+F Repair protein KO
#
DNA Repair and Recombination Proteins - Rubrobacter xylanophilus
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Rxyl_0663 Deoxyribodipyrimidine photo-lyase type II K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E Rxyl_1309 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E Rxyl_2229 HhH-GPD K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Rxyl_2676 DNA-(apurinic or apyrimidinic site) lyase / endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D Rxyl_0700 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Rxyl_2554 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Rxyl_2787 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Rxyl_2622 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Rxyl_0663 Deoxyribodipyrimidine photo-lyase type II K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E Rxyl_0808 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Rxyl_0503 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Rxyl_2949 Uracil-DNA glycosylase superfamily K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Rxyl_1787 Uracil-DNA glycosylase superfamily K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Rxyl_1215 DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E Rxyl_1309 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E Rxyl_2229 HhH-GPD K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Rxyl_1786 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Rxyl_2433 Formamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Rxyl_2550 DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Rxyl_2676 DNA-(apurinic or apyrimidinic site) lyase / endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Rxyl_1147 Endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E Rxyl_2425 Endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E Rxyl_0888 phosphoesterase, RecJ-like protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E Rxyl_0327 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E Rxyl_2025 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E Rxyl_2016 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E Rxyl_2021 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E Rxyl_2010 Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E Rxyl_0825 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Rxyl_2025 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E Rxyl_0327 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F Rxyl_2162 DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F Rxyl_2161 DNA-directed RNA polymerase, subunit beta-prime K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F Rxyl_2128 DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F Rxyl_1472 DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F Rxyl_0909 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E Rxyl_0292 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E Rxyl_0293 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
E Rxyl_0034 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
E Rxyl_1096 DNA polymerase III catalytic subunit, DnaE type K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E Rxyl_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E Rxyl_1518 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E Rxyl_1961 DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E Rxyl_2984 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Rxyl_2444 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E Rxyl_0327 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E Rxyl_0825 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Rxyl_0045 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E Rxyl_1835 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E Rxyl_1423 RecA protein K03553 recA; recombination protein RecA
E Rxyl_1323 Holliday junction DNA helicase subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Rxyl_1324 Holliday junction DNA helicase subunit RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Rxyl_1322 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E Rxyl_1469 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E Rxyl_0448 SMC protein-like protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Rxyl_0449 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E Rxyl_1423 RecA protein K03553 recA; recombination protein RecA
E Rxyl_2178 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E Rxyl_0004 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E Rxyl_1371 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Rxyl_0888 phosphoesterase, RecJ-like protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E Rxyl_1504 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E Rxyl_0510 DNA replication and repair protein RecR K06187 recR; recombination protein RecR
E Rxyl_1453 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E Rxyl_1323 Holliday junction DNA helicase subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Rxyl_1324 Holliday junction DNA helicase subunit RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Rxyl_1322 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E Rxyl_0257 CRISPR-associated protein, Cas1 family K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E Rxyl_0448 SMC protein-like protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Rxyl_0449 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F Rxyl_0006 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F Rxyl_0005 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F Rxyl_1964 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F Rxyl_2301 bacterial nucleoid protein Hbs K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F Rxyl_0888 phosphoesterase, RecJ-like protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F Rxyl_1504 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F Rxyl_0510 DNA replication and repair protein RecR K06187 recR; recombination protein RecR
F Rxyl_0327 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F Rxyl_2016 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F Rxyl_2021 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D Rxyl_1423 RecA protein K03553 recA; recombination protein RecA
D Rxyl_1918 SOS-response transcriptional repressor, LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D Rxyl_1453 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D Rxyl_1922 DNA polymerase III, alpha subunit K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D Rxyl_0045 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D Rxyl_1424 regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D Rxyl_0486 PHP-like protein K02347 polX; DNA polymerase (family X)
D Rxyl_0230 PHP-like protein K02347 polX; DNA polymerase (family X)
C DNA helicases
C Modulation of nucleotide pools
D Rxyl_0700 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Rxyl_2554 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Rxyl_2787 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Rxyl_2622 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Rxyl_2874 Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C Others
D Rxyl_1414 phosphoesterase, RecJ-like protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024