+D GENES KO #

  KEGG Orthology (KO) - Spirochaeta thermophila DSM 6578

% ! A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:stq00010] D Spith_0651 Glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Spith_2057 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Spith_0248 phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spith_0029 6-phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Spith_0239 phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Spith_1820 diphosphate/fructose-6-phosphate1-phosphotransferase K00895 pfp; diphosphate-dependent phosphofructokinase [EC:2.7.1.90] D Spith_1381 fructose-1,6-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Spith_1006 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Spith_1004 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Spith_1005 Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Spith_0500 phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Spith_2058 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Spith_0102 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Spith_0414 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] D Spith_2010 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Spith_2009 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Spith_2008 catalytic domain-containing protein of components of various dehydrogenase complexes K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Spith_1347 catalytic domain-containing protein of components of various dehydrogenase complexes K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Spith_0736 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spith_1722 pyruvate ferredoxin/flavodoxin oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] D Spith_0238 Aldose 1-epimerase K01785 galM; aldose 1-epimerase [EC:5.1.3.3] D Spith_0242 Aldose 1-epimerase K01785 galM; aldose 1-epimerase [EC:5.1.3.3] D Spith_1237 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Spith_2203 Phosphoenolpyruvate carboxykinase (GTP) K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] C 00020 Citrate cycle (TCA cycle) [PATH:stq00020] D Spith_1196 Citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1] D Spith_2116 aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3] D Spith_1886 isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D Spith_0736 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spith_2105 Fumarate hydratase class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D Spith_2200 biotin/lipoyl attachment domain-containing protein K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1] D Spith_2203 Phosphoenolpyruvate carboxykinase (GTP) K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] D Spith_2010 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Spith_2009 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Spith_2008 catalytic domain-containing protein of components of various dehydrogenase complexes K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Spith_1347 catalytic domain-containing protein of components of various dehydrogenase complexes K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Spith_1722 pyruvate ferredoxin/flavodoxin oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] C 00030 Pentose phosphate pathway [PATH:stq00030] D Spith_2057 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Spith_2050 glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D Spith_0503 6-phosphogluconolactonase K01057 PGLS; 6-phosphogluconolactonase [EC:3.1.1.31] D Spith_0379 6-phosphogluconate dehydrogenase, decarboxylating K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] D Spith_1725 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D Spith_0122 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D Spith_1726 Ribose-5-phosphate isomerase A K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D Spith_1846 Deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4] D Spith_0408 PfkB domain protein K00852 rbsK; ribokinase [EC:2.7.1.15] D Spith_1237 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Spith_0824 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Spith_0399 KDPG and KHG aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] D Spith_0398 PfkB domain protein K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45] D Spith_2034 MOFRL domain protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D Spith_1381 fructose-1,6-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Spith_0248 phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spith_0029 6-phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Spith_0239 phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Spith_1820 diphosphate/fructose-6-phosphate1-phosphotransferase K00895 pfp; diphosphate-dependent phosphofructokinase [EC:2.7.1.90] C 00040 Pentose and glucuronate interconversions [PATH:stq00040] D Spith_1486 Cupin 2 conserved barrel domain protein K26933 kdgF; unsaturated pyranuronate lyase [EC:4.2.99.25] D Spith_0377 4-deoxy-L-threo-5-hexosulose-uronateketol-isomerase K01815 kduI; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [EC:5.3.1.17] D Spith_0378 2-deoxy-D-gluconate 3-dehydrogenase K00065 kduD; 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase [EC:1.1.1.127] D Spith_1353 glycoside hydrolase family 4 K22933 lplD; galacturan 1,4-alpha-galacturonidase [EC:3.2.1.67] D Spith_0417 Uronate isomerase K01812 uxaC; glucuronate isomerase [EC:5.3.1.12] D Spith_0580 Mannonate dehydratase K01686 uxuA; mannonate dehydratase [EC:4.2.1.8] D Spith_0401 hypothetical protein K21619 uxaE; tagaturonate epimerase [EC:5.1.2.7] D Spith_0616 Alcohol dehydrogenase GroES domain protein K08322 rspB; L-gulonate 5-dehydrogenase [EC:1.1.1.380] D Spith_0011 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Spith_0089 Nucleotidyl transferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Spith_2094 class II aldolase/adducin family protein K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4] D Spith_1725 ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D Spith_2095 L-arabinose isomerase K01804 araA; L-arabinose isomerase [EC:5.3.1.4] D Spith_2096 Ribulokinase K00853 araB; L-ribulokinase [EC:2.7.1.16] D Spith_0123 Carbohydrate kinase, FGGY K00854 xylB; xylulokinase [EC:2.7.1.17] D Spith_0825 Carbohydrate kinase, FGGY K00854 xylB; xylulokinase [EC:2.7.1.17] D Spith_1689 Xylose isomerase K01805 xylA; xylose isomerase [EC:5.3.1.5] D Spith_0427 L-fucose isomerase K01818 fucI; L-fucose/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3] C 00051 Fructose and mannose metabolism [PATH:stq00051] D Spith_1286 glycoside hydrolase family 5 K01218 gmuG; mannan endo-1,4-beta-mannosidase [EC:3.2.1.78] D Spith_0421 PfkB domain protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D Spith_0479 ROK family protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D Spith_1819 mannose-6-phosphate isomerase, class I K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D Spith_0163 Nucleotidyl transferase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D Spith_1623 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47] D Spith_1622 NAD-dependent epimerase/dehydratase K02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271] D Spith_0427 L-fucose isomerase K01818 fucI; L-fucose/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3] D Spith_1333 L-rhamnose isomerase K01813 rhaA; L-rhamnose isomerase [EC:5.3.1.14] D Spith_0248 phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spith_0029 6-phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Spith_0239 phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Spith_1820 diphosphate/fructose-6-phosphate1-phosphotransferase K00895 pfp; diphosphate-dependent phosphofructokinase [EC:2.7.1.90] D Spith_1344 short-chain dehydrogenase/reductase SDR K00068 srlD; sorbitol-6-phosphate 2-dehydrogenase [EC:1.1.1.140] D Spith_1342 Alcohol dehydrogenase zinc-binding domain protein K19956 sorE; L-sorbose 1-phosphate reductase [EC:1.1.1.-] D Spith_1689 Xylose isomerase K01805 xylA; xylose isomerase [EC:5.3.1.5] D Spith_1381 fructose-1,6-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Spith_1006 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 00052 Galactose metabolism [PATH:stq00052] D Spith_0238 Aldose 1-epimerase K01785 galM; aldose 1-epimerase [EC:5.1.3.3] D Spith_0242 Aldose 1-epimerase K01785 galM; aldose 1-epimerase [EC:5.1.3.3] D Spith_0890 GHMP kinase K00849 galK; galactokinase [EC:2.7.1.6] D Spith_0363 galactokinase K00849 galK; galactokinase [EC:2.7.1.6] D Spith_0362 galactose-1-phosphate uridylyltransferase K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12] D Spith_0358 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Spith_1626 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Spith_0089 Nucleotidyl transferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Spith_1237 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Spith_0651 Glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Spith_1935 glycoside hydrolase family 2 sugar binding protein K01190 lacZ; beta-galactosidase [EC:3.2.1.23] D Spith_0357 Glycoside hydrolase family 42 domain protein K12308 bgaB; beta-galactosidase [EC:3.2.1.23] D Spith_0361 glycoside hydrolase clan GH-D K07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22] D Spith_2035 PTS system Galactitol-specific IIC component K02775 gatC; galactitol PTS system EIIC component D Spith_0248 phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spith_0029 6-phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Spith_0239 phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Spith_1044 glycoside hydrolase family 31 K01187 malZ; alpha-glucosidase [EC:3.2.1.20] D Spith_0720 alpha amylase catalytic region K01182 IMA; oligo-1,6-glucosidase [EC:3.2.1.10] C 00053 Ascorbate and aldarate metabolism [PATH:stq00053] D Spith_0011 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Spith_0050 NAD-dependent epimerase/dehydratase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] D Spith_2094 class II aldolase/adducin family protein K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4] C 00500 Starch and sucrose metabolism [PATH:stq00500] D Spith_1044 glycoside hydrolase family 31 K01187 malZ; alpha-glucosidase [EC:3.2.1.20] D Spith_0089 Nucleotidyl transferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Spith_1531 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_0366 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_0766 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_0770 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_1795 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_2148 beta-galactosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] D Spith_0779 glycoside hydrolase family 5 K01179 E3.2.1.4; endoglucanase [EC:3.2.1.4] D Spith_2109 glycoside hydrolase family 5 K01179 E3.2.1.4; endoglucanase [EC:3.2.1.4] D Spith_2107 glycoside hydrolase family 9 K01179 E3.2.1.4; endoglucanase [EC:3.2.1.4] D Spith_1446 glycoside hydrolase family 5 K01179 E3.2.1.4; endoglucanase [EC:3.2.1.4] D Spith_1704 glycoside hydrolase family 9 K01179 E3.2.1.4; endoglucanase [EC:3.2.1.4] D Spith_2108 glycoside hydrolase family 9 K01179 E3.2.1.4; endoglucanase [EC:3.2.1.4] D Spith_2147 glycosyltransferase 36 K00702 E2.4.1.20; cellobiose phosphorylase [EC:2.4.1.20] D Spith_0477 glycosyltransferase 36 K00702 E2.4.1.20; cellobiose phosphorylase [EC:2.4.1.20] D Spith_1410 Nucleotidyl transferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] D Spith_1409 Glycogen synthase K00703 glgA; starch synthase [EC:2.4.1.21] D Spith_0915 Domain of unknown function DUF1957 K16149 K16149; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18] D Spith_0787 alpha-glucan phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1] D Spith_1658 alpha amylase catalytic region K01176 AMY; alpha-amylase [EC:3.2.1.1] D Spith_0720 alpha amylase catalytic region K01182 IMA; oligo-1,6-glucosidase [EC:3.2.1.10] D Spith_1288 glycoside hydrolase family 57 K22451 jgt; 4-alpha-glucanotransferase [EC:2.4.1.25] D Spith_1566 glycoside hydrolase family 65 central catalytic K00691 mapA; maltose phosphorylase [EC:2.4.1.8] D Spith_1564 beta-phosphoglucomutase K01838 pgmB; beta-phosphoglucomutase [EC:5.4.2.6] D Spith_1237 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Spith_0651 Glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Spith_2057 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Spith_0421 PfkB domain protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D Spith_0479 ROK family protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:stq00520] D Spith_0768 glycoside hydrolase family 3 domain protein K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] D Spith_1407 glycoside hydrolase family 3 domain protein K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] D Spith_0246 Glycoside hydrolase, family 20, catalytic core K12373 HEXA_B; hexosaminidase [EC:3.2.1.52] D Spith_0421 PfkB domain protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D Spith_0479 ROK family protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D Spith_0240 sugar isomerase (SIS) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Spith_0173 Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Spith_0051 UDP-N-acetylglucosamine1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D Spith_1868 UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D Spith_0632 oxidoreductase domain protein K13020 wlbA; UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase [EC:1.1.1.335] D Spith_0748 alpha-L-arabinofuranosidase domain protein K01209 abfA; alpha-L-arabinofuranosidase [EC:3.2.1.55] D Spith_0749 alpha-L-arabinofuranosidase domain protein K01209 abfA; alpha-L-arabinofuranosidase [EC:3.2.1.55] D Spith_1893 glycoside hydrolase family 43 K01198 xynB; xylan 1,4-beta-xylosidase [EC:3.2.1.37] D Spith_0651 Glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Spith_1237 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Spith_0089 Nucleotidyl transferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Spith_0011 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Spith_0890 GHMP kinase K00849 galK; galactokinase [EC:2.7.1.6] D Spith_0363 galactokinase K00849 galK; galactokinase [EC:2.7.1.6] D Spith_0362 galactose-1-phosphate uridylyltransferase K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12] D Spith_0358 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Spith_1626 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Spith_0050 NAD-dependent epimerase/dehydratase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] D Spith_2057 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Spith_1819 mannose-6-phosphate isomerase, class I K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D Spith_0163 Nucleotidyl transferase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D Spith_1623 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47] D Spith_1622 NAD-dependent epimerase/dehydratase K02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271] D Spith_1410 Nucleotidyl transferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] C 00620 Pyruvate metabolism [PATH:stq00620] D Spith_1722 pyruvate ferredoxin/flavodoxin oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] D Spith_2010 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Spith_2009 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Spith_2008 catalytic domain-containing protein of components of various dehydrogenase complexes K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Spith_1347 catalytic domain-containing protein of components of various dehydrogenase complexes K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Spith_0736 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spith_1871 Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D Spith_1303 phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D Spith_0102 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Spith_1313 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D Spith_1316 acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D Spith_1315 acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D Spith_1314 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D Spith_2059 Acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] D Spith_0579 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K03778 ldhA; D-lactate dehydrogenase [EC:1.1.1.28] D Spith_1779 beta lactamase like protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D Spith_1730 hypothetical protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D Spith_0637 malic protein NAD-binding protein K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] D Spith_2201 sodium ion-translocating decarboxylase, beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D Spith_2199 oxaloacetate decarboxylase gamma chain K01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma D Spith_2200 biotin/lipoyl attachment domain-containing protein K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1] D Spith_2105 Fumarate hydratase class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D Spith_2203 Phosphoenolpyruvate carboxykinase (GTP) K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] D Spith_0414 pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] D Spith_0967 2-isopropylmalate synthase/homocitrate synthase family protein K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] D Spith_2122 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:stq00630] D Spith_1196 Citrate synthase K01647 CS; citrate synthase [EC:2.3.3.1] D Spith_2116 aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3] D Spith_1815 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18] D Spith_0267 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spith_0158 glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Spith_0736 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spith_0010 Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein D Spith_0730 glycine cleavage H-protein K02437 gcvH; glycine cleavage system H protein D Spith_2034 MOFRL domain protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D Spith_0399 KDPG and KHG aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] D Spith_1716 formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10] C 00640 Propanoate metabolism [PATH:stq00640] D Spith_1871 Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D Spith_1303 phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D Spith_2022 Transketolase domain-containing protein K11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] D Spith_1346 Transketolase central region K11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] D Spith_0736 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spith_1313 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D Spith_1316 acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D Spith_1315 acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D Spith_1314 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D Spith_1897 Methylglyoxal synthase K01734 mgsA; methylglyoxal synthase [EC:4.2.3.3] C 00650 Butanoate metabolism [PATH:stq00650] D Spith_1690 reductase K00209 fabV; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44] D Spith_2201 sodium ion-translocating decarboxylase, beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D Spith_1722 pyruvate ferredoxin/flavodoxin oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] D Spith_1789 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Spith_1790 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] C 00660 C5-Branched dibasic acid metabolism [PATH:stq00660] D Spith_1789 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Spith_1790 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Spith_0111 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Spith_2135 homoaconitate hydratase family protein K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Spith_0112 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Spith_2134 aconitate hydratase domain-containing protein K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Spith_0359 isocitrate/isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] C 00562 Inositol phosphate metabolism [PATH:stq00562] D Spith_0671 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Spith_1006 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:stq00190] D Spith_1511 NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2] D Spith_0638 NADH-quinone oxidoreductase, E subunit K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2] D Spith_0639 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2] D Spith_2033 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9] D Spith_1249 V-type ATP synthase alpha chain K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] D Spith_1248 V-type ATP synthase beta chain K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B D Spith_1247 V-type ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D D Spith_1251 V-type ATPase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E D Spith_1246 V-type ATPase 116 kDa subunit K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I D Spith_1245 hypothetical protein K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K D Spith_2258 polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation in photosynthetic organisms C 00720 Carbon fixation pathways in prokaryotes C 00680 Methane metabolism [PATH:stq00680] D Spith_0158 glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Spith_2034 MOFRL domain protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D Spith_2058 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Spith_1381 fructose-1,6-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D Spith_0248 phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spith_0029 6-phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Spith_0239 phosphofructokinase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] D Spith_1871 Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D Spith_1303 phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D Spith_0500 phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Spith_0137 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Spith_0389 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Spith_0138 Phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Spith_2225 phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein K02203 thrH; phosphoserine / homoserine phosphotransferase [EC:3.1.3.3 2.7.1.39] C 00910 Nitrogen metabolism [PATH:stq00910] D Spith_2065 Hydroxylamine reductase K05601 hcp; hydroxylamine reductase [EC:1.7.99.1] D Spith_0267 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spith_1049 ferredoxin-dependent glutamate synthase K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D Spith_1295 glutamate synthase (NADPH), homotetrameric K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D Spith_1050 glutamate synthase, NADH/NADPH, small subunit K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] C 00920 Sulfur metabolism [PATH:stq00920] D Spith_1677 sulfate adenylyltransferase, large subunit K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25] D Spith_1678 phosphoadenosine phosphosulfate reductase K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4] D Spith_0597 phosphoesterase RecJ domain protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] D Spith_1679 adenylylsulfate reductase, thioredoxin dependent K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] D Spith_1681 nitrite and sulphite reductase 4Fe-4S region K00392 sir; sulfite reductase (ferredoxin) [EC:1.8.7.1] D Spith_0228 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Spith_0866 cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47] D Spith_0886 cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47] D Spith_1383 Homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:stq00061] D Spith_1313 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D Spith_1316 acetyl-CoA carboxylase, biotin carboxyl carrier protein K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D Spith_1315 acetyl-CoA carboxylase, biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D Spith_1314 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D Spith_1094 Acyl carrier protein K02078 acpP; acyl carrier protein D Spith_2198 malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D Spith_0071 3-oxoacyl-(acyl-carrier-protein) synthase 3 K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D Spith_2196 3-oxoacyl-(acyl-carrier-protein) synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D Spith_0387 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spith_1224 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spith_2197 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spith_1749 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spith_1317 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D Spith_1690 reductase K00209 fabV; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44] D Spith_0285 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spith_1318 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spith_1549 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 00062 Fatty acid elongation C 00071 Fatty acid degradation D Spith_0285 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spith_1318 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spith_1549 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism [PATH:stq00561] D Spith_2034 MOFRL domain protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D Spith_0737 Glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D Spith_0032 phospholipid/glycerol acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D Spith_1835 phospholipid/glycerol acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D Spith_2000 glycosyl transferase group 1 K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D Spith_0361 glycoside hydrolase clan GH-D K07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22] C 00564 Glycerophospholipid metabolism [PATH:stq00564] D Spith_2157 Glycerol-3-phosphate dehydrogenase (NAD(P)+) K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] D Spith_0737 Glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D Spith_0032 phospholipid/glycerol acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D Spith_1835 phospholipid/glycerol acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D Spith_0847 phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41] D Spith_0615 CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] D Spith_2283 hypothetical protein K01095 pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27] D Spith_1652 CDP-alcohol phosphatidyltransferase K08744 CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41] D Spith_0750 3-dehydroquinate synthase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism [PATH:stq00600] D Spith_2085 short-chain dehydrogenase/reductase SDR K04708 KDSR; 3-dehydrosphinganine reductase [EC:1.1.1.102] D Spith_1530 glycoside hydrolase family 30 K01201 GBA; glucosylceramidase [EC:3.2.1.45] D Spith_1935 glycoside hydrolase family 2 sugar binding protein K01190 lacZ; beta-galactosidase [EC:3.2.1.23] D Spith_0361 glycoside hydrolase clan GH-D K07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22] D Spith_0246 Glycoside hydrolase, family 20, catalytic core K12373 HEXA_B; hexosaminidase [EC:3.2.1.52] C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:stq00230] D Spith_2127 NUDIX hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D Spith_1237 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Spith_0824 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Spith_1291 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D Spith_1294 Phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D Spith_1293 phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D Spith_1289 phosphoribosylformylglycinamidine synthase K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] D Spith_1292 phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D Spith_1290 phosphoribosylaminoimidazole carboxylase, catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D Spith_0470 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D Spith_1025 fumarate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D Spith_1019 MGS domain protein K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D Spith_1020 AICARFT/IMPCHase bienzyme formylation region K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D Spith_1423 Adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Spith_0891 Multifunctional protein