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Mitochondrial Biogenesis - Saccharomyces cerevisiae (budding yeast)
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AMitochondrial DNA transcription, translation, and replication factors
B Mitochondrial DNA-encoded proteins
C Mitochondrial respiratory chain complex I
C Mitochondrial respiratory chain complex III
D Q0105 COB; cytochrome b K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D Q0115 BI3; cytochrome b mRNA maturase bI3 K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D Q0110 BI2; cytochrome b mRNA maturase bI2 K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D Q0120 BI4; intron-encoded RNA maturase bI4 K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
C Cytochrome c oxidase
D Q0045 COX1; cytochrome c oxidase subunit 1 K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
D Q0250 COX2; cytochrome c oxidase subunit 2 K02261 COX2; cytochrome c oxidase subunit 2
D Q0275 COX3; cytochrome c oxidase subunit 3 K02262 COX3; cytochrome c oxidase subunit 3
C F-type ATPase
D Q0080 ATP8; F1F0 ATP synthase subunit 8 K02125 ATPeF08; F-type H+-transporting ATPase subunit 8
D Q0085 ATP6; F1F0 ATP synthase subunit A K02126 ATPeF0A; F-type H+-transporting ATPase subunit a
B Mitochondrial transcription and translation factors
C Mitochondrial RNA polymerase
D YFL036W RPO41; DNA-directed RNA polymerase K10908 POLRMT; DNA-directed RNA polymerase, mitochondrial [EC:2.7.7.6]
C Mitochondrial transcription factors
C Mitochondrial translation factors
D YOL023W IFM1; translation initiation factor 2 K02519 infB; translation initiation factor IF-2
D YOR187W TUF1; translation elongation factor Tu K02358 tuf; elongation factor Tu
D YJL102W MEF2; Mef2p K02355 fusA; elongation factor G
D YLR069C MEF1; Mef1p K02355 fusA; elongation factor G
D YLR289W GUF1; GTPase GUF1 K21594 GUF1; translation factor GUF1, mitochondrial [EC:3.6.5.-]
C RNase MRP
D YNL221C POP1; ribonuclease P/MRP protein subunit POP1 K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D YNL282W POP3; Pop3p K14522 POP3; ribonuclease P/MRP protein subunit POP3 [EC:3.1.26.5]
D YBR257W POP4; RNase P/RNase MRP complex subunit K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D YAL033W POP5; RNA-binding protein POP5 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D YGR030C POP6; ribonuclease P/MRP protein subunit POP6 K14524 POP6; ribonuclease P/MRP protein subunit POP6 [EC:3.1.26.5]
D YBR167C POP7; ribonuclease P/MRP protein subunit POP7 K14526 POP7; ribonuclease P/MRP protein subunit POP7 [EC:3.1.26.5]
D YBL018C POP8; ribonuclease P K14528 POP8; ribonuclease P/MRP protein subunit POP8 [EC:3.1.26.5]
D YHR062C RPP1; RNA-binding RNA processing protein RPP1 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D YDR478W SNM1; Snm1p K14531 SNM1; ribonuclease MRP protein subunit SNM1
C Mitochondrial ribonuclease P
D YML091C RPM2; ribonuclease P K14533 RPM2; ribonuclease P protein component, mitochondrial [EC:3.1.26.5]
C Other mitochondrial DNA transcription and translation factors
D YLR203C MSS51; Mss51p K17656 MSS51; mitochondrial splicing suppressor protein 51
D YIR021W MRS1; Mrs1p K17657 MRS1; mitochondrial RNA-splicing protein MRS1
D YJL209W CBP1; Cbp1p K17660 CBP1; cytochrome b pre-mRNA-processing protein 1
D YHL038C CBP2; Cbp2p K17661 CBP2; cytochrome b pre-mRNA-processing protein 2
