01502 Vancomycin resistance [PATH:afr01502]
D AFE_0462 d-alanyl-d-alanine dipeptidase, putative K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
D AFE_0203 ddlB; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D AFE_2818 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D AFE_0210 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D AFE_0209 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D AFE_0206 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:afr01503]
D AFE_2361 N-acetylmuramoyl-L-alanine amidase, putative K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D AFE_1646 serine protease, DO/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107]
D AFE_1396 serine protease, DO/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107]
D AFE_1088 thiol:disulfide interchange protein, DsbA family K03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15]
D AFE_0109 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system
D AFE_1879 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system
D AFE_1878 transporter, AcrB/AcrD/AcrF family K18138 acrB; multidrug efflux pump
D AFE_0575 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein
D AFE_2045 outer membrane efflux protein K12340 tolC; outer membrane protein
D AFE_3265 outer membrane efflux protein K12340 tolC; outer membrane protein
D AFE_2169 outer membrane toxin secretion efflux protein, putative K12340 tolC; outer membrane protein
D AFE_1456 lpxA; acyl-(acyl-carrier-protein)-UDP-N-acetylglucosamine acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:afr01000]
C 01001 Protein kinases [BR:afr01001]
D AFE_1340 tyrosine-protein kinase, putative K16692 etk-wzc; tyrosine-protein kinase Etk/Wzc [EC:2.7.10.3]
D AFE_1435 phoR; phosphate regulon sensor protein PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
D AFE_3275 osmolarity sensor protein EnvZ, putative K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
D AFE_0106 sensor histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
D AFE_2318 sensor histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
D AFE_2229 kdpD; sensor histidine kinase KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
D AFE_2031 sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D AFE_2902 ntrB; nitrogen regulation protein NR(II) K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
D AFE_0023 ntrY; nitrogen regulation protein NtrY, putative K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
D AFE_0026 sensor histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
D AFE_0184 sensor protein PilS, putative K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
D AFE_2957 sensor histidine kinase K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
D AFE_0449 sensor histidine kinase K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
D AFE_3136 sensor histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:afr01009]
D AFE_0534 ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D AFE_3158 htpG; heat shock protein HtpG K04079 HSP90A; molecular chaperone HtpG
D AFE_0368 serB; phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 01002 Peptidases and inhibitors [BR:afr01002]
D AFE_0555 lspA; signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36]
D AFE_0186 pilD; type IV pilus prepilin peptidase PilD K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
D AFE_2708 membrane protein, putative K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
D AFE_3281 hynD; hydrogenase maturation protease K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
D AFE_0705 hydrogenase maturation protease K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
D AFE_0936 hoxW; hydrogenase maturation protease K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
D AFE_1778 guaA; GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D AFE_2530 conserved hypothetical protein K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D AFE_2528 glutamine amidotransferase, class I K07010 K07010; putative glutamine amidotransferase
D AFE_2167 toxin secretion ABC transporter, ATP-binding protein, HlyB family K13409 cvaB; ATP-binding cassette, subfamily B, bacterial CvaB/MchF/RaxB
D AFE_2064 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D AFE_0730 gltB; glutamate synthase, large subunit K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
D AFE_3200 glmS; glucosamine--fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D AFE_1353 asnB; asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D AFE_2005 isonitrile hydratase, putative K18199 inhA; cyclohexyl-isocyanide hydratase [EC:4.2.1.103]
D AFE_0382 ErfK/YbiS/YcfS/YnhG family protein K16291 erfK; L,D-transpeptidase ErfK/SrfK
D AFE_2572 ErfK/YbiS/YcfS/YnhG family protein K16291 erfK; L,D-transpeptidase ErfK/SrfK
D AFE_1873 pepN; aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D AFE_2674 oligoendopeptidase F, putative K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
D AFE_0462 d-alanyl-d-alanine dipeptidase, putative K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
D AFE_2201 pepA; cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D AFE_1819 dapE; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D AFE_0925 map; methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D AFE_2815 pepP; Xaa-Pro aminopeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D AFE_2636 ftsH; cell division protein FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D AFE_2090 peptidase, M48 family K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D AFE_0247 htpX-2; heat shock protein HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D AFE_1114 htpX-1; heat shock protein HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D AFE_1451 membrane-associated zinc metalloprotease, putative K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
D AFE_1646 serine protease, DO/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107]
D AFE_1396 serine protease, DO/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107]
D AFE_2567 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D AFE_2350 D-alanyl-D-alanine carboxypeptidase, putative K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D AFE_2923 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D AFE_2172 beta-lactamase K21469 pbp4b; serine-type D-Ala-D-Ala carboxypeptidase [EC:3.4.16.4]
D AFE_1960 dacB; D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
D AFE_0910 clpP; ATP-dependent Clp protease, proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D AFE_0872 lon-2; ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D AFE_0912 lon-1; ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D AFE_1868 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D AFE_1750 umuD; umuD protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D AFE_1398 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D AFE_0524 ctpA; carboxy-terminal peptidase K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
D AFE_0806 penicillin amidase family protein K01434 pac; penicillin G amidase [EC:3.5.1.11]
D AFE_2080 sppA; signal peptide peptidase SppA, 67K type K04773 sppA; protease IV [EC:3.4.21.-]
D AFE_0973 type IV pilin biogenesis peptidase, putative K04774 sohB; serine protease SohB [EC:3.4.21.-]
D AFE_2747 hslV; heat shock protein HslV K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
D AFE_0785 ggt; gamma-glutamyltranspeptidase K22602 hpxW; oxamate amidohydrolase [EC:3.5.1.126]
D AFE_2722 yhbV; peptidase, U32 family K24845 ubiV; O2-independent ubiquinone biosynthesis protein UbiV
D AFE_2723 peptidase, U32 family K24844 ubiU; O2-independent ubiquinone biosynthesis protein UbiU
D AFE_0600 pmbA; pmbA protein K03592 pmbA; PmbA protein
D AFE_2637 tldD; tldD protein K03568 tldD; TldD protein
D AFE_2253 conserved hypothetical protein K06894 yfhM; alpha-2-macroglobulin
D AFE_1887 hflC; hflC protein K04087 hflC; modulator of FtsH protease HflC
D AFE_1886 hflK; hflK protein K04088 hflK; modulator of FtsH protease HflK
C 01003 Glycosyltransferases [BR:afr01003]
D AFE_2121 glycosyl transferase, group 2 family protein K00720 UGCG; ceramide glucosyltransferase [EC:2.4.1.80]
D AFE_1427 glycosyl transferase, group 1 family protein K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]
D AFE_2678 glgA; glycogen synthase K00703 glgA; starch synthase [EC:2.4.1.21]
D AFE_2254 penicillin-binding protein 1C, putative K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]
D AFE_2223 penicillin-binding protein 1A, putative K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D AFE_0962 mdoH; periplasmic glucans biosynthesis protein MdoH K03669 mdoH; membrane glycosyltransferase [EC:2.4.1.-]
D AFE_1552 sucrose synthase, putative K00695 SUS; sucrose synthase [EC:2.4.1.13]
C 01005 Lipopolysaccharide biosynthesis proteins [BR:afr01005]
D AFE_1456 lpxA; acyl-(acyl-carrier-protein)-UDP-N-acetylglucosamine acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
D AFE_1459 lpxB; lipid A disaccharide synthase LpxB K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]
D AFE_0223 lpxC; UDP-3-0-acyl N-acetylglucosamine deacetylase K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]
D AFE_1454 lpxD; UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]
D AFE_1987 lpxH; UDP-2,3-diacylglucosamine hydrolase K03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]
D AFE_0489 lpxK; tetraacyldisaccharide 4'-kinase K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]
D AFE_0238 lipid A biosynthesis lauroyl acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-]
D AFE_0237 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]
D AFE_2677 3-deoxy-D-manno-octulosonic-acid transferase domain protein K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]
D AFE_0258 hypothetical protein K12976 pagL; lipid A 3-O-deacylase [EC:3.1.1.-]
D AFE_1831 hypothetical protein K12976 pagL; lipid A 3-O-deacylase [EC:3.1.1.-]
D AFE_0848 kdsA; 3-deoxy-8-phosphooctulonate synthase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]
D AFE_0491 kdsB; 3-deoxy-D-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]
D AFE_3029 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]
D AFE_3030 sugar isomerase, KpsF/GutQ family K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]
D AFE_1406 kinase, pfkB family K21344 rfaE1; D-glycero-beta-D-manno-heptose-7-phosphate kinase [EC:2.7.1.167]
D AFE_0235 rfaC; lipopolysaccharide heptosyltransferase 1 K02841 waaC; lipopolysaccharide heptosyltransferase I [EC:2.4.99.23]
D AFE_0138 LPS heptosyltransferase II K02843 waaF; lipopolysaccharide heptosyltransferase II [EC:2.4.99.24]
D AFE_0232 O-antigen polymerase family protein K02847 waaL; O-antigen ligase [EC:2.4.99.26]
D AFE_0714 gmhA; phosphoheptose isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
D AFE_2582 histidinol-phosphate phosphatase domain protein K03273 gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83]
D AFE_1967 rfaD; ADP-L-glycero-D-mannoheptose-6-epimerase K03274 gmhD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20]
D AFE_1776 glycosyl transferase K20534 gtrB; polyisoprenyl-phosphate glycosyltransferase [EC:2.4.-.-]
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:afr01011]
D AFE_3039 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D AFE_0204 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D AFE_0205 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D AFE_0208 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D AFE_0211 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D AFE_0203 ddlB; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D AFE_2818 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D AFE_2842 murI; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
D AFE_0209 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D AFE_0206 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D AFE_0636 undecaprenol kinase, putative K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D AFE_0559 mviN; integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase
D AFE_2223 penicillin-binding protein 1A, putative K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D AFE_2254 penicillin-binding protein 1C, putative K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]
D AFE_2565 mrdA; penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D AFE_2144 penicillin-binding protein 2, putative K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D AFE_2895 peptidoglycan synthetase FtsI, putative K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D AFE_0212 ftsI; peptidoglycan synthetase FtsI K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D AFE_2567 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D AFE_2350 D-alanyl-D-alanine carboxypeptidase, putative K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D AFE_2923 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D AFE_1960 dacB; D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
D AFE_2172 beta-lactamase K21469 pbp4b; serine-type D-Ala-D-Ala carboxypeptidase [EC:3.4.16.4]
D AFE_0382 ErfK/YbiS/YcfS/YnhG family protein K16291 erfK; L,D-transpeptidase ErfK/SrfK
D AFE_2572 ErfK/YbiS/YcfS/YnhG family protein K16291 erfK; L,D-transpeptidase ErfK/SrfK
D AFE_0462 d-alanyl-d-alanine dipeptidase, putative K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
D AFE_0941 murein transglycosylase, putative K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
D AFE_1827 membrane-bound lytic murein transglycosylase B, putative K08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29]
D AFE_0421 mltD; membrane-bound lytic murein transglycosylase D K08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]
D AFE_2921 rare lipoprotein A, putative K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
D AFE_1818 rare lipoprotein A, putative K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
D AFE_2361 N-acetylmuramoyl-L-alanine amidase, putative K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D AFE_2589 ampD; ampD protein K03806 ampD; N-acetyl-anhydromuramoyl-L-alanine amidase [EC:3.5.1.28]
C 01004 Lipid biosynthesis proteins [BR:afr01004]
D AFE_1907 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D AFE_1906 fabH; 3-oxoacyl-(acyl-carrier-protein) synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D AFE_0796 3-oxoacyl-(acyl-carrier-protein) synthase, putative K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]
D AFE_1910 fabF; 3-oxoacyl-(acyl-carrier-protein) synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D AFE_0793 3-oxoacyl-(acyl-carrier-protein) reductase, putative K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D AFE_1908 fabG; 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D AFE_1455 fabZ; beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D AFE_0420 fabI; enoyl-(acyl-carrier-protein) reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D AFE_1964 fatty acid desaturase K10255 FAD6; acyl-lipid omega-6 desaturase (Delta-12 desaturase) [EC:1.14.19.23 1.14.19.45]
D AFE_1969 acs; acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D AFE_0220 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D AFE_1905 plsX; fatty acid/phospholipid synthesis protein PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D AFE_0125 membrane protein, putative K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D AFE_0058 acyltransferase family protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D AFE_2584 acyltransferase family protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:afr01006]
D AFE_1975 ispA; geranyltranstransferase K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
D AFE_2899 ispB; octaprenyl-diphosphate synthase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D AFE_1448 uppS; undecaprenyl diphosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D AFE_2125 phytoene/squalene synthetase family protein K10208 crtM; 4,4'-diapophytoene synthase [EC:2.5.1.96]
D AFE_1928 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D AFE_0592 ubiA; 4-hydroxybenzoate polyprenyl transferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D AFE_0635 cyoE-1; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D AFE_3143 cyoE-2; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
C 01007 Amino acid related enzymes [BR:afr01007]
D AFE_0422 gltX-2; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D AFE_2222 gltX-1; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
D AFE_0927 glutamyl-tRNA synthetase-related protein K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
D AFE_3085 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D AFE_1789 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D AFE_2221 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D AFE_0170 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D AFE_2672 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D AFE_0556 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D AFE_2204 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D AFE_0459 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D AFE_0480 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D AFE_0056 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D AFE_1934 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D AFE_2580 glyQ; glycyl-tRNA synthetase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D AFE_2581 glyS; glycyl-tRNA synthetase, beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D AFE_0380 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D AFE_2132 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D AFE_2614 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D AFE_0934 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D AFE_2610 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D AFE_2609 pheT; phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D AFE_2022 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D AFE_0472 aminotransferase, class I/II K14261 alaC; alanine-synthesizing transaminase [EC:2.6.1.-]
D AFE_1821 aminotransferase, classes I and II K14267 dapC; N-succinyldiaminopimelate aminotransferase [EC:2.6.1.17]
