+E Ubiquitin system KO
#
Ubiquitin System - Monodelphis domestica (gray short-tailed opossum)
%
!
AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C 100021198 polyubiquitin-C K08770 UBC; ubiquitin C
C 100012532 UBA52; ubiquitin A-52 residue ribosomal protein fusion product 1 K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 100619355 ubiquitin K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 100032038 RPS27A; ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C 100617893 UBD; ubiquitin D K12157 UBD; ubiquitin D
C 103101483 NEDD8; neural precursor cell expressed, developmentally down-regulated 8 K12158 NEDD8; ubiquitin-like protein Nedd8
C 100017557 FAU; FAU, ubiquitin like and ribosomal protein S30 fusion K02983 RP-S30e; small subunit ribosomal protein S30e
C 100020081 ISG15; ISG15 ubiquitin-like modifier K12159 ISG15; ubiquitin cross-reactive protein
C 100023068 SUMO2; small ubiquitin-like modifier 2 K12160 SUMO; small ubiquitin-related modifier
C 100026374 small ubiquitin-related modifier 2-like K12160 SUMO; small ubiquitin-related modifier
C 107651218 SUMO3; small ubiquitin-like modifier 3 K12160 SUMO; small ubiquitin-related modifier
C 100019119 SUMO1; small ubiquitin-like modifier 1 K12160 SUMO; small ubiquitin-related modifier
C 100029139 GABARAPL2; GABA type A receptor associated protein like 2 K08341 GABARAP; GABA(A) receptor-associated protein
C 100016545 GABARAP; GABA type A receptor-associated protein K08341 GABARAP; GABA(A) receptor-associated protein
C 100010204 gamma-aminobutyric acid receptor-associated protein-like 1 K08341 GABARAP; GABA(A) receptor-associated protein
C 100019121 GABARAPL1; GABA type A receptor associated protein like 1 K08341 GABARAP; GABA(A) receptor-associated protein
C 100029238 ATG12; autophagy related 12 K08336 ATG12; ubiquitin-like protein ATG12
C 100011672 URM1; ubiquitin related modifier 1 K12161 URM1; ubiquitin related modifier 1
C 100618521 UFM1; ubiquitin fold modifier 1 K12162 UFM1; ubiquitin-fold modifier 1
C 100031866 ubiquitin-fold modifier 1 K12162 UFM1; ubiquitin-fold modifier 1
C 103093560 ubiquitin-fold modifier 1 K12162 UFM1; ubiquitin-fold modifier 1
C 100618075 ZFAND4; zinc finger AN1-type containing 4 K12163 ZFAND4; AN1-type zinc finger protein 4
#
AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C 100012835 UBA1; ubiquitin like modifier activating enzyme 1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C 100016572 SAE1; SUMO1 activating enzyme subunit 1 K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C 100011012 UBA2; ubiquitin like modifier activating enzyme 2 K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C 100011849 UBA3; ubiquitin like modifier activating enzyme 3 K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C 100019101 NAE1; NEDD8 activating enzyme E1 subunit 1 K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C 100022807 MOCS3; molybdenum cofactor synthesis 3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C 100030145 UBA5; ubiquitin like modifier activating enzyme 5 K12164 UBA5; ubiquitin-like modifier-activating enzyme 5
C 100028084 UBA7; ubiquitin like modifier activating enzyme 7 K10698 UBE1L; ubiquitin-activating enzyme E1-like [EC:6.2.1.45]
C 100012977 UBA6; ubiquitin like modifier activating enzyme 6 K10699 UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]
C 100024715 ATG7; autophagy related 7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
#
AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C 100011856 UBE2A; ubiquitin conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C 100014677 UBE2B; ubiquitin conjugating enzyme E2 B K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
C 100016483 UBE2C; ubiquitin conjugating enzyme E2 C K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C 100013744 UBE2D1; ubiquitin conjugating enzyme E2 D1 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 100014364 UBE2D3; ubiquitin conjugating enzyme E2 D3 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 100025703 UBE2D2; ubiquitin conjugating enzyme E2 D2 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 100025846 UBE2D4; ubiquitin conjugating enzyme E2 D4 (putative) K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 100019977 UBE2E3; ubiquitin conjugating enzyme E2 E3 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 100024546 UBE2E2; ubiquitin-conjugating enzyme E2 E2 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 100031458 UBE2E1; ubiquitin conjugating enzyme E2 E1 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 100014313 UBE2G1; ubiquitin conjugating enzyme E2 G1 K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C 100012869 UBE2G2; ubiquitin conjugating enzyme E2 G2 K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C 100020206 UBE2H; ubiquitin conjugating enzyme E2 H K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C 100025732 UBE2J1; ubiquitin conjugating enzyme E2 J1 K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
C 100017913 UBE2J2; ubiquitin conjugating enzyme E2 J2 K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C 100021920 UBE2K; ubiquitin conjugating enzyme E2 K K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C 100027828 UBE2L3; ubiquitin conjugating enzyme E2 L3 K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 100025425 UBE2L6; ubiquitin conjugating enzyme E2 L6 K04553 UBE2L6; ubiquitin/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]
C 100011853 UBE2N; ubiquitin conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 100011673 ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 100619214 UBE2O; ubiquitin conjugating enzyme E2 O K10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
C 100020755 UBE2Q1; ubiquitin conjugating enzyme E2 Q1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 100017992 UBE2QL1; ubiquitin conjugating enzyme E2 Q family like 1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 100012311 UBE2Q2; ubiquitin conjugating enzyme E2 Q2 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 100016923 CDC34; cell division cycle 34 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 100011407 UBE2R2; ubiquitin conjugating enzyme E2 R2 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 100032761 UBE2S; ubiquitin conjugating enzyme E2 S K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C 100014786 UBE2T; ubiquitin conjugating enzyme E2 T K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
C 103096205 UBE2U; ubiquitin conjugating enzyme E2 U (putative) K10584 UBE2U; ubiquitin-conjugating enzyme E2 U [EC:2.3.2.23]
C 100028124 UBE2W; ubiquitin conjugating enzyme E2 W K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C 100021140 UBE2Z; ubiquitin conjugating enzyme E2 Z K10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]
C 100027051 BIRC6; baculoviral IAP repeat containing 6 K10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
B UBL-conjugating enzymes
C 100009846 UBE2I; ubiquitin conjugating enzyme E2 I K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C 100023491 UBE2F; ubiquitin conjugating enzyme E2 F (putative) K10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]
C 100025425 UBE2L6; ubiquitin conjugating enzyme E2 L6 K04553 UBE2L6; ubiquitin/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]
C 100010740 ATG3; autophagy related 3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C 100015423 ATG10; autophagy related 10 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
C 100032739 UFC1; ubiquitin-fold modifier conjugating enzyme 1 K12165 UFC1; ufm1-conjugating enzyme 1
#
AUbiquitin ligases (E3)
B HECT type E3
C 100013023 UBE3A; ubiquitin protein ligase E3A K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
C 100028483 UBE3B; ubiquitin protein ligase E3B K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
C 100016776 UBE3C; ubiquitin protein ligase E3C K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C 100024270 UBE3D; ubiquitin protein ligase E3D K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C 100015651 SMURF1; SMAD specific E3 ubiquitin protein ligase 1 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 100029596 SMURF2; SMAD specific E3 ubiquitin protein ligase 2 K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 100032356 ITCH; itchy E3 ubiquitin protein ligase K05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
C 100029107 WWP1; WW domain containing E3 ubiquitin protein ligase 1 K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
C 100020484 WWP2; WW domain containing E3 ubiquitin protein ligase 2 K05630 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]
C 100014089 TRIP12; thyroid hormone receptor interactor 12 K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C 100020178 NEDD4; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C 100022149 NEDD4L; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase K13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]
C 100010537 HUWE1; HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C 100018773 AREL1; apoptosis resistant E3 ubiquitin protein ligase 1 K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
C 100030880 UBR5; ubiquitin protein ligase E3 component n-recognin 5 K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
C 100014320 G2E3; G2/M-phase specific E3 ubiquitin protein ligase K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C 100017074 HERC1; HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 K10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]
C 100012223 HERC2; E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
C 100015909 HERC3; HECT and RLD domain containing E3 ubiquitin protein ligase 3 K10614 HERC3; E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]
C 100010813 HERC4; HECT and RLD domain containing E3 ubiquitin protein ligase 4 K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]
C 100021107 HACE1; HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 K12166 HACE1; E3 ubiquitin-protein ligase HACE1 [EC:2.3.2.26]
C 100030905 HECW1; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 K12167 HECW1; E3 ubiquitin-protein ligase HECW1 [EC:2.3.2.26]
C 100022096 HECW2; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]
C 100012904 HECTD1; HECT domain E3 ubiquitin protein ligase 1 K12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]
C 100024451 HECTD2; HECT domain E3 ubiquitin protein ligase 2 K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]
C 100024899 HECTD3; HECT domain E3 ubiquitin protein ligase 3 K12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]
C 100618157 HECTD4; HECT domain E3 ubiquitin protein ligase 4 K17849 HECTD4; E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26]
C HECT type E3 associated proteins
D 100027985 NDFIP1; Nedd4 family interacting protein 1 K25839 NDFIP; NEDD4 family-interacting protein
D 100013618 NDFIP2; Nedd4 family interacting protein 2 K25839 NDFIP; NEDD4 family-interacting protein
D 100031983 N4BP3; NEDD4 binding protein 3 K26473 N4BP3; NEDD4-binding protein 3
B U-box type E3
C 100025132 UBE4A; ubiquitination factor E4A K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
