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Mitochondrial Biogenesis - Leishmania mexicana
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AMitochondrial DNA transcription, translation, and replication factors
B Mitochondrial DNA-encoded proteins
C Mitochondrial respiratory chain complex I
C Mitochondrial respiratory chain complex III
C Cytochrome c oxidase
C F-type ATPase
B Mitochondrial transcription and translation factors
C Mitochondrial RNA polymerase
D LMXM_24_1150 mitochondrial DNA-directed RNA polymerase,putative K10908 POLRMT; DNA-directed RNA polymerase, mitochondrial [EC:2.7.7.6]
C Mitochondrial transcription factors
C Mitochondrial translation factors
D LMXM_22_1240 putative translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D LMXM_08_29_0720 hypothetical protein K02357 tsf; elongation factor Ts
D LMXM_18_0740 putative elongation factor Tu K02358 tuf; elongation factor Tu
D LMXM_28_1960 elongation factor G2-like protein K02355 fusA; elongation factor G
D LMXM_36_0570 putative Mitochondrial elongation factor G K02355 fusA; elongation factor G
C RNase MRP
C Mitochondrial ribonuclease P
D LMXM_32_1950 hypothetical protein K17655 MRPP3; mitochondrial ribonuclease P protein 3
D LMXM_34_5090 hypothetical protein K17655 MRPP3; mitochondrial ribonuclease P protein 3
C Other mitochondrial DNA transcription and translation factors
D LMXM_36_4810 hypothetical protein K17710 PTCD1; pentatricopeptide repeat domain-containing protein 1
D LMXM_36_1690 hypothetical protein K18156 ATP23; mitochondrial inner membrane protease ATP23 [EC:3.4.24.-]
D LMXM_33_2620 putative RNA helicase K17675 SUPV3L1; ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:5.6.2.6]
D LMXM_21_0670 metallo-beta-lactamase family-like protein K16639 LACTB2; endoribonuclease LACTB2 [EC:3.1.27.-]
D LMXM_19_0200 putative ADP,ATP carrier protein 1, mitochondrial precursor K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D LMXM_19_0210 ANC1; putative ADP,ATP carrier protein 1, mitochondrial precursor K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D LMXM_08_29_2780 mitochondrial carrier protein-like protein K15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28/37
D LMXM_25_0450 hypothetical protein K03595 era; GTPase
D LMXM_14_1370 putative tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D LMXM_13_1100 putative leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D LMXM_21_0895 putative aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D LMXM_36_3840 putative glycyl tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D LMXM_27_1310 putative arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D LMXM_34_5210 hypothetical protein K19828 MTG1; mitochondrial GTPase 1
D LMXM_09_0840 hypothetical protein K25877 MYG1; MYG1 exonuclease [EC:3.1.-.-]
B Mitochondrial DNA replication factors
C Mitochondrial DNA polymerase
D LMXM_32_0030 hypothetical protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Mitochondrial DNA maintenance factors
D LMXM_10_0610 putative endonuclease G K01173 ENDOG; endonuclease G, mitochondrial
D LMXM_21_1190 putative DNA repair and recombination protein,mitochondrial precursor K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D LMXM_11_0320 putative DNA repair and recombination protein,mitochondrial precursor K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D LMXM_11_0330 putative DNA repair and recombination protein,mitochondrial precursor K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D LMXM_28_2530 putative DNA repair and recombination protein,mitochondrial precursor K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D LMXM_07_1020 putative DNA repair and recombination protein,mitochondrial precursor K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
C Other Mitochondrial DNA replication factors
