+D GENES KO #

  KEGG Orthology (KO) - Methanocaldococcus fervens

% ! A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:mfe00010] D Mefer_1516 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Mefer_1517 ADP-specific phosphofructokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147] D Mefer_0560 protein of unknown function DUF100 K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D Mefer_0658 Fructose-bisphosphate aldolase K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11] D Mefer_1187 predicted phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D Mefer_1530 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Mefer_0809 glyceraldehyde-3-phosphate dehydrogenase, type II K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59] D Mefer_0256 Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Mefer_1510 phosphonopyruvate decarboxylase-related protein K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Mefer_0447 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Mefer_0345 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Mefer_0788 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Mefer_0246 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Mefer_0884 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Mefer_0883 thiamine pyrophosphate protein domain protein TPP-binding K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Mefer_0886 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Mefer_0885 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Mefer_0139 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Mefer_0783 thiamine pyrophosphate protein domain protein TPP-binding K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Mefer_0312 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Mefer_1374 acetyl coenzyme A synthetase (ADP forming), alpha domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D Mefer_0232 Aldehyde ferredoxin oxidoreductase K11389 gapor; glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) [EC:1.2.7.6] C 00020 Citrate cycle (TCA cycle) [PATH:mfe00020] D Mefer_0246 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Mefer_0139 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Mefer_0783 thiamine pyrophosphate protein domain protein TPP-binding K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Mefer_0782 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3] D Mefer_0499 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3] D Mefer_0375 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Mefer_0470 succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Mefer_0096 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D Mefer_0211 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D Mefer_0722 Malate dehydrogenase (NADP(+)) K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Mefer_0577 acetyl-CoA carboxylase, biotin carboxylase K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1] D Mefer_0576 oxaloacetate decarboxylase alpha subunit K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1] D Mefer_0884 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Mefer_0883 thiamine pyrophosphate protein domain protein TPP-binding K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Mefer_0886 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Mefer_0885 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] C 00030 Pentose phosphate pathway [PATH:mfe00030] D Mefer_1516 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Mefer_0618 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D Mefer_0617 Transketolase domain protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D Mefer_0619 Transketolase central region K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D Mefer_0846 transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D Mefer_1518 ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D Mefer_1012 Formaldehyde-activating enzyme (Fae) K13812 fae-hps; bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43] D Mefer_0259 Dimethylmenaquinone methyltransferase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43] D Mefer_0374 6-phospho 3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D Mefer_1167 translation initiation factor, aIF-2BII family K18237 K18237; ribose 1,5-bisphosphate isomerase [EC:5.3.1.29] D Mefer_1352 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Mefer_0560 protein of unknown function DUF100 K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D Mefer_0658 Fructose-bisphosphate aldolase K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11] D Mefer_1187 predicted phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D Mefer_1517 ADP-specific phosphofructokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147] C 00040 Pentose and glucuronate interconversions [PATH:mfe00040] D Mefer_0525 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Mefer_0534 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Mefer_0618 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D Mefer_0115 class II aldolase/adducin family protein K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] C 00051 Fructose and mannose metabolism [PATH:mfe00051] D Mefer_1188 Phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8] D Mefer_0115 class II aldolase/adducin family protein K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] D Mefer_0560 protein of unknown function DUF100 K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D Mefer_0658 Fructose-bisphosphate aldolase K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11] D Mefer_1187 predicted phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D Mefer_1530 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 00052 Galactose metabolism [PATH:mfe00052] D Mefer_0469 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Mefer_0534 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] C 00053 Ascorbate and aldarate metabolism D Mefer_0525 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] C 00500 Starch and sucrose metabolism [PATH:mfe00500] D Mefer_0534 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Mefer_1515 Starch synthase K00703 glgA; starch synthase [EC:2.4.1.21] D Mefer_1323 alpha-glucan phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1] D Mefer_1511 Alpha-amylase K07405 E3.2.1.1A; alpha-amylase [EC:3.2.1.1] D Mefer_1516 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:mfe00520] D Mefer_0113 glucosamine/fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Mefer_0779 Phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10] D Mefer_0780 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D Mefer_0902 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D Mefer_1294 nucleotide sugar dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336] D Mefer_0524 NAD-dependent epimerase/dehydratase K08678 UXS1; UDP-glucuronate decarboxylase [EC:4.1.1.35] D Mefer_0534 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Mefer_0525 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Mefer_0469 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Mefer_1516 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Mefer_1188 Phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8] C 00620 Pyruvate metabolism [PATH:mfe00620] D Mefer_0312 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Mefer_0884 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Mefer_0883 thiamine pyrophosphate protein domain protein TPP-binding K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Mefer_0886 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Mefer_0885 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Mefer_0139 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Mefer_0783 thiamine pyrophosphate protein domain protein TPP-binding K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Mefer_0246 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Mefer_0345 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Mefer_1613 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D Mefer_1374 acetyl coenzyme A synthetase (ADP forming), alpha domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D Mefer_1317 Aldehyde Dehydrogenase K19266 E1.2.1.22; lactaldehyde dehydrogenase [EC:1.2.1.22] D Mefer_1465 beta-lactamase domain protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D Mefer_0577 acetyl-CoA carboxylase, biotin carboxylase K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1] D Mefer_0576 oxaloacetate decarboxylase alpha subunit K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1] D Mefer_0722 Malate dehydrogenase (NADP(+)) K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Mefer_0096 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D Mefer_0211 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D Mefer_0788 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Mefer_1483 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Mefer_0244 isopropylmalate/citramalate/homocitrate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] D Mefer_0710 isopropylmalate/citramalate/homocitrate synthase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:mfe00630] D Mefer_0312 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Mefer_0722 Malate dehydrogenase (NADP(+)) K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Mefer_1483 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Mefer_1318 ribulose bisphosphate carboxylase, type III K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39] D Mefer_0175 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Mefer_0958 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Mefer_0246 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00640 Propanoate metabolism [PATH:mfe00640] D Mefer_0312 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Mefer_1374 acetyl coenzyme A synthetase (ADP forming), alpha domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D Mefer_0246 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Mefer_0884 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Mefer_0883 thiamine pyrophosphate protein domain protein TPP-binding K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Mefer_0886 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Mefer_0885 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Mefer_0470 succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Mefer_0375 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] C 00650 Butanoate metabolism [PATH:mfe00650] D Mefer_1483 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Mefer_0884 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Mefer_0883 thiamine pyrophosphate protein domain protein TPP-binding K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Mefer_0886 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Mefer_0885 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Mefer_0139 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Mefer_0783 thiamine pyrophosphate protein domain protein TPP-binding K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Mefer_1482 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D Mefer_0954 thiamine pyrophosphate protein domain protein TPP-binding K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Mefer_0138 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Mefer_0195 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] C 00660 C5-Branched dibasic acid metabolism [PATH:mfe00660] D Mefer_0954 thiamine pyrophosphate protein domain protein TPP-binding K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Mefer_0138 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Mefer_0195 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Mefer_0470 succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Mefer_0375 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Mefer_0142 isopropylmalate/citramalate/homocitrate synthase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21] D Mefer_0713 homoaconitate hydratase family protein K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Mefer_0041 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Mefer_1072 isopropylmalate/isohomocitrate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] C 00562 Inositol phosphate metabolism [PATH:mfe00562] D Mefer_0344 Inositol-phosphate phosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Mefer_1530 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:mfe00190] D Mefer_0464 ATP synthase, A subunit K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] D Mefer_0465 ATP synthase, B subunit K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B D Mefer_0462 ATP synthase A1, C subunit K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C D Mefer_0213 V-type ATPase, D subunit K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D D Mefer_0461 H+transporting two-sector ATPase E subunit K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E D Mefer_0463 Vacuolar H+transporting two-sector ATPase F subunit K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F D Mefer_0458 ATP synthase H subunit K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H D Mefer_0459 V-type ATPase 116 kDa subunit K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I D Mefer_0460 H(+)-transporting two-sector ATPase K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K D Mefer_0580 plasma-membrane proton-efflux P-type ATPase K01535 PMA1; H+-transporting ATPase [EC:7.1.2.1] D Mefer_0226 Inorganic diphosphatase K15986 ppaC; manganese-dependent inorganic pyrophosphatase [EC:3.6.1.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation in photosynthetic organisms C 00720 Carbon fixation pathways in prokaryotes [PATH:mfe00720] D Mefer_0884 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Mefer_0883 thiamine pyrophosphate protein domain protein TPP-binding K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Mefer_0886 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Mefer_0885 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Mefer_0788 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Mefer_0577 acetyl-CoA carboxylase, biotin carboxylase K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1] D Mefer_0576 oxaloacetate decarboxylase alpha subunit K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1] D Mefer_0722 Malate dehydrogenase (NADP(+)) K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Mefer_0096 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D Mefer_0211 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D Mefer_1238 fumarate reductase/succinate dehydrogenase flavoprotein domain protein K18209 tfrA; fumarate reductase (CoM/CoB) subunit A [EC:1.3.4.1] D Mefer_0390 succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 tfrB; fumarate reductase (CoM/CoB) subunit B [EC:1.3.4.1] D Mefer_0375 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Mefer_0470 succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Mefer_1483 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Mefer_0139 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Mefer_0783 thiamine pyrophosphate protein domain protein TPP-binding K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Mefer_0782 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3] D Mefer_0499 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3] D Mefer_0881 4Fe-4S ferredoxin iron-sulfur binding domain protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D Mefer_0882 4Fe-4S ferredoxin iron-sulfur binding domain protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D Mefer_0824 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245] D Mefer_0823 CO dehydrogenase/acetyl-CoA synthase, delta subunit K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245] D Mefer_0312 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] C 00680 Methane metabolism [PATH:mfe00680] D Mefer_0653 formate dehydrogenase, alpha subunit K22516 fdhA; formate dehydrogenase (coenzyme F420) alpha subunit [EC:1.17.98.3 1.8.98.6] D Mefer_1009 molybdopterin oxidoreductase K22516 fdhA; formate dehydrogenase (coenzyme F420) alpha subunit [EC:1.17.98.3 1.8.98.6] D Mefer_0654 coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein K00125 fdhB; formate dehydrogenase (coenzyme F420) beta subunit [EC:1.17.98.3 1.8.98.6] D Mefer_0203 CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit K00192 cdhA; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit alpha [EC:1.2.7.4] D Mefer_0202 CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit K00195 cdhB; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit epsilon D Mefer_0200 CO dehydrogenase/acetyl-CoA synthase complex, beta subunit K00193 cdhC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit beta [EC:2.3.1.169] D Mefer_0824 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245] D Mefer_0823 CO dehydrogenase/acetyl-CoA synthase, delta subunit K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245] D Mefer_0881 4Fe-4S ferredoxin iron-sulfur binding domain protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D Mefer_0882 4Fe-4S ferredoxin iron-sulfur binding domain protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D Mefer_0958 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Mefer_0447 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Mefer_0722 Malate dehydrogenase (NADP(+)) K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Mefer_0560 protein of unknown function DUF100 K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D Mefer_0658 Fructose-bisphosphate aldolase K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11] D Mefer_1187 predicted phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D Mefer_1517 ADP-specific phosphofructokinase K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147] D Mefer_0374 6-phospho 3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D Mefer_0259 Dimethylmenaquinone methyltransferase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43] D Mefer_1012 Formaldehyde-activating enzyme (Fae) K13812 fae-hps; bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43] D Mefer_0155 formylmethanofuran dehydrogenase subunit A K00200 fwdA; formylmethanofuran dehydrogenase subunit A [EC:1.2.7.12] D Mefer_0243 formylmethanofuran dehydrogenase subunit B K00201 fwdB; formylmethanofuran dehydrogenase subunit B [EC:1.2.7.12] D Mefer_0153 formylmethanofuran dehydrogenase subunit C K00202 fwdC; formylmethanofuran dehydrogenase subunit C [EC:1.2.7.12] D Mefer_0156 molydopterin dinucleotide-binding region K00203 fwdD; formylmethanofuran dehydrogenase subunit D [EC:1.2.7.12] D Mefer_0159 4Fe-4S ferredoxin iron-sulfur binding domain protein K00204 fwdH; 4Fe-4S ferredoxin D Mefer_0158 4Fe-4S ferredoxin iron-sulfur binding domain protein K00205 fwdF; 4Fe-4S ferredoxin D Mefer_0157 4Fe-4S ferredoxin iron-sulfur binding domain protein K11260 fwdG; 4Fe-4S ferredoxin D Mefer_0555 formylmethanofuran dehydrogenase subunit E region K11261 fwdE; formylmethanofuran dehydrogenase subunit E [EC:1.2.7.12] D Mefer_1275 formylmethanofuran/tetrahydromethanopterin N-formyltransferase K00672 ftr; formylmethanofuran--tetrahydromethanopterin N-formyltransferase [EC:2.3.1.101] D Mefer_1327 methenyltetrahydromethanopterin cyclohydrolase K01499 mch; methenyltetrahydromethanopterin cyclohydrolase [EC:3.5.4.27] D Mefer_1257 Methylenetetrahydromethanopterin dehydrogenase K00319 mtd; methylenetetrahydromethanopterin dehydrogenase [EC:1.5.98.1] D Mefer_1242 coenzyme F420 hydrogenase, subunit alpha K00440 frhA; coenzyme F420 hydrogenase subunit alpha [EC:1.12.98.1] D Mefer_1239 coenzyme F420 hydrogenase, subunit beta K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1] D Mefer_0177 Coenzyme F420 hydrogenase K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1] D Mefer_0104 