D AFE_0898 hisC-2; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D AFE_3042 hisC-1; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D AFE_0243 bioF; 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D AFE_3011 8-amino-7-oxononanoate synthase, putative K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D AFE_0239 aminotransferase, class II K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D AFE_0406 argD; acetylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D AFE_1924 bioA; adenosylmethionine-8-amino-7-oxononanoate aminotransferase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
D AFE_3303 hemL; glutamate-1-semialdehyde-2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D AFE_0547 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D AFE_0895 serC; phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
D AFE_1540 aminotransferase, DegT/DnrJ/EryC1/StrS family K13010 per; perosamine synthetase [EC:2.6.1.102]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:afr00194]
D AFE_3202 atpC; ATP synthase F1, epsilon subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D AFE_2423 ATP synthase F1, epsilon subunit, putative K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D AFE_0758 ATP synthase F1, epsilon subunit, putative K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D AFE_3203 atpD; ATP synthase F1, beta subunit K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D AFE_3204 atpG; ATP synthase F1, gamma subunit K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D AFE_3205 atpA; ATP synthase F1, alpha subunit K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D AFE_3206 atpH; ATP synthase F1, delta subunit K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D AFE_3207 atpF; ATP synthase F0, B subunit K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D AFE_3208 atpE; ATP synthase F0, C subunit K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D AFE_3209 atpB; ATP synthase F0, A subunit K02108 ATPF0A; F-type H+-transporting ATPase subunit a
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:afr03000]
D AFE_2799 transcriptional regulator, Ada family/DNA-3-methyladenine glycosylase II K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D AFE_0879 transcriptional regulator, LysR family K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator
D AFE_0135 transcriptional regulator, LysR family K03576 metR; LysR family transcriptional regulator, regulator for metE and metH
D AFE_0699 cysB; sulfur assimilation transcriptional regulator, LysR family K13634 cysB; LysR family transcriptional regulator, cys regulon transcriptional activator
D AFE_1296 transcriptional regulator, LysR family K13634 cysB; LysR family transcriptional regulator, cys regulon transcriptional activator
D AFE_0866 transcriptional regulator, LysR family K21703 cbbR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator
D AFE_1993 transcriptional regulator, LysR family K21703 cbbR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator
D AFE_0172 transcriptional regulator, LysR family K21703 cbbR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator
D AFE_1692 cbbR; rubisco operon transcriptional regulator K21703 cbbR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator
D AFE_2158 transcriptional regulator, LysR family K21703 cbbR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator
D AFE_0817 transcriptional regulator, LysR family K21711 pycR; LysR family transcriptional regulator, putative pyruvate carboxylase regulator
D AFE_2287 transcriptional regulator, GntR family K02043 phnF; GntR family transcriptional regulator, phosphonate transport system regulatory protein
D AFE_0255 transcriptional regulator, TetR family K09017 rutR; TetR/AcrR family transcriptional regulator
D AFE_2209 transcriptional regulator, TetR family K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D AFE_1990 transcriptional regulator, AsnC family K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D AFE_2185 transcriptional regulator, MarR family K06075 slyA; MarR family transcriptional regulator, transcriptional regulator for hemolysin
D AFE_0373 transcriptional regulator, MerR family K19591 cueR; MerR family transcriptional regulator, copper efflux regulator
D AFE_1467 transcriptional regulator, Fur family K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D AFE_0282 fur; ferric uptake regulation protein K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D AFE_1955 transcriptional regulator, Fur family K09826 irr; Fur family transcriptional regulator, iron response regulator
D AFE_1668 transcriptional regulator, IclR family K13641 iclR; IclR family transcriptional regulator, acetate operon repressor
D AFE_2344 cyclic nucleotide-binding domain protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D AFE_0119 transcriptional regulator, Crp/Fnr family K01420 fnr; CRP/FNR family transcriptional regulator, anaerobic regulatory protein
D AFE_0270 transcriptional regulator, Crp/Fnr family K01420 fnr; CRP/FNR family transcriptional regulator, anaerobic regulatory protein
D AFE_1658 transcriptional regulator, Crp/Fnr family K21563 dnr; CRP/FNR family transcriptional regulator, dissimilatory nitrate respiration regulator
D AFE_0857 transcriptional regulator, Crp/Fnr family K21563 dnr; CRP/FNR family transcriptional regulator, dissimilatory nitrate respiration regulator
D AFE_0672 iscR; iron-sulfur cluster assembly transcription factor IscR K13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor
D AFE_3240 Rrf2 family protein K13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor
D AFE_3141 Rrf2 family protein K13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor
D AFE_2859 arsR; transcriptional regulator, ArsR K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D AFE_0453 birA; birA bifunctional protein K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D AFE_0191 transcriptional regulator, Fis family K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
D AFE_1741 sigma-54 dependent transcriptional regulator K21405 acoR; sigma-54 dependent transcriptional regulator, acetoin dehydrogenase operon transcriptional activator AcoR
D AFE_0693 sigma-54 dependent transcriptional regulator K21405 acoR; sigma-54 dependent transcriptional regulator, acetoin dehydrogenase operon transcriptional activator AcoR
D AFE_1527 nifA; Nif-specific regulatory protein K02584 nifA; Nif-specific regulatory protein
D AFE_0723 helix-turn-helix domain protein K02019 modE; molybdate transport system regulatory protein
D AFE_0665 BolA family protein K05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator
D AFE_3211 parB family protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D AFE_1719 parB family protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D AFE_2667 hrcA; heat-inducible transcription repressor HrcA K03705 hrcA; heat-inducible transcriptional repressor
D AFE_0437 ACT domain protein K03567 gcvR; glycine cleavage system transcriptional repressor
D AFE_3060 pyrR; PyrR bifunctional protein K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]
D AFE_2006 transcriptional regulator, putative K07734 paiB; transcriptional regulator
D AFE_2807 transcriptional regulator, putative K07734 paiB; transcriptional regulator
D AFE_3062 conserved hypothetical protein K07735 algH; putative transcriptional regulator
D AFE_1465 dksA; dnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
D AFE_0296 nrdR; transcriptional regulator, NrdR family K07738 nrdR; transcriptional repressor NrdR
D AFE_0215 mraZ; mraZ protein K03925 mraZ; transcriptional regulator MraZ
C 03021 Transcription machinery [BR:afr03021]
D AFE_0354 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D AFE_0320 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D AFE_0321 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D AFE_0564 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D AFE_2336 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor
D AFE_0470 rpoS; RNA polymerase sigma-38 factor K03087 rpoS; RNA polymerase nonessential primary-like sigma factor
D AFE_1833 RNA polymerase sigm-70 factor family K03087 rpoS; RNA polymerase nonessential primary-like sigma factor
D AFE_2342 RNA polymerase sigm-70 factor family K03087 rpoS; RNA polymerase nonessential primary-like sigma factor
D AFE_1394 rpoE; RNA polymerase sigma-E factor K03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily
D AFE_2750 rpoH; RNA polymerase sigma-32 factor K03089 rpoH; RNA polymerase sigma-32 factor
D AFE_3025 rpoN; RNA polymerase sigma-54 factor K03092 rpoN; RNA polymerase sigma-54 factor
D AFE_0390 nusA; transcription termination factor NusA K02600 nusA; transcription termination/antitermination protein NusA
D AFE_0301 nusB; transcription antitermination factor NusB K03625 nusB; transcription antitermination protein NusB
D AFE_0314 nusG; transcription termination/antitermination factor NusG K02601 nusG; transcription termination/antitermination protein NusG
D AFE_0221 sspA; stringent starvation protein A K03599 sspA; stringent starvation protein A
D AFE_0190 sspB; stringent starvation protein B K03600 sspB; stringent starvation protein B
D AFE_1465 dksA; dnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
D AFE_0638 greA; transcription elongation factor GreA K03624 greA; transcription elongation factor GreA
D AFE_0658 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D AFE_0381 conserved hypothetical protein K19000 rof; Rho-binding antiterminator
C 03019 Messenger RNA biogenesis [BR:afr03019]
D AFE_2220 ribonuclease, Rne/Rng family K08300 rne; ribonuclease E [EC:3.1.26.12]
D AFE_2954 ribonuclease, Rne/Rng family K08301 rng; ribonuclease G [EC:3.1.26.-]
D AFE_1400 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D AFE_1891 vacB; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D AFE_2320 orn; oligoribonuclease Orn K13288 orn; oligoribonuclease [EC:3.1.-.-]
D AFE_1433 rhlE; ATP-dependent RNA helicase RhlE K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]
D AFE_0589 ATP-dependent RNA helicase, DEAD/DEAH box family K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D AFE_2194 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D AFE_0849 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D AFE_0395 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D AFE_0658 rho; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D AFE_2665 dnaK; chaperone protein Dnak K04043 dnaK; molecular chaperone DnaK
D AFE_0542 groEL; chaperonin, 60 kDa K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D AFE_1884 hfq; RNA chaperone Hfq K03666 hfq; host factor-I protein
D AFE_1876 ppk; polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
D AFE_1892 conserved hypothetical protein K22468 ppk2; polyphosphate kinase [EC:2.7.4.34]
D AFE_1775 pcnB; polyA polymerase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
D AFE_2173 NUDIX hydrolase K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]
D AFE_3021 ATPase K06958 rapZ; RNase adapter protein RapZ
C 03041 Spliceosome
C 03011 Ribosome [BR:afr03011]
D AFE_0903 rpsA; ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D AFE_1444 rpsB; ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D AFE_0333 rpsC; ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D AFE_0353 rpsD; ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D AFE_0344 rpsE; ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D AFE_2824 rpsF; ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D AFE_0323 rpsG; ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D AFE_0341 rpsH; ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D AFE_3074 rpsI; ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D AFE_0326 rpsJ; ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D AFE_0352 rpsK; ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D AFE_0322 rpsL; ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D AFE_0351 rpsM; ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D AFE_0340 rpsN; ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D AFE_0394 rpsO; ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D AFE_2855 rpsP; ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D AFE_0336 rpS17; ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D AFE_2823 rpS18; ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D AFE_0331 rpsS; ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D AFE_2188 rpsT; ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D AFE_2340 rpsU; ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D AFE_0316 rplA; ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D AFE_0330 rplB; ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D AFE_0327 rplC; ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D AFE_0328 rplD; ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D AFE_0339 rplE; ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D AFE_0342 rplF; ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D AFE_2820 rplI; ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D AFE_0317 rplJ; ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D AFE_0315 rplK; ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D AFE_0318 rplL; ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D AFE_3075 rplM; ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D AFE_0337 rplN; ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D AFE_0346 rplO; ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D AFE_0334 rplP; ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D AFE_0355 rplQ; ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D AFE_0343 rplR; ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D AFE_2852 rplS; ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D AFE_2611 rplT; ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D AFE_0285 rplU; ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D AFE_0332 rplV; ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D AFE_0329 rplW; ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D AFE_0338 rplX; ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D AFE_0284 rpmA; ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D AFE_2670 rpmB; ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D AFE_0335 rpmC; ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D AFE_0345 rpmD; ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D AFE_0659 rpmE; ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D AFE_1904 rpmF; ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D AFE_2669 rpmG; ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D AFE_0035 rpmH; ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D AFE_2612 rpmI; ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D AFE_0350 rpmJ; ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D AFE_2145 rplY; ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D AFE_0388 rrfB; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D AFE_3080 rrfA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D AFE_0384 rrsB; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D AFE_3084 rrsA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D AFE_0387 rrlB; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D AFE_3081 rrlA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:afr03009]
D AFE_1400 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D AFE_2320 orn; oligoribonuclease Orn K13288 orn; oligoribonuclease [EC:3.1.-.-]
D AFE_1401 era; GTP-binding protein Era K03595 era; GTPase
D AFE_0283 GTP-binding protein Obg/CgtA K03979 obgE; GTPase [EC:3.6.5.-]
D AFE_1465 dksA; dnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
D AFE_0390 nusA; transcription termination factor NusA K02600 nusA; transcription termination/antitermination protein NusA
D AFE_0301 nusB; transcription antitermination factor NusB K03625 nusB; transcription antitermination protein NusB
D AFE_0314 nusG; transcription termination/antitermination factor NusG K02601 nusG; transcription termination/antitermination protein NusG
D AFE_2175 rsuA; ribosomal small subunit pseudouridine synthase A K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]
D AFE_0167 ksgA; dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D AFE_0021 sun; sun protein K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D AFE_2754 methyltransferase, putative K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]
D AFE_3257 conserved hypothetical protein TIGR00046 K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]
D AFE_3213 gidB; methyltransferase GidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D AFE_0214 mraW; S-adenosyl-methyltransferase MraW K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D AFE_0144 tetrapyrrole methylase family protein K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]
D AFE_0991 tRNA (guanosine-2'-O-)-methyltransferase, putative K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]
D AFE_2736 rrmJ; ribosomal RNA large subunit methyltransferase J K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
D AFE_2950 conserved hypothetical protein K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]
D AFE_0892 conserved hypothetical protein K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]
D AFE_0176 conserved hypothetical protein K07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266]
D AFE_1930 radical SAM enzyme, Cfr family K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]
D AFE_2828 rumA; 23S rRNA (uracil-5-)-methyltransferase K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]
D AFE_2348 RNA pseudouridine synthase family protein K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]
D AFE_1793 rluB; ribosomal large subunit pseudouridine synthase B K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]
D AFE_2219 rluC; ribosomal large subunit pseudouridine synthase C K06179 rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24]
D AFE_0431 rluD; ribosomal large subunit pseudouridine synthase D K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D AFE_2515 rimI; ribosomal-protein-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D AFE_2467 acetyltransferase, GNAT family K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D AFE_2583 alpha-L-glutamate ligase, RimK family K05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]
