+D GENES KO #

  KEGG Orthology (KO) - Sphingobium chlorophenolicum

% ! A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:sch00010] D Sphch_1090 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Sphch_0768 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Sphch_0119 Fructose-1,6-bisphosphatase class 1 K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D Sphch_2881 fructose-1,6-bisphosphatase, class II K11532 glpX-SEBP; fructose-1,6-bisphosphatase II / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37] D Sphch_1193 fructose-bisphosphate aldolase class-I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D Sphch_1261 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Sphch_1195 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Sphch_1194 Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Sphch_1133 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D Sphch_2560 Phosphoglycerate mutase K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D Sphch_0551 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Sphch_2867 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Sphch_0830 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] D Sphch_0901 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Sphch_3447 Pyruvate dehydrogenase (acetyl-transferring) K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D Sphch_0553 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Sphch_3731 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Sphch_0554 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Sphch_3732 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Sphch_1066 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Sphch_3660 Dihydrolipoyllysine-residue acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Sphch_3446 Dihydrolipoyllysine-residue acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Sphch_1350 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_1064 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3288 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3840 Alcohol dehydrogenase GroES domain protein K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D Sphch_3486 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D Sphch_0890 zinc-binding alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D Sphch_4197 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D Sphch_0462 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_0986 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3619 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3249 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_4198 Aldehyde Dehydrogenase K00138 aldB; aldehyde dehydrogenase [EC:1.2.1.-] D Sphch_2018 Acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Sphch_3727 Acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Sphch_1622 Phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] C 00020 Citrate cycle (TCA cycle) [PATH:sch00020] D Sphch_1748 citrate synthase I K01647 CS; citrate synthase [EC:2.3.3.1] D Sphch_1144 aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3] D Sphch_1342 isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D Sphch_1352 2-oxoglutarate dehydrogenase, E1 subunit K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] D Sphch_1351 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D Sphch_1350 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_1064 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3288 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_1353 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Sphch_0128 Succinyl-CoA ligase (ADP-forming) subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Sphch_1868 succinate CoA transferase K18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18] D Sphch_1696 succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D Sphch_1357 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D Sphch_1698 succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit D Sphch_1697 succinate dehydrogenase, hydrophobic membrane anchor protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit D Sphch_3177 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit K01676 E4.2.1.2A; fumarate hydratase, class I [EC:4.2.1.2] D Sphch_0310 Fumarate hydratase class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D Sphch_1354 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Sphch_1622 Phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] D Sphch_3447 Pyruvate dehydrogenase (acetyl-transferring) K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D Sphch_0553 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Sphch_3731 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Sphch_0554 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Sphch_3732 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Sphch_1066 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Sphch_3660 Dihydrolipoyllysine-residue acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Sphch_3446 Dihydrolipoyllysine-residue acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] C 00030 Pentose phosphate pathway [PATH:sch00030] D Sphch_0768 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Sphch_1088 glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D Sphch_1083 6-phosphogluconolactonase K01057 PGLS; 6-phosphogluconolactonase [EC:3.1.1.31] D Sphch_2273 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D Sphch_1196 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D Sphch_0076 transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D Sphch_0627 sugar-phosphate isomerase, RpiB/LacA/LacB family K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] D Sphch_2333 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Sphch_4175 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Sphch_1089 6-phosphogluconate dehydratase K01690 edd; phosphogluconate dehydratase [EC:4.2.1.12] D Sphch_1091 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] D Sphch_3312 membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family K00117 gcd; quinoprotein glucose dehydrogenase [EC:1.1.5.2] D Sphch_3270 membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family K00117 gcd; quinoprotein glucose dehydrogenase [EC:1.1.5.2] D Sphch_4060 Strictosidine synthase, conserved region K01053 gnl; gluconolactonase [EC:3.1.1.17] D Sphch_3563 SMP-30/Gluconolaconase/LRE-like region-containing protein K01053 gnl; gluconolactonase [EC:3.1.1.17] D Sphch_0599 SMP-30/Gluconolaconase/LRE-like region-containing protein K01053 gnl; gluconolactonase [EC:3.1.1.17] D Sphch_3087 PfkB domain protein K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45] D Sphch_1193 fructose-bisphosphate aldolase class-I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D Sphch_0119 Fructose-1,6-bisphosphatase class 1 K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D Sphch_2881 fructose-1,6-bisphosphatase, class II K11532 glpX-SEBP; fructose-1,6-bisphosphatase II / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37] C 00040 Pentose and glucuronate interconversions [PATH:sch00040] D Sphch_3100 Pectinesterase K01051 E3.1.1.11; pectinesterase [EC:3.1.1.11] D Sphch_2198 putative pectate lyase K01728 pel; pectate lyase [EC:4.2.2.2] D Sphch_3085 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase K01815 kduI; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [EC:5.3.1.17] D Sphch_3086 2-deoxy-D-gluconate 3-dehydrogenase K00065 kduD; 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase [EC:1.1.1.127] D Sphch_3091 Uronate isomerase K01812 uxaC; glucuronate isomerase [EC:5.3.1.12] D Sphch_3083 Altronate dehydratase K01685 uxaA; altronate hydrolase [EC:4.2.1.7] D Sphch_3092 Fructuronate reductase K00040 uxuB; fructuronate reductase [EC:1.1.1.57] D Sphch_0389 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Sphch_0982 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Sphch_0493 UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Sphch_2058 UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Sphch_2273 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] C 00051 Fructose and mannose metabolism [PATH:sch00051] D Sphch_2586 Fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D Sphch_1682 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D Sphch_2218 Phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8] D Sphch_0119 Fructose-1,6-bisphosphatase class 1 K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D Sphch_2881 fructose-1,6-bisphosphatase, class II K11532 glpX-SEBP; fructose-1,6-bisphosphatase II / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37] D Sphch_1193 fructose-bisphosphate aldolase class-I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D Sphch_1261 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Sphch_0627 sugar-phosphate isomerase, RpiB/LacA/LacB family K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] D Sphch_1627 PTS system fructose subfamily IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D Sphch_3496 HAD-superfamily hydrolase, subfamily IA, variant 3 K19270 hxpA; mannitol-1-/sugar-/sorbitol-6-phosphatase [EC:3.1.3.22 3.1.3.23 3.1.3.50] C 00052 Galactose metabolism [PATH:sch00052] D Sphch_1082 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Sphch_2176 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Sphch_0493 UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Sphch_2058 UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Sphch_1090 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Sphch_3431 UDP-galactopyranose mutase K01854 glf; UDP-galactopyranose mutase [EC:5.4.99.9] D Sphch_0107 alpha amylase catalytic region K01187 malZ; alpha-glucosidase [EC:3.2.1.20] C 00053 Ascorbate and aldarate metabolism [PATH:sch00053] D Sphch_0389 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Sphch_0982 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Sphch_4060 Strictosidine synthase, conserved region K01053 gnl; gluconolactonase [EC:3.1.1.17] D Sphch_3563 SMP-30/Gluconolaconase/LRE-like region-containing protein K01053 gnl; gluconolactonase [EC:3.1.1.17] D Sphch_0599 SMP-30/Gluconolaconase/LRE-like region-containing protein K01053 gnl; gluconolactonase [EC:3.1.1.17] D Sphch_2557 UDP-glucuronate 4-epimerase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] D Sphch_0462 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_0986 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3619 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3249 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_4072 2-dehydro-3-deoxyglucarate aldolase K01630 garL; 2-dehydro-3-deoxyglucarate aldolase [EC:4.1.2.20] D Sphch_3093 5-dehydro-4-deoxyglucarate dehydratase K01707 kdgD; 5-dehydro-4-deoxyglucarate dehydratase [EC:4.2.1.41] C 00500 Starch and sucrose metabolism [PATH:sch00500] D Sphch_0107 alpha amylase catalytic region K01187 malZ; alpha-glucosidase [EC:3.2.1.20] D Sphch_2587 Levansucrase K00692 sacB; levansucrase [EC:2.4.1.10] D Sphch_0493 UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Sphch_2058 UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Sphch_1290 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_1564 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_1862 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_2775 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_1289 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_0586 Glucose-1-phosphate adenylyltransferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] D Sphch_0587 Glycogen synthase K00703 glgA; starch synthase [EC:2.4.1.21] D Sphch_2897 glycosyl transferase group 1 K16150 K16150; glycogen synthase [EC:2.4.1.11] D Sphch_0585 1,4-alpha-glucan-branching enzyme K00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18] D Sphch_0584 glycogen/starch/alpha-glucan phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1] D Sphch_0588 glycogen debranching enzyme GlgX K02438 glgX; glycogen debranching enzyme [EC:3.2.1.196] D Sphch_0398 alpha,alpha-trehalose-phosphate synthase (UDP-forming) K00697 otsA; trehalose 6-phosphate synthase [EC:2.4.1.15 2.4.1.347] D Sphch_0400 trehalose-phosphatase K01087 otsB; trehalose 6-phosphate phosphatase [EC:3.1.3.12] D Sphch_1090 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Sphch_0768 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Sphch_2586 Fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:sch00520] D Sphch_1443 Beta-N-acetylhexosaminidase K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] D Sphch_2586 Fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D Sphch_1344 Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Sphch_1469 phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10] D Sphch_1346 Bifunctional protein glmU K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D Sphch_0527 Anhydro-N-acetylmuramic acid kinase K09001 anmK; anhydro-N-acetylmuramic acid kinase [EC:2.7.1.170] D Sphch_0730 aminoglycoside phosphotransferase K07102 amgK; N-acetylmuramate 1-kinase [EC:2.7.1.221] D Sphch_0729 Nucleotidyl transferase K00992 murU; N-acetyl-alpha-D-muramate 1-phosphate uridylyltransferase [EC:2.7.7.99] D Sphch_1572 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D Sphch_1420 UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D Sphch_0390 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D Sphch_0391 nucleotide sugar dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336] D Sphch_3101 glycoside hydrolase family 43 K01198 xynB; xylan 1,4-beta-xylosidase [EC:3.2.1.37] D Sphch_1090 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Sphch_0493 UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Sphch_2058 UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Sphch_0389 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Sphch_0982 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Sphch_1082 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Sphch_2176 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Sphch_3431 UDP-galactopyranose mutase K01854 glf; UDP-galactopyranose mutase [EC:5.4.99.9] D Sphch_2557 UDP-glucuronate 4-epimerase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] D Sphch_1627 PTS system fructose subfamily IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D Sphch_0768 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Sphch_2218 Phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8] D Sphch_1682 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D Sphch_0586 Glucose-1-phosphate adenylyltransferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] C 00620 Pyruvate metabolism [PATH:sch00620] D Sphch_2018 Acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Sphch_3727 Acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Sphch_3447 Pyruvate dehydrogenase (acetyl-transferring) K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D Sphch_0553 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Sphch_3731 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Sphch_0554 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Sphch_3732 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Sphch_1066 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Sphch_3660 Dihydrolipoyllysine-residue acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Sphch_3446 Dihydrolipoyllysine-residue acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Sphch_1350 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_1064 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3288 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3494 Acetaldehyde dehydrogenase K04073 mhpF; acetaldehyde dehydrogenase [EC:1.2.1.10] D Sphch_0890 zinc-binding alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D Sphch_4197 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D Sphch_3840 Alcohol dehydrogenase GroES domain protein K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D Sphch_3486 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D Sphch_2867 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Sphch_1321 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D Sphch_1678 acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D Sphch_1679 acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D Sphch_0665 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D Sphch_0695 Acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D Sphch_0462 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_0986 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3619 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3249 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_4198 Aldehyde Dehydrogenase K00138 aldB; aldehyde dehydrogenase [EC:1.2.1.-] D Sphch_1868 succinate CoA transferase K18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18] D Sphch_1846 (S)-2-hydroxy-acid oxidase K00101 lldD; L-lactate dehydrogenase (cytochrome) [EC:1.1.2.3] D Sphch_3257 lactoylglutathione lyase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5] D Sphch_2061 Glyoxalase/bleomycin resistance protein/dioxygenase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5] D Sphch_2062 Hydroxyacylglutathione hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D Sphch_2307 beta-lactamase-like protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D Sphch_0642 malic protein NAD-binding protein K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] D Sphch_2205 malic protein NAD-binding protein K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] D Sphch_1354 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Sphch_3177 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit K01676 E4.2.1.2A; fumarate hydratase, class I [EC:4.2.1.2] D Sphch_0310 Fumarate hydratase class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D Sphch_2430 Phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D Sphch_1622 Phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] D Sphch_0830 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] D Sphch_0901 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Sphch_0644 malate synthase G K01638 aceB; malate synthase [EC:2.3.3.9] D Sphch_0612 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0180 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0094 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0995 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3248 acetyl-coenzyme A synthetase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_1080 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3982 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0756 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3830 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3834 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3054 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3883 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3885 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3931 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3997 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3506 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3670 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3497 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3386 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0563 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:sch00630] D Sphch_2843 Isocitrate lyase K01637 E4.1.3.1; isocitrate lyase [EC:4.1.3.1] D Sphch_2018 Acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Sphch_3727 Acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Sphch_0644 malate synthase G K01638 aceB; malate synthase [EC:2.3.3.9] D Sphch_1354 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Sphch_1748 citrate synthase I K01647 CS; citrate synthase [EC:2.3.3.1] D Sphch_1144 aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3] D Sphch_0612 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0180 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0094 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0995 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3248 acetyl-coenzyme A synthetase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_1080 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3982 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0756 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3830 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3834 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3054 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3883 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3885 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3931 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3997 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3506 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3670 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3497 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3386 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3122 acetoacetyl-CoA reductase K00023 phbB; acetoacetyl-CoA reductase [EC:1.1.1.36] D Sphch_0763 methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] D Sphch_3630 hypothetical protein K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] D Sphch_1000 Butyryl-CoA dehydrogenase K14448 mcd; (2S)-methylsuccinyl-CoA dehydrogenase [EC:1.3.8.12] D Sphch_1616 HpcH/HpaI aldolase K14451 mcl2; (3S)-malyl-CoA thioesterase [EC:3.1.2.30] D Sphch_0760 Propionyl-CoA carboxylase K01965 PCCA; propionyl-CoA carboxylase alpha chain [EC:6.4.1.3] D Sphch_0764 Propionyl-CoA carboxylase K01966 PCCB; propionyl-CoA carboxylase beta chain [EC:6.4.1.3 2.1.3.15] D Sphch_0762 methylmalonyl-CoA mutase, large subunit K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] D Sphch_3012 Catalase K03781 katE; catalase [EC:1.11.1.6] D Sphch_1150 Glyoxylate reductase K00015 gyaR; glyoxylate reductase [EC:1.1.1.26] D Sphch_0295 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18] D Sphch_1347 phosphoglycolate phosphatase K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18] D Sphch_1004 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Sphch_0626 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Sphch_1411 glycine dehydrogenase (decarboxylating) subunit 1 K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2] D Sphch_1410 aminotransferase class V K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2] D Sphch_1413 glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D Sphch_1350 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_1064 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3288 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_1412 Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein D Sphch_0683 Hydroxypyruvate isomerase K01816 hyi; hydroxypyruvate isomerase [EC:5.3.1.22] D Sphch_2834 putative kinase K15918 GLYK; D-glycerate 3-kinase [EC:2.7.1.31] D Sphch_1091 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] D Sphch_3722 NAD-dependent formate dehydrogenase delta subunit K00126 fdsD; formate dehydrogenase subunit delta [EC:1.17.1.9] D Sphch_3721 formate dehydrogenase, alpha subunit K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9] D Sphch_3720 NADH dehydrogenase (quinone) K00124 fdoH; formate dehydrogenase iron-sulfur subunit D Sphch_3719 NADH dehydrogenase (ubiquinone) 24 kDa subunit K00127 fdoI; formate dehydrogenase subunit gamma D Sphch_0428 formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10] D Sphch_4021 formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10] C 00640 Propanoate metabolism [PATH:sch00640] D Sphch_2018 Acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Sphch_3727 Acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Sphch_3302 Propionate--CoA ligase K01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17] D Sphch_1205 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4] D Sphch_3285 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4] D Sphch_1204 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4] D Sphch_3286 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4] D Sphch_3973 Pyruvate dehydrogenase (acetyl-transferring) K11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] D Sphch_3452 Pyruvate dehydrogenase (acetyl-transferring) K11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] D Sphch_1203 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] D Sphch_3287 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] D Sphch_1350 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_1064 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3288 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_1075 Enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D Sphch_0181 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_1081 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_1321 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D Sphch_1678 acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D Sphch_1679 acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D Sphch_0665 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D Sphch_0449 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48] D Sphch_0760 Propionyl-CoA carboxylase K01965 PCCA; propionyl-CoA carboxylase alpha chain [EC:6.4.1.3] D Sphch_0764 Propionyl-CoA carboxylase K01966 PCCB; propionyl-CoA carboxylase beta chain [EC:6.4.1.3 2.1.3.15] D Sphch_0763 methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] D Sphch_3630 hypothetical protein K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] D Sphch_0762 methylmalonyl-CoA mutase, large subunit K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] D Sphch_0128 Succinyl-CoA ligase (ADP-forming) subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Sphch_1353 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Sphch_3374 methylmalonate-semialdehyde dehydrogenase K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] C 00650 Butanoate metabolism [PATH:sch00650] D Sphch_0612 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0180 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0094 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0995 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3248 acetyl-coenzyme A synthetase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_1080 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3982 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0756 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3830 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3834 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3054 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3883 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3885 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3931 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3997 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3506 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3670 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3497 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3386 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_2045 3-hydroxybutyryl-CoA dehydrogenase K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] D Sphch_0602 3-hydroxybutyryl-CoA epimerase K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] D Sphch_0101 3-hydroxybutyryl-CoA epimerase K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] D Sphch_2113 3-hydroxybutyryl-CoA epimerase K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] D Sphch_3642 3-hydroxybutyryl-CoA epimerase K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] D Sphch_3390 3-hydroxybutyryl-CoA epimerase K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] D Sphch_0181 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_1081 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_1075 Enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D Sphch_3494 Acetaldehyde dehydrogenase K04073 mhpF; acetaldehyde dehydrogenase [EC:1.2.1.10] D Sphch_1979 poly(R)-hydroxyalkanoic acid synthase, class I K03821 phaC; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304] D Sphch_0755 polyhydroxyalkanoate synthase K03821 phaC; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304] D Sphch_0491 polyhydroxyalkanoate depolymerase, intracellular K05973 phaZ; poly(3-hydroxybutyrate) depolymerase [EC:3.1.1.75] D Sphch_3122 acetoacetyl-CoA reductase K00023 phbB; acetoacetyl-CoA reductase [EC:1.1.1.36] D Sphch_1696 succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D Sphch_1357 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D Sphch_1698 succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit D Sphch_1697 succinate dehydrogenase, hydrophobic membrane anchor protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit D Sphch_0449 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48] D Sphch_0450 Succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3080 Betaine-aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3972 succinic semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_4065 succinic semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3471 Succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_1868 succinate CoA transferase K18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18] D Sphch_3831 protein of unknown function DUF35 K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D Sphch_3872 Hydroxymethylglutaryl-CoA lyase K01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4] D Sphch_1033 3-oxoacid CoA-transferase, A subunit K01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5] D Sphch_3523 3-oxoacid CoA-transferase, A subunit K01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5] D Sphch_1034 3-oxoacid CoA-transferase, B subunit K01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5] D Sphch_3522 3-oxoacid CoA-transferase, B subunit K01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5] D Sphch_3998 acetoacetyl-CoA synthase K01907 AACS; acetoacetyl-CoA synthetase [EC:6.2.1.16] D Sphch_1529 3-hydroxybutyrate dehydrogenase K00019 BDH1; 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30] D Sphch_2928 3-hydroxybutyrate dehydrogenase K00019 BDH1; 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30] D Sphch_0888 L-iditol 2-dehydrogenase K18369 adh2; alcohol dehydrogenase [EC:1.1.1.-] D Sphch_0568 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Sphch_4067 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Sphch_3354 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Sphch_0566 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Sphch_0158 3-oxoacyl-(acyl-carrier-protein) reductase K18009 budC; meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304] C 00660 C5-Branched dibasic acid metabolism [PATH:sch00660] D Sphch_0568 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Sphch_4067 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Sphch_3354 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Sphch_0566 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Sphch_0128 Succinyl-CoA ligase (ADP-forming) subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Sphch_1353 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Sphch_3893 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase K10218 ligK; 4-hydroxy-4-methyl-2-oxoglutarate aldolase [EC:4.1.3.17] D Sphch_2845 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Sphch_3291 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Sphch_3871 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Sphch_2847 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Sphch_3290 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Sphch_3870 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Sphch_0371 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D Sphch_3306 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] C 00562 Inositol phosphate metabolism [PATH:sch00562] D Sphch_1187 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Sphch_2081 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Sphch_3374 methylmalonate-semialdehyde dehydrogenase K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] D Sphch_1261 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:sch00190] D Sphch_1186 NAD(P)H-quinone oxidoreductase subunit 3 K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2] D Sphch_1185 NAD(P)H-quinone oxidoreductase subunit K K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2] D Sphch_1184 NAD(P)H-quinone oxidoreductase subunit J K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2] D Sphch_1183 NAD(P)H-quinone oxidoreductase subunit H K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2] D Sphch_1182 NADH-quinone oxidoreductase, E subunit K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2] D Sphch_1181 NADH-quinone oxidoreductase, F subunit K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2] D Sphch_1180 NADH-quinone oxidoreductase, chain G K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2] D Sphch_1179 NAD(P)H-quinone oxidoreductase subunit 1 K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2] D Sphch_1178 NAD(P)H-quinone oxidoreductase subunit I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2] D Sphch_1177 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2] D Sphch_1176 NAD(P)H-quinone oxidoreductase subunit 4L K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2] D Sphch_1175 proton-translocating NADH-quinone oxidoreductase, chain L K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2] D Sphch_1174 proton-translocating NADH-quinone oxidoreductase, chain M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2] D Sphch_1173 NAD(P)H-quinone oxidoreductase subunit 2 K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2] D Sphch_1696 succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D Sphch_1357 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D Sphch_1698 succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit D Sphch_1697 succinate dehydrogenase, hydrophobic membrane anchor protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit D Sphch_2675 ubiquinol-cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8] D Sphch_2676 Cytochrome b/b6 domain protein K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit D Sphch_2677 cytochrome c1 K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit D Sphch_2457 Protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D Sphch_1103 cytochrome o ubiquinol oxidase subunit IV K02300 cyoD; cytochrome o ubiquinol oxidase subunit IV D Sphch_0110 hypothetical protein K02277 coxD; cytochrome c oxidase subunit IV [EC:7.1.1.9] D Sphch_0111 cytochrome c oxidase subunit III K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9] D Sphch_0112 cytochrome c oxidase subunit III K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9] D Sphch_2460 cytochrome c oxidase subunit III K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9] D Sphch_3423 cytochrome c oxidase subunit III K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9] D Sphch_0113 cytochrome c oxidase subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9] D Sphch_2456 cytochrome c oxidase, subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9] D Sphch_3422 cytochrome c oxidase subunit I K15408 coxAC; cytochrome c oxidase subunit I+III [EC:7.1.1.9] D Sphch_0114 cytochrome c oxidase subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9] D Sphch_2455 cytochrome c oxidase, subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9] D Sphch_2459 Cytochrome c oxidase assembly protein ctaG K02258 COX11; cytochrome c oxidase assembly protein subunit 11 D Sphch_0080 Heme A synthase K02259 COX15; heme a synthase [EC:1.17.99.9] D Sphch_3401 cytochrome c oxidase, cbb3-type, subunit I K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9] D Sphch_3402 cytochrome c oxidase, cbb3-type, subunit II K00405 ccoO; cytochrome c oxidase cbb3-type subunit II D Sphch_3403 Cbb3-type cytochrome oxidase subunit 3 K00407 ccoQ; cytochrome c oxidase cbb3-type subunit IV D Sphch_3404 cytochrome c oxidase, cbb3-type, subunit III K00406 ccoP; cytochrome c oxidase cbb3-type subunit III D Sphch_1102 cytochrome o ubiquinol oxidase, subunit III K02299 cyoC; cytochrome o ubiquinol oxidase subunit III D Sphch_1101 cytochrome o ubiquinol oxidase, subunit I K02298 cyoB; cytochrome o ubiquinol oxidase subunit I [EC:7.1.1.3] D Sphch_1100 ubiquinol oxidase, subunit II K02297 cyoA; cytochrome o ubiquinol oxidase subunit II [EC:7.1.1.3] D Sphch_0109 cytochrome c class I K08738 CYC; cytochrome c D Sphch_0996 cytochrome c class I K08738 CYC; cytochrome c D Sphch_2835 cytochrome c class I K08738 CYC; cytochrome c D Sphch_0069 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D Sphch_0066 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D Sphch_0067 ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D Sphch_0070 ATP synthase subunit delta K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D Sphch_0065 ATPase, F1 complex, delta/epsilon subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D Sphch_0346 ATP synthase subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a D Sphch_0348 H+transporting two-sector ATPase B/B' subunit K02109 ATPF0B; F-type H+-transporting ATPase subunit b D Sphch_0349 ATP synthase subunit b K02109 ATPF0B; F-type H+-transporting ATPase subunit b D Sphch_0347 H+transporting two-sector ATPase C subunit K02110 ATPF0C; F-type H+-transporting ATPase subunit c D Sphch_2282 Inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1] D Sphch_2822 Polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation in photosynthetic organisms C 00720 Carbon fixation pathways in prokaryotes C 00680 Methane metabolism [PATH:sch00680] D Sphch_3840 Alcohol dehydrogenase GroES domain protein K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D Sphch_3486 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D Sphch_3485 S-formylglutathione hydrolase K01070 frmB; S-formylglutathione hydrolase [EC:3.1.2.12] D Sphch_3721 formate dehydrogenase, alpha subunit K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9] D Sphch_3720 NADH dehydrogenase (quinone) K00124 fdoH; formate dehydrogenase iron-sulfur subunit D Sphch_3719 NADH dehydrogenase (ubiquinone) 24 kDa subunit K00127 fdoI; formate dehydrogenase subunit gamma D Sphch_3722 NAD-dependent formate dehydrogenase delta subunit K00126 fdsD; formate dehydrogenase subunit delta [EC:1.17.1.9] D Sphch_0626 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Sphch_0551 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Sphch_2430 Phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D Sphch_1354 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Sphch_1193 fructose-bisphosphate aldolase class-I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D Sphch_0119 Fructose-1,6-bisphosphatase class 1 K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D Sphch_2881 fructose-1,6-bisphosphatase, class II K11532 glpX-SEBP; fructose-1,6-bisphosphatase II / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37] D Sphch_1857 Trimethylamine dehydrogenase K00317 dmd-tmd; dimethylamine/trimethylamine dehydrogenase [EC:1.5.8.1 1.5.8.2] D Sphch_1884 putative F420-dependent oxidoreductase, MSMEG_2249 family K00320 mer; 5,10-methylenetetrahydromethanopterin reductase [EC:1.5.98.2] D Sphch_2018 Acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Sphch_3727 Acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Sphch_0901 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Sphch_1133 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D Sphch_2560 Phosphoglycerate mutase K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D Sphch_1966 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Sphch_1967 phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Sphch_0570 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D Sphch_0610 FO synthase subunit 1 K11779 fbiC; FO synthase [EC:2.5.1.147 4.3.1.32] D Sphch_2129 FO synthase subunit 1 K11779 fbiC; FO synthase [EC:2.5.1.147 4.3.1.32] D Sphch_2204 2-phospho-L-lactate guanylyltransferase CofC K14941 cofC; 2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase [EC:2.7.7.68 2.7.7.105] D Sphch_2203 LPPG:FO 2-phospho-L-lactate transferase K11212 cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28] D Sphch_2140 protein of unknown function DUF129 K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34] D Sphch_2202 F420-dependent oxidoreductase K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34] C 00910 Nitrogen metabolism [PATH:sch00910] D Sphch_1721 major facilitator superfamily MFS_1 K02575 NRT2; MFS transporter, NNP family, nitrate/nitrite transporter D Sphch_0688 ABC-type nitrate/sulfonate/bicarbonate transport system periplasmic component K15576 nrtA; nitrate/nitrite transport system substrate-binding protein D Sphch_0689 nitrate ABC transporter, inner membrane subunit K15577 nrtB; nitrate/nitrite transport system permease protein D Sphch_0690 nitrate ABC transporter, ATPase subunits C and D K15578 nrtC; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4] D Sphch_1666 Nitrate reductase K00372 nasC; assimilatory nitrate reductase catalytic subunit [EC:1.7.99.-] D Sphch_1718 Nitrate reductase K00372 nasC; assimilatory nitrate reductase catalytic subunit [EC:1.7.99.