coenzyme F420-reducing hydrogenase delta subunit K00442 frhD; coenzyme F420 hydrogenase subunit delta D Mefer_1241 coenzyme F420-reducing hydrogenase delta subunit K00442 frhD; coenzyme F420 hydrogenase subunit delta D Mefer_1240 coenzyme F420 hydrogenase, subunit gamma K00443 frhG; coenzyme F420 hydrogenase subunit gamma [EC:1.12.98.1] D Mefer_0990 coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase K13942 hmd; 5,10-methenyltetrahydromethanopterin hydrogenase [EC:1.12.98.2] D Mefer_1535 5,10-methylenetetrahydromethanopterin reductase K00320 mer; 5,10-methylenetetrahydromethanopterin reductase [EC:1.5.98.2] D Mefer_0943 tetrahydromethanopterin S-methyltransferase, subunit A K00577 mtrA; tetrahydromethanopterin S-methyltransferase subunit A [EC:7.2.1.4] D Mefer_0944 tetrahydromethanopterin S-methyltransferase, subunit A K00577 mtrA; tetrahydromethanopterin S-methyltransferase subunit A [EC:7.2.1.4] D Mefer_0942 Tetrahydromethanopterin S-methyltransferase K00578 mtrB; tetrahydromethanopterin S-methyltransferase subunit B [EC:7.2.1.4] D Mefer_0941 tetrahydromethanopterin S-methyltransferase, subunit C K00579 mtrC; tetrahydromethanopterin S-methyltransferase subunit C [EC:7.2.1.4] D Mefer_0940 tetrahydromethanopterin S-methyltransferase, subunit D K00580 mtrD; tetrahydromethanopterin S-methyltransferase subunit D [EC:7.2.1.4] D Mefer_0939 tetrahydromethanopterin S-methyltransferase, subunit E K00581 mtrE; tetrahydromethanopterin S-methyltransferase subunit E [EC:7.2.1.4] D Mefer_0945 tetrahydromethanopterin S-methyltransferase, subunit G K00583 mtrG; tetrahydromethanopterin S-methyltransferase subunit G [EC:7.2.1.4] D Mefer_0946 tetrahydromethanopterin S-methyltransferase, MtrH subunit K00584 mtrH; tetrahydromethanopterin S-methyltransferase subunit H [EC:7.2.1.4] D Mefer_0938 methyl-coenzyme M reductase, alpha subunit K00399 mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1] D Mefer_0379 methyl coenzyme M reductase system, component A2 K00400 K00400; methyl coenzyme M reductase system, component A2 D Mefer_0959 ABC transporter related K00400 K00400; methyl coenzyme M reductase system, component A2 D Mefer_0934 methyl-coenzyme M reductase, beta subunit K00401 mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1] D Mefer_0937 methyl-coenzyme M reductase, gamma subunit K00402 mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1] D Mefer_0936 methyl-coenzyme M reductase I operon protein C K03421 mcrC; methyl-coenzyme M reductase subunit C D Mefer_0817 methyl-coenzyme M reductase operon protein D K03422 mcrD; methyl-coenzyme M reductase subunit D D Mefer_0935 methyl-coenzyme M reductase operon protein D K03422 mcrD; methyl-coenzyme M reductase subunit D D Mefer_0237 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D Mefer_1123 CoB/CoM heterodisulfide reductase, subunit B K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D Mefer_1124 CoB/CoM heterodisulfide reductase, subunit C K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D Mefer_1062 CoB/CoM heterodisulfide reductase, subunit C K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D Mefer_0238 methyl-viologen-reducing hydrogenase delta subunit K14127 mvhD; F420-non-reducing hydrogenase iron-sulfur subunit [EC:1.12.99.- 1.8.98.5 1.8.98.6] D Mefer_0240 nickel-dependent hydrogenase large subunit K14126 mvhA; F420-non-reducing hydrogenase large subunit [EC:1.12.99.- 1.8.98.5] D Mefer_0239 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 mvhG; F420-non-reducing hydrogenase small subunit [EC:1.12.99.- 1.8.98.5] D Mefer_0312 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Mefer_0884 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Mefer_0883 thiamine pyrophosphate protein domain protein TPP-binding K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Mefer_0886 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Mefer_0885 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Mefer_0788 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Mefer_1510 phosphonopyruvate decarboxylase-related protein K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Mefer_0636 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Mefer_0829 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D Mefer_0102 Phosphosulfolactate synthase K08097 comA; phosphosulfolactate synthase [EC:4.4.1.19] D Mefer_0815 2-phosphosulfolactate phosphatase K05979 comB; 2-phosphosulfolactate phosphatase [EC:3.1.3.71] D Mefer_1396 (R)-2-hydroxyacid dehydrogenase K05884 comC; L-2-hydroxycarboxylate dehydrogenase (NAD+) [EC:1.1.1.337] D Mefer_0101 conserved hypothetical protein K06034 comD; sulfopyruvate decarboxylase subunit alpha [EC:4.1.1.79] D Mefer_0100 thiamine pyrophosphate protein domain protein TPP-binding K13039 comE; sulfopyruvate decarboxylase subunit beta [EC:4.1.1.79] D Mefer_1391 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147] D Mefer_0989 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit K11780 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [EC:4.3.1.32] D Mefer_1466 2-phospho-L-lactate guanylyltransferase CofC K14941 cofC; 2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase [EC:2.7.7.68 2.7.7.105] D Mefer_0031 LPPG domain protein containing protein K11212 cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28] D Mefer_1035 F420-dependent oxidoreductase K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34] D Mefer_1229 alpha-L-glutamate ligase, RimK family K14940 cofF; gamma-F420-2:alpha-L-glutamate ligase [EC:6.3.2.32] D Mefer_0710 isopropylmalate/citramalate/homocitrate synthase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-] D Mefer_1231 3-isopropylmalate dehydratase K16792 aksD; methanogen homoaconitase large subunit [EC:4.2.1.114] D Mefer_0048 3-isopropylmalate dehydratase, small subunit K16793 aksE; methanogen homoaconitase small subunit [EC:4.2.1.114] D Mefer_0957 isopropylmalate/isohomocitrate dehydrogenase K10978 aksF; methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-] D Mefer_1281 Pyridoxal-dependent decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] D Mefer_1180 protein of unknown function DUF201 K06914 mfnD; tyramine---L-glutamate ligase [EC:6.3.4.24] D Mefer_0778 protein of unknown function DUF556 K09733 mfnB; (5-formylfuran-3-yl)methyl phosphate synthase [EC:4.2.3.153] D Mefer_0615 aminotransferase class I and II K19793 mfnC; (5-formylfuran-3-yl)methyl phosphate transaminase [EC:2.6.1.108] D Mefer_0695 aspartate/glutamate/uridylate kinase K07144 mfnE; 5-(aminomethyl)-3-furanmethanol phosphate kinase [EC:2.7.4.31] D Mefer_0932 H4MPT-linked C1 transfer pathway protein K07072 mfnF; (4-(4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl)furan-2-yl)methanamine synthase [EC:2.5.1.131] C 00910 Nitrogen metabolism [PATH:mfe00910] D Mefer_1138 nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH D Mefer_1043 hybrid cluster protein K05601 hcp; hydroxylamine reductase [EC:1.7.99.1] D Mefer_0175 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Mefer_0652 carbonic anhydrase K01673 cynT; carbonic anhydrase [EC:4.2.1.1] C 00920 Sulfur metabolism [PATH:mfe00920] D Mefer_0146 ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic components K15553 ssuA; sulfonate transport system substrate-binding protein D Mefer_1306 binding-protein-dependent transport systems inner membrane component K15554 ssuC; sulfonate transport system permease protein D Mefer_1307 ABC transporter related K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D Mefer_0417 phosphoadenosine phosphosulfate reductase K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis C 00062 Fatty acid elongation C 00071 Fatty acid degradation [PATH:mfe00071] D Mefer_1483 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism C 00564 Glycerophospholipid metabolism [PATH:mfe00564] D Mefer_1182 phosphatidylserine decarboxylase related protein K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65] D Mefer_1077 3-dehydroquinate synthase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261] D Mefer_0372 geranylgeranylglyceryl phosphate synthase K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41] D Mefer_0645 UbiA prenyltransferase K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42] D Mefer_0314 protein of unknown function DUF46 K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67] D Mefer_0273 CDP-diacylglycerol/serine O-phosphatidyltransferase K19665 pssA; archaetidylserine synthase [EC:2.7.8.38] D Mefer_0023 geranylgeranyl reductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11] D Mefer_0586 geranylgeranyl reductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:mfe00230] D Mefer_1352 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Mefer_0475 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D Mefer_0864 phosphoribosylamine/glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D Mefer_0364 phosphoribosylglycinamide formyltransferase 2 K08289 purT; phosphoribosylglycinamide formyltransferase 2 [EC:6.3.1.21] D Mefer_0027 phosphoribosylformylglycinamidine synthase II K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3] D Mefer_0828 phosphoribosylformylglycinamidine synthase, purS K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3] D Mefer_0265 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Mefer_0476 phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D Mefer_0212 phosphoribosylaminoimidazole carboxylase, catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D Mefer_0827 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D Mefer_0765 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D Mefer_0308 IMP biosynthesis enzyme PurP domain protein K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23] D Mefer_1424 IMP cyclohydrolase K11176 purO; IMP cyclohydrolase [EC:3.5.4.10] D Mefer_0731 phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Mefer_0802 stationary-phase survival protein SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Mefer_1313 PfkB domain protein K22026 K22026; nucleoside kinase [EC:2.7.1.73 2.7.1.213 2.7.1.-] D Mefer_1507 inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D Mefer_0026 Nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Mefer_0366 protein of unknown function DUF84 K01529 yjjX; inosine/xanthosine triphosphatase [EC:3.6.1.73] D Mefer_0455 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D Mefer_0289 GMP synthase, large subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Mefer_1522 GMP synthase, small subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Mefer_0922 anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D Mefer_0438 adenylyl cyclase CyaB K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1] D Mefer_0803 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D Mefer_1403 AMP phosphorylase K18931 deoA; AMP phosphorylase [EC:2.4.2.57] D Mefer_0127 adenine deaminase K01486 ade; adenine deaminase [EC:3.5.4.2] D Mefer_0672 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Mefer_0111 Adenylate kinase K18532 AK6; adenylate kinase [EC:2.7.4.3] C 00240 Pyrimidine metabolism [PATH:mfe00240] D Mefer_0005 MGS domain protein K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Mefer_0006 Carbamoyl-phosphate synthase L chain ATP-binding K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Mefer_0635 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D Mefer_0759 aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D Mefer_0081 aspartate carbamoyltransferase, regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D Mefer_1151 dihydroorotase, multifunctional complex type K01465 URA4; dihydroorotase [EC:3.5.2.3] D Mefer_0665 dihydroorotate dehydrogenase family protein K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14] D Mefer_1011 oxidoreductase FAD/NAD(P)-binding domain protein K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit D Mefer_0307 orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D Mefer_0105 orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D Mefer_0034 uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D Mefer_0026 Nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Mefer_0152 CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2] D Mefer_0948 cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D Mefer_0802 stationary-phase survival protein SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Mefer_1313 PfkB domain protein K22026 K22026; nucleoside kinase [EC:2.7.1.73 2.7.1.213 2.7.1.-] D Mefer_1403 AMP phosphorylase K18931 deoA; AMP phosphorylase [EC:2.4.2.57] D Mefer_0922 anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D Mefer_1292 deoxycytidine triphosphate deaminase K09887 dcd; dCTP deaminase (dUMP-forming) [EC:3.5.4.30] D Mefer_0667 thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D Mefer_0781 deoxyUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D Mefer_0421 thymidylate synthase, methanogen type K00560 thyA; thymidylate synthase [EC:2.1.1.45] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:mfe00250] D Mefer_0825 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Mefer_0302 asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D Mefer_1293 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Mefer_1000 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Mefer_0803 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D Mefer_0765 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D Mefer_0759 aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D Mefer_0081 aspartate carbamoyltransferase, regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D Mefer_0175 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Mefer_0005 MGS domain protein K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Mefer_0006 Carbamoyl-phosphate synthase L chain ATP-binding K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Mefer_0635 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D Mefer_0265 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Mefer_0113 glucosamine/fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Mefer_0475 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:mfe00260] D Mefer_1354 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Mefer_0474 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Mefer_0316 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Mefer_0018 homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39] D Mefer_0040 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D Mefer_0958 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Mefer_1510 phosphonopyruvate decarboxylase-related protein K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Mefer_0636 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Mefer_0829 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D Mefer_0246 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Mefer_1260 tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D Mefer_1259 tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] C 00270 Cysteine and methionine metabolism [PATH:mfe00270] D Mefer_1219 Methionine synthase vitamin-B12 independent K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D Mefer_0283 Methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D Mefer_1278 S-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50] D Mefer_1279 spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] D Mefer_1477 amidohydrolase K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28] D Mefer_0904 methylthioadenosine phosphorylase K19696 mtiP; 5'-methylthioinosine phosphorylase [EC:2.4.2.44] D Mefer_0700 translation initiation factor, aIF-2BI family K08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23] D Mefer_0804 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mefer_1100 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mefer_0890 adenosylhomocysteinase K01566 E3.13.1.9; S-inosyl-L-homocysteine hydrolase [EC:3.13.1.9] D Mefer_1354 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Mefer_0474 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Mefer_0316 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Mefer_0355 protein of unknown function DUF39 K23975 E2.8.1.16; L-aspartate semialdehyde sulfurtransferase [EC:2.8.1.16] D Mefer_0356 NIL domain protein K23976 K23976; L-aspartate semialdehyde sulfurtransferase ferredoxin D Mefer_0910 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Mefer_0825 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Mefer_1194 protein of unknown function DUF1063 K20021 E4.4.1.28; L-cysteine desulfidase [EC:4.4.1.28] D Mefer_0722 Malate dehydrogenase (NADP(+)) K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Mefer_0636 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] C 00280 Valine, leucine and isoleucine degradation [PATH:mfe00280] D Mefer_0910 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Mefer_0246 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Mefer_1483 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Mefer_1482 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:mfe00290] D Mefer_0142 isopropylmalate/citramalate/homocitrate synthase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21] D Mefer_0713 homoaconitate hydratase family protein K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Mefer_0041 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Mefer_1072 isopropylmalate/isohomocitrate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D Mefer_0954 thiamine pyrophosphate protein domain protein TPP-binding K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Mefer_0138 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Mefer_0195 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Mefer_1479 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D Mefer_0042 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D Mefer_0910 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Mefer_0244 isopropylmalate/citramalate/homocitrate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00300 Lysine biosynthesis [PATH:mfe00300] D Mefer_0316 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Mefer_1354 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Mefer_0474 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Mefer_0435 dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D Mefer_1297 dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] D Mefer_1071 acetylornithine and succinylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Mefer_0696 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D Mefer_0299 diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D Mefer_0889 aminotransferase class I and II K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] D Mefer_0773 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D Mefer_0710 isopropylmalate/citramalate/homocitrate synthase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-] D Mefer_1231 3-isopropylmalate dehydratase K16792 aksD; methanogen homoaconitase large subunit [EC:4.2.1.114] D Mefer_0048 3-isopropylmalate dehydratase, small subunit K16793 aksE; methanogen homoaconitase small subunit [EC:4.2.1.114] D Mefer_0957 isopropylmalate/isohomocitrate dehydrogenase K10978 aksF; methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-] C 00310 Lysine degradation [PATH:mfe00310] D Mefer_0246 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Mefer_1483 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Mefer_0245 lysine 2,3-aminomutase YodO family protein K01843 kamA; lysine 2,3-aminomutase [EC:5.4.3.2] C 00220 Arginine biosynthesis [PATH:mfe00220] D Mefer_1471 ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D Mefer_1293 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Mefer_1000 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Mefer_0265 