D YPL215W CBP3; Cbp3p K17662 CBP3; cytochrome b pre-mRNA-processing protein 3
D YBR120C CBP6; Cbp6p K17663 CBP6; cytochrome b pre-mRNA-processing protein 6
D YDL069C CBS1; Cbs1p K17664 CBS1; cytochrome b translational activator protein CBS1, mitochondrial
D YDR197W CBS2; Cbs2p K17665 CBS2; cytochrome b translational activator protein CBS2, mitochondrial
D YGR222W PET54; Pet54p K17666 PET54; protein PET54, mitochondrial
D YMR257C PET111; Pet111p K17667 PET111; protein PET111, mitochondrial
D YER153C PET122; Pet122p K17668 PET122; protein PET122, mitochondrial
D YLR067C PET309; Pet309p K17669 PET309; pentatricopeptide repeat-containing protein PET309
D YNR045W PET494; Pet494p K17670 PET494; COX3 mRNA-specific translational activator PET494
D YMR064W AEP1; Aep1p K17671 AEP1; ATPase expression protein 1, mitochondrial
D YMR282C AEP2; Aep2p K17672 AEP2; ATPase expression protein 2, mitochondrial
D YPL005W AEP3; Aep3p K18155 AEP3; ATPase expression protein 3, mitochondrial
D YEL052W AFG1; Afg1p K18798 AFG1; peroxisome-assembly ATPase [EC:3.6.4.7]
D YDR350C ATP22; Atp22p K17673 ATP22; mitochondrial translation factor ATP22
D YNR020C ATP23; putative metalloprotease K18156 ATP23; mitochondrial inner membrane protease ATP23 [EC:3.4.24.-]
D YMR066W SOV1; Sov1p K17674 SOV1; protein SOV1, mitochondrial
D YPL029W SUV3; ATP-dependent RNA helicase SUV3 K17675 SUPV3L1; ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:5.6.2.6]
D YMR287C DSS1; exoribonuclease II K19782 DSS1; exoribonuclease II, mitochondrial [EC:3.1.13.1]
D YBL030C PET9; ADP/ATP carrier protein PET9 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D YBR085W AAC3; ADP/ATP carrier protein AAC3 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D YMR056C AAC1; ADP/ATP carrier protein AAC1 K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
D YKR052C MRS4; Fe(2+) transporter K15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28/37
D YJL133W MRS3; Fe(2+) transporter K15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28/37
D YPL097W MSY1; tyrosine--tRNA ligase MSY1 K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D YGR185C TYS1; tyrosine--tRNA ligase TYS1 K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D YPL160W CDC60; leucine--tRNA ligase CDC60 K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D YLR382C NAM2; leucine--tRNA ligase NAM2 K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D YPL104W MSD1; aspartate--tRNA ligase MSD1 K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D YPR081C GRS2; putative glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D YBR121C GRS1; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D YHR091C MSR1; arginine--tRNA ligase MSR1 K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D YDR341C RRS1; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D YMR293C HER2; glutamyl-tRNA(Gln) amidotransferase subunit HER2 K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D YBL080C PET112; glutamyl-tRNA(Gln) amidotransferase subunit PET112 K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D YMR097C MTG1; putative GTPase MTG1 K19828 MTG1; mitochondrial GTPase 1
D YGL063W PUS2; pseudouridine synthase PUS2 K15452 PUS2; mitochondrial tRNA pseudouridine27/28 synthase [EC:5.4.99.44]
D YLR281C RSO55; Rso55p K23498 COXPD7; peptide chain release factor
