+F Repair protein KO
#
DNA Repair and Recombination Proteins - Guillardia theta
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D GUITHDRAFT_70553 hypothetical protein K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D GUITHDRAFT_162898 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E GUITHDRAFT_93006 hypothetical protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E GUITHDRAFT_54498 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E GUITHDRAFT_43372 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E GUITHDRAFT_64084 APEX; apurinic/apyrimidinic endonuclease family member in base excision repair K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F GUITHDRAFT_157206 POLD1; DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F GUITHDRAFT_61015 POLD1; DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F GUITHDRAFT_58952 POLD1; DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F GUITHDRAFT_68747 POLD2; DNA polymerase delta small subunit K02328 POLD2; DNA polymerase delta subunit 2
F GUITHDRAFT_84065 POLD4; DNA polymerase delta subunit 4 K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F GUITHDRAFT_97375 POLE1; DNA polymerase epsilon catalytic subunit K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F GUITHDRAFT_78908 POLE2; DNA polymerase epsilon subunit B K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F GUITHDRAFT_106949 hypothetical protein K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
E GUITHDRAFT_144189 PCNA; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E GUITHDRAFT_115483 FEN1; flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Short Patch-BER factors
E GUITHDRAFT_100252 XRCC1; XRCC1 in base excision repair K10803 XRCC1; DNA-repair protein XRCC1
E GUITHDRAFT_103430 hypothetical protein K10803 XRCC1; DNA-repair protein XRCC1
D Other BER factors
E GUITHDRAFT_142267 hypothetical protein K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E GUITHDRAFT_134117 hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E GUITHDRAFT_139612 hypothetical protein K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E GUITHDRAFT_52423 hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E GUITHDRAFT_73506 PARP1; PARP1 poly polymerase K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E GUITHDRAFT_137559 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E GUITHDRAFT_111089 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F GUITHDRAFT_137564 XPC; Rad4,mus101,TopBP1 nucleotide excision repair K10838 XPC; xeroderma pigmentosum group C-complementing protein
F GUITHDRAFT_103487 hypothetical protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F GUITHDRAFT_166946 Rad23; Rad23 nucleotide excision repair protein binds to XPC K10839 RAD23; UV excision repair protein RAD23
F GUITHDRAFT_64501 hypothetical protein K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F GUITHDRAFT_86348 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F GUITHDRAFT_160035 hypothetical protein K10609 CUL4; cullin 4
F GUITHDRAFT_158867 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
F GUITHDRAFT_143370 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
F GUITHDRAFT_133804 hypothetical protein K15082 RAD7; DNA repair protein RAD7
F GUITHDRAFT_159018 hypothetical protein K15083 RAD16; DNA repair protein RAD16
F GUITHDRAFT_77334 hypothetical protein K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F GUITHDRAFT_104636 Rpb1; Rpb1, RNA polymerase II largest subunit K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F GUITHDRAFT_159421 hypothetical protein K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F GUITHDRAFT_100722 hypothetical protein K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F GUITHDRAFT_161305 DNA-directed RNA polymerase II subunit, RPB4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F GUITHDRAFT_163048 hypothetical protein K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F GUITHDRAFT_73062 hypothetical protein K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F GUITHDRAFT_71663 hypothetical protein K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F GUITHDRAFT_106397 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F GUITHDRAFT_62660 DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F GUITHDRAFT_175430 RNA polymerase II subunit 9, RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F GUITHDRAFT_88655 hypothetical protein K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F GUITHDRAFT_75411 hypothetical protein K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
E Cul4-CSA complex
F GUITHDRAFT_86348 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F GUITHDRAFT_160035 hypothetical protein K10609 CUL4; cullin 4
F GUITHDRAFT_158867 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
F GUITHDRAFT_143370 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
