+D GENES KO #

  KEGG Orthology (KO) - Halothiobacillus neapolitanus

% ! A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:hna00010] D Hneap_1241 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Hneap_0995 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Hneap_1858 phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Hneap_1859 Inositol phosphatase/fructose-16-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D Hneap_0405 fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Hneap_1966 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Hneap_0408 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Hneap_0407 Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Hneap_0120 phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Hneap_0970 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Hneap_0664 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Hneap_0406 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Hneap_1363 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Hneap_1552 2-oxo-acid dehydrogenase E1 subunit, homodimeric type K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D Hneap_1553 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Hneap_1554 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hneap_1375 Alcohol dehydrogenase zinc-binding domain protein K12957 ahr; alcohol/geraniol dehydrogenase (NADP+) [EC:1.1.1.2 1.1.1.183] D Hneap_2041 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Hneap_1298 phosphoglucomutase, alpha-D-glucose phosphate-specific K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Hneap_0489 Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Hneap_1856 Aldose 1-epimerase K01792 E5.1.3.15; glucose-6-phosphate 1-epimerase [EC:5.1.3.15] C 00020 Citrate cycle (TCA cycle) [PATH:hna00020] D Hneap_2141 Citrate (Si)-synthase K01647 CS; citrate synthase [EC:2.3.3.1] D Hneap_1064 aconitate hydratase 2 K01682 acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99] D Hneap_0618 isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D Hneap_1554 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hneap_1989 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Hneap_1988 succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Hneap_2362 succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D Hneap_2361 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D Hneap_2364 succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit D Hneap_2363 succinate dehydrogenase, hydrophobic membrane anchor protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit D Hneap_1441 fumarate lyase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D Hneap_1552 2-oxo-acid dehydrogenase E1 subunit, homodimeric type K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D Hneap_1553 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] C 00030 Pentose phosphate pathway [PATH:hna00030] D Hneap_0995 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Hneap_0996 glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D Hneap_1278 6-phosphogluconolactonase K01057 PGLS; 6-phosphogluconolactonase [EC:3.1.1.31] D Hneap_0997 6-phosphogluconate dehydrogenase, decarboxylating K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] D Hneap_2112 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D Hneap_0409 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D Hneap_0170 transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D Hneap_0695 ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D Hneap_1298 phosphoglucomutase, alpha-D-glucose phosphate-specific K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Hneap_0489 Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Hneap_1168 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Hneap_0405 fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Hneap_1859 Inositol phosphatase/fructose-16-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D Hneap_1858 phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] C 00040 Pentose and glucuronate interconversions [PATH:hna00040] D Hneap_1236 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Hneap_0735 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Hneap_2112 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] C 00051 Fructose and mannose metabolism [PATH:hna00051] D Hneap_0426 ROK family protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D Hneap_0488 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D Hneap_0489 Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Hneap_0492 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47] D Hneap_1858 phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Hneap_1859 Inositol phosphatase/fructose-16-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D Hneap_0029 Ketohexokinase K00846 KHK; ketohexokinase [EC:2.7.1.3] D Hneap_0405 fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Hneap_1966 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Hneap_0493 NAD-dependent epimerase/dehydratase K22252 tld; GDP-6-deoxy-D-talose 4-dehydrogenase [EC:1.1.1.135] D Hneap_0745 PTS system fructose subfamily IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] C 00052 Galactose metabolism [PATH:hna00052] D Hneap_1089 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Hneap_0735 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Hneap_1298 phosphoglucomutase, alpha-D-glucose phosphate-specific K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Hneap_0489 Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Hneap_1241 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Hneap_1858 phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] C 00053 Ascorbate and aldarate metabolism [PATH:hna00053] D Hneap_1236 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Hneap_1011 NAD-dependent epimerase/dehydratase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] C 00500 Starch and sucrose metabolism [PATH:hna00500] D Hneap_0227 sucrose-phosphate synthase K00696 E2.4.1.14; sucrose-phosphate synthase [EC:2.4.1.14] D Hneap_0735 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Hneap_0776 glucose-1-phosphate adenylyltransferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] D Hneap_0774 glycogen/starch synthase, ADP-glucose type K00703 glgA; starch synthase [EC:2.4.1.21] D Hneap_0775 1,4-alpha-glucan branching enzyme K00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18] D Hneap_0621 alpha-glucan phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1] D Hneap_0778 4-alpha-glucanotransferase K00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25] D Hneap_1298 phosphoglucomutase, alpha-D-glucose phosphate-specific K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Hneap_0489 Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Hneap_1241 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Hneap_0995 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Hneap_0426 ROK family protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:hna00520] D Hneap_1398 glycoside hydrolase family 3 domain protein K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] D Hneap_0426 ROK family protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D Hneap_1238 glucosamine/fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Hneap_1967 phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10] D Hneap_2323 UDP-N-acetylglucosamine pyrophosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D Hneap_2140 protein of unknown function UPF0075 K09001 anmK; anhydro-N-acetylmuramic acid kinase [EC:2.7.1.170] D Hneap_1348 phosphoglycolate phosphatase K22292 mupP; N-acetyl-D-muramate 6-phosphate phosphatase [EC:3.1.3.105] D Hneap_0296 aminoglycoside phosphotransferase K07102 amgK; N-acetylmuramate 1-kinase [EC:2.7.1.221] D Hneap_0497 Nucleotidyl transferase K00992 murU; N-acetyl-alpha-D-muramate 1-phosphate uridylyltransferase [EC:2.7.7.99] D Hneap_0765 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D Hneap_1055 UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D Hneap_0630 UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D Hneap_0232 nucleotide sugar dehydrogenase K02474 wbpO; UDP-N-acetyl-D-glucosamine/UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.136 1.1.1.-] D Hneap_0634 N-acylneuraminate cytidylyltransferase K18431 legF; CMP-N,N'-diacetyllegionaminic acid synthase [EC:2.7.7.82] D Hneap_1241 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Hneap_1298 phosphoglucomutase, alpha-D-glucose phosphate-specific K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Hneap_0489 Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Hneap_0735 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Hneap_1236 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Hneap_1089 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Hneap_1011 NAD-dependent epimerase/dehydratase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] D Hneap_0745 PTS system fructose subfamily IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D Hneap_0995 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Hneap_0488 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D Hneap_0492 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47] D Hneap_0493 NAD-dependent epimerase/dehydratase K22252 tld; GDP-6-deoxy-D-talose 4-dehydrogenase [EC:1.1.1.135] D Hneap_0629 DegT/DnrJ/EryC1/StrS aminotransferase K13010 per; perosamine synthetase [EC:2.6.1.102] D Hneap_0776 glucose-1-phosphate adenylyltransferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] C 00620 Pyruvate metabolism [PATH:hna00620] D Hneap_2041 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Hneap_1552 2-oxo-acid dehydrogenase E1 subunit, homodimeric type K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D Hneap_1553 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Hneap_1554 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hneap_1375 Alcohol dehydrogenase zinc-binding domain protein K12957 ahr; alcohol/geraniol dehydrogenase (NADP+) [EC:1.1.1.2 1.1.1.183] D Hneap_0406 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Hneap_1135 acetyl-CoA carboxylase, carboxyl transferase, alpha subunit K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D Hneap_1370 acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D Hneap_1371 acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D Hneap_1157 acetyl-CoA carboxylase, carboxyl transferase, beta subunit K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D Hneap_0071 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K03778 ldhA; D-lactate dehydrogenase [EC:1.1.1.28] D Hneap_2252 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K03778 ldhA; D-lactate dehydrogenase [EC:1.1.1.28] D Hneap_1510 lactoylglutathione lyase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5] D Hneap_1572 hydroxyacylglutathione hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D Hneap_2058 Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] D Hneap_1441 fumarate lyase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D Hneap_0998 Phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D Hneap_1363 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Hneap_1576 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:hna00630] D Hneap_2041 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Hneap_2141 Citrate (Si)-synthase K01647 CS; citrate synthase [EC:2.3.3.1] D Hneap_1064 aconitate hydratase 2 K01682 acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99] D Hneap_2045 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 glcF; glycolate dehydrogenase iron-sulfur subunit [EC:1.1.99.14] D Hneap_2110 phosphoglycolate phosphatase K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18] D Hneap_2111 phosphoglycolate phosphatase K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18] D Hneap_1758 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18] D Hneap_1095 Ribulose-bisphosphate carboxylase K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39] D Hneap_0922 Ribulose-bisphosphate carboxylase K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39] D Hneap_0921 Ribulose-bisphosphate carboxylase K01602 rbcS; ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39] D Hneap_0209 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_0794 glutamine synthetase, type III K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_2370 glutamine synthetase, type III K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_2380 Glutamate--putrescine ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_1871 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Hneap_1554 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hneap_1252 glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein D Hneap_2233 glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D Hneap_1590 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase K01455 E3.5.1.49; formamidase [EC:3.5.1.49] D Hneap_1598 Formamidase K01455 E3.5.1.49; formamidase [EC:3.5.1.49] C 00640 Propanoate metabolism [PATH:hna00640] D Hneap_2041 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Hneap_1554 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hneap_1602 quinone oxidoreductase, YhdH/YhfP family K19745 acuI; acrylyl-CoA reductase (NADPH) [EC:1.3.1.-] D Hneap_1135 acetyl-CoA carboxylase, carboxyl transferase, alpha subunit K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D Hneap_1370 acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D Hneap_1371 acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D Hneap_1157 acetyl-CoA carboxylase, carboxyl transferase, beta subunit K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D Hneap_2371 4-aminobutyrate aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D Hneap_2367 aminotransferase class-III K00822 E2.6.1.18; beta-alanine--pyruvate transaminase [EC:2.6.1.18] D Hneap_1988 succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Hneap_1989 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Hneap_2368 methylmalonate-semialdehyde dehydrogenase K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] D Hneap_1064 aconitate hydratase 2 K01682 acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99] C 00650 Butanoate metabolism [PATH:hna00650] D Hneap_2362 succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D Hneap_2361 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D Hneap_2364 succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit D Hneap_2363 succinate dehydrogenase, hydrophobic membrane anchor protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit D Hneap_2371 4-aminobutyrate aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D Hneap_2202 Aldehyde Dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Hneap_2373 succinic semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Hneap_1902 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Hneap_1901 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] C 00660 C5-Branched dibasic acid metabolism [PATH:hna00660] D Hneap_1902 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Hneap_1901 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Hneap_1988 succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Hneap_1989 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Hneap_1719 3-isopropylmalate dehydratase, large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Hneap_1718 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Hneap_1716 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] C 00562 Inositol phosphate metabolism [PATH:hna00562] D Hneap_2186 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Hneap_0197 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Hneap_2368 methylmalonate-semialdehyde dehydrogenase K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] D Hneap_1966 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:hna00190] D Hneap_1964 NADH-ubiquinone/plastoquinone oxidoreductase chain 3 K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2] D Hneap_1963 NADH-quinone oxidoreductase, B subunit K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2] D Hneap_1962 NADH (or F420H2) dehydrogenase, subunit C K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2] D Hneap_1961 NADH dehydrogenase I, D subunit K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2] D Hneap_1960 NADH-quinone oxidoreductase, E subunit K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2] D Hneap_1959 NADH-quinone oxidoreductase, F subunit K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2] D Hneap_1958 NADH-quinone oxidoreductase, chain G K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2] D Hneap_1957 NADH dehydrogenase (quinone) K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2] D Hneap_1956 NADH-quinone oxidoreductase, chain I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2] D Hneap_1955 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2] D Hneap_1954 NADH-ubiquinone oxidoreductase chain 4L K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2] D Hneap_1953 proton-translocating NADH-quinone oxidoreductase, chain L K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2] D Hneap_1952 proton-translocating NADH-quinone oxidoreductase, chain M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2] D Hneap_1951 proton-translocating NADH-quinone oxidoreductase, chain N K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2] D Hneap_2362 succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D Hneap_2361 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D Hneap_2364 succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit D Hneap_2363 succinate dehydrogenase, hydrophobic membrane anchor protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit D Hneap_1138 ubiquinol-cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8] D Hneap_1139 Cytochrome b/b6 domain protein K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit D Hneap_1140 cytochrome c1 K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit D Hneap_2402 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D Hneap_2405 cytochrome c oxidase, subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9] D Hneap_2406 cytochrome c oxidase, subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9] D Hneap_2398 cytochrome oxidase assembly K02259 COX15; heme a synthase [EC:1.17.99.9] D Hneap_1880 cytochrome c oxidase, cbb3-type, subunit I K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9] D Hneap_1119 cytochrome c oxidase, cbb3-type, subunit I K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9] D Hneap_1879 cytochrome c oxidase, cbb3-type, subunit II K00405 ccoO; cytochrome c oxidase cbb3-type subunit II D Hneap_1877 cytochrome c oxidase, cbb3-type, subunit III K00406 ccoP; cytochrome c oxidase cbb3-type subunit III D Hneap_1294 cytochrome bd ubiquinol oxidase subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7] D Hneap_1295 cytochrome d ubiquinol oxidase, subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7] D Hneap_2327 ATP synthase F1, alpha subunit K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D Hneap_2325 ATP synthase F1, beta subunit K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D Hneap_2326 ATP synthase F1, gamma subunit K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D Hneap_2328 ATP synthase F1, delta subunit K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D Hneap_2324 ATP synthase F1, epsilon subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D Hneap_2331 ATP synthase F0, A subunit K02108 ATPF0A; F-type H+-transporting ATPase subunit a D Hneap_2329 ATP synthase F0, B subunit K02109 ATPF0B; F-type H+-transporting ATPase subunit b D Hneap_2330 ATP synthase F0, C subunit K02110 ATPF0C; F-type H+-transporting ATPase subunit c D Hneap_0971 plasma-membrane proton-efflux P-type ATPase K01535 PMA1; H+-transporting ATPase [EC:7.1.2.1] D Hneap_1402 plasma-membrane proton-efflux P-type ATPase K01535 PMA1; H+-transporting ATPase [EC:7.1.2.1] D Hneap_1272 Inorganic diphosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1] D Hneap_0266 Polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] D Hneap_0972 protein of unknown function DUF344 K22468 ppk2; polyphosphate kinase [EC:2.7.4.34] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation in photosynthetic organisms [PATH:hna00710] D Hneap_1095 Ribulose-bisphosphate carboxylase K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39] D Hneap_0922 Ribulose-bisphosphate carboxylase K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39] D Hneap_0921 Ribulose-bisphosphate carboxylase K01602 rbcS; ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39] D Hneap_0407 Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Hneap_0408 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Hneap_0405 fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Hneap_1859 Inositol phosphatase/fructose-16-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D Hneap_0409 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D Hneap_0695 ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D Hneap_0561 Phosphoribulokinase K00855 PRK; phosphoribulokinase [EC:2.7.1.19] D Hneap_1966 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Hneap_2112 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D Hneap_0998 Phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D Hneap_2058 Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] C 00720 Carbon fixation pathways in prokaryotes C 00680 Methane metabolism [PATH:hna00680] D Hneap_1871 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Hneap_0970 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Hneap_0664 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Hneap_0998 Phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D Hneap_0405 fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Hneap_1859 Inositol phosphatase/fructose-16-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D Hneap_1858 phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Hneap_2041 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Hneap_1363 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Hneap_0120 phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Hneap_1337 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Hneap_1946 Phosphoserine transaminase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Hneap_1338 phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] C 00910 Nitrogen metabolism [PATH:hna00910] D Hneap_1590 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase K01455 E3.5.1.49; formamidase [EC:3.5.1.49] D Hneap_1598 Formamidase K01455 E3.5.1.49; formamidase [EC:3.5.1.49] D Hneap_2206 putative nitrate transporter component, NrtA K15576 nrtA; nitrate/nitrite transport system substrate-binding protein D Hneap_1115 putative nitrate transport protein K15576 nrtA; nitrate/nitrite transport system substrate-binding protein D Hneap_1116 binding-protein-dependent transport systems inner membrane component K15577 nrtB; nitrate/nitrite transport system permease protein D Hneap_2205 nitrate ABC transporter, inner membrane subunit K15577 nrtB; nitrate/nitrite transport system permease protein D Hneap_1117 nitrate ABC transporter, ATPase subunits C and D K15578 nrtC; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4] D Hneap_2204 nitrate ABC transporter, ATPase subunits C and D K15578 nrtC; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4] D Hneap_1112 molybdopterin oxidoreductase K00372 nasC; assimilatory nitrate reductase catalytic subunit [EC:1.7.99.-] D Hneap_1114 nitrite reductase (NAD(P)H), large subunit K26139 nasD; nitrite reductase [NAD(P)H] large subunit [EC:1.7.1.4] D Hneap_1113 nitrite reductase (NAD(P)H), small subunit K26138 nasE; nitrite reductase [NAD(P)H] small subunit [EC:1.7.1.4] D Hneap_0209 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_0794 glutamine synthetase, type III K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_2370 glutamine synthetase, type III K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_2380 Glutamate--putrescine ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_2284 Glutamate synthase (ferredoxin) K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D Hneap_1933 glutamate synthase, small subunit K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D Hneap_2215 cyanate lyase K01725 cynS; cyanate lyase [EC:4.2.1.104] C 00920 Sulfur metabolism [PATH:hna00920] D Hneap_1498 sulfate adenylyltransferase, large subunit K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4] D Hneap_1497 sulfate adenylyltransferase, small subunit K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4] D Hneap_1500 adenylylsulfate kinase K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25] D Hneap_0525 3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] D Hneap_1501 3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] D Hneap_1908 diheme cytochrome SoxA (sulfur oxidation) K17222 soxA; L-cysteine S-thiosulfotransferase [EC:2.8.5.2] D Hneap_1907 cytochrome c, class I K17223 soxX; L-cysteine S-thiosulfotransferase [EC:2.8.5.2] D Hneap_2072 sulfur oxidation protein SoxY-like protein K17226 soxY; sulfur-oxidizing protein SoxY D Hneap_2073 Sulphur oxidation protein SoxZ K17227 soxZ; sulfur-oxidizing protein SoxZ D Hneap_1916 5'-Nucleotidase domain protein K17224 soxB; S-sulfosulfanyl-L-cysteine sulfohydrolase [EC:3.1.6.20] D Hneap_0587 oxidoreductase molybdopterin binding protein K17225 soxC; sulfane dehydrogenase subunit SoxC D Hneap_0586 hypothetical protein K22622 soxD; S-disulfanyl-L-cysteine oxidoreductase SoxD [EC:1.8.2.6] D Hneap_0578 flavodoxin/nitric oxide synthase K00380 cysJ; sulfite reductase (NADPH) flavoprotein alpha-component [EC:1.8.1.2] D Hneap_0596 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4] D Hneap_1221 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4] D Hneap_0298 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4] D Hneap_1845 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17229 fccB; sulfide dehydrogenase [flavocytochrome c] flavoprotein chain [EC:1.8.2.3] D Hneap_1844 cytochrome c class I K17230 fccA; cytochrome subunit of sulfide dehydrogenase D Hneap_1222 Sulfur oxygenase/reductase K16952 sor; sulfur oxygenase/reductase [EC:1.13.11.55] D Hneap_0560 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Hneap_1565 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Hneap_2209 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Hneap_0198 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Hneap_2188 serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Hneap_1837 homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] D Hneap_1589 alpha/beta hydrolase fold protein K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] D Hneap_1511 O-succinylhomoserine sulfhydrylase K10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:hna00061] D Hneap_1135 acetyl-CoA carboxylase, carboxyl transferase, alpha subunit K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D Hneap_1370 acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D Hneap_1371 acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D Hneap_1157 acetyl-CoA carboxylase, carboxyl transferase, beta subunit K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D Hneap_0061 phosphopantetheine-binding protein K02078 acpP; acyl carrier protein D Hneap_0063 acyl carrier protein K02078 acpP; acyl carrier protein D Hneap_1923 acyl carrier protein K02078 acpP; acyl carrier protein D Hneap_1559 conserved hypothetical protein K02078 acpP; acyl carrier protein D Hneap_1925 malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D Hneap_1806 3-oxoacyl-(acyl-carrier-protein) synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D Hneap_0952 Beta-ketoacyl synthase K18473 fabY; acetoacetyl-[acyl-carrier protein] synthase [EC:2.3.1.180] D Hneap_0983 Beta-ketoacyl synthase K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D Hneap_2239 Beta-ketoacyl synthase K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D Hneap_0062 Beta-ketoacyl synthase K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D Hneap_1922 3-oxoacyl-(acyl-carrier-protein) synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D Hneap_2241 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hneap_1924 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hneap_0984 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA K01716 fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14] D Hneap_1443 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D Hneap_0392 short-chain dehydrogenase/reductase SDR K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] C 00062 Fatty acid elongation C 00071 Fatty acid degradation D Hneap_2210 Rubredoxin-type Fe(Cys)4 protein K05297 rubB; rubredoxin---NAD+ reductase [EC:1.18.1.1] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism [PATH:hna00561] D Hneap_2233 glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D Hneap_1000 glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D Hneap_1807 fatty acid/phospholipid synthesis protein PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D Hneap_1883 protein of unknown function DUF205 K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D Hneap_2052 phospholipid/glycerol acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D Hneap_1251 diacylglycerol kinase K00901 dgkA; diacylglycerol kinase (ATP) [EC:2.7.1.107] D Hneap_1926 glycosyl transferase group 1 K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] C 00564 Glycerophospholipid metabolism [PATH:hna00564] D Hneap_2345 Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] D Hneap_1883 protein of unknown function DUF205 K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D Hneap_2052 phospholipid/glycerol acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D Hneap_1251 diacylglycerol kinase K00901 dgkA; diacylglycerol kinase (ATP) [EC:2.7.1.107] D Hneap_2217 SNARE associated Golgi protein-related protein K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4] D Hneap_1437 Phospholipase A(2) K01058 pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4] D Hneap_0572 phosphatidylethanolamine N-methyltransferase, putative K00570 pmtA; phosphatidylethanolamine/phosphatidyl-N-methylethanolamine N-methyltransferase [EC:2.1.1.17 2.1.1.71] D Hneap_1449 phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41] D Hneap_1899 CDP-diacylglycerol/serine O-phosphatidyltransferase K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8] D Hneap_0598 phosphatidylserine decarboxylase K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65] D Hneap_1081 CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] D Hneap_0606 phosphatidylglycerophosphatase A K01095 pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27] D Hneap_0464 phospholipase D/Transphosphatidylase K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-] C 00565 Ether lipid metabolism [PATH:hna00565] D Hneap_1437 Phospholipase A(2) K01058 pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4] D Hneap_2217 SNARE associated Golgi protein-related protein K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4] C 00600 Sphingolipid metabolism C 00590 Arachidonic acid metabolism D Hneap_1437 Phospholipase A(2) K01058 pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4] C 00591 Linoleic acid metabolism D Hneap_1437 Phospholipase A(2) K01058 pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4] C 00592 alpha-Linolenic acid metabolism [PATH:hna00592] D Hneap_1437 Phospholipase A(2) K01058 pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4] C 01040 Biosynthesis of unsaturated fatty acids D Hneap_0010 Arylesterase K10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5] B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:hna00230] D Hneap_1063 ADP-ribose diphosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D Hneap_0524 NUDIX hydrolase K08312 nudE; ADP compounds hydrolase [EC:3.6.1.