D YDR282C MRX10; Mrx10p K23499 RMND1; required for meiotic nuclear division protein 1
D YER156C MYG1; Myg1p K25877 MYG1; MYG1 exonuclease [EC:3.1.-.-]
B Mitochondrial DNA replication factors
C Mitochondrial DNA polymerase
D YOR330C MIP1; DNA-directed DNA polymerase gamma MIP1 K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
C Mitochondrial DNA maintenance factors
D YKL011C CCE1; cruciform cutting endonuclease K17676 CCE1; cruciform cutting endonuclease 1 [EC:3.1.21.10]
D YJL208C NUC1; ribonuclease K01173 ENDOG; endonuclease G, mitochondrial
D YDR332W IRC3; double-stranded DNA-dependent ATPase K17677 IRC3; ATP-dependent helicase IRC3 [EC:5.6.2.-]
D YGL064C MRH4; ATP-dependent RNA helicase K17678 MRH4; ATP-dependent RNA helicase MRH4, mitochondrial [EC:5.6.2.7]
D YDR194C MSS116; ATP-dependent RNA helicase K17679 MSS116; ATP-dependent RNA helicase MSS116, mitochondrial [EC:5.6.2.7]
D YHR031C RRM3; DNA helicase K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D YML061C PIF1; DNA helicase PIF1 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D YOL095C HMI1; ATP-dependent 3'-5' DNA helicase K19781 HMI1; ATP-dependent DNA helicase HMI1, mitochondrial [EC:5.6.2.4]
C Other Mitochondrial DNA replication factors
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AMitochondrial protein import machinery
B Endoplasmic reticulum membrane and cytosol
C ER-mitochondria encounter structure (ERMES) complex
D YLL006W MMM1; ERMES complex subunit MMM1 K17764 MMM1; maintenance of mitochondrial morphology protein 1
D YOL009C MDM12; ERMES complex subunit MDM12 K17765 MDM12; mitochondrial distribution and morphology protein 12
C Other ER-memrane and cytosol factors
D YNL064C YDJ1; type I HSP40 co-chaperone YDJ1 K09503 DNAJA2; DnaJ homolog subfamily A member 2
D YLR090W XDJ1; Xdj1p K09503 DNAJA2; DnaJ homolog subfamily A member 2
D YNL077W APJ1; Apj1p K09503 DNAJA2; DnaJ homolog subfamily A member 2
D YAL048C GEM1; ERMES complex Ca(2+)-binding regulatory GTPase GEM1 K07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
D YLL024C SSA2; Hsp70 family chaperone SSA2 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D YAL005C SSA1; Hsp70 family ATPase SSA1 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D YER103W SSA4; Hsp70 family chaperone SSA4 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D YBL075C SSA3; Hsp70 family ATPase SSA3 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D YNL209W SSB2; Hsp70 family ATPase SSB2 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D YDL229W SSB1; Hsp70 family ATPase SSB1 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
B Outer membrane
C Transporter outer membrane (TOM) complex
D YMR203W TOM40; Tom40p K11518 TOM40; mitochondrial import receptor subunit TOM40
D YHR117W TOM71; protein channel TOM71 K17768 TOM70; mitochondrial import receptor subunit TOM70
D YNL121C TOM70; protein channel TOM70 K17768 TOM70; mitochondrial import receptor subunit TOM70
D YNL131W TOM22; Tom22p K17769 TOM22; mitochondrial import receptor subunit TOM22
D YGR082W TOM20; Tom20p K17770 TOM20; mitochondrial import receptor subunit TOM20
D YNL070W TOM7; Tom7p K17771 TOM7; mitochondrial import receptor subunit TOM7
D YOR045W TOM6; Tom6p K17772 TOM6; mitochondrial import receptor subunit TOM6
D YPR133W-A TOM5; Tom5p K17773 TOM5; mitochondrial import receptor subunit TOM5