-] D Sphch_1720 nitrite reductase (NAD(P)H), large subunit K26139 nasD; nitrite reductase [NAD(P)H] large subunit [EC:1.7.1.4] D Sphch_1719 nitrite reductase (NAD(P)H), small subunit K26138 nasE; nitrite reductase [NAD(P)H] small subunit [EC:1.7.1.4] D Sphch_1109 2-nitropropane dioxygenase NPD K00459 ncd2; nitronate monooxygenase [EC:1.13.12.16] D Sphch_1005 2-nitropropane dioxygenase NPD K00459 ncd2; nitronate monooxygenase [EC:1.13.12.16] D Sphch_3443 2-nitropropane dioxygenase NPD K00459 ncd2; nitronate monooxygenase [EC:1.13.12.16] D Sphch_3112 NAD-glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2] D Sphch_3518 response regulator receiver protein K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] D Sphch_1004 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Sphch_1900 Glutamate synthase (ferredoxin) K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D Sphch_1902 glutamate synthase, small subunit K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D Sphch_0697 Carbonate dehydratase K01673 cynT; carbonic anhydrase [EC:4.2.1.1] D Sphch_1388 Carbonate dehydratase K01673 cynT; carbonic anhydrase [EC:4.2.1.1] C 00920 Sulfur metabolism [PATH:sch00920] D Sphch_3736 aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein D Sphch_3548 aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein D Sphch_3539 ABC-type transporter, periplasmic subunit family 3 K15553 ssuA; sulfonate transport system substrate-binding protein D Sphch_3543 ABC-type transporter, integral membrane subunit K15554 ssuC; sulfonate transport system permease protein D Sphch_3544 Polyamine-transporting ATPase K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D Sphch_3547 Alkanesulfonate monooxygenase K04091 ssuD; alkanesulfonate monooxygenase [EC:1.14.14.5 1.14.14.34] D Sphch_3380 Sulfate adenylyltransferase subunit 1 K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25] D Sphch_3381 Sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4] D Sphch_3379 inositol monophosphatase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] D Sphch_0275 Phosphoadenylyl-sulfate reductase (thioredoxin) K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] D Sphch_3956 Sulfite oxidase K05301 sorA; sulfite dehydrogenase (cytochrome) subunit A [EC:1.8.2.1] D Sphch_0277 nitrite and sulphite reductase 4Fe-4S region K00381 cysI; sulfite reductase (NADPH) hemoprotein beta-component [EC:1.8.1.2] D Sphch_2469 3-mercaptopyruvate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Sphch_0484 serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Sphch_1383 Serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Sphch_1111 Serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Sphch_1435 Cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47] D Sphch_3515 cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47] D Sphch_0292 Homoserine O-succinyltransferase K00651 metA; homoserine O-succinyltransferase/O-acetyltransferase [EC:2.3.1.46 2.3.1.31] D Sphch_2347 Homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] D Sphch_0372 O-succinylhomoserine sulfhydrylase K10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-] D Sphch_3173 Butyryl-CoA dehydrogenase K20035 dmdC; 3-(methylsulfanyl)propanoyl-CoA dehydrogenase [EC:1.3.99.41] D Sphch_3886 acyl-CoA dehydrogenase domain-containing protein K20035 dmdC; 3-(methylsulfanyl)propanoyl-CoA dehydrogenase [EC:1.3.99.41] D Sphch_4171 Isoprenylcysteine carboxyl methyltransferase K21310 mddA; methanethiol S-methyltransferase [EC:2.1.1.334] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:sch00061] D Sphch_1321 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D Sphch_1678 acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D Sphch_1679 acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D Sphch_0665 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D Sphch_0323 acyl carrier protein K02078 acpP; acyl carrier protein D Sphch_1242 hypothetical protein K02078 acpP; acyl carrier protein D Sphch_1404 phosphopantetheine-binding protein K02078 acpP; acyl carrier protein D Sphch_0320 malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D Sphch_2311 3-oxoacyl-(acyl-carrier-protein) synthase 3 K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D Sphch_0324 3-oxoacyl-(acyl-carrier-protein) synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D Sphch_0607 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_0322 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_3974 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_3566 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_3571 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_1328 (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D Sphch_1955 Enoyl-(acyl-carrier-protein) reductase (NADH) K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D Sphch_1612 2-nitropropane dioxygenase NPD K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9] D Sphch_0456 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0228 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_2064 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_2957 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3826 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3842 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3589 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0684 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3839 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0604 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 00062 Fatty acid elongation C 00071 Fatty acid degradation [PATH:sch00071] D Sphch_0612 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0180 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0094 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0995 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3248 acetyl-coenzyme A synthetase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_1080 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3982 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0756 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3830 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3834 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3054 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3883 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3885 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3931 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3997 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3506 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3670 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3497 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3386 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_2144 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_3243 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_4038 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_0181 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_1081 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_1075 Enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D Sphch_0602 3-hydroxybutyryl-CoA epimerase K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] D Sphch_0101 3-hydroxybutyryl-CoA epimerase K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] D Sphch_2113 3-hydroxybutyryl-CoA epimerase K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] D Sphch_3642 3-hydroxybutyryl-CoA epimerase K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] D Sphch_3390 3-hydroxybutyryl-CoA epimerase K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] D Sphch_3509 Butyryl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_3822 Butyryl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_3365 (R)-benzylsuccinyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_3393 Long-chain-acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_0606 Butyryl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_0179 Long-chain-acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_2103 Butyryl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_3240 Long-chain-acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_0989 acyl-CoA dehydrogenase domain-containing protein K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_3991 Long-chain-acyl-CoA dehydrogenase K00255 ACADL; long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8] D Sphch_3225 Glutaryl-CoA dehydrogenase K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6] D Sphch_0456 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0228 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_2064 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_2957 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3826 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3842 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3589 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0684 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3839 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0604 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3944 Ferredoxin--NAD(+) reductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3] D Sphch_0328 Ferredoxin--NAD(+) reductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3] D Sphch_3840 Alcohol dehydrogenase GroES domain protein K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D Sphch_3486 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D Sphch_0890 zinc-binding alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D Sphch_4197 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D Sphch_0462 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_0986 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3619 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3249 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis [PATH:sch00100] D Sphch_2837 fatty acid hydroxylase K00227 SC5DL; Delta7-sterol 5-desaturase [EC:1.14.19.20] C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis [PATH:sch00121] D Sphch_3661 o-succinylbenzoate--CoA ligase K15868 baiB; bile acid-coenzyme A ligase [EC:6.2.1.7] C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism [PATH:sch00561] D Sphch_2834 putative kinase K15918 GLYK; D-glycerate 3-kinase [EC:2.7.1.31] D Sphch_0462 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_0986 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3619 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3249 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_2878 Glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D Sphch_2310 Phosphate acyltransferase K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D Sphch_0775 Glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D Sphch_2351 phospholipid/glycerol acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 00564 Glycerophospholipid metabolism [PATH:sch00564] D Sphch_2325 Glycerol-3-phosphate dehydrogenase (NAD(P)+) K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] D Sphch_2877 Glycerol-3-phosphate dehydrogenase K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] D Sphch_0775 Glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D Sphch_2351 phospholipid/glycerol acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D Sphch_1364 alpha/beta hydrolase fold protein K01048 pldB; lysophospholipase [EC:3.1.1.5] D Sphch_2305 glycerophosphoryl diester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] D Sphch_1070 phospholipid N-methyltransferase K00570 pmtA; phosphatidylethanolamine/phosphatidyl-N-methylethanolamine N-methyltransferase [EC:2.1.1.17 2.1.1.71] D Sphch_1333 phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41] D Sphch_1340 CDP-alcohol phosphatidyltransferase K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8] D Sphch_1341 Phosphatidylserine decarboxylase proenzyme K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65] D Sphch_2479 phospholipase D/Transphosphatidylase K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-] D Sphch_1116 CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase K08744 CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism [PATH:sch00592] D Sphch_2144 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_3243 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_4038 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] C 01040 Biosynthesis of unsaturated fatty acids [PATH:sch01040] D Sphch_3409 lipolytic protein G-D-S-L family K10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5] D Sphch_3608 Choloyl-CoA hydrolase K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-] D Sphch_1065 thioesterase superfamily protein K10806 yciA; acyl-CoA thioesterase YciA [EC:3.1.2.-] D Sphch_2289 thioesterase superfamily protein K10806 yciA; acyl-CoA thioesterase YciA [EC:3.1.2.-] B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:sch00230] D Sphch_1662 NUDIX hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D Sphch_2333 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Sphch_4175 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Sphch_0807 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D Sphch_2083 Phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D Sphch_2818 phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D Sphch_1312 Phosphoribosylglycinamide formyltransferase 2 K08289 purT; phosphoribosylglycinamide formyltransferase 2 [EC:6.3.1.21] D Sphch_1311 Phosphoribosylformylglycinamidine synthase 2 K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3] D Sphch_0395 phosphoribosylformylglycinamidine synthase, purS K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3] D Sphch_0394 Phosphoribosylformylglycinamidine synthase 1 K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Sphch_2819 phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D Sphch_1131 phosphoribosylaminoimidazole carboxylase, ATPase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] D Sphch_1132 phosphoribosylaminoimidazole carboxylase, catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D Sphch_0397 Phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D Sphch_1208 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D Sphch_2312 Bifunctional purine biosynthesis protein purH K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D Sphch_2678 Adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Sphch_0243 Multifunctional protein surE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Sphch_2293 Multi-copper polyphenol oxidoreductase, laccase K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] D Sphch_1589 inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D Sphch_1579 Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Sphch_2855 Nucleoside-triphosphatase rdgB K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D Sphch_1995 Xanthine dehydrogenase K11177 yagR; xanthine dehydrogenase YagR molybdenum-binding subunit [EC:1.17.1.4] D Sphch_1996 Xanthine dehydrogenase K11178 yagS; xanthine dehydrogenase YagS FAD-binding subunit [EC:1.17.1.4] D Sphch_1997 (2Fe-2S)-binding domain-containing protein K13483 yagT; xanthine dehydrogenase YagT iron-sulfur-binding subunit D Sphch_0489 glutamine amidotransferase class-I K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Sphch_1876 GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Sphch_0312 Guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8] D Sphch_3180 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Sphch_3182 Ribonucleoside-diphosphate reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D Sphch_1414 Deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 dgt; dGTPase [EC:3.1.5.1] D Sphch_3191 deoxyguanosinetriphosphate triphosphohydrolase K01129 dgt; dGTPase [EC:3.1.5.1] D Sphch_2797 (p)ppGpp synthetase I, SpoT/RelA K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D Sphch_2823 Ppx/GppA phosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] D Sphch_1839 Ppx/GppA phosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] D Sphch_3775 adenylate/guanylate cyclase with Chase sensor K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Sphch_1395 adenylate cyclase K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Sphch_1963 Adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D Sphch_0737 AMP nucleosidase K01241 amn; AMP nucleosidase [EC:3.2.2.4] D Sphch_1808 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Sphch_0709 MazG family protein K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9] D Sphch_3783 metallophosphoesterase K03651 cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53] D Sphch_3380 Sulfate adenylyltransferase subunit 1 K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25] D Sphch_3381 Sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4] C 00240 Pyrimidine metabolism [PATH:sch00240] D Sphch_0543 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Sphch_2177 ATP-dependent carboxylate-amine ligase domain protein ATP-grasp K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Sphch_0540 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D Sphch_2981 Aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D Sphch_0289 dihydroorotase, multifunctional complex type K01465 URA4; dihydroorotase [EC:3.5.2.3] D Sphch_2983 amidohydrolase K01465 URA4; dihydroorotase [EC:3.5.2.3] D Sphch_2034 Dihydroorotate dehydrogenase K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2] D Sphch_2454 Orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D Sphch_0256 orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D Sphch_1336 uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D Sphch_1579 Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Sphch_0709 MazG family protein K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9] D Sphch_2225 Septum formation protein Maf K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-] D Sphch_2394 Septum formation protein Maf K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-] D Sphch_1259 CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2] D Sphch_0650 Cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D Sphch_0243 Multifunctional protein surE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Sphch_0270 cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5] D Sphch_0269 Deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13] D Sphch_3180 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Sphch_3182 Ribonucleoside-diphosphate reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D Sphch_0717 Thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D Sphch_1595 Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D Sphch_4174 thymidine phosphorylase K00758 deoA; thymidine phosphorylase [EC:2.4.2.4] D Sphch_1250 Thymidine kinase K00857 tdk; thymidine kinase [EC:2.7.1.21] D Sphch_1206 Thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] D Sphch_0459 amidase, hydantoinase/carbamoylase family K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87] D Sphch_4049 NADH dehydrogenase/NAD(P)H nitroreductase rutE K09019 rutE; 3-hydroxypropanoate dehydrogenase [EC:1.1.1.-] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:sch00250] D Sphch_1556 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Sphch_2815 L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16] D Sphch_2794 aspartate racemase K01779 racD; aspartate racemase [EC:5.1.1.13] D Sphch_1373 Asparaginase/glutaminase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D Sphch_3427 Asparaginase K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5] D Sphch_1229 exosortase 1 system-associated amidotransferase 1 K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D Sphch_2715 asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D Sphch_2556 alanine dehydrogenase K00259 ald; alanine dehydrogenase [EC:1.4.1.1] D Sphch_2601 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Sphch_1733 Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Sphch_1963 Adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D Sphch_1208 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D Sphch_2981 Aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D Sphch_0449 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48] D Sphch_0450 Succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3080 Betaine-aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3972 succinic semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_4065 succinic semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3471 Succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_1900 Glutamate synthase (ferredoxin) K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D Sphch_1902 glutamate synthase, small subunit K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D Sphch_3112 NAD-glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2] D Sphch_3518 response regulator receiver protein K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] D Sphch_3483 delta-1-pyrroline-5-carboxylate dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88] D Sphch_1004 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Sphch_0543 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Sphch_2177 ATP-dependent carboxylate-amine ligase domain protein ATP-grasp K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Sphch_0540 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D Sphch_0646 Glutaminase K01425 glsA; glutaminase [EC:3.5.1.2] D Sphch_0394 Phosphoribosylformylglycinamidine synthase 1 K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Sphch_1344 Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Sphch_0807 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:sch00260] D Sphch_1613 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Sphch_0740 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Sphch_2882 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Sphch_1448 Homoserine kinase K02204 thrB2; homoserine kinase type II [EC:2.7.1.39] D Sphch_2463 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D Sphch_2021 Threonine aldolase K01620 ltaE; threonine aldolase [EC:4.1.2.48] D Sphch_0626 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Sphch_1133 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D Sphch_2560 Phosphoglycerate mutase K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D Sphch_2834 putative kinase K15918 GLYK; D-glycerate 3-kinase [EC:2.7.1.31] D Sphch_1966 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Sphch_1967 phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Sphch_0570 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D Sphch_0777 5-aminolevulinic acid synthase K00643 E2.3.1.37; 5-aminolevulinate synthase [EC:2.3.1.37] D Sphch_3959 L-amino-acid oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4] D Sphch_3967 L-amino-acid oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4] D Sphch_1411 glycine dehydrogenase (decarboxylating) subunit 1 K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2] D Sphch_1410 aminotransferase class V K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2] D Sphch_1413 glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D Sphch_1350 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_1064 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3288 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_1412 Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein D Sphch_1340 CDP-alcohol phosphatidyltransferase K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8] D Sphch_0254 L-serine dehydratase 1 K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D Sphch_1219 threonine dehydratase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D Sphch_0666 Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D Sphch_0667 Tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] C 00270 Cysteine and methionine metabolism [PATH:sch00270] D Sphch_0484 serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Sphch_1383 Serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Sphch_1111 Serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Sphch_1435 Cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47] D Sphch_3515 cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47] D Sphch_2468 cystathionine beta-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D Sphch_2811 Methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Sphch_2812 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Sphch_0189 S-adenosylmethionine synthase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D Sphch_2679 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9] D Sphch_3952 5-methylthioribose kinase K00899 mtnK; 5-methylthioribose kinase [EC:2.7.1.100] D Sphch_2293 Multi-copper polyphenol oxidoreductase, laccase K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] D Sphch_3951 Methylthioribose-1-phosphate isomerase K08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23] D Sphch_3955 Methylthioribulose-1-phosphate dehydratase K08964 mtnB; methylthioribulose-1-phosphate dehydratase [EC:4.2.1.109] D Sphch_3953 Enolase-phosphatase E1 K09880 mtnC; enolase-phosphatase E1 [EC:3.1.3.77] D Sphch_3954 Acireductone dioxygenase K08967 mtnD; 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase [EC:1.13.11.53 1.13.11.54] D Sphch_2266 Cys/Met metabolism pyridoxal-phosphate-dependent protein K01761 E4.4.1.11; methionine-gamma-lyase [EC:4.4.1.11] D Sphch_1215 putative GAF sensor protein K08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14] D Sphch_1987 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Sphch_2001 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Sphch_2414 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Sphch_0733 Adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D Sphch_1613 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Sphch_0740 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Sphch_2882 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Sphch_0292 Homoserine O-succinyltransferase K00651 metA; homoserine O-succinyltransferase/O-acetyltransferase [EC:2.3.1.46 2.3.1.31] D Sphch_2347 Homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] D Sphch_0372 O-succinylhomoserine sulfhydrylase K10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-] D Sphch_2020 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Sphch_2070 glutamate/cysteine ligase K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2] D Sphch_1708 Glutathione synthetase K01920 gshB; glutathione synthase [EC:6.3.2.3] D Sphch_1556 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Sphch_2469 3-mercaptopyruvate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Sphch_1354 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Sphch_0254 L-serine dehydratase 1 K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D Sphch_1966 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Sphch_1967 phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] C 00280 Valine, leucine and isoleucine degradation [PATH:sch00280] D Sphch_2020 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Sphch_1205 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4] D Sphch_3285 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4] D Sphch_1204 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4] D Sphch_3286 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4] D Sphch_3973 Pyruvate dehydrogenase (acetyl-transferring) K11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] D Sphch_3452 Pyruvate dehydrogenase (acetyl-transferring) K11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] D Sphch_1203 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] D Sphch_3287 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] D Sphch_1350 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_1064 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3288 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3509 Butyryl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_3822 Butyryl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_3365 (R)-benzylsuccinyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_3393 Long-chain-acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_0606 Butyryl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_0179 Long-chain-acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_2103 Butyryl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_3240 Long-chain-acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_0989 acyl-CoA dehydrogenase domain-containing protein K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7] D Sphch_1303 Isovaleryl-CoA dehydrogenase K00253 IVD; isovaleryl-CoA dehydrogenase [EC:1.3.8.4] D Sphch_1075 Enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D Sphch_0181 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_1081 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_2144 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_3243 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_4038 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_0760 Propionyl-CoA carboxylase K01965 PCCA; propionyl-CoA carboxylase alpha chain [EC:6.4.1.3] D Sphch_0764 Propionyl-CoA carboxylase K01966 PCCB; propionyl-CoA carboxylase beta chain [EC:6.4.1.3 2.1.3.15] D Sphch_0763 methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] D Sphch_3630 hypothetical protein K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] D Sphch_0762 methylmalonyl-CoA mutase, large subunit K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] D Sphch_1220 3-hydroxyisobutyrate dehydrogenase K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] D Sphch_1074 3-hydroxyisobutyrate dehydrogenase K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] D Sphch_3374 methylmalonate-semialdehyde dehydrogenase K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] D Sphch_0462 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_0986 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3619 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3249 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_0449 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48] D Sphch_1300 Methylcrotonoyl-CoA carboxylase K01968 MCCC1; 3-methylcrotonyl-CoA carboxylase alpha subunit [EC:6.4.1.4] D Sphch_1301 Methylcrotonoyl-CoA carboxylase K01969 MCCC2; 3-methylcrotonyl-CoA carboxylase beta subunit [EC:6.4.1.4] D Sphch_3872 Hydroxymethylglutaryl-CoA lyase K01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4] D Sphch_1033 3-oxoacid CoA-transferase, A subunit K01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5] D Sphch_3523 3-oxoacid CoA-transferase, A subunit K01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5] D Sphch_1034 3-oxoacid CoA-transferase, B subunit K01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5] D Sphch_3522 3-oxoacid CoA-transferase, B subunit K01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5] D Sphch_3998 acetoacetyl-CoA synthase K01907 AACS; acetoacetyl-CoA synthetase [EC:6.2.1.16] D Sphch_0612 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0180 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0094 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0995 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3248 acetyl-coenzyme A synthetase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_1080 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3982 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0756 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3830 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3834 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3054 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3883 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3885 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3931 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3997 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3506 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3670 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3497 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3386 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3831 protein of unknown function DUF35 K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:sch00290] D Sphch_1219 threonine dehydratase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D Sphch_2845 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Sphch_3291 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Sphch_3871 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Sphch_2847 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Sphch_3290 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Sphch_3870 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Sphch_0371 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D Sphch_3306 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D Sphch_0568 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Sphch_4067 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Sphch_3354 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Sphch_0566 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Sphch_0565 Ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D Sphch_2935 Dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D Sphch_2020 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Sphch_0563 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00300 Lysine biosynthesis [PATH:sch00300] D Sphch_2882 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Sphch_1613 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Sphch_0740 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Sphch_1790 Dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D Sphch_1021 Dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] D Sphch_1971 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117] D Sphch_2662 Acetylornithine/succinyldiaminopimelate aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Sphch_1891 Kynurenine--oxoglutarate transaminase K14267 dapC; N-succinyldiaminopimelate aminotransferase [EC:2.6.1.17] D Sphch_0011 Succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D Sphch_1642 Diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D Sphch_1239 pyridoxal-dependent decarboxylase, exosortase system type 1 associated K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D Sphch_1731 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D Sphch_1428 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D Sphch_1427 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] C 00310 Lysine degradation [PATH:sch00310] D Sphch_1351 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D Sphch_1350 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_1064 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3288 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3225 Glutaryl-CoA dehydrogenase K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6] D Sphch_1075 Enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D Sphch_0181 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_1081 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_0612 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0180 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0094 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0995 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3248 acetyl-coenzyme A synthetase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_1080 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3982 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0756 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3830 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3834 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3054 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3883 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3885 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3931 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3997 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3506 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3670 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3497 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3386 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0449 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48] D Sphch_0450 Succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3080 Betaine-aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3972 succinic semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_4065 succinic semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3471 Succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_0997 Formyl-CoA transferase K01041 gcdG; glutaryl-CoA transferase [EC:2.8.3.-] D Sphch_1918 D-amino-acid transaminase K00824 dat; D-alanine transaminase [EC:2.6.1.21] D Sphch_0462 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_0986 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3619 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3249 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00220 Arginine biosynthesis [PATH:sch00220] D Sphch_2663 Ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D Sphch_2601 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Sphch_1733 Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Sphch_0646 Glutaminase K01425 glsA; glutaminase [EC:3.5.1.2] D Sphch_0394 Phosphoribosylformylglycinamidine synthase 1 K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Sphch_1004 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Sphch_3112 NAD-glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2] D Sphch_3518 response regulator receiver protein K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] D Sphch_1556 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Sphch_0724 Arginine biosynthesis bifunctional protein ArgJ K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1] D Sphch_2825 acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8] D Sphch_0236 N-acetyl-gamma-glutamyl-phosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] D Sphch_2662 Acetylornithine/succinyldiaminopimelate aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Sphch_1856 acetylornithine deacetylase (ArgE) K01438 argE; acetylornithine deacetylase [EC:3.5.1.16] C 00330 Arginine and proline metabolism [PATH:sch00330] D Sphch_0620 Agmatine deiminase K10536 aguA; agmatine deiminase [EC:3.5.3.12] D Sphch_0619 N-carbamoylputrescine amidase K12251 aguB; N-carbamoylputrescine amidase [EC:3.5.1.53] D Sphch_0782 Ornithine decarboxylase K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17] D Sphch_0781 Orn/DAP/Arg decarboxylase 2 K13747 nspC; carboxynorspermidine decarboxylase [EC:4.1.1.96] D Sphch_0462 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_0986 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3619 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3249 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3959 L-amino-acid oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4] D Sphch_3967 L-amino-acid oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4] D Sphch_1848 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D Sphch_0814 arginine/ornithine succinyltransferase subunit K00673 astA; arginine N-succinyltransferase [EC:2.3.1.109] D Sphch_0815 N-succinylarginine dihydrolase K01484 astB; succinylarginine dihydrolase [EC:3.5.3.23] D Sphch_0280 succinylglutamic semialdehyde dehydrogenase K06447 astD; succinylglutamic semialdehyde dehydrogenase [EC:1.2.1.71] D Sphch_0436 FAD dependent oxidoreductase K09471 puuB; gamma-glutamylputrescine oxidase [EC:1.4.3.-] D Sphch_1855 Betaine-aldehyde dehydrogenase K09472 puuC; 4-(gamma-glutamylamino)butanal dehydrogenase [EC:1.2.1.99] D Sphch_1374 pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2] D Sphch_3483 delta-1-pyrroline-5-carboxylate dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88] D Sphch_2996 Glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D Sphch_2012 Gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] D Sphch_1756 proline iminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5] D Sphch_0026 Procollagen-proline dioxygenase K00472 P4HA; prolyl 4-hydroxylase [EC:1.14.11.2] D Sphch_1556 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Sphch_1918 D-amino-acid transaminase K00824 dat; D-alanine transaminase [EC:2.6.1.21] C 00340 Histidine metabolism [PATH:sch00340] D Sphch_2382 ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17] D Sphch_1965 tRNA synthetase class II (G H P and S) K02502 hisZ; ATP phosphoribosyltransferase regulatory subunit D Sphch_0303 Phosphoribosyl-ATP pyrophosphatase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31] D Sphch_0639 Phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19] D Sphch_0306 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D Sphch_0307 Imidazole glycerol phosphate synthase subunit hisH K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10] D Sphch_0305 Imidazole glycerol phosphate synthase subunit hisF K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10] D Sphch_0308 Imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19] D Sphch_2349 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_1603 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_1604 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_2336 histidinol-phosphate phosphatase K05602 hisN; histidinol-phosphatase [EC:3.1.3.15] D Sphch_2383 Histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23] D Sphch_0462 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_0986 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3619 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3249 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3959 L-amino-acid oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4] D Sphch_3967 L-amino-acid oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4] D Sphch_0040 methyltransferase K18911 egtD; L-histidine Nalpha-methyltransferase [EC:2.1.1.44] C 00350 Tyrosine metabolism [PATH:sch00350] D Sphch_1556 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Sphch_2349 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_1603 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_1604 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_3215 4-hydroxyphenylpyruvate dioxygenase K00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27] D Sphch_0441 Homogentisate 1,2-dioxygenase K00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5] D Sphch_3305 Homogentisate 1,2-dioxygenase K00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5] D Sphch_3716 Homogentisate 1,2-dioxygenase K00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5] D Sphch_3718 maleylacetoacetate isomerase K01800 maiA; maleylacetoacetate isomerase [EC:5.2.1.2] D Sphch_0443 maleylacetoacetate isomerase K01800 maiA; maleylacetoacetate isomerase [EC:5.2.1.2] D Sphch_3359 maleylacetoacetate isomerase K01800 maiA; maleylacetoacetate isomerase [EC:5.2.1.2] D Sphch_0442 fumarylacetoacetase K01555 FAH; fumarylacetoacetase [EC:3.7.1.2] D Sphch_3717 fumarylacetoacetase K01555 FAH; fumarylacetoacetase [EC:3.7.1.2] D Sphch_3959 L-amino-acid oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4] D Sphch_3967 L-amino-acid oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4] D Sphch_2126 Betaine-aldehyde dehydrogenase K00146 feaB; phenylacetaldehyde dehydrogenase [EC:1.2.1.39] D Sphch_0440 Phenylacetaldehyde dehydrogenase K00146 feaB; phenylacetaldehyde dehydrogenase [EC:1.2.1.39] D Sphch_3840 Alcohol dehydrogenase GroES domain protein K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D Sphch_3486 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D Sphch_0890 zinc-binding alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D Sphch_4197 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D Sphch_3900 oxidoreductase domain protein K10219 ligC; 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase [EC:1.1.1.312] D Sphch_0450 Succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3080 Betaine-aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3972 succinic semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_4065 succinic semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3471 Succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3848 Aryl-alcohol dehydrogenase K00055 E1.1.1.90; aryl-alcohol dehydrogenase [EC:1.1.1.90] D Sphch_3797 Aryl-alcohol dehydrogenase K00055 E1.1.1.90; aryl-alcohol dehydrogenase [EC:1.1.1.90] D Sphch_3357 gentisate 1,2-dioxygenase K00450 E1.13.11.4; gentisate 1,2-dioxygenase [EC:1.13.11.4] D Sphch_3358 fumarylacetoacetate (FAA) hydrolase K16165 nagK; fumarylpyruvate hydrolase [EC:3.7.1.20] C 00360 Phenylalanine metabolism [PATH:sch00360] D Sphch_3216 phenylalanine-4-hydroxylase K00500 phhA; phenylalanine-4-hydroxylase [EC:1.14.16.1] D Sphch_3959 L-amino-acid oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4] D Sphch_3967 L-amino-acid oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4] D Sphch_2126 Betaine-aldehyde dehydrogenase K00146 feaB; phenylacetaldehyde dehydrogenase [EC:1.2.1.39] D Sphch_0440 Phenylacetaldehyde dehydrogenase K00146 feaB; phenylacetaldehyde dehydrogenase [EC:1.2.1.39] D Sphch_0591 Enoyl-CoA hydratase/isomerase K15866 paaG; 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase [EC:5.3.3.18] D Sphch_0183 Enoyl-CoA hydratase/isomerase K15866 paaG; 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase [EC:5.3.3.18] D Sphch_2107 Enoyl-CoA hydratase/isomerase K15866 paaG; 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase [EC:5.3.3.18] D Sphch_3247 Enoyl-CoA hydratase/isomerase K15866 paaG; 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase [EC:5.3.3.18] D Sphch_3990 Enoyl-CoA hydratase K15866 paaG; 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase [EC:5.3.3.18] D Sphch_3503 Enoyl-CoA hydratase/isomerase K15866 paaG; 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase [EC:5.3.3.18] D Sphch_3669 Enoyl-CoA hydratase/isomerase K15866 paaG; 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase [EC:5.3.3.18] D Sphch_1075 Enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D Sphch_2045 3-hydroxybutyryl-CoA dehydrogenase K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] D Sphch_1556 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Sphch_2349 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_1603 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_1604 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_3848 Aryl-alcohol dehydrogenase K00055 E1.1.1.90; aryl-alcohol dehydrogenase [EC:1.1.1.90] D Sphch_3797 Aryl-alcohol dehydrogenase K00055 E1.1.1.90; aryl-alcohol dehydrogenase [EC:1.1.1.90] D Sphch_3215 4-hydroxyphenylpyruvate dioxygenase K00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27] D Sphch_1918 D-amino-acid transaminase K00824 dat; D-alanine transaminase [EC:2.6.1.21] D Sphch_3504 Catalase-peroxidase K03782 katG; catalase-peroxidase [EC:1.11.1.21] D Sphch_1848 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D Sphch_3944 Ferredoxin--NAD(+) reductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3] D Sphch_0328 Ferredoxin--NAD(+) reductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3] D Sphch_0445 monooxygenase FAD-binding protein K05712 mhpA; 3-(3-hydroxy-phenyl)propionate hydroxylase [EC:1.14.13.127] D Sphch_3082 2-keto-4-pentenoate hydratase-like protein K02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80] D Sphch_0679 2-oxopent-4-enoate hydratase K02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80] D Sphch_3493 4-hydroxy-2-oxovalerate aldolase K01666 mhpE; 4-hydroxy 2-oxovalerate aldolase [EC:4.1.3.39] D Sphch_3494 Acetaldehyde dehydrogenase K04073 mhpF; acetaldehyde dehydrogenase [EC:1.2.1.10] C 00380 Tryptophan metabolism [PATH:sch00380] D Sphch_1351 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D Sphch_1350 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_1064 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3288 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3225 Glutaryl-CoA dehydrogenase K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6] D Sphch_1075 Enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D Sphch_0181 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_1081 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_0612 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0180 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0094 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0995 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3248 acetyl-coenzyme A synthetase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_1080 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3982 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0756 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3830 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3834 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3054 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3883 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3885 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3931 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3997 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3506 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3670 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3497 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3386 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3959 L-amino-acid oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4] D Sphch_3967 L-amino-acid oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4] D Sphch_0462 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_0986 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3619 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3249 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_1848 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D Sphch_3012 Catalase K03781 katE; catalase [EC:1.11.1.6] D Sphch_3504 Catalase-peroxidase K03782 katG; catalase-peroxidase [EC:1.11.1.21] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:sch00400] D Sphch_1688 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D Sphch_1326 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4] D