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Mefer_0175 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Mefer_0825 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Mefer_0362 arginine biosynthesis bifunctional protein ArgJ K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1] D Mefer_0413 acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8] D Mefer_0772 N-acetyl-gamma-glutamyl-phosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] D Mefer_1071 acetylornithine and succinylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Mefer_0895 peptidase dimerization domain protein K01438 argE; acetylornithine deacetylase [EC:3.5.1.16] C 00330 Arginine and proline metabolism [PATH:mfe00330] D Mefer_1277 arginine decarboxylase, pyruvoyl-dependent K02626 pdaD; arginine decarboxylase [EC:4.1.1.19] D Mefer_0143 agmatinase K01480 speB; agmatinase [EC:3.5.3.11] D Mefer_1279 spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] D Mefer_1278 S-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50] D Mefer_0825 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] C 00340 Histidine metabolism [PATH:mfe00340] D Mefer_1104 ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17] D Mefer_0558 phosphoribosyl-ATP diphosphatase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31] D Mefer_1392 Phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19] D Mefer_1087 hisA/hisF family protein K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D Mefer_1533 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D Mefer_0707 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10] D Mefer_1308 imidazoleglycerol phosphate synthase, cyclase subunit K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10] D Mefer_1092 Imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19] D Mefer_0844 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Mefer_1145 histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23] C 00350 Tyrosine metabolism [PATH:mfe00350] D Mefer_0825 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Mefer_0844 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Mefer_1281 Pyridoxal-dependent decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] C 00360 Phenylalanine metabolism [PATH:mfe00360] D Mefer_0825 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Mefer_0844 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00380 Tryptophan metabolism [PATH:mfe00380] D Mefer_0246 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Mefer_1483 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:mfe00400] D Mefer_0658 Fructose-bisphosphate aldolase K16305 K16305; fructose-bisphosphate aldolase / 6-deoxy-5-ketofructose 1-phosphate synthase [EC:4.1.2.13 2.2.1.11] D Mefer_1187 predicted phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D Mefer_0373 3-dehydroquinate synthase K11646 K11646; 3-dehydroquinate synthase II [EC:1.4.1.24] D Mefer_1020 3-dehydroquinate dehydratase, type I K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10] D Mefer_1347 shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] D Mefer_0186 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71] D Mefer_0711 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D Mefer_0151 chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D Mefer_0507 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Mefer_0441 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D Mefer_0445 anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18] D Mefer_1195 Phosphoribosylanthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24] D Mefer_0068 Indole-3-glycerol-phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48] D Mefer_1260 tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D Mefer_1259 tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D Mefer_0433 chorismate mutase K04093 pheA1; chorismate mutase [EC:5.4.99.5] D Mefer_0217 Prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D Mefer_0247 prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51] D Mefer_0825 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Mefer_0844 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism [PATH:mfe00410] D Mefer_1281 Pyridoxal-dependent decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] D Mefer_0471 Protein of unknown function DUF137 K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] C 00430 Taurine and hypotaurine metabolism C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:mfe00450] D Mefer_1219 Methionine synthase vitamin-B12 independent K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D Mefer_1537 thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D Mefer_0826 selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3] D Mefer_1539 L-seryl-tRNA(Sec) kinase K10837 PSTK; O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164] D Mefer_0198 pyridoxal phosphate enzyme K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1] D Mefer_0221 O-phosphoseryl-tRNA(Sec) selenium transferase K03341 SEPSECS; O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase [EC:2.9.1.2] D Mefer_0039 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism D Mefer_0958 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism [PATH:mfe00470] D Mefer_0265 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Mefer_0299 diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D Mefer_0773 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] C 00480 Glutathione metabolism [PATH:mfe00480] D Mefer_1279 spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis C 00541 O-Antigen nucleotide sugar biosynthesis C 00550 Peptidoglycan biosynthesis C 00552 Teichoic acid biosynthesis C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:mfe00730] D Mefer_0126 thiamine biosynthesis protein ThiC K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17] D Mefer_0443 Phosphomethylpyrimidine kinase K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3] D Mefer_0763 thiamine biosynthesis/tRNA modification protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D Mefer_1385 thiazole biosynthesis enzyme K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] D Mefer_1244 thiamine-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16] D Mefer_0672 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism [PATH:mfe00740] D Mefer_0498 GTP cyclohydrolase IIa K08096 gch3; GTP cyclohydrolase IIa [EC:3.5.4.29] D Mefer_0820 Creatininase K14653 arfB; 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase [EC:3.5.1.102] D Mefer_0630 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302] D Mefer_0603 3,4-dihydroxy-2-butanone 4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12] D Mefer_0557 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D Mefer_0231 riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9] D Mefer_0604 CTP-dependent riboflavin kinase K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161] D Mefer_0147 cytidyltransferase-related domain protein K14656 ribL; FAD synthetase [EC:2.7.7.2] D Mefer_0353 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] C 00750 Vitamin B6 metabolism [PATH:mfe00750] D Mefer_0040 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D Mefer_0621 pyridoxine biosynthesis protein K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6] D Mefer_0727 SNO glutamine amidotransferase K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6] C 00760 Nicotinate and nicotinamide metabolism [PATH:mfe00760] D Mefer_0063 Aspartate dehydrogenase K06989 nadX; aspartate dehydrogenase [EC:1.4.1.21] D Mefer_1312 quinolinate synthetase complex, A subunit K03517 nadA; quinolinate synthase [EC:2.5.1.72] D Mefer_0719 nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D Mefer_0802 stationary-phase survival protein SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Mefer_0787 nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1] D Mefer_0664 NAD+ synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5] D Mefer_0065 ATP-NAD/AcoX kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] C 00770 Pantothenate and CoA biosynthesis [PATH:mfe00770] D Mefer_0954 thiamine pyrophosphate protein domain protein TPP-binding K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Mefer_0138 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Mefer_0195 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Mefer_1479 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D Mefer_0042 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D Mefer_0856 GHMP kinase K06982 pok; pantoate kinase [EC:2.7.1.169] D Mefer_0471 Protein of unknown function DUF137 K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] D Mefer_0061 phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] D Mefer_0119 cytidyltransferase-related domain protein K02201 E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D Mefer_0874 Protein of unknown function DUF359 K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237] D Mefer_0910 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Mefer_1281 Pyridoxal-dependent decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] C 00780 Biotin metabolism [PATH:mfe00780] D Mefer_0991 Radical SAM domain protein K01012 bioB; biotin synthase [EC:2.8.1.6] D Mefer_1526 biotin synthase K01012 bioB; biotin synthase [EC:2.8.1.6] D Mefer_1504 biotin/acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism [PATH:mfe00785] D Mefer_0246 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00790 Folate biosynthesis [PATH:mfe00790] D Mefer_0047 6-pyruvoyl tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D Mefer_0262 Radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D Mefer_0176 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D Mefer_1030 protein of unknown function DUF198 K17488 mptA; GTP cyclohydrolase IV [EC:3.5.4.39] D Mefer_0929 metal dependent phosphohydrolase K17487 mptB; 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase [EC:3.1.4.56] D Mefer_1311 Protein of unknown function DUF381 K09739 mptD; dihydroneopterin aldolase [EC:4.1.2.25] D Mefer_1326 protein of unknown function DUF115 K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D Mefer_1394 beta-ribofuranosylaminobenzene 5'-phosphate synthase family K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54] D Mefer_1190 beta-lactamase domain protein K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105] D Mefer_0472 archaeoflavoprotein, MJ0208 family K18853 dmrX; dihydromethanopterin reductase (acceptor) [EC:1.5.99.15] D Mefer_0208 alpha-L-glutamate ligase, RimK family K15740 mptN; tetrahydromethanopterin:alpha-L-glutamate ligase [EC:6.3.2.33] D Mefer_0915 molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D Mefer_1148 molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D Mefer_1075 molybdopterin biosynthesis MoaE protein K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12] D Mefer_0189 molybdenum cofactor synthesis domain protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D Mefer_1404 molybdenum cofactor synthesis domain protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] D Mefer_1467 molybdenum cofactor synthesis domain protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] D Mefer_0960 Molybdopterin-guanine dinucleotide biosynthesis protein A-like protein K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77] C 00670 One carbon pool by folate [PATH:mfe00670] D Mefer_0958 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Mefer_0421 thymidylate synthase, methanogen type K00560 thyA; thymidylate synthase [EC:2.1.1.45] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:mfe00860] D Mefer_0007 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Mefer_0496 glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70] D Mefer_1387 glutamate-1-semialdehyde-2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D Mefer_0258 Porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D Mefer_0770 porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61] D Mefer_1494 Uroporphyrinogen III synthase HEM4 K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] D Mefer_0849 uroporphyrin-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107] D Mefer_0978 siroheme synthase K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76] D Mefer_0855 cobalamin (vitamin B12) biosynthesis CbiX protein K22011 cfbA; sirohydrochlorin cobalto/nickelchelatase [EC:4.99.1.3 4.99.1.11] D Mefer_1034 precorrin-2 C20-methyltransferase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151] D Mefer_1178 precorrin-3B C17-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272] D Mefer_1523 precorrin-4 C11-methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271] D Mefer_0812 cobalamin (vitamin B12) biosynthesis CbiG protein K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12] D Mefer_0798 precorrin-6x reductase K05895 cobK-cbiJ; precorrin-6A/cobalt-precorrin-6A reductase [EC:1.3.1.54 1.3.1.106] D Mefer_1249 cobalamin biosynthesis protein CbiD K02188 cbiD; cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195] D Mefer_0878 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196] D Mefer_0587 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289] D Mefer_0764 Precorrin-8X methylmutase CbiC/CobH K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60] D Mefer_0145 cobyrinic acid a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11] D Mefer_1199 Cobaltochelatase., Magnesium chelatase K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2] D Mefer_0187 Magnesium chelatase K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2] D Mefer_1585 cobyric acid synthase CobQ K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10] D Mefer_1420 cobalamin biosynthesis protein CobD K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10] D Mefer_0301 GTP:adenosylcobinamide-phosphate guanylyltransferase-like protein K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62] D Mefer_0184 cobalamin 5'-phosphate synthase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26] D Mefer_1398 methanogenesis marker 13 metalloprotein K21611 cfbD; Ni-sirohydrochlorin a,c-diamide reductive cyclase subunit CfbD [EC:6.3.3.7] D Mefer_0369 Mur ligase middle domain protein K21612 cfbE; coenzyme F430 synthetase [EC:6.4.1.9] D Mefer_1197 Magnesium chelatase K03405 chlI; magnesium chelatase subunit I [EC:6.6.1.1] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis D Mefer_0353 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:mfe00900] D Mefer_1483 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Mefer_1482 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D Mefer_1084 3-hydroxy-3-methylglutaryl Coenzyme A reductase K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34] D Mefer_1345 mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36] D Mefer_0425 aspartate/glutamate/uridylate kinase K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26] D Mefer_1421 protein of unknown function DUF521 K25517 acnX1; phosphomecalonate degydratase large subunit [EC:4.2.1.182] D Mefer_0080 protein of unknown function DUF126 K09128 acnX2; phosphomecalonate degydratase small subunit [EC:4.2.1.182] D Mefer_0287 UbiD family decarboxylase K25518 E4.1.1.126; anhydromevalonate phosphate decarboxylase [EC:4.1.1.126] D Mefer_0353 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] D Mefer_1122 isopentenyl-diphosphate delta-isomerase, type 2 K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2] D Mefer_1120 Polyprenyl synthetase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D Mefer_0013 undecaprenyl diphosphate synthase K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D Mefer_0617 Transketolase domain protein K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D Mefer_0619 Transketolase central region K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis D Mefer_0780 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis C 00332 Carbapenem biosynthesis C 00261 Monobactam biosynthesis [PATH:mfe00261] D Mefer_1354 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Mefer_0474 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Mefer_0435 dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D Mefer_1297 dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:mfe00521] D Mefer_0344 Inositol-phosphate phosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Mefer_0780 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] C 00524 Neomycin, kanamycin and gentamicin biosynthesis C 00525 Acarbose and validamycin biosynthesis D Mefer_0780 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] C 00401 Novobiocin biosynthesis [PATH:mfe00401] D Mefer_0217 Prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D Mefer_0825 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Mefer_0844 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D Mefer_0507 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Mefer_0441 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics C 00999 Biosynthesis of various plant secondary metabolites [PATH:mfe00999] D Mefer_0283 Methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D Mefer_1347 shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation [PATH:mfe00362] D Mefer_0556 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D Mefer_1483 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00627 Aminobenzoate degradation [PATH:mfe00627] D Mefer_1613 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D Mefer_0353 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation D Mefer_1138 nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH C 00361 Chlorocyclohexane and chlorobenzene degradation C 00623 Toluene degradation C 00622 Xylene degradation D Mefer_0556 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00633 Nitrotoluene degradation [PATH:mfe00633] D Mefer_0881 4Fe-4S ferredoxin iron-sulfur binding domain protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D Mefer_0882 4Fe-4S ferredoxin iron-sulfur binding domain protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D Mefer_0884 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Mefer_0883 thiamine pyrophosphate protein domain protein TPP-binding K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Mefer_0886 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Mefer_0885 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] C 00642 Ethylbenzene degradation C 00643 Styrene degradation C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation D Mefer_0556 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00626 Naphthalene degradation C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:mfe03020] D Mefer_1263 DNA-directed RNA polymerase subunit B K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6] D Mefer_1262 RNA polymerase beta subunit K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6] D Mefer_1264 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6] D Mefer_1265 DNA-directed RNA polymerase, subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6] D Mefer_0487 RNA polymerase insert K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6] D Mefer_0702 RNA polymerase dimerization K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6] D Mefer_0872 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6] D Mefer_0570 RNA polymerase Rpb4 K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6] D Mefer_1261 RNA polymerase Rpb5 K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6] D Mefer_0482 RNA polymerase Rpb6 K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6] D Mefer_0483 RNA polymerase, N/8 Kd subunit K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6] D Mefer_1379 RNA polymerase Rbp10 K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6] C 