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Transfer RNA Biogenesis - Macaca mulatta (rhesus monkey)
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
D 705643 POP1; ribonucleases P/MRP protein subunit POP1 K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D 700209 POP4; LOW QUALITY PROTEIN: ribonuclease P protein subunit p29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D 697559 POP5; ribonuclease P/MRP protein subunit POP5 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D 696537 RPP30; ribonuclease P protein subunit p30 isoform X1 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D 713056 RPP21; ribonuclease P protein subunit p21 K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
D 706788 RPP14; ribonuclease P protein subunit p14 K14529 RPP14; ribonuclease P protein subunit RPP14 [EC:3.1.26.5]
D 712859 POP7; ribonuclease P protein subunit p20 K14527 RPP20; ribonuclease P/MRP protein subunit RPP20 [EC:3.1.26.5]
D 700829 RPP25L; ribonuclease P protein subunit p25-like protein K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 703796 RPP25; ribonuclease P protein subunit p25 K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 714421 ribonuclease P protein subunit p25-like protein K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 100429345 RPP38; ribonuclease P protein subunit p38 K14523 RPP38; ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5]
D 710505 RPP40; ribonuclease P protein subunit p40 isoform X1 K14530 RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D 106994515 ELAC1; zinc phosphodiesterase ELAC protein 1 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 718217 ELAC2; zinc phosphodiesterase ELAC protein 2 isoform X1 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 706533 RNASET2; ribonuclease T2 precursor K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
D 718712 pentatricopeptide repeat-containing protein 1, mitochondrial isoform X2 K17710 PTCD1; pentatricopeptide repeat domain-containing protein 1
C CCA adding factors
D 704550 TRNT1; CCA tRNA nucleotidyltransferase 1, mitochondrial K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
D 695083 TSEN2; tRNA-splicing endonuclease subunit Sen2 isoform X1 K15322 TSEN2; tRNA-splicing endonuclease subunit Sen2 [EC:4.6.1.16]
D 693919 TSEN34; tRNA-splicing endonuclease subunit Sen34 K15323 TSEN34; tRNA-splicing endonuclease subunit Sen34 [EC:4.6.1.16]
D 717481 TSEN15; tRNA-splicing endonuclease subunit Sen15 isoform X2 K15324 TSEN15; tRNA-splicing endonuclease subunit Sen15
D 702604 TSEN54; tRNA-splicing endonuclease subunit Sen54 K15326 TSEN54; tRNA-splicing endonuclease subunit Sen54
C tRNA splicing ligase complex
D 717258 RTCB; tRNA-splicing ligase RtcB homolog K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D 713165 C13H2orf49; ashwin K15432 ASW; ashwin
D 710094 RTRAF; UPF0568 protein C14orf166 homolog K15433 CGI99; RLL motif containing protein 1
D 106999137 FAM98B; protein FAM98B isoform X1 K15434 FAM98B; protein FAM98B
D 698327 DDX1; ATP-dependent RNA helicase DDX1 K13177 DDX1; ATP-dependent RNA helicase DDX1 [EC:5.6.2.7]
D 708590 ZBTB8OS; protein archease isoform X1 K24956 ZBTB8OS; protein archease
C Other tRNA splicing factors
D 717911 TRPT1; tRNA 2'-phosphotransferase 1 isoform X1 K10669 TRPT1; 2'-phosphotransferase [EC:2.7.1.160]
B tRNA transport factors
C tRNA export factors
D 709200 RAN; GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
D 717375 XPOT; exportin-T K14288 XPOT; exportin-T
D 718063 XPO1; exportin-1 K14290 XPO1; exportin-1
D 700664 XPO5; exportin-5 K14289 XPO5; exportin-5
D 696946 EEF1A2; elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
D 716010 EEF1A1; elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
D 100425937 elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
D 709017 putative elongation factor 1-alpha-like 3 K03231 EEF1A; elongation factor 1-alpha
D 694679 putative elongation factor 1-alpha-like 3 K03231 EEF1A; elongation factor 1-alpha
D 701651 GTPBP1; GTP-binding protein 1 K24887 GTPBP1; GTP-binding protein 1
C tRNA import factors
D 700852 TNPO3; transportin-3 K15436 TRPO3; transportin-3
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D 706899 EPRS; bifunctional glutamate/proline--tRNA ligase isoform X1 K14163 EPRS; bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]