C TOB/SAM complex
D YNL026W SAM50; SAM complex subunit SAM50 K07277 SAM50; outer membrane protein insertion porin family
D YMR060C SAM37; SAM complex subunit SAM37 K17714 SAM37; sorting and assembly machinery component 37
D YHR083W SAM35; SAM complex subunit SAM35 K17715 SAM35; sorting and assembly machinery component 35
C Porin
D YNL055C POR1; porin POR1 K15040 VDAC2; voltage-dependent anion channel protein 2
D YIL114C POR2; putative porin POR2 K15040 VDAC2; voltage-dependent anion channel protein 2
C ERMES complex
D YAL010C MDM10; Mdm10p K17774 MDM10; mitochondrial distribution and morphology protein 10
D YGL219C MDM34; ERMES complex subunit MDM34 K17775 MDM34; mitochondrial distribution and morphology protein 34
C Other outer membrane factor
B Inter membrane space
C Transporter inner membrane (TIM) 9/10 complex
D YEL020W-A TIM9; protein transporter TIM9 K17777 TIM9; mitochondrial import inner membrane translocase subunit TIM9
D YHR005C-A TIM10; protein transporter TIM10 K17778 TIM10; mitochondrial import inner membrane translocase subunit TIM10
C TIM8/13 complex
D YJR135W-A TIM8; protein transporter TIM8 K17780 TIM8; mitochondrial import inner membrane translocase subunit TIM8
D YGR181W TIM13; protein translocase subunit TIM13 K17781 TIM13; mitochondrial import inner membrane translocase subunit TIM13
C Mitochondrial intermembrane space assembly (MIA) complex
D YKL195W MIA40; Mia40p K17782 MIA40; mitochondrial intermembrane space import and assembly protein 40
D YGR029W ERV1; flavin-linked sulfhydryl oxidase K17783 ERV1; mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2]
B Inner mambrane
C MICOS complex
D YCL057C-A MIC10; Mic10p K17784 MICOS10; MICOS complex subunit MIC10
D YKR016W MIC60; Mic60p K17785 IMMT; MICOS complex subunit MIC60
C MICOS complex (yeast)
D YCL057C-A MIC10; Mic10p K17784 MICOS10; MICOS complex subunit MIC10
D YKR016W MIC60; Mic60p K17785 IMMT; MICOS complex subunit MIC60
D YBR262C MIC12; Mic12p K17787 MIC12; MICOS complex subunit MIC12
D YFR011C MIC19; Mic19p K17788 MIC19; MICOS complex subunit MIC19
D YGR235C MIC26; Mic26p K17786 MIC26; MICOS complex subunit MIC26
D YNL100W MIC27; Mic27p K17789 MIC27; MICOS complex subunit MIC27
C TIM22 complex
D YDL217C TIM22; translocation channel protein TIM22 K17790 TIM22; mitochondrial import inner membrane translocase subunit TIM22
D YOR297C TIM18; Tim18p K17791 TIM18; mitochondrial import inner membrane translocase subunit TIM18
D YJL054W TIM54; Tim54p K17792 TIM54; mitochondrial import inner membrane translocase subunit TIM54
D YBR091C TIM12; Tim12p K17793 TIM12; mitochondrial import inner membrane translocase subunit TIM12
C TIM23 complex
D YNR017W TIM23; protein transporter TIM23 K17794 TIM23; mitochondrial import inner membrane translocase subunit TIM23
D YJL143W TIM17; protein transporter TIM17 K17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17
D YGR033C TIM21; Tim21p K17796 TIM21; mitochondrial import inner membrane translocase subunit TIM21
D YPL063W TIM50; protein translocase subunit TIM50 K17496 TIM50; mitochondrial import inner membrane translocase subunit TIM50
C Mitochondrial calcium uniporter complex
C Other inner membrane factors
D YDL107W MSS2; Mss2p K17798 MSS2; mitochondrial protein MSS2
D YOR266W PNT1; Pnt1p K17799 PNT1; pentamidine resistance factor, mitochondrial