F GUITHDRAFT_106281 hypothetical protein K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F GUITHDRAFT_151502 hypothetical protein K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E GUITHDRAFT_110061 ERCC3; ERCC3/XPB/SSL2/Rad25 nucleotide excision repair K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E GUITHDRAFT_160030 ERCC2; ERCC2/XPD/Rad3 nucleotide excision repair K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E GUITHDRAFT_139251 TFIIH; SSL1 transcription factor & nucleotide excision repair K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E GUITHDRAFT_87651 hypothetical protein K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E GUITHDRAFT_104031 TFB2; TFB2 transcription factor B2 nucleotide excision repair K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E GUITHDRAFT_151762 hypothetical protein K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E GUITHDRAFT_68598 hypothetical protein K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E GUITHDRAFT_83848 hypothetical protein K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E GUITHDRAFT_162398 hypothetical protein K06634 CCNH; cyclin H
D RPA (replication factor A)
E GUITHDRAFT_166372 RPA1; replication protein A1, 70kDa K07466 RFA1; replication factor A1
E GUITHDRAFT_88915 RPA2; replication protein A2, 32kDa K10739 RFA2; replication factor A2
E GUITHDRAFT_161471 RPA3; replication protein A3, 14kDa K10740 RPA3; replication factor A3
D Other NER factors
E GUITHDRAFT_69282 ERCC1; ERCC1/Rad10 nucleotide excision repair K10849 ERCC1; DNA excision repair protein ERCC-1
E GUITHDRAFT_143405 hypothetical protein K15075 MET18; DNA repair/transcription protein MET18/MMS19
E GUITHDRAFT_152166 hypothetical protein K03869 CUL3; cullin 3
E GUITHDRAFT_81023 hypothetical protein K03872 ELOC; elongin-C
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E GUITHDRAFT_116240 Msh2; Msh2 mismatch repair muts-like protein, meiosis and mitosis K08735 MSH2; DNA mismatch repair protein MSH2
E GUITHDRAFT_99074 hypothetical protein K08737 MSH6; DNA mismatch repair protein MSH6
E GUITHDRAFT_99983 Msh6; Msh6 mismatch repair muts-like protein, meiosis and mitosis K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E GUITHDRAFT_64720 Mlh1; Mlh1 mismatch repair mutL K08734 MLH1; DNA mismatch repair protein MLH1
E GUITHDRAFT_157194 Pms1; Pms1 mismatch repair mutL K10858 PMS2; DNA mismatch repair protein PMS2
D DNA polymerase delta complex
E GUITHDRAFT_157206 POLD1; DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E GUITHDRAFT_61015 POLD1; DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E GUITHDRAFT_58952 POLD1; DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E GUITHDRAFT_68747 POLD2; DNA polymerase delta small subunit K02328 POLD2; DNA polymerase delta subunit 2
E GUITHDRAFT_84065 POLD4; DNA polymerase delta subunit 4 K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E GUITHDRAFT_166372 RPA1; replication protein A1, 70kDa K07466 RFA1; replication factor A1
E GUITHDRAFT_88915 RPA2; replication protein A2, 32kDa K10739 RFA2; replication factor A2
E GUITHDRAFT_161471 RPA3; replication protein A3, 14kDa K10740 RPA3; replication factor A3
D RFC (replication factor C)
E GUITHDRAFT_100231 RFC1; replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
E GUITHDRAFT_160531 RFC1; replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
E GUITHDRAFT_140204 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
E GUITHDRAFT_76379 replication factor C, subunit RFC4 K10755 RFC2_4; replication factor C subunit 2/4
E GUITHDRAFT_101293 RFC3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
E GUITHDRAFT_78796 RFC5; replication factor C subunit 4 K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E GUITHDRAFT_144189 PCNA; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E GUITHDRAFT_157037 EXO1; EXO1 exonuclease 1 DNA repair K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E GUITHDRAFT_40221 hypothetical protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E GUITHDRAFT_133165 hypothetical protein K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
E GUITHDRAFT_131960 hypothetical protein K20776 BABAM; BRISC and BRCA1-A complex member 1
E GUITHDRAFT_100349 hypothetical protein K12173 BRE; BRCA1-A complex subunit BRE
D BRCA1-B complex
E GUITHDRAFT_111516 hypothetical protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E GUITHDRAFT_99144 hypothetical protein K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
E GUITHDRAFT_132908 hypothetical protein K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D BRCA1-C complex
D BRCA complex
E GUITHDRAFT_73670 Rad51; Rad51 recombinase recA K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E GUITHDRAFT_73670 Rad51; Rad51 recombinase recA K04482 RAD51; DNA repair protein RAD51
E GUITHDRAFT_116717 hypothetical protein K10871 RAD51L3; RAD51-like protein 3
E GUITHDRAFT_105379 hypothetical protein K10879 XRCC2; DNA-repair protein XRCC2
D Rad52 family proteins
D Rad54 family proteins
E GUITHDRAFT_52900 hypothetical protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E GUITHDRAFT_68686 hypothetical protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
D RecQ family DNA helicases
E GUITHDRAFT_39919 hypothetical protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E GUITHDRAFT_64555 hypothetical protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E GUITHDRAFT_112459 hypothetical protein K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E GUITHDRAFT_50898 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E GUITHDRAFT_156833 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E GUITHDRAFT_69656 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E GUITHDRAFT_109528 hypothetical protein K15365 RMI2; RecQ-mediated genome instability protein 2
D RPA (replication factor A)
E GUITHDRAFT_166372 RPA1; replication protein A1, 70kDa K07466 RFA1; replication factor A1
E GUITHDRAFT_88915 RPA2; replication protein A2, 32kDa K10739 RFA2; replication factor A2