C 100024477 UBE4B; ubiquitination factor E4B K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C 100016998 STUB1; STIP1 homology and U-box containing protein 1 K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 100016525 PPIL2; peptidylprolyl isomerase like 2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C 100027038 PRPF19; pre-mRNA processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
C 100013429 RBBP6; RB binding protein 6, ubiquitin ligase K10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]
C 100026714 UBOX5; U-box domain containing 5 K10600 UBOX5; U-box domain-containing protein 5
B Single Ring-finger type E3
C BRE1 proteins
D 100017440 RNF20; ring finger protein 20 K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
D 100013089 RNF40; ring finger protein 40 K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
D 100031184 CBL; Cbl proto-oncogene K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
D 100011932 CBLB; Cbl proto-oncogene B K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
D 100023698 CBLC; Cbl proto-oncogene C K22518 CBLC; E3 ubiquitin-protein ligase CBL-C [EC:2.3.2.27]
C SINA (Seven in absentia) proteins
D 100016498 SIAH1; siah E3 ubiquitin protein ligase 1 K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D 100011762 SIAH2; siah E3 ubiquitin protein ligase 2 K08742 SIAH2; E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]
C Ligand of Numb proteins
D 100017959 LNX1; ligand of numb-protein X 1 K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 100019761 LNX2; ligand of numb-protein X 2 K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 100012495 PDZRN3; PDZ domain containing ring finger 3 K15682 PDZRN3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
C March proteins
D 100015910 MARCH1; membrane associated ring-CH-type finger 1 K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 100027542 MARCH8; membrane associated ring-CH-type finger 8 K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 100017551 MARCH2; membrane associated ring-CH-type finger 2 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 100012164 MARCH4; membrane associated ring-CH-type finger 4 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 100015452 MARCH9; membrane associated ring-CH-type finger 9 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 100021012 MARCH11; membrane associated ring-CH-type finger 11 K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
D 100024142 MARCH5; membrane associated ring-CH-type finger 5 K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D 100019081 MARCH6; membrane associated ring-CH-type finger 6 K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
D 100015408 MARCH7; membrane associated ring-CH-type finger 7 K10662 MARCH7; E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27]
D 100025564 MARCH10; membrane associated ring-CH-type finger 10 K10665 MARCH10; E3 ubiquitin-protein ligase MARCH10 [EC:2.3.2.27]
C MDM2/MDM4 proteins
D 100021398 MDM2; MDM2 proto-oncogene K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
D 103092862 E3 ubiquitin-protein ligase Mdm2-like K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
D 100017700 MDM4; MDM4, p53 regulator K10127 MDM4; protein Mdm4
C NFX1 proteins
D 100009971 NFX1; nuclear transcription factor, X-box binding 1 K12236 NFX1; transcriptional repressor NF-X1
D 100019444 NFXL1; nuclear transcription factor, X-box binding like 1 K15683 NFXL1; NF-X1-type zinc finger protein NFXL1
C Pellino proteins
D 100031864 PELI1; pellino E3 ubiquitin protein ligase 1 K11964 PELI; pellino [EC:2.3.2.27]
D 100015598 PELI3; pellino E3 ubiquitin protein ligase family member 3 K11964 PELI; pellino [EC:2.3.2.27]
D 100025906 PELI2; pellino E3 ubiquitin protein ligase family member 2 K11964 PELI; pellino [EC:2.3.2.27]
C Peripheral membrane proteins
D 100018530 PEX10; peroxisomal biogenesis factor 10 K13346 PEX10; peroxin-10
D 100021388 PEX12; peroxisomal biogenesis factor 12 K13345 PEX12; peroxin-12
D 100027546 PEX2; peroxisomal biogenesis factor 2 K06664 PEX2; peroxin-2
C RBR proteins
D 100032502 PARK2; parkin RBR E3 ubiquitin protein ligase K04556 PARK2; parkin [EC:2.3.2.31]
D 100028173 ANKIB1; ankyrin repeat and IBR domain containing 1 K11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 [EC:2.3.2.31]
D 100016251 ARIH1; ariadne RBR E3 ubiquitin protein ligase 1 K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D 100020639 ARIH2; ariadne RBR E3 ubiquitin protein ligase 2 K11969 ARIH2; ariadne-2 [EC:2.3.2.31]
D 100011102 RBCK1; RANBP2-type and C3HC4-type zinc finger containing 1 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 100023095 RNF14; ring finger protein 14 K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
D 100030572 RNF19A; ring finger protein 19A, RBR E3 ubiquitin protein ligase K11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]
D 100032415 RNF19B; ring finger protein 19B K11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.31]
D 100030741 RNF31; ring finger protein 31 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
D 100021251 RNF34; ring finger protein 34 K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 100018074 RFFL; ring finger and FYVE like domain containing E3 ubiquitin protein ligase K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 100025103 RNF144B; ring finger protein 144B K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 100028271 RNF144A; ring finger protein 144A K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 100022084 RNF168; ring finger protein 168 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
D 100012888 RNF169; ring finger protein 169 K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
D 100010996 RNF183; ring finger protein 183 K22157 RNF183; E3 ubiquitin-protein ligase RNF183 [EC:2.3.2.31]
D 100015550 RNF216; ring finger protein 216 K11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]
D 100030618 RNF217; ring finger protein 217 K11977 RNF217; E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.31]
C TRAF proteins
D 100017243 TRAF2; TNF receptor associated factor 2 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
D 100022268 TRAF5; TNF receptor associated factor 5 K09849 TRAF5; TNF receptor-associated factor 5
D 100010055 TRAF6; TNF receptor associated factor 6 K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
D 100011568 TRAF7; TNF receptor associated factor 7 K10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]
C TRIM/RBCC proteins
D 100013924 MID2; midline 2 K10647 TRIM1; midline 2 [EC:2.3.2.27]
D 100024711 TRIM2; tripartite motif containing 2 K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 100023100 TRIM3; tripartite motif containing 3 K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 100018451 TRIM4; tripartite motif containing 4 K12000 TRIM7; tripartite motif-containing protein 7
D 103096724 tripartite motif-containing protein 7-like K12000 TRIM7; tripartite motif-containing protein 7
D 100029031 TRIM8; tripartite motif containing 8 K12001 TRIM8; tripartite motif-containing protein 8 [EC:2.3.2.27]
D 100010191 TRIM9; tripartite motif containing 9 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 100022507 TRIM67; tripartite motif containing 67 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 100023798 TRIM10; tripartite motif containing 10 K12002 TRIM10; tripartite motif-containing protein 10
D 100011616 TRIM11; E3 ubiquitin-protein ligase TRIM11 K10650 TRIM11; tripartite motif-containing protein 11 [EC:2.3.2.27]
D 100022167 TRIM13; tripartite motif containing 13 K12003 TRIM13; tripartite motif-containing protein 13 [EC:2.3.2.27]
D 100010477 TRIM14; tripartite motif containing 14 K12004 TRIM14; tripartite motif-containing protein 14
D 100023842 TRIM15; tripartite motif containing 15 K12005 TRIM15; tripartite motif-containing protein 15
D 100022148 TRIM16; tripartite motif containing 16 K12006 TRIM16; tripartite motif-containing protein 16
D 100018227 MID1; midline 1 K08285 TRIM18; midline 1 [EC:2.3.2.27]
D 100018910 TRIM23; tripartite motif containing 23 K07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]
D 100022776 TRIM24; tripartite motif containing 24 K08881 TRIM24; tripartite motif-containing protein 24 [EC:2.3.2.27]
D 100013883 TRIM25; tripartite motif containing 25 K10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]
D 100022140 TRIM26; tripartite motif containing 26 K12008 TRIM26; tripartite motif-containing protein 26
D 103102863 uncharacterized LOC103102863 K12008 TRIM26; tripartite motif-containing protein 26
D 100030959 TRIM29; tripartite motif containing 29 K12010 TRIM29; tripartite motif-containing protein 29
D 100012777 TRIM32; tripartite motif containing 32 K10607 TRIM32; tripartite motif-containing protein 32 [EC:2.3.2.27]
D 100033175 TRIM33; tripartite motif containing 33 K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
D 100030596 TRIM35; tripartite motif containing 35 K12012 TRIM35; tripartite motif-containing protein 35
D 100016228 TRIM36; tripartite motif containing 36 K12013 TRIM36; tripartite motif-containing protein 36 [EC:2.3.2.27]
D 100010737 TRIM37; tripartite motif containing 37 K10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]
D 100022234 TRIM39; E3 ubiquitin-protein ligase TRIM39 K12015 TRIM39; tripartite motif-containing protein 39 [EC:2.3.2.27]
D 100023777 TRIM40; tripartite motif containing 40 K12016 TRIM40; tripartite motif-containing protein 40
D 100019471 TRIM41; tripartite motif containing 41 K12017 TRIM41; tripartite motif-containing protein 41 [EC:2.3.2.27]
D 100025054 TRIM42; tripartite motif containing 42 K12018 TRIM42; tripartite motif-containing protein 42
D 103094032 tripartite motif-containing protein 43-like K12019 TRIM43S; tripartite motif-containing protein 43/48/49/64/77
D 103092820 probable E3 ubiquitin-protein ligase TRIML1 K12019 TRIM43S; tripartite motif-containing protein 43/48/49/64/77
D 100010124 TRIM44; tripartite motif containing 44 K12020 TRIM44; tripartite motif-containing protein 44
D 100011500 TRIM45; tripartite motif containing 45 K12021 TRIM45; tripartite motif-containing protein 45
D 100021963 TRIM46; tripartite motif containing 46 K12022 TRIM46; tripartite motif-containing protein 46
D 100022533 TRIM47; tripartite motif containing 47 K12023 TRIM47; tripartite motif-containing protein 47
D 100027651 E3 ubiquitin/ISG15 ligase TRIM25-like K12023 TRIM47; tripartite motif-containing protein 47
D 103101680 TRIM50; tripartite motif containing 50 K12024 TRIM50_73_74; tripartite motif-containing protein 50/73/74
D 100031069 TRIM54; tripartite motif containing 54 K10653 TRIM54; tripartite motif-containing protein 54
D 100029317 TRIM55; tripartite motif containing 55 K10654 TRIM55; tripartite motif-containing protein 55
D 100024449 tripartite motif-containing protein 54-like K10654 TRIM55; tripartite motif-containing protein 55
D 100010918 TRIM58; tripartite motif containing 58 K12027 TRIM58; tripartite motif-containing protein 58 [EC:2.3.2.27]
D 100016436 tripartite motif-containing protein 59-like K12028 TRIM59; tripartite motif-containing protein 59