D YOL027C MDM38; ribosome-binding protein MDM38 K17800 LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial
D YBR185C MBA1; Mba1p K17801 MBA1; mitochondrial protein MBA1
D YMR150C IMP1; endopeptidase catalytic subunit IMP1 K09647 IMP1; mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-]
D YMR035W IMP2; endopeptidase catalytic subunit K09648 IMP2; mitochondrial inner membrane protease subunit 2 [EC:3.4.21.-]
D YEL059C-A SOM1; Som1p K17802 SOM1; mitochondrial inner membrane protease subunit SOM1
D YDR316W OMS1; putative RNA methyltransferase K17803 OMS1; methyltransferase OMS1, mitochondrial [EC:2.1.1.-]
D YGL080W MPC1; pyruvate transporter MPC1 K22138 MPC1; mitochondrial pyruvate carrier 1
D YGR243W MPC3; mitochondrial pyruvate carrier K22139 MPC2; mitochondrial pyruvate carrier 2
D YHR162W MPC2; mitochondrial pyruvate carrier K22139 MPC2; mitochondrial pyruvate carrier 2
B Matrix
C MMC/PAM proteins
D YIL022W TIM44; protein translocase subunit TIM44 K17804 TIM44; mitochondrial import inner membrane translocase subunit TIM44
D YJR045C SSC1; Hsp70 family ATPase SSC1 K04043 dnaK; molecular chaperone DnaK
D YLR369W SSQ1; Hsp70 family ATPase SSQ1 K04043 dnaK; molecular chaperone DnaK
D YEL030W ECM10; Hsp70 family ATPase ECM10 K04043 dnaK; molecular chaperone DnaK
D YOR232W MGE1; Mge1p K03687 GRPE; molecular chaperone GrpE
D YLR008C PAM18; Pam18p K09539 DNAJC19; DnaJ homolog subfamily C member 19
D YNL328C MDJ2; Mdj2p K09539 DNAJC19; DnaJ homolog subfamily C member 19
D YJL104W PAM16; import motor complex subunit PAM16 K17805 PAM16; mitochondrial import inner membrane translocase subunit TIM16
D YKR065C PAM17; Pam17p K17806 PAM17; mitochondrial import inner membrane translocase subunit TIM23
C Other matrix factors
D YHR024C MAS2; mitochondrial-processing protease subunit alpha K01412 PMPCA; mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]
D YLR163C MAS1; mitochondrial processing peptidase K17732 PMPCB; mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]
D YKL134C OCT1; metalloendopeptidase K01410 MIPEP; mitochondrial intermediate peptidase [EC:3.4.24.59]
D YLR259C HSP60; chaperone ATPase HSP60 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D YBR044C TCM62; Tcm62p K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D YOR020C HSP10; Hsp10p K04078 groES; chaperonin GroES
D YFL016C MDJ1; Mdj1p K03686 dnaJ; molecular chaperone DnaJ
D YGR046W TAM41; putative phosphatidate cytidylyltransferase K17807 TAM41; mitochondrial translocator assembly and maintenance protein 41
D YNL310C ZIM17; Zim17p K17808 ZIM17; mitochondrial protein import protein ZIM17
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AMitochondrial quality control factors
B Regulator of mitochondrial biogenesis
C Ubiquitas transcription factors
D YJL102W MEF2; Mef2p K02355 fusA; elongation factor G
D YLR069C MEF1; Mef1p K02355 fusA; elongation factor G
C Nuclear respiratory factors
C Coactivators
C Proteins involved in Fe-S cluster biogenesis
D YCL017C NFS1; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D YPL135W ISU1; iron-binding protein ISU1 K22068 ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial
D YOR226C ISU2; putative iron-binding protein ISU2 K22068 ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial
D YER048W-A ISD11; Isd11p K22069 LYRM4; LYR motif-containing protein 4
D YDL120W YFH1; ferroxidase K19054 FXN; frataxin [EC:1.16.3.1]
