+F Repair protein KO
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DNA Repair and Recombination Proteins - Ostreococcus tauri
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D OT_ostta08g02040 Helicase, C-terminal K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D OT_ostta03g05620 DNA photolyase, class 2 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D OT_ostta05g02360 DNA photolyase, class 2 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D OT_ostta13g01680 DNA photolyase, class 2 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E OT_ostta12g01670 Uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E OT_ostta14g02950 Helix-turn-helix, base-excision DNA repair,C-terminal K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E OT_ostta09g00180 DNA glycosylase K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
E OT_ostta11g00400 DNA glycosylase K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
E OT_ostta16g02045 Helix-turn-helix, base-excision DNA repair,C-terminal K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E OT_ostta15g02880 Endonuclease III-like, iron-sulphur cluster loop motif K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E OT_ostta14g00980 Helix-turn-helix, base-excision DNA repair,C-terminal K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E OT_ostta04g05210 Zinc finger, GRF-type K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F OT_ostta02g03430 DNA-directed DNA polymerase, family B, pol2 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F OT_ostta12g00110 DNA polymerase alpha/epsilon, subunit B K02328 POLD2; DNA polymerase delta subunit 2
F OT_ostta07g02610 DNA polymerase delta, subunit 4 K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F OT_ostta11g01840 DNA polymerase epsilon, catalytic subunit A,C-terminal K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F OT_ostta08g03680 DNA polymerase alpha/epsilon, subunit B K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F OT_ostta07g03460 Transcription factor CBF/NF-Y/archaeal histone K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
E OT_ostta06g02890 Proliferating cell nuclear antigen,PCNA,N-terminal K04802 PCNA; proliferating cell nuclear antigen
E OT_ostta08g02290 Helix-hairpin-helix motif, class 2 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E OT_ostta10g00640 DNA ligase, ATP-dependent, conserved site K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
E OT_ostta06g02740 Polynucleotide 3'-phosphatase K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E OT_ostta09g04280 DNA-directed DNA polymerase X K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F OT_ostta14g02480 DNA repair protein Rad4 K10838 XPC; xeroderma pigmentosum group C-complementing protein
F OT_ostta10g01910 UBA-like K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F OT_ostta02g00480 Zinc finger, RING-H2-type K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F OT_ostta04g00470 Cullin repeat-like-containing domain K10609 CUL4; cullin 4
F OT_ostta10g03360 Quinonprotein alcohol dehydrogenase-like superfamily K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
F OT_ostta13g02730 SNF2-related K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F OT_ostta10g01360 RNA polymerase II, heptapeptide repeat,eukaryotic K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F OT_ostta01g01720 RNA polymerase, beta subunit, conserved site K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F OT_ostta02g00880 DNA-directed RNA polymerase, 30-40kDa subunit,conserved site K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F OT_ostta09g00070 RNA polymerase II, Rpb4, core K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F OT_ostta04g04910 DNA-directed RNA polymerase RPB5 subunit,eukaryote/virus K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F OT_ostta02g00300 DNA-directed RNA polymerase, subunit K/Rpb6 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F OT_ostta10g01850 RNA polymerase Rpb7, N-terminal K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F OT_ostta10g01860 Nucleotide-binding, alpha-beta plait K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F OT_ostta10g01270 RNA polymerase, Rpb8 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F OT_ostta02g01770 DNA-directed RNA polymerase, subunit C11/M/9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F OT_ostta11g00380 RNA polymerases, subunit N, zinc binding site K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F OT_ostta07g01940 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F OT_ostta02g01780 RNA polymerase archaeal subunit P/eukaryotic subunit RPC10 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F OT_ostta02g00480 Zinc finger, RING-H2-type K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F OT_ostta04g00470 Cullin repeat-like-containing domain K10609 CUL4; cullin 4
