+D Chaperone KO
#
Chaperones and Folding Catalysts - Dendroctonus ponderosae (mountain pine beetle)
%
!
AHeat shock proteins
B HSP110
C 109535356 heat shock 70 kDa protein 4 isoform X1 K09485 HSP110; heat shock protein 110kDa
C 109533357 hypoxia up-regulated protein 1 K09486 HYOU1; hypoxia up-regulated 1
B HSP100
C 109536650 caseinolytic peptidase B protein homolog isoform X1 K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
C 109546189 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial isoform X1 K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
C 125504102 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial isoform X1 K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
B HSP90
C 109537446 heat shock protein 83 K04079 HSP90A; molecular chaperone HtpG
C 109542079 endoplasmin K09487 HSP90B; heat shock protein 90kDa beta
C 109538160 heat shock protein 75 kDa, mitochondrial K09488 TRAP1; TNF receptor-associated protein 1
B HSP70 / DNAK
C 109546256 heat shock 70 kDa protein cognate 2 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 109534002 heat shock 70 kDa protein II isoform X2 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 109539387 heat shock 70 kDa protein cognate 4 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 109541556 heat shock protein 68 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 109538125 heat shock 70 kDa protein cognate 4 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 109538058 heat shock protein 70 A1 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 109538059 heat shock protein 68 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 109538062 heat shock protein 70 A1 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 109533801 heat shock 70 kDa protein isoform X1 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 109545368 heat shock protein 68 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 109533106 heat shock 70 kDa protein isoform X1 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 109539187 endoplasmic reticulum chaperone BiP K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
C 109543948 heat shock 70 kDa protein cognate 5 K04043 dnaK; molecular chaperone DnaK
B HSP60 / Chaperonin
C 109542882 T-complex protein 1 subunit alpha K09493 CCT1; T-complex protein 1 subunit alpha
C 109538428 T-complex protein 1 subunit beta K09494 CCT2; T-complex protein 1 subunit beta
C 109533951 T-complex protein 1 subunit gamma K09495 CCT3; T-complex protein 1 subunit gamma
C 109535693 T-complex protein 1 subunit delta K09496 CCT4; T-complex protein 1 subunit delta
C 109535035 T-complex protein 1 subunit epsilon K09497 CCT5; T-complex protein 1 subunit epsilon
C 109544000 T-complex protein 1 subunit zeta K09498 CCT6; T-complex protein 1 subunit zeta
C 109535432 T-complex protein 1 subunit eta K09499 CCT7; T-complex protein 1 subunit eta
C 109536587 T-complex protein 1 subunit theta isoform X1 K09500 CCT8; T-complex protein 1 subunit theta
C 125505781 T-complex protein 1 subunit theta-like K09500 CCT8; T-complex protein 1 subunit theta
C 125505783 T-complex protein 1 subunit theta-like K09500 CCT8; T-complex protein 1 subunit theta
C 109535768 heat shock protein 60A K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
B HSP47
B HSP40 / DNAJ
C 109533232 dnaJ homolog subfamily A member 4 K09502 DNAJA1; DnaJ homolog subfamily A member 1
C 109546690 dnaJ homolog subfamily A member 2 K09503 DNAJA2; DnaJ homolog subfamily A member 2
C 109534962 protein tumorous imaginal discs, mitochondrial isoform X2 K09504 DNAJA3; DnaJ homolog subfamily A member 3
C 109542658 dnaJ homolog subfamily C member 21 K09506 DNAJA5; DnaJ homolog subfamily A member 5
C 109544188 dnaJ protein homolog 1 K09507 DNAJB1; DnaJ homolog subfamily B member 1
C 109540964 dnaJ protein homolog 1 K09507 DNAJB1; DnaJ homolog subfamily B member 1
C 109541309 dnaJ homolog subfamily B member 6 isoform X1 K09512 DNAJB6; DnaJ homolog subfamily B member 6
C 109538558 dnaJ homolog shv K09517 DNAJB11; DnaJ homolog subfamily B member 11
C 125505296 dnaJ homolog shv-like K09517 DNAJB11; DnaJ homolog subfamily B member 11
C 109541947 dnaJ homolog subfamily B member 12 K09518 DNAJB12; DnaJ homolog subfamily B member 12