D YPL252C YAH1; adrenodoxin K22071 FDX2; ferredoxin-2, mitochondrial
D YDR376W ARH1; NADPH-adrenodoxin reductase K18914 FDXR; adrenodoxin-NADP+ reductase [EC:1.18.1.6]
D YJR045C SSC1; Hsp70 family ATPase SSC1 K04043 dnaK; molecular chaperone DnaK
D YLR369W SSQ1; Hsp70 family ATPase SSQ1 K04043 dnaK; molecular chaperone DnaK
D YEL030W ECM10; Hsp70 family ATPase ECM10 K04043 dnaK; molecular chaperone DnaK
D YGL018C JAC1; J-type chaperone JAC1 K04082 hscB; molecular chaperone HscB
D YOL031C SIL1; Sil1p K14001 SIL1; nucleotide exchange factor SIL1
D YPL059W GRX5; monothiol glutaredoxin GRX5 K07390 grxD; monothiol glutaredoxin
D YLL027W ISA1; Fe-binding Fe/S cluster assembly protein ISA1 K22063 ISCA1; iron-sulfur cluster assembly 1
D YPR067W ISA2; Isa2p K22072 ISCA2; iron-sulfur cluster assembly 2
D YJR122W IBA57; Iba57p K22073 IBA57; transferase CAF17, mitochondrial [EC:2.1.-.-]
D YKL040C NFU1; Nfu1p K22074 NFU1; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
D YAL044W-A BOL1; Bol1p K22066 BOLA1; BolA-like protein 1
D YAL046C BOL3; Bol3p K22075 BOLA3; BolA-like protein 3
D YOR271C FSF1; Fsf1p K23503 SFXN5; sideroflexin-5
C Other regulator of mitochondrial biogenesis
D YBL022C PIM1; ATP-dependent Lon protease PIM1 K08675 PRSS15; ATP-dependent Lon protease [EC:3.4.21.53]
D YPR155C NCA2; Nca2p K18158 NCA2; nuclear control of ATPase protein 2
B Mitochondrial respiratory chain complex assembly factors
C Complex-I assembly factors
C Complex-II assembly factors
D YDR379C-A SDH6; Sdh6p K18167 SDHAF1; succinate dehydrogenase assembly factor 1
D YOL071W SDH5; succinate dehydrogenase assembly factor SDH5 K18168 SDHAF2; succinate dehydrogenase assembly factor 2
C Complex-III assembly factors
D YDR375C BCS1; bifunctional AAA family ATPase chaperone/translocase BCS1 K08900 BCS1; mitochondrial chaperone BCS1
D YDR493W MZM1; Mzm1p K18170 LYRM7; complex III assembly factor LYRM7
D YPL215W CBP3; Cbp3p K17662 CBP3; cytochrome b pre-mRNA-processing protein 3
C Complex-IV assembly factors
D YKL137W CMC1; Cmc1p K18171 CMC1; COX assembly mitochondrial protein 1
D YBL059C-A CMC2; Cmc2p K18172 CMC2; COX assembly mitochondrial protein 2
D YIL157C COA1; Coa1p K18173 COA1; cytochrome c oxidase assembly factor 1
D YPL189C-A COA2; Coa2p K18174 COA2; cytochrome c oxidase assembly factor 2
D YJL062W-A COA3; Coa3p K18176 COA3; cytochrome c oxidase assembly factor 3, fungi type
D YLR218C COA4; Coa4p K18177 COA4; cytochrome c oxidase assembly factor 4
D YJR034W PET191; Pet191p K18178 COA5; cytochrome c oxidase assembly factor 5
D YMR244C-A COA6; Coa6p K18179 COA6; cytochrome c oxidase assembly factor 6
D YPL172C COX10; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D YPL132W COX11; Cox11p K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D YML129C COX14; Cox14p K18181 COX14; cytochrome c oxidase assembly factor 14
D YER141W COX15; Cox15p K02259 COX15; heme a synthase [EC:1.17.99.9]
D YJL003W COX16; Cox16p K18182 COX16; cytochrome c oxidase assembly protein subunit 16
D YLL009C COX17; copper metallochaperone COX17 K02260 COX17; cytochrome c oxidase assembly protein subunit 17
D YGR062C COX18; membrane insertase COX18 K17797 COX18; mitochondrial inner membrane protein COX18
D YLL018C-A COX19; Cox19p K18183 COX19; cytochrome c oxidase assembly protein subunit 19