surE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Spith_2268 Purine nucleoside phosphorylase deoD-type K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D Spith_1047 Multi-copper polyphenol oxidoreductase, laccase K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] D Spith_1026 inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D Spith_1804 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Spith_1898 Nucleoside-triphosphatase rdgB K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D Spith_1360 molybdopterin dehydrogenase FAD-binding protein K13479 ygeT; xanthine dehydrogenase FAD-binding subunit [EC:1.17.1.4] D Spith_1028 GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Spith_0218 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Spith_1464 anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D Spith_1547 metal-dependent phosphohydrolase HD sub domain-containing protein K01129 dgt; dGTPase [EC:3.1.5.1] D Spith_1976 (p)ppGpp synthetase I, SpoT/RelA K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D Spith_2259 Ppx/GppA phosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] D Spith_0094 adenylate/guanylate cyclase with TPR repeats K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Spith_1814 adenylate/guanylate cyclase K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Spith_1252 adenylate/guanylate cyclase with integral membrane sensor K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Spith_1122 adenylate/guanylate cyclase with Chase sensor K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Spith_1920 Diverse 7TM receptor transmembrane region K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1] D Spith_1715 adenylyl cyclase CyaB K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1] D Spith_1027 Adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D Spith_2294 Adenosine deaminase K01488 add; adenosine deaminase [EC:3.5.4.4] D Spith_0854 Conserved hypothetical protein CHP00282 K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16] D Spith_0903 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Spith_1993 metallophosphoesterase K03651 cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53] D Spith_1099 histidine triad (HIT) protein K19710 E2.7.7.53; ATP adenylyltransferase [EC:2.7.7.53] D Spith_1677 sulfate adenylyltransferase, large subunit K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25] D Spith_1678 phosphoadenosine phosphosulfate reductase K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4] C 00240 Pyrimidine metabolism [PATH:stq00240] D Spith_1421 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Spith_1422 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D Spith_1443 aspartate carbamoyltransferase K00608 pyrBI; aspartate carbamoyltransferase [EC:2.1.3.2] D Spith_2018 dihydroorotase, homodimeric type K01465 URA4; dihydroorotase [EC:3.5.2.3] D Spith_2111 dihydroorotate dehydrogenase family protein K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14] D Spith_2112 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulfur cluster binding domain-containing protein K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit D Spith_1841 dihydroorotate oxidase K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1] D Spith_0883 Orotate phosphoribosyltransferase K13421 UMPS; uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23] D Spith_2173 uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D Spith_1804 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Spith_0852 Septum formation protein Maf K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-] D Spith_2236 CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2] D Spith_1260 Cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D Spith_1239 TGS domain-containing protein K00876 udk; uridine kinase [EC:2.7.1.48] D Spith_0891 Multifunctional protein surE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Spith_0854 Conserved hypothetical protein CHP00282 K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16] D Spith_0910 cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5] D Spith_0774 CMP/dCMP deaminase zinc-binding protein K01489 cdd; cytidine deaminase [EC:3.5.4.5] D Spith_1464 anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D Spith_2180 Deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13] D Spith_0218 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Spith_1157 Thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D Spith_2253 Thymidylate synthase thyX K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:stq00250] D Spith_1064 L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16] D Spith_0792 aminotransferase class I and II K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D Spith_0488 fumarate lyase K01744 aspA; aspartate ammonia-lyase [EC:4.3.1.1] D Spith_2056 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Spith_0820 Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Spith_1027 Adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D Spith_1025 fumarate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D Spith_1443 aspartate carbamoyltransferase K00608 pyrBI; aspartate carbamoyltransferase [EC:2.1.3.2] D Spith_1049 ferredoxin-dependent glutamate synthase K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D Spith_1295 glutamate synthase (NADPH), homotetrameric K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D Spith_1050 glutamate synthase, NADH/NADPH, small subunit K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D Spith_0267 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spith_1421 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Spith_1422 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D Spith_0240 sugar isomerase (SIS) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Spith_0173 Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Spith_1291 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:stq00260] D Spith_0568 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Spith_0053 aspartate kinase K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] D Spith_1966 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Spith_0178 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Spith_2225 phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein K02203 thrH; phosphoserine / homoserine phosphotransferase [EC:3.1.3.3 2.7.1.39] D Spith_0054 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D Spith_2136 aromatic amino acid beta-eliminating lyase/threonine aldolase K01620 ltaE; threonine aldolase [EC:4.1.2.48] D Spith_0158 glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Spith_2034 MOFRL domain protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165] D Spith_0500 phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Spith_0137 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Spith_0389 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Spith_0138 Phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Spith_0736 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spith_0010 Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein D Spith_0730 glycine cleavage H-protein K02437 gcvH; glycine cleavage system H protein D Spith_0169 Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D Spith_0168 Tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D Spith_1921 Tryptophan synthase beta chain K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20] C 00270 Cysteine and methionine metabolism [PATH:stq00270] D Spith_0228 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Spith_0866 cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47] D Spith_0886 cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47] D Spith_0199 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Spith_1727 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D Spith_0013 S-adenosylmethionine synthase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D Spith_0889 MTA/SAH nucleosidase K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9] D Spith_1047 Multi-copper polyphenol oxidoreductase, laccase K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] D Spith_0012 Adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D Spith_0568 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Spith_0053 aspartate kinase K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] D Spith_1966 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Spith_0178 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Spith_1383 Homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] D Spith_0867 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] D Spith_1686 Cys/Met metabolism pyridoxal-phosphate-dependent protein K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] D Spith_0162 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Spith_0137 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Spith_0389 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Spith_0138 Phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] C 00280 Valine, leucine and isoleucine degradation [PATH:stq00280] D Spith_0162 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Spith_2022 Transketolase domain-containing protein K11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] D Spith_1346 Transketolase central region K11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] D Spith_0736 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spith_1664 6-phosphogluconate dehydrogenase NAD-binding protein K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:stq00290] D Spith_0111 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Spith_2135 homoaconitate hydratase family protein K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Spith_0112 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Spith_2134 aconitate hydratase domain-containing protein K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Spith_0359 isocitrate/isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D Spith_1789 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Spith_1790 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Spith_1706 acetohydroxy acid isomeroreductase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D Spith_0775 Dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D Spith_0162 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Spith_0792 aminotransferase class I and II K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D Spith_0967 2-isopropylmalate synthase/homocitrate synthase family protein K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] D Spith_2122 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00300 Lysine biosynthesis [PATH:stq00300] D Spith_0178 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Spith_0568 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Spith_0053 aspartate kinase K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] D Spith_1966 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Spith_1305 Dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D Spith_1304 Dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] D Spith_2055 Acetylornithine/succinyldiaminopimelate aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Spith_1890 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D Spith_1834 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] D Spith_0017 Orn/DAP/Arg decarboxylase 2 K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D Spith_1827 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D Spith_0919 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] C 00310 Lysine degradation [PATH:stq00310] D Spith_0736 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spith_2128 lysine 2,3-aminomutase YodO family protein K01843 kamA; lysine 2,3-aminomutase [EC:5.4.3.2] C 00220 Arginine biosynthesis [PATH:stq00220] D Spith_0607 Ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D Spith_2056 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Spith_0820 Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Spith_0267 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spith_0792 aminotransferase class I and II K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D Spith_1803 amino-acid N-acetyltransferase K14682 argAB; amino-acid N-acetyltransferase [EC:2.3.1.1] D Spith_1742 Arginine biosynthesis bifunctional protein ArgJ K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1] D Spith_2054 acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8] D Spith_2053 N-acetyl-gamma-glutamyl-phosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] D Spith_2055 Acetylornithine/succinyldiaminopimelate aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] C 00330 Arginine and proline metabolism [PATH:stq00330] D Spith_0585 arginine decarboxylase K01585 speA; arginine decarboxylase [EC:4.1.1.19] D Spith_0284 agmatinase K01480 speB; agmatinase [EC:3.5.3.11] D Spith_0283 carboxynorspermidine decarboxylase K13747 nspC; carboxynorspermidine decarboxylase [EC:4.1.1.96] D Spith_1987 pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2] D Spith_2029 Glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D Spith_2028 Gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] C 00340 Histidine metabolism [PATH:stq00340] D Spith_1366 ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17] D Spith_1365 tRNA synthetase class II (G H P and S) K02502 hisZ; ATP phosphoribosyltransferase regulatory subunit D Spith_0649 Phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19] D Spith_0119 Phosphoribosyl-ATP pyrophosphatase K11755 hisIE; phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31] D Spith_0118 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D Spith_1642 Imidazole glycerol phosphate synthase subunit hisH K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10] D Spith_1641 Imidazole glycerol phosphate synthase subunit hisF K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10] D Spith_1367 Imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19] D Spith_1478 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Spith_1757 histidinol phosphate phosphatase HisJ family K04486 E3.1.3.15B; histidinol-phosphatase (PHP family) [EC:3.1.3.15] D Spith_0325 Histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23] C 00350 Tyrosine metabolism D Spith_1478 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00360 Phenylalanine metabolism [PATH:stq00360] D Spith_1478 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Spith_0869 Catalase-peroxidase K03782 katG; catalase-peroxidase [EC:1.11.1.21] D Spith_0593 Rieske (2Fe-2S) iron-sulfur domain-containing protein K05710 hcaC; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin component C 00380 Tryptophan metabolism [PATH:stq00380] D Spith_0736 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spith_0869 Catalase-peroxidase K03782 katG; catalase-peroxidase [EC:1.11.1.21] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:stq00400] D Spith_1461 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D Spith_1937 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 AROA2; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D Spith_1634 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4] D Spith_0281 3-dehydroquinate dehydratase K13832 aroDE; 3-dehydroquinate dehydratase / shikimate dehydrogenase [EC:4.2.1.10 1.1.1.25] D Spith_0611 Shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71] D Spith_0335 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D Spith_0610 chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D Spith_0165 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Spith_0166 Anthranilate phosphoribosyltransferase K13497 trpGD; anthranilate synthase/phosphoribosyltransferase [EC:4.1.3.27 2.4.2.18] D Spith_0167 Indole-3-glycerol phosphate synthase K13498 trpCF; indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase [EC:4.1.1.48 5.3.1.24] D Spith_0169 Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D Spith_0168 Tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D Spith_1921 Tryptophan synthase beta chain K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D Spith_1478 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism [PATH:stq00410] D Spith_0198 Aspartate 1-decarboxylase K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11] D Spith_0200 protein of unknown function DUF137 K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] C 00430 Taurine and hypotaurine metabolism [PATH:stq00430] D Spith_1303 phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D Spith_1871 Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:stq00450] D Spith_0199 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Spith_1727 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D Spith_0594 cysteine desulfurase, SufS subfamily K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D Spith_1406 thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D Spith_1677 sulfate adenylyltransferase, large subunit K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25] D Spith_1678 phosphoadenosine phosphosulfate reductase K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4] D Spith_0311 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism [PATH:stq00460] D Spith_1531 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_0366 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_0766 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_0770 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_1795 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_2148 beta-galactosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] D Spith_0158 glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism [PATH:stq00470] D Spith_0608 Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D Spith_0613 D-alanine--D-alanine ligase domain protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Spith_1828 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Spith_1776 Glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D Spith_0314 UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D Spith_0017 Orn/DAP/Arg decarboxylase 2 K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] C 00480 Glutathione metabolism [PATH:stq00480] D Spith_0022 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Spith_1886 isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D Spith_0379 6-phosphogluconate dehydrogenase, decarboxylating K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] D Spith_2050 glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis [PATH:stq00515] D Spith_1836 glycosyl transferase family 39 K00728 POMT; dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109] C 00514 Other types of O-glycan biosynthesis [PATH:stq00514] D Spith_1836 glycosyl transferase family 39 K00728 POMT; dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109] C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation [PATH:stq00511] D Spith_1935 glycoside hydrolase family 2 sugar binding protein K01190 lacZ; beta-galactosidase [EC:3.2.1.23] D Spith_0246 Glycoside hydrolase, family 20, catalytic core K12373 HEXA_B; hexosaminidase [EC:3.2.1.52] D Spith_0233 glycoside hydrolase family 2 sugar binding protein K01192 E3.2.1.25; beta-mannosidase [EC:3.2.1.25] D Spith_0382 alpha-L-fucosidase 2 precursor K15923 AXY8; alpha-L-fucosidase 2 [EC:3.2.1.51] D Spith_1530 glycoside hydrolase family 30 K01201 GBA; glucosylceramidase [EC:3.2.1.45] C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:stq00541] D Spith_0089 Nucleotidyl transferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Spith_0358 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Spith_1626 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Spith_0011 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Spith_0050 NAD-dependent epimerase/dehydratase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6] D Spith_1819 mannose-6-phosphate isomerase, class I K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D Spith_0163 Nucleotidyl transferase K16011 algA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8] D Spith_1623 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47] D Spith_1622 NAD-dependent epimerase/dehydratase K02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271] D Spith_0632 oxidoreductase domain protein K13020 wlbA; UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase [EC:1.1.1.335] C 00550 Peptidoglycan biosynthesis [PATH:stq00550] D Spith_0051 UDP-N-acetylglucosamine1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D Spith_1868 UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D Spith_1262 UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D Spith_0314 UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D Spith_1827 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D Spith_0613 D-alanine--D-alanine ligase domain protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Spith_1828 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Spith_0919 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D Spith_0848 Undecaprenyl pyrophosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D Spith_1858 Undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D Spith_0920 Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D Spith_0562 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D Spith_1441 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Spith_0073 penicillin-binding protein 1C K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28] D Spith_1116 penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D Spith_1419 penicillin-binding protein transpeptidase K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D Spith_1851 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D Spith_1700 peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] C 00552 Teichoic acid biosynthesis [PATH:stq00552] D Spith_1858 Undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D Spith_0041 glycosyl transferase, WecB/TagA/CpsF family K05946 tagA; N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase [EC:2.4.1.187] D Spith_1057 membrane-bound protein LytR K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-] D Spith_2000 glycosyl transferase group 1 K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D Spith_1606 LicD family protein K07271 licD; lipopolysaccharide cholinephosphotransferase [EC:2.7.8.-] C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis [PATH:stq00543] D Spith_0228 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:stq00730] D Spith_0131 Phosphomethylpyrimidine synthase K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17] D Spith_0133 UBA/THIF-type NAD/FAD binding protein K03148 thiF; sulfur carrier protein ThiS adenylyltransferase [EC:2.7.7.73] D Spith_1638 aminotransferase class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Spith_1639 tRNA sulfurtransferase K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D Spith_0134 thiazole biosynthesis protein ThiH K03150 thiH; 2-iminoacetate synthase [EC:4.1.99.19] D Spith_0486 biotin and thiamin synthesis associated K03150 thiH; 2-iminoacetate synthase [EC:4.1.99.19] D Spith_1881 1-deoxy-D-xylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7] D Spith_0135 Thiazole synthase K03149 thiG; thiazole synthase [EC:2.8.1.10] D Spith_0132 Thiamine-phosphate pyrophosphorylase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3] D Spith_0740 ribosome biogenesis GTPase RsgA K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D Spith_1775 Sigma 54 interacting domain protein K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D Spith_1266 Alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D Spith_1098 thiamine pyrophosphokinase K00949 thiN; thiamine pyrophosphokinase [EC:2.7.6.2] D Spith_0903 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism [PATH:stq00740] D Spith_0467 GTP cyclohydrolase-2 K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D Spith_0465 riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D Spith_0468 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D Spith_0466 riboflavin synthase, alpha subunit K00793 ribE; riboflavin synthase [EC:2.5.1.9] D Spith_1144 cytidyltransferase-related domain protein K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D Spith_2127 NUDIX hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] C 00750 Vitamin B6 metabolism [PATH:stq00750] D Spith_2011 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein K00275 pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5] D Spith_0138 Phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D Spith_0054 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D Spith_1783 Pyridoxal biosynthesis lyase pdxS K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6] D Spith_1784 Glutamine amidotransferase subunit pdxT K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6] C 00760 Nicotinate and nicotinamide metabolism [PATH:stq00760] D Spith_1064 L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16] D Spith_2150 quinolinate synthetase complex, A subunit K03517 nadA; quinolinate synthase [EC:2.5.1.72] D Spith_1063 nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D Spith_1452 nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21] D Spith_2268 Purine nucleoside phosphorylase deoD-type K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D Spith_0891 Multifunctional protein surE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Spith_1055 nicotinate-nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] D Spith_0021 NAD+ synthetase K01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1] D Spith_1453 isochorismatase hydrolase K08281 pncA; nicotinamidase/pyrazinamidase [EC:3.5.1.19 3.5.1.