+E Ubiquitin system KO
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Ubiquitin System - Phaeodactylum tricornutum
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C PHATRDRAFT_56440 hUbi; hypothetical protein K08770 UBC; ubiquitin C
C PHATRDRAFT_22043 UBI1/2; ubiquitin extension protein 1/2 K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C PHATRDRAFT_27118 UBI3; ubiquitin extension protein 3 K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C PHATRDRAFT_10769 hypothetical protein K02983 RP-S30e; small subunit ribosomal protein S30e
C PHATRDRAFT_50303 hypothetical protein K08341 GABARAP; GABA(A) receptor-associated protein
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C PHATRDRAFT_54754 hUba1; ubiquitin-activating enzyme E1, protein 2 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
C PHATRDRAFT_54460 UBA1; ubiquitin-activating enzyme E1, protein 1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C PHATRDRAFT_40111 hypothetical protein K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C PHATRDRAFT_44749 SAE2; sumo-activating enzyme 2 K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C PHATRDRAFT_33774 UBA3; ubiquitin-activating enzyme E1, protein 3 K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C PHATRDRAFT_15355 hypothetical protein K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C PHATRDRAFT_34373 hypothetical protein K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C PHATRDRAFT_9342 hypothetical protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C PHATRDRAFT_26750 hypothetical protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C PHATRDRAFT_22525 UBC2; ubiquitin conjugating enzyme E2 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C PHATRDRAFT_30092 hypothetical protein K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C PHATRDRAFT_28433 hypothetical protein K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C PHATRDRAFT_56437 hUbc6; hypothetical protein K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
C PHATRDRAFT_37077 hypothetical protein K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C PHATRDRAFT_30389 UBC1; ubiquitin-conjugating enzyme 1 K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C PHATRDRAFT_36198 hypothetical protein K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C PHATRDRAFT_48512 hypothetical protein K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C PHATRDRAFT_5608 hypothetical protein K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C PHATRDRAFT_47555 PAS2; hypothetical protein K10689 PEX4; peroxin-4 [EC:2.3.2.23]
B UBL-conjugating enzymes
C PHATRDRAFT_27762 hypothetical protein K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C PHATRDRAFT_48810 hypothetical protein K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C PHATRDRAFT_41667 hypothetical protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
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AUbiquitin ligases (E3)
B HECT type E3
C HECT type E3 associated proteins
B U-box type E3
C PHATRDRAFT_45922 hUfd2; hypothetical protein K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C PHATRDRAFT_27375 hypothetical protein K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C PHATRDRAFT_bd1638 hypothetical protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
B Single Ring-finger type E3
C BRE1 proteins
D PHATRDRAFT_50465 hypothetical protein K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
C SINA (Seven in absentia) proteins
C Ligand of Numb proteins
C March proteins
D PHATRDRAFT_42799 hypothetical protein K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
C MDM2/MDM4 proteins
C NFX1 proteins
C Pellino proteins
C Peripheral membrane proteins
D PHATRDRAFT_47516 hypothetical protein K13346 PEX10; peroxin-10
D PHATRDRAFT_49405 hypothetical protein K13345 PEX12; peroxin-12
C RBR proteins
D PHATRDRAFT_1905 hypothetical protein K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D PHATR_43899 hypothetical protein K11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]
C TRAF proteins
C TRIM/RBCC proteins
C UBR box proteins
C ATL proteins
C Other single Ring-finger type E3
D PHATRDRAFT_10102 hypothetical protein K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D PHATR_43819 hypothetical protein K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D PHATRDRAFT_5465 hypothetical protein K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D PHATRDRAFT_12877 hypothetical protein K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D PHATRDRAFT_14699 hypothetical protein K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D PHATRDRAFT_54121 sex comb extra K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D PHATRDRAFT_45524 hypothetical protein K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D PHATRDRAFT_45116 hypothetical protein K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D PHATRDRAFT_49801 hHrd1; hypothetical protein K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D PHATRDRAFT_48912 hypothetical protein K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D PHATRDRAFT_48146 hypothetical protein K23788 TUL1; transmembrane E3 ubiquitin-protein ligase [EC:2.3.2.27]
B Atypical E3
B UBL E3 ligases
C PHATRDRAFT_39090 Rbx1; hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C PHATRDRAFT_31997 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C PHATR_44171 hypothetical protein K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E PHATRDRAFT_39090 Rbx1; hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E PHATRDRAFT_29317 CUL1_3; CULlin protein 1 K03347 CUL1; cullin 1
D Adaptor protein
E PHATRDRAFT_17276 Skp1_1; hypothetical protein K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E PHATRDRAFT_42595 hypothetical protein K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E PHATRDRAFT_44342 hypothetical protein K10295 FBXO9; F-box protein 9
C Cul2 complex
D Ring finger protein
