+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Clostridium botulinum A3 Loch Maree</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
D      Cap binding complex
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
D      Pre-mRNA cleavage factor IIm (CFIIm)
D      Cleavage and polyadenylation specificity factor (CPSF) complex
D      Cleavage stimulation factor (CSTF) complex
D      U7-dependent histone pre-mRNA processing factors
D      DRB sensitivity inducing factor (DSIF) complex
D      N6-methyltransferase complex
D      Poly(A) addition factors
D      Negative regulators of mRNA 3' end processing
C    Other processing factors
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
D      TREX complex
D      TREX-2 complex
D      Nuclear pore complex
D      Ran-mediated transport factors
D      eIF4F and regulatory proteins
D      APOBEC1-ACF complex
D      Other transport factors
C    Surveillance factors
D      Surveillance complex
D      Protein phosphatase 2A
D      Other surveillance factors
C    Factors involved in mRNA localization
D      Cargo complex
D      Factors that have mRNA localization signals
D      Trans-acting binding proteins
D      Other mRNA localization factors
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
D      P-body specific factors
D      Stress granule specific factors
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
D      Lsm complex
D      5' exonucleases
D      Other 5'-3' decay factors
C    3'-5' decay
D      Core exosome factors
D      Exosome cofactors
D      TRAMP complex
D      Ski complex
D      Ccr4-NOT complex
D      Pan complex
D      Other 3'-5' decay factors
C    Other degradation factors
D      RNases
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A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        CLK_2374 ribonuclease, Rne/Rng family	K08301 rng; ribonuclease G [EC:3.1.26.-] 
E        CLK_1831 rnc; ribonuclease III	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        CLK_1944 RNA-metabolizing metallo-beta-lactamase family protein	K12574 rnj; ribonuclease J [EC:3.1.-.-] 
E        CLK_0736 RNA-metabolising metallo-beta-lactamase	K12574 rnj; ribonuclease J [EC:3.1.-.-] 
E        CLK_1779 HDIG/HD/KH domain protein	K18682 rny; ribonucrease Y [EC:3.1.-.-] 
E        CLK_3414 rnr; ribonuclease R	K12573 rnr; ribonuclease R [EC:3.1.13.1] 
E        CLK_2604 HDIG domain protein	K03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-] 
E        CLK_A0006 CMP-binding-factor 1	K03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-] 
D      Helicases
E        CLK_0036 rhlE; ATP-dependent RNA helicase RhlE	K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] 
E        CLK_2189 ATP-dependent RNA helicase, DEAD/DEAH box family	K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] 
E        CLK_1162 dbpA; ATP-dependent RNA helicase DbpA	K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] 
E        CLK_1160 ATP-dependent RNA helicase, DEAD/DEAH box family	K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] 
E        CLK_1464 ATP-dependent RNA helicase, DEAD/DEAH box family	K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] 
E        CLK_0440 recQ; ATP-dependent DNA helicase RecQ	K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] 
D      Other RNA degradosome components
E        CLK_3412 eno; phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        CLK_1788 pnpA; polyribonucleotide nucleotidyltransferase	K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 
E        CLK_3309 rho; transcription termination factor Rho	K03628 rho; transcription termination factor Rho 
E        CLK_2805 pfkA; 6-phosphofructokinase	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        CLK_2344 dnaK; chaperone protein DnaK	K04043 dnaK; molecular chaperone DnaK 
E        CLK_2714 groL; chaperonin GroEL	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
E        CLK_1178 hfq; RNA chaperone Hfq	K03666 hfq; host factor-I protein 
D      Others
E        CLK_2122 csrA; carbon storage regulator	K03563 csrA; carbon storage regulator 
E        CLK_2809 conserved hypothetical protein	K06958 rapZ; RNase adapter protein RapZ 
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
D      Cofactors
D      Others
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#Last updated: April 25, 2024