03022 Basal transcription factors [PATH:mfe03022] D Mefer_1023 Transcription factor TFIIB cyclin-related K03124 TFIIB; transcription initiation factor TFIIB D Mefer_0706 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D Mefer_1028 Transcription factor TFIIE, alpha subunit K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:mfe03010] D Mefer_1409 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D Mefer_0691 ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D Mefer_0489 ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D Mefer_0676 ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D Mefer_1269 ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D Mefer_0681 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D Mefer_0484 ribosomal protein S9P K02996 RP-S9; small subunit ribosomal protein S9 D Mefer_1272 ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D Mefer_0488 ribosomal protein S11P K02948 RP-S11; small subunit ribosomal protein S11 D Mefer_1268 ribosomal protein S23 (S12) K02950 RP-S12; small subunit ribosomal protein S12 D Mefer_0490 ribosomal protein S13P K02952 RP-S13; small subunit ribosomal protein S13 D Mefer_0682 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D Mefer_1234 Ribosomal S13S15 domain protein K02956 RP-S15; small subunit ribosomal protein S15 D Mefer_0687 ribosomal protein S17P K02961 RP-S17; small subunit ribosomal protein S17 D Mefer_0736 ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D Mefer_1411 ribosomal protein S3Ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae D Mefer_0684 Ribosomal protein S4E, central domain protein K02987 RP-S4e; small subunit ribosomal protein S4e D Mefer_0036 Ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e D Mefer_0627 ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e D Mefer_0434 40S ribosomal protein S17-A; K02962 small subunit ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e D Mefer_0609 Ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e D Mefer_0875 Ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e D Mefer_0429 Ribosomal protein S27E K02978 RP-S27e; small subunit ribosomal protein S27e D Mefer_0876 Ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D Mefer_1102 Ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e D Mefer_0703 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D Mefer_0737 ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D Mefer_0740 ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D Mefer_0683 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Mefer_0680 ribosomal protein L6P K02933 RP-L6; large subunit ribosomal protein L6 D Mefer_0704 ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D Mefer_1446 ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Mefer_0705 ribosomal protein 60S K02869 RP-L12; large subunit ribosomal protein L12 D Mefer_0485 ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D Mefer_0686 50S ribosomal protein L14P K02874 RP-L14; large subunit ribosomal protein L14 D Mefer_0674 ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D Mefer_0677 ribosomal protein L18P/L5E K02881 RP-L18; large subunit ribosomal protein L18 D Mefer_0692 ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D Mefer_0738 ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D Mefer_0685 ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D Mefer_0690 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Mefer_0675 ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30 D Mefer_0739 50S ribosomal protein L4P K02930 RP-L4e; large subunit ribosomal protein L4e D Mefer_1103 ribosomal protein L7Ae/L30e/S12e/Gadd45 K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D Mefer_0789 ribosomal protein L10.e K02866 RP-L10e; large subunit ribosomal protein L10e D Mefer_0949 conserved hypothetical protein K02875 RP-L14e; large subunit ribosomal protein L14e D Mefer_1408 Ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e D Mefer_0486 ribosomal protein L15 K02883 RP-L18e; large subunit ribosomal protein L18e D Mefer_0678 Ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e D Mefer_0571 Ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e D Mefer_1101 Ribosomal protein L24E K02896 RP-L24e; large subunit ribosomal protein L24e D Mefer_1266 ribosomal protein L7Ae/L30e/S12e/Gadd45 K02908 RP-L30e; large subunit ribosomal protein L30e D Mefer_0309 Ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e D Mefer_0679 Ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e D Mefer_0947 Ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e D Mefer_0384 Ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e D Mefer_1378 ribosomal protein L37a K02921 RP-L37Ae; large subunit ribosomal protein L37Ae D Mefer_0612 Ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e D Mefer_1082 hypothetical protein K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D Mefer_0430 Ribosomal protein L44E K02929 RP-L44e; large subunit ribosomal protein L44e D Mefer_1382 Ribosomal LX protein K02944 RP-LX; large subunit ribosomal protein LX D Mefer_R0001 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Mefer_R0033 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Mefer_R0003 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Mefer_R0031 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Mefer_R0023 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Mefer_R0030 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:mfe00970] D Mefer_R0009 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Mefer_R0002 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Mefer_R0032 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Mefer_R0014 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Mefer_R0018 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Mefer_R0026 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Mefer_R0038 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Mefer_R0024 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Mefer_R0013 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Mefer_R0028 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Mefer_R0025 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Mefer_R0036 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Mefer_R0005 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Mefer_R0004 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Mefer_R0034 tRNA-His K14226 tRNA-His; tRNA His D Mefer_R0016 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Mefer_R0010 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Mefer_R0035 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Mefer_R0006 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Mefer_R0022 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Mefer_R0037 tRNA-Met K14230 tRNA-Met; tRNA Met D Mefer_R0041 tRNA-Met K14230 tRNA-Met; tRNA Met D Mefer_R0007 tRNA-Met K14230 tRNA-Met; tRNA Met D Mefer_R0039 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Mefer_R0011 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Mefer_R0020 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Mefer_R0045 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Mefer_R0042 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Mefer_R0012 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Mefer_R0027 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Mefer_R0019 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Mefer_R0008 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Mefer_R0021 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Mefer_R0040 tRNA-Val K14237 tRNA-Val; tRNA Val D Mefer_R0043 tRNA-Val K14237 tRNA-Val; tRNA Val D Mefer_R0017 tRNA-Val K14237 tRNA-Val; tRNA Val D Mefer_R0015 tRNA-Sec K14238 tRNA-Sec; tRNA Sec D Mefer_0007 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Mefer_1389 glutamyl-tRNA(Gln) amidotransferase, A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D Mefer_0196 glutamyl-tRNA(Gln) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Mefer_0436 Asp/Glu amidotransferase, subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D Mefer_1251 glutamyl-tRNA(Gln) amidotransferase, subunit D K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7] D Mefer_1252 aspartyl-tRNA(Asn) amidotransferase, B subunit K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7] D Mefer_0805 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Mefer_1488 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D Mefer_0453 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Mefer_0144 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Mefer_0505 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Mefer_1539 L-seryl-tRNA(Sec) kinase K10837 PSTK; O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164] D Mefer_0221 O-phosphoseryl-tRNA(Sec) selenium transferase K03341 SEPSECS; O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase [EC:2.9.1.2] D Mefer_0198 pyridoxal phosphate enzyme K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1] D Mefer_0735 O-phosphoseryl-tRNA(Cys) synthetase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27] D Mefer_0975 Sep-tRNA K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73] D Mefer_0039 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Mefer_0911 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Mefer_1429 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Mefer_0836 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Mefer_0785 lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Mefer_0442 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Mefer_0381 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Mefer_1228 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Mefer_0725 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Mefer_1353 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Mefer_0880 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Mefer_0272 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:mfe03060] D Mefer_0673 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Mefer_0342 SecD/SecF/SecDF export membrane protein K03072 secD; preprotein translocase subunit SecD D Mefer_0028 SecD/SecF/SecDF export membrane protein K03074 secF; preprotein translocase subunit SecF D Mefer_0354 GTP-binding signal recognition particle SRP54 G-domain protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Mefer_R0044 ffs; SRP RNA; RNA component of signal recognitionparti cle K01983 ffs; SRP RNA D Mefer_0002 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Mefer_1448 protein translocase SEC61 complex, gamma subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D Mefer_1256 Ribonucleoprotein complex SRP, Srp19 component K03105 SRP19; signal recognition particle subunit SRP19 D Mefer_0813 arsenite-activated ATPase ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:mfe04122] D Mefer_1497 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D Mefer_1075 molybdopterin biosynthesis MoaE protein K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12] D Mefer_0915 molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D Mefer_1148 molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D Mefer_0189 molybdenum cofactor synthesis domain protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D Mefer_0763 thiamine biosynthesis/tRNA modification protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] C 03050 Proteasome [PATH:mfe03050] D Mefer_0150 26S proteasome subunit P45 family K03420 psmR; proteasome regulatory subunit D Mefer_1376 proteasome endopeptidase complex, alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D Mefer_0382 proteasome endopeptidase complex, beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1] C 03018 RNA degradation [PATH:mfe03018] D Mefer_0447 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Mefer_1401 DEAD/DEAH box helicase domain protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Mefer_1121 beta-lactamase domain protein K12574 rnj; ribonuclease J [EC:3.1.-.-] D Mefer_0181 Uncharacterized host factor I protein-like protein K03666 hfq; host factor-I protein B B 09124 Replication and repair C 03030 DNA replication [PATH:mfe03030] D Mefer_1106 TOPRIM domain protein K02316 dnaG; DNA primase [EC:2.7.7.101] D Mefer_1155 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Mefer_1468 DNA-directed DNA polymerase K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D Mefer_1088 DNA-directed DNA polymerase K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7] D Mefer_1319 DNA polymerase II, large subunit DP2 K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7] D Mefer_1152 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D Mefer_0847 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D Mefer_1579 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D Mefer_1610 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D Mefer_0931 DNA primase, small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102] D Mefer_1089 DNA primase, large subunit K18882 priL; DNA primase large subunit D Mefer_0749 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1 D Mefer_0432 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen D Mefer_1399 Replication factor C K04801 rfcS; replication factor C small subunit D Mefer_1474 AAA ATPase central domain protein K04800 rfcL; replication factor C large subunit D Mefer_1010 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D Mefer_0746 DNA ligase I, ATP-dependent Dnl1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03410 Base excision repair [PATH:mfe03410] D Mefer_0216 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D Mefer_0432 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen D Mefer_1010 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D Mefer_0746 DNA ligase I, ATP-dependent Dnl1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D Mefer_1161 Xylose isomerase domain protein TIM barrel K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D Mefer_0921 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Mefer_0851 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] C 03420 Nucleotide excision repair [PATH:mfe03420] D Mefer_0749 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1 D Mefer_0432 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen D Mefer_0746 DNA ligase I, ATP-dependent Dnl1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03430 Mismatch repair [PATH:mfe03430] D Mefer_0921 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Mefer_0851 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Mefer_0432 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen D Mefer_0749 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1 D Mefer_0746 DNA ligase I, ATP-dependent Dnl1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03440 Homologous recombination [PATH:mfe03440] D Mefer_0921 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Mefer_0851 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Mefer_0749 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1 C 03450 Non-homologous end-joining D Mefer_1010 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 D Mefer_0873 DNA-directed RNA polymerase subunit E, RpoE2 K15171 SUPT4H1; transcription elongation factor SPT4 D Mefer_1447 NusG antitermination factor K15172 SUPT5H; transcription elongation factor SPT5 C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus and Lyssavirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:mfe02010] D Mefer_0233 extracellular solute-binding protein family 1 K15495 wtpA; molybdate/tungstate transport system substrate-binding protein D Mefer_0016 binding-protein-dependent transport systems inner membrane component K15496 wtpB; molybdate/tungstate transport system permease protein D Mefer_0017 ABC transporter related K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6] D Mefer_0146 ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic components K15553 ssuA; sulfonate transport system substrate-binding protein D Mefer_1306 binding-protein-dependent transport systems inner membrane component K15554 ssuC; sulfonate transport system permease protein D Mefer_1307 ABC transporter related K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D Mefer_1160 molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 modA; molybdate transport system substrate-binding protein D Mefer_1159 NifC-like ABC-type porter K02018 modB; molybdate transport system permease protein D Mefer_1158 ABC transporter related K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D Mefer_0337 binding-protein-dependent transport systems inner membrane component K05846 opuBD; osmoprotectant transport system permease protein D Mefer_0905 phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D Mefer_0906 phosphate ABC transporter, inner membrane subunit PstC K02037 pstC; phosphate transport system permease protein D Mefer_0907 phosphate ABC transporter, inner membrane subunit PstA K02038 pstA; phosphate transport system permease protein D Mefer_0908 phosphate ABC transporter, ATPase subunit K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Mefer_0492 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein D Mefer_0491 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein D Mefer_0494 ABC transporter related K01995 livG; branched-chain amino acid transport system ATP-binding protein D Mefer_1342 cobalt transport protein K02009 cbiN; cobalt/nickel transport protein D Mefer_0541 hypothetical protein K02009 cbiN; cobalt/nickel transport protein D Mefer_0542 cobalamin (vitamin B12) biosynthesis CbiM protein K02007 cbiM; cobalt/nickel transport system permease protein D Mefer_1341 cobalamin biosynthesis protein CbiM K02007 cbiM; cobalt/nickel transport system permease protein D Mefer_1343 cobalt ABC transporter, inner membrane subunit CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein D Mefer_0540 cobalt ABC transporter, inner membrane subunit CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein D Mefer_1344 cobalt ABC transporter, ATPase subunit K02006 cbiO; cobalt/nickel transport system ATP-binding protein D Mefer_1527 BioY protein K03523 bioY; biotin transport system substrate-specific component C 02060 Phosphotransferase system (PTS) C 03070 Bacterial secretion system [PATH:mfe03070] D Mefer_0342 SecD/SecF/SecDF export membrane protein K03072 secD; preprotein translocase subunit SecD D Mefer_0028 SecD/SecF/SecDF export membrane protein K03074 secF; preprotein translocase subunit SecF D Mefer_0673 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Mefer_0002 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Mefer_0354 GTP-binding signal recognition particle SRP54 G-domain protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] B B 09132 Signal transduction C 02020 Two-component system [PATH:mfe02020] D Mefer_0905 phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D Mefer_0454 triphosphoribosyl-dephospho-CoA protein K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52] D Mefer_0607 nitrogen regulatory protein P-II K04751 glnB; nitrogen regulatory protein P-II 1 D Mefer_0175 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Mefer_1483 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Mefer_1107 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Mefer_1112 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Mefer_0753 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Mefer_0025 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Mefer_0642 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW D Mefer_0640 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Mefer_1110 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Mefer_0641 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Mefer_0902 