D AFE_2854 rimM; 16S rRNA processing protein RimM K02860 rimM; 16S rRNA processing protein RimM
D AFE_0127 MiaB-like tRNA modifying enzyme YliG, putative K14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]
D AFE_2097 hypothetical protein K09136 ycaO; ribosomal protein S12 methylthiotransferase accessory factor
D AFE_0194 prmA; ribosomal protein L11 methyltransferase K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]
D AFE_0173 prmB; ribosomal protein L3 N-methyltransferase K07320 prmB; ribosomal protein L3 glutamine methyltransferase [EC:2.1.1.298]
D AFE_2220 ribonuclease, Rne/Rng family K08300 rne; ribonuclease E [EC:3.1.26.12]
D AFE_2954 ribonuclease, Rne/Rng family K08301 rng; ribonuclease G [EC:3.1.26.-]
D AFE_3061 conserved hypothetical protein K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]
D AFE_0589 ATP-dependent RNA helicase, DEAD/DEAH box family K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D AFE_1937 engA; ribosome-associated GTPase EngA K03977 engA; GTPase
D AFE_1885 hflX; GTP-binding protein HflX K03665 hflX; GTPase
D AFE_2262 Sua5/YciO/YrdC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D AFE_1674 Sua5/YciO/YrdC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D AFE_0565 spoT; guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D AFE_0392 rbfA; ribosome-binding factor A K02834 rbfA; ribosome-binding factor A
D AFE_0389 lipoprotein, putative K09748 rimP; ribosome maturation factor RimP
D AFE_2949 iojap-related protein K09710 ybeB; ribosome-associated protein
D AFE_0598 conserved hypothetical protein TIGR00043 K07042 ybeY; probable rRNA maturation factor
D AFE_2737 conserved hypothetical protein K07574 yhbY; RNA-binding protein
D AFE_3024 yfiA; ribosomal subunit interface protein K05808 hpf; ribosome hibernation promoting factor
D AFE_2147 ychF; GTP-binding protein YchF K06942 ychF; ribosome-binding ATPase
D AFE_1903 hypothetical protein K07040 yceD; DUF177 domain-containing protein
C 03016 Transfer RNA biogenesis [BR:afr03016]
D AFE_0218 polyA polymerase family protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
D AFE_1774 polyA polymerase family protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
D AFE_0422 gltX-2; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D AFE_2132 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D AFE_0556 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D AFE_0459 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D AFE_2672 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D AFE_0170 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D AFE_0480 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D AFE_0056 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D AFE_0934 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D AFE_2614 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D AFE_0380 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D AFE_2221 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D AFE_2204 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D AFE_1934 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D AFE_2610 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D AFE_2609 pheT; phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D AFE_3085 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D AFE_1789 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D AFE_3302 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D AFE_0271 trmB; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D AFE_2071 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D AFE_0393 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D AFE_0372 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D AFE_1537 iscS-1; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D AFE_0673 iscS-3; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D AFE_1507 iscS-2; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D AFE_2262 Sua5/YciO/YrdC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D AFE_1674 Sua5/YciO/YrdC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D AFE_1928 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D AFE_0031 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D AFE_3214 gidA; glucose-inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D AFE_2973 cysQ; 3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
D AFE_0034 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D AFE_0216 sRNA K01978 rnpB; M1 RNA
D AFE_0217 Bacterial RNase P class A K01978 rnpB; M1 RNA
D AFE_0251 rnt; ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-]
D AFE_2343 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D AFE_0036 ABC transporter, ATP-binding protein K06020 ettA; energy-dependent translational throttle protein EttA
D AFE_2580 glyQ; glycyl-tRNA synthetase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D AFE_2581 glyS; glycyl-tRNA synthetase, beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D AFE_0927 glutamyl-tRNA synthetase-related protein K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
D AFE_2222 gltX-1; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
D AFE_0741 cytidine and deoxycytidylate deaminase family protein K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
D AFE_2027 dusA; tRNA-dihydrouridine synthase A K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
D AFE_0596 miaB; tRNA-i(6)A37 modification enzyme MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
D AFE_2853 trmD; tRNA (guanine-N1)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D AFE_0670 RNA methyltransferase, TrmH family, group 1 K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D AFE_0241 RNA methyltransferase, TrmH family, group 2 K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D AFE_0680 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D AFE_1407 PP-loop family protein K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D AFE_2557 conserved hypothetical protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D AFE_0675 iscA; iron-sulfur cluster assembly protein IscA K13628 iscA; iron-sulfur cluster assembly protein
D AFE_1531 iron-sulfur cluster assembly accessory protein K13628 iscA; iron-sulfur cluster assembly protein
D AFE_1391 ygfZ; folate-binding protein YgfZ K06980 ygfZ; tRNA-modifying protein YgfZ
D AFE_2060 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D AFE_0068 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D AFE_0069 radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D AFE_0752 GTP cyclohydrolase I family protein K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D AFE_2588 conserved hypothetical protein K09765 queH; epoxyqueuosine reductase [EC:1.17.99.6]
D AFE_2059 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D AFE_1464 tilS; tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D AFE_2516 conserved hypothetical protein K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D AFE_0123 gcp; O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D AFE_1926 conserved hypothetical protein TIGR00150 K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D AFE_2386 HesA/MoeB/ThiF family protein K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
D AFE_1891 vacB; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D AFE_0395 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D AFE_2655 PIN domain protein K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D AFE_2129 virulence-associated protein, putative K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D AFE_0478 virulence-associated protein, putative K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
C 03012 Translation factors [BR:afr03012]
D AFE_0391 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D AFE_2613 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D AFE_1445 tsf; translation elongation factor Ts K02357 tsf; elongation factor Ts
D AFE_0311 tuf-2; translation elongation factor Tu K02358 tuf; elongation factor Tu
D AFE_0325 tuf-1; translation elongation factor Tu K02358 tuf; elongation factor Tu
D AFE_0324 fusA; translation elongation factor G K02355 fusA; elongation factor G
D AFE_2760 prfA; peptide chain release factor 1 K02835 prfA; peptide chain release factor 1
D AFE_1447 frr; ribosome recycling factor K02838 frr; ribosome recycling factor
D AFE_2759 modification methylase, HemK family K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D AFE_2146 pth; peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]
D AFE_0349 infA; translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1
D AFE_0851 efp; translation elongation factor P K02356 efp; elongation factor P
D AFE_0479 prfB; peptide chain release factor 2, programmed frameshift K02836 prfB; peptide chain release factor 2
D AFE_2514 prfC; peptide chain release factor 3 K02837 prfC; peptide chain release factor 3
C 03110 Chaperones and folding catalysts [BR:afr03110]
D AFE_0520 clpA; ATP-dependent Clp protease, ATP-binding subunit ClpA K03694 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA
D AFE_1970 clpB; clpB protein K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
D AFE_0911 clpX; ATP-dependent Clp protease, ATP-binding subunit ClpX K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
D AFE_2748 hslU; heat shock protein HslVU, ATPase subunit HslU K03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU
D AFE_3158 htpG; heat shock protein HtpG K04079 HSP90A; molecular chaperone HtpG
D AFE_2665 dnaK; chaperone protein Dnak K04043 dnaK; molecular chaperone DnaK
D AFE_0677 hscA; Fe-S protein assembly chaperone HscA K04044 hscA; molecular chaperone HscA
D AFE_0542 groEL; chaperonin, 60 kDa K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D AFE_2664 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D AFE_3102 cbpA; curved DNA-binding protein K05516 cbpA; curved DNA-binding protein
D AFE_0676 hscB; co-chaperone Hsc20 K04082 hscB; molecular chaperone HscB
D AFE_1408 hslO; 33 kDa chaperonin K04083 hslO; molecular chaperone Hsp33
D AFE_2666 grpE; co-chaperone GrpE K03687 GRPE; molecular chaperone GrpE
D AFE_1648 heat shock protein, Hsp20 family K13993 HSP20; HSP20 family protein
D AFE_2086 heat shock protein, Hsp20 family K13993 HSP20; HSP20 family protein
D AFE_0871 heat shock protein, Hsp20 family K13993 HSP20; HSP20 family protein
D AFE_0543 groES; chaperonin, 10 kDa K04078 groES; chaperonin GroES
D AFE_1646 serine protease, DO/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107]
D AFE_1396 serine protease, DO/DeqQ family K04771 degP; serine protease Do [EC:3.4.21.107]
D AFE_2636 ftsH; cell division protein FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D AFE_3209 atpB; ATP synthase F0, A subunit K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D AFE_0006 pilus chaperone protein, putative K07346 fimC; fimbrial chaperone protein
D AFE_2127 secB; preprotein translocase, SecB subunit K03071 secB; preprotein translocase subunit SecB
D AFE_3287 hypA-2; hydrogenase nickel insertion protein HypA K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF
D AFE_0717 hypA-1; hydrogenase nickel insertion protein HypA K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF
D AFE_3288 hypB-2; hydrogenase accessory protein HypB K04652 hypB; hydrogenase nickel incorporation protein HypB
D AFE_0718 hypB-1; hydrogenase accessory protein HypB K04652 hypB; hydrogenase nickel incorporation protein HypB
D AFE_2181 sreD; sulfur reductase K23349 dmsD; putative dimethyl sulfoxide reductase chaperone
D AFE_1986 ppiB; peptidyl-prolyl cis-trans isomerase B K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D AFE_0180 peptidyl-prolyl cis-trans isomerase, FKBP-type K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]
D AFE_0522 peptidyl-prolyl cis-trans isomerase, PPIC-type K03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]
D AFE_3035 surA; survival protein SurA K03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8]
D AFE_0657 trx; thioredoxin K03671 TXN; thioredoxin
D AFE_1979 thioredoxin K03671 TXN; thioredoxin
D AFE_2590 thioredoxin, putative K03671 TXN; thioredoxin
D AFE_2362 thioredoxin K03672 trxC; thioredoxin 2 [EC:1.8.1.8]
D AFE_2848 thioredoxin, putative K05838 ybbN; putative thioredoxin
D AFE_2363 grxC; glutaredoxin 3 K03676 grxC; glutaredoxin 3
D AFE_2449 conserved hypothetical protein K03676 grxC; glutaredoxin 3
D AFE_3038 glutaredoxin-related protein K07390 grxD; monothiol glutaredoxin
D AFE_1088 thiol:disulfide interchange protein, DsbA family K03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15]
D AFE_0545 dsbD; thiol:disulfide interchange protein DsbD K04084 dsbD; thioredoxin:protein disulfide reductase [EC:1.8.4.16]
D AFE_1872 thiol:disulfide interchange protein, putative K03805 dsbG; thiol:disulfide interchange protein DsbG
D AFE_2947 thiol:disulfide interchange protein DsbG, putative K03805 dsbG; thiol:disulfide interchange protein DsbG
D AFE_1943 dsbG domain protein K03805 dsbG; thiol:disulfide interchange protein DsbG
D AFE_1018 thiol:disulfide interchange domain protein K03805 dsbG; thiol:disulfide interchange protein DsbG
D AFE_1085 thiol:disulfide interchange domain protein K03805 dsbG; thiol:disulfide interchange protein DsbG
D AFE_2246 dsbG domain protein K03805 dsbG; thiol:disulfide interchange protein DsbG
D AFE_0275 thiol:disulfide interchange domain protein K03805 dsbG; thiol:disulfide interchange protein DsbG
C 04131 Membrane trafficking [BR:afr04131]
D AFE_1929 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D AFE_3251 gap; glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D AFE_0749 pyruvate kinase barrel domain protein K00873 PK; pyruvate kinase [EC:2.7.1.40]
D AFE_1801 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D AFE_3249 pykA; pyruvate kinase II K00873 PK; pyruvate kinase [EC:2.7.1.40]
D AFE_3158 htpG; heat shock protein HtpG K04079 HSP90A; molecular chaperone HtpG
C 04121 Ubiquitin system [BR:afr04121]
C 03051 Proteasome [BR:afr03051]
D AFE_3158 htpG; heat shock protein HtpG K04079 HSP90A; molecular chaperone HtpG
C 03032 DNA replication proteins [BR:afr03032]
D AFE_0399 rnhA-2; ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D AFE_1199 rnhA-1; ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D AFE_1241 DNA-binding protein HU family protein K03530 hupB; DNA-binding protein HU-beta
D AFE_1584 DNA-binding protein HU family protein K03530 hupB; DNA-binding protein HU-beta
D AFE_2471 DNA-binding protein HU family protein K03530 hupB; DNA-binding protein HU-beta
D AFE_0914 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D AFE_1070 DNA-binding protein, HU family K04764 ihfA; integration host factor subunit alpha
D AFE_1583 integration host factor, alpha subunit, putative K04764 ihfA; integration host factor subunit alpha
D AFE_1586 DNA-binding protein, HU family K04764 ihfA; integration host factor subunit alpha
D AFE_2608 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
D AFE_0905 ihfB; integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
D AFE_3309 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D AFE_2819 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D AFE_1566 DNA replication protein DnaC, putative K02315 dnaC; DNA replication protein DnaC
D AFE_2337 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D AFE_1569 ssb-2; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_2845 ssb-1; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_1260 ssb-3; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_1461 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D AFE_0001 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D AFE_2203 holC; DNA polymerase III, chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
D AFE_0457 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D AFE_1914 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D AFE_0400 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D AFE_1919 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D AFE_1460 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D AFE_3094 polI; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D AFE_0757 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D AFE_1230 DNA ligase, NAD-dependent, putative K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D AFE_1568 methyltransferase, putative K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D AFE_1901 conserved hypothetical protein K10763 hda; DnaA-homolog protein
D AFE_0894 gyrA; DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D AFE_0003 gyrB; DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D AFE_2028 parC; DNA topoisomerase IV, A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D AFE_2029 parE; DNA topoisomerase IV, subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D AFE_0015 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D AFE_1013 DNA topoisomerase I, putative K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D AFE_1738 topB; DNA topoisomerase III K03169 topB; DNA topoisomerase III [EC:5.6.2.1]
D AFE_1258 DNA topoisomerase domain protein K03169 topB; DNA topoisomerase III [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:afr03036]
D AFE_1400 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D AFE_1241 DNA-binding protein HU family protein K03530 hupB; DNA-binding protein HU-beta
D AFE_1584 DNA-binding protein HU family protein K03530 hupB; DNA-binding protein HU-beta
D AFE_2471 DNA-binding protein HU family protein K03530 hupB; DNA-binding protein HU-beta
D AFE_0914 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D AFE_1070 DNA-binding protein, HU family K04764 ihfA; integration host factor subunit alpha
D AFE_1583 integration host factor, alpha subunit, putative K04764 ihfA; integration host factor subunit alpha
D AFE_1586 DNA-binding protein, HU family K04764 ihfA; integration host factor subunit alpha
D AFE_2608 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
D AFE_0905 ihfB; integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