D 700487 EARS2; probable glutamate--tRNA ligase, mitochondrial isoform X1 K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D 715499 PARS2; probable proline--tRNA ligase, mitochondrial isoform X3 K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D 711121 IARS2; isoleucine--tRNA ligase, mitochondrial K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 677705 IARS; isoleucine--tRNA ligase, cytoplasmic K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 714224 LARS2; probable leucine--tRNA ligase, mitochondrial K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 706792 LARS; leucine--tRNA ligase, cytoplasmic isoform X1 K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 714744 MARS; methionine--tRNA ligase, cytoplasmic K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 698275 MARS2; methionine--tRNA ligase, mitochondrial K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 708111 QARS; glutamine--tRNA ligase isoform X1 K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D 698998 RARS; arginine--tRNA ligase, cytoplasmic K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 699240 RARS2; probable arginine--tRNA ligase, mitochondrial isoform X1 K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 714516 KARS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D 707449 DARS; aspartate--tRNA ligase, cytoplasmic isoform X1 K22503 DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 707002 DARS2; aspartate--tRNA ligase, mitochondrial K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 695147 AIMP1; aminoacyl tRNA synthase complex-interacting multifunctional protein 1 K15437 AIMP1; aminoacyl tRNA synthase complex-interacting multifunctional protein 1
D 717612 AIMP2; aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform X1 K15438 AIMP2; aminoacyl tRNA synthase complex-interacting multifunctional protein 2
D 695426 EEF1E1; eukaryotic translation elongation factor 1 epsilon-1 K15439 EEF1E1; eukaryotic translation elongation factor 1 epsilon-1
C Other AARSs
D 702626 AARS2; alanine--tRNA ligase, mitochondrial isoform X1 K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 709492 AARS; alanine--tRNA ligase, cytoplasmic K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 700326 NARS2; probable asparagine--tRNA ligase, mitochondrial isoform X1 K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 695872 NARS; asparagine--tRNA ligase, cytoplasmic isoform X1 K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 697526 GARS; glycine--tRNA ligase isoform X1 K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D 707105 TARS2; threonine--tRNA ligase, mitochondrial isoform X1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 698423 TARSL2; threonine--tRNA ligase 2, cytoplasmic isoform X1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 701519 TARS; threonine--tRNA ligase, cytoplasmic isoform X2 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 695081 SARS2; serine--tRNA ligase, mitochondrial isoform X1 K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 697810 serine--tRNA ligase, cytoplasmic isoform X1 K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 695046 SARS; serine--tRNA ligase, cytoplasmic isoform X1 K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 694840 CARS2; probable cysteine--tRNA ligase, mitochondrial isoform X2 K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 706502 CARS; cysteine--tRNA ligase, cytoplasmic K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 715537 VARS; valine--tRNA ligase, mitochondrial isoform X1 K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 106997888 VARS2; valine--tRNA ligase, mitochondrial isoform X1 K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 698551 HARS; histidine--tRNA ligase, cytoplasmic K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 697009 HARS2; probable histidine--tRNA ligase, mitochondrial isoform X6 K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 710945 FARS2; phenylalanine--tRNA ligase, mitochondrial K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 716878 FARSA; phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 705557 FARSB; phenylalanine--tRNA ligase beta subunit isoform X1 K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D 697033 YARS2; tyrosine--tRNA ligase, mitochondrial K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 709003 YARS; tyrosine--tRNA ligase, cytoplasmic isoform X1 K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 706855 WARS; tryptophan--tRNA ligase, cytoplasmic isoform X2 K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 712332 WARS2; tryptophan--tRNA ligase, mitochondrial isoform X1 K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D 700895 DTD1; D-aminoacyl-tRNA deacylase 1 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 717267 DTD2; D-aminoacyl-tRNA deacylase 2 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 712203 alanyl-tRNA editing protein Aarsd1 isoform X1 K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
C AARS associated factors