-] D Spith_0907 inorganic polyphosphate/ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] C 00770 Pantothenate and CoA biosynthesis [PATH:stq00770] D Spith_1789 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Spith_1790 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Spith_1706 acetohydroxy acid isomeroreductase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D Spith_0775 Dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D Spith_0195 3-methyl-2-oxobutanoatehydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11] D Spith_0201 GHMP kinase K06982 pok; pantoate kinase [EC:2.7.1.169] D Spith_0200 protein of unknown function DUF137 K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] D Spith_0197 DNA/pantothenate metabolism flavoprotein domain protein K21977 coaB; phosphopantothenate---cysteine ligase (CTP) [EC:6.3.2.5] D Spith_0196 flavoprotein K01598 PPCDC; phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36] D Spith_1091 Phosphopantetheine adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D Spith_0226 Dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24] D Spith_1877 Holo-(acyl-carrier-protein) synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7] D Spith_0162 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Spith_0198 Aspartate 1-decarboxylase K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11] C 00780 Biotin metabolism [PATH:stq00780] D Spith_0828 Methyltransferase type 11 K02169 bioC; malonyl-CoA O-methyltransferase [EC:2.1.1.197] D Spith_2196 3-oxoacyl-(acyl-carrier-protein) synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D Spith_0387 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spith_1224 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spith_2197 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spith_1749 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spith_1317 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D Spith_0829 protein of unknown function DUF452 K09789 bioG; pimeloyl-[acyl-carrier protein] methyl ester esterase [EC:3.1.1.85] D Spith_0830 aminotransferase class I and II K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D Spith_2086 aminotransferase class I and II K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D Spith_0831 aminotransferase class-III K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62] D Spith_0827 Dethiobiotin synthetase K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3] D Spith_0487 Radical SAM domain protein K01012 bioB; biotin synthase [EC:2.8.1.6] D Spith_1256 Biotin synthase K01012 bioB; biotin synthase [EC:2.8.1.6] D Spith_0785 biotin/acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D Spith_2049 biotin/acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism [PATH:stq00785] D Spith_0418 Octanoyltransferase K03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181] D Spith_0294 Lipoyl synthase K03644 lipA; lipoyl synthase [EC:2.8.1.8] D Spith_2269 biotin/lipoate A/B protein ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D Spith_0736 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spith_2010 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D Spith_2009 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D Spith_2008 catalytic domain-containing protein of components of various dehydrogenase complexes K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Spith_1347 catalytic domain-containing protein of components of various dehydrogenase complexes K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D Spith_2022 Transketolase domain-containing protein K11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] D Spith_1346 Transketolase central region K11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] D Spith_0010 Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein D Spith_0730 glycine cleavage H-protein K02437 gcvH; glycine cleavage system H protein C 00790 Folate biosynthesis [PATH:stq00790] D Spith_1018 protein of unknown function DUF198 K09007 folE2; GTP cyclohydrolase IB [EC:3.5.4.16] D Spith_1266 Alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D Spith_1129 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D Spith_1880 dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15] D Spith_0324 FolC bifunctional protein K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D Spith_0467 GTP cyclohydrolase-2 K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D Spith_1826 6-pyruvoyl tetrahydropterin synthase and hypothetical protein K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D Spith_0708 hypothetical protein K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105] C 00670 One carbon pool by folate [PATH:stq00670] D Spith_1017 Bifunctional protein folD K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D Spith_0158 glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Spith_1293 phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D Spith_1019 MGS domain protein K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D Spith_1020 AICARFT/IMPCHase bienzyme formylation region K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D Spith_2079 Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D Spith_0199 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D Spith_2253 Thymidylate synthase thyX K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148] D Spith_1716 formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10] D Spith_2204 5,10-methylenetetrahydrofolate reductase K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54] D Spith_0208 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:stq00860] D Spith_0793 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Spith_1675 Glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70] D Spith_1672 Glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D Spith_1673 delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D Spith_1674 uroporphyrin-III C-methyltransferase K13542 cobA-hemD; uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75] D Spith_1676 hypothetical protein K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76] D Spith_1038 ATP/cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D Spith_1491 ATPase associated with various cellular activities AAA_5 K03405 chlI; magnesium chelatase subunit I [EC:6.6.1.1] D Spith_2232 Ferritin Dps family protein K03594 bfr; bacterioferritin [EC:1.16.3.1] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:stq00130] D Spith_2031 UbiA prenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74] D Spith_0617 flavodoxin/nitric oxide synthase K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] D Spith_1225 flavoprotein WrbA K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] D Spith_1850 hypothetical protein K19267 qorB; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:stq00900] D Spith_1881 1-deoxy-D-xylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7] D Spith_0846 1-deoxy-D-xylulose 5-phosphate reductoisomerase K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267] D Spith_1944 4-diphosphocytidyl-2C-methyl-D-erythritolsynthas e K00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60] D Spith_1065 4-diphosphocytidyl-2-C-methyl-D-erythritolkinase K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148] D Spith_1945 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase K01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12] D Spith_1244 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3] D Spith_1785 hydroxymethylbutenyl pyrophosphate reductase K03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] D Spith_1786 Polyprenyl synthetase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D Spith_0848 Undecaprenyl pyrophosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D Spith_0122 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids [PATH:stq00946] D Spith_1531 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_0366 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_0766 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_0770 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_1795 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_2148 beta-galactosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] D Spith_1326 alpha-L-rhamnosidase K05989 ramA; alpha-L-rhamnosidase [EC:3.2.1.40] C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis D Spith_0436 Acetyl xylan esterase K01060 cah; cephalosporin-C deacetylase [EC:3.1.1.41] C 00332 Carbapenem biosynthesis [PATH:stq00332] D Spith_2029 Glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D Spith_2028 Gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] C 00261 Monobactam biosynthesis [PATH:stq00261] D Spith_1677 sulfate adenylyltransferase, large subunit K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25] D Spith_1678 phosphoadenosine phosphosulfate reductase K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4] D Spith_0568 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Spith_0053 aspartate kinase K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] D Spith_1966 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Spith_1305 Dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D Spith_1304 Dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:stq00521] D Spith_0651 Glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D Spith_1237 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D Spith_0671 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] C 00524 Neomycin, kanamycin and gentamicin biosynthesis D Spith_0651 Glucokinase K00845 glk; glucokinase [EC:2.7.1.2] C 00525 Acarbose and validamycin biosynthesis C 00401 Novobiocin biosynthesis D Spith_1478 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D Spith_0165 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis D Spith_2198 malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D Spith_0387 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spith_1224 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spith_2197 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spith_1749 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics D Spith_1094 Acyl carrier protein K02078 acpP; acyl carrier protein C 00999 Biosynthesis of various plant secondary metabolites [PATH:stq00999] D Spith_0013 S-adenosylmethionine synthase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D Spith_0281 3-dehydroquinate dehydratase K13832 aroDE; 3-dehydroquinate dehydratase / shikimate dehydrogenase [EC:4.2.1.10 1.1.1.25] D Spith_1531 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_0366 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_0766 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_0770 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_1795 glycoside hydrolase family 3 domain protein K05349 bglX; beta-glucosidase [EC:3.2.1.21] D Spith_2148 beta-galactosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation D Spith_2201 sodium ion-translocating decarboxylase, beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] C 00627 Aminobenzoate degradation D Spith_2059 Acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation D Spith_2179 HAD superfamily (subfamily IA) hydrolase, TIGR02254 K01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2] C 00361 Chlorocyclohexane and chlorobenzene degradation D Spith_2179 HAD superfamily (subfamily IA) hydrolase, TIGR02254 K01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2] C 00623 Toluene degradation C 00622 Xylene degradation C 00633 Nitrotoluene degradation C 00642 Ethylbenzene degradation C 00643 Styrene degradation C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation C 00626 Naphthalene degradation C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:stq03020] D Spith_0512 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D Spith_0513 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D Spith_0543 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D Spith_1259 DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] C 03022 Basal transcription factors D Spith_0293 type III restriction protein res subunit K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:stq03010] D Spith_1125 Cytidylate kinase K02945 RP-S1; small subunit ribosomal protein S1 D Spith_0851 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D Spith_0524 ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D Spith_0542 ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D Spith_0535 ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D Spith_0838 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D Spith_0515 ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D Spith_0532 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D Spith_2161 ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D Spith_0517 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D Spith_0541 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D Spith_0514 ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D Spith_0540 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D Spith_0531 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D Spith_1143 ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D Spith_1079 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D Spith_0527 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D Spith_0840 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D Spith_0522 ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D Spith_1902 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D Spith_0670 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D Spith_0509 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D Spith_0521 ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D Spith_0518 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D Spith_0519 ribosomal protein L4/L1e K02926 RP-L4; large subunit ribosomal protein L4 D Spith_0530 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Spith_0533 ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D Spith_0511 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D Spith_0842 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D Spith_0510 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D Spith_0508 ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Spith_2162 ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D Spith_0528 ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D Spith_0537 ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D Spith_0525 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D Spith_0544 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D Spith_0534 ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D Spith_1083 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D Spith_1387 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D Spith_1051 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D Spith_0523 ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D Spith_0520 Ribosomal protein L25/L23 K02892 RP-L23; large subunit ribosomal protein L23 D Spith_0529 ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D Spith_1067 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25 D Spith_1053 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D Spith_0219 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D Spith_0526 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Spith_0536 ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D Spith_2038 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D Spith_1093 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D Spith_0505 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D Spith_0005 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D Spith_1386 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D Spith_0539 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 D Spith_R0008 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Spith_R0033 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Spith_R0010 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Spith_R0031 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Spith_R0011 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Spith_R0030 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:stq00970] D Spith_R0009 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Spith_R0017 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Spith_R0048 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Spith_R0044 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spith_R0001 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spith_R0002 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spith_R0015 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spith_R0053 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spith_R0027 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Spith_R0025 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Spith_R0043 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Spith_R0035 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Spith_R0021 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Spith_R0034 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Spith_R0019 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Spith_R0041 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Spith_R0012 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Spith_R0026 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Spith_R0016 tRNA-His K14226 tRNA-His; tRNA His D Spith_R0032 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Spith_R0047 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spith_R0004 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spith_R0013 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spith_R0049 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spith_R0029 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spith_R0014 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Spith_R0018 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Spith_R0037 tRNA-Met K14230 tRNA-Met; tRNA Met D Spith_R0038 tRNA-Met K14230 tRNA-Met; tRNA Met D Spith_R0005 tRNA-Met K14230 tRNA-Met; tRNA Met D Spith_R0028 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Spith_R0003 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Spith_R0024 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Spith_R0045 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Spith_R0051 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spith_R0052 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spith_R0054 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spith_R0055 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spith_R0040 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Spith_R0006 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Spith_R0036 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Spith_R0007 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Spith_R0039 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Spith_R0042 tRNA-Val K14237 tRNA-Val; tRNA Val D Spith_R0046 tRNA-Val K14237 tRNA-Val; tRNA Val D Spith_R0020 tRNA-Val K14237 tRNA-Val; tRNA Val D Spith_0793 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Spith_2265 Glutamyl-tRNA(Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D Spith_2264 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Spith_2266 glutamyl-tRNA(Gln) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D Spith_1543 Glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18] D Spith_1371 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Spith_0145 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Spith_2263 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D Spith_0498 Asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D Spith_0794 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Spith_1663 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Spith_1988 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Spith_1867 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Spith_0311 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Spith_2079 Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D Spith_0441 Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Spith_0352 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Spith_1644 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Spith_0419 Lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Spith_1048 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Spith_0025 Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Spith_0257 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Spith_1632 Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Spith_2221 Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Spith_2222 Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Spith_0795 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Spith_0805 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:stq03060] D Spith_0538 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Spith_0506 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Spith_1007 preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Spith_1997 protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD D Spith_1996 protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF D Spith_1998 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Spith_0008 Membrane protein oxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase D Spith_1416 Protein translocase subunit secA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Spith_1078 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Spith_R0050 RNA component of signal recognition particle K01983 ffs; SRP RNA D Spith_1283 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Spith_0654 Anion-transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Spith_1165 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D Spith_1166 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D Spith_2186 Lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:stq04122] D Spith_1638 aminotransferase class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Spith_2093 tRNA-specific 2-thiouridylase mnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D Spith_1685 UBA/THIF-type NAD/FAD binding protein K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80] D Spith_1639 tRNA sulfurtransferase K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D Spith_0136 thiamine biosynthesis protein ThiS K03154 thiS; sulfur carrier protein D Spith_1687 thiamine biosynthesis protein ThiS K03154 thiS; sulfur carrier protein D Spith_0133 UBA/THIF-type NAD/FAD binding protein K03148 thiF; sulfur carrier protein ThiS adenylyltransferase [EC:2.7.7.73] D Spith_1682 Mov34/MPN/PAD-1 family protein K21140 mec; [CysO sulfur-carrier protein]-S-L-cysteine hydrolase [EC:3.13.1.6] C 03050 Proteasome C 03018 RNA degradation [PATH:stq03018] D Spith_2058 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Spith_1142 Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D Spith_1728 DbpA RNA-binding domain protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Spith_2039 transcription termination factor Rho K03628 rho; transcription termination factor Rho D Spith_0853 2,3 cyclic-nucleotide 2-phosphodiesterase K18682 rny; ribonucrease Y [EC:3.1.-.-] D Spith_0248 phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spith_1913 Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK D Spith_2047 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Spith_2258 polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] D Spith_0055 metal dependent phosphohydrolase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] D Spith_1631 poly(A) polymerase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] B B 09124 Replication and repair C 03030 DNA replication [PATH:stq03030] D Spith_1235 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Spith_1361 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Spith_2280 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Spith_0564 DNA polymerase III domain-containing protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Spith_2248 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Spith_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Spith_0843 replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D Spith_1109 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D Spith_0839 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Spith_0547 Ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D Spith_1075 ribonuclease HII/HIII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Spith_0225 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Spith_1354 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03410 Base excision repair [PATH:stq03410] D Spith_2110 HhH-GPD family protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D Spith_0807 HhH-GPD family protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D Spith_1874 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D Spith_1972 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D Spith_0225 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Spith_0668 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Spith_1354 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03420 Nucleotide excision repair [PATH:stq03420] D Spith_1198 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D Spith_1241 UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A D Spith_0550 UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B D Spith_2249 UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C D Spith_2167 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Spith_1375 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Spith_0225 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Spith_1354 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Spith_0293 type III restriction protein res subunit K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] C 03430 Mismatch repair [PATH:stq03430] D Spith_1153 DNA mismatch repair protein mutS K03555 mutS; DNA mismatch repair protein MutS D Spith_1772 MutS2 protein K07456 mutS2; DNA mismatch repair protein MutS2 D Spith_0678 DNA mismatch repair protein mutL K03572 mutL; DNA mismatch repair protein MutL D Spith_2167 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Spith_1375 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Spith_0984 Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D Spith_0983 Exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D Spith_0668 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Spith_0839 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Spith_1361 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Spith_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Spith_2280 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Spith_2248 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Spith_0564 DNA polymerase III domain-containing protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Spith_1235 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Spith_1354 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03440 Homologous recombination [PATH:stq03440] D Spith_0668 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Spith_0839 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Spith_0003 DNA replication and repair protein recF K03629 recF; DNA replication and repair protein RecF D Spith_1698 DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O) D Spith_2278 Recombination protein recR K06187 recR; recombination protein RecR D Spith_1130 Protein recA K03553 recA; recombination protein RecA D Spith_0225 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Spith_1161 Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA D Spith_1160 Holliday junction ATP-dependent DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D Spith_1162 Crossover junction endodeoxyribonuclease ruvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D Spith_1363 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D Spith_1361 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Spith_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Spith_2280 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Spith_2248 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Spith_0564 DNA polymerase III domain-containing protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Spith_1235 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Spith_1873 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] C 03450 Non-homologous end-joining C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus and Lyssavirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:stq02010] D Spith_0493 ABC-type glycine betaine transport, periplasmic subunit K05845 opuC; osmoprotectant transport system substrate-binding protein D Spith_0490 ABC-type transporter, integral membrane subunit K05846 opuBD; osmoprotectant transport system permease protein D Spith_0492 ABC-type transporter, integral membrane subunit K05846 opuBD; osmoprotectant transport system permease protein D Spith_0491 ABC transporter related protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] D Spith_1228 ABC transporter related protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D Spith_0182 ABC transporter related protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D Spith_1041 extracellular solute-binding protein family 1 K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein D Spith_1042 ABC-type transporter, integral membrane subunit K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D Spith_1043 ABC-type transporter, integral membrane subunit K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D Spith_2103 extracellular solute-binding protein family 1 K10117 msmE; raffinose/stachyose/melibiose transport system substrate-binding protein D Spith_0243 extracellular solute-binding protein family 1 K10117 msmE; raffinose/stachyose/melibiose transport system substrate-binding protein D Spith_0244 ABC-type transporter, integral membrane subunit K10118 msmF; raffinose/stachyose/melibiose transport system permease protein D Spith_2102 ABC-type transporter, integral membrane subunit K10118 msmF; raffinose/stachyose/melibiose transport system permease protein D Spith_1328 ABC-type transporter, integral membrane subunit K10118 msmF; raffinose/stachyose/melibiose transport system permease protein D Spith_2101 ABC-type transporter, integral membrane subunit K10119 msmG; raffinose/stachyose/melibiose transport system permease protein D Spith_1327 ABC-type transporter, integral membrane subunit K10119 msmG; raffinose/stachyose/melibiose transport system permease protein D Spith_0245 ABC-type transporter, integral membrane subunit K10119 msmG; raffinose/stachyose/melibiose transport system permease protein D Spith_0717 extracellular solute-binding protein family 1 K10232 aglE; alpha-glucoside transport system substrate-binding protein D Spith_0718 ABC-type transporter, integral membrane subunit K10233 aglF; alpha-glucoside transport system permease protein D Spith_0719 ABC-type transporter, integral membrane subunit K10234 aglG; alpha-glucoside transport system permease protein D Spith_0355 extracellular solute-binding protein family 1 K17318 lplA; putative aldouronate transport system substrate-binding protein D Spith_0396 extracellular solute-binding protein family 1 K17318 lplA; putative aldouronate transport system substrate-binding protein D Spith_1932 sugar ABC transporter substrate-binding protein K17318 lplA; putative aldouronate transport system substrate-binding protein D Spith_0370 extracellular solute-binding protein family 1 K17318 lplA; putative aldouronate transport system substrate-binding protein D Spith_1323 extracellular solute-binding protein family 