D AFE_3102 cbpA; curved DNA-binding protein K05516 cbpA; curved DNA-binding protein
D AFE_3309 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D AFE_0191 transcriptional regulator, Fis family K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
D AFE_1884 hfq; RNA chaperone Hfq K03666 hfq; host factor-I protein
D AFE_1990 transcriptional regulator, AsnC family K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D AFE_0753 smc; chromosome segregation protein SMC K03529 smc; chromosome segregation protein
D AFE_1790 scpA; segregation and condensation protein A K05896 scpA; segregation and condensation protein A
D AFE_1791 scpB; segregation and condensation protein B K06024 scpB; segregation and condensation protein B
D AFE_0201 ftsA; cell division protein FtsA K03590 ftsA; cell division protein FtsA
D AFE_0850 septum formation initiator family protein K05589 ftsB; cell division protein FtsB
D AFE_2752 ftsE; cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein
D AFE_2895 peptidoglycan synthetase FtsI, putative K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D AFE_0212 ftsI; peptidoglycan synthetase FtsI K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D AFE_0213 ftsL; cell division protein FtsL K03586 ftsL; cell division protein FtsL
D AFE_0202 cell division protein FtsQ K03589 ftsQ; cell division protein FtsQ
D AFE_0207 ftsW; cell division protein FtsW K03588 ftsW; cell division protein FtsW
D AFE_2751 cell division protein FtsX, putative K09811 ftsX; cell division transport system permease protein
D AFE_0200 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D AFE_2142 conserved hypothetical protein K09888 zapA; cell division protein ZapA
D AFE_0188 conserved hypothetical protein K18778 zapD; cell division protein ZapD
D AFE_2361 N-acetylmuramoyl-L-alanine amidase, putative K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D AFE_0109 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system
D AFE_1879 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system
D AFE_0013 minC; septum site-determining protein MinC K03610 minC; septum site-determining protein MinC
D AFE_0012 minD; septum site-determining protein MinD K03609 minD; septum site-determining protein MinD
D AFE_0011 minE; cell division topological specificity factor MinE K03608 minE; cell division topological specificity factor
D AFE_1869 cell division inhibitor, putative K13053 sulA; cell division inhibitor SulA
D AFE_2562 mreB; rod shape-determining protein MreB K03569 mreB; rod shape-determining protein MreB and related proteins
D AFE_2563 mreC; rod shape-determining protein MreC K03570 mreC; rod shape-determining protein MreC
D AFE_2564 rod shape-determining protein MreD, putative K03571 mreD; rod shape-determining protein MreD
D AFE_2566 rodA; rod shape-determining protein RodA K05837 rodA; rod shape determining protein RodA
D AFE_1720 parA family protein K03496 parA; chromosome partitioning protein
D AFE_1680 conserved hypothetical protein K03496 parA; chromosome partitioning protein
D AFE_3212 chromosome partitioning protein parA K03496 parA; chromosome partitioning protein
D AFE_1875 ParA-like protein K03496 parA; chromosome partitioning protein
D AFE_3211 parB family protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D AFE_1719 parB family protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D AFE_2028 parC; DNA topoisomerase IV, A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D AFE_2029 parE; DNA topoisomerase IV, subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D AFE_3214 gidA; glucose-inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D AFE_3213 gidB; methyltransferase GidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D AFE_2746 xerC; tyrosine recombinase XerC K03733 xerC; integrase/recombinase XerC
D AFE_1145 tyrosine recombinase, phage integrase family K03733 xerC; integrase/recombinase XerC
D AFE_2850 xerD; tyrosine recombinase XerD K04763 xerD; integrase/recombinase XerD
D AFE_0834 site-specific recombinase, phage integrase family K04763 xerD; integrase/recombinase XerD
D AFE_0508 site-specific recombinase, phage integrase family K04763 xerD; integrase/recombinase XerD
D AFE_2398 site-specific recombinase, phage integrase family K04763 xerD; integrase/recombinase XerD
D AFE_2661 mrp; Mrp protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D AFE_0092 fic family protein K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]
D AFE_3092 ysxC; ribosome biogenesis GTP-binding protein YsxC K03978 engB; GTP-binding protein
C 03400 DNA repair and recombination proteins [BR:afr03400]
D AFE_1553 ogt-2; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AFE_2798 ogt-1; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AFE_3015 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D AFE_2682 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AFE_0227 mutator mutT protein/thiamine-phosphate pyrophosphorylase family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AFE_0356 dut; deoxyuridine 5`-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D AFE_1217 uracil-DNA glycosylase, family 4 K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D AFE_2882 uracil-DNA glycosylase family 4 protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D AFE_1848 base excision repair protein, HhH-GPD family K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D AFE_2799 transcriptional regulator, Ada family/DNA-3-methyladenine glycosylase II K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D AFE_2758 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D AFE_0463 formamidopyrimidine-DNA glycosylase, putative K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D AFE_0174 xth-2; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D AFE_0178 xth-1; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D AFE_0476 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D AFE_0757 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D AFE_1230 DNA ligase, NAD-dependent, putative K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D AFE_3094 polI; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D AFE_2847 uvrA; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
D AFE_0845 uvrB; excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
D AFE_0853 uvrC; excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C
D AFE_3101 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D AFE_1137 ATP-dependent DNA helicase, UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D AFE_0320 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D AFE_0321 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D AFE_0354 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D AFE_0564 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D AFE_0369 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D AFE_1760 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D AFE_2338 MutS2 family protein K07456 mutS2; DNA mismatch repair protein MutS2
D AFE_0744 MutS domain V protein K07456 mutS2; DNA mismatch repair protein MutS2
D AFE_1927 mutL; mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D AFE_1980 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D AFE_1976 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D AFE_1767 exodeoxyribonuclease X, putative K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D AFE_1461 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D AFE_0001 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D AFE_2203 holC; DNA polymerase III, chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
D AFE_0457 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D AFE_1914 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D AFE_0400 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D AFE_1919 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D AFE_1569 ssb-2; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_2845 ssb-1; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_1260 ssb-3; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_1568 methyltransferase, putative K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D AFE_2932 recB; exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
D AFE_2931 recC; exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
D AFE_2933 recD; exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
D AFE_1047 helicase, RecD/TraA family K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
D AFE_0932 recA; recA protein K03553 recA; recombination protein RecA
D AFE_0061 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D AFE_0062 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AFE_0060 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AFE_0591 priA; primosomal protein N` K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D AFE_2817 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
D AFE_0002 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
D AFE_0568 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D AFE_3194 ATP-dependent DNA helicase RecG domain protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D AFE_0827 ATP-dependent DNA helicase, putative K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D AFE_1402 DNA repair protein RecO, putative K03584 recO; DNA repair protein RecO (recombination protein O)
D AFE_1921 recR; recombination protein RecR K06187 recR; recombination protein RecR
D AFE_0450 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D AFE_0894 gyrA; DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D AFE_0003 gyrB; DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D AFE_0015 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D AFE_1013 DNA topoisomerase I, putative K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D AFE_1241 DNA-binding protein HU family protein K03530 hupB; DNA-binding protein HU-beta
D AFE_1584 DNA-binding protein HU family protein K03530 hupB; DNA-binding protein HU-beta
D AFE_2471 DNA-binding protein HU family protein K03530 hupB; DNA-binding protein HU-beta
D AFE_0914 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D AFE_0191 transcriptional regulator, Fis family K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
D AFE_1070 DNA-binding protein, HU family K04764 ihfA; integration host factor subunit alpha
D AFE_1583 integration host factor, alpha subunit, putative K04764 ihfA; integration host factor subunit alpha
D AFE_1586 DNA-binding protein, HU family K04764 ihfA; integration host factor subunit alpha
D AFE_2608 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
D AFE_0905 ihfB; integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
D AFE_2194 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D AFE_2654 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D AFE_1751 umuC protein K03502 umuC; DNA polymerase V
D AFE_1750 umuD; umuD protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D AFE_1868 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D AFE_1870 conserved hypothetical protein K14161 imuB; protein ImuB
D AFE_1871 DNA polymerase III, alpha subunit, putative K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D AFE_0933 recX; regulatory protein RecX K03565 recX; regulatory protein
D AFE_3104 DNA polymerase X family protein K02347 polX; DNA polymerase (family X)
D AFE_2187 rep; ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D AFE_2517 ATP-dependent helicase, DEXD family K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D AFE_2638 nrdA; ribonucleotide-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D AFE_2639 nrdB; ribonucleoside-diphosphate reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C 03029 Mitochondrial biogenesis [BR:afr03029]
D AFE_2730 petB-2; ubiquinol--cytochrome c reductase, cytochrome b subunit K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D AFE_3110 petB-1; ubiquinol--cytochrome c reductase, cytochrome b subunit K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D AFE_0391 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D AFE_2613 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D AFE_1445 tsf; translation elongation factor Ts K02357 tsf; elongation factor Ts
D AFE_0311 tuf-2; translation elongation factor Tu K02358 tuf; elongation factor Tu
D AFE_0325 tuf-1; translation elongation factor Tu K02358 tuf; elongation factor Tu
D AFE_0324 fusA; translation elongation factor G K02355 fusA; elongation factor G
D AFE_1401 era; GTP-binding protein Era K03595 era; GTPase
D AFE_3085 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D AFE_0459 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D AFE_0056 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D AFE_0170 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D AFE_2111 gatA; glutamyl-tRNA(Gln)/aspartyl-tRNA(Asn) amidotransferase, A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D AFE_2110 gatB; glutamyl-tRNA(Gln)/aspartyl-tRNA(Asn) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D AFE_2112 gatC; glutamyl-tRNA(Gln)/aspartyl-tRNA(Asn) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D AFE_1569 ssb-2; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_2845 ssb-1; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_1260 ssb-3; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D AFE_1452 outer membrane protein, OMP85 family K07277 SAM50; outer membrane protein insertion porin family
D AFE_2665 dnaK; chaperone protein Dnak K04043 dnaK; molecular chaperone DnaK
D AFE_2666 grpE; co-chaperone GrpE K03687 GRPE; molecular chaperone GrpE
D AFE_0542 groEL; chaperonin, 60 kDa K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D AFE_0543 groES; chaperonin, 10 kDa K04078 groES; chaperonin GroES
D AFE_2664 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D AFE_0956 metallo-beta-lactamase family protein K17725 ETHE1; sulfur dioxygenase [EC:1.13.11.18]
D AFE_1537 iscS-1; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D AFE_0673 iscS-3; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D AFE_1507 iscS-2; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D AFE_0676 hscB; co-chaperone Hsc20 K04082 hscB; molecular chaperone HscB
D AFE_3038 glutaredoxin-related protein K07390 grxD; monothiol glutaredoxin
D AFE_2661 mrp; Mrp protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D AFE_0635 cyoE-1; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D AFE_3143 cyoE-2; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D AFE_0032 inner membrane protein, 60 kDa K03217 yidC; YidC/Oxa1 family membrane protein insertase
D AFE_3158 htpG; heat shock protein HtpG K04079 HSP90A; molecular chaperone HtpG
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:afr02000]
D AFE_0983 ABC transporter, ATP-binding protein, MsbA family K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]
D AFE_2693 type I secretion system ATPase K11004 hlyB; ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
D AFE_2167 toxin secretion ABC transporter, ATP-binding protein, HlyB family K13409 cvaB; ATP-binding cassette, subfamily B, bacterial CvaB/MchF/RaxB
D AFE_2985 ABC transporter, permease/ATP-binding protein K18893 vcaM; ATP-binding cassette, subfamily B, multidrug efflux pump
D AFE_0617 ABC transporter, permease/ATP-binding protein K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial
D AFE_1390 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC K16012 cydC; ATP-binding cassette, subfamily C, bacterial CydC
D AFE_1388 cydD; ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD K16013 cydD; ATP-binding cassette, subfamily C, bacterial CydD
D AFE_0552 ABC transporter, permease/ATP-binding protein K02471 bacA; vitamin B12/bleomycin/antimicrobial peptide transport system ATP-binding/permease protein
D AFE_2893 ABC transporter, ATP-binding protein K15738 uup; ABC transport system ATP-binding/permease protein
D AFE_1493 molybdenum ABC transporter, periplasmic molybdate-binding protein, putative K02020 modA; molybdate transport system substrate-binding protein
D AFE_1498 ABC transporter, periplasmic substrate-binding protein, putative K15495 wtpA; molybdate/tungstate transport system substrate-binding protein
D AFE_2190 ABC transporter, permease protein K15496 wtpB; molybdate/tungstate transport system permease protein
D AFE_2189 ABC transporter, ATP-binding protein K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6]
D AFE_0250 membrane protein, putative K02069 STAR2; UDP-glucose/iron transport system permease protein
D AFE_2135 mce-related protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D AFE_0160 mce-related protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D AFE_0648 ABC transporter, permease protein, putative K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D AFE_0159 toluene tolerance protein Ttg2B, putative K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D AFE_0646 ABC transporter, ATP-binding protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D AFE_0158 toluene ABC transporter, ATP-binding protein, putative K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D AFE_2134 lipoprotein, putative K18480 linN; cholesterol transport system auxiliary component
D AFE_1830 toluene tolerance protein, putative K07323 mlaC; phospholipid transport system substrate-binding protein
D AFE_0161 toluene tolerance protein, putative K07323 mlaC; phospholipid transport system substrate-binding protein
D AFE_2114 conserved hypothetical protein K07323 mlaC; phospholipid transport system substrate-binding protein
D AFE_0162 conserved hypothetical protein K07122 mlaB; phospholipid transport system transporter-binding protein
D AFE_1436 pstS-2; phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D AFE_1939 pstS-1; phosphate ABC transporter, periplasmic phosphate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein
D AFE_1940 pstC_2; phosphate ABC transporter, permease protein PstC K02037 pstC; phosphate transport system permease protein
D AFE_1437 pstC-2; phosphate ABC transporter, permease protein PstC K02037 pstC; phosphate transport system permease protein
D AFE_1941 pstC_1; phosphate ABC transporter, permease protein, putative K02038 pstA; phosphate transport system permease protein