Sphch_1677 3-dehydroquinate dehydratase K03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10] D Sphch_2226 Shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] D Sphch_3281 membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family K05358 quiA; quinate dehydrogenase (quinone) [EC:1.1.5.8] D Sphch_1325 Shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71] D Sphch_0652 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D Sphch_1954 chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D Sphch_1263 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Sphch_1737 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D Sphch_1738 Anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18] D Sphch_0668 Phosphoribosylanthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24] D Sphch_1739 Indole-3-glycerol-phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48] D Sphch_0666 Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D Sphch_0667 Tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D Sphch_1398 chorismate mutase K04092 tyrA1; chorismate mutase [EC:5.4.99.5] D Sphch_2350 Prephenate dehydrogenase K00220 tyrC; cyclohexadieny/prephenate dehydrogenase [EC:1.3.1.43 1.3.1.12] D Sphch_2836 Prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51] D Sphch_1556 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Sphch_2349 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_1603 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_1604 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_3216 phenylalanine-4-hydroxylase K00500 phhA; phenylalanine-4-hydroxylase [EC:1.14.16.1] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism [PATH:sch00410] D Sphch_0449 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48] D Sphch_0462 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_0986 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3619 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3249 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_2221 Pantothenate synthetase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1] D Sphch_0459 amidase, hydantoinase/carbamoylase family K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87] D Sphch_1075 Enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D Sphch_0181 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_1081 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_3374 methylmalonate-semialdehyde dehydrogenase K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] C 00430 Taurine and hypotaurine metabolism [PATH:sch00430] D Sphch_3970 Gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Sphch_2035 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Sphch_2556 alanine dehydrogenase K00259 ald; alanine dehydrogenase [EC:1.4.1.1] D Sphch_3112 NAD-glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2] C 00440 Phosphonate and phosphinate metabolism D Sphch_0713 PhnP protein K06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55] C 00450 Selenocompound metabolism [PATH:sch00450] D Sphch_2468 cystathionine beta-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D Sphch_2811 Methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Sphch_2812 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Sphch_2266 Cys/Met metabolism pyridoxal-phosphate-dependent protein K01761 E4.4.1.11; methionine-gamma-lyase [EC:4.4.1.11] D Sphch_2027 cysteine desulfurase, SufS subfamily K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D Sphch_1264 thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D Sphch_3380 Sulfate adenylyltransferase subunit 1 K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25] D Sphch_3381 Sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4] D Sphch_0715 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism [PATH:sch00460] D Sphch_1290 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_1564 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_1862 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_2775 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_1289 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_3970 Gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Sphch_2035 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Sphch_1373 Asparaginase/glutaminase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D Sphch_3427 Asparaginase K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5] D Sphch_0626 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism [PATH:sch00470] D Sphch_0757 Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D Sphch_1918 D-amino-acid transaminase K00824 dat; D-alanine transaminase [EC:2.6.1.21] D Sphch_1419 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Sphch_0646 Glutaminase K01425 glsA; glutaminase [EC:3.5.1.2] D Sphch_0394 Phosphoribosylformylglycinamidine synthase 1 K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Sphch_0776 Glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D Sphch_1425 UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D Sphch_4058 Chloromuconate cycloisomerase K19802 ycjG; L-Ala-D/L-Glu epimerase / N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25] D Sphch_2892 Mandelate racemase/muconate lactonizing protein K19802 ycjG; L-Ala-D/L-Glu epimerase / N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25] D Sphch_2794 aspartate racemase K01779 racD; aspartate racemase [EC:5.1.1.13] D Sphch_1642 Diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D Sphch_1239 pyridoxal-dependent decarboxylase, exosortase system type 1 associated K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D Sphch_1731 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D Sphch_1363 FAD dependent oxidoreductase K19746 dauA; D-arginine dehydrogenase [EC:1.4.99.6] C 00480 Glutathione metabolism [PATH:sch00480] D Sphch_3970 Gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Sphch_2035 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Sphch_2070 glutamate/cysteine ligase K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2] D Sphch_1708 Glutathione synthetase K01920 gshB; glutathione synthase [EC:6.3.2.3] D Sphch_0239 peptidase M17 leucyl aminopeptidase domain protein K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D Sphch_1581 cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D Sphch_2259 aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] D Sphch_0221 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_3179 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_2017 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_2132 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_4048 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_4017 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_2844 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_1578 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_0490 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_0767 Glutathione-disulfide reductase K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7] D Sphch_3488 Glutathione-disulfide reductase K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7] D Sphch_1342 isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D Sphch_1088 glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D Sphch_1136 Peroxiredoxin K00432 gpx; glutathione peroxidase [EC:1.11.1.9] D Sphch_0736 Redoxin domain protein K24138 prx3; glutaredoxin/glutathione-dependent peroxiredoxin [EC:1.11.1.25 1.11.1.27] D Sphch_0782 Ornithine decarboxylase K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation C 00540 Lipopolysaccharide biosynthesis [PATH:sch00540] D Sphch_2558 KpsF/GutQ family protein K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13] D Sphch_2011 2-dehydro-3-deoxyphosphooctonate aldolase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55] D Sphch_2559 3-deoxy-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38] D Sphch_0669 lipid A biosynthesis acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-] D Sphch_2708 GHMP kinase K07031 hddA; D-glycero-alpha-D-manno-heptose-7-phosphate kinase [EC:2.7.1.168] C 00542 O-Antigen repeat unit biosynthesis C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:sch00541] D Sphch_0493 UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Sphch_2058 UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Sphch_1082 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Sphch_2176 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Sphch_3431 UDP-galactopyranose mutase K01854 glf; UDP-galactopyranose mutase [EC:5.4.99.9] D Sphch_0389 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Sphch_0982 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Sphch_2557 UDP-glucuronate 4-epimerase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] D Sphch_2689 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Sphch_2692 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D Sphch_2690 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D Sphch_2691 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] D Sphch_3430 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] D Sphch_1682 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D Sphch_2218 Phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8] D Sphch_1346 Bifunctional protein glmU K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D Sphch_0390 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D Sphch_0391 nucleotide sugar dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336] C 00550 Peptidoglycan biosynthesis [PATH:sch00550] D Sphch_1572 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D Sphch_1420 UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D Sphch_1422 UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D Sphch_1425 UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D Sphch_1428 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D Sphch_1419 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Sphch_1427 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D Sphch_1334 Undecaprenyl pyrophosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D Sphch_1903 Undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D Sphch_1426 Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D Sphch_1423 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D Sphch_1011 monofunctional biosynthetic peptidoglycan transglycosylase K03814 mtgA; monofunctional glycosyltransferase [EC:2.4.99.28] D Sphch_0029 Peptidoglycan glycosyltransferase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Sphch_1118 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Sphch_2246 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Sphch_0848 penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D Sphch_1429 Peptidoglycan glycosyltransferase K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D Sphch_0718 Serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C 00552 Teichoic acid biosynthesis [PATH:sch00552] D Sphch_1903 Undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D Sphch_0972 glycosyl transferase, WecB/TagA/CpsF family K05946 tagA; N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase [EC:2.4.1.187] C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis [PATH:sch00543] D Sphch_0482 glycosyl transferase group 1 K16703 wcaL; colanic acid/amylovoran/stewartan biosynthesis glycosyltransferase WcaL/AmsK/CpsK [EC:2.4.-.-] D Sphch_0492 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase K20997 pslA; polysaccharide biosynthesis protein PslA D Sphch_1228 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase K20997 pslA; polysaccharide biosynthesis protein PslA D Sphch_0965 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase K20997 pslA; polysaccharide biosynthesis protein PslA D Sphch_1231 sugar transferase, PEP-CTERM/EpsH1 system associated K21001 pslH; polysaccharide biosynthesis protein PslH D Sphch_0484 serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Sphch_1383 Serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Sphch_1111 Serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Sphch_0494 Oligosaccharide biosynthesis protein Alg14 like protein K25903 pssD; exopolysaccharide biosynthesis glucuronosyltransferase PssD D Sphch_0495 Glycosyltransferase 28 domain protein K25904 pssE; exopolysaccharide biosynthesis glucuronosyltransferase PssE B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:sch00730] D Sphch_2005 Phosphomethylpyrimidine synthase K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17] D Sphch_1467 phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7] D Sphch_0631 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Sphch_0632 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Sphch_1123 1-deoxy-D-xylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7] D Sphch_1676 Thiazole synthase K03149 thiG; thiazole synthase [EC:2.8.1.10] D Sphch_1191 Thiamine-phosphate pyrophosphorylase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3] D Sphch_2239 thiamine monophosphate synthase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3] D Sphch_2385 thiamine-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16] D Sphch_1808 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism [PATH:sch00740] D Sphch_2209 GTP cyclohydrolase-2 K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] D Sphch_2369 3,4-dihydroxy-2-butanone 4-phosphate synthase K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D Sphch_3063 3,4-dihydroxy-2-butanone 4-phosphate synthase K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D Sphch_2371 riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D Sphch_2368 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D Sphch_2370 riboflavin synthase, alpha subunit K00793 ribE; riboflavin synthase [EC:2.5.1.9] D Sphch_1129 riboflavin biosynthesis protein RibF K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D Sphch_1752 Acid phosphatase K09474 phoN; acid phosphatase (class A) [EC:3.1.3.2] D Sphch_3766 cob(II)yrinic acid a,c-diamide reductase K04719 bluB; 5,6-dimethylbenzimidazole synthase [EC:1.13.11.79] D Sphch_1662 NUDIX hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] C 00750 Vitamin B6 metabolism [PATH:sch00750] D Sphch_1958 Pyridoxine/pyridoxamine 5'-phosphate oxidase K00275 pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5] D Sphch_1967 phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Sphch_1584 4-hydroxythreonine-4-phosphate dehydrogenase K00097 pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase [EC:1.1.1.262] D Sphch_2453 Pyridoxine 5'-phosphate synthase K03474 pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2] D Sphch_2463 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] C 00760 Nicotinate and nicotinamide metabolism [PATH:sch00760] D Sphch_2815 L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16] D Sphch_1703 Quinolinate synthase A K03517 nadA; quinolinate synthase [EC:2.5.1.72] D Sphch_1702 nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D Sphch_0243 Multifunctional protein surE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Sphch_1914 nicotinate-nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] D Sphch_0709 MazG family protein K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9] D Sphch_2079 NUDIX hydrolase K03426 NUDT12_13; NAD+ diphosphatase [EC:3.6.1.22] D Sphch_2332 NAD+ synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5] D Sphch_0700 CinA domain protein K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42] D Sphch_0147 CinA domain protein K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42] D Sphch_1020 NAD-dependent deacetylase K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313] D Sphch_0516 inorganic polyphosphate/ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] D Sphch_3041 NAD(P) transhydrogenase subunit alpha K00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1] D Sphch_3042 NAD(P)(+) transhydrogenase (AB-specific) K00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1] D Sphch_2792 NAD(P) transhydrogenase alpha subunit K00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1] D Sphch_3040 NAD(P)(+) transhydrogenase (AB-specific) K00325 pntB; proton-translocating NAD(P)+ transhydrogenase subunit beta [EC:7.1.1.1] D Sphch_2793 NAD(P) transhydrogenase beta subunit K00325 pntB; proton-translocating NAD(P)+ transhydrogenase subunit beta [EC:7.1.1.1] D Sphch_0450 Succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3080 Betaine-aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3972 succinic semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_4065 succinic semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D Sphch_3471 Succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] C 00770 Pantothenate and CoA biosynthesis [PATH:sch00770] D Sphch_0568 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Sphch_4067 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Sphch_3354 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Sphch_0566 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Sphch_0565 Ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D Sphch_2935 Dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D Sphch_0058 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11] D Sphch_0685 2-dehydropantoate 2-reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169] D Sphch_2221 Pantothenate synthetase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1] D Sphch_1171 putative transcriptional acitvator, Baf family K03525 coaX; type III pantothenate kinase [EC:2.7.1.33] D Sphch_1596 phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] D Sphch_0709 MazG family protein K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9] D Sphch_1307 Phosphopantetheine adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D Sphch_2227 Dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24] D Sphch_2452 Holo-(acyl-carrier-protein) synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7] D Sphch_2020 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Sphch_0459 amidase, hydantoinase/carbamoylase family K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87] D Sphch_0462 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_0986 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3619 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3249 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] C 00780 Biotin metabolism [PATH:sch00780] D Sphch_1313 Methyltransferase type 11 K02169 bioC; malonyl-CoA O-methyltransferase [EC:2.1.1.197] D Sphch_0324 3-oxoacyl-(acyl-carrier-protein) synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D Sphch_0607 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_0322 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_3974 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_3566 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_3571 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_1328 (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D Sphch_1955 Enoyl-(acyl-carrier-protein) reductase (NADH) K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D Sphch_1405 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D Sphch_2388 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D Sphch_2392 Adenosylmethionine--8-amino-7-oxononanoate transaminase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62] D Sphch_2389 Dethiobiotin synthetase K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3] D Sphch_0761 Biotin synthase K01012 bioB; biotin synthase [EC:2.8.1.6] D Sphch_1172 biotin/acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism [PATH:sch00785] D Sphch_2670 Octanoyltransferase K03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181] D Sphch_0698 Lipoyl synthase K03644 lipA; lipoyl synthase [EC:2.8.1.8] D Sphch_1350 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_1064 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3288 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3447 Pyruvate dehydrogenase (acetyl-transferring) K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D Sphch_0553 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Sphch_3731 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Sphch_0554 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Sphch_3732 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Sphch_1066 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Sphch_3660 Dihydrolipoyllysine-residue acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Sphch_3446 Dihydrolipoyllysine-residue acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Sphch_1352 2-oxoglutarate dehydrogenase, E1 subunit K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] D Sphch_1351 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D Sphch_1205 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4] D Sphch_3285 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4] D Sphch_1204 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4] D Sphch_3286 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4] D Sphch_3973 Pyruvate dehydrogenase (acetyl-transferring) K11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] D Sphch_3452 Pyruvate dehydrogenase (acetyl-transferring) K11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] D Sphch_1203 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] D Sphch_3287 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] D Sphch_1411 glycine dehydrogenase (decarboxylating) subunit 1 K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2] D Sphch_1410 aminotransferase class V K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2] D Sphch_1413 glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D Sphch_1412 Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein C 00790 Folate biosynthesis [PATH:sch00790] D Sphch_1077 GTP cyclohydrolase 1 K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16] D Sphch_0616 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D Sphch_1450 dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15] D Sphch_1130 Dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D Sphch_0664 FolC bifunctional protein K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D Sphch_2209 GTP cyclohydrolase-2 K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] D Sphch_2369 3,4-dihydroxy-2-butanone 4-phosphate synthase K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D Sphch_3063 3,4-dihydroxy-2-butanone 4-phosphate synthase K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D Sphch_1558 para-aminobenzoate synthase, subunit I K01665 pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85] D Sphch_4015 para-aminobenzoate synthase, subunit I K01665 pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85] D Sphch_1557 aminotransferase class IV K02619 pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38] D Sphch_1925 6-pyruvoyl tetrahydropterin synthase and hypothetical protein K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D Sphch_0087 pterin-4-alpha-carbinolamine dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] D Sphch_3216 phenylalanine-4-hydroxylase K00500 phhA; phenylalanine-4-hydroxylase [EC:1.14.16.1] D Sphch_2667 Radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D Sphch_1926 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D Sphch_2666 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D Sphch_2471 NADPH-dependent 7-cyano-7-deazaguanine reductase K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13] D Sphch_0517 molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D Sphch_1740 molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D Sphch_1114 molybdopterin biosynthesis MoaE protein K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12] D Sphch_0792 molybdenum cofactor biosynthesis protein B K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D Sphch_1741 molybdenum cofactor synthesis domain protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] D Sphch_1078 MobA-related protein K07141 mocA; molybdenum cofactor cytidylyltransferase [EC:2.7.7.76] D Sphch_1716 Molybdopterin-guanine dinucleotide biosynthesis protein A K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77] C 00670 One carbon pool by folate [PATH:sch00670] D Sphch_1130 Dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D Sphch_2828 Bifunctional protein folD K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D Sphch_4022 Bifunctional protein folD K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D Sphch_0626 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Sphch_2818 phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D Sphch_2312 Bifunctional purine biosynthesis protein purH K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D Sphch_2189 Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D Sphch_1545 Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D Sphch_1413 glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D Sphch_2811 Methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Sphch_2812 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Sphch_1206 Thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] D Sphch_0428 formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10] D Sphch_4021 formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10] D Sphch_4031 methylenetetrahydrofolate reductase K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54] D Sphch_2810 5,10-methylenetetrahydrofolate reductase K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54] D Sphch_1199 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:sch00860] D Sphch_0777 5-aminolevulinic acid synthase K00643 E2.3.1.37; 5-aminolevulinate synthase [EC:2.3.1.37] D Sphch_1747 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Sphch_2331 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Sphch_1094 Porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D Sphch_2327 Porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61] D Sphch_2328 Uroporphyrinogen III synthase HEM4 K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] D Sphch_2223 Uroporphyrinogen decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37] D Sphch_2673 Coproporphyrinogen oxidase K00228 CPOX; coproporphyrinogen III oxidase [EC:1.3.3.3] D Sphch_3384 oxygen-independent coproporphyrinogen III oxidase K02495 hemN; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.98.3] D Sphch_0453 amine oxidase K00231 PPOX; protoporphyrinogen/coproporphyrinogen III oxidase [EC:1.3.3.4 1.3.3.15] D Sphch_2222 Uncharacterized protein family UPF0093 K08973 hemJ; protoporphyrinogen IX oxidase [EC:1.3.99.-] D Sphch_3123 Ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9] D Sphch_1730 siroheme synthase K02302 cysG; uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4] D Sphch_0279 uroporphyrin-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107] D Sphch_1717 uroporphyrin-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107] D Sphch_2457 Protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D Sphch_0080 Heme A synthase K02259 COX15; heme a synthase [EC:1.17.99.9] D Sphch_3763 precorrin-2 C20-methyltransferase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151] D Sphch_3765 precorrin-3B synthase K02229 cobG; precorrin-3B synthase [EC:1.14.13.83] D Sphch_3762 precorrin-3B C17-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272] D Sphch_3758 precorrin-4 C11-methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271] D Sphch_3759 cobalamin (vitamin B12) biosynthesis CbiG protein K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12] D Sphch_3756 precorrin-6A synthase (deacetylating) K02228 cobF; precorrin-6A synthase [EC:2.1.1.152] D Sphch_3761 precorrin-6x reductase K05895 cobK-cbiJ; precorrin-6A/cobalt-precorrin-6A reductase [EC:1.3.1.54 1.3.1.106] D Sphch_3760 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit K00595 cobL-cbiET; precorrin-6B C5,15-methyltransferase / cobalt-precorrin-6B C5,C15-methyltransferase [EC:2.1.1.132 2.1.1.289 2.1.1.196] D Sphch_3764 Precorrin-8X methylmutase K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60] D Sphch_3757 Cobyrinic acid A,C-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11] D Sphch_3768 cobaltochelatase, CobN subunit K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2] D Sphch_2359 cobalt chelatase, pCobS small subunit K09882 cobS; cobaltochelatase CobS [EC:6.6.1.2] D Sphch_2362 cobalt chelatase, pCobT subunit K09883 cobT; cobaltochelatase CobT [EC:6.6.1.2] D Sphch_0043 ATP/cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D Sphch_3767 cob(I)alamin adenosyltransferase K19221 cobA; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D Sphch_0817 Cobyric acid synthase K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10] D Sphch_3744 Cobalamin biosynthesis protein cbiB K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10] D Sphch_3743 L-threonine-O-3-phosphate decarboxylase K02225 cobC1; cobalamin biosynthesis protein CobC D Sphch_3745 Adenosylcobinamide-phosphate guanylyltransferase K02231 cobP; adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.1.156 2.7.7.62] D Sphch_3742 Cobalamin synthase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26] D Sphch_3740 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase K00768 E2.4.2.21; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [EC:2.4.2.21] D Sphch_3741 Phosphoglycerate mutase K02226 cobC; alpha-ribazole phosphatase [EC:3.1.3.73] D Sphch_1316 bacterioferritin K03594 bfr; bacterioferritin [EC:1.16.3.1] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:sch00130] D Sphch_2072 4-hydroxybenzoate polyprenyl transferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] D Sphch_1614 ubiquinone biosynthesis O-methyltransferase K00568 ubiG; 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase [EC:2.1.1.222 2.1.1.64] D Sphch_2019 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family K03185 ubiH; 2-octaprenyl-6-methoxyphenol hydroxylase [EC:1.14.13.-] D Sphch_2915 Ubiquinone/menaquinone biosynthesis methyltransferase ubiE K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201] D Sphch_1908 ubiquinone biosynthesis monooxygenase COQ7 K06134 COQ7; 3-demethoxyubiquinol 3-hydroxylase [EC:1.14.99.60] D Sphch_0258 Flavoprotein wrbA K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] D Sphch_2507 flavodoxin/nitric oxide synthase K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] D Sphch_3215 4-hydroxyphenylpyruvate dioxygenase K00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27] B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:sch00900] D Sphch_1123 1-deoxy-D-xylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7] D Sphch_1332 1-deoxy-D-xylulose 5-phosphate reductoisomerase K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267] D Sphch_0701 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K12506 ispDF; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:2.7.7.60 4.6.1.12] D Sphch_0787 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148] D Sphch_2216 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3] D Sphch_1447 4-hydroxy-3-methylbut-2-enyl diphosphate reductase K03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] D Sphch_0612 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0180 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0094 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0995 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3248 acetyl-coenzyme A synthetase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_1080 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3982 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0756 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3830 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3834 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3054 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3883 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3885 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3931 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3997 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3506 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3670 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3497 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3386 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3831 protein of unknown function DUF35 K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D Sphch_1308 Farnesyltranstransferase K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] D Sphch_1399 Trans-hexaprenyltranstransferase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90] D Sphch_1334 Undecaprenyl pyrophosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis [PATH:sch00906] D Sphch_1941 Phytoene synthase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32] D Sphch_1943 phytoene desaturase K10027 crtI; phytoene desaturase [EC:1.3.99.26 1.3.99.28 1.3.99.29 1.3.99.31] D Sphch_1944 lycopene cyclase K06443 lcyB; lycopene beta-cyclase [EC:5.5.1.19] D Sphch_2465 fatty acid hydroxylase K15746 crtZ; beta-carotene 3-hydroxylase [EC:1.14.15.24] C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation [PATH:sch00903] D Sphch_0462 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_0986 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3619 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3249 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3345 Limonene-12-epoxide hydrolase K10533 E3.3.2.8; limonene-1,2-epoxide hydrolase [EC:3.3.2.8] C 00907 Pinene, camphor and geraniol degradation [PATH:sch00907] D Sphch_1075 Enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D Sphch_0181 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_1081 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_3071 Phenylacetone monooxygenase K21730 otemo; (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase [EC:1.14.13.160] D Sphch_3057 Luciferase-like, subgroup K23020 camE36; 3,6-diketocamphane 1,6-monooxygenase [EC:1.14.14.155] D Sphch_3872 Hydroxymethylglutaryl-CoA lyase K01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4] D Sphch_2144 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_3243 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_4038 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D Sphch_1196 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis [PATH:sch00523] D Sphch_2689 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Sphch_2692 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D Sphch_2690 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D Sphch_2691 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] D Sphch_3430 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 01054 Nonribosomal peptide structures [PATH:sch01054] D Sphch_2794 aspartate racemase K01779 racD; aspartate racemase [EC:5.1.1.13] C 01053 Biosynthesis of siderophore group nonribosomal peptides D Sphch_0623 Chorismate mutase, type II K04782 pchB; isochorismate pyruvate lyase [EC:4.2.99.21] C 01055 Biosynthesis of vancomycin group antibiotics D Sphch_2692 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids [PATH:sch00946] D Sphch_1290 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_1564 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_1862 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_2775 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_1289 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids [PATH:sch00996] D Sphch_3903 Enoyl-CoA hydratase/isomerase K18383 ferB; feruloyl-CoA hydratase/lyase [EC:4.1.2.61] C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis D Sphch_2614 Beta-lactamase K17836 penP; beta-lactamase class A [EC:3.5.2.6] D Sphch_2813 Beta-lactamase K17836 penP; beta-lactamase class A [EC:3.5.2.6] D Sphch_0634 Beta-lactamase K17836 penP; beta-lactamase class A [EC:3.5.2.6] C 00332 Carbapenem biosynthesis [PATH:sch00332] D Sphch_2996 Glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D Sphch_2012 Gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] C 00261 Monobactam biosynthesis [PATH:sch00261] D Sphch_3380 Sulfate adenylyltransferase subunit 1 K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25] D Sphch_3381 Sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4] D Sphch_1613 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Sphch_0740 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Sphch_1790 Dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D Sphch_1021 Dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:sch00521] D Sphch_1090 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Sphch_1187 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Sphch_2081 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Sphch_2689 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Sphch_2692 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D Sphch_2690 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D Sphch_2691 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] D Sphch_3430 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 00524 Neomycin, kanamycin and gentamicin biosynthesis D Sphch_1090 glucokinase K00845 glk; glucokinase [EC:2.7.1.2] C 00525 Acarbose and validamycin biosynthesis [PATH:sch00525] D Sphch_2689 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Sphch_2692 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] C 00401 Novobiocin biosynthesis [PATH:sch00401] D Sphch_2350 Prephenate dehydrogenase K00220 tyrC; cyclohexadieny/prephenate dehydrogenase [EC:1.3.1.43 1.3.1.12] D Sphch_1556 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Sphch_2349 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_1603 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_1604 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D Sphch_1263 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Sphch_1737 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis D Sphch_0320 malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D Sphch_0607 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_0322 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_3974 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_3566 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_3571 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_1955 Enoyl-(acyl-carrier-protein) reductase (NADH) K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics D Sphch_0323 acyl carrier protein K02078 acpP; acyl carrier protein D Sphch_1242 hypothetical protein K02078 acpP; acyl carrier protein D Sphch_1404 phosphopantetheine-binding protein K02078 acpP; acyl carrier protein C 00999 Biosynthesis of various plant secondary metabolites [PATH:sch00999] D Sphch_0189 S-adenosylmethionine synthase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D Sphch_2226 Shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] D Sphch_1290 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_1564 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_1862 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_2775 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Sphch_1289 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation [PATH:sch00362] D Sphch_3491 3-oxoacid CoA-transferase, A subunit K01031 pcaI; 3-oxoadipate CoA-transferase, alpha subunit [EC:2.8.3.6] D Sphch_3490 3-oxoacid CoA-transferase, B subunit K01032 pcaJ; 3-oxoadipate CoA-transferase, beta subunit [EC:2.8.3.6] D Sphch_2144 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_3243 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_4038 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_3489 beta-ketoadipyl CoA thiolase K07823 pcaF; 3-oxoadipyl-CoA thiolase [EC:2.3.1.174] D Sphch_3082 2-keto-4-pentenoate hydratase-like protein K02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80] D Sphch_0679 2-oxopent-4-enoate hydratase K02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80] D Sphch_3493 4-hydroxy-2-oxovalerate aldolase K01666 mhpE; 4-hydroxy 2-oxovalerate aldolase [EC:4.1.3.39] D Sphch_3494 Acetaldehyde dehydrogenase K04073 mhpF; acetaldehyde dehydrogenase [EC:1.2.1.10] D Sphch_1255 4-oxalocrotonate tautomerase family enzyme K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D Sphch_4045 Hydroxyquinol 1,2-dioxygenase K04098 chqB; hydroxyquinol 1,2-dioxygenase [EC:1.13.11.37] D Sphch_2527 Hydroxyquinol 1,2-dioxygenase K04098 chqB; hydroxyquinol 1,2-dioxygenase [EC:1.13.11.37] D Sphch_4020 Maleylacetate reductase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32] D Sphch_2528 Maleylacetate reductase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32] D Sphch_3044 Maleylacetate reductase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32] D Sphch_4069 Carboxymuconolactone decarboxylase K01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44] D Sphch_3560 Carboxymuconolactone decarboxylase K01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44] D Sphch_3632 Carboxymuconolactone decarboxylase K01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44] D Sphch_2926 Carboxymuconolactone decarboxylase K01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44] D Sphch_3898 protocatechuate 4,5-dioxygenase, alpha subunit K04100 ligA; protocatechuate 4,5-dioxygenase, alpha chain [EC:1.13.11.8] D Sphch_3899 Protocatechuate 4,5-dioxygenase K04101 ligB; protocatechuate 4,5-dioxygenase, beta chain [EC:1.13.11.8] D Sphch_3900 oxidoreductase domain protein K10219 ligC; 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase [EC:1.1.1.312] D Sphch_3897 amidohydrolase 2 K10221 ligI; 2-pyrone-4,6-dicarboxylate lactonase [EC:3.1.1.57] D Sphch_3892 PrpF protein K16514 galD; 4-oxalomesaconate tautomerase [EC:5.3.2.8] D Sphch_3896 amidohydrolase 2 K10220 ligJ; 4-oxalmesaconate hydratase [EC:4.2.1.83] D Sphch_3893 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase K10218 ligK; 4-hydroxy-4-methyl-2-oxoglutarate aldolase [EC:4.1.3.17] D Sphch_3292 cytochrome P450 K22553 CYP199A2; 4-methoxybenzoate monooxygenase (O-demethylating) [EC:1.14.99.15] D Sphch_3922 4-hydroxybenzoate 3-monooxygenase K00481 pobA; p-hydroxybenzoate 3-monooxygenase [EC:1.14.13.2] D Sphch_3654 3-oxoacyl-(acyl-carrier-protein) reductase K07535 badH; 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase [EC:1.1.1.-] D Sphch_0181 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_1081 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_0602 3-hydroxybutyryl-CoA epimerase K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] D Sphch_0101 3-hydroxybutyryl-CoA epimerase K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] D Sphch_2113 3-hydroxybutyryl-CoA epimerase K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] D Sphch_3642 3-hydroxybutyryl-CoA epimerase K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] D Sphch_3390 3-hydroxybutyryl-CoA epimerase K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] D Sphch_3225 Glutaryl-CoA dehydrogenase K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6] D Sphch_1075 Enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D Sphch_2045 3-hydroxybutyryl-CoA dehydrogenase K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] D Sphch_0612 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0180 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0094 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0995 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3248 acetyl-coenzyme A synthetase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_1080 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3982 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0756 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3830 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3834 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3054 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3883 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3885 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3931 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3997 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3506 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3670 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3497 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3386 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00627 Aminobenzoate degradation [PATH:sch00627] D Sphch_1848 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] D Sphch_0695 Acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D Sphch_2158 Phthalate 4,5-dioxygenase K03863 vanB; vanillate monooxygenase ferredoxin subunit D Sphch_4032 glycine cleavage T protein (aminomethyl transferase) K15066 ligM; vanillate/3-O-methylgallate O-demethylase [EC:2.1.1.341] D Sphch_3898 protocatechuate 4,5-dioxygenase, alpha subunit K04100 ligA; protocatechuate 4,5-dioxygenase, alpha chain [EC:1.13.11.8] D Sphch_3899 Protocatechuate 4,5-dioxygenase K04101 ligB; protocatechuate 4,5-dioxygenase, beta chain [EC:1.13.11.8] D Sphch_3900 oxidoreductase domain protein K10219 ligC; 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase [EC:1.1.1.312] D Sphch_3897 amidohydrolase 2 K10221 ligI; 2-pyrone-4,6-dicarboxylate lactonase [EC:3.1.1.57] D Sphch_1075 Enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] C 00364 Fluorobenzoate degradation [PATH:sch00364] D Sphch_2252 Carboxymethylenebutenolidase K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45] D Sphch_1776 Carboxymethylenebutenolidase K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45] D Sphch_3461 Pentachlorophenol monooxygenase K03391 pcpB; pentachlorophenol monooxygenase [EC:1.14.13.50] D Sphch_4020 Maleylacetate reductase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32] D Sphch_2528 Maleylacetate reductase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32] D Sphch_3044 Maleylacetate reductase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32] C 00625 Chloroalkane and chloroalkene degradation [PATH:sch00625] D Sphch_0890 zinc-binding alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D Sphch_4197 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D Sphch_3840 Alcohol dehydrogenase GroES domain protein K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D Sphch_3486 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D Sphch_0462 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_0986 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3619 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_3249 Betaine-aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] D Sphch_2868 HAD-superfamily hydrolase, subfamily IA, variant 3 K01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2] C 00361 Chlorocyclohexane and chlorobenzene degradation [PATH:sch00361] D Sphch_2252 Carboxymethylenebutenolidase K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45] D Sphch_1776 Carboxymethylenebutenolidase K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45] D Sphch_3461 Pentachlorophenol monooxygenase K03391 pcpB; pentachlorophenol monooxygenase [EC:1.14.13.50] D Sphch_3460 Phthalate 4,5-dioxygenase K21607 pcpD; tetrachlorobenzoquinone reductase [EC:1.1.1.404] D Sphch_4028 Glutathione S-transferase domain protein K15241 pcpC; tetrachlorohydroquinone reductive dehalogenase [EC:1.21.4.5] D Sphch_4024 Glyoxalase/bleomycin resistance protein/dioxygenase K15242 pcpA; 2,6-dichloro-p-hydroquinone 1,2-dioxygenase [EC:1.13.11.