+D GENES KO #

  KEGG Orthology (KO) - Streptococcus pyogenes MGAS9429 (serotype M12)

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A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:spk00010] D MGAS9429_Spy1252 glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] D MGAS9429_Spy0187 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D MGAS9429_Spy1093 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D MGAS9429_Spy1610 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D MGAS9429_Spy0499 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D MGAS9429_Spy0235 plr; glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D MGAS9429_Spy1604 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D MGAS9429_Spy1212 gpmA; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D MGAS9429_Spy0609 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D MGAS9429_Spy1092 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D MGAS9429_Spy0865 acoA; pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D MGAS9429_Spy0866 acoB; pyruvate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D MGAS9429_Spy0867 acoC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D MGAS9429_Spy0869 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D MGAS9429_Spy0991 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D MGAS9429_Spy0040 adh2; alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D MGAS9429_Spy0041 adhA; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D MGAS9429_Spy1041 pgmA; phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D MGAS9429_Spy1166 gapN; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9] D MGAS9429_Spy0468 bglA; 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D MGAS9429_Spy1128 bglA2; beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D MGAS9429_Spy1307 beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] C 00020 Citrate cycle (TCA cycle) [PATH:spk00020] D MGAS9429_Spy0869 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D MGAS9429_Spy0865 acoA; pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D MGAS9429_Spy0866 acoB; pyruvate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D MGAS9429_Spy0867 acoC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] C 00030 Pentose phosphate pathway [PATH:spk00030] D MGAS9429_Spy0187 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D MGAS9429_Spy0226 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D MGAS9429_Spy1373 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D MGAS9429_Spy1751 mipB; transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D MGAS9429_Spy1374 transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D MGAS9429_Spy1662 transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D MGAS9429_Spy0751 rpiA; ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D MGAS9429_Spy1590 deoC; deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4] D MGAS9429_Spy0752 deoB; phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7] D MGAS9429_Spy1041 pgmA; phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D MGAS9429_Spy0964 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D MGAS9429_Spy0018 prsA2; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D MGAS9429_Spy0518 kgdA; 4-Hydroxy-2-oxoglutarate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] D MGAS9429_Spy1166 gapN; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9] D MGAS9429_Spy0517 2-dehydro-3-deoxygluconokinase K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45] D MGAS9429_Spy1610 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D MGAS9429_Spy1093 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] C 00040 Pentose and glucuronate interconversions [PATH:spk00040] D MGAS9429_Spy0448 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D MGAS9429_Spy1863 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D MGAS9429_Spy0194 hasC2; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D MGAS9429_Spy1864 hasC; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D MGAS9429_Spy0153 3-keto-L-gulonate-6-phosphate decarboxylase K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85] D MGAS9429_Spy0154 L-xylulose 5-phosphate 3-epimerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22] D MGAS9429_Spy0155 araD; L-ribulose-5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4] D MGAS9429_Spy0226 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] C 00051 Fructose and mannose metabolism [PATH:spk00051] D MGAS9429_Spy1543 scrK; fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D MGAS9429_Spy1541 pmi; mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D MGAS9429_Spy1093 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D MGAS9429_Spy0716 fruB; 1-phosphofructokinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56] D MGAS9429_Spy1610 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D MGAS9429_Spy0499 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D MGAS9429_Spy0717 fruA; PTS system, fructose-specific IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D MGAS9429_Spy0897 PTS system, mannose/fructose family IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D MGAS9429_Spy1481 manL; PTS system, mannose-specific IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D MGAS9429_Spy0899 ptsC; PTS system, mannose/fructose family IIC component K02795 manY; mannose PTS system EIIC component D MGAS9429_Spy1482 manM; PTS system, mannose-specific IIC component K02795 manY; mannose PTS system EIIC component D MGAS9429_Spy0900 ptsD; PTS system, mannose/fructose family IID component K02796 manZ; mannose PTS system EIID component D MGAS9429_Spy1483 manN; PTS system, mannose-specific IID component K02796 manZ; mannose PTS system EIID component C 00052 Galactose metabolism [PATH:spk00052] D MGAS9429_Spy0194 hasC2; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D MGAS9429_Spy1864 hasC; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D MGAS9429_Spy1041 pgmA; phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D MGAS9429_Spy1252 glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] D MGAS9429_Spy1298 lacZ; beta-galactosidase K01190 lacZ; beta-galactosidase [EC:3.2.1.23] D MGAS9429_Spy1639 lacC2; tagatose-6-phosphate kinase K00917 lacC; tagatose 6-phosphate kinase [EC:2.7.1.144] D MGAS9429_Spy1093 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D MGAS9429_Spy1397 lacD1; tagatose-bisphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D MGAS9429_Spy1638 lacD2; tagatose-bisphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D MGAS9429_Spy1399 galactose-6-phosphate isomerase lacB subunit K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D MGAS9429_Spy1400 lacA1; galactose-6-phosphate isomerase lacA subunit K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D MGAS9429_Spy1640 lacB2; galactose-6-phosphate isomerase lacB subunit K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D MGAS9429_Spy1641 lacA2; galactose-6-phosphate isomerase lacA subunit K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D MGAS9429_Spy1635 lacG; 6-phospho-beta-galactosidase K01220 E3.2.1.85; 6-phospho-beta-galactosidase [EC:3.2.1.85] D MGAS9429_Spy1637 lacF; PTS system, lactose-specific IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D MGAS9429_Spy1636 lacE; PTS system, lactose-specific IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D MGAS9429_Spy1547 scrB; sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D MGAS9429_Spy0514 PTS system, N-acetylgalactosamine-specific IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-] D MGAS9429_Spy0512 agaV; PTS system, N-acetylgalactosamine-specific IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-] D MGAS9429_Spy0511 PTS system, N-acetylgalactosamine-specific IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component D MGAS9429_Spy0510 agaD; PTS system, N-acetylgalactosamine-specific IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component D MGAS9429_Spy0598 agaS; galactosamine-6-phosphate deaminase (isomerizing) K02082 agaS; D-galactosamine 6-phosphate deaminase/isomerase [EC:3.5.99.-] C 00053 Ascorbate and aldarate metabolism [PATH:spk00053] D MGAS9429_Spy0448 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D MGAS9429_Spy1863 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D MGAS9429_Spy0152 PTS system, 3-keto-L-gulonate specific IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D MGAS9429_Spy1665 transcription antiterminator, BglG family K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D MGAS9429_Spy0151 PTS system, 3-keto-L-gulonate specific IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D MGAS9429_Spy1664 PTS system, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D MGAS9429_Spy0150 PTS system, 3-keto-L-gulonate specific IIC component K03475 ulaA; ascorbate PTS system EIIC component D MGAS9429_Spy1663 putative transport protein sgaT K03475 ulaA; ascorbate PTS system EIIC component D MGAS9429_Spy0158 metal-dependent hydrolase K03476 ulaG; L-ascorbate 6-phosphate lactonase [EC:3.1.1.-] D MGAS9429_Spy0153 3-keto-L-gulonate-6-phosphate decarboxylase K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85] D MGAS9429_Spy0154 L-xylulose 5-phosphate 3-epimerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22] D MGAS9429_Spy0155 araD; L-ribulose-5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4] C 00500 Starch and sucrose metabolism [PATH:spk00500] D MGAS9429_Spy1546 scrA; PTS system, sucrose-specific IIABC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D MGAS9429_Spy1547 scrB; sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D MGAS9429_Spy0194 hasC2; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D MGAS9429_Spy1864 hasC; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D MGAS9429_Spy1756 PTS system, cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D MGAS9429_Spy1124 PTS system, cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D MGAS9429_Spy1125 PTS system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D MGAS9429_Spy1755 PTS system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D MGAS9429_Spy1754 PTS system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component D MGAS9429_Spy1122 PTS system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component D MGAS9429_Spy0468 bglA; 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D MGAS9429_Spy1128 bglA2; beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D MGAS9429_Spy1307 beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D MGAS9429_Spy1101 glgP; maltodextrin phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1] D MGAS9429_Spy1102 malM; 4-alpha-glucanotransferase K00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25] D MGAS9429_Spy1693 PTS system, glucose-specific IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208] D MGAS9429_Spy1692 endonuclease/exonuclease/phosphatase family protein K06896 mapP; maltose 6'-phosphate phosphatase [EC:3.1.3.90] D MGAS9429_Spy1795 PTS system, trehalose-specific IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D MGAS9429_Spy1794 dexS; trehalose-6-phosphate hydrolase K01226 treC; trehalose-6-phosphate hydrolase [EC:3.2.1.93] D MGAS9429_Spy1041 pgmA; phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D MGAS9429_Spy1252 glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] D MGAS9429_Spy0187 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D MGAS9429_Spy1543 scrK; fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:spk00520] D MGAS9429_Spy1388 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25] D MGAS9429_Spy1186 nagB; glucosamine-6-phosphate isomerase K02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6] D MGAS9429_Spy1543 scrK; fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D MGAS9429_Spy1090 glmS; glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D MGAS9429_Spy0878 femD; phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10] D MGAS9429_Spy0365 gcaD; glucosamine-1-phosphate acetyltransferase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D MGAS9429_Spy1151 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D MGAS9429_Spy0638 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D MGAS9429_Spy0944 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D MGAS9429_Spy0213 N-acetylmannosamine-6-phosphate 2-epimerase K01788 nanE; N-acylglucosamine-6-phosphate 2-epimerase [EC:5.1.3.9] D MGAS9429_Spy0218 nanH; N-acetylneuraminate lyase K01639 E4.1.3.3; N-acetylneuraminate lyase [EC:4.1.3.3] D MGAS9429_Spy1252 glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] D MGAS9429_Spy1041 pgmA; phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D MGAS9429_Spy0194 hasC2; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D MGAS9429_Spy1864 hasC; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D MGAS9429_Spy0448 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D MGAS9429_Spy1863 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D MGAS9429_Spy0897 PTS system, mannose/fructose family IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D MGAS9429_Spy1481 manL; PTS system, mannose-specific IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D MGAS9429_Spy0899 ptsC; PTS system, mannose/fructose family IIC component K02795 manY; mannose PTS system EIIC component D MGAS9429_Spy1482 manM; PTS system, mannose-specific IIC component K02795 manY; mannose PTS system EIIC component D MGAS9429_Spy0900 ptsD; PTS system, mannose/fructose family IID component K02796 manZ; mannose PTS system EIID component D MGAS9429_Spy1483 manN; PTS system, mannose-specific IID component K02796 manZ; mannose PTS system EIID component D MGAS9429_Spy0187 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D MGAS9429_Spy1541 pmi; mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] C 00620 Pyruvate metabolism [PATH:spk00620] D MGAS9429_Spy0865 acoA; pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D MGAS9429_Spy0866 acoB; pyruvate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D MGAS9429_Spy0867 acoC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D MGAS9429_Spy0869 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D MGAS9429_Spy1574 pfl; formate acetyltransferase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D MGAS9429_Spy0040 adh2; alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D MGAS9429_Spy0041 adhA; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D MGAS9429_Spy0095 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D MGAS9429_Spy0969 pta; phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D MGAS9429_Spy1092 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D MGAS9429_Spy1486 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D MGAS9429_Spy1490 accB; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D MGAS9429_Spy1488 accC; biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D MGAS9429_Spy1487 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D MGAS9429_Spy0296 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D MGAS9429_Spy0991 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D MGAS9429_Spy1007 ddh; D-2-hydroxyacid dehydrogenase K03778 ldhA; D-lactate dehydrogenase [EC:1.1.1.28] D MGAS9429_Spy0420 gloA; lactoylglutathione lyase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5] D MGAS9429_Spy0524 hydroxyacylglutathione hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D MGAS9429_Spy0952 NAD-dependent malic enzyme K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D MGAS9429_Spy1011 oadA1; Na+ transporting oxaloacetate decarboxylase alpha chain K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] D MGAS9429_Spy0495 ppc; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D MGAS9429_Spy0431 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0121 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy1339 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:spk00630] D MGAS9429_Spy0431 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0121 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy1339 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy1601 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MGAS9429_Spy0984 glyA; serinehydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D MGAS9429_Spy0869 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D MGAS9429_Spy1623 glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D MGAS9429_Spy0518 kgdA; 4-Hydroxy-2-oxoglutarate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] C 00640 Propanoate metabolism [PATH:spk00640] D MGAS9429_Spy0095 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D MGAS9429_Spy0969 pta; phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D MGAS9429_Spy0869 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D MGAS9429_Spy1574 pfl; formate acetyltransferase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D MGAS9429_Spy1486 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D MGAS9429_Spy1490 accB; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D MGAS9429_Spy1488 accC; biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D MGAS9429_Spy1487 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D MGAS9429_Spy0991 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D MGAS9429_Spy1750 gldA; glycerol dehydrogenase K00005 gldA; glycerol dehydrogenase [EC:1.1.1.6] C 00650 Butanoate metabolism [PATH:spk00650] D MGAS9429_Spy0431 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0121 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy1339 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy1340 atoD1; acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D MGAS9429_Spy0122 atoD2; acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D MGAS9429_Spy1341 atoA; acetate CoA-transferase beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] D MGAS9429_Spy0123 acetate CoA-transferase beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] D MGAS9429_Spy0040 adh2; alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D MGAS9429_Spy0904 gabD; succinate-semialdehyde dehydrogenase (NADP+) K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D MGAS9429_Spy1574 pfl; formate acetyltransferase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D MGAS9429_Spy0743 mvaS1; hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D MGAS9429_Spy1342 D-beta-hydroxybutyrate dehydrogenase K00019 BDH1; 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30] D MGAS9429_Spy0953 Zn-dependent alcohol dehydrogenase K18369 adh2; alcohol dehydrogenase [EC:1.1.1.-] D MGAS9429_Spy0525 (R,R)-butanediol dehydrogenase K03366 butA; meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304] C 00660 C5-Branched dibasic acid metabolism C 00562 Inositol phosphate metabolism [PATH:spk00562] D MGAS9429_Spy1061 myo-inositol-1(or 4)-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D MGAS9429_Spy0363 NAD-dependent oxidoreductase K22230 iolU; scyllo-inositol 2-dehydrogenase (NADP+) [EC:1.1.1.-] D MGAS9429_Spy0499 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:spk00190] D MGAS9429_Spy0633 atpA; ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D MGAS9429_Spy0635 atpD; ATP synthase beta chain K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D MGAS9429_Spy0634 atpG; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D MGAS9429_Spy0632 atpH; ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D MGAS9429_Spy0636 atpC; ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D MGAS9429_Spy0630 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a D MGAS9429_Spy0631 atpF; ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b D MGAS9429_Spy0629 atpE; ATP synthase C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c D MGAS9429_Spy0133 ntpA; V-type sodium ATP synthase subunit A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] D MGAS9429_Spy0134 ntpB; V-type sodium ATP synthase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B D MGAS9429_Spy0131 ntpC; V-type sodium ATP synthase subunit C K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C D MGAS9429_Spy0135 ntpD; V-type sodium ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D D MGAS9429_Spy0130 ntpE; V-type sodium ATP synthase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E D MGAS9429_Spy0132 ntpF; V-type sodium ATP synthase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F D MGAS9429_Spy0127 hypothetical protein K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H D MGAS9429_Spy0128 ntpI; V-type sodium ATP synthase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I D MGAS9429_Spy0129 ntpK; V-type sodium ATP synthase subunit K K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K D MGAS9429_Spy0318 ppaC; inorganic pyrophosphatase K15986 ppaC; manganese-dependent inorganic pyrophosphatase [EC:3.6.1.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation in photosynthetic organisms C 00720 Carbon fixation pathways in prokaryotes C 00680 Methane metabolism [PATH:spk00680] D MGAS9429_Spy0984 glyA; serinehydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D MGAS9429_Spy0609 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D MGAS9429_Spy0495 ppc; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D MGAS9429_Spy1610 fba; fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D MGAS9429_Spy1093 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D MGAS9429_Spy0095 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D MGAS9429_Spy0969 pta; phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D MGAS9429_Spy1212 gpmA; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D MGAS9429_Spy0442 hypothetical protein K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34] C 00910 Nitrogen metabolism [PATH:spk00910] D MGAS9429_Spy1601 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MGAS9429_Spy1264 arcC; carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] D MGAS9429_Spy0202 carbonic anhydrase K01673 cynT; carbonic anhydrase [EC:4.2.1.1] C 00920 Sulfur metabolism [PATH:spk00920] D MGAS9429_Spy0600 phosphoesterase, DHH family protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] D MGAS9429_Spy1659 cysE; serineacetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D MGAS9429_Spy1324 cysM; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:spk00061] D MGAS9429_Spy1486 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D MGAS9429_Spy1490 accB; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D MGAS9429_Spy1488 accC; biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D MGAS9429_Spy1487 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D MGAS9429_Spy0021 acpP2; acyl-carrier protein K02078 acpP; acyl carrier protein D MGAS9429_Spy1495 acpP; acyl-carrier protein K02078 acpP; acyl carrier protein D MGAS9429_Spy1493 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D MGAS9429_Spy1496 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D MGAS9429_Spy1491 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D MGAS9429_Spy0362 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D MGAS9429_Spy1492 3-oxoacyl-(acyl-carrier protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D MGAS9429_Spy1489 fabZ; (3R)-hydroxyacyl-[acyl-carrier protein] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D MGAS9429_Spy1494 fabK; enoyl-(acyl-carrier protein) reductase (NADH) K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9] D MGAS9429_Spy1498 phaB; enoyl-CoA hydratase K18474 fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14] D MGAS9429_Spy0432 long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 00062 Fatty acid elongation C 00071 Fatty acid degradation [PATH:spk00071] D MGAS9429_Spy0431 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0121 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy1339 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0432 long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MGAS9429_Spy0040 adh2; alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D MGAS9429_Spy0041 adhA; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism [PATH:spk00561] D MGAS9429_Spy1623 glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D MGAS9429_Spy1750 gldA; glycerol dehydrogenase K00005 gldA; glycerol dehydrogenase [EC:1.1.1.6] D MGAS9429_Spy1379 glpK; glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D MGAS9429_Spy0020 plsX; fatty acid/phospholipid synthesis protein K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D MGAS9429_Spy0766 hypothetical membrane spanning protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D MGAS9429_Spy1197 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D MGAS9429_Spy0628 diacylglycerol kinase family protein K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107] D MGAS9429_Spy0425 1,2-diacylglycerol 3-glucosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D MGAS9429_Spy0424 glycosyltransferase K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208] D MGAS9429_Spy0677 sulfatase family protein K19005 ltaS; lipoteichoic acid synthase [EC:2.7.8.20] C 00564 Glycerophospholipid metabolism [PATH:spk00564] D MGAS9429_Spy0195 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] D MGAS9429_Spy1378 glpO; alpha-glycerophosphate oxidase K00105 E1.1.3.21; alpha-glycerophosphate oxidase [EC:1.1.3.21] D MGAS9429_Spy0766 hypothetical membrane spanning protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D MGAS9429_Spy1197 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D MGAS9429_Spy0628 diacylglycerol kinase family protein K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107] D MGAS9429_Spy0703 hypothetical protein K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] D MGAS9429_Spy1676 cdsA; phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41] D MGAS9429_Spy1858 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] D MGAS9429_Spy1565 phosphatidylglycerophosphatase B K01096 pgpB; phosphatidylglycerophosphatase B [EC:3.1.3.27 3.6.1.75 3.1.3.4 3.6.1.27] D MGAS9429_Spy1029 cardiolipin synthetase K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism D MGAS9429_Spy1298 lacZ; beta-galactosidase K01190 lacZ; beta-galactosidase [EC:3.2.1.23] C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:spk00230] D MGAS9429_Spy0366 ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D MGAS9429_Spy0752 deoB; phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7] D MGAS9429_Spy1041 pgmA; phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D MGAS9429_Spy0964 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D MGAS9429_Spy0018 prsA2; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D MGAS9429_Spy0024 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D MGAS9429_Spy0029 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D MGAS9429_Spy0026 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D MGAS9429_Spy0023 phosphoribosylformylglycinamidine synthase K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] D MGAS9429_Spy0025 purM; phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D