D AFE_1438 pstA; phosphate ABC transporter, permease protein PstA K02038 pstA; phosphate transport system permease protein
D AFE_1439 pstB; phosphate ABC transporter, ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D AFE_2987 peptide ABC transporter, periplasmic peptide-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D AFE_2992 peptide ABC transporter, periplasmic peptide-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D AFE_2991 peptide ABC transporter, permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein
D AFE_2990 peptide ABC transporter, permease protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D AFE_2989 peptide ABC transporter, ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D AFE_1489 iron compound ABC transporter, periplasmic iron-binding protein, putative K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D AFE_1494 iron compound ABC transporter, periplasmic iron-binding protein, putative K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D AFE_1490 ABC transporter, permease protein, FecCD family K02015 ABC.FEV.P; iron complex transport system permease protein
D AFE_1495 ABC transporter, permease protein, FecCD family K02015 ABC.FEV.P; iron complex transport system permease protein
D AFE_1491 iron compound ABC transporter, ATP-binding protein, putative K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D AFE_0602 cation ABC transporter, periplasmic cation-binding protein, putative K02077 ABC.ZM.S; zinc/manganese transport system substrate-binding protein
D AFE_0605 cation ABC transporter, permease protein, putative K02075 ABC.ZM.P; zinc/manganese transport system permease protein
D AFE_0604 cation ABC transporter, permease protein, putative K02075 ABC.ZM.P; zinc/manganese transport system permease protein
D AFE_0603 cation ABC transporter, ATP-binding protein, putative K02074 ABC.ZM.A; zinc/manganese transport system ATP-binding protein
D AFE_2962 ctrC; capsule polysaccharide exporter, inner-membrane protein CtrC K09688 kpsM; capsular polysaccharide transport system permease protein
D AFE_2961 capsule polysaccharide export inner-membrane protein K10107 kpsE; capsular polysaccharide transport system permease protein
D AFE_2963 ctrD; capsule polysaccharide exporter, ATP-binding protein K09689 kpsT; capsular polysaccharide transport system ATP-binding protein [EC:7.6.2.12]
D AFE_2200 YjgP/YjgQ family protein K07091 lptF; lipopolysaccharide export system permease protein
D AFE_2199 YjgP/YjgQ family protein K11720 lptG; lipopolysaccharide export system permease protein
D AFE_3026 ABC transporter, ATP-binding protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]
D AFE_3235 ABC-2 type transporter, permease protein, NodJ family K09694 nodJ; lipooligosaccharide transport system permease protein
D AFE_3236 ABC transporter, ATP-binding protein, NodI family K09695 nodI; lipooligosaccharide transport system ATP-binding protein
D AFE_2864 ABC transporter, permease protein, putative K25180 ybhR; drug efflux transport system permease protein
D AFE_1603 ABC transporter, permease protein, putative K25180 ybhR; drug efflux transport system permease protein
D AFE_2863 ABC transporter, permease protein, putative K25181 ybhS; drug efflux transport system permease protein
D AFE_1604 ABC transporter, permease protein, putative K25181 ybhS; drug efflux transport system permease protein
D AFE_1606 ABC transporter, ATP-binding protein K25182 ybhF; drug efflux transport system ATP-binding protein
D AFE_1605 ABC transporter, ATP-binding protein K25182 ybhF; drug efflux transport system ATP-binding protein
D AFE_2862 ABC transporter, ATP-binding protein K25182 ybhF; drug efflux transport system ATP-binding protein
D AFE_1607 secretion protein, HlyD family K25183 ybhG; membrane fusion protein YbhG
D AFE_2861 secretion protein, HlyD family K25183 ybhG; membrane fusion protein YbhG
D AFE_0481 lolC; lipoprotein releasing system transmembrane protein LolC K09808 lolC_E; lipoprotein-releasing system permease protein
D AFE_0483 lolD; lipoprotein releasing system, ATP-binding protein LolD K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D AFE_2751 cell division protein FtsX, putative K09811 ftsX; cell division transport system permease protein
D AFE_2752 ftsE; cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein
D AFE_2106 ABC transporter, permease protein, putative K01992 ABC-2.P; ABC-2 type transport system permease protein
D AFE_2107 ABC transporter, permease protein, putative K01992 ABC-2.P; ABC-2 type transport system permease protein
D AFE_2296 conserved domain protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D AFE_3036 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein
D AFE_2604 ABC transporter, ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D AFE_0163 ABC transporter, ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D AFE_2105 ABC transporter, ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D AFE_3164 ABC transporter, ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D AFE_0102 ABC transporter, permease protein, putative K02004 ABC.CD.P; putative ABC transport system permease protein
D AFE_0654 ABC transporter, permease protein K02004 ABC.CD.P; putative ABC transport system permease protein
D AFE_0655 ABC transporter, ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D AFE_0101 ABC transporter, ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D AFE_2312 sugar transporter family protein K08137 galP; MFS transporter, SP family, galactose:H+ symporter
D AFE_1971 transporter, putative K05820 hcaT; MFS transporter, PPP family, 3-phenylpropionic acid transporter
D AFE_1961 AmpG permease protein, putative K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG
D AFE_1797 drug resistance transporter, EmrB/QacA family K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein
D AFE_2091 drug resistance transporter, EmrB/QacA family K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein
D AFE_2184 drug resistance transporter, EmrB/QacA family K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein
D AFE_0864 drug resistance transporter, EmrB/QacA family K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein
D AFE_2349 multidrug resistance protein K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein
D AFE_0040 drug resistance transporter, EmrB/QacA family K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein
D AFE_0171 drug resistance transporter,putative, EmrB/QacA subfamily K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein
D AFE_1977 fosmidomycin resistance protein, putative K08223 fsr; MFS transporter, FSR family, fosmidomycin resistance protein
D AFE_2333 major facilitator family transporter K08224 ynfM; MFS transporter, YNFM family, putative membrane transport protein
D AFE_3296 major facilitator family transporter K08368 yaaU; MFS transporter, putative metabolite transport protein
D AFE_1809 major facilitator family protein K08368 yaaU; MFS transporter, putative metabolite transport protein
D AFE_2277 major facilitator family transporter K08368 yaaU; MFS transporter, putative metabolite transport protein
D AFE_3018 ptsI; phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D AFE_3019 ptsH; phosphocarrier protein HPr K02784 ptsH; phosphocarrier protein HPr
D AFE_3020 PTS system, IIA component, putative K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D AFE_3023 phosphoenolpyruvate-dependent sugar PTS system, EIIA component K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]
D AFE_0154 MIP family channel protein K06188 aqpZ; aquaporin Z
D AFE_2922 cation channel protein, putative K10716 kch; voltage-gated potassium channel
D AFE_3093 cation channel protein, putative K10716 kch; voltage-gated potassium channel
D AFE_2911 amt-2; ammonium transporter K03320 amt; ammonium transporter, Amt family
D AFE_2916 amt-1; ammonium transporter K03320 amt; ammonium transporter, Amt family
D AFE_1922 amtB; ammonium transporter family protein K03320 amt; ammonium transporter, Amt family
D AFE_2594 gst; glutathione S-transferase K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D AFE_1474 glutathione S-transferase, putative K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D AFE_0177 glutathione S-transferase family protein K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D AFE_0291 glutathione S-transferase family protein K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D AFE_0221 sspA; stringent starvation protein A K03599 sspA; stringent starvation protein A
D AFE_1764 membrane protein, putative K19416 yccA; modulator of FtsH protease
D AFE_3260 mscL; large conductance mechanosensitive channel protein K03282 mscL; large conductance mechanosensitive channel
D AFE_1784 mechanosensitive ion channel family protein K05802 mscK; potassium-dependent mechanosensitive channel
D AFE_3003 MotA/TolQ/ExbB proton channel family protein K03561 exbB; biopolymer transport protein ExbB
D AFE_0768 MotA/TolQ/ExbB proton channel family protein K03561 exbB; biopolymer transport protein ExbB
D AFE_2270 MotA/TolQ/ExbB proton channel family protein K03561 exbB; biopolymer transport protein ExbB
D AFE_2273 MotA/TolQ/ExbB proton channel family protein K03561 exbB; biopolymer transport protein ExbB
D AFE_2299 MotA/TolQ/ExbB proton channel family protein K03561 exbB; biopolymer transport protein ExbB
D AFE_0485 MotA/TolQ/ExbB proton channel family protein K03561 exbB; biopolymer transport protein ExbB
D AFE_1485 MotA/TolQ/ExbB proton channel family protein K03561 exbB; biopolymer transport protein ExbB
D AFE_3004 biopolymer transport protein, ExbD/TolR family K03559 exbD; biopolymer transport protein ExbD
D AFE_0769 biopolymer transport protein, ExbD/TolR family K03559 exbD; biopolymer transport protein ExbD
D AFE_2269 biopolymer transport protein, ExbD/TolR family K03559 exbD; biopolymer transport protein ExbD
D AFE_0486 biopolymer transport protein, ExbD/TolR family K03559 exbD; biopolymer transport protein ExbD
D AFE_1486 biopolymer transport protein, ExbD/TolR family K03559 exbD; biopolymer transport protein ExbD
D AFE_2300 biopolymer transport protein, ExbD/TolR family K03559 exbD; biopolymer transport protein ExbD
D AFE_0064 tolQ; TolQ protein K03562 tolQ; biopolymer transport protein TolQ
D AFE_0065 tolR; TolR protein K03560 tolR; biopolymer transport protein TolR
D AFE_3219 magnesium and cobalt transport protein, putative K03284 corA; magnesium transporter
D AFE_3218 magnesium and cobalt transport protein, putative K03284 corA; magnesium transporter
D AFE_3221 magnesium and cobalt transport protein, putative K03284 corA; magnesium transporter
D AFE_2926 crcB protein, putative K06199 crcB; fluoride exporter
D AFE_2480 merC; mercuric resistance protein MerC K19058 merC; mercuric ion transport protein
D AFE_2930 membrane protein, putative K24915 TMEM175; TMEM175 potassium channel family protein
D AFE_2061 CBS domain protein K03699 tlyC; magnesium and cobalt exporter, CNNM family
D AFE_0531 conserved domain protein K03286 TC.OOP; OmpA-OmpF porin, OOP family
D AFE_0306 OmpA family protein K03286 TC.OOP; OmpA-OmpF porin, OOP family
D AFE_0378 outer membrane protein transport protein, OMPP1/FadL/TodX family K06076 fadL; long-chain fatty acid transport protein
D AFE_2542 outer membrane protein, OMPP1/FadL/TodX family K06076 fadL; long-chain fatty acid transport protein
D AFE_0007 outer membrane usher protein, putative K07347 fimD; outer membrane usher protein
D AFE_2288 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D AFE_2292 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D AFE_1483 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D AFE_1492 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D AFE_2298 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D AFE_0763 TonB-dependent receptor, putative K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D AFE_1484 conserved hypothetical protein K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D AFE_2040 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D AFE_2302 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D AFE_3229 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D AFE_2935 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D AFE_2936 conserved hypothetical protein K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D AFE_1949 outer membrane heavy metal efflux protein, putative K15725 czcC; outer membrane protein, heavy metal efflux system
D AFE_2037 outer membrane efflux protein K15725 czcC; outer membrane protein, heavy metal efflux system
D AFE_2434 outer membrane efflux protein K15725 czcC; outer membrane protein, heavy metal efflux system
D AFE_0575 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein
D AFE_2045 outer membrane efflux protein K12340 tolC; outer membrane protein
D AFE_3265 outer membrane efflux protein K12340 tolC; outer membrane protein
D AFE_2169 outer membrane toxin secretion efflux protein, putative K12340 tolC; outer membrane protein
D AFE_2690 type I secretion outer membrane protein, putative K18139 oprM; outer membrane protein, multidrug efflux system
D AFE_0039 RND efflux system, drug efflux transporter, outer membrane lipoprotein K15550 mdtP; outer membrane protein, multidrug efflux system
D AFE_1339 polysaccharide biosynthesis/export domain protein K01991 wza; polysaccharide biosynthesis/export protein
D AFE_2975 capsule polysaccharide export protein, BexD/CtrA/VexA family K01991 wza; polysaccharide biosynthesis/export protein
D AFE_2250 carbohydrate-selective porin, OprB family K07267 oprB; porin
D AFE_2522 carbohydrate-selective porin, OprB family K07267 oprB; porin
D AFE_1452 outer membrane protein, OMP85 family K07277 SAM50; outer membrane protein insertion porin family
D AFE_1936 PQQ enzyme repeat domain protein K17713 bamB; outer membrane protein assembly factor BamB
D AFE_0430 competence lipoprotein ComL, putative K05807 bamD; outer membrane protein assembly factor BamD
D AFE_0279 lipoprotein, SmpA/OmlA family K06186 bamE; outer membrane protein assembly factor BamE
D AFE_1958 outer membrane protein, OMP85 family K07278 tamA; translocation and assembly module TamA
D AFE_1957 conserved hypothetical protein K09800 tamB; translocation and assembly module TamB
D AFE_2684 hemagluttinin family protein K21449 ata; trimeric autotransporter adhesin
D AFE_3027 conserved hypothetical protein K09774 lptA; lipopolysaccharide export system protein LptA
D AFE_3028 hypothetical protein K11719 lptC; lipopolysaccharide export system protein LptC
D AFE_3034 organic solvent tolerance protein, putative K04744 lptD; LPS-assembly protein
D AFE_0458 rare lipoprotein B, putative K03643 lptE; LPS-assembly lipoprotein
D AFE_0599 magnesium and cobalt efflux protein, putative K06189 corC; hemolysin (HlyC) family protein
D AFE_1685 cscC; carboxysome shell peptide K04027 eutM; ethanolamine utilization protein EutM
D AFE_2420 cation diffusion facilitator family transporter K16264 czcD; cobalt-zinc-cadmium efflux system protein
D AFE_1430 cation diffusion facilitator family transporter K16264 czcD; cobalt-zinc-cadmium efflux system protein
D AFE_2431 heavy metal efflux pump, CzcA family K07787 cusA; copper/silver efflux system protein
D AFE_1947 heavy metal efflux pump, CzcA family K07787 cusA; copper/silver efflux system protein
D AFE_1878 transporter, AcrB/AcrD/AcrF family K18138 acrB; multidrug efflux pump
D AFE_2802 multidrug resistance protein, SMR family K03297 emrE; small multidrug resistance pump
D AFE_0587 sodium/calcium exchanger K07301 yrbG; cation:H+ antiporter
D AFE_2205 nhaA; Na+/H+ antiporter NhaA K03313 nhaA; Na+:H+ antiporter, NhaA family
D AFE_2245 Na+/H+ antiporter, putative K03316 nhaP; Na+:H+ antiporter
D AFE_2454 Na+/H+ antiporter K03316 nhaP; Na+:H+ antiporter
D AFE_1968 potassium-efflux system protein K03455 KEA1_2_3; K+:H+ antiporter
D AFE_0791 Na+/H+ antiporter, putative K26731 CHX; K+:H+ antiporter
D AFE_0815 voltage-gated chloride channel K03281 clcA; chloride channel protein, CIC family
D AFE_3129 voltage-gated chloride channel K03281 clcA; chloride channel protein, CIC family
D AFE_0814 voltage-gated chloride channel K03281 clcA; chloride channel protein, CIC family
D AFE_2858 arsB; arsenical pump membrane protein K03893 arsB; arsenical pump membrane protein
D AFE_0559 mviN; integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase
D AFE_1753 kup; potassium uptake protein K03549 kup; KUP system potassium uptake protein
D AFE_0153 integral membrane protein K22736 VIT; vacuolar iron transporter family protein
D AFE_0054 integral membrane protein, MarC family K05595 marC; multiple antibiotic resistance protein
D AFE_2999 integral membrane protein, MarC family K05595 marC; multiple antibiotic resistance protein
D AFE_0207 ftsW; cell division protein FtsW K03588 ftsW; cell division protein FtsW
D AFE_3002 TonB family protein K03832 tonB; periplasmic protein TonB
D AFE_2268 TonB family protein K03832 tonB; periplasmic protein TonB
D AFE_2275 TonB family protein K03832 tonB; periplasmic protein TonB
D AFE_2301 TonB family protein K03832 tonB; periplasmic protein TonB
D AFE_2304 TonB family protein K03832 tonB; periplasmic protein TonB
D AFE_1487 TonB family protein K03832 tonB; periplasmic protein TonB
D AFE_1978 TonB family protein K03832 tonB; periplasmic protein TonB
D AFE_0770 TonB family protein K03832 tonB; periplasmic protein TonB
D AFE_2689 TonB family protein K03832 tonB; periplasmic protein TonB
D AFE_0071 peptidoglycan-associated lipoprotein, putative K03640 pal; peptidoglycan-associated lipoprotein
D AFE_0066 tolA; TolA protein K03646 tolA; colicin import membrane protein
D AFE_0067 tolB; tol-pal system beta propeller repeat protein TolB K03641 tolB; TolB protein
D AFE_0862 drug resistance transporter, putative K03543 emrA; membrane fusion protein, multidrug efflux system
D AFE_0257 secretion protein, HlyD family K03543 emrA; membrane fusion protein, multidrug efflux system
D AFE_0038 drug resistance secretion protein, putative K03543 emrA; membrane fusion protein, multidrug efflux system
D AFE_1948 heavy metal efflux transporter, MFP subunit, putative K07798 cusB; membrane fusion protein, copper/silver efflux system