-] D Sphch_4020 Maleylacetate reductase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32] D Sphch_2528 Maleylacetate reductase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32] D Sphch_3044 Maleylacetate reductase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32] D Sphch_4045 Hydroxyquinol 1,2-dioxygenase K04098 chqB; hydroxyquinol 1,2-dioxygenase [EC:1.13.11.37] D Sphch_2527 Hydroxyquinol 1,2-dioxygenase K04098 chqB; hydroxyquinol 1,2-dioxygenase [EC:1.13.11.37] D Sphch_4066 Taurine catabolism dioxygenase TauD/TfdA K06912 tfdA; alpha-ketoglutarate-dependent 2,4-dichlorophenoxyacetate dioxygenase [EC:1.14.11.-] D Sphch_2868 HAD-superfamily hydrolase, subfamily IA, variant 3 K01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2] C 00623 Toluene degradation [PATH:sch00623] D Sphch_3848 Aryl-alcohol dehydrogenase K00055 E1.1.1.90; aryl-alcohol dehydrogenase [EC:1.1.1.90] D Sphch_3797 Aryl-alcohol dehydrogenase K00055 E1.1.1.90; aryl-alcohol dehydrogenase [EC:1.1.1.90] D Sphch_2252 Carboxymethylenebutenolidase K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45] D Sphch_1776 Carboxymethylenebutenolidase K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45] D Sphch_4020 Maleylacetate reductase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32] D Sphch_2528 Maleylacetate reductase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32] D Sphch_3044 Maleylacetate reductase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32] C 00622 Xylene degradation [PATH:sch00622] D Sphch_3848 Aryl-alcohol dehydrogenase K00055 E1.1.1.90; aryl-alcohol dehydrogenase [EC:1.1.1.90] D Sphch_3797 Aryl-alcohol dehydrogenase K00055 E1.1.1.90; aryl-alcohol dehydrogenase [EC:1.1.1.90] D Sphch_1255 4-oxalocrotonate tautomerase family enzyme K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D Sphch_3082 2-keto-4-pentenoate hydratase-like protein K02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80] D Sphch_0679 2-oxopent-4-enoate hydratase K02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80] D Sphch_3493 4-hydroxy-2-oxovalerate aldolase K01666 mhpE; 4-hydroxy 2-oxovalerate aldolase [EC:4.1.3.39] D Sphch_3494 Acetaldehyde dehydrogenase K04073 mhpF; acetaldehyde dehydrogenase [EC:1.2.1.10] C 00633 Nitrotoluene degradation [PATH:sch00633] D Sphch_3279 12-oxophytodienoate reductase K10680 nemA; N-ethylmaleimide reductase [EC:1.-.-.-] D Sphch_3473 12-oxophytodienoate reductase K10680 nemA; N-ethylmaleimide reductase [EC:1.-.-.-] D Sphch_3434 12-oxophytodienoate reductase K10680 nemA; N-ethylmaleimide reductase [EC:1.-.-.-] D Sphch_2297 12-oxophytodienoate reductase K10680 nemA; N-ethylmaleimide reductase [EC:1.-.-.-] C 00642 Ethylbenzene degradation [PATH:sch00642] D Sphch_2144 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_3243 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_4038 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D Sphch_3437 3-phenylpropanoate dioxygenase K14748 etbAa; ethylbenzene dioxygenase subunit alpha [EC:1.14.12.-] D Sphch_3438 Biphenyl 2,3-dioxygenase K14749 etbAb; ethylbenzene dioxygenase subunit beta [EC:1.14.12.-] D Sphch_3441 2,6-dioxo-6-phenylhexa-3-enoate hydrolase K18092 etbD; 2-hydroxy-6-oxo-octa-2,4-dienoate hydrolase [EC:3.7.1.-] C 00643 Styrene degradation [PATH:sch00643] D Sphch_2126 Betaine-aldehyde dehydrogenase K00146 feaB; phenylacetaldehyde dehydrogenase [EC:1.2.1.39] D Sphch_0440 Phenylacetaldehyde dehydrogenase K00146 feaB; phenylacetaldehyde dehydrogenase [EC:1.2.1.39] D Sphch_0441 Homogentisate 1,2-dioxygenase K00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5] D Sphch_3305 Homogentisate 1,2-dioxygenase K00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5] D Sphch_3716 Homogentisate 1,2-dioxygenase K00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5] D Sphch_3718 maleylacetoacetate isomerase K01800 maiA; maleylacetoacetate isomerase [EC:5.2.1.2] D Sphch_0443 maleylacetoacetate isomerase K01800 maiA; maleylacetoacetate isomerase [EC:5.2.1.2] D Sphch_3359 maleylacetoacetate isomerase K01800 maiA; maleylacetoacetate isomerase [EC:5.2.1.2] D Sphch_0442 fumarylacetoacetase K01555 FAH; fumarylacetoacetase [EC:3.7.1.2] D Sphch_3717 fumarylacetoacetase K01555 FAH; fumarylacetoacetase [EC:3.7.1.2] D Sphch_1848 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4] C 00791 Atrazine degradation C 00930 Caprolactam degradation [PATH:sch00930] D Sphch_4060 Strictosidine synthase, conserved region K01053 gnl; gluconolactonase [EC:3.1.1.17] D Sphch_3563 SMP-30/Gluconolaconase/LRE-like region-containing protein K01053 gnl; gluconolactonase [EC:3.1.1.17] D Sphch_0599 SMP-30/Gluconolaconase/LRE-like region-containing protein K01053 gnl; gluconolactonase [EC:3.1.1.17] D Sphch_3829 Acyl-CoA dehydrogenase K06446 DCAA; acyl-CoA dehydrogenase [EC:1.3.99.-] D Sphch_0994 Butyryl-CoA dehydrogenase K06446 DCAA; acyl-CoA dehydrogenase [EC:1.3.99.-] D Sphch_1075 Enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17] D Sphch_0181 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] D Sphch_1081 3-hydroxybutyryl-CoA epimerase K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] C 00363 Bisphenol degradation D Sphch_3468 4-hydroxyacetophenone monooxygenase K14520 hapE; 4-hydroxyacetophenone monooxygenase [EC:1.14.13.84] C 00621 Dioxin degradation [PATH:sch00621] D Sphch_1255 4-oxalocrotonate tautomerase family enzyme K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D Sphch_3082 2-keto-4-pentenoate hydratase-like protein K02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80] D Sphch_0679 2-oxopent-4-enoate hydratase K02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80] D Sphch_3493 4-hydroxy-2-oxovalerate aldolase K01666 mhpE; 4-hydroxy 2-oxovalerate aldolase [EC:4.1.3.39] D Sphch_3494 Acetaldehyde dehydrogenase K04073 mhpF; acetaldehyde dehydrogenase [EC:1.2.1.10] C 00626 Naphthalene degradation [PATH:sch00626] D Sphch_0890 zinc-binding alcohol dehydrogenase family protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D Sphch_4197 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D Sphch_3840 Alcohol dehydrogenase GroES domain protein K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D Sphch_3486 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] C 00624 Polycyclic aromatic hydrocarbon degradation D Sphch_3898 protocatechuate 4,5-dioxygenase, alpha subunit K04100 ligA; protocatechuate 4,5-dioxygenase, alpha chain [EC:1.13.11.8] D Sphch_3899 Protocatechuate 4,5-dioxygenase K04101 ligB; protocatechuate 4,5-dioxygenase, beta chain [EC:1.13.11.8] C 00365 Furfural degradation [PATH:sch00365] D Sphch_3353 Choline dehydrogenase K16873 hmfH; 5-(hydroxymethyl)furfural/furfural oxidase [EC:1.1.3.47 1.1.3.-] C 00984 Steroid degradation [PATH:sch00984] D Sphch_3645 fumarate reductase/succinate dehydrogenase flavoprotein domain protein K05898 kstD; 3-oxosteroid 1-dehydrogenase [EC:1.3.99.4] D Sphch_3246 flavin reductase domain protein FMN-binding protein K16048 hsaB; 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase reductase component [EC:1.5.1.-] D Sphch_2201 flavin reductase domain protein FMN-binding protein K16048 hsaB; 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase reductase component [EC:1.5.1.-] D Sphch_3065 flavin reductase domain protein FMN-binding protein K16048 hsaB; 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase reductase component [EC:1.5.1.-] D Sphch_3617 Long-chain-fatty-acid--CoA ligase K18687 fadD3; HIP---CoA ligase [EC:6.2.1.41] D Sphch_3631 Long-chain-fatty-acid--CoA ligase K18687 fadD3; HIP---CoA ligase [EC:6.2.1.41] C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:sch03020] D Sphch_3135 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D Sphch_3136 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D Sphch_1872 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D Sphch_2480 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] C 03022 Basal transcription factors C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:sch03010] D Sphch_0649 ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1 D Sphch_1338 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D Sphch_1823 ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D Sphch_0622 ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D Sphch_1812 ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D Sphch_0317 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D Sphch_1833 ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D Sphch_1815 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D Sphch_0082 ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D Sphch_1830 ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D Sphch_1871 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D Sphch_1834 ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D Sphch_1870 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D Sphch_1816 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D Sphch_1248 ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D Sphch_1638 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D Sphch_1820 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D Sphch_0316 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D Sphch_1825 ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D Sphch_2917 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D Sphch_2448 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D Sphch_2987 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D Sphch_1826 ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D Sphch_1829 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D Sphch_1828 ribosomal protein L4/L1e K02926 RP-L4; large subunit ribosomal protein L4 D Sphch_1817 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Sphch_1814 ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D Sphch_2795 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D Sphch_0315 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D Sphch_2796 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D Sphch_2986 ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Sphch_0081 ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D Sphch_1819 ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D Sphch_1810 ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D Sphch_1822 ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D Sphch_1873 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D Sphch_1813 ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D Sphch_1634 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D Sphch_2338 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D Sphch_2992 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D Sphch_1824 ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D Sphch_1827 Ribosomal protein L25/L23 K02892 RP-L23; large subunit ribosomal protein L23 D Sphch_1818 ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D Sphch_0835 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25 D Sphch_2993 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D Sphch_2805 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D Sphch_1821 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Sphch_1811 ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D Sphch_1327 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D Sphch_2309 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D Sphch_2367 ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D Sphch_2911 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D Sphch_2337 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D Sphch_2869 ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 D Sphch_R0043 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Sphch_R0058 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Sphch_R0067 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Sphch_R0046 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Sphch_R0061 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Sphch_R0064 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Sphch_R0047 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Sphch_R0062 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Sphch_R0063 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:sch00970] D Sphch_R0045 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Sphch_R0060 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Sphch_R0065 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Sphch_R0009 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Sphch_R0010 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Sphch_R0028 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Sphch_R0020 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Sphch_R0029 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Sphch_R0030 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Sphch_R0015 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Sphch_R0016 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Sphch_R0003 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Sphch_R0004 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Sphch_R0024 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Sphch_R0025 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Sphch_R0032 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Sphch_R0057 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Sphch_R0055 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Sphch_R0001 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Sphch_R0034 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Sphch_R0022 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Sphch_R0052 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Sphch_R0040 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Sphch_R0007 tRNA-His K14226 tRNA-His; tRNA His D Sphch_R0044 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Sphch_R0066 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Sphch_R0059 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Sphch_R0019 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Sphch_R0021 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Sphch_R0036 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Sphch_R0041 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Sphch_R0008 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Sphch_R0005 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Sphch_R0017 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Sphch_R0018 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Sphch_R0027 tRNA-Met K14230 tRNA-Met; tRNA Met D Sphch_R0011 tRNA-Met K14230 tRNA-Met; tRNA Met D Sphch_R0048 tRNA-Met K14230 tRNA-Met; tRNA Met D Sphch_R0049 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Sphch_R0026 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Sphch_R0012 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Sphch_R0035 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Sphch_R0013 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Sphch_R0042 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Sphch_R0050 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Sphch_R0051 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Sphch_R0056 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Sphch_R0038 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Sphch_R0039 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Sphch_R0002 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Sphch_R0054 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Sphch_R0031 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Sphch_R0053 tRNA-Val K14237 tRNA-Val; tRNA Val D Sphch_R0014 tRNA-Val K14237 tRNA-Val; tRNA Val D Sphch_R0037 tRNA-Val K14237 tRNA-Val; tRNA Val D Sphch_1747 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Sphch_2331 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Sphch_0574 Glutamyl-tRNA(Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D Sphch_0575 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Sphch_0573 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D Sphch_0645 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Sphch_1796 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Sphch_0832 Glycyl-tRNA synthetase alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D Sphch_0831 Glycyl-tRNA synthetase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D Sphch_1591 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Sphch_0244 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Sphch_1686 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Sphch_0715 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Sphch_2189 Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D Sphch_1545 Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D Sphch_0048 Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Sphch_2242 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Sphch_1128 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Sphch_0021 lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Sphch_1445 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Sphch_0753 Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Sphch_2284 Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Sphch_2340 Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Sphch_2341 Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Sphch_0526 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Sphch_0004 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:sch03060] D Sphch_1809 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Sphch_2984 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Sphch_1260 preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Sphch_1842 protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD D Sphch_1841 protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF D Sphch_1843 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Sphch_2908 Membrane protein oxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase D Sphch_0723 Protein translocase subunit secA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Sphch_0006 Protein-export protein secB K03071 secB; preprotein translocase subunit SecB D Sphch_1639 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Sphch_R0006 ffs; SRP RNA; RNA component of signal recognition particle K01983 ffs; SRP RNA D Sphch_1644 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Sphch_1440 Sec-independent protein translocase protein tatA/E-like protein K03116 tatA; sec-independent protein translocase protein TatA D Sphch_1439 twin-arginine translocation protein, TatB subunit K03117 tatB; sec-independent protein translocase protein TatB D Sphch_1438 Sec-independent protein translocase, TatC subunit K03118 tatC; sec-independent protein translocase protein TatC D Sphch_0769 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D Sphch_2451 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D Sphch_1127 Lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:sch04122] D Sphch_0631 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Sphch_0632 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Sphch_2469 3-mercaptopyruvate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D Sphch_0054 putative redox protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D Sphch_2381 tRNA-specific 2-thiouridylase mnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D Sphch_1114 molybdopterin biosynthesis MoaE protein K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12] D Sphch_0517 molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D Sphch_1115 molybdopterin converting factor, subunit 1 K03636 moaD; sulfur-carrier protein D Sphch_1594 UBA/THIF-type NAD/FAD binding protein K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80] D Sphch_0953 PRTRC system ThiF family protein K21147 moeZR; sulfur-carrier protein adenylyltransferase/sulfurtransferase [EC:2.7.7.80 2.7.7.- 2.8.1.11 2.8.1.-] D Sphch_1740 molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D Sphch_0792 molybdenum cofactor biosynthesis protein B K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] C 03050 Proteasome C 03018 RNA degradation [PATH:sch03018] D Sphch_0811 RNA pyrophosphohydrolase K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-] D Sphch_0027 ribonuclease, Rne/Rng family K08300 rne; ribonuclease E [EC:3.1.26.12] D Sphch_0551 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Sphch_1247 Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D Sphch_1050 DEAD/DEAH box helicase domain protein K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] D Sphch_0421 ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] D Sphch_2988 DEAD/DEAH box helicase domain protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Sphch_1950 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D Sphch_2248 transcription termination factor Rho K03628 rho; transcription termination factor Rho D Sphch_1170 RNA-metabolising metallo-beta-lactamase K12574 rnj; ribonuclease J [EC:3.1.-.-] D Sphch_2944 Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK D Sphch_2487 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Sphch_0707 Protein hfq K03666 hfq; host factor-I protein D Sphch_2822 Polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] D Sphch_0405 Polynucleotide adenylyltransferase region K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] B B 09124 Replication and repair C 03030 DNA replication [PATH:sch03030] D Sphch_2228 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Sphch_0794 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Sphch_0635 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Sphch_0716 DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Sphch_2244 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Sphch_1580 DNA polymerase III chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] D Sphch_1759 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Sphch_0273 replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D Sphch_0537 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D Sphch_2301 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Sphch_4134 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Sphch_4121 single-strand binding protein/Primosomal replication protein n K03111 ssb; single-strand DNA-binding protein D Sphch_1449 Ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D Sphch_1466 Ribonuclease H K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Sphch_1681 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Sphch_1243 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03410 Base excision repair [PATH:sch03410] D Sphch_1022 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D Sphch_2613 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D Sphch_2078 HhH-GPD family protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D Sphch_2916 Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D Sphch_1568 HhH-GPD family protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21] D Sphch_2269 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D Sphch_0617 Uracil-DNA glycosylase superfamily K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D Sphch_2436 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D Sphch_0790 uracil-DNA glycosylase superfamily K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D Sphch_1520 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D Sphch_2210 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D Sphch_1681 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Sphch_1782 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Sphch_1243 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03420 Nucleotide excision repair [PATH:sch03420] D Sphch_0521 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D Sphch_0138 UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A D Sphch_1753 UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B D Sphch_0350 UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C D Sphch_0654 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Sphch_1930 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Sphch_1681 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Sphch_1243 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03430 Mismatch repair [PATH:sch03430] D Sphch_2206 DNA mismatch repair protein mutS K03555 mutS; DNA mismatch repair protein MutS D Sphch_0844 DNA mismatch repair protein mutL K03572 mutL; DNA mismatch repair protein MutL D Sphch_0654 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Sphch_1930 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Sphch_2084 Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D Sphch_1309 Exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D Sphch_1782 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Sphch_2301 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Sphch_4134 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Sphch_4121 single-strand binding protein/Primosomal replication protein n K03111 ssb; single-strand DNA-binding protein D Sphch_0794 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Sphch_1759 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Sphch_0635 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Sphch_2244 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Sphch_0716 DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Sphch_2228 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Sphch_1580 DNA polymerase III chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] D Sphch_1243 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03440 Homologous recombination [PATH:sch03440] D Sphch_1782 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Sphch_2301 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Sphch_4134 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Sphch_4121 single-strand binding protein/Primosomal replication protein n K03111 ssb; single-strand DNA-binding protein D Sphch_1773 DNA replication and repair protein recF K03629 recF; DNA replication and repair protein RecF D Sphch_0370 DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O) D Sphch_1544 Recombination protein recR K06187 recR; recombination protein RecR D Sphch_1785 Protein recA K03553 recA; recombination protein RecA D Sphch_1681 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Sphch_2066 Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA D Sphch_2065 Holliday junction ATP-dependent DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D Sphch_2862 Crossover junction endodeoxyribonuclease ruvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D Sphch_0523 DEAD/DEAH box helicase domain protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D Sphch_0794 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Sphch_1759 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Sphch_0635 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Sphch_2244 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Sphch_0716 DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Sphch_2228 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Sphch_1580 DNA polymerase III chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] D Sphch_0074 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] C 03450 Non-homologous end-joining [PATH:sch03450] D Sphch_3000 DNA repair protein K10979 ku; DNA end-binding protein Ku D Sphch_2999 DNA ligase D K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 [PATH:sch03250] D Sphch_0002 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D Sphch_3983 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D Sphch_1781 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus and Lyssavirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:sch02010] D Sphch_0688 ABC-type nitrate/sulfonate/bicarbonate transport system periplasmic component K15576 nrtA; nitrate/nitrite transport system substrate-binding protein D Sphch_0689 nitrate ABC transporter, inner membrane subunit K15577 nrtB; nitrate/nitrite transport system permease protein D Sphch_0690 nitrate ABC transporter, ATPase subunits C and D K15578 nrtC; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4] D Sphch_3736 aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein D Sphch_3548 aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein D Sphch_3539 ABC-type transporter, periplasmic subunit family 3 K15553 ssuA; sulfonate transport system substrate-binding protein D Sphch_3543 ABC-type transporter, integral membrane subunit K15554 ssuC; sulfonate transport system permease protein D Sphch_3544 Polyamine-transporting ATPase K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D Sphch_1667 molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 modA; molybdate transport system substrate-binding protein D Sphch_1669 molybdate ABC transporter, inner membrane subunit K02018 modB; molybdate transport system permease protein D Sphch_1670 Molybdate-transporting ATPase K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D Sphch_2261 Mammalian cell entry related domain protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein D Sphch_2263 protein of unknown function DUF140 K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein D Sphch_2262 Fe(3+)-transporting ATPase K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein D Sphch_1537 phosphate transport system substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D Sphch_1538 phosphate ABC transporter, inner membrane subunit PstC K02037 pstC; phosphate transport system permease protein D Sphch_1539 phosphate ABC transporter, inner membrane subunit PstA K02038 pstA; phosphate transport system permease protein D Sphch_1540 phosphate ABC transporter, ATPase subunit K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Sphch_2701 capsule polysaccharide export-like protein K10107 kpsE; capsular polysaccharide transport system permease protein D Sphch_2700 ABC-2 type transporter K09688 kpsM; capsular polysaccharide transport system permease protein D Sphch_2688 Capsular-polysaccharide-transporting ATPase K09689 kpsT; capsular polysaccharide transport system ATP-binding protein [EC:7.6.2.12] D Sphch_0797 lipoprotein releasing system, transmembrane protein, LolC/E family K09808 lolC_E; lipoprotein-releasing system permease protein D Sphch_0796 Phosphonate-transporting ATPase K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] D Sphch_0806 heme exporter protein CcmC K02195 ccmC; heme exporter protein C D Sphch_0084 cytochrome c-type biogenesis protein CcmB K02194 ccmB; heme exporter protein B D Sphch_0085 heme exporter protein CcmA K02193 ccmA; heme exporter protein A [EC:7.6.2.5] D Sphch_1514 permease YjgP/YjgQ family protein K07091 lptF; lipopolysaccharide export system permease protein D Sphch_1515 permease YjgP/YjgQ family protein K11720 lptG; lipopolysaccharide export system permease protein D Sphch_1916 Sulfate-transporting ATPase K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5] D Sphch_2353 protein of unknown function DUF214 K09811 ftsX; cell division transport system permease protein D Sphch_2354 cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein D Sphch_1972 Xenobiotic-transporting ATPase K24821 atm1; ATP-binding cassette, subfamily B, heavy metal transporter D Sphch_0379 type I secretion system ATPase K12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB D Sphch_3024 Peptide-transporting ATPase K12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB D Sphch_0818 type I secretion system ATPase K12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase C 02060 Phosphotransferase system (PTS) [PATH:sch02060] D Sphch_1628 Phosphotransferase system, phosphocarrier protein HPr K02784 ptsH; phosphocarrier protein HPr D Sphch_1627 PTS system fructose subfamily IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D Sphch_1602 PTSINtr with GAF domain, PtsP K08484 ptsP; phosphotransferase system, enzyme I, PtsP [EC:2.7.3.9] D Sphch_2230 putative PTS IIA-like nitrogen-regulatory protein PtsN K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-] C 03070 Bacterial secretion system [PATH:sch03070] D Sphch_1575 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein D Sphch_1280 general secretion pathway protein D K02453 gspD; general secretion pathway protein D D Sphch_1281 type II secretory pathway component PulC K02452 gspC; general secretion pathway protein C D Sphch_1278 general secretion pathway protein F K02455 gspF; general secretion pathway protein F D Sphch_1277 general secretion pathway protein G K02456 gspG; general secretion pathway protein G D Sphch_1276 general secretion pathway protein H K02457 gspH; general secretion pathway protein H D Sphch_1275 general secretion pathway protein I K02458 gspI; general secretion pathway protein I D Sphch_1274 general secretion pathway protein J K02459 gspJ; general secretion pathway protein J D Sphch_1273 type II secretory pathway component PulK K02460 gspK; general secretion pathway protein K D Sphch_1272 General secretion pathway L K02461 gspL; general secretion pathway protein L D Sphch_1271 General secretion pathway M protein K02462 gspM; general secretion pathway protein M D Sphch_1279 general secretory pathway protein E K02454 gspE; general secretion pathway protein E [EC:7.4.2.8] D Sphch_1842 protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD D Sphch_1841 protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF D Sphch_2984 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Sphch_1260 preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Sphch_1809 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Sphch_1843 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Sphch_2908 Membrane protein oxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase D Sphch_0723 Protein translocase subunit secA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Sphch_1644 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Sphch_0006 Protein-export protein secB K03071 secB; preprotein translocase subunit SecB D Sphch_1639 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Sphch_1440 Sec-independent protein translocase protein tatA/E-like protein K03116 tatA; sec-independent protein translocase protein TatA D Sphch_1439 twin-arginine translocation protein, TatB subunit K03117 tatB; sec-independent protein translocase protein TatB D Sphch_1438 Sec-independent protein translocase, TatC subunit K03118 tatC; sec-independent protein translocase protein TatC D Sphch_4164 Lytic transglycosylase catalytic K03194 virB1; type IV secretion system protein VirB1 D Sphch_1489 Conjugal transfer protein TrbC K03197 virB2; type IV secretion system protein VirB2 D Sphch_4163 Conjugal transfer protein TrbC K03197 virB2; type IV secretion system protein VirB2 D Sphch_1488 type IV secretory pathway VirB3 family protein K03198 virB3; type IV secretion system protein VirB3 D Sphch_4162 type IV secretory pathway VirB3 family protein K03198 virB3; type IV secretion system protein VirB3 D Sphch_4160 type IV secretion system family protein K03200 virB5; type IV secretion system protein VirB5 D Sphch_1484 Conjugal transfer protein TrbG/VirB9/CagX K03204 virB9; type IV secretion system protein VirB9 D Sphch_4157 P-type conjugative transfer protein VirB9 K03204 virB9; type IV secretion system protein VirB9 D Sphch_4159 TrbL/VirB6 plasmid conjugal transfer protein K03201 virB6; type IV secretion system protein VirB6 D Sphch_1485 VirB8 family protein K03203 virB8; type IV secretion system protein VirB8 D Sphch_4158 VirB8 family protein K03203 virB8; type IV secretion system protein VirB8 D Sphch_1483 conjugation TrbI family protein K03195 virB10; type IV secretion system protein VirB10 D Sphch_4156 conjugation TrbI family protein K03195 virB10; type IV secretion system protein VirB10 D Sphch_1487 type IV secretion/conjugal transfer ATPase, VirB4 family K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8] D Sphch_4161 type IV secretion/conjugal transfer ATPase, VirB4 family K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8] D Sphch_1482 P-type DNA transfer ATPase VirB11 K03196 virB11; type IV secretion system protein VirB11 [EC:7.4.2.8] D Sphch_4155 P-type DNA transfer ATPase VirB11 K03196 virB11; type IV secretion system protein VirB11 [EC:7.4.2.8] D Sphch_2733 TRAG family protein K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8] D Sphch_4154 TRAG family protein K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8] B B 09132 Signal transduction C 02020 Two-component system [PATH:sch02020] D Sphch_1536 histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D Sphch_1542 two component transcriptional regulator PhoB, winged helix family K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB D Sphch_1537 phosphate transport system substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D Sphch_1752 Acid phosphatase K09474 phoN; acid phosphatase (class A) [EC:3.1.3.2] D Sphch_3129 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Sphch_1769 putative protease K04771 degP; serine protease Do [EC:3.4.21.107] D Sphch_4090 copper efflux system periplasmic protein CusF K07810 cusF; Cu(I)/Ag(I) efflux system periplasmic protein CusF D Sphch_4088 efflux transporter, RND family, MFP subunit K07798 cusB; membrane fusion protein, copper/silver efflux system D Sphch_4089 heavy metal efflux pump, CzcA family K07787 cusA; copper/silver efflux system protein D Sphch_2642 flagellin domain protein K02406 fliC; flagellin D Sphch_2639 RNA polymerase, sigma 28 subunit, FliA/WhiG K02405 fliA; RNA polymerase sigma factor FliA D Sphch_2620 flagellar motor stator protein MotA K02556 motA; chemotaxis protein MotA D Sphch_2632 MotA/TolQ/ExbB proton channel K02556 motA; chemotaxis protein MotA D Sphch_1027 osmosensitive K+ channel signal transduction histidine kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3] D Sphch_1028 two component transcriptional regulator, winged helix family K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE D Sphch_1024 Potassium-transporting ATPase A chain K01546 kdpA; potassium-transporting ATPase potassium-binding subunit D Sphch_1025 Potassium-transporting ATPase B chain K01547 kdpB; potassium-transporting ATPase ATP-binding subunit [EC:7.2.2.6] D Sphch_1026 Potassium-transporting ATPase C chain K01548 kdpC; potassium-transporting ATPase KdpC subunit D Sphch_0080 Heme A synthase K02259 COX15; heme a synthase [EC:1.17.99.9] D Sphch_2587 Levansucrase K00692 sacB; levansucrase [EC:2.4.1.10] D Sphch_0001 Chromosomal replication initiator protein dnaA K02313 dnaA; chromosomal replication initiator protein D Sphch_2482 hypothetical protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3] D Sphch_1624 integral membrane sensor signal transduction histidine kinase K14980 chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3] D Sphch_1623 two component transcriptional regulator, winged helix family K14981 chvI; two-component system, OmpR family, response regulator ChvI D Sphch_1298 Citryl-CoA lyase K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34] D Sphch_2143 Citryl-CoA lyase K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34] D Sphch_0141 two component transcriptional regulator, LytTR family K08083 algR; two-component system, LytTR family, response regulator AlgR D Sphch_2191 two component transcriptional regulator, LuxR family K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL D Sphch_0353 Flp pilus assembly protein pilin Flp K02651 flp; pilus assembly protein Flp/PilA D Sphch_0354 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA D Sphch_1318 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA D Sphch_1319 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA D Sphch_3206 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA D Sphch_0355 Flp pilus assembly protein CpaB K02279 cpaB; pilus assembly protein CpaB D Sphch_1366 Flp pilus assembly protein CpaB K02279 cpaB; pilus assembly protein CpaB D Sphch_3214 Flp pilus assembly protein CpaB K02279 cpaB; pilus assembly protein CpaB D Sphch_0356 type II and III secretion system protein K02280 cpaC; pilus assembly protein CpaC D Sphch_1367 type II and III secretion system protein K02280 cpaC; pilus assembly protein CpaC D Sphch_3213 type II and III secretion system protein K02280 cpaC; pilus assembly protein CpaC D Sphch_0361 Flp pilus assembly protein ATPase CpaE K02282 cpaE; pilus assembly protein CpaE D Sphch_1369 Flp pilus assembly protein ATPase CpaE K02282 cpaE; pilus assembly protein CpaE D Sphch_3212 response regulator receiver protein K02282 cpaE; pilus assembly protein CpaE D Sphch_0064 type II secretion system protein E K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] D Sphch_0362 type II secretion system protein E K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] D Sphch_3211 type II secretion system protein E K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] D Sphch_0363 Type II secretion system F domain protein K12510 tadB; tight adherence protein B D Sphch_1370 Type II secretion system F domain protein K12510 tadB; tight adherence protein B D Sphch_3210 Type II secretion system F domain protein K12510 tadB; tight adherence protein B D Sphch_0364 Type II secretion system F domain protein K12511 tadC; tight adherence protein C D Sphch_1371 Type II secretion system F domain protein K12511 tadC; tight adherence protein C D Sphch_3209 Type II secretion system F domain protein K12511 tadC; tight adherence protein C D Sphch_3207 Protein of unknown function DUF2134, membrane K27080 tadG; tight adherence protein G D Sphch_2207 UTP-GlnB uridylyltransferase, GlnD K00990 glnD; [protein-PII] uridylyltransferase [EC:2.7.7.59] D Sphch_1003 nitrogen regulatory protein P-II K04751 glnB; nitrogen regulatory protein P-II 1 D Sphch_0703 signal transduction histidine kinase, nitrogen specific, NtrB K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3] D Sphch_0704 nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG D Sphch_1004 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Sphch_0705 multi-sensor signal transduction histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] D Sphch_0706 two component, sigma54 specific, transcriptional regulator, Fis family K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX D Sphch_0612 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0180 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0094 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0995 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3248 acetyl-coenzyme A synthetase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_1080 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3982 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0756 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3830 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3834 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3054 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3883 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3885 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3931 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3997 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3506 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3670 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3497 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3386 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_2785 C4-dicarboxylate transport protein K11103 dctA; aerobic C4-dicarboxylate transport protein D Sphch_1917 RNA polymerase, sigma 54 subunit, RpoN K03092 rpoN; RNA polymerase sigma-54 factor D Sphch_1652 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Sphch_1699 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Sphch_0531 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Sphch_0188 methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor K03406 mcp; methyl-accepting chemotaxis protein D Sphch_3174 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Sphch_1655 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW D Sphch_1656 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Sphch_1654 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Sphch_1653 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Sphch_2281 response regulator receiver protein K11443 divK; two-component system, cell cycle response regulator DivK D Sphch_1787 multi-sensor hybrid histidine kinase K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3] D Sphch_1006 Protein of unknown function DUF2328 K13588 chpT; histidine phosphotransferase ChpT D Sphch_0261 two component transcriptional regulator, winged helix family K13584 ctrA; two-component system, cell cycle response regulator CtrA D Sphch_2786 response regulator receiver protein K13589 cpdR; two-component system, cell cycle response regulator CpdR D Sphch_0894 multi-sensor signal transduction histidine kinase K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3] D Sphch_4187 PAS/PAC sensor signal transduction histidine kinase K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3] D Sphch_3367 PAS/PAC sensor signal transduction histidine kinase K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3] D Sphch_0893 two component transcriptional regulator, LuxR family K14987 fixJ; two-component system, LuxR family, response regulator FixJ D Sphch_4188 two component transcriptional regulator, LuxR family K14987 fixJ; two-component system, LuxR family, response regulator FixJ D Sphch_3366 two component transcriptional regulator, LuxR family K14987 fixJ; two-component system, LuxR family, response regulator FixJ D Sphch_4176 two component transcriptional regulator, LuxR family K14987 fixJ; two-component system, LuxR family, response regulator FixJ D Sphch_2643 sigma54 specific transcriptional regulator, Fis family K10943 flrC; two-component system, response regulator FlrC D Sphch_1166 Enoyl-CoA hydratase/isomerase K13816 rpfF; DSF synthase D Sphch_0646 Glutaminase K01425 glsA; glutaminase [EC:3.5.1.2] D Sphch_1105 integral membrane sensor signal transduction histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3] D Sphch_1106 two component transcriptional regulator, Fis family K15012 regA; two-component system, response regulator RegA D Sphch_2675 ubiquinol-cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8] D Sphch_2676 Cytochrome b/b6 domain protein K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit D Sphch_2677 cytochrome c1 K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit D Sphch_0109 cytochrome c class I K08738 CYC; cytochrome c D Sphch_0996 cytochrome c class I K08738 CYC; cytochrome c D Sphch_2835 cytochrome c class I K08738 CYC; cytochrome c D Sphch_3401 cytochrome c oxidase, cbb3-type, subunit I K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9] D Sphch_3402 cytochrome c oxidase, cbb3-type, subunit II K00405 ccoO; cytochrome c oxidase cbb3-type subunit II D Sphch_3403 Cbb3-type cytochrome oxidase subunit 3 K00407 ccoQ; cytochrome c oxidase cbb3-type subunit IV D Sphch_3404 cytochrome c oxidase, cbb3-type, subunit III K00406 ccoP; cytochrome c oxidase cbb3-type subunit III D Sphch_1575 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein D Sphch_0481 polysaccharide export protein K01991 wza; polysaccharide biosynthesis/export protein D Sphch_0392 polysaccharide export protein K01991 wza; polysaccharide biosynthesis/export protein D Sphch_1238 polysaccharide export protein K01991 wza; polysaccharide biosynthesis/export protein D Sphch_0968 polysaccharide export protein K01991 wza; polysaccharide biosynthesis/export protein D Sphch_2183 polysaccharide export protein K01991 wza; polysaccharide biosynthesis/export protein D Sphch_2696 polysaccharide export protein K01991 wza; polysaccharide biosynthesis/export protein D Sphch_2428 protein tyrosine phosphatase K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48] D Sphch_0390 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D Sphch_0391 nucleotide sugar dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336] D Sphch_3100 Pectinesterase K01051 E3.1.1.11; pectinesterase [EC:3.1.1.11] D Sphch_0581 anti-FecI sigma factor, FecR K07165 fecR; transmembrane sensor D Sphch_2153 anti-FecI sigma factor, FecR K07165 fecR; transmembrane sensor D Sphch_1019 anti-FecI sigma factor, FecR K07165 fecR; transmembrane sensor D Sphch_2712 anti-FecI sigma factor, FecR K07165 fecR; transmembrane sensor D Sphch_3948 anti-FecI sigma factor, FecR K07165 fecR; transmembrane sensor D Sphch_3519 Hpt domain protein K20976 hptB; histidine phosphotransfer protein HptB D Sphch_0053 Hpt domain protein K20976 hptB; histidine phosphotransfer protein HptB D Sphch_2635 flagellar biosynthesis anti-sigma factor protein FlgM K02398 flgM; negative regulator of flagellin synthesis FlgM C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis [PATH:sch04148] D Sphch_0782 Ornithine decarboxylase K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17] D Sphch_2675 ubiquinol-cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8] B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:sch02024] D Sphch_0707 Protein hfq K03666 hfq; host factor-I protein D Sphch_1263 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Sphch_1737 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D Sphch_1688 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D Sphch_1028 two component transcriptional regulator, winged helix family K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE D Sphch_2735 P-type conjugative transfer ATPase TrbB K20527 trbB; type IV secretion system protein TrbB [EC:7.4.2.8] D Sphch_2518 hypothetical protein K20528 trbC; type IV secretion system protein TrbC D Sphch_2736 Conjugal transfer protein TrbC K20528 trbC; type IV secretion system protein TrbC D Sphch_2737 putative conjugal transfer TrbD transmembrane protein K20529 trbD; type IV secretion system protein TrbD D Sphch_2738 CagE, TrbE, VirB component of type IV transporter system, conserved region K20530 trbE; type IV secretion system protein TrbE [EC:7.4.2.8] D Sphch_2739 P-type conjugative transfer protein TrbJ K20266 trbJ; type IV secretion system protein TrbJ D Sphch_2740 P-type conjugative transfer protein TrbL K07344 trbL; type IV secretion system protein TrbL D Sphch_2741 conjugal transfer protein TrbF K20531 trbF; type IV secretion system protein TrbF D Sphch_2742 P-type conjugative transfer protein TrbG K20532 trbG; type IV secretion system protein TrbG D Sphch_2743 conjugation TrbI family protein K20533 trbI; type IV secretion system protein TrbI D Sphch_2198 putative pectate lyase K01728 pel; pectate lyase [EC:4.2.2.2] D Sphch_4168 Autoinducer-binding domain protein K19731 cciR; LuxR family transcriptional regulator, quorum-sensing system regulator CciR D Sphch_1166 Enoyl-CoA hydratase/isomerase K13816 rpfF; DSF synthase D Sphch_0376 outer membrane adhesin like proteiin K20276 bapA; large repetitive protein D Sphch_0456 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0228 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_2064 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_2957 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3826 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3842 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3589 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0684 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3839 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0604 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_1122 Fur-family ferric uptake regulator K09823 zur; Fur family transcriptional regulator, zinc uptake regulator D Sphch_2209 GTP cyclohydrolase-2 K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] D Sphch_2371 riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D Sphch_3746 RND efflux system, outer membrane lipoprotein, NodT family K18139 oprM; outer membrane protein, multidrug efflux system D Sphch_1044 RND efflux system, outer membrane lipoprotein, NodT family K18139 oprM; outer membrane protein, multidrug efflux system D Sphch_2873 ABC-type transporter, periplasmic subunit K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Sphch_2908 Membrane protein oxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase D Sphch_2984 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Sphch_1260 preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Sphch_1809 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Sphch_1843 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Sphch_0723 Protein translocase subunit secA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Sphch_1644 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Sphch_0006 Protein-export protein secB K03071 secB; preprotein translocase subunit SecB D Sphch_1639 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis [PATH:sch02030] D Sphch_1699 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Sphch_0531 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Sphch_0188 methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor K03406 mcp; methyl-accepting chemotaxis protein D Sphch_3174 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Sphch_1656 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Sphch_1655 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW D Sphch_1654 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Sphch_1653 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Sphch_1652 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Sphch_2646 flagellar motor switch protein FliG K02410 fliG; flagellar motor switch protein FliG D Sphch_2652 surface presentation of antigens (SPOA) protein K02416 fliM; flagellar motor switch protein FliM D Sphch_2653 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Sphch_2620 flagellar motor stator protein MotA K02556 motA; chemotaxis protein MotA D Sphch_2632 MotA/TolQ/ExbB proton channel K02556 motA; chemotaxis protein MotA D Sphch_2619 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB C 02040 Flagellar assembly [PATH:sch02040] D Sphch_2644 Flagellar hook-basal body complex protein fliE K02408 fliE; flagellar hook-basal body complex protein FliE D Sphch_2645 flagellar M-ring protein FliF K02409 fliF; flagellar M-ring protein FliF D Sphch_2646 flagellar motor switch protein FliG K02410 fliG; flagellar motor switch protein FliG D Sphch_2647 flagellar biosynthetic protein FliH K02411 fliH; flagellar assembly protein FliH D Sphch_2648 ATPase, FliI/YscN family K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] D Sphch_2650 hypothetical protein K02414 fliK; flagellar hook-length control protein FliK D Sphch_2651 flagellar basal body-associated protein FliL K02415 fliL; flagellar protein FliL D Sphch_2652 surface presentation of antigens (SPOA) protein K02416 fliM; flagellar motor switch protein FliM D Sphch_2653 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Sphch_2654 flagellar biogenesis protein FliO K02418 fliO; flagellar protein FliO/FliZ D Sphch_2655 flagellar biosynthetic protein FliP K02419 fliP; flagellar biosynthesis protein FliP D Sphch_2656 flagellar biosynthetic protein FliQ K02420 fliQ; flagellar biosynthesis protein FliQ D Sphch_2657 flagellar biosynthetic protein FliR K02421 fliR; flagellar biosynthesis protein FliR D Sphch_2638 flagellar biosynthesis protein FlhA K02400 flhA; flagellar biosynthesis protein FlhA D Sphch_2658 type III secretion exporter K02401 flhB; flagellar biosynthesis protein FlhB D Sphch_2634 flagellar protein K02386 flgA; flagellar basal body P-ring formation protein FlgA D Sphch_2631 flagellar basal-body rod protein FlgB K02387 flgB; flagellar basal-body rod protein FlgB D Sphch_2630 flagellar basal-body rod protein FlgC K02388 flgC; flagellar basal-body rod protein FlgC D Sphch_2629 flagellar hook capping protein K02389 flgD; flagellar basal-body rod modification protein FlgD D Sphch_2628 flagellar hook-basal body protein K02390 flgE; flagellar hook protein FlgE D Sphch_2627 flagellar basal-body rod protein FlgF K02391 flgF; flagellar basal-body rod protein FlgF D Sphch_2626 flagellar basal-body rod protein FlgG K02392 flgG; flagellar basal-body rod protein FlgG D Sphch_2625 Flagellar L-ring protein K02393 flgH; flagellar L-ring protein FlgH D Sphch_2624 Flagellar P-ring protein K02394 flgI; flagellar P-ring protein FlgI D Sphch_2623 Flagellar protein FlgJ K02395 flgJ; peptidoglycan hydrolase FlgJ D Sphch_2622 flagellar hook-associated protein FlgK K02396 flgK; flagellar hook-associated protein 1 D Sphch_2621 flagellin domain protein K02397 flgL; flagellar hook-associated protein 3 FlgL D Sphch_2642 flagellin domain protein K02406 fliC; flagellin D Sphch_2660 flagellar hook-associated 2 domain-containing protein K02407 fliD; flagellar hook-associated protein 2 D Sphch_2661 flagellar protein FliS K02422 fliS; flagellar secretion chaperone FliS D Sphch_2620 flagellar motor stator protein MotA K02556 motA; chemotaxis protein MotA D Sphch_2632 MotA/TolQ/ExbB proton channel K02556 motA; chemotaxis protein MotA D Sphch_2619 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB D Sphch_2635 flagellar biosynthesis anti-sigma factor protein FlgM K02398 flgM; negative regulator of flagellin synthesis FlgM D Sphch_0536 RNA polymerase, sigma 70 subunit, RpoD K03086 rpoD; RNA polymerase primary sigma factor D Sphch_1917 RNA polymerase, sigma 54 subunit, RpoN K03092 rpoN; RNA polymerase sigma-54 factor D Sphch_2643 sigma54 specific transcriptional regulator, Fis family K10943 flrC; two-component system, response regulator FlrC D Sphch_2639 RNA polymerase, sigma 28 subunit, FliA/WhiG K02405 fliA; RNA polymerase sigma factor FliA C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D Sphch_0551 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism [PATH:sch04980] D Sphch_0043 ATP/cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D Sphch_0762 methylmalonyl-CoA mutase, large subunit K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] D Sphch_2811 Methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Sphch_2812 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance [PATH:sch01501] D Sphch_0662 major facilitator superfamily MFS_1 K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG D Sphch_1443 Beta-N-acetylhexosaminidase K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] D Sphch_2852 peptidase M56 BlaR1 K02172 blaR1; bla regulator protein blaR1 D Sphch_2851 transcriptional repressor, CopY family K02171 blaI; BlaI family transcriptional regulator, penicillinase repressor D Sphch_2614 Beta-lactamase K17836 penP; beta-lactamase class A [EC:3.5.2.6] D Sphch_2813 Beta-lactamase K17836 penP; beta-lactamase class A [EC:3.5.2.6] D Sphch_0634 Beta-lactamase K17836 penP; beta-lactamase class A [EC:3.5.2.6] D Sphch_1379 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Sphch_1046 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Sphch_3748 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Sphch_3747 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family K18138 acrB; multidrug efflux pump D Sphch_1378 acriflavin resistance protein K18138 acrB; multidrug efflux pump D Sphch_1045 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family K18138 acrB; multidrug efflux pump D Sphch_3746 RND efflux system, outer membrane lipoprotein, NodT family K18139 oprM; outer membrane protein, multidrug efflux system D Sphch_1044 RND efflux system, outer membrane lipoprotein, NodT family K18139 oprM; outer membrane protein, multidrug efflux system D Sphch_1575 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein D Sphch_0029 Peptidoglycan glycosyltransferase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Sphch_1118 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Sphch_2246 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Sphch_0848 penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D Sphch_1429 Peptidoglycan glycosyltransferase K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] C 01502 Vancomycin resistance [PATH:sch01502] D Sphch_1419 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Sphch_0757 Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D Sphch_1427 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D Sphch_1426 Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D Sphch_1423 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:sch01503] D Sphch_0827 Cadherin K01406 prtC; serralysin [EC:3.4.24.40] D Sphch_0028 cell wall hydrolase/autolysin K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D Sphch_3129 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Sphch_1769 putative protease K04771 degP; serine protease Do [EC:3.4.21.107] D Sphch_0002 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D Sphch_3983 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D Sphch_1781 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D Sphch_1379 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Sphch_1046 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Sphch_3748 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Sphch_3747 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family K18138 acrB; multidrug efflux pump D Sphch_1378 acriflavin resistance protein K18138 acrB; multidrug efflux pump D Sphch_1045 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family K18138 acrB; multidrug efflux pump D Sphch_1575 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein D Sphch_2482 hypothetical protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3] B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:sch01000] C 01001 Protein kinases [BR:sch01001] D Sphch_2163 HipA N-terminal domain protein K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] D Sphch_2767 HipA domain protein K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] D Sphch_0393 capsular exopolysaccharide family K16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3] D Sphch_2194 lipopolysaccharide biosynthesis protein K16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3] D Sphch_0478 capsular exopolysaccharide family K16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3] D Sphch_1236 putative exopolysaccharide biosynthesis protein K00903 epsB; protein-tyrosine kinase [EC:2.7.10.3] D Sphch_0971 putative capsular polysaccharide biosynthesis protein K00903 epsB; protein-tyrosine kinase [EC:2.7.10.3] D Sphch_1536 histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D Sphch_1027 osmosensitive K+ channel signal transduction histidine kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3] D Sphch_1624 integral membrane sensor signal transduction histidine kinase K14980 chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3] D Sphch_0142 putative signal transduction histidine kinase K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3] D Sphch_0703 signal transduction histidine kinase, nitrogen specific, NtrB K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3] D Sphch_0705 multi-sensor signal transduction histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] D Sphch_1656 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Sphch_1787 multi-sensor hybrid histidine kinase K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3] D Sphch_0894 multi-sensor signal transduction histidine kinase K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3] D Sphch_4187 PAS/PAC sensor signal transduction histidine kinase K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3] D Sphch_3367 PAS/PAC sensor signal transduction histidine kinase K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3] D Sphch_1105 integral membrane sensor signal transduction histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3] D Sphch_1246 signal transduction histidine kinase K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3] D Sphch_1163 signal transduction histidine kinase K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3] D Sphch_3520 integral membrane sensor hybrid histidine kinase K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] C 01009 Protein phosphatases and associated proteins [BR:sch01009] D Sphch_0733 Adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D Sphch_0329 Chaperone protein htpG K04079 HSP90A; molecular chaperone HtpG D Sphch_0570 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] C 01002 Peptidases and inhibitors [BR:sch01002] D Sphch_1127 Lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] D Sphch_1269 Prepilin peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D Sphch_0367 peptidase A24A prepilin type IV K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43] D Sphch_1365 peptidase A24A prepilin type IV K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43] D Sphch_0489 glutamine amidotransferase class-I K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Sphch_1876 GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Sphch_0807 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D Sphch_1900 Glutamate synthase (ferredoxin) K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D Sphch_1344 Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Sphch_1229 exosortase 1 system-associated amidotransferase 1 K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D Sphch_2715 asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D Sphch_0300 ErfK/YbiS/YcfS/YnhG family protein K21470 ycbB; L,D-transpeptidase YcbB D Sphch_2259 aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] D Sphch_3535 Oligopeptidase A K01414 prlC; oligopeptidase A [EC:3.4.24.70] D Sphch_0827 Cadherin K01406 prtC; serralysin [EC:3.4.24.40] D Sphch_2390 Endothelin-converting enzyme 1 K07386 pepO; putative endopeptidase [EC:3.4.24.-] D Sphch_1049 peptidase M16 domain protein K07263 pqqL; zinc protease [EC:3.4.24.-] D Sphch_2090 peptidase M16 domain protein K07263 pqqL; zinc protease [EC:3.4.24.-] D Sphch_0239 peptidase M17 leucyl aminopeptidase domain protein K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D Sphch_1581 cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D Sphch_0333 Membrane dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] D Sphch_3790 peptidase M19 renal dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] D Sphch_3481 peptidase M19 renal dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] D Sphch_0813 peptidase dimerization domain protein K01295 cpg; glutamate carboxypeptidase [EC:3.4.17.11] D Sphch_0011 Succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D Sphch_3398 amidohydrolase K12941 abgB; aminobenzoyl-glutamate utilization protein B D Sphch_1189 Peptidase M23 K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-] D Sphch_1002 methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D Sphch_1471 peptidase M24 K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] D Sphch_1977 peptidase M24 K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] D Sphch_1597 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D Sphch_2055 protease htpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D Sphch_1331 membrane-associated zinc metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] D Sphch_2852 peptidase M56 BlaR1 K02172 blaR1; bla regulator protein blaR1 D Sphch_3129 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Sphch_1769 putative protease K04771 degP; serine protease Do [EC:3.4.21.107] D Sphch_1874 Prolyl oligopeptidase K01322 PREP; prolyl oligopeptidase [EC:3.4.21.26] D Sphch_0741 Dipeptidyl-peptidase IV K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5] D Sphch_1976 Oligopeptidase B K01354 ptrB; oligopeptidase B [EC:3.4.21.83] D Sphch_0718 Serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D Sphch_1014 ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D Sphch_0637 anti-sigma H sporulation factor, LonB K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] D Sphch_1745 SOS-response transcriptional repressor, LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D Sphch_0769 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D Sphch_2451 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D Sphch_1756 proline iminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5] D Sphch_3450 Soluble epoxide hydrolase K27108 ephA_B; epoxide hydrolase A/B [EC:3.3.2.-] D Sphch_1910 carboxyl-terminal protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] D Sphch_1134 signal peptide peptidase SppA, 67K type K04773 sppA; protease IV [EC:3.4.21.-] D Sphch_3428 cyanophycinase K13282 cphB; cyanophycinase [EC:3.4.15.6] D Sphch_0013 peptidase U61 LD-carboxypeptidase A K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13] D Sphch_0203 phage prohead protease, HK97 family K06904 GP4; Escherichia/Staphylococcus phage prohead protease D Sphch_0751 ATP-dependent protease hslV K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2] D Sphch_3427 Asparaginase K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5] D Sphch_3970 Gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Sphch_2035 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D Sphch_2080 peptidase U62 modulator of DNA gyrase K03592 pmbA; PmbA protein D Sphch_1937 peptidase U62 modulator of DNA gyrase K03568 tldD; TldD protein D Sphch_3128 band 7 protein K04087 hflC; modulator of FtsH protease HflC D Sphch_3127 HflK protein K04088 hflK; modulator of FtsH protease HflK C 01003 Glycosyltransferases [BR:sch01003] D Sphch_0419 glycosyl transferase group 1 K12583 mgtA; phosphatidylinositol alpha 1,6-mannosyltransferase [EC:2.4.1.-] D Sphch_2897 glycosyl transferase group 1 K16150 K16150; glycogen synthase [EC:2.4.1.11] D Sphch_0587 Glycogen synthase K00703 glgA; starch synthase [EC:2.4.1.21] D Sphch_1011 monofunctional biosynthetic peptidoglycan transglycosylase K03814 mtgA; monofunctional glycosyltransferase [EC:2.4.99.28] D Sphch_0029 Peptidoglycan glycosyltransferase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Sphch_1118 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Sphch_2246 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Sphch_1231 sugar transferase, PEP-CTERM/EpsH1 system associated K21001 pslH; polysaccharide biosynthesis protein PslH D Sphch_0820 glycosyl transferase group 1 K21011 pelF; polysaccharide biosynthesis protein PelF D Sphch_0972 glycosyl transferase, WecB/TagA/CpsF family K05946 tagA; N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase [EC:2.4.1.187] D Sphch_2587 Levansucrase K00692 sacB; levansucrase [EC:2.4.1.10] D Sphch_2640 glycosyl transferase family 2 K03669 mdoH; membrane glycosyltransferase [EC:2.4.1.-] D Sphch_0899 carbohydrate binding protein K13688 chvB; cyclic beta-1,2-glucan glucanotransferase [EC:2.4.1.397] D Sphch_0398 alpha,alpha-trehalose-phosphate synthase (UDP-forming) K00697 otsA; trehalose 6-phosphate synthase [EC:2.4.1.15 2.4.1.347] D Sphch_0482 glycosyl transferase group 1 K16703 wcaL; colanic acid/amylovoran/stewartan biosynthesis glycosyltransferase WcaL/AmsK/CpsK [EC:2.4.-.-] C 01005 Lipopolysaccharide biosynthesis proteins [BR:sch01005] D Sphch_0669 lipid A biosynthesis acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-] D Sphch_2011 2-dehydro-3-deoxyphosphooctonate aldolase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55] D Sphch_2559 3-deoxy-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38] D Sphch_2558 KpsF/GutQ family protein K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13] C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:sch01011] D Sphch_1572 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D Sphch_1420 UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D Sphch_1422 UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D Sphch_1425 UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D Sphch_1428 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D Sphch_1419 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Sphch_0757 Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D Sphch_0776 Glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D Sphch_0013 peptidase U61 LD-carboxypeptidase A K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13] D Sphch_1426 Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D Sphch_1423 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D Sphch_1903 Undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D Sphch_0005 integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase D Sphch_0029 Peptidoglycan glycosyltransferase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Sphch_1118 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Sphch_2246 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Sphch_0848 penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D Sphch_1429 Peptidoglycan glycosyltransferase K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D Sphch_0718 Serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D Sphch_1011 monofunctional biosynthetic peptidoglycan transglycosylase K03814 mtgA; monofunctional glycosyltransferase [EC:2.4.99.28] D Sphch_0300 ErfK/YbiS/YcfS/YnhG family protein K21470 ycbB; L,D-transpeptidase YcbB D Sphch_1189 Peptidase M23 K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-] D Sphch_1791 Lytic transglycosylase catalytic K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29] D Sphch_0791 Lytic transglycosylase catalytic K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29] D Sphch_0008 MltA domain protein K08304 mltA; peptidoglycan lytic transglycosylase A [EC:4.2.2.29] D Sphch_0719 lytic murein transglycosylase K08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29] D Sphch_0325 aminodeoxychorismate lyase K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] D Sphch_0139 rare lipoprotein A K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29] D Sphch_0028 cell wall hydrolase/autolysin K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] C 01004 Lipid biosynthesis proteins [BR:sch01004] D Sphch_0320 malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D Sphch_2311 3-oxoacyl-(acyl-carrier-protein) synthase 3 K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D Sphch_0324 3-oxoacyl-(acyl-carrier-protein) synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D Sphch_0607 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_0322 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_3974 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_3566 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_3571 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Sphch_1328 (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D Sphch_1955 Enoyl-(acyl-carrier-protein) reductase (NADH) K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] D Sphch_1612 2-nitropropane dioxygenase NPD K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9] D Sphch_3409 lipolytic protein G-D-S-L family K10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5] D Sphch_3608 Choloyl-CoA hydrolase K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-] D Sphch_1065 thioesterase superfamily protein K10806 yciA; acyl-CoA thioesterase YciA [EC:3.1.2.-] D Sphch_2289 thioesterase superfamily protein K10806 yciA; acyl-CoA thioesterase YciA [EC:3.1.2.-] D Sphch_2018 Acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Sphch_3727 Acetyl-coenzyme A synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Sphch_3302 Propionate--CoA ligase K01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17] D Sphch_3998 acetoacetyl-CoA synthase K01907 AACS; acetoacetyl-CoA synthetase [EC:6.2.1.16] D Sphch_0456 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0228 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_2064 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_2957 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3826 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3842 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3589 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0684 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3839 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0604 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_1690 Long-chain-fatty-acid--(acyl-carrier-protein) ligase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] D Sphch_1850 Long-chain-fatty-acid--CoA ligase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] D Sphch_3851 Long-chain-fatty-acid--CoA ligase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] D Sphch_3062 Long-chain-fatty-acid--CoA ligase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] D Sphch_3902 o-succinylbenzoate--CoA ligase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] D Sphch_3929 o-succinylbenzoate--CoA ligase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] D Sphch_2538 Long-chain-fatty-acid--CoA ligase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] D Sphch_2590 Long-chain-fatty-acid--CoA ligase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] D Sphch_2310 Phosphate acyltransferase K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D Sphch_0775 Glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D Sphch_2351 phospholipid/glycerol acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 01008 Polyketide biosynthesis proteins [BR:sch01008] D Sphch_2794 aspartate racemase K01779 racD; aspartate racemase [EC:5.1.1.13] C 01006 Prenyltransferases [BR:sch01006] D Sphch_1308 Farnesyltranstransferase K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] D Sphch_1399 Trans-hexaprenyltranstransferase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90] D Sphch_1334 Undecaprenyl pyrophosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D Sphch_1941 Phytoene synthase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32] D Sphch_0569 tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D Sphch_2072 4-hydroxybenzoate polyprenyl transferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] D Sphch_2457 Protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] C 01007 Amino acid related enzymes [BR:sch01007] D Sphch_0021 lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Sphch_1747 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Sphch_2331 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Sphch_0045 Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain protein K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-] D Sphch_0526 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Sphch_0004 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Sphch_1686 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Sphch_1445 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Sphch_0715 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Sphch_1128 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Sphch_0048 Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Sphch_2242 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Sphch_1796 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Sphch_2284 Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Sphch_0832 Glycyl-tRNA synthetase alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D Sphch_0831 Glycyl-tRNA synthetase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D Sphch_0244 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Sphch_0753 Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Sphch_1591 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Sphch_0645 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Sphch_2340 Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Sphch_2341 Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Sphch_1556 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Sphch_1980 LL-diaminopimelate aminotransferase K14261 alaC; alanine-synthesizing transaminase [EC:2.6.1.-] D Sphch_1891 Kynurenine--oxoglutarate transaminase K14267 dapC; N-succinyldiaminopimelate aminotransferase [EC:2.6.1.17] D Sphch_2349 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_1603 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_1604 Histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Sphch_0777 5-aminolevulinic acid synthase K00643 E2.3.1.37; 5-aminolevulinate synthase [EC:2.3.1.37] D Sphch_1405 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D Sphch_2388 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D Sphch_2662 Acetylornithine/succinyldiaminopimelate aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Sphch_0449 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48] D Sphch_2392 Adenosylmethionine--8-amino-7-oxononanoate transaminase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62] D Sphch_1918 D-amino-acid transaminase K00824 dat; D-alanine transaminase [EC:2.6.1.21] D Sphch_2020 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Sphch_1967 phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] C 00199 Cytochrome P450 [BR:sch00199] D Sphch_3292 cytochrome P450 K22553 CYP199A2; 4-methoxybenzoate monooxygenase (O-demethylating) [EC:1.14.99.15] C 00194 Photosynthesis proteins [BR:sch00194] D Sphch_0065 ATPase, F1 complex, delta/epsilon subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D Sphch_0066 ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D Sphch_0067 ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D Sphch_0069 ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D Sphch_0070 ATP synthase subunit delta K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D Sphch_0348 H+transporting two-sector ATPase B/B' subunit K02109 ATPF0B; F-type H+-transporting ATPase subunit b D Sphch_0349 ATP synthase subunit b K02109 ATPF0B; F-type H+-transporting ATPase subunit b D Sphch_0347 H+transporting two-sector ATPase C subunit K02110 ATPF0C; F-type H+-transporting ATPase subunit c D Sphch_0346 ATP synthase subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a D Sphch_0345 ATP synthase protein I K02116 atpI; ATP synthase protein I B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:sch03000] D Sphch_1987 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Sphch_2001 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Sphch_2414 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Sphch_3923 transcriptional regulator, AraC family K18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA D Sphch_4044 transcriptional regulator, AraC family K07506 K07506; AraC family transcriptional regulator D Sphch_0072 Ada DNA repair protein and transcriptional regulator, AraC family K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63] D Sphch_0402 transcriptional regulator, LysR family K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator D Sphch_2015 transcriptional regulator, LysR family K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator D Sphch_0374 transcriptional regulator, LysR family K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator D Sphch_0461 transcriptional regulator, LysR family K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator D Sphch_1113 transcriptional regulator, LysR family K04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator D Sphch_4057 transcriptional regulator, LysR family K13634 cysB; LysR family transcriptional regulator, cys regulon transcriptional activator D Sphch_3894 transcriptional regulator, LysR family K16516 galR; LysR family transcriptional regulator, regulator for genes of the gallate degradation pathway D Sphch_2495 transcriptional regulator, LacI family K02529 galR; LacI family transcriptional regulator, galactose operon repressor D Sphch_1293 transcriptional regulator, LacI family K02529 galR; LacI family transcriptional regulator, galactose operon repressor D Sphch_3084 transcriptional regulator, LacI family K02529 galR; LacI family transcriptional regulator, galactose operon repressor D Sphch_3335 transcriptional regulator, LacI family K05499 cytR; LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG D Sphch_4070 transcriptional regulator, LacI family K06145 gntR; LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor D Sphch_3360 UbiC transcription regulator-associated domain-containing protein K05836 hutC; GntR family transcriptional regulator, histidine utilization repressor D Sphch_3293 transcriptional regulator, GntR family K11475 vanR; GntR family transcriptional regulator, vanillate catabolism transcriptional regulator D Sphch_3909 transcriptional regulator, GntR family K15735 csiR; GntR family transcriptional regulator, carbon starvation induced regulator D Sphch_0687 transcriptional regulator, GntR family K15735 csiR; GntR family transcriptional regulator, carbon starvation induced regulator D Sphch_1462 transcriptional regulator, TetR family K02167 betI; TetR/AcrR family transcriptional regulator, transcriptional repressor of bet genes D Sphch_2530 regulatory protein TetR K09017 rutR; TetR/AcrR family transcriptional regulator D Sphch_4006 regulatory protein TetR K09017 rutR; TetR/AcrR family transcriptional regulator D Sphch_2777 regulatory protein TetR K09017 rutR; TetR/AcrR family transcriptional regulator D Sphch_3686 regulatory protein TetR K09017 rutR; TetR/AcrR family transcriptional regulator D Sphch_3604 regulatory protein TetR K19736 aefR; TetR/AcrR family transcriptional regulator, regulator of autoinduction and epiphytic fitness D Sphch_1087 regulatory protein TetR K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon D Sphch_3859 regulatory protein TetR K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon D Sphch_4037 regulatory protein TetR K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon D Sphch_3449 regulatory protein TetR K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon D Sphch_3569 regulatory protein TetR K18301 mexL; TetR/AcrR family transcriptional regulator, mexJK operon transcriptional repressor D Sphch_3058 regulatory protein TetR K22108 kstR2; TetR/AcrR family transcriptional regulator, cholesterol catabolism regulator D Sphch_3724 regulatory protein TetR K22108 kstR2; TetR/AcrR family transcriptional regulator, cholesterol catabolism regulator D Sphch_3913 regulatory protein TetR K23777 cecR; TetR/AcrR family transcriptional regulator, regulator of cefoperazone and chloramphenicol sensitivity D Sphch_2539 regulatory protein TetR K23777 cecR; TetR/AcrR family transcriptional regulator, regulator of cefoperazone and chloramphenicol sensitivity D Sphch_0851 Transcriptional regulator TetR K23777 cecR; TetR/AcrR family transcriptional regulator, regulator of cefoperazone and chloramphenicol sensitivity D Sphch_3484 transcriptional regulator, AsnC family K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein D Sphch_3448 transcriptional regulator, AsnC family K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein D Sphch_1297 transcriptional regulator, AsnC family K05800 decR; Lrp/AsnC family transcriptional regulator, cysteine-sensing transcriptional activator D Sphch_0964 transcriptional regulator, AsnC family K05800 decR; Lrp/AsnC family transcriptional regulator, cysteine-sensing transcriptional activator D Sphch_3341 transcriptional regulator, AsnC family K05800 decR; Lrp/AsnC family transcriptional regulator, cysteine-sensing transcriptional activator D Sphch_4168 Autoinducer-binding domain protein K19731 cciR; LuxR family transcriptional regulator, quorum-sensing system regulator CciR D Sphch_2092 transcriptional regulator, MarR family K06075 slyA; MarR family transcriptional regulator, transcriptional regulator for hemolysin D Sphch_0384 transcriptional regulator, MarR family K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator D Sphch_4177 transcriptional regulator, MerR family K19591 cueR; MerR family transcriptional regulator, copper efflux regulator D Sphch_4083 transcriptional regulator, MerR family K19591 cueR; MerR family transcriptional regulator, copper efflux regulator D Sphch_1056 ferric uptake regulator, Fur family K03711 fur; Fur family transcriptional regulator, ferric uptake regulator D Sphch_1122 Fur-family ferric uptake regulator K09823 zur; Fur family transcriptional regulator, zinc uptake regulator D Sphch_3495 transcriptional regulator, IclR family K13641 iclR; IclR family transcriptional regulator, acetate operon repressor D Sphch_3492 transcriptional regulator, IclR family K02624 pcaR; IclR family transcriptional regulator, pca regulon regulatory protein D Sphch_3400 transcriptional regulator, Crp/Fnr family K01420 fnr; CRP/FNR family transcriptional regulator, anaerobic regulatory protein D Sphch_0047 transcriptional regulator, Crp/Fnr family K01420 fnr; CRP/FNR family transcriptional regulator, anaerobic regulatory protein D Sphch_0657 transcriptional regulator, BadM/Rrf2 family K13771 nsrR; Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor D Sphch_3963 regulatory protein ArsR K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor D Sphch_4126 regulatory protein ArsR K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor D Sphch_0765 transcriptional regulator, XRE family K21686 prpR; XRE family transcriptional regulator, fatty acid utilization regulator D Sphch_2567 transcriptional regulator, XRE family K07110 ramB; XRE family transcriptional regulator, fatty acid utilization regulator D Sphch_2842 transcriptional regulator, XRE family K07110 ramB; XRE family transcriptional regulator, fatty acid utilization regulator D Sphch_2851 transcriptional repressor, CopY family K02171 blaI; BlaI family transcriptional regulator, penicillinase repressor D Sphch_1172 biotin/acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D Sphch_0145 putative transcriptional regulator, ModE family K02019 modE; molybdate transport system regulatory protein D Sphch_3483 delta-1-pyrroline-5-carboxylate dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88] D Sphch_0906 CopG-like domain-containing protein DNA-binding protein K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB D Sphch_2357 BolA family protein K05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator D Sphch_2258 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_3193 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_3203 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_4142 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_4118 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_4124 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_2722 ParB domain protein nuclease K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_0959 PRTRC system ParB family protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_1459 transcriptional regulator, CarD family K07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription D Sphch_2858 heat-inducible transcription repressor HrcA K03705 hrcA; heat-inducible transcriptional repressor D Sphch_2044 sigma54 specific transcriptional activator, PspF, Fis family K03974 pspF; psp operon transcriptional activator D Sphch_2040 phage shock protein C K03973 pspC; phage shock protein C D Sphch_1779 PspC domain protein K03973 pspC; phage shock protein C D Sphch_0850 Prophage CP4-57 regulatory K07733 alpA; prophage regulatory protein D Sphch_2422 Prophage CP4-57 regulatory K07733 alpA; prophage regulatory protein D Sphch_2685 Prophage CP4-57 regulatory K07733 alpA; prophage regulatory protein D Sphch_0735 UPF0301 protein yqgE K07735 algH; putative transcriptional regulator D Sphch_0247 transcriptional regulator, TraR/DksA family K06204 dksA; RNA polymerase-binding transcription factor D Sphch_0897 TraR/DksA family transcriptional regulator K06204 dksA; RNA polymerase-binding transcription factor D Sphch_0625 Transcriptional repressor nrdR K07738 nrdR; transcriptional repressor NrdR D Sphch_1432 putative MraZ protein K03925 mraZ; transcriptional regulator MraZ C 03021 Transcription machinery [BR:sch03021] D Sphch_1872 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D Sphch_3135 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D Sphch_3136 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D Sphch_2480 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D Sphch_0536 RNA polymerase, sigma 70 subunit, RpoD K03086 rpoD; RNA polymerase primary sigma factor D Sphch_4183 RNA polymerase, sigma-24 subunit, ECF subfamily K24073 cnrH; RNA polymerase sigma factor CnrH D Sphch_1009 RNA polymerase, sigma 32 subunit, RpoH K03089 rpoH; RNA polymerase sigma-32 factor D Sphch_1917 RNA polymerase, sigma 54 subunit, RpoN K03092 rpoN; RNA polymerase sigma-54 factor D Sphch_2639 RNA polymerase, sigma 28 subunit, FliA/WhiG K02405 fliA; RNA polymerase sigma factor FliA D Sphch_1256 NusA antitermination factor K02600 nusA; transcription termination/antitermination protein NusA D Sphch_2384 NusB antitermination factor K03625 nusB; transcription antitermination protein NusB D Sphch_2985 NusG antitermination factor K02601 nusG; transcription termination/antitermination protein NusG D Sphch_0247 transcriptional regulator, TraR/DksA family K06204 dksA; RNA polymerase-binding transcription factor D Sphch_0897 TraR/DksA family transcriptional regulator K06204 dksA; RNA polymerase-binding transcription factor D Sphch_0544 transcription elongation factor GreA K03624 greA; transcription elongation factor GreA D Sphch_1792 transcription elongation factor GreB K04760 greB; transcription elongation factor GreB D Sphch_2248 transcription termination factor Rho K03628 rho; transcription termination factor Rho C 03019 Messenger RNA biogenesis [BR:sch03019] D Sphch_2014 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase D Sphch_0027 ribonuclease, Rne/Rng family K08300 rne; ribonuclease E [EC:3.1.26.12] D Sphch_0770 Ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3] D Sphch_1170 RNA-metabolising metallo-beta-lactamase K12574 rnj; ribonuclease J [EC:3.1.