+F Repair protein KO
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DNA Repair and Recombination Proteins - Plasmodium vivax
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D PVX_080560 deoxyribodipyrimidine photolyase, putative K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E PVX_085700 uracil-DNA glycosylase, putative K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E PVX_117110 DNA-3-methyladenine glycosylase, putative K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E PVX_092090 A/G-specific adenine glycosylase, putative K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E PVX_113875 endonuclease III homologue, putative K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E PVX_082560 apurinic/apyrimidinic endonuclease Apn1, putative K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F PVX_001720 DNA polymerase delta catalytic subunit, putative K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F PVX_119520 DNA polymerase delta small subunit, putative K02328 POLD2; DNA polymerase delta subunit 2
E DNA polymerase epsilon complex
F PVX_114615 DNA polymerase epsilon, catalytic subunit a, putative K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F PVX_100665 hypothetical protein, conserved K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F PVX_201290 DNA polymerase epsilon subunit B, truncated, putative K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F PVX_206290 DNA polymerase epsilon subunit B, putative K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F PVX_208290 DNA polymerase epsilon subunit B, putative K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F PVX_200290 DNA polymerase epsilon subunit B K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
E PVX_115055 proliferating cell nuclear antigen, putative K04802 PCNA; proliferating cell nuclear antigen
E PVX_123960 proliferating cell nuclear antigen, putative K04802 PCNA; proliferating cell nuclear antigen
E PVX_000820 flap exonuclease, putative K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E PVX_122045 DNA ligase 1 precursor, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
E PVX_115115 bifunctional polynucleotide phosphatase/kinase, putative K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F PVX_094805 DNA repair protein RAD23, putative K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F PVX_095280 RING-box protein HRT1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E NER4 complex
F PVX_101435 DNA repair protein rhp16, putative K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F PVX_095320 DNA-directed RNA polymerase II largest subunit, putative K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F PVX_002755 DNA-directed RNA polymerase II 135 kDa polypeptide, putative K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F PVX_099560 DNA-directed RNA polymerase II, putative K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F PVX_003705 DNA-directed RNA polymerase II 16 kDa subunit, putative K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F PVX_115200 DNA-directed RNA polymerase II 23 kDa polypeptide, putative K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F PVX_119290 DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide, putative K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F PVX_111350 DNA-directed RNA polymerase II, putative K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F PVX_123375 RNA polymerase subunit 8c, putative K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F PVX_136260 DNA-directed RNA polymerase 2 subunit, truncated K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F PVX_087935 DNA-directed RNA polymerase II 8.2 kDa polypeptide, putative K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F PVX_122080 DNA-directed RNA polymerase II 13.3 kDa polypeptide, putative K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
E Cul4-CSA complex
F PVX_095280 RING-box protein HRT1, putative K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E Other TCR factor
F PVX_099155 hypothetical protein, conserved K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E PVX_110880 DNA repair helicase, putative K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E PVX_087010 DNA excision-repair helicase, putative K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E PVX_122565 transcription factor, putative K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E PVX_114665 hypothetical protein, conserved K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E PVX_101110 hypothetical protein, conserved K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E PVX_118395 REX1 DNA repair protein, putative K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E PVX_094935 cyclin dependent kinase 7 (cdk7), putative K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E PVX_117280 cyclin homologue, putative K06634 CCNH; cyclin H
E PVX_080625 CDK-activating kinase assembly factor, putative K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E PVX_000765 replication factor a protein, putative K07466 RFA1; replication factor A1
E PVX_118385 hypothetical protein, conserved K10740 RPA3; replication factor A3
D Other NER factors
E PVX_088055 DNA repair protein, putative K10847 XPA; DNA-repair protein complementing XP-A cells
E PVX_003600 ERCC1 nucleotide excision repair protein, putative K10849 ERCC1; DNA excision repair protein ERCC-1
E PVX_115400 DNA repair endonuclease, putative K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E PVX_003735 DNA repair endonuclease, putative K10846 ERCC5; DNA excision repair protein ERCC-5
E PVX_122045 DNA ligase 1 precursor, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E PVX_087875 DNA mismatch repair enzyme, putative K08735 MSH2; DNA mismatch repair protein MSH2
E PVX_085160 DNA mismatch repair enzyme, putative K08735 MSH2; DNA mismatch repair protein MSH2
E PVX_097835 DNA repair protein, putative K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E PVX_091525 DNA mismatch repair enzyme, putative K08734 MLH1; DNA mismatch repair protein MLH1
E PVX_081620 DNA mismatch repair protein PMS2, putative K10858 PMS2; DNA mismatch repair protein PMS2
D DNA polymerase delta complex
E PVX_001720 DNA polymerase delta catalytic subunit, putative K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E PVX_119520 DNA polymerase delta small subunit, putative K02328 POLD2; DNA polymerase delta subunit 2
D RPA (replication factor A)
E PVX_000765 replication factor a protein, putative K07466 RFA1; replication factor A1
E PVX_118385 hypothetical protein, conserved K10740 RPA3; replication factor A3
D RFC (replication factor C)
E PVX_002575 replication factor C subunit 1, putative K10754 RFC1; replication factor C subunit 1
E PVX_002640 replication factor C subunit 2, putative K10755 RFC2_4; replication factor C subunit 2/4
E PVX_100985 replication factor C subunit 4, putative K10755 RFC2_4; replication factor C subunit 2/4
E PVX_117300 replication factor C3, putative K10756 RFC3_5; replication factor C subunit 3/5
E PVX_091205 replication factor C subunit 5, putative K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E PVX_115055 proliferating cell nuclear antigen, putative K04802 PCNA; proliferating cell nuclear antigen