D AFE_2433 efflux transporter, RND family, MFP subunit K07798 cusB; membrane fusion protein, copper/silver efflux system
D AFE_2692 type I secretion membrane fusion protein, HlyD family K11003 hlyD; membrane fusion protein, hemolysin D
D AFE_2166 toxin secretion protein, HlyD family K13408 cvaA; membrane fusion protein
D AFE_2367 efflux transporter, RND family, MFP subunit K18302 mexJ; membrane fusion protein, multidrug efflux system
D AFE_2103 efflux transporter, RND family, MFP subunit K21135 mexM; membrane fusion protein, multidrug efflux system
D AFE_0109 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system
D AFE_1879 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system
D AFE_3264 efflux transporter, RND family, MFP subunit K07799 mdtA; membrane fusion protein, multidrug efflux system
D AFE_1340 tyrosine-protein kinase, putative K16692 etk-wzc; tyrosine-protein kinase Etk/Wzc [EC:2.7.10.3]
D AFE_2523 feoA family protein K04758 feoA; ferrous iron transport protein A
D AFE_2524 feoB; ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B
D AFE_2651 copper resistance protein, putative K07245 pcoD; copper resistance protein D
C 02044 Secretion system [BR:afr02044]
D AFE_2693 type I secretion system ATPase K11004 hlyB; ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
D AFE_2692 type I secretion membrane fusion protein, HlyD family K11003 hlyD; membrane fusion protein, hemolysin D
D AFE_0575 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein
D AFE_2045 outer membrane efflux protein K12340 tolC; outer membrane protein
D AFE_3265 outer membrane efflux protein K12340 tolC; outer membrane protein
D AFE_2169 outer membrane toxin secretion efflux protein, putative K12340 tolC; outer membrane protein
D AFE_2166 toxin secretion protein, HlyD family K13408 cvaA; membrane fusion protein
D AFE_2167 toxin secretion ABC transporter, ATP-binding protein, HlyB family K13409 cvaB; ATP-binding cassette, subfamily B, bacterial CvaB/MchF/RaxB
D AFE_0837 general secretion pathway protein A, putative K02450 gspA; general secretion pathway protein A
D AFE_0186 pilD; type IV pilus prepilin peptidase PilD K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
D AFE_0416 pilin, putative K02650 pilA; type IV pilus assembly protein PilA
D AFE_0183 type IV pilus assembly protein K02652 pilB; type IV pilus assembly protein PilB
D AFE_0972 pilC; type IV pilus biogenesis protein PilC K02653 pilC; type IV pilus assembly protein PilC
D AFE_1931 pilF; type IV pilus biogenesis/stability protein PilW K02656 pilF; type IV pilus assembly protein PilF
D AFE_0739 type IV pilus assembly protein PilM K02662 pilM; type IV pilus assembly protein PilM
D AFE_0738 type IV pilus biogenesis protein PilN K02663 pilN; type IV pilus assembly protein PilN
D AFE_0737 fimbrial assembly protein PilO, putative K02664 pilO; type IV pilus assembly protein PilO
D AFE_0736 type 4 fimbrial biogenesis protein PilP, putative K02665 pilP; type IV pilus assembly protein PilP
D AFE_0735 fimbrial assembly protein PilQ, putative K02666 pilQ; type IV pilus assembly protein PilQ
D AFE_0264 pilT-2; twitching motility protein PilT K02669 pilT; twitching motility protein PilT
D AFE_0265 pilT-1; twitching motility protein PilT K02670 pilU; twitching motility protein PilU
D AFE_0969 type IV pilin, putative K02672 pilW; type IV pilus assembly protein PilW
D AFE_0967 type IV pilin biogenesis protein, putative K02674 pilY1; type IV pilus assembly protein PilY1
D AFE_1915 type IV pilus assembly protein PilZ, putative K02676 pilZ; type IV pilus assembly protein PilZ
D AFE_0971 pilin signal sequence domain protein K08084 fimT; type IV fimbrial biogenesis protein FimT
D AFE_2072 conserved domain protein K08086 fimV; pilus assembly protein FimV
D AFE_2708 membrane protein, putative K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
D AFE_2705 conserved hypothetical protein K02279 cpaB; pilus assembly protein CpaB
D AFE_2704 bacterial type II/III secretion system protein K02280 cpaC; pilus assembly protein CpaC
D AFE_2703 pilus assembly protein CpaE, putative K02282 cpaE; pilus assembly protein CpaE
D AFE_2702 tadA; tight adherence protein TadA K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D AFE_2701 tadB; tight adherence protein TadB, putative K12510 tadB; tight adherence protein B
D AFE_2700 tadC; tight adherence protein TadC K12511 tadC; tight adherence protein C
D AFE_2699 lipoprotein, putative K27079 tadD; tight adherence protein D
D AFE_2697 conserved hypothetical protein K27080 tadG; tight adherence protein G
D AFE_2710 pilin, putative K02651 flp; pilus assembly protein Flp/PilA
D AFE_1087 type II/IV secretion system protein K12276 mshE; MSHA biogenesis protein MshE
D AFE_0261 YGGT family protein K02221 yggT; YggT family protein
D AFE_3100 competence protein ComEA helix-hairpin-helix repeat protein K02237 comEA; competence protein ComEA
D AFE_3301 competence protein ComEA helix-hairpin-helix repeat protein K02237 comEA; competence protein ComEA
D AFE_0484 DNA internalization-related competence protein ComEC/Rec2 K02238 comEC; competence protein ComEC
D AFE_1698 conjugal transfer -like protein K03194 virB1; type IV secretion system protein VirB1
D AFE_1699 TraG/TraD family protein K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8]
D AFE_1068 pilus assembly protein TraG, putative K12056 traG; conjugal transfer mating pair stabilization protein TraG
D AFE_1066 pilus assembly protein TraF, putative K12057 traF; conjugal transfer pilus assembly protein TraF
D AFE_1096 conjugal transfer protein TraU, putative K12060 traU; conjugal transfer pilus assembly protein TraU
D AFE_1095 pilus assembly protein TraW, putative K12061 traW; conjugal transfer pilus assembly protein TraW
D AFE_1091 conjugation signal peptidase TraF, putative K12062 trbI; conjugal transfer pilin signal peptidase TrbI
D AFE_1089 traC; type-IV secretion system protein TraC K12063 traC; conjugal transfer ATP-binding protein TraC
D AFE_1082 traV; conjugal transfer protein TraV, putative K12064 traV; conjugal transfer pilus assembly protein TraV
D AFE_1081 conjugal transfer protein, putative K12065 traB; conjugal transfer pilus assembly protein TraB
D AFE_1080 traK; TraK lipoprotein, putative K12066 traK; conjugal transfer pilus assembly protein TraK
D AFE_1079 traE; type IV conjugative transfer system protein TraE K12067 traE; conjugal transfer pilus assembly protein TraE
D AFE_1078 traL; type IV conjugative transfer system protein TraL K12068 traL; conjugal transfer pilus assembly protein TraL
D AFE_1084 traA; conjugal transfer protein TraA, putative K12069 traA; conjugal transfer pilus assembly protein TraA
D AFE_1067 pilus assembly protein TraH, putative K12072 traH; conjugative transfer pilus assembly protein TraH
D AFE_1634 trbB; P-type conjugative transfer protein TrbB K20527 trbB; type IV secretion system protein TrbB [EC:7.4.2.8]
D AFE_1637 conjugal transfer protein TrbD, putative K20529 trbD; type IV secretion system protein TrbD
D AFE_1638 conjugal transfer protein trbE, putative K20530 trbE; type IV secretion system protein TrbE [EC:7.4.2.8]
D AFE_1694 conjugal transfer protein K20531 trbF; type IV secretion system protein TrbF
D AFE_1696 conjugal transfer protein, putative K20532 trbG; type IV secretion system protein TrbG
D AFE_1695 conjugal transfer protein K20532 trbG; type IV secretion system protein TrbG
D AFE_1640 conjugal transfer protein trbJ, putative K20266 trbJ; type IV secretion system protein TrbJ
D AFE_1642 conjugal transfer protein trbL, putative K07344 trbL; type IV secretion system protein TrbL
D AFE_0006 pilus chaperone protein, putative K07346 fimC; fimbrial chaperone protein
D AFE_0007 outer membrane usher protein, putative K07347 fimD; outer membrane usher protein
D AFE_0005 spore coat protein K27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1/2/3/6
D AFE_0008 spore coat protein K27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1/2/3/6
D AFE_0225 secA; preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D AFE_2127 secB; preprotein translocase, SecB subunit K03071 secB; preprotein translocase subunit SecB
D AFE_2057 secD; protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD
D AFE_0313 secE; preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE
D AFE_2056 secF; protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D AFE_2632 secG; preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG
D AFE_0347 secY; preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D AFE_2856 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D AFE_2753 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D AFE_2058 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D AFE_0032 inner membrane protein, 60 kDa K03217 yidC; YidC/Oxa1 family membrane protein insertase
D AFE_3131 twin-arginine translocation protein, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D AFE_3048 tatA; twin-arginine translocation protein, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D AFE_3049 tatB; twin-arginine translocation protein TatB K03117 tatB; sec-independent protein translocase protein TatB
D AFE_3050 tatC; Sec-independent protein translocase TatC K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins [BR:afr02042]
D AFE_2061 CBS domain protein K03699 tlyC; magnesium and cobalt exporter, CNNM family
D AFE_2360 channel protein, hemolysin III family K11068 hlyIII; hemolysin III
C 02022 Two-component system [BR:afr02022]
D AFE_1435 phoR; phosphate regulon sensor protein PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
D AFE_2934 transcriptional regulator, putative K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
D AFE_1434 phoB; DNA-binding response regulator PhoB K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
D AFE_2306 DNA-binding response regulator K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
D AFE_2271 transcriptional regulator, putative K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
D AFE_3275 osmolarity sensor protein EnvZ, putative K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
D AFE_0106 sensor histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
D AFE_2318 sensor histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
D AFE_0107 DNA-binding response regulator K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
D AFE_3274 transcriptional regulator OmpR, putative K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
D AFE_2319 DNA-binding response regulator K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
D AFE_2229 kdpD; sensor histidine kinase KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
D AFE_2228 kdpE; DNA-binding response regulator KdpE K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
D AFE_2031 sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D AFE_2032 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
D AFE_2902 ntrB; nitrogen regulation protein NR(II) K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
D AFE_2901 ntrC; nitrogen regulation protein NR(I) K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
D AFE_0023 ntrY; nitrogen regulation protein NtrY, putative K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
D AFE_0024 ntrX; nitrogen assimilation regulatory protein NtrX, putative K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
D AFE_0026 sensor histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
D AFE_0027 sigma-54 dependent transcriptional regulator/response regulator K07714 atoC; two-component system, NtrC family, response regulator AtoC
D AFE_0184 sensor protein PilS, putative K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
D AFE_0185 type IV fimbriae expression regulatory protein PilR, putative K02667 pilR; two-component system, NtrC family, response regulator PilR
D AFE_2957 sensor histidine kinase K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
D AFE_0449 sensor histidine kinase K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
D AFE_2955 sigma-54 dependent DNA-binding response regulator, putative K07715 glrR; two-component system, NtrC family, response regulator GlrR
D AFE_0447 sigma-54 dependent DNA-binding response regulator K07715 glrR; two-component system, NtrC family, response regulator GlrR
D AFE_0700 hupR; hydrogenase sigma-54 dependent DNA-binding response regulator K19641 hupR; two-component system, NtrC family, response regulator HupR/HoxA
D AFE_3136 sensor histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
D AFE_3137 DNA-binding response regulator K15012 regA; two-component system, response regulator RegA
C 02035 Bacterial motility proteins [BR:afr02035]
D AFE_0185 type IV fimbriae expression regulatory protein PilR, putative K02667 pilR; two-component system, NtrC family, response regulator PilR
D AFE_0184 sensor protein PilS, putative K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
D AFE_0264 pilT-2; twitching motility protein PilT K02669 pilT; twitching motility protein PilT
D AFE_0265 pilT-1; twitching motility protein PilT K02670 pilU; twitching motility protein PilU
D AFE_0416 pilin, putative K02650 pilA; type IV pilus assembly protein PilA
D AFE_0183 type IV pilus assembly protein K02652 pilB; type IV pilus assembly protein PilB
D AFE_0972 pilC; type IV pilus biogenesis protein PilC K02653 pilC; type IV pilus assembly protein PilC
D AFE_0186 pilD; type IV pilus prepilin peptidase PilD K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
D AFE_1931 pilF; type IV pilus biogenesis/stability protein PilW K02656 pilF; type IV pilus assembly protein PilF
D AFE_0735 fimbrial assembly protein PilQ, putative K02666 pilQ; type IV pilus assembly protein PilQ
D AFE_0736 type 4 fimbrial biogenesis protein PilP, putative K02665 pilP; type IV pilus assembly protein PilP
D AFE_0737 fimbrial assembly protein PilO, putative K02664 pilO; type IV pilus assembly protein PilO
D AFE_0738 type IV pilus biogenesis protein PilN K02663 pilN; type IV pilus assembly protein PilN
D AFE_0739 type IV pilus assembly protein PilM K02662 pilM; type IV pilus assembly protein PilM
D AFE_1915 type IV pilus assembly protein PilZ, putative K02676 pilZ; type IV pilus assembly protein PilZ
D AFE_0969 type IV pilin, putative K02672 pilW; type IV pilus assembly protein PilW
D AFE_0967 type IV pilin biogenesis protein, putative K02674 pilY1; type IV pilus assembly protein PilY1
D AFE_2710 pilin, putative K02651 flp; pilus assembly protein Flp/PilA
D AFE_2708 membrane protein, putative K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
D AFE_2705 conserved hypothetical protein K02279 cpaB; pilus assembly protein CpaB
D AFE_2704 bacterial type II/III secretion system protein K02280 cpaC; pilus assembly protein CpaC
D AFE_2703 pilus assembly protein CpaE, putative K02282 cpaE; pilus assembly protein CpaE
D AFE_2702 tadA; tight adherence protein TadA K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D AFE_0006 pilus chaperone protein, putative K07346 fimC; fimbrial chaperone protein
D AFE_0007 outer membrane usher protein, putative K07347 fimD; outer membrane usher protein
D AFE_0005 spore coat protein K27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1/2/3/6
D AFE_0008 spore coat protein K27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1/2/3/6
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:afr04812]
D AFE_0572 conserved hypothetical protein K06990 MEMO1; MEMO1 family protein
D AFE_2562 mreB; rod shape-determining protein MreB K03569 mreB; rod shape-determining protein MreB and related proteins
D AFE_0200 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D AFE_0201 ftsA; cell division protein FtsA K03590 ftsA; cell division protein FtsA
D AFE_0013 minC; septum site-determining protein MinC K03610 minC; septum site-determining protein MinC
D AFE_0012 minD; septum site-determining protein MinD K03609 minD; septum site-determining protein MinD
D AFE_0011 minE; cell division topological specificity factor MinE K03608 minE; cell division topological specificity factor
D AFE_1720 parA family protein K03496 parA; chromosome partitioning protein
D AFE_1680 conserved hypothetical protein K03496 parA; chromosome partitioning protein
D AFE_3212 chromosome partitioning protein parA K03496 parA; chromosome partitioning protein
D AFE_1875 ParA-like protein K03496 parA; chromosome partitioning protein
D AFE_3211 parB family protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D AFE_1719 parB family protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
C 04147 Exosome [BR:afr04147]
D AFE_3158 htpG; heat shock protein HtpG K04079 HSP90A; molecular chaperone HtpG
D AFE_0849 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D AFE_3251 gap; glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D AFE_3250 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D AFE_0749 pyruvate kinase barrel domain protein K00873 PK; pyruvate kinase [EC:2.7.1.40]
D AFE_1801 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D AFE_3249 pykA; pyruvate kinase II K00873 PK; pyruvate kinase [EC:2.7.1.40]
D AFE_0985 antioxidant, AhpC/Tsa family K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D AFE_0542 groEL; chaperonin, 60 kDa K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D AFE_2665 dnaK; chaperone protein Dnak K04043 dnaK; molecular chaperone DnaK
D AFE_2924 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D AFE_1777 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D AFE_0311 tuf-2; translation elongation factor Tu K02358 tuf; elongation factor Tu
D AFE_0325 tuf-1; translation elongation factor Tu K02358 tuf; elongation factor Tu
D AFE_3302 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D AFE_0220 AMP-binding protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D AFE_0534 ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D AFE_0348 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D AFE_0540 adenine phosphoribosyltransferase, putative K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D AFE_3277 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D AFE_0404 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D AFE_0189 fbp; fructose-1-6-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D AFE_2836 glgB; 1,4-alpha-glucan branching enzyme K00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]
