+D Chaperone KO
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Chaperones and Folding Catalysts - Bombus terrestris (buff-tailed bumblebee)
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AHeat shock proteins
B HSP110
C 100646893 heat shock 70 kDa protein 4 isoform X1 K09485 HSP110; heat shock protein 110kDa
C 100642850 LOW QUALITY PROTEIN: hypoxia up-regulated protein 1 K09486 HYOU1; hypoxia up-regulated 1
B HSP100
C 100647011 caseinolytic peptidase B protein homolog K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
C 100647048 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial isoform X1 K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
B HSP90
C 100645819 heat shock protein 83 K04079 HSP90A; molecular chaperone HtpG
C 100645524 heat shock protein 83 K04079 HSP90A; molecular chaperone HtpG
C 100649277 LOW QUALITY PROTEIN: endoplasmin K09487 HSP90B; heat shock protein 90kDa beta
C 100648632 heat shock protein 75 kDa, mitochondrial K09488 TRAP1; TNF receptor-associated protein 1
B HSP70 / DNAK
C 100650203 heat shock 70 kDa protein cognate 4 isoform X1 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 100645451 heat shock 70 kDa protein cognate 4 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 100644229 LOW QUALITY PROTEIN: heat shock 70 kDa protein cognate 4 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 100644048 LOW QUALITY PROTEIN: heat shock 70 kDa protein cognate 5 K04043 dnaK; molecular chaperone DnaK
B HSP60 / Chaperonin
C 100646058 T-complex protein 1 subunit alpha K09493 CCT1; T-complex protein 1 subunit alpha
C 100649498 T-complex protein 1 subunit beta K09494 CCT2; T-complex protein 1 subunit beta
C 100652074 T-complex protein 1 subunit gamma K09495 CCT3; T-complex protein 1 subunit gamma
C 100642585 T-complex protein 1 subunit delta K09496 CCT4; T-complex protein 1 subunit delta
C 100644778 T-complex protein 1 subunit epsilon K09497 CCT5; T-complex protein 1 subunit epsilon
C 100652196 T-complex protein 1 subunit zeta K09498 CCT6; T-complex protein 1 subunit zeta
C 100649377 T-complex protein 1 subunit eta K09499 CCT7; T-complex protein 1 subunit eta
C 100645354 T-complex protein 1 subunit theta K09500 CCT8; T-complex protein 1 subunit theta
C 100644817 LOW QUALITY PROTEIN: 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
B HSP47
B HSP40 / DNAJ
C 100645708 dnaJ homolog subfamily A member 1 K09502 DNAJA1; DnaJ homolog subfamily A member 1
C 100650817 protein tumorous imaginal discs, mitochondrial isoform X1 K09504 DNAJA3; DnaJ homolog subfamily A member 3
C 100650629 dnaJ homolog subfamily C member 21 K09506 DNAJA5; DnaJ homolog subfamily A member 5
C 100645002 dnaJ protein homolog 1 K09507 DNAJB1; DnaJ homolog subfamily B member 1
C 100650705 dnaJ homolog subfamily B member 6 K09512 DNAJB6; DnaJ homolog subfamily B member 6
C 100648149 dnaJ homolog subfamily B member 6 K09512 DNAJB6; DnaJ homolog subfamily B member 6
C 100652165 dnaJ homolog shv K09517 DNAJB11; DnaJ homolog subfamily B member 11
C 100648038 dnaJ homolog subfamily B member 12 isoform X1 K09518 DNAJB12; DnaJ homolog subfamily B member 12
C 100648574 LOW QUALITY PROTEIN: dnaJ homolog subfamily B member 13-like K09519 DNAJB13; DnaJ homolog subfamily B member 13
C 100651703 dnaJ homolog subfamily C member 1 K09521 DNAJC1; DnaJ homolog subfamily C member 1
C 100649201 dnaJ homolog subfamily C member 2 isoform X1 K09522 DNAJC2; DnaJ homolog subfamily C member 2
C 100650289 dnaJ homolog subfamily C member 3 K09523 DNAJC3; DnaJ homolog subfamily C member 3