-] D Hneap_1298 phosphoglucomutase, alpha-D-glucose phosphate-specific K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Hneap_0489 Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Hneap_1168 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Hneap_1153 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D Hneap_2342 phosphoribosylamine/glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D Hneap_1284 phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D Hneap_1929 phosphoribosylglycinamide formyltransferase 2 K08289 purT; phosphoribosylglycinamide formyltransferase 2 [EC:6.3.1.21] D Hneap_1539 phosphoribosylformylglycinamidine synthase K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] D Hneap_1283 phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D Hneap_0259 phosphoribosylaminoimidazole carboxylase, ATPase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] D Hneap_0260 phosphoribosylaminoimidazole carboxylase, catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D Hneap_1886 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D Hneap_1032 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D Hneap_0052 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D Hneap_0544 Adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Hneap_0546 stationary-phase survival protein SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Hneap_0400 conserved hypothetical protein K09913 ppnP; purine/pyrimidine-nucleoside phosphorylase [EC:2.4.2.1 2.4.2.2] D Hneap_2033 protein of unknown function DUF152 K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] D Hneap_1397 phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] D Hneap_0609 inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D Hneap_2190 Nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Hneap_2321 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D Hneap_0860 xanthine dehydrogenase, small subunit K13481 xdhA; xanthine dehydrogenase small subunit [EC:1.17.1.4] D Hneap_0859 xanthine dehydrogenase, molybdopterin binding subunit K13482 xdhB; xanthine dehydrogenase large subunit [EC:1.17.1.4] D Hneap_0610 GMP synthase, large subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Hneap_0857 Guanine deaminase K01487 guaD; guanine deaminase [EC:3.5.4.3] D Hneap_0035 guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8] D Hneap_1010 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Hneap_1009 Ribonucleoside-diphosphate reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D Hneap_0050 deoxyguanosinetriphosphate triphosphohydrolase K01129 dgt; dGTPase [EC:3.1.5.1] D Hneap_0049 metal dependent phosphohydrolase K08722 yfbR; 5'-deoxynucleotidase [EC:3.1.3.89] D Hneap_0033 (p)ppGpp synthetase I, SpoT/RelA K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D Hneap_0404 Ppx/GppA phosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] D Hneap_0804 RelA/SpoT family protein K00951 relA; GTP pyrophosphokinase [EC:2.7.6.5] D Hneap_1805 adenylate cyclase K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Hneap_2007 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D Hneap_0868 adenosine deaminase K21053 ade; adenine deaminase [EC:3.5.4.2] D Hneap_1273 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Hneap_1281 bis(5'nucleosyl)-tetraphosphatase, ApaH K01525 apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [EC:3.6.1.41] D Hneap_1500 adenylylsulfate kinase K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25] D Hneap_1498 sulfate adenylyltransferase, large subunit K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4] D Hneap_1497 sulfate adenylyltransferase, small subunit K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4] D Hneap_0861 hydroxyisourate hydrolase K07127 uraH; 5-hydroxyisourate hydrolase [EC:3.5.2.17] D Hneap_0837 OHCU decarboxylase K13485 PRHOXNB; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.97] D Hneap_0836 urate catabolism protein K16842 hpxB; allantoinase [EC:3.5.2.5] D Hneap_0866 amidase, hydantoinase/carbamoylase family K02083 allC; allantoate deiminase [EC:3.5.3.9] D Hneap_0865 aminotransferase class V K00839 pucG; (S)-ureidoglycine---glyoxylate transaminase [EC:2.6.1.112] D Hneap_0829 Gamma-glutamyltransferase K22602 hpxW; oxamate amidohydrolase [EC:3.5.1.126] C 00240 Pyrimidine metabolism [PATH:hna00240] D Hneap_1562 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Hneap_1563 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D Hneap_1353 aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D Hneap_1147 dihydroorotase, homodimeric type K01465 URA4; dihydroorotase [EC:3.5.2.3] D Hneap_1352 dihydroorotase, multifunctional complex type K01465 URA4; dihydroorotase [EC:3.5.2.3] D Hneap_1048 dihydroorotate dehydrogenase K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2] D Hneap_2026 orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D Hneap_1328 orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D Hneap_1452 uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D Hneap_2190 Nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Hneap_1737 maf protein K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-] D Hneap_0662 CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2] D Hneap_1332 cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D Hneap_0546 stationary-phase survival protein SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Hneap_0400 conserved hypothetical protein K09913 ppnP; purine/pyrimidine-nucleoside phosphorylase [EC:2.4.2.1 2.4.2.2] D Hneap_0843 uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9] D Hneap_1354 Uracil phosphoribosyltransferase K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] D Hneap_0844 Amidohydrolase 3 K01485 codA; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21] D Hneap_0990 deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13] D Hneap_1010 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Hneap_1009 Ribonucleoside-diphosphate reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D Hneap_0049 metal dependent phosphohydrolase K08722 yfbR; 5'-deoxynucleotidase [EC:3.1.3.89] D Hneap_1918 thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D Hneap_0178 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D Hneap_0901 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:hna00250] D Hneap_0353 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hneap_0700 L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16] D Hneap_1915 putative asparaginase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D Hneap_0742 asparagine synthase family amidotransferase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D Hneap_0680 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Hneap_2151 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Hneap_2007 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D Hneap_1032 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D Hneap_1353 aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D Hneap_2371 4-aminobutyrate aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D Hneap_2202 Aldehyde Dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Hneap_2373 succinic semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Hneap_2284 Glutamate synthase (ferredoxin) K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D Hneap_1933 glutamate synthase, small subunit K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D Hneap_0209 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_0794 glutamine synthetase, type III K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_2370 glutamine synthetase, type III K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_2380 Glutamate--putrescine ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_1562 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Hneap_1563 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D Hneap_1238 glucosamine/fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Hneap_1153 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:hna00260] D Hneap_0358 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Hneap_1715 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Hneap_1393 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Hneap_1690 homoserine kinase K02204 thrB2; homoserine kinase type II [EC:2.7.1.39] D Hneap_1395 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D Hneap_1871 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Hneap_2233 glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D Hneap_0120 phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Hneap_1337 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Hneap_1946 Phosphoserine transaminase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Hneap_1338 phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Hneap_1554 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hneap_1252 glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein D Hneap_1899 CDP-diacylglycerol/serine O-phosphatidyltransferase K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8] D Hneap_0696 threonine dehydratase, biosynthetic K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D Hneap_1158 tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D Hneap_1159 tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D Hneap_2200 2,4-diaminobutyrate 4-transaminase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76] D Hneap_0195 diaminobutyrate/2-oxoglutarate aminotransferase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76] D Hneap_0194 L-2,4-diaminobutyric acid acetyltransferase K06718 ectA; L-2,4-diaminobutyric acid acetyltransferase [EC:2.3.1.178] D Hneap_0196 Ectoine synthase K06720 ectC; L-ectoine synthase [EC:4.2.1.108] C 00270 Cysteine and methionine metabolism [PATH:hna00270] D Hneap_2188 serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Hneap_1077 aminotransferase class I and II K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D Hneap_0657 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Hneap_0642 5-methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D Hneap_0413 S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D Hneap_0502 hypothetical protein K00797 speE; spermidine synthase [EC:2.5.1.16] D Hneap_0965 Acyl-homoserine-lactone synthase K13061 rhlI; acyl homoserine lactone synthase [EC:2.3.1.184] D Hneap_0543 purine or other phosphorylase family 1 K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9] D Hneap_2033 protein of unknown function DUF152 K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] D Hneap_1396 methylthioadenosine phosphorylase K19696 mtiP; 5'-methylthioinosine phosphorylase [EC:2.4.2.44] D Hneap_0414 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D Hneap_0358 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Hneap_1715 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Hneap_1393 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Hneap_1837 homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] D Hneap_1589 alpha/beta hydrolase fold protein K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] D Hneap_1511 O-succinylhomoserine sulfhydrylase K10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-] D Hneap_2135 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Hneap_0513 glutamate/cysteine ligase K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2] D Hneap_0512 glutathione synthetase K01920 gshB; glutathione synthase [EC:6.3.2.3] D Hneap_0353 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hneap_0560 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Hneap_1565 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Hneap_2209 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Hneap_0198 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Hneap_1285 cysteine synthase K12339 cysM; S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) [EC:2.5.1.144] D Hneap_1337 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Hneap_1946 Phosphoserine transaminase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Hneap_1338 phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] C 00280 Valine, leucine and isoleucine degradation [PATH:hna00280] D Hneap_2135 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Hneap_1554 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hneap_0051 6-phosphogluconate dehydrogenase NAD-binding protein K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] D Hneap_2368 methylmalonate-semialdehyde dehydrogenase K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] D Hneap_2367 aminotransferase class-III K00822 E2.6.1.18; beta-alanine--pyruvate transaminase [EC:2.6.1.18] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:hna00290] D Hneap_0696 threonine dehydratase, biosynthetic K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D Hneap_1719 3-isopropylmalate dehydratase, large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Hneap_1718 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Hneap_1716 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D Hneap_1902 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Hneap_1901 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Hneap_1900 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D Hneap_1151 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D Hneap_2135 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Hneap_1576 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00300 Lysine biosynthesis [PATH:hna00300] D Hneap_1393 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Hneap_0358 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Hneap_1715 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Hneap_0678 dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D Hneap_1564 dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] D Hneap_0250 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117] D Hneap_1346 acetylornithine and succinylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Hneap_0252 succinyldiaminopimelate transaminase K14267 dapC; N-succinyldiaminopimelate aminotransferase [EC:2.6.1.17] D Hneap_2246 succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D Hneap_0380 diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D Hneap_1835 Orn/DAP/Arg decarboxylase 2 K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D Hneap_2176 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D Hneap_0445 UDP-N-acetylmuramyl-tripeptide synthetase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D Hneap_0446 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] C 00310 Lysine degradation [PATH:hna00310] D Hneap_1554 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hneap_2202 Aldehyde Dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Hneap_2373 succinic semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Hneap_1266 aminotransferase class IV K00824 dat; D-alanine transaminase [EC:2.6.1.21] C 00220 Arginine biosynthesis [PATH:hna00220] D Hneap_1345 ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D Hneap_0680 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Hneap_2151 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Hneap_1105 urea carboxylase K01941 uca; urea carboxylase [EC:6.3.4.6] D Hneap_0798 urea carboxylase K01941 uca; urea carboxylase [EC:6.3.4.6] D Hneap_1106 allophanate hydrolase K01457 atzF; allophanate hydrolase [EC:3.5.1.54] D Hneap_0209 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_0794 glutamine synthetase, type III K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_2370 glutamine synthetase, type III K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_2380 Glutamate--putrescine ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_0353 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hneap_1344 amino-acid N-acetyltransferase K14682 argAB; amino-acid N-acetyltransferase [EC:2.3.1.1] D Hneap_1997 arginine biosynthesis bifunctional protein ArgJ K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1] D Hneap_0179 acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8] D Hneap_2143 N-acetyl-gamma-glutamyl-phosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] D Hneap_1346 acetylornithine and succinylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Hneap_1225 peptidase dimerization domain protein K01438 argE; acetylornithine deacetylase [EC:3.5.1.16] C 00330 Arginine and proline metabolism [PATH:hna00330] D Hneap_0793 Creatininase K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10] D Hneap_0844 Amidohydrolase 3 K01485 codA; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21] D Hneap_1088 Lysine decarboxylase K01584 adiA; arginine decarboxylase [EC:4.1.1.19] D Hneap_2384 agmatinase K01480 speB; agmatinase [EC:3.5.3.11] D Hneap_0502 hypothetical protein K00797 speE; spermidine synthase [EC:2.5.1.16] D Hneap_2379 aminotransferase class-III K12256 spuC; putrescine---pyruvate transaminase [EC:2.6.1.113] D Hneap_2372 Betaine-aldehyde dehydrogenase K12254 kauB; 4-guanidinobutyraldehyde dehydrogenase / NAD-dependent aldehyde dehydrogenase [EC:1.2.1.54 1.2.1.-] D Hneap_1592 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D Hneap_0862 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D Hneap_2383 FAD dependent oxidoreductase K09471 puuB; gamma-glutamylputrescine oxidase [EC:1.4.3.-] D Hneap_1839 pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2] D Hneap_0267 glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D Hneap_1741 gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] D Hneap_2074 proline iminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5] D Hneap_0353 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hneap_1266 aminotransferase class IV K00824 dat; D-alanine transaminase [EC:2.6.1.21] C 00340 Histidine metabolism [PATH:hna00340] D Hneap_0766 ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17] D Hneap_2008 tRNA synthetase class II (G H P and S) K02502 hisZ; ATP phosphoribosyltransferase regulatory subunit D Hneap_0116 phosphoribosyl-ATP diphosphatase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31] D Hneap_0115 Phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19] D Hneap_0113 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D Hneap_0112 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10] D Hneap_0114 imidazoleglycerol phosphate synthase, cyclase subunit K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10] D Hneap_0111 Imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19] D Hneap_0768 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Hneap_1335 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Hneap_1217 inositol monophosphatase K05602 hisN; histidinol-phosphatase [EC:3.1.3.15] D Hneap_0767 histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23] C 00350 Tyrosine metabolism [PATH:hna00350] D Hneap_0353 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hneap_0768 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Hneap_1335 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Hneap_2202 Aldehyde Dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Hneap_2373 succinic semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] C 00360 Phenylalanine metabolism [PATH:hna00360] D Hneap_0353 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hneap_0768 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Hneap_1335 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Hneap_2389 D-amino-acid dehydrogenase K00285 dadA; D-amino-acid dehydrogenase [EC:1.4.5.1] D Hneap_1266 aminotransferase class IV K00824 dat; D-alanine transaminase [EC:2.6.1.21] D Hneap_2177 catalase/peroxidase HPI K03782 katG; catalase-peroxidase [EC:1.11.1.21] D Hneap_1592 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D Hneap_0862 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D Hneap_1197 Rieske (2Fe-2S) iron-sulphur domain protein K05710 hcaC; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin component C 00380 Tryptophan metabolism [PATH:hna00380] D Hneap_1554 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hneap_1592 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D Hneap_0862 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D Hneap_2177 catalase/peroxidase HPI K03782 katG; catalase-peroxidase [EC:1.11.1.21] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:hna00400] D Hneap_1733 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D Hneap_2279 3-dehydroquinate synthase K13829 aroKB; shikimate kinase / 3-dehydroquinate synthase [EC:2.7.1.71 4.2.3.4] D Hneap_1369 3-dehydroquinate dehydratase, type II K03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10] D Hneap_0694 shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] D Hneap_1942 Shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71] D Hneap_1333 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D Hneap_1833 chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D Hneap_2109 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Hneap_0526 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D Hneap_2049 anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18] D Hneap_1160 Phosphoribosylanthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24] D Hneap_2048 Indole-3-glycerol-phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48] D Hneap_1158 tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D Hneap_1159 tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D Hneap_1334 Prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D Hneap_0353 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hneap_0768 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Hneap_1335 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Hneap_2236 endoribonuclease L-PSP K18240 xanB2; chorismate lyase / 3-hydroxybenzoate synthase [EC:4.1.3.40 4.1.3.45] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism [PATH:hna00410] D Hneap_2371 4-aminobutyrate aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D Hneap_1134 pantoate/beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1] D Hneap_2367 aminotransferase class-III K00822 E2.6.1.18; beta-alanine--pyruvate transaminase [EC:2.6.1.18] D Hneap_2368 methylmalonate-semialdehyde dehydrogenase K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] C 00430 Taurine and hypotaurine metabolism D Hneap_0026 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:hna00450] D Hneap_1077 aminotransferase class I and II K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D Hneap_0657 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Hneap_0642 5-methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D Hneap_1195 cysteine desulfurase, SufS subfamily K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D Hneap_0046 thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D Hneap_1498 sulfate adenylyltransferase, large subunit K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4] D Hneap_1497 sulfate adenylyltransferase, small subunit K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4] D Hneap_2397 selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3] D Hneap_1053 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism [PATH:hna00460] D Hneap_0026 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Hneap_1915 putative asparaginase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D Hneap_1871 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Hneap_1590 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase K01455 E3.5.1.49; formamidase [EC:3.5.1.49] D Hneap_1598 Formamidase K01455 E3.5.1.49; formamidase [EC:3.5.1.49] C 00470 D-Amino acid metabolism [PATH:hna00470] D Hneap_1004 alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D Hneap_2388 alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D Hneap_1266 aminotransferase class IV K00824 dat; D-alanine transaminase [EC:2.6.1.21] D Hneap_0452 D-alanine/D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Hneap_0073 glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D Hneap_2265 glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D Hneap_0448 UDP-N-acetylmuramoylalanine/D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D Hneap_0380 diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D Hneap_1835 Orn/DAP/Arg decarboxylase 2 K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D Hneap_2176 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D Hneap_2389 D-amino-acid dehydrogenase K00285 dadA; D-amino-acid dehydrogenase [EC:1.4.5.1] C 00480 Glutathione metabolism [PATH:hna00480] D Hneap_0026 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Hneap_0513 glutamate/cysteine ligase K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2] D Hneap_0512 glutathione synthetase K01920 gshB; glutathione synthase [EC:6.3.2.3] D Hneap_0978 Leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D Hneap_1034 aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] D Hneap_2174 pyridine nucleotide-disulphide oxidoreductase dimerization region K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7] D Hneap_0618 isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D Hneap_0997 6-phosphogluconate dehydrogenase, decarboxylating K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] D Hneap_0996 glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D Hneap_1409 glutathione peroxidase K00432 gpx; glutathione peroxidase [EC:1.11.1.9] D Hneap_2175 Redoxin domain protein K24136 pgdX; glutathione-dependent peroxiredoxin [EC:1.11.1.27] D Hneap_0501 Redoxin domain protein K24138 prx3; glutaredoxin/glutathione-dependent peroxiredoxin [EC:1.11.1.25 1.11.1.27] D Hneap_0502 hypothetical protein K00797 speE; spermidine synthase [EC:2.5.1.16] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation C 00540 Lipopolysaccharide biosynthesis [PATH:hna00540] D Hneap_1442 acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129] D Hneap_2001 UDP-3-0-acyl N-acetylglucosamine deacetylase K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108] D Hneap_1444 UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191] D Hneap_1082 UDP-2,3-diacylglucosamine hydrolase K03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54] D Hneap_1224 lipid-A-disaccharide synthase K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182] D Hneap_1727 tetraacyldisaccharide 4'-kinase K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130] D Hneap_0756 KpsF/GutQ family protein K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13] D Hneap_0663 2-dehydro-3-deoxyphosphooctonate aldolase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55] D Hneap_0755 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45] D Hneap_1725 3-deoxy-D-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38] D Hneap_2122 Three-deoxy-D-manno-octulosonic-acid transferase domain protein K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15] D Hneap_2123 lipid A biosynthesis acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-] D Hneap_2076 lipid A biosynthesis acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-] D Hneap_1481 lipid A biosynthesis acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-] D Hneap_0674 phosphoheptose isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28] D Hneap_1054 hypothetical protein K02841 waaC; lipopolysaccharide heptosyltransferase I [EC:2.4.99.23] C 00542 O-Antigen repeat unit biosynthesis C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:hna00541] D Hneap_0735 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Hneap_1089 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Hneap_1236 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Hneap_1011 NAD-dependent epimerase/dehydratase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] D Hneap_1491 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Hneap_1489 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D Hneap_1487 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D Hneap_1488 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] D Hneap_0488 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D Hneap_0492 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47] D Hneap_0493 NAD-dependent epimerase/dehydratase K22252 tld; GDP-6-deoxy-D-talose 4-dehydrogenase [EC:1.1.1.135] D Hneap_0629 DegT/DnrJ/EryC1/StrS aminotransferase K13010 per; perosamine synthetase [EC:2.6.1.102] D Hneap_2323 UDP-N-acetylglucosamine pyrophosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D Hneap_0630 UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D Hneap_0232 nucleotide sugar dehydrogenase K02474 wbpO; UDP-N-acetyl-D-glucosamine/UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.136 1.1.1.-] C 00550 Peptidoglycan biosynthesis [PATH:hna00550] D Hneap_0765 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D Hneap_1055 UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D Hneap_0451 UDP-N-acetylmuramate/alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D Hneap_0448 UDP-N-acetylmuramoylalanine/D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D Hneap_0445 UDP-N-acetylmuramyl-tripeptide synthetase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D Hneap_0452 D-alanine/D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Hneap_0446 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D Hneap_1450 undecaprenyl diphosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D Hneap_1864 undecaprenol kinase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D Hneap_0139 phosphoesterase PA-phosphatase related protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D Hneap_0447 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D Hneap_0450 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D Hneap_0231 monofunctional biosynthetic peptidoglycan transglycosylase K03814 mtgA; monofunctional glycosyltransferase [EC:2.4.99.28] D Hneap_1936 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Hneap_0650 penicillin-binding protein 1B K05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4] D Hneap_1271 penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D Hneap_0444 Peptidoglycan glycosyltransferase K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D Hneap_1267 Beta-lactamase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D Hneap_0401 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] C 00552 Teichoic acid biosynthesis [PATH:hna00552] D Hneap_1864 undecaprenol kinase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D Hneap_0139 phosphoesterase PA-phosphatase related protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D Hneap_1926 glycosyl transferase group 1 K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis [PATH:hna00543] D Hneap_2188 serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:hna00730] D Hneap_0500 thiamine biosynthesis protein ThiC K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17] D Hneap_1513 Phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7] D Hneap_0801 glycine oxidase ThiO K03153 thiO; glycine oxidase [EC:1.4.3.19] D Hneap_1679 deoxyxylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7] D Hneap_1824 thiazole biosynthesis family protein K03149 thiG; thiazole synthase [EC:2.8.1.10] D Hneap_1240 thiamine-phosphate pyrophosphorylase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3] D Hneap_0605 thiamine-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16] D Hneap_1568 ribosome small subunit-dependent GTPase A K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D Hneap_1273 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism [PATH:hna00740] D Hneap_1867 3,4-dihydroxy-2-butanone 4-phosphate synthase K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D Hneap_1869 riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D Hneap_1866 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D Hneap_1868 riboflavin synthase, alpha subunit K00793 ribE; riboflavin synthase [EC:2.5.1.9] D Hneap_0200 riboflavin biosynthesis protein RibF K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D Hneap_1063 ADP-ribose diphosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D Hneap_1947 NUDIX hydrolase K12152 nudJ; phosphatase NudJ [EC:3.6.1.