+D Receptor KO
#
G Protein-Coupled Receptors - Pseudopodoces humilis (Tibetan ground-tit)
%
!
ARhodopsin family
B Biogenic amine
C Acetylcholine (muscarinic)
D 102103691 CHRM2; muscarinic acetylcholine receptor M2 isoform X2 K04130 CHRM2; muscarinic acetylcholine receptor M2
D 102110816 CHRM3; muscarinic acetylcholine receptor M3 K04131 CHRM3; muscarinic acetylcholine receptor M3
D 102100125 CHRM4; muscarinic acetylcholine receptor M4 K04132 CHRM4; muscarinic acetylcholine receptor M4
D 102103122 CHRM5; muscarinic acetylcholine receptor M5 K04133 CHRM5; muscarinic acetylcholine receptor M5
C Adrenaline
D 102108110 ADRA1A; alpha-1A adrenergic receptor K04135 ADRA1A; adrenergic receptor alpha-1A
D 102105127 ADRA1B; alpha-1B adrenergic receptor K04136 ADRA1B; adrenergic receptor alpha-1B
D 102104078 ADRA1D; alpha-1D adrenergic receptor K04137 ADRA1D; adrenergic receptor alpha-1D
D 102109587 ADRA2A; alpha-2A adrenergic receptor K04138 ADRA2A; adrenergic receptor alpha-2A
D 102111432 ADRA2C; alpha-2C adrenergic receptor K04140 ADRA2C; adrenergic receptor alpha-2C
D 102102017 alpha-2Db adrenergic receptor-like K04140 ADRA2C; adrenergic receptor alpha-2C
D 102113245 ADRB1; beta-1 adrenergic receptor K04141 ADRB1; adrenergic receptor beta-1
D 102102944 ADRB2; beta-2 adrenergic receptor K04142 ADRB2; adrenergic receptor beta-2
D 102111297 ADRB3; beta-3 adrenergic receptor K04143 ADRB3; adrenergic receptor beta-3
C Dopamine
D 102111882 DRD1; D(1A) dopamine receptor K04144 DRD1; dopamine receptor D1
D 102106330 DRD2; D(2) dopamine receptor isoform X1 K04145 DRD2; dopamine receptor D2
D 102110328 DRD3; D(3) dopamine receptor K04146 DRD3; dopamine receptor D3
D 102106131 DRD4; D(4) dopamine receptor K04147 DRD4; dopamine receptor D4
D 102109760 DRD5; D(1B) dopamine receptor K05840 DRD5; dopamine receptor D5
D 102112671 D(1) dopamine receptor-like K05840 DRD5; dopamine receptor D5
D 102101295 D(1) dopamine receptor-like K05840 DRD5; dopamine receptor D5
C Dopamine and ecdysteroid
C Histamine
D 102105211 HRH1; histamine H1 receptor K04149 HRH1; histamine receptor H1
D 102100003 histamine H2 receptor-like K04150 HRH2; histamine receptor H2
D 102099071 probable G-protein coupled receptor No9 K04150 HRH2; histamine receptor H2
D 102099817 histamine H2 receptor-like K04150 HRH2; histamine receptor H2
D 102107583 histamine H3 receptor-like K04151 HRH3; histamine receptor H3
D 102107760 histamine H3 receptor-like K04151 HRH3; histamine receptor H3
D 102112817 histamine H3 receptor-like K04151 HRH3; histamine receptor H3
D 102108815 HRH3; histamine H3 receptor K04151 HRH3; histamine receptor H3
C Octopamine and tryamine
C Serotonin
D 102113168 HTR1B; 5-hydroxytryptamine receptor 1B K04153 HTR1; 5-hydroxytryptamine receptor 1
D 102102298 HTR1E; 5-hydroxytryptamine receptor 1E K04153 HTR1; 5-hydroxytryptamine receptor 1
D 102103881 HTR1A; 5-hydroxytryptamine receptor 1A K04153 HTR1; 5-hydroxytryptamine receptor 1
D 102108773 HTR1D; 5-hydroxytryptamine receptor 1D K04153 HTR1; 5-hydroxytryptamine receptor 1
D 102102375 HTR1F; 5-hydroxytryptamine receptor 1F K04153 HTR1; 5-hydroxytryptamine receptor 1
D 102106216 HTR2A; 5-hydroxytryptamine receptor 2A isoform X1 K04157 HTR2; 5-hydroxytryptamine receptor 2
D 102100868 HTR2C; 5-hydroxytryptamine receptor 2C isoform X1 K04157 HTR2; 5-hydroxytryptamine receptor 2
D 102101838 HTR2B; 5-hydroxytryptamine receptor 2B K04157 HTR2; 5-hydroxytryptamine receptor 2
D 102104944 HTR4; 5-hydroxytryptamine receptor 4 K04160 HTR4; 5-hydroxytryptamine receptor 4
D 102113052 5-hydroxytryptamine receptor 5B-like K04161 HTR5; 5-hydroxytryptamine receptor 5
D 102114614 HTR5A; 5-hydroxytryptamine receptor 5A K04161 HTR5; 5-hydroxytryptamine receptor 5
D 102102205 HTR6; 5-hydroxytryptamine receptor 6 K04162 HTR6; 5-hydroxytryptamine receptor 6
D 102106600 5-hydroxytryptamine receptor 7-like K04163 HTR7; 5-hydroxytryptamine receptor 7
D 102103601 HTR7; 5-hydroxytryptamine receptor 7 K04163 HTR7; 5-hydroxytryptamine receptor 7
C Trace amine
D 102102003 TAAR2; LOW QUALITY PROTEIN: trace amine-associated receptor 2 K05051 TAAR; trace amine associated receptor
D 102100282 TAAR1; trace amine-associated receptor 1 K05051 TAAR; trace amine associated receptor
B Peptide
C Adrenomedullin (G10D)
C Adropin
D 102099228 GPR19; probable G-protein coupled receptor 19 K04316 GPR19; G protein-coupled receptor 19
D 102104977 probable G-protein coupled receptor 19 K04316 GPR19; G protein-coupled receptor 19
C Apelin
D 102113141 APLNR; apelin receptor K04174 APLNR; apelin receptor
C Anaphylatoxin
D 102101481 C3AR1; C3a anaphylatoxin chemotactic receptor K04009 C3AR1; C3a anaphylatoxin chemotactic receptor