D 100016634 tripartite motif-containing protein 59-like K12028 TRIM59; tripartite motif-containing protein 59
D 100028174 tripartite motif-containing protein 59-like K12028 TRIM59; tripartite motif-containing protein 59
D 103102885 tripartite motif-containing protein 59-like K12028 TRIM59; tripartite motif-containing protein 59
D 100016282 tripartite motif-containing protein 59-like K12028 TRIM59; tripartite motif-containing protein 59
D 100026944 TRIM62; tripartite motif containing 62 K12030 TRIM62; tripartite motif-containing protein 62 [EC:2.3.2.27]
D 100015426 TRIM63; E3 ubiquitin-protein ligase TRIM63 K10655 TRIM63; tripartite motif-containing protein 63 [EC:2.3.2.27]
D 100027149 TRIM65; tripartite motif containing 65 K12031 TRIM65; tripartite motif-containing protein 65
D 100029424 TRIM66; tripartite motif containing 66 K12032 TRIM66; tripartite motif-containing protein 66
D 100012500 TRIM69; tripartite motif containing 69 K12034 TRIM69; tripartite motif-containing protein 69 [EC:2.3.2.27]
D 100032082 TRIM71; tripartite motif containing 71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D 100012696 TRIM72; tripartite motif containing 72 K12036 TRIM72; tripartite motif-containing protein 72
C UBR box proteins
D 100010751 UBR1; ubiquitin protein ligase E3 component n-recognin 1 K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D 100009912 UBR2; ubiquitin protein ligase E3 component n-recognin 2 K10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]
D 100024537 UBR3; ubiquitin protein ligase E3 component n-recognin 3 (putative) K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
D 100027779 UBR4; ubiquitin protein ligase E3 component n-recognin 4 K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
D 100014488 UBR7; ubiquitin protein ligase E3 component n-recognin 7 (putative) K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D 100015225 AMFR; autocrine motility factor receptor K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 100025870 AIRE; autoimmune regulator K10603 AIRE; autoimmune regulator
D 100024627 BFAR; bifunctional apoptosis regulator K15684 BFAR; bifunctional apoptosis regulator
D 100010782 BIRC2; baculoviral IAP repeat-containing protein 2 K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 100010741 baculoviral IAP repeat-containing protein 2-like K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 100016651 XIAP; X-linked inhibitor of apoptosis K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
D 100025295 BIRC7; baculoviral IAP repeat containing 7 K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
D 100014817 BRAP; BRCA1 associated protein K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D 554178 BRCA1; BRCA1, DNA repair associated K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D 100010322 CBLL1; Cbl proto-oncogene like 1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D 103093274 E3 ubiquitin-protein ligase Hakai-like K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D 100022704 CCNB1IP1; cyclin B1 interacting protein 1 K10639 CCNB1IP1; E3 ubiquitin-protein ligase CCNP1IP1 [EC:2.3.2.27]
D 100027841 CHFR; checkpoint with forkhead and ring finger domains K10644 CHFR; E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27]
D 100016711 CNOT4; CCR4-NOT transcription complex subunit 4 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D 100021538 DCST1; DC-STAMP domain containing 1 K22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]
D 100027452 DTX4; deltex E3 ubiquitin ligase 4 K06058 DTX; deltex [EC:2.3.2.27]
D 100029021 DTX2; deltex E3 ubiquitin ligase 2 K06058 DTX; deltex [EC:2.3.2.27]
D 103094279 E3 ubiquitin-protein ligase DTX1-like K06058 DTX; deltex [EC:2.3.2.27]
D 103096551 DTX3L; deltex E3 ubiquitin ligase 3L K06058 DTX; deltex [EC:2.3.2.27]
D 100010382 DZIP3; DAZ interacting zinc finger protein 3 K10642 DZIP3; E3 ubiquitin-protein ligase DZIP3 [EC:2.3.2.27]
D 100033325 FANCL; Fanconi anemia complementation group L K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D 100030409 KCMF1; potassium channel modulatory factor 1 K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D 100011228 LRSAM1; leucine rich repeat and sterile alpha motif containing 1 K10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]
D 100021202 LTN1; listerin E3 ubiquitin protein ligase 1 K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D 100032065 MAP3K1; mitogen-activated protein kinase kinase kinase 1 K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
D 100017301 MEX3D; mex-3 RNA binding family member D K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 100010051 MEX3C; mex-3 RNA binding family member C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 100010853 MEX3B; mex-3 RNA binding family member B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 100022815 MEX3A; mex-3 RNA binding family member A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 100019390 MGRN1; mahogunin ring finger 1 K10604 MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]
D 100011183 MIB1; mindbomb E3 ubiquitin protein ligase 1 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 100012507 MIB2; mindbomb E3 ubiquitin protein ligase 2 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 100017943 MKRN1; makorin ring finger protein 1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 100025193 MKRN2; makorin ring finger protein 2 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 103099349 probable E3 ubiquitin-protein ligase makorin-3 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 100619821 E3 ubiquitin-protein ligase makorin-1-like K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 100023555 MUL1; mitochondrial E3 ubiquitin protein ligase 1 K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D 100013024 MYCBP2; MYC binding protein 2, E3 ubiquitin protein ligase K10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]
D 100018640 MYLIP; myosin regulatory light chain interacting protein K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 100031255 NEURL1B; neuralized E3 ubiquitin protein ligase 1B K01931 NEUR; protein neuralized [EC:2.3.2.27]
D 100028512 NEURL1; neuralized E3 ubiquitin protein ligase 1 K01931 NEUR; protein neuralized [EC:2.3.2.27]
D 100033184 NEURL3; neuralized E3 ubiquitin protein ligase 3 K15689 NEURL3; E3 ubiquitin-protein ligase NEURL3 [EC:2.3.2.27]
D 100025259 NHLRC1; NHL repeat containing E3 ubiquitin protein ligase 1 K10602 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:2.3.2.27]
D 100011311 RNF219; ring finger protein 219 K24091 OBI1; ORC ubiquitin ligase 1 [EC:2.3.2.27]
D 100011037 PJA2; praja ring finger ubiquitin ligase 2 K10634 PJA2; E3 ubiquitin-protein ligase Praja2 [EC:2.3.2.27]
D 100023569 RAD18; RAD18, E3 ubiquitin protein ligase K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 100011241 RAG1; recombination activating 1 K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
D 100024151 RCHY1; ring finger and CHY zinc finger domain containing 1 K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D 100015136 RC3H2; ring finger and CCCH-type domains 2 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 100016049 RC3H1; ring finger and CCCH-type domains 1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 100021432 RFWD2; ring finger and WD repeat domain 2 K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
D 100023964 RFWD3; ring finger and WD repeat domain 3 K15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]
D 100618862 RING1; ring finger protein 1 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 100018875 RNF2; ring finger protein 2 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 100021810 RNF4; ring finger protein 4 K22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
D 100024090 RNF5; ring finger protein 5 K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 100028582 RNF185; ring finger protein 185 K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 100019425 RNF6; ring finger protein 6 K22753 RNF6; E3 ubiquitin-protein ligase RNF6 [EC:2.3.2.27]
D 100619045 RNF8; ring finger protein 8 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
D 100018455 RNF10; ring finger protein 10 K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D 100011301 RNF11; ring finger protein 11 K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D 100010121 RING finger protein 11-like K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D 100009881 RLIM; ring finger protein, LIM domain interacting K16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]
D 100012118 RNF13; ring finger protein 13 K15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
D 100011066 RNF25; ring finger protein 25 K10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]
D 100024486 RNF26; ring finger protein 26 K15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]
D 100017572 RNF38; ring finger protein 38 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 100031738 RNF44; ring finger protein 44 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 103103111 RNF41; ring finger protein 41 K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 100011054 RNF43; ring finger protein 43 K15694 RNF43; E3 ubiquitin-protein ligase RNF43 [EC:2.3.2.27]
D 100018069 RNF103; ring finger protein 103 K15695 RNF103; E3 ubiquitin-protein ligase RNF103 [EC:2.3.2.27]
D 100019758 RNF111; ring finger protein 111 K10635 RNF111; E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27]
D 100016395 RING finger protein 112-like K25173 RNF112; E3 ubiquitin-protein ligase RNF112 [EC:2.3.2.27]
D 100016431 RING finger protein 112-like K25173 RNF112; E3 ubiquitin-protein ligase RNF112 [EC:2.3.2.27]
D 103106037 RING finger protein 112-like K25173 RNF112; E3 ubiquitin-protein ligase RNF112 [EC:2.3.2.27]
D 100029030 RNF114; ring finger protein 114 K15697 RNF114; E3 ubiquitin-protein ligase RNF114 [EC:2.3.2.27]
D 100012646 RNF115; ring finger protein 115 K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 100016676 RNF126; ring finger protein 126 K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 100016112 RNF121; ring finger protein 121 K15698 RNF121_175; RING finger protein 121/175
D 100032887 RNF122; ring finger protein 122 K15699 RNF122; RING finger protein 122
D 100028024 RNF123; ring finger protein 123 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 100023988 RNF125; ring finger protein 125 K12170 RNF125; E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]
D 100028589 RNF128; ring finger protein 128, E3 ubiquitin protein ligase K10629 RNF128; E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27]
D 100032093 RNF130; ring finger protein 130 K15701 RNF130; E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27]
D 100013307 RNF133; ring finger protein 133 K15702 RNF133; E3 ubiquitin-protein ligase RNF133 [EC:2.3.2.27]
D 100031064 RNF138; ring finger protein 138 K10668 RNF138; E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27]
D 100026171 RNF139; ring finger protein 139 K15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]