1 K17318 lplA; putative aldouronate transport system substrate-binding protein D Spith_0368 ABC-type transporter, integral membrane subunit K17319 lplB; putative aldouronate transport system permease protein D Spith_0353 ABC-type transporter, integral membrane subunit K17319 lplB; putative aldouronate transport system permease protein D Spith_0393 ABC-type transporter, integral membrane subunit K17319 lplB; putative aldouronate transport system permease protein D Spith_1325 ABC-type transporter, integral membrane subunit K17319 lplB; putative aldouronate transport system permease protein D Spith_1934 ABC-type transporter, integral membrane subunit K17319 lplB; putative aldouronate transport system permease protein D Spith_0354 ABC-type transporter, integral membrane subunit K17320 lplC; putative aldouronate transport system permease protein D Spith_0369 ABC-type transporter, integral membrane subunit K17320 lplC; putative aldouronate transport system permease protein D Spith_1933 ABC-type transporter, integral membrane subunit K17320 lplC; putative aldouronate transport system permease protein D Spith_1324 ABC-type transporter, integral membrane subunit K17320 lplC; putative aldouronate transport system permease protein D Spith_1896 extracellular solute-binding protein family 1 K10240 cebE; cellobiose transport system substrate-binding protein D Spith_1895 ABC-type transporter, integral membrane subunit K10241 cebF; cellobiose transport system permease protein D Spith_1894 ABC-type transporter, integral membrane subunit K10242 cebG; cellobiose transport system permease protein D Spith_1435 Mammalian cell entry related domain protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein D Spith_1433 protein of unknown function DUF140 K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein D Spith_1434 ABC transporter related protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein D Spith_1845 basic membrane lipoprotein K07335 bmpA; basic membrane protein A and related proteins D Spith_1958 basic membrane lipoprotein K07335 bmpA; basic membrane protein A and related proteins D Spith_1843 ABC-type transporter, integral membrane subunit K23535 nupB; general nucleoside transport system permease protein D Spith_1956 ABC-type transporter, integral membrane subunit K23535 nupB; general nucleoside transport system permease protein D Spith_1955 ABC-type transporter, integral membrane subunit K23536 nupC; general nucleoside transport system permease protein D Spith_1842 ABC-type transporter, integral membrane subunit K23536 nupC; general nucleoside transport system permease protein D Spith_1844 ABC transporter related protein K23537 nupA; general nucleoside transport system ATP-binding protein D Spith_1957 ABC transporter related protein K23537 nupA; general nucleoside transport system ATP-binding protein D Spith_1449 extracellular solute-binding protein family 1 K17315 gtsA; glucose/mannose transport system substrate-binding protein D Spith_1450 ABC-type transporter, integral membrane subunit K17316 gtsB; glucose/mannose transport system permease protein D Spith_1451 ABC-type transporter, integral membrane subunit K17317 gtsC; glucose/mannose transport system permease protein D Spith_0425 periplasmic binding protein/LacI transcriptional regulator K10439 rbsB; ribose transport system substrate-binding protein D Spith_2099 periplasmic binding protein/LacI transcriptional regulator K10439 rbsB; ribose transport system substrate-binding protein D Spith_0424 ABC-type transporter, integral membrane subunit K10440 rbsC; ribose transport system permease protein D Spith_2098 ABC-type transporter, integral membrane subunit K10440 rbsC; ribose transport system permease protein D Spith_2097 ABC transporter related protein K10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7] D Spith_0423 ABC transporter related protein K10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7] D Spith_0407 D-ribose pyranase K06726 rbsD; D-ribose pyranase [EC:5.4.99.62] D Spith_0307 transporter K10543 xylF; D-xylose transport system substrate-binding protein D Spith_0309 ABC-type transporter, integral membrane subunit K10544 xylH; D-xylose transport system permease protein D Spith_0308 ABC transporter related protein K10545 xylG; D-xylose transport system ATP-binding protein [EC:7.5.2.10] D Spith_1339 rhamnose ABC transporter, periplasmic rhamnose-binding protein K10559 rhaS; rhamnose transport system substrate-binding protein D Spith_1337 ABC-type transporter, integral membrane subunit K10560 rhaP; rhamnose transport system permease protein D Spith_1336 ABC-type transporter, integral membrane subunit K10561 rhaQ; rhamnose transport system permease protein D Spith_1338 ABC transporter related protein K10562 rhaT; rhamnose transport system ATP-binding protein [EC:7.5.2.-] D Spith_0552 phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein D Spith_0553 phosphate ABC transporter, inner membrane subunit PstC K02037 pstC; phosphate transport system permease protein D Spith_0554 phosphate ABC transporter, inner membrane subunit PstA K02038 pstA; phosphate transport system permease protein D Spith_0555 phosphate ABC transporter, ATPase subunit K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Spith_0120 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein D Spith_1953 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein D Spith_1952 ABC-type transporter, integral membrane subunit K01997 livH; branched-chain amino acid transport system permease protein D Spith_1951 ABC-type transporter, integral membrane subunit K01998 livM; branched-chain amino acid transport system permease protein D Spith_1950 ABC transporter related protein K01995 livG; branched-chain amino acid transport system ATP-binding protein D Spith_1949 ABC transporter related protein K01996 livF; branched-chain amino acid transport system ATP-binding protein D Spith_0260 ABC-type transporter, periplasmic subunit K15580 oppA; oligopeptide transport system substrate-binding protein D Spith_0261 ABC-type transporter, integral membrane subunit K15581 oppB; oligopeptide transport system permease protein D Spith_0262 ABC-type transporter, integral membrane subunit K15582 oppC; oligopeptide transport system permease protein D Spith_0263 oligopeptide/dipeptide ABC transporter, ATPase subunit K15583 oppD; oligopeptide transport system ATP-binding protein D Spith_0264 oligopeptide/dipeptide ABC transporter, ATPase subunit K10823 oppF; oligopeptide transport system ATP-binding protein D Spith_0634 ABC-type metal ion transporter, periplasmic subunit K09815 znuA; zinc transport system substrate-binding protein D Spith_0636 ABC-type transporter, integral membrane subunit K09816 znuB; zinc transport system permease protein D Spith_0635 ABC transporter related protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D Spith_1480 cobalamin (vitamin B12) biosynthesis CbiM protein K02007 cbiM; cobalt/nickel transport system permease protein D Spith_0784 BioY protein K03523 bioY; biotin transport system substrate-specific component D Spith_0782 ABC-type transporter, integral membrane subunit K16783 bioN; biotin transport system permease protein D Spith_0783 ABC transporter related protein K16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-] D Spith_2076 ABC-2 type transporter K09694 nodJ; lipooligosaccharide transport system permease protein D Spith_2075 ABC transporter related protein K09695 nodI; lipooligosaccharide transport system ATP-binding protein D Spith_1279 protein of unknown function DUF214 K09808 lolC_E; lipoprotein-releasing system permease protein D Spith_1281 protein of unknown function DUF214 K09808 lolC_E; lipoprotein-releasing system permease protein D Spith_2284 protein of unknown function DUF214 K09808 lolC_E; lipoprotein-releasing system permease protein D Spith_1280 ABC transporter related protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] D Spith_1141 permease YjgP/YjgQ family protein K07091 lptF; lipopolysaccharide export system permease protein D Spith_1140 permease YjgP/YjgQ family protein K11720 lptG; lipopolysaccharide export system permease protein D Spith_2239 ABC transporter related protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5] D Spith_0620 ABC transporter related protein K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump D Spith_0619 ABC transporter related protein K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump C 02060 Phosphotransferase system (PTS) [PATH:stq02060] D Spith_0857 phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D Spith_2243 Phosphotransferase system, phosphocarrier protein HPr K02784 ptsH; phosphocarrier protein HPr D Spith_2035 PTS system Galactitol-specific IIC component K02775 gatC; galactitol PTS system EIIC component D Spith_0341 putative PTS IIA-like nitrogen-regulatory protein PtsN K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-] D Spith_2281 putative PTS IIA-like nitrogen-regulatory protein PtsN K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-] C 03070 Bacterial secretion system [PATH:stq03070] D Spith_1982 hypothetical protein K12340 tolC; outer membrane protein D Spith_1580 type II and III secretion system protein K02453 gspD; general secretion pathway protein D D Spith_1577 general secretion pathway protein G K02456 gspG; general secretion pathway protein G D Spith_1579 type II secretion system protein E K02454 gspE; general secretion pathway protein E [EC:7.4.2.8] D Spith_1997 protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD D Spith_1996 protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF D Spith_0506 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Spith_1007 preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Spith_0538 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Spith_1998 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Spith_0008 Membrane protein oxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase D Spith_1416 Protein translocase subunit secA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Spith_1283 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Spith_1078 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] B B 09132 Signal transduction C 02020 Two-component system [PATH:stq02020] D Spith_0558 multi-sensor signal transduction histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D Spith_1266 Alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D Spith_0552 phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein D Spith_2156 peptidase S1 and S6 chymotrypsin/Hap K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_1808 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_1014 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_1072 PDZ/DHR/GLGF domain protein K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_1097 flagellin domain protein K02406 fliC; flagellin D Spith_1392 flagellin domain protein K02406 fliC; flagellin D Spith_1393 flagellin domain protein K02406 fliC; flagellin D Spith_0959 RNA polymerase, sigma 28 subunit, FliA/WhiG K02405 fliA; RNA polymerase sigma factor FliA D Spith_0945 MotA/TolQ/ExbB proton channel K02556 motA; chemotaxis protein MotA D Spith_0631 protein of unknown function DUF112 transmembrane K07793 tctA; putative tricarboxylic transport membrane protein D Spith_0630 hypothetical protein K07794 tctB; putative tricarboxylic transport membrane protein D Spith_0629 tricarboxylic transport K07795 tctC; putative tricarboxylic transport membrane protein D Spith_0001 Chromosomal replication initiator protein dnaA K02313 dnaA; chromosomal replication initiator protein D Spith_1700 peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D Spith_1401 carbon storage regulator, CsrA K03563 csrA; carbon storage regulator D Spith_0267 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spith_2245 integral membrane sensor signal transduction histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] D Spith_2246 two component, sigma54 specific, transcriptional regulator, Fis family K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX D Spith_0836 transcriptional regulator, NifA, Fis Family K02584 nifA; Nif-specific regulatory protein D Spith_1124 transcriptional regulator, NifA subfamily, Fis Family K02584 nifA; Nif-specific regulatory protein D Spith_0042 Sigma 54 interacting domain protein K07713 zraR; two-component system, NtrC family, response regulator HydG D Spith_0305 PAS/PAC sensor signal transduction histidine kinase K07710 atoS; two-component system, NtrC family, sensor histidine kinase AtoS [EC:2.7.13.3] D Spith_0306 two component, sigma54 specific, transcriptional regulator, Fis family K07714 atoC; two-component system, NtrC family, response regulator AtoC D Spith_2240 RNA polymerase, sigma 54 subunit, RpoN K03092 rpoN; RNA polymerase sigma-54 factor D Spith_0108 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Spith_2235 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Spith_0087 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_0093 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_0100 methyl-accepting chemotaxis sensory transducer with Cache sensor K03406 mcp; methyl-accepting chemotaxis protein D Spith_0101 methyl-accepting chemotaxis sensory transducer with Cache sensor K03406 mcp; methyl-accepting chemotaxis protein D Spith_0107 hypothetical protein K03406 mcp; methyl-accepting chemotaxis protein D Spith_0231 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_0185 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_0204 methyl-accepting chemotaxis sensory transducer with Cache sensor K03406 mcp; methyl-accepting chemotaxis protein D Spith_0375 methyl-accepting chemotaxis sensory transducer with Cache sensor K03406 mcp; methyl-accepting chemotaxis protein D Spith_1194 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_1332 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_1582 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_1659 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_2125 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_2140 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_2145 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_0106 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW D Spith_0905 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW D Spith_1793 MCP methyltransferase, CheR-type K03408 cheW; purine-binding chemotaxis protein CheW D Spith_0104 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spith_1794 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spith_0105 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_0817 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_0330 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_1190 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_1791 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_0110 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spith_2234 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spith_0384 TRAP dicarboxylate transporter, DctP subunit K11688 dctP; C4-dicarboxylate-binding protein DctP D Spith_0385 Tripartite ATP-independent periplasmic transporter DctQ component K11689 dctQ; C4-dicarboxylate transporter, DctQ subunit D Spith_0172 putative transcriptional regulator, Crp/Fnr family K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spith_1430 putative transcriptional regulator, Crp/Fnr family K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spith_1331 integral membrane sensor signal transduction histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D Spith_2141 transcriptional regulator, AraC family K07720 yesN; two-component system, response regulator YesN D Spith_1330 two component transcriptional regulator, AraC family K07720 yesN; two-component system, response regulator YesN D Spith_1340 two component transcriptional regulator, AraC family K07720 yesN; two-component system, response regulator YesN D Spith_1982 hypothetical protein K12340 tolC; outer membrane protein D Spith_1636 Soluble ligand binding domain-containing protein K01991 wza; polysaccharide biosynthesis/export protein D Spith_0779 glycoside hydrolase family 5 K01179 E3.2.1.4; endoglucanase [EC:3.2.1.4] D Spith_2109 glycoside hydrolase family 5 K01179 E3.2.1.4; endoglucanase [EC:3.2.1.4] D Spith_2107 glycoside hydrolase family 9 K01179 E3.2.1.4; endoglucanase [EC:3.2.1.4] D Spith_1446 glycoside hydrolase family 5 K01179 E3.2.1.4; endoglucanase [EC:3.2.1.4] D Spith_1704 glycoside hydrolase family 9 K01179 E3.2.1.4; endoglucanase [EC:3.2.1.4] D Spith_2108 glycoside hydrolase family 9 K01179 E3.2.1.4; endoglucanase [EC:3.2.1.4] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:stq02024] D Spith_0165 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Spith_1461 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D Spith_0864 Antibiotic biosynthesis monooxygenase K11530 lsrG; (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase [EC:5.3.1.32] D Spith_0120 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein D Spith_1953 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein D Spith_1952 ABC-type transporter, integral membrane subunit K01997 livH; branched-chain amino acid transport system permease protein D Spith_1951 ABC-type transporter, integral membrane subunit K01998 livM; branched-chain amino acid transport system permease protein D Spith_1950 ABC transporter related protein K01995 livG; branched-chain amino acid transport system ATP-binding protein D Spith_1949 ABC transporter related protein K01996 livF; branched-chain amino acid transport system ATP-binding protein D Spith_0083 hemagluttinin repeat-containing protein K20276 bapA; large repetitive protein D Spith_0140 hypothetical protein K20276 bapA; large repetitive protein D Spith_0285 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spith_1318 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spith_1549 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spith_0172 putative transcriptional regulator, Crp/Fnr family K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spith_1430 putative transcriptional regulator, Crp/Fnr family K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spith_1286 glycoside hydrolase family 5 K01218 gmuG; mannan endo-1,4-beta-mannosidase [EC:3.2.1.78] D Spith_0465 riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D Spith_2212 outer membrane efflux protein K18139 oprM; outer membrane protein, multidrug efflux system D Spith_0260 ABC-type transporter, periplasmic subunit K15580 oppA; oligopeptide transport system substrate-binding protein D Spith_0261 ABC-type transporter, integral membrane subunit K15581 oppB; oligopeptide transport system permease protein D Spith_0262 ABC-type transporter, integral membrane subunit K15582 oppC; oligopeptide transport system permease protein D Spith_0263 oligopeptide/dipeptide ABC transporter, ATPase subunit K15583 oppD; oligopeptide transport system ATP-binding protein D Spith_0264 oligopeptide/dipeptide ABC transporter, ATPase subunit K10823 oppF; oligopeptide transport system ATP-binding protein D Spith_0760 ABC-type transporter, periplasmic subunit K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Spith_1800 ABC-type transporter, periplasmic subunit K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Spith_1941 ABC-type transporter, periplasmic subunit K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Spith_0761 ABC-type transporter, integral membrane subunit K02033 ABC.PE.P; peptide/nickel transport system permease protein D Spith_1799 ABC-type transporter, integral membrane subunit K02033 ABC.PE.P; peptide/nickel transport system permease protein D Spith_0762 ABC-type transporter, integral membrane subunit K02034 ABC.PE.P1; peptide/nickel transport system permease protein D Spith_1798 ABC-type transporter, integral membrane subunit K02034 ABC.PE.P1; peptide/nickel transport system permease protein D Spith_0763 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein D Spith_1797 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein D Spith_0008 Membrane protein oxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase D Spith_0506 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Spith_1007 preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Spith_0538 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Spith_1998 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Spith_1416 Protein translocase subunit secA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Spith_1283 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Spith_1078 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis [PATH:stq02030] D Spith_0087 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_0093 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_0100 methyl-accepting chemotaxis sensory transducer with Cache sensor K03406 mcp; methyl-accepting chemotaxis protein D Spith_0101 methyl-accepting chemotaxis sensory transducer with Cache sensor K03406 mcp; methyl-accepting chemotaxis protein D Spith_0107 hypothetical protein K03406 mcp; methyl-accepting chemotaxis protein D Spith_0231 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_0185 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_0204 methyl-accepting chemotaxis sensory transducer with Cache sensor K03406 mcp; methyl-accepting chemotaxis protein D Spith_0375 methyl-accepting chemotaxis sensory transducer with Cache sensor K03406 mcp; methyl-accepting chemotaxis protein D Spith_1194 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_1332 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_1582 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_1659 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_2125 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_2140 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_2145 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_0425 periplasmic binding protein/LacI transcriptional regulator K10439 rbsB; ribose transport system substrate-binding protein D Spith_2099 periplasmic binding protein/LacI transcriptional regulator K10439 rbsB; ribose transport system substrate-binding protein D Spith_0104 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spith_1794 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spith_0106 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW D Spith_0905 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW D Spith_1793 MCP methyltransferase, CheR-type K03408 cheW; purine-binding chemotaxis protein CheW D Spith_0105 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_0817 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_0330 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_1190 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_1791 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_0337 CheC, inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC D Spith_0329 hypothetical protein K03409 cheX; chemotaxis protein CheX D Spith_1792 CheC domain protein K03409 cheX; chemotaxis protein CheX D Spith_1060 CheC domain protein K03409 cheX; chemotaxis protein CheX D Spith_0110 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spith_2234 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spith_0109 CheD K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44] D Spith_0108 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Spith_2235 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Spith_0861 flagellar motor switch protein FliG K02410 fliG; flagellar motor switch protein FliG D Spith_0936 flagellar motor switch protein FliG K02410 fliG; flagellar motor switch protein FliG D Spith_0948 flagellar motor switch protein FliM K02416 fliM; flagellar motor switch protein FliM D Spith_0949 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Spith_0945 MotA/TolQ/ExbB proton channel K02556 motA; chemotaxis protein MotA D Spith_0946 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB C 02040 Flagellar assembly [PATH:stq02040] D Spith_0934 flagellar hook-basal body complex subunit FliE K02408 fliE; flagellar hook-basal body complex protein FliE D Spith_0935 flagellar M-ring protein FliF K02409 fliF; flagellar M-ring protein FliF D Spith_0861 flagellar motor switch protein FliG K02410 fliG; flagellar motor switch protein FliG D Spith_0936 flagellar motor switch protein FliG K02410 fliG; flagellar motor switch protein FliG D Spith_0937 Flagellar assembly protein FliH/Type III secretion system HrpE K02411 fliH; flagellar assembly protein FliH D Spith_0938 ATPase, FliI/YscN family K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] D Spith_0939 flagellar export protein FliJ K02413 fliJ; flagellar protein FliJ D Spith_0947 flagellar basal body-associated protein FliL K02415 fliL; flagellar protein FliL D Spith_0948 flagellar motor switch protein FliM K02416 fliM; flagellar motor switch protein FliM D Spith_0949 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Spith_0950 hypothetical protein K02418 fliO; flagellar protein FliO/FliZ D Spith_0951 flagellar biosynthetic protein FliP K02419 fliP; flagellar biosynthesis protein FliP D Spith_0952 flagellar biosynthetic protein FliQ K02420 fliQ; flagellar biosynthesis protein FliQ D Spith_0953 flagellar biosynthetic protein FliR K02421 fliR; flagellar biosynthesis protein FliR D Spith_0955 flagellar biosynthesis protein FlhA K02400 flhA; flagellar biosynthesis protein FlhA D Spith_0954 flagellar biosynthetic protein FlhB K02401 flhB; flagellar biosynthesis protein FlhB D Spith_0932 flagellar basal-body rod protein FlgB K02387 flgB; flagellar basal-body rod protein FlgB D Spith_0933 flagellar basal-body rod protein FlgC K02388 flgC; flagellar basal-body rod protein FlgC D Spith_0942 flagellar hook capping protein K02389 flgD; flagellar basal-body rod modification protein FlgD D Spith_0943 flagellar hook-basal body protein K02390 flgE; flagellar hook protein FlgE D Spith_1429 flagellar basal-body rod protein FlgF K02391 flgF; flagellar basal-body rod protein FlgF D Spith_1428 flagellar basal-body rod protein FlgG K02392 flgG; flagellar basal-body rod protein FlgG D Spith_1427 Flagellar protein FlgJ K02395 flgJ; peptidoglycan hydrolase FlgJ D Spith_1404 flagellar hook-associated protein FlgK K02396 flgK; flagellar hook-associated protein 1 D Spith_1403 flagellar hook-associated protein 3 K02397 flgL; flagellar hook-associated protein 3 FlgL D Spith_1097 flagellin domain protein K02406 fliC; flagellin D Spith_1392 flagellin domain protein K02406 fliC; flagellin D Spith_1393 flagellin domain protein K02406 fliC; flagellin D Spith_1395 flagellar hook-associated 2 domain-containing protein K02407 fliD; flagellar hook-associated protein 2 D Spith_0223 flagellar protein FliS K02422 fliS; flagellar secretion chaperone FliS D Spith_0945 MotA/TolQ/ExbB proton channel K02556 motA; chemotaxis protein MotA D Spith_0946 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB D Spith_0413 RNA polymerase, sigma 70 subunit, RpoD subfamily K03086 rpoD; RNA polymerase primary sigma factor D Spith_1426 RNA polymerase, sigma 70 subunit, RpoD subfamily K03086 rpoD; RNA polymerase primary sigma factor D Spith_1110 RNA polymerase, sigma 70 subunit, RpoD subfamily K03086 rpoD; RNA polymerase primary sigma factor D Spith_1037 RNA polymerase, sigma 70 subunit, RpoD subfamily K03086 rpoD; RNA polymerase primary sigma factor D Spith_2240 RNA polymerase, sigma 54 subunit, RpoN K03092 rpoN; RNA polymerase sigma-54 factor D Spith_0959 RNA polymerase, sigma 28 subunit, FliA/WhiG K02405 fliA; RNA polymerase sigma factor FliA C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D Spith_2058 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism [PATH:stq04980] D Spith_1038 ATP/cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D Spith_0199 methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance [PATH:stq01501] D Spith_0768 glycoside hydrolase family 3 domain protein K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] D Spith_1407 glycoside hydrolase family 3 domain protein K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] D Spith_0260 ABC-type transporter, periplasmic subunit K15580 oppA; oligopeptide transport system substrate-binding protein D Spith_0261 ABC-type transporter, integral membrane subunit K15581 oppB; oligopeptide transport system permease protein D Spith_0262 ABC-type transporter, integral membrane subunit K15582 oppC; oligopeptide transport system permease protein D Spith_0263 oligopeptide/dipeptide ABC transporter, ATPase subunit K15583 oppD; oligopeptide transport system ATP-binding protein D Spith_0264 oligopeptide/dipeptide ABC transporter, ATPase subunit K10823 oppF; oligopeptide transport system ATP-binding protein D Spith_2213 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Spith_2212 outer membrane efflux protein K18139 oprM; outer membrane protein, multidrug efflux system D Spith_1982 hypothetical protein K12340 tolC; outer membrane protein D Spith_1441 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Spith_1116 penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D Spith_1419 penicillin-binding protein transpeptidase K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] C 01502 Vancomycin resistance [PATH:stq01502] D Spith_0613 D-alanine--D-alanine ligase domain protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Spith_1828 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Spith_0608 Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D Spith_0919 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D Spith_0920 Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D Spith_0562 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D Spith_1700 peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:stq01503] D Spith_0990 cell wall hydrolase/autolysin K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D Spith_2156 peptidase S1 and S6 chymotrypsin/Hap K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_1808 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_1014 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_1072 PDZ/DHR/GLGF domain protein K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_2213 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Spith_1982 hypothetical protein K12340 tolC; outer membrane protein B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:stq01000] C 01001 Protein kinases [BR:stq01001] D Spith_1456 serine/threonine protein kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] D Spith_0558 multi-sensor signal transduction histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D Spith_2245 integral membrane sensor signal transduction histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] D Spith_0305 PAS/PAC sensor signal transduction histidine kinase K07710 atoS; two-component system, NtrC family, sensor histidine kinase AtoS [EC:2.7.13.3] D Spith_0104 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spith_1794 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spith_1331 integral membrane sensor signal transduction histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D Spith_0090 response regulator receiver sensor signal transduction histidine kinase K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] C 01009 Protein phosphatases and associated proteins [BR:stq01009] D Spith_0012 Adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D Spith_0248 phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spith_2013 Chaperone protein htpG K04079 HSP90A; molecular chaperone HtpG C 01002 Peptidases and inhibitors [BR:stq01002] D Spith_2186 Lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] D Spith_1581 peptidase A24A prepilin type IV K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D Spith_1028 GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Spith_1291 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D Spith_1049 ferredoxin-dependent glutamate synthase K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] D Spith_0240 sugar isomerase (SIS) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Spith_0173 Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Spith_0646 ThiJ/PfpI domain-containing protein K05520 yhbO; deglycase [EC:3.5.1.124] D Spith_1872 DJ-1 family protein K03152 thiJ; protein deglycase [EC:3.5.1.124] D Spith_0880 Abortive infection protein K07052 K07052; CAAX protease family protein D Spith_1310 Abortive infection protein K07052 K07052; CAAX protease family protein D Spith_0700 Abortive infection protein K07052 K07052; CAAX protease family protein D Spith_1899 oligoendopeptidase F K08602 pepF; oligoendopeptidase F [EC:3.4.24.