C 100650974 dnaJ homolog subfamily C member 5 isoform X1 K09525 DNAJC5; DnaJ homolog subfamily C member 5
C 100651622 LOW QUALITY PROTEIN: dnaJ homolog subfamily C member 7 K09527 DNAJC7; DnaJ homolog subfamily C member 7
C 100651705 dnaJ homolog subfamily C member 8 K09528 DNAJC8; DnaJ homolog subfamily C member 8
C 100649429 dnaJ homolog subfamily C member 9 isoform X2 K09529 DNAJC9; DnaJ homolog subfamily C member 9
C 100642273 dnaJ homolog subfamily C member 11 isoform X1 K09531 DNAJC11; DnaJ homolog subfamily C member 11
C 100645606 J domain-containing protein isoform X1 K09532 DNAJC12; DnaJ homolog subfamily C member 12
C 100643888 dnaJ homolog subfamily C member 13 isoform X2 K09533 DNAJC13; DnaJ homolog subfamily C member 13
C 100651714 dnaJ homolog dnj-5 K09534 DNAJC14; DnaJ homolog subfamily C member 14
C 100647075 dnaJ homolog subfamily C member 16 K09536 DNAJC16; DnaJ homolog subfamily C member 16
C 100648595 dnaJ homolog subfamily C member 17 K09537 DNAJC17; DnaJ homolog subfamily C member 17
C 100645320 mitochondrial import inner membrane translocase subunit TIM14 K09539 DNAJC19; DnaJ homolog subfamily C member 19
C 100645446 dnaJ homolog subfamily C member 22 K19370 DNAJC22; DnaJ homolog subfamily C member 22
C 100652104 translocation protein SEC63 homolog K09540 SEC63; translocation protein SEC63
C 100649527 dnaJ homolog subfamily C member 28 isoform X2 K19373 DNAJC28; DnaJ homolog subfamily C member 28
C 100645838 chaperone protein dnaJ 1, mitochondrial K19374 DNAJC30; DnaJ homolog subfamily C member 30
C 100646890 iron-sulfur cluster co-chaperone protein HscB, mitochondrial K04082 hscB; molecular chaperone HscB
B HSP33
B HSP24
C 100643466 grpE protein homolog, mitochondrial K03687 GRPE; molecular chaperone GrpE
B HSP20
C 100652068 protein lethal(2)essential for life K09542 CRYAB; crystallin, alpha B
C 105666322 protein lethal(2)essential for life K09542 CRYAB; crystallin, alpha B
C 105667104 protein lethal(2)essential for life K09542 CRYAB; crystallin, alpha B
C 100651433 protein lethal(2)essential for life K09542 CRYAB; crystallin, alpha B
C 100649836 LOW QUALITY PROTEIN: protein lethal(2)essential for life K09542 CRYAB; crystallin, alpha B
C 105666325 protein lethal(2)essential for life K09542 CRYAB; crystallin, alpha B
B HSP15
B HSP10
C 100646003 10 kDa heat shock protein, mitochondrial K04078 groES; chaperonin GroES
B GimC
C 100650223 prefoldin subunit 1 K09548 PFDN1; prefoldin subunit 1
C 100646096 probable prefoldin subunit 2 K09549 PFDN2; prefoldin subunit 2
C 100643766 prefoldin subunit 4 K09550 PFDN4; prefoldin subunit 4
C 100646113 prefoldin subunit 5 K04797 pfdA; prefoldin alpha subunit
C 100651503 prefoldin subunit 6 K04798 pfdB; prefoldin beta subunit
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AOther chaperones and cochaperones
B Calnexin / calreticulin
C 100643471 calnexin isoform X1 K08054 CANX; calnexin
C 100643307 calreticulin K08057 CALR; calreticulin
B DegP / HtrA
C 100651265 LOW QUALITY PROTEIN: serine protease HTRA2, mitochondrial K08669 HTRA2; HtrA serine peptidase 2 [EC:3.4.21.108]
B AAA proteases
C 100647264 paraplegin K09552 SPG7; spastic paraplegia 7 [EC:3.4.24.-]
C 100643893 LOW QUALITY PROTEIN: AFG3-like protein 2 K08956 AFG3; AFG3 family protein [EC:3.4.24.-]
B PapD
B SecB
B Sti1 / p60
C 105665611 stress-induced-phosphoprotein 1 K09553 STIP1; stress-induced-phosphoprotein 1
B Cdc37 / p50
C 100647650 LOW QUALITY PROTEIN: hsp90 co-chaperone Cdc37 K09554 CDC37; cell division cycle protein 37
B BAG
C 100645375 BAG family molecular chaperone regulator 2 K09556 BAG2; BCL2-associated athanogene 2
