+F Repair protein KO #

  DNA Repair and Recombination Proteins - Rubrobacter xylanophilus

% ! AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D Rxyl_0663 Deoxyribodipyrimidine photo-lyase type II K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E Rxyl_1309 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E Rxyl_2229 HhH-GPD K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E Rxyl_2676 DNA-(apurinic or apyrimidinic site) lyase / endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D Long Patch-BER factors E DNA polymerase delta complex E DNA polymerase epsilon complex D Short Patch-BER factors D Other BER factors C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex E Cul4-DDB2 complex E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex E Cul4-CSA complex E Other TCR factor D TFIIH complex D RPA (replication factor A) D Other NER factors C MMR (mismatch excision repair) D Mismatch and loop recognition factors D MutL homologs D DNA polymerase delta complex D RPA (replication factor A) D RFC (replication factor C) D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex D BRCA1-C complex D BRCA complex D RecA family proteins D Rad52 family proteins D Rad54 family proteins D RecQ family DNA helicases D Bloom's syndrome complex (BTR) D RPA (replication factor A) D Protein phosphatase 4 D AP-5 complex D SMC5-SMC6 complex D Other HR factors C NHEJ (non-homologous end-joining) D DNA-PK complex D MRX complex D DNA Ligase 4 complex D X-family DNA polymerases D Other NHEJ factors C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) D FANCD2-I complex D Downstream FA components D Other FA pathway factors C Other DSBR factors D Protein phosphatase 6 D Ubiquitin ligases D Others B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group C Other TLS factors B Check point factors C Rad9-Hus1-Rad1 complex C HRAD17(Rad24)-RFC complex C Rad17-Mec3-Ddc1 complex C FPC (fork protection complex) C Triple T complex C BAG6-UBL4A-GET4 complex C Other check point factors B Other factors with a suspected DNA repair function C DNA polymerases C Nucleases C Helicases C PSO4 complex C Modulation of nucleotide pools D Rxyl_0700 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Rxyl_2554 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Rxyl_2787 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Rxyl_2622 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D Rxyl_0663 Deoxyribodipyrimidine photo-lyase type II K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E Rxyl_0808 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] E Rxyl_0503 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] E Rxyl_2949 Uracil-DNA glycosylase superfamily K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] E Rxyl_1787 Uracil-DNA glycosylase superfamily K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] E Rxyl_1215 DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21] E Rxyl_1309 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E Rxyl_2229 HhH-GPD K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E Rxyl_1786 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E Rxyl_2433 Formamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E Rxyl_2550 DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E Rxyl_2676 DNA-(apurinic or apyrimidinic site) lyase / endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E Rxyl_1147 Endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] E Rxyl_2425 Endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7] D RecJ E Rxyl_0888 phosphoesterase, RecJ-like protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D DNA ligase E Rxyl_0327 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D DNA polymerase I E Rxyl_2025 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] C NER (nucleotide excision repair) D GGR (global genome repair) factors E Rxyl_2016 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A E Rxyl_2021 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B E Rxyl_2010 Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C E Rxyl_0825 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E Rxyl_2025 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] E Rxyl_0327 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) F Rxyl_2162 DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] F Rxyl_2161 DNA-directed RNA polymerase, subunit beta-prime K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] F Rxyl_2128 DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] F Rxyl_1472 DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] E TRCF (transcription-repair coupling factor) F Rxyl_0909 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] C MMR (mismatch excision repair) D Mismatch and loop recognition factors E Rxyl_0292 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS D Molecular matchmaker E Rxyl_0293 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL E Rxyl_0034 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL D Strand discrimination factor D DNA exonucleases D DNA polymerase III holoenzyme E Rxyl_1096 DNA polymerase III catalytic subunit, DnaE type K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E Rxyl_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E Rxyl_1518 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E Rxyl_1961 DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E Rxyl_2984 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E Rxyl_2444 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D DNA ligase E Rxyl_0327 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Other MMR factors E Rxyl_0825 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E Rxyl_0045 single-strand binding protein K03111 ssb; single-strand DNA-binding protein E Rxyl_1835 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins E Rxyl_1423 RecA protein K03553 recA; recombination protein RecA E Rxyl_1323 Holliday junction DNA helicase subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA E Rxyl_1324 Holliday junction DNA helicase subunit RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E Rxyl_1322 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] E Rxyl_1469 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] E Rxyl_0448 SMC protein-like protein K03546 sbcC; DNA repair protein SbcC/Rad50 E Rxyl_0449 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11 D RecFOR pathway proteins E Rxyl_1423 RecA protein K03553 recA; recombination protein RecA E Rxyl_2178 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms E Rxyl_0004 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF E Rxyl_1371 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] E Rxyl_0888 phosphoesterase, RecJ-like protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] E Rxyl_1504 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) E Rxyl_0510 DNA replication and repair protein RecR K06187 recR; recombination protein RecR E Rxyl_1453 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) E Rxyl_1323 Holliday junction DNA helicase subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA E Rxyl_1324 Holliday junction DNA helicase subunit RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E Rxyl_1322 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D AddAB pathway proteins D Other HR factor E Rxyl_0257 CRISPR-associated protein, Cas1 family K15342 cas1; CRISP-associated protein Cas1 D Archaeal homologous recombinant proteins E Rxyl_0448 SMC protein-like protein K03546 sbcC; DNA repair protein SbcC/Rad50 E Rxyl_0449 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11 C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F Rxyl_0006 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F Rxyl_0005 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F Rxyl_1964 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] E Supressor F Rxyl_2301 bacterial nucleoid protein Hbs K03530 hupB; DNA-binding protein HU-beta D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway F Rxyl_0888 phosphoesterase, RecJ-like protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] F Rxyl_1504 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) F Rxyl_0510 DNA replication and repair protein RecR K06187 recR; recombination protein RecR F Rxyl_0327 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E Facilitator E Supressor F Rxyl_2016 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A F Rxyl_2021 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C Other SOS response factors D Rxyl_1423 RecA protein K03553 recA; recombination protein RecA D Rxyl_1918 SOS-response transcriptional repressor, LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D Rxyl_1453 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) D Rxyl_1922 DNA polymerase III, alpha subunit K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7] D Rxyl_0045 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Rxyl_1424 regulatory protein RecX K03565 recX; regulatory protein B Other factors with a suspected DNA repair function C DNA polymerase D Rxyl_0486 PHP-like protein K02347 polX; DNA polymerase (family X) D Rxyl_0230 PHP-like protein K02347 polX; DNA polymerase (family X) C DNA helicases C Modulation of nucleotide pools D Rxyl_0700 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Rxyl_2554 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Rxyl_2787 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Rxyl_2622 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D Rxyl_2874 Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] C Others D Rxyl_1414 phosphoesterase, RecJ-like protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024