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D Mefer_1294 nucleotide sugar dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:mfe02024] D Mefer_0181 Uncharacterized host factor I protein-like protein K03666 hfq; host factor-I protein D Mefer_0507 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Mefer_0441 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D Mefer_0492 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein D Mefer_0491 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein D Mefer_0494 ABC transporter related K01995 livG; branched-chain amino acid transport system ATP-binding protein D Mefer_0673 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Mefer_0002 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Mefer_0354 GTP-binding signal recognition particle SRP54 G-domain protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis [PATH:mfe02030] D Mefer_1112 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Mefer_0753 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Mefer_0025 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Mefer_0640 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Mefer_0642 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW D Mefer_1110 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Mefer_1108 CheC, inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC D Mefer_1109 CheC, inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC D Mefer_0641 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Mefer_0639 CheD, stimulates methylation of MCP protein K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44] D Mefer_1107 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] C 02040 Flagellar assembly C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D Mefer_0447 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance C 01502 Vancomycin resistance C 01503 Cationic antimicrobial peptide (CAMP) resistance B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:mfe01000] C 01001 Protein kinases [BR:mfe01001] D Mefer_0290 metalloendopeptidase, glycoprotease family K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1] D Mefer_0987 Non-specific serine/threonine protein kinase K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1] D Mefer_0509 Non-specific serine/threonine protein kinase K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1] D Mefer_0648 integral membrane sensor signal transduction histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3] D Mefer_0640 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] C 01009 Protein phosphatases and associated proteins [BR:mfe01009] D Mefer_0385 translation initiation factor aIF-2, beta subunit K03238 EIF2S2; translation initiation factor 2 subunit 2 D Mefer_0829 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] C 01002 Peptidases and inhibitors [BR:mfe01002] D Mefer_0927 Peptidase A24A domain protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D Mefer_1204 Peptidase A24B, FlaK domain protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D Mefer_0085 Peptidase A24B, FlaK domain protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D Mefer_1427 hydrogenase maturation protease HycI K08315 hycI; hydrogenase 3 maturation protease [EC:3.4.23.51] D Mefer_0289 GMP synthase, large subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Mefer_1522 GMP synthase, small subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Mefer_0475 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D Mefer_0113 glucosamine/fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Mefer_0302 asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D Mefer_1412 intracellular protease, PfpI family K05520 yhbO; deglycase [EC:3.5.1.124] D Mefer_0696 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D Mefer_1520 methionine aminopeptidase, type II K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D Mefer_1172 peptidase M24 K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9] D Mefer_0977 peptidase M48 Ste24p K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D Mefer_0117 peptidase S16, Lon-like protease K04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53] D Mefer_0566 signal peptide peptidase SppA, 36K type K04773 sppA; protease IV [EC:3.4.21.-] D Mefer_0220 Rhomboid family protein K07059 K07059; rhomboid family protein D Mefer_1376 proteasome endopeptidase complex, alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D Mefer_0382 proteasome endopeptidase complex, beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D Mefer_0392 peptidase U32 K08303 prtC; U32 family peptidase [EC:3.4.-.-] D Mefer_0448 peptidase U62 modulator of DNA gyrase K03592 pmbA; PmbA protein D Mefer_1492 peptidase U62 modulator of DNA gyrase K03568 tldD; TldD protein C 01003 Glycosyltransferases [BR:mfe01003] D Mefer_0304 Glycosyl transferase, family 4, conserved region K01001 ALG7; UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase [EC:2.7.8.15] D Mefer_0585 glycosyl transferase family 2 K21304 aglK; UDP-N-acetylglucosamine---dolichyl-phosphate N-acetylglucosaminyltransferase [EC:2.4.1.153] D Mefer_0590 Oligosaccharyl transferase STT3 subunit K21306 aglB; dolichyl-phosphooligosaccharide-protein glycotransferase [EC:2.4.99.21] D Mefer_0790 glycosyl transferase family 2 K00721 DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83] D Mefer_1515 Starch synthase K00703 glgA; starch synthase [EC:2.4.1.21] C 01005 Lipopolysaccharide biosynthesis proteins [BR:mfe01005] D Mefer_0532 rfaE bifunctional protein K21345 rfaE2; D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase [EC:2.7.7.70] D Mefer_0512 glycosyl transferase family 9 K02843 waaF; lipopolysaccharide heptosyltransferase II [EC:2.4.99.24] D Mefer_0513 glycosyl transferase family 9 K02843 waaF; lipopolysaccharide heptosyltransferase II [EC:2.4.99.24] D Mefer_0516 glycosyl transferase family 9 K02849 waaQ; lipopolysaccharide heptosyltransferase III [EC:2.4.99.25] D Mefer_0533 phosphoheptose isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28] D Mefer_0530 histidinol-phosphate phosphatase family protein K03273 gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83] D Mefer_0514 ADP-L-glycero-D-manno-heptose-6-epimerase K03274 gmhD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20] C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:mfe01011] C 01004 Lipid biosynthesis proteins [BR:mfe01004] D Mefer_0312 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Mefer_1374 acetyl coenzyme A synthetase (ADP forming), alpha domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:mfe01006] D Mefer_1120 Polyprenyl synthetase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] C 01007 Amino acid related enzymes [BR:mfe01007] D Mefer_0785 lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Mefer_0007 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Mefer_0880 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Mefer_0272 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Mefer_0442 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Mefer_0039 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Mefer_0836 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Mefer_0911 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Mefer_1429 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Mefer_1488 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D Mefer_1228 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Mefer_0453 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Mefer_0505 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Mefer_0381 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Mefer_0144 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Mefer_0805 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Mefer_0735 O-phosphoseryl-tRNA(Cys) synthetase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27] D Mefer_0725 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Mefer_1353 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Mefer_0825 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Mefer_0889 aminotransferase class I and II K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] D Mefer_0844 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Mefer_1071 acetylornithine and succinylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Mefer_1387 glutamate-1-semialdehyde-2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D Mefer_0910 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:mfe03000] D Mefer_0749 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1 D Mefer_0804 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mefer_1100 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mefer_0706 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D Mefer_0559 transcriptional regulator, LysR family K21900 cysL; LysR family transcriptional regulator, transcriptional activator of the cysJI operon D Mefer_1069 transcriptional regulator, AsnC family K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA D Mefer_0769 iron (metal) dependent repressor, DtxR family K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D Mefer_1504 biotin/acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D Mefer_0197 Protein of unknown function DUF128 K09720 nrpRI; HTH-type transcriptional regulator, global nitrogen regulator NrpRI D Mefer_0554 transcriptional regulator, TrmB K22109 gbsR; HTH-type transcriptional regulator, glycine betaine synthesis regulator D Mefer_0743 DNA binding protein, Tfx family K09714 tfx; HTH-type transcriptional regulator, fmd operon transcriptional regulator D Mefer_0263 phosphoribosyltransferase K26599 gfcR; HTH-type transcriptional regulator, activator of D-glucose/D-fructose catabolism D Mefer_1431 transcriptional regulator, ArsR family K07725 csa3; CRISPR-associated protein Csa3 D Mefer_0160 transcriptional regulator, XRE family K07728 K07728; putative transcriptional regulator D Mefer_1128 transcriptional regulator, XRE family K07729 K07729; putative transcriptional regulator D Mefer_0801 transcriptional regulator, MarR family K07730 K07730; putative transcriptional regulator D Mefer_1481 transcriptional regulator, XRE family K07731 K07731; putative transcriptional regulator D Mefer_0407 transcriptional regulator NikR, CopG family K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator D Mefer_1044 putative transcriptional regulator, CopG family K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator D Mefer_0795 transcriptional regulator NikR, CopG family K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator C 03021 Transcription machinery [BR:mfe03021] D Mefer_1023 Transcription factor TFIIB cyclin-related K03124 TFIIB; transcription initiation factor TFIIB D Mefer_0706 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D Mefer_1028 Transcription factor TFIIE, alpha subunit K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha D Mefer_0873 DNA-directed RNA polymerase subunit E, RpoE2 K15171 SUPT4H1; transcription elongation factor SPT4 D Mefer_1447 NusG antitermination factor K15172 SUPT5H; transcription elongation factor SPT5 D Mefer_1267 NusA family KH domain protein K02600 nusA; transcription termination/antitermination protein NusA D Mefer_1264 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6] D Mefer_1265 DNA-directed RNA polymerase, subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6] D Mefer_1263 DNA-directed RNA polymerase subunit B K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6] D Mefer_1262 RNA polymerase beta subunit K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6] D Mefer_0487 RNA polymerase insert K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6] D Mefer_0872 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6] D Mefer_0570 RNA polymerase Rpb4 K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6] D Mefer_1261 RNA polymerase Rpb5 K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6] D Mefer_1402 hypothetical protein K03054 rpoI; DNA-directed RNA polymerase subunit I [EC:2.7.7.6] D Mefer_0482 RNA polymerase Rpb6 K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6] D Mefer_0702 RNA polymerase dimerization K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6] D Mefer_0483 RNA polymerase, N/8 Kd subunit K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6] D Mefer_1379 RNA polymerase Rbp10 K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6] D Mefer_0808 transcription termination factor Tfs K03057 tfs; transcription factor S C 03019 Messenger RNA biogenesis [BR:mfe03019] D Mefer_0873 DNA-directed RNA polymerase subunit E, RpoE2 K15171 SUPT4H1; transcription elongation factor SPT4 D Mefer_1447 NusG antitermination factor K15172 SUPT5H; transcription elongation factor SPT5 D Mefer_0752 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase D Mefer_0742 translation factor pelota K06965 PELO; protein pelota D Mefer_0919 eRF1 domain 2 protein K03265 ETF1; peptide chain release factor subunit 1 D Mefer_1271 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha D Mefer_1121 beta-lactamase domain protein K12574 rnj; ribonuclease J [EC:3.1.-.-] D Mefer_1401 DEAD/DEAH box helicase domain protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Mefer_0447 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Mefer_0181 Uncharacterized host factor I protein-like protein K03666 hfq; host factor-I protein D Mefer_0598 DEAD/DEAH box helicase domain protein K03725 K03725; putative ATP-dependent RNA helicase [EC:3.6.4.-] C 03041 Spliceosome C 03011 Ribosome [BR:mfe03011] D Mefer_1411 ribosomal protein S3Ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae D Mefer_0684 Ribosomal protein S4E, central domain protein K02987 RP-S4e; small subunit ribosomal protein S4e D Mefer_0036 Ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e D Mefer_0627 ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e D Mefer_0434 40S ribosomal protein S17-A; K02962 small subunit ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e D Mefer_0609 Ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e D Mefer_0875 Ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e D Mefer_0429 Ribosomal protein S27E K02978 RP-S27e; small subunit ribosomal protein S27e D Mefer_0876 Ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D Mefer_1102 Ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e D Mefer_0739 50S ribosomal protein L4P K02930 RP-L4e; large subunit ribosomal protein L4e D Mefer_1103 ribosomal protein L7Ae/L30e/S12e/Gadd45 K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D Mefer_0789 ribosomal protein L10.e K02866 RP-L10e; large subunit ribosomal protein L10e D Mefer_0949 conserved hypothetical protein K02875 RP-L14e; large subunit ribosomal protein L14e D Mefer_1408 Ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e D Mefer_0486 ribosomal protein L15 K02883 RP-L18e; large subunit ribosomal protein L18e D Mefer_0678 Ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e D Mefer_0571 Ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e D Mefer_1101 Ribosomal protein L24E K02896 RP-L24e; large subunit ribosomal protein L24e D Mefer_1266 ribosomal protein L7Ae/L30e/S12e/Gadd45 K02908 RP-L30e; large subunit ribosomal protein L30e D Mefer_0309 Ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e D Mefer_0679 Ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e D Mefer_0947 Ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e D Mefer_0384 Ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e D Mefer_1378 ribosomal protein L37a K02921 RP-L37Ae; large subunit ribosomal protein L37Ae D Mefer_0612 Ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e D Mefer_1082 hypothetical protein K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D Mefer_0430 Ribosomal protein L44E K02929 RP-L44e; large subunit ribosomal protein L44e D Mefer_1409 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D Mefer_0691 ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D Mefer_0489 ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D Mefer_0676 ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D Mefer_1269 ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D Mefer_0681 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D Mefer_0484 ribosomal protein S9P K02996 RP-S9; small subunit ribosomal protein S9 D Mefer_1272 ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D Mefer_0488 ribosomal protein S11P K02948 RP-S11; small subunit ribosomal protein S11 D Mefer_1268 ribosomal protein S23 (S12) K02950 RP-S12; small subunit ribosomal protein S12 D Mefer_0490 ribosomal protein S13P K02952 RP-S13; small subunit ribosomal protein S13 D Mefer_0682 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D Mefer_1234 Ribosomal S13S15 domain protein K02956 RP-S15; small subunit ribosomal protein S15 D Mefer_0687 ribosomal protein S17P K02961 RP-S17; small subunit ribosomal protein S17 D Mefer_0736 ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D Mefer_0703 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D Mefer_0737 ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D Mefer_0740 ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D Mefer_0683 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Mefer_0680 ribosomal protein L6P K02933 RP-L6; large subunit ribosomal protein L6 D Mefer_0704 ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D Mefer_1446 ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Mefer_0485 ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D Mefer_0686 50S ribosomal protein L14P K02874 RP-L14; large subunit ribosomal protein L14 D Mefer_0674 ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D Mefer_0677 ribosomal protein L18P/L5E K02881 RP-L18; large subunit ribosomal protein L18 D Mefer_0692 ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D Mefer_0738 ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D Mefer_0685 ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D Mefer_0690 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Mefer_0675 ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30 D Mefer_0705 ribosomal protein 60S K02869 RP-L12; large subunit ribosomal protein L12 D Mefer_1382 Ribosomal LX protein K02944 RP-LX; large subunit ribosomal protein LX D Mefer_R0023 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Mefer_R0030 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Mefer_R0001 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Mefer_R0033 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Mefer_R0003 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Mefer_R0031 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:mfe03009] D Mefer_0107 Pre-mRNA processing ribonucleoprotein, binding domain protein K14564 NOP56; nucleolar protein 56 D Mefer_0205 rRNA pseudouridine synthase K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-] D Mefer_0819 RNA-binding protein Nop10p K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3 D Mefer_1380 Brix domain protein K14561 IMP4; U3 small nucleolar ribonucleoprotein protein IMP4 D Mefer_0800 Suppressor Mra1 family protein K14568 EMG1; rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260] D Mefer_0986 KH domain protein K06961 KRR1; ribosomal RNA assembly protein D Mefer_0987 Non-specific serine/threonine protein kinase K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1] D Mefer_0509 Non-specific serine/threonine protein kinase K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1] D Mefer_0111 Adenylate kinase K18532 AK6; adenylate kinase [EC:2.7.4.3] D Mefer_1081 Protein of unknown function DUF367 K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157] D Mefer_1073 ABC transporter related K06174 ABCE1; ATP-binding cassette, sub-family E, member 1 D Mefer_0079 small GTP-binding protein K06943 NOG1; nucleolar GTP-binding protein D Mefer_0688 Ribonuclease P, Rpp29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D Mefer_0718 Ribonuclease P K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D Mefer_0816 Ribonuclease P K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D Mefer_1419 GTPase or GTP-binding protein-like protein K06947 GRC3; polynucleotide 5'-hydroxyl-kinase GRC3/NOL9 [EC:2.7.1.