+C Peptidoglycan biosynthesis and degradation proteins KO
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Peptidoglycan Biosynthesis and Degradation Proteins - Staphylococcus aureus subsp. aureus MRSA252 (MRSA)
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APrecursor biosynthesis
B Transferase/Dehydrogenase
C SAR2188 murA1; putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
C SAR2212 murA2; putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
C SAR0792 murB; putative UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
B Amino acid ligase
C SAR1818 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
C SAR1159 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
C SAR0988 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia minopimelate ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7]
C SAR2170 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
C SAR2346 fmhB; putative peptidoglycan pentaglycine interpeptide biosynthesis protein K11693 femX; peptidoglycan pentaglycine glycine transferase (the first glycine) [EC:2.3.2.16]
C SAR1387 femA; factor essential for expression of methicillin resistance K11694 femA; peptidoglycan pentaglycine glycine transferase (the second and third glycine) [EC:2.3.2.17]
C SAR1388 femB; putative methicillin resistance expression factor K11695 femB; peptidoglycan pentaglycine glycine transferase (the fourth and fifth glycine) [EC:2.3.2.18]
B Racemase
C SAR1411 dal; putative alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
C SAR2158 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
C SAR1123 murI; putative glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
B Carboxypeptidase
B Glycosyltransferase
C SAR1158 mraY; phospho-N-acetylmuramoyl-pentapeptide-transfera se K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
C SAR1430 murG; putative UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyr ophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
B Diphosphatase
C SAR0736 bacA; putative undecaprenol kinase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
C SAR1429 putative membrane protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]
B Flippase
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APeptidoglycan biosynthesis and degradation
B Glycosyltransferase/DD-Transpeptidase (Class A PBP)
C SAR1461 pbp2; penicillin-binding protein 2 K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
B DD-Transpeptidase (Class B PBP)
C SAR0039 mecA; penicillin-binding protein 2 prime K02545 mecA; penicillin-binding protein 2 prime [EC:3.4.16.4]
C SAR1157 pbpA; penicillin-binding protein 1 K12552 pbpA; penicillin-binding protein 1 [EC:3.4.-.-]
C SAR1629 pbpF; penicillin-binding protein PBP2B K12553 pbp3; penicillin-binding protein 3 [EC:3.4.-.-]
B DD-Carboxypeptidase/DD-Endopeptidase (Low molecular weight PBP)
C SAR0652 pbp4; penicillin-binding protein 4 K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
B Glycosyltransferase
C SAR1807 putative transglycosylase K12551 sgtA; monofunctional glycosyltransferase [EC:2.4.99.28]
C SAR1964 putative transglycosylase K04478 sgtB; monofunctional glycosyltransferase [EC:2.4.99.28]
B Transpeptidase
B Carboxypeptidase
B Endopeptidase
C SAR1290 putative exported protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
C SAR0204 putative peptidase K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-]
C SAR0273 lytM; peptidoglycan hydrolase K08259 lytM; lysostaphin [EC:3.4.24.75]
B Sortase
C SAR2608 srtA; sortase A K07284 srtA; sortase A [EC:3.4.22.70]
C SAR1108 srtB; sortase B K08600 srtB; sortase B [EC:3.4.22.71]
B Lytic transglycosylase
B Amidase
B Structural protein
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: January 30, 2024