+C Peptidoglycan biosynthesis and degradation proteins KO
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Peptidoglycan Biosynthesis and Degradation Proteins - Streptococcus pyogenes Alab49 (serotype M53)
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APrecursor biosynthesis
B Transferase/Dehydrogenase
C SPYALAB49_001105 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
C SPYALAB49_000612 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
C SPYALAB49_000823 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
B Amino acid ligase
C SPYALAB49_000322 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
C SPYALAB49_001235 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
C SPYALAB49_000354 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7]
C SPYALAB49_001156 ddl; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
C SPYALAB49_000543 femAB family protein K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10]
C SPYALAB49_000542 femAB family protein K12554 murN; alanine adding enzyme [EC:2.3.2.-]
B Racemase
C SPYALAB49_001525 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
C SPYALAB49_000332 murI; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
B Carboxypeptidase
B Glycosyltransferase
C SPYALAB49_001408 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
C SPYALAB49_001234 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
B Diphosphatase
C SPYALAB49_000271 bacitracin resistance BacA family protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
C SPYALAB49_000343 PAP2 superfamily protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]
B Flippase
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APeptidoglycan biosynthesis and degradation
B Glycosyltransferase/DD-Transpeptidase (Class A PBP)
C SPYALAB49_001397 pbp1a; penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
C SPYALAB49_000123 pbp1b; penicillin-binding protein 1B K03693 pbp1b; penicillin-binding protein 1B
C SPYALAB49_001734 penicillin-binding, 1A family protein K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4]
B DD-Transpeptidase (Class B PBP)
C SPYALAB49_001409 pbpX; penicillin-binding protein 2X K12556 pbp2X; penicillin-binding protein 2X
B DD-Carboxypeptidase/DD-Endopeptidase (Low molecular weight PBP)
C SPYALAB49_000816 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C SPYALAB49_000281 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
B Glycosyltransferase
B Transpeptidase
B Carboxypeptidase
C SPYALAB49_001495 D-alanyl-D-alanine carboxypeptidase family protein K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
B Endopeptidase
C SPYALAB49_001701 emm1.0; M protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
C SPYALAB49_000046 CHAP domain protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
B Sortase
C SPYALAB49_000872 hypothetical protein K07284 srtA; sortase A [EC:3.4.22.70]
C SPYALAB49_000150 srtB; sortase, SrtB family K08600 srtB; sortase B [EC:3.4.22.71]
B Lytic transglycosylase
C SPYALAB49_000324 aminodeoxychorismate lyase family protein K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]
B Amidase
B Structural protein
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: January 30, 2024