-.-] D Sphch_0421 ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] D Sphch_1050 DEAD/DEAH box helicase domain protein K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] D Sphch_2988 DEAD/DEAH box helicase domain protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Sphch_1950 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D Sphch_0551 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Sphch_1247 Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D Sphch_2248 transcription termination factor Rho K03628 rho; transcription termination factor Rho D Sphch_2944 Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK D Sphch_2487 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Sphch_0707 Protein hfq K03666 hfq; host factor-I protein D Sphch_2822 Polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] D Sphch_0405 Polynucleotide adenylyltransferase region K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] D Sphch_0811 RNA pyrophosphohydrolase K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-] D Sphch_1626 UPF0042 nucleotide-binding protein yhbJ K06958 rapZ; RNase adapter protein RapZ D Sphch_1401 ATP-dependent helicase HrpB K03579 hrpB; ATP-dependent RNA helicase HrpB [EC:5.6.2.6] C 03041 Spliceosome C 03011 Ribosome [BR:sch03011] D Sphch_0649 ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1 D Sphch_1338 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D Sphch_1823 ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D Sphch_0622 ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D Sphch_1812 ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D Sphch_0317 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D Sphch_1833 ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D Sphch_1815 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D Sphch_0082 ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D Sphch_1830 ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D Sphch_1871 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D Sphch_1834 ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D Sphch_1870 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D Sphch_1816 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D Sphch_1248 ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D Sphch_1638 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D Sphch_1820 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D Sphch_0316 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D Sphch_1825 ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D Sphch_2917 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D Sphch_2448 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D Sphch_2987 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D Sphch_1826 ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D Sphch_1829 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D Sphch_1828 ribosomal protein L4/L1e K02926 RP-L4; large subunit ribosomal protein L4 D Sphch_1817 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Sphch_1814 ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D Sphch_0315 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D Sphch_2796 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D Sphch_2986 ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Sphch_2795 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D Sphch_0081 ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D Sphch_1819 ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D Sphch_1810 ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D Sphch_1822 ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D Sphch_1873 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D Sphch_1813 ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D Sphch_1634 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D Sphch_2338 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D Sphch_2992 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D Sphch_1824 ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D Sphch_1827 Ribosomal protein L25/L23 K02892 RP-L23; large subunit ribosomal protein L23 D Sphch_1818 ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D Sphch_2993 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D Sphch_2805 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D Sphch_1821 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Sphch_1811 ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D Sphch_1327 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D Sphch_2309 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D Sphch_2367 ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D Sphch_2911 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D Sphch_2337 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D Sphch_2869 ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 D Sphch_0835 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25 D Sphch_R0047 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Sphch_R0062 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Sphch_R0063 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Sphch_R0043 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Sphch_R0058 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Sphch_R0067 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Sphch_R0046 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Sphch_R0061 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Sphch_R0064 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:sch03009] D Sphch_0770 Ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3] D Sphch_2014 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase D Sphch_0772 GTP-binding protein Era-like-protein K03595 era; GTPase D Sphch_2995 GTPase obg K03979 obgE; GTPase [EC:3.6.5.-] D Sphch_0247 transcriptional regulator, TraR/DksA family K06204 dksA; RNA polymerase-binding transcription factor D Sphch_0897 TraR/DksA family transcriptional regulator K06204 dksA; RNA polymerase-binding transcription factor D Sphch_1256 NusA antitermination factor K02600 nusA; transcription termination/antitermination protein NusA D Sphch_2384 NusB antitermination factor K03625 nusB; transcription antitermination protein NusB D Sphch_2985 NusG antitermination factor K02601 nusG; transcription termination/antitermination protein NusG D Sphch_1585 Ribosomal RNA small subunit methyltransferase A K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D Sphch_2275 Fmu (Sun) domain protein K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D Sphch_1588 Fmu (Sun) domain protein K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D Sphch_0659 methyltransferase K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171] D Sphch_2071 Ribosomal RNA small subunit methyltransferase E K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193] D Sphch_2256 Ribosomal RNA small subunit methyltransferase G K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D Sphch_1431 Ribosomal RNA small subunit methyltransferase H K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199] D Sphch_1710 Ribosomal RNA small subunit methyltransferase I K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198] D Sphch_1380 hemolysin A K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227] D Sphch_1565 RNA methyltransferase, TrmH family, group 3 K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185] D Sphch_1838 Ribosomal RNA large subunit methyltransferase E K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166] D Sphch_1912 Ribosomal RNA large subunit methyltransferase H K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177] D Sphch_2464 Protein of unknown function methylase putative K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191] D Sphch_3014 protein of unknown function DUF519 K07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266] D Sphch_1761 Ribosomal RNA large subunit methyltransferase N K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192] D Sphch_0783 (Uracil-5)-methyltransferase K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190] D Sphch_1213 pseudouridine synthase K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29] D Sphch_0660 pseudouridine synthase Rsu K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22] D Sphch_0294 pseudouridine synthase, RluA family K06179 rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24] D Sphch_1008 pseudouridine synthase, RluA family K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D Sphch_1549 pseudouridine synthase Rsu K06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20] D Sphch_1054 GCN5-related N-acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D Sphch_1637 Ribosome maturation factor rimM K02860 rimM; 16S rRNA processing protein RimM D Sphch_0242 Ribosomal protein S12 methylthiotransferase rimO K14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4] D Sphch_1700 ribosomal L11 methyltransferase K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-] D Sphch_1548 Cupin 4 family protein K18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47] D Sphch_0027 ribonuclease, Rne/Rng family K08300 rne; ribonuclease E [EC:3.1.26.12] D Sphch_0571 Holliday junction resolvase K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-] D Sphch_2988 DEAD/DEAH box helicase domain protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Sphch_0055 GTP-binding protein engA K03977 engA; GTPase D Sphch_0708 GTP-binding proten HflX K03665 hflX; GTPase D Sphch_0231 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Sphch_2797 (p)ppGpp synthetase I, SpoT/RelA K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D Sphch_1252 Ribosome-binding factor A K02834 rbfA; ribosome-binding factor A D Sphch_1257 Ribosome maturation factor rimP K09748 rimP; ribosome maturation factor RimP D Sphch_1913 iojap-like protein K09710 ybeB; ribosome-associated protein D Sphch_1060 metalloprotease ybeY K07042 ybeY; probable rRNA maturation factor D Sphch_2229 sigma 54 modulation protein/ribosomal protein S30EA K05808 hpf; ribosome hibernation promoting factor D Sphch_0839 GTP-binding protein YchF K06942 ychF; ribosome-binding ATPase C 03016 Transfer RNA biogenesis [BR:sch03016] D Sphch_1747 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Sphch_2331 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Sphch_0753 Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Sphch_1128 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Sphch_2242 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Sphch_0715 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Sphch_1445 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Sphch_1796 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Sphch_0645 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Sphch_1591 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Sphch_0244 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Sphch_1686 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Sphch_0048 Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Sphch_2284 Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Sphch_2340 Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Sphch_2341 Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Sphch_0526 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Sphch_0004 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Sphch_1675 histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D Sphch_0186 tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] D Sphch_1546 tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D Sphch_1249 tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D Sphch_0631 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Sphch_0632 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Sphch_0231 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Sphch_0569 tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D Sphch_2254 tRNA modification GTPase mnmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-] D Sphch_2255 tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D Sphch_3379 inositol monophosphatase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] D Sphch_2910 ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5] D Sphch_R0033 rnpB; RNA component of RNaseP K01978 rnpB; M1 RNA D Sphch_2856 Ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56] D Sphch_1797 ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5] D Sphch_2563 3'-5' exonuclease K03684 rnd; ribonuclease D [EC:3.1.13.5] D Sphch_0219 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58] D Sphch_2905 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58] D Sphch_0021 lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Sphch_0832 Glycyl-tRNA synthetase alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D Sphch_0831 Glycyl-tRNA synthetase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D Sphch_0045 Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain protein K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-] D Sphch_3505 YbaK/prolyl-tRNA synthetase associated region K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-] D Sphch_2803 CMP/dCMP deaminase zinc-binding protein K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33] D Sphch_0702 TIM-barrel protein, nifR3 family K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-] D Sphch_1058 (Dimethylallyl)adenosine tRNA methylthiotransferase miaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3] D Sphch_1643 MiaB-like tRNA modifying enzyme K18707 mtaB; threonylcarbamoyladenosine tRNA methylthiotransferase MtaB [EC:2.8.4.5] D Sphch_0624 tRNA/rRNA methyltransferase (SpoU) K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-] D Sphch_0560 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase trmFO K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D Sphch_1635 tRNA (guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D Sphch_2674 tRNA/rRNA methyltransferase (SpoU) K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207] D Sphch_1630 tRNA/rRNA methyltransferase (SpoU) K03437 spoU; RNA methyltransferase, TrmH family D Sphch_1213 pseudouridine synthase K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29] D Sphch_2381 tRNA-specific 2-thiouridylase mnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D Sphch_0054 putative redox protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D Sphch_2025 iron-sulfur cluster assembly accessory protein K13628 iscA; iron-sulfur cluster assembly protein D Sphch_0288 folate-binding protein YgfZ K06980 ygfZ; tRNA-modifying protein YgfZ D Sphch_1305 S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17] D Sphch_1926 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D Sphch_2666 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D Sphch_1925 6-pyruvoyl tetrahydropterin synthase and hypothetical protein K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D Sphch_2667 Radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D Sphch_2471 NADPH-dependent 7-cyano-7-deazaguanine reductase K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13] D Sphch_2320 domain of unknown function DUF1730 K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6] D Sphch_1164 Queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29] D Sphch_1599 tRNA(Ile)-lysidine synthase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19] D Sphch_1053 universal protein YeaZ K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB D Sphch_2326 O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234] D Sphch_0731 Uncharacterized protein family UPF0079, ATPase K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE D Sphch_0421 ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] D Sphch_1247 Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] C 03012 Translation factors [BR:sch03012] D Sphch_1253 translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D Sphch_1590 Translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D Sphch_1563 ABC transporter related protein K06158 ABCF3; ATP-binding cassette, subfamily F, member 3 D Sphch_1337 Elongation factor Ts K02357 tsf; elongation factor Ts D Sphch_1831 translation elongation factor Tu K02358 tuf; elongation factor Tu D Sphch_1832 translation elongation factor G K02355 fusA; elongation factor G D Sphch_3370 small GTP-binding protein K02355 fusA; elongation factor G D Sphch_2285 Peptide chain release factor 1 K02835 prfA; peptide chain release factor 1 D Sphch_1335 Ribosome-recycling factor K02838 frr; ribosome recycling factor D Sphch_2286 protein-(glutamine-N5) methyltransferase, release factor-specific K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D Sphch_0836 Peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D Sphch_2393 translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1 D Sphch_1188 Elongation factor P K02356 efp; elongation factor P D Sphch_0030 Peptide chain release factor 2 K02836 prfB; peptide chain release factor 2 D Sphch_2345 peptide chain release factor 3 K02837 prfC; peptide chain release factor 3 D Sphch_1214 Class I peptide chain release factor K15034 yaeJ; ribosome-associated protein C 03110 Chaperones and folding catalysts [BR:sch03110] D Sphch_0222 ATP-dependent Clp protease, ATP-binding subunit clpA K03694 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA D Sphch_2088 ATP-dependent chaperone ClpB K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB D Sphch_1013 ATP-dependent Clp protease ATP-binding subunit clpX K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX D Sphch_0752 heat shock protein HslVU, ATPase subunit HslU K03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU D Sphch_0329 Chaperone protein htpG K04079 HSP90A; molecular chaperone HtpG D Sphch_2944 Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK D Sphch_2487 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Sphch_2945 Chaperone protein dnaJ K03686 dnaJ; molecular chaperone DnaJ D Sphch_2664 Hsp33 protein K04083 hslO; molecular chaperone Hsp33 D Sphch_2859 Protein grpE K03687 GRPE; molecular chaperone GrpE D Sphch_0895 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein D Sphch_0798 heat shock protein Hsp20 K04080 ibpA; molecular chaperone IbpA D Sphch_1457 RNA-binding S4 domain protein K04762 hslR; ribosome-associated heat shock protein Hsp15 D Sphch_2488 10 kDa chaperonin K04078 groES; chaperonin GroES D Sphch_3129 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Sphch_1769 putative protease K04771 degP; serine protease Do [EC:3.4.21.107] D Sphch_1597 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D Sphch_0346 ATP synthase subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a D Sphch_0006 Protein-export protein secB K03071 secB; preprotein translocase subunit SecB D Sphch_2943 protein of unknown function DUF461 K09796 pccA; periplasmic copper chaperone A D Sphch_0002 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D Sphch_3983 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D Sphch_1781 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D Sphch_1262 peptidyl-prolyl cis-trans isomerase D K03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] D Sphch_2449 peptidylprolyl isomerase FKBP-type K03772 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8] D Sphch_1583 PpiC-type peptidyl-prolyl cis-trans isomerase K03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8] D Sphch_0726 thioredoxin K03671 TXN; thioredoxin D Sphch_2839 Thioredoxin domain-containing protein K05838 ybbN; putative thioredoxin D Sphch_1509 glutaredoxin 3 K03676 grxC; glutaredoxin 3 D Sphch_2850 glutaredoxin-like protein K07390 grxD; monothiol glutaredoxin D Sphch_0860 disulfide bond isomerase, DsbC/G K03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1] D Sphch_0802 Redoxin domain protein K02199 ccmG; cytochrome c biogenesis protein CcmG, thiol:disulfide interchange protein DsbE C 04131 Membrane trafficking [BR:sch04131] D Sphch_1579 Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Sphch_2014 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase D Sphch_2365 hypothetical protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family D Sphch_1905 protein of unknown function UPF0016 K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family D Sphch_1193 fructose-bisphosphate aldolase class-I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D Sphch_1195 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Sphch_1133 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D Sphch_2867 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Sphch_0329 Chaperone protein htpG K04079 HSP90A; molecular chaperone HtpG C 04121 Ubiquitin system [BR:sch04121] C 03051 Proteasome [BR:sch03051] D Sphch_0329 Chaperone protein htpG K04079 HSP90A; molecular chaperone HtpG C 03032 DNA replication proteins [BR:sch03032] D Sphch_1449 Ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D Sphch_1987 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Sphch_2001 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Sphch_2414 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Sphch_0638 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D Sphch_3198 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D Sphch_0015 Integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha D Sphch_0648 integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta D Sphch_0001 Chromosomal replication initiator protein dnaA K02313 dnaA; chromosomal replication initiator protein D Sphch_0273 replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D Sphch_0537 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D Sphch_2301 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Sphch_4134 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Sphch_4121 single-strand binding protein/Primosomal replication protein n K03111 ssb; single-strand DNA-binding protein D Sphch_0794 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Sphch_1759 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Sphch_1580 DNA polymerase III chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] D Sphch_2244 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Sphch_0716 DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Sphch_2228 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Sphch_0635 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Sphch_1466 Ribonuclease H K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Sphch_1681 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Sphch_1243 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Sphch_0673 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D Sphch_2270 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D Sphch_0403 DNA topoisomerase IV, A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D Sphch_0383 DNA topoisomerase IV, B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D Sphch_0773 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D Sphch_3003 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1] C 03036 Chromosome and associated proteins [BR:sch03036] D Sphch_1987 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Sphch_2001 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Sphch_2414 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Sphch_0770 Ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3] D Sphch_1193 fructose-bisphosphate aldolase class-I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D Sphch_4123 putative methylase/helicase K26273 SBNO; protein strawberry notch D Sphch_0638 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D Sphch_3198 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D Sphch_0015 Integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha D Sphch_0648 integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta D Sphch_0001 Chromosomal replication initiator protein dnaA K02313 dnaA; chromosomal replication initiator protein D Sphch_2476 hemimethylated DNA binding protein K11940 hspQ; heat shock protein HspQ D Sphch_2364 Ferritin Dps family protein K04047 dps; starvation-inducible DNA-binding protein D Sphch_0707 Protein hfq K03666 hfq; host factor-I protein D Sphch_3484 transcriptional regulator, AsnC family K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein D Sphch_3448 transcriptional regulator, AsnC family K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein D Sphch_2074 chromosome segregation protein SMC K03529 smc; chromosome segregation protein D Sphch_1442 chromosome segregation and condensation protein ScpA K05896 scpA; segregation and condensation protein A D Sphch_1441 chromosome segregation and condensation protein, ScpB K06024 scpB; segregation and condensation protein B D Sphch_1417 cell division protein FtsA K03590 ftsA; cell division protein FtsA D Sphch_2354 cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein D Sphch_1429 Peptidoglycan glycosyltransferase K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D Sphch_2212 cell division protein FtsK/SpoIIIE K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family D Sphch_1418 cell division protein FtsQ K03589 ftsQ; cell division protein FtsQ D Sphch_1424 cell cycle protein K03588 ftsW; cell division protein FtsW D Sphch_2353 protein of unknown function DUF214 K09811 ftsX; cell division transport system permease protein D Sphch_1416 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Sphch_1198 protein of unknown function DUF710 K09888 zapA; cell division protein ZapA D Sphch_1355 AFG1-family ATPase K06916 zapE; cell division protein ZapE D Sphch_0028 cell wall hydrolase/autolysin K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D Sphch_1379 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Sphch_1046 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Sphch_3748 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Sphch_0118 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins D Sphch_0845 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins D Sphch_0846 rod shape-determining protein MreC K03570 mreC; rod shape-determining protein MreC D Sphch_0847 hypothetical protein K03571 mreD; rod shape-determining protein MreD D Sphch_0849 rod shape-determining protein RodA K05837 rodA; rod shape determining protein RodA D Sphch_0431 ParA-like protein K03496 parA; chromosome partitioning protein D Sphch_2220 ATPase MipZ K03496 parA; chromosome partitioning protein D Sphch_2257 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Sphch_4141 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Sphch_4119 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Sphch_3192 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Sphch_1689 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Sphch_2258 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_3193 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_3203 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_4142 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_4118 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_4124 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_2722 ParB domain protein nuclease K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_0959 PRTRC system ParB family protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_0403 DNA topoisomerase IV, A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D Sphch_0383 DNA topoisomerase IV, B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D Sphch_2255 tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D Sphch_2256 Ribosomal RNA small subunit methyltransferase G K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D Sphch_0560 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase trmFO K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D Sphch_1706 Tyrosine recombinase xerC K03733 xerC; integrase/recombinase XerC D Sphch_2575 integrase family protein K03733 xerC; integrase/recombinase XerC D Sphch_1322 Tyrosine recombinase xerC K04763 xerD; integrase/recombinase XerD D Sphch_3126 ATPase-like, ParA/MinD K03593 mrp; ATP-binding protein involved in chromosome partitioning D Sphch_3162 filamentation induced by cAMP protein Fic K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108] D Sphch_2907 GTP-binding protein engB K03978 engB; GTP-binding protein C 03400 DNA repair and recombination proteins [BR:sch03400] D Sphch_1043 methylated-DNA/protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D Sphch_0810 DNA photolyase FAD-binding protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D Sphch_2613 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D Sphch_2078 HhH-GPD family protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D Sphch_1022 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D Sphch_1993 S1/P1 nuclease K05986 NUCS; nuclease S1 [EC:3.1.30.1] D Sphch_1317 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Sphch_1595 Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D Sphch_0072 Ada DNA repair protein and transcriptional regulator, AraC family K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63] D Sphch_0617 Uracil-DNA glycosylase superfamily K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D Sphch_2436 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D Sphch_0790 uracil-DNA glycosylase superfamily K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D Sphch_1568 HhH-GPD family protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21] D Sphch_2269 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D Sphch_2916 Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D Sphch_1520 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D Sphch_2210 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D Sphch_1782 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Sphch_1243 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Sphch_1681 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Sphch_0138 UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A D Sphch_1753 UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B D Sphch_0350 UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C D Sphch_0654 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Sphch_1930 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Sphch_3135 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D Sphch_3136 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D Sphch_1872 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D Sphch_2480 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D Sphch_0521 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D Sphch_2206 DNA mismatch repair protein mutS K03555 mutS; DNA mismatch repair protein MutS D Sphch_0844 DNA mismatch repair protein mutL K03572 mutL; DNA mismatch repair protein MutL D Sphch_2084 Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D Sphch_1309 Exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D Sphch_0794 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Sphch_1759 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Sphch_1580 DNA polymerase III chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] D Sphch_2244 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Sphch_0716 DNA polymerase III delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Sphch_2228 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Sphch_0635 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Sphch_2301 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Sphch_4134 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Sphch_4121 single-strand binding protein/Primosomal replication protein n K03111 ssb; single-strand DNA-binding protein D Sphch_1998 DNA mismatch endonuclease Vsr K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-] D Sphch_2411 DNA mismatch endonuclease Vsr K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-] D Sphch_1785 Protein recA K03553 recA; recombination protein RecA D Sphch_2066 Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA D Sphch_2065 Holliday junction ATP-dependent DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D Sphch_2862 Crossover junction endodeoxyribonuclease ruvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D Sphch_0074 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D Sphch_0091 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms D Sphch_1773 DNA replication and repair protein recF K03629 recF; DNA replication and repair protein RecF D Sphch_0523 DEAD/DEAH box helicase domain protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D Sphch_0370 DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O) D Sphch_1544 Recombination protein recR K06187 recR; recombination protein RecR D Sphch_1244 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) D Sphch_0727 double-strand break repair helicase AddA K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-] D Sphch_0728 double-strand break repair protein AddB K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-] D Sphch_3130 protein of unknown function DUF853 NPT hydrolase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase D Sphch_2415 DEAD/DEAH box helicase domain protein K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4] D Sphch_3000 DNA repair protein K10979 ku; DNA end-binding protein Ku D Sphch_2999 DNA ligase D K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] D Sphch_0673 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D Sphch_2270 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D Sphch_0773 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D Sphch_3003 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D Sphch_0638 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D Sphch_3198 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D Sphch_0015 Integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha D Sphch_0648 integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta D Sphch_1950 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] D Sphch_2172 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D Sphch_1745 SOS-response transcriptional repressor, LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D Sphch_0024 hypothetical protein K14160 imuA; protein ImuA D Sphch_0023 putative nucleotidyltransferase K14161 imuB; protein ImuB D Sphch_0022 Error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7] D Sphch_1691 regulatory protein RecX K03565 recX; regulatory protein D Sphch_0019 helicase c2 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D Sphch_2267 DEAD/H associated domain protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] D Sphch_3180 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Sphch_3182 Ribonucleoside-diphosphate reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C 03029 Mitochondrial biogenesis [BR:sch03029] D Sphch_2676 Cytochrome b/b6 domain protein K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit D Sphch_1253 translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D Sphch_1590 Translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D Sphch_1337 Elongation factor Ts K02357 tsf; elongation factor Ts D Sphch_1831 translation elongation factor Tu K02358 tuf; elongation factor Tu D Sphch_1832 translation elongation factor G K02355 fusA; elongation factor G D Sphch_3370 small GTP-binding protein K02355 fusA; elongation factor G D Sphch_2174 putative ubiquinol-cytochrome c chaperone K17662 CBP3; cytochrome b pre-mRNA-processing protein 3 D Sphch_1456 helicase domain-containing protein K17675 SUPV3L1; ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:5.6.2.6] D Sphch_0772 GTP-binding protein Era-like-protein K03595 era; GTPase D Sphch_0526 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Sphch_2242 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Sphch_1796 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Sphch_1445 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Sphch_0574 Glutamyl-tRNA(Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D Sphch_0575 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Sphch_0573 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D Sphch_2301 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Sphch_4134 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Sphch_4121 single-strand binding protein/Primosomal replication protein n K03111 ssb; single-strand DNA-binding protein D Sphch_1330 outer membrane protein assembly complex, YaeT protein K07277 SAM50; outer membrane protein insertion porin family D Sphch_2944 Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK D Sphch_2859 Protein grpE K03687 GRPE; molecular chaperone GrpE D Sphch_2487 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Sphch_2488 10 kDa chaperonin K04078 groES; chaperonin GroES D Sphch_2945 Chaperone protein dnaJ K03686 dnaJ; molecular chaperone DnaJ D Sphch_0631 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Sphch_0632 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Sphch_2850 glutaredoxin-like protein K07390 grxD; monothiol glutaredoxin D Sphch_1511 Methyltransferase type 11 K18162 NDUFAF5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 [EC:2.1.1.