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AMitochondrial protein import machinery
B Endoplasmic reticulum membrane and cytosol
C ER-mitochondria encounter structure (ERMES) complex
C Other ER-memrane and cytosol factors
D LMXM_27_2400 putative heat shock protein DNAJ K09503 DNAJA2; DnaJ homolog subfamily A member 2
D LMXM_28_2770 putative heat-shock protein hsp70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D LMXM_28_2780 putative heat-shock protein hsp70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D LMXM_28_2820 putative heat shock protein 70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D LMXM_26_1240 heat shock protein 70-related protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
B Outer membrane
C Transporter outer membrane (TOM) complex
C TOB/SAM complex
C Porin
C ERMES complex
C Other outer membrane factor
B Inter membrane space
C Transporter inner membrane (TIM) 9/10 complex
D LMXM_22_0270 hypothetical protein K17778 TIM10; mitochondrial import inner membrane translocase subunit TIM10
C TIM8/13 complex
C Mitochondrial intermembrane space assembly (MIA) complex
D LMXM_15_0960 hypothetical protein K17783 ERV1; mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2]
B Inner mambrane
C MICOS complex
D LMXM_21_0735 hypothetical protein K17784 MICOS10; MICOS complex subunit MIC10
D LMXM_27_1530 hypothetical protein K17784 MICOS10; MICOS complex subunit MIC10
C MICOS complex (yeast)
D LMXM_21_0735 hypothetical protein K17784 MICOS10; MICOS complex subunit MIC10
D LMXM_27_1530 hypothetical protein K17784 MICOS10; MICOS complex subunit MIC10
C TIM22 complex
C TIM23 complex
D LMXM_09_1130 inner membrane preprotein translocase Tim17,putative K17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17
C Mitochondrial calcium uniporter complex
D LMXM_27_0780 hypothetical protein K20858 MCU; calcium uniporter protein, mitochondrial
D LMXM_07_0110 hypothetical protein K22827 MICU1; calcium uptake protein 1, mitochondrial
C Other inner membrane factors
D LMXM_08_29_0920 hypothetical protein K17800 LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial
D LMXM_34_1570 hypothetical protein K17803 OMS1; methyltransferase OMS1, mitochondrial [EC:2.1.1.-]
D LMXM_01_0335 hypothetical protein K22138 MPC1; mitochondrial pyruvate carrier 1
D LMXM_14_1460 hypothetical protein K22139 MPC2; mitochondrial pyruvate carrier 2
B Matrix
C MMC/PAM proteins
D LMXM_29_2460 putative heat shock 70-related protein 1, mitochondrial precursor K04043 dnaK; molecular chaperone DnaK
D LMXM_29_2470 putative heat shock 70-related protein 1, mitochondrial precursor K04043 dnaK; molecular chaperone DnaK
D LMXM_29_2550 putative heat shock 70-related protein 1, mitochondrial precursor K04043 dnaK; molecular chaperone DnaK
D LMXM_29_2490 putative heat shock 70-related protein 1, mitochondrial precursor K04043 dnaK; molecular chaperone DnaK
D LMXM_29_0730 putative co-chaperone GrpE K03687 GRPE; molecular chaperone GrpE
D LMXM_29_0735 heat shock protein grpe K03687 GRPE; molecular chaperone GrpE
D LMXM_24_1910 hypothetical protein K09539 DNAJC19; DnaJ homolog subfamily C member 19
C Other matrix factors
D LMXM_13_0870 metallo-peptidase, Clan ME, Family M16 K01412 PMPCA; mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]
D LMXM_32_2610 metallo-peptidase, Clan ME, Family M16 K01412 PMPCA; mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]
D LMXM_01_0650 metallo-peptidase, Clan ME, Family M16 K17732 PMPCB; mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]
D LMXM_34_1380 mitochondrial processing peptidase, beta subunit,putative,metallo-peptidase, Clan ME, Family M16 K17732 PMPCB; mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]
D LMXM_36_4450 metallo-peptidase, Clan MA(E), Family M3 K01410 MIPEP; mitochondrial intermediate peptidase [EC:3.4.24.59]