C 109538656 dnaJ homolog subfamily B member 13 K09519 DNAJB13; DnaJ homolog subfamily B member 13
C 109543809 dnaJ homolog subfamily C member 1 isoform X1 K09521 DNAJC1; DnaJ homolog subfamily C member 1
C 109543835 dnaJ homolog subfamily C member 2 K09522 DNAJC2; DnaJ homolog subfamily C member 2
C 109541366 dnaJ homolog subfamily C member 3 K09523 DNAJC3; DnaJ homolog subfamily C member 3
C 109542608 dnaJ homolog subfamily C member 4 isoform X1 K09524 DNAJC4; DnaJ homolog subfamily C member 4
C 109540003 dnaJ homolog subfamily C member 5 homolog isoform X2 K09525 DNAJC5; DnaJ homolog subfamily C member 5
C 109535741 dnaJ homolog subfamily C member 7 K09527 DNAJC7; DnaJ homolog subfamily C member 7
C 109537743 dnaJ homolog subfamily C member 8 K09528 DNAJC8; DnaJ homolog subfamily C member 8
C 109534213 J domain-containing protein CG6693 K09529 DNAJC9; DnaJ homolog subfamily C member 9
C 109539545 dnaJ homolog subfamily C member 10 isoform X2 K09530 DNAJC10; DnaJ homolog subfamily C member 10 [EC:1.8.4.-]
C 109542546 dnaJ homolog subfamily C member 11 K09531 DNAJC11; DnaJ homolog subfamily C member 11
C 109536542 J domain-containing protein K09532 DNAJC12; DnaJ homolog subfamily C member 12
C 109533717 dnaJ homolog subfamily C member 13 isoform X1 K09533 DNAJC13; DnaJ homolog subfamily C member 13
C 109539602 dnaJ homolog dnj-5 K09534 DNAJC14; DnaJ homolog subfamily C member 14
C 109545436 dnaJ homolog subfamily C member 16 K09536 DNAJC16; DnaJ homolog subfamily C member 16
C 109536423 dnaJ homolog subfamily C member 17 K09537 DNAJC17; DnaJ homolog subfamily C member 17
C 109546706 mitochondrial import inner membrane translocase subunit TIM14 K09539 DNAJC19; DnaJ homolog subfamily C member 19
C 109539336 dnaJ homolog subfamily C member 22 isoform X1 K19370 DNAJC22; DnaJ homolog subfamily C member 22
C 109539854 translocation protein SEC63 homolog K09540 SEC63; translocation protein SEC63
C 109538500 dnaJ homolog subfamily C member 25 homolog K19371 DNAJC25; DnaJ homolog subfamily C member 25
C 109533315 dnaJ homolog subfamily C member 28 K19373 DNAJC28; DnaJ homolog subfamily C member 28
C 109544243 dnaJ homolog subfamily C member 30, mitochondrial isoform X1 K19374 DNAJC30; DnaJ homolog subfamily C member 30
C 109532728 iron-sulfur cluster co-chaperone protein HscB K04082 hscB; molecular chaperone HscB
B HSP33
B HSP24
C 109542425 grpE protein homolog, mitochondrial K03687 GRPE; molecular chaperone GrpE
B HSP20
C 109537124 alpha-crystallin B chain K09542 CRYAB; crystallin, alpha B
C 109545145 protein lethal(2)essential for life isoform X1 K09542 CRYAB; crystallin, alpha B
C 109539393 alpha-crystallin B chain K09542 CRYAB; crystallin, alpha B
C 109537152 protein lethal(2)essential for life K09542 CRYAB; crystallin, alpha B
C 109537156 heat shock protein 27 K09542 CRYAB; crystallin, alpha B
C 109537013 protein lethal(2)essential for life isoform X1 K09542 CRYAB; crystallin, alpha B
C 109537015 protein lethal(2)essential for life K09542 CRYAB; crystallin, alpha B
C 109537016 protein lethal(2)essential for life K09542 CRYAB; crystallin, alpha B
C 109537017 protein lethal(2)essential for life K09542 CRYAB; crystallin, alpha B
C 109541481 heat shock protein 67B3 K09542 CRYAB; crystallin, alpha B
B HSP15
B HSP10
C 109542964 10 kDa heat shock protein, mitochondrial K04078 groES; chaperonin GroES
C 109543654 10 kDa heat shock protein, mitochondrial K04078 groES; chaperonin GroES
C 125503848 10 kDa heat shock protein, mitochondrial-like K04078 groES; chaperonin GroES
C 125503849 10 kDa heat shock protein, mitochondrial-like K04078 groES; chaperonin GroES
C 125503851 10 kDa heat shock protein, mitochondrial-like K04078 groES; chaperonin GroES
B GimC
C 109546470 prefoldin subunit 1 K09548 PFDN1; prefoldin subunit 1
C 109544130 prefoldin subunit 2 K09549 PFDN2; prefoldin subunit 2
C 109544087 probable prefoldin subunit 4 K09550 PFDN4; prefoldin subunit 4
C 109537970 prefoldin subunit 5 K04797 pfdA; prefoldin alpha subunit
C 109541845 prefoldin subunit 6 K04798 pfdB; prefoldin beta subunit
#
AOther chaperones and cochaperones
B Calnexin / calreticulin
C 109540587 calnexin isoform X1 K08054 CANX; calnexin
C 109542081 calreticulin K08057 CALR; calreticulin
B DegP / HtrA