E PVX_123960 proliferating cell nuclear antigen, putative K04802 PCNA; proliferating cell nuclear antigen
E PVX_096090 hypothetical protein, conserved K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E PVX_122045 DNA ligase 1 precursor, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E PVX_081385 DNA repair exonuclease, putative K10865 MRE11; double-strand break repair protein MRE11
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
E PVX_081385 DNA repair exonuclease, putative K10865 MRE11; double-strand break repair protein MRE11
D BRCA complex
E PVX_091045 DNA repair protein RAD51, putative K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E PVX_091045 DNA repair protein RAD51, putative K04482 RAD51; DNA repair protein RAD51
D Rad52 family proteins
D Rad54 family proteins
E PVX_093575 DNA repair protein rhp54, putative K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
E PVX_083255 DNA topoisomerase III alpha, putative K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D RPA (replication factor A)
E PVX_000765 replication factor a protein, putative K07466 RFA1; replication factor A1
E PVX_118385 hypothetical protein, conserved K10740 RPA3; replication factor A3
D Protein phosphatase 4
E PVX_099825 serine/threonine protein phosphatase, putative K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
D AP-5 complex
E PVX_094610 hypothetical protein K19024 AP5S1; AP-5 complex subunit sigma-1
D SMC5-SMC6 complex
E PVX_091805 SMC family, C-terminal domain containing protein K22803 SMC5; structural maintenance of chromosomes protein 5
E PVX_079985 hypothetical protein, conserved K22804 SMC6; structural maintenance of chromosomes protein 6
E PVX_115375 hypothetical protein, conserved K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E PVX_117915 hypothetical protein, conserved K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
D Other HR factors
E PVX_096255 hypothetical protein, conserved K10881 SHFM1; 26 proteasome complex subunit DSS1
E PVX_100900 HD domain containing protein K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E PVX_000850 AAA family ATPase, putative K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E PVX_094690 hypothetical protein, conserved K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
E PVX_081385 DNA repair exonuclease, putative K10865 MRE11; double-strand break repair protein MRE11
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
E PVX_083255 DNA topoisomerase III alpha, putative K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
E PVX_091045 DNA repair protein RAD51, putative K04482 RAD51; DNA repair protein RAD51
C Other DSBR factors
D Protein phosphatase 6
E PVX_119815 serine/threonine protein phosphatase, putative K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
D Ubiquitin ligases
D Others
E PVX_117105 hypothetical protein, conserved K23314 WRAP53; telomerase Cajal body protein 1
E PVX_111050 WD domain, G-beta repeat domain containing protein K24752 WDR70; WD repeat-containing protein 70
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
D PVX_123140 ubiquitin-conjugating enzyme E2, putative K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D PVX_095270 ubiquitin-conjugating enzyme E2, putative K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
D PVX_083065 hypothetical protein, conserved K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
D PVX_119410 ubiquitin-conjugating enzyme E2, putative K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D PVX_079885 ubiquitin-conjugating enzyme E2, putative K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D PVX_115055 proliferating cell nuclear antigen, putative K04802 PCNA; proliferating cell nuclear antigen
D PVX_123960 proliferating cell nuclear antigen, putative K04802 PCNA; proliferating cell nuclear antigen
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
D PVX_002640 replication factor C subunit 2, putative K10755 RFC2_4; replication factor C subunit 2/4
D PVX_100985 replication factor C subunit 4, putative K10755 RFC2_4; replication factor C subunit 2/4
D PVX_117300 replication factor C3, putative K10756 RFC3_5; replication factor C subunit 3/5
D PVX_091205 replication factor C subunit 5, putative K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
D PVX_118565 hypothetical protein, conserved K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D PVX_115063 hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon
D PVX_089505 suppressor of Ras1 3-9, putative K06630 YWHAE; 14-3-3 protein epsilon
D PVX_117590 ATPase, putative K12196 VPS4; vacuolar protein-sorting-associated protein 4
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
D PVX_117530 hypothetical protein, conserved K17815 EXO5; exonuclease V [EC:3.1.-.-]
C Helicases
C PSO4 complex
D PVX_119545 WD domain, G-beta repeat domain containing protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D PVX_111045 DNA binding protein Myb2, putative K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D PVX_113855 hypothetical protein, conserved K12861 BCAS2; pre-mRNA-splicing factor SPF27
D PVX_119245 splicing regulatory protein, putative K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D PVX_091970 deoxyuridine 5'-triphosphate nucleotidohydrolase, putative K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D PVX_084685 ribonucleoside-diphosphate reductase large chain, putative K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D PVX_095010 ribonucleotide reductase small subunit, putative K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D PVX_086155 ribonucleoside-diphosphate reductase small chain, putative K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D PVX_080560 deoxyribodipyrimidine photolyase, putative K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E PVX_085700 uracil-DNA glycosylase, putative K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E PVX_117110 DNA-3-methyladenine glycosylase, putative K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E PVX_092090 A/G-specific adenine glycosylase, putative K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E PVX_113875 endonuclease III homologue, putative K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E PVX_080535 UvrD/REP helicase, putative K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F PVX_116845 DNA-directed RNA polymerase, alpha subunit, putative K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F PVX_122210 hypothetical protein, conserved K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E PVX_080535 UvrD/REP helicase, putative K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PVX_098000 single-strand binding protein, putative K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F PVX_123795 DNA GyrAse a-subunit, putative K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F PVX_100925 DNA gyrase subunit b, putative K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D PVX_098000 single-strand binding protein, putative K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D PVX_091970 deoxyuridine 5'-triphosphate nucleotidohydrolase, putative K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024