+C Kinase KO
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Protein Kinases - Brugia malayi (filaria)
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ASerine/threonine kinases: AGC group
B PKA family
C BM_BM7586 Bma-kin-1; cAMP-dependent protein kinase catalytic subunit, putative K04345 PKA; protein kinase A [EC:2.7.11.11]
C BM_BM4184 Bm4184; Uncharacterized protein K19584 PRKX; protein kinase X [EC:2.7.11.11]
B PKG family
B PKC family [OT]
C BM_BM4529 Bma-pkc-1; Uncharacterized protein K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
C BM_BM3221 Bma-pkc-3; protein kinase C3,putative K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
B PKN family
C BM_BM4152 Bma-pkn-1; Hr1 repeat family protein K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
B AUR family [OT]
C BM_BM8041 Bm8041; serine/threonine protein kinase 6, putative K11481 AURKA; aurora kinase A [EC:2.7.11.1]
C BM_BM1708 Bma-air-2; serine/threonine kinase 12, putative K11479 AURKB; aurora kinase B [EC:2.7.11.1]
B PDK1 family
C BM_BM4698 Bma-pdk-1; Uncharacterized protein K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
B AKT/PKB family
C BM_BM2161 Bma-akt-1; Uncharacterized protein K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
B SGK family [OT]
B RSK family [OT]
C BM_BM8603 Bma-rskn-1; ribosomal protein S6 kinase alpha 3, putative K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
C BM_BM2936 Bma-rskn-2; Protein kinase domain containing protein K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
C BM_BM6597 Bma-rsks-1; Uncharacterized protein K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
B NDR family
C BM_BM5354 Bma-sax-1; Protein kinase domain containing protein K08790 STK38; serine/threonine kinase 38 [EC:2.7.11.1]
B MAST family [OT]
C BM_BM2129 Bma-kin-4; KIAA0303, putative K08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]
B YANK family
C BM_BM5078 Bm5078; Uncharacterized protein K08793 STK32; serine/threonine kinase 32 [EC:2.7.11.1]
B DMPK family [OT]
B GRK family [OT]
C BM_BM7964 Bma-grk-2; Uncharacterized protein K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
B Other
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ASerine/threonine kinases: CAMK group
B CAMK1 family [OT]
C BM_BM4856 Bma-cmk-1; Cam kinase protein 1, putative K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
B CAMK2 family
B CAMKL family
C BM_BM3380 Bma-sad-1; uncharacterized protein K08796 BRSK; BR serine/threonine kinase [EC:2.7.11.1]
C BM_BM4697 Bma-par-1; Kinase associated domain 1 family protein K08798 MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
C BM_BM6168 Bma-pig-1; Uncharacterized protein K08799 MELK; maternal embryonic leucine zipper kinase [EC:2.7.11.1]
C BM_BM5465 Bma-aak-2; Uncharacterized protein K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
C BM_BM6930 Bma-par-4; Uncharacterized protein K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
B DAPK family
C BM_BM5018 Bma-dapk-1; Protein kinase domain containing protein K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
B DCAMKL family
C BM_BM7156 Bma-zyg-8; Doublecortin family protein K08805 DCLK1_2; doublecortin-like kinase 1/2 [EC:2.7.11.1]
B MAPKAPK family [OT]
C BM_BM5443 Bma-mnk-1; Protein kinase domain containing protein K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
B MLCK family
B PHK family
C BM_BM6708 Bm6708; Uncharacterized protein K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
B PIM family [OT]
B PKD family
C BM_BM6249 Bma-dkf-1; PRKD2 protein, putative K06070 PKD; protein kinase D [EC:2.7.11.13]
B PSK family
C BM_BM9769 Bm9769; Uncharacterized protein K08808 PSKH; protein serine kinase H [EC:2.7.11.1]
B RAD53 family
B Trio family [OT]
B TSSK family
C BM_BM10582 Bm10582; Protein kinase domain containing protein K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
C BM_BM6129 Bm6129; serine/threonine protein kinase, putative K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
B CDPK family
B CASK family
C BM_BM12412 Bma-lin-2; abnormal cell lineage protein 2, putative K06103 CASK; calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1]
B Trbl family
B Other
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ASerine/threonine kinases: CK1 group
B CK1 family [OT]
C BM_BM1931 Bma-kin-19; Uncharacterized protein K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
C BM_BM4148 Bma-kin-20; Uncharacterized protein K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