-] D Mefer_0310 translation initiation factor eIF-6 K03264 EIF6; translation initiation factor 6 D Mefer_0269 NMD3 family protein K07562 NMD3; 60S ribosomal export protein NMD3 D Mefer_1377 Ribosome maturation protein SBDS-like protein K14574 SDO1; ribosome maturation protein SDO1 D Mefer_0752 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase D Mefer_0076 Protein of unknown function UPF0113 K07565 NIP7; 60S ribosome subunit biogenesis protein NIP7 D Mefer_0070 small GTP-binding protein K03595 era; GTPase D Mefer_1093 fibrillarin K04795 flpA; fibrillarin-like pre-rRNA processing protein D Mefer_1103 ribosomal protein L7Ae/L30e/S12e/Gadd45 K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D Mefer_1022 hypothetical protein K07569 gar1; RNA-binding protein D Mefer_1267 NusA family KH domain protein K02600 nusA; transcription termination/antitermination protein NusA D Mefer_0120 dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D Mefer_1472 methyltransferase small K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172] D Mefer_0008 ribosomal RNA large subunit methyltransferase J K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166] D Mefer_0268 protein of unknown function Met10 K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191] D Mefer_0729 protein of unknown function Met10 K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191] D Mefer_1532 ribosomal-protein-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D Mefer_1401 DEAD/DEAH box helicase domain protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Mefer_0294 GTP-binding proten HflX K03665 hflX; GTPase D Mefer_1143 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Mefer_0565 protein of unknown function UPF0044 K07574 yhbY; RNA-binding protein D Mefer_0537 GTPase of unknown function domain protein K06942 ychF; ribosome-binding ATPase C 03016 Transfer RNA biogenesis [BR:mfe03016] D Mefer_0688 Ribonuclease P, Rpp29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D Mefer_0718 Ribonuclease P K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D Mefer_0816 Ribonuclease P K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D Mefer_0848 RNAse P, Rpr2/Rpp21 subunit K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5] D Mefer_0900 ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11] D Mefer_0616 protein of unknown function UPF0027 K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8] D Mefer_1248 protein of unknown function DUF101 K24956 ZBTB8OS; protein archease D Mefer_1271 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha D Mefer_0007 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Mefer_0381 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Mefer_0836 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Mefer_1429 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Mefer_0039 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Mefer_0442 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Mefer_0805 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Mefer_0453 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Mefer_0144 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Mefer_0505 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Mefer_0911 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Mefer_1228 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Mefer_0725 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Mefer_1353 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Mefer_0880 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Mefer_0272 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Mefer_0190 Protein of unknown function DUF516 K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96] D Mefer_1126 histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D Mefer_1129 MiaB-like tRNA modifying enzyme K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5] D Mefer_0834 N2,N2-dimethylguanosine tRNA methyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216] D Mefer_1473 protein of unknown function Met10 K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D Mefer_1156 tRNA (adenine-N(1)-)-methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220] D Mefer_0099 Wyosine base formation domain protein K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44] D Mefer_1490 protein of unknown function Met10 K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114] D Mefer_0050 Protein of unknown function DUF207 K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282] D Mefer_0972 tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D Mefer_1350 tRNA pseudouridine synthase D TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27] D Mefer_1371 tRNA pseudouridine synthase D TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27] D Mefer_0572 THUMP domain protein K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25] D Mefer_1149 histone acetyltransferase, ELP3 family K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311] D Mefer_1143 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Mefer_0826 selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3] D Mefer_0032 THUMP domain protein K06963 TAN1; tRNA acetyltransferase TAN1 D Mefer_1298 THUMP domain protein K06963 TAN1; tRNA acetyltransferase TAN1 D Mefer_R0029 rnpB; RNA component of RNaseP K01978 rnpB; M1 RNA D Mefer_0839 Protein of unknown function UPF0278 K09006 K09006; RNA-free ribonuclease P [EC:3.1.26.5] D Mefer_0305 CCA-adding enzyme K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72] D Mefer_1397 tRNA intron endonuclease K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16] D Mefer_0546 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58] D Mefer_0785 lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Mefer_1488 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D Mefer_0735 O-phosphoseryl-tRNA(Cys) synthetase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27] D Mefer_0975 Sep-tRNA K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73] D Mefer_1462 RNA methyltransferase, TrmH family, group 1 K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-] D Mefer_1329 protein of unknown function DUF358 K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257] D Mefer_1246 RNA methylase, NOL1/NOP2/sun family K22901 trm4; tRNA (cytosine40_48-C5)-methyltransferase [EC:2.1.1.-] D Mefer_0982 putative RNA methylase K16318 trm14; tRNA (guanine6-N2)-methyltransferase [EC:2.1.1.256] D Mefer_1079 putative RNA methylase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213] D Mefer_0592 protein of unknown function DUF127 K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206] D Mefer_1461 PP-loop domain protein K21947 ttuA; tRNA-5-methyluridine54 2-sulfurtransferase [EC:2.8.1.15] D Mefer_1497 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D Mefer_0290 metalloendopeptidase, glycoprotease family K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1] D Mefer_1381 Protein of unknown function DUF2144 K09741 pcc1; KEOPS complex subunit Pcc1 D Mefer_0176 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D Mefer_0047 6-pyruvoyl tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D Mefer_0262 Radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D Mefer_1285 Rhodanese domain protein K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3] D Mefer_1286 ATPase-like protein K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3] D Mefer_0980 archaeosine tRNA-ribosyltransferase K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48] D Mefer_0763 thiamine biosynthesis/tRNA modification protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D Mefer_1336 domain of unknown function DUF1743 K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22] C 03012 Translation factors [BR:mfe03012] D Mefer_0988 translation initiation factor eIF-1A K03236 EIF1A; translation initiation factor 1A D Mefer_0689 translation initiation factor SUI1 K03113 EIF1; translation initiation factor 1 D Mefer_0818 translation initiation factor 2, alpha subunit K03237 EIF2S1; translation initiation factor 2 subunit 1 D Mefer_0385 translation initiation factor aIF-2, beta subunit K03238 EIF2S2; translation initiation factor 2 subunit 2 D Mefer_0037 small GTP-binding protein K03242 EIF2S3; translation initiation factor 2 subunit 3 D Mefer_0578 translation initiation factor eIF-5A K03263 EIF5A; translation initiation factor 5A D Mefer_0365 translation initiation factor aIF-2 K03243 EIF5B; translation initiation factor 5B D Mefer_0310 translation initiation factor eIF-6 K03264 EIF6; translation initiation factor 6 D Mefer_1271 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha D Mefer_0693 translation elongation factor aEF-1 beta K03232 EEF1B; elongation factor 1-beta D Mefer_1270 translation elongation factor aEF-2 K03234 EEF2; elongation factor 2 D Mefer_0717 selenocysteine-specific translation elongation factor K03833 selB; selenocysteine-specific elongation factor D Mefer_0668 diphthamide biosynthesis protein K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108] D Mefer_0771 ATP binding protein K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14] D Mefer_0919 eRF1 domain 2 protein K03265 ETF1; peptide chain release factor subunit 1 D Mefer_0596 methylase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D Mefer_1284 Aminoacyl-tRNA hydrolase K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29] C 03110 Chaperones and folding catalysts [BR:mfe03110] D Mefer_1227 thermosome K22447 cct; archaeal chaperonin D Mefer_0858 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein D Mefer_0841 prefoldin, alpha subunit K04797 pfdA; prefoldin alpha subunit D Mefer_1500 prefoldin, beta subunit K04798 pfdB; prefoldin beta subunit D Mefer_0466 hydrogenase nickel insertion protein HypA K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF D Mefer_0985 hydrogenase accessory protein HypB K04652 hypB; hydrogenase nickel incorporation protein HypB D Mefer_0916 peptidylprolyl isomerase FKBP-type K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8] D Mefer_1333 redox-active disulfide protein 1 K03671 TXN; thioredoxin C 04131 Membrane trafficking [BR:mfe04131] D Mefer_0026 Nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Mefer_0752 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase D Mefer_0813 arsenite-activated ATPase ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Mefer_1448 protein translocase SEC61 complex, gamma subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D Mefer_0345 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Mefer_1271 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha C 04121 Ubiquitin system [BR:mfe04121] D Mefer_1082 hypothetical protein K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D Mefer_0876 Ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae C 03051 Proteasome [BR:mfe03051] D Mefer_1376 proteasome endopeptidase complex, alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D Mefer_0382 proteasome endopeptidase complex, beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D Mefer_0150 26S proteasome subunit P45 family K03420 psmR; proteasome regulatory subunit C 03032 DNA replication proteins [BR:mfe03032] D Mefer_0749 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1 D Mefer_0432 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen D Mefer_1010 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D Mefer_0746 DNA ligase I, ATP-dependent Dnl1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D Mefer_0804 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mefer_1100 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mefer_0819 RNA-binding protein Nop10p K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3 D Mefer_0205 rRNA pseudouridine synthase K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-] D Mefer_1106 TOPRIM domain protein K02316 dnaG; DNA primase [EC:2.7.7.101] D Mefer_1152 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D Mefer_0847 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D Mefer_1579 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D Mefer_1610 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D Mefer_0931 DNA primase, small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102] D Mefer_1089 DNA primase, large subunit K18882 priL; DNA primase large subunit D Mefer_1155 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Mefer_1468 DNA-directed DNA polymerase K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D Mefer_1319 DNA polymerase II, large subunit DP2 K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7] D Mefer_1088 DNA-directed DNA polymerase K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7] D Mefer_1474 AAA ATPase central domain protein K04800 rfcL; replication factor C large subunit D Mefer_1399 Replication factor C K04801 rfcS; replication factor C small subunit D Mefer_1450 DNA topoisomerase (ATP-hydrolyzing) K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2] D Mefer_0124 DNA topoisomerase VI, B subunit K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2] D Mefer_0728 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D Mefer_0049 reverse gyrase K03170 topG; reverse gyrase [EC:5.6.2.2 5.6.2.-] C 03036 Chromosome and associated proteins [BR:mfe03036] D Mefer_0804 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mefer_1100 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mefer_0188 Transcription factor CBF/NF-Y/histone domain protein K24450 hmf; DNA-binding protein D Mefer_0859 Transcription factor CBF/NF-Y/histone domain protein K24450 hmf; DNA-binding protein D Mefer_0033 Transcription factor CBF/NF-Y/histone domain protein K24450 hmf; DNA-binding protein D Mefer_0181 Uncharacterized host factor I protein-like protein K03666 hfq; host factor-I protein D Mefer_0868 chromosome segregation protein SMC K03529 smc; chromosome segregation protein D Mefer_0285 chromosome segregation and condensation protein ScpA K05896 scpA; segregation and condensation protein A D Mefer_0992 hypothetical protein K06024 scpB; segregation and condensation protein B D Mefer_0206 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Mefer_1449 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Mefer_0793 cell division ATPase MinD K03609 minD; septum site-determining protein MinD D Mefer_0748 cell division ATPase MinD K03609 minD; septum site-determining protein MinD D Mefer_0074 chromosome partitioning ATPase-like protein K03609 minD; septum site-determining protein MinD D Mefer_1582 integrase family protein K04763 xerD; integrase/recombinase XerD D Mefer_0420 ATPase-like, ParA/MinD K03593 mrp; ATP-binding protein involved in chromosome partitioning C 03400 DNA repair and recombination proteins [BR:mfe03400] D Mefer_1531 methylated-DNA/protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D Mefer_0216 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D Mefer_0432 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen D Mefer_1010 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D Mefer_0746 DNA ligase I, ATP-dependent Dnl1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D Mefer_0749 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1 D Mefer_0807 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Mefer_0781 deoxyUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D Mefer_1161 Xylose isomerase domain protein TIM barrel K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D Mefer_0921 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Mefer_0851 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Mefer_0661 SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50 D Mefer_0662 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11 D Mefer_1438 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1 D Mefer_1131 DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA D Mefer_0103 DNA repair and recombination protein RadB K04484 radB; DNA repair protein RadB D Mefer_0715 Resolvase, Holliday junction-type K03552 hjr; holliday junction resolvase [EC:3.1.21.10] D Mefer_0549 protein of unknown function DUF87 K06915 herA; DNA double-strand break repair helicase HerA and related ATPase D Mefer_0038 NurA domain protein K25510 nurA; DNA double-strand break repair nuclease NurA [EC:3.1.-.-] D Mefer_0296 DEAD/DEAH box helicase domain protein K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4] D Mefer_0728 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D Mefer_0832 helicase c2 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D Mefer_0564 DEAD/H associated domain protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] D Mefer_0870 Protein of unknown function DUF650 K22585 nreA; DNA repair protein NreA C 03029 Mitochondrial biogenesis [BR:mfe03029] D Mefer_0688 Ribonuclease P, Rpp29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D Mefer_0718 Ribonuclease P K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D Mefer_0816 Ribonuclease P K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D Mefer_0070 small GTP-binding protein K03595 era; GTPase D Mefer_0880 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Mefer_1429 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Mefer_0453 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Mefer_0442 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Mefer_1389 glutamyl-tRNA(Gln) amidotransferase, A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D Mefer_0196 glutamyl-tRNA(Gln) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Mefer_0436 Asp/Glu amidotransferase, subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D Mefer_0420 ATPase-like, ParA/MinD K03593 mrp; ATP-binding protein involved in chromosome partitioning B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:mfe02000] D Mefer_1160 molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 modA; molybdate transport system substrate-binding protein D Mefer_1159 NifC-like ABC-type porter K02018 modB; molybdate transport system permease protein D Mefer_1158 ABC transporter related K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D Mefer_0233 extracellular solute-binding protein family 1 K15495 wtpA; molybdate/tungstate transport system substrate-binding protein D Mefer_0016 binding-protein-dependent transport systems inner membrane component K15496 wtpB; molybdate/tungstate transport system permease protein D Mefer_0017 ABC transporter related K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6] D Mefer_0146 ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic components K15553 ssuA; sulfonate transport system substrate-binding protein D Mefer_1306 binding-protein-dependent transport systems inner membrane component K15554 ssuC; sulfonate transport system permease protein D Mefer_1307 ABC transporter related K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D Mefer_0337 binding-protein-dependent transport systems inner membrane component K05846 opuBD; osmoprotectant transport system permease protein D Mefer_0865 conserved hypothetical protein K02069 STAR2; UDP-glucose/iron transport system permease protein D Mefer_0905 phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D Mefer_0906 phosphate ABC transporter, inner membrane subunit PstC K02037 pstC; phosphate