-] D Spith_1700 peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D Spith_2021 Peptidase M16C associated domain protein K06972 PITRM1; presequence protease [EC:3.4.24.-] D Spith_1890 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D Spith_0269 peptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] D Spith_0237 peptidase dimerization domain protein K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] D Spith_1013 methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D Spith_1103 methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D Spith_0628 M24 family peptidase-like protein K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9] D Spith_0478 peptidase M24 K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] D Spith_0453 peptidase M28 K19701 ywaD; aminopeptidase YwaD [EC:3.4.11.6 3.4.11.10] D Spith_0113 leucyl aminopeptidase K19689 ampS; aminopeptidase [EC:3.4.11.-] D Spith_1662 peptidase M32 carboxypeptidase Taq metallopeptidase K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19] D Spith_1070 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D Spith_1541 peptidase M48 Ste24p K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D Spith_0845 membrane-associated zinc metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] D Spith_2156 peptidase S1 and S6 chymotrypsin/Hap K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_1808 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_1014 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_1072 PDZ/DHR/GLGF domain protein K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_1851 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D Spith_0602 ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D Spith_0574 ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D Spith_0600 anti-sigma H sporulation factor, LonB K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] D Spith_1699 anti-sigma H sporulation factor, LonB K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] D Spith_2247 SOS-response transcriptional repressor, LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D Spith_1165 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D Spith_1166 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D Spith_0039 carboxyl-terminal protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] D Spith_2219 Rhomboid family protein K07059 K07059; rhomboid family protein D Spith_1924 Rhomboid family protein K07059 K07059; rhomboid family protein D Spith_0930 ATP-dependent protease hslV K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2] D Spith_2216 peptidase U32 K08303 prtC; U32 family peptidase [EC:3.4.-.-] D Spith_1702 peptidase U32 K08303 prtC; U32 family peptidase [EC:3.4.-.-] D Spith_0072 alpha-2-macroglobulin domain protein K06894 yfhM; alpha-2-macroglobulin D Spith_1692 HflC protein K04087 hflC; modulator of FtsH protease HflC D Spith_1691 HflK protein K04088 hflK; modulator of FtsH protease HflK C 01003 Glycosyltransferases [BR:stq01003] D Spith_1836 glycosyl transferase family 39 K00728 POMT; dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109] D Spith_2000 glycosyl transferase group 1 K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D Spith_1409 Glycogen synthase K00703 glgA; starch synthase [EC:2.4.1.21] D Spith_0073 penicillin-binding protein 1C K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28] D Spith_1441 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Spith_0041 glycosyl transferase, WecB/TagA/CpsF family K05946 tagA; N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase [EC:2.4.1.187] D Spith_0034 glycosyl transferase group 1 K22908 mggS; mannosylglucosylglycerate synthase [EC:2.4.1.-] D Spith_0878 glycosyl transferase group 1 K22908 mggS; mannosylglucosylglycerate synthase [EC:2.4.1.-] D Spith_0236 glycosyl transferase family 2 K13693 gpgS; glucosyl-3-phosphoglycerate synthase [EC:2.4.1.266] C 01005 Lipopolysaccharide biosynthesis proteins [BR:stq01005] D Spith_1837 glycosyl transferase family 2 K20534 gtrB; polyisoprenyl-phosphate glycosyltransferase [EC:2.4.-.-] C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:stq01011] D Spith_0051 UDP-N-acetylglucosamine1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D Spith_1868 UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D Spith_1262 UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D Spith_0314 UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D Spith_1827 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D Spith_0613 D-alanine--D-alanine ligase domain protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Spith_1828 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D Spith_0608 Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D Spith_1776 Glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D Spith_0920 Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D Spith_0562 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D Spith_1858 Undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D Spith_1138 integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase D Spith_1441 penicillin-binding protein, 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D Spith_0073 penicillin-binding protein 1C K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28] D Spith_1116 penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] D Spith_1419 penicillin-binding protein transpeptidase K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D Spith_1851 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D Spith_1700 peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D Spith_1859 Lytic transglycosylase catalytic K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29] D Spith_1888 Lytic transglycosylase catalytic K08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29] D Spith_1108 aminodeoxychorismate lyase K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] D Spith_0713 rare lipoprotein A K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29] D Spith_0990 cell wall hydrolase/autolysin K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] C 01004 Lipid biosynthesis proteins [BR:stq01004] D Spith_2198 malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D Spith_0071 3-oxoacyl-(acyl-carrier-protein) synthase 3 K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D Spith_2196 3-oxoacyl-(acyl-carrier-protein) synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D Spith_0387 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spith_1224 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spith_2197 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spith_1749 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D Spith_1317 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D Spith_1690 reductase K00209 fabV; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44] D Spith_0285 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spith_1318 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spith_1549 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spith_0737 Glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D Spith_0032 phospholipid/glycerol acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D Spith_1835 phospholipid/glycerol acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:stq01006] D Spith_1786 Polyprenyl synthetase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D Spith_0848 Undecaprenyl pyrophosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D Spith_1258 tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D Spith_2031 UbiA prenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74] C 01007 Amino acid related enzymes [BR:stq01007] D Spith_0419 Lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Spith_0793 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Spith_1543 Glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18] D Spith_0795 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Spith_0805 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Spith_1867 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Spith_1048 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Spith_0311 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Spith_1644 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Spith_0441 Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Spith_0352 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Spith_0145 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Spith_0498 Asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D Spith_2263 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D Spith_1632 Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Spith_0794 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Spith_1988 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Spith_0025 Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Spith_0257 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Spith_1663 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Spith_1371 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Spith_2221 Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Spith_2222 Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Spith_0792 aminotransferase class I and II K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D Spith_1834 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] D Spith_1478 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Spith_0830 aminotransferase class I and II K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D Spith_2086 aminotransferase class I and II K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D Spith_2055 Acetylornithine/succinyldiaminopimelate aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Spith_0831 aminotransferase class-III K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62] D Spith_1672 Glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D Spith_0162 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Spith_0138 Phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:stq03000] D Spith_1705 transcriptional regulator, LysR family K02521 ilvY; LysR family transcriptional regulator, positive regulator for ilvC D Spith_1348 transcriptional regulator, DeoR family K02436 gatR; DeoR family transcriptional regulator, galactitol utilization operon repressor D Spith_0080 transcriptional regulator, LacI family K02529 galR; LacI family transcriptional regulator, galactose operon repressor D Spith_0716 transcriptional regulator, LacI family K02529 galR; LacI family transcriptional regulator, galactose operon repressor D Spith_0426 transcriptional regulator, LacI family K02529 galR; LacI family transcriptional regulator, galactose operon repressor D Spith_1522 transcriptional regulator, LacI family K02529 galR; LacI family transcriptional regulator, galactose operon repressor D Spith_1524 transcriptional regulator, LacI family K02529 galR; LacI family transcriptional regulator, galactose operon repressor D Spith_1583 transcriptional regulator, LacI family K02529 galR; LacI family transcriptional regulator, galactose operon repressor D Spith_2100 transcriptional regulator, LacI family K02529 galR; LacI family transcriptional regulator, galactose operon repressor D Spith_1892 transcriptional regulator, GntR family with LacI sensor K02103 araR; GntR family transcriptional regulator, arabinose operon transcriptional repressor D Spith_0633 GntR domain protein K05799 pdhR; GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex D Spith_2001 regulatory protein TetR K09017 rutR; TetR/AcrR family transcriptional regulator D Spith_1930 ferric uptake regulator, Fur family K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator D Spith_0172 putative transcriptional regulator, Crp/Fnr family K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spith_1430 putative transcriptional regulator, Crp/Fnr family K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein D Spith_2063 transcriptional regulator, Crp/Fnr family K21563 dnr; CRP/FNR family transcriptional regulator, dissimilatory nitrate respiration regulator D Spith_0885 transcriptional regulator, BadM/Rrf2 family K13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor D Spith_0865 transcriptional regulator, BadM/Rrf2 family K17472 cymR; Rrf2 family transcriptional regulator, cysteine metabolism repressor D Spith_1637 regulatory protein ArsR K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor D Spith_0622 transcriptional regulator, PadR-like family K10947 K10947; PadR family transcriptional regulator D Spith_0643 iron (metal) dependent repressor, DtxR family K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D Spith_0785 biotin/acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D Spith_2049 biotin/acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D Spith_1922 Trp repressor K03720 trpR; TrpR family transcriptional regulator, trp operon repressor D Spith_0836 transcriptional regulator, NifA, Fis Family K02584 nifA; Nif-specific regulatory protein D Spith_1124 transcriptional regulator, NifA subfamily, Fis Family K02584 nifA; Nif-specific regulatory protein D Spith_0139 Redox-sensing transcriptional repressor rex K01926 rex; redox-sensing transcriptional repressor D Spith_0798 Redox-sensing transcriptional repressor rex K01926 rex; redox-sensing transcriptional repressor D Spith_1512 Redox-sensing transcriptional repressor rex K01926 rex; redox-sensing transcriptional repressor D Spith_1442 ParB domain protein nuclease K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Spith_2291 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Spith_1943 transcriptional regulator, CarD family K07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription D Spith_2052 arginine repressor, ArgR K03402 argR; transcriptional regulator of arginine metabolism D Spith_1732 transcriptional regulator, TraR/DksA family K06204 dksA; RNA polymerase-binding transcription factor D Spith_1463 Transcriptional repressor nrdR K07738 nrdR; transcriptional repressor NrdR D Spith_0916 Protein mraZ K03925 mraZ; transcriptional regulator MraZ C 03021 Transcription machinery [BR:stq03021] D Spith_0293 type III restriction protein res subunit K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] D Spith_0543 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D Spith_0512 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D Spith_0513 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D Spith_1259 DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D Spith_0413 RNA polymerase, sigma 70 subunit, RpoD subfamily K03086 rpoD; RNA polymerase primary sigma factor D Spith_1426 RNA polymerase, sigma 70 subunit, RpoD subfamily K03086 rpoD; RNA polymerase primary sigma factor D Spith_1110 RNA polymerase, sigma 70 subunit, RpoD subfamily K03086 rpoD; RNA polymerase primary sigma factor D Spith_1037 RNA polymerase, sigma 70 subunit, RpoD subfamily K03086 rpoD; RNA polymerase primary sigma factor D Spith_1866 RNA polymerase, sigma-24 subunit, ECF subfamily K03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily D Spith_2240 RNA polymerase, sigma 54 subunit, RpoN K03092 rpoN; RNA polymerase sigma-54 factor D Spith_0959 RNA polymerase, sigma 28 subunit, FliA/WhiG K02405 fliA; RNA polymerase sigma factor FliA D Spith_1148 NusA antitermination factor K02600 nusA; transcription termination/antitermination protein NusA D Spith_1011 NusB antitermination factor K03625 nusB; transcription antitermination protein NusB D Spith_0507 NusG antitermination factor K02601 nusG; transcription termination/antitermination protein NusG D Spith_2273 protein serine/threonine phosphatase with GAF(s) sensor(s) K07315 rsbU_P; phosphoserine phosphatase RsbU/P [EC:3.1.3.3] D Spith_1764 protein serine/threonine phosphatase K07315 rsbU_P; phosphoserine phosphatase RsbU/P [EC:3.1.3.3] D Spith_2274 anti-sigma-factor antagonist K04749 rsbV; anti-sigma B factor antagonist D Spith_1470 anti-sigma-factor antagonist K04749 rsbV; anti-sigma B factor antagonist D Spith_1732 transcriptional regulator, TraR/DksA family K06204 dksA; RNA polymerase-binding transcription factor D Spith_2039 transcription termination factor Rho K03628 rho; transcription termination factor Rho C 03019 Messenger RNA biogenesis [BR:stq03019] D Spith_1095 Ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3] D Spith_0853 2,3 cyclic-nucleotide 2-phosphodiesterase K18682 rny; ribonucrease Y [EC:3.1.-.-] D Spith_1728 DbpA RNA-binding domain protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Spith_2058 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Spith_1142 Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D Spith_2039 transcription termination factor Rho K03628 rho; transcription termination factor Rho D Spith_0248 phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D Spith_1913 Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK D Spith_2047 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Spith_2258 polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] D Spith_0055 metal dependent phosphohydrolase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] D Spith_1631 poly(A) polymerase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] D Spith_1401 carbon storage regulator, CsrA K03563 csrA; carbon storage regulator D Spith_1633 helicase-associated domain protein K03578 hrpA; ATP-dependent RNA helicase HrpA [EC:5.6.2.6] C 03041 Spliceosome C 03011 Ribosome [BR:stq03011] D Spith_1125 Cytidylate kinase K02945 RP-S1; small subunit ribosomal protein S1 D Spith_0851 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D Spith_0524 ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D Spith_0542 ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D Spith_0535 ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D Spith_0838 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6 D Spith_0515 ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D Spith_0532 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D Spith_2161 ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D Spith_0517 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D Spith_0541 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D Spith_0514 ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D Spith_0540 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D Spith_0531 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D Spith_1143 ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D Spith_1079 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D Spith_0527 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D Spith_0840 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D Spith_0522 ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D Spith_1902 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20 D Spith_0670 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D Spith_0572 hypothetical protein K19033 PSRP4; 30S ribosomal protein S31 D Spith_0509 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D Spith_0521 ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D Spith_0518 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D Spith_0519 ribosomal protein L4/L1e K02926 RP-L4; large subunit ribosomal protein L4 D Spith_0530 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Spith_0533 ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D Spith_0842 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9 D Spith_0510 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D Spith_0508 ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Spith_0511 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D Spith_2162 ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D Spith_0528 ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D Spith_0537 ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D Spith_0525 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D Spith_0544 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D Spith_0534 ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D Spith_1083 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D Spith_1387 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D Spith_1051 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D Spith_0523 ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D Spith_0520 Ribosomal protein L25/L23 K02892 RP-L23; large subunit ribosomal protein L23 D Spith_0529 ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D Spith_1053 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D Spith_0219 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D Spith_0526 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Spith_0536 ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D Spith_2038 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D Spith_1093 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D Spith_0505 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D Spith_0005 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D Spith_1386 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D Spith_0539 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 D Spith_1067 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25 D Spith_R0011 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Spith_R0030 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Spith_R0008 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Spith_R0033 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Spith_R0010 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Spith_R0031 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:stq03009] D Spith_1095 Ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3] D Spith_0573 GTP-binding protein Era-like-protein K03595 era; GTPase D Spith_1054 GTPase obg K03979 obgE; GTPase [EC:3.6.5.