B TTBK family
C BM_BM2677 Bm2677; Protein kinase domain containing protein K08815 TTBK; tau tubulin kinase [EC:2.7.11.26]
B VRK family
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ASerine/threonine kinases: CMGC group
B CDK family
C BM_BM4613 Bma-dyf-18; Uncharacterized protein K08817 CCRK; cell cycle related kinase [EC:2.7.11.22]
C BM_BM1826 Bm1826; Protein kinase domain containing protein K08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]
C BM_BM5591 Bma-cdk-1; cell division control protein 2 homolog, putative K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
C BM_BM10150 Bm10150; cell division control protein 2 homolog, putative K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
C BM_BM4787 Bm4787; cell division control protein 2 homolog, putative K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
C BM_BM10147 Bm10147; cell division control protein 2 homolog, putative K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
C BM_BM10326 Bm10326; Protein kinase domain containing protein K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
C BM_BM9253 Bma-cdk-2; Cell division protein kinase 2, putative K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
C BM_BM6048 Bma-cdk-5; Protein kinase domain containing protein K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
C BM_BM13749 Bma-cdk-7.2; cyclin-dependent kinase 7 homolog, putative K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
C BM_BM3948 Bma-cdk-8; Uncharacterized protein K02208 CDK8_11; cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23]
C BM_BM4679 Bma-cdk-9; cyclin-dependent kinase 9, putative K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
C BM_BM11420 Bm11420; cell division protein kinase 10, putative K02449 CDK10; cyclin-dependent kinase 10 [EC:2.7.11.22]
C BM_BM7352 Bm7352; uncharacterized protein K08821 CDK14; cyclin-dependent kinase 14 [EC:2.7.11.22]
C BM_BM2050 Bma-pct-1; Uncharacterized protein K15595 CDK17; cyclin-dependent kinase 17 [EC:2.7.11.22]
B MAPK family [OT]
C BM_BM4047 Bma-mpk-1; Uncharacterized protein K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
C BM_BM9350 Bm9350; Uncharacterized protein K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
C BM_BM1820 Bma-jnk-1; Uncharacterized protein K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
C BM_BM1712 Bma-pmk-1; P38 map kinase family protein 2, isoform b, putative K04441 P38; p38 MAP kinase [EC:2.7.11.24]
C BM_BM4029 Bma-pmk-3; Mitogen-activated protein kinase, putative K04441 P38; p38 MAP kinase [EC:2.7.11.24]
C BM_BM6215 Bma-lit-1; MGC81364 protein, putative K04468 NLK; nemo like kinase [EC:2.7.11.24]
B GSK family [OT]
C BM_BM17519 Bm17519; Uncharacterized protein K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
C BM_BM6312 Bm6312; Uncharacterized protein K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
B CLK family
C BM_BM3102 Bma-madd-3; Uncharacterized protein K08823 CLK2_3; dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
B CDKL family
C BM_BM6528 Bma-cdkl-1; serine/threonine-protein kinase, putative K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
B DYRK family [OT]
C BM_BM5542 Bma-mbk-1; Uncharacterized protein K08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]
C BM_BM4232 Bma-mbk-2; Uncharacterized protein K18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]
C BM_BM3519 Bma-prpf-4; Protein kinase domain containing protein K08827 PRPF4B; serine/threonine-protein kinase PRP4 [EC:2.7.11.1]
B RCK family [OT]
C BM_BM9760 Bma-dyf-5; Uncharacterized protein K08829 MAK; male germ cell-associated kinase [EC:2.7.11.22]
B SRPK family [OT]
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ASerine/threonine kinases: STE group
B STE7 family
C BM_BM6799 Bma-mek-2; Uncharacterized protein K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
C BM_BM4039 Bm4039; Serine/threonine-protein kinase F42G10.2, putative K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
C BM_BM9351 Bma-sek-3; Protein kinase domain containing protein K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
B STE20 family
C BM_BM7400 Bma-mig-15; Uncharacterized protein K08840 TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]
C BM_BM6934 Bma-gck-3; oxidative-stress responsive 1, putative K08835 OXSR1; serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1]
