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Transfer RNA Biogenesis - Corvus cornix (hooded crow)
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
D 104692728 POP1; ribonucleases P/MRP protein subunit POP1 K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D 104687437 POP4; ribonuclease P protein subunit p29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D 104688757 POP5; ribonuclease P/MRP protein subunit POP5 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D 104697924 RPP30; ribonuclease P protein subunit p30 isoform X1 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D 104683498 RPP14; ribonuclease P protein subunit p14 K14529 RPP14; ribonuclease P protein subunit RPP14 [EC:3.1.26.5]
D 104686555 RPP25L; ribonuclease P protein subunit p25-like protein K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 104697441 RPP25; ribonuclease P protein subunit p25 K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 104689203 RPP38; ribonuclease P protein subunit p38 K14523 RPP38; ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5]
D 104696793 RPP40; ribonuclease P protein subunit p40 K14530 RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D 104686786 ELAC1; LOW QUALITY PROTEIN: zinc phosphodiesterase ELAC protein 1 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 104695630 LOW QUALITY PROTEIN: zinc phosphodiesterase ELAC protein 2 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 120410974 LOW QUALITY PROTEIN: zinc phosphodiesterase ELAC protein 2-like K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 104684341 RNASET2; ribonuclease T2 K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
D 104684793 pentatricopeptide repeat-containing protein 1, mitochondrial K17710 PTCD1; pentatricopeptide repeat domain-containing protein 1
C CCA adding factors
D 104683386 TRNT1; CCA tRNA nucleotidyltransferase 1, mitochondrial K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
D 104695744 TSEN2; tRNA-splicing endonuclease subunit Sen2 isoform X1 K15322 TSEN2; tRNA-splicing endonuclease subunit Sen2 [EC:4.6.1.16]
D 104693616 TSEN15; tRNA-splicing endonuclease subunit Sen15 K15324 TSEN15; tRNA-splicing endonuclease subunit Sen15
D 104694315 TSEN54; LOW QUALITY PROTEIN: tRNA-splicing endonuclease subunit Sen54 K15326 TSEN54; tRNA-splicing endonuclease subunit Sen54
C tRNA splicing ligase complex
D 104696258 RTCB; RNA-splicing ligase RtcB homolog K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D 104686081 C1H2orf49; ashwin K15432 ASW; ashwin
D 104695932 RTRAF; RNA transcription, translation and transport factor protein K15433 CGI99; RLL motif containing protein 1
D 104684274 FAM98B; protein FAM98B K15434 FAM98B; protein FAM98B
D 104685428 DDX1; ATP-dependent RNA helicase DDX1 K13177 DDX1; ATP-dependent RNA helicase DDX1 [EC:5.6.2.7]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
D 104688747 RAN; GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
D 104698355 XPOT; exportin-T isoform X1 K14288 XPOT; exportin-T
D 104691510 XPO1; exportin-1 K14290 XPO1; exportin-1
D 104684465 XPO5; exportin-5 isoform X5 K14289 XPO5; exportin-5
D 104687662 EEF1A2; elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
D 104692977 EEF1A1; elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
D 104696327 GTPBP1; GTP-binding protein 1 isoform X3 K24887 GTPBP1; GTP-binding protein 1
C tRNA import factors
D 120411901 TNPO3; transportin-3 K15436 TRPO3; transportin-3
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D 104685624 EPRS1; bifunctional glutamate/proline--tRNA ligase isoform X1 K14163 EPRS; bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]
D 104684983 EARS2; probable glutamate--tRNA ligase, mitochondrial isoform X1 K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D 104695512 PARS2; probable proline--tRNA ligase, mitochondrial isoform X1 K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D 104695755 IARS1; isoleucine--tRNA ligase, cytoplasmic isoform X2 K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 104685738 IARS2; isoleucine--tRNA ligase, mitochondrial K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 104688969 LARS2; probable leucine--tRNA ligase, mitochondrial isoform X2 K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 104689630 LARS1; leucine--tRNA ligase, cytoplasmic K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 104691697 MARS2; methionine--tRNA ligase, mitochondrial K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 104683491 QARS1; glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D 104692400 RARS2; probable arginine--tRNA ligase, mitochondrial isoform X1 K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 104693564 RARS1; arginine--tRNA ligase, cytoplasmic isoform X1 K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 104691965 KARS1; lysine--tRNA ligase isoform X1 K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D 104694076 DARS1; aspartate--tRNA ligase, cytoplasmic K22503 DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 104695616 DARS2; aspartate--tRNA ligase, mitochondrial isoform X1 K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 104697114 AIMP1; aminoacyl tRNA synthase complex-interacting multifunctional protein 1 K15437 AIMP1; aminoacyl tRNA synthase complex-interacting multifunctional protein 1
