+F Repair protein KO
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DNA Repair and Recombination Proteins - Brevibacillus brevis
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D BBR47_10750 ogt; probable methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D BBR47_54810 phr; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E BBR47_55370 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E BBR47_10260 probable A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E BBR47_10660 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E BBR47_40440 putative ATP-dependent helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D BBR47_25420 putative hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BBR47_38130 ytkD; nucleoside triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BBR47_11040 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BBR47_48460 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BBR47_43000 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BBR47_47540 putative ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BBR47_15250 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BBR47_25480 dut; putative deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D BBR47_10750 ogt; probable methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D BBR47_26070 ada; regulatory protein ADA K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D BBR47_03220 adaA; AdaA protein K13530 adaA; AraC family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase [EC:2.1.1.-]
D BBR47_41880 adaB; probable methylated-DNA--protein-cysteine methyltransferase K13531 adaB; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D BBR47_54810 phr; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E BBR47_55370 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E BBR47_22060 conserved hypothetical protein K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E BBR47_09260 putative DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E BBR47_03210 alkA; DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E BBR47_10260 probable A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E BBR47_51070 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E BBR47_14060 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E BBR47_55330 putative formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E BBR47_10660 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E BBR47_03090 exoA; exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E BBR47_21870 putative endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E BBR47_03200 nfo; endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E BBR47_44380 probable endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E BBR47_18800 conserved hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E BBR47_06860 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E BBR47_14050 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E BBR47_52770 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E BBR47_52780 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E BBR47_16800 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E BBR47_06850 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BBR47_11530 helD; probable DNA helicase involved in recombination K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BBR47_33040 conserved hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BBR47_40220 putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BBR47_14050 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E BBR47_06860 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F BBR47_02110 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F BBR47_02120 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F BBR47_02480 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F BBR47_54930 rpoE; DNA-directed RNA polymerase delta chain K03048 rpoE; DNA-directed RNA polymerase subunit delta
F BBR47_37330 DNA-directed RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F BBR47_01030 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E BBR47_33760 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E BBR47_16440 mutSB; DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2
E BBR47_39630 MutS2 family protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E BBR47_33750 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E BBR47_23380 xseA; probable exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E BBR47_23390 xseB; probable exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E BBR47_13770 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E BBR47_34380 polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E BBR47_00020 dnaN; DNA polymerase III beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E BBR47_20020 yqeN; conserved hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E BBR47_00780 holB; DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E BBR47_09030 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E BBR47_00640 dnaX; DNA polymerase III gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E BBR47_06860 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E BBR47_06850 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BBR47_11530 helD; probable DNA helicase involved in recombination K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BBR47_33040 conserved hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BBR47_40220 putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BBR47_59230 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E BBR47_35630 putative methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E BBR47_18960 conserved hypothetical protein K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E BBR47_33960 recA; RecA protein K03553 recA; recombination protein RecA
E BBR47_18650 ruvA; Holliday junction ATP-dependent DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E BBR47_18660 ruvB; Holliday junction ATP-dependent DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E BBR47_18640 ruvC; crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E BBR47_37310 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E BBR47_49760 sbcC; putative nuclease sbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E BBR47_49770 sbcD; putative exonuclease sbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
E BBR47_48030 hypothetical protein K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E BBR47_33960 recA; RecA protein K03553 recA; recombination protein RecA
E BBR47_01890 radA; probable DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E BBR47_00040 recF; DNA replication and repair protein F K03629 recF; DNA replication and repair protein RecF
E BBR47_37070 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E BBR47_34970 hypothetical protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E BBR47_18800 conserved hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E BBR47_20680 recO; DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
E BBR47_00660 recR; recombination protein RecR K06187 recR; recombination protein RecR
E BBR47_23460 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E BBR47_18650 ruvA; Holliday junction ATP-dependent DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E BBR47_18660 ruvB; Holliday junction ATP-dependent DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E BBR47_18640 ruvC; crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E BBR47_49740 addA; ATP-dependent nuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E BBR47_49750 addB; ATP-dependent nuclease subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E BBR47_49760 sbcC; putative nuclease sbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E BBR47_49770 sbcD; putative exonuclease sbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
E BBR47_48030 hypothetical protein K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E BBR47_36410 ykoV; YkoV protein K10979 ku; DNA end-binding protein Ku
E BBR47_36460 ligB; putative ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E BBR47_36590 conserved hypothetical protein K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F BBR47_00110 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F BBR47_00060 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F BBR47_34920 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F BBR47_24580 hbs; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F BBR47_35670 hypothetical protein K07455 recT; recombination protein RecT
F BBR47_18800 conserved hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F BBR47_20680 recO; DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
F BBR47_00660 recR; recombination protein RecR K06187 recR; recombination protein RecR
F BBR47_06860 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F BBR47_24270 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F BBR47_56740 recQ; probable ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F BBR47_52770 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F BBR47_52780 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D BBR47_19820 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D BBR47_33960 recA; RecA protein K03553 recA; recombination protein RecA
D BBR47_33080 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D BBR47_23460 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D BBR47_59230 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D BBR47_33950 recX; regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D BBR47_25060 dinG; probable ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D BBR47_26660 putative ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D BBR47_25420 putative hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BBR47_38130 ytkD; nucleoside triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BBR47_11040 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BBR47_48460 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BBR47_43000 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BBR47_47540 putative ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BBR47_15250 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BBR47_25480 dut; putative deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D BBR47_31350 nrdE; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D BBR47_31340 nrdF; ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D BBR47_16120 conserved hypothetical protein K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D BBR47_34300 ytqI; bifunctional protein YtqI K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024