-] C 00750 Vitamin B6 metabolism [PATH:hna00750] D Hneap_2153 pyridoxamine 5'-phosphate oxidase K00275 pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5] D Hneap_1946 Phosphoserine transaminase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Hneap_1338 phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Hneap_1276 4-hydroxythreonine-4-phosphate dehydrogenase K00097 pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase [EC:1.1.1.262] D Hneap_1385 pyridoxal phosphate biosynthetic protein PdxJ K03474 pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2] D Hneap_1395 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] C 00760 Nicotinate and nicotinamide metabolism [PATH:hna00760] D Hneap_0700 L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16] D Hneap_0476 quinolinate synthetase complex, A subunit K03517 nadA; quinolinate synthase [EC:2.5.1.72] D Hneap_2251 nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D Hneap_0546 stationary-phase survival protein SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Hneap_1740 nicotinate (nicotinamide) nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] D Hneap_1990 NAD+ synthetase K01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1] D Hneap_1704 CinA domain protein K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42] D Hneap_1474 ATP-NAD/AcoX kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] D Hneap_0048 hypothetical protein K00325 pntB; proton-translocating NAD(P)+ transhydrogenase subunit beta [EC:7.1.1.1] D Hneap_2202 Aldehyde Dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Hneap_2373 succinic semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] C 00770 Pantothenate and CoA biosynthesis [PATH:hna00770] D Hneap_1902 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Hneap_1901 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Hneap_1900 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D Hneap_1151 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D Hneap_1133 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11] D Hneap_1134 pantoate/beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1] D Hneap_0308 putative transcriptional acitvator, Baf family K03525 coaX; type III pantothenate kinase [EC:2.7.1.33] D Hneap_0177 phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] D Hneap_1557 pantetheine-phosphate adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D Hneap_1582 dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24] D Hneap_1384 holo-acyl-carrier-protein synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7] D Hneap_2135 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] C 00780 Biotin metabolism [PATH:hna00780] D Hneap_1881 biotin biosynthesis protein BioC K02169 bioC; malonyl-CoA O-methyltransferase [EC:2.1.1.197] D Hneap_0983 Beta-ketoacyl synthase K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D Hneap_2239 Beta-ketoacyl synthase K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D Hneap_0062 Beta-ketoacyl synthase K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D Hneap_1922 3-oxoacyl-(acyl-carrier-protein) synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D Hneap_2241 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hneap_1924 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hneap_1443 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D Hneap_0392 short-chain dehydrogenase/reductase SDR K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D Hneap_1882 hypothetical protein K02170 bioH; pimeloyl-[acyl-carrier protein] methyl ester esterase [EC:3.1.1.85] D Hneap_2068 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D Hneap_1508 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D Hneap_0419 adenosylmethionine-8-amino-7-oxononanoate aminotransferase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62] D Hneap_1887 dethiobiotin synthase K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3] D Hneap_2097 biotin synthase K01012 bioB; biotin synthase [EC:2.8.1.6] D Hneap_0307 biotin/acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism [PATH:hna00785] D Hneap_1264 lipoate-protein ligase B K03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181] D Hneap_1263 lipoic acid synthetase K03644 lipA; lipoyl synthase [EC:2.8.1.8] D Hneap_1554 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hneap_1552 2-oxo-acid dehydrogenase E1 subunit, homodimeric type K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D Hneap_1553 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Hneap_1252 glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein C 00790 Folate biosynthesis [PATH:hna00790] D Hneap_2117 GTP cyclohydrolase I K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16] D Hneap_1681 protein of unknown function DUF198 K09007 folE2; GTP cyclohydrolase IB [EC:3.5.4.16] D Hneap_0042 Alkaline phosphatase K01113 phoD; alkaline phosphatase D [EC:3.1.3.1] D Hneap_0601 dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81] D Hneap_1132 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D Hneap_1969 dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15] D Hneap_0899 Dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D Hneap_1653 Dihydrofolate reductase K18590 dfrA12; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] D Hneap_1156 FolC bifunctional protein K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D Hneap_1867 3,4-dihydroxy-2-butanone 4-phosphate synthase K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D Hneap_1921 Anthranilate synthase K25578 pabB; 4-amino-4-deoxychorismate synthase (2-amino-4-deoxychorismate-forming) component I [EC:2.6.1.123] D Hneap_1920 aminodeoxychorismate lyase K02619 pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38] D Hneap_2118 Dihydrofolate reductase K13938 folM; dihydromonapterin reductase / dihydrofolate reductase [EC:1.5.1.50 1.5.1.3] D Hneap_1680 6-pyruvoyl tetrahydropterin synthase and hypothetical protein K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D Hneap_0913 conserved hypothetical protein K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] D Hneap_0538 Radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D Hneap_0539 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D Hneap_0160 7-cyano-7-deazaguanine reductase K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13] D Hneap_0591 molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D Hneap_0590 molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D Hneap_0588 molybdopterin biosynthesis MoaE protein K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12] D Hneap_1911 molybdenum cofactor biosynthesis protein B K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D Hneap_0589 molybdenum cofactor synthesis domain protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] D Hneap_1107 molybdenum cofactor synthesis domain protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] D Hneap_1108 molybdopterin-guanine dinucleotide biosynthesis protein A K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77] C 00670 One carbon pool by folate [PATH:hna00670] D Hneap_0899 Dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D Hneap_1653 Dihydrofolate reductase K18590 dfrA12; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] D Hneap_2118 Dihydrofolate reductase K13938 folM; dihydromonapterin reductase / dihydrofolate reductase [EC:1.5.1.50 1.5.1.3] D Hneap_0646 Methylenetetrahydrofolate dehydrogenase (NADP(+)) K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D Hneap_1871 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Hneap_1284 phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D Hneap_0052 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D Hneap_2084 methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D Hneap_0657 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Hneap_0901 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] D Hneap_0415 5,10-methylenetetrahydrofolate reductase K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54] D Hneap_0698 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:hna00860] D Hneap_0683 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Hneap_1043 glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70] D Hneap_1239 glutamate-1-semialdehyde-2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D Hneap_2385 aminotransferase class-III K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D Hneap_1172 Porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D Hneap_2161 porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61] D Hneap_1109 Uroporphyrinogen III synthase HEM4 K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] D Hneap_2162 Uroporphyrinogen III synthase HEM4 K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] D Hneap_1934 uroporphyrinogen decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37] D Hneap_2092 Coproporphyrinogen oxidase K00228 CPOX; coproporphyrinogen III oxidase [EC:1.3.3.3] D Hneap_0878 oxygen-independent coproporphyrinogen III oxidase K02495 hemN; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.98.3] D Hneap_0592 protoporphyrinogen oxidase K00231 PPOX; protoporphyrinogen/coproporphyrinogen III oxidase [EC:1.3.3.4 1.3.3.15] D Hneap_0045 ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9] D Hneap_2163 protein of unknown function DUF513 hemX K02496 hemX; uroporphyrin-III C-methyltransferase [EC:2.1.1.107] D Hneap_1111 uroporphyrin-III C-methyltransferase K02302 cysG; uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4] D Hneap_2402 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D Hneap_2398 cytochrome oxidase assembly K02259 COX15; heme a synthase [EC:1.17.99.9] D Hneap_1076 ATP/cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D Hneap_0671 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein K07226 hutZ; heme oxygenase (biliverdin-IX-beta and delta-forming) [EC:1.14.99.58] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:hna00130] D Hneap_2236 endoribonuclease L-PSP K18240 xanB2; chorismate lyase / 3-hydroxybenzoate synthase [EC:4.1.3.40 4.1.3.45] D Hneap_1018 4-hydroxybenzoate polyprenyl transferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] D Hneap_1347 ubiquinone biosynthesis O-methyltransferase K00568 ubiG; 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase [EC:2.1.1.222 2.1.1.64] D Hneap_0893 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family K03185 ubiH; 2-octaprenyl-6-methoxyphenol hydroxylase [EC:1.14.13.-] D Hneap_1326 ubiquinone/menaquinone biosynthesis methyltransferase K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201] D Hneap_0892 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family K03184 ubiF; 3-demethoxyubiquinol 3-hydroxylase [EC:1.14.99.60] D Hneap_0737 flavoprotein WrbA K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:hna00900] D Hneap_1679 deoxyxylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7] D Hneap_1448 1-deoxy-D-xylulose 5-phosphate reductoisomerase K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267] D Hneap_0666 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60] D Hneap_1167 4-diphosphocytidyl-2C-methyl-D-erythritol kinase K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148] D Hneap_0667 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase K01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12] D Hneap_2194 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3] D Hneap_2229 hydroxymethylbutenyl pyrophosphate reductase K03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] D Hneap_1678 Polyprenyl synthetase K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] D Hneap_0164 Trans-hexaprenyltranstransferase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90] D Hneap_1450 undecaprenyl diphosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis [PATH:hna00906] D Hneap_1548 squalene/phytoene synthase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32] C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation [PATH:hna00907] D Hneap_1375 Alcohol dehydrogenase zinc-binding domain protein K12957 ahr; alcohol/geraniol dehydrogenase (NADP+) [EC:1.1.1.2 1.1.1.183] C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D Hneap_0409 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis [PATH:hna00523] D Hneap_1491 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Hneap_1489 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D Hneap_1487 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D Hneap_1488 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides [PATH:hna01053] D Hneap_0962 Phosphopantetheinyl transferase component of siderophore synthetase-like protein K02362 entD; enterobactin synthetase component D [EC:6.3.2.14 2.7.8.-] D Hneap_2059 Chorismate mutase K04782 pchB; isochorismate pyruvate lyase [EC:4.2.99.21] C 01055 Biosynthesis of vancomycin group antibiotics D Hneap_1489 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis C 00332 Carbapenem biosynthesis [PATH:hna00332] D Hneap_0267 glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D Hneap_1741 gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] C 00261 Monobactam biosynthesis [PATH:hna00261] D Hneap_1498 sulfate adenylyltransferase, large subunit K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4] D Hneap_1497 sulfate adenylyltransferase, small subunit K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4] D Hneap_0358 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Hneap_1715 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Hneap_0678 dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D Hneap_1564 dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:hna00521] D Hneap_1241 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Hneap_1298 phosphoglucomutase, alpha-D-glucose phosphate-specific K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Hneap_0489 Phosphomannomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Hneap_2186 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Hneap_0197 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Hneap_1491 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Hneap_1489 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D Hneap_1487 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D Hneap_1488 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 00524 Neomycin, kanamycin and gentamicin biosynthesis D Hneap_1241 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] C 00525 Acarbose and validamycin biosynthesis [PATH:hna00525] D Hneap_1491 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Hneap_1489 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] C 00401 Novobiocin biosynthesis [PATH:hna00401] D Hneap_1334 Prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D Hneap_0353 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hneap_0768 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Hneap_1335 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D Hneap_2109 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Hneap_0526 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis D Hneap_1925 malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D Hneap_2241 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hneap_1924 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hneap_0392 short-chain dehydrogenase/reductase SDR K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics D Hneap_0061 phosphopantetheine-binding protein K02078 acpP; acyl carrier protein D Hneap_0063 acyl carrier protein K02078 acpP; acyl carrier protein D Hneap_1923 acyl carrier protein K02078 acpP; acyl carrier protein D Hneap_1559 conserved hypothetical protein K02078 acpP; acyl carrier protein C 00999 Biosynthesis of various plant secondary metabolites [PATH:hna00999] D Hneap_0413 S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D Hneap_0694 shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation [PATH:hna00362] D Hneap_1991 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D Hneap_1703 Carboxymuconolactone decarboxylase K01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44] C 00627 Aminobenzoate degradation D Hneap_1592 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D Hneap_0862 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation C 00361 Chlorocyclohexane and chlorobenzene degradation C 00623 Toluene degradation C 00622 Xylene degradation D Hneap_1991 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00633 Nitrotoluene degradation [PATH:hna00633] D Hneap_1721 NADH:flavin oxidoreductase/NADH oxidase K10680 nemA; N-ethylmaleimide reductase [EC:1.-.-.-] C 00642 Ethylbenzene degradation C 00643 Styrene degradation [PATH:hna00643] D Hneap_1592 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D Hneap_0862 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] C 00791 Atrazine degradation [PATH:hna00791] D Hneap_0846 amidohydrolase, AtzE family K19837 atzE; 1-carboxybiuret hydrolase [EC:3.5.1.131] D Hneap_1106 allophanate hydrolase K01457 atzF; allophanate hydrolase [EC:3.5.1.54] D Hneap_0850 isochorismatase hydrolase K23359 biuH; biuret amidohydrolase [EC:3.5.1.84] D Hneap_0848 isochorismatase hydrolase K23359 biuH; biuret amidohydrolase [EC:3.5.1.84] D Hneap_1105 urea carboxylase K01941 uca; urea carboxylase [EC:6.3.4.6] D Hneap_0798 urea carboxylase K01941 uca; urea carboxylase [EC:6.3.4.6] C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation D Hneap_1991 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00626 Naphthalene degradation C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:hna03020] D Hneap_0316 DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D Hneap_0317 DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D Hneap_0347 DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D Hneap_0034 DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] C 03022 Basal transcription factors C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:hna03010] D Hneap_1330 ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1 D Hneap_1454 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D Hneap_0329 ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D Hneap_0346 ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D Hneap_0340 ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D Hneap_1383 ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D Hneap_0319 ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D Hneap_0337 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D Hneap_2043 ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D Hneap_0322 ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D Hneap_0345 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D Hneap_0318 ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D Hneap_0344 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D Hneap_0336 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D Hneap_1464 ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D Hneap_2006 ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D Hneap_0332 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D Hneap_1382 ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D Hneap_0327 ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D Hneap_2024 ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D Hneap_1931 ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D Hneap_0313 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D Hneap_0326 ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D Hneap_0323 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D Hneap_0324 ribosomal protein L4/L1e K02926 RP-L4; large subunit ribosomal protein L4 D Hneap_0335 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Hneap_0338 ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D Hneap_0315 ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D Hneap_1381 ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D Hneap_0314 ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D Hneap_0312 ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Hneap_2044 ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D Hneap_0333 ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D Hneap_0342 ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D Hneap_0330 ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D Hneap_0348 ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D Hneap_0339 ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D Hneap_2003 ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D Hneap_1317 ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D Hneap_0270 ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D Hneap_0328 ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D Hneap_0325 Ribosomal protein L25/L23 K02892 RP-L23; large subunit ribosomal protein L23 D Hneap_0334 ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D Hneap_1169 ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 K02897 RP-L25; large subunit ribosomal protein L25 D Hneap_0269 ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D Hneap_2021 ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D Hneap_0331 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Hneap_0341 ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D Hneap_2094 ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D Hneap_1808 ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D Hneap_2022 ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D Hneap_2414 ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D Hneap_1318 ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D Hneap_0110 ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 D Hneap_R0052 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Hneap_R0016 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Hneap_R0019 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Hneap_R0049 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Hneap_R0020 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Hneap_R0048 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:hna00970] D Hneap_R0021 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Hneap_R0018 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Hneap_R0050 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Hneap_R0031 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hneap_R0033 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hneap_R0039 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hneap_R0023 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hneap_R0040 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Hneap_R0014 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Hneap_R0044 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Hneap_R0041 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Hneap_R0037 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Hneap_R0038 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Hneap_R0012 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Hneap_R0043 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Hneap_R0005 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Hneap_R0028 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Hneap_R0034 tRNA-His K14226 tRNA-His; tRNA His D Hneap_R0017 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Hneap_R0051 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Hneap_R0009 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hneap_R0027 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hneap_R0042 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hneap_R0047 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hneap_R0030 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hneap_R0015 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Hneap_R0011 tRNA-Met K14230 tRNA-Met; tRNA Met D Hneap_R0035 tRNA-Met K14230 tRNA-Met; tRNA Met D Hneap_R0036 tRNA-Met K14230 tRNA-Met; tRNA Met D Hneap_R0001 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Hneap_R0029 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Hneap_R0002 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Hneap_R0032 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Hneap_R0022 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Hneap_R0008 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Hneap_R0046 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Hneap_R0006 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Hneap_R0045 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Hneap_R0003 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Hneap_R0007 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Hneap_R0004 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Hneap_R0026 tRNA-Val K14237 tRNA-Val; tRNA Val D Hneap_R0013 tRNA-Val K14237 tRNA-Val; tRNA Val D Hneap_0683 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Hneap_1245 glutamyl-tRNA(Gln) amidotransferase, A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D Hneap_1244 glutamyl-tRNA(Gln) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Hneap_1247 glutamyl-tRNA(Gln) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D Hneap_1220 glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18] D Hneap_0357 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Hneap_0475 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Hneap_2050 glycyl-tRNA synthetase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D Hneap_2051 glycyl-tRNA synthetase, beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D Hneap_1320 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Hneap_1560 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Hneap_1084 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Hneap_1053 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Hneap_2084 methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D Hneap_1377 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Hneap_1744 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Hneap_2232 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Hneap_0422 lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D Hneap_2114 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Hneap_0635 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Hneap_2195 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Hneap_1316 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Hneap_1315 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Hneap_2138 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Hneap_2020 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:hna03060] D Hneap_0343 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Hneap_0310 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Hneap_1965 preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Hneap_2184 protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD D Hneap_2185 protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF D Hneap_2183 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Hneap_2411 membrane protein insertase, YidC/Oxa1 family domain containing K03217 yidC; YidC/Oxa1 family membrane protein insertase D Hneap_1999 preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Hneap_2346 protein-export protein SecB K03071 secB; preprotein translocase subunit SecB D Hneap_0384 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Hneap_R0025 ffs; SRP RNA; RNA component of signal recognition particle K01983 ffs; SRP RNA D Hneap_1544 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Hneap_0117 twin-arginine translocation protein, TatA/E family subunit K03116 tatA; sec-independent protein translocase protein TatA D Hneap_0118 twin-arginine translocation protein, TatB subunit K03117 tatB; sec-independent protein translocase protein TatB D Hneap_0119 Sec-independent protein translocase, TatC subunit K03118 tatC; sec-independent protein translocase protein TatC D Hneap_1390 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D Hneap_2231 lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:hna04122] D Hneap_0560 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Hneap_1565 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Hneap_2209 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Hneap_0198 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Hneap_1905 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D Hneap_1948 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D Hneap_0588 molybdopterin biosynthesis MoaE protein K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12] D Hneap_0591 molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D Hneap_1853 thiamineS protein K03636 moaD; sulfur-carrier protein D Hneap_1047 UBA/THIF-type NAD/FAD binding protein K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80] D Hneap_0590 molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D Hneap_1911 molybdenum cofactor biosynthesis protein B K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D Hneap_2136 thiamine biosynthesis protein ThiS K03154 thiS; sulfur carrier protein C 03050 Proteasome C 03018 RNA degradation [PATH:hna03018] D Hneap_0992 NUDIX hydrolase K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-] D Hneap_1756 ribonuclease, Rne/Rng family K08300 rne; ribonuclease E [EC:3.1.26.12] D Hneap_0970 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Hneap_0664 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Hneap_1463 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D Hneap_1362 DEAD/DEAH box helicase domain protein K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] D Hneap_0351 ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] D Hneap_1927 DEAD/DEAH box helicase domain protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Hneap_0299 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D Hneap_2341 transcription termination factor Rho K03628 rho; transcription termination factor Rho D Hneap_1472 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK D Hneap_0620 chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Hneap_2013 RNA chaperone Hfq K03666 hfq; host factor-I protein D Hneap_0266 Polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] D Hneap_0972 protein of unknown function DUF344 K22468 ppk2; polyphosphate kinase [EC:2.7.4.34] D Hneap_1131 poly(A) polymerase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] B B 09124 Replication and repair C 03030 DNA replication [PATH:hna03030] D Hneap_1410 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Hneap_1827 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Hneap_0583 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Hneap_0769 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Hneap_1917 DNA-directed DNA polymerase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Hneap_1742 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Hneap_1378 DNA polymerase III chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] D Hneap_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Hneap_1003 replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D Hneap_0462 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D Hneap_0025 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Hneap_1650 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Hneap_1829 Ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D Hneap_1223 Ribonuclease H K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Hneap_1688 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Hneap_0163 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03410 Base excision repair [PATH:hna03410] D Hneap_1074 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D Hneap_2154 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D Hneap_1851 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D Hneap_2023 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D Hneap_1417 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D Hneap_0007 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D Hneap_0039 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D Hneap_1688 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Hneap_0403 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Hneap_0163 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03420 Nucleotide excision repair [PATH:hna03420] D Hneap_1978 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D Hneap_0024 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A D Hneap_0350 excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B D Hneap_1803 excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C D Hneap_1120 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Hneap_1688 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Hneap_0163 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03430 Mismatch repair [PATH:hna03430] D Hneap_0653 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS D Hneap_2015 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL D Hneap_1120 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Hneap_1071 Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1] D Hneap_0428 exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D Hneap_1677 exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D Hneap_0403 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Hneap_0025 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Hneap_1650 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Hneap_0583 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Hneap_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Hneap_0769 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Hneap_1742 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Hneap_1917 DNA-directed DNA polymerase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Hneap_1410 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Hneap_1827 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Hneap_1378 DNA polymerase III chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] D Hneap_0163 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Hneap_1631 D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D Hneap_0202 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] C 03440 Homologous recombination [PATH:hna03440] D Hneap_0403 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Hneap_0025 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Hneap_1650 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Hneap_0003 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF D Hneap_1386 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) D Hneap_0771 recombination protein RecR K06187 