MGAS9429_Spy0031 purK; phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] D MGAS9429_Spy0030 purE; phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D MGAS9429_Spy0022 phosphoribosylamidoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D MGAS9429_Spy0034 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D MGAS9429_Spy0027 phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D MGAS9429_Spy0786 apt; adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D MGAS9429_Spy0733 5'-nucleotidase K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5] D MGAS9429_Spy0754 punA; purine nucleoside phosphorylase K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1] D MGAS9429_Spy0755 deoD2; purine nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D MGAS9429_Spy0012 hypoxanthine-guanine phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] D MGAS9429_Spy1868 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D MGAS9429_Spy0890 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D MGAS9429_Spy0303 xanthosine triphosphate pyrophosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D MGAS9429_Spy0975 xpt; xanthine phosphoribosyltransferase K03816 xpt; xanthine phosphoribosyltransferase [EC:2.4.2.22] D MGAS9429_Spy1021 guaA; GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D MGAS9429_Spy0974 guaC; GMP reductase K00364 guaC; GMP reductase [EC:1.7.1.7] D MGAS9429_Spy1336 gmk; guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8] D MGAS9429_Spy1170 nrdE2; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D MGAS9429_Spy0352 nrdE1; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D MGAS9429_Spy1171 nrdF2; ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D MGAS9429_Spy0350 nrdF1; ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D MGAS9429_Spy1804 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D MGAS9429_Spy1689 relA; GTP pyrophosphokinase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D MGAS9429_Spy0966 GTP pyrophosphokinase-like protein K07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5] D MGAS9429_Spy0734 GTP pyrophosphokinase K07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5] D MGAS9429_Spy0138 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D MGAS9429_Spy0065 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D MGAS9429_Spy1264 arcC; carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] C 00240 Pyrimidine metabolism [PATH:spk00240] D MGAS9429_Spy0699 carB; carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D MGAS9429_Spy0697 carA; carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D MGAS9429_Spy0696 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D MGAS9429_Spy0765 pyrC; dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3] D MGAS9429_Spy1214 pyrD; dihydroorotate dehydrogenase K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1] D MGAS9429_Spy0760 pyrE; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D MGAS9429_Spy0759 pyrF; orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D MGAS9429_Spy0379 pyrH; uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D MGAS9429_Spy0890 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D MGAS9429_Spy1613 pyrG; CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2] D MGAS9429_Spy0673 cmk; cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D MGAS9429_Spy1163 udk; uridine kinase K00876 udk; uridine kinase [EC:2.7.1.48] D MGAS9429_Spy0733 5'-nucleotidase K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5] D MGAS9429_Spy1592 udp; uridine phosphorylase K00757 udp; uridine phosphorylase [EC:2.4.2.3] D MGAS9429_Spy0326 upp; uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9] D MGAS9429_Spy0694 pyrR; uracil phosphoribosyltransferase K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] D MGAS9429_Spy1046 cdd; cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5] D MGAS9429_Spy1804 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D MGAS9429_Spy1170 nrdE2; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D MGAS9429_Spy0352 nrdE1; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D MGAS9429_Spy1171 nrdF2; ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D MGAS9429_Spy0350 nrdF1; ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D MGAS9429_Spy1552 comEB; comE operon protein 2 K01493 comEB; dCMP deaminase [EC:3.5.4.12] D MGAS9429_Spy0332 tmk; thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D MGAS9429_Spy0200 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D MGAS9429_Spy0979 tdk2; thymidine kinase K00857 tdk; thymidine kinase [EC:2.7.1.21] D MGAS9429_Spy0744 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] D MGAS9429_Spy0970 short chain dehydrogenase K16066 ydfG; 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:spk00250] D MGAS9429_Spy1517 asnB; L-asparaginase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D MGAS9429_Spy1263 asnA; aspartate--ammonia ligase K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1] D MGAS9429_Spy0527 aspC; aspartate aminotransferase K22457 E2.6.1.14; asparagine---oxo-acid transaminase [EC:2.6.1.14] D MGAS9429_Spy1514 aspartate aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D MGAS9429_Spy0138 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D MGAS9429_Spy0034 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D MGAS9429_Spy0696 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D MGAS9429_Spy0904 gabD; succinate-semialdehyde dehydrogenase (NADP+) K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D MGAS9429_Spy1601 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MGAS9429_Spy0699 carB; carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D MGAS9429_Spy0697 carA; carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D MGAS9429_Spy1090 glmS; glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D MGAS9429_Spy0024 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:spk00260] D MGAS9429_Spy0984 glyA; serinehydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D MGAS9429_Spy1623 glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D MGAS9429_Spy1212 gpmA; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D MGAS9429_Spy0970 short chain dehydrogenase K16066 ydfG; 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-] D MGAS9429_Spy0869 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D MGAS9429_Spy1852 sdhB; L-serinedehydratase beta subunit K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D MGAS9429_Spy1853 sdhA; L-serinedehydratase alpha subunit K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] C 00270 Cysteine and methionine metabolism [PATH:spk00270] D MGAS9429_Spy1659 cysE; serineacetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D MGAS9429_Spy1324 cysM; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47] D MGAS9429_Spy0148 metB; cystathionine beta-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D MGAS9429_Spy1152 metK2; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D MGAS9429_Spy0444 metK1; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D MGAS9429_Spy0368 pfs; 5'-methylthioadenosine nucleosidase K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9] D MGAS9429_Spy1160 GAF domain-containing protein K08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14] D MGAS9429_Spy0915 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D MGAS9429_Spy1345 luxS; autoinducer-2 production protein luxS K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21] D MGAS9429_Spy0769 bcaT; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D MGAS9429_Spy0991 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D MGAS9429_Spy1852 sdhB; L-serinedehydratase beta subunit K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D MGAS9429_Spy1853 sdhA; L-serinedehydratase alpha subunit K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] C 00280 Valine, leucine and isoleucine degradation [PATH:spk00280] D MGAS9429_Spy0769 bcaT; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D MGAS9429_Spy0869 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D MGAS9429_Spy0431 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0121 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy1339 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0743 mvaS1; hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:spk00290] D MGAS9429_Spy0769 bcaT; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D MGAS9429_Spy1514 aspartate aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] C 00300 Lysine biosynthesis D MGAS9429_Spy1204 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] C 00310 Lysine degradation [PATH:spk00310] D MGAS9429_Spy0869 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D MGAS9429_Spy0431 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0121 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy1339 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0904 gabD; succinate-semialdehyde dehydrogenase (NADP+) K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D MGAS9429_Spy1340 atoD1; acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D MGAS9429_Spy0122 atoD2; acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D MGAS9429_Spy1341 atoA; acetate CoA-transferase beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] D MGAS9429_Spy0123 acetate CoA-transferase beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] C 00220 Arginine biosynthesis [PATH:spk00220] D MGAS9429_Spy1267 arcB; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D MGAS9429_Spy1269 arcA; arginine deiminase K01478 arcA; arginine deiminase [EC:3.5.3.6] D MGAS9429_Spy1601 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MGAS9429_Spy1264 arcC; carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] D MGAS9429_Spy1514 aspartate aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] C 00330 Arginine and proline metabolism [PATH:spk00330] D MGAS9429_Spy0761 amiC; amidase family protein K01426 E3.5.1.4; amidase [EC:3.5.1.4] D MGAS9429_Spy0097 proC; pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2] D MGAS9429_Spy1369 glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D MGAS9429_Spy1368 proA; gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] C 00340 Histidine metabolism [PATH:spk00340] D MGAS9429_Spy1788 hutH; histidine ammonia-lyase K01745 hutH; histidine ammonia-lyase [EC:4.3.1.3] D MGAS9429_Spy1782 hutU; urocanate hydratase K01712 hutU; urocanate hydratase [EC:4.2.1.49] D MGAS9429_Spy1780 hutI; imidazolonepropionase K01468 hutI; imidazolonepropionase [EC:3.5.2.7] D MGAS9429_Spy1789 hutG; formiminoglutamase K01479 hutG; formiminoglutamase [EC:3.5.3.8] D MGAS9429_Spy1783 glutamate formiminotransferase K00603 fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2] C 00350 Tyrosine metabolism [PATH:spk00350] D MGAS9429_Spy0040 adh2; alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D MGAS9429_Spy0041 adhA; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D MGAS9429_Spy0904 gabD; succinate-semialdehyde dehydrogenase (NADP+) K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] C 00360 Phenylalanine metabolism D MGAS9429_Spy0761 amiC; amidase family protein K01426 E3.5.1.4; amidase [EC:3.5.1.4] C 00380 Tryptophan metabolism [PATH:spk00380] D MGAS9429_Spy0869 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D MGAS9429_Spy0431 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0121 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy1339 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0761 amiC; amidase family protein K01426 E3.5.1.4; amidase [EC:3.5.1.4] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:spk00400] D MGAS9429_Spy1291 3-deoxy-7-phosphoheptulonate synthase K03856 AROA2; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D MGAS9429_Spy1292 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4] D MGAS9429_Spy0679 aroD; 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10] D MGAS9429_Spy0440 aroE2; shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] D MGAS9429_Spy1144 aroK; shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71] D MGAS9429_Spy1145 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D MGAS9429_Spy0680 aroF; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D MGAS9429_Spy1703 trpG; anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D MGAS9429_Spy0602 chorismate mutase K04516 AROA1; chorismate mutase [EC:5.4.99.5] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism C 00430 Taurine and hypotaurine metabolism [PATH:spk00430] D MGAS9429_Spy0969 pta; phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D MGAS9429_Spy0095 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:spk00450] D MGAS9429_Spy0148 metB; cystathionine beta-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D MGAS9429_Spy0246 nifS3; cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D MGAS9429_Spy1356 thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D MGAS9429_Spy0348 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism [PATH:spk00460] D MGAS9429_Spy1517 asnB; L-asparaginase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D MGAS9429_Spy1263 asnA; aspartate--ammonia ligase K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1] D MGAS9429_Spy0984 glyA; serinehydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism [PATH:spk00470] D MGAS9429_Spy1536 acpS; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D MGAS9429_Spy1205 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D MGAS9429_Spy1115 dltA; D-alanine-activating enzyme K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D MGAS9429_Spy1113 D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D MGAS9429_Spy0302 glr; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D MGAS9429_Spy1248 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] C 00480 Glutathione metabolism [PATH:spk00480] D MGAS9429_Spy1052 pepN; aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] D MGAS9429_Spy0775 glutathione S-transferase K00799 GST; glutathione S-transferase [EC:2.5.1.18] D MGAS9429_Spy0682 gor; glutathione reductase K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7] D MGAS9429_Spy0493 glutathione peroxidase K00432 gpx; glutathione peroxidase [EC:1.11.1.9] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation [PATH:spk00511] D MGAS9429_Spy1298 lacZ; beta-galactosidase K01190 lacZ; beta-galactosidase [EC:3.2.1.23] D MGAS9429_Spy1311 alpha-mannosidase K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24] C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis [PATH:spk00542] D MGAS9429_Spy0242 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:spk00541] D MGAS9429_Spy0194 hasC2; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D MGAS9429_Spy1864 hasC; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D MGAS9429_Spy0448 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D MGAS9429_Spy1863 hasB; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D MGAS9429_Spy0792 cpsFO; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D MGAS9429_Spy0794 cpsFQ; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D MGAS9429_Spy0793 cpsFP; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D MGAS9429_Spy0656 rmlD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] D MGAS9429_Spy1541 pmi; mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D MGAS9429_Spy0365 gcaD; glucosamine-1-phosphate acetyltransferase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] C 00550 Peptidoglycan biosynthesis [PATH:spk00550] D MGAS9429_Spy1151 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D MGAS9429_Spy0638 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D MGAS9429_Spy0944 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D MGAS9429_Spy0290 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D MGAS9429_Spy1248 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D MGAS9429_Spy1205 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D MGAS9429_Spy1204 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D MGAS9429_Spy0389 dgk; diacylglycerol kinase K00887 dgkA; undecaprenol kinase [EC:2.7.1.66] D MGAS9429_Spy1677 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D MGAS9429_Spy0240 bacA; bacitracin resistance protein (putative undecaprenol kinase) K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D MGAS9429_Spy0313 membrane-associated phospholipid phosphatase K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D MGAS9429_Spy1362 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D MGAS9429_Spy1247 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D MGAS9429_Spy1351 pbp1A; multimodular transpeptidase-transglycosylase PBP 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D MGAS9429_Spy1763 pbp2A; multimodular transpeptidase-transglycosylase PBP 2A K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D MGAS9429_Spy0250 dacA2; D-alanyl-D-alanine serine-type carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D MGAS9429_Spy0936 dacA1; D-alanyl-D-alanine serine-type carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D MGAS9429_Spy1504 D-alanyl-D-alanine metallocarboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D MGAS9429_Spy0324 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--lysine ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7] D MGAS9429_Spy0874 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K23393 murT; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13] D MGAS9429_Spy0873 CobB/CobQ-like glutamine amidotransferase domain K07009 gatD; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13] D MGAS9429_Spy1022 UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10] D MGAS9429_Spy0501 murM; UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10] D MGAS9429_Spy0500 factor essential for expression of methicillin resistance K12554 murN; alanine adding enzyme [EC:2.3.2.-] D MGAS9429_Spy0082 pbp1b; multimodular transpeptidase-transglycosylase PBP 1B K03693 pbp1b; penicillin-binding protein 1B D MGAS9429_Spy1363 division specific D,D-transpeptidase K12556 pbp2X; penicillin-binding protein 2X C 00552 Teichoic acid biosynthesis [PATH:spk00552] D MGAS9429_Spy0240 bacA; bacitracin resistance protein (putative undecaprenol kinase) K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D MGAS9429_Spy0313 membrane-associated phospholipid phosphatase K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D MGAS9429_Spy0242 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D MGAS9429_Spy1115 dltA; D-alanine-activating enzyme K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D MGAS9429_Spy1113 D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D MGAS9429_Spy1114 protein DltB K03739 dltB; membrane protein involved in D-alanine export D MGAS9429_Spy1112 dltD; protein dltD precursor K03740 dltD; D-alanine transfer protein D MGAS9429_Spy1476 lytR; transcriptional regulator, LytR family K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-] D MGAS9429_Spy1143 transcriptional regulator, LytR family K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-] D MGAS9429_Spy0677 sulfatase family protein K19005 ltaS; lipoteichoic acid synthase [EC:2.7.8.20] D MGAS9429_Spy0425 1,2-diacylglycerol 3-glucosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis [PATH:spk00543] D MGAS9429_Spy0242 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D MGAS9429_Spy1659 cysE; serineacetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:spk00730] D MGAS9429_Spy0685 nifS1; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D MGAS9429_Spy0963 nifS2; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D MGAS9429_Spy0686 thiI; thiamine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D MGAS9429_Spy0225 GTPase K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D MGAS9429_Spy0227 thiamin pyrophosphokinase K00949 thiN; thiamine pyrophosphokinase [EC:2.7.6.2] D MGAS9429_Spy0065 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism [PATH:spk00740] D MGAS9429_Spy1480 hydrolase (HAD superfamily) K21064 ycsE; 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.104] D MGAS9429_Spy1064 mreA; riboflavin kinase K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D MGAS9429_Spy0954 class B acid phosphatase K03788 aphA; acid phosphatase (class B) [EC:3.1.3.2] D MGAS9429_Spy0366 ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] C 00750 Vitamin B6 metabolism [PATH:spk00750] D MGAS9429_Spy1025 pyridoxine kinase K00868 pdxK; pyridoxine kinase [EC:2.7.1.35] D MGAS9429_Spy1619 thiD; phosphomethylpyrimidine kinase K00868 pdxK; pyridoxine kinase [EC:2.7.1.35] C 00760 Nicotinate and nicotinamide metabolism [PATH:spk00760] D MGAS9429_Spy0172 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D MGAS9429_Spy1354 nadE; nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21] D MGAS9429_Spy0754 punA; purine nucleoside phosphorylase K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1] D MGAS9429_Spy0755 deoD2; purine nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D MGAS9429_Spy0733 5'-nucleotidase K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5] D MGAS9429_Spy0262 nadD; nicotinate-nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] D MGAS9429_Spy1353 NH(3)-dependent NAD(+) synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5] D MGAS9429_Spy0141 nga; NAD glycohydrolase K18153 nga; NAD+ glycohydrolase [EC:3.2.2.5] D MGAS9429_Spy0967 ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] D MGAS9429_Spy0904 gabD; succinate-semialdehyde dehydrogenase (NADP+) K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] C 00770 Pantothenate and CoA biosynthesis [PATH:spk00770] D MGAS9429_Spy0714 apbA; ketopantoate reductase PanE/ApbA family protein K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169] D MGAS9429_Spy1048 coaA; pantothenate kinase K00867 coaA; type I pantothenate kinase [EC:2.7.1.33] D MGAS9429_Spy1038 dpfB; phosphopantothenate--cysteine ligase K21977 coaB; phosphopantothenate---cysteine ligase (CTP) [EC:6.3.2.5] D MGAS9429_Spy1039 dfp; phosphopantothenoylcysteine decarboxylase K01598 PPCDC; phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36] D MGAS9429_Spy1261 phosphopantetheine adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D MGAS9429_Spy0408 dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24] D MGAS9429_Spy1537 alr; holo-(acyl-carrier protein) synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7] D MGAS9429_Spy0769 bcaT; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] C 00780 Biotin metabolism [PATH:spk00780] D MGAS9429_Spy1491 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D MGAS9429_Spy0362 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D MGAS9429_Spy1492 3-oxoacyl-(acyl-carrier protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D MGAS9429_Spy1489 fabZ; (3R)-hydroxyacyl-[acyl-carrier protein] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D MGAS9429_Spy1154 birA; biotin operon repressor K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism [PATH:spk00785] D MGAS9429_Spy0872 lplB; lipoate-protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D MGAS9429_Spy1031 lplA; lipoate-protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D MGAS9429_Spy0869 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D MGAS9429_Spy0865 acoA; pyruvate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D MGAS9429_Spy0866 acoB; pyruvate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D MGAS9429_Spy0867 acoC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] C 00790 Folate biosynthesis [PATH:spk00790] D MGAS9429_Spy0940 folE; GTP cyclohydrolase I K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16] D MGAS9429_Spy0942 folQ; dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81] D MGAS9429_Spy0943 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D MGAS9429_Spy0941 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15] D MGAS9429_Spy0745 dyr; dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D MGAS9429_Spy0683 folC2; folylpolyglutamate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D MGAS9429_Spy0939 folC1; folylpolyglutamate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D MGAS9429_Spy1702 para-aminobenzoate synthetase component I K03342 pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38] C 00670 One carbon pool by folate [PATH:spk00670] D MGAS9429_Spy0745 dyr; dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D MGAS9429_Spy1030 fhs1; formate--tetrahydrofolate ligase K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] D MGAS9429_Spy1785 fhs2; formate--tetrahydrofolate ligase K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] D MGAS9429_Spy1228 folD; methylenetetrahydrofolate dehydrogenase (NADP+) K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D MGAS9429_Spy1784 formiminotetrahydrofolate cyclodeaminase K01500 fchA; methenyltetrahydrofolate cyclohydrolase [EC:3.5.4.9] D MGAS9429_Spy0984 glyA; serinehydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D MGAS9429_Spy0026 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D MGAS9429_Spy0027 phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D MGAS9429_Spy1783 glutamate formiminotransferase K00603 fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2] D MGAS9429_Spy1333 methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D MGAS9429_Spy0744 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] C 00830 Retinol metabolism C 00860 Porphyrin metabolism C 00130 Ubiquinone and other terpenoid-quinone biosynthesis B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:spk00900] D MGAS9429_Spy0431 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0121 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy1339 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0743 mvaS1; hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D MGAS9429_Spy0742 3-hydroxy-3-methylglutaryl-coenzyme A reductase K00054 mvaA; hydroxymethylglutaryl-CoA reductase [EC:1.1.1.88] D MGAS9429_Spy0737 mvaK1; mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36] D MGAS9429_Spy0739 mvaK2; phosphomevalonate kinase K00938 E2.7.4.2; phosphomevalonate kinase [EC:2.7.4.2] D MGAS9429_Spy0738 mvaD; diphosphomevalonate decarboxylase K01597 MVD; diphosphomevalonate decarboxylase [EC:4.1.1.33] D MGAS9429_Spy0740 isopentenyl-diphosphate delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2] D MGAS9429_Spy1225 fps; dimethylallyltransferase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29] D MGAS9429_Spy1677 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D MGAS9429_Spy1373 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis [PATH:spk00523] D MGAS9429_Spy0792 cpsFO; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D MGAS9429_Spy0794 cpsFQ; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D MGAS9429_Spy0793 cpsFP; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D MGAS9429_Spy0656 rmlD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics D MGAS9429_Spy0794 