-] D Spith_1732 transcriptional regulator, TraR/DksA family K06204 dksA; RNA polymerase-binding transcription factor D Spith_1148 NusA antitermination factor K02600 nusA; transcription termination/antitermination protein NusA D Spith_1011 NusB antitermination factor K03625 nusB; transcription antitermination protein NusB D Spith_0507 NusG antitermination factor K02601 nusG; transcription termination/antitermination protein NusG D Spith_1306 Ribosomal RNA small subunit methyltransferase A K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D Spith_1364 methyltransferase K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171] D Spith_1710 Ribosomal RNA small subunit methyltransferase E K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193] D Spith_0277 Ribosomal RNA small subunit methyltransferase G K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D Spith_0917 Ribosomal RNA small subunit methyltransferase H K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199] D Spith_0148 Ribosomal RNA small subunit methyltransferase I K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198] D Spith_1440 protein of unknown function DUF548 K15984 rsmJ; 16S rRNA (guanine1516-N2)-methyltransferase [EC:2.1.1.242] D Spith_0855 hemolysin A K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227] D Spith_1910 RNA methyltransferase, TrmH family, group 3 K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185] D Spith_2218 Ribosomal RNA large subunit methyltransferase E K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166] D Spith_2121 Protein of unknown function methylase putative K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191] D Spith_1370 radical SAM enzyme, Cfr family K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192] D Spith_1767 (Uracil-5)-methyltransferase K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190] D Spith_1126 pseudouridine synthase Rsu K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22] D Spith_0404 pseudouridine synthase K06179 rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24] D Spith_2182 pseudouridine synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D Spith_1780 pseudouridine synthase, RluA family K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D Spith_1081 Ribosome maturation factor rimM K02860 rimM; 16S rRNA processing protein RimM D Spith_2169 Ribosomal protein S12 methylthiotransferase rimO K14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4] D Spith_1728 DbpA RNA-binding domain protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Spith_0740 ribosome biogenesis GTPase RsgA K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D Spith_1775 Sigma 54 interacting domain protein K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D Spith_0858 GTP-binding protein engA K03977 engA; GTPase D Spith_2092 GTP-binding proten HflX K03665 hflX; GTPase D Spith_0469 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Spith_1976 (p)ppGpp synthetase I, SpoT/RelA K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D Spith_1146 Ribosome-binding factor A K02834 rbfA; ribosome-binding factor A D Spith_1149 Ribosome maturation factor rimP K09748 rimP; ribosome maturation factor RimP D Spith_1058 iojap-like protein K09710 ybeB; ribosome-associated protein D Spith_1001 metalloprotease ybeY K07042 ybeY; probable rRNA maturation factor D Spith_1823 protein of unknown function UPF0044 K07574 yhbY; RNA-binding protein D Spith_2241 ribosomal subunit interface protein K05808 hpf; ribosome hibernation promoting factor D Spith_2133 GTP-binding protein YchF K06942 ychF; ribosome-binding ATPase C 03016 Transfer RNA biogenesis [BR:stq03016] D Spith_1671 Ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11] D Spith_1096 polynucleotide adenylyltransferase/metal dependent phosphohydrolase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] D Spith_1665 protein of unknown function UPF0027 K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8] D Spith_0793 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Spith_0025 Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Spith_0257 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Spith_1644 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Spith_0352 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Spith_0311 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Spith_1543 Glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18] D Spith_1048 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Spith_0145 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Spith_1371 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Spith_0498 Asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D Spith_0794 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Spith_1663 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Spith_1988 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Spith_1867 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Spith_0441 Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Spith_1632 Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Spith_2221 Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Spith_2222 Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Spith_0795 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Spith_0805 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Spith_1132 D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96] D Spith_0334 histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D Spith_1197 tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] D Spith_1875 tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D Spith_1145 tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D Spith_1638 aminotransferase class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Spith_0469 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Spith_1258 tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D Spith_0275 tRNA modification GTPase mnmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-] D Spith_0276 tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D Spith_0006 Ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5] D Spith_R0022 RNA component of RNaseP K01978 rnpB; M1 RNA D Spith_1501 ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56] D Spith_2126 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58] D Spith_0419 Lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Spith_2263 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D Spith_0092 dihydrouridine synthase DuS K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-] D Spith_1909 TIM-barrel protein, nifR3 family K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-] D Spith_1021 (Dimethylallyl)adenosine tRNA methylthiotransferase miaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3] D Spith_1299 MiaB-like tRNA modifying enzyme K18707 mtaB; threonylcarbamoyladenosine tRNA methylthiotransferase MtaB [EC:2.8.4.5] D Spith_0144 tRNA/rRNA methyltransferase (SpoU) K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-] D Spith_1082 tRNA (guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D Spith_1538 tRNA/rRNA methyltransferase (SpoU) K00556 trmH; tRNA (guanosine-2'-O-)-methyltransferase [EC:2.1.1.34] D Spith_1986 RNA methyltransferase, TrmH family, group 2 K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207] D Spith_0151 tRNA/rRNA methyltransferase (SpoU) K03437 spoU; RNA methyltransferase, TrmH family D Spith_2093 tRNA-specific 2-thiouridylase mnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D Spith_0686 PP-loop domain protein K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA D Spith_1159 S-adenosylmethionine:tRNAribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17] D Spith_1826 6-pyruvoyl tetrahydropterin synthase and hypothetical protein K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D Spith_0187 iron-sulfur protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6] D Spith_1139 Queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29] D Spith_1639 tRNA sulfurtransferase K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D Spith_1069 tRNA(Ile)-lysidine synthase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19] D Spith_1400 universal protein YeaZ K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB D Spith_1424 O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234] D Spith_1399 Uncharacterized protein family UPF0079, ATPase K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE D Spith_1142 Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] C 03012 Translation factors [BR:stq03012] D Spith_1147 translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D Spith_1385 Translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D Spith_1971 ABC transporter related protein K06158 ABCF3; ATP-binding cassette, subfamily F, member 3 D Spith_0850 Elongation factor Ts K02357 tsf; elongation factor Ts D Spith_0516 translation elongation factor Tu K02358 tuf; elongation factor Tu D Spith_1193 translation elongation factor G K02355 fusA; elongation factor G D Spith_1195 small GTP-binding protein K02355 fusA; elongation factor G D Spith_1947 translation elongation factor G K02355 fusA; elongation factor G D Spith_1974 Peptide chain release factor 1 K02835 prfA; peptide chain release factor 1 D Spith_0849 Ribosome-recycling factor K02838 frr; ribosome recycling factor D Spith_1975 protein-(glutamine-N5) methyltransferase, release factor-specific K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D Spith_1068 Peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D Spith_1733 Translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1 D Spith_0887 Elongation factor P K02356 efp; elongation factor P D Spith_0888 tRNA synthetase class II (D K and N) K04568 epmA; elongation factor P--(R)-beta-lysine ligase [EC:6.3.1.-] D Spith_1285 Peptide chain release factor 2 K02836 prfB; peptide chain release factor 2 C 03110 Chaperones and folding catalysts [BR:stq03110] D Spith_0896 ATP-dependent Clp protease, ATP-binding subunit clpA K03694 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA D Spith_1475 ATP-dependent chaperone ClpB K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB D Spith_1276 ATPase AAA-2 domain protein K03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC D Spith_0601 ATP-dependent Clp protease ATP-binding subunit clpX K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX D Spith_0931 ATP-dependent hsl protease ATP-binding subunit hslU K03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU D Spith_2013 Chaperone protein htpG K04079 HSP90A; molecular chaperone HtpG D Spith_1913 Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK D Spith_2047 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Spith_1912 Chaperone protein dnaJ K03686 dnaJ; molecular chaperone DnaJ D Spith_1914 Protein grpE K03687 GRPE; molecular chaperone GrpE D Spith_1809 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein D Spith_1810 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein D Spith_2124 hypothetical protein K13993 HSP20; HSP20 family protein D Spith_0570 10 kDa chaperonin K04078 groES; chaperonin GroES D Spith_2156 peptidase S1 and S6 chymotrypsin/Hap K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_1808 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_1014 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_1072 PDZ/DHR/GLGF domain protein K04771 degP; serine protease Do [EC:3.4.21.107] D Spith_1070 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D Spith_0246 Glycoside hydrolase, family 20, catalytic core K12373 HEXA_B; hexosaminidase [EC:3.2.1.52] D Spith_1186 PpiC-type peptidyl-prolyl cis-trans isomerase K03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] D Spith_2016 PpiC-type peptidyl-prolyl cis-trans isomerase K03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8] D Spith_0170 thioredoxin K03671 TXN; thioredoxin D Spith_0115 thioredoxin K03671 TXN; thioredoxin D Spith_0153 glutaredoxin-like protein, YruB-family K03676 grxC; glutaredoxin 3 C 04131 Membrane trafficking [BR:stq04131] D Spith_1804 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Spith_0654 Anion-transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Spith_1004 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Spith_0102 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Spith_2013 Chaperone protein htpG K04079 HSP90A; molecular chaperone HtpG D Spith_2020 major facilitator superfamily MFS_1 K06902 UMF1; MFS transporter, UMF1 family C 04121 Ubiquitin system [BR:stq04121] C 03051 Proteasome [BR:stq03051] D Spith_2013 Chaperone protein htpG K04079 HSP90A; molecular chaperone HtpG C 03032 DNA replication proteins [BR:stq03032] D Spith_0547 Ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4] D Spith_0001 Chromosomal replication initiator protein dnaA K02313 dnaA; chromosomal replication initiator protein D Spith_0843 replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D Spith_1109 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D Spith_0839 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Spith_1361 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Spith_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Spith_2248 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Spith_0564 DNA polymerase III domain-containing protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Spith_1235 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Spith_2280 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Spith_1075 ribonuclease HII/HIII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Spith_0225 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Spith_1354 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Spith_2295 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D Spith_2296 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D Spith_0928 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] C 03036 Chromosome and associated proteins [BR:stq03036] D Spith_1095 Ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3] D Spith_0001 Chromosomal replication initiator protein dnaA K02313 dnaA; chromosomal replication initiator protein D Spith_1931 Ferritin Dps family protein K04047 dps; starvation-inducible DNA-binding protein D Spith_1076 chromosome segregation protein SMC K03529 smc; chromosome segregation protein D Spith_1128 Segregation and condensation protein A K05896 scpA; segregation and condensation protein A D Spith_1127 chromosome segregation and condensation protein, ScpB K06024 scpB; segregation and condensation protein B D Spith_0923 cell division protein FtsA K03590 ftsA; cell division protein FtsA D Spith_1419 penicillin-binding protein transpeptidase K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] D Spith_1857 cell division FtsK/SpoIIIE K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family D Spith_0918 hypothetical protein K03586 ftsL; cell division protein FtsL D Spith_0922 Polypeptide-transport-associated domain protein FtsQ-type K03589 ftsQ; cell division protein FtsQ D Spith_0921 cell division protein FtsW K03588 ftsW; cell division protein FtsW D Spith_0924 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Spith_0990 cell wall hydrolase/autolysin K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D Spith_2213 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Spith_1113 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins D Spith_1114 rod shape-determining protein MreC K03570 mreC; rod shape-determining protein MreC D Spith_1117 rod shape-determining protein RodA K05837 rodA; rod shape determining protein RodA D Spith_2292 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Spith_2224 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Spith_1442 ParB domain protein nuclease K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Spith_2291 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Spith_0276 tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D Spith_0277 Ribosomal RNA small subunit methyltransferase G K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D Spith_0929 Tyrosine recombinase xerC K03733 xerC; integrase/recombinase XerC D Spith_0925 Tyrosine recombinase xerC K04763 xerD; integrase/recombinase XerD D Spith_1883 ATPase-like, ParA/MinD K03593 mrp; ATP-binding protein involved in chromosome partitioning C 03400 DNA repair and recombination proteins [BR:stq03400] D Spith_0807 HhH-GPD family protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D Spith_2110 HhH-GPD family protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D Spith_0293 type III restriction protein res subunit K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] D Spith_1376 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Spith_1411 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Spith_1039 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Spith_1874 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] D Spith_1972 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D Spith_0668 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Spith_1354 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Spith_0225 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D Spith_1241 UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A D Spith_0550 UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B D Spith_2249 UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C D Spith_2167 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Spith_1375 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Spith_0512 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D Spith_0513 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D Spith_0543 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D Spith_1259 DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D Spith_1198 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D Spith_1153 DNA mismatch repair protein mutS K03555 mutS; DNA mismatch repair protein MutS D Spith_1772 MutS2 protein K07456 mutS2; DNA mismatch repair protein MutS2 D Spith_0678 DNA mismatch repair protein mutL K03572 mutL; DNA mismatch repair protein MutL D Spith_0984 Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D Spith_0983 Exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D Spith_1361 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D Spith_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D Spith_2248 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D Spith_0564 DNA polymerase III domain-containing protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D Spith_1235 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D Spith_2280 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D Spith_0839 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Spith_1130 Protein recA K03553 recA; recombination protein RecA D Spith_1161 Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA D Spith_1160 Holliday junction ATP-dependent DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D Spith_1162 Crossover junction endodeoxyribonuclease ruvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D Spith_1873 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D Spith_2230 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11 D Spith_0130 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms D Spith_0003 DNA replication and repair protein recF K03629 recF; DNA replication and repair protein RecF D Spith_1363 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D Spith_1698 DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O) D Spith_2278 Recombination protein recR K06187 recR; recombination protein RecR D Spith_0908 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) D Spith_0348 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1 D Spith_0697 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1 D Spith_2295 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D Spith_2296 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D Spith_0928 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D Spith_1831 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D Spith_2247 SOS-response transcriptional repressor, LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D Spith_2160 Regulatory protein recX K03565 recX; regulatory protein D Spith_0569 helicase c2 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D Spith_0218 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D Spith_0597 phosphoesterase RecJ domain protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] C 03029 Mitochondrial biogenesis [BR:stq03029] D Spith_1147 translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2 D Spith_1385 Translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D Spith_0850 Elongation factor Ts K02357 tsf; elongation factor Ts D Spith_0516 translation elongation factor Tu K02358 tuf; elongation factor Tu D Spith_1193 translation elongation factor G K02355 fusA; elongation factor G D Spith_1195 small GTP-binding protein K02355 fusA; elongation factor G D Spith_1947 translation elongation factor G K02355 fusA; elongation factor G D Spith_0573 GTP-binding protein Era-like-protein K03595 era; GTPase D Spith_0795 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Spith_0352 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Spith_0145 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D Spith_0794 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Spith_1048 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Spith_2265 Glutamyl-tRNA(Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D Spith_2264 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Spith_2266 glutamyl-tRNA(Gln) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D Spith_0839 single-strand binding protein K03111 ssb; single-strand DNA-binding protein D Spith_1155 outer membrane protein assembly complex, YaeT protein K07277 SAM50; outer membrane protein insertion porin family D Spith_1913 Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK D Spith_1914 Protein grpE K03687 GRPE; molecular chaperone GrpE D Spith_2047 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Spith_0570 10 kDa chaperonin K04078 groES; chaperonin GroES D Spith_1912 Chaperone protein dnaJ K03686 dnaJ; molecular chaperone DnaJ D Spith_1638 aminotransferase class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Spith_1883 ATPase-like, ParA/MinD K03593 mrp; ATP-binding protein involved in chromosome partitioning D Spith_0008 Membrane protein oxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase D Spith_2013 Chaperone protein htpG K04079 HSP90A; molecular chaperone HtpG B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:stq02000] D Spith_0620 ABC transporter related protein K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump D Spith_0619 ABC transporter related protein K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump D Spith_0493 ABC-type glycine betaine transport, periplasmic subunit K05845 opuC; osmoprotectant transport system substrate-binding protein D Spith_0490 ABC-type transporter, integral membrane subunit K05846 opuBD; osmoprotectant transport system permease protein D Spith_0492 ABC-type transporter, integral membrane subunit K05846 opuBD; osmoprotectant transport system permease protein D Spith_0491 ABC transporter related protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] D Spith_0499 hypothetical protein K02051 ABC.SN.S; NitT/TauT family transport system substrate-binding protein D Spith_1962 hypothetical protein K02051 ABC.SN.S; NitT/TauT family transport system substrate-binding protein D Spith_0796 ABC-type transporter, integral membrane subunit K02050 ABC.SN.P; NitT/TauT family transport system permease protein D Spith_1963 ABC-type transporter, integral membrane subunit K02050 ABC.SN.P; NitT/TauT family transport system permease protein D Spith_0797 ABC transporter related protein K02049 ABC.SN.A; NitT/TauT family transport system ATP-binding protein D Spith_1228 ABC transporter related protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D Spith_0182 ABC transporter related protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D Spith_1041 extracellular solute-binding protein family 1 K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein D Spith_1042 ABC-type transporter, integral membrane subunit K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D Spith_1043 ABC-type transporter, integral membrane subunit K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D Spith_2103 extracellular solute-binding protein family 1 K10117 msmE; raffinose/stachyose/melibiose transport system substrate-binding protein D Spith_0243 extracellular solute-binding protein family 1 K10117 msmE; raffinose/stachyose/melibiose transport system substrate-binding protein D Spith_0244 ABC-type transporter, integral membrane subunit K10118 msmF; raffinose/stachyose/melibiose transport system permease protein D Spith_2102 ABC-type transporter, integral membrane subunit K10118 msmF; raffinose/stachyose/melibiose transport system permease protein D Spith_1328 ABC-type transporter, integral membrane subunit K10118 msmF; raffinose/stachyose/melibiose transport system permease protein D Spith_2101 ABC-type transporter, integral membrane subunit K10119 msmG; raffinose/stachyose/melibiose transport system permease protein D Spith_1327 ABC-type transporter, integral membrane subunit K10119 msmG; raffinose/stachyose/melibiose transport system permease protein D Spith_0245 ABC-type transporter, integral membrane subunit K10119 msmG; raffinose/stachyose/melibiose transport system permease protein D Spith_0717 extracellular solute-binding protein family 1 K10232 aglE; alpha-glucoside transport system substrate-binding protein D Spith_0718 ABC-type transporter, integral membrane subunit K10233 aglF; alpha-glucoside transport system permease protein D Spith_0719 ABC-type transporter, integral membrane subunit K10234 aglG; alpha-glucoside transport system permease protein D Spith_1449 extracellular solute-binding protein family 1 K17315 gtsA; glucose/mannose transport system substrate-binding protein D Spith_1450 ABC-type transporter, integral membrane subunit K17316 gtsB; glucose/mannose transport system permease protein D Spith_1451 ABC-type transporter, integral membrane subunit K17317 gtsC; glucose/mannose transport system permease protein D Spith_1896 extracellular solute-binding protein family 1 K10240 cebE; cellobiose transport system substrate-binding protein D Spith_1895 ABC-type transporter, integral membrane subunit K10241 cebF; cellobiose transport system permease protein D Spith_1894 ABC-type transporter, integral membrane subunit K10242 cebG; cellobiose transport system permease protein D Spith_0355 extracellular solute-binding protein family 1 K17318 lplA; putative aldouronate transport system substrate-binding protein D Spith_0396 extracellular solute-binding protein family 1 K17318 lplA; putative aldouronate transport system substrate-binding protein D Spith_1932 sugar ABC transporter substrate-binding protein K17318 lplA; putative aldouronate transport system substrate-binding protein D Spith_0370 extracellular solute-binding protein family 1 K17318 lplA; putative aldouronate transport system substrate-binding protein D Spith_1323 extracellular solute-binding protein family 1 K17318 lplA; putative aldouronate transport system substrate-binding protein D Spith_0368 ABC-type transporter, integral membrane subunit K17319 lplB; putative aldouronate transport system permease protein D Spith_0353 ABC-type transporter, integral membrane subunit K17319 lplB; putative aldouronate transport system permease protein D Spith_0393 ABC-type transporter, integral membrane subunit K17319 lplB; putative aldouronate transport system permease protein D Spith_1325 ABC-type transporter, integral membrane subunit K17319 lplB; putative aldouronate transport system permease protein D Spith_1934 ABC-type transporter, integral membrane subunit K17319 lplB; putative aldouronate transport system permease protein D Spith_0354 ABC-type transporter, integral membrane subunit K17320 lplC; putative aldouronate transport system permease protein D Spith_0369 ABC-type transporter, integral membrane subunit K17320 lplC; putative aldouronate transport system permease protein D Spith_1933 ABC-type transporter, integral membrane subunit K17320 lplC; putative aldouronate transport system permease protein D Spith_1324 ABC-type transporter, integral membrane subunit K17320 lplC; putative aldouronate transport system permease protein D Spith_0307 transporter K10543 xylF; D-xylose transport system substrate-binding protein D Spith_0309 ABC-type transporter, integral membrane subunit K10544 xylH; D-xylose transport system permease protein D Spith_0308 ABC transporter related protein K10545 xylG; D-xylose transport system ATP-binding protein [EC:7.5.2.10] D Spith_1339 rhamnose ABC transporter, periplasmic rhamnose-binding protein K10559 rhaS; rhamnose transport system substrate-binding protein D Spith_1337 ABC-type transporter, integral membrane subunit K10560 rhaP; rhamnose transport system permease protein D Spith_1336 ABC-type transporter, integral membrane subunit K10561 rhaQ; rhamnose transport system permease protein D Spith_1338 ABC transporter related protein K10562 rhaT; rhamnose transport system ATP-binding protein [EC:7.5.2.