D 104685050 AIMP2; aminoacyl tRNA synthase complex-interacting multifunctional protein 2 K15438 AIMP2; aminoacyl tRNA synthase complex-interacting multifunctional protein 2
D 104691451 EEF1E1; eukaryotic translation elongation factor 1 epsilon-1 K15439 EEF1E1; eukaryotic translation elongation factor 1 epsilon-1
C Other AARSs
D 104684417 AARS2; alanine--tRNA ligase, mitochondrial isoform X1 K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 104691769 AARS1; alanine--tRNA ligase, cytoplasmic K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 104690300 NARS2; probable asparagine--tRNA ligase, mitochondrial isoform X3 K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 104698612 NARS1; asparagine--tRNA ligase, cytoplasmic K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 104686501 GARS1; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D 104686593 TARS1; threonine--tRNA ligase 1, cytoplasmic isoform X1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 104684032 TARS3; threonine--tRNA ligase 2, cytoplasmic K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 104692475 SARS1; serine--tRNA ligase, cytoplasmic isoform X1 K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 104686323 CARS2; probable cysteine--tRNA ligase, mitochondrial isoform X2 K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 104687953 CARS1; cysteine--tRNA ligase, cytoplasmic isoform X1 K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 104693512 histidine--tRNA ligase, cytoplasmic K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 104693553 histidine--tRNA ligase, cytoplasmic-like isoform X1 K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 104696805 FARS2; phenylalanine--tRNA ligase, mitochondrial isoform X1 K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 104693092 FARSB; phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D 104696205 YARS2; LOW QUALITY PROTEIN: tyrosine--tRNA ligase, mitochondrial K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 104686463 WARS1; tryptophan--tRNA ligase, cytoplasmic isoform X2 K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 104687103 WARS2; tryptophan--tRNA ligase, mitochondrial isoform X2 K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D 104685724 DTD1; D-aminoacyl-tRNA deacylase 1 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 104688402 DTD2; D-aminoacyl-tRNA deacylase 2 isoform X1 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 104697825 LOW QUALITY PROTEIN: alanyl-tRNA editing protein Aarsd1-like K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
C AARS associated factors
D 104697711 tRNA selenocysteine 1-associated protein 1 isoform X1 K25102 TRNAU1AP; tRNA selenocysteine 1-associated protein 1
D 104689809 HINT1; histidine triad nucleotide-binding protein 1 K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D 120411509 HINT2; histidine triad nucleotide-binding protein 2, mitochondrial K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D 104690834 HINT3; histidine triad nucleotide-binding protein 3 K12150 HINT3; adenosine 5'-monophosphoramidase HINT3 [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
D 104691867 ADAT1; tRNA-specific adenosine deaminase 1 isoform X1 K15440 TAD1; tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
D 104693833 ADAT2; tRNA-specific adenosine deaminase 2 K15441 TAD2; tRNA-specific adenosine deaminase 2 [EC:3.5.4.-]
C Dihydorouridine synthases
D 104698183 DUS1L; tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like isoform X1 K05542 DUS1; tRNA-dihydrouridine synthase 1 [EC:1.3.1.88]
D 104687479 DUS2; tRNA-dihydrouridine(20) synthase [NAD(P)+]-like K05543 DUS2; tRNA-dihydrouridine synthase 2 [EC:1.3.1.91]
D 104697413 DUS3L; tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like isoform X1 K05544 DUS3; tRNA-dihydrouridine synthase 3 [EC:1.3.1.89]
D 104686922 DUS4L; tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like isoform X1 K05545 DUS4; tRNA-dihydrouridine synthase 4 [EC:1.3.1.90]
C Methylthiotransferase