cpsFQ; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis C 00332 Carbapenem biosynthesis [PATH:spk00332] D MGAS9429_Spy1369 glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D MGAS9429_Spy1368 proA; gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] C 00261 Monobactam biosynthesis C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:spk00521] D MGAS9429_Spy1252 glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] D MGAS9429_Spy1041 pgmA; phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D MGAS9429_Spy1061 myo-inositol-1(or 4)-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D MGAS9429_Spy0792 cpsFO; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D MGAS9429_Spy0794 cpsFQ; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D MGAS9429_Spy0793 cpsFP; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D MGAS9429_Spy0656 rmlD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 00524 Neomycin, kanamycin and gentamicin biosynthesis D MGAS9429_Spy1252 glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2] C 00525 Acarbose and validamycin biosynthesis [PATH:spk00525] D MGAS9429_Spy0792 cpsFO; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D MGAS9429_Spy0794 cpsFQ; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] C 00401 Novobiocin biosynthesis C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D MGAS9429_Spy1703 trpG; anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis D MGAS9429_Spy1493 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D MGAS9429_Spy0362 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D MGAS9429_Spy1492 3-oxoacyl-(acyl-carrier protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics D MGAS9429_Spy0021 acpP2; acyl-carrier protein K02078 acpP; acyl carrier protein D MGAS9429_Spy1495 acpP; acyl-carrier protein K02078 acpP; acyl carrier protein C 00999 Biosynthesis of various plant secondary metabolites [PATH:spk00999] D MGAS9429_Spy1152 metK2; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D MGAS9429_Spy0444 metK1; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D MGAS9429_Spy0440 aroE2; shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation [PATH:spk00362] D MGAS9429_Spy1798 glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] D MGAS9429_Spy0978 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D MGAS9429_Spy0431 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0121 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy1339 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00627 Aminobenzoate degradation [PATH:spk00627] D MGAS9429_Spy0761 amiC; amidase family protein K01426 E3.5.1.4; amidase [EC:3.5.1.4] D MGAS9429_Spy0296 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D MGAS9429_Spy1340 atoD1; acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D MGAS9429_Spy0122 atoD2; acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D MGAS9429_Spy1341 atoA; acetate CoA-transferase beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] D MGAS9429_Spy0123 acetate CoA-transferase beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation [PATH:spk00625] D MGAS9429_Spy0041 adhA; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D MGAS9429_Spy0040 adh2; alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] C 00361 Chlorocyclohexane and chlorobenzene degradation D MGAS9429_Spy1798 glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] C 00623 Toluene degradation C 00622 Xylene degradation [PATH:spk00622] D MGAS9429_Spy1798 glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] D MGAS9429_Spy0978 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00633 Nitrotoluene degradation C 00642 Ethylbenzene degradation C 00643 Styrene degradation [PATH:spk00643] D MGAS9429_Spy0761 amiC; amidase family protein K01426 E3.5.1.4; amidase [EC:3.5.1.4] D MGAS9429_Spy1798 glyoxalase family protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation D MGAS9429_Spy0978 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00626 Naphthalene degradation [PATH:spk00626] D MGAS9429_Spy0041 adhA; alcohol dehydrogenase K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D MGAS9429_Spy0040 adh2; alcohol dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:spk03020] D MGAS9429_Spy0083 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D MGAS9429_Spy0084 DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D MGAS9429_Spy0085 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D MGAS9429_Spy0070 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D MGAS9429_Spy1335 DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D MGAS9429_Spy1614 rpoE; DNA-directed RNA polymerase delta chain K03048 rpoE; DNA-directed RNA polymerase subunit delta C 03022 Basal transcription factors C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:spk03010] D MGAS9429_Spy0771 SSU ribosomal protein S1P K02945 RP-S1; small subunit ribosomal protein S1 D MGAS9429_Spy1791 rpsB; SSU ribosomal protein S2P K02967 RP-S2; small subunit ribosomal protein S2 D MGAS9429_Spy0050 rpsC; SSU ribosomal protein S3P K02982 RP-S3; small subunit ribosomal protein S3 D MGAS9429_Spy1844 rpsD; SSU ribosomal protein S4P K02986 RP-S4; small subunit ribosomal protein S4 D MGAS9429_Spy0061 rpsE; SSU ribosomal protein S5P K02988 RP-S5; small subunit ribosomal protein S5 D MGAS9429_Spy1560 rpsF; SSU ribosomal protein S6P K02990 RP-S6; small subunit ribosomal protein S6 D MGAS9429_Spy0233 rpsG; SSU ribosomal protein S7P K02992 RP-S7; small subunit ribosomal protein S7 D MGAS9429_Spy0058 rpsH; SSU ribosomal protein S8P K02994 RP-S8; small subunit ribosomal protein S8 D MGAS9429_Spy1647 rpsI; SSU ribosomal protein S9P K02996 RP-S9; small subunit ribosomal protein S9 D MGAS9429_Spy0043 rpsJ; SSU ribosomal protein S10P K02946 RP-S10; small subunit ribosomal protein S10 D MGAS9429_Spy0069 rpsK; SSU ribosomal protein S11P K02948 RP-S11; small subunit ribosomal protein S11 D MGAS9429_Spy0232 rpsL; SSU ribosomal protein S12P K02950 RP-S12; small subunit ribosomal protein S12 D MGAS9429_Spy0068 rpsM; SSU ribosomal protein S13P K02952 RP-S13; small subunit ribosomal protein S13 D MGAS9429_Spy0057 rpsN; SSU ribosomal protein S14P K02954 RP-S14; small subunit ribosomal protein S14 D MGAS9429_Spy1595 rpsN2; SSU ribosomal protein S14P K02954 RP-S14; small subunit ribosomal protein S14 D MGAS9429_Spy1667 SSU ribosomal protein S15P K02956 RP-S15; small subunit ribosomal protein S15 D MGAS9429_Spy0704 rpsP; SSU ribosomal protein S16P K02959 RP-S16; small subunit ribosomal protein S16 D MGAS9429_Spy0053 rpsQ; SSU ribosomal protein S17P K02961 RP-S17; small subunit ribosomal protein S17 D MGAS9429_Spy1558 rpsR; SSU ribosomal protein S18P K02963 RP-S18; small subunit ribosomal protein S18 D MGAS9429_Spy0048 rpsS; SSU ribosomal protein S19P K02965 RP-S19; small subunit ribosomal protein S19 D MGAS9429_Spy1049 rpsT; SSU ribosomal protein S20P K02968 RP-S20; small subunit ribosomal protein S20 D MGAS9429_Spy0651 SSU ribosomal protein S21P K02970 RP-S21; small subunit ribosomal protein S21 D MGAS9429_Spy0378 rplA; LSU ribosomal protein L1P K02863 RP-L1; large subunit ribosomal protein L1 D MGAS9429_Spy0047 rplB; LSU ribosomal protein L2P K02886 RP-L2; large subunit ribosomal protein L2 D MGAS9429_Spy0044 rplC; LSU ribosomal protein L3P K02906 RP-L3; large subunit ribosomal protein L3 D MGAS9429_Spy0045 rplD; LSU ribosomal protein L1E (L4P) K02926 RP-L4; large subunit ribosomal protein L4 D MGAS9429_Spy0056 rplE; LSU ribosomal protein L5P K02931 RP-L5; large subunit ribosomal protein L5 D MGAS9429_Spy0059 rplF; LSU ribosomal protein L6P K02933 RP-L6; large subunit ribosomal protein L6 D MGAS9429_Spy0910 rplL; LSU ribosomal protein L12P (L7/L12) K02935 RP-L7; large subunit ribosomal protein L7/L12 D MGAS9429_Spy1847 rplI; LSU ribosomal protein L9P K02939 RP-L9; large subunit ribosomal protein L9 D MGAS9429_Spy0909 rplJ; LSU ribosomal protein L10P K02864 RP-L10; large subunit ribosomal protein L10 D MGAS9429_Spy0377 rplK; LSU ribosomal protein L11P K02867 RP-L11; large subunit ribosomal protein L11 D MGAS9429_Spy1648 rplM; LSU ribosomal protein L13P K02871 RP-L13; large subunit ribosomal protein L13 D MGAS9429_Spy0054 rplN; LSU ribosomal protein L14P K02874 RP-L14; large subunit ribosomal protein L14 D MGAS9429_Spy0063 rplO; LSU ribosomal protein L15P K02876 RP-L15; large subunit ribosomal protein L15 D MGAS9429_Spy0051 rplP; LSU ribosomal protein L16P K02878 RP-L16; large subunit ribosomal protein L16 D MGAS9429_Spy0071 rplQ; LSU ribosomal protein L17P K02879 RP-L17; large subunit ribosomal protein L17 D MGAS9429_Spy0060 rplR; LSU ribosomal protein L18P K02881 RP-L18; large subunit ribosomal protein L18 D MGAS9429_Spy0604 rplS; LSU ribosomal protein L19P K02884 RP-L19; large subunit ribosomal protein L19 D MGAS9429_Spy0676 rplT; LSU ribosomal protein L20P K02887 RP-L20; large subunit ribosomal protein L20 D MGAS9429_Spy0688 rplU; LSU ribosomal protein L21P K02888 RP-L21; large subunit ribosomal protein L21 D MGAS9429_Spy0049 rplV; LSU ribosomal protein L22P K02890 RP-L22; large subunit ribosomal protein L22 D MGAS9429_Spy0046 rplW; LSU ribosomal protein L23P K02892 RP-L23; large subunit ribosomal protein L23 D MGAS9429_Spy0055 rplX; LSU ribosomal protein L24P K02895 RP-L24; large subunit ribosomal protein L24 D MGAS9429_Spy0690 rpmA; LSU ribosomal protein L27P K02899 RP-L27; large subunit ribosomal protein L27 D MGAS9429_Spy1609 rpmB; LSU ribosomal protein L28P K02902 RP-L28; large subunit ribosomal protein L28 D MGAS9429_Spy0052 rpmC; LSU ribosomal protein L29P K02904 RP-L29; large subunit ribosomal protein L29 D MGAS9429_Spy0062 rpmD; LSU ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30 D MGAS9429_Spy0599 rpmE; LSU ribosomal protein L31P K02909 RP-L31; large subunit ribosomal protein L31 D MGAS9429_Spy1826 rpmF; LSU ribosomal protein L32P K02911 RP-L32; large subunit ribosomal protein L32 D MGAS9429_Spy0411 LSU ribosomal protein L33P K02913 RP-L33; large subunit ribosomal protein L33 D MGAS9429_Spy1762 LSU ribosomal protein L33P K02913 RP-L33; large subunit ribosomal protein L33 D MGAS9429_Spy1827 rpmG; LSU ribosomal protein L33P K02913 RP-L33; large subunit ribosomal protein L33 D MGAS9429_Spy0212 rpmH; LSU ribosomal protein L34P K02914 RP-L34; large subunit ribosomal protein L34 D MGAS9429_Spy0675 rpl36; LSU ribosomal protein L35P K02916 RP-L35; large subunit ribosomal protein L35 D MGAS9429_Spy0067 rpmJ; LSU ribosomal protein L36P K02919 RP-L36; large subunit ribosomal protein L36 D MGAS9429_SpyR0010 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0004 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0007 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0015 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0018 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0001 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0002 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0011 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0005 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0008 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0017 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0014 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0003 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0009 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0006 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0012 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0016 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0013 5S RNA K01985 5SrRNA; 5S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:spk00970] D MGAS9429_SpyR0010 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0004 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0007 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyT0001 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D MGAS9429_SpyT0029 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D MGAS9429_SpyT0011 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D MGAS9429_SpyT0057 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D MGAS9429_SpyT0062 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D MGAS9429_SpyT0042 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D MGAS9429_SpyT0048 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D MGAS9429_SpyT0067 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D MGAS9429_SpyT0045 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D MGAS9429_SpyT0044 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D MGAS9429_SpyT0009 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D MGAS9429_SpyT0019 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D MGAS9429_SpyT0060 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D MGAS9429_SpyT0065 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D MGAS9429_SpyT0061 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D MGAS9429_SpyT0043 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D MGAS9429_SpyT0003 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D MGAS9429_SpyT0055 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D MGAS9429_SpyT0013 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D MGAS9429_SpyT0064 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D MGAS9429_SpyT0047 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D MGAS9429_SpyT0040 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D MGAS9429_SpyT0033 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D MGAS9429_SpyT0066 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D MGAS9429_SpyT0050 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D MGAS9429_SpyT0026 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D MGAS9429_SpyT0031 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D MGAS9429_SpyT0007 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D MGAS9429_SpyT0017 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D MGAS9429_SpyT0039 tRNA-His K14226 tRNA-His; tRNA His D MGAS9429_SpyT0027 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D MGAS9429_SpyT0051 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D MGAS9429_SpyT0032 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D MGAS9429_SpyT0008 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D MGAS9429_SpyT0018 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D MGAS9429_SpyT0041 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D MGAS9429_SpyT0005 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D MGAS9429_SpyT0053 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D MGAS9429_SpyT0015 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D MGAS9429_SpyT0059 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D MGAS9429_SpyT0004 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D MGAS9429_SpyT0054 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D MGAS9429_SpyT0014 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D MGAS9429_SpyT0063 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D MGAS9429_SpyT0021 tRNA-Met K14230 tRNA-Met; tRNA Met D MGAS9429_SpyT0022 tRNA-Met K14230 tRNA-Met; tRNA Met D MGAS9429_SpyT0024 tRNA-Met K14230 tRNA-Met; tRNA Met D MGAS9429_SpyT0035 tRNA-Met K14230 tRNA-Met; tRNA Met D MGAS9429_SpyT0025 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D MGAS9429_SpyT0036 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D MGAS9429_SpyT0010 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D MGAS9429_SpyT0020 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D MGAS9429_SpyT0023 pseudogene K14233 tRNA-Ser; tRNA Ser D MGAS9429_SpyT0034 pseudogene K14233 tRNA-Ser; tRNA Ser D MGAS9429_SpyT0058 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D MGAS9429_SpyT0028 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D MGAS9429_SpyT0049 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D MGAS9429_SpyT0006 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D MGAS9429_SpyT0016 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D MGAS9429_SpyT0052 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D MGAS9429_SpyT0038 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D MGAS9429_SpyT0037 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D MGAS9429_SpyT0046 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D MGAS9429_SpyT0002 tRNA-Val K14237 tRNA-Val; tRNA Val D MGAS9429_SpyT0056 tRNA-Val K14237 tRNA-Val; tRNA Val D MGAS9429_SpyT0030 tRNA-Val K14237 tRNA-Val; tRNA Val D MGAS9429_SpyT0012 tRNA-Val K14237 tRNA-Val; tRNA Val D MGAS9429_Spy0204 gltX; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D MGAS9429_Spy1509 gatA; aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D MGAS9429_Spy1508 gatB; aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D MGAS9429_Spy1510 gatC; glutamyl-tRNA(Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D MGAS9429_Spy1179 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D MGAS9429_Spy1824 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D MGAS9429_Spy0528 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D MGAS9429_Spy1383 glyQ; glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D MGAS9429_Spy1382 glyS; glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D MGAS9429_Spy0426 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D MGAS9429_Spy1485 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D MGAS9429_Spy1656 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D MGAS9429_Spy0348 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D MGAS9429_Spy1333 methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D MGAS9429_Spy1286 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D MGAS9429_Spy0149 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D MGAS9429_Spy1238 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D MGAS9429_Spy0485 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D MGAS9429_Spy1819 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D MGAS9429_Spy1674 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D MGAS9429_Spy1825 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D MGAS9429_Spy0641 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D MGAS9429_Spy0642 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D MGAS9429_Spy0081 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D MGAS9429_Spy1869 trsA; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:spk03060] D MGAS9429_Spy0064 secY; protein translocase subunit K03076 secY; preprotein translocase subunit SecY D MGAS9429_Spy1761 secE; protein translocase subunit K03073 secE; preprotein translocase subunit SecE D MGAS9429_Spy0412 secG; protein translocase subunit K03075 secG; preprotein translocase subunit SecG D MGAS9429_Spy1679 yajC; protein translocase subunit K03210 yajC; preprotein translocase subunit YajC D MGAS9429_Spy0209 60 kDa inner membrane protein YIDC K03217 yidC; YidC/Oxa1 family membrane protein insertase D MGAS9429_Spy0295 60 kDa inner membrane protein YIDC K03217 yidC; YidC/Oxa1 family membrane protein insertase D MGAS9429_Spy1538 secA; protein translocase subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D MGAS9429_Spy1017 ffh; signal recognition particle subunit FFH/SRP54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D MGAS9429_Spy0464 ftsY; cell division protein K03110 ftsY; fused signal recognition particle receptor D MGAS9429_Spy1091 sipC; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D MGAS9429_Spy0112 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D MGAS9429_Spy1570 spi; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D MGAS9429_Spy0692 lsp; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:spk04122] D MGAS9429_Spy0685 nifS1; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D MGAS9429_Spy0963 nifS2; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D MGAS9429_Spy1851 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D MGAS9429_Spy0686 thiI; thiamine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] C 03050 Proteasome C 03018 RNA degradation [PATH:spk03018] D MGAS9429_Spy0609 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D MGAS9429_Spy1661 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D MGAS9429_Spy0413 exoribonuclease II K12573 rnr; ribonuclease R [EC:3.1.13.1] D MGAS9429_Spy1200 deaD; ATP-dependent RNA helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D MGAS9429_Spy1337 hydrolase (HAD superfamily) K18682 rny; ribonucrease Y [EC:3.1.-.-] D MGAS9429_Spy1600 Zn-dependent hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-] D MGAS9429_Spy0861 Zn-dependent hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-] D MGAS9429_Spy1093 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D MGAS9429_Spy1500 dnaK; chaperone protein K04043 dnaK; molecular chaperone DnaK D MGAS9429_Spy1771 groEL; 60 kDa chaperonin GROEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] B B 09124 Replication and repair C 03030 DNA replication [PATH:spk03030] D MGAS9429_Spy1587 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D MGAS9429_Spy1094 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D MGAS9429_Spy1673 polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D MGAS9429_Spy1159 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D MGAS9429_Spy0333 dnaX; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D MGAS9429_Spy1193 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D MGAS9429_Spy0002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D MGAS9429_Spy1846 holB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D MGAS9429_Spy0653 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D MGAS9429_Spy0103 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D MGAS9429_Spy1559 ssb3; single strand binding protein K03111 ssb; single-strand DNA-binding protein D MGAS9429_Spy1001 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D MGAS9429_Spy1569 ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4] D MGAS9429_Spy0161 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D MGAS9429_Spy0627 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03410 Base excision repair [PATH:spk03410] D MGAS9429_Spy0788 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D MGAS9429_Spy0764 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D MGAS9429_Spy1562 mutY; A/G-specific adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D MGAS9429_Spy0407 fpg; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D MGAS9429_Spy1812 tag; DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D MGAS9429_Spy0342 exoA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D MGAS9429_Spy0161 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D MGAS9429_Spy0784 single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D MGAS9429_Spy0785 recJ; single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D MGAS9429_Spy0627 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03420 Nucleotide excision repair [PATH:spk03420] D MGAS9429_Spy0006 trcF; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D MGAS9429_Spy1554 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A D MGAS9429_Spy1117 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B D MGAS9429_Spy0905 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C D MGAS9429_Spy1080 pcrA; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D MGAS9429_Spy0161 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D MGAS9429_Spy0627 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03430 Mismatch repair [PATH:spk03430] D MGAS9429_Spy1816 mutS; DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS D MGAS9429_Spy1566 mutS2; DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2 D MGAS9429_Spy1815 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL D MGAS9429_Spy1080 pcrA; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D MGAS9429_Spy1227 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D MGAS9429_Spy1226 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D MGAS9429_Spy0784 single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D MGAS9429_Spy0785 recJ; single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D MGAS9429_Spy0103 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D MGAS9429_Spy1559 ssb3; single strand binding protein K03111 ssb; single-strand DNA-binding protein D MGAS9429_Spy1094 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D MGAS9429_Spy1673 polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D MGAS9429_Spy0002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D MGAS9429_Spy1159 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D MGAS9429_Spy1193 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D MGAS9429_Spy0333 dnaX; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D MGAS9429_Spy1587 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D MGAS9429_Spy0627 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03440 Homologous recombination [PATH:spk03440] D MGAS9429_Spy0784 single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D MGAS9429_Spy0785 recJ; single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D MGAS9429_Spy0103 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D MGAS9429_Spy1559 ssb3; single strand binding protein K03111 ssb; single-strand DNA-binding protein D MGAS9429_Spy1866 recF; DNA replication and repair protein K03629 recF; DNA replication and repair protein RecF D MGAS9429_Spy0019 recO; DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O) D MGAS9429_Spy1206 recR; recombination protein K06187 recR; recombination protein RecR D MGAS9429_Spy1810 recA; RecA protein K03553 recA; recombination protein RecA D MGAS9429_Spy0161 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D MGAS9429_Spy1813 ruvA; holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA D MGAS9429_Spy0036 ruvB; holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D MGAS9429_Spy1521 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D MGAS9429_Spy1571 recD; exodeoxyribonuclease V alpha chain K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D MGAS9429_Spy1094 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D MGAS9429_Spy1673 polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D MGAS9429_Spy0002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D MGAS9429_Spy1159 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D MGAS9429_Spy1193 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D MGAS9429_Spy0333 dnaX; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D MGAS9429_Spy1587 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D MGAS9429_Spy1334 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] C 03450 Non-homologous end-joining C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 [PATH:spk03250] D MGAS9429_Spy0374 peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus and Lyssavirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:spk02010] D MGAS9429_Spy0903 iron(III)-binding protein K02012 afuA; iron(III) transport system substrate-binding protein D MGAS9429_Spy0948 spermidine/putrescine-binding protein K11069 potD; spermidine/putrescine