C BM_BM1943 Bma-gck-4; Protein kinase domain containing protein K08836 SLK; STE20-like kinase [EC:2.7.11.1]
C BM_BM6742 Bma-strd-1; Uncharacterized protein K08271 STRADA; STE20-related kinase adapter protein alpha
C BM_BM3378 Bm3378; Uncharacterized protein K04412 STK3; serine/threonine kinase 3
C BM_BM5826 Bma-gck-1; Germinal center kinase family protein 1, putative K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
B STE11 family
C BM_BM5676 Bm5676; Protein kinase domain containing protein K04420 MAP3K2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
C BM_BM6488 Bma-mtk-1; Uncharacterized protein K04428 MAP3K4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
C BM_BM12235 Bma-nsy-1; Neuronal symmetry protein 1, putative K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
B Other
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ASerine/threonine kinases: TKL group
B IRAK family
C BM_BM4945 Bma-pik-1; Uncharacterized protein K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
B LISK family [OT]
B LRRK family
B MLK family
C BM_BM9342 Bm9342; Protein kinase domain containing protein K04417 MAP3K9; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
C BM_BM2331 Bm2331; Protein kinase domain containing protein K17535 TNNI3K; serine/threonine-protein kinase TNNI3K [EC:2.7.11.1]
C BM_BM2471 Bma-pat-4; integrin-linked kinase, putative K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
B RAF family [OT]
C BM_BM7093 Bma-lin-45; Uncharacterized protein K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
B RIPK family [OT]
B Other
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ASerine/threonine kinases: Other
B RGC family [OT]
C BM_BM5449 Bma-gcy-28; Uncharacterized protein K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
B BUB family
B Bud32 family
C BM_BM4255 Bm4255; Uncharacterized protein K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
B CAMKK family
B CDC7 family
C BM_BM8839 Bma-cdc-7; Protein kinase domain containing protein K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
B CK2 family
C BM_BM1705 Bma-kin-3; Uncharacterized protein K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
B Haspin family
C BM_BM1899 Bm1899; GSG2, putative K16315 GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
B IKK family [OT]
C BM_BM9065 Bm9065; Protein kinase domain containing protein K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
B IRE family
B MOS family
C BM_BM9297 Bm9297; Protein kinase domain containing protein K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
B NAK family [OT]
C BM_BM12590 Bma-sel-5; uncharacterized protein K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
C BM_BM12611 Bma-gakh-1; Uncharacterized protein K08855 GAK; cyclin G-associated kinase [EC:2.7.11.1]
C BM_BM8678 Bm8678; Protein kinase domain containing protein K08856 STK16; serine/threonine kinase 16 [EC:2.7.11.1]
B NEK family
C BM_BM3452 Bma-nekl-3; Serine/threonine-protein kinase Nek7, putative K20876 NEK7; serine/threonine-protein kinase Nek7 [EC:2.7.11.34]
B NKF1 family
B NKF2 family
C BM_BM3116 Bma-pink-1; Protein kinase domain containing protein K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
B NKF3 family
B NKF4 family
B NKF5 family
B NRBP family
C BM_BM4692 Bma-hpo-11; Uncharacterized protein K08875 NRBP; nuclear receptor-binding protein
B PEK family [OT]
C BM_BM7162 Bma-gcn-2; Uncharacterized protein K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
B PLK family [OT]
C BM_BM7046 Bm7046; serine/threonine-protein kinase plk-2, putative K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
C BM_BM8857 Bm8857; Protein kinase domain containing protein K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
B SCY1 family [OT]
C BM_BM9111 Bm9111; Protein kinase domain containing protein K17541 SCYL2; SCY1-like protein 2
B Slob family
C BM_BM10845 Bm10845; Uncharacterized protein K17543 PXK; PX domain-containing protein kinase-like protein
B TBCK family
B TLK family
C BM_BM2037 Bma-tlk-1; Uncharacterized protein K08864 TLK; tousled-like kinase [EC:2.7.11.1]
B TOPK family
B TTK family
B ULK family [OT]
C BM_BM6939 Bma-unc-51; Uncharacterized protein K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
C BM_BM9610 Bm9610; Uncharacterized protein K21358 ULK3; serine/threonine-protein kinase ULK3 [EC:2.7.11.1]
B VPS15 family
C BM_BM7590 Bma-vps-15; Protein kinase domain containing protein K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
