+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Beijerinckia indica</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
C    Bind_2674 type I site-specific deoxyribonuclease, HsdR family	K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] 
C    Bind_2673 restriction modification system DNA specificity domain	K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] 
C    Bind_2672 N-6 DNA methylase	K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] 
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      Bind_0750 DNA methylase N-4/N-6 domain protein	K13581 ccrM; modification methylase [EC:2.1.1.72] 
D      Bind_0019 D12 class N6 adenine-specific DNA methyltransferase	K07318 K07318; adenine-specific DNA-methyltransferase [EC:2.1.1.72] 
D      Bind_0766 DNA-cytosine methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
B  Type III R-M system
B  Type IV R-M system
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
D      Bind_1043 transcriptional modulator of MazE/toxin, MazF	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
D      Bind_3610 transcriptional regulator/antitoxin, MazE	K07172 mazE; antitoxin MazE 
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
D      Bind_3688 addiction module toxin, RelE/StbE family	K06218 relE; mRNA interferase RelE/StbE 
D      Bind_2414 plasmid stabilization system	K06218 relE; mRNA interferase RelE/StbE 
D      Bind_1680 hypothetical protein	K06218 relE; mRNA interferase RelE/StbE 
D      Bind_3687 prevent-host-death family protein	K18923 stbD; antitoxin StbD 
C    YafQ-dinJ
D      Bind_3758 addiction module antitoxin, RelB/DinJ family	K07473 dinJ; DNA-damage-inducible protein J 
C    YoeB-YefM
C    HipA-HipB
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
D      Bind_3759 plasmid stabilization system	K19092 parE1_3_4; toxin ParE1/3/4 
C    Doc-Phd
C    HigB-HigA
D      Bind_1543 conserved hypothetical protein	K18831 higA; HTH-type transcriptional regulator / antitoxin HigA 
D      Bind_3283 putative plasmid maintenance system antidote protein, XRE family	K21498 higA-1; antitoxin HigA-1 
C    MqsR-MqsA
C    VapC-VapB
D      Bind_1916 SpoVT/AbrB-like protein	K18829 mvpT; antitoxin VapB 
D      Bind_3708 PilT protein domain protein	K19686 vapC; ribonuclease VapC [EC:3.1.-.-] 
D      Bind_3707 Rv0623 family protein transcription factor	K19687 vapB; antitoxin VapB 
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
D      Bind_2539 PilT protein domain protein	K07062 fitB; toxin FitB [EC:3.1.-.-] 
D      Bind_3526 PilT protein domain protein	K07062 fitB; toxin FitB [EC:3.1.-.-] 
D      Bind_2795 PilT protein domain protein	K07062 fitB; toxin FitB [EC:3.1.-.-] 
D      Bind_2796 plasmid stability protein	K21495 fitA; antitoxin FitA 
C    BC_0920-BC_0921
C    Type II TA system related factors
D      Bind_0698 cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      Bind_1944 DNA topoisomerase IV, A subunit	K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] 
D      Bind_1215 DNA topoisomerase IV, B subunit	K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] 
D      Bind_3674 glutamyl-tRNA synthetase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
D      Bind_1410 glutamyl-tRNA synthetase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
D      Bind_0893 protein of unknown function DUF339	K09159 cptB; antitoxin CptB 
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    Bind_0097 aminotransferase class V	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
C    Bind_0403 aminotransferase class V	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023