transport system substrate-binding protein D MGAS9429_Spy0947 potC; spermidine/putrescine transport system permease protein K11070 potC; spermidine/putrescine transport system permease protein D MGAS9429_Spy0946 potB; spermidine/putrescine transport system permease protein K11071 potB; spermidine/putrescine transport system permease protein D MGAS9429_Spy0945 potA; spermidine/putrescine transport ATP-binding protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] D MGAS9429_Spy0160 opuABC; glycine betaine-binding protein K02001 proW; glycine betaine/proline transport system permease protein D MGAS9429_Spy0159 opuAA; glycine betaine transport ATP-binding protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9] D MGAS9429_Spy0973 glycine betaine transport system permease protein K05845 opuC; osmoprotectant transport system substrate-binding protein D MGAS9429_Spy0972 proV; glycine betaine transport ATP-binding protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] D MGAS9429_Spy1685 msmK; multiple sugar transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D MGAS9429_Spy1104 malX; maltose/maltodextrin-binding protein K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein D MGAS9429_Spy1105 malC; maltodextrin transport system permease protein K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D MGAS9429_Spy1106 malD; maltose transport system permease protein K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D MGAS9429_Spy1302 sugar-binding protein K17318 lplA; putative aldouronate transport system substrate-binding protein D MGAS9429_Spy1304 sugar transport system permease protein K17319 lplB; putative aldouronate transport system permease protein D MGAS9429_Spy1303 sugar transport system permease protein K17320 lplC; putative aldouronate transport system permease protein D MGAS9429_Spy0139 nucleoside-binding protein K07335 bmpA; basic membrane protein A and related proteins D MGAS9429_Spy1045 nucleoside-binding protein K07335 bmpA; basic membrane protein A and related proteins D MGAS9429_Spy1043 nucleoside transport system permease protein K23535 nupB; general nucleoside transport system permease protein D MGAS9429_Spy1042 nucleoside transport system permease protein K23536 nupC; general nucleoside transport system permease protein D MGAS9429_Spy1044 nucleoside transport ATP-binding protein K23537 nupA; general nucleoside transport system ATP-binding protein D MGAS9429_Spy1059 pstS; phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D MGAS9429_Spy1058 pstC; phosphate transport system permease protein K02037 pstC; phosphate transport system permease protein D MGAS9429_Spy1057 pstA; phosphate transport system permease protein K02038 pstA; phosphate transport system permease protein D MGAS9429_Spy1055 pstB; phosphate transport ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D MGAS9429_Spy1056 pstB2; phosphate transport ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D MGAS9429_Spy1118 glnH; glutamine-binding protein K10036 glnH; glutamine transport system substrate-binding protein D MGAS9429_Spy1119 glnQ2; glutamine transport ATP-binding protein K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1] D MGAS9429_Spy0762 cystine-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D MGAS9429_Spy0269 ABC transporter substrate-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D MGAS9429_Spy0763 cystine transport system permease protein K10009 tcyB; L-cystine transport system permease protein D MGAS9429_Spy1359 amino acid ABC transporter permease protein K10009 tcyB; L-cystine transport system permease protein D MGAS9429_Spy1358 amino acid transport ATP-binding protein K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1] D MGAS9429_Spy0650 arginine-binding protein K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein D MGAS9429_Spy1233 artQ; arginine transport system permease protein K17077 artQ; arginine/lysine/histidine transport system permease protein D MGAS9429_Spy1232 artP; arginine transport ATP-binding protein K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1] D MGAS9429_Spy0238 ABC transporter amino acid-binding protein K17073 lysX1; putative lysine transport system substrate-binding protein D MGAS9429_Spy0237 amino acid transport ATP-binding protein K17076 lysY; putative lysine transport system ATP-binding protein D MGAS9429_Spy0270 ABC transporter substrate-binding protein K02073 metQ; D-methionine transport system substrate-binding protein D MGAS9429_Spy0272 ABC transporter permease protein K02072 metI; D-methionine transport system permease protein D MGAS9429_Spy0271 ABC transporter ATP-binding protein K02071 metN; D-methionine transport system ATP-binding protein D MGAS9429_Spy0251 oppA; oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein D MGAS9429_Spy0252 oppB; oligopeptide transport system permease protein K15581 oppB; oligopeptide transport system permease protein D MGAS9429_Spy0253 oppC; oligopeptide transport system permease protein K15582 oppC; oligopeptide transport system permease protein D MGAS9429_Spy0254 oppD; oligopeptide transport ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein D MGAS9429_Spy0255 oppF; oligopeptide transport ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein D MGAS9429_Spy0596 high-affinity zinc uptake system protein znuA precursor K09815 znuA; zinc transport system substrate-binding protein D MGAS9429_Spy1717 lmb; laminin-binding surface protein K09815 znuA; zinc transport system substrate-binding protein D MGAS9429_Spy0079 adcB; high-affinity zinc uptake system membrane protein K09816 znuB; zinc transport system permease protein D MGAS9429_Spy0078 adcC; high-affinity zinc uptake system ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D MGAS9429_Spy0371 mtsA; manganese-binding protein K11704 mtsA; iron/zinc/manganese/copper transport system substrate-binding protein D MGAS9429_Spy0373 mtsC; manganese transport system membrane protein K11705 mtsC; iron/zinc/manganese/copper transport system permease protein D MGAS9429_Spy0372 mtsB; manganese transport system ATP-binding protein K11706 mtsB; iron/zinc/manganese/copper transport system ATP-binding protein D MGAS9429_Spy0179 BioY protein K03523 bioY; biotin transport system substrate-specific component D MGAS9429_Spy1855 cbiQ; hyaluronan ABC exporter permease protein K16785 ecfT; energy-coupling factor transport system permease protein D MGAS9429_Spy1525 cobalt transport protein K16785 ecfT; energy-coupling factor transport system permease protein D MGAS9429_Spy1857 cbiO1; hyaluronan ABC exporter ATP-binding protein K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D MGAS9429_Spy1856 cbiO2; hyaluronan ABC exporter ATP-binding protein K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D MGAS9429_Spy0928 srtE; lantibiotic transport permease protein K20491 nisE; lantibiotic transport system permease protein D MGAS9429_Spy0929 srtG; lantibiotic transport permease protein K20492 nisG; lantibiotic transport system permease protein D MGAS9429_Spy0927 srtF; lantibiotic transport ATP-binding protein K20490 nisF; lantibiotic transport system ATP-binding protein D MGAS9429_Spy0523 ftsX; cell division protein K09811 ftsX; cell division transport system permease protein D MGAS9429_Spy0522 ftsE; cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein D MGAS9429_Spy0197 multidrug resistance ABC transporter ATP-binding and permease protein K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump D MGAS9429_Spy0198 multidrug/protein/lipid ABC transporter family, ATP-binding and permease protein K18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump D MGAS9429_Spy0988 multidrug resistance ABC transporter ATP-binding and permease protein K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump D MGAS9429_Spy0989 multidrug resistance ABC transporter ATP-binding and permease protein K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump C 02060 Phosphotransferase system (PTS) [PATH:spk02060] D MGAS9429_Spy1167 pstI; phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D MGAS9429_Spy1168 ptsH; phosphocarrier protein HPr K02784 ptsH; phosphocarrier protein HPr D MGAS9429_Spy1693 PTS system, glucose-specific IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208] D MGAS9429_Spy1546 scrA; PTS system, sucrose-specific IIABC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D MGAS9429_Spy0467 PTS system, beta-glucoside-specific IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D MGAS9429_Spy1795 PTS system, trehalose-specific IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D MGAS9429_Spy1637 lacF; PTS system, lactose-specific IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D MGAS9429_Spy1636 lacE; PTS system, lactose-specific IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D MGAS9429_Spy1756 PTS system, cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D MGAS9429_Spy1124 PTS system, cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D MGAS9429_Spy1125 PTS system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D MGAS9429_Spy1755 PTS system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D MGAS9429_Spy1754 PTS system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component D MGAS9429_Spy1122 PTS system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component D MGAS9429_Spy0897 PTS system, mannose/fructose family IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D MGAS9429_Spy1481 manL; PTS system, mannose-specific IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D MGAS9429_Spy0899 ptsC; PTS system, mannose/fructose family IIC component K02795 manY; mannose PTS system EIIC component D MGAS9429_Spy1482 manM; PTS system, mannose-specific IIC component K02795 manY; mannose PTS system EIIC component D MGAS9429_Spy0900 ptsD; PTS system, mannose/fructose family IID component K02796 manZ; mannose PTS system EIID component D MGAS9429_Spy1483 manN; PTS system, mannose-specific IID component K02796 manZ; mannose PTS system EIID component D MGAS9429_Spy0898 ptsB; PTS system, mannose/fructose family IIB component K19507 gfrB; fructoselysine/glucoselysine PTS system EIIB component [EC:2.7.1.-] D MGAS9429_Spy0514 PTS system, N-acetylgalactosamine-specific IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-] D MGAS9429_Spy0512 agaV; PTS system, N-acetylgalactosamine-specific IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-] D MGAS9429_Spy0511 PTS system, N-acetylgalactosamine-specific IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component D MGAS9429_Spy0510 agaD; PTS system, N-acetylgalactosamine-specific IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component D MGAS9429_Spy1404 PTS system, galactose-specific IIA component K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204] D MGAS9429_Spy1403 PTS system, galactose-specific IIB component K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204] D MGAS9429_Spy1402 PTS system, galactose-specific IIC component K20114 gatC; galactose PTS system EIIC component D MGAS9429_Spy0152 PTS system, 3-keto-L-gulonate specific IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D MGAS9429_Spy1665 transcription antiterminator, BglG family K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D MGAS9429_Spy0151 PTS system, 3-keto-L-gulonate specific IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D MGAS9429_Spy1664 PTS system, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D MGAS9429_Spy0150 PTS system, 3-keto-L-gulonate specific IIC component K03475 ulaA; ascorbate PTS system EIIC component D MGAS9429_Spy1663 putative transport protein sgaT K03475 ulaA; ascorbate PTS system EIIC component D MGAS9429_Spy0717 fruA; PTS system, fructose-specific IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D MGAS9429_Spy0716 fruB; 1-phosphofructokinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56] C 03070 Bacterial secretion system [PATH:spk03070] D MGAS9429_Spy1761 secE; protein translocase subunit K03073 secE; preprotein translocase subunit SecE D MGAS9429_Spy0412 secG; protein translocase subunit K03075 secG; preprotein translocase subunit SecG D MGAS9429_Spy0064 secY; protein translocase subunit K03076 secY; preprotein translocase subunit SecY D MGAS9429_Spy1679 yajC; protein translocase subunit K03210 yajC; preprotein translocase subunit YajC D MGAS9429_Spy0209 60 kDa inner membrane protein YIDC K03217 yidC; YidC/Oxa1 family membrane protein insertase D MGAS9429_Spy0295 60 kDa inner membrane protein YIDC K03217 yidC; YidC/Oxa1 family membrane protein insertase D MGAS9429_Spy1538 secA; protein translocase subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D MGAS9429_Spy0464 ftsY; cell division protein K03110 ftsY; fused signal recognition particle receptor D MGAS9429_Spy1017 ffh; signal recognition particle subunit FFH/SRP54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] B B 09132 Signal transduction C 02020 Two-component system [PATH:spk02020] D MGAS9429_Spy1059 pstS; phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D MGAS9429_Spy1877 htrA; endopeptidase K04771 degP; serine protease Do [EC:3.4.21.107] D MGAS9429_Spy0435 vicK; two-component sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] D MGAS9429_Spy0434 vicR; two-component response regulator K07668 vicR; two-component system, OmpR family, response regulator VicR D MGAS9429_Spy0001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein D MGAS9429_Spy1115 dltA; D-alanine-activating enzyme K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D MGAS9429_Spy1114 protein DltB K03739 dltB; membrane protein involved in D-alanine export D MGAS9429_Spy1113 D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D MGAS9429_Spy1112 dltD; protein dltD precursor K03740 dltD; D-alanine transfer protein D MGAS9429_Spy1050 ciaH; sensor protein K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D MGAS9429_Spy1051 ciaR; transcriptional regulatory protein K14983 ciaR; two-component system, OmpR family, response regulator CiaR D MGAS9429_Spy1504 D-alanyl-D-alanine metallocarboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D MGAS9429_Spy0283 covS; transmembrane histidine kinase K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3] D MGAS9429_Spy0282 covR; response regulator K18941 arlR; two-component system, OmpR family, response regulator ArlR D MGAS9429_Spy1729 ihk; two-component system histidine kinase K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3] D MGAS9429_Spy1730 irr; two-component response regulator K18987 irr; two-component system, OmpR family, response regulator Irr D MGAS9429_Spy0921 srtK; lantibiotic biosynthesis sensor protein K20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3] D MGAS9429_Spy0920 srtR; lantibiotic biosynthesis two-component response regulator K20488 nisR; two-component system, OmpR family, lantibiotic biosynthesis response regulator NisR/SpaR D MGAS9429_Spy0926 serine/threonine dehydratase K20483 nisB; lantibiotic biosynthesis protein D MGAS9429_Spy0924 lanthionine synthetase K20484 nisC; lantibiotic biosynthesis protein D MGAS9429_Spy0923 srtT; lantibiotic transport permease protein K20485 nisT; ATP-binding cassette, subfamily B, bacterial NisT/SpaT D MGAS9429_Spy0927 srtF; lantibiotic transport ATP-binding protein K20490 nisF; lantibiotic transport system ATP-binding protein D MGAS9429_Spy0928 srtE; lantibiotic transport permease protein K20491 nisE; lantibiotic transport system permease protein D MGAS9429_Spy0929 srtG; lantibiotic transport permease protein K20492 nisG; lantibiotic transport system permease protein D MGAS9429_Spy1012 citC; [citrate [pro-3S]-lyase] ligase K01910 citC; [citrate (pro-3S)-lyase] ligase [EC:6.2.1.22] D MGAS9429_Spy0952 NAD-dependent malic enzyme K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D MGAS9429_Spy0951 malP; malate-sodium symport K11616 maeN; malate:Na+ symporter D MGAS9429_Spy1312 rocA; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D MGAS9429_Spy0205 fasB; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D MGAS9429_Spy0206 fasC; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D MGAS9429_Spy0207 fasA; response regulator K07707 agrA; two-component system, LytTR family, response regulator AgrA D MGAS9429_Spy0258 comX1-1; competence-specific sigma factor K12296 comX1_2; competence protein ComX D MGAS9429_Spy1621 comX2; competence-specific sigma factor K12296 comX1_2; competence protein ComX D MGAS9429_Spy0010 beta-lactamase K01467 ampC; beta-lactamase class C [EC:3.5.2.6] D MGAS9429_Spy1328 yvqE; two-component sensor protein K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3] D MGAS9429_Spy1327 yvqC; two-component response regulator K11618 liaR; two-component system, NarL family, response regulator LiaR D MGAS9429_Spy1629 sensory transduction protein kinase K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK D MGAS9429_Spy1628 salR; transcriptional regulatory protein K14989 salR; two-component system, NarL family, secretion system response regulator SalR D MGAS9429_Spy1601 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MGAS9429_Spy1340 atoD1; acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D MGAS9429_Spy0122 atoD2; acetate CoA-transferase alpha subunit K01034 atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9] D MGAS9429_Spy1341 atoA; acetate CoA-transferase beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] D MGAS9429_Spy0123 acetate CoA-transferase beta subunit K01035 atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9] D MGAS9429_Spy0119 atoE; short-chain fatty acids transporter K02106 atoE; short-chain fatty acids transporter D MGAS9429_Spy0431 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0121 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy1339 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy1300 two-component sensor kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D MGAS9429_Spy1274 two-component sensor kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D MGAS9429_Spy1299 two-component response regulator K07720 yesN; two-component system, response regulator YesN D MGAS9429_Spy0902 two-component response regulator K07720 yesN; two-component system, response regulator YesN D MGAS9429_Spy0037 protein tyrosine phosphatase K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:spk02024] D MGAS9429_Spy1345 luxS; autoinducer-2 production protein luxS K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21] D MGAS9429_Spy1703 trpG; anthranilate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D MGAS9429_Spy0432 long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MGAS9429_Spy1312 rocA; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D MGAS9429_Spy0205 fasB; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D MGAS9429_Spy0206 fasC; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D MGAS9429_Spy0207 fasA; response regulator K07707 agrA; two-component system, LytTR family, response regulator AgrA D MGAS9429_Spy0143 slo; streptolysin O K11031 slo; thiol-activated cytolysin D MGAS9429_Spy1050 ciaH; sensor protein K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D MGAS9429_Spy1051 ciaR; transcriptional regulatory protein K14983 ciaR; two-component system, OmpR family, response regulator CiaR D MGAS9429_Spy0251 oppA; oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein D MGAS9429_Spy0252 oppB; oligopeptide transport system permease protein K15581 oppB; oligopeptide transport system permease protein D MGAS9429_Spy0253 oppC; oligopeptide transport system permease protein K15582 oppC; oligopeptide transport system permease protein D MGAS9429_Spy0254 oppD; oligopeptide transport ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein D MGAS9429_Spy0255 oppF; oligopeptide transport ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein D MGAS9429_Spy0035 transcriptional regulator K20342 comR; HTH-type transcriptional regulator, regulator for ComX D MGAS9429_Spy0258 comX1-1; competence-specific sigma factor K12296 comX1_2; competence protein ComX D MGAS9429_Spy1621 comX2; competence-specific sigma factor K12296 comX1_2; competence protein ComX D MGAS9429_Spy0406 mutR; transcriptional regulator K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator D MGAS9429_Spy0439 transcriptional regulator K20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor D MGAS9429_Spy1710 dppA; dipeptide-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D MGAS9429_Spy1711 dppB; dipeptide transport system permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein D MGAS9429_Spy1712 dppC; dipeptide transport system permease protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein D MGAS9429_Spy1713 dppD; dipeptide transport ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D MGAS9429_Spy1714 dppE; dipeptide transport ATP-binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein D MGAS9429_Spy1746 rgg; transcriptional regulator K20375 ropB; HTH-type transcriptional regulator, pheromone-responsive regulator D MGAS9429_Spy1743 speB; streptopain precursor K01364 speB; streptopain [EC:3.4.22.10] D MGAS9429_Spy1397 lacD1; tagatose-bisphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D MGAS9429_Spy1638 lacD2; tagatose-bisphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D MGAS9429_Spy0209 60 kDa inner membrane protein YIDC K03217 yidC; YidC/Oxa1 family membrane protein insertase D MGAS9429_Spy0295 60 kDa inner membrane protein YIDC K03217 yidC; YidC/Oxa1 family membrane protein insertase D MGAS9429_Spy1761 secE; protein translocase subunit K03073 secE; preprotein translocase subunit SecE D MGAS9429_Spy0412 secG; protein translocase subunit K03075 secG; preprotein translocase subunit SecG D MGAS9429_Spy0064 secY; protein translocase subunit K03076 secY; preprotein translocase subunit SecY D MGAS9429_Spy1679 yajC; protein translocase subunit K03210 yajC; preprotein translocase subunit YajC D MGAS9429_Spy1538 secA; protein translocase subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D MGAS9429_Spy0464 ftsY; cell division protein K03110 ftsY; fused signal recognition particle receptor D MGAS9429_Spy1017 ffh; signal recognition particle subunit FFH/SRP54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D MGAS9429_Spy0926 serine/threonine dehydratase K20483 nisB; lantibiotic biosynthesis protein D MGAS9429_Spy0924 lanthionine synthetase K20484 nisC; lantibiotic biosynthesis protein D MGAS9429_Spy0923 srtT; lantibiotic transport permease protein K20485 nisT; ATP-binding cassette, subfamily B, bacterial NisT/SpaT D MGAS9429_Spy0921 srtK; lantibiotic biosynthesis sensor protein K20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3] D MGAS9429_Spy0920 srtR; lantibiotic biosynthesis two-component response regulator K20488 nisR; two-component system, OmpR family, lantibiotic biosynthesis response regulator NisR/SpaR D MGAS9429_Spy0927 srtF; lantibiotic transport ATP-binding protein K20490 nisF; lantibiotic transport system ATP-binding protein D MGAS9429_Spy0928 srtE; lantibiotic transport permease protein K20491 nisE; lantibiotic transport system permease protein D MGAS9429_Spy0929 srtG; lantibiotic transport permease protein K20492 nisG; lantibiotic transport system permease protein C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis C 02040 Flagellar assembly [PATH:spk02040] D MGAS9429_Spy0762 cystine-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D MGAS9429_Spy0269 ABC transporter substrate-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D MGAS9429_Spy0654 rpoD; RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D MGAS9429_Spy0609 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells D MGAS9429_Spy0108 fibronectin-binding protein K13734 sfb1; fibronectin-binding protein 1 D MGAS9429_Spy0111 fibronectin-binding protein K13734 sfb1; fibronectin-binding protein 1 D MGAS9429_Spy1736 fibronectin-binding protein K13734 sfb1; fibronectin-binding protein 1 D MGAS9429_Spy1738 fibronectin-binding protein K13734 sfb1; fibronectin-binding protein 1 B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance [PATH:spk01501] D MGAS9429_Spy0010 beta-lactamase K01467 ampC; beta-lactamase class C [EC:3.5.2.6] D MGAS9429_Spy0251 oppA; oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein D MGAS9429_Spy0252 oppB; oligopeptide transport system permease protein K15581 oppB; oligopeptide transport system permease protein D MGAS9429_Spy0253 oppC; oligopeptide transport system permease protein K15582 oppC; oligopeptide transport system permease protein D MGAS9429_Spy0254 oppD; oligopeptide transport ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein D MGAS9429_Spy0255 oppF; oligopeptide transport ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein D MGAS9429_Spy1351 pbp1A; multimodular transpeptidase-transglycosylase PBP 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D MGAS9429_Spy0082 pbp1b; multimodular transpeptidase-transglycosylase PBP 1B K03693 pbp1b; penicillin-binding protein 1B D MGAS9429_Spy1763 pbp2A; multimodular transpeptidase-transglycosylase PBP 2A K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D MGAS9429_Spy1363 division specific D,D-transpeptidase K12556 pbp2X; penicillin-binding protein 2X C 01502 Vancomycin resistance [PATH:spk01502] D MGAS9429_Spy1205 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D MGAS9429_Spy1536 acpS; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D MGAS9429_Spy1204 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D MGAS9429_Spy1362 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D MGAS9429_Spy1247 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D MGAS9429_Spy1504 D-alanyl-D-alanine metallocarboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:spk01503] D MGAS9429_Spy1877 htrA; endopeptidase K04771 degP; serine protease Do [EC:3.4.21.107] D MGAS9429_Spy0374 peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D MGAS9429_Spy1115 dltA; D-alanine-activating enzyme K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D MGAS9429_Spy1114 protein DltB K03739 dltB; membrane protein involved in D-alanine export D MGAS9429_Spy1113 D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D MGAS9429_Spy1112 dltD; protein dltD precursor K03740 dltD; D-alanine transfer protein D MGAS9429_Spy1723 sic1; complement inhibitor protein K19240 sic; inhibitor of complement-mediated lysis D MGAS9429_Spy1743 speB; streptopain precursor K01364 speB; streptopain [EC:3.4.22.10] B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:spk01000] C 01001 Protein kinases [BR:spk01001] D MGAS9429_Spy1330 serine/threonine protein kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] D MGAS9429_Spy0435 vicK; two-component sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] D MGAS9429_Spy1050 ciaH; sensor protein K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D MGAS9429_Spy0283 covS; transmembrane histidine kinase K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3] D MGAS9429_Spy1729 ihk; two-component system histidine kinase K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3] D MGAS9429_Spy0921 srtK; lantibiotic biosynthesis sensor protein K20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3] D MGAS9429_Spy1328 yvqE; two-component sensor protein K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3] D MGAS9429_Spy1629 sensory transduction protein kinase K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK D MGAS9429_Spy0950 dpiB; sensor kinase K02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3] D MGAS9429_Spy1312 rocA; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D MGAS9429_Spy0205 fasB; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D MGAS9429_Spy0206 fasC; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D MGAS9429_Spy1300 two-component sensor kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D MGAS9429_Spy1274 two-component sensor kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C 01009 Protein phosphatases and associated proteins [BR:spk01009] D MGAS9429_Spy1093 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D MGAS9429_Spy1331 pppL; protein phosphatase 2C K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16] C 01002 Peptidases and inhibitors [BR:spk01002] D MGAS9429_Spy0692 lsp; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] D MGAS9429_Spy1352 pepC; aminopeptidase C K01372 BLMH; bleomycin hydrolase [EC:3.4.22.40] D MGAS9429_Spy1743 speB; streptopain precursor K01364 speB; streptopain [EC:3.4.22.10] D MGAS9429_Spy0416 pcp; pyrrolidone-carboxylate peptidase K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3] D MGAS9429_Spy1021 guaA; GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D MGAS9429_Spy0960 glutamine amidotransferase, class I K07010 K07010; putative glutamine amidotransferase D MGAS9429_Spy0017 sibA; secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] D MGAS9429_Spy0024 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D MGAS9429_Spy1090 glmS; glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D MGAS9429_Spy0993 sortase K07284 srtA; sortase A [EC:3.4.22.70] D MGAS9429_Spy0110 sortase K07284 srtA; sortase A [EC:3.4.22.70] D MGAS9429_Spy0114 eftLSL-B; sortase B family protein K08600 srtB; sortase B [EC:3.4.22.71] D MGAS9429_Spy0595 pepD; dipeptidase A K08659 pepDA; dipeptidase [EC:3.4.