recR; recombination protein RecR D Hneap_0354 RecA protein K03553 recA; recombination protein RecA D Hneap_1688 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Hneap_0530 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA D Hneap_0531 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D Hneap_0529 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D Hneap_0124 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D Hneap_0615 putative transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D Hneap_1981 exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5] D Hneap_0563 exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5] D Hneap_1980 exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D Hneap_0583 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Hneap_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Hneap_0769 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Hneap_1742 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Hneap_1917 DNA-directed DNA polymerase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Hneap_1410 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Hneap_1827 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Hneap_1378 DNA polymerase III chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] D Hneap_0799 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] C 03450 Non-homologous end-joining C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus and Lyssavirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:hna02010] D Hneap_2206 putative nitrate transporter component, NrtA K15576 nrtA; nitrate/nitrite transport system substrate-binding protein D Hneap_1115 putative nitrate transport protein K15576 nrtA; nitrate/nitrite transport system substrate-binding protein D Hneap_1116 binding-protein-dependent transport systems inner membrane component K15577 nrtB; nitrate/nitrite transport system permease protein D Hneap_2205 nitrate ABC transporter, inner membrane subunit K15577 nrtB; nitrate/nitrite transport system permease protein D Hneap_1117 nitrate ABC transporter, ATPase subunits C and D K15578 nrtC; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4] D Hneap_2204 nitrate ABC transporter, ATPase subunits C and D K15578 nrtC; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4] D Hneap_0809 molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 modA; molybdate transport system substrate-binding protein D Hneap_0808 molybdate ABC transporter, inner membrane subunit K02018 modB; molybdate transport system permease protein D Hneap_0807 molybdate ABC transporter, ATPase subunit K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D Hneap_2377 extracellular solute-binding protein family 1 K11073 potF; putrescine transport system substrate-binding protein D Hneap_2374 binding-protein-dependent transport systems inner membrane component K11074 potI; putrescine transport system permease protein D Hneap_2375 binding-protein-dependent transport systems inner membrane component K11075 potH; putrescine transport system permease protein D Hneap_2376 spermidine/putrescine ABC transporter ATPase subunit K11076 potG; putrescine transport system ATP-binding protein [EC:7.6.2.16] D Hneap_0763 toluene tolerance family protein K07323 mlaC; phospholipid transport system substrate-binding protein D Hneap_0761 Mammalian cell entry related domain protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein D Hneap_1360 Mammalian cell entry related domain protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein D Hneap_0760 protein of unknown function DUF140 K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein D Hneap_1358 protein of unknown function DUF140 K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein D Hneap_0764 anti-sigma-factor antagonist K07122 mlaB; phospholipid transport system transporter-binding protein D Hneap_0759 ABC transporter related protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein D Hneap_1359 ABC transporter related protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein D Hneap_0869 basic membrane lipoprotein K07335 bmpA; basic membrane protein A and related proteins D Hneap_0853 basic membrane lipoprotein K07335 bmpA; basic membrane protein A and related proteins D Hneap_0852 inner-membrane translocator K23535 nupB; general nucleoside transport system permease protein D Hneap_0839 inner-membrane translocator K23535 nupB; general nucleoside transport system permease protein D Hneap_0851 inner-membrane translocator K23536 nupC; general nucleoside transport system permease protein D Hneap_0840 inner-membrane translocator K23536 nupC; general nucleoside transport system permease protein D Hneap_0838 ABC transporter related protein K23537 nupA; general nucleoside transport system ATP-binding protein D Hneap_0849 ABC transporter related protein K23537 nupA; general nucleoside transport system ATP-binding protein D Hneap_1797 phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D Hneap_1796 phosphate ABC transporter, inner membrane subunit PstC K02037 pstC; phosphate transport system permease protein D Hneap_1795 phosphate ABC transporter, inner membrane subunit PstA K02038 pstA; phosphate transport system permease protein D Hneap_1794 phosphate ABC transporter, ATPase subunit K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Hneap_1103 urea ABC transporter, urea binding protein K11959 urtA; urea transport system substrate-binding protein D Hneap_1597 urea ABC transporter, urea binding protein K11959 urtA; urea transport system substrate-binding protein D Hneap_1102 urea ABC transporter, permease protein UrtB K11960 urtB; urea transport system permease protein D Hneap_1596 urea ABC transporter, permease protein UrtB K11960 urtB; urea transport system permease protein D Hneap_1595 urea ABC transporter, permease protein UrtC K11961 urtC; urea transport system permease protein D Hneap_1101 urea ABC transporter, permease protein UrtC K11961 urtC; urea transport system permease protein D Hneap_1100 urea ABC transporter, ATP-binding protein UrtD K11962 urtD; urea transport system ATP-binding protein D Hneap_1594 urea ABC transporter, ATP-binding protein UrtD K11962 urtD; urea transport system ATP-binding protein D Hneap_1099 urea ABC transporter, ATP-binding protein UrtE K11963 urtE; urea transport system ATP-binding protein D Hneap_1593 urea ABC transporter, ATP-binding protein UrtE K11963 urtE; urea transport system ATP-binding protein D Hneap_0393 extracellular solute-binding protein family 5 K13893 yejA; microcin C transport system substrate-binding protein D Hneap_0396 binding-protein-dependent transport systems inner membrane component K13894 yejB; microcin C transport system permease protein D Hneap_0397 binding-protein-dependent transport systems inner membrane component K13895 yejE; microcin C transport system permease protein D Hneap_0982 ABC transporter related protein K13896 yejF; microcin C transport system ATP-binding protein D Hneap_1015 periplasmic solute binding protein K09815 znuA; zinc transport system substrate-binding protein D Hneap_1013 ABC-3 protein K09816 znuB; zinc transport system permease protein D Hneap_1014 ABC transporter related protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D Hneap_1507 lipopolysaccharide biosynthesis protein K10107 kpsE; capsular polysaccharide transport system permease protein D Hneap_1506 ABC-2 type transporter K09688 kpsM; capsular polysaccharide transport system permease protein D Hneap_1505 ABC transporter related protein K09689 kpsT; capsular polysaccharide transport system ATP-binding protein [EC:7.6.2.12] D Hneap_0486 ABC-2 type transporter K09690 wzm; homopolymeric O-antigen transport system permease protein D Hneap_0487 ABC transporter related protein K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14] D Hneap_2120 ABC-2 type transporter, NodJ family K09694 nodJ; lipooligosaccharide transport system permease protein D Hneap_2121 ABC transporter related protein K09695 nodI; lipooligosaccharide transport system ATP-binding protein D Hneap_0224 lipoprotein releasing system, transmembrane protein, LolC/E family K09808 lolC_E; lipoprotein-releasing system permease protein D Hneap_0225 lipoprotein releasing system, ATP-binding protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] D Hneap_1231 permease YjgP/YjgQ family protein K07091 lptF; lipopolysaccharide export system permease protein D Hneap_1230 permease YjgP/YjgQ family protein K11720 lptG; lipopolysaccharide export system permease protein D Hneap_0752 ABC transporter related protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5] D Hneap_1546 protein of unknown function DUF214 K09811 ftsX; cell division transport system permease protein D Hneap_1545 cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein D Hneap_1728 lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6] D Hneap_1001 ABC transporter related protein K24821 atm1; ATP-binding cassette, subfamily B, heavy metal transporter D Hneap_1293 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC K16012 cydC; ATP-binding cassette, subfamily C, bacterial CydC D Hneap_1292 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD K16013 cydD; ATP-binding cassette, subfamily C, bacterial CydD D Hneap_1179 ABC transporter domain protein K02471 bacA; vitamin B12/bleomycin/antimicrobial peptide transport system ATP-binding/permease protein C 02060 Phosphotransferase system (PTS) [PATH:hna02060] D Hneap_0744 Phosphotransferase system, phosphocarrier protein HPr K02784 ptsH; phosphocarrier protein HPr D Hneap_0745 PTS system fructose subfamily IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D Hneap_0993 PTSINtr with GAF domain, PtsP K08484 ptsP; phosphotransferase system, enzyme I, PtsP [EC:2.7.3.9] D Hneap_0748 putative PTS IIA-like nitrogen-regulatory protein PtsN K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-] C 03070 Bacterial secretion system [PATH:hna03070] D Hneap_0498 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein D Hneap_0762 outer membrane efflux protein K12340 tolC; outer membrane protein D Hneap_1021 outer membrane efflux protein K12340 tolC; outer membrane protein D Hneap_0141 general secretion pathway protein D K02453 gspD; general secretion pathway protein D D Hneap_0140 general secretion pathway protein C K02452 gspC; general secretion pathway protein C D Hneap_0143 general secretion pathway protein F K02455 gspF; general secretion pathway protein F D Hneap_0144 general secretion pathway protein G K02456 gspG; general secretion pathway protein G D Hneap_0146 general secretion pathway protein I K02458 gspI; general secretion pathway protein I D Hneap_0147 general secretion pathway protein J K02459 gspJ; general secretion pathway protein J D Hneap_0148 General secretion pathway protein K K02460 gspK; general secretion pathway protein K D Hneap_0149 Type II secretory pathway component PulL-like protein K02461 gspL; general secretion pathway protein L D Hneap_0150 General secretion pathway M protein K02462 gspM; general secretion pathway protein M D Hneap_0142 general secretory pathway protein E K02454 gspE; general secretion pathway protein E [EC:7.4.2.8] D Hneap_2184 protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD D Hneap_2185 protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF D Hneap_0310 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Hneap_1965 preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Hneap_0343 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Hneap_2183 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Hneap_2411 membrane protein insertase, YidC/Oxa1 family domain containing K03217 yidC; YidC/Oxa1 family membrane protein insertase D Hneap_1999 preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Hneap_1544 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Hneap_2346 protein-export protein SecB K03071 secB; preprotein translocase subunit SecB D Hneap_0384 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Hneap_0117 twin-arginine translocation protein, TatA/E family subunit K03116 tatA; sec-independent protein translocase protein TatA D Hneap_0118 twin-arginine translocation protein, TatB subunit K03117 tatB; sec-independent protein translocase protein TatB D Hneap_0119 Sec-independent protein translocase, TatC subunit K03118 tatC; sec-independent protein translocase protein TatC D Hneap_1609 Lytic transglycosylase catalytic K03194 virB1; type IV secretion system protein VirB1 D Hneap_1649 TRAG family protein K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8] B B 09132 Signal transduction C 02020 Two-component system [PATH:hna02020] D Hneap_2267 histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D Hneap_2266 two component transcriptional regulator PhoB, winged helix family K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB D Hneap_0042 Alkaline phosphatase K01113 phoD; alkaline phosphatase D [EC:3.1.3.1] D Hneap_1797 phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D Hneap_0208 integral membrane sensor signal transduction histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3] D Hneap_0207 two component transcriptional regulator, winged helix family K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR D Hneap_0040 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Hneap_1392 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Hneap_1993 integral membrane sensor signal transduction histidine kinase K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3] D Hneap_1992 two component transcriptional regulator, winged helix family K07663 creB; two-component system, OmpR family, catabolic regulation response regulator CreB D Hneap_0277 efflux transporter, RND family, MFP subunit K07798 cusB; membrane fusion protein, copper/silver efflux system D Hneap_0278 heavy metal efflux pump, CzcA family K07787 cusA; copper/silver efflux system protein D Hneap_0622 flagellin domain protein K02406 fliC; flagellin D Hneap_0717 RNA polymerase, sigma 28 subunit, FliA/WhiG K02405 fliA; RNA polymerase sigma factor FliA D Hneap_1684 MotA/TolQ/ExbB proton channel K02556 motA; chemotaxis protein MotA D Hneap_1035 flagellar motor protein MotA K02556 motA; chemotaxis protein MotA D Hneap_2398 cytochrome oxidase assembly K02259 COX15; heme a synthase [EC:1.17.99.9] D Hneap_0001 chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein D Hneap_2150 signal transduction histidine kinase, LytS K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3] D Hneap_2149 two component transcriptional regulator, LytTR family K08083 algR; two-component system, LytTR family, response regulator AlgR D Hneap_1286 response regulator receiver and Hpt phospho transfer protein K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3] D Hneap_1804 two component transcriptional regulator, LuxR family K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY D Hneap_0359 carbon storage regulator, CsrA K03563 csrA; carbon storage regulator D Hneap_2311 Flp pilus assembly protein CpaB K02279 cpaB; pilus assembly protein CpaB D Hneap_2310 type II and III secretion system protein K02280 cpaC; pilus assembly protein CpaC D Hneap_2309 FHA domain containing protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] D Hneap_2308 Type II secretion system F domain protein K12510 tadB; tight adherence protein B D Hneap_2307 Type II secretion system F domain protein K12511 tadC; tight adherence protein C D Hneap_2147 UTP-GlnB uridylyltransferase, GlnD K00990 glnD; [protein-PII] uridylyltransferase [EC:2.7.7.59] D Hneap_0800 nitrogen regulatory protein P-II K04751 glnB; nitrogen regulatory protein P-II 1 D Hneap_0257 signal transduction histidine kinase, nitrogen specific, NtrB K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3] D Hneap_0256 nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG D Hneap_0209 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_0794 glutamine synthetase, type III K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_2370 glutamine synthetase, type III K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_2380 Glutamate--putrescine ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_2081 multi-sensor signal transduction histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] D Hneap_2080 two component, sigma54 specific, transcriptional regulator, Fis family K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX D Hneap_2207 transcriptional regulator, NifA subfamily, Fis Family K02584 nifA; Nif-specific regulatory protein D Hneap_1585 transcriptional regulator, NifA subfamily, Fis Family K02584 nifA; Nif-specific regulatory protein D Hneap_2100 two component, sigma54 specific, transcriptional regulator, Fis family K07714 atoC; two-component system, NtrC family, response regulator AtoC D Hneap_2070 two component, sigma54 specific, transcriptional regulator, Fis family K07714 atoC; two-component system, NtrC family, response regulator AtoC D Hneap_2270 multi-sensor signal transduction histidine kinase K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3] D Hneap_2269 two component, sigma54 specific, transcriptional regulator, Fis family K02667 pilR; two-component system, NtrC family, response regulator PilR D Hneap_0751 RNA polymerase, sigma54 subunit, RpoN K03092 rpoN; RNA polymerase sigma-54 factor D Hneap_0014 type IV pilin structural subunit K02650 pilA; type IV pilus assembly protein PilA D Hneap_0230 Fimbrial protein pilin K02650 pilA; type IV pilus assembly protein PilA D Hneap_1430 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Hneap_1547 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Hneap_1124 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Hneap_0470 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Hneap_0724 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW D Hneap_0723 hypothetical protein K03408 cheW; purine-binding chemotaxis protein CheW D Hneap_0720 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Hneap_0718 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Hneap_0721 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Hneap_1431 response regulator receiver modulated CheW protein K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV D Hneap_0517 methyl-accepting chemotaxis sensory transducer K02660 pilJ; twitching motility protein PilJ D Hneap_0516 CheW protein K02659 pilI; twitching motility protein PilI D Hneap_0518 CheA signal transduction histidine kinase K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator) D Hneap_0515 response regulator receiver protein K02658 pilH; twitching motility two-component system response regulator PilH D Hneap_0519 hypothetical protein K06598 chpC; chemosensory pili system protein ChpC D Hneap_0134 response regulator receiver protein K11443 divK; two-component system, cell cycle response regulator DivK D Hneap_0431 sigma54 specific transcriptional regulator, Fis family K10941 flrA; sigma-54 dependent transcriptional regulator, flagellar regulatory protein D Hneap_1873 putative transcriptional regulator, Crp/Fnr family K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Hneap_1461 putative transcriptional regulator, Crp/Fnr family K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Hneap_1138 ubiquinol-cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8] D Hneap_1139 Cytochrome b/b6 domain protein K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit D Hneap_1140 cytochrome c1 K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit D Hneap_1880 cytochrome c oxidase, cbb3-type, subunit I K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9] D Hneap_1119 cytochrome c oxidase, cbb3-type, subunit I K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9] D Hneap_1879 cytochrome c oxidase, cbb3-type, subunit II K00405 ccoO; cytochrome c oxidase cbb3-type subunit II D Hneap_1877 cytochrome c oxidase, cbb3-type, subunit III K00406 ccoP; cytochrome c oxidase cbb3-type subunit III D Hneap_1294 cytochrome bd ubiquinol oxidase subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7] D Hneap_1295 cytochrome d ubiquinol oxidase, subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7] D Hneap_0498 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein D Hneap_0762 outer membrane efflux protein K12340 tolC; outer membrane protein D Hneap_1021 outer membrane efflux protein K12340 tolC; outer membrane protein D Hneap_1486 polysaccharide export protein K01991 wza; polysaccharide biosynthesis/export protein D Hneap_1675 protein tyrosine phosphatase K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48] D Hneap_0630 UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D Hneap_0965 Acyl-homoserine-lactone synthase K13061 rhlI; acyl homoserine lactone synthase [EC:2.3.1.184] D Hneap_1541 anti-sigma-28 factor, FlgM K02398 flgM; negative regulator of flagellin synthesis FlgM C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis D Hneap_1138 ubiquinol-cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8] B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:hna02024] D Hneap_2013 RNA chaperone Hfq K03666 hfq; host factor-I protein D Hneap_2109 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Hneap_0526 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D Hneap_0965 Acyl-homoserine-lactone synthase K13061 rhlI; acyl homoserine lactone synthase [EC:2.3.1.184] D Hneap_1733 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D Hneap_1622 P-type conjugative transfer ATPase TrbB K20527 trbB; type IV secretion system protein TrbB [EC:7.4.2.8] D Hneap_1619 Conjugal transfer protein TrbC K20528 trbC; type IV secretion system protein TrbC D Hneap_1618 Conjugal transfer TrbD family protein K20529 trbD; type IV secretion system protein TrbD D Hneap_1617 CagE, TrbE, VirB component of type IV transporter system, conserved region K20530 trbE; type IV secretion system protein TrbE [EC:7.4.2.8] D Hneap_1616 P-type conjugative transfer protein TrbJ K20266 trbJ; type IV secretion system protein TrbJ D Hneap_1614 P-type conjugative transfer protein TrbL K07344 trbL; type IV secretion system protein TrbL D Hneap_1665 Conjugal transfer protein K20531 trbF; type IV secretion system protein TrbF D Hneap_1666 P-type conjugative transfer protein TrbG K20532 trbG; type IV secretion system protein TrbG D Hneap_1667 conjugation TrbI family protein K20533 trbI; type IV secretion system protein TrbI D Hneap_1873 putative transcriptional regulator, Crp/Fnr family K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Hneap_1461 putative transcriptional regulator, Crp/Fnr family K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Hneap_0554 ferric uptake regulator, Fur family K09823 zur; Fur family transcriptional regulator, zinc uptake regulator D Hneap_1869 riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D Hneap_2411 membrane protein insertase, YidC/Oxa1 family domain containing K03217 yidC; YidC/Oxa1 family membrane protein insertase D Hneap_0310 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Hneap_1965 preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Hneap_0343 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Hneap_2183 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Hneap_1999 preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Hneap_1544 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Hneap_2346 protein-export protein SecB K03071 secB; preprotein translocase subunit SecB D Hneap_0384 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis [PATH:hna02030] D Hneap_1547 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Hneap_1124 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Hneap_0470 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Hneap_0720 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Hneap_0724 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW D Hneap_0723 hypothetical protein K03408 cheW; purine-binding chemotaxis protein CheW D Hneap_0718 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Hneap_0719 chemotaxis phosphatase, CheZ K03414 cheZ; chemotaxis protein CheZ D Hneap_0721 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Hneap_1431 response regulator receiver modulated CheW protein K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV D Hneap_1430 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Hneap_0434 flagellar motor switch protein FliG K02410 fliG; flagellar motor switch protein FliG D Hneap_0707 flagellar motor switch protein FliM K02416 fliM; flagellar motor switch protein FliM D Hneap_0708 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Hneap_1684 MotA/TolQ/ExbB proton channel K02556 motA; chemotaxis protein MotA D Hneap_1035 flagellar motor protein MotA K02556 motA; chemotaxis protein MotA D Hneap_1685 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB D Hneap_1036 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB C 02040 Flagellar assembly [PATH:hna02040] D Hneap_0432 flagellar hook-basal body complex subunit FliE K02408 fliE; flagellar hook-basal body complex protein FliE D Hneap_0433 flagellar M-ring protein FliF K02409 fliF; flagellar M-ring protein FliF D Hneap_0434 flagellar motor switch protein FliG K02410 fliG; flagellar motor switch protein FliG D Hneap_0435 Flagellar assembly protein FliH/Type III secretion system HrpE K02411 fliH; flagellar assembly protein FliH D Hneap_0436 flagellar protein export ATPase FliI K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] D Hneap_0437 flagellar FliJ protein K02413 fliJ; flagellar protein FliJ D Hneap_0706 flagellar basal body-associated protein FliL K02415 fliL; flagellar protein FliL D Hneap_0707 flagellar motor switch protein FliM K02416 fliM; flagellar motor switch protein FliM D Hneap_0708 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Hneap_0709 flagellar biosynthetic protein FliO K02418 fliO; flagellar protein FliO/FliZ D Hneap_0710 flagellar biosynthetic protein FliP K02419 fliP; flagellar biosynthesis protein FliP D Hneap_0711 flagellar biosynthetic protein FliQ K02420 fliQ; flagellar biosynthesis protein FliQ D Hneap_0712 flagellar biosynthetic protein FliR K02421 fliR; flagellar biosynthesis protein FliR D Hneap_0713 flagellar biosynthetic protein FlhB K02401 flhB; flagellar biosynthesis protein FlhB D Hneap_1540 flagella basal body P-ring formation protein FlgA K02386 flgA; flagellar basal body P-ring formation protein FlgA D Hneap_1776 flagellar basal-body rod protein FlgB K02387 flgB; flagellar basal-body rod protein FlgB D Hneap_1775 flagellar basal-body rod protein FlgC K02388 flgC; flagellar basal-body rod protein FlgC D Hneap_1774 flagellar hook capping protein K02389 flgD; flagellar basal-body rod modification protein FlgD D Hneap_1773 flagellar hook-basal body protein K02390 flgE; flagellar hook protein FlgE D Hneap_1772 flagellar basal-body rod protein FlgF K02391 flgF; flagellar basal-body rod protein FlgF D Hneap_1771 flagellar basal-body rod protein FlgG K02392 flgG; flagellar basal-body rod protein FlgG D Hneap_1770 flagellar L-ring protein K02393 flgH; flagellar L-ring protein FlgH D Hneap_1769 flagellar P-ring protein K02394 flgI; flagellar P-ring protein FlgI D Hneap_1768 flagellar rod assembly protein/muramidase FlgJ K02395 flgJ; peptidoglycan hydrolase FlgJ D Hneap_1767 flagellar hook-associated protein FlgK K02396 flgK; flagellar hook-associated protein 1 D Hneap_1766 flagellar hook-associated protein 3 K02397 flgL; flagellar hook-associated protein 3 FlgL D Hneap_0622 flagellin domain protein K02406 fliC; flagellin D Hneap_0624 flagellar hook-associated 2 domain protein K02407 fliD; flagellar hook-associated protein 2 D Hneap_0625 flagellar protein FliS K02422 fliS; flagellar secretion chaperone FliS D Hneap_1684 MotA/TolQ/ExbB proton channel K02556 motA; chemotaxis protein MotA D Hneap_1035 flagellar motor protein MotA K02556 motA; chemotaxis protein MotA D Hneap_1685 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB D Hneap_1036 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB D Hneap_1541 anti-sigma-28 factor, FlgM K02398 flgM; negative regulator of flagellin synthesis FlgM D Hneap_0461 RNA polymerase, sigma 70 subunit, RpoD K03086 rpoD; RNA polymerase primary sigma factor D Hneap_0431 sigma54 specific transcriptional regulator, Fis family K10941 flrA; sigma-54 dependent transcriptional regulator, flagellar regulatory protein D Hneap_0751 RNA polymerase, sigma54 subunit, RpoN K03092 rpoN; RNA polymerase sigma-54 factor D Hneap_0717 RNA polymerase, sigma 28 subunit, FliA/WhiG K02405 fliA; RNA polymerase sigma factor FliA C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D Hneap_0970 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Hneap_0664 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism [PATH:hna04980] D Hneap_1076 ATP/cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D Hneap_0657 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance [PATH:hna01501] D Hneap_2276 major facilitator superfamily MFS_1 K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG D Hneap_1398 glycoside hydrolase family 3 domain protein K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] D Hneap_1414 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Hneap_1439 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Hneap_1415 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family K18138 acrB; multidrug efflux pump D Hneap_0498 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein D Hneap_0762 outer membrane efflux protein K12340 tolC; outer membrane protein D Hneap_1021 outer membrane efflux protein K12340 tolC; outer membrane protein D Hneap_1936 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Hneap_1271 penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D Hneap_0444 Peptidoglycan glycosyltransferase K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] C 01502 Vancomycin resistance [PATH:hna01502] D Hneap_0452 D-alanine/D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Hneap_1004 alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D Hneap_2388 alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D Hneap_0446 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D Hneap_0447 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D Hneap_0450 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:hna01503] D Hneap_2016 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D Hneap_0040 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Hneap_1392 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Hneap_2167 DSBA oxidoreductase K03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15] D Hneap_1414 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Hneap_1439 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Hneap_1415 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family K18138 acrB; multidrug efflux pump D Hneap_0498 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein D Hneap_0762 outer membrane efflux protein K12340 tolC; outer membrane protein D Hneap_1021 outer membrane efflux protein K12340 tolC; outer membrane protein D Hneap_1442 acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129] B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:hna01000] C 01001 Protein kinases [BR:hna01001] D Hneap_0158 serine/threonine protein kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] D Hneap_2267 histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D Hneap_0208 integral membrane sensor signal transduction histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3] D Hneap_1993 integral membrane sensor signal transduction histidine kinase K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3] D Hneap_1286 response regulator receiver and Hpt phospho transfer protein K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3] D Hneap_2150 signal transduction histidine kinase, LytS K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3] D Hneap_0257 signal transduction histidine kinase, nitrogen specific, NtrB K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3] D Hneap_2081 multi-sensor signal transduction histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] D Hneap_2270 multi-sensor signal transduction histidine kinase K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3] D Hneap_2069 integral membrane sensor signal transduction histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3] D Hneap_0720 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Hneap_0518 CheA signal transduction histidine kinase K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator) C 01009 Protein phosphatases and associated proteins [BR:hna01009] D Hneap_0414 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D Hneap_2002 Heat shock protein Hsp90-like protein K04079 HSP90A; molecular chaperone HtpG D Hneap_0136 protein serine/threonine phosphatase K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16] C 01002 Peptidases and inhibitors [BR:hna01002] D Hneap_2231 lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] D Hneap_1581 Prepilin peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D Hneap_0610 GMP synthase, large subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Hneap_2381 Gamma-glutamyl-gamma-aminobutyrate hydrolase K07010 K07010; putative glutamine amidotransferase D Hneap_0980 NLP/P60 protein K19303 mepH; murein DD-endopeptidase [EC:3.4.