E GUITHDRAFT_161471 RPA3; replication protein A3, 14kDa K10740 RPA3; replication factor A3
D Protein phosphatase 4
E GUITHDRAFT_87878 hypothetical protein K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E GUITHDRAFT_116855 hypothetical protein K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E GUITHDRAFT_141902 hypothetical protein K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E GUITHDRAFT_55103 hypothetical protein K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E GUITHDRAFT_119835 Smc5; DNA repair in mitosis and meiosis, structural maintenance of chromosomes protein 5, SMC5 K22803 SMC5; structural maintenance of chromosomes protein 5
E GUITHDRAFT_46025 SMC6; SMC6 structural maintenance of chromosomes DNA repair protein K22804 SMC6; structural maintenance of chromosomes protein 6
E GUITHDRAFT_45086 Smc6; Smc6/Rad18 DNA repair protein K22804 SMC6; structural maintenance of chromosomes protein 6
E GUITHDRAFT_43353 hypothetical protein K22804 SMC6; structural maintenance of chromosomes protein 6
E GUITHDRAFT_144064 hypothetical protein K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E GUITHDRAFT_102280 hypothetical protein K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E GUITHDRAFT_146260 hypothetical protein K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E GUITHDRAFT_140294 Mus81; Mus81 endonuclease, DNA recombination, crossover formation in meiosis and mitosis K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E GUITHDRAFT_72981 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
E GUITHDRAFT_109439 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
E GUITHDRAFT_117108 hypothetical protein K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E GUITHDRAFT_46796 hypothetical protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E GUITHDRAFT_157879 hypothetical protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E GUITHDRAFT_100916 hypothetical protein K23456 CFAP410; cilla- and flagella-associated protein
E GUITHDRAFT_136461 hypothetical protein K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7
E GUITHDRAFT_105502 hypothetical protein K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E GUITHDRAFT_109142 hypothetical protein K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
D MRX complex
D DNA Ligase 4 complex
E GUITHDRAFT_111041 LigIV; Lig4/DNL4/DNA ligase IV non-homologous end joining DNA repair K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
E GUITHDRAFT_52423 hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E GUITHDRAFT_134117 hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E GUITHDRAFT_103504 hypothetical protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E GUITHDRAFT_162886 hypothetical protein K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
E GUITHDRAFT_121490 hypothetical protein K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
E GUITHDRAFT_141368 hypothetical protein K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
E GUITHDRAFT_114833 hypothetical protein K25792 JMJD8; jumonji domain-containing protein 8
C FA (Fanconi anemia) pathway
D FA core complex
E GUITHDRAFT_106730 hypothetical protein K10892 FANCE; fanconi anemia group E protein
E GUITHDRAFT_143539 hypothetical protein K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D FA core complex binding factors
E GUITHDRAFT_75848 hypothetical protein K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E GUITHDRAFT_50898 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E GUITHDRAFT_156833 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E GUITHDRAFT_69656 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E GUITHDRAFT_109528 hypothetical protein K15365 RMI2; RecQ-mediated genome instability protein 2
D FANCD2-I complex
D Downstream FA components
E GUITHDRAFT_111516 hypothetical protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D Other FA pathway factors
E GUITHDRAFT_102671 hypothetical protein K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E GUITHDRAFT_73670 Rad51; Rad51 recombinase recA K04482 RAD51; DNA repair protein RAD51
E GUITHDRAFT_113416 hypothetical protein K11137 TELO2; telomere length regulation protein
E GUITHDRAFT_73823 hypothetical protein K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E GUITHDRAFT_84927 hypothetical protein K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
D Ubiquitin ligases
D Others
E GUITHDRAFT_134835 hypothetical protein K23314 WRAP53; telomerase Cajal body protein 1
E GUITHDRAFT_166687 hypothetical protein K24752 WDR70; WD repeat-containing protein 70
E GUITHDRAFT_133165 hypothetical protein K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D GUITHDRAFT_39857 hypothetical protein K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
C B-family DNA polymerases
D GUITHDRAFT_66627 Rev3; Rev3 DNA polymerase zeta K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D GUITHDRAFT_61095 hypothetical protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D GUITHDRAFT_154068 ubiquitin-conjugating enzyme E2 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D GUITHDRAFT_154208 hypothetical protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D GUITHDRAFT_162534 hypothetical protein K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D GUITHDRAFT_70888 hypothetical protein K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D GUITHDRAFT_102917 hypothetical protein K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D GUITHDRAFT_93049 hypothetical protein K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D GUITHDRAFT_147269 hypothetical protein K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D GUITHDRAFT_144189 PCNA; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D GUITHDRAFT_74038 hypothetical protein K26957 GCNA; germ cell nuclear acidic protein