-.-] D MGAS9429_Spy1176 CAAX amino terminal protease family K07052 K07052; CAAX protease family protein D MGAS9429_Spy0618 sagE; streptolysin S putative self-immunity protein K07052 K07052; CAAX protease family protein D MGAS9429_Spy1052 pepN; aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] D MGAS9429_Spy1183 pepB; oligoendopeptidase F K08602 pepF; oligoendopeptidase F [EC:3.4.24.-] D MGAS9429_Spy1793 pepO; oligoendopeptidase O K07386 pepO; putative endopeptidase [EC:3.4.24.-] D MGAS9429_Spy1504 D-alanyl-D-alanine metallocarboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D MGAS9429_Spy0907 Xaa-His dipeptidase K01274 pepV; beta-Ala-Xaa dipeptidase [EC:3.4.13.-] D MGAS9429_Spy0669 pepT; tripeptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] D MGAS9429_Spy1147 map; methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D MGAS9429_Spy0422 pepQ; Xaa-Pro aminopeptidase K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9] D MGAS9429_Spy1553 Xaa-Pro dipeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] D MGAS9429_Spy0013 ftsH; cell division protein K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D MGAS9429_Spy0098 pepA; glutamyl aminopeptidase K01261 pepA; glutamyl aminopeptidase [EC:3.4.11.7] D MGAS9429_Spy0279 endopeptidase K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D MGAS9429_Spy1675 membrane endopeptidase, M50 family K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] D MGAS9429_Spy1877 htrA; endopeptidase K04771 degP; serine protease Do [EC:3.4.21.107] D MGAS9429_Spy0344 spyCEP; interleukin-8 protease K01361 E3.4.21.96; lactocepin [EC:3.4.21.96] D MGAS9429_Spy1720 scpA; C5A peptidase precursor K08652 C5AP; C5a peptidase [EC:3.4.21.110] D MGAS9429_Spy0250 dacA2; D-alanyl-D-alanine serine-type carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D MGAS9429_Spy0936 dacA1; D-alanyl-D-alanine serine-type carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D MGAS9429_Spy0328 clpP; ATP-dependent endopeptidase clp proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D MGAS9429_Spy1582 pepXP; Xaa-Pro dipeptidyl-peptidase K01281 pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11] D MGAS9429_Spy1260 ATP-dependent endopeptidase K07177 K07177; Lon-like protease D MGAS9429_Spy1016 phage transcriptional repressor K01356 lexA; repressor LexA [EC:3.4.21.88] D MGAS9429_Spy1091 sipC; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D MGAS9429_Spy0112 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D MGAS9429_Spy1570 spi; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D MGAS9429_Spy0481 peptidase family U32 K08303 prtC; U32 family peptidase [EC:3.4.-.-] C 01003 Glycosyltransferases [BR:spk01003] D MGAS9429_Spy0425 1,2-diacylglycerol 3-glucosyltransferase K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D MGAS9429_Spy1862 hasA; hyaluronan synthase K00752 hasA; hyaluronan synthase [EC:2.4.1.212] D MGAS9429_Spy0424 glycosyltransferase K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208] D MGAS9429_Spy1351 pbp1A; multimodular transpeptidase-transglycosylase PBP 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D MGAS9429_Spy0082 pbp1b; multimodular transpeptidase-transglycosylase PBP 1B K03693 pbp1b; penicillin-binding protein 1B D MGAS9429_Spy1763 pbp2A; multimodular transpeptidase-transglycosylase PBP 2A K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D MGAS9429_Spy0242 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] C 01005 Lipopolysaccharide biosynthesis proteins [BR:spk01005] D MGAS9429_Spy0657 rgpAc; alpha-D-GlcNAc alpha-1,2-L-rhamnosyltransferase K12996 rgpA; rhamnosyltransferase [EC:2.4.1.-] D MGAS9429_Spy0658 rgpBc; alpha-L-Rha alpha-1,3-L-rhamnosyltransferase K12997 rgpB; rhamnosyltransferase [EC:2.4.1.-] D MGAS9429_Spy0662 rgpEc; glycosyltransferase K12998 rgpE; glucosyltransferase [EC:2.4.1.-] D MGAS9429_Spy0663 rgpFc; alpha-L-Rha alpha-1,2-L-rhamnosyltransferase K07272 rgpF; rhamnosyltransferase [EC:2.4.1.-] D MGAS9429_Spy0242 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D MGAS9429_Spy0419 bactoprenol glucosyl transferase K12999 rgpI; glucosyltransferase [EC:2.4.1.-] C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:spk01011] D MGAS9429_Spy1151 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D MGAS9429_Spy0638 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D MGAS9429_Spy0944 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D MGAS9429_Spy0290 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D MGAS9429_Spy1248 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D MGAS9429_Spy0324 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--lysine ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7] D MGAS9429_Spy1205 ddlA; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D MGAS9429_Spy1022 UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10] D MGAS9429_Spy0501 murM; UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10] D MGAS9429_Spy0500 factor essential for expression of methicillin resistance K12554 murN; alanine adding enzyme [EC:2.3.2.-] D MGAS9429_Spy1536 acpS; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D MGAS9429_Spy0302 glr; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D MGAS9429_Spy1362 phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D MGAS9429_Spy1247 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D MGAS9429_Spy0240 bacA; bacitracin resistance protein (putative undecaprenol kinase) K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D MGAS9429_Spy0313 membrane-associated phospholipid phosphatase K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D MGAS9429_Spy1351 pbp1A; multimodular transpeptidase-transglycosylase PBP 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D MGAS9429_Spy0082 pbp1b; multimodular transpeptidase-transglycosylase PBP 1B K03693 pbp1b; penicillin-binding protein 1B D MGAS9429_Spy1763 pbp2A; multimodular transpeptidase-transglycosylase PBP 2A K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D MGAS9429_Spy1363 division specific D,D-transpeptidase K12556 pbp2X; penicillin-binding protein 2X D MGAS9429_Spy0250 dacA2; D-alanyl-D-alanine serine-type carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D MGAS9429_Spy0936 dacA1; D-alanyl-D-alanine serine-type carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D MGAS9429_Spy1504 D-alanyl-D-alanine metallocarboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D MGAS9429_Spy0017 sibA; secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] D MGAS9429_Spy0993 sortase K07284 srtA; sortase A [EC:3.4.22.70] D MGAS9429_Spy0110 sortase K07284 srtA; sortase A [EC:3.4.22.70] D MGAS9429_Spy0114 eftLSL-B; sortase B family protein K08600 srtB; sortase B [EC:3.4.22.71] D MGAS9429_Spy0292 hypothetical membrane associated protein K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] C 01004 Lipid biosynthesis proteins [BR:spk01004] D MGAS9429_Spy1493 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D MGAS9429_Spy1496 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D MGAS9429_Spy1491 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D MGAS9429_Spy0362 short chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D MGAS9429_Spy1492 3-oxoacyl-(acyl-carrier protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D MGAS9429_Spy1489 fabZ; (3R)-hydroxyacyl-[acyl-carrier protein] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D MGAS9429_Spy1494 fabK; enoyl-(acyl-carrier protein) reductase (NADH) K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9] D MGAS9429_Spy1498 phaB; enoyl-CoA hydratase K18474 fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14] D MGAS9429_Spy0432 long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MGAS9429_Spy0020 plsX; fatty acid/phospholipid synthesis protein K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D MGAS9429_Spy0766 hypothetical membrane spanning protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D MGAS9429_Spy1197 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:spk01006] D MGAS9429_Spy1225 fps; dimethylallyltransferase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29] D MGAS9429_Spy1677 uppS; undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D MGAS9429_Spy0779 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] C 01007 Amino acid related enzymes [BR:spk01007] D MGAS9429_Spy0204 gltX; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D MGAS9429_Spy0081 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D MGAS9429_Spy1869 trsA; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D MGAS9429_Spy1656 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D MGAS9429_Spy1819 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D MGAS9429_Spy0348 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D MGAS9429_Spy1238 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D MGAS9429_Spy1286 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D MGAS9429_Spy0149 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D MGAS9429_Spy0485 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D MGAS9429_Spy1824 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D MGAS9429_Spy0528 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D MGAS9429_Spy1825 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D MGAS9429_Spy1383 glyQ; glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D MGAS9429_Spy1382 glyS; glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D MGAS9429_Spy1485 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D MGAS9429_Spy1674 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D MGAS9429_Spy0426 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D MGAS9429_Spy1179 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D MGAS9429_Spy0641 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D MGAS9429_Spy0642 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D MGAS9429_Spy1514 aspartate aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D MGAS9429_Spy0769 bcaT; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D MGAS9429_Spy1702 para-aminobenzoate synthetase component I K03342 pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins [BR:spk00194] D MGAS9429_Spy0636 atpC; ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D MGAS9429_Spy0635 atpD; ATP synthase beta chain K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D MGAS9429_Spy0634 atpG; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D MGAS9429_Spy0633 atpA; ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D MGAS9429_Spy0632 atpH; ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D MGAS9429_Spy0631 atpF; ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b D MGAS9429_Spy0629 atpE; ATP synthase C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c D MGAS9429_Spy0630 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:spk03000] D MGAS9429_Spy0915 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D MGAS9429_Spy1405 lacR1; lactose phosphotransferase system repressor K02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor D MGAS9429_Spy1642 lacR2; lactose phosphotransferase system repressor K02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor D MGAS9429_Spy0715 fruR; fructose repressor K03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor D MGAS9429_Spy1103 malR; transcriptional regulator, LacI family K02529 galR; LacI family transcriptional regulator, galactose operon repressor D MGAS9429_Spy1259 ribose operon repressor K02529 galR; LacI family transcriptional regulator, galactose operon repressor D MGAS9429_Spy0423 ccpA; catabolite control protein A K02529 galR; LacI family transcriptional regulator, galactose operon repressor D MGAS9429_Spy0508 regR; transcriptional regulator, LacI family K02525 kdgR; LacI family transcriptional regulator, kdg operon repressor D MGAS9429_Spy1548 scrR; sucrose operon repressor K03484 scrR; LacI family transcriptional regulator, sucrose operon repressor D MGAS9429_Spy1309 transcriptional regulator, GntR family K02103 araR; GntR family transcriptional regulator, arabinose operon transcriptional repressor D MGAS9429_Spy1796 trehalose operon transcriptional repressor K03486 treR2; GntR family transcriptional regulator, trehalose operon transcriptional repressor D MGAS9429_Spy1019 transcriptional regulator, GntR family K24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator D MGAS9429_Spy0597 transcriptional regulator, GntR family K24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator D MGAS9429_Spy1602 transcriptional regulator, MerR family K03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor D MGAS9429_Spy0163 perR; ferric uptake regulation protein K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator D MGAS9429_Spy1270 transcription regulator, crp family K21828 arcR; CRP/FNR family transcriptional regulator, arginine deiminase pathway regulator D MGAS9429_Spy1829 cadC; cadmium efflux system accessory protein K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor D MGAS9429_Spy1839 transcriptional regulator, PadR family K10947 K10947; PadR family transcriptional regulator D MGAS9429_Spy0370 scaR; iron-dependent repressor K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D MGAS9429_Spy1154 birA; biotin operon repressor K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D MGAS9429_Spy0035 transcriptional regulator K20342 comR; HTH-type transcriptional regulator, regulator for ComX D MGAS9429_Spy0406 mutR; transcriptional regulator K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator D MGAS9429_Spy0439 transcriptional regulator K20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor D MGAS9429_Spy1746 rgg; transcriptional regulator K20375 ropB; HTH-type transcriptional regulator, pheromone-responsive regulator D MGAS9429_Spy0230 purR; pur operon repressor K09685 purR; HTH-type transcriptional regulator, purine operon repressor D MGAS9429_Spy0961 AT-rich DNA-binding protein K01926 rex; redox-sensing transcriptional repressor D MGAS9429_Spy1513 codY; transcription pleiotropic repressor K03706 codY; transcriptional pleiotropic repressor D MGAS9429_Spy1178 transcriptional regulator, Cro/CI family K07729 K07729; putative transcriptional regulator D MGAS9429_Spy1649 transcriptional regulator, pbsX family K07729 K07729; putative transcriptional regulator D MGAS9429_Spy0466 licT; transcription antiterminator, BglG family K03488 licT; beta-glucoside operon transcriptional antiterminator D MGAS9429_Spy0157 transcription antiterminator, BglG family K03493 bglG1; transcriptional antiterminator D MGAS9429_Spy1126 transcription antiterminator, BglG family K03491 licR; probable licABCH operon transcriptional regulator D MGAS9429_Spy1878 parB; chromosome partitioning protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D MGAS9429_Spy1223 argR1; arginine repressor K03402 argR; transcriptional regulator of arginine metabolism D MGAS9429_Spy1271 ahrC2; arginine repressor K03402 argR; transcriptional regulator of arginine metabolism D MGAS9429_Spy1818 argR2; arginine repressor K03402 argR; transcriptional regulator of arginine metabolism D MGAS9429_Spy1502 hrcA; heat-inducible transcription repressor K03705 hrcA; heat-inducible transcriptional repressor D MGAS9429_Spy1774 ctsR; transcriptional regulator K03708 ctsR; transcriptional regulator of stress and heat shock response D MGAS9429_Spy0694 pyrR; uracil phosphoribosyltransferase K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] D MGAS9429_Spy0284 putative regulatory protein K07738 nrdR; transcriptional repressor NrdR D MGAS9429_Spy0258 comX1-1; competence-specific sigma factor K12296 comX1_2; competence protein ComX D MGAS9429_Spy1621 comX2; competence-specific sigma factor K12296 comX1_2; competence protein ComX C 03021 Transcription machinery [BR:spk03021] D MGAS9429_Spy0070 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D MGAS9429_Spy0083 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D MGAS9429_Spy0084 DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D MGAS9429_Spy0085 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D MGAS9429_Spy1614 rpoE; DNA-directed RNA polymerase delta chain K03048 rpoE; DNA-directed RNA polymerase subunit delta D MGAS9429_Spy1335 DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D MGAS9429_Spy0654 rpoD; RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor D MGAS9429_Spy1414 nusA; N utilization substance protein A K02600 nusA; transcription termination/antitermination protein NusA D MGAS9429_Spy1549 nusB; N utilization substance protein B K03625 nusB; transcription antitermination protein NusB D MGAS9429_Spy0140 nusG; transcription antitermination protein K02601 nusG; transcription termination/antitermination protein NusG D MGAS9429_Spy0293 greA; transcription elongation factor K03624 greA; transcription elongation factor GreA C 03019 Messenger RNA biogenesis [BR:spk03019] D MGAS9429_Spy0437 acpA; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D MGAS9429_Spy1600 Zn-dependent hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-] D MGAS9429_Spy0861 Zn-dependent hydrolase K12574 rnj; ribonuclease J [EC:3.1.-.-] D MGAS9429_Spy1337 hydrolase (HAD superfamily) K18682 rny; ribonucrease Y [EC:3.1.-.-] D MGAS9429_Spy0413 exoribonuclease II K12573 rnr; ribonuclease R [EC:3.1.13.1] D MGAS9429_Spy0229 cbf; CMP-binding factor K03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-] D MGAS9429_Spy1200 deaD; ATP-dependent RNA helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D MGAS9429_Spy1361 ATP-dependent RNA helicase K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7] D MGAS9429_Spy0609 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D MGAS9429_Spy1661 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D MGAS9429_Spy1093 pfk; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D MGAS9429_Spy1500 dnaK; chaperone protein K04043 dnaK; molecular chaperone DnaK D MGAS9429_Spy1771 groEL; 60 kDa chaperonin GROEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D MGAS9429_Spy0529 ATP-binding protein K06958 rapZ; RNase adapter protein RapZ C 03041 Spliceosome C 03011 Ribosome [BR:spk03011] D MGAS9429_Spy0771 SSU ribosomal protein S1P K02945 RP-S1; small subunit ribosomal protein S1 D MGAS9429_Spy1791 rpsB; SSU ribosomal protein S2P K02967 RP-S2; small subunit ribosomal protein S2 D MGAS9429_Spy0050 rpsC; SSU ribosomal protein S3P K02982 RP-S3; small subunit ribosomal protein S3 D MGAS9429_Spy1844 rpsD; SSU ribosomal protein S4P K02986 RP-S4; small subunit ribosomal protein S4 D MGAS9429_Spy0061 rpsE; SSU ribosomal protein S5P K02988 RP-S5; small subunit ribosomal protein S5 D MGAS9429_Spy1560 rpsF; SSU ribosomal protein S6P K02990 RP-S6; small subunit ribosomal protein S6 D MGAS9429_Spy0233 rpsG; SSU ribosomal protein S7P K02992 RP-S7; small subunit ribosomal protein S7 D MGAS9429_Spy0058 rpsH; SSU ribosomal protein S8P K02994 RP-S8; small subunit ribosomal protein S8 D MGAS9429_Spy1647 rpsI; SSU ribosomal protein S9P K02996 RP-S9; small subunit ribosomal protein S9 D MGAS9429_Spy0043 rpsJ; SSU ribosomal protein S10P K02946 RP-S10; small subunit ribosomal protein S10 D MGAS9429_Spy0069 rpsK; SSU ribosomal protein S11P K02948 RP-S11; small subunit ribosomal protein S11 D MGAS9429_Spy0232 rpsL; SSU ribosomal protein S12P K02950 RP-S12; small subunit ribosomal protein S12 D MGAS9429_Spy0068 rpsM; SSU ribosomal protein S13P K02952 RP-S13; small subunit ribosomal protein S13 D MGAS9429_Spy0057 rpsN; SSU ribosomal protein S14P K02954 RP-S14; small subunit ribosomal protein S14 D MGAS9429_Spy1595 rpsN2; SSU ribosomal protein S14P K02954 RP-S14; small subunit ribosomal protein S14 D MGAS9429_Spy1667 SSU ribosomal protein S15P K02956 RP-S15; small subunit ribosomal protein S15 D MGAS9429_Spy0704 rpsP; SSU ribosomal protein S16P K02959 RP-S16; small subunit ribosomal protein S16 D MGAS9429_Spy0053 rpsQ; SSU ribosomal protein S17P K02961 RP-S17; small subunit ribosomal protein S17 D MGAS9429_Spy1558 rpsR; SSU ribosomal protein S18P K02963 RP-S18; small subunit ribosomal protein S18 D MGAS9429_Spy0048 rpsS; SSU ribosomal protein S19P K02965 RP-S19; small subunit ribosomal protein S19 D MGAS9429_Spy1049 rpsT; SSU ribosomal protein S20P K02968 RP-S20; small subunit ribosomal protein S20 D MGAS9429_Spy0651 SSU ribosomal protein S21P K02970 RP-S21; small subunit ribosomal protein S21 D MGAS9429_Spy0378 rplA; LSU ribosomal protein L1P K02863 RP-L1; large subunit ribosomal protein L1 D MGAS9429_Spy0047 rplB; LSU ribosomal protein L2P K02886 RP-L2; large subunit ribosomal protein L2 D MGAS9429_Spy0044 rplC; LSU ribosomal protein L3P K02906 RP-L3; large subunit ribosomal protein L3 D MGAS9429_Spy0045 rplD; LSU ribosomal protein L1E (L4P) K02926 RP-L4; large subunit ribosomal protein L4 D MGAS9429_Spy0056 rplE; LSU ribosomal protein L5P K02931 RP-L5; large subunit ribosomal protein L5 D MGAS9429_Spy0059 rplF; LSU ribosomal protein L6P K02933 RP-L6; large subunit ribosomal protein L6 D MGAS9429_Spy1847 rplI; LSU ribosomal protein L9P K02939 RP-L9; large subunit ribosomal protein L9 D MGAS9429_Spy0909 rplJ; LSU ribosomal protein L10P K02864 RP-L10; large subunit ribosomal protein L10 D MGAS9429_Spy0377 rplK; LSU ribosomal protein L11P K02867 RP-L11; large subunit ribosomal protein L11 D MGAS9429_Spy0910 rplL; LSU ribosomal protein L12P (L7/L12) K02935 RP-L7; large subunit ribosomal protein L7/L12 D MGAS9429_Spy1648 rplM; LSU ribosomal protein L13P K02871 RP-L13; large subunit ribosomal protein L13 D MGAS9429_Spy0054 rplN; LSU ribosomal protein L14P K02874 RP-L14; large subunit ribosomal protein L14 D MGAS9429_Spy0063 rplO; LSU ribosomal protein L15P K02876 RP-L15; large subunit ribosomal protein L15 D MGAS9429_Spy0051 rplP; LSU ribosomal protein L16P K02878 RP-L16; large subunit ribosomal protein L16 D MGAS9429_Spy0071 rplQ; LSU ribosomal protein L17P K02879 RP-L17; large subunit ribosomal protein L17 D MGAS9429_Spy0060 rplR; LSU ribosomal protein L18P K02881 RP-L18; large subunit ribosomal protein L18 D MGAS9429_Spy0604 rplS; LSU ribosomal protein L19P K02884 RP-L19; large subunit ribosomal protein L19 D MGAS9429_Spy0676 rplT; LSU ribosomal protein L20P K02887 RP-L20; large subunit ribosomal protein L20 D MGAS9429_Spy0688 rplU; LSU ribosomal protein L21P K02888 RP-L21; large subunit ribosomal protein L21 D MGAS9429_Spy0049 rplV; LSU ribosomal protein L22P K02890 RP-L22; large subunit ribosomal protein L22 D MGAS9429_Spy0046 rplW; LSU ribosomal protein L23P K02892 RP-L23; large subunit ribosomal protein L23 D MGAS9429_Spy0055 rplX; LSU ribosomal protein L24P K02895 RP-L24; large subunit ribosomal protein L24 D MGAS9429_Spy0690 rpmA; LSU ribosomal protein L27P K02899 RP-L27; large subunit ribosomal protein L27 D MGAS9429_Spy1609 rpmB; LSU ribosomal protein L28P K02902 RP-L28; large subunit ribosomal protein L28 D MGAS9429_Spy0052 rpmC; LSU ribosomal protein L29P K02904 RP-L29; large subunit ribosomal protein L29 D MGAS9429_Spy0062 rpmD; LSU ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30 D MGAS9429_Spy0599 rpmE; LSU ribosomal protein L31P K02909 RP-L31; large subunit ribosomal protein L31 D MGAS9429_Spy1826 rpmF; LSU ribosomal protein L32P K02911 RP-L32; large subunit ribosomal protein L32 D MGAS9429_Spy0411 LSU ribosomal protein L33P K02913 RP-L33; large subunit ribosomal protein L33 D MGAS9429_Spy1762 LSU ribosomal protein L33P K02913 RP-L33; large subunit ribosomal protein L33 D MGAS9429_Spy1827 rpmG; LSU ribosomal protein L33P K02913 RP-L33; large subunit ribosomal protein L33 D MGAS9429_Spy0212 rpmH; LSU ribosomal protein L34P K02914 RP-L34; large subunit ribosomal protein L34 D MGAS9429_Spy0675 rpl36; LSU ribosomal protein L35P K02916 RP-L35; large subunit ribosomal protein L35 D MGAS9429_Spy0067 rpmJ; LSU ribosomal protein L36P K02919 RP-L36; large subunit ribosomal protein L36 D MGAS9429_SpyR0003 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0009 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0006 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0012 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0016 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0013 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0010 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0004 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0007 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0015 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0018 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0001 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0002 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0011 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0005 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0008 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0017 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0014 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:spk03009] D MGAS9429_Spy0437 acpA; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D MGAS9429_Spy0390 era; GTP-binding protein K03595 era; GTPase D MGAS9429_Spy1131 obg; GTP-binding protein CgtA K03979 obgE; GTPase [EC:3.6.5.