+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Leptospira interrogans serovar Linhai</h2>
%<!-- w=600, -->
!
A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
C    LIL_12692 hypothetical protein	K15342 cas1; CRISP-associated protein Cas1 
C    LIL_13009 CRISPR-associated protein Cas1	K15342 cas1; CRISP-associated protein Cas1 
C    LIL_12693 CRISPR-associated protein Cas2	K09951 cas2; CRISPR-associated protein Cas2 
C    LIL_13010 hypothetical protein	K09951 cas2; CRISPR-associated protein Cas2 
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
D      LIL_12695 ATP-dependent RNA helicase	K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] 
D      LIL_13003 putative helicase	K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] 
C    Subtype I-A factors
D      LIL_12697 fruiting body developmental protein R	K19075 cst2; CRISPR-associated protein Cst2 
D      LIL_13008 RecB-like exonuclease	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
D      LIL_12698 fruiting body developmental protein S	K19089 cas5a_b_c; CRISPR-associated protein Cas5a/b/c 
C    Subtype I-B factors
D      LIL_13008 RecB-like exonuclease	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
C    Subtype I-C factors
D      LIL_13006 hypothetical protein	K19117 csd1; CRISPR-associated protein Csd1 
D      LIL_13007 hypothetical protein	K19118 csd2; CRISPR-associated protein Csd2 
D      LIL_13008 RecB-like exonuclease	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
D      LIL_13005 CRISPR-associated CT1134 family protein	K19119 cas5d; CRISPR-associated protein Cas5d 
C    Subtype I-D factors
D      LIL_13008 RecB-like exonuclease	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
D      LIL_13008 RecB-like exonuclease	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
#
A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
C    LIL_12704 hsdR; type I restriction enzyme	K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] 
C    LIL_12702 hsdS; type I restriction enzyme EcoprrI specificity protein	K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] 
C    LIL_12701 hsdM; type I restriction enzyme	K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] 
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      LIL_12827 methylase	K07317 K07317; adenine-specific DNA-methyltransferase [EC:2.1.1.72] 
D      LIL_12349 DNA methyltransferase	K24451 zim; modification methylase 
B  Type III R-M system
B  Type IV R-M system
C    LIL_10677 mrr; mrr restriction system protein	K07448 mrr; restriction system protein 
#
A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
D      LIL_30046 mazF; proteic killer gene system protein, growth inhibitor	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
D      LIL_40023 mazF; ppGpp-regulated growth inhibitor ChpA/MazF	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
D      LIL_30045 mazE; proteic killer gene system protein, suppressor of inhibitory function of MazF	K07172 mazE; antitoxin MazE 
D      LIL_40022 mazE1; transcriptional regulator/antitoxin MazE	K07172 mazE; antitoxin MazE 
D      LIL_11318 putative transcriptional regulator	K26986 mazE6; antitoxin MazE6 
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
D      LIL_40017 relB; DNA -damage-inducible protein J	K07473 dinJ; DNA-damage-inducible protein J 
C    YoeB-YefM
C    HipA-HipB
C    HicA-HicB
D      LIL_50010 XRE family transcriptional regulator	K18843 hicB; antitoxin HicB 
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
C    Doc-Phd
D      LIL_40055 doc; putative prophage maintenance system killer protein	K07341 doc; death on curing protein 
C    HigB-HigA
D      LIL_50009 vapI; Helix-turn-helix XRE-family like protein	K21498 higA-1; antitoxin HigA-1 
C    MqsR-MqsA
C    VapC-VapB
D      LIL_12749 vapC; PilT domain-containing protein	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-] 
D      LIL_12748 vagC; virulence-associated protein VagC	K18829 mvpT; antitoxin VapB 
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    Type II TA system related factors
D      LIL_13074 ftsZ; cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      LIL_11384 mreB; rod shape-determining protein MreB	K03569 mreB; rod shape-determining protein MreB and related proteins 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
B  Type V TA system
C    GhoT-GhoS
#
A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    LIL_11788 nifS; cysteine desulfhydrase	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
!
#<hr>
#[ <a href="/kegg/brite.html">BRITE</a> | <a href="/kegg/kegg2.html">KEGG2</a> | <a href="/kegg/">KEGG</a> ]<br>
#Last updated: November 7, 2023