F OT_ostta10g03360 Quinonprotein alcohol dehydrogenase-like superfamily K10610 DDB1; DNA damage-binding protein 1
F OT_ostta11g01320 WD40 repeat K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F OT_ostta02g03670 SNF2-related K10841 ERCC6; DNA excision repair protein ERCC-6
F OT_ostta01g02380 Transcription elongation factor 1 K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E OT_ostta03g04230 Helicase, C-terminal K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E OT_ostta12g02900 P-loop containing nucleoside triphosphate hydrolase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E OT_ostta17g00850 BSD K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E OT_ostta06g02150 von Willebrand factor, type A K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E OT_ostta01g02120 TFIIH subunit Tfb4/p34 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E OT_ostta02g01170 Transcription factor TFIIH subunit p52/Tfb2 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E OT_ostta15g01360 TFIIH subunit TTDA/Tfb5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E OT_ostta07g01400 Serine/threonine-protein kinase, active site K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E OT_ostta03g02270 Cyclin C K06634 CCNH; cyclin H
E OT_ostta11g01960 Cdk-activating kinase assembly factor MAT1,centre K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E OT_ostta15g01090 Replication factor-A protein 1, N-terminal K07466 RFA1; replication factor A1
E OT_ostta18g01440 Replication factor A, C-terminal K07466 RFA1; replication factor A1
E OT_ostta13g01140 Replication protein A, C-terminal K10739 RFA2; replication factor A2
E OT_ostta07g02710 Nucleic acid-binding, OB-fold K10740 RPA3; replication factor A3
D Other NER factors
E OT_ostta18g00180 Restriction endonuclease type II-like K10849 ERCC1; DNA excision repair protein ERCC-1
E OT_ostta08g01210 Restriction endonuclease type II-like K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E OT_ostta10g00640 DNA ligase, ATP-dependent, conserved site K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E OT_ostta14g02810 RNAPII transcription regulator C-terminal K15075 MET18; DNA repair/transcription protein MET18/MMS19
E OT_ostta03g02790 Cullin repeat-like-containing domain K03869 CUL3; cullin 3
E OT_ostta12g01180 SKP1 component, POZ domain K03872 ELOC; elongin-C
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E OT_ostta10g02100 DNA mismatch repair protein, MSH2 K08735 MSH2; DNA mismatch repair protein MSH2
E OT_ostta04g02050 DNA mismatch repair protein MutS-like,N-terminal K08736 MSH3; DNA mismatch repair protein MSH3
E OT_ostta06g02640 DNA mismatch repair protein MutS-homologue MSH6 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E OT_ostta13g02280 Ribosomal protein S5 domain 2-type fold,subgroup K08734 MLH1; DNA mismatch repair protein MLH1
E OT_ostta06g03990 DNA mismatch repair protein Pms1/Mlh2 K10858 PMS2; DNA mismatch repair protein PMS2
D DNA polymerase delta complex
E OT_ostta02g03430 DNA-directed DNA polymerase, family B, pol2 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E OT_ostta12g00110 DNA polymerase alpha/epsilon, subunit B K02328 POLD2; DNA polymerase delta subunit 2
E OT_ostta07g02610 DNA polymerase delta, subunit 4 K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E OT_ostta15g01090 Replication factor-A protein 1, N-terminal K07466 RFA1; replication factor A1
E OT_ostta18g01440 Replication factor A, C-terminal K07466 RFA1; replication factor A1
E OT_ostta13g01140 Replication protein A, C-terminal K10739 RFA2; replication factor A2
E OT_ostta07g02710 Nucleic acid-binding, OB-fold K10740 RPA3; replication factor A3
D RFC (replication factor C)
E OT_ostta02g00500 P-loop containing nucleoside triphosphate hydrolase K10754 RFC1; replication factor C subunit 1
E OT_ostta09g00990 P-loop containing nucleoside triphosphate hydrolase K10755 RFC2_4; replication factor C subunit 2/4
E OT_ostta12g02485 P-loop containing nucleoside triphosphate hydrolase K10755 RFC2_4; replication factor C subunit 2/4
E OT_ostta05g00150 P-loop containing nucleoside triphosphate hydrolase K10756 RFC3_5; replication factor C subunit 3/5
E OT_ostta02g00555 P-loop containing nucleoside triphosphate hydrolase K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E OT_ostta06g02890 Proliferating cell nuclear antigen,PCNA,N-terminal K04802 PCNA; proliferating cell nuclear antigen