D 104691436 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase isoform X2 K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
C Methyltransferases
D 104688623 TRMT2A; tRNA (uracil-5-)-methyltransferase homolog A K15332 TRMT2A; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.-]
D 104691743 TRMT2B; LOW QUALITY PROTEIN: tRNA (uracil(54)-C(5))-methyltransferase homolog K15331 TRMT2B; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D 104684290 TARBP1; probable methyltransferase TARBP1 K15333 TRM3; tRNA guanosine-2'-O-methyltransferase [EC:2.1.1.34]
D 104685923 NSUN2; RNA cytosine C(5)-methyltransferase NSUN2 K15335 NSUN2; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.203]
D 104689434 NSUN3; tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial isoform X1 K21969 NSUN3; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.-]
D 104687308 TRMT5; tRNA (guanine(37)-N1)-methyltransferase isoform X2 K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D 104686819 TRMT61A; tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D 104685718 TRMT61B; tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial isoform X2 K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D 104696624 TRMT6; tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 isoform X2 K03256 TRM6; tRNA (adenine58-N1)-methyltransferase non-catalytic subunit
D 120412229 FTSJ1; LOW QUALITY PROTEIN: putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase K14864 FTSJ1; tRNA (cytidine32/guanosine34-2'-O)-methyltransferase [EC:2.1.1.205]
D 104698502 tRNA N(3)-methylcytidine methyltransferase METTL2 K24974 METTL2; tRNA N(3)-methylcytidine methyltransferase METTL2 [EC:2.1.1.-]
D 104689023 METTL6; tRNA N(3)-methylcytidine methyltransferase METTL6 isoform X1 K00599 METTL6; tRNA N(3)-methylcytidine methyltransferase METTL6 [EC:2.1.1.-]
D 104690049 ALKBH8; alkylated DNA repair protein alkB homolog 8 isoform X1 K10770 ALKBH8; alkylated DNA repair protein alkB homolog 8 [EC:1.14.11.- 2.1.1.229]
D 104697084 TRMT10A; tRNA methyltransferase 10 homolog A isoform X1 K15445 TRMT10; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]
D 104695846 TRMT10B; tRNA methyltransferase 10 homolog B isoform X1 K15445 TRMT10; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]
D 104690857 TRMT11; tRNA (guanine(10)-N2)-methyltransferase homolog K15430 TRM11; tRNA (guanine10-N2)-methyltransferase [EC:2.1.1.214]
D 104695571 TRMT13; tRNA:m(4)X modification enzyme TRM13 homolog K15446 TRM13; tRNA:m4X modification enzyme [EC:2.1.1.225]
D 104690762 TRMT44; LOW QUALITY PROTEIN: probable tRNA (uracil-O(2)-)-methyltransferase K15447 TRM44; tRNASer (uridine44-2'-O)-methyltransferase [EC:2.1.1.211]
D 104686362 WDR4; tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 K15443 TRM82; tRNA (guanine-N(7)-)-methyltransferase subunit TRM82
D 104689209 TRDMT1; tRNA (cytosine(38)-C(5))-methyltransferase isoform X1 K15336 TRDMT1; tRNA (cytosine38-C5)-methyltransferase [EC:2.1.1.204]
D 104695778 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1-like isoform X1 K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D 104691361 TRMT12; tRNA wybutosine-synthesizing protein 2 homolog isoform X1 K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D 104695482 TYW3; tRNA wybutosine-synthesizing protein 3 homolog K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
D 104698084 LCMT2; tRNA wybutosine-synthesizing protein 4 K15451 PPM2; tRNA wybutosine-synthesizing protein 4 [EC:2.1.1.290 2.3.1.231]
D 104694138 TYW5; tRNA wybutosine-synthesizing protein 5 K18066 TYW5; tRNA wybutosine-synthesizing protein 5 [EC:1.14.11.42]
C Psudouridine synthases
D 104688632 PUS1; tRNA pseudouridine synthase A isoform X2 K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D 104692215 PUS3; tRNA pseudouridine(38/39) synthase isoform X1 K01855 PUS3; tRNA pseudouridine38/39 synthase [EC:5.4.99.45]
D 104695024 TRUB1; probable tRNA pseudouridine synthase 1 isoform X1 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D 104686871 PUS7; pseudouridylate synthase 7 homolog isoform X1 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 104698326 PUS7L; pseudouridylate synthase 7 homolog-like protein isoform X1 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 104691507 PUS10; tRNA pseudouridine synthase Pus10 isoform X1 K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D 104692137 RPUSD4; mitochondrial RNA pseudouridine synthase RPUSD4 K22538 RPUSD4; mitochondrial RNA pseudouridine synthase RPUSD4 [EC:5.4.99.-]
C Thiolation factors
D 104686853 TRMU; mitochondrial tRNA-specific 2-thiouridylase 1 isoform X3 K21027 TRMU; tRNA-5-taurinomethyluridine 2-sulfurtransferase [EC:2.8.1.14]
