+F Repair protein KO
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DNA Repair and Recombination Proteins - Gordonia sp. KTR9
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D KTR9_2679 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D KTR9_3441 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D KTR9_1179 Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E KTR9_3243 Uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E KTR9_1212 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E KTR9_0861 A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E KTR9_0417 putative EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E KTR9_1104 DNA or RNA helicases of superfamily II K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D KTR9_4251 NTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D KTR9_1253 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D KTR9_2166 dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D KTR9_2679 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D KTR9_3441 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D KTR9_1179 Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D KTR9_4234 putative deoxyribodipyrimidine photolyase K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E KTR9_3243 Uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E KTR9_2659 G:T/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E KTR9_2510 Uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E KTR9_0366 Uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E KTR9_3440 3-methyladenine DNA glycosylase / 8-oxoguanine DNA glycosylase K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E KTR9_1212 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E KTR9_0861 A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E KTR9_4025 3-methyladenine DNA glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E KTR9_1237 Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E KTR9_2002 Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E KTR9_1730 Formamidopyrimidine-DNA glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E KTR9_1972 Formamidopyrimidine-DNA glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E KTR9_0417 putative EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E KTR9_0281 Exonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E KTR9_0509 Exonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E KTR9_1699 Exonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E KTR9_3761 Exonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E KTR9_4287 Endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E KTR9_4918 Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E KTR9_3287 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E KTR9_2767 DNA polymerase I - 3'-5' exonuclease and polymerase domains K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E KTR9_2728 Excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A
E KTR9_2737 Helicase subunit of the DNA excision repair complex K03702 uvrB; excinuclease ABC subunit B
E KTR9_2278 Nuclease subunit of the excinuclease complex K03703 uvrC; excinuclease ABC subunit C
E KTR9_1245 Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E KTR9_3524 Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E KTR9_3528 Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E KTR9_4897 Superfamily I DNA and RNA helicases K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E KTR9_2767 DNA polymerase I - 3'-5' exonuclease and polymerase domains K02335 polA; DNA polymerase I [EC:2.7.7.7]
E KTR9_3287 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F KTR9_1011 DNA-directed RNA polymerase, beta subunit/140 kD subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F KTR9_1012 DNA-directed RNA polymerase, beta' subunit/160 kD subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F KTR9_3636 DNA-directed RNA polymerase, alpha subunit/40 kD subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F KTR9_2261 DNA-directed RNA polymerase, subunit K/omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F KTR9_1474 Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E KTR9_1637 Exonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E KTR9_1636 Exonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E KTR9_2987 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E KTR9_0003 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E KTR9_3220 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E KTR9_0439 ATPase involved in DNA replication K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E KTR9_3041 Nuclease subunit of the excinuclease complex K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E KTR9_0355 DNA polymerase III, gamma/tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E KTR9_3287 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E KTR9_1245 Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E KTR9_3524 Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E KTR9_3528 Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E KTR9_4897 Superfamily I DNA and RNA helicases K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E KTR9_1947 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E KTR9_4866 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E KTR9_4601 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E KTR9_2454 DNA G:T-mismatch repair endonuclease K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E KTR9_2624 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E KTR9_2625 Exonuclease V gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E KTR9_2623 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E KTR9_2119 RecA/RadA recombinase K03553 recA; recombination protein RecA
E KTR9_2218 Holliday junction resolvasome, DNA-binding subunit K03550 ruvA; holliday junction DNA helicase RuvA
E KTR9_2219 Holliday junction resolvasome, helicase subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E KTR9_2217 Holliday junction resolvasome, endonuclease subunit K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E KTR9_1353 hypothetical protein K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
E KTR9_2264 Primosomal protein N' (replication factor Y) - superfamily II helicase K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E KTR9_1837 ATPase involved in DNA repair K03546 sbcC; DNA repair protein SbcC/Rad50
E KTR9_1836 DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E KTR9_2119 RecA/RadA recombinase K03553 recA; recombination protein RecA
E KTR9_0866 putative ATP-dependent serine protease K04485 radA; DNA repair protein RadA/Sms
E KTR9_0004 Recombinational DNA repair ATPase (RecF pathway) K03629 recF; DNA replication and repair protein RecF
E KTR9_3238 RecG-like helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E KTR9_4918 Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E KTR9_3149 Recombinational DNA repair protein (RecF pathway) K03584 recO; DNA repair protein RecO (recombination protein O)
E KTR9_0363 Recombinational DNA repair protein (RecF pathway) K06187 recR; recombination protein RecR
E KTR9_2702 ATPase involved in DNA repair K03631 recN; DNA repair protein RecN (Recombination protein N)
E KTR9_2218 Holliday junction resolvasome, DNA-binding subunit K03550 ruvA; holliday junction DNA helicase RuvA
E KTR9_2219 Holliday junction resolvasome, helicase subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E KTR9_2217 Holliday junction resolvasome, endonuclease subunit K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E KTR9_1837 ATPase involved in DNA repair K03546 sbcC; DNA repair protein SbcC/Rad50
E KTR9_1836 DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
E KTR9_1938 putative ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E KTR9_4497 hypothetical protein K10979 ku; DNA end-binding protein Ku
E KTR9_4500 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E KTR9_5426 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F KTR9_0007 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F KTR9_0006 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F KTR9_0437 Topoisomerase IA K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F KTR9_3252 Bacterial nucleoid DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F KTR9_4918 Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F KTR9_3149 Recombinational DNA repair protein (RecF pathway) K03584 recO; DNA repair protein RecO (recombination protein O)
F KTR9_0363 Recombinational DNA repair protein (RecF pathway) K06187 recR; recombination protein RecR
F KTR9_3287 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F KTR9_0743 Superfamily II DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F KTR9_2728 Excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A
F KTR9_2737 Helicase subunit of the DNA excision repair complex K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D KTR9_1030 DNA-directed DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D KTR9_2994 Nucleotidyltransferase/DNA polymerase involved in DNA repair K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D KTR9_4638 DNA-directed DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D KTR9_2119 RecA/RadA recombinase K03553 recA; recombination protein RecA
D KTR9_2137 SOS-response transcriptional repressors (RecA-mediated autopeptidases) K01356 lexA; repressor LexA [EC:3.4.21.88]
D KTR9_2702 ATPase involved in DNA repair K03631 recN; DNA repair protein RecN (Recombination protein N)
D KTR9_1679 hypothetical protein K14161 imuB; protein ImuB
D KTR9_1685 DNA polymerase III, alpha subunit K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D KTR9_1947 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D KTR9_4866 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D KTR9_4601 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D KTR9_1340 hypothetical protein K14623 dinD; DNA-damage-inducible protein D
D KTR9_2120 regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D KTR9_1891 Rad3-related DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D KTR9_1731 Lhr-like helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D KTR9_4251 NTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D KTR9_1253 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D KTR9_3251 Fructose-2,6-bisphosphatase K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
D KTR9_2698 NTP pyrophosphohydrolase including oxidative damage repair enzymes K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D KTR9_2166 dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D KTR9_3329 Ribonucleotide reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D KTR9_3328 Ribonucleotide reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D KTR9_4385 Ribonucleotide reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D KTR9_2079 Exopolyphosphatase-related protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024