D 102111852 C5a anaphylatoxin chemotactic receptor 1-like K04010 C5AR1; C5a anaphylatoxin chemotactic receptor 1
C Angiotensin
D 102112440 AGTR1; type-1 angiotensin II receptor K04166 AGTR1; angiotensin II receptor type 1
D 102108224 AGTR2; type-2 angiotensin II receptor K04167 AGTR2; angiotensin II receptor type 2
C BigLEN
C Bombesin
D 102104563 NMBR; neuromedin-B receptor K04168 NMBR; neuromedin B receptor
D 102109279 GRPR; gastrin-releasing peptide receptor K04169 GRPR; gastrin-releasing peptide receptor
D 102107182 BRS3; bombesin receptor subtype-3 K04170 BRS3; bombesin receptor subtype-3
C Bradykinin
D 102102183 BDKRB1; B1 bradykinin receptor K03915 BDKRB1; bradykinin receptor B1
D 102111629 BDKRB2; B2 bradykinin receptor K03916 BDKRB2; bradykinin receptor B2
C Cholecystokinin
D 102110685 CCKAR; cholecystokinin receptor type A K04194 CCKAR; cholecystokinin A receptor
D 102103686 CCKBR; gastrin/cholecystokinin type B receptor K04195 CCKBR; cholecystokinin B receptor
C Endothelin
D 102112626 EDNRA; endothelin-1 receptor K04197 EDNRA; endothelin receptor type A
D 102101313 EDNRB; endothelin B receptor K04198 EDNRB; endothelin receptor type B
D 102107001 endothelin B receptor-like K04198 EDNRB; endothelin receptor type B
C fMet-Leu-Phe
C Follicle stimulating hormone (FSH)
D 102102941 FSHR; follicle-stimulating hormone receptor K04247 FSHR; follicle stimulating hormone receptor
C Galanin
D 102101140 GALR1; galanin receptor type 1 K04230 GALR1; galanin receptor 1
D 102105745 galanin receptor type 1-like K04230 GALR1; galanin receptor 1
D 102105252 GALR2; galanin receptor type 2 K04231 GALR2; galanin receptor 2
D 102109849 GALR3; galanin receptor type 3 K04232 GALR3; galanin receptor 3
C Ghrelin
D 102104523 GHSR; LOW QUALITY PROTEIN: growth hormone secretagogue receptor type 1 K04284 GHSR; growth hormone secretagogue receptor
C Gonadotropin-releasing hormone (GnRH)
D 102105427 gonadotropin-releasing hormone II receptor-like K04280 GNRHR; gonadotropin-releasing hormone receptor
D 102108930 gonadotropin-releasing hormone II receptor-like K04280 GNRHR; gonadotropin-releasing hormone receptor
C Lutropin-choriogonadotropic hormone
D 102103132 LHCGR; lutropin-choriogonadotropic hormone receptor K04248 LHCGR; lutropin-choriogonadotropic hormone receptor
C Melanin-concentrating hormone (MCH)
D 102101722 melanin-concentrating hormone receptor 1-like K04320 MCHR1; melanin-concentrating hormone receptor 1
C Melanocortin
D 106628659 MC1R; melanocyte-stimulating hormone receptor K04199 MC1R; melanocortin 1 receptor
D 102112468 MC2R; adrenocorticotropic hormone receptor K04200 MC2R; melanocortin 2 receptor
D 102107424 MC3R; melanocortin receptor 3 K04201 MC3R; melanocortin 3 receptor
D 102114186 MC4R; melanocortin receptor 4 K04202 MC4R; melanocortin 4 receptor
D 102112158 MC5R; melanocortin receptor 5 K04203 MC5R; melanocortin 5 receptor
C Motilin
D 102099740 MLNR; motilin receptor K05266 MLNR; motilin receptor
C Neuromedin U
D 102101778 NMUR1; neuromedin-U receptor 1 K05052 NMUR1; neuromedin U receptor 1
D 102100300 NMUR2; neuromedin-U receptor 2 K05053 NMUR2; neuromedin U receptor 2
C Neuropeptide FF
D 102099731 NPFFR1; neuropeptide FF receptor 1 K04240 NPFFR1; neuropeptide FF receptor 1
C Neuropeptide S
D 102100468 NPSR1; neuropeptide S receptor K08376 NPSR1; neuropeptide S receptor
C Neuropeptide W / neuropeptide B
D 102106089 NPBWR1; neuropeptides B/W receptor type 1 K05268 NPBWR1; neuropeptides B/W receptor 1
D 102107899 NPBWR2; neuropeptides B/W receptor type 2 K08377 NPBWR2; neuropeptides B/W receptor 2
C Neuropeptide Y
D 102110243 NPY1R; neuropeptide Y receptor type 1 K04204 NPY1R; neuropeptide Y receptor type 1
D 102110970 neuropeptide Y receptor type 2-like K04205 NPY2R; neuropeptide Y receptor type 2
D 102106026 NPY2R; neuropeptide Y receptor type 2 K04205 NPY2R; neuropeptide Y receptor type 2
D 102113552 neuropeptide Y receptor type 4-like K04206 NPY4R; neuropeptide Y receptor type 4
D 102110435 NPY5R; neuropeptide Y receptor type 5 K04207 NPY5R; neuropeptide Y receptor type 5
D 102104826 neuropeptide Y receptor type 6-like K04208 NPY6R; neuropeptide Y receptor type 6
D 102107754 GPR83; probable G-protein coupled receptor 83 K04210 GPR83; G protein-coupled receptor 83
D 102102200 probable G-protein coupled receptor 83 K04210 GPR83; G protein-coupled receptor 83
D 102103556 probable G-protein coupled receptor 83 K04210 GPR83; G protein-coupled receptor 83
C Neurotensin
D 102099336 NTSR1; neurotensin receptor type 1 K04211 NTSR1; neurotensin receptor 1
C Opioid
D 102101358 OPRD1; delta-type opioid receptor isoform X2 K04213 OPRD1; delta-type opioid receptor
D 102106916 OPRK1; kappa-type opioid receptor isoform X1 K04214 OPRK1; kappa-type opioid receptor