D 720273 TRNAU1AP; tRNA selenocysteine 1-associated protein 1 isoform X1 K25102 TRNAU1AP; tRNA selenocysteine 1-associated protein 1
D 706083 HINT1; histidine triad nucleotide-binding protein 1 K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D 695521 HINT2; histidine triad nucleotide-binding protein 2, mitochondrial K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D 712779 HINT3; histidine triad nucleotide-binding protein 3 K12150 HINT3; adenosine 5'-monophosphoramidase HINT3 [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
D 712066 ADAT1; tRNA-specific adenosine deaminase 1 K15440 TAD1; tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
D 700860 ADAT2; tRNA-specific adenosine deaminase 2 isoform X1 K15441 TAD2; tRNA-specific adenosine deaminase 2 [EC:3.5.4.-]
D 106992295 ADAT3; probable inactive tRNA-specific adenosine deaminase-like protein 3 K15442 TAD3; tRNA-specific adenosine deaminase 3
C Dihydorouridine synthases
D 715662 DUS1L; tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like isoform X1 K05542 DUS1; tRNA-dihydrouridine synthase 1 [EC:1.3.1.88]
D 702051 DUS2; tRNA-dihydrouridine(20) synthase [NAD(P)+]-like isoform X1 K05543 DUS2; tRNA-dihydrouridine synthase 2 [EC:1.3.1.91]
D 719524 DUS3L; tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like isoform X1 K05544 DUS3; tRNA-dihydrouridine synthase 3 [EC:1.3.1.89]
D 699356 DUS4L; tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like K05545 DUS4; tRNA-dihydrouridine synthase 4 [EC:1.3.1.90]
C Methylthiotransferase
D 706409 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
C Methyltransferases
D 718227 TRMT1; tRNA (guanine(26)-N(2))-dimethyltransferase isoform X1 K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D 719425 TRMT2A; tRNA (uracil-5-)-methyltransferase homolog A K15332 TRMT2A; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.-]
D 702087 TRMT2B; tRNA (uracil(54)-C(5))-methyltransferase homolog isoform X1 K15331 TRMT2B; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D 712397 TARBP1; probable methyltransferase TARBP1 isoform X1 K15333 TRM3; tRNA guanosine-2'-O-methyltransferase [EC:2.1.1.34]
D 694987 NSUN2; tRNA (cytosine(34)-C(5))-methyltransferase K15335 NSUN2; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.203]
D 106996137 NSUN3; tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial isoform X2 K21969 NSUN3; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.-]
D 701490 NSUN6; putative methyltransferase NSUN6 isoform X1 K21971 NSUN6; methyltransferase NSUN6 [EC:2.1.1.-]
D 704146 TRMT5; tRNA (guanine(37)-N1)-methyltransferase K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D 695566 TRMT61A; tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D 703419 TRMT61B; tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial isoform X1 K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D 718229 TRMT6; tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 K03256 TRM6; tRNA (adenine58-N1)-methyltransferase non-catalytic subunit
D 710243 FTSJ1; putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase K14864 FTSJ1; tRNA (cytidine32/guanosine34-2'-O)-methyltransferase [EC:2.1.1.205]
D 715796 METTL1; tRNA (guanine-N(7)-)-methyltransferase isoform X1 K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D 717533 METTL2A; methyltransferase-like protein 2A K24974 METTL2; tRNA N(3)-methylcytidine methyltransferase METTL2 [EC:2.1.1.-]
D 694202 METTL6; methyltransferase-like protein 6 K00599 METTL6; tRNA N(3)-methylcytidine methyltransferase METTL6 [EC:2.1.1.-]
D 706917 ALKBH8; alkylated DNA repair protein alkB homolog 8 K10770 ALKBH8; alkylated DNA repair protein alkB homolog 8 [EC:1.14.11.- 2.1.1.229]
D 708751 TRMT10A; tRNA methyltransferase 10 homolog A K15445 TRMT10; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]
D 716301 TRMT10B; tRNA methyltransferase 10 homolog B K15445 TRMT10; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]
D 712712 TRMT11; tRNA (guanine(10)-N2)-methyltransferase homolog K15430 TRM11; tRNA (guanine10-N2)-methyltransferase [EC:2.1.1.214]
D 711396 TRMT13; tRNA:m(4)X modification enzyme TRM13 homolog K15446 TRM13; tRNA:m4X modification enzyme [EC:2.1.1.225]
D 722630 TRMT44; probable tRNA (uracil-O(2)-)-methyltransferase isoform X3 K15447 TRM44; tRNASer (uridine44-2'-O)-methyltransferase [EC:2.1.1.211]
D 714230 WDR4; tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 isoform X1 K15443 TRM82; tRNA (guanine-N(7)-)-methyltransferase subunit TRM82
D 717676 TRMT112; multifunctional methyltransferase subunit TRM112-like protein K15448 TRM112; multifunctional methyltransferase subunit TRM112
D 699758 TRDMT1; tRNA (cytosine(38)-C(5))-methyltransferase isoform X1 K15336 TRDMT1; tRNA (cytosine38-C5)-methyltransferase [EC:2.1.1.204]