D 100030244 RNF145; ring finger protein 145 K23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]
D 100024288 RNF146; ring finger protein 146 K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
D 100015936 RNF149; ring finger protein 149 K15704 RNF149; E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27]
D 100016328 RNF152; ring finger protein 152 K15705 RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]
D 100022233 RNF157; ring finger protein 157 K25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]
D 100017991 RNF165; ring finger protein 165 K17821 RNF165; E3 ubiquitin-protein ligase RNF165 [EC:2.3.2.27]
D 100026153 RNF166; ring finger protein 166 K17044 RNF166; E3 ubiquitin-protein ligase RNF166 [EC:2.3.2.27]
D 100017491 RNF167; ring finger protein 167 K15706 RNF167; E3 ubiquitin-protein ligase RNF167 [EC:2.3.2.27]
D 100033046 RNF170; ring finger protein 170 K15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]
D 100032362 RNF180; ring finger protein 180 K15708 RNF180; E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27]
D 100029991 RNF181; ring finger protein 181 K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D 100030007 E3 ubiquitin-protein ligase RNF181-like K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D 100026160 RNF182; ring finger protein 182 K11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]
D 103092899 E3 ubiquitin-protein ligase RNF182-like K11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]
D 100027549 RNF186; ring finger protein 186 K25214 RNF186; E3 ubiquitin-protein ligase RNF186 [EC:2.3.2.27]
D 100030710 RNF213; ring finger protein 213 K22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]
D 100014163 RNF220; ring finger protein 220 K25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
D 100010510 RNFT1; ring finger protein, transmembrane 1 K22379 RNFT1; E3 ubiquitin-protein ligase RNFT1 [EC:2.3.2.27]
D 100029842 SART1; squamous cell carcinoma antigen recognized by T-cells 1 K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D 100026682 SHPRH; SNF2 histone linker PHD RING helicase K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D 100015104 SH3RF1; SH3 domain containing ring finger 1 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 100028475 SH3RF2; SH3 domain containing ring finger 2 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 100020602 SH3RF3; SH3 domain containing ring finger 3 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 100617443 HLTF; helicase like transcription factor K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 100017483 SYVN1; synoviolin 1 K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D 100024251 TMEM129; transmembrane protein 129 K22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]
D 100024201 TOPORS; TOP1 binding arginine/serine rich protein K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
D 103093464 E3 ubiquitin-protein ligase Topors-like K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
D 100028100 TRAIP; TRAF interacting protein K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D 100618256 TTC3; tetratricopeptide repeat domain 3 K15712 TTC3; E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27]
D 100018911 UHRF1; ubiquitin like with PHD and ring finger domains 1 K10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D 100015318 UHRF2; ubiquitin like with PHD and ring finger domains 2 K15713 UHRF2; E3 ubiquitin-protein ligase UHRF2 [EC:2.3.2.27]
D 100010478 UNKL; unkempt family like zinc finger K23047 UNKL; E3 ubiquitin-protein ligase UNKL [EC:2.3.2.27]
D 100012340 ZNF598; zinc finger protein 598 K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D 100027155 ZFP91; ZFP91 zinc finger protein K25175 ZFP91; E3 ubiquitin-protein ligase ZFP91 [EC:2.3.2.27]
D 100032540 ZNRF2; zinc and ring finger 2 K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
D 100010811 ZNRF1; zinc and ring finger 1 K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
D 100030631 ZNRF3; zinc and ring finger 3 K16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]
D 100024804 ZNRF4; zinc and ring finger 4 K15715 ZNRF4; E3 ubiquitin-protein ligase ZNRF4 [EC:2.3.2.27]
D 100028146 ZSWIM2; zinc finger SWIM-type containing 2 K15716 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 [EC:2.3.2.27]
B Atypical E3
C 100017291 JADE2; jade family PHD finger 2 K22155 JADE2; E3 ubiquitin-protein ligase Jade-2 [EC:2.3.2.27]
C 100619646 E4F1; E4F transcription factor 1 K22401 E4F1; transcription factor E4F1 / E3 ubiquitin-protein ligase [EC:2.3.2.27]
C 100016241 NSMCE1; NSE1 homolog, SMC5-SMC6 complex component K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
C 100010765 IRF2BP1; interferon regulatory factor 2 binding protein 1 K22383 IRF2BP; interferon regulatory factor 2-binding protein
C 100022460 IRF2BPL; interferon regulatory factor 2 binding protein like K22383 IRF2BP; interferon regulatory factor 2-binding protein
B UBL E3 ligases
C 100013521 RBX1; ring-box 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 100024201 TOPORS; TOP1 binding arginine/serine rich protein K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
C 103093464 E3 ubiquitin-protein ligase Topors-like K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
C 100020173 RANBP2; RAN binding protein 2 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C 100025757 PIAS1; protein inhibitor of activated STAT 1 K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C 100018269 PIAS2; protein inhibitor of activated STAT 2 K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]
C 100029233 E3 SUMO-protein ligase PIAS2-like K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]
C 100012780 PIAS3; protein inhibitor of activated STAT 3 K16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]
C 100022245 PIAS4; protein inhibitor of activated STAT 4 K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
C 100029464 PML; promyelocytic leukemia K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
C 100030846 CBX4; chromobox 4 K11452 CBX4; E3 SUMO-protein ligase CBX4 [EC:2.3.2.-]
C 100032252 NSMCE2; NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C 103097907 RNF212; ring finger protein 212 K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 103104414 RNF212B; ring finger protein 212B K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C 100010056 ZBED1; zinc finger BED-type containing 1 K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 100018787 ZNF451; zinc finger protein 451 K25176 ZNF451; E3 SUMO-protein ligase ZNF451 [EC:2.3.2.-]
C 100024844 HERC6; HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 K22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]
C 100020314 UFL1; UFM1 specific ligase 1 K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
C 100015896 DCUN1D1; defective in cullin neddylation 1 domain containing 1 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 100022007 DCUN1D2; defective in cullin neddylation 1 domain containing 2 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 100026409 DCUN1D3; defective in cullin neddylation 1 domain containing 3 K17823 DCUN1D3; DCN1-like protein 3
C 100011186 DCUN1D5; defective in cullin neddylation 1 domain containing 5 K17824 DCUN1D4_5; DCN1-like protein 4/5
C 100018695 DCUN1D4; defective in cullin neddylation 1 domain containing 4 K17824 DCUN1D4_5; DCN1-like protein 4/5
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E 100013521 RBX1; ring-box 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 100013348 CUL1; cullin 1 K03347 CUL1; cullin 1
D Adaptor protein
E 100014810 SKP1; S-phase kinase associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E 100029508 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 100031160 FBXW11; F-box and WD repeat domain containing 11 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 100013249 FBXW2; F-box and WD repeat domain containing 2 K10261 FBXW2; F-box and WD-40 domain protein 2
E 100029445 FBXW4; F-box and WD repeat domain containing 4 K10262 FBXW4; F-box and WD-40 domain protein 4
E 100022310 FBXW5; F-box and WD repeat domain containing 5 K10263 FBXW5; F-box and WD-40 domain protein 5
E 100617365 FBXW7; F-box and WD repeat domain containing 7 K10260 FBXW7; F-box and WD-40 domain protein 7
E 100023212 FBXW8; F-box and WD repeat domain containing 8 K10264 FBXW8; F-box and WD-40 domain protein 8
E 100010249 FBXW9; F-box and WD repeat domain containing 9 K10265 FBXW9; F-box and WD-40 domain protein 9
E 103098932 CDRT1; CMT1A duplicated region transcript 1 K10266 FBXW10; F-box and WD-40 domain protein 10
E 100620019 FBXW12; F-box and WD repeat domain containing 12 K10267 FBXW12S; F-box and WD-40 domain protein 12/13/14/15/16/17/19
E 100020421 SKP2; S-phase kinase associated protein 2 K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
E 100017701 FBXL20; F-box and leucine rich repeat protein 20 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 100010986 FBXL3; F-box and leucine rich repeat protein 3 K10269 FBXL3; F-box and leucine-rich repeat protein 3
E 100027180 FBXL4; F-box and leucine rich repeat protein 4 K10270 FBXL4; F-box and leucine-rich repeat protein 4
E 100012405 FBXL5; F-box and leucine rich repeat protein 5 K10271 FBXL5; F-box and leucine-rich repeat protein 5
E 100018579 FBXL6; F-box and leucine rich repeat protein 6 K10272 FBXL6; F-box and leucine-rich repeat protein 6
E 100020930 FBXL7; F-box and leucine rich repeat protein 7 K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 100015351 FBXL8; F-box and leucine rich repeat protein 8 K10274 FBXL8; F-box and leucine-rich repeat protein 8
E 100020092 LRRC29; leucine rich repeat containing 29 K10275 FBXL9; F-box and leucine-rich repeat protein 9
E 100015947 KDM2B; lysine demethylase 2B K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 100029240 KDM2A; lysine demethylase 2A K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 103104734 lysine-specific demethylase 2B-like K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 100013889 FBXL12; F-box and leucine rich repeat protein 12 K10278 FBXL12; F-box and leucine-rich repeat protein 12
E 100017719 FBXL13; F-box and leucine rich repeat protein 13 K10279 FBXL13; dynein regulatory complex subunit 6
E 100017399 FBXL14; F-box and leucine rich repeat protein 14 K10280 FBXL14; F-box and leucine-rich repeat protein 14
E 100023008 FBXL15; F-box and leucine rich repeat protein 15 K10281 FBXL15; F-box and leucine-rich repeat protein 15
E 100020965 FBXL16; F-box and leucine rich repeat protein 16 K10282 FBXL16; F-box and leucine-rich repeat protein 16
E 100031220 FBXL17; F-box and leucine rich repeat protein 17 K10283 FBXL17; F-box and leucine-rich repeat protein 17
E 100015019 FBXL18; F-box and leucine rich repeat protein 18 K10284 FBXL18; F-box and leucine-rich repeat protein 18
E 100619516 FBXL19; F-box and leucine rich repeat protein 19 K10285 FBXL19; F-box and leucine-rich repeat protein 19
E 100023205 FBXL22; F-box and leucine rich repeat protein 22 K10288 FBXL22; F-box and leucine-rich repeat protein 22
E 100013582 CCNF; cyclin F K10289 CCNF; F-box protein 1 (cyclin F)