D 102110186 OPRM1; mu-type opioid receptor K04215 OPRM1; mu-type opioid receptor
D 102110206 OPRL1; nociceptin receptor K04216 OPRL1; nociceptin receptor
C Orexigenic neuropeptide QRFP
D 102106521 QRFPR; pyroglutamylated RFamide peptide receptor K08378 QRFPR; pyroglutamylated RFamide peptide receptor
C Orexin
D 102105602 HCRTR2; orexin receptor type 2 K04239 HCRTR2; hypocretin (orexin) receptor 2
C Oxytocin
D 102106864 OXTR; oxytocin receptor K04229 OXTR; oxytocin receptor
C Prokineticin
D 102112813 PROKR1; prokineticin receptor 1 K08380 PROKR2; prokineticin receptor 2
C Prolactin-releasing peptide (PrRP)
D 102101764 PRLHR; prolactin-releasing peptide receptor K04314 PRLHR; prolactin releasing hormone receptor
D 102104537 prolactin-releasing peptide receptor-like K04314 PRLHR; prolactin releasing hormone receptor
C Prosaposin
D 102114103 GPR37; prosaposin receptor GPR37 K04243 GPR37; prosaposin receptor
D 102111546 GPR37L1; prosaposin receptor GPR37L1 K04244 GPR37L1; prosaposin receptor
C Relaxin
D 102108491 RXFP1; relaxin receptor 1 K04306 RXFP1; relaxin family peptide receptor 1
D 102100683 RXFP3; relaxin-3 receptor 1 K08397 RXFP3; relaxin family peptide receptor 3
C Somatostatin
D 102108317 SSTR1; somatostatin receptor type 1 K04217 SSTR1; somatostatin receptor 1
D 102113642 SSTR2; somatostatin receptor type 2 K04218 SSTR2; somatostatin receptor 2
D 102106756 SSTR3; somatostatin receptor type 3 K04219 SSTR3; somatostatin receptor 3
D 102101534 SSTR4; somatostatin receptor type 4 K04220 SSTR4; somatostatin receptor 4
D 102100002 SSTR5; somatostatin receptor type 5 K04221 SSTR5; somatostatin receptor 5
C Tachykinin
D 102104311 TACR1; substance-P receptor K04222 TACR1; tachykinin receptor 1
D 102102338 TACR2; substance-K receptor K04223 TACR2; tachykinin receptor 2
D 102111130 TACR3; neuromedin-K receptor K04224 TACR3; tachykinin receptor 3
C Thrombin
D 102108910 F2R; proteinase-activated receptor 1 isoform X1 K03914 F2R; coagulation factor II (thrombin) receptor
D 102110361 F2RL1; proteinase-activated receptor 2 K04234 F2RL1; coagulation factor II (thrombin) receptor-like 1
D 106628685 F2RL2; proteinase-activated receptor 3 K04235 F2RL2; coagulation factor II (thrombin) receptor-like 2
D 102105271 F2RL3; LOW QUALITY PROTEIN: proteinase-activated receptor 4 K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
C Thyrotropin
D 102111924 TSHR; thyrotropin receptor isoform X1 K04249 TSHR; thyrotropin receptor
C Thyrotropin-releasing hormone (TRH)
D 102114270 TRHR; thyrotropin-releasing hormone receptor K04282 TRHR; thyrotropin-releasing hormone receptor
D 102100543 thyrotropin-releasing hormone receptor-like K04282 TRHR; thyrotropin-releasing hormone receptor
C Urotensin II
D 102110153 urotensin-2 receptor-like isoform X1 K04241 UTS2R; urotensin 2 receptor
D 102110341 urotensin-2 receptor-like K04241 UTS2R; urotensin 2 receptor
D 102101973 LOW QUALITY PROTEIN: urotensin-2 receptor-like K04241 UTS2R; urotensin 2 receptor
C Vasopressin
D 102110756 AVPR1A; vasopressin V1a receptor K04226 AVPR1A; arginine vasopressin receptor 1A
D 102105205 AVPR1B; vasopressin V1b receptor K04227 AVPR1B; arginine vasopressin receptor 1B
D 102104327 arg8-vasotocin receptor-like K04228 AVPR2; arginine vasopressin receptor 2
D 102111850 AVPR2; vasopressin V2 receptor K04228 AVPR2; arginine vasopressin receptor 2
C Neuropeptide receptors
B Chemokine
C CC Chemokine
D 102105048 CCR4; C-C chemokine receptor type 4 K04179 CCR4; C-C chemokine receptor type 4
D 102103905 C-C chemokine receptor type 5-like K04180 CCR5; C-C chemokine receptor type 5
D 102103721 C-C chemokine receptor type 5-like K04180 CCR5; C-C chemokine receptor type 5
D 102105566 CCR6; C-C chemokine receptor type 6 K04181 CCR6; C-C chemokine receptor type 6
D 102111785 CCR7; C-C chemokine receptor type 7 K04182 CCR7; C-C chemokine receptor type 7
D 102114533 C-C chemokine receptor type 8-like K04183 CCR8; C-C chemokine receptor type 8
D 102114717 CCR9; C-C chemokine receptor type 9 K04184 CCR9; C-C chemokine receptor type 9
D 102101193 CCR10; C-C chemokine receptor type 10 K04185 CCR10; C-C chemokine receptor type 10
D 102109743 ACKR1; atypical chemokine receptor 1 K06574 ACKR1; atypical chemokine receptor 1
D 102112308 ACKR2; atypical chemokine receptor 2 K04187 ACKR2; atypical chemokine receptor 2
D 102102063 ACKR4; LOW QUALITY PROTEIN: atypical chemokine receptor 4 K04186 ACKR4; atypical chemokine receptor 4
D 102099158 GPR75; probable G-protein coupled receptor 75 K08417 GPR75; G protein-coupled receptor 75
C CXC Chemokine
D 102101581 C-X-C chemokine receptor type 2-like K05050 CXCR2; C-X-C chemokine receptor type 2
D 102099500 CXCR4; C-X-C chemokine receptor type 4 K04189 CXCR4; C-X-C chemokine receptor type 4