D 715609 TRMO; tRNA (adenine(37)-N6)-methyltransferase K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D 703026 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase isoform X1 K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D 705848 TRMT12; tRNA wybutosine-synthesizing protein 2 homolog K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D 704515 TYW3; tRNA wybutosine-synthesizing protein 3 homolog K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
D 710047 LCMT2; tRNA wybutosine-synthesizing protein 4 K15451 PPM2; tRNA wybutosine-synthesizing protein 4 [EC:2.1.1.290 2.3.1.231]
D 699197 TYW5; tRNA wybutosine-synthesizing protein 5 K18066 TYW5; tRNA wybutosine-synthesizing protein 5 [EC:1.14.11.42]
D 711559 BCDIN3D; RNA 5'-monophosphate methyltransferase K25191 BCDIN3D; RNA 5'-monophosphate methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D 719360 PUS1; tRNA pseudouridine synthase A isoform X1 K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D 713746 PUS3; tRNA pseudouridine(38/39) synthase K01855 PUS3; tRNA pseudouridine38/39 synthase [EC:5.4.99.45]
D 699133 TRUB1; probable tRNA pseudouridine synthase 1 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D 700448 PUS7L; pseudouridylate synthase 7 homolog-like protein isoform X1 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 697463 PUS7; pseudouridylate synthase 7 homolog isoform X2 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 717862 PUS10; putative tRNA pseudouridine synthase Pus10 K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D 714162 RPUSD4; mitochondrial RNA pseudouridine synthase RPUSD4 K22538 RPUSD4; mitochondrial RNA pseudouridine synthase RPUSD4 [EC:5.4.99.-]
C Thiolation factors
D 714268 TRMU; mitochondrial tRNA-specific 2-thiouridylase 1 isoform X1 K21027 TRMU; tRNA-5-taurinomethyluridine 2-sulfurtransferase [EC:2.8.1.14]
D 719536 CTU1; cytoplasmic tRNA 2-thiolation protein 1 K14168 CTU1; cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-]
D 100424255 CTU2; cytoplasmic tRNA 2-thiolation protein 2 isoform X1 K14169 CTU2; cytoplasmic tRNA 2-thiolation protein 2
D 704077 NFS1; cysteine desulfurase, mitochondrial isoform X2 K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D 722618 URM1; ubiquitin-related modifier 1 K12161 URM1; ubiquitin related modifier 1
D 701166 MOCS3; adenylyltransferase and sulfurtransferase MOCS3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C KEOPS/EKC complex
D 716636 TP53RK; EKC/KEOPS complex subunit TP53RK K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D 709747 OSGEPL1; probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D 702512 OSGEP; probable tRNA N6-adenosine threonylcarbamoyltransferase K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D 707023 TPRKB; EKC/KEOPS complex subunit TPRKB isoform X1 K15901 TPRKB; EKC/KEOPS complex subunit TPRKB/CGI121
D 700924 LAGE3; EKC/KEOPS complex subunit LAGE3 K15902 LAGE3; EKC/KEOPS complex subunit LAGE3/PCC1
D 703985 EKC/KEOPS complex subunit LAGE3 isoform X1 K15902 LAGE3; EKC/KEOPS complex subunit LAGE3/PCC1
D 704509 GON7; EKC/KEOPS complex subunit GON7 K15903 GON7; EKC/KEOPS complex subunit GON7
C Elongator complex
D 713524 ELP1; elongator complex protein 1 K11373 ELP1; elongator complex protein 1
D 709483 ELP2; elongator complex protein 2 K11374 ELP2; elongator complex protein 2
D 713512 ELP3; elongator complex protein 3 K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D 695979 ELP4; elongator complex protein 4 isoform X1 K11375 ELP4; elongator complex protein 4
D 721799 ELP5; elongator complex protein 5 isoform X1 K11376 ELP5; elongator complex protein 5
D 711423 ELP6; elongator complex protein 6 K11377 ELP6; elongator complex protein 6
C Elongator related proteins
D 695309 DPH3; DPH3 homolog K15455 DPH3; diphthamide biosynthesis protein 3
D 106995386 DPH3 homolog K15455 DPH3; diphthamide biosynthesis protein 3
D 107000328 DPH3P1; putative DPH3 homolog B K15455 DPH3; diphthamide biosynthesis protein 3
D 693378 DPH3 homolog K15455 DPH3; diphthamide biosynthesis protein 3
D 712824 KTI12; protein KTI12 homolog K15456 KTI12; protein KTI12
C Other tRNA modification factors
D 100424180 YRDC; yrdC domain-containing protein, mitochondrial isoform X1 K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D 716422 TRIT1; tRNA dimethylallyltransferase isoform X1 K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D 719758 GTPBP3; tRNA modification GTPase GTPBP3, mitochondrial isoform X1 K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D 114673096 tRNA modification GTPase GTPBP3, mitochondrial K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D 717688 MTO1; protein MTO1 homolog, mitochondrial isoform X1 K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D 715940 QTRT1; queuine tRNA-ribosyltransferase catalytic subunit 1 isoform X1 K00777 QTRT1; queuine tRNA-ribosyltransferase catalytic subunit [EC:2.4.2.64]