transport system permease protein D Mefer_0907 phosphate ABC transporter, inner membrane subunit PstA K02038 pstA; phosphate transport system permease protein D Mefer_0908 phosphate ABC transporter, ATPase subunit K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Mefer_0492 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein D Mefer_0491 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein D Mefer_0494 ABC transporter related K01995 livG; branched-chain amino acid transport system ATP-binding protein D Mefer_0401 periplasmic binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D Mefer_0394 transport system permease protein K02015 ABC.FEV.P; iron complex transport system permease protein D Mefer_0393 ABC transporter related K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-] D Mefer_0903 periplasmic binding protein K25034 btuF; cobalamin transport system substrate-binding protein D Mefer_1139 periplasmic binding protein K25034 btuF; cobalamin transport system substrate-binding protein D Mefer_1142 transport system permease protein K25027 btuC; cobalamin transport system permease protein D Mefer_1141 transport system permease protein K25027 btuC; cobalamin transport system permease protein D Mefer_1140 ABC transporter related K25028 btuD; cobalamin transport system ATP-binding protein [EC:7.6.2.8] D Mefer_1342 cobalt transport protein K02009 cbiN; cobalt/nickel transport protein D Mefer_0541 hypothetical protein K02009 cbiN; cobalt/nickel transport protein D Mefer_1343 cobalt ABC transporter, inner membrane subunit CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein D Mefer_0540 cobalt ABC transporter, inner membrane subunit CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein D Mefer_0542 cobalamin (vitamin B12) biosynthesis CbiM protein K02007 cbiM; cobalt/nickel transport system permease protein D Mefer_1341 cobalamin biosynthesis protein CbiM K02007 cbiM; cobalt/nickel transport system permease protein D Mefer_1344 cobalt ABC transporter, ATPase subunit K02006 cbiO; cobalt/nickel transport system ATP-binding protein D Mefer_1527 BioY protein K03523 bioY; biotin transport system substrate-specific component D Mefer_1134 daunorubicin resistance ABC transporter, inner membrane subunit B K01992 ABC-2.P; ABC-2 type transport system permease protein D Mefer_1135 daunorubicin resistance ABC transporter ATPase subunit K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Mefer_0224 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Mefer_0223 ABC transporter related K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Mefer_1235 ABC transporter related K09013 sufC; Fe-S cluster assembly ATP-binding protein D Mefer_0628 anion transporter K14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5 D Mefer_1080 MATE efflux family protein K26937 dinF; MATE family, multidrug efflux pump D Mefer_0573 TrkA-N domain protein K10716 kch; voltage-gated potassium channel D Mefer_0597 TrkA-N domain protein K10716 kch; voltage-gated potassium channel D Mefer_0359 Ion transport 2 domain protein K10716 kch; voltage-gated potassium channel D Mefer_0606 ammonium transporter K03320 amt; ammonium transporter, Amt family D Mefer_0650 formate/nitrite transporter K21993 fdhC; formate transporter D Mefer_0747 MscS Mechanosensitive ion channel K16052 ynaI; MscS family membrane protein D Mefer_0745 MscS Mechanosensitive ion channel K16052 ynaI; MscS family membrane protein D Mefer_1255 magnesium and cobalt transport protein CorA K03284 corA; magnesium transporter D Mefer_0588 CrcB protein K06199 crcB; fluoride exporter D Mefer_1258 zinc/iron permease K07238 TC.ZIP; zinc transporter, ZIP family D Mefer_0535 protein of unknown function DUF6 transmembrane K08978 TC.BAT1; bacterial/archaeal transporter family protein D Mefer_0391 Na+/Ca+ antiporter, CaCA family K07301 yrbG; cation:H+ antiporter D Mefer_0605 sodium/hydrogen exchanger K11105 cvrA; potassium/hydrogen antiporter D Mefer_0043 sodium/hydrogen exchanger K26730 napA; Na+:H+ antiporter D Mefer_1455 cation transporter K03498 trkH; trk/ktr system potassium uptake protein D Mefer_0019 TrkA-N domain protein K03499 trkA; trk/ktr system potassium uptake protein D Mefer_1502 Xanthine/uracil/vitamin C permease K06901 pbuG; adenine/guanine/hypoxanthine permease D Mefer_1335 Cl-channel voltage-gated family protein K03281 clcA; chloride channel protein, CIC family D Mefer_1074 chromate transporter, chromate ion transporter (CHR) family K07240 chrA; chromate transporter D Mefer_0813 arsenite-activated ATPase ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Mefer_0118 auxin efflux carrier K24180 mleP; malate permease and related proteins D Mefer_0974 multiple antibiotic resistance (MarC)-related protein K05595 marC; multiple antibiotic resistance protein D Mefer_0853 multiple antibiotic resistance (MarC)-related protein K05595 marC; multiple antibiotic resistance protein D Mefer_1340 high-affinity nickel-transporter K08970 rcnA; nickel/cobalt transporter (NicO) family protein D Mefer_0343 conserved hypothetical protein K15383 K15383; MtN3 and saliva related transmembrane protein D Mefer_0768 FeoA family protein K04758 feoA; ferrous iron transport protein A D Mefer_0767 ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B C 02044 Secretion system [BR:mfe02044] D Mefer_1215 flagellin K07325 flaB; archaeal flagellin FlaB D Mefer_1214 flagellin K07325 flaB; archaeal flagellin FlaB D Mefer_1213 flagellin K07325 flaB; archaeal flagellin FlaB D Mefer_1212 Flagella accessory C family protein K07822 flaC; archaeal flagellar protein FlaC D Mefer_1211 flagella protein K07327 flaD; archaeal flagellar protein FlaD D Mefer_1210 flagella protein K07328 flaE; archaeal flagellar protein FlaE D Mefer_1209 flagellin K07329 flaF; archaeal flagellar protein FlaF D Mefer_1208 flagellin K07330 flaG; archaeal flagellar protein FlaG D Mefer_1207 flagella biogenesis ATPase-like protein K07331 flaH; archaeal flagellar protein FlaH D Mefer_1206 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI D Mefer_0090 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI D Mefer_1024 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI D Mefer_1205 Type II secretion system F domain protein K07333 flaJ; archaeal flagellar protein FlaJ D Mefer_0089 Type II secretion system F domain protein K07333 flaJ; archaeal flagellar protein FlaJ D Mefer_1025 Type II secretion system F domain protein K07333 flaJ; archaeal flagellar protein FlaJ D Mefer_1026 Type II secretion system F domain protein K07333 flaJ; archaeal flagellar protein FlaJ D Mefer_0927 Peptidase A24A domain protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D Mefer_1204 Peptidase A24B, FlaK domain protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D Mefer_0085 Peptidase A24B, FlaK domain protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D Mefer_0342 SecD/SecF/SecDF export membrane protein K03072 secD; preprotein translocase subunit SecD D Mefer_0028 SecD/SecF/SecDF export membrane protein K03074 secF; preprotein translocase subunit SecF D Mefer_0673 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Mefer_0354 GTP-binding signal recognition particle SRP54 G-domain protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Mefer_0002 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Mefer_1448 protein translocase SEC61 complex, gamma subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D Mefer_1256 Ribonucleoprotein complex SRP, Srp19 component K03105 SRP19; signal recognition particle subunit SRP19 C 02042 Bacterial toxins C 02022 Two-component system [BR:mfe02022] D Mefer_0648 integral membrane sensor signal transduction histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3] D Mefer_0640 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Mefer_1110 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Mefer_0641 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] C 02035 Bacterial motility proteins [BR:mfe02035] D Mefer_0640 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Mefer_0642 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW D Mefer_1108 CheC, inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC D Mefer_1109 CheC, inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC D Mefer_0639 CheD, stimulates methylation of MCP protein K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44] D Mefer_1107 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Mefer_0641 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Mefer_1110 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Mefer_1112 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Mefer_0753 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Mefer_0025 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Mefer_1215 flagellin K07325 flaB; archaeal flagellin FlaB D Mefer_1214 flagellin K07325 flaB; archaeal flagellin FlaB D Mefer_1213 flagellin K07325 flaB; archaeal flagellin FlaB D Mefer_1212 Flagella accessory C family protein K07822 flaC; archaeal flagellar protein FlaC D Mefer_1211 flagella protein K07327 flaD; archaeal flagellar protein FlaD D Mefer_1210 flagella protein K07328 flaE; archaeal flagellar protein FlaE D Mefer_1209 flagellin K07329 flaF; archaeal flagellar protein FlaF D Mefer_1208 flagellin K07330 flaG; archaeal flagellar protein FlaG D Mefer_1207 flagella biogenesis ATPase-like protein K07331 flaH; archaeal flagellar protein FlaH D Mefer_1206 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI D Mefer_0090 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI D Mefer_1024 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI D Mefer_1205 Type II secretion system F domain protein K07333 flaJ; archaeal flagellar protein FlaJ D Mefer_0089 Type II secretion system F domain protein K07333 flaJ; archaeal flagellar protein FlaJ D Mefer_1025 Type II secretion system F domain protein K07333 flaJ; archaeal flagellar protein FlaJ D Mefer_1026 Type II secretion system F domain protein K07333 flaJ; archaeal flagellar protein FlaJ D Mefer_0927 Peptidase A24A domain protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D Mefer_1204 Peptidase A24B, FlaK domain protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D Mefer_0085 Peptidase A24B, FlaK domain protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:mfe04812] D Mefer_1184 protein of unknown function DUF52 K06990 MEMO1; MEMO1 family protein D Mefer_0206 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Mefer_1449 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Mefer_0793 cell division ATPase MinD K03609 minD; septum site-determining protein MinD D Mefer_0748 cell division ATPase MinD K03609 minD; septum site-determining protein MinD D Mefer_0074 chromosome partitioning ATPase-like protein K03609 minD; septum site-determining protein MinD C 04147 Exosome [BR:mfe04147] D Mefer_0447 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Mefer_0256 Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Mefer_0345 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Mefer_1054 Peroxiredoxin K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24] D Mefer_1271 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha D Mefer_1270 translation elongation factor aEF-2 K03234 EEF2; elongation factor 2 D Mefer_1516 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Mefer_1010 flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D Mefer_1507 inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D Mefer_0876 Ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D Mefer_0752 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase D Mefer_1126 histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D Mefer_1483 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Mefer_0672 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Mefer_0731 phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Mefer_1000 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Mefer_1293 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Mefer_0175 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Mefer_0258 Porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D Mefer_0636 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Mefer_0246 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Mefer_1530 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 02048 Prokaryotic defense system [BR:mfe02048] D Mefer_1438 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1 D Mefer_1430 CRISPR-associated protein Cas2 K09951 cas2; CRISPR-associated protein Cas2 D Mefer_1440 CRISPR-associated helicase Cas3 K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] D Mefer_1433 CRISPR-associated helicase Cas3 K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] D Mefer_1432 CRISPR-associated HD domain protein K07475 cas3; CRISPR-associated endonuclease Cas3-HD [EC:3.1.-.-] D Mefer_1436 CRISPR-associated autoregulator, DevR family K19074 csa2; CRISPR-associated protein Csa2 D Mefer_1431 transcriptional regulator, ArsR family K07725 csa3; CRISPR-associated protein Csa3 D Mefer_1442 CRISPR-associated autoregulator, DevR family K19075 cst2; CRISPR-associated protein Cst2 D Mefer_1439 CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] D Mefer_1435 CRISPR-associated protein Cas5 family K19089 cas5a_b_c; CRISPR-associated protein Cas5a/b/c D Mefer_1444 CRISPR-associated protein Cas6 K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-] D Mefer_1441 CRISPR-associated protein Cas5 K19116 cas5h; CRISPR-associated protein Cas5h D Mefer_0971 CRISPR-associated protein, Csm1 family K07016 csm1; CRISPR-associated protein Csm1 D Mefer_0970 CRISPR-associated protein, Csm2 family K19138 csm2; CRISPR-associated protein Csm2 D Mefer_0969 CRISPR-associated RAMP protein, Csm3 family K09002 csm3; CRISPR-associated protein Csm3 D Mefer_0968 CRISPR-associated RAMP protein, Csm4 family K19139 csm4; CRISPR-associated protein Csm4 D Mefer_0967 CRISPR-associated RAMP protein, Csm5 family K19140 csm5; CRISPR-associated protein Csm5 D Mefer_0276 protein of unknown function DUF324 K07061 cmr1; CRISPR-associated protein Cmr1 D Mefer_0277 protein of unknown function DUF324 K19076 cmr2; CRISPR-associated protein Cmr2 D Mefer_0966 CRISPR-associated protein, MJ1666 family K19143 csx1; CRISPR-associated protein Csx1 D Mefer_0250 Type I site-specific deoxyribonuclease K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D Mefer_0776 type I site-specific deoxyribonuclease, HsdR family K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D Mefer_0253 restriction modification system DNA specificity domain protein K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D Mefer_0775 restriction modification system DNA specificity domain protein K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D Mefer_0254 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D Mefer_0774 Site-specific DNA-methyltransferase (adenine-specific) K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D Mefer_0543 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D Mefer_0896 DNA methylase N-4/N-6 domain protein K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] D Mefer_0804 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mefer_1100 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Mefer_1611 restriction endonuclease K07448 mrr; restriction system protein D Mefer_0206 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Mefer_1449 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Mefer_0007 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Mefer_1218 PilT protein domain protein K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules C 01504 Antimicrobial resistance genes C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:mfe03100] D Mefer_R0009 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Mefer_R0002 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Mefer_R0032 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Mefer_R0014 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Mefer_R0018 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Mefer_R0026 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Mefer_R0038 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Mefer_R0024 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Mefer_R0013 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Mefer_R0028 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Mefer_R0025 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Mefer_R0036 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Mefer_R0005 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Mefer_R0004 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Mefer_R0034 tRNA-His K14226 tRNA-His; tRNA His D Mefer_R0016 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Mefer_R0010 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Mefer_R0035 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Mefer_R0006 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Mefer_R0022 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Mefer_R0037 tRNA-Met K14230 tRNA-Met; tRNA Met D Mefer_R0041 tRNA-Met K14230 tRNA-Met; tRNA Met D Mefer_R0007 tRNA-Met K14230 tRNA-Met; tRNA Met D Mefer_R0039 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Mefer_R0011 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Mefer_R0020 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Mefer_R0045 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Mefer_R0042 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Mefer_R0012 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Mefer_R0027 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Mefer_R0019 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Mefer_R0008 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Mefer_R0021 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Mefer_R0040 tRNA-Val K14237 tRNA-Val; tRNA Val D Mefer_R0043 tRNA-Val K14237 tRNA-Val; tRNA Val D Mefer_R0017 tRNA-Val K14237 tRNA-Val; tRNA Val D Mefer_R0015 tRNA-Sec K14238 tRNA-Sec; tRNA Sec D Mefer_R0001 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Mefer_R0033 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Mefer_R0003 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Mefer_R0031 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Mefer_R0023 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Mefer_R0030 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Mefer_R0044 ffs; SRP RNA; RNA component of signal recognitionparti cle K01983 ffs; SRP RNA D Mefer_R0029 rnpB; RNA component of RNaseP K01978 rnpB; M1 RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D Mefer_0899 NADPH-dependent F420 reductase K06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40] D Mefer_1066 beta-lactamase domain protein K19817 fprA; coenzyme F420H2 oxidase [EC:1.5.3.22] D Mefer_0567 pyridine nucleotide-disulphide oxidoreductase dimerization region K17870 nox1; NADH oxidase (H2O2-forming) [EC:1.6.3.3] D Mefer_1132 nitrite and sulphite reductase 4Fe-4S region K21816 fsr; sulfite reductase (coenzyme F420) [EC:1.8.98.3] D Mefer_0209 Radical SAM domain protein K06937 E1.21.98.5; tetraether lipid synthase [EC:1.21.98.5] D Mefer_0579 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Mefer_1324 Radical SAM domain protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Mefer_1174 Radical SAM domain protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Mefer_0744 protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] D Mefer_0044 diphthine synthase K20215 dph5; diphthine synthase [EC:2.1.1.98] D Mefer_0933 methanogenesis marker protein 10 K25222 mmp10; [methyl coenzyme M reductase]-L-arginine C-5-methyltransferase [EC:2.1.1.379] D Mefer_1040 Protein of unknown function DUF166 K22882 K22882; thymidylate synthase [EC:2.1.1.