+E Ubiquitin system KO
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Ubiquitin System - Plasmodium falciparum 3D7
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C PF3D7_1211800 polyubiquitin K08770 UBC; ubiquitin C
C PF3D7_1365900 ubiquitin-60S ribosomal protein L40 K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C PF3D7_1402500 ribosomal protein S27a, putative K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C PF3D7_0219200 40S ribosomal protein S30 K02983 RP-S30e; small subunit ribosomal protein S30e
C PF3D7_1019900 autophagy-related protein 8 K08341 GABARAP; GABA(A) receptor-associated protein
C PF3D7_1470000 autophagy-related protein 12, putative K08336 ATG12; ubiquitin-like protein ATG12
C PF3D7_1138100 ubiquitin-related modifier 1, putative K12161 URM1; ubiquitin related modifier 1
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C PF3D7_1225800 ubiquitin-activating enzyme E1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C PF3D7_1144500 SUMO-activating enzyme subunit 1 K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C PF3D7_1237000 SUMO-activating enzyme subunit 2 K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C PF3D7_0817000 NEDD8-activating enzyme E1 catalytic subunit, putative K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C PF3D7_1365400 ubiquitin-activating enzyme K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C PF3D7_0812600 ubiquitin-conjugating enzyme E2, putative K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C PF3D7_0319300 ubiquitin-conjugating enzyme E2, putative K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
C PF3D7_1203900 ubiquitin-conjugating enzyme E2 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C PF3D7_0921000.1 ubiquitin-conjugating enzyme E2, putative K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C PF3D7_1033900 ubiquitin-conjugating enzyme E2, putative K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C PF3D7_1356300 ubiquitin-conjugating enzyme E2, putative K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C PF3D7_0527100 ubiquitin-conjugating enzyme E2 N, putative K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C PF3D7_1412900.1 ubiquitin-conjugating enzyme E2, putative K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C PF3D7_0606200 ubiquitin-conjugating enzyme E2 PEX4, putative K10689 PEX4; peroxin-4 [EC:2.3.2.23]
B UBL-conjugating enzymes
C PF3D7_0915100 SUMO-conjugating enzyme UBC9 K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C PF3D7_1245300 NEDD8-conjugating enzyme UBC12, putative K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C PF3D7_0905700.1 autophagy-related protein 3, putative K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
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AUbiquitin ligases (E3)
B HECT type E3
C HECT type E3 associated proteins
B U-box type E3
C PF3D7_0707700 E3 ubiquitin-protein ligase, putative K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C PF3D7_0930600.1 peptidyl-prolyl cis-trans isomerase K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C PF3D7_0308600 pre-mRNA-processing factor 19, putative K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
B Single Ring-finger type E3
C BRE1 proteins
C CBL proteins
C SINA (Seven in absentia) proteins
C Ligand of Numb proteins
C March proteins
C MDM2/MDM4 proteins
C NFX1 proteins
C Pellino proteins
C Peripheral membrane proteins
C RBR proteins
C TRAF proteins
C TRIM/RBCC proteins
C UBR box proteins
C ATL proteins
C Other single Ring-finger type E3
D PF3D7_0209700 RING zinc finger protein, putative K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D PF3D7_0323700 U4/U6.U5 tri-snRNP-associated protein 1, putative K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D PF3D7_1422500 ERAD-associated E3 ubiquitin-protein ligase HRD1 K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D PF3D7_0312100 E3 ubiquitin-protein ligase K23788 TUL1; transmembrane E3 ubiquitin-protein ligase [EC:2.3.2.27]
B Atypical E3
B UBL E3 ligases
C PF3D7_0319100 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E PF3D7_0319100 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E PF3D7_0811000 cullin-1, putative K03347 CUL1; cullin 1
D Adaptor protein
E PF3D7_1367000 suppressor of kinetochore protein 1, putative K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
C Cul2 complex
D Ring finger protein
E PF3D7_0319100 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adoptor protein
D Target recognizing subunit
C Cul3 complex
D Ring finger protein
E PF3D7_0319100 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adoptor and target recognizing subunit (BTB)
C Cul4 complex
D Ring finger protein
E PF3D7_0319100 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adoptor protein
D Target recognizing subunit (DCAF)
E PF3D7_0409200 protein SOF1, putative K11806 DCAF13; DDB1- and CUL4-associated factor 13
E PF3D7_0518600 WD repeat-containing protein 26, putative K22382 WDR26; WD repeat-containing protein 26
E PF3D7_1033500 WD repeat-containing protein 70, putative K24752 WDR70; WD repeat-containing protein 70
C Cul5 complex
D Ring finger protein
D Cullin
D Adoptor protein
D Target recognizing subunit
C Cul7 complex
D Ring finger protein
E PF3D7_0319100 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E PF3D7_1367000 suppressor of kinetochore protein 1, putative K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E PF3D7_0319100 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E PF3D7_0319100 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
E PF3D7_0624500 anaphase-promoting complex subunit 11, putative K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
D Target recognizing subunit
E PF3D7_1026400 cell division cycle protein 20 homolog, putative K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E PF3D7_1217600 anaphase-promoting complex subunit 10, putative K03357 APC10; anaphase-promoting complex subunit 10
C BRCC complex
D PF3D7_1107400 DNA repair protein RAD51 K04482 RAD51; DNA repair protein RAD51
C KPC complex
C LUBAC complex
C CTLH complex
D PF3D7_1330500 CTLH domain-containing protein, putative K18624 MAEA; macrophage erythroblast attacher
D PF3D7_1336400 RanBPM and CLTH-like protein, putative K23338 GID8; glucose-induced degradation protein 8
D PF3D7_0518600 WD repeat-containing protein 26, putative K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
C LMBR1L-GP78-UBAC2 complex
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
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ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D PF3D7_1460400 ubiquitin carboxyl-terminal hydrolase isozyme L3 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D PF3D7_1117100 ubiquitin carboxyl-terminal hydrolase UCH54 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D PF3D7_0403500 ubiquitin specific protease, putative K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D PF3D7_0516700 ubiquitin carboxyl-terminal hydrolase 2, putative K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D PF3D7_0413900 ubiquitin carboxyl-terminal hydrolase 13, putative K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D PF3D7_0726500 ubiquitin carboxyl-terminal hydrolase, putative K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D PF3D7_0527200 ubiquitin carboxyl-terminal hydrolase 14 K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
C OTU
C MJD
D PF3D7_1226800 ataxin-3, putative K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D PF3D7_1111900 Josephin domain-containing protein, putative K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D PF3D7_1319100 ubiquitin carboxyl-terminal hydrolase MINDY, putative K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
C JAMM
D PF3D7_1368100 26S proteasome regulatory subunit RPN11, putative K03030 PSMD14; 26S proteasome regulatory subunit N11
C PPPDE
D PF3D7_1006900 PPPDE peptidase, putative K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
C BRISC complex
B UBL-specific proteases (ULPs)
C PF3D7_1233900 SUMO-specific protease 1 K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C PF3D7_1460400 ubiquitin carboxyl-terminal hydrolase isozyme L3 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C PF3D7_1217900 uncharacterized protein K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C COP9 signalosome (CSN) complex
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 1, 2024