-.-] D Hneap_1153 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D Hneap_2284 Glutamate synthase (ferredoxin) K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D Hneap_1238 glucosamine/fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Hneap_0742 asparagine synthase family amidotransferase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D Hneap_2354 DJ-1 family protein K03152 thiJ; protein deglycase [EC:3.5.1.124] D Hneap_1034 aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] D Hneap_1478 Peptidase M16C associated domain protein K06972 PITRM1; presequence protease [EC:3.4.24.-] D Hneap_0978 Leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D Hneap_2246 succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D Hneap_0866 amidase, hydantoinase/carbamoylase family K02083 allC; allantoate deiminase [EC:3.5.3.9] D Hneap_2146 methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D Hneap_2201 peptidase M24 K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9] D Hneap_0894 peptidase M24 K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] D Hneap_1970 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D Hneap_1051 HtpX domain protein K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D Hneap_1447 membrane-associated zinc metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] D Hneap_0040 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Hneap_1392 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Hneap_1707 peptidase S8 and S53 subtilisin kexin sedolisin K08651 E3.4.21.66; thermitase [EC:3.4.21.66] D Hneap_1267 Beta-lactamase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D Hneap_0401 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] D Hneap_0386 ATP-dependent Clp protease, proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D Hneap_0389 ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] D Hneap_0885 Peptidase S24/S26A/S26B, conserved region K03503 umuD; DNA polymerase V [EC:3.4.21.-] D Hneap_1390 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D Hneap_2074 proline iminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5] D Hneap_2353 carboxyl-terminal protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] D Hneap_1759 signal peptide peptidase SppA, 36K type K04773 sppA; protease IV [EC:3.4.21.-] D Hneap_1897 Peptidase S49 domain protein K04774 sohB; serine protease SohB [EC:3.4.21.-] D Hneap_1323 20S proteasome A and B subunits K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2] D Hneap_0026 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Hneap_0829 Gamma-glutamyltransferase K22602 hpxW; oxamate amidohydrolase [EC:3.5.1.126] D Hneap_1232 peptidase U32 K08303 prtC; U32 family peptidase [EC:3.4.-.-] D Hneap_0882 peptidase U32 K24847 rlhA; 23S rRNA 5-hydroxycytidine C2501 synthase D Hneap_2010 HflC protein K04087 hflC; modulator of FtsH protease HflC D Hneap_2011 HflK protein K04088 hflK; modulator of FtsH protease HflK C 01003 Glycosyltransferases [BR:hna01003] D Hneap_1926 glycosyl transferase group 1 K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D Hneap_0774 glycogen/starch synthase, ADP-glucose type K00703 glgA; starch synthase [EC:2.4.1.21] D Hneap_0231 monofunctional biosynthetic peptidoglycan transglycosylase K03814 mtgA; monofunctional glycosyltransferase [EC:2.4.99.28] D Hneap_0650 penicillin-binding protein 1B K05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4] D Hneap_1936 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Hneap_0580 glucosyltransferase MdoH K03669 mdoH; membrane glycosyltransferase [EC:2.4.1.-] C 01005 Lipopolysaccharide biosynthesis proteins [BR:hna01005] D Hneap_1442 acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129] D Hneap_1224 lipid-A-disaccharide synthase K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182] D Hneap_2001 UDP-3-0-acyl N-acetylglucosamine deacetylase K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108] D Hneap_1444 UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191] D Hneap_1082 UDP-2,3-diacylglucosamine hydrolase K03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54] D Hneap_1727 tetraacyldisaccharide 4'-kinase K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130] D Hneap_2123 lipid A biosynthesis acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-] D Hneap_2076 lipid A biosynthesis acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-] D Hneap_1481 lipid A biosynthesis acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-] D Hneap_2122 Three-deoxy-D-manno-octulosonic-acid transferase domain protein K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15] D Hneap_0663 2-dehydro-3-deoxyphosphooctonate aldolase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55] D Hneap_1725 3-deoxy-D-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38] D Hneap_0755 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45] D Hneap_0756 KpsF/GutQ family protein K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13] D Hneap_1054 hypothetical protein K02841 waaC; lipopolysaccharide heptosyltransferase I [EC:2.4.99.23] D Hneap_0674 phosphoheptose isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28] D Hneap_1526 glycosyl transferase family 2 K20534 gtrB; polyisoprenyl-phosphate glycosyltransferase [EC:2.4.-.-] C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:hna01011] D Hneap_0765 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D Hneap_1055 UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D Hneap_0451 UDP-N-acetylmuramate/alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D Hneap_0448 UDP-N-acetylmuramoylalanine/D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D Hneap_0445 UDP-N-acetylmuramyl-tripeptide synthetase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D Hneap_0452 D-alanine/D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Hneap_1004 alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D Hneap_2388 alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D Hneap_0073 glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D Hneap_2265 glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D Hneap_0447 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D Hneap_0450 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D Hneap_1864 undecaprenol kinase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D Hneap_0139 phosphoesterase PA-phosphatase related protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D Hneap_2245 integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase D Hneap_1936 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Hneap_0650 penicillin-binding protein 1B K05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4] D Hneap_1271 penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D Hneap_0444 Peptidoglycan glycosyltransferase K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D Hneap_1267 Beta-lactamase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D Hneap_0401 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] D Hneap_0231 monofunctional biosynthetic peptidoglycan transglycosylase K03814 mtgA; monofunctional glycosyltransferase [EC:2.4.99.28] D Hneap_0980 NLP/P60 protein K19303 mepH; murein DD-endopeptidase [EC:3.4.-.-] D Hneap_1070 Lytic transglycosylase catalytic K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29] D Hneap_1269 lytic murein transglycosylase B K08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29] D Hneap_1571 Lytic transglycosylase catalytic K08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29] D Hneap_1327 Lytic transglycosylase catalytic K18691 mltF; peptidoglycan lytic transglycosylase F [EC:4.2.2.29] D Hneap_1919 aminodeoxychorismate lyase K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] D Hneap_1268 rare lipoprotein A K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29] D Hneap_2016 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D Hneap_1698 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD K03806 ampD; N-acetyl-anhydromuramoyl-L-alanine amidase [EC:3.5.1.28] C 01004 Lipid biosynthesis proteins [BR:hna01004] D Hneap_1925 malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D Hneap_1806 3-oxoacyl-(acyl-carrier-protein) synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D Hneap_0952 Beta-ketoacyl synthase K18473 fabY; acetoacetyl-[acyl-carrier protein] synthase [EC:2.3.1.180] D Hneap_0983 Beta-ketoacyl synthase K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D Hneap_2239 Beta-ketoacyl synthase K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D Hneap_0062 Beta-ketoacyl synthase K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D Hneap_1922 3-oxoacyl-(acyl-carrier-protein) synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D Hneap_2241 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hneap_1924 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Hneap_0984 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA K01716 fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14] D Hneap_1443 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D Hneap_0392 short-chain dehydrogenase/reductase SDR K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D Hneap_0010 Arylesterase K10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5] D Hneap_2041 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Hneap_1807 fatty acid/phospholipid synthesis protein PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D Hneap_1883 protein of unknown function DUF205 K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D Hneap_2052 phospholipid/glycerol acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 01008 Polyketide biosynthesis proteins [BR:hna01008] D Hneap_0962 Phosphopantetheinyl transferase component of siderophore synthetase-like protein K02362 entD; enterobactin synthetase component D [EC:6.3.2.14 2.7.8.-] C 01006 Prenyltransferases [BR:hna01006] D Hneap_1678 Polyprenyl synthetase K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] D Hneap_0164 Trans-hexaprenyltranstransferase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90] D Hneap_1450 undecaprenyl diphosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D Hneap_1548 squalene/phytoene synthase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32] D Hneap_2014 tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D Hneap_1018 4-hydroxybenzoate polyprenyl transferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] D Hneap_2402 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] C 01007 Amino acid related enzymes [BR:hna01007] D Hneap_0683 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Hneap_1220 glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18] D Hneap_1069 Glutamate--tRNA ligase K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-] D Hneap_2138 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Hneap_2020 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Hneap_1084 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Hneap_2114 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Hneap_1053 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Hneap_2232 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Hneap_1377 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Hneap_1744 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Hneap_0422 lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D Hneap_0475 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Hneap_2195 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Hneap_2050 glycyl-tRNA synthetase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D Hneap_2051 glycyl-tRNA synthetase, beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D Hneap_1560 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Hneap_0635 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Hneap_1320 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Hneap_0357 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Hneap_1316 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Hneap_1315 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Hneap_0353 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Hneap_1394 aminotransferase class I and II K14261 alaC; alanine-synthesizing transaminase [EC:2.6.1.-] D Hneap_0252 succinyldiaminopimelate transaminase K14267 dapC; N-succinyldiaminopimelate aminotransferase [EC:2.6.1.17] D Hneap_0768 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Hneap_1335 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Hneap_2068 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D Hneap_1508 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D Hneap_1077 aminotransferase class I and II K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D Hneap_2367 aminotransferase class-III K00822 E2.6.1.18; beta-alanine--pyruvate transaminase [EC:2.6.1.18] D Hneap_1346 acetylornithine and succinylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Hneap_2371 4-aminobutyrate aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19] D Hneap_2200 2,4-diaminobutyrate 4-transaminase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76] D Hneap_0195 diaminobutyrate/2-oxoglutarate aminotransferase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76] D Hneap_2379 aminotransferase class-III K12256 spuC; putrescine---pyruvate transaminase [EC:2.6.1.113] D Hneap_0419 adenosylmethionine-8-amino-7-oxononanoate aminotransferase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62] D Hneap_1239 glutamate-1-semialdehyde-2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D Hneap_2385 aminotransferase class-III K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D Hneap_1266 aminotransferase class IV K00824 dat; D-alanine transaminase [EC:2.6.1.21] D Hneap_2135 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Hneap_1946 Phosphoserine transaminase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Hneap_1338 phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Hneap_0865 aminotransferase class V K00839 pucG; (S)-ureidoglycine---glyoxylate transaminase [EC:2.6.1.112] D Hneap_0629 DegT/DnrJ/EryC1/StrS aminotransferase K13010 per; perosamine synthetase [EC:2.6.1.102] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins [BR:hna00194] D Hneap_2324 ATP synthase F1, epsilon subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D Hneap_2325 ATP synthase F1, beta subunit K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D Hneap_2326 ATP synthase F1, gamma subunit K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D Hneap_2327 ATP synthase F1, alpha subunit K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D Hneap_2328 ATP synthase F1, delta subunit K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D Hneap_2329 ATP synthase F0, B subunit K02109 ATPF0B; F-type H+-transporting ATPase subunit b D Hneap_2330 ATP synthase F0, C subunit K02110 ATPF0C; F-type H+-transporting ATPase subunit c D Hneap_2331 ATP synthase F0, A subunit K02108 ATPF0A; F-type H+-transporting ATPase subunit a D Hneap_2332 hypothetical protein K02116 atpI; ATP synthase protein I D Hneap_2333 hypothetical protein K02116 atpI; ATP synthase protein I B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:hna03000] D Hneap_2116 transcriptional regulator, AraC family K13652 K13652; AraC family transcriptional regulator D Hneap_2173 transcriptional regulator, LysR family K03576 metR; LysR family transcriptional regulator, regulator for metE and metH D Hneap_2339 transcriptional regulator, LysR family K04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator D Hneap_1091 transcriptional regulator, LysR family K21703 cbbR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator D Hneap_0213 transcriptional regulator, LysR family K21703 cbbR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator D Hneap_1096 transcriptional regulator, LysR family K21703 cbbR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator D Hneap_2365 transcriptional regulator, GntR family K03710 K03710; GntR family transcriptional regulator D Hneap_2382 transcriptional regulator, GntR family with aminotransferase domain K00375 K00375; GntR family transcriptional regulator / MocR family aminotransferase D Hneap_1603 transcriptional regulator, TetR family K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon D Hneap_1699 transcriptional regulator, TetR family K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon D Hneap_1668 hypothetical protein K22105 fabR; TetR/AcrR family transcriptional regulator, fatty acid biosynthesis regulator D Hneap_0165 transcriptional regulator, AsnC family K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein D Hneap_2390 transcriptional regulator, AsnC family K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein D Hneap_0661 transcriptional regulator, MarR family K06075 slyA; MarR family transcriptional regulator, transcriptional regulator for hemolysin D Hneap_1213 transcriptional regulator, MerR family K08365 merR; MerR family transcriptional regulator, mercuric resistance operon regulatory protein D Hneap_1577 transcriptional regulator, MerR family K22491 litR; MerR family transcriptional regulator, light-induced transcriptional regulator D Hneap_0987 ferric uptake regulator, Fur family K03711 fur; Fur family transcriptional regulator, ferric uptake regulator D Hneap_0554 ferric uptake regulator, Fur family K09823 zur; Fur family transcriptional regulator, zinc uptake regulator D Hneap_1873 putative transcriptional regulator, Crp/Fnr family K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Hneap_1461 putative transcriptional regulator, Crp/Fnr family K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Hneap_2189 transcriptional regulator, BadM/Rrf2 family K13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor D Hneap_1302 transcriptional regulator, BadM/Rrf2 family K13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor D Hneap_0930 transcriptional regulator, BadM/Rrf2 family K13771 nsrR; Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor D Hneap_1532 transcriptional regulator, ArsR family K23988 arsR-arsC; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor / arsenate reductase (thioredoxin) [EC:1.20.4.4] D Hneap_1121 iron (metal) dependent repressor, DtxR family K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D Hneap_0307 biotin/acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D Hneap_1692 transcriptional regulator, Fis family K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein D Hneap_0431 sigma54 specific transcriptional regulator, Fis family K10941 flrA; sigma-54 dependent transcriptional regulator, flagellar regulatory protein D Hneap_2207 transcriptional regulator, NifA subfamily, Fis Family K02584 nifA; Nif-specific regulatory protein D Hneap_1585 transcriptional regulator, NifA subfamily, Fis Family K02584 nifA; Nif-specific regulatory protein D Hneap_0810 transcriptional regulator, ModE family K02019 modE; molybdate transport system regulatory protein D Hneap_1405 putative transcriptional regulator, ModE family K02019 modE; molybdate transport system regulatory protein D Hneap_0975 putative transcriptional regulator, XRE family K07727 K07727; putative transcriptional regulator D Hneap_0795 transcriptional regulator NikR, CopG family K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator D Hneap_1626 CopG domain protein DNA-binding domain protein K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB D Hneap_0031 BolA family protein K05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator D Hneap_2334 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Hneap_1670 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Hneap_0639 amino acid-binding ACT domain-containing protein K03567 gcvR; glycine cleavage system transcriptional repressor D Hneap_2032 amino acid-binding ACT domain protein K03567 gcvR; glycine cleavage system transcriptional repressor D Hneap_1354 Uracil phosphoribosyltransferase K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] D Hneap_0482 phage transcriptional regulator, AlpA K07733 alpA; prophage regulatory protein D Hneap_0395 FMN-binding negative transcriptional regulator K07734 paiB; transcriptional regulator D Hneap_1356 protein of unknown function DUF179 K07735 algH; putative transcriptional regulator D Hneap_0509 transcriptional regulator, TraR/DksA family K06204 dksA; RNA polymerase-binding transcription factor D Hneap_1870 ATP-cone domain protein K07738 nrdR; transcriptional repressor NrdR D Hneap_0441 MraZ protein K03925 mraZ; transcriptional regulator MraZ C 03021 Transcription machinery [BR:hna03021] D Hneap_0347 DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D Hneap_0316 DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D Hneap_0317 DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D Hneap_0034 DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D Hneap_0461 RNA polymerase, sigma 70 subunit, RpoD K03086 rpoD; RNA polymerase primary sigma factor D Hneap_1944 RNA polymerase, sigma 70 subunit, RpoD subfamily K03087 rpoS; RNA polymerase nonessential primary-like sigma factor D Hneap_0172 RNA polymerase, sigma-24 subunit, ECF subfamily K03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily D Hneap_0701 RNA polymerase, sigma-24 subunit, ECF subfamily K03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily D Hneap_0570 RNA polymerase, sigma 32 subunit, RpoH K03089 rpoH; RNA polymerase sigma-32 factor D Hneap_0751 RNA polymerase, sigma54 subunit, RpoN K03092 rpoN; RNA polymerase sigma-54 factor D Hneap_0717 RNA polymerase, sigma 28 subunit, FliA/WhiG K02405 fliA; RNA polymerase sigma factor FliA D Hneap_1468 NusA antitermination factor K02600 nusA; transcription termination/antitermination protein NusA D Hneap_1865 NusB antitermination factor K03625 nusB; transcription antitermination protein NusB D Hneap_0311 NusG antitermination factor K02601 nusG; transcription termination/antitermination protein NusG D Hneap_1522 Glutathione S-transferase domain protein K03599 sspA; stringent starvation protein A D Hneap_1521 Stringent starvation protein B K03600 sspB; stringent starvation protein B D Hneap_0704 positive regulator of sigma E, RseC/MucC K03803 rseC; sigma-E factor negative regulatory protein RseC D Hneap_0509 transcriptional regulator, TraR/DksA family K06204 dksA; RNA polymerase-binding transcription factor D Hneap_1561 transcription elongation factor GreA K03624 greA; transcription elongation factor GreA D Hneap_1087 transcription elongation factor GreB K04760 greB; transcription elongation factor GreB D Hneap_2341 transcription termination factor Rho K03628 rho; transcription termination factor Rho C 03019 Messenger RNA biogenesis [BR:hna03019] D Hneap_1756 ribonuclease, Rne/Rng family K08300 rne; ribonuclease E [EC:3.1.26.12] D Hneap_1736 ribonuclease, Rne/Rng family K08301 rng; ribonuclease G [EC:3.1.26.-] D Hneap_1388 ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D Hneap_0351 ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] D Hneap_1566 Exonuclease RNase T and DNA polymerase III K13288 orn; oligoribonuclease [EC:3.1.-.-] D Hneap_1362 DEAD/DEAH box helicase domain protein K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] D Hneap_1927 DEAD/DEAH box helicase domain protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Hneap_0299 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D Hneap_0970 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Hneap_0664 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Hneap_1463 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D Hneap_2341 transcription termination factor Rho K03628 rho; transcription termination factor Rho D Hneap_1472 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK D Hneap_0620 chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Hneap_2013 RNA chaperone Hfq K03666 hfq; host factor-I protein D Hneap_0266 Polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] D Hneap_0972 protein of unknown function DUF344 K22468 ppk2; polyphosphate kinase [EC:2.7.4.34] D Hneap_1131 poly(A) polymerase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] D Hneap_0992 NUDIX hydrolase K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-] D Hneap_0359 carbon storage regulator, CsrA K03563 csrA; carbon storage regulator D Hneap_0867 regulator of ribonuclease activity A K02553 rraA; regulator of ribonuclease activity A D Hneap_0746 conserved hypothetical protein K06958 rapZ; RNase adapter protein RapZ D Hneap_0283 ATP-dependent helicase HrpA K03578 hrpA; ATP-dependent RNA helicase HrpA [EC:5.6.2.6] C 03041 Spliceosome C 03011 Ribosome [BR:hna03011] D Hneap_1330 ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1 D Hneap_1454 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D Hneap_0329 ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D Hneap_0346 ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D Hneap_0340 ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D Hneap_1383 ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D Hneap_0319 ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D Hneap_0337 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D Hneap_2043 ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D Hneap_0322 ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D Hneap_0345 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D Hneap_0318 ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D Hneap_0344 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D Hneap_0336 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D Hneap_1464 ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D Hneap_2006 ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D Hneap_0332 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D Hneap_1382 ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D Hneap_0327 ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D Hneap_2024 ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D Hneap_1931 ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D Hneap_0313 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D Hneap_0326 ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D Hneap_0323 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D Hneap_0324 ribosomal protein L4/L1e K02926 RP-L4; large subunit ribosomal protein L4 D Hneap_0335 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Hneap_0338 ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D Hneap_1381 ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D Hneap_0314 ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D Hneap_0312 ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Hneap_0315 ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D Hneap_2044 ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D Hneap_0333 ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D Hneap_0342 ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D Hneap_0330 ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D Hneap_0348 ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D Hneap_0339 ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D Hneap_2003 ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D Hneap_1317 ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D Hneap_0270 ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D Hneap_0328 ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D Hneap_0325 Ribosomal protein L25/L23 K02892 RP-L23; large subunit ribosomal protein L23 D Hneap_0334 ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D Hneap_0269 ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D Hneap_2021 ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D Hneap_0331 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Hneap_0341 ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D Hneap_2094 ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D Hneap_1808 ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D Hneap_2022 ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D Hneap_2414 ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D Hneap_1318 ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D Hneap_0110 ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 D Hneap_1169 ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 K02897 RP-L25; large subunit ribosomal protein L25 D Hneap_R0020 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Hneap_R0048 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Hneap_R0052 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Hneap_R0016 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Hneap_R0019 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Hneap_R0049 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:hna03009] D Hneap_1388 ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D Hneap_1566 Exonuclease RNase T and DNA polymerase III K13288 orn; oligoribonuclease [EC:3.1.-.-] D Hneap_1387 GTP-binding protein Era K03595 era; GTPase D Hneap_0268 GTP-binding protein Obg/CgtA K03979 obgE; GTPase [EC:3.6.5.-] D Hneap_0509 transcriptional regulator, TraR/DksA family K06204 dksA; RNA polymerase-binding transcription factor D Hneap_1468 NusA antitermination factor K02600 nusA; transcription termination/antitermination protein NusA D Hneap_1865 NusB antitermination factor K03625 nusB; transcription antitermination protein NusB D Hneap_0311 NusG antitermination factor K02601 nusG; transcription termination/antitermination protein NusG D Hneap_1277 dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D Hneap_2178 Fmu (Sun) domain protein K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D Hneap_2083 sun protein K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D Hneap_0553 methyltransferase small K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172] D Hneap_1543 methyltransferase K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171] D Hneap_0420 protein of unknown function DUF558 K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193] D Hneap_2336 methyltransferase GidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D Hneap_0442 S-adenosyl-methyltransferase MraW K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199] D Hneap_0677 Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198] D Hneap_1343 protein of unknown function DUF548 K15984 rsmJ; 16S rRNA (guanine1516-N2)-methyltransferase [EC:2.1.1.242] D Hneap_0352 RNA methyltransferase, TrmH family, group 3 K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185] D Hneap_1971 ribosomal RNA methyltransferase RrmJ/FtsJ K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166] D Hneap_1738 protein of unknown function DUF163 K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177] D Hneap_0027 protein of unknown function DUF519 K07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266] D Hneap_0981 putative RNA methylase K12297 rlmKL; 23S rRNA (guanine2069-N7)-methyltransferase / 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.264 2.1.1.173] D Hneap_2191 radical SAM enzyme, Cfr family K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192] D Hneap_1480 RNA methyltransferase, TrmA family K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190] D Hneap_1713 23S rRNA (uracil-5-)-methyltransferase RumB K03212 rumB; 23S rRNA (uracil747-C5)-methyltransferase [EC:2.1.1.189] D Hneap_2148 pseudouridine synthase K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29] D Hneap_1357 pseudouridine synthase K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22] D Hneap_1757 pseudouridine synthase, RluA family K06179 rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24] D Hneap_2034 pseudouridine synthase, RluA family K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D Hneap_2056 pseudouridine synthase K06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20] D Hneap_1574 ribosomal-protein-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D Hneap_2005 16S rRNA processing protein RimM K02860 rimM; 16S rRNA processing protein RimM D Hneap_1913 MiaB-like tRNA modifying enzyme YliG K14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4] D Hneap_0890 protein of unknown function DUF181 K09136 ycaO; ribosomal protein S12 methylthiotransferase accessory factor D Hneap_1372 ribosomal protein L11 methyltransferase K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-] D Hneap_0597 protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific K07320 prmB; ribosomal protein L3 glutamine methyltransferase [EC:2.1.1.298] D Hneap_1404 Cupin 4 family protein K18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47] D Hneap_1756 ribonuclease, Rne/Rng family K08300 rne; ribonuclease E [EC:3.1.26.12] D Hneap_1736 ribonuclease, Rne/Rng family K08301 rng; ribonuclease G [EC:3.1.26.