C 109538837 serine protease HTRA2, mitochondrial K08669 HTRA2; HtrA serine peptidase 2 [EC:3.4.21.108]
B AAA proteases
C 109539136 paraplegin K09552 SPG7; spastic paraplegia 7 [EC:3.4.24.-]
C 109534309 AFG3-like protein 2 K08956 AFG3; AFG3 family protein [EC:3.4.24.-]
B PapD
B SecB
B Sti1 / p60
C 109543496 stress-induced-phosphoprotein 1 K09553 STIP1; stress-induced-phosphoprotein 1
B Cdc37 / p50
C 109537358 hsp90 co-chaperone Cdc37 K09554 CDC37; cell division cycle protein 37
B BAG
C 109542679 BAG family molecular chaperone regulator 2 K09556 BAG2; BCL2-associated athanogene 2
C 109546528 BAG domain-containing protein Samui isoform X1 K09557 BAG3; BCL2-associated athanogene 3
B Others
C 109538339 E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 109546833 hsp70-binding protein 1 K09562 HSPBP1; hsp70-interacting protein
C 109544993 HSPB1-associated protein 1 K19375 HSPBAP1; HSPB1-associated protein 1
C 109540695 protein OPI10 homolog K23327 HIKESHI; protein Hikeshi
C 109543343 cysteine and histidine-rich domain-containing protein morgana isoform X1 K16729 CHORDC1; cysteine and histidine-rich domain-containing protein
C 109537037 protein unc-45 homolog B K21991 UNC45; protein unc-45
C 109536731 protein canopy 4 K22816 CNPY3_4; protein canopy 3/4
C 109542817 torsin-1A K22990 TOR1; torsin-1
C 109541417 SPARC K24262 SPARC; secreted protein acidic and rich in cysteine
C 109532858 small glutamine-rich tetratricopeptide repeat-containing protein beta K16365 SGTA; small glutamine-rich tetratricopeptide repeat-containing protein alpha
C 109540212 tetratricopeptide repeat protein 1 K24926 TTC1; tetratricopeptide repeat protein 1
C 109533643 DNA polymerase interacting tetratricopeptide repeat-containing, protein of 47 kDa isoform X2 K24927 TTC4; tetratricopeptide repeat protein 4
C 109538336 PAT complex subunit CCDC47 K24962 CCDC47; PAT complex subunit CCDC47
C 109540166 LDLR chaperone boca K25366 MESD; LRP chaperone MESD
C 109543553 uncharacterized protein LOC109543553 isoform X1 K26164 RIC3; protein RIC-3
C 109543686 activator of 90 kDa heat shock protein ATPase homolog 1 K26216 AHSA1; activator of Hsp90 ATPase protein 1
C 109534599 transmembrane protein 35B isoform X1 K26241 NACHO; novel acetylcholine receptor chaperone
#
AIntramolecular chaperones
B Subtilisin family
C 109542269 membrane-bound transcription factor site-1 protease isoform X1 K08653 MBTPS1; membrane-bound transcription factor site-1 protease [EC:3.4.21.112]
C 109541004 furin-like protease 1 isoform X4 K01349 FURIN; furin [EC:3.4.21.75]
C 109543176 neuroendocrine convertase 1 K01359 PCSK1; proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93]
C 109535104 neuroendocrine convertase 2 K01360 PCSK2; proprotein convertase subtilisin/kexin type 2 [EC:3.4.21.94]
C 109540902 tripeptidyl-peptidase 2 K01280 TPP2; tripeptidyl-peptidase II [EC:3.4.14.10]
B Papain family
C 109534389 cathepsin B K01363 CTSB; cathepsin B [EC:3.4.22.1]
C 109546849 cathepsin B K01363 CTSB; cathepsin B [EC:3.4.22.1]
C 109535944 cathepsin B K01363 CTSB; cathepsin B [EC:3.4.22.1]
C 109534403 cathepsin B isoform X1 K01363 CTSB; cathepsin B [EC:3.4.22.1]
C 109539774 procathepsin L isoform X1 K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 109545986 cathepsin L K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 109533722 procathepsin L K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 109533723 procathepsin L K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 109543382 procathepsin L isoform X1 K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 109543423 procathepsin L K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 109546215 ervatamin-C K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 109540344 digestive cysteine proteinase 1 isoform X1 K01365 CTSL; cathepsin L [EC:3.4.22.15]
B Other peptidases
B Others
C 109534636 chitooligosaccharidolytic beta-N-acetylglucosaminidase K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 109543022 chitooligosaccharidolytic beta-N-acetylglucosaminidase K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 109541060 chitooligosaccharidolytic beta-N-acetylglucosaminidase isoform X1 K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 109542573 beta-hexosaminidase subunit alpha K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 109542577 beta-hexosaminidase subunit alpha K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