D LMXM_31_1850 chaperonin HSP60, mitochondrial precursor,putative K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D LMXM_36_2020 chaperonin HSP60, mitochondrial precursor K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D LMXM_36_2030 chaperonin HSP60, mitochondrial precursor K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D LMXM_26_0620 putative 10 kDa heat shock protein K04078 groES; chaperonin GroES
D LMXM_26_0640 putative 10 kDa heat shock protein K04078 groES; chaperonin GroES
D LMXM_34_2980 putative chaperone protein DNAj K03686 dnaJ; molecular chaperone DnaJ
D LMXM_04_0940 hypothetical protein K03686 dnaJ; molecular chaperone DnaJ
D LMXM_25_0800 hypothetical protein K17808 ZIM17; mitochondrial protein import protein ZIM17
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AMitochondrial quality control factors
B Regulator of mitochondrial biogenesis
C Ubiquitas transcription factors
D LMXM_28_1960 elongation factor G2-like protein K02355 fusA; elongation factor G
D LMXM_36_0570 putative Mitochondrial elongation factor G K02355 fusA; elongation factor G
C Nuclear respiratory factors
C Coactivators
C Proteins involved in Fe-S cluster biogenesis
D LMXM_27_1060 putative cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D LMXM_34_3620 putative iron-sulfur cluster assembly protein K22068 ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial
D LMXM_32_1355 hypothetical protein K22069 LYRM4; LYR motif-containing protein 4
D LMXM_25_1050 frataxin-like protein K19054 FXN; frataxin [EC:1.16.3.1]
D LMXM_30_2510 ferredoxin, 2fe-2s-like protein K22070 FDX1; ferredoxin-1, mitochondrial
D LMXM_30_2480 ferredoxin 2fe-2s-like protein K22071 FDX2; ferredoxin-2, mitochondrial
D LMXM_26_1050 hypothetical protein K22071 FDX2; ferredoxin-2, mitochondrial
D LMXM_30_2500 adrenodoxin-like protein K22071 FDX2; ferredoxin-2, mitochondrial
D LMXM_21_0420 ferredoxin NADP+ reductase-like protein K18914 FDXR; adrenodoxin-NADP+ reductase [EC:1.18.1.6]
D LMXM_29_2460 putative heat shock 70-related protein 1, mitochondrial precursor K04043 dnaK; molecular chaperone DnaK
D LMXM_29_2470 putative heat shock 70-related protein 1, mitochondrial precursor K04043 dnaK; molecular chaperone DnaK
D LMXM_29_2550 putative heat shock 70-related protein 1, mitochondrial precursor K04043 dnaK; molecular chaperone DnaK
D LMXM_29_2490 putative heat shock 70-related protein 1, mitochondrial precursor K04043 dnaK; molecular chaperone DnaK
D LMXM_01_0110 glutaredoxin-like protein K07390 grxD; monothiol glutaredoxin
D LMXM_16_0830 hypothetical protein K22063 ISCA1; iron-sulfur cluster assembly 1
D LMXM_34_1350 hypothetical protein K22072 ISCA2; iron-sulfur cluster assembly 2
D LMXM_24_1740 hypothetical protein K22073 IBA57; transferase CAF17, mitochondrial [EC:2.1.-.-]
D LMXM_26_0190 hypothetical protein K22074 NFU1; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
D LMXM_21_1855 hypothetical protein K22066 BOLA1; BolA-like protein 1
D LMXM_24_2040 hypothetical protein K22075 BOLA3; BolA-like protein 3
D LMXM_01_0570 putative tricarboxylate carrier K23503 SFXN5; sideroflexin-5
D LMXM_05_0680 sre-2/carboxylate carrier-like protein K23503 SFXN5; sideroflexin-5
C Other regulator of mitochondrial biogenesis
D LMXM_19_1540 choline/Carnitine o-acyltransferase-like protein K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
D LMXM_08_29_2020 putative protein kinase K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D LMXM_36_0900 putative protein kinase K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D LMXM_32_2360 hypothetical protein K18158 NCA2; nuclear control of ATPase protein 2
B Mitochondrial respiratory chain complex assembly factors
C Complex-I assembly factors
D LMXM_23_0890 hypothetical protein K18164 NDUFAF7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7