-] D Hneap_1355 Holliday junction resolvase YqgF K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-] D Hneap_1927 DEAD/DEAH box helicase domain protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Hneap_1568 ribosome small subunit-dependent GTPase A K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D Hneap_2203 ribosome-associated GTPase EngA K03977 engA; GTPase D Hneap_2012 GTP-binding proten HflX K03665 hflX; GTPase D Hneap_2091 SUA5/yciO/yrdC domain protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Hneap_0033 (p)ppGpp synthetase I, SpoT/RelA K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D Hneap_1466 ribosome-binding factor A K02834 rbfA; ribosome-binding factor A D Hneap_1469 protein of unknown function DUF150 K09748 rimP; ribosome maturation factor RimP D Hneap_1739 iojap-like protein K09710 ybeB; ribosome-associated protein D Hneap_1182 protein of unknown function UPF0054 K07042 ybeY; probable rRNA maturation factor D Hneap_1974 protein of unknown function UPF0044 K07574 yhbY; RNA-binding protein D Hneap_1237 protein of unknown function DUF615 K09889 yjgA; ribosome-associated protein D Hneap_0750 sigma54 modulation protein/ribosomal protein S30EA K05808 hpf; ribosome hibernation promoting factor D Hneap_1171 GTP-binding protein YchF K06942 ychF; ribosome-binding ATPase D Hneap_1809 protein of unknown function DUF177 K07040 yceD; DUF177 domain-containing protein C 03016 Transfer RNA biogenesis [BR:hna03016] D Hneap_1695 polynucleotide adenylyltransferase/metal dependent phosphohydrolase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] D Hneap_0683 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Hneap_0635 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Hneap_2232 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Hneap_1744 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Hneap_1053 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Hneap_1220 glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18] D Hneap_2114 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Hneap_0422 lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D Hneap_0475 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Hneap_0357 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Hneap_1320 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Hneap_1560 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Hneap_1084 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Hneap_1377 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Hneap_2195 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Hneap_1316 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Hneap_1315 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Hneap_2138 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Hneap_2020 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Hneap_1569 histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D Hneap_1825 tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] D Hneap_2344 protein of unknown function UPF0066 K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-] D Hneap_1161 tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D Hneap_1465 tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D Hneap_1148 tRNA pseudouridine synthase D TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27] D Hneap_2091 SUA5/yciO/yrdC domain protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Hneap_2014 tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D Hneap_2410 tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-] D Hneap_2337 glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D Hneap_2397 selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3] D Hneap_0525 3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] D Hneap_1501 3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] D Hneap_2413 ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5] D Hneap_R0010 rnpB; RNA component of RNaseP K01978 rnpB; M1 RNA D Hneap_0645 ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-] D Hneap_0507 ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5] D Hneap_1060 ABC transporter related protein K06020 ettA; energy-dependent translational throttle protein EttA D Hneap_2050 glycyl-tRNA synthetase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D Hneap_2051 glycyl-tRNA synthetase, beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D Hneap_1069 Glutamate--tRNA ligase K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-] D Hneap_0612 CMP/dCMP deaminase zinc-binding protein K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33] D Hneap_1185 dihydrouridine synthase DuS K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-] D Hneap_1691 TIM-barrel protein, nifR3 family K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-] D Hneap_1184 tRNA-i(6)A37 thiotransferase enzyme MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3] D Hneap_2395 methyltransferase K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-] D Hneap_2394 methyltransferase K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-] D Hneap_2004 tRNA (guanine-N1)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D Hneap_2187 RNA methyltransferase, TrmH family, group 1 K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200] D Hneap_2343 RNA methyltransferase, TrmH family, group 2 K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207] D Hneap_2148 pseudouridine synthase K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29] D Hneap_1948 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D Hneap_2075 PP-loop domain protein K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA D Hneap_1905 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D Hneap_1198 iron-sulfur cluster assembly accessory protein K13628 iscA; iron-sulfur cluster assembly protein D Hneap_1823 folate-binding protein YgfZ K06980 ygfZ; tRNA-modifying protein YgfZ D Hneap_0743 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-] D Hneap_2181 S-adenosylmethionine/tRNA-ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17] D Hneap_0539 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D Hneap_1680 6-pyruvoyl tetrahydropterin synthase and hypothetical protein K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D Hneap_0538 Radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D Hneap_0160 7-cyano-7-deazaguanine reductase K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13] D Hneap_1030 iron-sulfur cluster binding protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6] D Hneap_2396 tRNA 2-selenouridine synthase K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3] D Hneap_2182 queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29] D Hneap_1136 tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19] D Hneap_0994 peptidase M22 glycoprotease K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB D Hneap_1884 metalloendopeptidase, glycoprotease family K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234] D Hneap_2018 protein of unknown function UPF0079 K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE D Hneap_1693 UBA/THIF-type NAD/FAD binding protein K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase D Hneap_0351 ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] D Hneap_1463 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] C 03012 Translation factors [BR:hna03012] D Hneap_1467 translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D Hneap_1319 translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D Hneap_0167 ABC transporter related protein K06158 ABCF3; ATP-binding cassette, subfamily F, member 3 D Hneap_1453 translation elongation factor Ts K02357 tsf; elongation factor Ts D Hneap_0309 translation elongation factor Tu K02358 tuf; elongation factor Tu D Hneap_0321 translation elongation factor Tu K02358 tuf; elongation factor Tu D Hneap_0320 translation elongation factor G K02355 fusA; elongation factor G D Hneap_1044 peptide chain release factor 1 K02835 prfA; peptide chain release factor 1 D Hneap_1451 ribosome recycling factor K02838 frr; ribosome recycling factor D Hneap_1045 protein-(glutamine-N5) methyltransferase, release factor-specific K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D Hneap_1170 peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D Hneap_1762 translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1 D Hneap_0565 translation elongation factor P K02356 efp; elongation factor P D Hneap_0421 hypothetical protein K02836 prfB; peptide chain release factor 2 D Hneap_1821 peptide chain release factor 3 K02837 prfC; peptide chain release factor 3 D Hneap_0215 Class I peptide chain release factor K15034 yaeJ; ribosome-associated protein C 03110 Chaperones and folding catalysts [BR:hna03110] D Hneap_1761 ATP-dependent Clp protease, ATP-binding subunit clpA K03694 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA D Hneap_2027 ATP-dependent chaperone ClpB K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB D Hneap_0387 ATP-dependent Clp protease, ATP-binding subunit ClpX K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX D Hneap_1324 heat shock protein HslVU, ATPase subunit HslU K03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU D Hneap_2002 Heat shock protein Hsp90-like protein K04079 HSP90A; molecular chaperone HtpG D Hneap_1472 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK D Hneap_0620 chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Hneap_1471 chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ D Hneap_0109 heat shock protein DnaJ domain protein K05516 cbpA; curved DNA-binding protein D Hneap_1243 Hsp33 protein K04083 hslO; molecular chaperone Hsp33 D Hneap_1473 GrpE protein K03687 GRPE; molecular chaperone GrpE D Hneap_0125 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein D Hneap_1368 RNA-binding S4 domain protein K04762 hslR; ribosome-associated heat shock protein Hsp15 D Hneap_0619 chaperonin Cpn10 K04078 groES; chaperonin GroES D Hneap_0040 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Hneap_1392 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Hneap_1970 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D Hneap_2331 ATP synthase F0, A subunit K02108 ATPF0A; F-type H+-transporting ATPase subunit a D Hneap_2346 protein-export protein SecB K03071 secB; preprotein translocase subunit SecB D Hneap_1972 protein of unknown function DUF461 K09796 pccA; periplasmic copper chaperone A D Hneap_1707 peptidase S8 and S53 subtilisin kexin sedolisin K08651 E3.4.21.66; thermitase [EC:3.4.21.66] D Hneap_0508 peptidyl-prolyl cis-trans isomerase cyclophilin type K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] D Hneap_1083 peptidyl-prolyl cis-trans isomerase cyclophilin type K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] D Hneap_0391 PpiC-type peptidyl-prolyl cis-trans isomerase K03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] D Hneap_2230 peptidylprolyl isomerase FKBP-type K03774 slpA; FKBP-type peptidyl-prolyl cis-trans isomerase SlpA [EC:5.2.1.8] D Hneap_0734 peptidylprolyl isomerase FKBP-type K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8] D Hneap_0305 peptidylprolyl isomerase FKBP-type K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8] D Hneap_1460 PpiC-type peptidyl-prolyl cis-trans isomerase K03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8] D Hneap_1275 SurA domain protein K03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8] D Hneap_2340 thioredoxin K03671 TXN; thioredoxin D Hneap_0303 thioredoxin K03671 TXN; thioredoxin D Hneap_1040 Thioredoxin domain protein K03671 TXN; thioredoxin D Hneap_2347 thioredoxin K03672 trxC; thioredoxin 2 [EC:1.8.1.8] D Hneap_1755 thioredoxin K05838 ybbN; putative thioredoxin D Hneap_2348 glutaredoxin 3 K03676 grxC; glutaredoxin 3 D Hneap_1149 glutaredoxin-like protein K07390 grxD; monothiol glutaredoxin D Hneap_2167 DSBA oxidoreductase K03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15] D Hneap_2037 Disulphide bond isomerase, DsbC/G-like protein K03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1] D Hneap_0669 cytochrome c biogenesis protein transmembrane region K04084 dsbD; thioredoxin:protein disulfide reductase [EC:1.8.4.16] D Hneap_2228 hypothetical protein K03805 dsbG; thiol:disulfide interchange protein DsbG D Hneap_1057 hypothetical protein K03805 dsbG; thiol:disulfide interchange protein DsbG C 04131 Membrane trafficking [BR:hna04131] D Hneap_2217 SNARE associated Golgi protein-related protein K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4] D Hneap_2190 Nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Hneap_0408 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Hneap_0406 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Hneap_2002 Heat shock protein Hsp90-like protein K04079 HSP90A; molecular chaperone HtpG C 04121 Ubiquitin system [BR:hna04121] C 03051 Proteasome [BR:hna03051] D Hneap_2002 Heat shock protein Hsp90-like protein K04079 HSP90A; molecular chaperone HtpG C 03032 DNA replication proteins [BR:hna03032] D Hneap_1829 Ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D Hneap_0390 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D Hneap_1314 integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha D Hneap_1329 integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta D Hneap_0001 chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein D Hneap_1003 replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D Hneap_0462 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D Hneap_0025 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Hneap_1650 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Hneap_0583 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Hneap_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Hneap_1378 DNA polymerase III chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] D Hneap_1742 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Hneap_1917 DNA-directed DNA polymerase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Hneap_1410 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Hneap_1827 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Hneap_0769 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Hneap_1223 Ribonuclease H K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Hneap_1688 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Hneap_0163 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Hneap_1631 D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D Hneap_0202 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D Hneap_0729 DnaA regulatory inactivator Hda K10763 hda; DnaA-homolog protein D Hneap_1339 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D Hneap_0004 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D Hneap_1229 DNA topoisomerase IV, A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D Hneap_1753 DNA topoisomerase IV, B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D Hneap_2090 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D Hneap_1612 DNA topoisomerase III K03169 topB; DNA topoisomerase III [EC:5.6.2.1] C 03036 Chromosome and associated proteins [BR:hna03036] D Hneap_1388 ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D Hneap_0439 histone family protein nucleoid-structuring protein H-NS K03746 hns; DNA-binding protein H-NS D Hneap_0390 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D Hneap_1314 integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha D Hneap_1329 integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta D Hneap_0109 heat shock protein DnaJ domain protein K05516 cbpA; curved DNA-binding protein D Hneap_0001 chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein D Hneap_1219 Ferritin Dps family protein K04047 dps; starvation-inducible DNA-binding protein D Hneap_1692 transcriptional regulator, Fis family K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein D Hneap_2013 RNA chaperone Hfq K03666 hfq; host factor-I protein D Hneap_0165 transcriptional regulator, AsnC family K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein D Hneap_2390 transcriptional regulator, AsnC family K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein D Hneap_0161 chromosome segregation protein SMC K03529 smc; chromosome segregation protein D Hneap_1455 chromosome segregation and condensation protein ScpA K05896 scpA; segregation and condensation protein A D Hneap_1016 chromosome segregation and condensation protein, ScpB K06024 scpB; segregation and condensation protein B D Hneap_0454 cell division protein FtsA K03590 ftsA; cell division protein FtsA D Hneap_0665 Septum formation initiator K05589 ftsB; cell division protein FtsB D Hneap_1545 cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein D Hneap_0444 Peptidoglycan glycosyltransferase K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D Hneap_1519 cell divisionFtsK/SpoIIIE K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family D Hneap_0443 cell division protein FtsL K03586 ftsL; cell division protein FtsL D Hneap_0453 cell division protein FtsQ K03589 ftsQ; cell division protein FtsQ D Hneap_0449 cell division protein FtsW K03588 ftsW; cell division protein FtsW D Hneap_1546 protein of unknown function DUF214 K09811 ftsX; cell division transport system permease protein D Hneap_0455 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Hneap_0162 cell division protein ZipA K03528 zipA; cell division protein ZipA D Hneap_0897 protein of unknown function DUF710 K09888 zapA; cell division protein ZapA D Hneap_0656 protein of unknown function DUF1342 K18778 zapD; cell division protein ZapD D Hneap_2359 AFG1-family ATPase K06916 zapE; cell division protein ZapE D Hneap_2016 N-acetylmuramoyl-L-alanine amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D Hneap_1414 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Hneap_1439 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Hneap_0655 septum site-determining protein MinC K03610 minC; septum site-determining protein MinC D Hneap_1364 septum site-determining protein MinD K03609 minD; septum site-determining protein MinD D Hneap_1365 cell division topological specificity factor MinE K03608 minE; cell division topological specificity factor D Hneap_1248 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins D Hneap_1249 rod shape-determining protein MreC K03570 mreC; rod shape-determining protein MreC D Hneap_1250 rod shape-determining protein MreD K03571 mreD; rod shape-determining protein MreD D Hneap_1270 rod shape-determining protein RodA K05837 rodA; rod shape determining protein RodA D Hneap_0722 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Hneap_2335 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Hneap_1669 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Hneap_0912 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Hneap_0255 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Hneap_2334 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Hneap_1670 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Hneap_1229 DNA topoisomerase IV, A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D Hneap_1753 DNA topoisomerase IV, B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D Hneap_2337 glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D Hneap_2336 methyltransferase GidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D Hneap_1322 integrase family protein K03733 xerC; integrase/recombinase XerC D Hneap_2038 tyrosine recombinase XerD K04763 xerD; integrase/recombinase XerD D Hneap_0423 ATPase-like, ParA/MinD K03593 mrp; ATP-binding protein involved in chromosome partitioning D Hneap_2171 ribosome biogenesis GTP-binding protein YsxC K03978 engB; GTP-binding protein C 03400 DNA repair and recombination proteins [BR:hna03400] D Hneap_1928 methylated-DNA/protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D Hneap_0814 Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D Hneap_1306 Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D Hneap_2154 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D Hneap_1851 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D Hneap_1074 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D Hneap_1996 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Hneap_0178 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D Hneap_1235 deoxyribodipyrimidine photolyase-related protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13] D Hneap_1417 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D Hneap_2023 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D Hneap_0007 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D Hneap_0039 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D Hneap_0403 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Hneap_0163 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Hneap_1688 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Hneap_0024 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A D Hneap_0350 excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B D Hneap_1803 excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C D Hneap_1120 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Hneap_0316 DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D Hneap_0317 DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D Hneap_0347 DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D Hneap_0034 DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D Hneap_1978 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D Hneap_0653 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS D Hneap_2015 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL D Hneap_1071 Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1] D Hneap_0428 exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D Hneap_1677 exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D Hneap_0583 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Hneap_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Hneap_1378 DNA polymerase III chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] D Hneap_1742 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Hneap_1917 DNA-directed DNA polymerase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Hneap_1410 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Hneap_1827 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Hneap_0769 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Hneap_0025 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Hneap_1650 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Hneap_1631 D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D Hneap_0202 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D Hneap_1981 exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5] D Hneap_0563 exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5] D Hneap_1980 exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D Hneap_0354 RecA protein K03553 recA; recombination protein RecA D Hneap_0530 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA D Hneap_0531 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D Hneap_0529 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D Hneap_0799 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D Hneap_1778 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms D Hneap_0003 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF D Hneap_0124 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D Hneap_0615 putative transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D Hneap_1386 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) D Hneap_0771 recombination protein RecR K06187 recR; recombination protein RecR D Hneap_1475 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) D Hneap_1033 putative exonuclease RdgC K03554 rdgC; recombination associated protein RdgC D Hneap_0819 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1 D Hneap_1551 protein of unknown function DUF853 NPT hydrolase putative K06915 herA; DNA double-strand break repair helicase HerA and related ATPase D Hneap_1339 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D Hneap_0004 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D Hneap_2090 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D Hneap_0390 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D Hneap_1692 transcriptional regulator, Fis family K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein D Hneap_1314 integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha D Hneap_1329 integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta D Hneap_0299 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D Hneap_0439 histone family protein nucleoid-structuring protein H-NS K03746 hns; DNA-binding protein H-NS D Hneap_0886 DNA-directed DNA polymerase K03502 umuC; DNA polymerase V D Hneap_0885 Peptidase S24/S26A/S26B, conserved region K03503 umuD; DNA polymerase V [EC:3.4.21.-] D Hneap_0355 regulatory protein RecX K03565 recX; regulatory protein D Hneap_1537 UvrD/REP helicase K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4] D Hneap_0648 helicase c2 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D Hneap_1010 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Hneap_1009 Ribonucleoside-diphosphate reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C 03029 Mitochondrial biogenesis [BR:hna03029] D Hneap_1139 Cytochrome b/b6 domain protein K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit D Hneap_1467 translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D Hneap_1319 translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D Hneap_1453 translation elongation factor Ts K02357 tsf; elongation factor Ts D Hneap_0309 translation elongation factor Tu K02358 tuf; elongation factor Tu D Hneap_0321 translation elongation factor Tu K02358 tuf; elongation factor Tu D Hneap_0320 translation elongation factor G K02355 fusA; elongation factor G D Hneap_1387 GTP-binding protein Era K03595 era; GTPase D Hneap_2138 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Hneap_1744 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Hneap_0475 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Hneap_2114 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Hneap_1245 glutamyl-tRNA(Gln) amidotransferase, A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D Hneap_1244 glutamyl-tRNA(Gln) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Hneap_1247 glutamyl-tRNA(Gln) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D Hneap_0025 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Hneap_1650 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Hneap_1446 outer membrane protein assembly complex, YaeT protein K07277 SAM50; outer membrane protein insertion porin family D Hneap_1472 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK D Hneap_1473 GrpE protein K03687 GRPE; molecular chaperone GrpE D Hneap_0620 chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Hneap_0619 chaperonin Cpn10 K04078 groES; chaperonin GroES D Hneap_1471 chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ D Hneap_1149 glutaredoxin-like protein K07390 grxD; monothiol glutaredoxin D Hneap_0423 ATPase-like, ParA/MinD K03593 mrp; ATP-binding protein involved in chromosome partitioning D Hneap_2402 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D Hneap_2398 cytochrome oxidase assembly K02259 COX15; heme a synthase [EC:1.17.99.9] D Hneap_2411 membrane protein insertase, YidC/Oxa1 family domain containing K03217 yidC; YidC/Oxa1 family membrane protein insertase D Hneap_2404 conserved hypothetical protein K14998 SURF1; surfeit locus 1 family protein D Hneap_1973 electron transport protein SCO1/SenC K07152 SCO1; protein SCO1 D Hneap_2400 electron transport protein SCO1/SenC K07152 SCO1; protein SCO1 D Hneap_2002 Heat shock protein Hsp90-like protein K04079 HSP90A; molecular chaperone HtpG B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:hna02000] D Hneap_1728 lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6] D Hneap_1001 ABC transporter related protein K24821 atm1; ATP-binding cassette, subfamily B, heavy metal transporter D Hneap_1293 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC K16012 cydC; ATP-binding cassette, subfamily C, bacterial CydC D Hneap_1292 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD K16013 cydD; ATP-binding cassette, subfamily C, bacterial CydD D Hneap_1179 ABC transporter domain protein K02471 bacA; vitamin B12/bleomycin/antimicrobial peptide transport system ATP-binding/permease protein D Hneap_0568 ABC transporter related protein K15738 uup; ABC transport system ATP-binding/permease protein D Hneap_0809 molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 modA; molybdate transport system substrate-binding protein D Hneap_0808 molybdate ABC transporter, inner membrane subunit K02018 modB; molybdate transport system permease protein D Hneap_0807 molybdate ABC transporter, ATPase subunit K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D Hneap_2206 putative nitrate transporter component, NrtA K15576 nrtA; nitrate/nitrite transport system substrate-binding protein D Hneap_1115 putative nitrate transport protein K15576 nrtA; nitrate/nitrite transport system substrate-binding protein D Hneap_1116 binding-protein-dependent transport systems inner membrane component K15577 nrtB; nitrate/nitrite transport system permease protein D Hneap_2205 nitrate ABC transporter, inner membrane subunit K15577 nrtB; nitrate/nitrite transport system permease protein D Hneap_1117 nitrate ABC transporter, ATPase subunits C and D K15578 nrtC; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4] D Hneap_2204 nitrate ABC transporter, ATPase subunits C and D K15578 nrtC; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4] D Hneap_2377 extracellular solute-binding protein family 1 K11073 potF; putrescine transport system substrate-binding protein D Hneap_2374 binding-protein-dependent transport systems inner membrane component K11074 potI; putrescine transport system permease protein D Hneap_2375 binding-protein-dependent transport systems inner membrane component K11075 potH; putrescine transport system permease protein D Hneap_2376 spermidine/putrescine ABC transporter ATPase subunit K11076 potG; putrescine transport system ATP-binding protein [EC:7.6.2.16] D Hneap_0790 NlpA lipoprotein K02051 ABC.SN.S; NitT/TauT family transport system substrate-binding protein D Hneap_1817 putative lipoprotein K02051 ABC.SN.S; NitT/TauT family transport system substrate-binding protein D Hneap_0791 binding-protein-dependent transport systems inner membrane component K02050 ABC.SN.P; NitT/TauT family transport system permease protein D Hneap_0792 ABC transporter related protein K02049 ABC.SN.A; NitT/TauT family transport system ATP-binding protein D Hneap_0869 basic membrane lipoprotein K07335 bmpA; basic membrane protein A and related proteins D Hneap_0853 basic membrane lipoprotein K07335 bmpA; basic membrane protein A and related proteins D Hneap_0852 inner-membrane translocator K23535 nupB; general nucleoside transport system permease protein D Hneap_0839 inner-membrane translocator K23535 nupB; general nucleoside transport system permease protein D Hneap_0851 inner-membrane translocator K23536 nupC; general nucleoside transport system permease protein D Hneap_0840 inner-membrane translocator K23536 nupC; general nucleoside transport system permease protein D Hneap_0838 ABC transporter related protein K23537 nupA; general nucleoside transport system ATP-binding protein D Hneap_0849 ABC transporter related protein K23537 nupA; general nucleoside transport system ATP-binding protein D Hneap_0121 conserved hypothetical protein K02069 STAR2; UDP-glucose/iron transport system permease protein D Hneap_0122 ABC transporter related protein K02068 STAR1; UDP-glucose/iron transport system ATP-binding protein D Hneap_0761 Mammalian cell entry related domain protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein D Hneap_1360 Mammalian cell entry related domain protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein D Hneap_0760 protein of unknown function DUF140 K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein D Hneap_1358 protein of unknown function DUF140 K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein D Hneap_0759 ABC transporter related protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein D Hneap_1359 ABC transporter related protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein D Hneap_1361 hypothetical protein K18480 linN; cholesterol transport system auxiliary component D Hneap_0763 toluene tolerance family protein K07323 mlaC; phospholipid transport system substrate-binding protein D Hneap_0764 anti-sigma-factor antagonist K07122 mlaB; phospholipid transport system transporter-binding protein D Hneap_1797 phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D Hneap_1796 phosphate ABC transporter, inner membrane subunit PstC K02037 pstC; phosphate transport system permease protein D Hneap_1795 phosphate ABC transporter, inner membrane subunit PstA K02038 pstA; phosphate transport system permease protein D Hneap_1794 phosphate ABC transporter, ATPase subunit K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Hneap_1103 urea ABC transporter, urea binding protein K11959 urtA; urea transport system substrate-binding protein D Hneap_1597 urea ABC transporter, urea binding protein K11959 urtA; urea transport system substrate-binding protein D Hneap_1102 urea ABC transporter, permease protein UrtB K11960 urtB; urea transport system permease protein D Hneap_1596 urea ABC transporter, permease protein UrtB K11960 urtB; urea transport system permease protein D Hneap_1595 urea ABC transporter, permease protein UrtC K11961 urtC; urea transport system permease protein D Hneap_1101 urea ABC transporter, permease protein UrtC K11961 urtC; urea transport system permease protein D Hneap_1100 urea ABC transporter, ATP-binding protein UrtD K11962 urtD; urea transport system ATP-binding protein D Hneap_1594 urea ABC transporter, ATP-binding protein UrtD K11962 urtD; urea transport system ATP-binding protein D Hneap_1099 urea ABC transporter, ATP-binding protein UrtE K11963 urtE; urea transport system ATP-binding protein D Hneap_1593 urea ABC transporter, ATP-binding protein UrtE K11963 urtE; urea transport system ATP-binding protein D Hneap_0873 ABC transporter related protein K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1] D Hneap_0393 extracellular solute-binding protein family 5 K13893 yejA; microcin C transport system substrate-binding protein D Hneap_0396 binding-protein-dependent transport systems inner membrane component K13894 yejB; microcin C transport system permease protein D Hneap_0397 binding-protein-dependent transport systems inner membrane component K13895 yejE; microcin C transport system permease protein D Hneap_0982 ABC transporter related protein K13896 yejF; microcin C transport system ATP-binding protein D Hneap_1015 periplasmic solute binding protein K09815 znuA; zinc transport system substrate-binding protein D Hneap_1013 ABC-3 protein K09816 znuB; zinc transport system permease protein D Hneap_1014 ABC transporter related protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D Hneap_1506 ABC-2 type transporter K09688 kpsM; capsular polysaccharide transport system permease protein D Hneap_1507 lipopolysaccharide biosynthesis protein K10107 kpsE; capsular polysaccharide transport system permease protein D Hneap_1505 ABC transporter related protein K09689 kpsT; capsular polysaccharide transport system ATP-binding protein [EC:7.6.2.12] D Hneap_0486 ABC-2 type transporter K09690 wzm; homopolymeric O-antigen transport system permease protein D Hneap_0487 ABC transporter related protein K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14] D Hneap_1231 permease YjgP/YjgQ family protein K07091 lptF; lipopolysaccharide export system permease protein D Hneap_1230 permease YjgP/YjgQ family protein K11720 lptG; lipopolysaccharide export system permease protein D Hneap_0752 ABC transporter related protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5] D Hneap_2120 ABC-2 type transporter, NodJ family K09694 nodJ; lipooligosaccharide transport system permease protein D Hneap_2121 ABC transporter related protein K09695 nodI; lipooligosaccharide transport system ATP-binding protein D Hneap_0224 lipoprotein releasing system, transmembrane protein, LolC/E family K09808 lolC_E; lipoprotein-releasing system permease protein D Hneap_0225 lipoprotein releasing system, ATP-binding protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] D Hneap_1546 protein of unknown function DUF214 K09811 ftsX; cell division transport system permease protein D Hneap_1545 cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein D Hneap_0881 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D Hneap_0880 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Hneap_0008 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Hneap_0780 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Hneap_0781 ABC transporter related protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Hneap_0009 ABC transporter related protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Hneap_1193 FeS assembly ATPase SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein D Hneap_1831 major facilitator superfamily MFS_1 K05820 hcaT; MFS transporter, PPP family, 3-phenylpropionic acid transporter D Hneap_1534 major facilitator superfamily MFS_1 K25223 arsJ; MFS transporter, APGE family, 1-arseno-3-phosphoglycerate exporter D Hneap_1811 major facilitator superfamily MFS_1 K08227 lplT; MFS transporter, LPLT family, lysophospholipid transporter D Hneap_2276 major facilitator superfamily MFS_1 K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG D Hneap_0527 drug resistance transporter, Bcr/CflA subfamily K07552 bcr; MFS transporter, DHA1 family, multidrug resistance protein D Hneap_0659 drug resistance transporter, EmrB/QacA subfamily K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein D Hneap_0156 major facilitator superfamily MFS_1 K08223 fsr; MFS transporter, FSR family, fosmidomycin resistance protein D Hneap_0993 PTSINtr with GAF domain, PtsP K08484 ptsP; phosphotransferase system, enzyme I, PtsP [EC:2.7.3.9] D Hneap_0744 Phosphotransferase system, phosphocarrier protein HPr K02784 ptsH; phosphocarrier protein HPr D Hneap_0745 PTS system fructose subfamily IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D Hneap_0748 putative PTS IIA-like nitrogen-regulatory protein PtsN K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-] D Hneap_2356 ammonium transporter K03320 amt; ammonium transporter, Amt family D Hneap_0360 ammonium transporter K03320 amt; ammonium transporter, Amt family D Hneap_1522 Glutathione S-transferase domain protein K03599 sspA; stringent starvation protein A D Hneap_0187 von Willebrand factor type A K07114 yfbK; Ca-activated chloride channel homolog D Hneap_0188 Tetratricopeptide TPR_2 repeat protein K07114 yfbK; Ca-activated chloride channel homolog D Hneap_1994 Vault protein inter-alpha-trypsin domain protein K07114 yfbK; Ca-activated chloride channel homolog D Hneap_0466 protein of unknown function UPF0005 K19416 yccA; modulator of FtsH protease D Hneap_1110 formate/nitrite transporter K21993 fdhC; formate transporter D Hneap_1256 large conductance mechanosensitive channel protein K03282 mscL; large conductance mechanosensitive channel D Hneap_1342 MscS Mechanosensitive ion channel K03442 mscS; small conductance mechanosensitive channel D Hneap_1802 MscS Mechanosensitive ion channel K22044 ybiO; moderate conductance mechanosensitive channel D Hneap_1567 magnesium transporter K06213 mgtE; magnesium transporter D Hneap_1684 MotA/TolQ/ExbB proton channel K02556 motA; chemotaxis protein MotA D Hneap_1035 flagellar motor protein MotA K02556 motA; chemotaxis protein MotA D Hneap_1685 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB D Hneap_1036 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB D Hneap_0574 MotA/TolQ/ExbB proton channel K03561 exbB; biopolymer transport protein ExbB D Hneap_2157 tonB-system energizer ExbB K03561 exbB; biopolymer transport protein ExbB D Hneap_1731 MotA/TolQ/ExbB proton channel K03561 exbB; biopolymer transport protein ExbB D Hneap_1730 Biopolymer transport protein ExbD/TolR K03559 exbD; biopolymer transport protein ExbD D Hneap_2158 TonB system transport protein ExbD K03559 exbD; biopolymer transport protein ExbD D Hneap_0573 Biopolymer transport protein ExbD/TolR K03559 exbD; biopolymer transport protein ExbD D Hneap_0533 protein TolQ K03562 tolQ; biopolymer transport protein TolQ D Hneap_0534 protein TolR K03560 tolR; biopolymer transport protein TolR D Hneap_0137 magnesium and cobalt transport protein CorA K03284 corA; magnesium transporter D Hneap_0552 Mg2 transporter protein CorA family protein K16074 zntB; zinc transporter D Hneap_1029 CrcB protein K06199 crcB; fluoride exporter D Hneap_1212 Mercuric transport protein MerT K08363 merT; mercuric ion transport protein D Hneap_1211 mercuric transport protein periplasmic component K08364 merP; periplasmic mercuric ion binding protein D Hneap_0098 putative mercury transport protein MerC K19058 merC; mercuric ion transport protein D Hneap_1210 MerC mercury resistance protein K19058 merC; mercuric ion transport protein D Hneap_1208 MerE family protein K19059 merE; mercuric ion transport protein D Hneap_1777 protein of unknown function DUF21 K03699 tlyC; magnesium and cobalt exporter, CNNM family D Hneap_2060 phosphate-selective porin O and P K07221 oprO_P; phosphate-selective porin OprO and OprP D Hneap_2253 OmpA/MotB domain protein K03286 TC.OOP; OmpA-OmpF porin, OOP family D Hneap_1340 OmpA/MotB domain protein K03286 TC.OOP; OmpA-OmpF porin, OOP family D Hneap_0127 OmpA/MotB domain protein K03286 TC.OOP; OmpA-OmpF porin, OOP family D Hneap_2320 OmpA/MotB domain protein K03286 TC.OOP; OmpA-OmpF porin, OOP family D Hneap_0379 membrane protein involved in aromatic hydrocarbon degradation K06076 fadL; long-chain fatty acid transport protein D Hneap_0576 TonB-dependent siderophore receptor K16090 fiu; catecholate siderophore receptor D Hneap_0521 TonB-dependent receptor K16092 btuB; vitamin B12 transporter D Hneap_2221 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Hneap_1189 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Hneap_0276 outer membrane efflux protein K15725 czcC; outer membrane protein, heavy metal efflux system D Hneap_0786 outer membrane efflux protein K15725 czcC; outer membrane protein, heavy metal efflux system D Hneap_0206 outer membrane efflux protein K15725 czcC; outer membrane protein, heavy metal efflux system D Hneap_0498 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein D Hneap_0762 outer membrane efflux protein K12340 tolC; outer membrane protein D Hneap_1021 outer membrane efflux protein K12340 tolC; outer membrane protein D Hneap_1486 polysaccharide export protein K01991 wza; polysaccharide biosynthesis/export protein D Hneap_0251 Carbohydrate-selective porin OprB K07267 oprB; porin D Hneap_1446 outer membrane protein assembly complex, YaeT protein K07277 SAM50; outer membrane protein insertion porin family D Hneap_2197 outer membrane assembly lipoprotein YfgL K17713 bamB; outer membrane protein assembly factor BamB D Hneap_0679 Uncharacterized lipoprotein-like protein K07287 bamC; outer membrane protein assembly factor BamC D Hneap_2035 outer membrane assembly lipoprotein YfiO K05807 bamD; outer membrane protein assembly factor BamD D Hneap_0986 SmpA/OmlA domain protein K06186 bamE; outer membrane protein assembly factor BamE D Hneap_1752 surface antigen (D15) K07278 tamA; translocation and assembly module TamA D Hneap_1750 protein of unknown function DUF490 K09800 tamB; translocation and assembly module TamB D Hneap_0753 lipopolysaccharide transport periplasmic protein LptA K09774 lptA; lipopolysaccharide export system protein LptA D Hneap_1274 Organic solvent tolerance protein K04744 lptD; LPS-assembly protein D Hneap_1743 putative lipoprotein B precursor K03643 lptE; LPS-assembly lipoprotein D Hneap_1181 CBS domain containing protein K06189 corC; hemolysin (HlyC) family protein D Hneap_0999 cation diffusion facilitator family transporter K16264 czcD; cobalt-zinc-cadmium efflux system protein D Hneap_1177 cation diffusion facilitator family transporter K13283 fieF; ferrous-iron efflux pump FieF D Hneap_0204 heavy metal efflux pump, CzcA family K15726 czcA; heavy metal efflux system protein D Hneap_0278 heavy metal efflux pump, CzcA family K07787 cusA; copper/silver efflux system protein D Hneap_1415 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family K18138 acrB; multidrug efflux pump D Hneap_0154 choline/carnitine/betaine transporter K02168 betT; choline/glycine/proline betaine transport protein D Hneap_0262 C4-dicarboxylate transporter/malic acid transport protein K03304 tehA; tellurite resistance protein D Hneap_0887 SSS sodium solute transporter superfamily K14393 actP; cation/acetate symporter D Hneap_1976 sodium/hydrogen exchanger K03455 KEA1_2_3; K+:H+ antiporter D Hneap_2078 potassium uptake protein, TrkH family K03498 trkH; trk/ktr system potassium uptake protein D Hneap_2079 TrkA-N domain protein K03499 trkA; trk/ktr system potassium uptake protein D Hneap_1591 permease for cytosine/purines uracil thiamine allantoin K10974 codB; cytosine permease D Hneap_2144 Cl-channel voltage-gated family protein K03281 clcA; chloride channel protein, CIC family D Hneap_1261 sulphate transporter K03321 TC.SULP; sulfate permease, SulP family D Hneap_1815 Mn2+/Fe2+ transporter, NRAMP family K03322 mntH; manganese transport protein D Hneap_0427 arsenical pump membrane protein K03893 arsB; arsenical pump membrane protein D Hneap_1130 NADH/Ubiquinone/plastoquinone (complex I) K05559 phaA; multicomponent K+:H+ antiporter subunit A D Hneap_1129 NADH-ubiquinone oxidoreductase chain 4L K05560 phaC; multicomponent K+:H+ antiporter subunit C D Hneap_1128 NADH dehydrogenase (quinone) K05561 phaD; multicomponent K+:H+ antiporter subunit D D Hneap_1127 cation antiporter K05562 phaE; multicomponent K+:H+ antiporter subunit E D Hneap_1126 multiple resistance and pH regulation protein F K05563 phaF; multicomponent K+:H+ antiporter subunit F D Hneap_1125 monovalent cation/proton antiporter, MnhG/PhaG subunit K05564 phaG; multicomponent K+:H+ antiporter subunit G D Hneap_2245 integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase D Hneap_0304 Auxin Efflux Carrier K24180 mleP; malate permease and related proteins D Hneap_0802 protein of unknown function DUF125 transmembrane K22736 VIT; vacuolar iron transporter family protein D Hneap_0571 multiple antibiotic resistance (MarC)-related protein K05595 marC; multiple antibiotic resistance protein D Hneap_0449 cell division protein FtsW K03588 ftsW; cell division protein FtsW D Hneap_0575 TonB family protein K03832 tonB; periplasmic protein TonB D Hneap_2159 TonB family protein K03832 tonB; periplasmic protein TonB D Hneap_0510 TonB family protein K03832 tonB; periplasmic protein TonB D Hneap_0562 peptidoglycan-associated lipoprotein K03640 pal; peptidoglycan-associated lipoprotein D Hneap_0535 protein TolA K03646 tolA; colicin import membrane protein D Hneap_0536 Tol-Pal system beta propeller repeat protein TolB K03641 tolB; TolB protein D Hneap_0660 secretion protein HlyD family protein K03543 emrA; membrane fusion protein, multidrug efflux system D Hneap_0205 efflux transporter, RND family, MFP subunit K15727 czcB; membrane fusion protein, heavy metal efflux system D Hneap_0277 efflux transporter, RND family, MFP subunit K07798 cusB; membrane fusion protein, copper/silver efflux system D Hneap_1163 efflux transporter, RND family, MFP subunit K18302 mexJ; membrane fusion protein, multidrug efflux system D Hneap_1414 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Hneap_1439 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Hneap_0105 FeoA family protein K04758 feoA; ferrous iron transport protein A D Hneap_0106 FeoA family protein K04758 feoA; ferrous iron transport protein A D Hneap_0107 ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B D Hneap_0210 TspO and MBR like protein K05770 TSPO; translocator protein D Hneap_0861 hydroxyisourate hydrolase K07127 uraH; 5-hydroxyisourate hydrolase [EC:3.5.2.17] D Hneap_1413 MltA-interacting MipA family protein K07274 mipA; MipA family protein C 02044 Secretion system [BR:hna02044] D Hneap_0498 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein D Hneap_0762 outer membrane efflux protein K12340 tolC; outer membrane protein D Hneap_1021 outer membrane efflux protein K12340 tolC; outer membrane protein D Hneap_0140 general secretion pathway protein C K02452 gspC; general secretion pathway protein C D Hneap_0141 general secretion pathway protein D K02453 gspD; general secretion pathway protein D D Hneap_0142 general secretory pathway protein E K02454 gspE; general secretion pathway protein E [EC:7.4.2.8] D Hneap_0143 general secretion pathway protein F K02455 gspF; general secretion pathway protein F D Hneap_0144 general secretion pathway protein G K02456 gspG; general secretion pathway protein G D Hneap_0146 general secretion pathway protein I K02458 gspI; general secretion pathway protein I D Hneap_0147 general secretion pathway protein J K02459 gspJ; general secretion pathway protein J D Hneap_0148 General secretion pathway protein K K02460 gspK; general secretion pathway protein K D Hneap_0149 Type II secretory pathway component PulL-like protein K02461 gspL; general secretion pathway protein L D Hneap_0150 General secretion pathway M protein K02462 gspM; general secretion pathway protein M D Hneap_0151 type II secretion system protein N K02463 gspN; general secretion pathway protein N D Hneap_1581 Prepilin peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D Hneap_0014 type IV pilin structural subunit K02650 pilA; type IV pilus assembly protein PilA D Hneap_0230 Fimbrial protein pilin K02650 pilA; type IV pilus assembly protein PilA D Hneap_1579 type IV-A pilus assembly ATPase PilB K02652 pilB; type IV pilus assembly protein PilB D Hneap_1580 Type II secretion system F domain protein K02653 pilC; type IV pilus assembly protein PilC D Hneap_0020 PilE protein K02655 pilE; type IV pilus assembly protein PilE D Hneap_2192 type IV pilus biogenesis/stability protein PilW K02656 pilF; type IV pilus assembly protein PilF D Hneap_0515 response regulator receiver protein K02658 pilH; twitching motility two-component system response regulator PilH D Hneap_0516 CheW protein K02659 pilI; twitching motility protein PilI D Hneap_0517 methyl-accepting chemotaxis sensory transducer K02660 pilJ; twitching motility protein PilJ D Hneap_1937 type IV pilus assembly protein PilM K02662 pilM; type IV pilus assembly protein PilM D Hneap_1938 Fimbrial assembly family protein K02663 pilN; type IV pilus assembly protein PilN D Hneap_1939 Pilus assembly protein PilO K02664 pilO; type IV pilus assembly protein PilO D Hneap_1940 Pilus assembly protein PilP K02665 pilP; type IV pilus assembly protein PilP D Hneap_1941 type IV pilus secretin PilQ K02666 pilQ; type IV pilus assembly protein PilQ D Hneap_1841 twitching motility protein K02669 pilT; twitching motility protein PilT D Hneap_1842 twitching motility protein K02670 pilU; twitching motility protein PilU D Hneap_1843 twitching motility protein K02670 pilU; twitching motility protein PilU D Hneap_0016 type IV pilus modification protein PilV K02671 pilV; type IV pilus assembly protein PilV D Hneap_0017 conserved hypothetical protein K02672 pilW; type IV pilus assembly protein PilW D Hneap_0018 putative Tfp pilus assembly protein K02673 pilX; type IV pilus assembly protein PilX D Hneap_0019 putative type 4 fimbrial biogenesis protein PilY1 K02674 pilY1; type IV pilus assembly protein PilY1 D Hneap_1144 type IV pilus assembly PilZ K02676 pilZ; type IV pilus assembly protein PilZ D Hneap_0015 Tfp pilus assembly protein FimT-like protein K08084 fimT; type IV fimbrial biogenesis protein FimT D Hneap_0021 putative type-4 fimbrial pilin related signal peptide protein K08084 fimT; type IV fimbrial biogenesis protein FimT D Hneap_1714 FimV N-terminal domain protein K08086 fimV; pilus assembly protein FimV D Hneap_2311 Flp pilus assembly protein CpaB K02279 cpaB; pilus assembly protein CpaB D Hneap_2310 type II and III secretion system protein K02280 cpaC; pilus assembly protein CpaC D Hneap_2309 FHA domain containing protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] D Hneap_2308 Type II secretion system F domain protein K12510 tadB; tight adherence protein B D Hneap_2307 Type II secretion system F domain protein K12511 tadC; tight adherence protein C D Hneap_1838 protein of unknown function YGGT K02221 yggT; YggT family protein D Hneap_2137 competence protein ComEA helix-hairpin-helix repeat protein K02237 comEA; competence protein ComEA D Hneap_1429 DNA internalization-related competence protein ComEC/Rec2 K02238 comEC; competence protein ComEC D Hneap_0713 flagellar biosynthetic protein FlhB K02401 flhB; flagellar biosynthesis protein FlhB D Hneap_0429 cytoplasmic domain of flagellar protein FhlB-like protein K04061 flhB2; flagellar biosynthesis protein D Hneap_0433 flagellar M-ring protein FliF K02409 fliF; flagellar M-ring protein FliF D Hneap_0435 Flagellar assembly protein FliH/Type III secretion system HrpE K02411 fliH; flagellar assembly protein FliH D Hneap_0436 flagellar protein export ATPase FliI K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] D Hneap_0708 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Hneap_0709 flagellar biosynthetic protein FliO K02418 fliO; flagellar protein FliO/FliZ D Hneap_0710 flagellar biosynthetic protein FliP K02419 fliP; flagellar biosynthesis protein FliP D Hneap_0711 flagellar biosynthetic protein FliQ K02420 fliQ; flagellar biosynthesis protein FliQ D Hneap_0712 flagellar biosynthetic protein FliR K02421 fliR; flagellar biosynthesis protein FliR D Hneap_1609 Lytic transglycosylase catalytic K03194 virB1; type IV secretion system protein VirB1 D Hneap_1649 TRAG family protein K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8] D Hneap_2037 Disulphide bond isomerase, DsbC/G-like protein K03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1] D Hneap_1622 P-type conjugative transfer ATPase TrbB K20527 trbB; type IV secretion system protein TrbB [EC:7.4.2.8] D Hneap_1619 Conjugal transfer protein TrbC K20528 trbC; type IV secretion system protein TrbC D Hneap_1618 Conjugal transfer TrbD family protein K20529 trbD; type IV secretion system protein TrbD D Hneap_1617 CagE, TrbE, VirB component of type IV transporter system, conserved region K20530 trbE; type IV secretion system protein TrbE [EC:7.4.2.8] D Hneap_1665 Conjugal transfer protein K20531 trbF; type IV secretion system protein TrbF D Hneap_1666 P-type conjugative transfer protein TrbG K20532 trbG; type IV secretion system protein TrbG D Hneap_1667 conjugation TrbI family protein K20533 trbI; type IV secretion system protein TrbI D Hneap_1616 P-type conjugative transfer protein TrbJ K20266 trbJ; type IV secretion system protein TrbJ D Hneap_1614 P-type conjugative transfer protein TrbL K07344 trbL; type IV secretion system protein TrbL D Hneap_1999 preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Hneap_2346 protein-export protein SecB K03071 secB; preprotein translocase subunit SecB D Hneap_2184 protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD D Hneap_0310 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Hneap_2185 protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF D Hneap_1965 preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Hneap_0343 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Hneap_0384 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Hneap_1544 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Hneap_2183 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Hneap_2411 membrane protein insertase, YidC/Oxa1 family domain containing K03217 yidC; YidC/Oxa1 family membrane protein insertase D Hneap_0117 twin-arginine translocation protein, TatA/E family subunit K03116 tatA; sec-independent protein translocase protein TatA D Hneap_0118 twin-arginine translocation protein, TatB subunit K03117 tatB; sec-independent protein translocase protein TatB D Hneap_0119 Sec-independent protein translocase, TatC subunit K03118 tatC; sec-independent protein translocase protein TatC C 02042 Bacterial toxins [BR:hna02042] D Hneap_1777 protein of unknown function DUF21 K03699 tlyC; magnesium and cobalt exporter, CNNM family C 02022 Two-component system [BR:hna02022] D Hneap_2267 histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D Hneap_2266 two component transcriptional regulator PhoB, winged helix family K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB D Hneap_0208 integral membrane sensor signal transduction histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3] D Hneap_0207 two component transcriptional regulator, winged helix family K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR D Hneap_1993 integral membrane sensor signal transduction histidine kinase K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3] D Hneap_1992 two component transcriptional regulator, winged helix family K07663 creB; two-component system, OmpR family, catabolic regulation response regulator CreB D Hneap_0785 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator D Hneap_1813 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator D Hneap_1286 response regulator receiver and Hpt phospho transfer protein K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3] D Hneap_1804 two component transcriptional regulator, LuxR family K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY D Hneap_2150 signal transduction histidine kinase, LytS K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3] D Hneap_2149 two component transcriptional regulator, LytTR family K08083 algR; two-component system, LytTR family, response regulator AlgR D Hneap_0257 signal transduction histidine kinase, nitrogen specific, NtrB K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3] D Hneap_0256 nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG D Hneap_2081 multi-sensor signal transduction histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] D Hneap_2080 two component, sigma54 specific, transcriptional regulator, Fis family K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX D Hneap_2100 two component, sigma54 specific, transcriptional regulator, Fis family K07714 atoC; two-component system, NtrC family, response regulator AtoC D Hneap_2070 two component, sigma54 specific, transcriptional regulator, Fis family K07714 atoC; two-component system, NtrC family, response regulator AtoC D Hneap_2270 multi-sensor signal transduction histidine kinase K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3] D Hneap_2269 two component, sigma54 specific, transcriptional regulator, Fis family K02667 pilR; two-component system, NtrC family, response regulator PilR D Hneap_2069 integral membrane sensor signal transduction histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3] D Hneap_0720 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Hneap_0718 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Hneap_0721 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Hneap_1431 response regulator receiver modulated CheW protein K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV D Hneap_0518 CheA signal transduction histidine kinase K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator) D Hneap_0515 response regulator receiver protein K02658 pilH; twitching motility two-component system response regulator PilH D Hneap_0134 response regulator receiver protein K11443 divK; two-component system, cell cycle response regulator DivK C 02035 Bacterial motility proteins [BR:hna02035] D Hneap_0720 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Hneap_0724 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW D Hneap_0723 hypothetical protein K03408 cheW; purine-binding chemotaxis protein CheW D Hneap_1430 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Hneap_0721 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Hneap_0718 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Hneap_0719 chemotaxis phosphatase, CheZ K03414 cheZ; chemotaxis protein CheZ D Hneap_1431 response regulator receiver modulated CheW protein K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV D Hneap_1547 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Hneap_1124 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Hneap_0470 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Hneap_0435 Flagellar assembly protein FliH/Type III secretion system HrpE K02411 fliH; flagellar assembly protein FliH D Hneap_0436 flagellar protein export ATPase FliI K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] D Hneap_0437 flagellar FliJ protein K02413 fliJ; flagellar protein FliJ D Hneap_0709 flagellar biosynthetic protein FliO K02418 fliO; flagellar protein FliO/FliZ D Hneap_0710 flagellar biosynthetic protein FliP K02419 fliP; flagellar biosynthesis protein FliP D Hneap_0711 flagellar biosynthetic protein FliQ K02420 fliQ; flagellar biosynthesis protein FliQ D Hneap_0712 flagellar biosynthetic protein FliR K02421 fliR; flagellar biosynthesis protein FliR D Hneap_0713 flagellar biosynthetic protein FlhB K02401 flhB; flagellar biosynthesis protein FlhB D Hneap_0434 flagellar motor switch protein FliG K02410 fliG; flagellar motor switch protein FliG D Hneap_0707 flagellar motor switch protein FliM K02416 fliM; flagellar motor switch protein FliM D Hneap_0708 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Hneap_0433 flagellar M-ring protein FliF K02409 fliF; flagellar M-ring protein FliF D Hneap_1769 flagellar P-ring protein K02394 flgI; flagellar P-ring protein FlgI D Hneap_1540 flagella basal body P-ring formation protein FlgA K02386 flgA; flagellar basal body P-ring formation protein FlgA D Hneap_1770 flagellar L-ring protein K02393 flgH; flagellar L-ring protein FlgH D Hneap_0706 flagellar basal body-associated protein FliL K02415 fliL; flagellar protein FliL D Hneap_0432 flagellar hook-basal body complex subunit FliE K02408 fliE; flagellar hook-basal body complex protein FliE D Hneap_1776 flagellar basal-body rod protein FlgB K02387 flgB; flagellar basal-body rod protein FlgB D Hneap_1775 flagellar basal-body rod protein FlgC K02388 flgC; flagellar basal-body rod protein FlgC D Hneap_1774 flagellar hook capping protein K02389 flgD; flagellar basal-body rod modification protein FlgD D Hneap_1772 flagellar basal-body rod protein FlgF K02391 flgF; flagellar basal-body rod protein FlgF D Hneap_1771 flagellar basal-body rod protein FlgG K02392 flgG; flagellar basal-body rod protein FlgG D Hneap_1768 flagellar rod assembly protein/muramidase FlgJ K02395 flgJ; peptidoglycan hydrolase FlgJ D Hneap_1773 flagellar hook-basal body protein K02390 flgE; flagellar hook protein FlgE D Hneap_1767 flagellar hook-associated protein FlgK K02396 flgK; flagellar hook-associated protein 1 D Hneap_1766 flagellar hook-associated protein 3 K02397 flgL; flagellar hook-associated protein 3 FlgL D Hneap_0622 flagellin domain protein K02406 fliC; flagellin D Hneap_0624 flagellar hook-associated 2 domain protein K02407 fliD; flagellar hook-associated protein 2 D Hneap_0625 flagellar protein FliS K02422 fliS; flagellar secretion chaperone FliS D Hneap_0717 RNA polymerase, sigma 28 subunit, FliA/WhiG K02405 fliA; RNA polymerase sigma factor FliA D Hneap_1684 MotA/TolQ/ExbB proton channel K02556 motA; chemotaxis protein MotA D Hneap_1035 flagellar motor protein MotA K02556 motA; chemotaxis protein MotA D Hneap_1685 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB D Hneap_1036 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB D Hneap_0431 sigma54 specific transcriptional regulator, Fis family K10941 flrA; sigma-54 dependent transcriptional regulator, flagellar regulatory protein D Hneap_1541 anti-sigma-28 factor, FlgM K02398 flgM; negative regulator of flagellin synthesis FlgM D Hneap_0623 flagellar protein FlaG protein K06603 flaG; flagellar protein FlaG D Hneap_0715 flagellar biosynthetic protein FlhF K02404 flhF; flagellar biosynthesis protein FlhF D Hneap_0716 Cobyrinic acid ac-diamide synthase K04562 flhG; flagellar biosynthesis protein FlhG D Hneap_0515 response regulator receiver protein K02658 pilH; twitching motility two-component system response regulator PilH D Hneap_0516 CheW protein K02659 pilI; twitching motility protein PilI D Hneap_0517 methyl-accepting chemotaxis sensory transducer K02660 pilJ; twitching motility protein PilJ D Hneap_0518 CheA signal transduction histidine kinase K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator) D Hneap_2269 two component, sigma54 specific, transcriptional regulator, Fis family K02667 pilR; two-component system, NtrC family, response regulator PilR D Hneap_2270 multi-sensor signal transduction histidine kinase K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3] D Hneap_1841 twitching motility protein K02669 pilT; twitching