+F Repair protein KO
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DNA Repair and Recombination Proteins - Salmonella enterica subsp. enterica serovar Typhimurium LT2
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D STM1659 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D STM0709 phrB; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E STM2647 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E STM3110 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E STM1453 nth; DNA glycosylase/apyrimidinic (AP) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D STM0137 mutT; 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D STM3731 dut; deoxyuridinetriphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D STM1659 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D STM2265 ada; bifunctional transcriptional regulator/O6-methylguanine-DNA methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D STM0709 phrB; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D STM2264 alkB; alpha-ketoglutarate-dependent dioxygenase AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E STM2647 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E STM3212 mug; double-stranded uracil-DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E STM2124 alkA; DNA-3-methyladenine glycosylase 2 K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E STM3110 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E STM3642 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E STM3726 mutM; DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E STM0728 nei; endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E STM1453 nth; DNA glycosylase/apyrimidinic (AP) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E STM1302 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E STM2203 nfo; deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E STM4168 nfi; endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E STM3042 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E STM2427 lig; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E STM3739 yicF; DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E STM3999 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E STM4254 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E STM0798 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E STM1946 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E STM1309 putative nuclease subunit of the excinuclease complex K05984 cho; excinuclease Cho [EC:3.1.25.-]
E STM3951 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E STM3999 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E STM2427 lig; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E STM3739 yicF; DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F STM4153 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F STM4154 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F STM3415 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F STM3741 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F STM1216 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E STM2909 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E STM4359 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E STM3005 mutH; DNA mismatch repair endonuclease MutH K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E STM2067 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E STM2512 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E STM0424 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
E STM1878 exoX; exodeoxyribonuclease X K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D DNA polymerase III holoenzyme
E STM0231 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E STM3837 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E STM4476 holC; DNA polymerase III, chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E STM0646 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E STM1201 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E STM0264 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E STM0484 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E STM4557 holD; DNA polymerase III subunit psi K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
E STM1876 holE; DNA polymerase III subunit theta K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
E PSLT064 putative inner membrane protein K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
D DNA ligase
E STM2427 lig; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E STM3739 yicF; DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E STM3951 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PSLT066 ssbB; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E STM4256 ssb; ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein
E STM2730 Fels-2 prophage protein K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E STM3484 dam; DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E STM1991 vsr; very short patch repair endonuclease K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E STM2994 recB; exodeoxyribonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E STM2996 recC; exodeoxyribonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E STM2993 recD; exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E STM2829 recA; recombinase RecA K03553 recA; recombination protein RecA
E STM1895 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E STM1894 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E STM1898 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E STM4095 priA; factor Y K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E STM4392 priB; primosomal replication protein N K02686 priB; primosomal replication protein N
E STM0481 priC; primosomal replication protein N K04067 priC; primosomal replication protein N''
E STM4544 dnaT; primosomal protein DnaI K02317 dnaT; DNA replication protein DnaT
E STM2067 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E STM0395 sbcC; exonuclease subunit SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E STM0396 sbcD; exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E STM2829 recA; recombinase RecA K03553 recA; recombination protein RecA
E STM4579 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E STM3836 recF; DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF
E STM3744 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E STM3042 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E STM2579 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E STM0486 recR; recombination protein RecR K06187 recR; recombination protein RecR
E STM2684 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E STM0392 rdgC; recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E STM1895 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E STM1894 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E STM1898 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E STM2938 subtype I-E CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
E STM2223 yejH; putative ATP-dependent helicase K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E STM0395 sbcC; exonuclease subunit SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E STM0396 sbcD; exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F STM2272 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F STM3835 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F STM1714 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F STM4170 hupA; DNA-binding protein K05787 hupA; DNA-binding protein HU-alpha
F STM0451 hupB; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F STM1009 Gifsy-2 prophage exodeoxyribonuclease K10906 recE; exodeoxyribonuclease VIII [EC:3.1.11.-]
F STM2632 Gifsy-1 prophage protein K10906 recE; exodeoxyribonuclease VIII [EC:3.1.11.-]
F STM3042 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F STM2579 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F STM0486 recR; recombination protein RecR K06187 recR; recombination protein RecR
F STM2427 lig; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F STM3739 yicF; DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F STM3385 fis; Fis family transcriptional regulator K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F STM1339 himA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F STM0982 himD; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F STM2067 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F STM3958 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F STM4254 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F STM0798 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F STM1751 hns; transcriptional regulator K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D STM0313 dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D STM1997 umuC; DNA polymerase V subunit UmuC K03502 umuC; DNA polymerase V
D PSLT054 samB; mutagenesis by UV and mutagens; related to umuDC operon K03502 umuC; DNA polymerase V
D STM1998 umuD; DNA polymerase V subunit UmuD K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D PSLT055 samA; mutagenesis by UV and mutagens; related to umuDC operon K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D STM2829 recA; recombinase RecA K03553 recA; recombination protein RecA
D STM4237 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D STM2684 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D STM0097 polB; DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D PSLT066 ssbB; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D STM4256 ssb; ssDNA-binding protein K03111 ssb; single-strand DNA-binding protein
D STM1162 dinI; DNA damage-inducible protein I K12149 dinI; DNA-damage-inducible protein I
D STM2621 Gifsy-1 prophage protein K12149 dinI; DNA-damage-inducible protein I
D STM2828 oraA; recombination regulator RecX K03565 recX; regulatory protein
D PSLT051 samB; putative cytoplasmic protein K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
D STM3508 hypothetical protein K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D STM3912 rep; ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D STM1075 helD; DNA helicase IV K03658 helD; DNA helicase IV [EC:5.6.2.4]
D STM0821 dinG; ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D STM1821 yoaA; ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D STM0137 mutT; 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D STM3731 dut; deoxyuridinetriphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D STM2277 nrdA; ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D STM2807 nrdE; ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D STM2278 nrdB; ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D STM2808 nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024