D 102112086 CXCR5; C-X-C chemokine receptor type 5 K04190 CXCR5; C-X-C chemokine receptor type 5
D 102108965 ACKR3; atypical chemokine receptor 3 K04304 CXCR7; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
D 102114312 G-protein coupled receptor 35-like isoform X1 K04276 CXCR8; C-X-C chemokine receptor type 8
D 102114507 G-protein coupled receptor 35-like K04276 CXCR8; C-X-C chemokine receptor type 8
D 106628514 G-protein coupled receptor 35-like K04276 CXCR8; C-X-C chemokine receptor type 8
C CX3C Chemokine
D 102105231 CX3C chemokine receptor 1 K04192 CX3CR1; CX3C chemokine receptor 1
C C Chemokine
D 102104082 XCR1; chemokine XC receptor 1 K04193 XCR1; XC chemokine receptor 1
C Chemokine like
D 102114484 chemokine-like receptor 1 K04245 CMKLR1; chemokine-like receptor 1
D 102103551 CMKLR1; chemokine-like receptor 1 K04245 CMKLR1; chemokine-like receptor 1
D 102100658 GPR1; G-protein coupled receptor 1 K04310 GPR1; G protein-coupled receptor 1
D 102111883 GPR15; G-protein coupled receptor 15 K08403 GPR15; G protein-coupled receptor 15
B Base and nucleoside
C Purine / pyrimidine
D 106628032 P2Y purinoceptor 1-like K04270 P2RY1; P2Y purinoceptor 1
D 102110902 P2RY1; P2Y purinoceptor 1 K04270 P2RY1; P2Y purinoceptor 1
D 102100005 P2Y purinoceptor 1-like K04270 P2RY1; P2Y purinoceptor 1
D 102112618 P2RY2; P2Y purinoceptor 2 K04269 P2RY2; P2Y purinoceptor 2
D 102101720 P2RY4; P2Y purinoceptor 4 K04271 P2RY4; P2Y purinoceptor 4
D 102112428 P2RY6; P2Y purinoceptor 6 K04272 P2RY6; P2Y purinoceptor 6
D 102112333 P2RY8; P2Y purinoceptor 8 K08386 P2RY8; P2Y purinoceptor 8
D 102111713 P2Y purinoceptor 12 K04298 P2RY12; P2Y purinoceptor 12
D 102108580 P2Y purinoceptor 13 K08388 P2RY13; P2Y purinoceptor 13
D 102108755 P2RY14; P2Y purinoceptor 14 K04299 P2RY14; P2Y purinoceptor 14
D 102108219 SUCNR1; succinate receptor 1 K10042 SUCNR1; succinate receptor 1
C Adenosine
D 102104539 adenosine receptor A1 K04265 ADORA1; adenosine receptor A1
D 102111270 ADORA2A; adenosine receptor A2a K04266 ADORA2A; adenosine receptor A2a
D 102107785 ADORA2B; adenosine receptor A2b K04267 ADORA2B; adenosine receptor A2b
D 102100812 ADORA3; adenosine receptor A3 K04268 ADORA3; adenosine receptor A3
B Lipid
C Arachidonylglycine
D 102106538 GPR18; N-arachidonyl glycine receptor K08410 GPR18; N-arachidonyl glycine receptor
C Bile acid
C Cysteinyl leukotriene
D 102101344 CYSLTR1; cysteinyl leukotriene receptor 1 K04322 CYSLTR1; cysteinyl leukotriene receptor 1
D 102099926 CYSLTR2; cysteinyl leukotriene receptor 2 K04323 CYSLTR2; cysteinyl leukotriene receptor 2
C Free fatty acid
D 102106038 FFAR4; free fatty acid receptor 4 isoform X1 K08425 FFAR4; free fatty acid receptor 4
C HETE and oxoETE
C Leukotriene
D 102105374 leukotriene B4 receptor 1-like K04296 LTB4R1; leukotriene B4 receptor 1
C Lysophosphatidic acid
D 102105561 lysophosphatidic acid receptor 1-like K04289 LPAR1; lysophosphatidic acid receptor 1
D 102111782 LPAR1; lysophosphatidic acid receptor 1 K04289 LPAR1; lysophosphatidic acid receptor 1
D 102112903 LPAR2; lysophosphatidic acid receptor 2 K04291 LPAR2; lysophosphatidic acid receptor 2
D 102111144 LPAR3; lysophosphatidic acid receptor 3 K04294 LPAR3; lysophosphatidic acid receptor 3
D 102099403 LPAR4; lysophosphatidic acid receptor 4 K04275 LPAR4; lysophosphatidic acid receptor 4
D 102113993 LPAR5; lysophosphatidic acid receptor 5 K08390 LPAR5; lysophosphatidic acid receptor 5
D 102104985 LPAR6; lysophosphatidic acid receptor 6 K04273 LPAR6; lysophosphatidic acid receptor 6
D 102111887 GPR87; G-protein coupled receptor 87 isoform X2 K08389 GPR87; G protein-coupled receptor 87
C Lysophosphatidylinositol
D 102114135 G-protein coupled receptor 55-like K08413 GPR55; G protein-coupled receptor 55
C Lysophosphatidylserine
D 102103320 probable G-protein coupled receptor 34 K08383 GPR34; G protein-coupled receptor 34
D 102100977 putative P2Y purinoceptor 10 K04274 P2RY10; P2Y purinoceptor 10
D 102101170 putative P2Y purinoceptor 10 K04274 P2RY10; P2Y purinoceptor 10
D 102100798 GPR174; probable G-protein coupled receptor 174 K08391 GPR174; G protein-coupled receptor 174
C Oleoylethanolamide
D 102106636 GPR119; glucose-dependent insulinotropic receptor K08424 GPR119; glucose-dependent insulinotropic receptor
C Prostaglandin
D 102103446 PTGDR; prostaglandin D2 receptor K04332 PTGDR; prostaglandin D2 receptor
D 102103262 PTGER2; prostaglandin E2 receptor EP2 subtype K04259 PTGER2; prostaglandin E receptor 2
D 102111740 PTGER3; prostaglandin E2 receptor EP3 subtype K04260 PTGER3; prostaglandin E receptor 3
D 102112129 PTGER4; prostaglandin E2 receptor EP4 subtype K04261 PTGER4; prostaglandin E receptor 4
D 102113860 PTGFR; prostaglandin F2-alpha receptor isoform X1 K04262 PTGFR; prostaglandin F receptor