B WEE family
B Wnk family
C BM_BM2789 Bma-wnk-1; Protein kinase domain containing protein K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
B ABC1 family
C BM_BM2616 Bma-coq-8; chaperone-activity of bc1 complex-like, mitochondrial, putative K08869 ADCK; aarF domain-containing kinase
C BM_BM11278 Bm11278; Uncharacterized protein K08869 ADCK; aarF domain-containing kinase
C BM_BM13822 Bm13822; ABC1 family protein K08869 ADCK; aarF domain-containing kinase
B Alpha family [OT]
C BM_BM4019 Bma-efk-1; MHCK/EF2 kinase domain family protein K08292 EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
B BCR family
B BRD family [OT]
B FAST family
B G11 family
B H11 family
B PDHK family [OT]
C BM_BM13766 Bma-pdhk-2; kinase, mitochondrial precursor, putative K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
B PIKK family [OT]
C BM_BM5618 Bma-atl-1; Phosphatidylinositol 3- and 4-kinase family protein K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
C BM_BM1727 Bm1727; Uncharacterized protein K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
C BM_BM2810 Bma-trr-1; Uncharacterized protein K08874 TRRAP; transformation/transcription domain-associated protein
B RIO family [OT]
C BM_BM7248 Bma-riok-2; RIO1 family protein K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
C BM_BM7506 Bma-riok-3; RIO1 family protein K08872 RIOK3; RIO kinase 3 [EC:2.7.11.1]
B TAF1 family
C BM_BM11123 Bma-taf-1; Uncharacterized protein K03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
B TIF1 family [OT]
C BM_BM9671 Bm9671; Uncharacterized protein K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
B Other
C BM_BM7655 Bma-dcaf-1; Uncharacterized protein K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
B Bacterial family
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AReceptor serine/threonine kinases (RSTK): TKL group
B TGFBR1 family [OT]
C BM_BM2507 Bma-sma-6; Protein kinase domain containing protein K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
C BM_BM12004 Bma-daf-1; Uncharacterized protein K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
B TGFBR2 family [OT]
C BM_BM3941 Bma-unc-129; Uncharacterized protein K04669 TGFBRX; TGF-beta receptor, other
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AReceptor tyrosine kinases (RTK)
B EGFR family [OT]
C BM_BM7615 Bma-let-23; Uncharacterized protein K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
B INSR family [OT]
B PDGFR family [OT]
B FGFR family [OT]
B VEGFR family [OT]
C BM_BM5314 Bm5314; Uncharacterized protein K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
B MET family
C BM_BM5789 Bma-svh-2; Uncharacterized protein K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
B TRK family [OT]
B EPH family [OT]
C BM_BM5071 Bma-vab-1; ephrin receptor 1 precursor, putative K05110 EPHB1; Eph receptor B1 [EC:2.7.10.1]
B AXL family
B ALK family
C BM_BM5720 Bma-scd-2; Uncharacterized protein K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
B TIE family
B ROR family
B DDR family
C BM_BM3311 Bma-ddr-2; Protein kinase domain containing protein K05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]
B RET family
B ROS family
B CCK family
B RYK family
B MUSK family
B LMR family [OT]
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ANon-receptor tyrosine kinases
B ABL family
C BM_BM5124 Bma-abl-1; Tyrosine-protein kinase abl-1, putative K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
B ACK family
B CSK family
C BM_BM6666 Bma-csk-1; C-terminal src kinase protein 1, putative K05728 CSK; c-src tyrosine kinase [EC:2.7.10.2]
B FAK family
B FES family
C BM_BM3119 Bm3119; Protein kinase domain containing protein K08889 FER; tyrosine-protein kinase Fer [EC:2.7.10.2]
C BM_BM7313 Bm7313; Uncharacterized protein K08889 FER; tyrosine-protein kinase Fer [EC:2.7.10.2]
B JAK family [OT]
B SRC family
C BM_BM7182 Bma-src-1; SRC-1, putative K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
B TEC family
B SYK family
B Other
B Bacterial
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AHistidine kinases
B OmpR family
B NarL family
B Spo family [OT]
B CitB family [OT]
B LytTR family [OT]
B NtrC family
B CheA family [OT]
B Cell cycle family [OT]
B Lux family [OT]
B LuxR family [OT]
B Other
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 2, 2024
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Classification taken and modified from Hanks (2003)