E 100018509 FBXO2; F-box protein 2 K10099 FBXO2; F-box protein 2
E 100031407 FBXO3; F-box protein 3 K10290 FBXO3; F-box protein 3
E 100018021 FBXO4; F-box protein 4 K10291 FBXO4; F-box protein 4
E 100032184 FBXO5; F-box protein 5 K10292 FBXO5; F-box protein 5
E 100018391 F-box only protein 6-like K10100 FBXO6; F-box protein 6
E 100018430 F-box only protein 6-like K10100 FBXO6; F-box protein 6
E 100016137 FBXO7; F-box protein 7 K10293 FBXO7; F-box protein 7
E 100014085 FBXO8; F-box protein 8 K10294 FBXO8; F-box protein 8
E 100017217 FBXO9; F-box protein 9 K10295 FBXO9; F-box protein 9
E 100018625 FBXO10; F-box protein 10 K10296 FBXO10; F-box protein 10
E 100033355 FBXO11; F-box protein 11 K10297 FBXO11; F-box protein 11
E 100021362 FBXO15; F-box protein 15 K10298 FBXO15; F-box protein 15
E 100033177 FBXO16; F-box protein 16 K10299 FBXO16; F-box protein 16
E 100022916 FBXO18; F-box protein, helicase, 18 K10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]
E 100012301 LMO7; LIM domain 7 K06084 LMO7; F-box protein 20
E 100023362 FBXO21; F-box protein 21 K10301 FBXO21; F-box protein 21
E 100025686 FBXO22; F-box protein 22 K10302 FBXO22; F-box protein 22
E 100027578 TSPAN17; tetraspanin 17 K10303 FBXO23; F-box protein 23
E 100018506 FBXO24; F-box protein 24 K10304 FBXO24; F-box protein 24
E 100028604 FBXO25; F-box protein 25 K10305 FBXO25_32; F-box protein 25/32
E 100026040 FBXO32; F-box protein 32 K10305 FBXO25_32; F-box protein 25/32
E 100013812 FBXO27; F-box protein 27 K10102 FBXO27; F-box protein 27
E 103102959 F-box only protein 27-like K10102 FBXO27; F-box protein 27
E 100018738 FBXO28; F-box protein 28 K10306 FBXO28; F-box protein 28
E 100026657 FBXO30; F-box protein 30 K10307 FBXO30; F-box protein 30
E 100018330 FBXO31; F-box protein 31 K10308 FBXO31; F-box protein 31
E 100029327 FBXO33; F-box protein 33 K10310 FBXO33; F-box protein 33
E 103096049 FBXO34; F-box protein 34 K10311 FBXO34; F-box protein 34
E 100020855 FBXO36; F-box protein 36 K10312 FBXO36; F-box protein 36
E 103102115 F-box only protein 36-like K10312 FBXO36; F-box protein 36
E 100027068 FBXO38; F-box protein 38 K10313 FBXO38; F-box protein 38
E 100018090 FBXO40; F-box protein 40 K10315 FBXO40; F-box protein 40
E 100023172 FBXO41; F-box protein 41 K10316 FBXO41; F-box protein 41
E 103101010 FBXO42; F-box protein 42 K10317 FBXO42; F-box protein 42
E 100030521 FBXO43; F-box protein 43 K10318 FBXO43; F-box protein 43
E 100018470 FBXO44; F-box only protein 44 K10103 FBXO44; F-box protein 44
E 100022177 FBXO45; F-box protein 45 K10319 FBXO45; F-box protein 45
E 100617783 FBXO46; F-box protein 46 K10320 FBXO46; F-box protein 46
E 100018083 FBXO47; F-box protein 47 K10321 FBXO47; F-box protein 47
E 100031737 FBXO48; F-box protein 48 K27313 FBXO48; F-box protein 48
C Cul2 complex
D Ring finger protein
E 100013521 RBX1; ring-box 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 100018154 CUL2; cullin 2 K03870 CUL2; cullin 2
D Adoptor protein
E 100028060 ELOC; elongin C K03872 ELOC; elongin-C
E 100018279 ELOB; elongin B K03873 ELOB; elongin-B
D Target recognizing subunit
E 100024305 VHL; von Hippel-Lindau tumor suppressor K03871 VHL; von Hippel-Lindau disease tumor supressor
E 100028925 LRR1; leucine rich repeat protein 1 K10348 LRR1; LRR-repeat protein 1
E 100013380 FEM1C; fem-1 homolog C K25805 FEM1A_C; protein fem-1 homolog A/C
E 100018807 FEM1A; fem-1 homolog A K25805 FEM1A_C; protein fem-1 homolog A/C
E 100018974 FEM1B; fem-1 homolog B K10349 FEM1B; protein fem-1 homolog B
E 100009934 APPBP2; amyloid beta precursor protein binding protein 2 K25806 APPBP2; amyloid protein-binding protein 2
E 100029028 KLHDC2; kelch domain containing 2 K25807 KLHDC2; kelch domain-containing protein 2
E 100616901 KLHDC3; kelch domain-containing protein 3 K25808 KLHDC3; kelch domain-containing protein 3
E 100015528 KLHDC10; kelch domain containing 10 K25809 KLHDC10; kelch domain-containing protein 10
E 100012020 ZER1; zyg-11 related cell cycle regulator K10350 ZYG11; Zyg-11 protein
E 100018195 ZYG11B; protein zyg-11 homolog B K10350 ZYG11; Zyg-11 protein
E 100018018 ZYG11A; zyg-11 family member A, cell cycle regulator K10350 ZYG11; Zyg-11 protein
E 100011359 ZSWIM8; zinc finger SWIM-type containing 8 K25207 ZSWIM8; zinc finger SWIM domain-containing protein 8
C Cul3 complex
D Ring finger protein
E 100013521 RBX1; ring-box 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 100015239 CUL3; cullin 3 K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E 100010015 KLHL1; kelch like family member 1 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 100021130 KLHL4; kelch-like protein 4 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 100022250 KLHL5; kelch like family member 5 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 100013485 KLHL3; kelch like family member 3 K10443 KLHL2_3; kelch-like protein 2/3
E 100021973 KLHL2; kelch like family member 2 K10443 KLHL2_3; kelch-like protein 2/3
E 100027523 KLHL6; kelch like family member 6 K10444 KLHL6; kelch-like protein 6
E 100011154 KLHL7; kelch like family member 7 K10445 KLHL7; kelch-like protein 7
E 100017063 KLHL8; kelch like family member 8 K10446 KLHL8; kelch-like protein 8
E 100015280 KLHL13; kelch like family member 13 K10447 KLHL9_13; kelch-like protein 9/13
E 100027105 kelch-like protein 9 K10447 KLHL9_13; kelch-like protein 9/13
E 103092729 kelch-like protein 9 K10447 KLHL9_13; kelch-like protein 9/13
E 100027066 kelch-like protein 9 K10447 KLHL9_13; kelch-like protein 9/13
E 100012063 KLHL10; kelch like family member 10 K10448 KLHL10; kelch-like protein 10
E 100012803 KLHL11; kelch like family member 11 K10449 KLHL11; kelch-like protein 11
E 100015286 KLHL12; kelch like family member 12 K10450 KLHL12; kelch-like protein 12
E 100031036 KLHL14; kelch like family member 14 K10451 KLHL14; kelch-like protein 14
E 100010406 KLHL15; kelch like family member 15 K10452 KLHL15; kelch-like protein 15
E 100027517 GAN; gigaxonin K10453 KLHL16; kelch-like protein 16 (gigaxonin)
E 100027387 KLHL17; kelch like family member 17 K10454 KLHL17; kelch-like protein 17 (actinfilin)
E 100018682 KLHL18; kelch like family member 18 K10455 KLHL18; kelch-like protein 18
E 100012710 KEAP1; kelch like ECH associated protein 1 K10456 KLHL19; kelch-like protein 19
E 100020927 KLHL20; kelch like family member 20 K10457 KLHL20; kelch-like protein 20
E 103094277 kelch-like protein 20 K10457 KLHL20; kelch-like protein 20
E 100032685 KLHL21; kelch like family member 21 K10458 KLHL21; kelch-like protein 21
E 100016255 KLHL22; kelch like family member 22 K10459 KLHL22; kelch-like protein 22
E 100017617 KLHL23; kelch like family member 23 K10460 KLHL23; kelch-like protein 23
E 100017329 KLHL24; kelch like family member 24 K10461 KLHL24_35; kelch-like protein 24/35
E 100011909 KLHL35; kelch like family member 35 K10461 KLHL24_35; kelch-like protein 24/35
E 100013826 KLHL25; kelch like family member 25 K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 100011601 ENC1; ectodermal-neural cortex 1 K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 100027335 ectoderm-neural cortex protein 1-like K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 100015959 KLHL26; kelch like family member 26 K10463 KLHL26; kelch-like protein 26
E 100024315 IPP; intracisternal A particle-promoted polypeptide K13956 IPP; actin-binding protein IPP
E 100020578 KLHL28; kelch like family member 28 K10464 KLHL28; kelch-like protein 28
E 103106767 kelch-like protein 29 K10465 KLHL29; kelch-like protein 29
E 100021579 KLHL30; kelch like family member 30 K10466 KLHL30; kelch-like protein 30
E 100014419 KLHL31; kelch like family member 31 K10467 KLHL31; kelch-like protein 31
E 100026912 KLHL32; kelch like family member 32 K10468 KLHL32; kelch-like protein 32
E 100029530 KLHL33; kelch like family member 33 K13957 KLHL33; kelch-like protein 33
E 100013107 KLHL34; kelch like family member 34 K10469 KLHL34; kelch-like protein 34
E 100023505 KLHL36; kelch like family member 36 K13958 KLHL36; kelch-like protein 36
E 100032152 KLHL38; kelch like family member 38 K13959 KLHL38; kelch-like protein 38
E 100012995 KBTBD2; kelch repeat and BTB domain containing 2 K10470 KBTBD2; kelch repeat and BTB domain-containing protein 2
E 100032572 KBTBD3; kelch repeat and BTB domain containing 3 K10471 KBTBD3; kelch repeat and BTB domain-containing protein 3
E 100012695 KBTBD4; kelch repeat and BTB domain containing 4 K10472 KBTBD4; kelch repeat and BTB domain-containing protein 4
E 100026771 KLHL40; kelch like family member 40 K10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5/10
E 100024196 KLHL41; kelch like family member 41 K10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5/10
E 100014230 KBTBD7; kelch repeat and BTB domain-containing protein 7 K10474 KBTBD6_7; kelch repeat and BTB domain-containing protein 6/7
E 100618276 KBTBD8; kelch repeat and BTB domain containing 8 K10475 KBTBD8; kelch repeat and BTB domain-containing protein 8
E 100014592 kelch repeat and BTB domain-containing protein 8-like K10475 KBTBD8; kelch repeat and BTB domain-containing protein 8
E 100032500 KBTBD11; kelch repeat and BTB domain containing 11 K10476 KBTBD11; kelch repeat and BTB domain-containing protein 11
E 100027870 KBTBD12; kelch repeat and BTB domain containing 12 K21912 KBTBD12; kelch repeat and BTB domain-containing protein 12
E 100024021 KBTBD13; kelch repeat and BTB domain containing 13 K21913 KBTBD13; kelch repeat and BTB domain-containing protein 13
E 100018923 BTBD2; BTB domain containing 2 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 100010488 BTBD1; BTB domain containing 1 K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 100031621 BTBD3; BTB domain containing 3 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 100619848 BTBD6; BTB domain containing 6 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 100016931 BTBD7; BTB domain containing 7 K10479 BTBD7; BTB/POZ domain-containing protein 7
E 100026383 KIAA1107 ortholog K10480 BTBD8; BTB/POZ domain-containing protein 8
E 100029678 BTBD9; BTB domain containing 9 K10481 BTBD9; BTB/POZ domain-containing protein 9
E 100021708 BTBD10; BTB domain containing 10 K10482 BTBD10; BTB/POZ domain-containing protein 10
E 100015914 BTBD11; BTB domain containing 11 K10483 BTBD11; BTB/POZ domain-containing protein 11
E 100016277 SLX4; SLX4 structure-specific endonuclease subunit K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
E 100032715 GMCL1; germ cell-less, spermatogenesis associated 1 K10485 BTBD13; BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)
E 100018981 nucleus accumbens-associated protein 1 K10486 BTBD14; BTB/POZ domain-containing protein 14
E 100016365 NACC2; NACC family member 2 K10486 BTBD14; BTB/POZ domain-containing protein 14
E 100021158 NACC1; nucleus accumbens associated 1 K10486 BTBD14; BTB/POZ domain-containing protein 14
E 100619928 BTBD16; BTB domain containing 16 K10487 BTBD16; BTB/POZ domain-containing protein 16
E 100022506 ZBTB1; zinc finger and BTB domain containing 1 K10488 ZBTB1; zinc finger and BTB domain-containing protein 1
E 100027107 ZBTB2; zinc finger and BTB domain containing 2 K10489 ZBTB2; zinc finger and BTB domain-containing protein 2