B Others
C 100650201 putative protein FAM10A4 K09560 ST13; suppressor of tumorigenicity protein 13
C 100644803 E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 100650822 hsp70-binding protein 1 isoform X1 K09562 HSPBP1; hsp70-interacting protein
C 100643321 HSPB1-associated protein 1 K19375 HSPBAP1; HSPB1-associated protein 1
C 100643222 protein OPI10 homolog isoform X2 K23327 HIKESHI; protein Hikeshi
C 100646105 cysteine and histidine-rich domain-containing protein K16729 CHORDC1; cysteine and histidine-rich domain-containing protein
C 100650141 prolyl 3-hydroxylase 1 isoform X2 K08134 P3H1; procollagen-proline 3-dioxygenase 1 [EC:1.14.11.7]
C 100644774 methyltransferase-like protein 23 K23151 METTL23; methyltransferase-like protein 23 [EC:2.1.1.-]
C 100649226 LOW QUALITY PROTEIN: protein unc-45 homolog B K21991 UNC45; protein unc-45
C 100651816 protein canopy 4 K22816 CNPY3_4; protein canopy 3/4
C 100651193 torsin-1A isoform X1 K22990 TOR1; torsin-1
C 100651232 SPARC K24262 SPARC; secreted protein acidic and rich in cysteine
C 100649012 small glutamine-rich tetratricopeptide repeat-containing protein alpha isoform X2 K16365 SGTA; small glutamine-rich tetratricopeptide repeat-containing protein alpha
C 100651329 tetratricopeptide repeat protein 1 K24926 TTC1; tetratricopeptide repeat protein 1
C 100642518 tetratricopeptide repeat protein 4 K24927 TTC4; tetratricopeptide repeat protein 4
C 100646314 LOW QUALITY PROTEIN: coiled-coil domain-containing protein 47 K24962 CCDC47; PAT complex subunit CCDC47
C 100644031 protein Asterix K24963 WDR83OS; PAT complex subunit Asterix
C 100644259 LDLR chaperone boca K25366 MESD; LRP chaperone MESD
C 100650066 uncharacterized protein LOC100650066 K26164 RIC3; protein RIC-3
C 100649276 activator of 90 kDa heat shock protein ATPase homolog 1 K26216 AHSA1; activator of Hsp90 ATPase protein 1
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AIntramolecular chaperones
B Subtilisin family
C 100643281 membrane-bound transcription factor site-1 protease K08653 MBTPS1; membrane-bound transcription factor site-1 protease [EC:3.4.21.112]
C 100650142 furin-like protease 1, isoforms 1/1-X/2 isoform X1 K01349 FURIN; furin [EC:3.4.21.75]
C 100648653 neuroendocrine convertase 1 isoform X1 K01359 PCSK1; proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93]
C 100643887 LOW QUALITY PROTEIN: neuroendocrine convertase 2 K01360 PCSK2; proprotein convertase subtilisin/kexin type 2 [EC:3.4.21.94]
C 100644491 furin-like protease 2 isoform X2 K08654 PCSK5; proprotein convertase subtilisin/kexin type 5 [EC:3.4.21.-]
C 100647107 LOW QUALITY PROTEIN: tripeptidyl-peptidase 2 K01280 TPP2; tripeptidyl-peptidase II [EC:3.4.14.10]
B Papain family
C 100645780 cathepsin L K01365 CTSL; cathepsin L [EC:3.4.22.15]
B Other peptidases
B Others
C 100649144 beta-hexosaminidase subunit beta K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 100647854 chitooligosaccharidolytic beta-N-acetylglucosaminidase K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
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AProtein folding catalysts
B Peptidyl prolyl isomerase
C Cyclophilin
D 100644681 LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase 5 K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 100644575 peptidyl-prolyl cis-trans isomerase 6 K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 100648851 peptidyl-prolyl cis-trans isomerase D K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
D 100651608 LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase E K09564 PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]
