+E Ubiquitin system KO
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Ubiquitin System - Plasmodium knowlesi
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C PKNH_1311900 polyubiquitin, putative K08770 UBC; ubiquitin C
C PKNH_1105400 ubiquitin/ribosomal fusion protein uba52-like protein K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C PKNH_1355500 ribosomal protein S27a, putative K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C PKNH_1413600 ubiquitin-like protein K12158 NEDD8; ubiquitin-like protein Nedd8
C PKNH_0401700 40S ribosomal protein S30, putative K02983 RP-S30e; small subunit ribosomal protein S30e
C PKNH_0604100 autophagy-related protein 8, putative K08341 GABARAP; GABA(A) receptor-associated protein
C PKNH_0936300 ubiquitin-related modifier 1, putative K12161 URM1; ubiquitin related modifier 1
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C PKNH_1445200 ubiquitin-activating enzyme E1, putative K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C PKNH_0942400 SUMO-activating enzyme subunit 1, putative K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C PKNH_1456700 SUMO-activating enzyme subunit 2, putative K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C PKNH_0503400 NEDD8-activating enzyme E1 catalytic subunit, putative K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C PKNH_1105900 ubiquitin-activating enzyme, putative K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C PKNH_1428000 ubiquitin-conjugating enzyme E2, putative K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C PKNH_0821900 ubiquitin-conjugating enzyme E2, putative K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
C PKNH_1303600 ubiquitin-conjugating enzyme E2, putative K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C PKNH_0719000 ubiquitin-conjugating enzyme E2, putative K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C PKNH_0619100 ubiquitin-conjugating enzyme E2, putative K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C PKNH_1115200 ubiquitin-conjugating enzyme E2, putative K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C PKNH_1005600 ubiquitin-conjugating enzyme E2 N, putative K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C PKNH_1345400 ubiquitin-conjugating enzyme E2, putative K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C PKNH_1144000 ubiquitin-conjugating enzyme E2 PEX4, putative K10689 PEX4; peroxin-4 [EC:2.3.2.23]
B UBL-conjugating enzymes
C PKNH_0713100 SUMO-conjugating enzyme UBC9, putative K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C PKNH_1465000 NEDD8-conjugating enzyme UBC12, putative K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C PKNH_0703400 autophagy-related protein 3, putative K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C PKNH_0911900 RAP protein, putative K12165 UFC1; ufm1-conjugating enzyme 1
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AUbiquitin ligases (E3)
B HECT type E3
C HECT type E3 associated proteins
B U-box type E3
C PKNH_0106200 E3 ubiquitin-protein ligase, putative K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C PKNH_0729200 peptidyl-prolyl cis-trans isomerase, putative K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C PKNH_0834100 uncharacterized protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
B Single Ring-finger type E3
C BRE1 proteins
D PKNH_1147300 trophozoite exported protein 1, putative K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
C SINA (Seven in absentia) proteins
C Ligand of Numb proteins
C March proteins
C MDM2/MDM4 proteins
C NFX1 proteins
C Pellino proteins
C Peripheral membrane proteins
C RBR proteins
C TRAF proteins
C TRIM/RBCC proteins
C UBR box proteins
C ATL proteins
C Other single Ring-finger type E3
D PKNH_1455000 uncharacterized protein K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D PKNH_0411400 RING zinc finger protein, putative K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D PKNH_0816700 U4/U6.U5 tri-snRNP-associated protein 1, putative K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D PKNH_1335500 ERAD-associated E3 ubiquitin-protein ligase HRD1, putative K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D PKNH_0830300 E3 ubiquitin-protein ligase, putative K23788 TUL1; transmembrane E3 ubiquitin-protein ligase [EC:2.3.2.27]
B Atypical E3
C PKNH_1102900 conserved Plasmodium protein, unknown function K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
B UBL E3 ligases
C PKNH_0822400 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E PKNH_0822400 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E PKNH_1429700 cullin-1, putative K03347 CUL1; cullin 1
D Adaptor protein
E PKNH_1104200 suppressor of kinetochore protein 1, putative K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
C Cul2 complex
D Ring finger protein
E PKNH_0822400 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adoptor protein
D Target recognizing subunit
C Cul3 complex
D Ring finger protein
E PKNH_0822400 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adoptor and target recognizing subunit (BTB)
E PKNH_1221600 kelch domain-containing protein, putative K23330 LZTR1; leucine-zipper-like transcriptional regulator 1
C Cul4 complex
D Ring finger protein
E PKNH_0822400 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adoptor protein
D Target recognizing subunit (DCAF)
E PKNH_0307200 protein SOF1, putative K11806 DCAF13; DDB1- and CUL4-associated factor 13
E PKNH_0618300 WD repeat-containing protein 70, putative K24752 WDR70; WD repeat-containing protein 70
C Cul5 complex
D Ring finger protein
D Cullin
D Adoptor protein
D Target recognizing subunit
C Cul7 complex
D Ring finger protein
E PKNH_0822400 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E PKNH_1104200 suppressor of kinetochore protein 1, putative K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E PKNH_0822400 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E PKNH_0822400 E3 ubiquitin-protein ligase RBX1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
E PKNH_1125700 anaphase-promoting complex subunit 11, putative K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
D Target recognizing subunit
E PKNH_0610900 uncharacterized protein K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E PKNH_1437200 anaphase-promoting complex subunit 10, putative K03357 APC10; anaphase-promoting complex subunit 10
C BRCC complex
D PKNH_0905000 DNA repair protein RAD51, putative K04482 RAD51; DNA repair protein RAD51
C KPC complex
C LUBAC complex
C CTLH complex
D PKNH_1269900 CTLH domain-containing protein, putative K18624 MAEA; macrophage erythroblast attacher
D PKNH_1264800 RanBPM and CLTH-like protein, putative K23338 GID8; glucose-induced degradation protein 8
C ERAD complex
C LMBR1L-GP78-UBAC2 complex
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
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ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D PKNH_1221300 ubiquitin carboxyl-terminal hydrolase isozyme L3, putative K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D PKNH_0914800 ubiquitin carboxyl-terminal hydrolase UCH54, putative K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D PKNH_0301300 ubiquitin specific protease, putative K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D PKNH_1016600 ubiquitin carboxyl-terminal hydrolase 2, putative K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D PKNH_0505500 ubiquitin carboxyl-terminal hydrolase 13, putative K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D PKNH_0211100 ubiquitin carboxyl-terminal hydrolase, putative K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D PKNH_1005500 ubiquitin carboxyl-terminal hydrolase 14, putative K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
C OTU
D PKNH_0939500 OTU domain-containing protein, putative K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
C MJD
D PKNH_1446200 uncharacterized protein K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D PKNH_0909600 Josephin domain-containing protein, putative K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D PKNH_1419900 uncharacterized protein K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D PKNH_1118900 conserved protein, unknown function K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
C JAMM
D PKNH_1103100 26S proteasome regulatory subunit RPN11, putative K03030 PSMD14; 26S proteasome regulatory subunit N11
C PPPDE
D PKNH_0805700 PPPDE peptidase, putative K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
C BRISC complex
B UBL-specific proteases (ULPs)
C PKNH_1453300 sentrin-specific protease 1, putative K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C PKNH_1221300 ubiquitin carboxyl-terminal hydrolase isozyme L3, putative K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C PKNH_1437500 PPPDE peptidase domain-containing protein, putative K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C COP9 signalosome (CSN) complex
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 5, 2024