C Prostacyclin
C Sphingolipid
D 102113554 S1PR1; sphingosine 1-phosphate receptor 1 K04288 S1PR1; sphingosine 1-phosphate receptor 1
D 102114759 S1PR2; sphingosine 1-phosphate receptor 2 K04292 S1PR2; sphingosine 1-phosphate receptor 2
D 102110353 S1PR3; sphingosine 1-phosphate receptor 3 K04290 S1PR3; sphingosine 1-phosphate receptor 3
D 102102587 S1PR4; sphingosine 1-phosphate receptor 4 K04293 S1PR4; sphingosine 1-phosphate receptor 4
C Thromboxane
D 102103217 TBXA2R; thromboxane A2 receptor K04264 TBXA2R; thromboxane A2 receptor
B Vision
C Opsin
D 102104938 RHO; rhodopsin K04250 RHO; rhodopsin
D 102110095 green-sensitive opsin K04250 RHO; rhodopsin
D 102108119 blue-sensitive opsin K04252 OPN1SW; short wavelength-sensitive opsin
D 102108366 OPN1SW; short-wave-sensitive opsin 1 K04252 OPN1SW; short wavelength-sensitive opsin
D 102107428 pinopsin K04251 OPN1LW; long/medium wavelength-sensitive opsin
D 102106721 red-sensitive opsin K04251 OPN1LW; long/medium wavelength-sensitive opsin
D 102110002 opsin-3-like K04256 OPN3; c-opsin
D 102109878 OPN3; opsin-3 K04256 OPN3; c-opsin
D 102103328 vertebrate ancient opsin-like K04256 OPN3; c-opsin
D 102114685 LOW QUALITY PROTEIN: pinopsin-like K04256 OPN3; c-opsin
D 102102920 melanopsin-like K04255 OPN4; r-opsin
D 102107412 OPN4; melanopsin K04255 OPN4; r-opsin
D 102112990 OPN5; opsin-5 K08385 OPN5; G0-opsin
D 102111765 opsin-5-like K08385 OPN5; G0-opsin
D 102112602 RRH; visual pigment-like receptor peropsin K04253 RRH; visual pigment-like receptor peropsin
D 102111141 RGR; RPE-retinal G protein-coupled receptor K04254 RGR; retinal G protein coupled receptor
B Others
C Alpha-ketoglutarate
D 102104500 OXGR1; 2-oxoglutarate receptor 1 K08419 OXGR1; oxoglutarate (alpha-ketoglutarate) receptor 1
C Cannabinoid
D 102104259 CNR1; cannabinoid receptor 1 K04277 CNR1; cannabinoid receptor 1
D 102112261 CNR2; cannabinoid receptor 2 K04278 CNR2; cannabinoid receptor 2
C Estrogen
D 102101274 GPER1; G-protein coupled estrogen receptor 1 K04246 GPER1; G-protein coupled estrogen receptor 1
C Hydroxy-carboxylic acid
C L-Tryptophan and L-Phenylalanine
D 102106369 GPR139; probable G-protein coupled receptor 139 K08428 GPR139; G protein-coupled receptor 139
D 106628578 GPR142; probable G-protein coupled receptor 142 K08430 GPR142; G protein-coupled receptor 142
C Mas proto-oncogene and Mas-related (MRGs)
D 102104687 MAS1; proto-oncogene Mas K04303 MAS1; proto-oncogene Mas
C Melatonin
D 102108252 MTNR1A; melatonin receptor type 1A K04285 MTNR1A; melatonin receptor type 1A
D 102103764 GPR50; melatonin-related receptor K04285 MTNR1A; melatonin receptor type 1A
D 102105967 MTNR1B; melatonin receptor type 1B K04286 MTNR1B; melatonin receptor type 1B
C Oxysterol
D 102104857 G-protein coupled receptor 183-like K04305 EBI2; Epstein-Barr virus induced gene 2
D 102106348 GPR183; LOW QUALITY PROTEIN: G-protein coupled receptor 183 K04305 EBI2; Epstein-Barr virus induced gene 2
C Platelet activating factor
D 102108046 PTAFR; platelet-activating factor receptor K04279 PTAFR; platelet-activating factor receptor
C Proton-sensing GPCRs
D 102113670 GPR65; psychosine receptor K08416 GPR65; psychosine receptor
D 102113107 GPR68; ovarian cancer G-protein coupled receptor 1 K08408 GPR68; ovarian cancer G-protein coupled receptor 1
D 102108864 GPR132; probable G-protein coupled receptor 132 K08426 GPR132; G protein-coupled receptor 132
C R-spondin
D 102106325 LGR4; leucine-rich repeat-containing G-protein coupled receptor 4 isoform X1 K04309 LGR4; leucine-rich repeat-containing G protein-coupled receptor 4
D 102102928 LGR5; leucine-rich repeat-containing G-protein coupled receptor 5 K04308 LGR5; leucine-rich repeat-containing G protein-coupled receptor 5
D 102111903 LGR6; leucine-rich repeat-containing G-protein coupled receptor 6 K08399 LGR6; leucine-rich repeat-containing G protein-coupled receptor 6
C Super conserved receptor expressed in brain (SREB)
D 102110504 GPR27; probable G-protein coupled receptor 27 K04301 SREB1; super conserved receptor expressed in brain 1
D 102102244 GPR85; probable G-protein coupled receptor 85 K04302 SREB2; super conserved receptor expressed in brain 2
C Trissin
C Orphan GPCRs / unclassified GPCRs
D 102103028 GPR3; G-protein coupled receptor 3 K04311 GPR3; G protein-coupled receptor 3
D 102101321 GPR6; G-protein coupled receptor 6 K04313 GPR6; G protein-coupled receptor 6
D 102106086 GPR12; G-protein coupled receptor 12 K04315 GPR12; G protein-coupled receptor 12
D 102108821 LOW QUALITY PROTEIN: G-protein coupled receptor 12-like K04315 GPR12; G protein-coupled receptor 12
D 102101918 GPR17; uracil nucleotide/cysteinyl leukotriene receptor K08404 GPR17; G protein-coupled receptor 17