E OT_ostta01g04740 Helix-hairpin-helix motif, class 2 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E OT_ostta16g01750 5'-3' exonuclease, C-terminal domain K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E OT_ostta10g00640 DNA ligase, ATP-dependent, conserved site K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E OT_ostta08g03730 WD40 repeat K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E OT_ostta07g00020 Mre11, DNA-binding K10865 MRE11; double-strand break repair protein MRE11
D BRCA1-core complex
E OT_ostta05g00310 Breast cancer type 1 susceptibility protein (BRCA1) K10683 BARD1; BRCA1-associated RING domain protein 1
D BRCA1-A complex
D BRCA1-B complex
E OT_ostta04g00700 DEAD2 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E OT_ostta08g00240 ATP-dependent helicase, C-terminal K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E OT_ostta07g02540 BRCT domain K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
E OT_ostta04g01710 BRCT domain K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D BRCA1-C complex
E OT_ostta07g00020 Mre11, DNA-binding K10865 MRE11; double-strand break repair protein MRE11
D BRCA complex
E OT_ostta11g00630 Breast cancer type 2 susceptibility protein K08775 BRCA2; breast cancer 2 susceptibility protein
E OT_ostta08g01800 DNA recombination/repair protein RecA,monomer-monomer interface K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E OT_ostta08g01800 DNA recombination/repair protein RecA,monomer-monomer interface K04482 RAD51; DNA repair protein RAD51
E OT_ostta09g03555 DNA recombination and repair protein Rad51,C-terminal K10869 RAD51L1; RAD51-like protein 1
E OT_ostta12g02080 DNA recombination and repair protein Rad51,C-terminal K10870 RAD51L2; RAD51-like protein 2
E OT_ostta12g01520 DNA recombination and repair protein Rad51,C-terminal K10871 RAD51L3; RAD51-like protein 3
E OT_ostta03g05010 DNA recombination and repair protein Rad51,C-terminal K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
D Rad54 family proteins
E OT_ostta08g03990 SNF2-related K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E OT_ostta09g03530 SNF2-related K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E OT_ostta04g00480 DNA/RNA helicase, DEAD/DEAH box type, N-terminal K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E OT_ostta03g01680 Helicase, C-terminal K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E OT_ostta05g04200 Helicase, C-terminal K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E OT_ostta03g01680 Helicase, C-terminal K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E OT_ostta03g04030 Zinc finger, CCHC-type K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E OT_ostta06g03325 DNA topoisomerase, type IA, central region,subdomain 2 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D RPA (replication factor A)
E OT_ostta15g01090 Replication factor-A protein 1, N-terminal K07466 RFA1; replication factor A1
E OT_ostta18g01440 Replication factor A, C-terminal K07466 RFA1; replication factor A1
E OT_ostta13g01140 Replication protein A, C-terminal K10739 RFA2; replication factor A2
E OT_ostta07g02710 Nucleic acid-binding, OB-fold K10740 RPA3; replication factor A3
D Protein phosphatase 4
E OT_ostta04g03670 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E OT_ostta04g01320 Armadillo-type fold K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E OT_ostta15g02130 Domain of unknown function DUF625 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E OT_ostta01g06330 RecF/RecN/SMC, N-terminal K22803 SMC5; structural maintenance of chromosomes protein 5
E OT_ostta07g02570 Structural maintenance of chromosomes protein 6 K22804 SMC6; structural maintenance of chromosomes protein 6
E OT_ostta07g02660 Non-structural maintenance of chromosomes element 1 K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E OT_ostta18g00610 unnamed product K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E OT_ostta01g01050 Non-structural maintenance of chromosome element 4, C-terminal K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E OT_ostta03g05810 DNA repair nuclease, XPF-type/Helicase K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E OT_ostta06g01000 DSS1/SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E OT_ostta16g00515 GIY-YIG nuclease superfamily K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E OT_ostta01g00730 HD/PDEase domain K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E OT_ostta15g01790 P-loop containing nucleoside triphosphate hydrolase K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E OT_ostta15g01810 P-loop containing nucleoside triphosphate hydrolase K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E OT_ostta04g04320 Zinc finger, SWIM-type K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E OT_ostta08g03530 von Willebrand factor, type A K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E OT_ostta07g04750 von Willebrand factor, type A K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