-] D MGAS9429_Spy1414 nusA; N utilization substance protein A K02600 nusA; transcription termination/antitermination protein NusA D MGAS9429_Spy1549 nusB; N utilization substance protein B K03625 nusB; transcription antitermination protein NusB D MGAS9429_Spy0140 nusG; transcription antitermination protein K02601 nusG; transcription termination/antitermination protein NusG D MGAS9429_Spy1135 rsuA; ribosomal small subunit pseudouridine synthase A K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19] D MGAS9429_Spy1185 ribosomal small subunit pseudouridine synthase A K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19] D MGAS9429_Spy0223 ksgA; dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D MGAS9429_Spy1332 sunL; 16S rRNA m(5)C 967 methyltransferase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D MGAS9429_Spy1047 16S rRNA m(2)G 1207 methyltransferase K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172] D MGAS9429_Spy1262 methyltransferase K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171] D MGAS9429_Spy1694 hypothetical cytosolic protein K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193] D MGAS9429_Spy0277 gidB; methyltransferase K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D MGAS9429_Spy1365 mraW; S-adenosyl-methyltransferase K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199] D MGAS9429_Spy0338 tetrapyrrole (corrin/porphyrin) methylase family protein K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198] D MGAS9429_Spy1224 lantibotic precursor K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227] D MGAS9429_Spy1653 23S rRNA Gm2251 methyltransferase K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185] D MGAS9429_Spy1876 hypothetical cytosolic protein K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177] D MGAS9429_Spy0678 methyltransferase K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191] D MGAS9429_Spy1256 radical SAM family enzyme K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192] D MGAS9429_Spy1142 23S rRNA m(5)U 1939 methyltransferase K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190] D MGAS9429_Spy0309 ribosomal large subunit pseudouridine synthase B K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22] D MGAS9429_Spy0693 ribosomal large subunit pseudouridine synthase D K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D MGAS9429_Spy1766 ribosomal large subunit pseudouridine synthase D K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D MGAS9429_Spy0968 ribosomal large subunit pseudouridine synthase D K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D MGAS9429_Spy1597 ribosomal-protein-S18-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D MGAS9429_Spy0710 rimM; 16S rRNA processing protein K02860 rimM; 16S rRNA processing protein RimM D MGAS9429_Spy1695 ribosomal protein L11 methyltransferase K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-] D MGAS9429_Spy1807 endonuclease involved in recombination K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-] D MGAS9429_Spy1655 hypothetical protein K11145 mrnC; mini-ribonuclease III [EC:3.1.26.-] D MGAS9429_Spy1200 deaD; ATP-dependent RNA helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D MGAS9429_Spy1361 ATP-dependent RNA helicase K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7] D MGAS9429_Spy0225 GTPase K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D MGAS9429_Spy0287 pgdA; GTP-binding protein K03977 engA; GTPase D MGAS9429_Spy1000 GTP-binding protein K14540 rbgA; ribosome biogenesis GTPase A D MGAS9429_Spy0780 hflX; GTP-binding protein K03665 hflX; GTPase D MGAS9429_Spy0260 GTP-binding protein K06948 yqeH; 30S ribosome assembly GTPase D MGAS9429_Spy0982 sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D MGAS9429_Spy1689 relA; GTP pyrophosphokinase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D MGAS9429_Spy1410 rbfA; ribosome-binding factor A K02834 rbfA; ribosome-binding factor A D MGAS9429_Spy1415 hypothetical cytosolic protein K09748 rimP; ribosome maturation factor RimP D MGAS9429_Spy1865 hypothetical cytosolic protein K14761 rlbA; ribosome-associated protein D MGAS9429_Spy0264 iojap protein family K09710 ybeB; ribosome-associated protein D MGAS9429_Spy0388 hypothetical metal-binding protein K07042 ybeY; probable rRNA maturation factor D MGAS9429_Spy0261 hypothetical RNA binding protein K07574 yhbY; RNA-binding protein D MGAS9429_Spy1320 ribosome-associated factor Y K05808 hpf; ribosome hibernation promoting factor D MGAS9429_Spy0004 GTP-binding protein, probable translation factor K06942 ychF; ribosome-binding ATPase D MGAS9429_Spy0280 hypothetical cytosolic protein K07040 yceD; DUF177 domain-containing protein C 03016 Transfer RNA biogenesis [BR:spk03016] D MGAS9429_Spy0782 elaC; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11] D MGAS9429_Spy0728 papS; tRNA nucleotidyltransferase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] D MGAS9429_Spy1674 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D MGAS9429_Spy1238 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D MGAS9429_Spy0149 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D MGAS9429_Spy0348 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D MGAS9429_Spy1819 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D MGAS9429_Spy0485 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D MGAS9429_Spy1824 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D MGAS9429_Spy1179 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D MGAS9429_Spy0528 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D MGAS9429_Spy0426 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D MGAS9429_Spy1485 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D MGAS9429_Spy1656 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D MGAS9429_Spy1286 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D MGAS9429_Spy1825 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D MGAS9429_Spy0641 pheS; phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D MGAS9429_Spy0642 pheT; phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D MGAS9429_Spy0081 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D MGAS9429_Spy1869 trsA; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D MGAS9429_Spy1688 D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96] D MGAS9429_Spy1474 hit; adenosine 5'-monophosphoramidase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D MGAS9429_Spy1470 tRNA (m(7)G46) methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] D MGAS9429_Spy1620 tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D MGAS9429_Spy1065 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D MGAS9429_Spy0685 nifS1; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D MGAS9429_Spy0963 nifS2; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D MGAS9429_Spy0982 sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D MGAS9429_Spy0779 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D MGAS9429_Spy0908 thdF; tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-] D MGAS9429_Spy1849 gidA; putative tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase subunit K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D MGAS9429_Spy0208 fasX; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5] D MGAS9429_Spy1383 glyQ; glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D MGAS9429_Spy1382 glyS; glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D MGAS9429_Spy0204 gltX; glutamyl-tRNA synthetase K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D MGAS9429_Spy0488 transcriptional regulator K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-] D MGAS9429_Spy0182 tRNA-specific adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33] D MGAS9429_Spy0105 tRNA-dihydrouridine synthase K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-] D MGAS9429_Spy1010 gid; glucose inhibited division protein A K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D MGAS9429_Spy0711 trmD; tRNA (Guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D MGAS9429_Spy0789 hypothetical cytosolic protein K06967 trmK; tRNA (adenine22-N1)-methyltransferase [EC:2.1.1.217] D MGAS9429_Spy0311 23S rRNA methyltransferase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207] D MGAS9429_Spy0297 23S rRNA methyltransferase K03437 spoU; RNA methyltransferase, TrmH family D MGAS9429_Spy1851 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D MGAS9429_Spy1187 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17] D MGAS9429_Spy0520 iron-sulfur cluster-binding protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6] D MGAS9429_Spy0199 hypothetical cytosolic protein K09765 queH; epoxyqueuosine reductase [EC:1.17.99.6] D MGAS9429_Spy0177 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29] D MGAS9429_Spy0686 thiI; thiamine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D MGAS9429_Spy0011 tilS; tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19] D MGAS9429_Spy1598 non-proteolytic protein, peptidase family M22 K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB D MGAS9429_Spy1596 O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234] D MGAS9429_Spy1478 ATP/GTP hydrolase K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE D MGAS9429_Spy0266 hypothetical cytosolic protein K27343 tmcAL; tRNA(Met) cytidine acetate ligase [EC:6.3.4.-] D MGAS9429_Spy0413 exoribonuclease II K12573 rnr; ribonuclease R [EC:3.1.13.1] D MGAS9429_Spy1661 polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] C 03012 Translation factors [BR:spk03012] D MGAS9429_Spy1411 infB; bacterial protein translation initiation factor 2 (IF-2) K02519 infB; translation initiation factor IF-2 D MGAS9429_Spy0674 infC; bacterial protein translation initiation factor 3 (IF-3) K02520 infC; translation initiation factor IF-3 D MGAS9429_Spy0864 ABC transporter ATP-binding protein K06158 ABCF3; ATP-binding cassette, subfamily F, member 3 D MGAS9429_Spy1792 translation elongation factor Ts (EF-Ts) K02357 tsf; elongation factor Ts D MGAS9429_Spy0498 translation elongation factor Tu (EF-TU) K02358 tuf; elongation factor Tu D MGAS9429_Spy0234 fus; translation elongation factor G (EF-G) K02355 fusA; elongation factor G D MGAS9429_Spy0980 prfA; bacterial peptide chain release factor 1 (RF-1) K02835 prfA; peptide chain release factor 1 D MGAS9429_Spy0380 rrf; ribosome recycling factor (RRF) K02838 frr; ribosome recycling factor D MGAS9429_Spy0981 hemK; peptide release factor-glutamine N5-methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D MGAS9429_Spy0005 pth; peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D MGAS9429_Spy0066 infA; bacterial protein translation initiation factor 1 (IF-1) K02518 infA; translation initiation factor IF-1 D MGAS9429_Spy1551 efp; translation elongation factor P (EF-P) K02356 efp; elongation factor P D MGAS9429_Spy0521 prfB; bacterial peptide chain release factor 2 (RF-2) K02836 prfB; peptide chain release factor 2 D MGAS9429_Spy1202 prfC; bacterial peptide chain release factor 3 (RF-3) K02837 prfC; peptide chain release factor 3 C 03110 Chaperones and folding catalysts [BR:spk03110] D MGAS9429_Spy1773 clpC; negative regulator of genetic competence K03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC D MGAS9429_Spy1235 clpE; ATP-dependent endopeptidase clp ATP-binding subunit K03697 clpE; ATP-dependent Clp protease ATP-binding subunit ClpE D MGAS9429_Spy0750 clpL; ATP-dependent endopeptidase clp ATP-binding subunit K04086 clpL; ATP-dependent Clp protease ATP-binding subunit ClpL D MGAS9429_Spy0747 clpX; ATP-dependent endopeptidase clp ATP-binding subunit K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX D MGAS9429_Spy1500 dnaK; chaperone protein K04043 dnaK; molecular chaperone DnaK D MGAS9429_Spy1771 groEL; 60 kDa chaperonin GROEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D MGAS9429_Spy1499 dnaJ; chaperone protein K03686 dnaJ; molecular chaperone DnaJ D MGAS9429_Spy0106 33 kDa chaperonin K04083 hslO; molecular chaperone Hsp33 D MGAS9429_Spy1501 grpE; GrpE protein K03687 GRPE; molecular chaperone GrpE D MGAS9429_Spy1772 groES; 10 kDa chaperonin GROES K04078 groES; chaperonin GroES D MGAS9429_Spy1877 htrA; endopeptidase K04771 degP; serine protease Do [EC:3.4.21.107] D MGAS9429_Spy0013 ftsH; cell division protein K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D MGAS9429_Spy0630 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a D MGAS9429_Spy0344 spyCEP; interleukin-8 protease K01361 E3.4.21.96; lactocepin [EC:3.4.21.96] D MGAS9429_Spy1720 scpA; C5A peptidase precursor K08652 C5AP; C5a peptidase [EC:3.4.21.110] D MGAS9429_Spy0374 peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D MGAS9429_Spy1326 peptidyl-prolyl cis-trans isomerase K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] D MGAS9429_Spy1740 peptidyl-prolyl cis-trans isomerase K07533 prsA; foldase protein PrsA [EC:5.2.1.8] D MGAS9429_Spy1180 surA; peptidyl-prolyl cis-trans isomerase K07533 prsA; foldase protein PrsA [EC:5.2.1.8] D MGAS9429_Spy1564 trx; thioredoxin K03671 TXN; thioredoxin C 04131 Membrane trafficking [BR:spk04131] D MGAS9429_Spy0890 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D MGAS9429_Spy1311 alpha-mannosidase K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24] D MGAS9429_Spy0235 plr; glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D MGAS9429_Spy1212 gpmA; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D MGAS9429_Spy1092 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] C 04121 Ubiquitin system C 03051 Proteasome C 03032 DNA replication proteins [BR:spk03032] D MGAS9429_Spy0915 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D MGAS9429_Spy1217 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta D MGAS9429_Spy0001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein D MGAS9429_Spy1846 holB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D MGAS9429_Spy0653 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D MGAS9429_Spy0285 dnaB; replicative DNA helicase K03346 dnaB; replication initiation and membrane attachment protein D MGAS9429_Spy0286 dnaI; primosomal protein K11144 dnaI; primosomal protein DnaI D MGAS9429_Spy0103 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D MGAS9429_Spy1559 ssb3; single strand binding protein K03111 ssb; single-strand DNA-binding protein D MGAS9429_Spy1094 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D MGAS9429_Spy1673 polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D MGAS9429_Spy0002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D MGAS9429_Spy1193 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D MGAS9429_Spy0333 dnaX; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D MGAS9429_Spy1587 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D MGAS9429_Spy1159 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D MGAS9429_Spy1001 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D MGAS9429_Spy1569 ribonuclease HIII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4] D MGAS9429_Spy0161 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D MGAS9429_Spy0627 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D MGAS9429_Spy0992 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D MGAS9429_Spy0606 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D MGAS9429_Spy0768 parC; topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D MGAS9429_Spy0767 parE; topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D MGAS9429_Spy1003 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] C 03036 Chromosome and associated proteins [BR:spk03036] D MGAS9429_Spy0915 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D MGAS9429_Spy0437 acpA; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D MGAS9429_Spy1217 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta D MGAS9429_Spy0001 dnaA; chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein D MGAS9429_Spy1254 dpr; non-specific DNA-binding protein Dps K04047 dps; starvation-inducible DNA-binding protein D MGAS9429_Spy0438 smc; chromosome partition protein K03529 smc; chromosome segregation protein D MGAS9429_Spy0307 segregation and condensation protein K05896 scpA; segregation and condensation protein A D MGAS9429_Spy0308 segregation and condensation protein K06024 scpB; segregation and condensation protein B D MGAS9429_Spy1245 ftsA; cell division protein K03590 ftsA; cell division protein FtsA D MGAS9429_Spy0008 divIC; cell division protein K13052 divIC; cell division protein DivIC D MGAS9429_Spy0522 ftsE; cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein D MGAS9429_Spy0375 ftsK; cell division protein K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family D MGAS9429_Spy1364 ftsL; cell division protein K03586 ftsL; cell division protein FtsL D MGAS9429_Spy1246 divIB; cell division protein K03589 ftsQ; cell division protein FtsQ D MGAS9429_Spy0496 ftsW; cell division protein K03588 ftsW; cell division protein FtsW D MGAS9429_Spy0523 ftsX; cell division protein K09811 ftsX; cell division transport system permease protein D MGAS9429_Spy1244 ftsZ; cell division protein K03531 ftsZ; cell division protein FtsZ D MGAS9429_Spy0607 septation ring formation regulator K06286 ezrA; septation ring formation regulator D MGAS9429_Spy1239 divIVAS; cell division initiation protein K04074 divIVA; cell division initiation protein D MGAS9429_Spy1242 hypothetical cytosolic protein K09772 sepF; cell division inhibitor SepF D MGAS9429_Spy1878 parB; chromosome partitioning protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D MGAS9429_Spy0768 parC; topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D MGAS9429_Spy0767 parE; topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D MGAS9429_Spy1849 gidA; putative tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase subunit K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D MGAS9429_Spy0277 gidB; methyltransferase K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D MGAS9429_Spy1010 gid; glucose inhibited division protein A K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D MGAS9429_Spy0748 GTP-binding protein YihA K03978 engB; GTP-binding protein D MGAS9429_Spy0531 hypothetical cytosolic protein K09762 whiA; cell division protein WhiA C 03400 DNA repair and recombination proteins [BR:spk03400] D MGAS9429_Spy1231 phr; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D MGAS9429_Spy0764 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D MGAS9429_Spy1562 mutY; A/G-specific adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D MGAS9429_Spy0788 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D MGAS9429_Spy0852 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D MGAS9429_Spy1236 mutT; mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D MGAS9429_Spy0200 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D MGAS9429_Spy1812 tag; DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D MGAS9429_Spy0407 fpg; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D MGAS9429_Spy0342 exoA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D MGAS9429_Spy0784 single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D MGAS9429_Spy0785 recJ; single-stranded-DNA-specific exonuclease recJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D MGAS9429_Spy0627 lig; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D MGAS9429_Spy0161 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D MGAS9429_Spy1554 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A D MGAS9429_Spy1117 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B D MGAS9429_Spy0905 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C D MGAS9429_Spy1080 pcrA; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D MGAS9429_Spy0083 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D MGAS9429_Spy0084 DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D MGAS9429_Spy0085 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D MGAS9429_Spy0070 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D MGAS9429_Spy1614 rpoE; DNA-directed RNA polymerase delta chain K03048 rpoE; DNA-directed RNA polymerase subunit delta D MGAS9429_Spy1335 DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D MGAS9429_Spy0006 trcF; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D MGAS9429_Spy1816 mutS; DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS D MGAS9429_Spy1566 mutS2; DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2 D MGAS9429_Spy1815 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL D MGAS9429_Spy1227 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D MGAS9429_Spy1226 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D MGAS9429_Spy1094 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D MGAS9429_Spy1673 polC; DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D MGAS9429_Spy0002 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D MGAS9429_Spy1193 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D MGAS9429_Spy0333 dnaX; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D MGAS9429_Spy1587 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D MGAS9429_Spy1159 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D MGAS9429_Spy0103 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D MGAS9429_Spy1559 ssb3; single strand binding protein K03111 ssb; single-strand DNA-binding protein D MGAS9429_Spy1571 recD; exodeoxyribonuclease V alpha chain K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D MGAS9429_Spy1810 recA; RecA protein K03553 recA; recombination protein RecA D MGAS9429_Spy1813 ruvA; holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA D MGAS9429_Spy0036 ruvB; holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D MGAS9429_Spy1334 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D MGAS9429_Spy0201 radA; DNA repair protein K04485 radA; DNA repair protein RadA/Sms D MGAS9429_Spy1866 recF; DNA replication and repair protein K03629 recF; DNA replication and repair protein RecF D MGAS9429_Spy1521 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D MGAS9429_Spy0019 recO; DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O) D MGAS9429_Spy1206 recR; recombination protein K06187 recR; recombination protein RecR D MGAS9429_Spy1222 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N) D MGAS9429_Spy1350 recU; recombination protein K03700 recU; recombination protein U D MGAS9429_Spy0649 rexA; ATP-dependent nuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-] D MGAS9429_Spy0648 rexB; ATP-dependent nuclease subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-] D MGAS9429_Spy1280 hypothetical protein K15342 cas1; CRISP-associated protein Cas1 D MGAS9429_Spy0886 hypothetical cytosolic protein K15342 cas1; CRISP-associated protein Cas1 D MGAS9429_Spy0409 ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase D MGAS9429_Spy0992 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D MGAS9429_Spy0606 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D MGAS9429_Spy1003 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D MGAS9429_Spy1217 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta D MGAS9429_Spy1573 dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D MGAS9429_Spy1016 phage transcriptional repressor K01356 lexA; repressor LexA [EC:3.4.21.88] D MGAS9429_Spy1314 recX; regulatory protein K03565 recX; regulatory protein D MGAS9429_Spy0526 dinG; ATP-dependent helicase, DinG family K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D MGAS9429_Spy1170 nrdE2; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D MGAS9429_Spy0352 nrdE1; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D MGAS9429_Spy1171 nrdF2; ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D MGAS9429_Spy0350 nrdF1; ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D MGAS9429_Spy0600 phosphoesterase, DHH family protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] C 03029 Mitochondrial biogenesis [BR:spk03029] D MGAS9429_Spy1411 infB; bacterial protein translation initiation factor 2 (IF-2) K02519 infB; translation initiation factor IF-2 D MGAS9429_Spy0674 infC; bacterial protein translation initiation factor 3 (IF-3) K02520 infC; translation initiation factor IF-3 D MGAS9429_Spy1792 translation elongation factor Ts (EF-Ts) K02357 tsf; elongation factor Ts D MGAS9429_Spy0498 translation elongation factor Tu (EF-TU) K02358 tuf; elongation factor Tu D MGAS9429_Spy0234 fus; translation elongation factor G (EF-G) K02355 fusA; elongation factor G D MGAS9429_Spy0390 era; GTP-binding protein K03595 era; GTPase D MGAS9429_Spy0081 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D MGAS9429_Spy0149 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D MGAS9429_Spy1824 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D MGAS9429_Spy1819 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D MGAS9429_Spy1509 gatA; aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D MGAS9429_Spy1508 gatB; aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D MGAS9429_Spy1510 gatC; glutamyl-tRNA(Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D MGAS9429_Spy0103 single-strand DNA binding protein K03111 ssb; single-strand DNA-binding protein D MGAS9429_Spy1559 ssb3; single strand binding protein K03111 ssb; single-strand DNA-binding protein D MGAS9429_Spy1500 dnaK; chaperone protein K04043 dnaK; molecular chaperone DnaK D MGAS9429_Spy1501 grpE; GrpE protein K03687 GRPE; molecular chaperone GrpE D MGAS9429_Spy1771 groEL; 60 kDa chaperonin GROEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D MGAS9429_Spy1772 groES; 10 kDa chaperonin GROES K04078 groES; chaperonin GroES D MGAS9429_Spy1499 dnaJ; chaperone protein K03686 dnaJ; molecular chaperone DnaJ D MGAS9429_Spy0685 nifS1; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D MGAS9429_Spy0963 nifS2; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D MGAS9429_Spy0209 60 kDa inner membrane protein YIDC K03217 yidC; YidC/Oxa1 family membrane protein insertase D MGAS9429_Spy0295 60 kDa inner membrane protein YIDC K03217 yidC; YidC/Oxa1 family membrane protein insertase B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:spk02000] D MGAS9429_Spy0923 srtT; lantibiotic transport permease protein K20485 nisT; ATP-binding cassette, subfamily B, bacterial NisT/SpaT D MGAS9429_Spy0197 multidrug resistance ABC transporter ATP-binding and permease protein K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump D MGAS9429_Spy0198 multidrug/protein/lipid ABC transporter family, ATP-binding and