#
AProtein folding catalysts
B Peptidyl prolyl isomerase
C Cyclophilin
D 109538572 peptidyl-prolyl cis-trans isomerase 6 K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 109545656 peptidyl-prolyl cis-trans isomerase B K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 109536501 peptidyl-prolyl cis-trans isomerase D isoform X1 K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
D 109543175 peptidyl-prolyl cis-trans isomerase E K09564 PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]
D 109533165 peptidyl-prolyl cis-trans isomerase K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
D 109537762 peptidyl-prolyl cis-trans isomerase G isoform X1 K09566 PPIG; peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8]
D 109544384 peptidyl-prolyl cis-trans isomerase H K09567 PPIH; peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]
D 109541762 peptidyl-prolyl cis-trans isomerase-like 1 K12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]
D 109546581 RING-type E3 ubiquitin-protein ligase PPIL2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
D 109538439 peptidyl-prolyl cis-trans isomerase-like 3 K12734 PPIL3; peptidyl-prolyl cis-trans isomerase-like 3 [EC:5.2.1.8]
D 109544627 peptidyl-prolyl cis-trans isomerase sig-7 K12735 PPIL4; peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8]
D 109544719 probable inactive peptidyl-prolyl cis-trans isomerase-like 6 K12739 PPIL6; peptidyl-prolyl cis-trans isomerase-like 6 [EC:5.2.1.8]
D 109541843 peptidylprolyl isomerase domain and WD repeat-containing protein 1 K12736 PPWD1; peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8]
D 109536380 spliceosome-associated protein CWC27 homolog K12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]
D 109540195 E3 SUMO-protein ligase RanBP2 isoform X1 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C FKBP
D 109540483 peptidyl-prolyl cis-trans isomerase Fkbp12 K09568 FKBP1; FK506-binding protein 1 [EC:5.2.1.8]
D 109544399 FK506-binding protein 59 K09571 FKBP4_5; FK506-binding protein 4/5 [EC:5.2.1.8]
D 109534511 inactive peptidyl-prolyl cis-trans isomerase shutdown K09572 FKBP6; FK506-binding protein 6 [EC:5.2.1.8]
D 109545637 peptidyl-prolyl cis-trans isomerase FKBP8 K09574 FKBP8; FK506-binding protein 8 [EC:5.2.1.8]
D 109546999 FK506-binding protein 2 K09577 FKBP14; FK506-binding protein 14 [EC:5.2.1.8]
D 109534127 tetratricopeptide repeat protein 9C-like K20097 FKBPL; FK506-binding protein-like
C Parvulin
D 109539481 putative peptidyl-prolyl cis-trans isomerase dodo K09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]
D 109536048 peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 K09579 PIN4; peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [EC:5.2.1.8]
B Protein disulfide isomerase
C 109546353 thioredoxin, mitochondrial K03671 TXN; thioredoxin
C 109537143 thioredoxin-2 K03671 TXN; thioredoxin
C 109534302 thioredoxin, mitochondrial K03671 TXN; thioredoxin
C 109545879 thioredoxin, mitochondrial-like K03671 TXN; thioredoxin
C 109544637 glutaredoxin-C4 isoform X2 K03676 grxC; glutaredoxin 3
C 109541434 glutaredoxin domain-containing cysteine-rich protein CG31559 K17479 GRXCR1; glutaredoxin domain-containing cysteine-rich protein 1
C 109539378 protein disulfide-isomerase K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
C 109540875 protein disulfide-isomerase A3 K08056 PDIA3; protein disulfide-isomerase A3 [EC:5.3.4.1]
C 109540170 protein disulfide-isomerase A5 K09583 PDIA5; protein disulfide-isomerase A5 [EC:5.3.4.1]
C 109537958 protein disulfide-isomerase A6 homolog K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C 109543192 thioredoxin domain-containing protein 5 homolog K13984 TXNDC5; thioredoxin domain-containing protein 5 [EC:5.3.4.1]
C 109538763 protein disulfide-isomerase TMX3 K09585 TMX3; protein disulfide-isomerase [EC:5.3.4.1]
C 109537194 cysteine-rich with EGF-like domain protein 2 isoform X1 K24335 CRELD; protein disulfide-isomerase [EC:5.3.4.1]
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: January 25, 2024