E OT_ostta12g01960 Phosphatidylinositol 3/4-kinase, conserved site K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D MRX complex
E OT_ostta07g00020 Mre11, DNA-binding K10865 MRE11; double-strand break repair protein MRE11
D DNA Ligase 4 complex
E OT_ostta11g01600 DNA ligase, ATP-dependent, N-terminal K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
E OT_ostta09g04280 DNA-directed DNA polymerase X K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E OT_ostta07g00840 Endonuclease/exonuclease/phosphatase K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E OT_ostta05g03920 JmjC domain K25792 JMJD8; jumonji domain-containing protein 8
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
E OT_ostta16g02685 unnamed product K11511 APITD1; centromere protein S
E OT_ostta05g00510 Centromere protein X K15360 STRA13; centromere protein X
D Bloom's syndrome complex (BTR)
E OT_ostta03g01680 Helicase, C-terminal K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E OT_ostta03g04030 Zinc finger, CCHC-type K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E OT_ostta06g03325 DNA topoisomerase, type IA, central region,subdomain 2 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D FANCD2-I complex
D Downstream FA components
E OT_ostta11g00630 Breast cancer type 2 susceptibility protein K08775 BRCA2; breast cancer 2 susceptibility protein
E OT_ostta04g00700 DEAD2 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E OT_ostta08g00240 ATP-dependent helicase, C-terminal K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D Other FA pathway factors
E OT_ostta08g01800 DNA recombination/repair protein RecA,monomer-monomer interface K04482 RAD51; DNA repair protein RAD51
E OT_ostta12g02080 DNA recombination and repair protein Rad51,C-terminal K10870 RAD51L2; RAD51-like protein 2
E OT_ostta04g04920 unnamed product K11137 TELO2; telomere length regulation protein
E OT_ostta15g00950 G-protein beta WD-40 repeat K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E OT_ostta18g01110 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
D Ubiquitin ligases
D Others
E OT_ostta08g00740 WD40/YVTN repeat-like-containing domain K23314 WRAP53; telomerase Cajal body protein 1
E OT_ostta08g01670 WD40 repeat K24752 WDR70; WD repeat-containing protein 70
E OT_ostta08g03730 WD40 repeat K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D OT_ostta11g01690 DNA-repair protein, UmuC-like, N-terminal K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D OT_ostta07g01380 DNA-repair protein, UmuC-like, N-terminal K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D OT_ostta10g00650 DNA-repair protein, UmuC-like, N-terminal K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
D OT_ostta14g02945 Ubiquitin-conjugating enzyme, active site K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D OT_ostta01g03130 Zinc finger, RING/FYVE/PHD-type K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D OT_ostta09g03940 Ubiquitin-conjugating enzyme, E2 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D OT_ostta05g02510 Ubiquitin-conjugating enzyme, E2 K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D OT_ostta06g02890 Proliferating cell nuclear antigen,PCNA,N-terminal K04802 PCNA; proliferating cell nuclear antigen
D OT_ostta01g03870 Domain of unknown function SprT-like K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D OT_ostta10g02080 Rad9 K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D OT_ostta05g04190 Checkpoint protein Hus1/Mec3 K10903 HUS1; HUS1 checkpoint protein
D OT_ostta09g02470 Rad1/Rec1/Rad17 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D OT_ostta05g00180 P-loop containing nucleoside triphosphate hydrolase K06662 HRAD17; cell cycle checkpoint protein
D OT_ostta09g00990 P-loop containing nucleoside triphosphate hydrolase K10755 RFC2_4; replication factor C subunit 2/4
D OT_ostta12g02485 P-loop containing nucleoside triphosphate hydrolase K10755 RFC2_4; replication factor C subunit 2/4
D OT_ostta05g00150 P-loop containing nucleoside triphosphate hydrolase K10756 RFC3_5; replication factor C subunit 3/5
D OT_ostta02g00555 P-loop containing nucleoside triphosphate hydrolase K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D OT_ostta09g02470 Rad1/Rec1/Rad17 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D OT_ostta02g02210 Timeless protein K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D OT_ostta04g04970 Zinc finger, CCHC-type K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