D YDR231C COX20; Cox20p K18184 COX20; cytochrome c oxidase assembly protein subunit 20
D YHR116W COX23; Cox23p K18185 COX23; cytochrome c oxidase assembly protein subunit 23
D YBR185C MBA1; Mba1p K17801 MBA1; mitochondrial protein MBA1
D YLR203C MSS51; Mss51p K17656 MSS51; mitochondrial splicing suppressor protein 51
D YDR079W PET100; Pet100p K18187 PET100F; protein PET100, fungi type
D YER058W PET117; Pet117p K18188 PET117; protein PET117
D YER154W OXA1; membrane insertase OXA1 K03217 yidC; YidC/Oxa1 family membrane protein insertase
D YGR112W SHY1; Shy1p K14998 SURF1; surfeit locus 1 family protein
D YBR024W SCO2; putative thioredoxin peroxidase SCO2 K07152 SCO1; protein SCO1
D YBR037C SCO1; Cu-binding protein SCO1 K07152 SCO1; protein SCO1
C Complex-V assembly factors
D YNL315C ATP11; Atp11p K07555 ATPeAF1; ATP synthase mitochondrial F1 complex assembly factor 1
D YJL180C ATP12; ATP synthase complex assembly protein ATP12 K07556 ATPeAF2; ATP synthase mitochondrial F1 complex assembly factor 2
D YIL098C FMC1; Fmc1p K18191 FMC1; ATP synthase assembly factor FMC1, mitochondrial
D YLR393W ATP10; Atp10p K18192 ATP10; mitochondrial ATPase complex subunit ATP10
B Mitochondrial dynamics
C Fission and Fusion factors
D YBR179C FZO1; mitofusin K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
D YOR211C MGM1; dynamin-related GTPase MGM1 K22140 MGM1; dynamin-like GTPase MGM1, mitochondrial
D YDR470C UGO1; Ugo1p K17967 UGO1; mitochondrial fusion and transport protein UGO1
D YLR368W MDM30; SCF ubiquitin ligase complex subunit MDM30 K15070 MDM30; mitochondrial distribution and morphology protein 30
D YKL053C-A MDM35; Mdm35p K17968 TRIAP1; TRIAP1/MDM35 family protein
D YGR101W PCP1; rhomboid protease PCP1 K09650 PARL; rhomboid-like protein [EC:3.4.21.105]
D YLL001W DNM1; dynamin-related GTPase DNM1 K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D YIL065C FIS1; Fis1p K17969 FIS1; mitochondrial fission 1 protein
D YJL112W MDV1; Mdv1p K17970 MDV1; mitochondrial division protein 1
D YKR036C CAF4; Caf4p K17970 MDV1; mitochondrial division protein 1
C Actin cytoskeleton organization
D YNL271C BNI1; formin BNI1 K11238 BNI1; cytokinesis protein
D YIL159W BNR1; formin BNR1 K17971 BNR1; BNI1-related protein 1
D YIL138C TPM2; tropomyosin TPM2 K17945 TPM1_2; tropomyosin, fungi type
D YNL079C TPM1; tropomyosin TPM1 K17945 TPM1_2; tropomyosin, fungi type
D YPR131C NAT3; peptide alpha-N-acetyltransferase complex B subunit NAT3 K17972 NAA20; N-terminal acetyltransferase B complex catalytic subunit [EC:2.3.1.254]
D YOL076W MDM20; Mdm20p K17973 NAA25; N-terminal acetyltransferase B complex non-catalytic subunit
C Mitochondrial movement
D YLL006W MMM1; ERMES complex subunit MMM1 K17764 MMM1; maintenance of mitochondrial morphology protein 1
D YAL010C MDM10; Mdm10p K17774 MDM10; mitochondrial distribution and morphology protein 10
D YGL219C MDM34; ERMES complex subunit MDM34 K17775 MDM34; mitochondrial distribution and morphology protein 34
D YJR091C JSN1; Jsn1p K17974 JSN1; protein JSN1
D YLL013C PUF3; mRNA-binding protein PUF3 K17944 PUF3; mRNA-binding protein PUF3
D YGR132C PHB1; prohibitin subunit PHB1 K17080 PHB1; prohibitin 1
D YGR231C PHB2; prohibitin subunit PHB2 K17081 PHB2; prohibitin 2
C Retention of mitochondria
D YLR190W MMR1; Mmr1p K17976 MMR1; mitochondrial MYO2 receptor-related protein 1