-] D Sphch_0313 protein of unknown function DUF185 K18164 NDUFAF7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7 D Sphch_3126 ATPase-like, ParA/MinD K03593 mrp; ATP-binding protein involved in chromosome partitioning D Sphch_2457 Protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D Sphch_2459 Cytochrome c oxidase assembly protein ctaG K02258 COX11; cytochrome c oxidase assembly protein subunit 11 D Sphch_0080 Heme A synthase K02259 COX15; heme a synthase [EC:1.17.99.9] D Sphch_2908 Membrane protein oxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase D Sphch_1104 Surfeit locus 1 family protein K14998 SURF1; surfeit locus 1 family protein D Sphch_2462 hypothetical protein K14998 SURF1; surfeit locus 1 family protein D Sphch_2441 electron transport protein SCO1/SenC K07152 SCO1; protein SCO1 D Sphch_0329 Chaperone protein htpG K04079 HSP90A; molecular chaperone HtpG B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:sch02000] D Sphch_1972 Xenobiotic-transporting ATPase K24821 atm1; ATP-binding cassette, subfamily B, heavy metal transporter D Sphch_2890 Xenobiotic-transporting ATPase K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial D Sphch_0379 type I secretion system ATPase K12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB D Sphch_3024 Peptide-transporting ATPase K12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB D Sphch_0818 type I secretion system ATPase K12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase D Sphch_1138 ABC transporter related protein K15738 uup; ABC transport system ATP-binding/permease protein D Sphch_1667 molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 modA; molybdate transport system substrate-binding protein D Sphch_1669 molybdate ABC transporter, inner membrane subunit K02018 modB; molybdate transport system permease protein D Sphch_1670 Molybdate-transporting ATPase K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D Sphch_0688 ABC-type nitrate/sulfonate/bicarbonate transport system periplasmic component K15576 nrtA; nitrate/nitrite transport system substrate-binding protein D Sphch_0689 nitrate ABC transporter, inner membrane subunit K15577 nrtB; nitrate/nitrite transport system permease protein D Sphch_0690 nitrate ABC transporter, ATPase subunits C and D K15578 nrtC; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4] D Sphch_3736 aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein D Sphch_3548 aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein D Sphch_3539 ABC-type transporter, periplasmic subunit family 3 K15553 ssuA; sulfonate transport system substrate-binding protein D Sphch_3543 ABC-type transporter, integral membrane subunit K15554 ssuC; sulfonate transport system permease protein D Sphch_3544 Polyamine-transporting ATPase K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D Sphch_2261 Mammalian cell entry related domain protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein D Sphch_2263 protein of unknown function DUF140 K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein D Sphch_2262 Fe(3+)-transporting ATPase K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein D Sphch_2260 protein of unknown function DUF330 K18480 linN; cholesterol transport system auxiliary component D Sphch_1537 phosphate transport system substrate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D Sphch_1538 phosphate ABC transporter, inner membrane subunit PstC K02037 pstC; phosphate transport system permease protein D Sphch_1539 phosphate ABC transporter, inner membrane subunit PstA K02038 pstA; phosphate transport system permease protein D Sphch_1540 phosphate ABC transporter, ATPase subunit K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Sphch_2873 ABC-type transporter, periplasmic subunit K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Sphch_1714 ABC-type transporter, periplasmic subunit K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D Sphch_1713 ABC-type transporter, integral membrane subunit K02015 ABC.FEV.P; iron complex transport system permease protein D Sphch_1712 Iron-chelate-transporting ATPase K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-] D Sphch_2700 ABC-2 type transporter K09688 kpsM; capsular polysaccharide transport system permease protein D Sphch_2701 capsule polysaccharide export-like protein K10107 kpsE; capsular polysaccharide transport system permease protein D Sphch_2688 Capsular-polysaccharide-transporting ATPase K09689 kpsT; capsular polysaccharide transport system ATP-binding protein [EC:7.6.2.12] D Sphch_1514 permease YjgP/YjgQ family protein K07091 lptF; lipopolysaccharide export system permease protein D Sphch_1515 permease YjgP/YjgQ family protein K11720 lptG; lipopolysaccharide export system permease protein D Sphch_1916 Sulfate-transporting ATPase K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5] D Sphch_0855 ABC-2 type transporter K25187 pltK; pyoluteorin transport system permease protein D Sphch_0854 ABC-2 type transporter K25188 pltJ; pyoluteorin transport system permease protein D Sphch_0853 Phosphonate-transporting ATPase., Sulfate-transporting ATPase K25189 pltI; pyoluteorin transport system ATP-binding protein D Sphch_0852 secretion protein HlyD family protein K25190 pltH; membrane fusion protein PltH D Sphch_0856 RND efflux system, outer membrane lipoprotein, NodT family K25184 pltN; outer membrane protein PltN D Sphch_0797 lipoprotein releasing system, transmembrane protein, LolC/E family K09808 lolC_E; lipoprotein-releasing system permease protein D Sphch_0796 Phosphonate-transporting ATPase K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] D Sphch_0806 heme exporter protein CcmC K02195 ccmC; heme exporter protein C D Sphch_0084 cytochrome c-type biogenesis protein CcmB K02194 ccmB; heme exporter protein B D Sphch_0085 heme exporter protein CcmA K02193 ccmA; heme exporter protein A [EC:7.6.2.5] D Sphch_2353 protein of unknown function DUF214 K09811 ftsX; cell division transport system permease protein D Sphch_2354 cell division ATP-binding protein FtsE K09812 ftsE; cell division transport system ATP-binding protein D Sphch_0151 putative ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein D Sphch_0150 putative ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein D Sphch_2318 ABC-type transport system permease component K01992 ABC-2.P; ABC-2 type transport system permease protein D Sphch_0387 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D Sphch_1068 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D Sphch_0152 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Sphch_2319 Sulfate-transporting ATPase K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Sphch_1069 Polyamine-transporting ATPase K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Sphch_2817 Sulfate-transporting ATPase K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Sphch_3411 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Sphch_3410 Phosphonate-transporting ATPase K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Sphch_2029 FeS assembly ATPase SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein D Sphch_2979 Bile acid:sodium symporter K14347 SLC10A7; solute carrier family 10 (sodium/bile acid cotransporter), member 7 D Sphch_0423 MATE efflux family protein K26939 norM; MATE family, multidrug efflux pump D Sphch_0049 MATE efflux family protein K26937 dinF; MATE family, multidrug efflux pump D Sphch_1211 sugar transporter K08139 HXT; MFS transporter, SP family, sugar:H+ symporter D Sphch_1292 major facilitator superfamily MFS_1 K02429 fucP; MFS transporter, FHS family, L-fucose permease D Sphch_2774 glucose/galactose transporter K02429 fucP; MFS transporter, FHS family, L-fucose permease D Sphch_2496 glucose/galactose transporter K02429 fucP; MFS transporter, FHS family, L-fucose permease D Sphch_0711 General substrate transporter K03761 kgtP; MFS transporter, MHS family, alpha-ketoglutarate permease D Sphch_3098 d-galactonate transporter K03535 gudP; MFS transporter, ACS family, glucarate transporter D Sphch_3081 major facilitator superfamily MFS_1 K08191 exuT; MFS transporter, ACS family, aldohexuronate transporter D Sphch_1721 major facilitator superfamily MFS_1 K02575 NRT2; MFS transporter, NNP family, nitrate/nitrite transporter D Sphch_0662 major facilitator superfamily MFS_1 K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG D Sphch_2295 drug resistance transporter, Bcr/CflA subfamily K07552 bcr; MFS transporter, DHA1 family, multidrug resistance protein D Sphch_1724 drug resistance transporter, EmrB/QacA subfamily K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein D Sphch_2939 drug resistance transporter, EmrB/QacA subfamily K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein D Sphch_3861 drug resistance transporter, EmrB/QacA subfamily K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein D Sphch_2918 major facilitator superfamily MFS_1 K08369 ydjE; MFS transporter, putative metabolite:H+ symporter D Sphch_2924 major facilitator superfamily MFS_1 K08369 ydjE; MFS transporter, putative metabolite:H+ symporter D Sphch_1602 PTSINtr with GAF domain, PtsP K08484 ptsP; phosphotransferase system, enzyme I, PtsP [EC:2.7.3.9] D Sphch_1628 Phosphotransferase system, phosphocarrier protein HPr K02784 ptsH; phosphocarrier protein HPr D Sphch_1627 PTS system fructose subfamily IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D Sphch_2230 putative PTS IIA-like nitrogen-regulatory protein PtsN K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-] D Sphch_1097 ammonium transporter K03320 amt; ammonium transporter, Amt family D Sphch_1940 ammonium transporter K03320 amt; ammonium transporter, Amt family D Sphch_0221 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_3179 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_2017 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_2132 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_4048 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_4017 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_2844 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_1578 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_0490 Glutathione S-transferase domain protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Sphch_1658 Large-conductance mechanosensitive channel K03282 mscL; large conductance mechanosensitive channel D Sphch_2434 magnesium transporter K06213 mgtE; magnesium transporter D Sphch_2620 flagellar motor stator protein MotA K02556 motA; chemotaxis protein MotA D Sphch_2632 MotA/TolQ/ExbB proton channel K02556 motA; chemotaxis protein MotA D Sphch_2619 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB D Sphch_2885 MotA/TolQ/ExbB proton channel K03561 exbB; biopolymer transport protein ExbB D Sphch_2886 Biopolymer transport protein ExbD/TolR K03559 exbD; biopolymer transport protein ExbD D Sphch_2887 Biopolymer transport protein ExbD/TolR K03559 exbD; biopolymer transport protein ExbD D Sphch_1592 Biopolymer transport protein ExbD/TolR K03559 exbD; biopolymer transport protein ExbD D Sphch_2047 protein TolQ K03562 tolQ; biopolymer transport protein TolQ D Sphch_2048 protein TolR K03560 tolR; biopolymer transport protein TolR D Sphch_1729 Mg2 transporter protein CorA family protein K16074 zntB; zinc transporter D Sphch_0293 CrcB-like protein K06199 crcB; fluoride exporter D Sphch_2833 protein of unknown function DUF21 K03699 tlyC; magnesium and cobalt exporter, CNNM family D Sphch_1763 putative outer membrane protein K16079 omp31; outer membrane immunogenic protein D Sphch_0255 putative outer membrane protein K16079 omp31; outer membrane immunogenic protein D Sphch_1530 hypothetical protein K16079 omp31; outer membrane immunogenic protein D Sphch_2788 phosphate-selective porin O and P K07221 oprO_P; phosphate-selective porin OprO and OprP D Sphch_1294 OmpA/MotB domain protein K03286 TC.OOP; OmpA-OmpF porin, OOP family D Sphch_0217 OmpA/MotB domain protein K03286 TC.OOP; OmpA-OmpF porin, OOP family D Sphch_0377 OmpA/MotB domain protein K03286 TC.OOP; OmpA-OmpF porin, OOP family D Sphch_2217 membrane protein involved in aromatic hydrocarbon degradation K06076 fadL; long-chain fatty acid transport protein D Sphch_3912 membrane protein involved in aromatic hydrocarbon degradation K06076 fadL; long-chain fatty acid transport protein D Sphch_2975 outer membrane autotransporter barrel domain protein K19231 bmaC; fibronectin-binding autotransporter adhesin D Sphch_2682 outer membrane autotransporter barrel domain protein K19231 bmaC; fibronectin-binding autotransporter adhesin D Sphch_2782 TonB-dependent siderophore receptor K16090 fiu; catecholate siderophore receptor D Sphch_3120 TonB-dependent receptor plug K16090 fiu; catecholate siderophore receptor D Sphch_1715 TonB-dependent receptor K16092 btuB; vitamin B12 transporter D Sphch_2551 TonB-dependent receptor plug K16089 TC.FEV.OM2; outer membrane receptor for ferrienterochelin and colicins D Sphch_3377 TonB-dependent receptor plug K16089 TC.FEV.OM2; outer membrane receptor for ferrienterochelin and colicins D Sphch_0509 TonB-dependent heme/hemoglobin receptor family protein K16087 TC.FEV.OM3; hemoglobin/transferrin/lactoferrin receptor protein D Sphch_0455 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_0513 TonB-dependent siderophore receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_0267 TonB-dependent receptor plug K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_0332 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_0434 TonB-dependent receptor plug K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_0059 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_0149 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_0153 TonB-dependent siderophore receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_1042 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_2087 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_1394 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_2116 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_2131 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3072 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3074 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3170 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3985 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3223 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_4039 TonB-dependent receptor plug K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_1735 TonB-dependent receptor plug K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_1849 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_1860 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3324 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3004 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3908 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3941 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3958 TonB-dependent receptor plug K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_4018 TonB-dependent receptor plug K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_4027 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_1633 TonB-dependent receptor plug K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_2571 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3557 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3561 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3628 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3685 TonB-dependent receptor plug K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3737 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3815 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3818 TonB-dependent siderophore receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3856 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_2489 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_2498 TonB-dependent siderophore receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3350 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3531 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3551 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3648 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3457 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3328 TonB-dependent receptor plug K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_2776 TonB-dependent receptor plug K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_2956 TonB-dependent receptor plug K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3947 TonB-dependent siderophore receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3372 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_4050 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_2932 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3773 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3845 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3971 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_4002 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_4074 TonB-dependent receptor plug K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_2544 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_2588 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_2607 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3806 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3874 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_2501 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3456 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3465 TonB-dependent receptor plug K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_0680 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_0580 Secretin/TonB short domain protein K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_0334 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_0148 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_0167 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_1291 TonB-dependent receptor plug K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_2110 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_2237 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_0983 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3099 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3134 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3280 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_3283 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein D Sphch_4104 outer membrane efflux protein K15725 czcC; outer membrane protein, heavy metal efflux system D Sphch_4087 outer membrane efflux protein K15725 czcC; outer membrane protein, heavy metal efflux system D Sphch_1575 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein D Sphch_3025 outer membrane efflux protein K12543 lapE; outer membrane protein, adhesin transport system D Sphch_0378 type I secretion outer membrane protein, TolC family K12543 lapE; outer membrane protein, adhesin transport system D Sphch_3709 RND efflux system, outer membrane lipoprotein, NodT family K18300 oprN; outer membrane protein, multidrug efflux system D Sphch_2096 RND efflux system, outer membrane lipoprotein, NodT family K18300 oprN; outer membrane protein, multidrug efflux system D Sphch_3746 RND efflux system, outer membrane lipoprotein, NodT family K18139 oprM; outer membrane protein, multidrug efflux system D Sphch_1044 RND efflux system, outer membrane lipoprotein, NodT family K18139 oprM; outer membrane protein, multidrug efflux system D Sphch_2940 RND efflux system, outer membrane lipoprotein, NodT family K18904 nodT; outer membrane protein, multidrug efflux system D Sphch_0481 polysaccharide export protein K01991 wza; polysaccharide biosynthesis/export protein D Sphch_0392 polysaccharide export protein K01991 wza; polysaccharide biosynthesis/export protein D Sphch_1238 polysaccharide export protein K01991 wza; polysaccharide biosynthesis/export protein D Sphch_0968 polysaccharide export protein K01991 wza; polysaccharide biosynthesis/export protein D Sphch_2183 polysaccharide export protein K01991 wza; polysaccharide biosynthesis/export protein D Sphch_2696 polysaccharide export protein K01991 wza; polysaccharide biosynthesis/export protein D Sphch_1330 outer membrane protein assembly complex, YaeT protein K07277 SAM50; outer membrane protein insertion porin family D Sphch_0056 Pyrrolo-quinoline quinone repeat-containing protein K17713 bamB; outer membrane protein assembly factor BamB D Sphch_1245 outer membrane assembly lipoprotein YfiO K05807 bamD; outer membrane protein assembly factor BamD D Sphch_0252 surface antigen (D15) K07278 tamA; translocation and assembly module TamA D Sphch_1783 surface antigen (D15) K07278 tamA; translocation and assembly module TamA D Sphch_0253 protein of unknown function DUF490 K09800 tamB; translocation and assembly module TamB D Sphch_1784 protein of unknown function DUF490 K09800 tamB; translocation and assembly module TamB D Sphch_0342 putative exoprotein K09800 tamB; translocation and assembly module TamB D Sphch_2561 OstA family protein K09774 lptA; lipopolysaccharide export system protein LptA D Sphch_2562 protein of unknown function DUF1239 K11719 lptC; lipopolysaccharide export system protein LptC D Sphch_1582 Organic solvent tolerance protein K04744 lptD; LPS-assembly protein D Sphch_2243 Protein of unknown function DUF2159, secreted K03643 lptE; LPS-assembly lipoprotein D Sphch_1061 CBS domain containing protein K06189 corC; hemolysin (HlyC) family protein D Sphch_4097 cation efflux protein K16264 czcD; cobalt-zinc-cadmium efflux system protein D Sphch_4098 ZIP-family zinc transporter K07238 TC.ZIP; zinc transporter, ZIP family D Sphch_4102 heavy metal efflux pump, CzcA family K15726 czcA; heavy metal efflux system protein D Sphch_4089 heavy metal efflux pump, CzcA family K07787 cusA; copper/silver efflux system protein D Sphch_3747 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family K18138 acrB; multidrug efflux pump D Sphch_1378 acriflavin resistance protein K18138 acrB; multidrug efflux pump D Sphch_1045 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family K18138 acrB; multidrug efflux pump D Sphch_0290 RarD protein, DMT superfamily transporter K05786 rarD; chloramphenicol-sensitive protein RarD D Sphch_2785 C4-dicarboxylate transport protein K11103 dctA; aerobic C4-dicarboxylate transport protein D Sphch_0124 Na(+)/H(+) antiporter nhaA K03313 nhaA; Na+:H+ antiporter, NhaA family D Sphch_3690 sodium/hydrogen exchanger K24160 NHA1; sodium/hydrogen antiporter D Sphch_1120 sodium/hydrogen exchanger K11747 kefB; glutathione-regulated potassium-efflux system protein KefB D Sphch_0647 sodium/hydrogen exchanger K03455 KEA1_2_3; K+:H+ antiporter D Sphch_2989 sodium/hydrogen exchanger K26735 KEA4_5_6; K+:H+ antiporter D Sphch_0330 chromate transporter, chromate ion transporter (CHR) family K07240 chrA; chromate transporter D Sphch_3770 high-affinity nickel-transporter K07241 hoxN; nickel/cobalt transporter (NiCoT) family protein D Sphch_4129 arsenical-resistance protein K03325 ACR3; arsenite transporter D Sphch_0005 integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase D Sphch_0799 Low affinity potassium transport system protein kup K03549 kup; KUP system potassium uptake protein D Sphch_2950 Low affinity potassium transport system protein kup K03549 kup; KUP system potassium uptake protein D Sphch_1547 protein of unknown function DUF165 K09125 yhhQ; queuosine precursor transporter D Sphch_2824 protein of unknown function DUF165 K09125 yhhQ; queuosine precursor transporter D Sphch_1137 protein of unknown function DUF125 transmembrane K22736 VIT; vacuolar iron transporter family protein D Sphch_2830 multiple antibiotic resistance (MarC)-related protein K05595 marC; multiple antibiotic resistance protein D Sphch_1424 cell cycle protein K03588 ftsW; cell division protein FtsW D Sphch_2365 hypothetical protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family D Sphch_1905 protein of unknown function UPF0016 K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family D Sphch_4106 iron permease FTR1 K07243 FTR; high-affinity iron transporter D Sphch_0508 TonB family protein K03832 tonB; periplasmic protein TonB D Sphch_2373 TonB family protein K03832 tonB; periplasmic protein TonB D Sphch_3119 TonB family protein K03832 tonB; periplasmic protein TonB D Sphch_2884 TonB family protein K03832 tonB; periplasmic protein TonB D Sphch_3945 TonB family protein K03832 tonB; periplasmic protein TonB D Sphch_2051 peptidoglycan-associated lipoprotein K03640 pal; peptidoglycan-associated lipoprotein D Sphch_2050 Protein tolB K03641 tolB; TolB protein D Sphch_2386 Pyrophosphate-energized proton pump K15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1] D Sphch_1725 efflux pump membrane protein K03543 emrA; membrane fusion protein, multidrug efflux system D Sphch_2938 secretion protein HlyD family protein K03543 emrA; membrane fusion protein, multidrug efflux system D Sphch_3862 secretion protein HlyD family protein K03543 emrA; membrane fusion protein, multidrug efflux system D Sphch_0819 type I secretion membrane fusion protein, HlyD family K12537 hasE; membrane fusion protein, type I secretion system D Sphch_4103 efflux transporter, RND family, MFP subunit K15727 czcB; membrane fusion protein, heavy metal efflux system D Sphch_4088 efflux transporter, RND family, MFP subunit K07798 cusB; membrane fusion protein, copper/silver efflux system D Sphch_0381 type I secretion membrane fusion protein, HlyD family K12542 lapC; membrane fusion protein, adhesin transport system D Sphch_3023 type I secretion membrane fusion protein, HlyD family K12542 lapC; membrane fusion protein, adhesin transport system D Sphch_3711 efflux transporter, RND family, MFP subunit K18901 bpeE; membrane fusion protein, multidrug efflux system D Sphch_1379 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Sphch_1046 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Sphch_3748 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Sphch_0393 capsular exopolysaccharide family K16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3] D Sphch_2194 lipopolysaccharide biosynthesis protein K16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3] D Sphch_0478 capsular exopolysaccharide family K16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3] D Sphch_1236 putative exopolysaccharide biosynthesis protein K00903 epsB; protein-tyrosine kinase [EC:2.7.10.3] D Sphch_0971 putative capsular polysaccharide biosynthesis protein K00903 epsB; protein-tyrosine kinase [EC:2.7.10.3] D Sphch_1237 polysaccharide chain length determinant protein, PEP-CTERM locus subfamily K25590 epsF; protein tyrosine kinase modulator D Sphch_0970 lipopolysaccharide biosynthesis protein K25590 epsF; protein tyrosine kinase modulator D Sphch_2299 FeoA family protein K04758 feoA; ferrous iron transport protein A D Sphch_2300 ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B D Sphch_1377 TspO and MBR like protein K05770 TSPO; translocator protein D Sphch_0803 cytochrome c-type biogenesis protein CcmF K02198 ccmF; cytochrome c-type biogenesis protein CcmF D Sphch_3692 MgtC/SapB transporter K07507 mgtC; putative Mg2+ transporter-C (MgtC) family protein D Sphch_4179 copper resistance D domain protein K07245 pcoD; copper resistance protein D D Sphch_4180 copper resistance protein CopC K07156 copC; copper resistance protein C D Sphch_3812 MltA-interacting MipA family protein K07274 mipA; MipA family protein C 02044 Secretion system [BR:sch02044] D Sphch_1575 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein D Sphch_0818 type I secretion system ATPase K12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase D Sphch_0819 type I secretion membrane fusion protein, HlyD family K12537 hasE; membrane fusion protein, type I secretion system D Sphch_0379 type I secretion system ATPase K12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB D Sphch_3024 Peptide-transporting ATPase K12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB D Sphch_0381 type I secretion membrane fusion protein, HlyD family K12542 lapC; membrane fusion protein, adhesin transport system D Sphch_3023 type I secretion membrane fusion protein, HlyD family K12542 lapC; membrane fusion protein, adhesin transport system D Sphch_3025 outer membrane efflux protein K12543 lapE; outer membrane protein, adhesin transport system D Sphch_0378 type I secretion outer membrane protein, TolC family K12543 lapE; outer membrane protein, adhesin transport system D Sphch_1234 secretion ATPase, PEP-CTERM locus subfamily K02450 gspA; general secretion pathway protein A D Sphch_1281 type II secretory pathway component PulC K02452 gspC; general secretion pathway protein C D Sphch_1280 general secretion pathway protein D K02453 gspD; general secretion pathway protein D D Sphch_1279 general secretory pathway protein E K02454 gspE; general secretion pathway protein E [EC:7.4.2.8] D Sphch_1278 general secretion pathway protein F K02455 gspF; general secretion pathway protein F D Sphch_1277 general secretion pathway protein G K02456 gspG; general secretion pathway protein G D Sphch_1276 general secretion pathway protein H K02457 gspH; general secretion pathway protein H D Sphch_1275 general secretion pathway protein I K02458 gspI; general secretion pathway protein I D Sphch_1274 general secretion pathway protein J K02459 gspJ; general secretion pathway protein J D Sphch_1273 type II secretory pathway component PulK K02460 gspK; general secretion pathway protein K D Sphch_1272 General secretion pathway L K02461 gspL; general secretion pathway protein L D Sphch_1271 General secretion pathway M protein K02462 gspM; general secretion pathway protein M D Sphch_1270 type II secretion system protein N K02463 gspN; general secretion pathway protein N D Sphch_1269 Prepilin peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D Sphch_0367 peptidase A24A prepilin type IV K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43] D Sphch_1365 peptidase A24A prepilin type IV K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43] D Sphch_0355 Flp pilus assembly protein CpaB K02279 cpaB; pilus assembly protein CpaB D Sphch_1366 Flp pilus assembly protein CpaB K02279 cpaB; pilus assembly protein CpaB D Sphch_3214 Flp pilus assembly protein CpaB K02279 cpaB; pilus assembly protein CpaB D Sphch_0356 type II and III secretion system protein K02280 cpaC; pilus assembly protein CpaC D Sphch_1367 type II and III secretion system protein K02280 cpaC; pilus assembly protein CpaC D Sphch_3213 type II and III secretion system protein K02280 cpaC; pilus assembly protein CpaC D Sphch_1368 Pilus biogenesis CpaD-related protein K02281 cpaD; pilus assembly protein CpaD D Sphch_0361 Flp pilus assembly protein ATPase CpaE K02282 cpaE; pilus assembly protein CpaE D Sphch_1369 Flp pilus assembly protein ATPase CpaE K02282 cpaE; pilus assembly protein CpaE D Sphch_3212 response regulator receiver protein K02282 cpaE; pilus assembly protein CpaE D Sphch_0064 type II secretion system protein E K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] D Sphch_0362 type II secretion system protein E K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] D Sphch_3211 type II secretion system protein E K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] D Sphch_0363 Type II secretion system F domain protein K12510 tadB; tight adherence protein B D Sphch_1370 Type II secretion system F domain protein K12510 tadB; tight adherence protein B D Sphch_3210 Type II secretion system F domain protein K12510 tadB; tight adherence protein B D Sphch_0364 Type II secretion system F domain protein K12511 tadC; tight adherence protein C D Sphch_1371 Type II secretion system F domain protein K12511 tadC; tight adherence protein C D Sphch_3209 Type II secretion system F domain protein K12511 tadC; tight adherence protein C D Sphch_3207 Protein of unknown function DUF2134, membrane K27080 tadG; tight adherence protein G D Sphch_0353 Flp pilus assembly protein pilin Flp K02651 flp; pilus assembly protein Flp/PilA D Sphch_0354 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA D Sphch_1318 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA D Sphch_1319 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA D Sphch_3206 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA D Sphch_2826 protein of unknown function YGGT K02221 yggT; YggT family protein D Sphch_1746 ComEC/Rec2-related protein K02238 comEC; competence protein ComEC D Sphch_2638 flagellar biosynthesis protein FlhA K02400 flhA; flagellar biosynthesis protein FlhA D Sphch_2658 type III secretion exporter K02401 flhB; flagellar biosynthesis protein FlhB D Sphch_2645 flagellar M-ring protein FliF K02409 fliF; flagellar M-ring protein FliF D Sphch_2647 flagellar biosynthetic protein FliH K02411 fliH; flagellar assembly protein FliH D Sphch_2648 ATPase, FliI/YscN family K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] D Sphch_2653 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Sphch_2654 flagellar biogenesis protein FliO K02418 fliO; flagellar protein FliO/FliZ D Sphch_2655 flagellar biosynthetic protein FliP K02419 fliP; flagellar biosynthesis protein FliP D Sphch_2656 flagellar biosynthetic protein FliQ K02420 fliQ; flagellar biosynthesis protein FliQ D Sphch_2657 flagellar biosynthetic protein FliR K02421 fliR; flagellar biosynthesis protein FliR D Sphch_4164 Lytic transglycosylase catalytic K03194 virB1; type IV secretion system protein VirB1 D Sphch_1489 Conjugal transfer protein TrbC K03197 virB2; type IV secretion system protein VirB2 D Sphch_4163 Conjugal transfer protein TrbC K03197 virB2; type IV secretion system protein VirB2 D Sphch_1488 type IV secretory pathway VirB3 family protein K03198 virB3; type IV secretion system protein VirB3 D Sphch_4162 type IV secretory pathway VirB3 family protein K03198 virB3; type IV secretion system protein VirB3 D Sphch_1487 type IV secretion/conjugal transfer ATPase, VirB4 family K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8] D Sphch_4161 type IV secretion/conjugal transfer ATPase, VirB4 family K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8] D Sphch_4160 type IV secretion system family protein K03200 virB5; type IV secretion system protein VirB5 D Sphch_4159 TrbL/VirB6 plasmid conjugal transfer protein K03201 virB6; type IV secretion system protein VirB6 D Sphch_1485 VirB8 family protein K03203 virB8; type IV secretion system protein VirB8 D Sphch_4158 VirB8 family protein K03203 virB8; type IV secretion system protein VirB8 D Sphch_1484 Conjugal transfer protein TrbG/VirB9/CagX K03204 virB9; type IV secretion system protein VirB9 D Sphch_4157 P-type conjugative transfer protein VirB9 K03204 virB9; type IV secretion system protein VirB9 D Sphch_1483 conjugation TrbI family protein K03195 virB10; type IV secretion system protein VirB10 D Sphch_4156 conjugation TrbI family protein K03195 virB10; type IV secretion system protein VirB10 D Sphch_1482 P-type DNA transfer ATPase VirB11 K03196 virB11; type IV secretion system protein VirB11 [EC:7.4.2.8] D Sphch_4155 P-type DNA transfer ATPase VirB11 K03196 virB11; type IV secretion system protein VirB11 [EC:7.4.2.8] D Sphch_2733 TRAG family protein K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8] D Sphch_4154 TRAG family protein K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8] D Sphch_0881 DNA transfer and F pilus assembly protein TraG K12056 traG; conjugal transfer mating pair stabilization protein TraG D Sphch_0878 thioredoxin-related protein K12057 traF; conjugal transfer pilus assembly protein TraF D Sphch_0875 mating pair stabilization protein TraN K12058 traN; conjugal transfer mating pair stabilization protein TraN D Sphch_0876 Type-F conjugative transfer system pilin assembly protein TrbC K12059 trbC; conjugal transfer pilus assembly protein TrbC D Sphch_0873 TraU family protein K12060 traU; conjugal transfer pilus assembly protein TraU D Sphch_0872 plasmid transfer protein TraW K12061 traW; conjugal transfer pilus assembly protein TraW D Sphch_0877 type IV secretory pathway protease TraF-like protein K12062 trbI; conjugal transfer pilin signal peptidase TrbI D Sphch_0867 type IV secretory pathway VirB4 component K12063 traC; conjugal transfer ATP-binding protein TraC D Sphch_0866 Type IV conjugative transfer system protein TraV K12064 traV; conjugal transfer pilus assembly protein TraV D Sphch_0865 conjugal transfer protein TraB K12065 traB; conjugal transfer pilus assembly protein TraB D Sphch_0864 hypothetical protein K12066 traK; conjugal transfer pilus assembly protein TraK D Sphch_0863 putative sex pilus assembly and synthesis protein K12067 traE; conjugal transfer pilus assembly protein TraE D Sphch_0860 disulfide bond isomerase, DsbC/G K03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1] D Sphch_0880 TraH family protein K12072 traH; conjugative transfer pilus assembly protein TraH D Sphch_2735 P-type conjugative transfer ATPase TrbB K20527 trbB; type IV secretion system protein TrbB [EC:7.4.2.8] D Sphch_2518 hypothetical protein K20528 trbC; type IV secretion system protein TrbC D Sphch_2736 Conjugal transfer protein TrbC K20528 trbC; type IV secretion system protein TrbC D Sphch_2737 putative conjugal transfer TrbD transmembrane protein K20529 trbD; type IV secretion system protein TrbD D Sphch_2738 CagE, TrbE, VirB component of type IV transporter system, conserved region K20530 trbE; type IV secretion system protein TrbE [EC:7.4.2.8] D Sphch_2741 conjugal transfer protein TrbF K20531 trbF; type IV secretion system protein TrbF D Sphch_2742 P-type conjugative transfer protein TrbG K20532 trbG; type IV secretion system protein TrbG D Sphch_2743 conjugation TrbI family protein K20533 trbI; type IV secretion system protein TrbI D Sphch_2739 P-type conjugative transfer protein TrbJ K20266 trbJ; type IV secretion system protein TrbJ D Sphch_2740 P-type conjugative transfer protein TrbL K07344 trbL; type IV secretion system protein TrbL D Sphch_0723 Protein translocase subunit secA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Sphch_0006 Protein-export protein secB K03071 secB; preprotein translocase subunit SecB D Sphch_1842 protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD D Sphch_2984 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Sphch_1841 protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF D Sphch_1260 preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Sphch_1809 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Sphch_1639 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Sphch_1644 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Sphch_1843 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Sphch_2908 Membrane protein oxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase D Sphch_1440 Sec-independent protein translocase protein tatA/E-like protein K03116 tatA; sec-independent protein translocase protein TatA D Sphch_1439 twin-arginine translocation protein, TatB subunit K03117 tatB; sec-independent protein translocase protein TatB D Sphch_1438 Sec-independent protein translocase, TatC subunit K03118 tatC; sec-independent protein translocase protein TatC C 02042 Bacterial toxins [BR:sch02042] D Sphch_2833 protein of unknown function DUF21 K03699 tlyC; magnesium and cobalt exporter, CNNM family C 02022 Two-component system [BR:sch02022] D Sphch_1536 histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D Sphch_1542 two component transcriptional regulator PhoB, winged helix family K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB D Sphch_1027 osmosensitive K+ channel signal transduction histidine kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3] D Sphch_1028 two component transcriptional regulator, winged helix family K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE D Sphch_1624 integral membrane sensor signal transduction histidine kinase K14980 chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3] D Sphch_1623 two component transcriptional regulator, winged helix family K14981 chvI; two-component system, OmpR family, response regulator ChvI D Sphch_3413 response regulator receiver protein K02483 K02483; two-component system, OmpR family, response regulator D Sphch_1141 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator D Sphch_2603 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator D Sphch_3750 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator D Sphch_2493 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator D Sphch_1385 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator D Sphch_1389 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator D Sphch_2191 two component transcriptional regulator, LuxR family K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL D Sphch_0141 two component transcriptional regulator, LytTR family K08083 algR; two-component system, LytTR family, response regulator AlgR D Sphch_0142 putative signal transduction histidine kinase K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3] D Sphch_2800 two component transcriptional regulator, LytTR family K02477 K02477; two-component system, LytTR family, response regulator D Sphch_0703 signal transduction histidine kinase, nitrogen specific, NtrB K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3] D Sphch_0704 nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG D Sphch_0705 multi-sensor signal transduction histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] D Sphch_0706 two component, sigma54 specific, transcriptional regulator, Fis family K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX D Sphch_1155 two component, sigma54 specific, transcriptional regulator, Fis family K02481 flgR; two-component system, NtrC family, response regulator D Sphch_1656 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Sphch_1654 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Sphch_1653 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Sphch_2281 response regulator receiver protein K11443 divK; two-component system, cell cycle response regulator DivK D Sphch_1787 multi-sensor hybrid histidine kinase K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3] D Sphch_0261 two component transcriptional regulator, winged helix family K13584 ctrA; two-component system, cell cycle response regulator CtrA D Sphch_2786 response regulator receiver protein K13589 cpdR; two-component system, cell cycle response regulator CpdR D Sphch_0894 multi-sensor signal transduction histidine kinase K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3] D Sphch_4187 PAS/PAC sensor signal transduction histidine kinase K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3] D Sphch_3367 PAS/PAC sensor signal transduction histidine kinase K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3] D Sphch_0893 two component transcriptional regulator, LuxR family K14987 fixJ; two-component system, LuxR family, response regulator FixJ D Sphch_4188 two component transcriptional regulator, LuxR family K14987 fixJ; two-component system, LuxR family, response regulator FixJ D Sphch_3366 two component transcriptional regulator, LuxR family K14987 fixJ; two-component system, LuxR family, response regulator FixJ D Sphch_4176 two component transcriptional regulator, LuxR family K14987 fixJ; two-component system, LuxR family, response regulator FixJ D Sphch_2643 sigma54 specific transcriptional regulator, Fis family K10943 flrC; two-component system, response regulator FlrC D Sphch_1105 integral membrane sensor signal transduction histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3] D Sphch_1106 two component transcriptional regulator, Fis family K15012 regA; two-component system, response regulator RegA D Sphch_3519 Hpt domain protein K20976 hptB; histidine phosphotransfer protein HptB D Sphch_0053 Hpt domain protein K20976 hptB; histidine phosphotransfer protein HptB D Sphch_1246 signal transduction histidine kinase K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3] D Sphch_1163 signal transduction histidine kinase K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3] D Sphch_0661 response regulator receiver K22010 pdtaR; two-component system, response regulator PdtaR D Sphch_1722 ABC-type transport system periplasmic component K22067 nasS; two-component system, oxyanion-binding sensor D Sphch_1723 response regulator receiver and ANTAR domain protein K07183 nasT; two-component system, response regulator / RNA-binding antiterminator D Sphch_3520 integral membrane sensor hybrid histidine kinase K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] C 02035 Bacterial motility proteins [BR:sch02035] D Sphch_1656 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Sphch_1655 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW D Sphch_1652 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Sphch_1653 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Sphch_1654 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Sphch_1699 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Sphch_0531 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Sphch_0188 methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor K03406 mcp; methyl-accepting chemotaxis protein D Sphch_3174 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Sphch_2647 flagellar biosynthetic protein FliH K02411 fliH; flagellar assembly protein FliH D Sphch_2648 ATPase, FliI/YscN family K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] D Sphch_2654 flagellar biogenesis protein FliO K02418 fliO; flagellar protein FliO/FliZ D Sphch_2655 flagellar biosynthetic protein FliP K02419 fliP; flagellar biosynthesis protein FliP D Sphch_2656 flagellar biosynthetic protein FliQ K02420 fliQ; flagellar biosynthesis protein FliQ D Sphch_2657 flagellar biosynthetic protein FliR K02421 fliR; flagellar biosynthesis protein FliR D Sphch_2638 flagellar biosynthesis protein FlhA K02400 flhA; flagellar biosynthesis protein FlhA D Sphch_2658 type III secretion exporter K02401 flhB; flagellar biosynthesis protein FlhB D Sphch_2646 flagellar motor switch protein FliG K02410 fliG; flagellar motor switch protein FliG D Sphch_2652 surface presentation of antigens (SPOA) protein K02416 fliM; flagellar motor switch protein FliM D Sphch_2653 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Sphch_2645 flagellar M-ring protein FliF K02409 fliF; flagellar M-ring protein FliF D Sphch_2624 Flagellar P-ring protein K02394 flgI; flagellar P-ring protein FlgI D Sphch_2634 flagellar protein K02386 flgA; flagellar basal body P-ring formation protein FlgA D Sphch_2625 Flagellar L-ring protein K02393 flgH; flagellar L-ring protein FlgH D Sphch_2651 flagellar basal body-associated protein FliL K02415 fliL; flagellar protein FliL D Sphch_2644 Flagellar hook-basal body complex protein fliE K02408 fliE; flagellar hook-basal body complex protein FliE D Sphch_2650 hypothetical protein K02414 fliK; flagellar hook-length control protein FliK D Sphch_2631 flagellar basal-body rod protein FlgB K02387 flgB; flagellar basal-body rod protein FlgB D Sphch_2630 flagellar basal-body rod protein FlgC K02388 flgC; flagellar basal-body rod protein FlgC D Sphch_2629 flagellar hook capping protein K02389 flgD; flagellar basal-body rod modification protein FlgD D Sphch_2627 flagellar basal-body rod protein FlgF K02391 flgF; flagellar basal-body rod protein FlgF D Sphch_2626 flagellar basal-body rod protein FlgG K02392 flgG; flagellar basal-body rod protein FlgG D Sphch_2623 Flagellar protein FlgJ K02395 flgJ; peptidoglycan hydrolase FlgJ D Sphch_2628 flagellar hook-basal body protein K02390 flgE; flagellar hook protein FlgE D Sphch_2622 flagellar hook-associated protein FlgK K02396 flgK; flagellar hook-associated protein 1 D Sphch_2621 flagellin domain protein K02397 flgL; flagellar hook-associated protein 3 FlgL D Sphch_2642 flagellin domain protein K02406 fliC; flagellin D Sphch_2660 flagellar hook-associated 2 domain-containing protein K02407 fliD; flagellar hook-associated protein 2 D Sphch_2661 flagellar protein FliS K02422 fliS; flagellar secretion chaperone FliS D Sphch_2639 RNA polymerase, sigma 28 subunit, FliA/WhiG K02405 fliA; RNA polymerase sigma factor FliA D Sphch_2620 flagellar motor stator protein MotA K02556 motA; chemotaxis protein MotA D Sphch_2632 MotA/TolQ/ExbB proton channel K02556 motA; chemotaxis protein MotA D Sphch_2619 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB D Sphch_2643 sigma54 specific transcriptional regulator, Fis family K10943 flrC; two-component system, response regulator FlrC D Sphch_2635 flagellar biosynthesis anti-sigma factor protein FlgM K02398 flgM; negative regulator of flagellin synthesis FlgM D Sphch_1269 Prepilin peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D Sphch_0353 Flp pilus assembly protein pilin Flp K02651 flp; pilus assembly protein Flp/PilA D Sphch_0354 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA D Sphch_1318 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA D Sphch_1319 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA D Sphch_3206 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA D Sphch_0367 peptidase A24A prepilin type IV K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43] D Sphch_1365 peptidase A24A prepilin type IV K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43] D Sphch_0355 Flp pilus assembly protein CpaB K02279 cpaB; pilus assembly protein CpaB D Sphch_1366 Flp pilus assembly protein CpaB K02279 cpaB; pilus assembly protein CpaB D Sphch_3214 Flp pilus assembly protein CpaB K02279 cpaB; pilus assembly protein CpaB D Sphch_0356 type II and III secretion system protein K02280 cpaC; pilus assembly protein CpaC D Sphch_1367 type II and III secretion system protein K02280 cpaC; pilus assembly protein CpaC D Sphch_3213 type II and III secretion system protein K02280 cpaC; pilus assembly protein CpaC D Sphch_1368 Pilus biogenesis CpaD-related protein K02281 cpaD; pilus assembly protein CpaD D Sphch_0361 Flp pilus assembly protein ATPase CpaE K02282 cpaE; pilus assembly protein CpaE D Sphch_1369 Flp pilus assembly protein ATPase CpaE K02282 cpaE; pilus assembly protein CpaE D Sphch_3212 response regulator receiver protein K02282 cpaE; pilus assembly protein CpaE D Sphch_0064 type II secretion system protein E K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] D Sphch_0362 type II secretion system protein E K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] D Sphch_3211 type II secretion system