D 104691926 CTU2; cytoplasmic tRNA 2-thiolation protein 2 K14169 CTU2; cytoplasmic tRNA 2-thiolation protein 2
D 104698041 NFS1; cysteine desulfurase, mitochondrial K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D 104688455 URM1; ubiquitin-related modifier 1 K12161 URM1; ubiquitin related modifier 1
D 104687787 MOCS3; adenylyltransferase and sulfurtransferase MOCS3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C KEOPS/EKC complex
D 104687740 TP53RK; EKC/KEOPS complex subunit TP53RK K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D 104693729 OSGEPL1; probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial isoform X1 K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D 104686911 TPRKB; EKC/KEOPS complex subunit TPRKB K15901 TPRKB; EKC/KEOPS complex subunit TPRKB/CGI121
D 120410062 GON7; EKC/KEOPS complex subunit GON7 K15903 GON7; EKC/KEOPS complex subunit GON7
C Elongator complex
D 104689792 ELP1; elongator complex protein 1 isoform X2 K11373 ELP1; elongator complex protein 1
D 104685905 ELP2; elongator complex protein 2 isoform X1 K11374 ELP2; elongator complex protein 2
D 104696895 ELP3; elongator complex protein 3 K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D 104686481 ELP6; elongator complex protein 6 K11377 ELP6; elongator complex protein 6
C Elongator related proteins
D 120409659 DPH3; DPH3 homolog isoform X1 K15455 DPH3; diphthamide biosynthesis protein 3
D 120410368 KTI12; protein KTI12 homolog K15456 KTI12; protein KTI12
C Other tRNA modification factors
D 104692979 MTO1; protein MTO1 homolog, mitochondrial isoform X1 K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D 104687065 QTRT2; queuine tRNA-ribosyltransferase accessory subunit 2 isoform X1 K15407 QTRT2; queuine tRNA-ribosyltransferase accessory subunit
D 104694496 SEPHS1; selenide, water dikinase 1 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 120412226 LOW QUALITY PROTEIN: selenide, water dikinase 2-like K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 104685061 THUMPD1; THUMP domain-containing protein 1 K06963 TAN1; tRNA acetyltransferase TAN1
D 104689676 THG1L; LOW QUALITY PROTEIN: probable tRNA(His) guanylyltransferase K10761 THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79]
D 104694657 ATE1; arginyl-tRNA--protein transferase 1 isoform X5 K00685 ATE1; arginyl-tRNA---protein transferase [EC:2.3.2.8]
D 104683494 DALRD3; DALR anticodon-binding domain-containing protein 3 K24973 DALRD3; DALR anticodon-binding domain-containing protein 3
B tRNA degradation factors
C TRAMP complex
D 104685871 TENT4A; terminal nucleotidyltransferase 4A isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
D 104687453 TENT4B; LOW QUALITY PROTEIN: terminal nucleotidyltransferase 4B K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
D 104695820 ZCCHC7; zinc finger CCHC domain-containing protein 7 isoform X1 K12597 AIR1_2; protein AIR1/2
D 104686770 MTREX; exosome RNA helicase MTR4 isoform X1 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
C Rapid tRNA decay (RTD) pathway factors
D 104693453 XRN1; 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
D 104691474 XRN2; 5'-3' exoribonuclease 2 isoform X1 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D 104685623 BPNT1; 3'(2'),5'-bisphosphate nucleotidase 1 K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
D 120409947 ribonuclease CL2-like K16631 ANG; angiogenin [EC:3.1.27.-]
D 104696486 interferon-induced protein with tetratricopeptide repeats 5-like K24850 IFIT5; interferon-induced protein with tetratricopeptide repeats 5
#
AProkaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D 104686786 ELAC1; LOW QUALITY PROTEIN: zinc phosphodiesterase ELAC protein 1 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 104695630 LOW QUALITY PROTEIN: zinc phosphodiesterase ELAC protein 2 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 120410974 LOW QUALITY PROTEIN: zinc phosphodiesterase ELAC protein 2-like K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 104684341 RNASET2; ribonuclease T2 K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D 104683386 TRNT1; CCA tRNA nucleotidyltransferase 1, mitochondrial K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D 104696258 RTCB; RNA-splicing ligase RtcB homolog K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D 104688969 LARS2; probable leucine--tRNA ligase, mitochondrial isoform X2 K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 104689630 LARS1; leucine--tRNA ligase, cytoplasmic K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 104695512 PARS2; probable proline--tRNA ligase, mitochondrial isoform X1 K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D 