+F Repair protein KO
#
DNA Repair and Recombination Proteins - Pseudomonas fluorescens A506
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D PflA506_1380 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D PflA506_0738 phrB; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E PflA506_1387 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E PflA506_4720 DNA-3-methyladenine glycosylase, putative K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E PflA506_0310 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E PflA506_1126 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E PflA506_2628 DEAD 2 domain protein K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D PflA506_2435 hydrolase, NUDIX family K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PflA506_4239 mutator mutT protein/thiamine monophosphate synthase (TenI) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PflA506_1085 hydrolase, NUDIX family K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PflA506_5267 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D PflA506_1380 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D PflA506_2747 ada; ADA regulatory protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D PflA506_0738 phrB; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D PflA506_2746 alkB; alkylated DNA repair protein AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E PflA506_1387 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E PflA506_2256 mug; G/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E PflA506_4188 alkA; DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E PflA506_4720 DNA-3-methyladenine glycosylase, putative K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E PflA506_0310 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E PflA506_0011 tag_3; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E PflA506_2527 tag_1; DNA-3-methyladenine glycosylase 1 K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E PflA506_5090 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E PflA506_1126 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E PflA506_3253 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E PflA506_5271 exodeoxyribonuclease III, putative K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E PflA506_4306 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E PflA506_3888 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E PflA506_5006 ligA; NAD-dependent DNA ligase adenylation domain protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E PflA506_0078 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E PflA506_4794 uvrA_2; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E PflA506_2365 uvrA_1; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E PflA506_3521 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E PflA506_2156 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E PflA506_5379 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PflA506_0078 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E PflA506_3888 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E PflA506_5006 ligA; NAD-dependent DNA ligase adenylation domain protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F PflA506_4829 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F PflA506_4828 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F PflA506_4798 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F PflA506_5276 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F PflA506_1579 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E PflA506_1132 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E PflA506_0504 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E PflA506_4250 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E PflA506_4355 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E PflA506_4756 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E PflA506_1247 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E PflA506_0002 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E PflA506_1037 holC; DNA polymerase III, chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E PflA506_4704 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E PflA506_4006 holB; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E PflA506_2454 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E PflA506_4668 exonuclease family protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E PflA506_4929 exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E PflA506_3880 dnaX; DNA polymerase III, gamma and tau subunit K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E PflA506_3888 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E PflA506_5006 ligA; NAD-dependent DNA ligase adenylation domain protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E PflA506_5379 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PflA506_4792 ssb_1; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E PflA506_p0062 ssb_2; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E PflA506_1646 D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E PflA506_4501 recB; exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E PflA506_4502 recC; exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E PflA506_4500 recD; exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E PflA506_1162 recA; RecA protein K03553 recA; recombination protein RecA
E PflA506_4223 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E PflA506_4222 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E PflA506_4224 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E PflA506_0394 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E PflA506_4250 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E PflA506_2512 sbcC; exonuclease SbcCD, C subunit K03546 sbcC; DNA repair protein SbcC/Rad50
E PflA506_2513 sbcD; exonuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E PflA506_1162 recA; RecA protein K03553 recA; recombination protein RecA
E PflA506_4631 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E PflA506_0003 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E PflA506_5285 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E PflA506_4306 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E PflA506_1045 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E PflA506_3877 recR; recombination protein RecR K06187 recR; recombination protein RecR
E PflA506_4566 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E PflA506_1915 recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E PflA506_4223 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E PflA506_4222 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E PflA506_4224 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E PflA506_2512 sbcC; exonuclease SbcCD, C subunit K03546 sbcC; DNA repair protein SbcC/Rad50
E PflA506_2513 sbcD; exonuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
E PflA506_4243 protein of unknown function, DUF853 family K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E PflA506_2575 Ku protein K10979 ku; DNA end-binding protein Ku
E PflA506_1430 ligD_2; DNA ligase D K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E PflA506_2574 ligD_1; DNA ligase D K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F PflA506_1695 gyrA; DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F PflA506_0004 gyrB; DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F PflA506_1570 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F PflA506_2752 DNA topoisomerase I, putative K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F PflA506_5314 hupA; DNA-binding protein HU, alpha subunit K05787 hupA; DNA-binding protein HU-alpha
F PflA506_3298 hupB; DNA-binding protein HU, beta subunit K03530 hupB; DNA-binding protein HU-beta
F PflA506_1033 hupN; DNA-binding protein HU, nu subunit K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F PflA506_4306 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F PflA506_1045 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F PflA506_3877 recR; recombination protein RecR K06187 recR; recombination protein RecR
F PflA506_3888 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F PflA506_5006 ligA; NAD-dependent DNA ligase adenylation domain protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F PflA506_0593 fis; DNA-binding protein Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F PflA506_3451 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
F PflA506_1703 ihfB; integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
E Supressor
F PflA506_4250 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F PflA506_0273 ATP-dependent DNA helicase, RecQ family K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F PflA506_3773 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F PflA506_4794 uvrA_2; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F PflA506_2365 uvrA_1; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F PflA506_3521 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D PflA506_4301 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D PflA506_p0004 rulB; ultraviolet light resistance protein RulB K03502 umuC; DNA polymerase V
D PflA506_p0003 rulA; ultraviolet light resistance protein RulA K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D PflA506_1162 recA; RecA protein K03553 recA; recombination protein RecA
D PflA506_1574 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D PflA506_2360 lexA2; LexA repressor, putative K01356 lexA; repressor LexA [EC:3.4.21.88]
D PflA506_4566 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D PflA506_1968 polB; DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D PflA506_2361 hypothetical protein K14160 imuA; protein ImuA
D PflA506_2362 hypothetical protein K14161 imuB; protein ImuB
D PflA506_2363 dnaE2; DNA polymerase III, alpha subunit K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D PflA506_4792 ssb_1; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D PflA506_p0062 ssb_2; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D PflA506_1163 recX; regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D PflA506_5245 rep; ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D PflA506_1283 dinG; ATP-dependent helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D PflA506_4781 lhr; ATP-dependent helicase, putative K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D PflA506_1269 DEAD/DEAH box helicase domain protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D PflA506_2435 hydrolase, NUDIX family K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PflA506_4239 mutator mutT protein/thiamine monophosphate synthase (TenI) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PflA506_1085 hydrolase, NUDIX family K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PflA506_5267 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D PflA506_4032 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D PflA506_2912 ribonucleoside-diphosphate reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D PflA506_4083 ribonucleoside-diphosphate reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024