D 710310 QTRT2; queuine tRNA-ribosyltransferase subunit QTRTD1 K15407 QTRT2; queuine tRNA-ribosyltransferase accessory subunit
D 696038 SEPHS1; selenide, water dikinase 1 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 710575 SEPHS2; selenide, water dikinase 2 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 696746 THUMPD1; THUMP domain-containing protein 1 K06963 TAN1; tRNA acetyltransferase TAN1
D 715853 THG1L; probable tRNA(His) guanylyltransferase K10761 THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79]
D 705248 ATE1; arginyl-tRNA--protein transferase 1 isoform X1 K00685 ATE1; arginyl-tRNA---protein transferase [EC:2.3.2.8]
D 708403 DALRD3; DALR anticodon-binding domain-containing protein 3 isoform X2 K24973 DALRD3; DALR anticodon-binding domain-containing protein 3
B tRNA degradation factors
C TRAMP complex
D 713853 TENT4A; non-canonical poly(A) RNA polymerase PAPD7 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
D 694589 TENT4B; terminal nucleotidyltransferase 4A isoform X4 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
D 716658 ZCCHC7; zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
D 706419 MTREX; exosome RNA helicase MTR4 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
C Rapid tRNA decay (RTD) pathway factors
D 714497 XRN1; 5'-3' exoribonuclease 1 isoform X2 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
D 700934 XRN2; 5'-3' exoribonuclease 2 isoform X1 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D 721277 BPNT1; 3'(2'),5'-bisphosphate nucleotidase 1 isoform X1 K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
D 715706 schlafen family member 13 isoform X1 K24459 SLFN13; schlafen family member 13 [EC:3.1.-.-]
D 695796 IFIT5; interferon-induced protein with tetratricopeptide repeats 5 K24850 IFIT5; interferon-induced protein with tetratricopeptide repeats 5
#
AProkaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D 106994515 ELAC1; zinc phosphodiesterase ELAC protein 1 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 718217 ELAC2; zinc phosphodiesterase ELAC protein 2 isoform X1 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 706533 RNASET2; ribonuclease T2 precursor K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D 704550 TRNT1; CCA tRNA nucleotidyltransferase 1, mitochondrial K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D 717258 RTCB; tRNA-splicing ligase RtcB homolog K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D 714224 LARS2; probable leucine--tRNA ligase, mitochondrial K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 706792 LARS; leucine--tRNA ligase, cytoplasmic isoform X1 K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 715499 PARS2; probable proline--tRNA ligase, mitochondrial isoform X3 K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D 697033 YARS2; tyrosine--tRNA ligase, mitochondrial K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 709003 YARS; tyrosine--tRNA ligase, cytoplasmic isoform X1 K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 706855 WARS; tryptophan--tRNA ligase, cytoplasmic isoform X2 K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 712332 WARS2; tryptophan--tRNA ligase, mitochondrial isoform X1 K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 707105 TARS2; threonine--tRNA ligase, mitochondrial isoform X1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 698423 TARSL2; threonine--tRNA ligase 2, cytoplasmic isoform X1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 701519 TARS; threonine--tRNA ligase, cytoplasmic isoform X2 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 711121 IARS2; isoleucine--tRNA ligase, mitochondrial K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 677705 IARS; isoleucine--tRNA ligase, cytoplasmic K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 714516 KARS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D 702626 AARS2; alanine--tRNA ligase, mitochondrial isoform X1 K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 709492 AARS; alanine--tRNA ligase, cytoplasmic K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 715537 VARS; valine--tRNA ligase, mitochondrial isoform X1 K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 106997888 VARS2; valine--tRNA ligase, mitochondrial isoform X1 K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 714744 MARS; methionine--tRNA ligase, cytoplasmic K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 698275 