104696205 YARS2; LOW QUALITY PROTEIN: tyrosine--tRNA ligase, mitochondrial K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 104686463 WARS1; tryptophan--tRNA ligase, cytoplasmic isoform X2 K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 104687103 WARS2; tryptophan--tRNA ligase, mitochondrial isoform X2 K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 104686593 TARS1; threonine--tRNA ligase 1, cytoplasmic isoform X1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 104684032 TARS3; threonine--tRNA ligase 2, cytoplasmic K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 104695755 IARS1; isoleucine--tRNA ligase, cytoplasmic isoform X2 K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 104685738 IARS2; isoleucine--tRNA ligase, mitochondrial K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 104691965 KARS1; lysine--tRNA ligase isoform X1 K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D 104684417 AARS2; alanine--tRNA ligase, mitochondrial isoform X1 K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 104691769 AARS1; alanine--tRNA ligase, cytoplasmic K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 104691697 MARS2; methionine--tRNA ligase, mitochondrial K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 104692475 SARS1; serine--tRNA ligase, cytoplasmic isoform X1 K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 104695616 DARS2; aspartate--tRNA ligase, mitochondrial isoform X1 K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 104686323 CARS2; probable cysteine--tRNA ligase, mitochondrial isoform X2 K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 104687953 CARS1; cysteine--tRNA ligase, cytoplasmic isoform X1 K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 104684983 EARS2; probable glutamate--tRNA ligase, mitochondrial isoform X1 K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D 104683491 QARS1; glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D 104692400 RARS2; probable arginine--tRNA ligase, mitochondrial isoform X1 K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 104693564 RARS1; arginine--tRNA ligase, cytoplasmic isoform X1 K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 104696805 FARS2; phenylalanine--tRNA ligase, mitochondrial isoform X1 K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 104693092 FARSB; phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D 104693512 histidine--tRNA ligase, cytoplasmic K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 104693553 histidine--tRNA ligase, cytoplasmic-like isoform X1 K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 104690300 NARS2; probable asparagine--tRNA ligase, mitochondrial isoform X3 K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 104698612 NARS1; asparagine--tRNA ligase, cytoplasmic K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
C Trans-editing factors
D 104685724 DTD1; D-aminoacyl-tRNA deacylase 1 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 104688402 DTD2; D-aminoacyl-tRNA deacylase 2 isoform X1 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 104697825 LOW QUALITY PROTEIN: alanyl-tRNA editing protein Aarsd1-like K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferases
C Methyltransferases
C Psudouridine synthases
D 104688632 PUS1; tRNA pseudouridine synthase A isoform X2 K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D 104695024 TRUB1; probable tRNA pseudouridine synthase 1 isoform X1 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D 104686871 PUS7; pseudouridylate synthase 7 homolog isoform X1 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 104698326 PUS7L; pseudouridylate synthase 7 homolog-like protein isoform X1 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D 104698041 NFS1; cysteine desulfurase, mitochondrial K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
D 104687740 TP53RK; EKC/KEOPS complex subunit TP53RK K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D 104693729 OSGEPL1; probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial isoform X1 K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
C Other tRNA modification factors
D 104692979 MTO1; protein MTO1 homolog, mitochondrial isoform X1 K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D 104692182 PTS; 6-pyruvoyl tetrahydrobiopterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D 104694496 SEPHS1; selenide, water dikinase 1 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 120412226 LOW QUALITY PROTEIN: selenide, water dikinase 2-like K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C 104691500 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024