C Triple T complex
D OT_ostta04g04920 unnamed product K11137 TELO2; telomere length regulation protein
D OT_ostta10g00140 Armadillo-type fold K20403 TTI1; TELO2-interacting protein 1
D OT_ostta12g01330 unnamed product K23115 TTI2; TELO2-interacting protein 2
C BAG6-UBL4A-GET4 complex
C Other check point factors
D OT_ostta07g03510 PIK-related kinase, FATC K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D OT_ostta12g01965 PIK-related kinase, FATC K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D OT_ostta08g00755 hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon
D OT_ostta18g00920 14-3-3 protein, conserved site K06630 YWHAE; 14-3-3 protein epsilon
D OT_ostta10g02790 Serine/threonine-protein kinase, active site K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D OT_ostta03g00330 Donson K22422 DONSON; protein downstream neighbor of Son
D OT_ostta10g00630 MIT K12196 VPS4; vacuolar protein-sorting-associated protein 4
B Other factors with a suspected DNA repair function
C DNA polymerases
D OT_ostta09g03880 Helicase, C-terminal K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
D OT_ostta04g04050 Armadillo-type fold K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
D OT_ostta10g00310 DNA primase, UL52/UL70 type, Herpesviridae K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Nucleases
D OT_ostta11g02230 DNA repair metallo-beta-lactamase K15340 DCLRE1A; DNA cross-link repair 1A protein
D OT_ostta11g00290 DNA repair metallo-beta-lactamase K15340 DCLRE1A; DNA cross-link repair 1A protein
D OT_ostta06g04050 Beta-lactamase-like K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
C Helicases
C PSO4 complex
D OT_ostta03g01670 WD40/YVTN repeat-like-containing domain K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D OT_ostta05g00460 Domain of unknown function DUF3351 K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D OT_ostta08g02120 G-protein beta WD-40 repeat K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D OT_ostta09g02490 NUDIX hydrolase, conserved site K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D OT_ostta17g02305 DeoxyUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D OT_ostta01g00090 Ribonucleotide reductase R1 subunit, N-terminal K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D OT_ostta12g01230 Ferritin-like superfamily K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D OT_ostta08g00560 Ferritin-like superfamily K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D OT_ostta03g05620 DNA photolyase, class 2 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D OT_ostta05g02360 DNA photolyase, class 2 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D OT_ostta13g01680 DNA photolyase, class 2 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E OT_ostta12g01670 Uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E OT_ostta14g02950 Helix-turn-helix, base-excision DNA repair,C-terminal K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E OT_ostta12g00655 DNA glycosylase/AP lyase, H2TH DNA-binding K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E OT_ostta15g02880 Endonuclease III-like, iron-sulphur cluster loop motif K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E OT_ostta14g00980 Helix-turn-helix, base-excision DNA repair,C-terminal K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E OT_ostta18g00830 Exodeoxyribonuclease III xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
D DNA ligase
D DNA polymerase I
E OT_ostta09g02790 3'-5' exonuclease domain K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E OT_ostta09g02790 3'-5' exonuclease domain K02335 polA; DNA polymerase I [EC:2.7.7.7]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F OstapCp26 rpoB; RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F OstapCp27 RpoC1; RNA polymerase beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F OstapCp28 RpoC2; RpoC2 K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F OstapCp42 RpoA; RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E OT_ostta10g02820 P-loop containing nucleoside triphosphate hydrolase K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
E OT_ostta20g00860 P-loop containing nucleoside triphosphate hydrolase K04485 radA; DNA repair protein RadA/Sms
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F OT_ostta03g01780 DNA topoisomerase, type IIA, conserved site K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D OT_ostta09g02490 NUDIX hydrolase, conserved site K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D OT_ostta17g02305 DeoxyUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024