MARS2; methionine--tRNA ligase, mitochondrial K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 695081 SARS2; serine--tRNA ligase, mitochondrial isoform X1 K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 697810 serine--tRNA ligase, cytoplasmic isoform X1 K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 695046 SARS; serine--tRNA ligase, cytoplasmic isoform X1 K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 707002 DARS2; aspartate--tRNA ligase, mitochondrial K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 694840 CARS2; probable cysteine--tRNA ligase, mitochondrial isoform X2 K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 706502 CARS; cysteine--tRNA ligase, cytoplasmic K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 700487 EARS2; probable glutamate--tRNA ligase, mitochondrial isoform X1 K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D 708111 QARS; glutamine--tRNA ligase isoform X1 K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D 698998 RARS; arginine--tRNA ligase, cytoplasmic K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 699240 RARS2; probable arginine--tRNA ligase, mitochondrial isoform X1 K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 710945 FARS2; phenylalanine--tRNA ligase, mitochondrial K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 716878 FARSA; phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 705557 FARSB; phenylalanine--tRNA ligase beta subunit isoform X1 K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D 698551 HARS; histidine--tRNA ligase, cytoplasmic K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 697009 HARS2; probable histidine--tRNA ligase, mitochondrial isoform X6 K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 700326 NARS2; probable asparagine--tRNA ligase, mitochondrial isoform X1 K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 695872 NARS; asparagine--tRNA ligase, cytoplasmic isoform X1 K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
C Trans-editing factors
D 700895 DTD1; D-aminoacyl-tRNA deacylase 1 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 717267 DTD2; D-aminoacyl-tRNA deacylase 2 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 712203 alanyl-tRNA editing protein Aarsd1 isoform X1 K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferases
C Methyltransferases
D 715796 METTL1; tRNA (guanine-N(7)-)-methyltransferase isoform X1 K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D 719758 GTPBP3; tRNA modification GTPase GTPBP3, mitochondrial isoform X1 K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D 114673096 tRNA modification GTPase GTPBP3, mitochondrial K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D 715609 TRMO; tRNA (adenine(37)-N6)-methyltransferase K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D 719360 PUS1; tRNA pseudouridine synthase A isoform X1 K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D 699133 TRUB1; probable tRNA pseudouridine synthase 1 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D 700448 PUS7L; pseudouridylate synthase 7 homolog-like protein isoform X1 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 697463 PUS7; pseudouridylate synthase 7 homolog isoform X2 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D 704077 NFS1; cysteine desulfurase, mitochondrial isoform X2 K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
D 716636 TP53RK; EKC/KEOPS complex subunit TP53RK K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D 709747 OSGEPL1; probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D 702512 OSGEP; probable tRNA N6-adenosine threonylcarbamoyltransferase K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
C Other tRNA modification factors
D 717688 MTO1; protein MTO1 homolog, mitochondrial isoform X1 K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D 716422 TRIT1; tRNA dimethylallyltransferase isoform X1 K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D 711642 PTS; 6-pyruvoyl tetrahydrobiopterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D 696038 SEPHS1; selenide, water dikinase 1 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 710575 SEPHS2; selenide, water dikinase 2 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 100424180 YRDC; yrdC domain-containing protein, mitochondrial isoform X1 K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
B tRNA degradation factors
C 718973 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1 K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C 698376 ISG20; interferon-stimulated gene 20 kDa protein K12579 ISG20; interferon-stimulated gene 20 kDa protein [EC:3.1.13.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024