permease protein K18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump D MGAS9429_Spy0988 multidrug resistance ABC transporter ATP-binding and permease protein K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump D MGAS9429_Spy0989 multidrug resistance ABC transporter ATP-binding and permease protein K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump D MGAS9429_Spy1632 salX; lacticin 481/lactococcin biosynthesis protein LCNDR2 K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial D MGAS9429_Spy1527 ABC transporter ATP-binding protein K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial D MGAS9429_Spy1528 ABC transporter ATP-binding protein K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial D MGAS9429_Spy0729 ABC transporter ATP-binding protein K15738 uup; ABC transport system ATP-binding/permease protein D MGAS9429_Spy0903 iron(III)-binding protein K02012 afuA; iron(III) transport system substrate-binding protein D MGAS9429_Spy0948 spermidine/putrescine-binding protein K11069 potD; spermidine/putrescine transport system substrate-binding protein D MGAS9429_Spy0947 potC; spermidine/putrescine transport system permease protein K11070 potC; spermidine/putrescine transport system permease protein D MGAS9429_Spy0946 potB; spermidine/putrescine transport system permease protein K11071 potB; spermidine/putrescine transport system permease protein D MGAS9429_Spy0945 potA; spermidine/putrescine transport ATP-binding protein K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] D MGAS9429_Spy0160 opuABC; glycine betaine-binding protein K02001 proW; glycine betaine/proline transport system permease protein D MGAS9429_Spy0159 opuAA; glycine betaine transport ATP-binding protein K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9] D MGAS9429_Spy0973 glycine betaine transport system permease protein K05845 opuC; osmoprotectant transport system substrate-binding protein D MGAS9429_Spy0972 proV; glycine betaine transport ATP-binding protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] D MGAS9429_Spy1685 msmK; multiple sugar transport ATP-binding protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D MGAS9429_Spy1104 malX; maltose/maltodextrin-binding protein K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein D MGAS9429_Spy1105 malC; maltodextrin transport system permease protein K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D MGAS9429_Spy1106 malD; maltose transport system permease protein K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D MGAS9429_Spy1302 sugar-binding protein K17318 lplA; putative aldouronate transport system substrate-binding protein D MGAS9429_Spy1304 sugar transport system permease protein K17319 lplB; putative aldouronate transport system permease protein D MGAS9429_Spy1303 sugar transport system permease protein K17320 lplC; putative aldouronate transport system permease protein D MGAS9429_Spy0139 nucleoside-binding protein K07335 bmpA; basic membrane protein A and related proteins D MGAS9429_Spy1045 nucleoside-binding protein K07335 bmpA; basic membrane protein A and related proteins D MGAS9429_Spy1043 nucleoside transport system permease protein K23535 nupB; general nucleoside transport system permease protein D MGAS9429_Spy1042 nucleoside transport system permease protein K23536 nupC; general nucleoside transport system permease protein D MGAS9429_Spy1044 nucleoside transport ATP-binding protein K23537 nupA; general nucleoside transport system ATP-binding protein D MGAS9429_Spy0214 N-acetylneuraminate-binding protein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D MGAS9429_Spy0215 N-acetylneuraminate transport system permease protein K02025 ABC.MS.P; multiple sugar transport system permease protein D MGAS9429_Spy0216 N-acetylneuraminate transport system permease protein K02026 ABC.MS.P1; multiple sugar transport system permease protein D MGAS9429_Spy1059 pstS; phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein D MGAS9429_Spy1058 pstC; phosphate transport system permease protein K02037 pstC; phosphate transport system permease protein D MGAS9429_Spy1057 pstA; phosphate transport system permease protein K02038 pstA; phosphate transport system permease protein D MGAS9429_Spy1055 pstB; phosphate transport ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D MGAS9429_Spy1056 pstB2; phosphate transport ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D MGAS9429_Spy1118 glnH; glutamine-binding protein K10036 glnH; glutamine transport system substrate-binding protein D MGAS9429_Spy1119 glnQ2; glutamine transport ATP-binding protein K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1] D MGAS9429_Spy0762 cystine-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D MGAS9429_Spy0269 ABC transporter substrate-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D MGAS9429_Spy0763 cystine transport system permease protein K10009 tcyB; L-cystine transport system permease protein D MGAS9429_Spy1359 amino acid ABC transporter permease protein K10009 tcyB; L-cystine transport system permease protein D MGAS9429_Spy1358 amino acid transport ATP-binding protein K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1] D MGAS9429_Spy0650 arginine-binding protein K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein D MGAS9429_Spy1233 artQ; arginine transport system permease protein K17077 artQ; arginine/lysine/histidine transport system permease protein D MGAS9429_Spy1232 artP; arginine transport ATP-binding protein K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1] D MGAS9429_Spy0270 ABC transporter substrate-binding protein K02073 metQ; D-methionine transport system substrate-binding protein D MGAS9429_Spy0272 ABC transporter permease protein K02072 metI; D-methionine transport system permease protein D MGAS9429_Spy0271 ABC transporter ATP-binding protein K02071 metN; D-methionine transport system ATP-binding protein D MGAS9429_Spy0857 ABC transporter substrate-binding protein K01989 K01989; putative tryptophan/tyrosine transport system substrate-binding protein D MGAS9429_Spy0859 ABC transporter permease protein K05832 K05832; putative tryptophan/tyrosine transport system permease protein D MGAS9429_Spy0860 ABC transporter ATP-binding protein K05833 K05833; putative tryptophan/tyrosine transport system ATP-binding protein D MGAS9429_Spy0238 ABC transporter amino acid-binding protein K17073 lysX1; putative lysine transport system substrate-binding protein D MGAS9429_Spy0237 amino acid transport ATP-binding protein K17076 lysY; putative lysine transport system ATP-binding protein D MGAS9429_Spy1086 histidine-binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein D MGAS9429_Spy1088 histidine transport system permease protein K02029 ABC.PA.P; polar amino acid transport system permease protein D MGAS9429_Spy1087 histidine transport ATP-binding protein K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1] D MGAS9429_Spy0251 oppA; oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein D MGAS9429_Spy0252 oppB; oligopeptide transport system permease protein K15581 oppB; oligopeptide transport system permease protein D MGAS9429_Spy0253 oppC; oligopeptide transport system permease protein K15582 oppC; oligopeptide transport system permease protein D MGAS9429_Spy0254 oppD; oligopeptide transport ATP-binding protein K15583 oppD; oligopeptide transport system ATP-binding protein D MGAS9429_Spy0255 oppF; oligopeptide transport ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein D MGAS9429_Spy1710 dppA; dipeptide-binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D MGAS9429_Spy1711 dppB; dipeptide transport system permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein D MGAS9429_Spy1712 dppC; dipeptide transport system permease protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein D MGAS9429_Spy1713 dppD; dipeptide transport ATP-binding protein K02031 ddpD; peptide/nickel transport system ATP-binding protein D MGAS9429_Spy1714 dppE; dipeptide transport ATP-binding protein K02032 ddpF; peptide/nickel transport system ATP-binding protein D MGAS9429_Spy0322 fhuD; ferrichrome-binding protein K25308 fhuD; ferric hydroxamate/heme transport system substrate-binding protein D MGAS9429_Spy0321 fhuB; ferrichrome transport system permease protein K25288 fhuB; ferric hydroxamate/heme transport system permease protein D MGAS9429_Spy0320 fhuG; ferrichrome transport system permease protein K25289 fhuG; ferric hydroxamate/heme transport system permease protein D MGAS9429_Spy0323 fhuA; ferrichrome transport ATP-binding protein K25290 fhuA; ferric hydroxamate/heme transport system ATP-binding protein [EC:7.2.2.16] D MGAS9429_Spy1532 ferrichrome-binding protein K25113 htsA; heme transport system substrate-binding protein D MGAS9429_Spy1531 ferrichrome transport system permease protein K25114 htsB; heme transport system permease protein D MGAS9429_Spy1529 fhuC; ferrichrome transport ATP-binding protein K25115 htsC; heme transport system ATP-binding protein [EC:7.6.2.5] D MGAS9429_Spy1533 shp; hypothetical protein K25119 shp; heme transport system cell surface heme-binding protein D MGAS9429_Spy1534 putative Fe3+-siderophore transport protein K25120 shr; heme sequestration protein D MGAS9429_Spy0596 high-affinity zinc uptake system protein znuA precursor K09815 znuA; zinc transport system substrate-binding protein D MGAS9429_Spy1717 lmb; laminin-binding surface protein K09815 znuA; zinc transport system substrate-binding protein D MGAS9429_Spy0079 adcB; high-affinity zinc uptake system membrane protein K09816 znuB; zinc transport system permease protein D MGAS9429_Spy0078 adcC; high-affinity zinc uptake system ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D MGAS9429_Spy0371 mtsA; manganese-binding protein K11704 mtsA; iron/zinc/manganese/copper transport system substrate-binding protein D MGAS9429_Spy0373 mtsC; manganese transport system membrane protein K11705 mtsC; iron/zinc/manganese/copper transport system permease protein D MGAS9429_Spy0372 mtsB; manganese transport system ATP-binding protein K11706 mtsB; iron/zinc/manganese/copper transport system ATP-binding protein D MGAS9429_Spy0179 BioY protein K03523 bioY; biotin transport system substrate-specific component D MGAS9429_Spy1526 membrane-bound protein K16926 htsT; energy-coupling factor transport system substrate-specific component D MGAS9429_Spy0491 integral membrane protein K16927 cbrT; energy-coupling factor transport system substrate-specific component D MGAS9429_Spy1855 cbiQ; hyaluronan ABC exporter permease protein K16785 ecfT; energy-coupling factor transport system permease protein D MGAS9429_Spy1525 cobalt transport protein K16785 ecfT; energy-coupling factor transport system permease protein D MGAS9429_Spy1857 cbiO1; hyaluronan ABC exporter ATP-binding protein K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D MGAS9429_Spy1856 cbiO2; hyaluronan ABC exporter ATP-binding protein K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D MGAS9429_Spy1524 cobalt transport ATP-binding protein K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D MGAS9429_Spy0928 srtE; lantibiotic transport permease protein K20491 nisE; lantibiotic transport system permease protein D MGAS9429_Spy0929 srtG; lantibiotic transport permease protein K20492 nisG; lantibiotic transport system permease protein D MGAS9429_Spy0927 srtF; lantibiotic transport ATP-binding protein K20490 nisF; lantibiotic transport system ATP-binding protein D MGAS9429_Spy0623 sagI; streptolysin S export transmembrane protein K25142 lnrN; linearmycin/streptolysin S transport system permease protein D MGAS9429_Spy0622 sagH; streptolysin S export transmembrane protein K25143 lnrM; linearmycin/streptolysin S transport system permease protein D MGAS9429_Spy0620 sagG; streptolysin S export ATP-binding protein K25144 lnrL; linearmycin/streptolysin S transport system ATP-binding protein D MGAS9429_Spy0702 ABC transporter permease protein K24948 yknZ; antimicrobial peptide resistance transport system permease protein D MGAS9429_Spy1731 ABC transporter permease protein K24948 yknZ; antimicrobial peptide resistance transport system permease protein D MGAS9429_Spy0701 ABC transporter ATP-binding protein K24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-] D MGAS9429_Spy1732 ABC transporter ATP-binding protein K24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-] D MGAS9429_Spy0523 ftsX; cell division protein K09811 ftsX; cell division transport system permease protein D MGAS9429_Spy0522 ftsE; cell division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein D MGAS9429_Spy0429 ABC transporter permease protein K25154 evrC; viologen exporter family transport system permease protein D MGAS9429_Spy0428 daunorubicin resistance transmembrane protein K25155 evrB; viologen exporter family transport system permease protein D MGAS9429_Spy0427 drrA; daunorubicin resistance ATP-binding protein K25156 evrA; viologen exporter family transport system ATP-binding protein D MGAS9429_Spy1472 protein ecsB K25157 ecsB; ABC-2 type transport system permease protein D MGAS9429_Spy1473 ABC-type transporter ATP-binding protein K25158 ecsA; ABC-2 type transport system ATP-binding protein D MGAS9429_Spy0660 rgpCc; polysaccharide export ABC transporter permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein D MGAS9429_Spy1370 proB; ABC transporter permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein D MGAS9429_Spy0621 streptolysin S export transmembrane protein K01992 ABC-2.P; ABC-2 type transport system permease protein D MGAS9429_Spy1519 ABC transporter permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein D MGAS9429_Spy1096 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D MGAS9429_Spy1371 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D MGAS9429_Spy0661 rgpDc; polysaccharide export ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D MGAS9429_Spy1520 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D MGAS9429_Spy1069 ABC transporter permease protein K02004 ABC.CD.P; putative ABC transport system permease protein D MGAS9429_Spy0645 ABC transporter permease protein K02004 ABC.CD.P; putative ABC transport system permease protein D MGAS9429_Spy1630 salY; ABC transporter permease protein K02004 ABC.CD.P; putative ABC transport system permease protein D MGAS9429_Spy1070 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D MGAS9429_Spy0646 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D MGAS9429_Spy1631 ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D MGAS9429_Spy0244 ABC transporter ATP-binding protein K09013 sufC; Fe-S cluster assembly ATP-binding protein D MGAS9429_Spy0042 Na+ driven multidrug efflux pump K26937 dinF; MATE family, multidrug efflux pump D MGAS9429_Spy1182 permease MFS superfamily K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter D MGAS9429_Spy0364 phosphoglycerate transporter protein K02445 glpT; MFS transporter, OPA family, glycerol-3-phosphate transporter D MGAS9429_Spy0410 multidrug resistance efflux pump K08161 mdtG; MFS transporter, DHA1 family, multidrug resistance protein D MGAS9429_Spy1814 lmrP; multidrug resistance protein K08152 lmrP; MFS transporter, DHA1 family, multidrug resistance protein B D MGAS9429_Spy0465 multidrug resistance protein B K18926 lmrB; MFS transporter, DHA2 family, lincomycin resistance protein D MGAS9429_Spy1167 pstI; phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D MGAS9429_Spy1168 ptsH; phosphocarrier protein HPr K02784 ptsH; phosphocarrier protein HPr D MGAS9429_Spy1693 PTS system, glucose-specific IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208] D MGAS9429_Spy1546 scrA; PTS system, sucrose-specific IIABC component K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D MGAS9429_Spy0467 PTS system, beta-glucoside-specific IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D MGAS9429_Spy1795 PTS system, trehalose-specific IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D MGAS9429_Spy0717 fruA; PTS system, fructose-specific IIABC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D MGAS9429_Spy1637 lacF; PTS system, lactose-specific IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D MGAS9429_Spy1636 lacE; PTS system, lactose-specific IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D MGAS9429_Spy1756 PTS system, cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D MGAS9429_Spy1124 PTS system, cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D MGAS9429_Spy1125 PTS system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D MGAS9429_Spy1755 PTS system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D MGAS9429_Spy1754 PTS system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component D MGAS9429_Spy1122 PTS system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component D MGAS9429_Spy1404 PTS system, galactose-specific IIA component K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204] D MGAS9429_Spy1403 PTS system, galactose-specific IIB component K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204] D MGAS9429_Spy1402 PTS system, galactose-specific IIC component K20114 gatC; galactose PTS system EIIC component D MGAS9429_Spy1481 manL; PTS system, mannose-specific IIAB component K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D MGAS9429_Spy0897 PTS system, mannose/fructose family IIA component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D MGAS9429_Spy0899 ptsC; PTS system, mannose/fructose family IIC component K02795 manY; mannose PTS system EIIC component D MGAS9429_Spy1482 manM; PTS system, mannose-specific IIC component K02795 manY; mannose PTS system EIIC component D MGAS9429_Spy0900 ptsD; PTS system, mannose/fructose family IID component K02796 manZ; mannose PTS system EIID component D MGAS9429_Spy1483 manN; PTS system, mannose-specific IID component K02796 manZ; mannose PTS system EIID component D MGAS9429_Spy0898 ptsB; PTS system, mannose/fructose family IIB component K19507 gfrB; fructoselysine/glucoselysine PTS system EIIB component [EC:2.7.1.-] D MGAS9429_Spy0514 PTS system, N-acetylgalactosamine-specific IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-] D MGAS9429_Spy0512 agaV; PTS system, N-acetylgalactosamine-specific IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-] D MGAS9429_Spy0511 PTS system, N-acetylgalactosamine-specific IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component D MGAS9429_Spy0510 agaD; PTS system, N-acetylgalactosamine-specific IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component D MGAS9429_Spy0152 PTS system, 3-keto-L-gulonate specific IIA component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D MGAS9429_Spy1665 transcription antiterminator, BglG family K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D MGAS9429_Spy0151 PTS system, 3-keto-L-gulonate specific IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D MGAS9429_Spy1664 PTS system, IIB component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D MGAS9429_Spy0150 PTS system, 3-keto-L-gulonate specific IIC component K03475 ulaA; ascorbate PTS system EIIC component D MGAS9429_Spy1663 putative transport protein sgaT K03475 ulaA; ascorbate PTS system EIIC component D MGAS9429_Spy1377 glpF; glycerol uptake facilitator protein K02440 glpF; glycerol uptake facilitator D MGAS9429_Spy1578 glpF2; aquaporin K02440 glpF; glycerol uptake facilitator D MGAS9429_Spy0775 glutathione S-transferase K00799 GST; glutathione S-transferase [EC:2.5.1.18] D MGAS9429_Spy1208 formate transporter K21993 fdhC; formate transporter D MGAS9429_Spy0652 mscL; large-conductance mechanosensitive channel K03282 mscL; large conductance mechanosensitive channel D MGAS9429_Spy1616 mechanosensitive ion channel K22044 ybiO; moderate conductance mechanosensitive channel D MGAS9429_Spy1556 corA; magnesium and cobalt transport protein K03284 corA; magnesium transporter D MGAS9429_Spy0316 hlyX; magnesium and cobalt efflux protein K03699 tlyC; magnesium and cobalt exporter, CNNM family D MGAS9429_Spy1428 phage protein K21449 ata; trimeric autotransporter adhesin D MGAS9429_Spy0708 czcD; cobalt-zinc-cadmium resistance protein K16264 czcD; cobalt-zinc-cadmium efflux system protein D MGAS9429_Spy1867 glucose uptake family protein K05340 glcU; glucose uptake protein D MGAS9429_Spy0274 serine/threonine sodium symporter K07862 sstT; serine/threonine transporter D MGAS9429_Spy0276 potassium uptake protein K03498 trkH; trk/ktr system potassium uptake protein D MGAS9429_Spy0275 potassium uptake protein K03499 trkA; trk/ktr system potassium uptake protein D MGAS9429_Spy0695 pyrP; uracil permease K02824 uraA; uracil permease D MGAS9429_Spy0976 xanthine permease K16169 pbuX; xanthine permease D MGAS9429_Spy1479 guanine-hypoxanthine permease K06901 pbuG; adenine/guanine/hypoxanthine permease D MGAS9429_Spy0955 chloride channel protein K03281 clcA; chloride channel protein, CIC family D MGAS9429_Spy1172 chloride channel protein K03281 clcA; chloride channel protein, CIC family D MGAS9429_Spy0603 chloride channel protein K03281 clcA; chloride channel protein, CIC family D MGAS9429_Spy1389 sodium-dependent phosphate transporter K03324 yjbB; phosphate:Na+ symporter D MGAS9429_Spy1199 kup system potassium uptake protein K03549 kup; KUP system potassium uptake protein D MGAS9429_Spy0312 riboflavin transporter K23675 fmnP; riboflavin transporter D MGAS9429_Spy0489 thiamine transporter K16789 thiT; thiamine transporter D MGAS9429_Spy1209 hypothetical protein K16788 niaX; niacin transporter D MGAS9429_Spy0496 ftsW; cell division protein K03588 ftsW; cell division protein FtsW D MGAS9429_Spy1011 oadA1; Na+ transporting oxaloacetate decarboxylase alpha chain K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] D MGAS9429_Spy1278 ccdA; cytochrome c-type biogenesis protein K06196 ccdA; cytochrome c-type biogenesis protein D MGAS9429_Spy1733 HlyD family secretion protein K24950 yknX; membrane fusion protein, antimicrobial resistance system D MGAS9429_Spy0700 hlyD family secretion protein K24950 yknX; membrane fusion protein, antimicrobial resistance system D MGAS9429_Spy1129 nicotinamide mononucleotide transporter K03811 pnuC; nicotinamide mononucleotide transporter C 02044 Secretion system [BR:spk02044] D MGAS9429_Spy1241 integral membrane protein K02221 yggT; YggT family protein D MGAS9429_Spy1195 COME operon protein 1 K02237 comEA; competence protein ComEA D MGAS9429_Spy1552 comEB; comE operon protein 2 K01493 comEB; dCMP deaminase [EC:3.5.4.12] D MGAS9429_Spy1194 comEC; COME operon protein 3 K02238 comEC; competence protein ComEC D MGAS9429_Spy1322 comFA; COMF operon protein 1 K02240 comFA; competence protein ComFA D MGAS9429_Spy1321 comFC; COMF operon protein 3 K02242 comFC; competence protein ComFC D MGAS9429_Spy0087 comYA; ComG operon protein 1 K02243 comGA; competence protein ComGA D MGAS9429_Spy0088 comYB; ComG operon protein 2 K02244 comGB; competence protein ComGB D MGAS9429_Spy0089 comYC; ComG operon protein 3 K02245 comGC; competence protein ComGC D MGAS9429_Spy0090 ComG operon protein 4 K02246 comGD; competence protein ComGD D MGAS9429_Spy0092 comYD; ComG operon protein 6 K02248 comGF; competence protein ComGF D MGAS9429_Spy1255 type 4 prepilin peptidase K02236 comC; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D MGAS9429_Spy1538 secA; protein translocase subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D MGAS9429_Spy1761 secE; protein translocase subunit K03073 secE; preprotein translocase subunit SecE D MGAS9429_Spy0412 secG; protein translocase subunit K03075 secG; preprotein translocase subunit SecG D MGAS9429_Spy0064 secY; protein translocase subunit K03076 secY; preprotein translocase subunit SecY D MGAS9429_Spy1017 ffh; signal recognition particle subunit FFH/SRP54 K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D MGAS9429_Spy0464 ftsY; cell division protein K03110 ftsY; fused signal recognition particle receptor D MGAS9429_Spy1679 yajC; protein translocase subunit K03210 yajC; preprotein translocase subunit YajC D MGAS9429_Spy0209 60 kDa inner membrane protein YIDC K03217 yidC; YidC/Oxa1 family membrane protein insertase D MGAS9429_Spy0295 60 kDa inner membrane protein YIDC K03217 yidC; YidC/Oxa1 family membrane protein insertase C 02042 Bacterial toxins [BR:spk02042] D MGAS9429_Spy0354 spyA; C3 family ADP-ribosyltransferase K11044 spyA; C3 family ADP-ribosyltransferase [EC:2.4.2.