+F Repair protein KO
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DNA Repair and Recombination Proteins - Alteromonas mediterranea DE1
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D amad1_19170 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D amad1_10790 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D amad1_10800 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E amad1_15405 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E amad1_01370 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E amad1_06490 Endonuclease III/Nth K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
D amad1_01030 putative S1/P1 Nuclease K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D amad1_15055 mutator mutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D amad1_19170 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D amad1_10790 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D amad1_10800 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D amad1_10805 deoxyribodipyrimidine photolyase-like protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E amad1_15405 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E amad1_19175 ada regulatory protein K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E amad1_01370 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E amad1_00045 3-methyl-adenine DNA glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E amad1_00275 formamidopyrimidine/5-formyluracil/5-hydroxymethyluracil DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E amad1_06490 Endonuclease III/Nth K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E amad1_08390 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E amad1_03720 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E amad1_10190 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E amad1_00075 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E amad1_01080 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E amad1_15425 putative excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E amad1_06535 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E amad1_10975 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E amad1_21743 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E amad1_00975 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E amad1_00075 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E amad1_10190 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F amad1_18535 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F amad1_18530 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F amad1_17885 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F amad1_00710 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F amad1_08355 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E amad1_04590 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E amad1_18795 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E amad1_03065 DNA mismatch repair protein K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E amad1_08515 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E amad1_13715 exonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E amad1_13310 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E amad1_04900 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E amad1_00015 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E amad1_15995 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E amad1_09775 putative DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E amad1_09130 DNA polymerase III subunit delta K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E amad1_19400 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E amad1_05810 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E amad1_17470 putative DNA polymerase K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E amad1_08960 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D DNA ligase
E amad1_10190 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E amad1_21743 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E amad1_00975 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E amad1_01135 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E amad1_06125 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E amad1_16060 D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E amad1_02285 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E amad1_11920 exodeoxyribonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E amad1_11925 exodeoxyribonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E amad1_11915 exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E amad1_04600 recombinase A K03553 recA; recombination protein RecA
E amad1_06910 Holliday junction DNA helicase motor protein K03550 ruvA; holliday junction DNA helicase RuvA
E amad1_06915 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E amad1_06905 Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E amad1_18270 primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E amad1_20490 flavodoxin K02317 dnaT; DNA replication protein DnaT
E amad1_08515 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E amad1_04215 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E amad1_04210 exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E amad1_04600 recombinase A K03553 recA; recombination protein RecA
E amad1_13385 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E amad1_00020 recombinational DNA repair ATPase K03629 recF; DNA replication and repair protein RecF
E amad1_00730 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E amad1_03720 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E amad1_03730 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E amad1_13150 recombination protein RecR K06187 recR; recombination protein RecR
E amad1_07440 DNA repair ATPase RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E amad1_21963 hypothetical protein K03554 rdgC; recombination associated protein RdgC
E amad1_03545 rdgC; recombination associated protein K03554 rdgC; recombination associated protein RdgC
E amad1_06910 Holliday junction DNA helicase motor protein K03550 ruvA; holliday junction DNA helicase RuvA
E amad1_06915 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E amad1_06905 Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E amad1_04215 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E amad1_04210 exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F amad1_11145 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F amad1_00025 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F amad1_09910 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F amad1_13635 histone-like DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F amad1_08575 RecT protein K07455 recT; recombination protein RecT
F amad1_03720 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F amad1_03730 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F amad1_13150 recombination protein RecR K06187 recR; recombination protein RecR
F amad1_10190 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F amad1_19445 transcriptional activator Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F amad1_08320 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F amad1_11115 integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F amad1_08515 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F amad1_14555 RecQ domain-containing protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F amad1_00955 ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F amad1_02910 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F amad1_01080 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F amad1_15425 putative excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F amad1_06535 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F amad1_11560 DNA-binding protein, H-NS family K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D amad1_17335 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D amad1_21303 umuC protein K03502 umuC; DNA polymerase V
D amad1_05800 DNA repair protein K03502 umuC; DNA polymerase V
D amad1_21298 putative prophage repressor K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D amad1_05805 putative prophage repressor K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D amad1_04600 recombinase A K03553 recA; recombination protein RecA
D amad1_19945 LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D amad1_07440 DNA repair ATPase RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D amad1_16910 DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D amad1_00190 DNA repair nucleotidyltransferase/DNA polymerase K14161 imuB; protein ImuB
D amad1_00185 DNA polymerase III subunit alpha K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D amad1_01135 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D amad1_06125 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D amad1_05475 Regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D amad1_00360 ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D amad1_12995 ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D amad1_18680 ATP-dependent RNA helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D amad1_15055 mutator mutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D amad1_11155 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D amad1_11160 nrdB; ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024