motility protein PilT D Hneap_1842 twitching motility protein K02670 pilU; twitching motility protein PilU D Hneap_1843 twitching motility protein K02670 pilU; twitching motility protein PilU D Hneap_0519 hypothetical protein K06598 chpC; chemosensory pili system protein ChpC D Hneap_0014 type IV pilin structural subunit K02650 pilA; type IV pilus assembly protein PilA D Hneap_0230 Fimbrial protein pilin K02650 pilA; type IV pilus assembly protein PilA D Hneap_1579 type IV-A pilus assembly ATPase PilB K02652 pilB; type IV pilus assembly protein PilB D Hneap_1580 Type II secretion system F domain protein K02653 pilC; type IV pilus assembly protein PilC D Hneap_1581 Prepilin peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D Hneap_2192 type IV pilus biogenesis/stability protein PilW K02656 pilF; type IV pilus assembly protein PilF D Hneap_1941 type IV pilus secretin PilQ K02666 pilQ; type IV pilus assembly protein PilQ D Hneap_1940 Pilus assembly protein PilP K02665 pilP; type IV pilus assembly protein PilP D Hneap_1939 Pilus assembly protein PilO K02664 pilO; type IV pilus assembly protein PilO D Hneap_1938 Fimbrial assembly family protein K02663 pilN; type IV pilus assembly protein PilN D Hneap_1937 type IV pilus assembly protein PilM K02662 pilM; type IV pilus assembly protein PilM D Hneap_1144 type IV pilus assembly PilZ K02676 pilZ; type IV pilus assembly protein PilZ D Hneap_0016 type IV pilus modification protein PilV K02671 pilV; type IV pilus assembly protein PilV D Hneap_0017 conserved hypothetical protein K02672 pilW; type IV pilus assembly protein PilW D Hneap_0018 putative Tfp pilus assembly protein K02673 pilX; type IV pilus assembly protein PilX D Hneap_0019 putative type 4 fimbrial biogenesis protein PilY1 K02674 pilY1; type IV pilus assembly protein PilY1 D Hneap_0020 PilE protein K02655 pilE; type IV pilus assembly protein PilE D Hneap_2311 Flp pilus assembly protein CpaB K02279 cpaB; pilus assembly protein CpaB D Hneap_2310 type II and III secretion system protein K02280 cpaC; pilus assembly protein CpaC D Hneap_2309 FHA domain containing protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:hna04812] D Hneap_1248 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins D Hneap_0455 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Hneap_0454 cell division protein FtsA K03590 ftsA; cell division protein FtsA D Hneap_0655 septum site-determining protein MinC K03610 minC; septum site-determining protein MinC D Hneap_1364 septum site-determining protein MinD K03609 minD; septum site-determining protein MinD D Hneap_1365 cell division topological specificity factor MinE K03608 minE; cell division topological specificity factor D Hneap_0722 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Hneap_2335 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Hneap_1669 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Hneap_0912 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Hneap_0255 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Hneap_2334 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Hneap_1670 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein C 04147 Exosome [BR:hna04147] D Hneap_2002 Heat shock protein Hsp90-like protein K04079 HSP90A; molecular chaperone HtpG D Hneap_0970 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Hneap_0664 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Hneap_0408 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Hneap_0407 Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Hneap_0406 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Hneap_1056 Peroxiredoxin K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24] D Hneap_0620 chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Hneap_1472 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK D Hneap_0995 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Hneap_0609 inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D Hneap_0309 translation elongation factor Tu K02358 tuf; elongation factor Tu D Hneap_0321 translation elongation factor Tu K02358 tuf; elongation factor Tu D Hneap_1569 histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D Hneap_0414 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D Hneap_1273 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Hneap_0544 Adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Hneap_2151 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Hneap_0680 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Hneap_1859 Inositol phosphatase/fructose-16-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D Hneap_0775 1,4-alpha-glucan branching enzyme K00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18] D Hneap_1000 glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D Hneap_0209 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_0794 glutamine synthetase, type III K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_2370 glutamine synthetase, type III K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_2380 Glutamate--putrescine ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Hneap_1172 Porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D Hneap_0029 Ketohexokinase K00846 KHK; ketohexokinase [EC:2.7.1.3] D Hneap_0913 conserved hypothetical protein K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] D Hneap_1337 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Hneap_0052 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D Hneap_1554 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Hneap_0996 glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D Hneap_1966 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 02048 Prokaryotic defense system [BR:hna02048] D Hneap_0819 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1 D Hneap_0818 CRISPR-associated protein Cas2 K09951 cas2; CRISPR-associated protein Cas2 D Hneap_0826 CRISPR-associated helicase Cas3 K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] D Hneap_0822 CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] D Hneap_0824 CRISPR-associated protein, Csd1 family K19117 csd1; CRISPR-associated protein Csd1 D Hneap_0823 CRISPR-associated protein, Csd2 family K19118 csd2; CRISPR-associated protein Csd2 D Hneap_0825 CRISPR-associated protein Cas5 family K19119 cas5d; CRISPR-associated protein Cas5d D Hneap_0616 Type I site-specific deoxyribonuclease K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D Hneap_0614 restriction modification system DNA specificity domain protein K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D Hneap_0613 Site-specific DNA-methyltransferase (adenine-specific) K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D Hneap_1631 D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D Hneap_0202 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D Hneap_0821 transcriptional modulator of MazE/toxin, MazF K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] D Hneap_1625 addiction module toxin, RelE/StbE family K06218 relE; mRNA interferase RelE/StbE D Hneap_0244 addiction module toxin, RelE/StbE family K06218 relE; mRNA interferase RelE/StbE D Hneap_1626 CopG domain protein DNA-binding domain protein K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB D Hneap_0245 prevent-host-death family protein K18923 stbD; antitoxin StbD D Hneap_0246 addiction module toxin, Txe/YoeB family K19158 yoeB; toxin YoeB [EC:3.1.-.-] D Hneap_0074 addiction module toxin, Txe/YoeB family K19158 yoeB; toxin YoeB [EC:3.1.-.-] D Hneap_0247 prevent-host-death family protein K19159 yefM; antitoxin YefM D Hneap_0075 prevent-host-death family protein K19159 yefM; antitoxin YefM D Hneap_0286 plasmid stabilization system K19092 parE1_3_4; toxin ParE1/3/4 D Hneap_0287 putative addiction module antidote protein, CopG/Arc/MetJ family K07746 parD1_3_4; antitoxin ParD1/3/4 D Hneap_1982 death-on-curing family protein K07341 doc; death on curing protein D Hneap_0372 plasmid maintenance system antidote protein, XRE family K21498 higA-1; antitoxin HigA-1 D Hneap_1633 plasmid maintenance system antidote protein, XRE family K21498 higA-1; antitoxin HigA-1 D Hneap_0827 putative plasmid maintenance system antidote protein, XRE family K21498 higA-1; antitoxin HigA-1 D Hneap_0455 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Hneap_1248 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins D Hneap_1229 DNA topoisomerase IV, A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D Hneap_1753 DNA topoisomerase IV, B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D Hneap_0683 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Hneap_2360 protein of unknown function DUF339 K09159 cptB; antitoxin CptB C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules [BR:hna04090] C 01504 Antimicrobial resistance genes [BR:hna01504] D Hneap_1653 Dihydrofolate reductase K18590 dfrA12; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3] D Hneap_1414 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Hneap_1439 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Hneap_1415 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family K18138 acrB; multidrug efflux pump D Hneap_1163 efflux transporter, RND family, MFP subunit K18302 mexJ; membrane fusion protein, multidrug efflux system D Hneap_0498 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein D Hneap_0762 outer membrane efflux protein K12340 tolC; outer membrane protein D Hneap_1021 outer membrane efflux protein K12340 tolC; outer membrane protein C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins [BR:hna00536] D Hneap_0370 filamentous hemagglutinin family outer membrane protein K15125 fhaB; filamentous hemagglutinin D Hneap_0366 protein of unknown function DUF637 hemagglutinin putative K15125 fhaB; filamentous hemagglutinin C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:hna03100] D Hneap_R0021 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Hneap_R0018 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Hneap_R0050 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Hneap_R0031 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hneap_R0033 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hneap_R0039 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hneap_R0023 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Hneap_R0040 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Hneap_R0014 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Hneap_R0044 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Hneap_R0041 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Hneap_R0037 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Hneap_R0038 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Hneap_R0012 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Hneap_R0043 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Hneap_R0005 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Hneap_R0028 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Hneap_R0034 tRNA-His K14226 tRNA-His; tRNA His D Hneap_R0017 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Hneap_R0051 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Hneap_R0009 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hneap_R0027 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hneap_R0042 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hneap_R0047 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hneap_R0030 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Hneap_R0015 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Hneap_R0011 tRNA-Met K14230 tRNA-Met; tRNA Met D Hneap_R0035 tRNA-Met K14230 tRNA-Met; tRNA Met D Hneap_R0036 tRNA-Met K14230 tRNA-Met; tRNA Met D Hneap_R0001 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Hneap_R0029 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Hneap_R0002 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Hneap_R0032 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Hneap_R0022 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Hneap_R0008 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Hneap_R0046 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Hneap_R0006 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Hneap_R0045 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Hneap_R0003 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Hneap_R0007 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Hneap_R0004 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Hneap_R0026 tRNA-Val K14237 tRNA-Val; tRNA Val D Hneap_R0013 tRNA-Val K14237 tRNA-Val; tRNA Val D Hneap_R0052 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Hneap_R0016 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Hneap_R0019 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Hneap_R0049 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Hneap_R0020 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Hneap_R0048 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Hneap_R0025 ffs; SRP RNA; RNA component of signal recognition particle K01983 ffs; SRP RNA D Hneap_R0010 rnpB; RNA component of RNaseP K01978 rnpB; M1 RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D Hneap_1533 glyceraldehyde-3-phosphate dehydrogenase, type I K25224 gapdh; glyceraldehyde-3-phosphate dehydrogenase (arsenate-transferring) [EC:1.2.1.107] D Hneap_1476 cytochrome c class I K19713 tsdA; thiosulfate dehydrogenase [EC:1.8.2.2] D Hneap_2272 peptide methionine sulfoxide reductase K12267 msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12] D Hneap_1255 alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D Hneap_0640 alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D Hneap_0425 Redoxin domain protein K11065 tpx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D Hneap_1025 Pirin domain protein K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24] D Hneap_0955 Taurine catabolism dioxygenase TauD/TfdA K25987 scoE; (R)-3-[(carboxymethyl)amino]fatty acid dioxygenase/decarboxylase [EC:1.14.11.78] D Hneap_0577 2OG-Fe(II) oxygenase K07336 K07336; PKHD-type hydroxylase [EC:1.14.11.-] D Hneap_2226 conserved hypothetical protein K05919 dfx; superoxide reductase [EC:1.15.1.2] D Hneap_1209 mercuric reductase K00520 merA; mercuric reductase [EC:1.16.1.1] D Hneap_1788 NADH/Ubiquinone/plastoquinone (complex I) K12137 hyfB; hydrogenase-4 component B [EC:1.-.-.-] D Hneap_1792 hydrogenase 4 membrane component (E) K12140 hyfE; hydrogenase-4 component E [EC:1.-.-.-] D Hneap_1791 NADH/Ubiquinone/plastoquinone (complex I) K12141 hyfF; hydrogenase-4 component F [EC:1.-.-.-] D Hneap_1789 NADH ubiquinone oxidoreductase 20 kDa subunit K12144 hyfI; hydrogenase-4 component I [EC:1.-.-.-] D Hneap_0499 Protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] D Hneap_0547 protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] D Hneap_1527 Cyclopropane-fatty-acyl-phospholipid synthase K00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79] D Hneap_1892 Cyclopropane-fatty-acyl-phospholipid synthase K00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79] D Hneap_0699 putative methyltransferase K00598 tam; trans-aconitate 2-methyltransferase [EC:2.1.1.144] D Hneap_1180 apolipoprotein N-acyltransferase K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269] D Hneap_1080 phospholipid/glycerol acyltransferase K22617 olsA; lyso-ornithine lipid O-acyltransferase [EC:2.3.1.270] D Hneap_1975 leucyl/phenylalanyl-tRNA/protein transferase K00684 aat; leucyl/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6] D Hneap_0726 transglutaminase domain protein K22452 tgpA; protein-glutamine gamma-glutamyltransferase [EC:2.3.2.13] D Hneap_0236 glycosyl transferase group 1 K00754 bshA; L-malate glycosyltransferase [EC:2.4.1.-] D Hneap_0902 prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145] D Hneap_1800 ApbE family lipoprotein K03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180] D Hneap_0511 ApbE family lipoprotein K03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180] D Hneap_0058 (Glutamate--ammonia-ligase) adenylyltransferase K00982 glnE; [glutamine synthetase] adenylyltransferase / [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase [EC:2.7.7.42 2.7.7.89] D Hneap_0175 diguanylate cyclase with GAF sensor K13069 E2.7.7.65; diguanylate cyclase [EC:2.7.7.65] D Hneap_0192 protein of unknown function UPF0061 K08997 SELENOO; protein adenylyltransferase [EC:2.7.7.108] D Hneap_0747 HPr kinase K06023 hprK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-] D Hneap_0532 tol-pal system-associated acyl-CoA thioesterase K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-] D Hneap_0168 phosphohistidine phosphatase, SixA K08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-] D Hneap_0604 hydrolase, TatD family K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D Hneap_1683 TatD-related deoxyribonuclease K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D Hneap_2093 nuclease (SNase domain protein) K01174 nuc; micrococcal nuclease [EC:3.1.31.1] D Hneap_2179 alpha/beta hydrolase fold protein K01175 ybfF; esterase [EC:3.1.-.-] D Hneap_2085 peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D Hneap_2031 peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D Hneap_2242 polysaccharide deacetylase K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104] D Hneap_1734 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase K11206 NIT1; deaminated glutathione amidase [EC:3.5.1.128] D Hneap_0841 amidohydrolase K18456 E3.5.4.32; 8-oxoguanine deaminase [EC:3.5.4.32] D Hneap_2387 endoribonuclease L-PSP K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10] D Hneap_1810 maf protein K25422 yceF; 7-methyl-GTP pyrophosphatase [EC:3.6.1.-] D Hneap_0889 ATPase associated with various cellular activities AAA_3 K03924 moxR; MoxR-like ATPase [EC:3.6.3.-] D Hneap_0184 ATPase associated with various cellular activities AAA_3 K03924 moxR; MoxR-like ATPase [EC:3.6.3.-] D Hneap_2019 carbohydrate kinase, YjeF related protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6] D Hneap_0956 conserved hypothetical protein K26055 scoD; (3R)-3-[(carboxylmethyl)amino]fatty acid synthase [EC:4.3.2.11] D Hneap_0301 UDP-N-acetylmuramate K02558 mpl; UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase [EC:6.3.2.45] D Hneap_1784 electron transport complex, RnfABCDGE type, D subunit K03614 rnfD; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit D [EC:7.1.1.11 7.2.1.2] D Hneap_1785 electron transport complex, RnfABCDGE type, C subunit K03615 rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] D Hneap_1786 electron transport complex, RnfABCDGE type, B subunit K03616 rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] D Hneap_1874 heavy metal translocating P-type ATPase K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9] C 99981 Carbohydrate metabolism C 99982 Energy metabolism D Hneap_1783 electron transport complex, RnfABCDGE type, G subunit K03612 rnfG; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit G D Hneap_1799 FMN-binding domain protein K03612 rnfG; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit G D Hneap_1782 electron transport complex, RnfABCDGE type, E subunit K03613 rnfE; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit E D Hneap_1787 electron transport complex, RnfABCDGE type, A subunit K03617 rnfA; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit A D Hneap_1092 von Willebrand factor type A K02448 norD; nitric oxide reductase NorD protein D Hneap_0910 von Willebrand factor type A K02448 norD; nitric oxide reductase NorD protein D Hneap_1588 von Willebrand factor type A K02448 norD; nitric oxide reductase NorD protein D Hneap_1094 CbbQ/NirQ/NorQ domain protein K04748 norQ; nitric oxide reductase NorQ protein D Hneap_0905 CbbQ/NirQ/NorQ domain protein K04748 norQ; nitric oxide reductase NorQ protein C 99983 Lipid metabolism C 99984 Nucleotide metabolism C 99985 Amino acid metabolism D Hneap_2227 protein of unknown function DUF540 K06203 cysZ; CysZ protein D Hneap_0253 Glyoxalase/bleomycin resistance protein/dioxygenase K08234 yaeR; glyoxylase I family protein D Hneap_1840 alanine racemase domain protein K06997 yggS; PLP dependent protein C 99986 Glycan metabolism C 99987 Cofactor metabolism D Hneap_2164 HemY domain protein K02498 hemY; HemY protein D Hneap_1186 2-polyprenylphenol 6-hydroxylase K03688 ubiB; ubiquinone biosynthesis protein D Hneap_1187 Sterol-binding domain protein K03690 ubiJ; ubiquinone biosynthesis accessory factor UbiJ D Hneap_2392 protein of unknown function DUF526 K09806 ubiK; ubiquinone biosynthesis accessory factor UbiK C 99988 Secondary metabolism C 99999 Others D Hneap_1862 CoA-binding domain protein K09181 yfiQ; acetyltransferase B B 09192 Unclassified: genetic information processing C 99973 Transcription D Hneap_2338 cold-shock DNA-binding domain protein K03704 cspA; cold shock protein D Hneap_2357 nitrogen regulatory protein P-II K04752 glnK; nitrogen regulatory protein P-II 2 C 99974 Translation C 99975 Protein processing D Hneap_0254 protein of unknown function DUF306 Meta and HslJ K03668 hslJ; heat shock protein HslJ D Hneap_1760 ATP-dependent Clp protease adaptor protein ClpS K06891 clpS; ATP-dependent Clp protease adaptor protein ClpS D Hneap_0385 trigger factor K03545 tig; trigger factor D Hneap_1530 SsrA-binding protein K03664 smpB; SsrA-binding protein D Hneap_2393 Mg chelatase, subunit ChlI K07391 comM; magnesium chelatase family protein D Hneap_2243 2OG-Fe(II) oxygenase K07394 K07394; SM-20-related protein D Hneap_1310 20S proteasome, A and B subunits K07395 K07395; putative proteasome-type protease D Hneap_2047 OsmC family protein K07397 yhfA; putative redox protein D Hneap_2169 ResB family protein K07399 resB; cytochrome c biogenesis protein D Hneap_0858 xanthine dehydrogenase accessory protein XdhC K07402 xdhC; xanthine dehydrogenase accessory factor C 99976 Replication and repair D Hneap_2155 DNA repair protein RadC K03630 radC; DNA repair protein RadC D Hneap_0053 protein of unknown function DUF195 K09760 rmuC; DNA recombination protein RmuC D Hneap_0675 protein of unknown function UPF0102 K07460 yraN; putative endonuclease D Hneap_2088 DNA protecting protein DprA K04096 smf; DNA processing protein D Hneap_1516 AAA ATPase central domain protein K07478 ycaJ; putative ATPase D Hneap_0939 Integrase catalytic region K07482 K07482; transposase, IS30 family D Hneap_0875 transposase IS3/IS911 family protein K07483 K07483; transposase D Hneap_2255 transposase IS3/IS911 family protein K07483 K07483; transposase D Hneap_2256 IS66 Orf2 family protein K07484 K07484; transposase D Hneap_0012 transposase IS116/IS110/IS902 family protein K07486 K07486; transposase D Hneap_0876 Integrase catalytic region K07497 K07497; putative transposase C 99979 Viral proteins C 99998 Others D Hneap_0770 conserved hypothetical protein K09747 ebfC; nucleoid-associated protein EbfC D Hneap_1411 cryptochrome, DASH family K25656 cry; cryptochrome B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D Hneap_1893 major facilitator superfamily MFS_1 K03292 TC.GPH; glycoside/pentoside/hexuronide:cation symporter, GPH family D Hneap_1676 amino acid permease-associated region K03294 TC.APA; basic amino acid/polyamine antiporter, APA family D Hneap_1019 acriflavin resistance protein K03296 TC.HAE1; hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 family C 99978 Cell growth D Hneap_1458 intracellular septation protein A K06190 ispZ; intracellular septation protein C 99993 Cell motility C 99995 Signaling proteins D Hneap_1697 signaling modulator of AmpD, AmpE K03807 ampE; AmpE protein D Hneap_2274 Fertility inhibition FinO-like protein K03607 proQ; ProP effector D Hneap_0383 GTP-binding protein TypA K06207 typA; GTP-binding protein D Hneap_1183 PhoH family protein K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins D Hneap_0641 PhoH family protein K07175 phoH2; PhoH-like ATPase C 99992 Structural proteins D Hneap_1518 outer membrane lipoprotein carrier protein LolA K03634 lolA; outer membrane lipoprotein carrier protein D Hneap_1166 outer membrane lipoprotein LolB K02494 lolB; outer membrane lipoprotein LolB D Hneap_0037 17 kDa surface antigen K06077 slyB; outer membrane lipoprotein SlyB D Hneap_1445 outer membrane chaperone Skp (OmpH) K06142 hlpA; outer membrane protein D Hneap_0060 outer membrane chaperone Skp (OmpH) K06142 hlpA; outer membrane protein D Hneap_0549 Peptidase M23 K06194 nlpD; lipoprotein NlpD D Hneap_1483 Capsule polysaccharide biosynthesis protein K07265 kpsS; capsular polysaccharide export protein D Hneap_1504 Capsule polysaccharide biosynthesis protein K07266 kpsC; capsular polysaccharide export protein D Hneap_1079 protein of unknown function DUF481 K07283 ydiY; putative salt-induced outer membrane protein D Hneap_1852 AsmA family protein K07289 asmA; AsmA protein D Hneap_0418 protein of unknown function DUF107 K07340 ybbJ; inner membrane protein D Hneap_0782 efflux transporter, RND family, MFP subunit K02005 ABC.CD.TX; HlyD family secretion protein D Hneap_2259 lipoprotein, osmotically inducible K04062 osmB; osmotically inducible lipoprotein OsmB D Hneap_0652 17 kDa surface antigen K04062 osmB; osmotically inducible lipoprotein OsmB D Hneap_2193 conserved hypothetical protein K15539 rodZ; cytoskeleton protein RodZ C 99994 Others D Hneap_0265 phosphate uptake regulator, PhoU K02039 phoU; phosphate transport system protein D Hneap_0579 periplasmic glucan biosynthesis protein MdoG K03670 mdoG; periplasmic glucans biosynthesis protein D Hneap_0582 periplasmic glucan biosynthesis protein MdoG K03670 mdoG; periplasmic glucans biosynthesis protein D Hneap_1279 ApaG domain protein K06195 apaG; ApaG protein D Hneap_0273 copper resistance B precursor K07233 pcoB; copper resistance protein B D Hneap_0928 NnrS family protein K07234 K07234; uncharacterized protein involved in response to NO B B 09194 Poorly characterized C 99996 General function prediction only D Hneap_1154 Colicin V production protein K03558 cvpA; membrane protein required for colicin V production D Hneap_2261 transport-associated K04065 osmY; hyperosmotically inducible periplasmic protein D Hneap_1425 globin K06886 glbN; hemoglobin D Hneap_2142 iron-sulfur cluster assembly accessory protein K15724 erpA; iron-sulfur cluster insertion protein D Hneap_1192 FeS assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB D Hneap_1194 FeS assembly protein SufD K09015 sufD; Fe-S cluster assembly protein SufD D Hneap_1514 ribonuclease BN K07058 K07058; membrane protein D Hneap_0670 FxsA cytoplasmic membrane protein K07113 fxsA; UPF0716 protein FxsA D Hneap_1199 Fe-S metabolism associated SufE K02426 sufE; cysteine desulfuration protein SufE D Hneap_1949 protein of unknown function DUF489 K07153 hflD; high frequency lysogenization protein D Hneap_2401 Cytochrome c oxidase caa3-type, assembly factor CtaG-related protein K02351 K02351; putative membrane protein D Hneap_0005 LemA family protein K03744 lemA; LemA protein D Hneap_2089 protein of unknown function DUF494 K03747 smg; Smg protein D Hneap_1155 Sporulation domain protein K03749 dedD; DedD protein D Hneap_2280 Sporulation domain protein K03112 damX; DamX protein D Hneap_1909 SNARE associated Golgi protein-related protein K03975 dedA; membrane-associated protein D Hneap_0884 protein of unknown function DUF202 K00389 yidH; putative membrane protein D Hneap_0274 Protein of unknown function DUF2078, membrane K08982 K08982; putative membrane protein D Hneap_1174 conserved hypothetical protein K08990 ycjF; putative membrane protein D Hneap_1705 SEC-C motif domain protein K09858 K09858; SEC-C motif domain protein D Hneap_0900 phosphate-starvation-inducible E K13256 psiE; protein PsiE D Hneap_1254 alkylphosphonate utilization operon protein PhnA K06193 phnA; protein PhnA C 99997 Function unknown D Hneap_0293 protein of unknown function DUF255 K06888 K06888; uncharacterized protein D Hneap_0217 protein of unknown function DUF255 K06888 K06888; uncharacterized protein D Hneap_1175 protein of unknown function DUF463 YcjX family protein K06918 K06918; uncharacterized protein D Hneap_1039 protein of unknown function DUF815 K06923 K06923; uncharacterized protein D Hneap_0378 protein of unknown function UPF0153 K06940 K06940; uncharacterized protein D Hneap_0398 protein of unknown function UPF0153 K06940 K06940; uncharacterized protein D Hneap_1890 amine oxidase K06954 K06954; uncharacterized protein D Hneap_1749 peptidase membrane zinc metallopeptidase putative K06973 K06973; uncharacterized protein D Hneap_0651 aminoglycoside phosphotransferase K07028 K07028; uncharacterized protein D Hneap_1556 protein of unknown function DUF81 K07090 K07090; uncharacterized protein D Hneap_0864 protein of unknown function DUF81 K07090 K07090; uncharacterized protein D Hneap_0218 protein of unknown function DUF839 K07093 K07093; uncharacterized protein D Hneap_0028 phosphodiesterase, MJ0936 family K07095 K07095; uncharacterized protein D Hneap_1086 phosphoesterase DHHA1 K07097 K07097; uncharacterized protein D Hneap_0556 protein of unknown function DUF395 YeeE/YedE K07112 K07112; uncharacterized protein D Hneap_0557 protein of unknown function DUF395 YeeE/YedE K07112 K07112; uncharacterized protein D Hneap_1366 protein of unknown function DUF395 YeeE/YedE K07112 K07112; uncharacterized protein D Hneap_1367 protein of unknown function DUF395 YeeE/YedE K07112 K07112; uncharacterized protein D Hneap_0676 LppC family lipoprotein K07121 K07121; uncharacterized protein D Hneap_0463 Sel1 domain protein repeat-containing protein K07126 K07126; uncharacterized protein D Hneap_0302 peptidase S16 lon domain protein K07157 K07157; uncharacterized protein D Hneap_2412 protein of unknown function DUF37 K08998 K08998; uncharacterized protein D Hneap_0805 Domain of unknown function DUF1791 K09004 K09004; uncharacterized protein D Hneap_0173 Domain of unknown function DUF1791 K09004 K09004; uncharacterized protein D Hneap_0180 Domain of unknown function DUF1791 K09004 K09004; uncharacterized protein D Hneap_0056 Domain of unknown function DUF1791 K09004 K09004; uncharacterized protein D Hneap_1146 Domain of unknown function DUF1791 K09004 K09004; uncharacterized protein D Hneap_2306 protein of unknown function DUF192 K09005 K09005; uncharacterized protein D Hneap_1932 Protein of unknown function K09117 K09117; uncharacterized protein D Hneap_0569 protein of unknown function DUF167 K09131 K09131; uncharacterized protein D Hneap_1265 protein of unknown function DUF493 K09158 K09158; uncharacterized protein D Hneap_1068 protein of unknown function UPF0153 K09160 K09160; uncharacterized protein D Hneap_1891 protein of unknown function DUF1365 K09701 K09701; uncharacterized protein D Hneap_0059 protein of unknown function DUF188 K09768 K09768; uncharacterized protein D Hneap_1459 YCII-related protein K09780 K09780; uncharacterized protein D Hneap_1726 protein of unknown function DUF343 K09791 K09791; uncharacterized protein D Hneap_0282 conserved hypothetical protein K09792 K09792; uncharacterized protein D Hneap_0584 conserved hypothetical protein K09794 K09794; uncharacterized protein D Hneap_1528 protein of unknown function UPF0125 K09801 K09801; uncharacterized protein D Hneap_0907 Protein of unknown function DUF2309 K09822 K09822; uncharacterized protein D Hneap_0211 Protein of unknown function DUF2309 K09822 K09822; uncharacterized protein D Hneap_0895 conserved hypothetical protein K09895 K09895; uncharacterized protein D Hneap_2277 conserved hypothetical protein K09902 K09902; uncharacterized protein D Hneap_2223 Protein of unknown function DUF2058 K09912 K09912; uncharacterized protein D Hneap_1321 conserved hypothetical protein K09921 K09921; uncharacterized protein D Hneap_0658 Protein of unknown function DUF2062 K09928 K09928; uncharacterized protein D Hneap_0292 Protein of unknown function DUF2063 K09929 K09929; uncharacterized protein D Hneap_0291 protein of unknown function DUF692 K09930 K09930; uncharacterized protein D Hneap_2009 Protein of unknown function DUF2065 K09937 K09937; uncharacterized protein D Hneap_2224 protein of unknown function DUF1415 K09941 K09941; uncharacterized protein D Hneap_0199 putative periplasmic ligand-binding sensor protein K09945 K09945; uncharacterized protein D Hneap_0505 protein of unknown function DUF1244 K09948 K09948; uncharacterized protein D Hneap_1606 protein of unknown function DUF1348 K09958 K09958; uncharacterized protein D Hneap_1408 Protein of unknown function DUF2237 K09966 K09966; uncharacterized protein D Hneap_0796 urea carboxylase-associated protein 2 K09967 K09967; uncharacterized protein D Hneap_0797 urea carboxylase-associated protein 1 K09967 K09967; uncharacterized protein D Hneap_2132 protein of unknown function DUF1022 K07276 K07276; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: May 10, 2024