D AFE_0466 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D AFE_3298 hemB; delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D AFE_1861 phhB; pterin-4-alpha-carbinolamine dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D AFE_0896 serA; D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D AFE_2260 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D AFE_1893 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_3068 pdhC; pyruvate dehydrogenase complex, E2 and E3 components K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_0958 pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D AFE_1479 fixB; electron transfer flavoprotein, alpha subunit K03522 fixB; electron transfer flavoprotein alpha subunit
D AFE_2025 zwf; glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D AFE_2633 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 02048 Prokaryotic defense system [BR:afr02048]
D AFE_0683 type I restriction-modification system, R subunit K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D AFE_2381 type I restriction-modification system, R subunit K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D AFE_0841 type I restriction-modification system, R subunit K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D AFE_2790 type I restriction-modification enzyme, R subunit K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D AFE_1575 type I restriction-modification system, R subunit K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D AFE_2378 type I restriction-modification system, S subunit K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D AFE_0829 type I restriction-modification system, S subunit K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D AFE_2791 type I restriction-modification system, S subunit K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D AFE_1576 type I restriction-modification system, S subunit K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D AFE_0686 type I restriction-modification system, S subunit, putative K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D AFE_0684 type I restriction-modification system, M subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D AFE_2372 type I restriction-modification system, M subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D AFE_0826 type I restriction-modification system, M subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D AFE_2793 type I restriction-modification system, M subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D AFE_1577 type I restriction-modification system, M subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D AFE_1568 methyltransferase, putative K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D AFE_3192 type III restriction-modification system, Mod subunit K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]
D AFE_3191 type III restriction-modification system, Res subunit K01156 res; type III restriction enzyme [EC:3.1.21.5]
D AFE_3186 mrr; Mrr restriction system protein K07448 mrr; restriction system protein
D AFE_2769 restriction endonuclease, putative K07448 mrr; restriction system protein
D AFE_2885 PemK family protein K07171 mazF; mRNA interferase MazF [EC:3.1.-.-]
D AFE_1099 chpA; ChpA protein K07171 mazF; mRNA interferase MazF [EC:3.1.-.-]
D AFE_2886 PemI family protein K07172 mazE; antitoxin MazE
D AFE_2889 transcriptional regulator, AbrB family K07172 mazE; antitoxin MazE
D AFE_1098 pemI family protein K07172 mazE; antitoxin MazE
D AFE_1412 conserved hypothetical protein K19155 yhaV; toxin YhaV [EC:3.1.-.-]
D AFE_1413 sohA; htrA suppressor protein K19156 prlF; antitoxin PrlF
D AFE_0890 stability protein StbE, putative K06218 relE; mRNA interferase RelE/StbE
D AFE_0889 stability protein StbD, putative K18923 stbD; antitoxin StbD
D AFE_1589 dinJ; DNA-damage-inducible protein J K07473 dinJ; DNA-damage-inducible protein J
D AFE_0412 addiction module toxin, Txe/YoeB family K19158 yoeB; toxin YoeB [EC:3.1.-.-]
D AFE_0870 addiction module toxin, Txe/YoeB family K19158 yoeB; toxin YoeB [EC:3.1.-.-]
D AFE_0869 addiction module antitoxin, Axe family K19159 yefM; antitoxin YefM
D AFE_1733 conserved hypothetical protein K18843 hicB; antitoxin HicB
D AFE_2982 conserved hypothetical protein K19092 parE1_3_4; toxin ParE1/3/4
D AFE_0088 plasmid maintenance system killer protein K07334 higB-1; toxin HigB-1
D AFE_0089 DNA-binding protein, putative K21498 higA-1; antitoxin HigA-1
D AFE_1754 virulence-associated protein, putative K21498 higA-1; antitoxin HigA-1
D AFE_2655 PIN domain protein K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D AFE_2129 virulence-associated protein, putative K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D AFE_0478 virulence-associated protein, putative K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D AFE_0477 virulence protein, putative K18829 mvpT; antitoxin VapB
D AFE_2771 SpoVT/AbrB like domain protein K18829 mvpT; antitoxin VapB
D AFE_2130 virulence-associated protein, putative K18829 mvpT; antitoxin VapB
D AFE_1780 plasmid stability protein, putative K07062 fitB; toxin FitB [EC:3.1.-.-]
D AFE_1362 plasmid stability protein, putative K07062 fitB; toxin FitB [EC:3.1.-.-]
D AFE_1361 plasmid stability protein, putative K21495 fitA; antitoxin FitA
D AFE_1779 plasmid stability protein, putative K21495 fitA; antitoxin FitA
D AFE_0200 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D AFE_2562 mreB; rod shape-determining protein MreB K03569 mreB; rod shape-determining protein MreB and related proteins
D AFE_2028 parC; DNA topoisomerase IV, A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D AFE_2029 parE; DNA topoisomerase IV, subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D AFE_0422 gltX-2; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D AFE_1537 iscS-1; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D AFE_0673 iscS-3; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D AFE_1507 iscS-2; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels [BR:afr04040]
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules [BR:afr04090]
C 01504 Antimicrobial resistance genes [BR:afr01504]
D AFE_0462 d-alanyl-d-alanine dipeptidase, putative K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
D AFE_0109 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system
D AFE_1879 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system
D AFE_1878 transporter, AcrB/AcrD/AcrF family K18138 acrB; multidrug efflux pump
D AFE_2690 type I secretion outer membrane protein, putative K18139 oprM; outer membrane protein, multidrug efflux system
D AFE_2367 efflux transporter, RND family, MFP subunit K18302 mexJ; membrane fusion protein, multidrug efflux system
D AFE_0373 transcriptional regulator, MerR family K19591 cueR; MerR family transcriptional regulator, copper efflux regulator
D AFE_0575 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein
D AFE_2045 outer membrane efflux protein K12340 tolC; outer membrane protein
D AFE_3265 outer membrane efflux protein K12340 tolC; outer membrane protein
D AFE_2169 outer membrane toxin secretion efflux protein, putative K12340 tolC; outer membrane protein
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:afr03100]
D AFE_0994 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D AFE_1191 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D AFE_0386 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D AFE_3082 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D AFE_2353 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D AFE_0844 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D AFE_1156 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D AFE_1155 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D AFE_0586 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D AFE_2735 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D AFE_2016 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D AFE_1165 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D AFE_1829 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D AFE_1190 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D AFE_1179 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D AFE_0916 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D AFE_1172 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D AFE_0856 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D AFE_1161 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D AFE_2742 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D AFE_2765 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D AFE_1173 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D AFE_2359 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D AFE_2128 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D AFE_1163 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D AFE_1164 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D AFE_0309 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D AFE_1192 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D AFE_0855 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D AFE_2370 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D AFE_2767 tRNA-His K14226 tRNA-His; tRNA His
D AFE_1180 tRNA-His K14226 tRNA-His; tRNA His
D AFE_0385 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D AFE_3083 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D AFE_1166 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D AFE_1159 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_2315 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_1162 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_1157 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_1946 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_1890 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_2213 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_1187 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_2631 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D AFE_1160 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D AFE_1954 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D AFE_1182 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D AFE_0084 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D AFE_2335 tRNA-Met K14230 tRNA-Met; tRNA Met
D AFE_1171 tRNA-Met K14230 tRNA-Met; tRNA Met
D AFE_3233 tRNA-Met K14230 tRNA-Met; tRNA Met
D AFE_0383 tRNA-Met K14230 tRNA-Met; tRNA Met
D AFE_1168 tRNA-Met K14230 tRNA-Met; tRNA Met
D AFE_0145 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D AFE_1158 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D AFE_2326 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D AFE_2606 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D AFE_2898 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D AFE_1183 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D AFE_1189 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D AFE_0656 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D AFE_1185 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D AFE_2055 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D AFE_1181 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D AFE_1186 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D AFE_1188 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D AFE_1916 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D AFE_1193 pseudogene K14233 tRNA-Ser; tRNA Ser
D AFE_1177 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D AFE_0310 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D AFE_0891 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D AFE_1175 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D AFE_0578 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D AFE_0312 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D AFE_1194 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D AFE_0308 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D AFE_1184 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D AFE_0915 tRNA-Val K14237 tRNA-Val; tRNA Val
D AFE_2615 tRNA-Val K14237 tRNA-Val; tRNA Val
D AFE_1555 tRNA-Val K14237 tRNA-Val; tRNA Val
D AFE_1167 tRNA-Val K14237 tRNA-Val; tRNA Val
D AFE_0384 rrsB; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D AFE_3084 rrsA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D AFE_0387 rrlB; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D AFE_3081 rrlA; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D AFE_0388 rrfB; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D AFE_3080 rrfA; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D AFE_1918 sRNA K01983 ffs; SRP RNA
D AFE_1917 srpB; Bacterial signal recognition particle RNA K01983 ffs; SRP RNA
D AFE_0216 sRNA K01978 rnpB; M1 RNA
D AFE_0217 Bacterial RNase P class A K01978 rnpB; M1 RNA
D AFE_1411 AftmRNA K15035 ssrA; transfer-messenger RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D AFE_2122 conserved hypothetical protein K00091 E1.1.1.219; dihydroflavonol-4-reductase [EC:1.1.1.219]
D AFE_0951 aldehyde dehydrogenase (NAD) family protein K00154 E1.2.1.68; coniferyl-aldehyde dehydrogenase [EC:1.2.1.68]
D AFE_0776 xanthine dehydrogenase, iron-sulfur binding subunit, putative K03518 coxS; aerobic carbon-monoxide dehydrogenase small subunit [EC:1.2.5.3]
D AFE_1478 fixC; fixC protein K00313 fixC; electron transfer flavoprotein-quinone oxidoreductase [EC:1.5.5.-]
D AFE_2946 msrA; peptide-methionine (S)-S-oxide reductase K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D AFE_2945 msrB; methionine-R-sulfoxide reductase K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]
D AFE_2773 yghU; glutathione S-transferase family protein YghU K11209 yghU; GSH-dependent disulfide-bond oxidoreductase [EC:1.8.4.-]
D AFE_1468 antioxidant, AhpC/Tsa family K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D AFE_3224 pirin family protein K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24]
D AFE_2481 merA; mercuric reductase K00520 merA; mercuric reductase [EC:1.16.1.1]
D AFE_3153 cyc2; cytochrome c K20150 cyc2; iron:rusticyanin reductase [EC:1.16.9.1]
D AFE_2860 arsC; arsenate reductase K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D AFE_0574 radical SAM domain protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D AFE_2720 nrdG; anaerobic ribonucleoside-triphosphate reductase, beta subunit K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D AFE_2149 hyfB; hydrogenase-4, B subunit K12137 hyfB; hydrogenase-4 component B [EC:1.-.-.-]
D AFE_2151 hyfE; hydrogenase-4, E subunit K12140 hyfE; hydrogenase-4 component E [EC:1.-.-.-]
D AFE_2152 hyfF; hydrogenase-4, F subunit K12141 hyfF; hydrogenase-4 component F [EC:1.-.-.-]
D AFE_2136 pcm-1; protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D AFE_0469 pcm-2; protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D AFE_2929 cfa; cyclopropane-fatty-acyl-phospholipid synthase K00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79]
D AFE_2437 cyclopropane-fatty-acyl-phospholipid synthase domain protein K00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79]
D AFE_3216 conserved hypothetical protein K16868 tehB; tellurite methyltransferase [EC:2.1.1.265]
D AFE_0601 cutE; apolipoprotein N-acyltransferase K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269]
D AFE_0727 1-acyl-sn-glycerol-3-phosphate acyltransferase K22617 olsA; lyso-ornithine lipid O-acyltransferase [EC:2.3.1.270]
D AFE_0248 aat; leucyl/phenylalanyl-tRNA--protein transferase K00684 aat; leucyl/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6]
D AFE_0249 ate; arginine-tRNA--protein transferase K21420 bpt; leucyl-tRNA---protein transferase [EC:2.3.2.29]
D AFE_1524 draT; NAD(+)--dinitrogen-reductase ADP-D-ribosyltransferase K05951 draT; NAD+---dinitrogen-reductase ADP-D-ribosyltransferase [EC:2.4.2.37]
D AFE_1544 pyrophosphorylase, putative K03813 modD; molybdenum transport protein [EC:2.4.2.-]
D AFE_2186 lgt; prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]
D AFE_1458 pleiotropic regulatory protein, putative K20084 gnnB; UDP-N-acetyl-3-dehydro-alpha-D-glucosamine 3-aminotranferase [EC:2.6.1.122]
D AFE_0548 glnE; glutamate-ammonia-ligase adenylyltransferase K00982 glnE; [glutamine synthetase] adenylyltransferase / [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase [EC:2.7.7.42 2.7.7.89]
D AFE_0519 conserved hypothetical protein K08997 SELENOO; protein adenylyltransferase [EC:2.7.7.108]
D AFE_2412 phosphoenolpyruvate-utilizing enzyme mobile domain protein K22579 rph; rifampicin phosphotransferase [EC:2.7.9.6]
D AFE_3022 hprK; Hpr(Ser) kinase/phosphatase K06023 hprK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-]
D AFE_0063 ybgC; tol-pal system-associated acyl-CoA thioesterase K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D AFE_1341 protein-tyrosine phosphatase, putative K01104 E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48]
D AFE_0987 conserved hypothetical protein K07053 E3.1.3.97; 3',5'-nucleoside bisphosphate phosphatase [EC:3.1.3.97]
D AFE_2314 sixA; phosphohistidine phosphatase SixA K08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-]
D AFE_2387 hydrolase, TatD family K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D AFE_0992 hydrolase, TatD family K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D AFE_1525 draG; ADP-ribosyl-[dinitrogen reductase] hydrolase K05521 draG; ADP-ribosyl-[dinitrogen reductase] hydrolase [EC:3.2.2.24]
D AFE_0438 def-1; polypeptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D AFE_0019 def-2; polypeptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D AFE_0551 hydrolase, carbon-nitrogen family K11206 NIT1; deaminated glutathione amidase [EC:3.5.1.128]
D AFE_1874 adenylate cyclase K18446 ygiF; triphosphatase [EC:3.6.1.25]
D AFE_1882 maf-2; maf protein K25422 yceF; 7-methyl-GTP pyrophosphatase [EC:3.6.1.-]
D AFE_1923 YjeF-related protein K17758 nnrD; ADP-dependent NAD(P)H-hydrate dehydratase [EC:4.2.1.136]