D YLL001W DNM1; dynamin-related GTPase DNM1 K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D YNL304W YPT11; Rab family GTPase YPT11 K17977 YPT11; GTP-binding protein YPT11
D YOR326W MYO2; myosin 2 K10357 MYO5; myosin V
D YAL029C MYO4; myosin 4 K10357 MYO5; myosin V
D YDR150W NUM1; Num1p K17978 NUM1; nuclear migration protein NUM1
C Morphogenesis factors
D YML104C MDM1; Mdm1p K17887 SNX25; sorting nexin-25
D YHR194W MDM31; Mdm31p K17979 MDM31; mitochondrial distribution and morphology protein 31
D YOR147W MDM32; Mdm32p K17980 MDM32; mitochondrial distribution and morphology protein 32
D YAL048C GEM1; ERMES complex Ca(2+)-binding regulatory GTPase GEM1 K07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
D YKR016W MIC60; Mic60p K17785 IMMT; MICOS complex subunit MIC60
D YGL129C RSM23; mitochondrial 37S ribosomal protein RSM23 K17408 DAP3; small subunit ribosomal protein S29
D YER125W RSP5; NEDD4 family E3 ubiquitin-protein ligase K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
D YMR211W DML1; Dml1p K27320 MSTO1; protein misato
D YDR393W SHE9; She9p K17983 SHE9; sensitive to high expression protein 9, mitochondrial
B Mitophagy factors
C Autophagy-related proteins
D YNL242W ATG2; Atg2p K17906 ATG2; autophagy-related protein 2
D YNR007C ATG3; Atg3p K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
D YNL223W ATG4; cysteine protease ATG4 K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D YPL149W ATG5; Atg5p K08339 ATG5; autophagy-related protein 5
D YPL120W VPS30; beclin 1 K08334 BECN; beclin
D YHR171W ATG7; Atg7p K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D YBL078C ATG8; ubiquitin-like protein ATG8 K08341 GABARAP; GABA(A) receptor-associated protein
D YDL149W ATG9; autophagy protein ATG9 K17907 ATG9; autophagy-related protein 9
D YLL042C ATG10; E2-like conjugating enzyme K08338 ATG10; ubiquitin-like-conjugating enzyme ATG10
D YPR049C ATG11; autophagy protein ATG11 K08330 ATG11; autophagy-related protein 11
D YBR217W ATG12; Atg12p K08336 ATG12; ubiquitin-like protein ATG12
D YBR128C ATG14; Atg14p K08335 ATG14; autophagy-related protein 14
D YCR068W ATG15; triglyceride lipase ATG15 K17900 ATG15; lipase ATG15 [EC:3.1.1.3]
D YMR159C ATG16; Atg16p K08340 ATG16; autophagy-related protein 16
D YLR423C ATG17; protein kinase regulatory subunit ATG17 K08329 ATG17; autophagy-related protein 17
D YFR021W ATG18; phosphoinositide binding protein ATG18 K17908 WIPI1_2; autophagy-related protein 18
D YPL100W ATG21; Atg21p K17908 WIPI1_2; autophagy-related protein 18
D YIL146C ATG32; mitophagy protein ATG32 K17984 ATG32; autophagy-related protein 32
D YEL013W VAC8; protein anchor VAC8 K08332 VAC8; vacuolar protein 8
C Parkin-dependent mechanism factors
D YGR101W PCP1; rhomboid protease PCP1 K09650 PARL; rhomboid-like protein [EC:3.4.21.105]
C Parkin-independent mechanism factors
D YPR185W ATG13; serine/threonine protein kinase regulatory subunit ATG13 K08331 ATG13; autophagy-related protein 13
D YGL180W ATG1; serine/threonine protein kinase ATG1 K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
D YPL240C HSP82; Hsp90 family chaperone HSP82 K04079 HSP90A; molecular chaperone HtpG
D YMR186W HSC82; Hsp90 family chaperone HSC82 K04079 HSP90A; molecular chaperone HtpG
D YDR168W CDC37; Cdc37p K09554 CDC37; cell division cycle protein 37
C Other mitophagy factors
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 14, 2024