D 102103953 GPR20; G-protein coupled receptor 20 K04317 GPR20; G protein-coupled receptor 20
D 102108771 GPR21; probable G-protein coupled receptor 21 K04318 GPR21; G protein-coupled receptor 21
D 102102989 GPR22; probable G-protein coupled receptor 22 K04319 GPR22; G protein-coupled receptor 22
D 102108253 GPR78; G-protein coupled receptor 78 K08411 GPR26; G protein-coupled receptor 26
D 102110413 GPR26; G-protein coupled receptor 26 K08411 GPR26; G protein-coupled receptor 26
D 102102423 GPR39; G-protein coupled receptor 39 K08412 GPR39; G protein-coupled receptor 39
D 102105024 GPR52; probable G-protein coupled receptor 52 K08407 GPR52; G protein-coupled receptor 52
D 102099622 GPR62; LOW QUALITY PROTEIN: probable G-protein coupled receptor 62 K08414 GPR61; G protein-coupled receptor 61
D 102110605 GPR61; probable G-protein coupled receptor 61 K08414 GPR61; G protein-coupled receptor 61
D 102108858 GPR63; probable G-protein coupled receptor 63 K04321 GPR63; G protein-coupled receptor 63
D 102105178 GPR88; probable G-protein coupled receptor 88 K08422 GPR88; G protein-coupled receptor 88
D 102107767 GPR135; probable G-protein coupled receptor 135 K08427 GPR135; G protein-coupled receptor 135
D 102112229 GPR141; probable G-protein coupled receptor 141 isoform X1 K08429 GPR141; G protein-coupled receptor 141
D 102101016 probable G-protein coupled receptor 141 K08429 GPR141; G protein-coupled receptor 141
D 102101094 GPR146; probable G-protein coupled receptor 146 K08431 GPR146; G protein-coupled receptor 146
D 102099903 GPR148; probable G-protein coupled receptor 148 K08432 GPR148; G protein-coupled receptor 148
D 102107671 GPR149; probable G-protein coupled receptor 149 K08433 GPR149; G protein-coupled receptor 149
D 102104708 GPR160; probable G-protein coupled receptor 160 K08438 GPR160; G protein-coupled receptor 160
D 102099451 GPR161; G-protein coupled receptor 161 K08439 GPR161; G protein-coupled receptor 161
D 102112294 GPR162; probable G-protein coupled receptor 162 K08440 GPR162; G protein-coupled receptor 162
D 102103851 GPR176; probable G-protein coupled receptor 176 K08442 GPR176; G protein-coupled receptor 176
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ASecretin receptor family
B Calcium-regulating peptide
C Calcitonin
D 102099496 CALCR; calcitonin receptor K04576 CALCR; calcitonin receptor
D 102112579 CALCRL; calcitonin gene-related peptide type 1 receptor K04577 CALCRL; calcitonin receptor-like
C Parathyroid hormone
D 102113833 PTH1R; parathyroid hormone/parathyroid hormone-related peptide receptor K04585 PTH1R; parathyroid hormone receptor 1
D 102102716 parathyroid hormone/parathyroid hormone-related peptide receptor-like K04585 PTH1R; parathyroid hormone receptor 1
B Hypothalamic hormone
C Corticotropin-releasing hormone (CRH)
D 102099242 CRHR1; corticotropin-releasing factor receptor 1 isoform X1 K04578 CRHR1; corticotropin releasing hormone receptor 1
D 102110154 CRHR2; corticotropin-releasing factor receptor 2 isoform X1 K04579 CRHR2; corticotropin releasing hormone receptor 2
C Growth hormone-releasing hormone (GHRH)
D 102101286 GHRHR; growth hormone-releasing hormone receptor K04584 GHRHR; growth hormone releasing hormone receptor
B Pancreatic peptide
C Glucagon
D 102106718 GLP1R; glucagon-like peptide 1 receptor K04581 GLP1R; glucagon-like peptide 1 receptor
D 102113072 GLP2R; glucagon-like peptide 2 receptor K04582 GLP2R; glucagon-like peptide 2 receptor
D 102113562 glucagon receptor-like K04583 GCGR; glucagon receptor
D 102106460 GCGR; glucagon receptor K04583 GCGR; glucagon receptor
B Gut peptide
C Gastric inhibitory peptide (GIP)
D 102105158 GIPR; gastric inhibitory polypeptide receptor K04580 GIPR; gastric inhibitory polypeptide receptor
C Vasoactive intestinal polypeptide (VIP) and pituitary adenyl cyclase-activating peptide (PACAP)
D 102110911 vasoactive intestinal polypeptide receptor K04589 VIPR1; vasoactive intestinal peptide receptor 1
D 102101369 vasoactive intestinal polypeptide receptor 1-like K04589 VIPR1; vasoactive intestinal peptide receptor 1
D 102101469 vasoactive intestinal polypeptide receptor 1-like K04589 VIPR1; vasoactive intestinal peptide receptor 1
D 102102332 VIPR2; vasoactive intestinal polypeptide receptor 2 K04590 VIPR2; vasoactive intestinal peptide receptor 2
D 102110717 ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor K04587 ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor
C Secretin
D 102104868 SCTR; secretin receptor isoform X1 K04588 SCTR; secretin receptor
B Others
C Receptor activity modifying protein
D 102103761 RAMP2; receptor activity-modifying protein 2 K08448 RAMP2; receptor activity modifying protein 2