D AFE_0645 mpl; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase K02558 mpl; UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase [EC:6.3.2.45]
D AFE_2439 copper-translocating P-type ATPase K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]
D AFE_2779 copper-translocating P-type ATPase K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]
D AFE_2944 cation transporting P-type ATPase K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10]
D AFE_2327 magnesium-translocating P-type ATPase K01531 mgtA; P-type Mg2+ transporter [EC:7.2.2.14]
C 99981 Carbohydrate metabolism
D AFE_0926 sfsA; sugar fermentation stimulation protein K06206 sfsA; sugar fermentation stimulation protein A
D AFE_2534 histone deacetylase family protein K04768 acuC; acetoin utilization protein AcuC
C 99982 Energy metabolism
D AFE_0690 fdhD-2; formate dehydrogenase family accessory protein FdhD K02379 fdhD; FdhD protein
D AFE_1654 fdhD-1; formate dehydrogenase family accessory protein FdhD K02379 fdhD; FdhD protein
D AFE_0678 fdx; ferredoxin, 2Fe-2S K04755 fdx; ferredoxin, 2Fe-2S
D AFE_1541 ferredoxin, putative K04755 fdx; ferredoxin, 2Fe-2S
D AFE_1844 ferredoxin K05524 fdxA; ferredoxin
D AFE_0014 ferredoxin K05524 fdxA; ferredoxin
D AFE_0984 ferredoxin K05524 fdxA; ferredoxin
D AFE_1519 ferredoxin K11107 yfaE; ferredoxin
D AFE_0674 iscU; FeS cluster assembly scaffold protein IscU K04488 iscU; nitrogen fixation protein NifU and related proteins
D AFE_1508 nitrogen fixation protein nifU K13819 K13819; NifU-like protein
D AFE_1511 nitrogen fixation protein NifQ K15790 nifQ; nitrogen fixation protein NifQ
D AFE_1677 von Willebrand factor type A domain protein K02448 norD; nitric oxide reductase NorD protein
D AFE_2157 von Willebrand factor type A domain protein K02448 norD; nitric oxide reductase NorD protein
D AFE_3054 von Willebrand factor type A domain protein K02448 norD; nitric oxide reductase NorD protein
D AFE_2535 von Willebrand factor type A domain protein K02448 norD; nitric oxide reductase NorD protein
D AFE_2536 CbbQ/NirQ/NorQ/GpvN family protein K04748 norQ; nitric oxide reductase NorQ protein
D AFE_1678 p30; p30 protein K04748 norQ; nitric oxide reductase NorQ protein
D AFE_2156 cbbQ-2; CbbQ protein K04748 norQ; nitric oxide reductase NorQ protein
D AFE_3053 cbbQ-1; CbbQ protein K04748 norQ; nitric oxide reductase NorQ protein
D AFE_1515 nifX; nitrogen fixation protein NifX K02596 nifX; nitrogen fixation protein NifX
D AFE_1538 nitrogen fixation protein, putative K02593 nifT; nitrogen fixation protein NifT
D AFE_1535 NifZ domain protein K02597 nifZ; nitrogen fixation protein NifZ
D AFE_1536 NifZ domain protein K02597 nifZ; nitrogen fixation protein NifZ
D AFE_1529 nifB; nitrogenase cofactor biosynthesis protein NifB K02585 nifB; nitrogen fixation protein NifB
D AFE_1516 nifN; nitrogenase molybdenum-iron cofactor biosynthesis protein NifN K02592 nifN; nitrogenase molybdenum-iron protein NifN
D AFE_1517 nifE; nitrogenase MoFe cofactor biosynthesis protein NifE K02587 nifE; nitrogenase molybdenum-cofactor synthesis protein NifE
D AFE_1480 fixA; electron transfer flavoprotein, beta subunit K03521 fixA; electron transfer flavoprotein beta subunit
D AFE_1477 fixX; ferredoxin-like protein K03855 fixX; ferredoxin like protein
D AFE_1504 nifW protein, putative K02595 nifW; nitrogenase-stabilizing/protective protein
D AFE_3146 rus; rusticyanin K18683 rus; rusticyanin
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
D AFE_0263 conserved hypothetical protein TIGR00044 K06997 yggS; PLP dependent protein
C 99986 Glycan metabolism
D AFE_0304 conserved hypothetical protein K08992 lapA; lipopolysaccharide assembly protein A
D AFE_0577 membrane protein, putative K07027 K07027; glycosyltransferase 2 family protein
C 99987 Cofactor metabolism
D AFE_0305 ubiB; 2-polyprenylphenol 6-hydroxylase K03688 ubiB; ubiquinone biosynthesis protein
D AFE_2390 conserved hypothetical protein K09806 ubiK; ubiquinone biosynthesis accessory factor UbiK
D AFE_2724 conserved hypothetical protein K24843 ubiT; O2-independent ubiquinone biosynthesis accessory factor UbiT
D AFE_2077 mobB; molybdopterin-guanine dinucleotide biosynthesis protein B K03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein
D AFE_0280 conserved hypothetical protein K18588 COQ10; coenzyme Q-binding protein COQ10
C 99988 Secondary metabolism
D AFE_2803 FMN reductase, NADPH-dependent K19784 chrR; chromate reductase, NAD(P)H dehydrogenase (quinone)
C 99999 Others
D AFE_0098 DoxD family protein/pyridine nucleotide-disulfide oxidoreductase K15977 K15977; putative oxidoreductase
D AFE_0959 phospholipase/carboxylesterase K06999 K06999; phospholipase/carboxylesterase
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D AFE_0590 cold-shock protein K03704 cspA; cold shock protein
D AFE_1326 conserved hypothetical protein K07741 antB; anti-repressor protein
D AFE_2240 glnK-2; nitrogen regulatory protein P-II 2 K04752 glnK; nitrogen regulatory protein P-II 2
D AFE_2915 glnK-1; nitrogen regulatory protein P-II 2 K04752 glnK; nitrogen regulatory protein P-II 2
C 99974 Translation
D AFE_2679 metallo-beta-lactamase family protein K07576 K07576; metallo-beta-lactamase family protein
C 99975 Protein processing
D AFE_0521 ATP-dependent Clp protease adaptor protein ClpS K06891 clpS; ATP-dependent Clp protease adaptor protein ClpS
D AFE_0909 tig; trigger factor K03545 tig; trigger factor
D AFE_0277 smpB; SsrA-binding protein K03664 smpB; SsrA-binding protein
D AFE_3289 hypC-2; hydrogenase assembly chaperone HypC K04653 hypC; hydrogenase expression/formation protein HypC
D AFE_0713 hypC-1; hydrogenase assembly chaperone HypC K04653 hypC; hydrogenase expression/formation protein HypC
D AFE_3290 hypD-2; hydrogenase expression/formation protein HypD K04654 hypD; hydrogenase expression/formation protein HypD
D AFE_0715 hypD-1; hydrogenase expression/formation protein HypD K04654 hypD; hydrogenase expression/formation protein HypD
D AFE_0716 hypE; hydrogenase expression/formation protein HypE K04655 hypE; hydrogenase expression/formation protein HypE
D AFE_0712 hypF; [NiFe] hydrogenase maturation protein HypF K04656 hypF; hydrogenase maturation protein HypF
D AFE_2903 conserved hypothetical protein K07395 K07395; putative proteasome-type protease
D AFE_3241 OsmC/Ohr family protein K07397 yhfA; putative redox protein
D AFE_3112 resB; cytochrome c-type biogenesis protein ResB K07399 resB; cytochrome c biogenesis protein
D AFE_0780 xanthine dehydrogenase accessory factor, putative K07402 xdhC; xanthine dehydrogenase accessory factor
C 99976 Replication and repair
D AFE_1304 transposon, resolvase K07450 K07450; putative resolvase
D AFE_1033 transposon, resolvase K07450 K07450; putative resolvase
D AFE_1105 transposon, resolvase K07450 K07450; putative resolvase
D AFE_0358 radC; DNA repair protein RadC K03630 radC; DNA repair protein RadC
D AFE_3259 DNA recombination protein RmuC, putative K09760 rmuC; DNA recombination protein RmuC
D AFE_1794 base excision repair protein, HhH-GPD family K07457 K07457; endonuclease III related protein
D AFE_0142 conserved hypothetical protein TIGR00252 K07460 yraN; putative endonuclease
D AFE_0017 DNA processing protein DprA, putative K04096 smf; DNA processing protein
D AFE_0379 ATPase, AAA family K07478 ycaJ; putative ATPase
D AFE_2829 conserved hypothetical protein K07501 K07501; 3'-5' exonuclease
D AFE_1709 ISAfe4, tranposase orf1 K07483 K07483; transposase
D AFE_1610 ISAfe7, transposase orfA K07483 K07483; transposase
D AFE_2393 ISAfe5, transposase orfA K07483 K07483; transposase
D AFE_2469 ISAfe4, transposase orf2 K07484 K07484; transposase
D AFE_1706 ISAfe4, transposase orf3 K07484 K07484; transposase
D AFE_2938 ISAfe4, transposase orf2 K07484 K07484; transposase
D AFE_1708 ISAfe4, transposase orf2 K07484 K07484; transposase
D AFE_3154 ISAfe4, transposase orf3, degenerate K07484 K07484; transposase
D AFE_2470 ISAfe4, transposase orf3 K07484 K07484; transposase
D AFE_1895 ISAfe1, transposase K07486 K07486; transposase
D AFE_0550 ISAfe3, transposase K07486 K07486; transposase
D AFE_1265 ISAfe3, transposase K07486 K07486; transposase
D AFE_1110 ISAfe3, transposase K07486 K07486; transposase
D AFE_1142 ISAfe3, transposase K07486 K07486; transposase
D AFE_3183 ISAfe1, transposase K07486 K07486; transposase
D AFE_3263 ISAfe3, transposase K07486 K07486; transposase
D AFE_2972 ISAfe3, transposase K07486 K07486; transposase
D AFE_2432 ISAfe3, transposase K07486 K07486; transposase
D AFE_2709 ISAfe3, transposase K07486 K07486; transposase
D AFE_1330 ISAfe2, transposase K07493 K07493; putative transposase
D AFE_1058 ISAfe8, transposase K07496 K07496; putative transposase
D AFE_1034 transposon, transposase K07496 K07496; putative transposase
D AFE_1215 ISAfe8, transposase K07496 K07496; putative transposase
D AFE_1328 transposase, IS605 OrfB family protein, putative K07496 K07496; putative transposase
D AFE_2505 transposon, transposition protein B, putative K07497 K07497; putative transposase
D AFE_0832 conserved hypothetical protein K07497 K07497; putative transposase
D AFE_0689 transposase, degenerate K07497 K07497; putative transposase
D AFE_0506 hypothetical protein K07497 K07497; putative transposase
D AFE_2400 hypothetical protein K07497 K07497; putative transposase
D AFE_2778 hypothetical protein K07497 K07497; putative transposase
C 99979 Viral proteins
C 99998 Others
D AFE_2017 PspA/IM30 family K03969 pspA; phage shock protein A
D AFE_1920 conserved hypothetical protein TIGR00103 K09747 ebfC; nucleoid-associated protein EbfC
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D AFE_0719 amino acid permease family protein K03294 TC.APA; basic amino acid/polyamine antiporter, APA family
D AFE_3262 transporter, AcrB/AcrD/AcrF family K03296 TC.HAE1; hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 family
D AFE_0771 cytosine/purines/uracil/thiamine/allantoin permease family protein K03457 TC.NCS1; nucleobase:cation symporter-1, NCS1 family
C 99978 Cell growth
D AFE_0667 ispZ; intracellular septation protein A K06190 ispZ; intracellular septation protein
D AFE_2913 SpoVR like family protein K06415 spoVR; stage V sporulation protein R
D AFE_0525 M23/M37 peptidase domain protein K22719 envC; murein hydrolase activator
C 99993 Cell motility
C 99995 Signaling proteins
D AFE_2740 typA; GTP-binding protein TypA K06207 typA; GTP-binding protein
D AFE_0597 PhoH-like protein K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins
D AFE_1469 PhoH family protein K07175 phoH2; PhoH-like ATPase
D AFE_2910 conserved hypothetical protein K07180 prkA; serine protein kinase
D AFE_0977 conserved hypothetical protein K09767 yajQ; cyclic-di-GMP-binding protein
D AFE_1762 conserved hypothetical protein K09767 yajQ; cyclic-di-GMP-binding protein
C 99992 Structural proteins
D AFE_0377 outer membrane lipoprotein carrier protein LolA, putative K03634 lolA; outer membrane lipoprotein carrier protein
D AFE_2763 outer membrane lipoprotein LolB, putative K02494 lolB; outer membrane lipoprotein LolB
D AFE_2113 vacJ lipoprotein K04754 mlaA; phospholipid-binding lipoprotein MlaA
D AFE_1453 outer membrane protein, OmpH family K06142 hlpA; outer membrane protein
D AFE_3013 capsule polysaccharide modification protein K07265 kpsS; capsular polysaccharide export protein
D AFE_3012 capsule polysaccharide biosynthesis protein K07266 kpsC; capsular polysaccharide export protein
D AFE_2054 conserved hypothetical protein K07283 ydiY; putative salt-induced outer membrane protein
D AFE_2316 outer membrane lipoprotein Slp, putative K07285 slp; outer membrane lipoprotein
D AFE_0100 conserved hypothetical protein K02005 ABC.CD.TX; HlyD family secretion protein
D AFE_3071 hypothetical protein K04062 osmB; osmotically inducible lipoprotein OsmB
D AFE_1932 conserved hypothetical protein K15539 rodZ; cytoskeleton protein RodZ
D AFE_1798 membrane protein, putative K21908 hdeD; membrane protein HdeD
C 99994 Others
D AFE_1440 phoU; phosphate transport system protein PhoU K02039 phoU; phosphate transport system protein
D AFE_0960 mdoG; periplasmic glucans biosynthesis protein, MdoG K03670 mdoG; periplasmic glucans biosynthesis protein
D AFE_2282 phnK; phosphonate ABC transporter, ATP-binding protein PhnK K05781 phnK; putative phosphonate transport system ATP-binding protein
D AFE_2738 apaG protein K06195 apaG; ApaG protein
D AFE_2195 cyaY; cyaY protein K06202 cyaY; iron-sulfur cluster assembly protein CyaY
B
B 09194 Poorly characterized
C 99996 General function prediction only
D AFE_2065 CvpA family protein K03558 cvpA; membrane protein required for colicin V production
D AFE_0721 conserved hypothetical protein K06886 glbN; hemoglobin
D AFE_1548 heme-binding protein, putative K06886 glbN; hemoglobin
D AFE_1482 conserved domain protein K06886 glbN; hemoglobin
D AFE_0681 patatin-like phospholipase family protein K07001 K07001; NTE family protein
D AFE_1022 patatin-like phospholipase family protein K07001 K07001; NTE family protein
D AFE_2227 HAD-superfamily hydrolase, subfamily IA K07025 K07025; putative hydrolase of the HAD superfamily
D AFE_3067 iron-sulfur cluster assembly accessory protein K15724 erpA; iron-sulfur cluster insertion protein
D AFE_1902 yihY; YihY family protein K07058 K07058; membrane protein
D AFE_3103 phosphoribosyl transferase domain protein K07100 K07100; putative phosphoribosyl transferase
D AFE_0923 conserved hypothetical protein K07153 hflD; high frequency lysogenization protein
D AFE_2857 arsH; arsenical resistance protein ArsH K11811 arsH; arsenical resistance protein ArsH
D AFE_0016 smg family protein K03747 smg; Smg protein
D AFE_2527 membrane protein, DedA family K03975 dedA; membrane-associated protein
D AFE_1136 membrane protein, DedA family K03975 dedA; membrane-associated protein
D AFE_2438 conserved hypothetical protein K08982 K08982; putative membrane protein
D AFE_1333 conserved hypothetical protein K08982 K08982; putative membrane protein
D AFE_2159 phnA; alkylphosphonate utilization operon protein PhnA K06193 phnA; protein PhnA
C 99997 Function unknown
D AFE_2777 conserved domain protein K06889 K06889; uncharacterized protein
D AFE_0668 conserved hypothetical protein K06923 K06923; uncharacterized protein
D AFE_2576 small GTP-binding protein K06945 K06945; uncharacterized protein
D AFE_2897 hypothetical protein K06950 K06950; uncharacterized protein
D AFE_1839 conserved hypothetical protein K06996 K06996; uncharacterized protein
D AFE_2118 membrane protein, putative K07003 K07003; uncharacterized protein
D AFE_3237 conserved hypothetical protein K07018 K07018; uncharacterized protein
D AFE_0724 hydrolase, alpha/beta hydrolase fold family K07019 K07019; uncharacterized protein
D AFE_3269 conserved hypothetical protein TIGR00305 K07063 K07063; uncharacterized protein
D AFE_0086 conserved hypothetical protein K07064 K07064; uncharacterized protein
D AFE_2984 PIN domain protein K07064 K07064; uncharacterized protein
D AFE_1945 membrane protein, putative K07090 K07090; uncharacterized protein
D AFE_2258 membrane protein, putative K07090 K07090; uncharacterized protein
D AFE_2775 membrane protein K07090 K07090; uncharacterized protein
D AFE_2351 membrane protein, putative K07090 K07090; uncharacterized protein
D AFE_0764 membrane protein, putative K07090 K07090; uncharacterized protein
D AFE_2548 conserved hypothetical protein K07092 K07092; uncharacterized protein
D AFE_0363 conserved hypothetical protein K07092 K07092; uncharacterized protein
D AFE_2508 conserved hypothetical protein K07092 K07092; uncharacterized protein
D AFE_0053 membrane protein, putative K07112 K07112; uncharacterized protein
D AFE_0143 lipoprotein, putative K07121 K07121; uncharacterized protein
D AFE_2513 conserved hypothetical protein K07126 K07126; uncharacterized protein
D AFE_0117 conserved domain protein K07126 K07126; uncharacterized protein
D AFE_0409 conserved domain protein K07126 K07126; uncharacterized protein
D AFE_0303 conserved domain protein K07126 K07126; uncharacterized protein
D AFE_2686 conserved domain protein K07126 K07126; uncharacterized protein
D AFE_2578 roadblock/LC7 domain protein K07131 K07131; uncharacterized protein
D AFE_0401 roadblock/LC7 domain protein K07131 K07131; uncharacterized protein
D AFE_0978 roadblock/LC7 domain protein K07131 K07131; uncharacterized protein
D AFE_2345 ATP-dependent protease La domain protein K07157 K07157; uncharacterized protein
D AFE_0033 conserved hypothetical protein TIGR00278 K08998 K08998; uncharacterized protein
D AFE_2749 conserved hypothetical protein K09004 K09004; uncharacterized protein
D AFE_2872 conserved hypothetical protein K09005 K09005; uncharacterized protein
D AFE_2339 GatB/Yqey domain protein K09117 K09117; uncharacterized protein
D AFE_0260 conserved hypothetical protein TIGR00251, putative K09131 K09131; uncharacterized protein
D AFE_2927 conserved hypothetical protein K09137 K09137; uncharacterized protein
D AFE_0573 conserved hypothetical protein TIGR00296 K09141 K09141; uncharacterized protein
D AFE_2347 conserved hypothetical protein K09700 K09700; uncharacterized protein
D AFE_3267 YaiI/YqxD family protein K09768 K09768; uncharacterized protein
D AFE_0666 YCII-related domain protein K09780 K09780; uncharacterized protein
D AFE_2912 conserved hypothetical protein K09786 K09786; uncharacterized protein
D AFE_0490 conserved hypothetical protein K09791 K09791; uncharacterized protein
D AFE_1761 conserved hypothetical protein K09794 K09794; uncharacterized protein
D AFE_2414 conserved hypothetical protein K09803 K09803; uncharacterized protein
D AFE_1661 conserved hypothetical protein K09822 K09822; uncharacterized protein
D AFE_2745 conserved hypothetical protein K09921 K09921; uncharacterized protein
D AFE_0482 conserved hypothetical protein K09928 K09928; uncharacterized protein
D AFE_2891 conserved hypothetical protein K09940 K09940; uncharacterized protein
D AFE_1743 conserved hypothetical protein K09959 K09959; uncharacterized protein
D AFE_2830 conserved hypothetical protein K09978 K09978; uncharacterized protein
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: April 24, 2024