E 100012474 ZBTB3; zinc finger and BTB domain containing 3 K10490 ZBTB3; zinc finger and BTB domain-containing protein 3
E 100014773 ZBTB4; zinc finger and BTB domain containing 4 K10491 ZBTB4; zinc finger and BTB domain-containing protein 4
E 100013428 ZBTB5; zinc finger and BTB domain containing 5 K10492 ZBTB5; zinc finger and BTB domain-containing protein 5
E 100017775 ZBTB6; zinc finger and BTB domain containing 6 K10493 ZBTB6; zinc finger and BTB domain-containing protein 6
E 100022367 ZBTB7A; zinc finger and BTB domain containing 7A K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 100019180 ZBTB7C; zinc finger and BTB domain containing 7C K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 100021459 ZBTB7B; zinc finger and BTB domain containing 7B K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E 100025816 ZBTB8A; zinc finger and BTB domain containing 8A K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
E 100032329 ZBTB8B; zinc finger and BTB domain containing 8B K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
E 100025535 ZBTB9; zinc finger and BTB domain containing 9 K10496 ZBTB9; zinc finger and BTB domain-containing protein 9
E 100026948 ZBTB10; zinc finger and BTB domain containing 10 K10497 ZBTB10; zinc finger and BTB domain-containing protein 10
E 100016429 ZBTB11; zinc finger and BTB domain containing 11 K10498 ZBTB11; zinc finger and BTB domain-containing protein 11
E 100025402 ZBTB12; zinc finger and BTB domain containing 12 K10499 ZBTB12; zinc finger and BTB domain-containing protein 12
E 100032135 ZBTB16; zinc finger and BTB domain containing 16 K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
E 100619919 ZBTB17; zinc finger and BTB domain containing 17 K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
E 100014362 ZBTB20; zinc finger and BTB domain containing 20 K10501 ZBTB20; zinc finger and BTB domain-containing protein 20
E 100027196 ZBTB22; zinc finger and BTB domain containing 22 K10502 ZBTB22; zinc finger and BTB domain-containing protein 22
E 100029135 ZBTB24; zinc finger and BTB domain containing 24 K10503 ZBTB24; zinc finger and BTB domain-containing protein 24
E 100022480 ZBTB25; zinc finger and BTB domain containing 25 K10504 ZBTB25; zinc finger and BTB domain-containing protein 25
E 100017837 ZBTB26; zinc finger and BTB domain containing 26 K10505 ZBTB26; zinc finger and BTB domain-containing protein 26
E 100617522 ZBTB32; zinc finger and BTB domain containing 32 K10506 ZBTB32; zinc finger and BTB domain-containing protein 32
E 100012169 ZBTB33; zinc finger and BTB domain containing 33 K10507 ZBTB33; zinc finger and BTB domain-containing protein 33
E 100020345 ZBTB34; zinc finger and BTB domain containing 34 K10508 ZBTB34; zinc finger and BTB domain-containing protein 34
E 100021116 ZBTB37; zinc finger and BTB domain containing 37 K10509 ZBTB37; zinc finger and BTB domain-containing protein 37
E 103096305 ZBTB38; zinc finger and BTB domain containing 38 K10510 ZBTB38; zinc finger and BTB domain-containing protein 38
E 100010190 ZBTB39; zinc finger and BTB domain containing 39 K10511 ZBTB39; zinc finger and BTB domain-containing protein 39
E 100616920 ZBTB40; zinc finger and BTB domain containing 40 K10512 ZBTB40; zinc finger and BTB domain-containing protein 40
E 100020580 ZBTB41; zinc finger and BTB domain containing 41 K10513 ZBTB41; zinc finger and BTB domain-containing protein 41
E 100620023 ZBTB43; zinc finger and BTB domain containing 43 K10514 ZBTB43; zinc finger and BTB domain-containing protein 43
E 100021721 ZBTB44; zinc finger and BTB domain containing 44 K10515 ZBTB44; zinc finger and BTB domain-containing protein 44
E 100019494 ZBTB46; zinc finger and BTB domain containing 46 K10517 ZBTB46; zinc finger and BTB domain-containing protein 46
E 100026850 ZBTB47; zinc finger and BTB domain containing 47 K10518 ZBTB47; zinc finger and BTB domain-containing protein 47
E 100617304 zinc finger and BTB domain-containing protein 48 K10519 ZBTB48; zinc finger and BTB domain-containing protein 48
E 100026896 ZBTB48; zinc finger and BTB domain containing 48 K10519 ZBTB48; zinc finger and BTB domain-containing protein 48
E 100016927 ABTB1; ankyrin repeat and BTB domain containing 1 K10520 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1
E 100023404 ABTB2; ankyrin repeat and BTB domain containing 2 K10521 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2
E 100030651 RHOBTB2; Rho related BTB domain containing 2 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 100018851 RHOBTB1; Rho related BTB domain containing 1 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 100010879 RHOBTB3; Rho related BTB domain containing 3 K07869 RHOBTB3; Rho-related BTB domain-containing protein 3
E 100019459 TNFAIP1; TNF alpha induced protein 1 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 100014022 KCTD13; potassium channel tetramerization domain containing 13 K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 100010674 KCTD1; potassium channel tetramerization domain containing 1 K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 100618638 KCTD15; potassium channel tetramerization domain containing 15 K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 100018762 KCTD5; potassium channel tetramerization domain containing 5 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 100025291 KCTD17; potassium channel tetramerization domain containing 17 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 100027673 KCTD2; potassium channel tetramerization domain containing 2 K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 100017246 KCTD3; potassium channel tetramerization domain containing 3 K21915 KCTD3; BTB/POZ domain-containing protein KCTD3
E 100010574 KCTD6; potassium channel tetramerization domain containing 6 K21916 KCTD6; BTB/POZ domain-containing protein KCTD6
E 100009842 KCTD7; potassium channel tetramerization domain containing 7 K21917 KCTD7_14; BTB/POZ domain-containing protein KCTD7/14
E 100027377 KCTD14; potassium channel tetramerization domain containing 14 K21917 KCTD7_14; BTB/POZ domain-containing protein KCTD7/14
E 100010822 KCTD12; potassium channel tetramerization domain containing 12 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 100015065 KCTD8; potassium channel tetramerization domain containing 8 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 100017359 BTB/POZ domain-containing protein KCTD12-like K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 100023376 KCTD16; potassium channel tetramerization domain containing 16 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 100019709 KCTD9; potassium channel tetramerization domain containing 9 K21919 KCTD9; BTB/POZ domain-containing protein KCTD9
E 100016304 KCTD11; potassium channel tetramerization domain containing 11 K21920 KCTD11; BTB/POZ domain-containing protein KCTD11 [EC:2.3.2.27]
E 100021892 BTB/POZ domain-containing protein KCTD11-like K21920 KCTD11; BTB/POZ domain-containing protein KCTD11 [EC:2.3.2.27]
E 100029933 KCTD18; potassium channel tetramerization domain containing 18 K21921 KCTD18; BTB/POZ domain-containing protein KCTD18
E 100017978 KCTD21; potassium channel tetramerization domain containing 21 K21922 KCTD21; BTB/POZ domain-containing protein KCTD21
E 100022080 DIABLO; diablo IAP-binding mitochondrial protein K10522 DIABLO; diablo
E 100021911 SPOP; speckle type BTB/POZ protein K10523 SPOP; speckle-type POZ protein
E 100012650 SPOPL; speckle type BTB/POZ protein like K10523 SPOP; speckle-type POZ protein
E 100027624 LZTR1; leucine zipper like transcription regulator 1 K23330 LZTR1; leucine-zipper-like transcriptional regulator 1
C Cul4 complex
D Ring finger protein
E 100013521 RBX1; ring-box 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 100016493 CUL4A; cullin 4A K10609 CUL4; cullin 4
E 100020368 CUL4B; cullin 4B K10609 CUL4; cullin 4
D Adoptor protein
E 100027158 DDB1; damage specific DNA binding protein 1 K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E 100016157 DDB2; damage specific DNA binding protein 2 K10140 DDB2; DNA damage-binding protein 2
E 100021792 DNA damage-binding protein 2-like K10140 DDB2; DNA damage-binding protein 2
E 100032223 ERCC8; ERCC excision repair 8, CSA ubiquitin ligase complex subunit K10570 ERCC8; DNA excision repair protein ERCC-8
E 100013553 DET1; de-etiolated homolog 1 (Arabidopsis) K10571 DET1; de-etiolated-1
E 100021432 RFWD2; ring finger and WD repeat domain 2 K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
E 100016230 DDA1; DET1 and DDB1 associated 1 K11792 DDA1; DET1- and DDB1-associated protein 1
E 100022278 CRBN; cereblon K11793 CRBN; cereblon
E 100032429 TRPC4AP; transient receptor potential cation channel subfamily C member 4 associated protein K11796 TRPC4AP; Trpc4-associated protein
E 100021242 DCAF1; DDB1 and CUL4 associated factor 1 K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
E 100016445 DTL; denticleless E3 ubiquitin protein ligase homolog K11790 DTL; denticleless
E 100024761 DCAF4; DDB1 and CUL4 associated factor 4 K11799 DCAF4; DDB1- and CUL4-associated factor 4
E 100028558 DCAF5; DDB1 and CUL4 associated factor 5 K11800 DCAF5; DDB1- and CUL4-associated factor 5
E 100013868 DCAF6; DDB1 and CUL4 associated factor 6 K11795 DCAF6; DDB1- and CUL4-associated factor 6
E 100021497 DCAF7; DDB1 and CUL4 associated factor 7 K11805 DCAF7; DDB1- and CUL4-associated factor 7
E 100023067 DCAF8; DDB1 and CUL4 associated factor 8 K11804 DCAF8; DDB1- and CUL4-associated factor 8
E 100012990 WDTC1; WD and tetratricopeptide repeats 1 K11807 WDTC1; WD and tetratricopeptide repeats protein 1
E 100019156 DCAF10; DDB1 and CUL4 associated factor 10 K11802 DCAF10; DDB1- and CUL4-associated factor 10
E 100030709 DCAF11; DDB1 and CUL4 associated factor 11 K11801 DCAF11; DDB1- and CUL4-associated factor 11
E 100010360 DCAF12; DDB1 and CUL4 associated factor 12 K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 100024061 DCAF13; DDB1 and CUL4 associated factor 13 K11806 DCAF13; DDB1- and CUL4-associated factor 13
E 100017685 PHIP; pleckstrin homology domain interacting protein K11797 PHIP; PH-interacting protein
E 100020864 DCAF15; DDB1 and CUL4 associated factor 15 K11791 DCAF15; DDB1- and CUL4-associated factor 15
E 100013839 DDB1- and CUL4-associated factor 15-like K11791 DCAF15; DDB1- and CUL4-associated factor 15
E 100024907 DCAF17; DDB1 and CUL4 associated factor 17 K23331 DCAF17; DDB1- and CUL4-associated factor 17
E 100017599 BRWD1; bromodomain and WD repeat domain containing 1 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 100021215 BRWD3; bromodomain and WD repeat domain containing 3 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 100018907 WDR26; WD repeat domain 26 K22382 WDR26; WD repeat-containing protein 26
E 100019680 WDR70; WD repeat domain 70 K24752 WDR70; WD repeat-containing protein 70
E 100012076 WDR76; WD repeat domain 76 K24755 WDR76; WD repeat-containing protein 76
C Cul5 complex
D Ring finger protein
E 100013833 RNF7; ring finger protein 7 K10611 RBX2; RING-box protein 2
D Cullin