D 102110459 RAMP3; receptor activity-modifying protein 3 K08449 RAMP3; receptor activity modifying protein 3
C Methuselah-like proteins (MTH)
C Pigment dispersing factor (PDF)
#
AAdhesion receptor family
B Cadherin EGF LAG (CELSR)
C 102106666 CELSR1; cadherin EGF LAG seven-pass G-type receptor 1 K04600 CELSR1; cadherin EGF LAG seven-pass G-type receptor 1
C 102099535 CELSR2; cadherin EGF LAG seven-pass G-type receptor 2 K04601 CELSR2; cadherin EGF LAG seven-pass G-type receptor 2
C 102112803 CELSR3; cadherin EGF LAG seven-pass G-type receptor 3 isoform X1 K04602 CELSR3; cadherin EGF LAG seven-pass G-type receptor 3
B EGF-like module-containing mucin-like hormone receptor-like (EMR)
B Latrophilin
C 102101062 ADGRL1; latrophilin-1 K04592 ADGRL1; adhesion G protein-coupled receptor L1
C 102113303 ADGRL2; adhesion G protein-coupled receptor L2 isoform X1 K04593 ADGRL2; adhesion G protein-coupled receptor L2
C 102111475 ADGRL3; latrophilin-3 isoform X1 K04594 ADGRL3; adhesion G protein-coupled receptor L3
C 102113488 ADGRL4; adhesion G protein-coupled receptor L4 K04595 ADGRL4; adhesion G protein-coupled receptor L4
B Brain-specific angiogenesis inhibitor (BAI)
C 102111128 ADGRB1; brain-specific angiogenesis inhibitor 1 K04596 ADGRB1; adhesion G protein-coupled receptor B1
C 102103753 ADGRB2; adhesion G protein-coupled receptor B2 K04597 ADGRB2; adhesion G protein-coupled receptor B2
C 102108618 ADGRB3; adhesion G protein-coupled receptor B3 K04598 ADGRB3; adhesion G protein-coupled receptor B3
B Others
C 102109717 ADGRA1; adhesion G protein-coupled receptor A1 K08460 ADGRA1; adhesion G protein-coupled receptor A1
C 102111843 ADGRA2; G-protein coupled receptor 124 K08461 ADGRA2; adhesion G protein-coupled receptor A2
C 102112909 ADGRA3; adhesion G protein-coupled receptor A3 isoform X1 K08462 ADGRA3; adhesion G protein-coupled receptor A3
C 102104282 ADGRD1; adhesion G-protein coupled receptor D1 isoform X1 K08465 ADGRD1; adhesion G-protein coupled receptor D1
C 102105879 ADGRD2; adhesion G-protein coupled receptor D2 K08466 ADGRD2; adhesion G-protein coupled receptor D2
C 102113989 adhesion G protein-coupled receptor F4 K08457 ADGRF4; adhesion G-protein coupled receptor F4
C 102112484 ADGRF5; adhesion G protein-coupled receptor F5 K08458 ADGRF5; adhesion G-protein coupled receptor F5
C 102108164 G-protein coupled receptor 56 isoform X1 K08450 ADGRG1; adhesion G-protein coupled receptor G1
C 102111497 ADGRG2; adhesion G-protein coupled receptor G2 isoform X1 K08451 ADGRG2; adhesion G-protein coupled receptor G2
C 102112949 ADGRG3; adhesion G protein-coupled receptor G3 K08452 ADGRG3; adhesion G-protein coupled receptor G3
C 102099929 ADGRG6; G-protein coupled receptor 126 isoform X1 K08463 ADGRG6; adhesion G-protein coupled receptor G6
C 102102687 ADGRG7; LOW QUALITY PROTEIN: adhesion G-protein coupled receptor G7 K08464 ADGRG7; adhesion G-protein coupled receptor G7
C 102110544 ADGRV1; G-protein coupled receptor 98 K18263 ADGRV1; adhesion G-protein coupled receptor V1
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AMetabotropic glutamate receptor family
B Glutamate (metabotropic)
C 102107527 GRM1; metabotropic glutamate receptor 1 isoform X1 K04603 GRM1; metabotropic glutamate receptor 1
C 102105121 GRM2; metabotropic glutamate receptor 2 K04605 GRM2; metabotropic glutamate receptor 2
C 102113129 GRM3; metabotropic glutamate receptor 3 isoform X1 K04606 GRM3; metabotropic glutamate receptor 3
C 102110281 GRM4; metabotropic glutamate receptor 4 K04607 GRM4; metabotropic glutamate receptor 4
C 102104616 GRM5; metabotropic glutamate receptor 5 K04604 GRM5; metabotropic glutamate receptor 5
C 102107228 GRM7; metabotropic glutamate receptor 7 K04609 GRM7; metabotropic glutamate receptor 7
C 102110564 GRM8; metabotropic glutamate receptor 8 K04610 GRM8; metabotropic glutamate receptor 8
B GABA
C 102099306 GABBR1; gamma-aminobutyric acid type B receptor subunit 1 K04615 GABBR; gamma-aminobutyric acid type B receptor
C 102106353 GABBR2; gamma-aminobutyric acid type B receptor subunit 2 K04615 GABBR; gamma-aminobutyric acid type B receptor
C 102099763 GPR156; LOW QUALITY PROTEIN: probable G-protein coupled receptor 156 K04617 GPR156; gamma-aminobutyric acid type B receptor-like
B Calcium-sensing
C 102101160 CASR; extracellular calcium-sensing receptor K04612 CASR; calcium-sensing receptor
C 102107032 GPRC6A; G-protein coupled receptor family C group 6 member A K04622 GPRC6A; G protein-coupled receptor family C group 6 member A
B Orphan GPRC5
C 102113135 retinoic acid-induced protein 3 K08468 GPRC5A; G protein-coupled receptor family C group 5 member A
C 102106046 GPRC5B; G-protein coupled receptor family C group 5 member B K04619 GPRC5B; G protein-coupled receptor family C group 5 member B