protein E K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:sch04812] D Sphch_0118 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins D Sphch_0845 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins D Sphch_1416 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Sphch_1417 cell division protein FtsA K03590 ftsA; cell division protein FtsA D Sphch_0431 ParA-like protein K03496 parA; chromosome partitioning protein D Sphch_2220 ATPase MipZ K03496 parA; chromosome partitioning protein D Sphch_2257 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Sphch_4141 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Sphch_4119 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Sphch_3192 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Sphch_1689 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Sphch_2258 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_3193 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_3203 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_4142 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_4118 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_4124 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_2722 ParB domain protein nuclease K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Sphch_0959 PRTRC system ParB family protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein C 04147 Exosome [BR:sch04147] D Sphch_0329 Chaperone protein htpG K04079 HSP90A; molecular chaperone HtpG D Sphch_1193 fructose-bisphosphate aldolase class-I K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] D Sphch_0551 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Sphch_1195 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Sphch_1194 Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Sphch_2867 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Sphch_0002 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D Sphch_3983 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D Sphch_1781 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D Sphch_0333 Membrane dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] D Sphch_3790 peptidase M19 renal dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] D Sphch_3481 peptidase M19 renal dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] D Sphch_2487 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Sphch_2944 Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK D Sphch_0768 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Sphch_0741 Dipeptidyl-peptidase IV K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5] D Sphch_4060 Strictosidine synthase, conserved region K01053 gnl; gluconolactonase [EC:3.1.1.17] D Sphch_3563 SMP-30/Gluconolaconase/LRE-like region-containing protein K01053 gnl; gluconolactonase [EC:3.1.1.17] D Sphch_0599 SMP-30/Gluconolaconase/LRE-like region-containing protein K01053 gnl; gluconolactonase [EC:3.1.1.17] D Sphch_1589 inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D Sphch_1831 translation elongation factor Tu K02358 tuf; elongation factor Tu D Sphch_2014 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase D Sphch_1675 histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D Sphch_2979 Bile acid:sodium symporter K14347 SLC10A7; solute carrier family 10 (sodium/bile acid cotransporter), member 7 D Sphch_0456 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0228 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_2064 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_2957 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3826 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3842 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3589 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0684 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_3839 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0604 o-succinylbenzoate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Sphch_0612 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0180 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0094 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0995 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_2108 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3248 acetyl-coenzyme A synthetase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_1080 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3982 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0756 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3830 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3834 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3054 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3883 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3885 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3931 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3997 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3506 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3670 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3497 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_3386 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Sphch_0733 Adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D Sphch_1808 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Sphch_2678 Adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Sphch_1733 Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Sphch_2601 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Sphch_0442 fumarylacetoacetase K01555 FAH; fumarylacetoacetase [EC:3.7.1.2] D Sphch_3717 fumarylacetoacetase K01555 FAH; fumarylacetoacetase [EC:3.7.1.2] D Sphch_0119 Fructose-1,6-bisphosphatase class 1 K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D Sphch_0585 1,4-alpha-glucan-branching enzyme K00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18] D Sphch_2878 Glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D Sphch_1004 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Sphch_1094 Porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D Sphch_3215 4-hydroxyphenylpyruvate dioxygenase K00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27] D Sphch_0087 pterin-4-alpha-carbinolamine dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] D Sphch_1966 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Sphch_2312 Bifunctional purine biosynthesis protein purH K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D Sphch_1350 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_1064 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_3288 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Sphch_0130 Electron transfer flavoprotein alpha subunit K03522 fixB; electron transfer flavoprotein alpha subunit D Sphch_3518 response regulator receiver protein K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] D Sphch_1088 glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D Sphch_1261 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Sphch_1133 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] C 02048 Prokaryotic defense system [BR:sch02048] D Sphch_4091 hypothetical protein K01155 E3.1.21.4; type II restriction enzyme [EC:3.1.21.4] D Sphch_1451 DNA methylase N-4/N-6 domain protein K13581 ccrM; modification methylase [EC:2.1.1.72] D Sphch_4149 restriction methylase K07317 K07317; adenine-specific DNA-methyltransferase [EC:2.1.1.72] D Sphch_1987 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Sphch_2001 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Sphch_2414 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D Sphch_0903 restriction endonuclease K07448 mrr; restriction system protein D Sphch_0906 CopG-like domain-containing protein DNA-binding protein K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB D Sphch_4191 addiction module toxin, RelE/StbE family K19157 yafQ; mRNA interferase YafQ [EC:3.1.-.-] D Sphch_4192 addiction module antitoxin, RelB/DinJ family K07473 dinJ; DNA-damage-inducible protein J D Sphch_2163 HipA N-terminal domain protein K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] D Sphch_2767 HipA domain protein K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] D Sphch_2040 phage shock protein C K03973 pspC; phage shock protein C D Sphch_1779 PspC domain protein K03973 pspC; phage shock protein C D Sphch_2041 phage shock protein B K03970 pspB; phage shock protein B D Sphch_0947 plasmid stabilization system K19092 parE1_3_4; toxin ParE1/3/4 D Sphch_2768 plasmid stabilization system K19092 parE1_3_4; toxin ParE1/3/4 D Sphch_2771 plasmid stabilization system K19092 parE1_3_4; toxin ParE1/3/4 D Sphch_0946 addiction module antidote protein, CC2985 family K07746 parD1_3_4; antitoxin ParD1/3/4 D Sphch_2770 addiction module antidote protein, CC2985 family K07746 parD1_3_4; antitoxin ParD1/3/4 D Sphch_2769 hypothetical protein K07746 parD1_3_4; antitoxin ParD1/3/4 D Sphch_1803 death-on-curing family protein K07341 doc; death on curing protein D Sphch_2766 death-on-curing family protein K07341 doc; death on curing protein D Sphch_4148 plasmid maintenance system antidote protein, XRE family K21498 higA-1; antitoxin HigA-1 D Sphch_0913 PilT protein domain protein K07062 fitB; toxin FitB [EC:3.1.-.-] D Sphch_1416 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Sphch_0118 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins D Sphch_0845 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins D Sphch_0403 DNA topoisomerase IV, A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D Sphch_0383 DNA topoisomerase IV, B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D Sphch_1747 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Sphch_2331 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Sphch_0522 protein of unknown function DUF339 K09159 cptB; antitoxin CptB D Sphch_0631 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Sphch_0632 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules [BR:sch04090] D Sphch_0741 Dipeptidyl-peptidase IV K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5] C 01504 Antimicrobial resistance genes [BR:sch01504] D Sphch_2852 peptidase M56 BlaR1 K02172 blaR1; bla regulator protein blaR1 D Sphch_2851 transcriptional repressor, CopY family K02171 blaI; BlaI family transcriptional regulator, penicillinase repressor D Sphch_2614 Beta-lactamase K17836 penP; beta-lactamase class A [EC:3.5.2.6] D Sphch_2813 Beta-lactamase K17836 penP; beta-lactamase class A [EC:3.5.2.6] D Sphch_0634 Beta-lactamase K17836 penP; beta-lactamase class A [EC:3.5.2.6] D Sphch_2482 hypothetical protein K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3] D Sphch_1379 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Sphch_1046 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Sphch_3748 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Sphch_3747 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family K18138 acrB; multidrug efflux pump D Sphch_1378 acriflavin resistance protein K18138 acrB; multidrug efflux pump D Sphch_1045 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family K18138 acrB; multidrug efflux pump D Sphch_3746 RND efflux system, outer membrane lipoprotein, NodT family K18139 oprM; outer membrane protein, multidrug efflux system D Sphch_1044 RND efflux system, outer membrane lipoprotein, NodT family K18139 oprM; outer membrane protein, multidrug efflux system D Sphch_3709 RND efflux system, outer membrane lipoprotein, NodT family K18300 oprN; outer membrane protein, multidrug efflux system D Sphch_2096 RND efflux system, outer membrane lipoprotein, NodT family K18300 oprN; outer membrane protein, multidrug efflux system D Sphch_3569 regulatory protein TetR K18301 mexL; TetR/AcrR family transcriptional regulator, mexJK operon transcriptional repressor D Sphch_4177 transcriptional regulator, MerR family K19591 cueR; MerR family transcriptional regulator, copper efflux regulator D Sphch_4083 transcriptional regulator, MerR family K19591 cueR; MerR family transcriptional regulator, copper efflux regulator D Sphch_1575 type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein D Sphch_3711 efflux transporter, RND family, MFP subunit K18901 bpeE; membrane fusion protein, multidrug efflux system C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:sch00537] D Sphch_0333 Membrane dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] D Sphch_3790 peptidase M19 renal dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] D Sphch_3481 peptidase M19 renal dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:sch03100] D Sphch_R0045 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Sphch_R0060 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Sphch_R0065 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Sphch_R0009 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Sphch_R0010 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Sphch_R0028 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Sphch_R0020 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Sphch_R0029 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Sphch_R0030 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Sphch_R0015 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Sphch_R0016 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Sphch_R0003 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Sphch_R0004 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Sphch_R0024 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Sphch_R0025 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Sphch_R0032 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Sphch_R0057 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Sphch_R0055 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Sphch_R0001 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Sphch_R0034 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Sphch_R0022 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Sphch_R0052 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Sphch_R0040 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Sphch_R0007 tRNA-His K14226 tRNA-His; tRNA His D Sphch_R0044 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Sphch_R0066 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Sphch_R0059 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Sphch_R0019 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Sphch_R0021 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Sphch_R0036 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Sphch_R0041 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Sphch_R0008 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Sphch_R0005 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Sphch_R0017 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Sphch_R0018 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Sphch_R0027 tRNA-Met K14230 tRNA-Met; tRNA Met D Sphch_R0011 tRNA-Met K14230 tRNA-Met; tRNA Met D Sphch_R0048 tRNA-Met K14230 tRNA-Met; tRNA Met D Sphch_R0049 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Sphch_R0026 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Sphch_R0012 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Sphch_R0035 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Sphch_R0013 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Sphch_R0042 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Sphch_R0050 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Sphch_R0051 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Sphch_R0056 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Sphch_R0038 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Sphch_R0039 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Sphch_R0002 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Sphch_R0054 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Sphch_R0031 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Sphch_R0053 tRNA-Val K14237 tRNA-Val; tRNA Val D Sphch_R0014 tRNA-Val K14237 tRNA-Val; tRNA Val D Sphch_R0037 tRNA-Val K14237 tRNA-Val; tRNA Val D Sphch_R0043 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Sphch_R0058 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Sphch_R0067 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Sphch_R0046 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Sphch_R0061 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Sphch_R0064 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Sphch_R0047 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Sphch_R0062 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Sphch_R0063 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Sphch_R0006 ffs; SRP RNA; RNA component of signal recognition particle K01983 ffs; SRP RNA D Sphch_R0033 rnpB; RNA component of RNaseP K01978 rnpB; M1 RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D Sphch_3620 3-oxoacyl-(acyl-carrier-protein) reductase K00046 idnO; gluconate 5-dehydrogenase [EC:1.1.1.69] D Sphch_3534 Gluconate 5-dehydrogenase K00046 idnO; gluconate 5-dehydrogenase [EC:1.1.1.69] D Sphch_3640 3-hydroxybutyryl-CoA dehydrogenase K17735 lcdH; carnitine 3-dehydrogenase [EC:1.1.1.108] D Sphch_1393 Serine 3-dehydrogenase K05886 sdh; serine 3-dehydrogenase (NADP+) [EC:1.1.1.276] D Sphch_3622 short-chain dehydrogenase/reductase SDR K16216 yueD; benzil reductase ((S)-benzoin forming) [EC:1.1.1.320] D Sphch_3656 Pyruvate dehydrogenase (acetyl-transferring) K21416 acoA; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha [EC:1.1.1.-] D Sphch_3657 Pyruvate dehydrogenase (acetyl-transferring) K21417 acoB; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta [EC:1.1.1.-] D Sphch_3333 Gluconate 2-dehydrogenase (acceptor) K26059 gtd1; glucoside 3-dehydrogenase (cytochrome c) catalytic subunit [EC:1.1.2.11] D Sphch_1258 putative glucose/sorbosone dehydrogenase K21430 yliI; aldose sugar dehydrogenase [EC:1.1.5.-] D Sphch_0592 Alcohol dehydrogenase (acceptor) K17760 qheDH; quinohemoprotein ethanol dehydrogenase [EC:1.1.9.1] D Sphch_0603 PQQ-dependent dehydrogenase, methanol/ethanol family K17760 qheDH; quinohemoprotein ethanol dehydrogenase [EC:1.1.9.1] D Sphch_2127 PQQ-dependent dehydrogenase, methanol/ethanol family K17760 qheDH; quinohemoprotein ethanol dehydrogenase [EC:1.1.9.1] D Sphch_2754 FAD linked oxidase domain protein K16653 dprE1; decaprenylphospho-beta-D-ribofuranose 2-oxidase [EC:1.1.98.3] D Sphch_0166 Coniferyl-aldehyde dehydrogenase K00154 E1.2.1.68; coniferyl-aldehyde dehydrogenase [EC:1.2.1.68] D Sphch_4061 Betaine-aldehyde dehydrogenase K23463 tgnC; (Z)-2-((N-methylformamido)methylene)-5-hydroxybutyrolactone dehydrogenase [EC:1.2.1.-] D Sphch_4053 Betaine-aldehyde dehydrogenase K23463 tgnC; (Z)-2-((N-methylformamido)methylene)-5-hydroxybutyrolactone dehydrogenase [EC:1.2.1.-] D Sphch_3224 Indolepyruvate ferredoxin oxidoreductase K04090 E1.2.7.8; indolepyruvate ferredoxin oxidoreductase [EC:1.2.7.8] D Sphch_3463 2-alkenal reductase K23256 curA; NADPH-dependent curcumin reductase [EC:1.3.1.-] D Sphch_1982 Isoquinoline 1-oxidoreductase K07302 iorA; isoquinoline 1-oxidoreductase subunit alpha [EC:1.3.99.16] D Sphch_3124 Isoquinoline 1-oxidoreductase K07303 iorB; isoquinoline 1-oxidoreductase subunit beta [EC:1.3.99.16] D Sphch_0611 NADPH-dependent F420 reductase K06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40] D Sphch_2139 NADPH-dependent F420 reductase K06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40] D Sphch_0780 Saccharopine dehydrogenase K27502 E1.5.1.55; carboxyaminopropylagmatine dehydrogenase [EC:1.5.1.55] D Sphch_0789 Electron-transferring-flavoprotein dehydrogenase K00311 ETFDH; electron-transferring-flavoprotein dehydrogenase [EC:1.5.5.1] D Sphch_0093 NADPH:quinone reductase K00344 qor; NADPH:quinone reductase [EC:1.6.5.5] D Sphch_2251 NADPH:quinone reductase K00344 qor; NADPH:quinone reductase [EC:1.6.5.5] D Sphch_0224 NAD(P)H quinone oxidoreductase, PIG3 family K00344 qor; NADPH:quinone reductase [EC:1.6.5.5] D Sphch_1552 Alcohol dehydrogenase GroES domain protein K00344 qor; NADPH:quinone reductase [EC:1.6.5.5] D Sphch_3567 NADPH:quinone reductase K00344 qor; NADPH:quinone reductase [EC:1.6.5.5] D Sphch_2133 2-nitropropane dioxygenase NPD K23948 E1.6.5.9; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9] D Sphch_3807 2-nitropropane dioxygenase NPD K23948 E1.6.5.9; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9] D Sphch_0178 2-nitropropane dioxygenase NPD K23948 E1.6.5.9; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9] D Sphch_4014 FMN-dependent NADH-azoreductase K01118 acpD; FMN-dependent NADH-azoreductase [EC:1.7.1.17] D Sphch_1464 alkyl hydroperoxide reductase, F subunit K03387 ahpF; NADH-dependent peroxiredoxin subunit F [EC:1.8.1.-] D Sphch_0229 Peptide methionine sulfoxide reductase msrA K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D Sphch_1553 Peptide methionine sulfoxide reductase msrA K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D Sphch_2245 Peptide methionine sulfoxide reductase msrB K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] D Sphch_2317 methionine-R-sulfoxide reductase K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] D Sphch_4047 Glutathione S-transferase domain protein K11209 yghU; GSH-dependent disulfide-bond oxidoreductase [EC:1.8.4.-] D Sphch_3864 Glutathione S-transferase domain protein K11209 yghU; GSH-dependent disulfide-bond oxidoreductase [EC:1.8.4.-] D Sphch_2490 Glutathione S-transferase domain protein K11209 yghU; GSH-dependent disulfide-bond oxidoreductase [EC:1.8.4.-] D Sphch_4029 Glutathione transferase K07393 ECM4; glutathionyl-hydroquinone reductase [EC:1.8.5.7] D Sphch_1524 alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D Sphch_1775 alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D Sphch_1463 peroxiredoxin K24119 ahpC; NADH-dependent peroxiredoxin subunit C [EC:1.11.1.26] D Sphch_0385 peroxiredoxin, Ohr subfamily K04063 osmC; lipoyl-dependent peroxiredoxin [EC:1.11.1.28] D Sphch_0259 Pirin domain protein K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24] D Sphch_2427 Pirin domain protein K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24] D Sphch_3694 Pirin domain protein K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24] D Sphch_3545 cysteine dioxygenase type I K24700 mdo; 3-mercaptopropionate dioxygenase [EC:1.13.11.91] D Sphch_3200 2OG-Fe(II) oxygenase K07336 K07336; PKHD-type hydroxylase [EC:1.14.11.-] D Sphch_3118 PKHD-type hydroxylase ybiX K07336 K07336; PKHD-type hydroxylase [EC:1.14.11.-] D Sphch_1619 Ferredoxin--NADP(+) reductase K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D Sphch_2141 Ferredoxin--NADP(+) reductase K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D Sphch_3964 arsenate reductase K00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1] D Sphch_4128 arsenate reductase K00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1] D Sphch_1680 arsenate reductase K00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1] D Sphch_4127 protein tyrosine phosphatase K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4] D Sphch_1609 short-chain dehydrogenase/reductase SDR K14189 dltE; uncharacterized oxidoreductase [EC:1.-.-.-] D Sphch_1576 protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] D Sphch_1766 Cyclopropane-fatty-acyl-phospholipid synthase K00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79] D Sphch_0809 Cyclopropane-fatty-acyl-phospholipid synthase K00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79] D Sphch_3527 Cyclopropane-fatty-acyl-phospholipid synthase K00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79] D Sphch_0017 GCN5-related N-acetyltransferase K22441 paiA; diamine N-acetyltransferase [EC:2.3.1.57] D Sphch_0190 Apolipoprotein N-acyltransferase K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269] D Sphch_1057 phospholipid/glycerol acyltransferase K22617 olsA; lyso-ornithine lipid O-acyltransferase [EC:2.3.1.270] D Sphch_0198 GCN5-related N-acetyltransferase K03827 yjaB; putative acetyltransferase [EC:2.3.1.-] D Sphch_0287 glutamine cyclotransferase K22757 QCT; glutaminyl-peptide cyclotransferase [EC:2.3.2.5] D Sphch_1695 Leucyl/phenylalanyl-tRNA--protein transferase K00684 aat; leucyl/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6] D Sphch_1218 arginyl-tRNA--protein transferase K21420 bpt; leucyl-tRNA---protein transferase [EC:2.3.2.29] D Sphch_0283 glycosyl transferase group 1 K00754 bshA; L-malate glycosyltransferase [EC:2.4.1.-] D Sphch_0314 Prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145] D Sphch_3117 ApbE family lipoprotein K03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180] D Sphch_2224 phosphotransferase ydiA K09773 ppsR; [pyruvate, water dikinase]-phosphate phosphotransferase / [pyruvate, water dikinase] kinase [EC:2.7.4.28 2.7.11.33] D Sphch_1525 (Glutamate--ammonia-ligase) adenylyltransferase K00982 glnE; [glutamine synthetase] adenylyltransferase / [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase [EC:2.7.7.42 2.7.7.89] D Sphch_0281 protein of unknown function UPF0061 K08997 SELENOO; protein adenylyltransferase [EC:2.7.7.108] D Sphch_3340 Carboxylesterase K03929 pnbA; para-nitrobenzyl esterase [EC:3.1.1.-] D Sphch_3962 Carboxylesterase type B K03929 pnbA; para-nitrobenzyl esterase [EC:3.1.1.-] D Sphch_3444 Carboxylesterase K03929 pnbA; para-nitrobenzyl esterase [EC:3.1.1.-] D Sphch_0099 thioesterase superfamily protein K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-] D Sphch_2046 4-hydroxybenzoyl-CoA thioesterase K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-] D Sphch_1030 putative thioesterase K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-] D Sphch_1560 thioesterase superfamily protein K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-] D Sphch_1975 thioesterase superfamily protein K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-] D Sphch_2361 protein tyrosine/serine phosphatase K01104 E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48] D Sphch_0018 putative phosphohistidine phosphatase, SixA K08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-] D Sphch_2941 metal dependent phosphohydrolase K25135 K25135; cyclic di-GMP phosphodiesterase [EC:3.1.4.-] D Sphch_0714 hydrolase, TatD family K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D Sphch_3166 nuclease (SNase domain-containing protein) K01174 nuc; micrococcal nuclease [EC:3.1.31.1] D Sphch_0978 Endo-1,4-beta-xylanase K01181 E3.2.1.8; endo-1,4-beta-xylanase [EC:3.2.1.8] D Sphch_1651 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD K01447 xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D Sphch_3605 Amidohydrolase 3 K06015 E3.5.1.81; N-acyl-D-amino-acid deacylase [EC:3.5.1.81] D Sphch_1543 Peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D Sphch_2491 polysaccharide deacetylase K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104] D Sphch_1508 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase K11206 NIT1; deaminated glutathione amidase [EC:3.5.1.128] D Sphch_2190 LmbE family protein K01463 bshB1; N-acetylglucosamine malate deacetylase 1 [EC:3.5.1.-] D Sphch_1736 Endoribonuclease L-PSP K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10] D Sphch_1895 ATPase associated with various cellular activities AAA_3 K03924 moxR; MoxR-like ATPase [EC:3.6.3.-] D Sphch_0061 protein of unknown function DUF1234 K07002 RBBP9; serine hydrolase [EC:3.-.-.-] D Sphch_0784 YjeF-related protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6] D Sphch_1093 putative acetyltransferase K01726 GAMMACA; gamma-carbonic anhydrase [EC:4.2.1.-] D Sphch_0173 Long-chain-fatty-acid--CoA ligase K12508 fcs; feruloyl-CoA synthase [EC:6.2.1.34] D Sphch_3440 Long-chain-fatty-acid--CoA ligase K12508 fcs; feruloyl-CoA synthase [EC:6.2.1.34] D Sphch_3426 cyanophycin synthetase K03802 cphA; cyanophycin synthetase [EC:6.3.2.29 6.3.2.30] D Sphch_3407 heavy metal translocating P-type ATPase K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9] D Sphch_4096 heavy metal translocating P-type ATPase K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21] C 99981 Carbohydrate metabolism D Sphch_3334 hypothetical protein K26060 gtd2; glucoside 3-dehydrogenase (cytochrome c) hitch-hiker subunit C 99982 Energy metabolism D Sphch_3723 formate dehydrogenase family accessory protein FdhD K02379 fdhD; FdhD protein D Sphch_3575 ferredoxin K04755 fdx; ferredoxin, 2Fe-2S D Sphch_3593 ferredoxin K04755 fdx; ferredoxin, 2Fe-2S D Sphch_3064 ferredoxin K04755 fdx; ferredoxin, 2Fe-2S D Sphch_1567 ferredoxin K04755 fdx; ferredoxin, 2Fe-2S D Sphch_0987 protein of unknown function DUF1271 K05337 fer; ferredoxin D Sphch_3796 protein of unknown function DUF1271 K05337 fer; ferredoxin D Sphch_1458 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K05524 fdxA; ferredoxin D Sphch_4056 Succinate dehydrogenase K13796 cobZ; tricarballylate dehydrogenase D Sphch_0129 Electron transfer flavoprotein alpha/beta-subunit K03521 fixA; electron transfer flavoprotein beta subunit C 99983 Lipid metabolism C 99984 Nucleotide metabolism C 99985 Amino acid metabolism D Sphch_2322 hypothetical protein K06203 cysZ; CysZ protein D Sphch_2238 protein of unknown function UPF0001 K06997 yggS; PLP dependent protein C 99986 Glycan metabolism D Sphch_0974 O-antigen polymerase K16567 exoQ; exopolysaccharide production protein ExoQ D Sphch_0257 hypothetical protein K08992 lapA; lipopolysaccharide assembly protein A C 99987 Cofactor metabolism D Sphch_3769 cobalamin biosynthesis protein CobW K02234 cobW; cobalamin biosynthesis protein CobW D Sphch_2914 2-polyprenylphenol 6-hydroxylase K03688 ubiB; ubiquinone biosynthesis protein D Sphch_2298 rpsU-divergently transcribed protein K18587 COQ9; ubiquinone biosynthesis protein COQ9 D Sphch_0699 cyclase/dehydrase K18588 COQ10; coenzyme Q-binding protein COQ10 C 99988 Secondary metabolism C 99999 Others D Sphch_3907 DoxX family protein K15977 K15977; putative oxidoreductase D Sphch_4019 phospholipase/Carboxylesterase K06999 K06999; phospholipase/carboxylesterase B B 09192 Unclassified: genetic information processing C 99973 Transcription D Sphch_0505 cold-shock DNA-binding domain protein K03704 cspA; cold shock protein D Sphch_2564 cold-shock DNA-binding domain protein K03704 cspA; cold shock protein D Sphch_1939 nitrogen regulatory protein P-II K04752 glnK; nitrogen regulatory protein P-II 2 C 99974 Translation D Sphch_4173 RNA-metabolising metallo-beta-lactamase K07576 K07576; metallo-beta-lactamase family protein D Sphch_0778 putative exonuclease K07577 K07577; putative mRNA 3-end processing factor C 99975 Protein processing D Sphch_2876 ATP-dependent Clp protease adapter protein clpS K06891 clpS; ATP-dependent Clp protease adaptor protein ClpS D Sphch_1016 Trigger factor K03545 tig; trigger factor D Sphch_1789 SsrA-binding protein K03664 smpB; SsrA-binding protein D Sphch_1837 Mg chelatase, subunit ChlI K07391 comM; magnesium chelatase family protein D Sphch_1265 20S proteasome A and B subunits K07395 K07395; putative proteasome-type protease D Sphch_2360 OsmC family protein K07397 yhfA; putative redox protein D Sphch_3693 OsmC family protein K07397 yhfA; putative redox protein D Sphch_2902 XshC-Cox1-family protein K07402 xdhC; xanthine dehydrogenase accessory factor C 99976 Replication and repair D Sphch_1920 hypothetical protein K07454 K07454; putative restriction endonuclease D Sphch_0341 DNA repair protein RadC K03630 radC; DNA repair protein RadC D Sphch_1915 RmuC-domain protein K09760 rmuC; DNA recombination protein RmuC D Sphch_1709 UPF0102 protein yraN K07460 yraN; putative endonuclease D Sphch_2339 Excinuclease ABC C subunit domain protein K07461 K07461; putative endonuclease D Sphch_0774 DNA protecting protein DprA K04096 smf; DNA processing protein D Sphch_0418 AAA ATPase central domain protein K07478 ycaJ; putative ATPase D Sphch_2407 Resolvase domain protein K14060 pinR; putative DNA-invertase from lambdoid prophage Rac D Sphch_4122 hypothetical protein K06919 K06919; putative DNA primase/helicase D Sphch_3032 3'-5' exonuclease, PolB-like protein K07501 K07501; 3'-5' exonuclease D Sphch_1478 transposase IS3/IS911 family protein K07483 K07483; transposase D Sphch_1959 transposase IS3/IS911 family protein K07483 K07483; transposase D Sphch_3038 transposase IS3/IS911 family protein K07483 K07483; transposase D Sphch_0515 transposase IS116/IS110/IS902 family protein K07486 K07486; transposase D Sphch_2101 transposase IS116/IS110/IS902 family protein K07486 K07486; transposase D Sphch_2400 transposase IS3/IS911 family protein K07497 K07497; putative transposase D Sphch_3706 transposase IS3/IS911 family protein K07497 K07497; putative transposase D Sphch_3420 transposase IS3/IS911 family protein K07497 K07497; putative transposase D Sphch_1477 Integrase catalytic region K07497 K07497; putative transposase D Sphch_1960 Integrase catalytic region K07497 K07497; putative transposase D Sphch_3037 Integrase catalytic region K07497 K07497; putative transposase D Sphch_2399 Integrase catalytic region K07497 K07497; putative transposase C 99979 Viral proteins C 99998 Others D Sphch_2042 phage shock protein A, PspA K03969 pspA; phage shock protein A D Sphch_0636 UPF0133 protein ybaB K09747 ebfC; nucleoid-associated protein EbfC B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D Sphch_1863 sugar transporter K03292 TC.GPH; glycoside/pentoside/hexuronide:cation symporter, GPH family D Sphch_2294 amino acid permease-associated region K03294 TC.APA; basic amino acid/polyamine antiporter, APA family D Sphch_1641 amino acid permease-associated region K03294 TC.APA; basic amino acid/polyamine antiporter, APA family D Sphch_2946 amino acid permease-associated region K03294 TC.APA; basic amino acid/polyamine antiporter, APA family D Sphch_1152 amino acid/peptide transporter K03305 TC.POT; proton-dependent oligopeptide transporter, POT family D Sphch_2569 phosphate transporter K03306 TC.PIT; inorganic phosphate transporter, PiT family D Sphch_1470 amino acid carrier protein K03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family D Sphch_0038 Na+ dependent nucleoside transporter domain protein K03317 TC.CNT; concentrative nucleoside transporter, CNT family C 99978 Cell growth D Sphch_1645 intracellular septation protein A K06190 ispZ; intracellular septation protein D Sphch_1506 Resolvase domain protein K06400 spoIVCA; site-specific DNA recombinase D Sphch_3754 SpoVR family protein K06415 spoVR; stage V sporulation protein R D Sphch_1911 Peptidase M23 K22719 envC; murein hydrolase activator C 99993 Cell motility C 99995 Signaling proteins D Sphch_2904 carbon starvation protein CstA K06200 cstA; carbon starvation protein D Sphch_0036 GTP-binding protein TypA K06207 typA; GTP-binding protein D Sphch_0629 CBS domain containing membrane protein K07168 K07168; CBS domain-containing membrane protein D Sphch_1059 PhoH family protein K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins D Sphch_3752 putative serine protein kinase, PrkA K07180 prkA; serine protein kinase D Sphch_3942 putative circadian clock protein, KaiC K08482 kaiC; circadian clock protein KaiC C 99992 Structural proteins D Sphch_3113 VacJ family lipoprotein K04754 mlaA; phospholipid-binding lipoprotein MlaA D Sphch_0200 hypothetical protein K06077 slyB; outer membrane lipoprotein SlyB D Sphch_1672 Capsule polysaccharide biosynthesis protein K07265 kpsS; capsular polysaccharide export protein D Sphch_1673 Capsule polysaccharide biosynthesis protein K07266 kpsC; capsular polysaccharide export protein D Sphch_0271 glycoside hydrolase family 25 K07273 acm; lysozyme D Sphch_3399 OmpW family protein K07275 ompW; outer membrane protein D Sphch_0812 protein of unknown function DUF481 K07283 ydiY; putative salt-induced outer membrane protein D Sphch_1618 protein of unknown function DUF107 K07340 ybbJ; inner membrane protein D Sphch_2376 efflux transporter, RND family, MFP subunit K02005 ABC.CD.TX; HlyD family secretion protein D Sphch_0804 Cytochrome c-type biogenesis protein ccmE K02197 ccmE; cytochrome c-type biogenesis protein CcmE D Sphch_0801 cytochrome C biogenesis protein K02200 ccmH; cytochrome c-type biogenesis protein CcmH D Sphch_3787 Tetratricopeptide TPR_2 repeat-containing protein K02200 ccmH; cytochrome c-type biogenesis protein CcmH D Sphch_0800 cytochrome c biogenesis factor K02200 ccmH; cytochrome c-type biogenesis protein CcmH D Sphch_1601 transcriptional regulator, XRE family K15539 rodZ; cytoskeleton protein RodZ C 99994 Others D Sphch_1541 phosphate uptake regulator, PhoU K02039 phoU; phosphate transport system protein D Sphch_1315 BFD domain protein (2Fe-2S)-binding domain protein K02192 bfd; bacterioferritin-associated ferredoxin D Sphch_2641 periplasmic glucan biosynthesis protein MdoG K03670 mdoG; periplasmic glucans biosynthesis protein D Sphch_1973 integral membrane protein, TerC family K05794 terC; tellurite resistance protein TerC D Sphch_0373 Protein ApaG K06195 apaG; ApaG protein D Sphch_1851 monooxygenase FAD-binding protein K07222 K07222; putative flavoprotein involved in K+ transport D Sphch_4063 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K07222 K07222; putative flavoprotein involved in K+ transport D Sphch_1148 copper resistance B precursor K07233 pcoB; copper resistance protein B D Sphch_4185 copper resistance B precursor K07233 pcoB; copper resistance protein B D Sphch_4195 copper resistance B precursor K07233 pcoB; copper resistance protein B D Sphch_4182 hypothetical protein K24078 cnrR; nickel and cobalt resistance protein CnrR B B 09194 Poorly characterized C 99996 General function prediction only D Sphch_0092 Colicin V production protein K03558 cvpA; membrane protein required for colicin V production D Sphch_0759 export-related chaperone CsaA K06878 K06878; tRNA-binding protein D Sphch_3188 globin K06886 glbN; hemoglobin D Sphch_0891 globin K06886 glbN; hemoglobin D Sphch_1528 Patatin K07001 K07001; NTE family protein D Sphch_1970 pyrimidine 5'-nucleotidase K07025 K07025; putative hydrolase of the HAD superfamily D Sphch_1928 Haloacid dehalogenase domain protein hydrolase K07025 K07025; putative hydrolase of the HAD superfamily D Sphch_2031 FeS assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB D Sphch_2028 SufBD protein K09015 sufD; Fe-S cluster assembly protein SufD D Sphch_1956 ribonuclease BN K07058 K07058; membrane protein D Sphch_2037 Fe-S metabolism associated SufE K02426 sufE; cysteine desulfuration protein SufE D Sphch_2235 UPF0176 protein yceA K07146 K07146; UPF0176 protein D Sphch_4131 arsenical resistance protein ArsH K11811 arsH; arsenical resistance protein ArsH D Sphch_1659 LemA family protein K03744 lemA; LemA protein D Sphch_0739 Uncharacterized conserved protein UCP020606 K08984 yjdF; putative membrane protein D Sphch_1661 protein of unknown function DUF477 K08988 K08988; putative membrane protein D Sphch_1768 protein of unknown function DUF350 K08989 K08989; putative membrane protein D Sphch_2972 hypothetical protein K08995 K08995; putative membrane protein D Sphch_3691 hypothetical protein K08995 K08995; putative membrane protein D Sphch_3433 putative outer membrane protein K08995 K08995; putative membrane protein D Sphch_2906 PhnA protein K06193 phnA; protein PhnA C 99997 Function unknown D Sphch_2440 Ankyrin K06867 K06867; uncharacterized protein D Sphch_0671 protein of unknown function DUF477 K06872 K06872; uncharacterized protein D Sphch_1660 protein of unknown function DUF477 K06872 K06872; uncharacterized protein D Sphch_0220 protein of unknown function UPF0005 K06890 K06890; uncharacterized protein D Sphch_1684 protein of unknown function UPF0005 K06890 K06890; uncharacterized protein D Sphch_1886 hypothetical protein K06893 K06893; uncharacterized protein D Sphch_3294 hypothetical protein K06893 K06893; uncharacterized protein D Sphch_3310 hypothetical protein K06893 K06893; uncharacterized protein D Sphch_0232 protein of unknown function DUF815 K06923 K06923; uncharacterized protein D Sphch_3125 CoA-binding domain protein K06929 K06929; uncharacterized protein D Sphch_2236 putative ICC-like phosphoesterase K06953 K06953; uncharacterized protein D Sphch_0435 protein of unknown function DUF861 cupin_3 K06995 K06995; uncharacterized protein D Sphch_1858 protein of unknown function DUF861 cupin_3 K06995 K06995; uncharacterized protein D Sphch_1607 Glyoxalase/bleomycin resistance protein/dioxygenase K06996 K06996; uncharacterized protein D Sphch_0630 alpha/beta hydrolase fold protein K07018 K07018; uncharacterized protein D Sphch_0896 aminoglycoside phosphotransferase K07028 K07028; uncharacterized protein D Sphch_3615 Uncharacterized conserved protein UCP07580 K07044 K07044; uncharacterized protein D Sphch_1527 protein of unknown function zinc metallopeptidase K07054 K07054; uncharacterized protein D Sphch_0922 protein of unknown function DUF132 K07063 K07063; uncharacterized protein D Sphch_0590 protein of unknown function DUF35 K07068 K07068; uncharacterized protein D Sphch_0600 protein of unknown function DUF35 K07068 K07068; uncharacterized protein D Sphch_3231 protein of unknown function DUF35 K07068 K07068; uncharacterized protein D Sphch_3668 protein of unknown function DUF35 K07068 K07068; uncharacterized protein D Sphch_3884 protein of unknown function DUF35 K07068 K07068; uncharacterized protein D Sphch_2749 plasmid stabilization system K07076 K07076; uncharacterized protein D Sphch_0396 protein of unknown function DUF81 K07090 K07090; uncharacterized protein D Sphch_1400 protein of unknown function DUF81 K07090 K07090; uncharacterized protein D Sphch_0121 protein of unknown function DUF81 K07090 K07090; uncharacterized protein D Sphch_1112 protein of unknown function DUF81 K07090 K07090; uncharacterized protein D Sphch_1577 protein of unknown function DUF81 K07090 K07090; uncharacterized protein D Sphch_2605 protein of unknown function DUF81 K07090 K07090; uncharacterized protein D Sphch_1345 metallophosphoesterase K07098 K07098; uncharacterized protein D Sphch_3863 short-chain dehydrogenase/reductase SDR K07124 K07124; uncharacterized protein D Sphch_2971 short-chain dehydrogenase/reductase SDR K07124 K07124; uncharacterized protein D Sphch_2296 Sel1 domain protein repeat-containing protein K07126 K07126; uncharacterized protein D Sphch_3521 Sel1 domain protein repeat-containing protein K07126 K07126; uncharacterized protein D Sphch_0430 Sporulation domain-containing protein K07126 K07126; uncharacterized protein D Sphch_2308 GST-related protein K07136 K07136; uncharacterized protein D Sphch_3168 FAD dependent oxidoreductase K07137 K07137; uncharacterized protein D Sphch_1314 hypothetical protein K07148 K07148; uncharacterized protein D Sphch_2840 peptidase S16 lon domain protein K07157 K07157; uncharacterized protein D Sphch_2909 UPF0161 protein yidD K08998 K08998; uncharacterized protein D Sphch_1692 protein of unknown function DUF192 K09005 K09005; uncharacterized protein D Sphch_0539 GatB/YqeY-like uncharacterized conserved protein K09117 K09117; uncharacterized protein D Sphch_2827 UPF0235 protein yggU K09131 K09131; uncharacterized protein D Sphch_2442 UPF0260 protein ycgN K09160 K09160; uncharacterized protein D Sphch_0414 protein of unknown function DUF985 K09705 K09705; uncharacterized protein D Sphch_3925 UPF0178 protein yaiI K09768 K09768; uncharacterized protein D Sphch_4043 YCII-related protein K09780 K09780; uncharacterized protein D Sphch_4046 YCII-related protein K09780 K09780; uncharacterized protein D Sphch_0424 protein of unknown function DUF808 K09781 K09781; uncharacterized protein D Sphch_3753 UPF0229 protein yeaH K09786 K09786; uncharacterized protein D Sphch_1143 protein of unknown function DUF454 K09790 K09790; uncharacterized protein D Sphch_2060 protein of unknown function DUF541 K09797 K09797; uncharacterized protein D Sphch_1139 protein of unknown function DUF541 K09807 K09807; uncharacterized protein D Sphch_3924 UPF0246 protein yaaA K09861 K09861; uncharacterized protein D Sphch_2396 UPF0243 zinc-binding protein yacG K09862 K09862; uncharacterized protein D Sphch_2276 protein of unknown function DUF482 K09919 K09919; uncharacterized protein D Sphch_1302 protein of unknown function DUF486 K09922 K09922; uncharacterized protein D Sphch_1788 Protein of unknown function DUF2062 K09928 K09928; uncharacterized protein D Sphch_3114 PepSY-associated TM helix domain protein K09939 K09939; uncharacterized protein D Sphch_2866 protein of unknown function DUF1244 K09948 K09948; uncharacterized protein D Sphch_2861 Uncharacterized conserved protein UCP028291 K09956 K09956; uncharacterized protein D Sphch_0833 GumN family protein K09973 K09973; uncharacterized protein D Sphch_0834 GumN family protein K09973 K09973; uncharacterized protein D Sphch_0344 Uncharacterized conserved protein UCP025560 K09978 K09978; uncharacterized protein D Sphch_1683 hypothetical protein K09981 K09981; uncharacterized protein D Sphch_2052 Domain of unknown function DUF1993-containing protein K09983 K09983; uncharacterized protein D Sphch_1468 protein of unknown function DUF1272 K09984 K09984; uncharacterized protein D Sphch_0309 hypothetical protein K09985 K09985; uncharacterized protein D Sphch_0407 protein of unknown function DUF1285 K09986 K09986; uncharacterized protein D Sphch_0227 protein of unknown function DUF1013 K09987 K09987; uncharacterized protein D Sphch_0530 hypothetical protein K09989 K09989; uncharacterized protein D Sphch_1574 Protein of unknown function DUF2497 K09991 K09991; uncharacterized protein D Sphch_2570 putative phosphate transport regulator K07220 K07220; uncharacterized protein D Sphch_1254 protein of unknown function DUF448 K07742 ylxR; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: April 30, 2024