E PHATRDRAFT_39090 Rbx1; hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adoptor protein
E PHATRDRAFT_9649 hypothetical protein K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul3 complex
D Ring finger protein
E PHATRDRAFT_39090 Rbx1; hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E PHATRDRAFT_22367 CUL1_1; CULlin protein 3 K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
C Cul4 complex
D Ring finger protein
E PHATRDRAFT_39090 Rbx1; hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E PHATRDRAFT_44571 CUL1_2; CULlin protein 4 K10609 CUL4; cullin 4
D Adoptor protein
E PHATRDRAFT_29502 DDB1; damage-specific DNA binding protein 1 K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E PHATRDRAFT_47119 nucleotide-binding protein K10570 ERCC8; DNA excision repair protein ERCC-8
E PHATR_43884 hypothetical protein K11793 CRBN; cereblon
E PHATRDRAFT_21794 hypothetical protein K11805 DCAF7; DDB1- and CUL4-associated factor 7
E PHATR_44047 hypothetical protein K11806 DCAF13; DDB1- and CUL4-associated factor 13
E PHATRDRAFT_49529 hypothetical protein K24752 WDR70; WD repeat-containing protein 70
C Cul5 complex
D Ring finger protein
D Cullin
D Adoptor protein
E PHATRDRAFT_9649 hypothetical protein K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul7 complex
D Ring finger protein
E PHATRDRAFT_39090 Rbx1; hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E PHATRDRAFT_17276 Skp1_1; hypothetical protein K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E PHATRDRAFT_39090 Rbx1; hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E PHATRDRAFT_39090 Rbx1; hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
E PHATR_10271 APC11; hypothetical protein K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E PHATRDRAFT_47273 APC2; hypothetical protein K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E PHATRDRAFT_bd79 hypothetical protein K03363 CDC20; cell division cycle 20, cofactor of APC complex
E PHATRDRAFT_2648 CDH1; hypothetical protein K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E PHATRDRAFT_9475 APC3; hypothetical protein K03350 APC3; anaphase-promoting complex subunit 3
E PHATRDRAFT_1550 APC6; hypothetical protein K03353 APC6; anaphase-promoting complex subunit 6
E PHATRDRAFT_43701 APC7; hypothetical protein K03354 APC7; anaphase-promoting complex subunit 7
E PHATRDRAFT_38886 APC8; hypothetical protein K03355 APC8; anaphase-promoting complex subunit 8
E PHATRDRAFT_14899 APC10; hypothetical protein K03357 APC10; anaphase-promoting complex subunit 10
C BRCC complex
D PHATRDRAFT_54533 RAD51-g1; Rad51 DNA recombination/repair protein K04482 RAD51; DNA repair protein RAD51
C KPC complex
C LUBAC complex
C CTLH complex
D PHATRDRAFT_45060 hypothetical protein K23334 RANBP9_10; Ran-binding protein 9/10
C ERAD complex
C LMBR1L-GP78-UBAC2 complex
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D PHATRDRAFT_46608 hypothetical protein K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D PHATRDRAFT_43033 hypothetical protein K24350 UBXN7; UBX domain-containing protein 7
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ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D PHATRDRAFT_41928 hypothetical protein K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D PHATRDRAFT_3924 hypothetical protein K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D PHATRDRAFT_974 hypothetical protein K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D PHATRDRAFT_47704 hypothetical protein K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D PHATRDRAFT_18008 hypothetical protein K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D PHATR_3692 hypothetical protein K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D PHATRDRAFT_2936 hypothetical protein K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D PHATRDRAFT_12752 hypothetical protein K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D PHATRDRAFT_46080 hypothetical protein K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D PHATRDRAFT_29340 hypothetical protein K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D PHATRDRAFT_44745 hypothetical protein K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D PHATRDRAFT_42729 hypothetical protein K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
C OTU
D PHATRDRAFT_15239 hypothetical protein K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
D PHATRDRAFT_49012 hypothetical protein K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
C MJD
D PHATRDRAFT_47158 machado-joseph disease-like protein K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D PHATRDRAFT_13004 hypothetical protein K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D PHATRDRAFT_46063 hypothetical protein K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D PHATRDRAFT_42694 hypothetical protein K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
C JAMM
D PHATRDRAFT_20227 RPN11; regulatory proteasome non-atpase subunit 11 K03030 PSMD14; 26S proteasome regulatory subunit N11
C PPPDE
C ZUFSP
C BRISC complex
B UBL-specific proteases (ULPs)
C PHATRDRAFT_44664 hypothetical protein K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C PHATRDRAFT_41928 hypothetical protein K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C COP9 signalosome (CSN) complex
D PHATRDRAFT_54772 CSN1; COP9 SigNalosome subunit 1 K12175 GPS1; COP9 signalosome complex subunit 1
D PHATRDRAFT_28818 CSN2; COP9 SigNalosome subunit 2 K12176 COPS2; COP9 signalosome complex subunit 2
D PHATRDRAFT_21394 CSN4; COP9 SigNalosome subunit 4 K12178 COPS4; COP9 signalosome complex subunit 4
D PHATRDRAFT_43086 CSN5; COP9 SigNalosome subunit 5 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D PHATRDRAFT_46122 hypothetical protein K12179 COPS6; COP9 signalosome complex subunit 6
D PHATRDRAFT_52661 CSN7; COP9 SigNalosome subunit 7 K12180 COPS7; COP9 signalosome complex subunit 7
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 1, 2024