C 102112264 GPRC5C; G-protein coupled receptor family C group 5 member C isoform X1 K04620 GPRC5C; G protein-coupled receptor family C group 5 member C
B Unclassified GPCRs
C 102102926 GPR158; probable G-protein coupled receptor 158 K08469 GPR158; G protein-coupled receptor 158
C 102106534 GPR179; LOW QUALITY PROTEIN: probable G-protein coupled receptor 179 K22961 GPR179; G protein-coupled receptor 179
#
AFrizzled / Smoothened family
B 102102804 FZD7; frizzled-7 K02432 FZD1_7; frizzled 1/7
B 102113044 FZD1; frizzled-1 K02432 FZD1_7; frizzled 1/7
B 102114200 FZD2; frizzled-2 K02235 FZD2; frizzled 2
B 102105570 FZD3; frizzled-3 K02329 FZD3; frizzled 3
B 102103650 FZD4; frizzled-4 K02354 FZD4; frizzled 4
B 102101759 FZD5; frizzled-5 K02375 FZD5_8; frizzled 5/8
B 102102740 FZD8; LOW QUALITY PROTEIN: frizzled-8 K02375 FZD5_8; frizzled 5/8
B 102099310 FZD6; frizzled-6 K02376 FZD6; frizzled 6
B 102102880 FZD9; frizzled-9 K02842 FZD9_10; frizzled 9/10
B 102105130 FZD10; frizzled-10 K02842 FZD9_10; frizzled 9/10
B 102107642 SMO; smoothened homolog K06226 SMO; smoothened
#
AOthers
B Chemoreception
C Olfactory
D 102111390 olfactory receptor 10AC1 K04257 OLFR; olfactory receptor
D 102112461 olfactory receptor 49-like K04257 OLFR; olfactory receptor
D 102112840 olfactory receptor 10A5-like K04257 OLFR; olfactory receptor
D 102113225 olfactory receptor 12-like K04257 OLFR; olfactory receptor
D 102113410 olfactory receptor 6Y1-like K04257 OLFR; olfactory receptor
D 102113602 olfactory receptor 6B1-like K04257 OLFR; olfactory receptor
D 102113969 olfactory receptor 10C1-like K04257 OLFR; olfactory receptor
D 102112189 olfactory receptor 51G2-like K04257 OLFR; olfactory receptor
D 102112369 olfactory receptor 51E2-like K04257 OLFR; olfactory receptor
D 102112941 olfactory receptor 52B2-like K04257 OLFR; olfactory receptor
D 102101995 olfactory receptor 14I1-like K04257 OLFR; olfactory receptor
D 102102171 olfactory receptor 14J1-like K04257 OLFR; olfactory receptor
D 102101122 olfactory receptor 4D5-like K04257 OLFR; olfactory receptor
D 102101300 olfactory receptor 1019-like K04257 OLFR; olfactory receptor
D 102111102 olfactory receptor 8U9-like K04257 OLFR; olfactory receptor
D 102104354 olfactory receptor 1019-like K04257 OLFR; olfactory receptor
D 102112331 olfactory receptor 6F1-like K04257 OLFR; olfactory receptor
D 102111186 olfactory receptor 14J1-like K04257 OLFR; olfactory receptor
D 102113094 olfactory receptor 14A16-like K04257 OLFR; olfactory receptor
D 102112012 LOW QUALITY PROTEIN: olfactory receptor 52K2-like K04257 OLFR; olfactory receptor
D 106628353 olfactory receptor 52I1-like K04257 OLFR; olfactory receptor
D 102100937 LOW QUALITY PROTEIN: olfactory receptor 4S2-like K04257 OLFR; olfactory receptor
D 102110919 LOW QUALITY PROTEIN: olfactory receptor 1052-like K04257 OLFR; olfactory receptor
D 102110937 LOW QUALITY PROTEIN: olfactory receptor 14J1-like K04257 OLFR; olfactory receptor
D 106628776 olfactory receptor 5V1-like K04257 OLFR; olfactory receptor
D 102113031 LOW QUALITY PROTEIN: olfactory receptor 4D2-like K04257 OLFR; olfactory receptor
C Taste
D 102107259 taste receptor type 1 member 3 K04626 TAS1R3; taste receptor type 1 member 3
D 102110644 taste receptor type 2 member 40-like K08474 TAS2R; taste receptor type 2
D 102110835 taste receptor type 2 member 40-like K08474 TAS2R; taste receptor type 2
D 102105285 taste receptor type 2 member 8-like K08474 TAS2R; taste receptor type 2
D 102106130 taste receptor type 2 member 9-like K08474 TAS2R; taste receptor type 2
D 102112634 taste receptor type 2 member 7-like K08474 TAS2R; taste receptor type 2
C Vomeronasal pheromone
C Insect odorant and taste
C Nematode chemoreception
C Fungal mating pheromone
B Others
C Ocular albinism proteins
D 102102175 GPR143; G-protein coupled receptor 143 K08470 OA1; ocular albinism type 1 protein
C Neuronostatin
D 102113942 GPR107; protein GPR107 isoform X1 K22985 GPR107; G protein-coupled receptor 107
C Plant Mlo receptors
C cAMP signaling
C Bacterial rhodopsin
C Orphan GPCRs
D 102111442 TPRA1; transmembrane protein adipocyte-associated 1 K22988 TPRA1; transmembrane protein adipocyte-associated 1
D 102103081 GPR137C; integral membrane protein GPR137C K22989 GPR137; integral membrane protein GPR137
D 102112412 GPR137B; integral membrane protein GPR137B isoform X1 K22989 GPR137; integral membrane protein GPR137
D 102102899 GPR157; probable G-protein coupled receptor 157 isoform X2 K08467 GPR157; G protein-coupled receptor 157
!
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 8, 2022
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Classification taken and modified from GPCRDB