D LMXM_09_0367 hypothetical protein K24726 NDUFAF8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8
D LMXM_28_2470 MRP protein-like protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
C Complex-II assembly factors
C Complex-III assembly factors
D LMXM_33_1330 hypothetical protein K08900 BCS1; mitochondrial chaperone BCS1
C Complex-IV assembly factors
D LMXM_01_0290 hypothetical protein K18171 CMC1; COX assembly mitochondrial protein 1
D LMXM_23_1520 putative protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D LMXM_03_0100 putative cytochrome c oxidase assembly protein K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D LMXM_28_2680 cytochrome oxidase assembly protein-like protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D LMXM_03_0740 putative cytochrome c oxidase copper chaperone K02260 COX17; cytochrome c oxidase assembly protein subunit 17
D LMXM_19_1190 hypothetical protein K18183 COX19; cytochrome c oxidase assembly protein subunit 19
D LMXM_26_1970 putative electon transport protein SCO1/SCO2 K07152 SCO1; protein SCO1
D LMXM_04_1130 putative cytochrome c oxidase assembly factor K07152 SCO1; protein SCO1
C Complex-V assembly factors
B Mitochondrial dynamics
C Fission and Fusion factors
D LMXM_08_29_2200 putative GTP-binding protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C Actin cytoskeleton organization
D LMXM_25_0020 putative n-terminal acetyltransferase complex ard1 subunit homolog K17972 NAA20; N-terminal acetyltransferase B complex catalytic subunit [EC:2.3.1.254]
D LMXM_29_0520 hypothetical protein K17973 NAA25; N-terminal acetyltransferase B complex non-catalytic subunit
C Mitochondrial movement
D LMXM_16_1610 putative prohibitin K17080 PHB1; prohibitin 1
D LMXM_34_0070 putative prohibitin K17081 PHB2; prohibitin 2
C Retention of mitochondria
D LMXM_08_29_2200 putative GTP-binding protein K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C Morphogenesis factors
D LMXM_12_0040 hypothetical protein K17408 DAP3; small subunit ribosomal protein S29
B Mitophagy factors
C Autophagy-related proteins
D LMXM_32_0295 putative autophagocytosis protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
D LMXM_31_3890 cysteine peptidase, Clan CA, family C54,putative K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D LMXM_07_0010 putative ubiquitin activating E1 enzyme K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D LMXM_19_0820 putative ATG8/AUT7/APG8/PAZ2 K08341 GABARAP; GABA(A) receptor-associated protein
D LMXM_19_0830 putative ATG8/AUT7/APG8/PAZ2 K08341 GABARAP; GABA(A) receptor-associated protein
D LMXM_19_0840 putative ATG8/AUT7/APG8/PAZ2 K08341 GABARAP; GABA(A) receptor-associated protein
D LMXM_19_0850 putative ATG8/AUT7/APG8/PAZ2 K08341 GABARAP; GABA(A) receptor-associated protein
D LMXM_19_0860 putative ATG8/AUT7/APG8/PAZ2 K08341 GABARAP; GABA(A) receptor-associated protein
D LMXM_19_0880 putative ATG8/AUT7/APG8/PAZ2 K08341 GABARAP; GABA(A) receptor-associated protein
D LMXM_19_1630 putative ATG8/AUT7/APG8/PAZ2 K08341 GABARAP; GABA(A) receptor-associated protein
D LMXM_19_0870 putative ATG8/AUT7/APG8/PAZ2 K08341 GABARAP; GABA(A) receptor-associated protein
D LMXM_27_0390 hypothetical protein K17907 ATG9; autophagy-related protein 9
C Parkin-dependent mechanism factors
D LMXM_34_4540 hypothetical protein K19513 CLEC16A; protein CLEC16A
C Parkin-independent mechanism factors
D LMXM_32_0312 heat shock protein 83-1 K04079 HSP90A; molecular chaperone HtpG
D LMXM_32_0314 heat shock protein 83-1 K04079 HSP90A; molecular chaperone HtpG
D LMXM_32_0316 heat shock protein 83-1 K04079 HSP90A; molecular chaperone HtpG
C Other mitophagy factors
D LMXM_08_29_2020 putative protein kinase K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D LMXM_36_0900 putative protein kinase K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 14, 2024