-] D Spith_0425 periplasmic binding protein/LacI transcriptional regulator K10439 rbsB; ribose transport system substrate-binding protein D Spith_2099 periplasmic binding protein/LacI transcriptional regulator K10439 rbsB; ribose transport system substrate-binding protein D Spith_0424 ABC-type transporter, integral membrane subunit K10440 rbsC; ribose transport system permease protein D Spith_2098 ABC-type transporter, integral membrane subunit K10440 rbsC; ribose transport system permease protein D Spith_2097 ABC transporter related protein K10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7] D Spith_0423 ABC transporter related protein K10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7] D Spith_1349 extracellular solute-binding protein family 1 K25676 yesO; pectin-derived oligosaccharide transport system substrate-binding protein D Spith_1350 ABC-type transporter, integral membrane subunit K25677 yesP; pectin-derived oligosaccharide transport system permease protein D Spith_1351 ABC-type transporter, integral membrane subunit K25678 yesQ; pectin-derived oligosaccharide transport system permease protein D Spith_1845 basic membrane lipoprotein K07335 bmpA; basic membrane protein A and related proteins D Spith_1958 basic membrane lipoprotein K07335 bmpA; basic membrane protein A and related proteins D Spith_1843 ABC-type transporter, integral membrane subunit K23535 nupB; general nucleoside transport system permease protein D Spith_1956 ABC-type transporter, integral membrane subunit K23535 nupB; general nucleoside transport system permease protein D Spith_1955 ABC-type transporter, integral membrane subunit K23536 nupC; general nucleoside transport system permease protein D Spith_1842 ABC-type transporter, integral membrane subunit K23536 nupC; general nucleoside transport system permease protein D Spith_1844 ABC transporter related protein K23537 nupA; general nucleoside transport system ATP-binding protein D Spith_1957 ABC transporter related protein K23537 nupA; general nucleoside transport system ATP-binding protein D Spith_1435 Mammalian cell entry related domain protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein D Spith_1433 protein of unknown function DUF140 K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein D Spith_1434 ABC transporter related protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein D Spith_0075 extracellular solute-binding protein family 1 K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D Spith_0482 extracellular solute-binding protein family 1 K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D Spith_1529 extracellular solute-binding protein family 1 K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D Spith_1743 extracellular solute-binding protein family 1 K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D Spith_0660 extracellular solute-binding protein family 1 K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D Spith_1569 extracellular solute-binding protein family 1 K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D Spith_1745 ABC-type transporter, integral membrane subunit K02025 ABC.MS.P; multiple sugar transport system permease protein D Spith_1528 ABC-type transporter, integral membrane subunit K02025 ABC.MS.P; multiple sugar transport system permease protein D Spith_0076 ABC-type transporter, integral membrane subunit K02025 ABC.MS.P; multiple sugar transport system permease protein D Spith_0659 ABC-type transporter, integral membrane subunit K02025 ABC.MS.P; multiple sugar transport system permease protein D Spith_0483 ABC-type transporter, integral membrane subunit K02025 ABC.MS.P; multiple sugar transport system permease protein D Spith_1568 ABC-type transporter, integral membrane subunit K02025 ABC.MS.P; multiple sugar transport system permease protein D Spith_1744 ABC-type transporter, integral membrane subunit K02026 ABC.MS.P1; multiple sugar transport system permease protein D Spith_0077 ABC-type transporter, integral membrane subunit K02026 ABC.MS.P1; multiple sugar transport system permease protein D Spith_0658 ABC-type transporter, integral membrane subunit K02026 ABC.MS.P1; multiple sugar transport system permease protein D Spith_0484 ABC-type transporter, integral membrane subunit K02026 ABC.MS.P1; multiple sugar transport system permease protein D Spith_1567 ABC-type transporter, integral membrane subunit K02026 ABC.MS.P1; multiple sugar transport system permease protein D Spith_1527 ABC-type transporter, integral membrane subunit K02026 ABC.MS.P1; multiple sugar transport system permease protein D Spith_0552 phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein D Spith_0553 phosphate ABC transporter, inner membrane subunit PstC K02037 pstC; phosphate transport system permease protein D Spith_0554 phosphate ABC transporter, inner membrane subunit PstA K02038 pstA; phosphate transport system permease protein D Spith_0555 phosphate ABC transporter, ATPase subunit K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Spith_0120 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein D Spith_1953 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein D Spith_1952 ABC-type transporter, integral membrane subunit K01997 livH; branched-chain amino acid transport system permease protein D Spith_1951 ABC-type transporter, integral membrane subunit K01998 livM; branched-chain amino acid transport system permease protein D Spith_1950 ABC transporter related protein K01995 livG; branched-chain amino acid transport system ATP-binding protein D Spith_1949 ABC transporter related protein K01996 livF; branched-chain amino acid transport system ATP-binding protein D Spith_0260 ABC-type transporter, periplasmic subunit K15580 oppA; oligopeptide transport system substrate-binding protein D Spith_0261 ABC-type transporter, integral membrane subunit K15581 oppB; oligopeptide transport system permease protein D Spith_0262 ABC-type transporter, integral membrane subunit K15582 oppC; oligopeptide transport system permease protein D Spith_0263 oligopeptide/dipeptide ABC transporter, ATPase subunit K15583 oppD; oligopeptide transport system ATP-binding protein D Spith_0264 oligopeptide/dipeptide ABC transporter, ATPase subunit K10823 oppF; oligopeptide transport system ATP-binding protein D Spith_0760 ABC-type transporter, periplasmic subunit K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Spith_1800 ABC-type transporter, periplasmic subunit K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Spith_1941 ABC-type transporter, periplasmic subunit K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D Spith_0761 ABC-type transporter, integral membrane subunit K02033 ABC.PE.P; peptide/nickel transport system permease protein D Spith_1799 ABC-type transporter, integral membrane subunit K02033 ABC.PE.P; peptide/nickel transport system permease protein D Spith_0762 ABC-type transporter, integral membrane subunit K02034 ABC.PE.P1; peptide/nickel transport system permease protein D Spith_1798 ABC-type transporter, integral membrane subunit K02034 ABC.PE.P1; peptide/nickel transport system permease protein D Spith_0763 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein D Spith_1797 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein D Spith_2153 ABC-type transporter, periplasmic subunit K25034 btuF; cobalamin transport system substrate-binding protein D Spith_2152 ABC-type transporter, integral membrane subunit K25027 btuC; cobalamin transport system permease protein D Spith_2151 ABC transporter related protein K25028 btuD; cobalamin transport system ATP-binding protein [EC:7.6.2.8] D Spith_0634 ABC-type metal ion transporter, periplasmic subunit K09815 znuA; zinc transport system substrate-binding protein D Spith_0636 ABC-type transporter, integral membrane subunit K09816 znuB; zinc transport system permease protein D Spith_0635 ABC transporter related protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D Spith_1480 cobalamin (vitamin B12) biosynthesis CbiM protein K02007 cbiM; cobalt/nickel transport system permease protein D Spith_0784 BioY protein K03523 bioY; biotin transport system substrate-specific component D Spith_0782 ABC-type transporter, integral membrane subunit K16783 bioN; biotin transport system permease protein D Spith_0783 ABC transporter related protein K16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-] D Spith_1141 permease YjgP/YjgQ family protein K07091 lptF; lipopolysaccharide export system permease protein D Spith_1140 permease YjgP/YjgQ family protein K11720 lptG; lipopolysaccharide export system permease protein D Spith_2239 ABC transporter related protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5] D Spith_2076 ABC-2 type transporter K09694 nodJ; lipooligosaccharide transport system permease protein D Spith_2075 ABC transporter related protein K09695 nodI; lipooligosaccharide transport system ATP-binding protein D Spith_1504 ABC-type transport system, permease K25151 gldF; gliding motility-associated transport system permease protein D Spith_1669 ABC-type uncharacterized transport system K25151 gldF; gliding motility-associated transport system permease protein D Spith_1503 ABC transporter related protein K25152 gldA; gliding motility-associated transport system ATP-binding protein D Spith_1505 ABC-type uncharacterized transport system K25153 gldG; gliding motility-associatede transport system auxiliary component D Spith_2003 secretion protein HlyD family protein K25183 ybhG; membrane fusion protein YbhG D Spith_1279 protein of unknown function DUF214 K09808 lolC_E; lipoprotein-releasing system permease protein D Spith_1281 protein of unknown function DUF214 K09808 lolC_E; lipoprotein-releasing system permease protein D Spith_2284 protein of unknown function DUF214 K09808 lolC_E; lipoprotein-releasing system permease protein D Spith_1280 ABC transporter related protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-] D Spith_2006 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D Spith_1762 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D Spith_2007 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D Spith_1926 bacitracin ABC transporter permease K01992 ABC-2.P; ABC-2 type transport system permease protein D Spith_1927 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Spith_1497 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Spith_1761 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Spith_2004 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Spith_2005 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Spith_1670 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Spith_0191 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Spith_0446 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Spith_0447 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Spith_1978 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Spith_1979 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Spith_1035 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Spith_0192 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Spith_0193 ABC transporter related protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Spith_0448 ABC transporter related protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Spith_1980 ABC transporter related protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Spith_2286 ABC transporter related protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Spith_1034 ABC transporter related protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Spith_0590 FeS assembly ATPase SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein D Spith_1558 ABC transporter related protein K09013 sufC; Fe-S cluster assembly ATP-binding protein D Spith_1995 amino acid permease-associated region K14427 SLC12A4_6; solute carrier family 12 (potassium/chloride transporter), member 4/6 D Spith_2256 MATE efflux family protein K26937 dinF; MATE family, multidrug efflux pump D Spith_0822 MATE efflux family protein K26937 dinF; MATE family, multidrug efflux pump D Spith_2017 MATE efflux family protein K26937 dinF; MATE family, multidrug efflux pump D Spith_0206 major facilitator superfamily MFS_1 K05820 hcaT; MFS transporter, PPP family, 3-phenylpropionic acid transporter D Spith_2020 major facilitator superfamily MFS_1 K06902 UMF1; MFS transporter, UMF1 family D Spith_0857 phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D Spith_2243 Phosphotransferase system, phosphocarrier protein HPr K02784 ptsH; phosphocarrier protein HPr D Spith_2035 PTS system Galactitol-specific IIC component K02775 gatC; galactitol PTS system EIIC component D Spith_0341 putative PTS IIA-like nitrogen-regulatory protein PtsN K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-] D Spith_2281 putative PTS IIA-like nitrogen-regulatory protein PtsN K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-] D Spith_0644 putative transcriptional regulator, Crp/Fnr family K10716 kch; voltage-gated potassium channel D Spith_0835 ammonium transporter K03320 amt; ammonium transporter, Amt family D Spith_0328 multi-sensor signal transduction histidine kinase K03320 amt; ammonium transporter, Amt family D Spith_0022 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D Spith_1454 von Willebrand factor type A K07114 yfbK; Ca-activated chloride channel homolog D Spith_1737 von Willebrand factor type A K07114 yfbK; Ca-activated chloride channel homolog D Spith_1738 von Willebrand factor type A K07114 yfbK; Ca-activated chloride channel homolog D Spith_0884 MscS Mechanosensitive ion channel K05802 mscK; potassium-dependent mechanosensitive channel D Spith_0648 magnesium transporter K06213 mgtE; magnesium transporter D Spith_0945 MotA/TolQ/ExbB proton channel K02556 motA; chemotaxis protein MotA D Spith_0946 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB D Spith_0965 MotA/TolQ/ExbB proton channel K03561 exbB; biopolymer transport protein ExbB D Spith_0964 Biopolymer transport protein ExbD/TolR K03559 exbD; biopolymer transport protein ExbD D Spith_0821 magnesium and cobalt transport protein CorA K03284 corA; magnesium transporter D Spith_1718 CrcB-like protein K06199 crcB; fluoride exporter D Spith_0114 protein of unknown function DUF21 K03699 tlyC; magnesium and cobalt exporter, CNNM family D Spith_1178 OmpA/MotB domain protein K03286 TC.OOP; OmpA-OmpF porin, OOP family D Spith_1982 hypothetical protein K12340 tolC; outer membrane protein D Spith_2212 outer membrane efflux protein K18139 oprM; outer membrane protein, multidrug efflux system D Spith_1636 Soluble ligand binding domain-containing protein K01991 wza; polysaccharide biosynthesis/export protein D Spith_1155 outer membrane protein assembly complex, YaeT protein K07277 SAM50; outer membrane protein insertion porin family D Spith_1156 protein of unknown function DUF490 K09800 tamB; translocation and assembly module TamB D Spith_2238 OstA family protein K09774 lptA; lipopolysaccharide export system protein LptA D Spith_1002 CBS domain containing protein K06189 corC; hemolysin (HlyC) family protein D Spith_1500 zinc/iron permease K07238 TC.ZIP; zinc transporter, ZIP family D Spith_1092 Na+/Ca+ antiporter, CaCA family K07301 yrbG; cation:H+ antiporter D Spith_0031 Na+/glutamate symporter-like protein K03312 gltS; glutamate:Na+ symporter, ESS family D Spith_2282 sodium/hydrogen exchanger K26730 napA; Na+:H+ antiporter D Spith_0776 cation transporter K03498 trkH; trk/ktr system potassium uptake protein D Spith_0777 TrkA-N domain protein K03499 trkA; trk/ktr system potassium uptake protein D Spith_0586 Chromate transporter K07240 chrA; chromate transporter D Spith_0587 Chromate transporter K07240 chrA; chromate transporter D Spith_0384 TRAP dicarboxylate transporter, DctP subunit K11688 dctP; C4-dicarboxylate-binding protein DctP D Spith_0385 Tripartite ATP-independent periplasmic transporter DctQ component K11689 dctQ; C4-dicarboxylate transporter, DctQ subunit D Spith_2142 TRAP dicarboxylate transporter, DctM subunit K21393 yiaN; TRAP-type transport system large permease protein D Spith_2143 Tripartite ATP-independent periplasmic transporter DctQ component K21394 yiaM; TRAP-type transport system small permease protein D Spith_1488 Tripartite ATP-independent periplasmic transporter DctQ component K21394 yiaM; TRAP-type transport system small permease protein D Spith_0627 Extracellular solute-binding protein, family 7 K21395 yiaO; TRAP-type transport system periplasmic protein D Spith_1651 TRAP dicarboxylate transporter, DctP subunit K21395 yiaO; TRAP-type transport system periplasmic protein D Spith_2083 Extracellular solute-binding protein, family 7 K21395 yiaO; TRAP-type transport system periplasmic protein D Spith_2144 TRAP dicarboxylate transporter, DctP subunit K21395 yiaO; TRAP-type transport system periplasmic protein D Spith_0606 Na/Pi-cotransporter II-related protein K03324 yjbB; phosphate:Na+ symporter D Spith_0654 Anion-transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Spith_1176 Bile acid:sodium symporter K03325 ACR3; arsenite transporter D Spith_1138 integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase D Spith_0215 Auxin Efflux Carrier K24180 mleP; malate permease and related proteins D Spith_1832 Auxin Efflux Carrier K24180 mleP; malate permease and related proteins D Spith_0789 Auxin Efflux Carrier K24180 mleP; malate permease and related proteins D Spith_0741 Lysine exporter protein (LYSE/YGGA) K11249 eamB; cysteine/O-acetylserine efflux protein D Spith_0665 AzlC family protein K26605 azlC; branched chain amino acid efflux pump D Spith_0666 branched-chain amino acid transport K26606 azlD; branched chain amino acid efflux pump D Spith_0631 protein of unknown function DUF112 transmembrane K07793 tctA; putative tricarboxylic transport membrane protein D Spith_0630 hypothetical protein K07794 tctB; putative tricarboxylic transport membrane protein D Spith_0629 tricarboxylic transport K07795 tctC; putative tricarboxylic transport membrane protein D Spith_0971 protein of unknown function DUF165 K09125 yhhQ; queuosine precursor transporter D Spith_0921 cell division protein FtsW K03588 ftsW; cell division protein FtsW D Spith_0063 UPF0059 membrane protein yebN K23242 mntP; manganese efflux pump family protein D Spith_0444 Ferrous iron transport protein K07230 p19; periplasmic iron binding protein D Spith_2090 Pyrophosphate-energized proton pump K15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1] D Spith_2201 sodium ion-translocating decarboxylase, beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1] D Spith_2199 oxaloacetate decarboxylase gamma chain K01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma D Spith_1312 cytochrome c biogenesis protein transmembrane region K06196 ccdA; cytochrome c-type biogenesis protein D Spith_2213 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Spith_0641 FeoA family protein K04758 feoA; ferrous iron transport protein A D Spith_0642 ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B D Spith_0808 TspO and MBR like protein K05770 TSPO; translocator protein C 02044 Secretion system [BR:stq02044] D Spith_1982 hypothetical protein K12340 tolC; outer membrane protein D Spith_1580 type II and III secretion system protein K02453 gspD; general secretion pathway protein D D Spith_1579 type II secretion system protein E K02454 gspE; general secretion pathway protein E [EC:7.4.2.8] D Spith_1577 general secretion pathway protein G K02456 gspG; general secretion pathway protein G D Spith_1581 peptidase A24A prepilin type IV K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D Spith_1362 protein of unknown function YGGT K02221 yggT; YggT family protein D Spith_1307 ComEC/Rec2-related protein K02238 comEC; competence protein ComEC D Spith_0685 Late competence development protein ComFB K02241 comFB; competence protein ComFB D Spith_0955 flagellar biosynthesis protein FlhA K02400 flhA; flagellar biosynthesis protein FlhA D Spith_0954 flagellar biosynthetic protein FlhB K02401 flhB; flagellar biosynthesis protein FlhB D Spith_1085 type III secretion exporter K04061 flhB2; flagellar biosynthesis protein D Spith_0935 flagellar M-ring protein FliF K02409 fliF; flagellar M-ring protein FliF D Spith_0937 Flagellar assembly protein FliH/Type III secretion system HrpE K02411 fliH; flagellar assembly protein FliH D Spith_0938 ATPase, FliI/YscN family K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] D Spith_0949 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Spith_0950 hypothetical protein K02418 fliO; flagellar protein FliO/FliZ D Spith_0951 flagellar biosynthetic protein FliP K02419 fliP; flagellar biosynthesis protein FliP D Spith_0952 flagellar biosynthetic protein FliQ K02420 fliQ; flagellar biosynthesis protein FliQ D Spith_0953 flagellar biosynthetic protein FliR K02421 fliR; flagellar biosynthesis protein FliR D Spith_1416 Protein translocase subunit secA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D Spith_1997 protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD D Spith_0506 preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE D Spith_1996 protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF D Spith_1007 preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG D Spith_0538 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Spith_1078 signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Spith_1283 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Spith_1998 preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC D Spith_0008 Membrane protein oxaA K03217 yidC; YidC/Oxa1 family membrane protein insertase C 02042 Bacterial toxins [BR:stq02042] D Spith_0114 protein of unknown function DUF21 K03699 tlyC; magnesium and cobalt exporter, CNNM family C 02022 Two-component system [BR:stq02022] D Spith_0558 multi-sensor signal transduction histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D Spith_0047 transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator D Spith_2061 response regulator receiver protein K02483 K02483; two-component system, OmpR family, response regulator D Spith_2245 integral membrane sensor signal transduction histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] D Spith_2246 two component, sigma54 specific, transcriptional regulator, Fis family K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX D Spith_0042 Sigma 54 interacting domain protein K07713 zraR; two-component system, NtrC family, response regulator HydG D Spith_0305 PAS/PAC sensor signal transduction histidine kinase K07710 atoS; two-component system, NtrC family, sensor histidine kinase AtoS [EC:2.7.13.3] D Spith_0306 two component, sigma54 specific, transcriptional regulator, Fis family K07714 atoC; two-component system, NtrC family, response regulator AtoC D Spith_0104 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spith_1794 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spith_0105 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_0817 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_0330 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_1190 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_1791 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_0110 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spith_2234 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spith_1331 integral membrane sensor signal transduction histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D Spith_2141 transcriptional regulator, AraC family K07720 yesN; two-component system, response regulator YesN D Spith_1330 two component transcriptional regulator, AraC family K07720 yesN; two-component system, response regulator YesN D Spith_1340 two component transcriptional regulator, AraC family K07720 yesN; two-component system, response regulator YesN D Spith_0739 response regulator receiver K22010 pdtaR; two-component system, response regulator PdtaR D Spith_0016 response regulator receiver protein K22010 pdtaR; two-component system, response regulator PdtaR D Spith_0090 response regulator receiver sensor signal transduction histidine kinase K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] C 02035 Bacterial motility proteins [BR:stq02035] D Spith_0104 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spith_1794 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] D Spith_0106 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW D Spith_0905 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW D Spith_1793 MCP methyltransferase, CheR-type K03408 cheW; purine-binding chemotaxis protein CheW D Spith_0329 hypothetical protein K03409 cheX; chemotaxis protein CheX D Spith_1792 CheC domain protein K03409 cheX; chemotaxis protein CheX D Spith_1060 CheC domain protein K03409 cheX; chemotaxis protein CheX D Spith_0337 CheC, inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC D Spith_0109 CheD K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44] D Spith_0108 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Spith_2235 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Spith_0110 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spith_2234 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D Spith_0105 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_0817 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_0330 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_1190 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_1791 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY D Spith_0087 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_0093 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_0100 methyl-accepting chemotaxis sensory transducer with Cache sensor K03406 mcp; methyl-accepting chemotaxis protein D Spith_0101 methyl-accepting chemotaxis sensory transducer with Cache sensor K03406 mcp; methyl-accepting chemotaxis protein D Spith_0107 hypothetical protein K03406 mcp; methyl-accepting chemotaxis protein D Spith_0231 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_0185 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_0204 methyl-accepting chemotaxis sensory transducer with Cache sensor K03406 mcp; methyl-accepting chemotaxis protein D Spith_0375 methyl-accepting chemotaxis sensory transducer with Cache sensor K03406 mcp; methyl-accepting chemotaxis protein D Spith_1194 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_1332 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_1582 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_1659 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_2125 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_2140 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_2145 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein D Spith_0937 Flagellar assembly protein FliH/Type III secretion system HrpE K02411 fliH; flagellar assembly protein FliH D Spith_0938 ATPase, FliI/YscN family K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] D Spith_0939 flagellar export protein FliJ K02413 fliJ; flagellar protein FliJ D Spith_0950 hypothetical protein K02418 fliO; flagellar protein FliO/FliZ D Spith_0951 flagellar biosynthetic protein FliP K02419 fliP; flagellar biosynthesis protein FliP D Spith_0952 flagellar biosynthetic protein FliQ K02420 fliQ; flagellar biosynthesis protein FliQ D Spith_0953 flagellar biosynthetic protein FliR K02421 fliR; flagellar biosynthesis protein FliR D Spith_0955 flagellar biosynthesis protein FlhA K02400 flhA; flagellar biosynthesis protein FlhA D Spith_0954 flagellar biosynthetic protein FlhB K02401 flhB; flagellar biosynthesis protein FlhB D Spith_0861 flagellar motor switch protein FliG K02410 fliG; flagellar motor switch protein FliG D Spith_0936 flagellar motor switch protein FliG K02410 fliG; flagellar motor switch protein FliG D Spith_0948 flagellar motor switch protein FliM K02416 fliM; flagellar motor switch protein FliM D Spith_0949 flagellar motor switch protein FliN K02417 fliN; flagellar motor switch protein FliN D Spith_0935 flagellar M-ring protein FliF K02409 fliF; flagellar M-ring protein FliF D Spith_0947 flagellar basal body-associated protein FliL K02415 fliL; flagellar protein FliL D Spith_0934 flagellar hook-basal body complex subunit FliE K02408 fliE; flagellar hook-basal body complex protein FliE D Spith_0932 flagellar basal-body rod protein FlgB K02387 flgB; flagellar basal-body rod protein FlgB D Spith_0933 flagellar basal-body rod protein FlgC K02388 flgC; flagellar basal-body rod protein FlgC D Spith_0942 flagellar hook capping protein K02389 flgD; flagellar basal-body rod modification protein FlgD D Spith_1429 flagellar basal-body rod protein FlgF K02391 flgF; flagellar basal-body rod protein FlgF D Spith_1428 flagellar basal-body rod protein FlgG K02392 flgG; flagellar basal-body rod protein FlgG D Spith_1427 Flagellar protein FlgJ K02395 flgJ; peptidoglycan hydrolase FlgJ D Spith_0943 flagellar hook-basal body protein K02390 flgE; flagellar hook protein FlgE D Spith_1404 flagellar hook-associated protein FlgK K02396 flgK; flagellar hook-associated protein 1 D Spith_1403 flagellar hook-associated protein 3 K02397 flgL; flagellar hook-associated protein 3 FlgL D Spith_1097 flagellin domain protein K02406 fliC; flagellin D Spith_1392 flagellin domain protein K02406 fliC; flagellin D Spith_1393 flagellin domain protein K02406 fliC; flagellin D Spith_1395 flagellar hook-associated 2 domain-containing protein K02407 fliD; flagellar hook-associated protein 2 D Spith_0223 flagellar protein FliS K02422 fliS; flagellar secretion chaperone FliS D Spith_0959 RNA polymerase, sigma 28 subunit, FliA/WhiG K02405 fliA; RNA polymerase sigma factor FliA D Spith_0945 MotA/TolQ/ExbB proton channel K02556 motA; chemotaxis protein MotA D Spith_0946 OmpA/MotB domain protein K02557 motB; chemotaxis protein MotB D Spith_1402 Flagellar assembly factor fliW K13626 fliW; flagellar assembly factor FliW D Spith_1394 flagellar protein FlaG protein K06603 flaG; flagellar protein FlaG D Spith_0940 hypothetical protein K02383 flbB; flagellar protein FlbB D Spith_0944 flagellar FlbD family protein K02385 flbD; flagellar protein FlbD D Spith_0956 flagellar biosynthetic protein FlhF K02404 flhF; flagellar biosynthesis protein FlhF D Spith_0037 Cobyrinic acid ac-diamide synthase K04562 flhG; flagellar biosynthesis protein FlhG D Spith_0957 Cobyrinic acid ac-diamide synthase K04562 flhG; flagellar biosynthesis protein FlhG D Spith_1581 peptidase A24A prepilin type IV K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:stq04812] D Spith_0321 UPF0103/Mediator of ErbB2-driven cell motility-containing protein K06990 MEMO1; MEMO1 family protein D Spith_1666 UPF0103/Mediator of ErbB2-driven cell motility-containing protein K06990 MEMO1; MEMO1 family protein D Spith_1113 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins D Spith_0924 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Spith_0923 cell division protein FtsA K03590 ftsA; cell division protein FtsA D Spith_2292 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Spith_2224 