+E Replication protein KO
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DNA Replication Proteins - Staphylococcus aureus subsp. aureus MRSA252 (MRSA)
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
C CDK (cyclin dependent kinase)
C DDK (Dbf-4 dependent kinase)
C GINS complex
C Other initiation factors
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
C DNA polymerase epsilon complex
C DNA polymerase delta complex
C DNA polymerase gamma complex (mitochondrial)
C RPA (replication protein A)
C RFC (replication factor C)
C RNase H
D SAR1446 conserved hypothetical protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
C Other elongation factors
B DNA Replication Termination Factors
C DNA methylation enzymes
C Prevention of re-replication factors
C Telomere proteins
D Shelterin complex
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D Dyskerin complex
C Telomerase complex (fungi)
D Sm core complex
C ELG1-RFC complex
C MRN complex
C Other termination factors
B DNA Topoisomerases
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D SAR1482 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SAR0001 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D SAR0016 dnaC; DnaB-like helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D SAR1639 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D SAR1764 dnaB; chromosome replication initiation/membrane attachment protein K03346 dnaB; replication initiation and membrane attachment protein
D SAR1763 dnaI; putative primosomal protein K11144 dnaI; primosomal protein DnaI
D SAR2083 putative single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SAR0363 ssb; putative single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SAR2185 putative single strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
E SAR1781 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SAR1240 polC; DNA polymerase III PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E SAR0002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SAR1664 conserved hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E SAR0485 holB; putative DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E SAR1985 putative exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SAR0477 dnaX; DNA polymerase III, tau subunit K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RNase H
E SAR1446 conserved hypothetical protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E SAR1220 rnhB; putative ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
E SAR1113 putative ribonuclease K03471 rnhC; ribonuclease HIII [EC:3.1.26.4]
D Other elongation factors
E SAR1769 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E SAR1996 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E SAR1452 putative 5'-3' exonuclease K23786 exoA; 5'-3' exonuclease [EC:3.1.11.-]
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E SAR1446 conserved hypothetical protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E SAR1220 rnhB; putative ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
C SAR0006 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
C SAR0005 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
C SAR1367 grlA; topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
C SAR1366 grlB; topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
C SAR1226 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C SAR2339 putative DNA topoisomerase K03169 topB; DNA topoisomerase III [EC:5.6.2.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022