E 100032484 CUL5; cullin 5 K10612 CUL5; cullin 5
D Adoptor protein
E 100028060 ELOC; elongin C K03872 ELOC; elongin-C
E 100018279 ELOB; elongin B K03873 ELOB; elongin-B
D Target recognizing subunit
E 100028873 CISH; cytokine inducible SH2 containing protein K04701 CISH; cytokine inducible SH2-containing protein
E 100616780 suppressor of cytokine signaling 1-like K04694 SOCS1; suppressor of cytokine signaling 1
E 100011895 SOCS2; suppressor of cytokine signaling 2 K04695 SOCS2; suppressor of cytokine signaling 2
E 100026656 SOCS3; suppressor of cytokine signaling 3 K04696 SOCS3; suppressor of cytokine signaling 3
E 100024207 SOCS4; suppressor of cytokine signaling 4 K04697 SOCS4; suppressor of cytokine signaling 4
E 100032188 SOCS5; suppressor of cytokine signaling 5 K04698 SOCS5; suppressor of cytokine signaling 5
E 100017282 SOCS7; suppressor of cytokine signaling 7 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 100015445 SOCS6; suppressor of cytokine signaling 6 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 100010716 ASB1; ankyrin repeat and SOCS box containing 1 K10323 ASB1; ankyrin repeat and SOCS box protein 1
E 100014676 ASB2; ankyrin repeat and SOCS box containing 2 K10324 ASB2; ankyrin repeat and SOCS box protein 2
E 100033342 ASB3; ankyrin repeat and SOCS box containing 3 K10325 ASB3; ankyrin repeat and SOCS box protein 3
E 100017758 ASB4; ankyrin repeat and SOCS box containing 4 K10326 ASB4; ankyrin repeat and SOCS box protein 4
E 100013385 ASB5; ankyrin repeat and SOCS box containing 5 K10327 ASB5; ankyrin repeat and SOCS box protein 5
E 100012778 ASB6; ankyrin repeat and SOCS box containing 6 K10328 ASB6; ankyrin repeat and SOCS box protein 6
E 100015307 ASB7; ankyrin repeat and SOCS box containing 7 K10329 ASB7; ankyrin repeat and SOCS box protein 7
E 100031828 ASB9; ankyrin repeat and SOCS box containing 9 K10331 ASB9; ankyrin repeat and SOCS box protein 9
E 100018403 ASB10; ankyrin repeat and SOCS box containing 10 K10332 ASB10; ankyrin repeat and SOCS box protein 10
E 100017204 ASB11; ankyrin repeat and SOCS box containing 11 K10333 ASB11; ankyrin repeat and SOCS box protein 11
E 100010866 ASB12; ankyrin repeat and SOCS box containing 12 K10334 ASB12; ankyrin repeat and SOCS box protein 12
E 100022724 ASB13; ankyrin repeat and SOCS box containing 13 K10335 ASB13; ankyrin repeat and SOCS box protein 13
E 100013617 ASB14; ankyrin repeat and SOCS box containing 14 K10336 ASB14; ankyrin repeat and SOCS box protein 14
E 100013482 ASB15; ankyrin repeat and SOCS box containing 15 K10337 ASB15; ankyrin repeat and SOCS box protein 15
E 100019661 ASB16; ankyrin repeat and SOCS box containing 16 K10338 ASB16; ankyrin repeat and SOCS box protein 16
E 100014435 ASB17; ankyrin repeat and SOCS box containing 17 K10339 ASB17; ankyrin repeat and SOCS box protein 17
E 100010902 ASB18; ankyrin repeat and SOCS box containing 18 K10340 ASB18; ankyrin repeat and SOCS box protein 18
E 100023969 WSB1; WD repeat and SOCS box containing 1 K10341 WSB1; WD repeat and SOCS box-containing protein 1
E 100023636 WSB2; WD repeat and SOCS box containing 2 K10342 WSB2; WD repeat and SOCS box-containing protein 2
E 100009731 SPSB1; splA/ryanodine receptor domain and SOCS box containing 1 K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 100017865 SPSB4; splA/ryanodine receptor domain and SOCS box containing 4 K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 100011333 SPSB3; splA/ryanodine receptor domain and SOCS box containing 3 K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 100016742 RAB40C; RAB40C, member RAS oncogene family K07928 RAB40; Ras-related protein Rab-40
E 100024044 LRRC41; leucine rich repeat containing 41 K10347 LRRC41; leucine-rich repeat-containing protein 41
E 100015903 RSPRY1; ring finger and SPRY domain containing 1 K23332 RSPRY1; RING finger and SPRY domain-containing protein 1
E 100021676 ANKRD9; ankyrin repeat domain 9 K25208 ANKRD9; ankyrin repeat domain-containing protein 9
E 100029002 KLHDC1; kelch domain containing 1 K25810 KLHDC1; kelch domain-containing protein 1
C Cul7 complex
D Ring finger protein
E 100013521 RBX1; ring-box 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E 100014810 SKP1; S-phase kinase associated protein 1 K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
E 100023212 FBXW8; F-box and WD repeat domain containing 8 K10264 FBXW8; F-box and WD-40 domain protein 8
C Cul8 complex
D Ring finger protein
E 100013521 RBX1; ring-box 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E 100013521 RBX1; ring-box 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 100011162 CUL9; cullin 9 K11970 CUL9; cullin 9
C APC/C
D Ring finger protein
E 100025534 ANAPC11; anaphase promoting complex subunit 11 K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E 100023440 ANAPC2; anaphase promoting complex subunit 2 K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E 100010404 FZR1; fizzy/cell division cycle 20 related 1 K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
E 100027495 fizzy-related protein homolog K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E 100031108 ANAPC1; anaphase promoting complex subunit 1 K03348 APC1; anaphase-promoting complex subunit 1
E 100025278 CDC27; cell division cycle 27 K03350 APC3; anaphase-promoting complex subunit 3
E 100012855 ANAPC4; anaphase promoting complex subunit 4 K03351 APC4; anaphase-promoting complex subunit 4
E 100015868 ANAPC5; anaphase promoting complex subunit 5 K03352 APC5; anaphase-promoting complex subunit 5
E 100016016 CDC16; cell division cycle 16 K03353 APC6; anaphase-promoting complex subunit 6
E 100020392 ANAPC7; anaphase promoting complex subunit 7 K03354 APC7; anaphase-promoting complex subunit 7
E 100024960 CDC23; cell division cycle 23 K03355 APC8; anaphase-promoting complex subunit 8
E 100019010 ANAPC10; anaphase promoting complex subunit 10 K03357 APC10; anaphase-promoting complex subunit 10
E 100016215 ANAPC13; anaphase promoting complex subunit 13 K12456 APC13; anaphase-promoting complex subunit 13
E 100013043 ANAPC15; anaphase promoting complex subunit 15 K25228 APC15; anaphase-promoting complex subunit 15
E 100009794 ANAPC16; anaphase promoting complex subunit 16 K25229 APC16; anaphase-promoting complex subunit 16
C BRCC complex
D 554178 BRCA1; BRCA1, DNA repair associated K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
D 100049015 BRCA2; BRCA2, DNA repair associated K08775 BRCA2; breast cancer 2 susceptibility protein
D 100014766 BRCC3; BRCA1/BRCA2-containing complex subunit 3 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 100010162 lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 100014337 BARD1; BRCA1 associated RING domain 1 K10683 BARD1; BRCA1-associated RING domain protein 1
D 100026430 BRE; brain and reproductive organ-expressed (TNFRSF1A modulator) K12173 BRE; BRCA1-A complex subunit BRE
D 100027424 RAD51; RAD51 recombinase K04482 RAD51; DNA repair protein RAD51
C KPC complex
D 100028024 RNF123; ring finger protein 123 K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D 100016443 UBAC1; UBA domain containing 1 K12174 KPC2; Kip1 ubiquitination-promoting complex protein 2
C LUBAC complex
D 100017663 SHARPIN; SHANK associated RH domain interactor K20894 SHARPIN; shank-associated RH domain-interacting protein
D 100011102 RBCK1; RANBP2-type and C3HC4-type zinc finger containing 1 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 100030741 RNF31; ring finger protein 31 K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
C CTLH complex
D 100018042 RMND5A; required for meiotic nuclear division 5 homolog A K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 100027948 RMND5B; required for meiotic nuclear division 5 homolog B K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 100026422 RANBP9; RAN binding protein 9 K23334 RANBP9_10; Ran-binding protein 9/10
D 100021429 RANBP10; RAN binding protein 10 K23334 RANBP9_10; Ran-binding protein 9/10
D 100024322 ARMC8; armadillo repeat containing 8 K23336 ARMC8; armadillo repeat-containing protein 8
D 100015982 MKLN1; muskelin 1 K23337 MKLN1; muskelin
D 100016372 MAEA; macrophage erythroblast attacher K18624 MAEA; macrophage erythroblast attacher
D 100029505 GID4; GID complex subunit 4 homolog K23335 GID4; glucose-induced degradation protein 4
D 100020243 GID8; GID complex subunit 8 homolog K23338 GID8; glucose-induced degradation protein 8
D 100026679 YPEL5; yippee like 5 K23339 YPEL5; protein yippee-like 5
D 100018907 WDR26; WD repeat domain 26 K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
D 100015225 AMFR; autocrine motility factor receptor K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 100018213 TMUB1; transmembrane and ubiquitin like domain containing 1 K23340 TMUB; transmembrane and ubiquitin-like domain-containing protein
D 100022931 TMUB2; transmembrane and ubiquitin like domain containing 2 K23340 TMUB; transmembrane and ubiquitin-like domain-containing protein
D 100027753 ERLIN1; ER lipid raft associated 1 K23341 ERLIN; erlin
D 100032930 ERLIN2; ER lipid raft associated 2 K23341 ERLIN; erlin
C LMBR1L-GP78-UBAC2 complex
D 100010133 LMBR1L; limb development membrane protein 1 like K25215 LMBR1L; protein LMBR1L
D 100015225 AMFR; autocrine motility factor receptor K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 100026358 UBAC2; UBA domain containing 2 K25216 UBAC2; ubiquitin-associated domain-containing protein 2
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D 100009925 CAND1; cullin associated and neddylation dissociated 1 K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D 100015450 CAND2; cullin associated and neddylation dissociated 2 (putative) K24172 CAND2; cullin-associated NEDD8-dissociated protein 2
D 100033316 COMMD1; copper metabolism domain containing 1 K22557 COMMD1; COMM domain containing 1
D 100012201 COMMD2; COMM domain containing 2 K22558 COMMD2; COMM domain containing 2
D 103103863 COMMD3; COMM domain containing 3 K22559 COMMD3; COMM domain containing 3
D 100030348 COMMD4; COMM domain containing 4 K22560 COMMD4; COMM domain containing 4
D 103094473 COMM domain-containing protein 5-like K22561 COMMD5; COMM domain containing 5
D 100012143 COMMD6; COMM domain containing 6 K22562 COMMD6; COMM domain containing 6
D 100013789 COMM domain-containing protein 6-like K22562 COMMD6; COMM domain containing 6
D 100009837 COMMD7; COMM domain containing 7 K22563 COMMD7; COMM domain containing 7
D 100014498 COMMD8; COMM domain containing 8 K22564 COMMD8; COMM domain containing 8
D 100010642 COMMD9; COMM domain containing 9 K22565 COMMD9; COMM domain containing 9
D 100029172 COMMD10; COMM domain containing 10 K22566 COMMD10; COMM domain containing 10
D 100018188 DDRGK1; DDRGK domain containing 1 K23344 DDRGK1; DDRGK domain-containing protein 1
D 100026329 GLMN; glomulin, FKBP associated protein K23345 GLMN; glomulin
D 100018976 IVNS1ABP; influenza virus NS1A binding protein K15046 IVNS1ABP; influenza virus NS1A-binding protein
D 100021971 UBXN7; UBX domain protein 7 K24350 UBXN7; UBX domain-containing protein 7
D 100028118 PACRG; PARK2 coregulated K26163 PACRG; parkin coregulated gene protein