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Spith_1442 ParB domain protein nuclease K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D Spith_2291 parB-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein C 04147 Exosome [BR:stq04147] D Spith_2013 Chaperone protein htpG K04079 HSP90A; molecular chaperone HtpG D Spith_2058 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Spith_1004 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D Spith_1005 Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Spith_0102 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D Spith_0251 peroxiredoxin K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24] D Spith_2047 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Spith_1913 Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK D Spith_2057 Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D Spith_1026 inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D Spith_0516 translation elongation factor Tu K02358 tuf; elongation factor Tu D Spith_0334 histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D Spith_0285 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spith_1318 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spith_1549 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Spith_0012 Adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1] D Spith_0903 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Spith_1423 Adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Spith_0820 Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Spith_2056 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Spith_0890 GHMP kinase K00849 galK; galactokinase [EC:2.7.1.6] D Spith_0363 galactokinase K00849 galK; galactokinase [EC:2.7.1.6] D Spith_0267 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Spith_1673 delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D Spith_1266 Alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D Spith_0137 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Spith_0389 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Spith_1019 MGS domain protein K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D Spith_1020 AICARFT/IMPCHase bienzyme formylation region K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D Spith_0736 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Spith_2050 glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D Spith_1006 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 02048 Prokaryotic defense system [BR:stq02048] D Spith_0348 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1 D Spith_0697 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1 D Spith_0349 CRISPR-associated protein Cas2 K09951 cas2; CRISPR-associated protein Cas2 D Spith_0696 CRISPR-associated protein Cas2 K09951 cas2; CRISPR-associated protein Cas2 D Spith_0695 CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] D Spith_1211 type III restriction protein res subunit K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D Spith_1216 type I site-specific deoxyribonuclease HsdR family K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D Spith_1214 restriction modification system DNA specificity domain-containing protein K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D Spith_1210 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D Spith_1212 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D Spith_1825 D12 class N6 adenine-specific DNA methyltransferase K07318 K07318; adenine-specific DNA-methyltransferase [EC:2.1.1.72] D Spith_0924 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Spith_1113 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins D Spith_0793 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Spith_1638 aminotransferase class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules C 01504 Antimicrobial resistance genes [BR:stq01504] D Spith_1700 peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D Spith_2213 efflux transporter, RND family, MFP subunit K03585 acrA; membrane fusion protein, multidrug efflux system D Spith_2212 outer membrane efflux protein K18139 oprM; outer membrane protein, multidrug efflux system D Spith_1982 hypothetical protein K12340 tolC; outer membrane protein C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:stq00537] D Spith_1266 Alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:stq03100] D Spith_R0009 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Spith_R0017 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Spith_R0048 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Spith_R0044 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spith_R0001 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spith_R0002 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spith_R0015 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spith_R0053 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Spith_R0027 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Spith_R0025 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Spith_R0043 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Spith_R0035 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Spith_R0021 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Spith_R0034 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Spith_R0019 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Spith_R0041 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Spith_R0012 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Spith_R0026 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Spith_R0016 tRNA-His K14226 tRNA-His; tRNA His D Spith_R0032 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Spith_R0047 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spith_R0004 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spith_R0013 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spith_R0049 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spith_R0029 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Spith_R0014 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Spith_R0018 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Spith_R0037 tRNA-Met K14230 tRNA-Met; tRNA Met D Spith_R0038 tRNA-Met K14230 tRNA-Met; tRNA Met D Spith_R0005 tRNA-Met K14230 tRNA-Met; tRNA Met D Spith_R0028 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Spith_R0003 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Spith_R0024 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Spith_R0045 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Spith_R0051 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spith_R0052 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spith_R0054 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spith_R0055 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Spith_R0040 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Spith_R0006 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Spith_R0036 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Spith_R0007 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Spith_R0039 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Spith_R0042 tRNA-Val K14237 tRNA-Val; tRNA Val D Spith_R0046 tRNA-Val K14237 tRNA-Val; tRNA Val D Spith_R0020 tRNA-Val K14237 tRNA-Val; tRNA Val D Spith_R0008 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Spith_R0033 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Spith_R0010 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Spith_R0031 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Spith_R0011 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Spith_R0030 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Spith_R0050 RNA component of signal recognition particle K01983 ffs; SRP RNA D Spith_R0022 RNA component of RNaseP K01978 rnpB; M1 RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D Spith_1645 short-chain dehydrogenase/reductase SDR K00046 idnO; gluconate 5-dehydrogenase [EC:1.1.1.69] D Spith_0714 iron-containing alcohol dehydrogenase K19955 adh2; alcohol dehydrogenase [EC:1.1.1.-] D Spith_1180 hypothetical protein K21430 yliI; aldose sugar dehydrogenase [EC:1.1.5.-] D Spith_1359 hypothetical protein K03518 coxS; aerobic carbon-monoxide dehydrogenase small subunit [EC:1.2.5.3] D Spith_0282 Saccharopine dehydrogenase K27502 E1.5.1.55; carboxyaminopropylagmatine dehydrogenase [EC:1.5.1.55] D Spith_2137 ferredoxin thioredoxin reductase beta chain K17892 FTRC; ferredoxin-thioredoxin reductase catalytic chain [EC:1.8.7.2] D Spith_0085 alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D Spith_1977 thiol peroxidase K11065 tpx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D Spith_1509 hypothetical protein K17992 hndB; NADP-reducing hydrogenase subunit HndB [EC:1.12.1.3] D Spith_1508 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18331 hndC; NADP-reducing hydrogenase subunit HndC [EC:1.12.1.3] D Spith_1507 hydrogenase, Fe-only K18332 hndD; NADP-reducing hydrogenase subunit HndD [EC:1.12.1.3] D Spith_0220 Desulfoferrodoxin ferrous iron-binding region K05919 dfx; superoxide reductase [EC:1.15.1.2] D Spith_1296 oxidoreductase FAD/NAD(P)-binding domain protein K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D Spith_0435 protein tyrosine phosphatase K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4] D Spith_1466 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Spith_1202 Radical SAM domain protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Spith_2174 Radical SAM domain protein K04070 pflX; putative pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Spith_1537 Protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] D Spith_1929 RNA methylase K07444 ypsC; putative N6-adenine-specific DNA methylase [EC:2.1.1.-] D Spith_0304 Apolipoprotein N-acyltransferase K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269] D Spith_1900 Apolipoprotein N-acyltransferase K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269] D Spith_0897 Leucyl/phenylalanyl-tRNA--protein transferase K00684 aat; leucyl/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6] D Spith_1763 arginyl-tRNA--protein transferase K21420 bpt; leucyl-tRNA---protein transferase [EC:2.3.2.29] D Spith_1565 glycoside hydrolase family 65 central catalytic K18783 E2.4.1.279; nigerose phosphorylase [EC:2.4.1.279] D Spith_0081 glycosidase related protein K16212 mgp; 4-O-beta-D-mannosyl-D-glucose phosphorylase [EC:2.4.1.281] D Spith_0074 glycosidase related protein K18785 mp2; beta-1,4-mannooligosaccharide/beta-1,4-mannosyl-N-acetylglucosamine phosphorylase [EC:2.4.1.319 2.4.1.320] D Spith_1807 glycosidase related protein K20885 K20885; beta-1,2-mannobiose phosphorylase / 1,2-beta-oligomannan phosphorylase [EC:2.4.1.339 2.4.1.340] D Spith_0877 alpha amylase catalytic region K22597 E2.4.1.352; glucosylglycerate phosphorylase [EC:2.4.1.352] D Spith_1917 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143] D Spith_0035 Prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145] D Spith_2227 ApbE family lipoprotein K03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180] D Spith_0028 phosphatidate cytidylyltransferase K18678 VTE5; phytol kinase [EC:2.7.1.182] D Spith_0826 glutamate-ammonia ligase adenylyltransferase K00982 glnE; [glutamine synthetase] adenylyltransferase / [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase [EC:2.7.7.42 2.7.7.89] D Spith_1879 Conserved hypothetical protein CHP00159 K18672 dacA; diadenylate cyclase [EC:2.7.7.85] D Spith_0057 hypothetical protein K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39] D Spith_2242 HPr kinase K06023 hprK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-] D Spith_1277 ATP:guanido phosphotransferase K19405 mcsB; protein arginine kinase [EC:2.7.14.1] D Spith_0778 protein of unknown function DUF303 acetylesterase K05970 SIAE; sialate O-acetylesterase [EC:3.1.1.53] D Spith_1703 protein of unknown function DUF303 acetylesterase K05970 SIAE; sialate O-acetylesterase [EC:3.1.1.53] D Spith_2073 Appr-1-p processing domain protein K23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106] D Spith_1432 PHP domain protein K07053 E3.1.3.97; 3',5'-nucleoside bisphosphate phosphatase [EC:3.1.3.97] D Spith_2252 putative phosphohistidine phosphatase, SixA K08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-] D Spith_1000 7TM receptor with intracellular metal dependent phosphohydrolase K07037 pgpH; cyclic-di-AMP phosphodiesterase PgpH [EC:3.1.4.-] D Spith_1908 hydrolase, TatD family K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D Spith_1377 hydrolase, TatD family K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D Spith_0712 glycoside hydrolase family 10 K01181 E3.2.1.8; endo-1,4-beta-xylanase [EC:3.2.1.8] D Spith_1839 glycoside hydrolase family 10 K01181 E3.2.1.8; endo-1,4-beta-xylanase [EC:3.2.1.8] D Spith_1319 glycoside hydrolase family 10 K01181 E3.2.1.8; endo-1,4-beta-xylanase [EC:3.2.1.8] D Spith_1939 glycoside hydrolase family 10 K01181 E3.2.1.8; endo-1,4-beta-xylanase [EC:3.2.1.8] D Spith_0360 glycosyl hydrolase 53 domain protein K01224 E3.2.1.89; arabinogalactan endo-1,4-beta-galactosidase [EC:3.2.1.89] D Spith_0752 hypothetical protein K06113 abnA; arabinan endo-1,5-alpha-L-arabinosidase [EC:3.2.1.99] D Spith_1532 Glycosyl hydrolase 67 middle domain protein K01235 aguA; alpha-glucuronidase [EC:3.2.1.139] D Spith_0372 glycosyl hydrolase BNR repeat-containing protein K18578 CEL74A; xyloglucan-specific exo-beta-1,4-glucanase [EC:3.2.1.155] D Spith_0376 glycosyl hydrolase family 88 K15532 yteR; unsaturated rhamnogalacturonyl hydrolase [EC:3.2.1.172] D Spith_1352 glycosyl hydrolase family 88 K15532 yteR; unsaturated rhamnogalacturonyl hydrolase [EC:3.2.1.172] D Spith_0365 glycoside hydrolase family 31 K01811 xylS; alpha-D-xyloside xylohydrolase [EC:3.2.1.177] D Spith_1746 glycosyl hydrolase family 88 K18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180] D Spith_2080 Peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D Spith_0664 polysaccharide deacetylase K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104] D Spith_0209 endoribonuclease L-PSP K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10] D Spith_1741 ATPase associated with various cellular activities AAA_3 K03924 moxR; MoxR-like ATPase [EC:3.6.3.-] D Spith_1414 YjeF-related protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6] D Spith_1748 Heparinase II/III family protein K20525 alg17C; oligo-alginate lyase [EC:4.2.2.26] D Spith_1918 Conserved hypothetical protein CHP00268 K06864 larE; pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase [EC:4.4.1.37] D Spith_1919 UPF0272 protein K09121 larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12] D Spith_0082 N-acylglucosamine 2-epimerase K16213 cbe; cellobiose epimerase [EC:5.1.3.11] D Spith_0422 RbsD or FucU transport K02431 fucU; L-fucose mutarotase [EC:5.1.3.29] D Spith_1335 L-rhamnose mutarotase K03534 rhaM; L-rhamnose mutarotase [EC:5.1.3.32] D Spith_0873 electron transport complex, RnfABCDGE type, D subunit K03614 rnfD; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit D [EC:7.1.1.11 7.2.1.2] D Spith_0461 hypothetical protein K03614 rnfD; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit D [EC:7.1.1.11 7.2.1.2] D Spith_0874 Electron transport complex protein rnfC K03615 rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] D Spith_0460 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K03615 rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] D Spith_0875 electron transport complex, RnfABCDGE type, B subunit K03616 rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] D Spith_0295 NQR2 and RnfD family protein K00347 nqrB; Na+-transporting NADH:ubiquinone oxidoreductase subunit B [EC:7.2.1.1] D Spith_0296 FMN-binding domain protein K00348 nqrC; Na+-transporting NADH:ubiquinone oxidoreductase subunit C [EC:7.2.1.1] D Spith_0297 NADH:ubiquinone oxidoreductase, subunit D K00349 nqrD; Na+-transporting NADH:ubiquinone oxidoreductase subunit D [EC:7.2.1.1] D Spith_0298 RnfA-Nqr electron transport subunit K00350 nqrE; Na+-transporting NADH:ubiquinone oxidoreductase subunit E [EC:7.2.1.1] D Spith_0299 Oxidoreductase FAD-binding domain protein K00351 nqrF; Na+-transporting NADH:ubiquinone oxidoreductase subunit F [EC:7.2.1.1] D Spith_0781 heavy metal translocating P-type ATPase K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21] C 99981 Carbohydrate metabolism D Spith_1948 CBS domain containing membrane protein K04767 acuB; acetoin utilization protein AcuB C 99982 Energy metabolism D Spith_2164 hypothetical protein K05337 fer; ferredoxin D Spith_1204 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K05337 fer; ferredoxin D Spith_0872 electron transport complex, RnfABCDGE type, G subunit K03612 rnfG; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit G D Spith_0871 electron transport complex, RnfABCDGE type, E subunit K03613 rnfE; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit E D Spith_0463 hypothetical protein K03613 rnfE; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit E D Spith_0870 electron transport complex, RnfABCDGE type, A subunit K03617 rnfA; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit A D Spith_0464 hypothetical protein K03617 rnfA; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit A D Spith_0595 SUF system FeS assembly protein, NifU family K04488 iscU; nitrogen fixation protein NifU and related proteins C 99983 Lipid metabolism C 99984 Nucleotide metabolism C 99985 Amino acid metabolism D Spith_1782 protein of unknown function UPF0001 K06997 yggS; PLP dependent protein C 99986 Glycan metabolism C 99987 Cofactor metabolism D Spith_1490 von Willebrand factor type A K13580 K13580; magnesium chelatase subunit ChlD-like protein C 99988 Secondary metabolism C 99999 Others B B 09192 Unclassified: genetic information processing C 99973 Transcription D Spith_0834 nitrogen regulatory protein P-II K04752 glnK; nitrogen regulatory protein P-II 2 C 99974 Translation C 99975 Protein processing D Spith_0895 ATP-dependent Clp protease adapter protein clpS K06891 clpS; ATP-dependent Clp protease adaptor protein ClpS D Spith_1278 UvrB/UvrC protein K19411 mcsA; protein arginine kinase activator D Spith_0603 Trigger factor K03545 tig; trigger factor D Spith_1168 SsrA-binding protein K03664 smpB; SsrA-binding protein D Spith_2138 glutaredoxin K06191 nrdH; glutaredoxin-like protein NrdH D Spith_0548 Mg chelatase, subunit ChlI K07391 comM; magnesium chelatase family protein D Spith_0152 OsmC family protein K07397 yhfA; putative redox protein C 99976 Replication and repair D Spith_0868 DNA repair protein RadC K03630 radC; DNA repair protein RadC D Spith_0415 HhH-GPD family protein K07457 K07457; endonuclease III related protein D Spith_1087 UPF0102 protein yraN K07460 yraN; putative endonuclease D Spith_0927 DNA protecting protein DprA K04096 smf; DNA processing protein D Spith_0604 AAA ATPase central domain protein K07478 ycaJ; putative ATPase D Spith_0657 transposase-like protein K07488 K07488; transposase D Spith_0757 transposase-like protein K07488 K07488; transposase D Spith_0374 transposase-like protein K07488 K07488; transposase D Spith_0818 transposase-like protein K07488 K07488; transposase D Spith_2114 transposase-like protein K07488 K07488; transposase D Spith_2104 transposase-like protein K07488 K07488; transposase D Spith_1552 transposase-like protein K07488 K07488; transposase D Spith_1205 transposase-like protein K07488 K07488; transposase D Spith_1649 transposase-like protein K07488 K07488; transposase D Spith_0343 transposase-like protein K07488 K07488; transposase D Spith_0405 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_0456 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_0753 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_0395 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_0472 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_0504 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_0823 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_0832 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_0819 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_0968 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_0899 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_1061 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_1526 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_1150 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_1206 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_1594 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_1999 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_2026 hypothetical protein K07493 K07493; putative transposase D Spith_2071 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_2081 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_2183 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_2208 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_2210 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_1481 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_1297 MULE transposase, conserved domain-containing protein K07493 K07493; putative transposase D Spith_0476 transposase IS3/IS911 family protein K07497 K07497; putative transposase D Spith_0344 transposase IS3/IS911 family protein K07497 K07497; putative transposase D Spith_1518 transposase IS3/IS911 family protein K07497 K07497; putative transposase D Spith_1588 transposase IS3/IS911 family protein K07497 K07497; putative transposase D Spith_2118 Integrase catalytic region K07497 K07497; putative transposase D Spith_1752 transposase IS3/IS911 family protein K07497 K07497; putative transposase D Spith_1755 transposase IS3/IS911 family protein K07497 K07497; putative transposase D Spith_1473 transposase IS3/IS911 family protein K07497 K07497; putative transposase D Spith_1553 transposase IS3/IS911 family protein K07497 K07497; putative transposase C 99979 Viral proteins C 99998 Others D Spith_0046 phage shock protein A, PspA K03969 pspA; phage shock protein A D Spith_2279 UPF0133 protein ybaB K09747 ebfC; nucleoid-associated protein EbfC B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D Spith_2206 sugar (Glycoside-Pentoside-Hexuronide) transporter K03292 TC.GPH; glycoside/pentoside/hexuronide:cation symporter, GPH family D Spith_2214 acriflavin resistance protein K03296 TC.HAE1; hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 family C 99978 Cell growth D Spith_0009 single-stranded nucleic acid binding R3H domain-containing protein K06346 jag; spoIIIJ-associated protein D Spith_1066 septation protein spoVG K06412 spoVG; stage V sporulation protein G D Spith_0987 acylneuraminate cytidylyltransferase K07257 spsF; spore coat polysaccharide biosynthesis protein SpsF C 99993 Cell motility C 99995 Signaling proteins D Spith_0999 PhoH family protein K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins D Spith_0221 PhoH family protein K07175 phoH2; PhoH-like ATPase D Spith_0254 AAA ATPase K08482 kaiC; circadian clock protein KaiC C 99992 Structural proteins D Spith_1154 outer membrane chaperone Skp (OmpH) K06142 hlpA; outer membrane protein D Spith_1981 efflux transporter, RND family, MFP subunit K02005 ABC.CD.TX; HlyD family secretion protein D Spith_0801 protein of unknown function UPF0118 K11744 tqsA; AI-2 transport protein TqsA D Spith_2170 transcriptional regulator, XRE family K15539 rodZ; cytoskeleton protein RodZ C 99994 Others D Spith_0560 phosphate uptake regulator, PhoU K02039 phoU; phosphate transport system protein B B 09194 Poorly characterized C 99996 General function prediction only D Spith_0563 Colicin V production protein K03558 cvpA; membrane protein required for colicin V production D Spith_0689 DEAD/DEAH box helicase domain protein K06877 K06877; DEAD/DEAH box helicase domain-containing protein D Spith_0229 Patatin K07001 K07001; NTE family protein D Spith_0266 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 K07025; putative hydrolase of the HAD superfamily D Spith_1101 Haloacid dehalogenase domain protein hydrolase K07025 K07025; putative hydrolase of the HAD superfamily D Spith_1916 HAD-superfamily hydrolase, subfamily IA, variant 1 K07025 K07025; putative hydrolase of the HAD superfamily D Spith_0591 FeS assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB D Spith_0592 SufBD protein K09015 sufD; Fe-S cluster assembly protein SufD D Spith_0688 aryldialkylphosphatase K07048 PTER; phosphotriesterase-related protein D Spith_1482 LemA family protein K03744 lemA; LemA protein D Spith_0227 Sporulation domain-containing protein K03749 dedD; DedD protein C 99997 Function unknown D Spith_0974 Ankyrin K06867 K06867; uncharacterized protein D Spith_1483 protein of unknown function DUF477 K06872 K06872; uncharacterized protein D Spith_0966 hypothetical protein K06873 K06873; uncharacterized protein D Spith_0687 metal dependent phosphohydrolase K06885 K06885; uncharacterized protein D Spith_1697 hypothetical protein K06889 K06889; uncharacterized protein D Spith_2077 protein of unknown function UPF0005 K06890 K06890; uncharacterized protein D Spith_0703 UPF0251 protein K06933 K06933; uncharacterized protein D Spith_0626 hypothetical protein K06934 K06934; uncharacterized protein D Spith_1104 protein of unknown function UPF0153 K06940 K06940; uncharacterized protein D Spith_1080 UPF0109 protein K06960 K06960; uncharacterized protein D Spith_1408 GCN5-related N-acetyltransferase K06976 K06976; uncharacterized protein D Spith_1542 protein of unknown function DUF861 cupin_3 K06995 K06995; uncharacterized protein D Spith_0812 MMPL domain protein K07003 K07003; uncharacterized protein D Spith_1183 DNA polymerase beta domain protein region K07075 K07075; uncharacterized protein D Spith_1630 DNA polymerase beta domain protein region K07075 K07075; uncharacterized protein D Spith_1595 DNA polymerase beta domain protein region K07075 K07075; uncharacterized protein D Spith_0059 aldo/keto reductase K07079 K07079; uncharacterized protein D Spith_1171 Protein of unknown function DUF318, transmembrane K07089 K07089; uncharacterized protein D Spith_0674 metallophosphoesterase K07096 K07096; uncharacterized protein D Spith_1954 phosphoribosyltransferase K07101 K07101; uncharacterized protein D Spith_0734 protein of unknown function DUF395 YeeE/YedE K07112 K07112; uncharacterized protein D Spith_0451 short-chain dehydrogenase/reductase SDR K07124 K07124; uncharacterized protein D Spith_1852 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K07137 K07137; uncharacterized protein D Spith_0184 Conserved hypothetical protein CHP01212 K07139 K07139; uncharacterized protein D Spith_0177 protein of unknown function DUF554 K07150 K07150; uncharacterized protein D Spith_1111 protein of unknown function DUF164 K07164 K07164; uncharacterized protein D Spith_0007 UPF0161 protein yidD K08998 K08998; uncharacterized protein D Spith_0019 protein of unknown function DUF151 K08999 K08999; uncharacterized protein D Spith_1040 protein of unknown function DUF763 K09003 K09003; uncharacterized protein D Spith_0982 protein of unknown function DUF192 K09005 K09005; uncharacterized protein D Spith_2175 protein of unknown function DUF82 K09122 K09122; uncharacterized protein D Spith_1788 protein of unknown function DUF401 K09133 K09133; uncharacterized protein D Spith_1719 protein of unknown function DUF190 K09137 K09137; uncharacterized protein D Spith_0320 AMMECR1-domain protein K09141 K09141; uncharacterized protein D Spith_0454 protein of unknown function DUF369 K09143 K09143; uncharacterized protein D Spith_0625 protein of unknown function DUF438 K09155 K09155; uncharacterized protein D Spith_0894 protein of unknown function UPF0153 K09160 K09160; uncharacterized protein D Spith_0960 protein of unknown function DUF342 K09749 K09749; uncharacterized protein D Spith_0036 protein of unknown function DUF342 K09749 K09749; uncharacterized protein D Spith_0684 protein of unknown function DUF503 K09764 K09764; uncharacterized protein D Spith_1876 Protein of unknown function DUF2225 K09766 K09766; uncharacterized protein D Spith_1818 UPF0178 protein yaiI K09768 K09768; uncharacterized protein D Spith_1905 protein of unknown function DUF327 K09770 K09770; uncharacterized protein D Spith_0458 acid phosphatase/vanadium-dependent haloperoxidase related protein K09775 K09775; uncharacterized protein D Spith_1425 protein of unknown function DUF610 YibQ K09798 K09798; uncharacterized protein D Spith_0914 hypothetical protein K09942 K09942; uncharacterized protein D Spith_0268 Uncharacterized conserved protein UCP018688 K01163 K01163; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: April 27, 2024