+F Repair protein KO
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DNA Repair and Recombination Proteins - Lacticaseibacillus rhamnosus GG
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E LGG_00958 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LGG_01574 mpg; 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E LGG_00676 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LGG_01489 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E LGG_00328 srmB; ATP-dependent helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D LGG_02590 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LGG_02556 mutT; MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LGG_00118 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LGG_00207 Phosphohydrolase, MutT/nudix family K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LGG_02763 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LGG_02341 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E LGG_00958 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LGG_01574 mpg; 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E LGG_00676 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LGG_02215 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E LGG_00522 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E LGG_01760 mutM; Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E LGG_01489 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E LGG_00964 exoA; Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E LGG_01558 nfo; Endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E LGG_01598 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E LGG_01016 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E LGG_01761 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E LGG_02629 uvrA; Excinuclease ABC, subunit A K03701 uvrA; excinuclease ABC subunit A
E LGG_00924 uvrA; Excinuclease ABC, subunit A K03701 uvrA; excinuclease ABC subunit A
E LGG_00923 uvrB; Excinuclease ABC, subunit B K03702 uvrB; excinuclease ABC subunit B
E LGG_01358 uvrC; Excinuclease ABC subunit C, UvrABC system K03703 uvrC; excinuclease ABC subunit C
E LGG_01015 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LGG_01975 rep; DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LGG_00449 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LGG_01761 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E LGG_01016 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F LGG_02498 rpoB; DNA-directed RNA polymerase, beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F LGG_02497 rpoC; DNA-directed RNA polymerase, beta chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F LGG_02461 rpoA; DNA-directed RNA polymerase, subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F LGG_02551 DNA-directed RNA polymerase, delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
F LGG_01673 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F LGG_02521 mfd; Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E LGG_02235 mutS; DNA mismatch repair protein mutS K03555 mutS; DNA mismatch repair protein MutS
E LGG_00774 mutS; DNA mismatch repair protein mutS K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E LGG_02234 mutL; DNA mismatch repair protein mutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E LGG_01682 xseA; Exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E LGG_01681 xseB; Exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E LGG_01373 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E LGG_01617 polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E LGG_00002 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E LGG_01336 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E LGG_02260 holB; DNA polymerase III, delta subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E LGG_00963 dnaQ; DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E LGG_02266 dnaX; DNA polymerase III gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E LGG_01016 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E LGG_01015 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LGG_01975 rep; DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LGG_00449 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LGG_00010 ssb1; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E LGG_00012 ssb2; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E LGG_01107 ssb3; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E LGG_01541 ssb4; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E LGG_02082 ATP-dependent exoDNAse (Exonuclease V), alpha subunit-helicase superfamily I member K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E LGG_01308 recD; Helicase, RecD/TraA family protein K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E LGG_00889 recA; Protein recA K03553 recA; recombination protein RecA
E LGG_02643 recA; RecA recombinase K03553 recA; recombination protein RecA
E LGG_00752 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E LGG_00753 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E LGG_01671 priA; Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E LGG_00671 sbcC; DNA repair ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E LGG_00670 sbcD; Exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E LGG_00889 recA; Protein recA K03553 recA; recombination protein RecA
E LGG_02643 recA; RecA recombinase K03553 recA; recombination protein RecA
E LGG_02340 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E LGG_00004 recF; DNA replication and repair protein recF K03629 recF; DNA replication and repair protein RecF
E LGG_01660 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E LGG_01598 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E LGG_01549 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
E LGG_02264 recR; Recombination protein recR K06187 recR; recombination protein RecR
E LGG_01677 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E LGG_01486 recU; Holliday junction resolvase recU K03700 recU; recombination protein U
E LGG_00752 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E LGG_00753 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E LGG_01496 rexA; ATP-dependent nuclease, subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E LGG_01497 rexB; ATP-dependent nuclease, subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
E LGG_02203 cas1; CRISPR-associated protein, Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E LGG_00671 sbcC; DNA repair ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E LGG_00670 sbcD; Exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F LGG_00006 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F LGG_00005 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F LGG_01411 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F LGG_01391 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F LGG_01104 RecT family protein K07455 recT; recombination protein RecT
F LGG_01598 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F LGG_01549 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
F LGG_02264 recR; Recombination protein recR K06187 recR; recombination protein RecR
F LGG_01016 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F LGG_01386 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F LGG_01049 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F LGG_02629 uvrA; Excinuclease ABC, subunit A K03701 uvrA; excinuclease ABC subunit A
F LGG_00924 uvrA; Excinuclease ABC, subunit A K03701 uvrA; excinuclease ABC subunit A
F LGG_00923 uvrB; Excinuclease ABC, subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D LGG_00761 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D LGG_01010 umuC; ImpB/MucB/SamB family protein K03502 umuC; DNA polymerase V
C Other SOS response factors
D LGG_00889 recA; Protein recA K03553 recA; recombination protein RecA
D LGG_02643 recA; RecA recombinase K03553 recA; recombination protein RecA
D LGG_00717 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D LGG_01677 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D LGG_00010 ssb1; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D LGG_00012 ssb2; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D LGG_01107 ssb3; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D LGG_01541 ssb4; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D LGG_01831 recX; Regulatory protein recX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D LGG_01495 dinG; DNA polymerase III, Rad3-related DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D LGG_02590 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LGG_02556 mutT; MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LGG_00118 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LGG_00207 Phosphohydrolase, MutT/nudix family K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LGG_02763 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LGG_02341 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D LGG_01474 nrdE; Ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D LGG_01475 nrdF; Ribonucleoside-diphosphate reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D LGG_00763 ytqI; Phosphoesterase, DHH family protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
D LGG_02782 ytqI; Phosphoesterase, DHH family protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024