D 100651902 peptidyl-prolyl cis-trans isomerase K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
D 100642511 peptidyl-prolyl cis-trans isomerase K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
D 100647376 peptidyl-prolyl cis-trans isomerase cyp11 isoform X2 K09566 PPIG; peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8]
D 100645587 peptidyl-prolyl cis-trans isomerase H K09567 PPIH; peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]
D 100651615 LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase-like 1 K12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]
D 100647575 peptidyl-prolyl cis-trans isomerase-like 2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
D 100649526 peptidyl-prolyl cis-trans isomerase-like 3 K12734 PPIL3; peptidyl-prolyl cis-trans isomerase-like 3 [EC:5.2.1.8]
D 100651845 peptidyl-prolyl cis-trans isomerase sig-7 K12735 PPIL4; peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8]
D 100651801 peptidyl-prolyl cis-trans isomerase-like 6 K12739 PPIL6; peptidyl-prolyl cis-trans isomerase-like 6 [EC:5.2.1.8]
D 105665718 uncharacterized protein LOC105665718 K12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]
D 100647021 peptidyl-prolyl cis-trans isomerase CWC27 homolog K12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]
D 100648946 LOW QUALITY PROTEIN: E3 SUMO-protein ligase RanBP2 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C FKBP
D 100643673 12 kDa FK506-binding protein K09568 FKBP1; FK506-binding protein 1 [EC:5.2.1.8]
D 100642713 FK506-binding protein 59 K09571 FKBP4_5; FK506-binding protein 4/5 [EC:5.2.1.8]
D 100648773 inactive peptidyl-prolyl cis-trans isomerase FKBP6 K09572 FKBP6; FK506-binding protein 6 [EC:5.2.1.8]
D 100644443 LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase FKBP8 K09574 FKBP8; FK506-binding protein 8 [EC:5.2.1.8]
D 100645079 FK506-binding protein 2 isoform X2 K09577 FKBP14; FK506-binding protein 14 [EC:5.2.1.8]
D 100643076 peptidyl-prolyl cis-trans isomerase FKBP62 K20097 FKBPL; FK506-binding protein-like
C Parvulin
D 100651164 putative peptidyl-prolyl cis-trans isomerase dodo K09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]
D 100646329 LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 K09579 PIN4; peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [EC:5.2.1.8]
B Protein disulfide isomerase
C 100643526 thioredoxin-2 K03671 TXN; thioredoxin
C 100646990 thioredoxin, mitochondrial K03671 TXN; thioredoxin
C 100644780 thioredoxin, mitochondrial K03671 TXN; thioredoxin
C 100644863 glutaredoxin-C4 K03676 grxC; glutaredoxin 3
C 100647666 glutaredoxin-related protein 5, mitochondrial K07390 grxD; monothiol glutaredoxin
C 100647144 LOW QUALITY PROTEIN: uncharacterized protein LOC100647144 K17479 GRXCR1; glutaredoxin domain-containing cysteine-rich protein 1
C 100651233 protein disulfide-isomerase K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
C 100648662 protein disulfide-isomerase A3 K08056 PDIA3; protein disulfide-isomerase A3 [EC:5.3.4.1]
C 100652249 protein disulfide-isomerase A6 homolog K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C 100649717 thioredoxin domain-containing protein 5 homolog K13984 TXNDC5; thioredoxin domain-containing protein 5 [EC:5.3.4.1]
C 100643677 protein disulfide-isomerase TMX3 K09585 TMX3; protein disulfide-isomerase [EC:5.3.4.1]
C 100650350 cysteine-rich with EGF-like domain protein 2 K24335 CRELD; protein disulfide-isomerase [EC:5.3.4.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: January 25, 2024