-] D Mefer_0110 Carbamoyltransferase K00612 nodU; carbamoyltransferase [EC:2.1.3.-] D Mefer_0149 glycosyl transferase group 1 K00754 bshA; L-malate glycosyltransferase [EC:2.4.1.-] D Mefer_1179 deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46] D Mefer_0046 protein of unknown function DUF43 K07057 bpsA; N4-bis(aminopropyl)spermidine synthase [EC:2.5.1.128] D Mefer_0624 protein of unknown function DUF43 K07057 bpsA; N4-bis(aminopropyl)spermidine synthase [EC:2.5.1.128] D Mefer_0191 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143] D Mefer_0631 PUA domain containing protein K07557 tgtA2; archaeosine synthase alpha-subunit [EC:2.6.1.97 2.6.1.-] D Mefer_0796 Radical SAM domain protein K06936 raSEA; archaeosine synthase beta-subunit [EC:2.6.1.-] D Mefer_1150 phosphatidate cytidylyltransferase K18678 VTE5; phytol kinase [EC:2.7.1.182] D Mefer_1456 ATP-cone domain protein K05715 2PGK; 2-phosphoglycerate kinase [EC:2.7.2.16] D Mefer_1230 protein of unknown function DUF147 K18672 dacA; diadenylate cyclase [EC:2.7.7.85] D Mefer_0477 protein of unknown function DUF89 K09116 K09116; damage-control phosphatase, subfamily I [EC:3.1.3.-] D Mefer_0757 hydrolase, TatD family K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D Mefer_0185 nuclease (SNase domain protein) K01174 nuc; micrococcal nuclease [EC:3.1.31.1] D Mefer_1045 DNA-(apurinic or apyrimidinic site) lyase K03653 K03653; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] D Mefer_0408 ATPase associated with various cellular activities AAA_5 K03924 moxR; MoxR-like ATPase [EC:3.6.3.-] D Mefer_1177 ATPase associated with various cellular activities AAA_5 K03924 moxR; MoxR-like ATPase [EC:3.6.3.-] D Mefer_1096 carbohydrate kinase, YjeF related protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6] D Mefer_0920 thiamine biosynthesis protein K06864 larE; pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase [EC:4.4.1.37] D Mefer_0591 protein of unknown function DUF111 K09121 larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12] D Mefer_1007 CoA-substrate-specific enzyme activase K23876 hgdC; (R)-2-hydroxyacyl-CoA dehydratese activating ATPase [EC:5.6.1.9] D Mefer_1337 methanogenesis marker protein 1 K24409 ycaO; thioglycine synthase [EC:6.2.2.1] D Mefer_1247 RNA 3'-phosphate cyclase K01974 RTCA; RNA 3'-terminal phosphate cyclase (ATP) [EC:6.5.1.4] D Mefer_1305 ATP dependent DNA ligase K07468 K07468; DNA/RNA ligase [EC:6.5.1.-] D Mefer_0335 4Fe-4S ferredoxin iron-sulfur binding domain protein K03616 rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] D Mefer_0336 4Fe-4S ferredoxin iron-sulfur binding domain protein K03616 rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] D Mefer_1237 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10] C 99981 Carbohydrate metabolism C 99982 Energy metabolism D Mefer_1068 Rubrerythrin K19824 fprB; rubrerythrin D Mefer_0563 formate dehydrogenase family accessory protein FdhD K02379 fdhD; FdhD protein D Mefer_1050 beta-lactamase domain protein K12264 norV; anaerobic nitric oxide reductase flavorubredoxin D Mefer_1338 Radical SAM domain protein K02585 nifB; nitrogen fixation protein NifB D Mefer_0319 membrane protein-like protein K14092 ehaA; energy-converting hydrogenase A subunit A D Mefer_0320 membrane protein-like protein K14093 ehaB; energy-converting hydrogenase A subunit B D Mefer_0321 Protein of unknown function DUF2109, membrane K14094 ehaC; energy-converting hydrogenase A subunit C D Mefer_0322 Protein of unknown function DUF2108, membrane K14095 ehaD; energy-converting hydrogenase A subunit D D Mefer_0323 (NiFe)-hydrogenase-3-type complex Eha, membrane protein EhaE K14096 ehaE; energy-converting hydrogenase A subunit E D Mefer_0324 (NiFe)-hydrogenase-3-type complex Eha, membrane protein EhaF K14097 ehaF; energy-converting hydrogenase A subunit F D Mefer_0325 Protein of unknown function DUF2105, membrane K14098 ehaG; energy-converting hydrogenase A subunit G D Mefer_0326 (NiFe)-hydrogenase-3-type complex Eha, membrane protein EhaH, predicted K14099 ehaH; energy-converting hydrogenase A subunit H D Mefer_0327 hypothetical protein K14100 ehaI; energy-converting hydrogenase A subunit I D Mefer_0328 respiratory-chain NADH dehydrogenase subunit 1 K14101 ehaJ; energy-converting hydrogenase A subunit J D Mefer_0329 hypothetical protein K14102 ehaK; energy-converting hydrogenase A subunit K D Mefer_0330 Protein of unknown function DUF2104, membrane K14103 ehaL; energy-converting hydrogenase A subunit L D Mefer_0331 (NiFe)-hydrogenase-3-type complex Eha, EhaM K14104 ehaM; energy-converting hydrogenase A subunit M D Mefer_0332 NADH ubiquinone oxidoreductase 20 kDa subunit K14105 ehaN; energy-converting hydrogenase A subunit N D Mefer_0333 NADH dehydrogenase (quinone) K14106 ehaO; energy-converting hydrogenase A subunit O D Mefer_0334 4Fe-4S ferredoxin iron-sulfur binding domain protein K14107 ehaP; energy-converting hydrogenase A subunit P D Mefer_0842 cation antiporter K14110 ehbA; energy-converting hydrogenase B subunit A D Mefer_0584 hypothetical protein K14111 ehbB; energy-converting hydrogenase B subunit B D Mefer_0001 Multisubunit Na+/H+ antiporter MnhG subunit-like protein K14112 ehbC; energy-converting hydrogenase B subunit C D Mefer_0981 conserved hypothetical protein K14113 ehbD; energy-converting hydrogenase B subunit D D Mefer_0058 NADH-ubiquinone oxidoreductase chain 4L K14114 ehbE; energy-converting hydrogenase B subunit E D Mefer_0057 NADH/Ubiquinone/plastoquinone (complex I) K14115 ehbF; energy-converting hydrogenase B subunit F D Mefer_0056 hypothetical protein K14116 ehbG; energy-converting hydrogenase B subunit G D Mefer_0055 Na+/H+ antiporter MnhB subunit-related protein K14118 ehbI; energy-converting hydrogenase B subunit I D Mefer_0054 hypothetical protein K14119 ehbJ; energy-converting hydrogenase B subunit J D Mefer_0053 4Fe-4S ferredoxin iron-sulfur binding domain protein K14120 ehbK; energy-converting hydrogenase B subunit K D Mefer_0052 4Fe-4S ferredoxin iron-sulfur binding domain protein K14121 ehbL; energy-converting hydrogenase B subunit L D Mefer_0131 NADH ubiquinone oxidoreductase 20 kDa subunit K14122 ehbM; energy-converting hydrogenase B subunit M D Mefer_0125 NADH dehydrogenase (ubiquinone), 30 kDa subunit K14123 ehbN; energy-converting hydrogenase B subunit N D Mefer_0132 Formate hydrogenlyase subunit 4-like protein K14124 ehbO; energy-converting hydrogenase B subunit O D Mefer_0182 Energy-converting hydrogenase B, subunit P K14125 ehbP; energy-converting hydrogenase B subunit P D Mefer_1147 amino acid-binding ACT domain protein K06862 ehbQ; energy-converting hydrogenase B subunit Q D Mefer_1038 4Fe-4S ferredoxin iron-sulfur binding domain protein K02574 napH; ferredoxin-type protein NapH C 99983 Lipid metabolism C 99984 Nucleotide metabolism C 99985 Amino acid metabolism C 99986 Glycan metabolism D Mefer_0504 conserved hypothetical protein K07027 K07027; glycosyltransferase 2 family protein D Mefer_0956 conserved hypothetical protein K07027 K07027; glycosyltransferase 2 family protein C 99987 Cofactor metabolism D Mefer_0663 molybdopterin-guanine dinucleotide biosynthesis protein B K03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein C 99988 Secondary metabolism C 99999 Others B B 09192 Unclassified: genetic information processing C 99973 Transcription D Mefer_1370 transcriptional regulator, XRE family K03627 MBF1; putative transcription factor D Mefer_0468 DNA-binding protein Alba K03622 ssh10b; archaea-specific DNA-binding protein D Mefer_0575 putative signal transduction protein with CBS domains K07744 K07744; transcriptional regulator D Mefer_0108 transcriptional regulator protein-like protein K07745 K07745; transcriptional regulator C 99974 Translation D Mefer_0569 Protein of unknown function DUF655 K07572 K07572; putative nucleotide binding protein D Mefer_0427 beta-lactamase domain protein K07577 K07577; putative mRNA 3-end processing factor D Mefer_0660 stem cell self-renewal protein Piwi domain protein K07578 K07578; homologs of the eukaryotic argonaute protein D Mefer_0857 methyltransferase small K07579 K07579; putative methylase D Mefer_0694 Protein of unknown function DUF1610 K07580 K07580; Zn-ribbon RNA-binding protein D Mefer_0467 Protein of unknown function DUF54 K07581 K07581; RNA-binding protein D Mefer_0611 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain protein-like protein K07585 K07585; tRNA methyltransferase C 99975 Protein processing D Mefer_0479 hydrogenase assembly chaperone hypC/hupF K04653 hypC; hydrogenase expression/formation protein HypC D Mefer_1495 hydrogenase expression/formation protein HypD K04654 hypD; hydrogenase expression/formation protein HypD D Mefer_0623 hydrogenase expression/formation protein HypE K04655 hypE; hydrogenase expression/formation protein HypE D Mefer_1076 (NiFe) hydrogenase maturation protein HypF K04656 hypF; hydrogenase maturation protein HypF D Mefer_1280 AIR synthase related protein domain protein K07388 K07388; hydrogenase expression/formation protein D Mefer_0892 AAA ATPase central domain protein K07392 PRS2; AAA family ATPase C 99976 Replication and repair D Mefer_0449 DNA binding domain protein, excisionase family K07450 K07450; putative resolvase D Mefer_1171 HhH-GPD family protein K07457 K07457; endonuclease III related protein D Mefer_0997 SMC domain protein K07459 ybjD; putative ATP-dependent endonuclease of the OLD family D Mefer_1098 phosphoesterase RecJ domain protein K07463 K07463; archaea-specific RecJ-like exonuclease D Mefer_0741 Translin K07477 K07477; translin D Mefer_0450 transposase, IS605 OrfB family K07496 K07496; putative transposase C 99979 Viral proteins C 99998 Others B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D Mefer_1426 phosphate transporter K03306 TC.PIT; inorganic phosphate transporter, PiT family C 99978 Cell growth D Mefer_0402 Cobyrinic acid ac-diamide synthase K07321 cooC; CO dehydrogenase maturation factor D Mefer_0614 Cobyrinic acid ac-diamide synthase K07321 cooC; CO dehydrogenase maturation factor D Mefer_0914 Cobyrinic acid ac-diamide synthase K07321 cooC; CO dehydrogenase maturation factor C 99993 Cell motility D Mefer_1111 Protein of unknown function DUF439 K09156 cheF; taxis protein CheF C 99995 Signaling proteins D Mefer_1491 ACT domain-containing protein K07166 K07166; ACT domain-containing protein D Mefer_0274 tyrosine protein kinase K07176 K07176; putative serine/threonine protein kinase D Mefer_0610 DNA-binding TFAR19-related protein K06875 PDCD5; programmed cell death protein 5 C 99992 Structural proteins C 99994 Others D Mefer_1330 phosphate uptake regulator, PhoU K02039 phoU; phosphate transport system protein D Mefer_0909 phosphate uptake regulator, PhoU K02039 phoU; phosphate transport system protein D Mefer_0257 CutA1 divalent ion tolerance protein K03926 cutA; periplasmic divalent cation tolerance protein D Mefer_1067 hemerythrin-like metal-binding protein K07216 hr; hemerythrin D Mefer_1467 molybdenum cofactor synthesis domain protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] B B 09194 Poorly characterized C 99996 General function prediction only D Mefer_1534 PilT protein domain protein K06865 K06865; ATPase D Mefer_0317 ZPR1-like zinc finger protein K06874 K06874; zinc finger protein D Mefer_0539 DEAD/DEAH box helicase domain protein K06877 K06877; DEAD/DEAH box helicase domain-containing protein D Mefer_0183 HAD superfamily (subfamily IA) hydrolase, TIGR02253 K07025 K07025; putative hydrolase of the HAD superfamily D Mefer_0999 membrane-bound metal-dependent hydrolase K07038 K07038; inner membrane protein D Mefer_0293 TatD-related deoxyribonuclease K07049 K07049; TatD-related deoxyribonuclease D Mefer_1217 Sjogrens syndrome scleroderma autoantigen 1 K07143 K07143; UPF0148 protein D Mefer_0503 protein of unknown function DUF112 transmembrane K08971 K08971; putative membrane protein D Mefer_1254 Protein of unknown function DUF373 K08975 K08975; putative membrane protein C 99997 Function unknown D Mefer_0348 protein of unknown function DUF75 K06869 K06869; uncharacterized protein D Mefer_1416 serine protease-like protein K06870 K06870; uncharacterized protein D Mefer_1200 Radical SAM domain protein K06871 K06871; uncharacterized protein D Mefer_0755 metal dependent phosphohydrolase K06885 K06885; uncharacterized protein D Mefer_1029 protein of unknown function DUF201 K06913 K06913; uncharacterized protein D Mefer_0506 ATPase K06921 K06921; uncharacterized protein D Mefer_0251 ATPase K06921 K06921; uncharacterized protein D Mefer_0528 ATPase K06921 K06921; uncharacterized protein D Mefer_0913 ATPase K06921 K06921; uncharacterized protein D Mefer_0527 ATPase K06921 K06921; uncharacterized protein D Mefer_1321 ABC transporter, ATPase, predicted K06924 K06924; uncharacterized protein D Mefer_1183 nucleic acid binding OB-fold tRNA/helicase-type K06931 K06931; uncharacterized protein D Mefer_0378 protein of unknown function DUF134 K06933 K06933; uncharacterized protein D Mefer_0352 Radical SAM domain protein K06935 K06935; uncharacterized protein D Mefer_1170 Fe-S cluster domain protein K06939 K06939; uncharacterized protein D Mefer_0952 protein of unknown function UPF0153 K06940 K06940; uncharacterized protein D Mefer_0866 protein of unknown function UPF0153 K06940 K06940; uncharacterized protein D Mefer_0171 small GTP-binding protein K06945 K06945; uncharacterized protein D Mefer_1027 metal dependent phosphohydrolase K06950 K06950; uncharacterized protein D Mefer_0568 phosphoesterase K06953 K06953; uncharacterized protein D Mefer_0303 photosystem I assembly BtpA K06971 K06971; uncharacterized protein D Mefer_1192 Methyltransferase type 11 K06983 K06983; uncharacterized protein D Mefer_0708 deacetylase-like protein K06986 K06986; uncharacterized protein D Mefer_0553 exporter of the RND superfamily protein-like protein K07003 K07003; uncharacterized protein D Mefer_0643 pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 K07006; uncharacterized protein D Mefer_0869 4-vinyl reductase 4VR K07013 K07013; uncharacterized protein D Mefer_1116 4-vinyl reductase 4VR K07013 K07013; uncharacterized protein D Mefer_1065 4-vinyl reductase 4VR K07013 K07013; uncharacterized protein D Mefer_1320 hydrolase (metallo-beta-lactamase superfamily)-like protein K07022 K07022; uncharacterized protein D Mefer_1236 SufBD protein K07033 K07033; uncharacterized protein D Mefer_0383 KH-domain/beta-lactamase-domain protein K07041 K07041; uncharacterized protein D Mefer_0594 TatD-related deoxyribonuclease K07051 K07051; uncharacterized protein D Mefer_1486 protein of unknown function DUF35 K07068 K07068; uncharacterized protein D Mefer_1006 permease K07089 K07089; uncharacterized protein D Mefer_1368 permease K07089 K07089; uncharacterized protein D Mefer_0984 protein of unknown function DUF81 K07090 K07090; uncharacterized protein D Mefer_1036 DsrE family protein K07092 K07092; uncharacterized protein D Mefer_0863 phosphodiesterase, MJ0936 family K07095 K07095; uncharacterized protein D Mefer_1422 phosphodiesterase, MJ0936 family K07095 K07095; uncharacterized protein D Mefer_1388 metallophosphoesterase K07096 K07096; uncharacterized protein D Mefer_0655 conserved hypothetical protein K07112 K07112; uncharacterized protein D Mefer_0255 methanogenesis marker protein 2 K07123 K07123; uncharacterized protein D Mefer_1001 AIR synthase related protein domain protein K07123 K07123; uncharacterized protein D Mefer_1250 Radical SAM domain protein K07129 K07129; uncharacterized protein D Mefer_0172 Roadblock/LC7 family protein K07131 K07131; uncharacterized protein D Mefer_1480 ATPase K07133 K07133; uncharacterized protein D Mefer_1328 Queuosine synthesis-like protein K07134 K07134; uncharacterized protein D Mefer_1283 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K07137 K07137; uncharacterized protein D Mefer_0726 conserved hypothetical protein K07139 K07139; uncharacterized protein D Mefer_0659 PilT protein domain protein K07158 K07158; uncharacterized protein D Mefer_0275 protein of unknown function DUF75 K07159 K07159; uncharacterized protein D Mefer_0928 cysteine-rich small domain protein K07162 K07162; uncharacterized protein D Mefer_0894 protein of unknown function DUF192 K09005 K09005; uncharacterized protein D Mefer_0806 protein of unknown function DUF99 K09120 K09120; uncharacterized protein D Mefer_0709 Protein of unknown function DUF1867 K09126 K09126; uncharacterized protein D Mefer_0129 conserved hypothetical protein K09130 K09130; uncharacterized protein D Mefer_0210 protein of unknown function DUF167 K09131 K09131; uncharacterized protein D Mefer_0349 Protein of unknown function DUF473 K09135 K09135; uncharacterized protein D Mefer_0589 protein of unknown function DUF190 K09137 K09137; uncharacterized protein D Mefer_0712 protein of unknown function DUF364 K09138 K09138; uncharacterized protein D Mefer_1005 protein of unknown function DUF366 K09139 K09139; uncharacterized protein D Mefer_1175 AMMECR1 domain protein K09141 K09141; uncharacterized protein D Mefer_0167 protein of unknown function DUF369 K09143 K09143; uncharacterized protein D Mefer_0069 Protein of unknown function DUF1621 K09152 K09152; uncharacterized protein D Mefer_1019 protein of unknown function DUF447 K09154 K09154; uncharacterized protein D Mefer_0962 protein of unknown function DUF711 K09157 K09157; uncharacterized protein D Mefer_1459 protein of unknown function UPF0153 K09160 K09160; uncharacterized protein D Mefer_0634 metal dependent phosphohydrolase K09163 K09163; uncharacterized protein D Mefer_1528 protein of unknown function DUF1284 K09706 K09706; uncharacterized protein D Mefer_0613 Protein of unknown function UPF0146 K09713 K09713; uncharacterized protein D Mefer_1418 Protein of unknown function DUF504 K09715 K09715; uncharacterized protein D Mefer_1346 DNA polymerase beta domain protein region K09717 K09717; uncharacterized protein D Mefer_0192 Protein of unknown function DUF2226 K09718 K09718; uncharacterized protein D Mefer_0114 Protein of unknown function UPF0147 K09721 K09721; uncharacterized protein D Mefer_0306 Protein of unknown function DUF530 K09724 K09724; uncharacterized protein D Mefer_0457 Protein of unknown function DUF531 K09725 K09725; uncharacterized protein D Mefer_1405 protein of unknown function DUF354 K09726 K09726; uncharacterized protein D Mefer_0838 Protein of unknown function DUF356 K09727 K09727; uncharacterized protein D Mefer_0888 Protein of unknown function DUF357 K09728 K09728; uncharacterized protein D Mefer_0814 protein of unknown function DUF116 K09729 K09729; uncharacterized protein D Mefer_1322 Protein of unknown function UPF0179 K09730 K09730; uncharacterized protein D Mefer_0415 Protein of unknown function DUF555 K09731 K09731; uncharacterized protein D Mefer_1274 protein of unknown function DUF211 K09732 K09732; uncharacterized protein D Mefer_0550 Protein of unknown function DUF54 K09736 K09736; uncharacterized protein D Mefer_0582 Protein of unknown function DUF61 K09737 K09737; uncharacterized protein D Mefer_0473 Protein of unknown function DUF371 K09738 K09738; uncharacterized protein D Mefer_1525 ApbE family lipoprotein K09740 K09740; uncharacterized protein D Mefer_0701 Protein of unknown function DUF2067 K09742 K09742; uncharacterized protein D Mefer_1202 Protein of unknown function DUF1495 K09745 K09745; uncharacterized protein D Mefer_0545 protein of unknown function DUF343 K09791 K09791; uncharacterized protein D Mefer_1580 hypothetical protein K07502 yprB; uncharacterized protein D Mefer_1425 Putitive phosphate transport regulator K07220 K07220; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: April 24, 2024