D GUITHDRAFT_59509 hypothetical protein K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D GUITHDRAFT_71598 HUS1; DNA damage checkpoint protein HUS1 K10903 HUS1; HUS1 checkpoint protein
D GUITHDRAFT_121828 RAD1; DNA damage checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D GUITHDRAFT_131644 Rad24; Rad24 DNA damage checkpoint protein K06662 HRAD17; cell cycle checkpoint protein
D GUITHDRAFT_140204 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D GUITHDRAFT_76379 replication factor C, subunit RFC4 K10755 RFC2_4; replication factor C subunit 2/4
D GUITHDRAFT_101293 RFC3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D GUITHDRAFT_78796 RFC5; replication factor C subunit 4 K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D GUITHDRAFT_121828 RAD1; DNA damage checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D GUITHDRAFT_149044 timeless K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D GUITHDRAFT_138882 SWI3; timeless-interacting protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
C Triple T complex
D GUITHDRAFT_113416 hypothetical protein K11137 TELO2; telomere length regulation protein
D GUITHDRAFT_136203 hypothetical protein K20403 TTI1; TELO2-interacting protein 1
C BAG6-UBL4A-GET4 complex
D GUITHDRAFT_136161 hypothetical protein K23390 BAG6; large proline-rich protein BAG6
D GUITHDRAFT_99654 hypothetical protein K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D GUITHDRAFT_82439 ATR; Rad3 DNA damage checkpoint K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D GUITHDRAFT_42827 hypothetical protein K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D GUITHDRAFT_133907 hypothetical protein K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D GUITHDRAFT_96401 14-3-3 protein K06630 YWHAE; 14-3-3 protein epsilon
D GUITHDRAFT_153577 hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon
D GUITHDRAFT_151225 hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon
D GUITHDRAFT_105104 hypothetical protein K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D GUITHDRAFT_110177 hypothetical protein K22422 DONSON; protein downstream neighbor of Son
D GUITHDRAFT_44749 hypothetical protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
D GUITHDRAFT_98347 VPS4; vacuolar protein sorting protein 4 K12196 VPS4; vacuolar protein-sorting-associated protein 4
B Other factors with a suspected DNA repair function
C DNA polymerases
D GUITHDRAFT_110769 hypothetical protein K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
D GUITHDRAFT_101365 hypothetical protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
D GUITHDRAFT_138591 hypothetical protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
D GUITHDRAFT_115788 hypothetical protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Nucleases
D GUITHDRAFT_76035 hypothetical protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D GUITHDRAFT_71213 hypothetical protein K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
D GUITHDRAFT_75675 hypothetical protein K17815 EXO5; exonuclease V [EC:3.1.-.-]
D GUITHDRAFT_69936 hypothetical protein K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
C Helicases
C PSO4 complex
D GUITHDRAFT_159783 hypothetical protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D GUITHDRAFT_93577 hypothetical protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D GUITHDRAFT_164718 hypothetical protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D GUITHDRAFT_111379 hypothetical protein K12861 BCAS2; pre-mRNA-splicing factor SPF27
D GUITHDRAFT_69596 hypothetical protein K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D GUITHDRAFT_40471 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GUITHDRAFT_103538 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GUITHDRAFT_82757 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D GUITHDRAFT_96884 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D GUITHDRAFT_100891 hypothetical protein K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D GUITHDRAFT_162898 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E GUITHDRAFT_93006 hypothetical protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E GUITHDRAFT_141036 hypothetical protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E GUITHDRAFT_54498 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E GUITHDRAFT_43372 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
F GUITHDRAFT_52059 hypothetical protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F GUITHDRAFT_146193 hypothetical protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F GUITHDRAFT_69634 cpRecQ; cpRecQ plastid-targeted DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D GUITHDRAFT_40471 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GUITHDRAFT_103538 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GUITHDRAFT_82757 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D GUITHDRAFT_96884 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024