D 100015516 UBAP2L; ubiquitin associated protein 2 like K26545 UBAP2; ubiquitin-associated protein 2
D 100011549 UBAP2; ubiquitin associated protein 2 K26545 UBAP2; ubiquitin-associated protein 2
#
ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D 100015629 UCHL1; ubiquitin C-terminal hydrolase L1 K05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
D 100030960 BAP1; BRCA1 associated protein 1 K08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
D 100012187 UCHL3; ubiquitin C-terminal hydrolase L3 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D 100019909 UCHL5; ubiquitin C-terminal hydrolase L5 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D 100014031 CYLD; CYLD lysine 63 deubiquitinase K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
D 100031700 USP1; ubiquitin specific peptidase 1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D 100024409 USP2; ubiquitin specific peptidase 2 K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D 100016993 USP3; ubiquitin specific peptidase 3 K11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]
D 100021067 USP4; ubiquitin specific peptidase 4 K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D 100017905 USP11; ubiquitin specific peptidase 11 K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D 100013861 USP13; ubiquitin specific peptidase 13 (isopeptidase T-3) K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 100016245 USP5; ubiquitin specific peptidase 5 K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 100619043 USP32; ubiquitin specific peptidase 32 K11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12]
D 100018496 USP7; ubiquitin specific peptidase 7 K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 100026038 USP8; ubiquitin specific peptidase 8 K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D 100017331 USP9X; ubiquitin specific peptidase 9, X-linked K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 100032405 USP24; ubiquitin specific peptidase 24 K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 100023556 USP10; ubiquitin specific peptidase 10 K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D 100619289 ubiquitin carboxyl-terminal hydrolase 10-like K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D 100018316 USP46; ubiquitin specific peptidase 46 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 100024908 USP12; ubiquitin specific peptidase 12 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 100017337 ubiquitin carboxyl-terminal hydrolase 12-like K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 100013535 USP14; ubiquitin specific peptidase 14 K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D 100012616 USP15; ubiquitin specific peptidase 15 K21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]
D 100020701 USP45; ubiquitin specific peptidase 45 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 100020904 USP16; ubiquitin specific peptidase 16 K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 100617573 ubiquitin carboxyl-terminal hydrolase 16-like K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 100022228 USP18; ubiquitin specific peptidase 18 K11846 USP18_41; ubiquitin carboxyl-terminal hydrolase 18/41 [EC:3.4.19.12]
D 100020891 USP19; ubiquitin specific peptidase 19 K11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]
D 100013034 USP20; ubiquitin specific peptidase 20 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 100028924 USP21; ubiquitin specific peptidase 21 K21634 USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]
D 100017232 USP22; ubiquitin specific peptidase 22 K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 100013612 USP25; ubiquitin specific peptidase 25 K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
D 100011373 USP37; ubiquitin specific peptidase 37 K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12]
D 100032176 USP28; ubiquitin specific peptidase 28 K21122 USP28; ubiquitin carboxyl-terminal hydrolase 28 [EC:3.4.19.12]
D 100023987 USP30; ubiquitin specific peptidase 30 K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]
D 100027645 USP31; ubiquitin specific peptidase 31 K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]
D 100033319 USP34; ubiquitin specific peptidase 34 K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
D 100017939 USP35; ubiquitin specific peptidase 35 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 100019234 USP38; ubiquitin specific peptidase 38 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 100026585 USP36; ubiquitin specific peptidase 36 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 100027137 USP42; ubiquitin specific peptidase 42 K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D 100025361 USP40; ubiquitin specific peptidase 40 K11869 USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12]
D 100618373 USP43; ubiquitin specific peptidase 43 K11856 USP43; ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12]
D 100030401 USP49; ubiquitin specific peptidase 49 K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
D 100017189 USP44; ubiquitin specific peptidase 44 K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
D 100030068 USP47; ubiquitin specific peptidase 47 K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]
D 100023231 USP48; ubiquitin specific peptidase 48 K11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]
C OTU
D 100016172 ubiquitin thioesterase OTUB1 K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
D 100017339 OTUB2; OTU deubiquitinase, ubiquitin aldehyde binding 2 K09603 OTUB2; ubiquitin thioesterase protein OTUB2 [EC:3.4.19.12]
D 100027507 OTUD3; OTU deubiquitinase 3 K13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]
D 100029512 OTUD6B; OTU domain containing 6B K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 100026622 IFNAR1; interferon alpha and beta receptor subunit 1 K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 100021938 OTUD7A; OTU deubiquitinase 7A K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
D 100014166 OTUD7B; OTU deubiquitinase 7B K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
D 100020448 OTULIN; OTU deubiquitinase with linear linkage specificity K18343 OTULIN; ubiquitin thioesterase otulin [EC:3.4.19.12]
D 100025842 TNFAIP3; TNF alpha induced protein 3 K11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
D 100029187 VCPIP1; valosin containing protein interacting protein 1 K11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12]
D 100009838 ZRANB1; zinc finger RANBP2-type containing 1 K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
C MJD
D 100014030 ATXN3; ataxin 3 K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D 100010912 JOSD1; Josephin domain containing 1 K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D 100017737 FAM63A; family with sequence similarity 63 member A K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D 100027277 FAM63B; family with sequence similarity 63 member B K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D 100020615 FAM188A; family with sequence similarity 188 member A K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 103095783 FAM188B; family with sequence similarity 188 member B K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 103095369 protein FAM188B-like K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 103106102 protein FAM188B2 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
C JAMM
D 100014766 BRCC3; BRCA1/BRCA2-containing complex subunit 3 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 100010162 lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 100032055 MYSM1; Myb like, SWIRM and MPN domains 1 K11865 MYSM1; histone H2A deubiquitinase [EC:3.4.19.-]
D 100022880 MPND; MPN domain containing K24173 MPND; MPN domain-containing protein
D 100015662 PSMD14; proteasome 26S subunit, non-ATPase 14 K03030 PSMD14; 26S proteasome regulatory subunit N11
D 100023713 STAMBP; STAM binding protein K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
D 100021302 STAMBPL1; AMSH-like protease K11867 STAMBPL1; AMSH-like protease [EC:3.4.19.12]
C PPPDE
D 100020033 DESI2; desumoylating isopeptidase 2 K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
D 103093231 desumoylating isopeptidase 2-like K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
D 100029965 ZUFSP; zinc finger with UFM1 specific peptidase domain K24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]
C BRISC complex
D 100010372 FAM175B; family with sequence similarity 175 member B K20799 FAM175B; BRISC complex subunit Abro1
D 100016075 BABAM1; BRISC and BRCA1 A complex member 1 K20776 BABAM; BRISC and BRCA1-A complex member 1
D 100014766 BRCC3; BRCA1/BRCA2-containing complex subunit 3 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 100010162 lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 100026430 BRE; brain and reproductive organ-expressed (TNFRSF1A modulator) K12173 BRE; BRCA1-A complex subunit BRE
B UBL-specific proteases (ULPs)
C 103099737 SENP2; SUMO1/sentrin/SMT3 specific peptidase 2 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
C 100015849 SENP3; SUMO1/sentrin/SMT3 specific peptidase 3 K08593 SENP3; sentrin-specific protease 3 [EC:3.4.22.68]
C 100021128 SENP5; SUMO1/sentrin specific peptidase 5 K08594 SENP5; sentrin-specific protease 5 [EC:3.4.22.68]
C 100022054 SENP6; SUMO1/sentrin specific peptidase 6 K08595 SENP6; sentrin-specific protease 6 [EC:3.4.22.68]
C 100016689 SENP7; SUMO1/sentrin specific peptidase 7 K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C 100013705 SENP8; SUMO/sentrin peptidase family member, NEDD8 specific K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C 100012187 UCHL3; ubiquitin C-terminal hydrolase L3 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C 100013308 DESI1; desumoylating isopeptidase 1 K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C 100026096 USPL1; ubiquitin specific peptidase like 1 K23008 USPL1; SUMO-specific isopeptidase USPL1 [EC:3.4.22.-]
C COP9 signalosome (CSN) complex
D 100025216 GPS1; G protein pathway suppressor 1 K12175 GPS1; COP9 signalosome complex subunit 1
D 100031162 COPS2; COP9 signalosome subunit 2 K12176 COPS2; COP9 signalosome complex subunit 2
D 100009845 COPS3; COP9 signalosome subunit 3 K12177 COPS3; COP9 signalosome complex subunit 3
D 100017037 COPS4; COP9 signalosome subunit 4 K12178 COPS4; COP9 signalosome complex subunit 4
D 100021238 COPS5; COP9 signalosome subunit 5 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D 100019239 COPS6; COP9 signalosome subunit 6 K12179 COPS6; COP9 signalosome complex subunit 6
D 100018050 COP9 signalosome complex subunit 6 K12179 COPS6; COP9 signalosome complex subunit 6
D 100013524 COPS7A; COP9 signalosome subunit 7A K12180 COPS7; COP9 signalosome complex subunit 7
D 100011257 COPS7B; COP9 signalosome subunit 7B K12180 COPS7; COP9 signalosome complex subunit 7
D 100010441 COPS8; COP9 signalosome subunit 8 K12181 COPS8; COP9 signalosome complex subunit 8
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 5, 2024