-] D MGAS9429_Spy0777 transporter K11041 eta; exfoliative toxin A/B D MGAS9429_Spy0143 slo; streptolysin O K11031 slo; thiol-activated cytolysin D MGAS9429_Spy0316 hlyX; magnesium and cobalt efflux protein K03699 tlyC; magnesium and cobalt exporter, CNNM family D MGAS9429_Spy1085 cfa; cAMP factor K11045 cfa; cAMP factor D MGAS9429_Spy0614 sagA; streptolysin S precursor K11046 sagA; streptolysin S associated protein D MGAS9429_Spy0998 conserved membrane protein K11068 hlyIII; hemolysin III D MGAS9429_Spy0850 speA2; enterotoxin K11040 se; staphylococcal enterotoxin D MGAS9429_Spy0851 enterotoxin K11040 se; staphylococcal enterotoxin D MGAS9429_Spy1708 smeZ; enterotoxin K11040 se; staphylococcal enterotoxin D MGAS9429_Spy0184 speG; enterotoxin K11040 se; staphylococcal enterotoxin D MGAS9429_Spy0593 speC; enterotoxin K11040 se; staphylococcal enterotoxin D MGAS9429_Spy0586 hyaluronoglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] D MGAS9429_Spy1308 hyl; hyaluronoglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] C 02022 Two-component system [BR:spk02022] D MGAS9429_Spy0435 vicK; two-component sensor histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] D MGAS9429_Spy0434 vicR; two-component response regulator K07668 vicR; two-component system, OmpR family, response regulator VicR D MGAS9429_Spy1050 ciaH; sensor protein K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D MGAS9429_Spy1051 ciaR; transcriptional regulatory protein K14983 ciaR; two-component system, OmpR family, response regulator CiaR D MGAS9429_Spy0283 covS; transmembrane histidine kinase K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3] D MGAS9429_Spy0282 covR; response regulator K18941 arlR; two-component system, OmpR family, response regulator ArlR D MGAS9429_Spy1729 ihk; two-component system histidine kinase K18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3] D MGAS9429_Spy1730 irr; two-component response regulator K18987 irr; two-component system, OmpR family, response regulator Irr D MGAS9429_Spy0921 srtK; lantibiotic biosynthesis sensor protein K20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3] D MGAS9429_Spy0920 srtR; lantibiotic biosynthesis two-component response regulator K20488 nisR; two-component system, OmpR family, lantibiotic biosynthesis response regulator NisR/SpaR D MGAS9429_Spy1328 yvqE; two-component sensor protein K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3] D MGAS9429_Spy1327 yvqC; two-component response regulator K11618 liaR; two-component system, NarL family, response regulator LiaR D MGAS9429_Spy1629 sensory transduction protein kinase K14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK D MGAS9429_Spy1628 salR; transcriptional regulatory protein K14989 salR; two-component system, NarL family, secretion system response regulator SalR D MGAS9429_Spy0950 dpiB; sensor kinase K02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3] D MGAS9429_Spy0949 dpiA; transcriptional regulatory protein K02475 K02475; two-component system, CitB family, response regulator D MGAS9429_Spy1312 rocA; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D MGAS9429_Spy0205 fasB; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D MGAS9429_Spy0206 fasC; sensory transduction protein kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D MGAS9429_Spy0207 fasA; response regulator K07707 agrA; two-component system, LytTR family, response regulator AgrA D MGAS9429_Spy1300 two-component sensor kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D MGAS9429_Spy1274 two-component sensor kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D MGAS9429_Spy1299 two-component response regulator K07720 yesN; two-component system, response regulator YesN D MGAS9429_Spy0902 two-component response regulator K07720 yesN; two-component system, response regulator YesN C 02035 Bacterial motility proteins [BR:spk02035] D MGAS9429_Spy0762 cystine-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein D MGAS9429_Spy0269 ABC transporter substrate-binding protein K02424 tcyA; L-cystine transport system substrate-binding protein C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:spk04812] D MGAS9429_Spy1244 ftsZ; cell division protein K03531 ftsZ; cell division protein FtsZ D MGAS9429_Spy1245 ftsA; cell division protein K03590 ftsA; cell division protein FtsA D MGAS9429_Spy1878 parB; chromosome partitioning protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein C 04147 Exosome [BR:spk04147] D MGAS9429_Spy0609 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D MGAS9429_Spy0235 plr; glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D MGAS9429_Spy1604 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D MGAS9429_Spy1092 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D MGAS9429_Spy0374 peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D MGAS9429_Spy1771 groEL; 60 kDa chaperonin GROEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D MGAS9429_Spy1500 dnaK; chaperone protein K04043 dnaK; molecular chaperone DnaK D MGAS9429_Spy0187 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D MGAS9429_Spy1868 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D MGAS9429_Spy0498 translation elongation factor Tu (EF-TU) K02358 tuf; elongation factor Tu D MGAS9429_Spy1474 hit; adenosine 5'-monophosphoramidase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D MGAS9429_Spy0991 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D MGAS9429_Spy0432 long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D MGAS9429_Spy0431 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0121 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy1339 atoB; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D MGAS9429_Spy0065 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D MGAS9429_Spy0786 apt; adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D MGAS9429_Spy1379 glpK; glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D MGAS9429_Spy1601 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D MGAS9429_Spy0027 phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D MGAS9429_Spy0869 acoL; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D MGAS9429_Spy0499 tpi; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D MGAS9429_Spy1212 gpmA; phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] C 02048 Prokaryotic defense system [BR:spk02048] D MGAS9429_Spy1280 hypothetical protein K15342 cas1; CRISP-associated protein Cas1 D MGAS9429_Spy0886 hypothetical cytosolic protein K15342 cas1; CRISP-associated protein Cas1 D MGAS9429_Spy0887 hypothetical cytosolic protein K09951 cas2; CRISPR-associated protein Cas2 D MGAS9429_Spy1279 hypothetical cytosolic protein K09951 cas2; CRISPR-associated protein Cas2 D MGAS9429_Spy1285 ATP-dependent RNA helicase K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] D MGAS9429_Spy1281 hypothetical protein K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] D MGAS9429_Spy1283 hypothetical protein K19117 csd1; CRISPR-associated protein Csd1 D MGAS9429_Spy1282 hypothetical cytosolic protein K19118 csd2; CRISPR-associated protein Csd2 D MGAS9429_Spy1284 hypothetical protein K19119 cas5d; CRISPR-associated protein Cas5d D MGAS9429_Spy0885 hypothetical cytosolic protein K09952 csn1; CRISPR-associated endonuclease Csn1 [EC:3.1.-.-] D MGAS9429_Spy0888 hypothetical protein K19137 csn2; CRISPR-associated protein Csn2 D MGAS9429_Spy1624 hsdR; type I restriction-modification system restriction subunit K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D MGAS9429_Spy1625 hsdS; type I restriction-modification system specificity subunit K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D MGAS9429_Spy1626 hsdM; type I restriction-modification system methylation subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D MGAS9429_Spy1446 adenine-specific methyltransferase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] D MGAS9429_Spy0094 adenine-specific methyltransferase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] D MGAS9429_Spy0915 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D MGAS9429_Spy0566 phage endonuclease K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] D MGAS9429_Spy0455 plasmid stabilization system antitoxin protein K07473 dinJ; DNA-damage-inducible protein J D MGAS9429_Spy0456 plasmid stabilization system toxin protein K19092 parE1_3_4; toxin ParE1/3/4 D MGAS9429_Spy0919 srtI; relaxase K21498 higA-1; antitoxin HigA-1 D MGAS9429_Spy1244 ftsZ; cell division protein K03531 ftsZ; cell division protein FtsZ D MGAS9429_Spy0768 parC; topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D MGAS9429_Spy0767 parE; topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D MGAS9429_Spy0685 nifS1; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D MGAS9429_Spy0963 nifS2; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels [BR:spk04040] C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules [BR:spk04090] C 01504 Antimicrobial resistance genes [BR:spk01504] D MGAS9429_Spy1504 D-alanyl-D-alanine metallocarboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D MGAS9429_Spy1115 dltA; D-alanine-activating enzyme K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D MGAS9429_Spy1114 protein DltB K03739 dltB; membrane protein involved in D-alanine export D MGAS9429_Spy1113 D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D MGAS9429_Spy1112 dltD; protein dltD precursor K03740 dltD; D-alanine transfer protein C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins [BR:spk00536] D MGAS9429_Spy0586 hyaluronoglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] D MGAS9429_Spy1308 hyl; hyaluronoglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:spk00537] D MGAS9429_Spy0586 hyaluronoglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] D MGAS9429_Spy1308 hyl; hyaluronoglucosaminidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35] D MGAS9429_Spy0141 nga; NAD glycohydrolase K18153 nga; NAD+ glycohydrolase [EC:3.2.2.5] C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:spk03100] D MGAS9429_SpyR0010 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0004 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0007 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyT0001 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D MGAS9429_SpyT0029 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D MGAS9429_SpyT0011 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D MGAS9429_SpyT0057 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D MGAS9429_SpyT0062 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D MGAS9429_SpyT0042 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D MGAS9429_SpyT0048 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D MGAS9429_SpyT0067 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D MGAS9429_SpyT0045 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D MGAS9429_SpyT0044 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D MGAS9429_SpyT0009 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D MGAS9429_SpyT0019 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D MGAS9429_SpyT0060 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D MGAS9429_SpyT0065 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D MGAS9429_SpyT0061 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D MGAS9429_SpyT0043 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D MGAS9429_SpyT0003 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D MGAS9429_SpyT0055 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D MGAS9429_SpyT0013 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D MGAS9429_SpyT0064 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D MGAS9429_SpyT0047 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D MGAS9429_SpyT0040 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D MGAS9429_SpyT0033 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D MGAS9429_SpyT0066 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D MGAS9429_SpyT0050 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D MGAS9429_SpyT0026 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D MGAS9429_SpyT0031 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D MGAS9429_SpyT0007 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D MGAS9429_SpyT0017 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D MGAS9429_SpyT0039 tRNA-His K14226 tRNA-His; tRNA His D MGAS9429_SpyT0027 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D MGAS9429_SpyT0051 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D MGAS9429_SpyT0032 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D MGAS9429_SpyT0008 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D MGAS9429_SpyT0018 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D MGAS9429_SpyT0041 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D MGAS9429_SpyT0005 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D MGAS9429_SpyT0053 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D MGAS9429_SpyT0015 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D MGAS9429_SpyT0059 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D MGAS9429_SpyT0004 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D MGAS9429_SpyT0054 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D MGAS9429_SpyT0014 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D MGAS9429_SpyT0063 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D MGAS9429_SpyT0021 tRNA-Met K14230 tRNA-Met; tRNA Met D MGAS9429_SpyT0022 tRNA-Met K14230 tRNA-Met; tRNA Met D MGAS9429_SpyT0024 tRNA-Met K14230 tRNA-Met; tRNA Met D MGAS9429_SpyT0035 tRNA-Met K14230 tRNA-Met; tRNA Met D MGAS9429_SpyT0025 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D MGAS9429_SpyT0036 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D MGAS9429_SpyT0010 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D MGAS9429_SpyT0020 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D MGAS9429_SpyT0023 pseudogene K14233 tRNA-Ser; tRNA Ser D MGAS9429_SpyT0034 pseudogene K14233 tRNA-Ser; tRNA Ser D MGAS9429_SpyT0058 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D MGAS9429_SpyT0028 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D MGAS9429_SpyT0049 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D MGAS9429_SpyT0006 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D MGAS9429_SpyT0016 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D MGAS9429_SpyT0052 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D MGAS9429_SpyT0038 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D MGAS9429_SpyT0037 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D MGAS9429_SpyT0046 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D MGAS9429_SpyT0002 tRNA-Val K14237 tRNA-Val; tRNA Val D MGAS9429_SpyT0056 tRNA-Val K14237 tRNA-Val; tRNA Val D MGAS9429_SpyT0030 tRNA-Val K14237 tRNA-Val; tRNA Val D MGAS9429_SpyT0012 tRNA-Val K14237 tRNA-Val; tRNA Val D MGAS9429_SpyR0015 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0018 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0001 16S small subunit ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D MGAS9429_SpyR0002 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0011 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0005 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0008 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0017 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0014 23S large subunit ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D MGAS9429_SpyR0003 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0009 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0006 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0012 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0016 5S RNA K01985 5SrRNA; 5S ribosomal RNA D MGAS9429_SpyR0013 5S RNA K01985 5SrRNA; 5S ribosomal RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D MGAS9429_Spy0515 idnO; 2-deoxy-D-gluconate 3-dehydrogenase K00046 idnO; gluconate 5-dehydrogenase [EC:1.1.1.69] D MGAS9429_Spy0343 lctO; L-lactate oxidase K10530 lctO; L-lactate oxidase [EC:1.1.3.2] D MGAS9429_Spy1779 ahpF; peroxiredoxin reductase (NAD(P)H) K03387 ahpF; NADH-dependent peroxiredoxin subunit F [EC:1.8.1.-] D MGAS9429_Spy0382 msrA2; peptide methionine sulfoxide reductase K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D MGAS9429_Spy1276 msrA; peptide methionine sulfoxide reductase K12267 msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12] D MGAS9429_Spy0895 msrB; peptide methionine sulfoxide reductase msrB K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] D MGAS9429_Spy1778 ahpC; peroxiredoxin K24119 ahpC; NADH-dependent peroxiredoxin subunit C [EC:1.11.1.26] D MGAS9429_Spy0712 trxB; thioredoxin reductase K21567 fnr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D MGAS9429_Spy0753 arsC; arsenate reductase K00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1] D MGAS9429_Spy1800 nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein K04068 nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4] D MGAS9429_Spy1759 pyruvate formate-lyase activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D MGAS9429_Spy0317 pflC; pyruvate formate-lyase activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D MGAS9429_Spy1347 methyltransferase K07444 ypsC; putative N6-adenine-specific DNA methylase [EC:2.1.1.-] D MGAS9429_Spy0415 glutaminyl-peptide cyclotransferase K22757 QCT; glutaminyl-peptide cyclotransferase [EC:2.3.2.5] D MGAS9429_Spy0446 glycosyltransferase involved in cell wall biogenesis K21349 ggs; glucosylglycerate synthase [EC:2.4.1.268] D MGAS9429_Spy0476 lgt; prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145] D MGAS9429_Spy0977 apbE; iron-sulfur cluster assembly/repair protein K03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180] D MGAS9429_Spy1607 dihydroxyacetone kinase family protein K07030 fakA; fatty acid kinase [EC:2.7.2.18] D MGAS9429_Spy1452 phage-related DNA polymerase K02334 dpo; DNA polymerase bacteriophage-type [EC:2.7.7.7] D MGAS9429_Spy0875 hypothetical membrane spanning protein K18672 dacA; diadenylate cyclase [EC:2.7.7.85] D MGAS9429_Spy0475 ptsK; HPR(SER) kinase K06023 hprK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-] D MGAS9429_Spy0862 estA; acetyl esterase K03930 estA; putative tributyrin esterase [EC:3.1.1.-] D MGAS9429_Spy0259 putative lipase K07015 yqeG; putative phosphatase [EC:3.1.3.-] D MGAS9429_Spy1848 phosphoesterase, DHH family protein K22927 gdpP; cyclic-di-AMP phosphodiesterase [EC:3.1.4.59] D MGAS9429_Spy0221 tatD; DNase, TatD family K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D MGAS9429_Spy0222 ribonuclease M5 K05985 rnmV; ribonuclease M5 [EC:3.1.26.8] D MGAS9429_Spy1684 dexB; glucan 1,6-alpha-glucosidase K01215 dexB; glucan 1,6-alpha-glucosidase [EC:3.2.1.70] D MGAS9429_Spy0513 unsaturated glucuronyl hydrolase K18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180] D MGAS9429_Spy0249 D-alanyl-D-alanine serine-type carboxypeptidase K01286 E3.4.16.4; D-alanyl-D-alanine carboxypeptidase [EC:3.4.16.4] D MGAS9429_Spy1687 ska; streptokinase K14745 ska; streptokinase A [EC:3.4.-.-] D MGAS9429_Spy0732 fms; peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D MGAS9429_Spy1670 def; peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D MGAS9429_Spy1165 peptidoglycan N-acetylglucosamine deacetylase K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104] D MGAS9429_Spy0125 translation initiation inhibitor K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10] D MGAS9429_Spy0385 myosin-crossreactive antigen K10254 ohyA; oleate hydratase [EC:4.2.1.53] D MGAS9429_Spy0871 hylA; hyaluronate lyase precursor K01727 hysA; hyaluronate lyase [EC:4.2.2.1] D MGAS9429_Spy0507 pacL; calcium-transporting ATPase K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10] D MGAS9429_Spy1216 lead, cadmium, zinc and mercury transporting ATPase K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21] C 99981 Carbohydrate metabolism C 99982 Energy metabolism D MGAS9429_Spy0671 ferredoxin K05337 fer; ferredoxin D MGAS9429_Spy0247 nifU; IscU protein K04488 iscU; nitrogen fixation protein NifU and related proteins C 99983 Lipid metabolism D MGAS9429_Spy0727 DegV family protein K25232 fakB; fatty acid kinase fatty acid binding subunit D MGAS9429_Spy1220 DegV family protein K25232 fakB; fatty acid kinase fatty acid binding subunit C 99984 Nucleotide metabolism D MGAS9429_Spy0351 nrdI; NrdI protein K03647 nrdI; protein involved in ribonucleotide reduction D MGAS9429_Spy1691 nrdI protein K03647 nrdI; protein involved in ribonucleotide reduction D MGAS9429_Spy1747 spd; deoxyribonuclease precursor K15051 endA; DNA-entry nuclease D MGAS9429_Spy0640 endA; DNA-entry nuclease K15051 endA; DNA-entry nuclease D MGAS9429_Spy1417 sdaD2; deoxyribonuclease precursor K15051 endA; DNA-entry nuclease D MGAS9429_Spy0594 spd1; streptodornase K15051 endA; DNA-entry nuclease C 99985 Amino acid metabolism D MGAS9429_Spy0994 glyoxalase family protein K08234 yaeR; glyoxylase I family protein D MGAS9429_Spy1243 pyridoxal-5'-phosphate family protein K06997 yggS; PLP dependent protein C 99986 Glycan metabolism C 99987 Cofactor metabolism C 99988 Secondary metabolism C 99999 Others B B 09192 Unclassified: genetic information processing C 99973 Transcription D MGAS9429_Spy1776 csp; cold shock protein K03704 cspA; cold shock protein D MGAS9429_Spy0799 phage antirepressor protein K07741 antB; anti-repressor protein D MGAS9429_Spy1063 arsenate reductase family protein K16509 spxA; regulatory protein spx D MGAS9429_Spy1809 arsenate reductase family protein K16509 spxA; regulatory protein spx D MGAS9429_Spy0472 transcription accessory protein (S1 RNA binding domain) K06959 tex; protein Tex C 99974 Translation D MGAS9429_Spy1325 S1-type RNA-binding domain K07570 GSP13; general stress protein 13 C 99975 Protein processing D MGAS9429_Spy1615 ropA; trigger factor, ppiase K03545 tig; trigger factor D MGAS9429_Spy0414 ssrA-binding protein K03664 smpB; SsrA-binding protein D MGAS9429_Spy1169 nrdH; glutaredoxin K06191 nrdH; glutaredoxin-like protein NrdH D MGAS9429_Spy0241 mecA; negative regulator of genetic competence K16511 mecA1_2; adapter protein MecA 1/2 C 99976 Replication and repair D MGAS9429_Spy0959 radC; DNA repair protein K03630 radC; DNA repair protein RadC D MGAS9429_Spy0228 RmuC family protein K09760 rmuC; DNA recombination protein RmuC D MGAS9429_Spy1198 hypothetical protein with endo/excinuclease domain K07461 K07461; putative endonuclease D MGAS9429_Spy1002 smf; DNA processing protein K04096 smf; DNA processing protein D MGAS9429_Spy0787 dnaD; DNA replication protein K02086 dnaD; DNA replication protein D MGAS9429_Spy0806 DNA replication protein K02086 dnaD; DNA replication protein D MGAS9429_Spy0823 phage terminase small subunit K07474 xtmA; phage terminase small subunit D MGAS9429_Spy1443 phage terminase small subunit K07474 xtmA; phage terminase small subunit D MGAS9429_Spy0824 terminase large subunit K06909 xtmB; phage terminase large subunit D MGAS9429_Spy1442 terminase large subunit K06909 xtmB; phage terminase large subunit D MGAS9429_Spy1704 ATPase, AAA family K07478 ycaJ; putative ATPase D MGAS9429_Spy1451 DNA primase K06919 K06919; putative DNA primase/helicase D MGAS9429_Spy0551 DNA primase K06919 K06919; putative DNA primase/helicase D MGAS9429_Spy1318 transposase K18320 IS15; transposase, IS6 family D MGAS9429_Spy1109 transposase K07482 K07482; transposase, IS30 family D MGAS9429_Spy1133 transposase K07483 K07483; transposase D MGAS9429_Spy0174 transposase K07483 K07483; transposase D MGAS9429_Spy1173 transposase K07483 K07483; transposase D MGAS9429_Spy0170 transposase K07483 K07483; transposase D MGAS9429_Spy0461 transposase K07483 K07483; transposase D MGAS9429_Spy0610 transposase K07486 K07486; transposase D MGAS9429_Spy0393 transposase K07493 K07493; putative transposase D MGAS9429_Spy0173 transposase K07497 K07497; putative transposase D MGAS9429_Spy0169 transposase K07497 K07497; putative transposase D MGAS9429_Spy1134 transposase K07497 K07497; putative transposase D MGAS9429_Spy1174 transposase K07497 K07497; putative transposase D MGAS9429_Spy0459 transposase K07497 K07497; putative transposase C 99979 Viral proteins C 99998 Others D MGAS9429_Spy1585 hypothetical cytosolic protein K09747 ebfC; nucleoid-associated protein EbfC B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D MGAS9429_Spy1355 amino acid permease K03293 TC.AAT; amino acid transporter, AAT family D MGAS9429_Spy0014 amino acid permease K03294 TC.APA; basic amino acid/polyamine antiporter, APA family D MGAS9429_Spy1082 Na(+)-linked D-alanine glycine permease K03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family D MGAS9429_Spy0273 braB; branched-chain amino acid transport system carrier protein K03311 TC.LIVCS; branched-chain amino acid:cation transporter, LIVCS family D MGAS9429_Spy1591 nupC; nucleoside permease K03317 TC.CNT; concentrative nucleoside transporter, CNT family C 99978 Cell growth D MGAS9429_Spy1346 hypothetical protein K20073 mapZ; mid-cell-anchored protein Z D MGAS9429_Spy0210 jag protein K06346 jag; spoIIIJ-associated protein D MGAS9429_Spy0533 site-specific recombinase K06400 spoIVCA; site-specific DNA recombinase C 99993 Cell motility C 99995 Signaling proteins D MGAS9429_Spy1250 typA; GTP-binding protein K06207 typA; GTP-binding protein D MGAS9429_Spy0386 phoH; PhoH protein K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins C 99992 Structural proteins D MGAS9429_Spy0490 N-acetylmuramoyl-L-alanine amidase K07273 acm; lysozyme C 99994 Others D MGAS9429_Spy1054 phoU; phosphate transport system protein K02039 phoU; phosphate transport system protein D MGAS9429_Spy0340 cutC; copper homeostasis protein K06201 cutC; copper homeostasis protein B B 09194 Poorly characterized C 99996 General function prediction only D MGAS9429_Spy1802 NAD-dependent oxidoreductase K03810 mviM; virulence factor D MGAS9429_Spy1184 putative competence protein/transcription factor K06198 coiA; competence protein CoiA D MGAS9429_Spy0102 tRNA binding domain protein K06878 K06878; tRNA-binding protein D MGAS9429_Spy0486 hydrolase (HAD superfamily) K07025 K07025; putative hydrolase of the HAD superfamily D MGAS9429_Spy0248 ABC transporter-associated protein K09014 sufB; Fe-S cluster assembly protein SufB D MGAS9429_Spy0245 SufD protein K09015 sufD; Fe-S cluster assembly protein SufD D MGAS9429_Spy1146 ribonuclease BN K07058 K07058; membrane protein D MGAS9429_Spy0773 rhodanese-related sulfurtransferases K07146 K07146; UPF0176 protein D MGAS9429_Spy0278 lemA; LemA protein K03744 lemA; LemA protein D MGAS9429_Spy0473 metallopeptidase, SprT family K03095 sprL; SprT-like protein D MGAS9429_Spy1842 phage infection protein K01421 yhgE; putative membrane protein D MGAS9429_Spy1836 integral membrane protein K08974 K08974; putative membrane protein D MGAS9429_Spy0469 hypothetical membrane spanning protein K08986 ycgQ; putative membrane protein D MGAS9429_Spy1089 PhnA protein K06193 phnA; protein PhnA C 99997 Function unknown D MGAS9429_Spy0506 dGTP triphosphohydrolase K06885 K06885; uncharacterized protein D MGAS9429_Spy1611 alpha/beta hydrolase K06889 K06889; uncharacterized protein D MGAS9429_Spy0299 integral membrane protein K06890 K06890; uncharacterized protein D MGAS9429_Spy0162 coA binding protein K06929 K06929; uncharacterized protein D MGAS9429_Spy0298 hydrolase (HAD superfamily) K06950 K06950; uncharacterized protein D MGAS9429_Spy0705 RNA binding protein K06960 K06960; uncharacterized protein D MGAS9429_Spy1652 hypothetical cytosolic protein K06962 K06962; uncharacterized protein D MGAS9429_Spy0625 endonuclease/exonuclease/phosphatase family protein K07004 K07004; uncharacterized protein D MGAS9429_Spy0707 hypothetical cytosolic protein K07006 K07006; uncharacterized protein D MGAS9429_Spy0713 hypothetical membrane spanning protein K07035 K07035; uncharacterized protein D MGAS9429_Spy1006 hypothetical membrane spanning protein K07035 K07035; uncharacterized protein D MGAS9429_Spy0647 neutral zinc metallopeptidase family K07054 K07054; uncharacterized protein D MGAS9429_Spy0470 hypothetical membrane spanning protein K07089 K07089; uncharacterized protein D MGAS9429_Spy0304 putative phosphoesterase K07095 K07095; uncharacterized protein D MGAS9429_Spy1211 transcriptional regulator, biotin repressor family K07105 K07105; uncharacterized protein D MGAS9429_Spy0783 short chain dehydrogenase K07124 K07124; uncharacterized protein D MGAS9429_Spy0314 radical SAM superfamily protein K07139 K07139; uncharacterized protein D MGAS9429_Spy0310 hypothetical cytosolic protein K08998 K08998; uncharacterized protein D MGAS9429_Spy1310 hypothetical protein K09704 K09704; uncharacterized protein D MGAS9429_Spy1018 ylxM; signal recognition particle associated protein K09787 K09787; uncharacterized protein D MGAS9429_Spy0381 S1 RNA binding domain K00243 K00243; uncharacterized protein D MGAS9429_Spy1799 yaaA; hypothetical cytosolic protein K09861 K09861; uncharacterized protein D MGAS9429_Spy1127 outer surface protein K09963 K09963; uncharacterized protein D MGAS9429_Spy0300 hypothetical exported protein K09976 K09976; uncharacterized protein D MGAS9429_Spy0689 hypothetical ribosome-associated protein K07584 ysxB; uncharacterized protein D MGAS9429_Spy1315 hypothetical cytosolic protein K07586 ygaC; uncharacterized protein D MGAS9429_Spy1413 hypothetical cytosolic protein K07742 ylxR; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: April 26, 2024